TMA36 RNA Seq dataset: Indolent vs. Intermediate vs. Aggressive

Pre-processing of the data

Exploring data

Batch effect

Differential gene expression analysis

## Warning in DESeqDataSet(se, design = design, ignoreRank): some variables in
## design formula are characters, converting to factors

## Warning: Setting row names on a tibble is deprecated.

DE results

Top DE genes: Heatmap

Top DE genes: Volcano plot

Top DE genes: table (cutoffs: pval<0.05, L2FC > 1.5)

• baseMean—The average of the normalized count values, dividing by size factors, taken over all samples.

• log2FoldChange–The effect size estimate. This value indicates how much the gene or transcript’s expression seems to have changed between the comparison and control groups. This value is reported on a logarithmic scale to base 2.

• lfcSE–The standard error estimate for the log2 fold change estimate.

• stat–The value of the test statistic for the gene or transcript.

• pvalue–P-value of the test for the gene or transcript.

• padj–Adjusted P-value for multiple testing for the gene or transcript.

• gene-Gene ID from ENSEMBL database

• Symbol—Gene name

baseMean	log2FoldChange	lfcSE	stat	pvalue	padj	gene	symbol
412.09909	-3.631981	0.6737470	-5.390719	0.0000001	0.0015160	ENSG00000108576.5	SLC6A4
693.53475	4.339670	0.8611857	5.039180	0.0000005	0.0035271	ENSG00000130294.10	KIF1A
440.63659	3.844206	0.7716447	4.981834	0.0000006	0.0035271	ENSG00000149948.9	HMGA2
1278.51670	2.905940	0.5922868	4.906305	0.0000009	0.0035271	ENSG00000118322.8	ATP10B
340.61147	3.200668	0.6530998	4.900733	0.0000010	0.0035271	ENSG00000197301.3	RP11-366L20.2
2266.62094	-1.820272	0.3718119	-4.895679	0.0000010	0.0035271	ENSG00000100413.12	POLR3H
410.63848	1.630370	0.3671443	4.440680	0.0000090	0.0268854	ENSG00000155974.7	GRIP1
60.39733	2.072297	0.4690457	4.418113	0.0000100	0.0268854	ENSG00000164669.8	INTS4L1
2034.67398	2.725842	0.6208947	4.390184	0.0000113	0.0271837	ENSG00000065618.12	COL17A1
256.42892	2.330335	0.5344273	4.360435	0.0000130	0.0280403	ENSG00000152669.8	CCNO
578.20476	3.387560	0.8007719	4.230368	0.0000233	0.0405399	ENSG00000178343.4	SHISA3
80.09276	2.960817	0.7023276	4.215721	0.0000249	0.0405399	ENSG00000270358.1	IGHV4-61
308.92978	-1.898780	0.4511366	-4.208879	0.0000257	0.0405399	ENSG00000167588.8	GPD1
137.72381	2.360486	0.5627363	4.194657	0.0000273	0.0405399	ENSG00000173432.6	SAA1
1422.79385	3.322626	0.7951863	4.178424	0.0000294	0.0405399	ENSG00000021826.10	CPS1
8012.75796	3.228192	0.7747062	4.166989	0.0000309	0.0405399	ENSG00000223532.5	HLA-B
95.90644	-1.899696	0.4567196	-4.159436	0.0000319	0.0405399	ENSG00000187950.4	OVCH1
205.48360	2.843440	0.6865694	4.141519	0.0000345	0.0414054	ENSG00000211936.2	IGHV4-4
104.49380	-2.175709	0.5318486	-4.090842	0.0000430	0.0488671	ENSG00000263001.1	GTF2I
147.25849	2.137299	0.5271812	4.054203	0.0000503	0.0543350	ENSG00000159263.11	SIM2
176.54440	2.072023	0.5167104	4.010028	0.0000607	0.0617755	ENSG00000130675.10	MNX1
161.33680	2.041447	0.5101567	4.001607	0.0000629	0.0617755	ENSG00000196353.7	CPNE4
21920.25729	3.218692	0.8195833	3.927230	0.0000859	0.0773439	ENSG00000117983.13	MUC5B
221.14162	2.320042	0.6059493	3.828772	0.0001288	0.0877279	ENSG00000211637.2	IGLV4-69
2404.74954	2.493557	0.6517472	3.825957	0.0001303	0.0877279	ENSG00000012223.8	LTF
1152.76926	2.654083	0.6960795	3.812902	0.0001373	0.0877279	ENSG00000127324.4	TSPAN8
89.37147	-1.725074	0.4528884	-3.809048	0.0001395	0.0877279	ENSG00000116147.12	TNR
103.45655	-1.585158	0.4162388	-3.808291	0.0001399	0.0877279	ENSG00000186188.6	FFAR4
189.18156	1.529893	0.4030889	3.795423	0.0001474	0.0877279	ENSG00000225345.3	SNX18P3
130.18020	2.382328	0.6282812	3.791819	0.0001495	0.0877279	ENSG00000105929.11	ATP6V0A4
151.85206	2.361463	0.6229553	3.790742	0.0001502	0.0877279	ENSG00000132746.10	ALDH3B2
152.82329	2.350941	0.6218646	3.780472	0.0001565	0.0877279	ENSG00000134339.4	SAA2
102.56084	2.287184	0.6050202	3.780344	0.0001566	0.0877279	ENSG00000107984.5	DKK1
58.46382	2.082975	0.5511457	3.779355	0.0001572	0.0877279	ENSG00000128655.12	PDE11A
134.33345	2.380604	0.6405086	3.716740	0.0002018	0.0990895	ENSG00000240216.3	CPHL1P
606.19033	2.116496	0.5698003	3.714453	0.0002036	0.0990895	ENSG00000170927.10	PKHD1
41.35608	1.756222	0.4728418	3.714186	0.0002039	0.0990895	ENSG00000213352.3	GAPDHP44
139.31748	1.645600	0.4434347	3.711030	0.0002064	0.0990895	ENSG00000243587.6	C6orf183
190.52330	2.165868	0.5950354	3.639897	0.0002727	0.1253593	ENSG00000176532.3	PRR15
138.66968	-2.578531	0.7109375	-3.626944	0.0002868	0.1256313	ENSG00000111218.7	PRMT8
34.74269	1.549072	0.4287405	3.613076	0.0003026	0.1257013	ENSG00000242866.5	STRC
682.85553	2.000737	0.5549325	3.605370	0.0003117	0.1270474	ENSG00000215030.4	RPL13P12
1325.32292	2.435441	0.6814891	3.573705	0.0003520	0.1382394	ENSG00000105825.7	TFPI2
457.79067	1.793309	0.5051908	3.549765	0.0003856	0.1426529	ENSG00000136883.8	KIF12
79.68468	-1.871943	0.5275699	-3.548237	0.0003878	0.1426529	ENSG00000231322.1	RPL13AP17
541.53484	2.263360	0.6381021	3.547018	0.0003896	0.1426529	ENSG00000149043.12	SYT8
87.01968	-1.988054	0.5612345	-3.542288	0.0003967	0.1428153	ENSG00000232018.4	AL132709.8
429.56039	2.322869	0.6663365	3.486030	0.0004902	0.1662492	ENSG00000137745.7	MMP13
320.45079	2.823434	0.8108533	3.482052	0.0004976	0.1662492	ENSG00000270597.1	IGHV3-48
374.96469	2.342254	0.6773678	3.457877	0.0005445	0.1739235	ENSG00000271225.1	RP11-460N11.3
147.17851	1.622599	0.4694506	3.456378	0.0005475	0.1739235	ENSG00000257818.1	RP11-1143G9.2
444.77456	1.643673	0.4765145	3.449366	0.0005619	0.1759169	ENSG00000113494.12	PRLR
59.61712	1.786258	0.5215542	3.424876	0.0006151	0.1898139	ENSG00000182931.5	WFDC10B
123.11381	1.648293	0.4819424	3.420103	0.0006260	0.1904546	ENSG00000091513.10	TF
79.82107	1.973626	0.5837215	3.381109	0.0007219	0.2067554	ENSG00000234602.3	MCIDAS
79.59603	-1.893660	0.5629428	-3.363859	0.0007686	0.2067554	ENSG00000206557.5	TRIM71
199.91675	1.710625	0.5096361	3.356561	0.0007892	0.2067554	ENSG00000074276.6	CDHR2
418.22149	2.012480	0.5996490	3.356098	0.0007905	0.2067554	ENSG00000133477.12	FAM83F
190.31691	2.196209	0.6546590	3.354738	0.0007944	0.2067554	ENSG00000119547.5	ONECUT2
226.51521	-1.846373	0.5556631	-3.322829	0.0008911	0.2238307	ENSG00000225746.4	AL132709.5
87.50416	1.915968	0.5777271	3.316390	0.0009119	0.2238472	ENSG00000138271.4	GPR87
135.10170	2.377722	0.7179031	3.312037	0.0009262	0.2248048	ENSG00000169856.7	ONECUT1
1222.93273	2.218669	0.6709419	3.306799	0.0009437	0.2265060	ENSG00000197550.3	RP11-460N11.2
88.63026	1.858719	0.5652476	3.288327	0.0010078	0.2286007	ENSG00000249628.2	LINC00942
112.61761	2.361364	0.7186627	3.285775	0.0010170	0.2286007	ENSG00000168143.8	FAM83B
634.07864	-1.786391	0.5439065	-3.284371	0.0010221	0.2286007	ENSG00000268388.1	FENDRR
77.25247	1.899421	0.5786606	3.282444	0.0010291	0.2286007	ENSG00000196228.2	SULT1C3
562.45720	1.587146	0.4838678	3.280123	0.0010376	0.2286007	ENSG00000172724.7	CCL19
109.70553	1.613052	0.4918844	3.279331	0.0010405	0.2286007	ENSG00000197584.7	KCNMB2
113.31205	1.668241	0.5090743	3.277010	0.0010491	0.2286007	ENSG00000135100.13	HNF1A
425.85491	2.061011	0.6302536	3.270129	0.0010750	0.2294283	ENSG00000106278.7	PTPRZ1
466.01192	1.860301	0.5698103	3.264773	0.0010955	0.2297610	ENSG00000073282.8	TP63
106.79355	1.867335	0.5728952	3.259471	0.0011162	0.2299936	ENSG00000237978.1	RP11-385J1.2
355.60938	-1.857350	0.5724464	-3.244583	0.0011762	0.2348964	ENSG00000183019.3	C19orf59
4440.34399	1.751780	0.5400138	3.243955	0.0011788	0.2348964	ENSG00000104368.13	PLAT
806.78201	1.510957	0.4672931	3.233423	0.0012232	0.2376057	ENSG00000156510.11	HKDC1
75.04478	1.920553	0.5943435	3.231386	0.0012319	0.2376057	ENSG00000183778.13	B3GALT5
55.16897	1.838797	0.5694933	3.228831	0.0012430	0.2376171	ENSG00000230699.2	RP11-54O7.1
2422.64294	2.118644	0.6602534	3.208836	0.0013327	0.2402173	ENSG00000179869.10	ABCA13
105.17555	-1.772803	0.5530793	-3.205333	0.0013491	0.2402173	ENSG00000271417.1	RP11-909M7.3
190.49307	2.245436	0.7015456	3.200698	0.0013709	0.2407744	ENSG00000107159.8	CA9
2961.62412	1.762533	0.5514383	3.196248	0.0013923	0.2425480	ENSG00000232931.1	LINC00342
740.62256	1.722562	0.5396769	3.191839	0.0014137	0.2431690	ENSG00000163053.6	SLC16A14
130.52422	1.658062	0.5196238	3.190890	0.0014184	0.2431690	ENSG00000104892.12	KLC3
60.91080	-1.670176	0.5247090	-3.183052	0.0014573	0.2478812	ENSG00000205426.6	KRT81
95.25069	2.028202	0.6377159	3.180417	0.0014706	0.2481925	ENSG00000129151.4	BBOX1
655.75395	3.108301	0.9808669	3.168932	0.0015300	0.2516504	ENSG00000173702.3	MUC13
966.55638	2.151746	0.6798385	3.165085	0.0015504	0.2516504	ENSG00000257017.4	HP
105.55467	2.154183	0.6818836	3.159165	0.0015822	0.2516504	ENSG00000015520.10	NPC1L1
149.47768	1.769095	0.5600680	3.158715	0.0015847	0.2516504	ENSG00000133519.8	ZDHHC8P1
128.64895	-1.670061	0.5290178	-3.156909	0.0015945	0.2516504	ENSG00000138207.8	RBP4
10097.54787	1.506121	0.4774483	3.154521	0.0016076	0.2516504	ENSG00000174501.10	ANKRD36C
303.15898	2.037063	0.6466122	3.150363	0.0016307	0.2534237	ENSG00000172927.3	MYEOV
104.24385	1.685383	0.5388942	3.127484	0.0017631	0.2682139	ENSG00000054179.7	ENTPD2
109.96882	1.950656	0.6244945	3.123575	0.0017867	0.2699013	ENSG00000233217.1	MROH3P
223.25980	1.852829	0.5957087	3.110294	0.0018690	0.2776364	ENSG00000164418.15	GRIK2
63.65404	1.930027	0.6226479	3.099708	0.0019371	0.2827406	ENSG00000105641.3	SLC5A5
178.11660	1.880334	0.6074394	3.095509	0.0019648	0.2835157	ENSG00000260604.1	RP1-140K8.5
72.69424	1.629318	0.5264497	3.094918	0.0019687	0.2835157	ENSG00000204624.6	PTCHD2
421.93943	2.021640	0.6577127	3.073744	0.0021139	0.2973412	ENSG00000148702.10	HABP2
81.94949	1.739277	0.5665507	3.069940	0.0021410	0.2973412	ENSG00000145794.12	MEGF10
453.13077	1.865199	0.6077944	3.068800	0.0021492	0.2973412	ENSG00000023839.6	ABCC2
126.42935	1.564294	0.5159768	3.031713	0.0024317	0.3242007	ENSG00000091137.7	SLC26A4
456.99179	1.984239	0.6546050	3.031201	0.0024358	0.3242007	ENSG00000196090.8	PTPRT
504.07941	2.750216	0.9135129	3.010594	0.0026074	0.3313205	ENSG00000078725.8	BRINP1
68.36329	1.694954	0.5636522	3.007093	0.0026376	0.3325802	ENSG00000152578.8	GRIA4
45.89698	1.521414	0.5061450	3.005886	0.0026481	0.3325802	ENSG00000223813.2	AC007255.8
816.49173	2.934166	0.9809572	2.991125	0.0027795	0.3337528	ENSG00000171560.10	FGA
93.96584	1.545392	0.5167246	2.990746	0.0027830	0.3337528	ENSG00000214975.4	PPIAP29
399.98559	1.726185	0.5785687	2.983544	0.0028493	0.3337528	ENSG00000165449.7	SLC16A9
161.45597	1.929680	0.6471344	2.981884	0.0028648	0.3337528	ENSG00000156413.9	FUT6
295.20190	1.995289	0.6694566	2.980460	0.0028782	0.3337528	ENSG00000114455.9	HHLA2
1763.15023	-1.657139	0.5583348	-2.968003	0.0029974	0.3337528	ENSG00000182010.6	RTKN2
1220.63122	-1.821467	0.6141320	-2.965921	0.0030178	0.3337528	ENSG00000163734.4	CXCL3
92.01183	1.689547	0.5729651	2.948778	0.0031903	0.3348805	ENSG00000233101.6	HOXB-AS3
89.73450	1.895736	0.6439368	2.943979	0.0032402	0.3348805	ENSG00000170608.2	FOXA3
88.96362	1.585919	0.5421862	2.925046	0.0034441	0.3444376	ENSG00000133055.4	MYBPH
223.78773	2.073370	0.7104688	2.918312	0.0035193	0.3469592	ENSG00000248144.1	ADH1C
2221.34904	-2.334577	0.8016507	-2.912212	0.0035888	0.3476457	ENSG00000124882.3	EREG
270.24130	-1.566212	0.5395500	-2.902811	0.0036983	0.3519415	ENSG00000258399.2	MEG8
793.56540	1.755844	0.6066222	2.894460	0.0037981	0.3581407	ENSG00000131771.9	PPP1R1B
166.96954	1.891462	0.6546790	2.889144	0.0038629	0.3581407	ENSG00000104313.13	EYA1
412.30805	1.608811	0.5580713	2.882805	0.0039415	0.3600520	ENSG00000183250.7	C21orf67
427.19034	1.522498	0.5289549	2.878313	0.0039981	0.3600520	ENSG00000158089.10	GALNT14
127.23181	1.789325	0.6233850	2.870337	0.0041003	0.3645091	ENSG00000079112.5	CDH17
49.57855	1.557681	0.5436263	2.865352	0.0041655	0.3663806	ENSG00000141750.6	STAC2
175.21629	1.759546	0.6145590	2.863104	0.0041951	0.3663806	ENSG00000137869.9	CYP19A1
65.55430	1.829125	0.6393324	2.860993	0.0042232	0.3663806	ENSG00000145920.10	CPLX2
76.40419	1.784447	0.6279288	2.841799	0.0044860	0.3677171	ENSG00000272825.1	LL21NC02-1C16.2
328.06406	2.304766	0.8113053	2.840812	0.0044999	0.3677171	ENSG00000186081.7	KRT5
75.12625	1.864432	0.6644165	2.806119	0.0050142	0.3896298	ENSG00000182379.9	NXPH4
46.47827	1.510250	0.5405723	2.793799	0.0052093	0.3959636	ENSG00000162078.7	ZG16B
533.57693	-1.672252	0.5990182	-2.791654	0.0052439	0.3959636	ENSG00000166292.7	TMEM100
245.16153	1.885776	0.6757547	2.790621	0.0052607	0.3959636	ENSG00000227318.4	RP11-282E4.1
138.70116	1.679888	0.6033597	2.784223	0.0053656	0.4024580	ENSG00000253686.1	CTB-43E15.3
150.37725	2.141590	0.7701221	2.780845	0.0054218	0.4024728	ENSG00000211658.2	IGLV3-27
1638.38386	1.645987	0.5923558	2.778714	0.0054575	0.4024728	ENSG00000265735.1	RN7SL5P
365.60222	-1.895866	0.6852632	-2.766624	0.0056640	0.4038524	ENSG00000134020.6	PEBP4
72.35067	1.835890	0.6652252	2.759803	0.0057836	0.4038524	ENSG00000214814.2	FER1L6
308.72756	1.831146	0.6675133	2.743236	0.0060837	0.4096723	ENSG00000224041.2	IGKV3D-15
55.58674	-1.546631	0.5639979	-2.742264	0.0061017	0.4096723	ENSG00000255299.1	RP11-655C2.3
482.41423	1.667731	0.6126066	2.722352	0.0064819	0.4183471	ENSG00000198807.8	PAX9
80.77480	1.682582	0.6194499	2.716251	0.0066026	0.4184167	ENSG00000094755.12	GABRP
592.13139	-2.269389	0.8356776	-2.715628	0.0066150	0.4184167	ENSG00000188517.10	COL25A1
506.66321	1.796203	0.6621138	2.712832	0.0066711	0.4189215	ENSG00000240382.1	IGKV1-17
194.63498	1.666293	0.6148228	2.710200	0.0067243	0.4202647	ENSG00000166206.9	GABRB3
53.71918	1.525999	0.5635879	2.707650	0.0067762	0.4218401	ENSG00000145692.10	BHMT
103.49839	1.674500	0.6199147	2.701179	0.0069094	0.4251003	ENSG00000206172.4	HBA1
467.79707	-1.923180	0.7127854	-2.698119	0.0069732	0.4251003	ENSG00000115008.5	IL1A
209.26049	1.915283	0.7121944	2.689270	0.0071609	0.4261387	ENSG00000228991.2	RP11-318K12.1
113.24287	-1.787114	0.6658526	-2.683948	0.0072758	0.4261387	ENSG00000007314.7	SCN4A
134.68469	-2.035335	0.7609013	-2.674901	0.0074751	0.4331887	ENSG00000171243.7	SOSTDC1
341.34122	1.696462	0.6397603	2.651715	0.0080084	0.4422207	ENSG00000196754.6	S100A2
113.28906	1.611524	0.6118947	2.633661	0.0084470	0.4520798	ENSG00000243264.1	IGKV2D-29
335.21258	1.503002	0.5756579	2.610928	0.0090297	0.4666365	ENSG00000153930.6	ANKFN1
236.83536	1.697918	0.6505133	2.610120	0.0090510	0.4666365	ENSG00000071909.14	MYO3B
497.76560	1.609049	0.6199244	2.595556	0.0094438	0.4733293	ENSG00000182272.7	B4GALNT4
7169.29993	-2.041323	0.7876501	-2.591663	0.0095513	0.4748842	ENSG00000169429.6	IL8
1055.00488	1.671988	0.6469940	2.584240	0.0097594	0.4805724	ENSG00000007062.7	PROM1
134.26570	1.856328	0.7208032	2.575360	0.0100136	0.4866523	ENSG00000211655.2	IGLV1-36
1382.19972	1.589273	0.6173879	2.574189	0.0100475	0.4866523	ENSG00000244437.1	IGKV3-15
2371.63303	1.664484	0.6470234	2.572525	0.0100960	0.4871585	ENSG00000241351.1	IGKV3-11
64.94373	1.590553	0.6214376	2.559473	0.0104831	0.4978961	ENSG00000231980.1	AC011899.10
79.56897	1.648305	0.6457144	2.552684	0.0106897	0.4987430	ENSG00000262739.1	PRSS2
262.91121	1.537413	0.6055896	2.538704	0.0111264	0.5035765	ENSG00000165309.9	ARMC3
359.07544	1.660664	0.6545098	2.537263	0.0111723	0.5035765	ENSG00000108176.10	DNAJC12
237.48855	1.710380	0.6765425	2.528119	0.0114675	0.5094550	ENSG00000181449.2	SOX2
1125.66995	1.776563	0.7037285	2.524500	0.0115863	0.5094550	ENSG00000154277.8	UCHL1
503.75045	1.582075	0.6267031	2.524442	0.0115882	0.5094550	ENSG00000136231.9	IGF2BP3
133.54198	1.516342	0.6050108	2.506306	0.0122000	0.5157424	ENSG00000182230.7	FAM153B
356.53727	1.501117	0.6034918	2.487386	0.0128686	0.5221042	ENSG00000240864.1	IGKV1-16
118.84073	-1.599603	0.6441052	-2.483450	0.0130116	0.5221042	ENSG00000154165.3	GPR15
120.12455	-1.578267	0.6448029	-2.447673	0.0143782	0.5331409	ENSG00000072657.4	TRHDE
477.68986	2.030376	0.8297906	2.446853	0.0144109	0.5331409	ENSG00000230937.5	MIR205HG
387.43476	1.542451	0.6377843	2.418452	0.0155867	0.5492715	ENSG00000081277.7	PKP1
961.88912	1.507931	0.6292008	2.396582	0.0165488	0.5620864	ENSG00000140297.8	GCNT3
10084.19474	1.597810	0.6699393	2.385008	0.0170788	0.5675926	ENSG00000181143.11	MUC16
434.97477	1.668692	0.7106351	2.348169	0.0188659	0.5774524	ENSG00000160180.14	TFF3
311.28342	1.903082	0.8171730	2.328860	0.0198665	0.5831579	ENSG00000161896.6	IP6K3
4426.97509	-1.967797	0.8540918	-2.303964	0.0212247	0.5986949	ENSG00000096088.12	PGC
1614.95993	1.616223	0.7026279	2.300254	0.0214338	0.6014622	ENSG00000148346.7	LCN2
3993.95828	-2.021557	0.8795374	-2.298432	0.0215372	0.6018767	ENSG00000125538.7	IL1B
243.36916	1.760698	0.7662766	2.297732	0.0215771	0.6018767	ENSG00000100170.5	SLC5A1
279.59289	-1.574827	0.6862896	-2.294697	0.0217505	0.6026352	ENSG00000170323.4	FABP4
9865.29649	2.698572	1.1780155	2.290778	0.0219762	0.6026352	ENSG00000215182.6	MUC5AC
3711.83764	-1.979508	0.8708877	-2.272977	0.0230276	0.6066357	ENSG00000206450.6	HLA-B
88.33908	-1.534156	0.6761248	-2.269043	0.0232657	0.6075174	ENSG00000243197.3	TUSC7
109.75414	1.585905	0.7003008	2.264605	0.0235369	0.6092017	ENSG00000237111.1	IGHJ3P
2354.46471	-1.561942	0.6991038	-2.234206	0.0254695	0.6240623	ENSG00000211949.2	IGHV3-23
254.34041	1.687285	0.7620791	2.214055	0.0268250	0.6244321	ENSG00000211670.2	IGLV3-9
17735.93724	1.661772	0.7514571	2.211400	0.0270082	0.6253078	ENSG00000118785.9	SPP1
1160.03234	1.558448	0.7122619	2.188027	0.0286676	0.6332089	ENSG00000196611.4	MMP1
257.27103	1.850719	0.8569981	2.159537	0.0308085	0.6429202	ENSG00000186832.4	KRT16
2826.64461	1.637676	0.7634336	2.145145	0.0319412	0.6463859	ENSG00000187134.8	AKR1C1
1048.87579	1.689868	0.8070665	2.093841	0.0362742	0.6620110	ENSG00000166105.11	GLB1L3
313.04687	1.831229	0.9143476	2.002771	0.0452019	0.6905475	ENSG00000270398.1	IGHV3-7
368.63115	1.678044	0.8504424	1.973142	0.0484794	0.6936735	ENSG00000211939.2	IGHV1-8
324.57137	-1.670644	0.8512352	-1.962612	0.0496913	0.6975870	ENSG00000166961.10	MS4A15

Pathway enrichment analysis fGSEA

Indolent (n_op2 = ‘ind’) is the reference. When sample is Aggressive (‘agg’), pathways shown below are up- or down- regulated

• pathway – name of the pathway as in ‘names(pathway)’;

• pval – an enrichment p-value;

• padj – a BH-adjusted p-value;

• log2err – the expected error for the standard deviation of the P-value logarithm.

• ES – enrichment score, same as in Broad GSEA implementation;

• NES – enrichment score normalized to mean enrichment of random samples of the same size; • size – size of the pathway after removing genes not present in ‘names(stats)’.

• leadingEdge – vector with indexes of leading edge genes that drive the enrichment, see http://software.broadinstitute.org/gsea/doc/GSEAUserGuideTEXT.htm\#\_Running_a\_Leading.

## Warning in fgseaMultilevel(...): There were 1 pathways for which P-values were
## not calculated properly due to unbalanced (positive and negative) gene-level
## statistic values. For such pathways pval, padj, NES, log2err are set to NA. You
## can try to increase the value of the argument nPermSimple (for example set it
## nPermSimple = 10000)

## Warning in fgseaMultilevel(...): For some of the pathways the P-values were
## likely overestimated. For such pathways log2err is set to NA.

## Warning in fgseaMultilevel(...): There were 4 pathways for which P-values were
## not calculated properly due to unbalanced (positive and negative) gene-level
## statistic values. For such pathways pval, padj, NES, log2err are set to NA. You
## can try to increase the value of the argument nPermSimple (for example set it
## nPermSimple = 10000)

## Warning in fgseaMultilevel(...): For some of the pathways the P-values were
## likely overestimated. For such pathways log2err is set to NA.

## Warning in fgseaMultilevel(...): There were 42 pathways for which P-values were
## not calculated properly due to unbalanced (positive and negative) gene-level
## statistic values. For such pathways pval, padj, NES, log2err are set to NA. You
## can try to increase the value of the argument nPermSimple (for example set it
## nPermSimple = 10000)

## Warning in fgseaMultilevel(...): For some of the pathways the P-values were
## likely overestimated. For such pathways log2err is set to NA.

## Warning in fgseaMultilevel(...): There were 62 pathways for which P-values were
## not calculated properly due to unbalanced (positive and negative) gene-level
## statistic values. For such pathways pval, padj, NES, log2err are set to NA. You
## can try to increase the value of the argument nPermSimple (for example set it
## nPermSimple = 10000)

## Warning in fgseaMultilevel(...): For some of the pathways the P-values were
## likely overestimated. For such pathways log2err is set to NA.

## Warning in preparePathwaysAndStats(pathways, stats, minSize, maxSize, gseaParam, : There are ties in the preranked stats (0.01% of the list).
## The order of those tied genes will be arbitrary, which may produce unexpected results.

## Warning in fgseaMultilevel(...): There were 3 pathways for which P-values were
## not calculated properly due to unbalanced (positive and negative) gene-level
## statistic values. For such pathways pval, padj, NES, log2err are set to NA. You
## can try to increase the value of the argument nPermSimple (for example set it
## nPermSimple = 10000)

## Warning in fgseaMultilevel(...): For some of the pathways the P-values were
## likely overestimated. For such pathways log2err is set to NA.

Hallmark Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.0000000	0.0000000	1.3188888	-0.5693712	-3.075804	189	CXCL3 IL1A OLR1 DENND5A IL1B PTPRE BMP2 SIK1 EGR2 CD44 CCRL2 FOSL1 BCL2A1 TRIB1 IL23A IER2 CCNL1 ATP2B1 CLCF1 HBEGF EIF1 BTG2 MAP3K8 LITAF KLF10 KLF6 PTX3 NR4A1 NFE2L2 BTG3 MCL1 TIPARP RHOB MAP2K3 STAT5A BIRC2 KLF4 PLAUR KLF9 DRAM1 NFKB1 CDKN1A CXCL2 ATF3 ID2 CCL4 PNRC1 PER1 DUSP1 PLEK INHBA IL7R HES1 MAFF SNN BTG1 NINJ1 CD80 AREG IL6 SGK1 SOCS3 SERPINB8 JUN JUNB RCAN1 PPP1R15A PTGER4 ACKR3 CD83 GPR183 REL TNFRSF9 GFPT2 FOS KLF2 FOSB EHD1 TGIF1 TSC22D1 DUSP5 IRS2 SOD2 KYNU PDE4B ETS2 CCL20 GEM ICAM1 IL18 PDLIM5 TNFAIP8 IER5 CEBPD RIPK2 TRAF1 NFKBIA EDN1 TNFSF9 LDLR SPHK1 CSF2 SPSB1 EGR1 SERPINE1 FJX1 NR4A2 ZFP36 YRDC DNAJB4 CD69	down	***
HALLMARK_E2F_TARGETS	0.0000000	0.0000000	0.9865463	0.5287633	2.419501	182	TRIP13 HELLS CHEK2 BUB1B NUP107 TIMELESS UBE2T KIF18B PRIM2 DEPDC1 TBRG4 BRCA1 GINS1 CDK4 RACGAP1 E2F8 POLE PLK1 CDCA8 AURKB PTTG1 ESPL1 CCNB2 MCM4 MCM2 CDC25A MYBL2 PMS2 GINS4 NCAPD2 WDR90 NME1 RANBP1 MELK HMMR MKI67 TOP2A AURKA POLA2 POLD2 KIF2C MCM7 RRM2 MMS22L PRKDC MCM3 LMNB1 LIG1 CHEK1 ORC6 MAD2L1 RAD51AP1 DCTPP1 SPC24 DSCC1 CKS1B CDKN2C CBX5 ASF1B CDK1 BIRC5 UNG EZH2 NUP205 SPAG5 DIAPH3 PA2G4 RNASEH2A DNMT1 CCNE1 TUBG1 DLGAP5 TACC3 KIF22 SSRP1 TK1 ANP32E POLD1 RAD50 CDC20 CENPM PPP1R8 HMGA1 POP7 RPA1 MCM6 MCM5 SRSF1 GINS3	up	***
HALLMARK_TGF_BETA_SIGNALING	0.0000007	0.0000058	0.6594444	-0.5419986	-2.353201	52	SMAD6 BMP2 ENG BMPR2 RHOA KLF10 SPTBN1 UBE2D3 ID3 TJP1 THBS1 CDK9 ID2 SMAD7 BCAR3 RAB31 LTBP2 JUNB PPP1R15A SKIL TGFB1 TGIF1 FKBP1A CDKN1C SKI SERPINE1 NOG	down	***
HALLMARK_GLYCOLYSIS	0.0000000	0.0000000	0.9436322	0.5140026	2.347535	172	GPR87 KIF20A BIK EGLN3 PKP2 AK4 CHST6 PPFIA4 DDIT4 CHST4 DEPDC1 TFF3 GAL3ST1 B3GAT1 EFNA3 ANKZF1 CENPA SOX9 STC2 DPYSL4 COPB2 B4GALT4 HMMR GFPT1 TPBG AURKA PKM ANG FAM162A EGFR B3GNT3 ABCB6 PFKP B4GALT7 GNPDA1 NOL3 ALDOA CLDN9 SLC25A10 CASP6 PLOD2 CDK1 MERTK GOT2 RBCK1 POLR3K ALDOB SLC25A13 KIF2A ARTN PSMC4 MPI GALK2 AGL ALDH7A1 XYLT2 COG2 SLC37A4 SRD5A3 SAP30 CHPF P4HA1 TSTA3 KDELR3 GMPPA MED24 SLC35A3 HAX1 LHPP SPAG4 ME1 HDLBP HK2 ZNF292 PAXIP1 PGAM1 CHPF2 GNE ALG1 BPNT1 IDUA PPIA ENO1	up	***
HALLMARK_G2M_CHECKPOINT	0.0000000	0.0000000	0.9101197	0.5013057	2.294506	181	CDC45 TROAP NEK2 CENPF POLQ PBK NDC80 PRIM2 TTK CDK4 RACGAP1 TRAIP POLE STIL PLK1 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 E2F3 CCNB2 MCM2 CDC25A MYBL2 PRC1 EFNA5 CCNF LIG3 HMMR EXO1 SMARCC1 KIF23 CHAF1A MKI67 KIF15 BUB1 TOP2A AURKA ODF2 POLA2 KIF2C E2F2 RAD54L KIF11 MCM3 LMNB1 CHEK1 ORC6 MAD2L1 PML MNAT1 INCENP CKS1B CDKN2C NUSAP1 CDK1 UCK2 BIRC5 E2F1 EZH2 TNPO2 EGF CBX1 KPNB1 TACC3 KIF22 HIRA DTYMK GINS2 KIF20B SAP30 CDC7 CDC20 HMGA1 MCM6 MCM5 SNRPD1 SRSF1	up	***
HALLMARK_INFLAMMATORY_RESPONSE	0.0000000	0.0000000	0.7749390	-0.3958716	-2.133027	179	SLC31A2 EREG IL1A OLR1 CD55 IL1B PTPRE CCRL2 CALCRL AQP9 C5AR1 MARCO SCARF1 ATP2B1 HBEGF SGMS2 BEST1 ITGA5 BTG2 RNF144B NMUR1 KLF6 IL18R1 SLC7A2 IL10 MSR1 PTGIR CCL22 MEFV PTAFR PLAUR TNFSF15 NFKB1 CDKN1A P2RY2 IRAK2 SELL AXL INHBA IL7R PIK3R5 EMP3 IL6 PSEN1 IL2RB CD48 HRH1 RHOG PTGER4 CCR7 GPR183 OSM PTGER2 TNFRSF9 IFNAR1 KCNA3 PDE4B CCL20 ICAM1 IL18 IL18RAP SLC31A1 RIPK2 NLRP3 NFKBIA EDN1 TNFSF9 KIF1B LDLR SPHK1 ABI1 CD70 SERPINE1	down	***
HALLMARK_APOPTOSIS	0.0000141	0.0001008	0.5933255	-0.3572016	-1.848493	144	WEE1 EREG SC5D IL1A HMOX1 IL1B BMP2 CD44 CAV1 TGFBR3 NEDD9 CASP9 TXNIP ANXA1 DNAJC3 LMNA BTG2 HSPB1 BTG3 MCL1 DIABLO RHOB PPT1 CASP1 ROCK1 CDKN1A ATF3 CCND2 PRF1 SMAD7 ADD1 TGFB2 ETF1 IL6 PSEN1 JUN DNAJA1 IFNGR1 TIMP2 PEA15 PPP3R1 SOD2 LGALS3 TSPO BNIP3L GPX3 IL18	down	***
HALLMARK_MYC_TARGETS_V2	0.0004322	0.0018007	0.4984931	0.4797384	1.827118	56	SORD TBRG4 CDK4 PLK1 MCM4 CBX3 SLC29A2 AIMP2 DCTPP1 PHB PES1 UNG NOP2 PA2G4 PUS1 MYBBP1A RRP9 UTP20 MCM5 NOC4L RABEPK EXOSC5 FARSA HK2 MRTO4 SRM PLK4 NPM1 IMP4	up	**
HALLMARK_KRAS_SIGNALING_UP	0.0000642	0.0004014	0.5384341	-0.3178335	-1.686349	170	RBP4 SLPI EREG TMEM100 ACE PECAM1 USP12 IL1B PRKG2 BMP2 ENG MTMR10 FUCA1 CBL EPB41L3 TRIB1 ABCB1 APOD SEMA3B HBEGF ADAM17 MALL LCP1 RBM4 SPRY2 CD37 CDADC1 KLF4 PLAUR PEG3 LY96 LAPTM5 ID2 CCND2 FCER1G CCSER2 INHBA IL7R	down	***
HALLMARK_ALLOGRAFT_REJECTION	0.0000986	0.0004930	0.5384341	-0.3196450	-1.683953	156	EREG IL1B GPR65 LY86 IGSF6 CD8A FGR CRTAM SRGN SPI1 IL10 CCL22 SOCS5 PTPRC CCL4 CCND2 PRF1 INHBA KLRD1 HLA-DQA1 DEGS1 TGFB2 CD8B CD80 IL6 CTSS IL2RB STAT4 ETS1 IFNGR1 RPL9 IRF8 CD7 PRKCG CD74 TGFB1 CD1D APBB1 CD86 CCR1 ICAM1 IL18 IL18RAP RIPK2 NLRP3 UBE2D1 BCAT1 CD3G CCND3 IL16 ABI1 ITGAL UBE2N BCL10 CD3E TRAT1 IRF4 CD4 GZMB EIF3J CAPG CDKN2A ABCE1 CD47 FASLG GZMA B2M ITK HCLS1 CD3D CCR5 GALNT1 IFNG JAK2 TLR3	down	***
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.0034125	0.0093558	0.4317077	-0.3670355	-1.676312	67	SC5D CXCL16 PPARG CPEB2 LPL IDI1 HMGCR CD9 STARD4 SEMA3B ANXA5 FABP5 PLAUR ATF3 PNRC1	down	**
HALLMARK_COMPLEMENT	0.0000727	0.0004041	0.5384341	-0.3167738	-1.675033	168	FCN1 OLR1 CD55 LTA4H LIPA PCSK9 FYN CDH13 CASP9 CD36 TMPRSS6 PLA2G7 SH2B3 CSRP1 GNGT2 ANXA5 GATA3 ZEB1 APOC1 CASP5 CASP1 PLAUR CTSD DOCK9 FCER1G PLEK GCA PIK3R5 GNAI2 C4BPB MAFF USP16 PRCP IL6 CTSS PSEN1 C1QA RHOG GRB2 CALM1 DGKG CR1 PPP2CB TIMP2 EHD1 DUSP5 MMP15 PIM1 GNB4 LGALS3 KYNU ACTN2 SPOCK2 CPQ FDX1 CTSC DOCK10 DOCK4 ZFPM2 HPCAL4 IRF2 SERPINE1 CTSH DUSP6	down	***
HALLMARK_ESTROGEN_RESPONSE_LATE	0.0002532	0.0011510	0.4984931	0.3657668	1.668485	174	LTF TFPI2 PRLR PTGES KIF20A KCNK5 DNAJC12 FRK SORD TFF3 SLC27A2 STIL CDC6 RBBP8 AGR2 LSR CA12 CYP4F11 TJP3 LAMC2 TRIM29 TPBG TOP2A GPER1 SERPINA3 MDK SLC9A3R1 ASS1 PERP TST FLNB IDH2 DLG5 CXCL14 RAPGEFL1 GJB3 METTL3 ETFB FAM102A RNASEH2A HSPA4L ST14 SLC26A2 LLGL2 PKP3 MAPK13 SLC22A5 S100A9 CPE GINS2 KRT19	up	**
HALLMARK_IL6_JAK_STAT3_SIGNALING	0.0029345	0.0090632	0.4317077	-0.3575525	-1.658480	73	CXCL3 ACVRL1 IL17RB HMOX1 IL1B CD44 MYD88 CD9 CBL CD36 MAP3K8 IL18R1 PIK3R5 IL6 SOCS3 JUN IFNGR1 GRB2 TGFB1 IFNAR1 PIM1 CCR1	down	**
HALLMARK_SPERMATOGENESIS	0.0024321	0.0081070	0.4317077	0.3990646	1.644713	87	NEK2 COIL CLGN TTK CCNB2 SCG5 MAP7 RPL39L BUB1 AURKA GPR182 KIF2C TEKT2 PHKG2 OAZ3 TOPBP1 CDK1 EZH2 HSPA4L NPHP1 MTOR PCSK4 IL12RB2 GAD1 NEFH STRBP SLC2A5 YBX2 LPIN1 NOS1 MEP1B VDAC3 SLC12A2 ALOX15 NCAPH PARP2	up	**
HALLMARK_KRAS_SIGNALING_DN	0.0019487	0.0069598	0.4550599	0.3726760	1.602090	114	RIBC2 HNF1A SLC5A5 KRT5 TG PKP1 CHRNG TENM2 SLC6A3 KLHDC8A KRT15 CLSTN3 STAG3 ZNF112 IFI44L IL12B TGM1 SIDT1 EDN2 FGGY MYOT EGF NRIP2 GPRC5C SPTBN2 DLK2 THRB NR6A1 TFCP2L1 PRODH EDAR CLDN16 YBX2 DTNB NOS1 GTF3C5 CELSR2 ENTPD7 MYO15A IDUA COPZ2 CAPN9 CDKAL1 GP1BA HSD11B2	up	**
HALLMARK_P53_PATHWAY	0.0017070	0.0065653	0.4550599	-0.2798668	-1.512716	182	IL1A HMOX1 PTPRE BMP2 BAIAP2 CDH13 FUCA1 PPM1D RCHY1 TXNIP HBEGF ADA GM2A BTG2 IFI30 SLC7A11 STOM RB1 ZNF365 PDGFA CASP1 KLF4 DRAM1 CEBPA CTSD PMM1 CDKN1A RRP8 ATF3 CCND2 DNTTIP2 CDKN2AIP PROCR BTG1 NINJ1 JUN NOTCH1 PLK3 AK1 PPP1R15A NUDT15 SLC3A2 FOS FOXO3 TGFB1 CCP110 OSGIN1 TSC22D1 CD81 TOB1 RXRA SESN1 CGRRF1 IER5 EPHA2 ISCU S100A4	down	**
HALLMARK_MITOTIC_SPINDLE	0.0035552	0.0093558	0.4317077	0.3268023	1.499693	187	CEP72 NEK2 CENPF NDC80 PIF1 TTK RACGAP1 ANLN PLK1 ECT2 ESPL1 TPX2 CCNB2 PRC1 CEP250 DLG1 KIF23 KIF15 KNTC1 WASF1 KIF3B BUB1 TOP2A AURKA KIF2C CD2AP KIF11 LMNB1 CDC42EP1 KIF3C FLNB GEMIN4 INCENP NUSAP1 CDK1 CENPJ BIRC5 DYNLL2 NF1 RAPGEF5 NET1 CEP192 DLGAP5 TRIO KIF22 KIF20B SASS6 CKAP5 CDK5RAP2 KPTN KATNB1 MARCKS ALMS1 CYTH2 CDC42BPA ARHGAP5 MARK4 LLGL1 RHOT2 CTTN CENPE	up	**
HALLMARK_UV_RESPONSE_DN	0.0030815	0.0090632	0.4317077	-0.2883899	-1.480131	135	DLC1 PPARG INSIG1 BDNF FYN CAV1 CITED2 DYRK1A NR3C1 TGFBR3 TGFBR2 ATP2B1 PTPRM AKT3 ZMIZ1 PTPN21 KCNMA1 DAB2 TJP1 GRK5 NFKB1 NR1D2 DUSP1 SMAD7 NEK7 MAGI2 APBB2 PRKCE CELF2 SPOP PHF3 ATXN1 LTBP1 RXRA PDLIM5 TFPI KIT PTEN LDLR YTHDC1 KALRN CDON SERPINE1 PEX14 CDKN1B	down	**
HALLMARK_IL2_STAT5_SIGNALING	0.0048147	0.0120366	0.4070179	-0.2692602	-1.455386	182	SWAP70 DENND5A GLIPR2 LRRC8C GPR65 BMP2 CD44 BMPR2 SLC39A8 IL1RL1 ABCB1 TNFRSF8 MAP3K8 KLF6 IL18R1 RHOB IL10 AHNAK SOCS2 ITIH5 SELL SELP HOPX SHE CCND2 ARL4A MAFF PTH1R MYO1C PHTF2 IL2RB CD48 CTSZ IFNGR1 GSTO1 CD83 IRF8 PTGER2 SERPINB6 TNFRSF9 CST7 SNX9 SPRY4 CCR4 CD86 PIM1 CD81 GABARAPL1 SYT11 TIAM1 CDKN1C ITGAE PTCH1 TRAF1 FAM126B RORA CCND3 RNH1 CSF2 PRKCH ICOS CD79B SNX14 NFIL3 ITGA6 IRF4 TTC39B CASP3 NFKBIZ GALM EMP1 PNP ADAM19 TNFRSF1B F2RL2 IL10RA CAPG	down	*

C1 positional genes Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
chr7p22	0.0000000	0.0000000	0.9759947	0.6772099	2.658854	71	C1GALT1 SLC29A4 ZDHHC4 ZNF12 IQCE ANKRD61 PMS2CL PMS2 EIF3B INTS1 FAM220A MICALL2 NUDT1 CARD11 RNF216P1 BRAT1 TMEM184A GPER1 MAD1L1 RNF216-IT1 WIPI2 SDK1 EIF2AK1 GPR146 AIMP2 KDELR2 GET4 C7orf50 COX19 CYP2W1 TTYH3 C7orf26 RBAK RNF216 SUN1 ADAP1 GRID2IP ZNF815P AP5Z1 PSMG3 USP42 TNRC18 RN7SKP130 FOXK1 CCZ1B	up	***
chr12q14	0.0000004	0.0000166	0.6749629	0.6385243	2.258548	41	HMGA2 GRIP1 GAPDHP44 PPM1H LRIG3 KLF17P1 AVIL TSFM C12orf66 METTL1 CDK4 CYP27B1 CAND1 XPOT HELB CTDSP2 TSPAN31	up	***
chr4q21	0.0000014	0.0000490	0.6435518	-0.5074576	-2.256277	60	MRPS18C PRKG2 NUP54 COQ2 THAP9-AS1 RCHY1 NAAA PAQR3 HNRNPDL CCNI HPSE AFF1 ANXA3 SEC31A COPS4 CNOT6L RASGEF1B LIN54 TECRP1 USO1 BMP3 HELQ HNRNPD C4orf36 THAP9 SLC10A6 PRDM8 BMP2K MRPL1 THAP6 G3BP2 SDAD1	down	***
chr8p22	0.0000650	0.0011246	0.5384341	-0.6987969	-2.242440	18	DLC1 ASAH1 ZDHHC2 SLC7A2 MSR1 RPL35P6 VPS37A RNA5SP256 MIR548V CNOT7 MICU3 PCM1 MTUS1	down	**
chr5p15	0.0000017	0.0000521	0.6435518	0.5834490	2.189655	53	SLC9A3 TRIP13 CEP72 PDCD6 CCDC127 SDHAP3 NDUFS6 PLEKHG4B SLC6A3 EXOC3 CLPTM1L MIR4458HG SDHA CCT5 MYO10 NSUN2 CMBL SLC12A7 BRD9 MRPL36 DNAH5 DAP SRD5A1 SNHG18 TRIO	up	***
chr12q15	0.0000022	0.0000624	0.6272567	0.7071863	2.188789	24	KRT8P39 MDM1 NUP107 CPSF6 RAB3IP PTPRR YEATS4 SLC35E3 KCNMB4 CCT2 FRS2 MYRFL MDM2 DYRK2 CNOT2 HNRNPA1P70 IFNG-AS1	up	***
chr22q11	0.0000000	0.0000002	0.7881868	0.4943894	2.171155	140	IGLV4-69 ZDHHC8P1 POM121L9P IGLV3-27 CDC45 CECR7 DGCR5 IGLV1-36 ZNF280B DGCR9 CABIN1 IGLV3-9 DGCR8 IGLC7 KRT18P5 RAB36 TOP3B RANBP1 IGLV3-10 ZNF74 DDTL IGLV1-44 SLC2A11 PEX26 TRMT2A IGLV1-40 PPIL2 PI4KAP1 GNB1L RN7SL812P LINC00896 DDT KLHL22 IGLV7-43 LZTR1 DGCR6 TBX1 IGLV6-57 GGT2 YDJC C22orf15 SLC25A18 HIRA TUBA8 IGLV1-47 GNAZ RGL4 USP18 DGCR11 ARVCF GGT3P PRODH GGT5 PI4KA IGLL5 PI4KAP2 MICAL3 ZNF70 SERPIND1	up	***
chr13q14	0.0000002	0.0000089	0.6901325	-0.4249074	-2.131468	112	MED4-AS1 THSD1 MED4 RLIMP1 SLC25A30 RN7SL413P WBP4 PCNPP5 FAM124A SERP2 PPP1R26P1 LCP1 RB1 RGCC RNU2-6P ARL11 CDADC1 FOXO1 ITM2B SPRYD7 KPNA3 LACC1 ELF1 ESD LRCH1 SUGT1P3 NUDT15 DLEU2 RGS17P1 RAD17P2 NAA16 OGFOD1P1 TSC22D1 LINC00562 PHF11 RNU6-60P INTS6 SNORA31 SETDB2 TPT1 DHRS12 NEK3 GTF2F2 LPAR6 RPL18P10 GPALPP1 SUGT1 RN7SL288P LRRC63 RNU6-57P VPS36 TRIM13 RCBTB2 FNDC3A MRPS31P5 WDFY2 MIR621 RNY3P2	down	***
chr13q34	0.0001150	0.0015059	0.5384341	-0.5294106	-2.107594	39	GAS6 LAMP1 COL4A2-AS2 ATP11A-AS1 ANKRD10 TMEM255B ANKRD10-IT1 RNU1-16P CARS2 LINC00346 CUL4A ATP11A TEX29 GAS6-AS1 TUBGCP3 IRS2 CDC16 DCUN1D2-AS DCUN1D2 ING1 COL4A2-AS1 PCID2 COL4A2	down	**
chr13q32	0.0001294	0.0015264	0.5188481	-0.5432502	-2.098449	35	STK24-AS1 CLYBL DNAJC3 UBAC2-AS1 RNA5SP37 ABCC4 DOCK9 TM9SF2 STK24 MTCYBP3 MTND5P2 DOCK9-AS1 UBAC2 MBNL2 GPR183 GPR18 PCCA IPO5	down	**
chr7q22	0.0000000	0.0000028	0.7195128	0.4808257	2.067051	125	SLC26A4 MYH16 AGFG2 AP1S1 SPDYE6 BAIAP2L1 GPC2 ZNF3 CYP3A5 SPDYE3 STAG3 DPY19L2P2 AP4M1 PUS7 MCM7 TFR2 TRRAP PPP1R35 ZNHIT1 ZKSCAN1 CLDN15 ARPC1A ZSCAN25 SPDYE2 ZNF789 TAF6 NAPEPLD ZKSCAN5 GAL3ST4 GIGYF1 ZSCAN21 LRWD1 FAM200A COPS6 CPSF4 EFCAB10 POP7 ALKBH4 COL26A1 POLR2J SRRT TRIM56 SRPK2 LRRC17 POLR2J3 LRCH4 RASA4DP DUS4L RASA4B PMS2P1 COG5 EIF4BP6 PDAP1 TRIP6 RNU6-1322P FIS1 SPDYE2B EPHB4 FAM185A ARMC10 RASA4 AZGP1 NPTX2 CNPY4 TSC22D4 PCOLCE-AS1 CYP3A7 PLOD3 ORC5 SLC12A9 LAMTOR4 MUC12 KPNA7 DNAJC2 MOSPD3 PCOLCE TRIM4 STAG3L5P RWDD4P1 PMPCB PSMC2	up	***
chr8p21	0.0000058	0.0001375	0.6105269	-0.4411177	-2.055105	77	PEBP4 PDLIM2 PHYHIP DPYSL2 KCTD9 LPL C8orf58 SCARA3 BMP1 PPP2R2A SLC25A37 ATP6V1B2 PPP3CC SORBS3 SDAD1P1 GNRH1 EBF2 HMBOX1 PNMA2 RHOBTB2 ADRA1A ENTPD4 TNFRSF10B SFTPC DOK2 SCARA5 BNIP3L GULOP TNFRSF10D INTS10	down	***
chr4q24	0.0005429	0.0051383	0.4772708	-0.5494883	-2.032448	29	EMCN SLC39A8 MANBA TET2 TET2-AS1 PPP3CA UBE2D3 NPNT NFKB1 CXXC4 SLC9B1 PPA2 LRRC37A15P	down	**
chr3p13	0.0005930	0.0053872	0.4772708	-0.6347381	-2.010475	17	RN7SL418P FOXP1 RNU2-64P LINC00877 MIR1284 RYBP FOXP1-IT1 MITF	down	**
chr17q21	0.0000000	0.0000018	0.7337620	0.4285755	1.981097	212	HOXB-AS3 MYCBPAP EPN3 HOXB6 KIF18B TTC25 BRCA1 PRR15L DBF4B UBE2Z SNF8 KRT16 CDC6 NBR2 HOXB7 RUNDC3A CDK5RAP3 KRT15 GSDMB NME1 RND2 TOP2A EME1 FAM171A2 CACNA1G COASY CHAD MRPL27 ACSF2 ASB16 SLC25A39 LRRC37A4P PHB HOXB5 MEOX1 OSBPL7 NSF ZNF652 RAPGEFL1 LRRC37A2 CBX1 ITGA2B DNAJC7 KANSL1-AS1 KPNB1 EFTUD2 MAP3K14-AS1 G6PC3 PLEKHM1 COL1A1 TUBG1 DCAKD COA3 AARSD1 XYLT2 NGFR ACBD4 LRRC37A17P TAC4 SPATA32 RPS7P11 KRT19 ETV4 NAGS LINC00910 VPS25 TUBG2 TNS4 LRRC59 ACLY ABCC3 MED24 DHX8 SNX11 SKAP1 TTLL6 LRRC46 GOSR2 NME1-NME2 MAP3K14 ARL17B NBR1 RSAD1 RUNDC1 MRPS21P9 HOXB2 TMEM101 NMT1 DND1P1 COPZ2 UBTF KRT17 SPATA20 KRT8P34 KCNH4 HEXIM2 LUC7L3 MBTD1 SCRN2 ASB16-AS1 PDK2 SP6 UTP18 PNPO NFE2L1 GJD3	up	***
chr4q22	0.0006092	0.0053872	0.4772708	-0.5423594	-1.964011	27	HSD17B11 MMRN1 KLHL8 NUDT9 ABCG2 HERC3 PPM1K TMSB4XP8 HSD17B13 HPGDS GPRIN3 PKD2 NAP1L5 PDLIM5 SPARCL1	down	**
chr18q21	0.0001214	0.0015059	0.5384341	-0.4373352	-1.944496	60	C18orf32 TXNL1 NEDD4L ZCCHC2 KDSR ELAC1 SMAD7 MBD2 RPL17 HAUS1 PSTPIP2 MALT1 MAPK4 DYM WDR7 MRPL37P1 TCF4 CCDC68 CTIF ME2 SMAD2 VPS4B MEX3C SMAD4 PMAIP1 EPG5 ZBTB7C PIAS2 IER3IP1 POLI	down	**
chr7q34	0.0002605	0.0028351	0.4984931	0.5550178	1.937017	38	ATP6V0A4 PRSS2 RN7SL481P TTC26 AGK CASP2 RAB19 TRPV6 SLC37A3 TMEM178B SSBP1 MKRN1 UBN2 GSTK1 KIAA1549 MRPS33 TAS2R3 RN7SL535P ADCK2 ZC3HAV1L	up	**
chr11q23	0.0000755	0.0011246	0.5384341	-0.4069506	-1.908815	78	SIDT2 SC5D DDX6 PAFAH1B2 FXYD2 DSCAML1 CBL RBM7 RN7SKP273 PTS TREH USP2 CADM1 SIK2 BACE1 TECTA RNY4P6 SCN4B MPZL3 SDHD MCAM FXYD6 TAGLN IL18 SIK3 DIXDC1 TBCEL CD3G COLCA2 ZBTB16 RNF214 ARHGEF12 CD3E	down	**
chr3q21	0.0000332	0.0006709	0.5573322	0.4823727	1.906359	74	FAM86JP MUC13 RUVBL1 KBTBD12 CHCHD6 ALDH1L1 IFT122 CCDC14 ACAD9 MCM2 UMPS PODXL2 ALG1L COPG1 RPL32P3 EFCAB12 CCDC58 SEC61A1 FAM162A PLXNA1 EEFSEC MGLL DUTP1 WDR5B SNX4 SLC12A8 SNORA7B KIAA1257 MBD4 PARP9 ROPN1B RCC2P4 PARP14 HMCES SLC41A3 DTX3L	up	***
chr2q22	0.0033970	0.0203905	0.4317077	-0.6852515	-1.895194	11	ZEB2-AS1 ZEB2 GTDC1 THSD7B KYNU CXCR4 SPOPL	down	*
chr2p14	0.0029303	0.0188473	0.4317077	-0.5707398	-1.894823	20	PLEK CNRIP1 ACTR2 SERTAD2 RNU6-100P PNO1 MEIS1-AS2 PELI1 PPP3R1 MEIS1 AFTPH RAB1A CEP68	down	*
chr13q33	0.0018258	0.0129178	0.4550599	-0.5978569	-1.893657	17	FGF14-AS2 TPP2 ABHD13 TEX30 FGF14-IT1 NALCN EFNB2 ARGLU1 BIVM LIG4 FAM155A-IT1 ERCC5 FGF14 MYO16	down	*
chr7q36	0.0000605	0.0011246	0.5573322	0.4693010	1.881182	81	MNX1 PTPRN2 LINC00689 XRCC2 AOC1 NUB1 KCNH2 ZNF862 SMARCD3 SSPO WDR60 ZNF786 ZBED6CL LRRC61 REPIN1 NCAPG2 FASTK ATP6V0E2-AS1 ACTR3C PAXIP1-AS1 KRBA1 EZH2 ZNF775 ACTR3B WDR86 ATP6V0E2 YBX1P4 ATG9B SLC4A2 ZNF282 RBM33 ZNF783 TMUB1 PDIA4 ZNF212 ABCF2 VIPR2 PAXIP1 CDK5 TMEM176A CHPF2	up	**
chr17q23	0.0003864	0.0039055	0.4984931	-0.4431502	-1.868635	50	TUBD1 SCN4A ACE PECAM1 NDUFB8P2 PPM1D TEX2 TBX2 C17orf82 TBX4 RNFT1	down	**
chr17q12	0.0001085	0.0015059	0.5384341	0.4900154	1.866370	61	PPP1R1B STAC2 SLFN13 CCL8 GRB7 LIG3 NLE1 SLFN5 TADA2A TBC1D3 CDK12 C17orf78 SRCIN1 MYO19 RAD51D PSMB3 HNF1B SLFN12 HMGB1P24 AATF CISD3 MIEN1 MLLT6 ERBB2 SYNRG DDX52 SLFN12L CCL13 LASP1 PCGF2 RFFL AP2B1 PGAP3 CACNB1	up	**
chr5q34	0.0010428	0.0084322	0.4550599	0.7682150	1.847700	9	ATP10B TENM2 HMMR WWC1 GABRB2 CCNG1	up	**
chr7p13	0.0014583	0.0108607	0.4550599	0.5417125	1.834292	33	NPC1L1 COA1 NUDCD3 TBRG4 TUBG1P SPDYE1 POLM POLD2 YKT6 DDX56 CCM2 ZMIZ2 SNORA5C URGCP	up	*
chr11q12	0.0001224	0.0015059	0.5188481	-0.3709899	-1.832066	100	MS4A7 RN7SL23P LPXN WDR74 MS4A15 TMEM138 SLC15A3 CD5 BEST1 MS4A14 CYB561A3 MED19 MS4A1 LRRN4CL SNHG1 AHNAK MPEG1 STX3 HNRNPUL2 BTBD18 CNTF NXF1 ZFP91 STX5 SLC3A2 DAGLA FABP5P7 CD6 SNORA57 MS4A4A TMEM109 TMX2 ZDHHC5 MS4A2 SDHAF2 FADS3	down	**
chr11q21	0.0034585	0.0203905	0.4317077	-0.5151155	-1.831331	25	SLC36A4 AMOTL1 CCDC82 CEP57 FAM76B MAML2 SNORA1 MTMR2 ANKRD49 MED17 ENDOD1 C11orf54 TAF1D SCARNA9	down	*
chr1q21	0.0000216	0.0004712	0.5756103	0.4154316	1.827727	142	GPR89A DCST1 LYSMD1 S100A2 THEM4 CREB3L4 THEM5 EFNA3 FLAD1 EFNA4 NBPF20 DCST2 TDRKH C2CD4D GOLPH3L HRNR SEMA6C FLG SETDB1 UBE2Q1-AS1 HORMAD1 TARS2 NUDT17 OAZ3 POLR3C PSMD4 RAB13 CKS1B ACP6 VPS72 PIAS3 ZNF687 ILF2 SNX27 S100A16 UBE2Q1 ADAR S100A9 ANP32E NBPF10 S100A13 FLG-AS1 JTB ZBTB7B ANXA9 C1orf56 PYGO2 HAX1 PIP5K1A PSMB4 BCL9 NBPF14 NBPF18P SCNM1 CCT8P1 MRPL9 RPRD2 UBAP2L ADAM15 CGN PRPF3 RORC SLC39A1 PI4KB NBPF9 POGZ MLLT11	up	***
chr20q13	0.0000030	0.0000759	0.6272567	0.3985099	1.819604	192	WFDC10B PTPRT SPATA25 WFDC3 SLC13A3 RBBP8NL ZMYND8 EYA2 WFDC2 RN7SKP184 TSHZ2 HNRNPA1P3 L3MBTL1 BCAS1 TOMM34 ACOT8 MYBL2 SGK2 LIME1 ZFP64 NEURL2 OSBPL2 CYP24A1 C20orf197 WFDC13 AURKA SLC2A10 SYCP2 GNAS-AS1 PLTP FAM209A SAMD10 MIR941-2 ZNF512B ABHD16B DNTTIP1 DIDO1 BCAS4 PRPF6 UCKL1 GDAP1L1 IFT52 SNX21 TPD52L2 ZGPAT ARFRP1 PABPC1L SLC35C2 MRGBP ADNP ATP9A SALL4 SPINT4 ZSWIM3 ZSWIM1 CABLES2 TCEA2 LSM14B KCNB1 MIR941-1 PPP1R3D FITM2 GID8 RTEL1-TNFRSF6B STMN3 OGFR ARFGAP1 RTEL1 ZNF217 ADRM1 PFDN4 UBE2C TAF4 NPEPL1 ZNF831 ZBP1 MTG2 SS18L1 PMEPA1 CSTF1	up	***
chr3q22	0.0007135	0.0061188	0.4772708	0.4645587	1.782007	63	CPNE4 TF CEP70 FAM86HP TMCC1-AS1 TMCC1 EPHB1 PCCB IL20RB MRPL3 NME9 SLC35G2 TOPBP1 NEK11 ALG1L2 RAB6B SNORA58 CEP63 KY NUDT16	up	**
chr3p22	0.0003560	0.0037313	0.4984931	-0.3698082	-1.760283	89	TRIM71 STAC VIPR1-AS1 SEC22C MYD88 UBE2FP1 SCN5A LRRFIP2 EPM2AIP1 EIF1B CSRNP1 RPL21P135 MYRIP SS18L2 WDR48 OXSR1 PLCD1 TPMTP2 CMTM6 GLB1 NDUFAF4P3 PDCD6IP UBE2D3P2 TMPPE SNRK CCR4 ITGA9 RN7SL517P DYNC1LI1 CLASP2 XIRP1 CNOT10-AS1 TTC21A GPD1L DDTP1 EXOG CRTAP SLC25A38 CX3CR1	down	**
chr2p22	0.0025329	0.0170667	0.4317077	-0.4167086	-1.752917	48	GPATCH11 NLRC4 HEATR5B SRSF7 NDUFAF7 PRKD3 CRIM1 SLC8A1 ATL2 CEBPZ BIRC6-AS1 STRN LTBP1 SLC8A1-AS1 CDC42EP3 FEZ2 RNU6-577P	down	*
chr4q27	0.0057837	0.0314769	0.4070179	-0.6125676	-1.752599	12	TRPC3 KIAA1109 TNIP3 ANXA5 EXOSC9 PRDM5 NDNF	down	*
chr1q32	0.0000710	0.0011246	0.5384341	0.3966252	1.741815	140	LEMD1 MROH3P MYBPH LAD1 ASCL5 NEK2 PPFIA4 FLVCR1 UBE2T TNNI1 MIR205HG PKP1 PLEKHA6 SNX25P1 KIF14 CR1L KLHDC8A DTL TMEM81 IKBKE TNNT2 HHAT VASH2 SMYD2 RNU6-418P SYT2 LINC00862 IPO9 SLC45A3 LRRN2 SERTAD4 TRAF5 SNRPE IRF6 INTS7 NFASC PCAT6	up	**
chr2p16	0.0018191	0.0129178	0.4550599	-0.4468134	-1.731367	36	LHCGR CCDC88A RNU4-49P SPTBN1 VRK2 FOXN2 FBXO11 REL PRORSD1P CCDC85A TSPYL6 STON1 ACYP2 RTN4 PSME4 RNU6-433P NONOP2 CHAC2	down	*
chr5q31	0.0000742	0.0011246	0.5384341	0.3889762	1.724410	149	SPATA24 KIF20A PCDHGA10 SPOCK1 NRG2 PCDHGA9 PCDHGA5 PCDHGA7 NPY6R PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 FSTL4 PCDHGA11 PCDHGA8 PCDHGB8P PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 CDC25C NME5 GNPDA1 PROB1 KLHL3 MYOT CXCL14 HARS2 PCDHGA2 RN7SL68P CATSPER3 CDC23 SLC22A5 MTND5P11 SLC4A9 KDM3B ACSL6 SIL1 RAD50 PCDHGB1 BRD8	up	**
chr2q33	0.0009700	0.0080736	0.4772708	-0.3663448	-1.718352	78	BMPR2 SNORD11 HSPE1 BZW1 CLK1 COQ10B PLEKHM3 KLF7 CYP20A1 KLF7-IT1 C2orf69 MOB4 SF3B1 CREB1 TRAK2 SNORD70 AOX1 ORC2 PPIL3 NBEAL1 INO80D METTL21A FAM126B NRP2 HNRNPA1P35 ICOS MIR2355 ANKRD44-IT1 FTCDNL1 CCNYL1 CFLAR KCTD18 ANKRD44 PLCL1 PGAP1 NOP58	down	**
chr7p11	0.0052780	0.0292875	0.4070179	0.6559722	1.718013	12	PSPH CCT6A EGFR-AS1 EGFR ZNF713 SEC61G CHCHD2 LANCL2 SUMF2 PHKG1 VOPP1	up	*
chr14q12	0.0021202	0.0146347	0.4317077	0.4578916	1.704783	51	NOVA1 COCH LTB4R2 NOP9 EMC9 REC8 TGM1 LTB4R PSME2 NFATC4 ARHGAP5-AS1 HECTD1 DHRS1 RNU6-455P RNF31 NEDD8 AKAP6 HEATR5A ARHGAP5 NUBPL GMPR2 TSSK4 DTD2 RIPK3 DCAF11 KHNYN HIGD1AP17 PSME1 CBLN3 TM9SF1	up	*
chr1p33	0.0078300	0.0402888	0.3807304	-0.4607194	-1.704110	29	TAL1 CYP4B1 MKNK1 CYP4Z1 CYP4Z2P CYP4A11 MOB3C EFCAB14 CYP4X1 MKNK1-AS1 CYP4A22 ATPAF1 TEX38	down	*
chr5p12	0.0085255	0.0430841	0.3807304	0.6329091	1.696931	13	PAIP1 NNT-AS1 NNT C5orf34 CCL28 MRPS30 RPL29P12 ANXA2R EEF1A1P19	up	*
chr19p12	0.0034046	0.0203905	0.4317077	0.5345409	1.689125	25	ZNF714 ZNF726 ZNF730 LINC00664 VN1R81P ZNF93 ZNF90 ZNF257 ZNF66 ZNF91 ZNF681 ZNF682 ZNF43 ZNF675 ZNF429	up	*
chr19q13	0.0000000	0.0000018	0.7337620	0.3341296	1.676783	594	RHPN2 CEACAM1 KLC3 FOXA3 CEP89 GRIN2D FBXO27 PDCD2L NPAS1 TMEM86B PTPRH WDR88 GPATCH1 LHB BRSK1 ZNF285 CNTD2 GPI ZNF221 SPINT2 LSR ARHGAP33 ZNF888 PHLDB3 SLC7A9 ZNF283 COX6B2 LIPE-AS1 LILRB4 EPS8L1 SIPA1L3 HAUS5 WDR62 RUVBL2 ZNF607 C19orf48 DYRK1B KCNN4 ZNF850 CBLC LINC00665 PAFAH1B3 MYBPC2 ZNF112 ZNF587B NCCRP1 PSENEN ZNF766 SYNE4 SAE1 IRF3 LIPE PDCD5 CCDC114 ZNF146 ZNF226 ZNF530 CAPN12 LIG1 SARS2 CGB7 FBL CLIP3 XRCC1 PIH1D1 DNAAF3 TIMM50 AKT2 GEMIN7 ZNF507 RNU6-611P PPP5C SYMPK FUT2 CNOT3 ZNF587 ERCC2 HSPBP1 SRRM5 PPP1R37 ZNF229 ISOC2 ZNF480 APLP1 SUPT5H DMKN ZNF45 CCDC61 CEACAM16 SIGLEC12 ZNF260 VN1R1 SPACA4 ZNF541 GIPR SMG9 ZNF419 MAP3K10 KCNJ14 RN7SL789P FAM98C ZNF584 MRPS12 THAP8 ETFB CXCL17 PSMC4 ZNF324B DHX34 ZNF606 CATSPERG C19orf18 GRAMD1A OVOL3 ZNF671 C19orf47 ZNF233 JOSD2 SNRPA LRFN3 ZNF468 ZNF234 ZNF544 ZNF417 KCNC3 CADM4 ZNF761 PINLYP ZNF816 MEGF8 LIN37 BCL2L12 POLD1 FXYD3 ZNF814 PRRG2 ZBTB45 ZNF416 MAMSTR EPN1 FAM71E1 ZNF841 STRN4 CA11 ZNF428 ZNF616 CLASRP ZNF497 PPP6R1 ZNF780B IGFL2 ZNF320 MYPOP ZNF160 ZNF223 CACNG8 ZNF446 CYP2S1 ZNF432 PRMT1 NOSIP TMEM147 KPTN ZNF749 ZNF599 EXOSC5 POLR2I SLC1A5 PRKD2 FFAR2 ZNF765 ZNF780A ZNF274 NTN5 EIF3K U2AF2 NUP62 ZNF580 CEACAM5 ZNF837 AP2S1 TPM3P9 ZNF571-AS1 ZNF224 CYTH2 C19orf33 RBM42 RCN3 ECH1 SNRPD2 BLVRB PAK4 CTU1 ZNF404 CCDC9 PRPF31 HAS1 ZFP14 PPFIA3 MARK4 ZNF71 SAMD4B ZSCAN22 SNRNP70 CHMP2A ZNF573 FAM83E TBCB ZNF610 ETHE1 ALKBH6 CLEC11A ZNF567 PNKP CPT1C EIF5AP3 ZNF793	up	***
chr5q35	0.0005447	0.0051383	0.4772708	0.3962443	1.675168	112	CDHR2 CPLX2 GABRP SUDS3P1 CBY3 FAM153B FAM153A THOC3 ZFP62 SFXN1 STC2 SPDL1 SIMC1 BOD1 MSX2 B4GALT7 MGAT4B ZNF346 TRIM41 SNORA74B TRIM7 GPRIN1 RNF44 ZNF454 ZNF354A TBC1D9B TSPAN17 DBN1 RAB24 CLTB RMND5B HMGB3P22 PHYKPL UIMC1 NSD1 SH3PXD2B SCGB3A1 FBXW11 ERGIC1 GRM6 TMED9 HRH2 MXD3 PRDX2P3 ZNF354B DDX41 ADAMTS2 TRIM52 FAF2 NHP2 NPM1 RUFY1 HNRNPAB	up	**
chr12q13	0.0001409	0.0015945	0.5188481	0.3650213	1.674928	199	KRT5 NXPH4 TROAP GALNT6 TIMELESS DNAJC22 ASIC1 RACGAP1 IGFBP6 NABP2 ESPL1 B4GALNT1 SPATS2 DTX3 PIP4K2C SHMT2 SMUG1 MYL6B DCTN2 SLC4A8 SMAGP METTL7B GPR182 ANKRD52 HOXC6 WNT1 BLOC1S1 LETMD1 CSRNP2 SNORA2A TFCP2 R3HDM2 CNPY2 SLC39A5 MYO1A TMEM106C CBX5 KRT18 KIF5A STAT2 PMEL FAM186A ACVR1B PA2G4 KCNH3 OR10AD1 SCN8A OS9 BCDIN3D-AS1 BAZ2A RDH16 LIMA1 DGKA ORMDL2 ERBB3 AAAS MIR4698 WNT10B KRT8 DDX23 STAC3 CACNB3 NFE2 SUOX SMARCC2 COPZ1 MCRS1 RPS26 PRIM1 STAT6 PFKM IKZF4 DIP2B TARBP2 ADCY6 DNAJC14 OR5BK1P SLC38A4 KRT80 TUBA1C C12orf10 PRKAG1	up	**
chr5p13	0.0044698	0.0256593	0.4070179	0.4328952	1.643294	57	PRLR DROSHA WDR70 GOLPH3 NUP155 C6 SPEF2 AMACR SKP2 AIG1P1 OSMR KRT18P31 RPS4XP6 TTC23L NADK2 FBXO4 SLC1A3 ADAMTS12 RAI14 C5orf22 DNAJC21 C1QTNF3 OXCT1 OFD1P17 RAD1 BRIX1 LMBRD2	up	*
chr3p23	0.0090566	0.0449654	0.3807304	0.8747665	1.639179	4	ZNF587P1 ZNF860 OSBPL10-AS1	up	*
chr7q11	0.0026381	0.0173622	0.4317077	0.4251196	1.623613	62	STAG3L2 ZNF273 ZP3 ZNF138 PMS2P5 SKP1P1 ZNF117 ERV3-1 ZNF107 PMS2P4 LINC00174 DTX2P1 KCTD7 TYW1 SNORA22 FDPSP7 DTX2 UPK3BP1 CCDC146 STAG3L4	up	*
chr17q22	0.0074436	0.0391722	0.4070179	0.4603408	1.620236	40	ANKFN1 COIL MKS1 CUEDC1 COX11 MPO RNF43 AKAP1 TOM1L1 STXBP4 PPM1E GDPD1 DYNLL2 RN7SL449P TRIM37 MSI2 MRPS23 SRSF1 PRR11	up	*
chr3q27	0.0074746	0.0391722	0.4070179	0.4112221	1.560972	60	EPHB3 ECE2 EIF2B5 CLCN2 MAGEF1 TMEM41A RPL4P4 RPL39L IGF2BP2 MAP3K13 ABCC5 YEATS2 EHHADH THPO ALG3 RTP4 YEATS2-AS1 POLR2H VWA5B2 DVL3 MAP6D1 PSMD2 CHRD ABCF3 ABCC5-AS1 BCL6 EIF4G1 MCF2L2 LINC00888 CRYGS PARL	up	*
chr14q11	0.0045334	0.0256593	0.4070179	0.3729181	1.558542	102	ZFHX2 THTPA AP1G2 C14orf93 EIF4EBP1P1 ANG SALL2 BCL2L2-PABPN1 PABPN1 PSMB5 METTL3 ABHD4 TEP1 TRAJ20 DHRS4-AS1 MRPL52 TRAJ17 SUPT16H RPGRIP1 RPPH1 HAUS4 PPP1R3E PRMT5 TMEM253 TRAJ26 TRAJ42 OSGEP TRAJ14 TRAJ28 APEX1 TRAJ11 ACIN1 PARP2 TTC5 TRAJ37 TRAJ12 TRAJ1 TRAJ4 TRAJ18 TRAJ32 CHD8 DHRS4L2 DHRS4 HOMEZ MMP14 TRAJ24 CDH24 TRAJ44 METTL17 DAD1 TRAJ41 TRAJ38 AJUBA TRAJ19 ARHGEF40	up	*
chr6p21	0.0013037	0.0099713	0.4550599	0.3469246	1.553622	159	UNC5CL KCNK5 SPDEF IP6K3 SLC26A8 SAYSD1 XPO5 GUCA1B SRPK1 AARS2 C6orf132 DNPH1 CUL9 CUL7 MDFI BRPF3 PEX6 DNAH8 ARMC12 ADCY10P1 NFYA C6orf223 DDR1 PPIL1 TTBK1 MEA1 ETV7 CMTR1 PACSIN1 POLR1C OARD1 TCTE1 UQCC2 ITPR3 TAPBP YIPF3 MAPK13 TSPO2 ANKRD18EP TJAP1 DLK2 SYNGAP1 ABCC10 KLC4 KLHDC3 MDGA1 HMGA1 ZNF76 RPL7L1 LRRC73 ZBTB9 RRP36 GLO1 MRPL14 APOBEC2 STK38 TRERF1 CCDC167 GTPBP2 UHRF1BP1 TMEM63B SUPT3H ENPP5 LEMD2 SNRPC PPP2R5D	up	**
chr20q11	0.0032458	0.0203905	0.4317077	0.3558298	1.524567	122	DNMT3B TPX2 VSTM2L ARHGAP40 UQCC1 CEP250 KIF3B BPIFB1 RPS3P2 SNHG11 AHCY SNORA71D BPIFB9P TTLL9 E2F1 CPNE1 TTI1 FER1L4 CBFA2T2 EIF6 POFUT1 NFS1 GSS COMMD7 HM13-IT1 PDRG1 TM9SF4 EFCAB8 RPRD1B BCL2L1 BLCAP PIGU ROMO1 SNORA71A MMP24 MYH7B ERGIC3 SPAG4 SNORA60 MANBAL CDK5RAP1 RNU6-759P MAP1LC3A ZNF341 ACTR5 TRPC4AP DSN1 RBL1 ITCH-AS1 SNHG17 ASIP DUSP15 DLGAP4 SNTA1 CDC42P1 NCOA6 GGT7 HM13 SNORA71C SNORA71B FOXS1 SRC RALGAPB MIR4755 PLAGL2	up	*
chr17p13	0.0011348	0.0089206	0.4550599	-0.2669529	-1.430852	197	ZMYND15 CXCL16 ASGR1 SCIMP MIR22HG ARHGEF15 GLTPD2 C17orf107 INPP5K SENP3-EIF4A1 VAMP2 CLEC10A SAMD11P1 SCARF1 TLCD2 ZBTB4 EIF4A1 RILP CHRNE NDEL1 CRK CYB5D2 KIF1C SPNS3 P2RX5-TAX1BP3 MED11 TNFSF12 LINC00324 PER1 PAFAH1B1 PIK3R5 SLC35G6 MYO1C SENP3 SLC16A11 HIC1 ELP5 VMO1 RNASEK BCL6B TNFSF13 ADPRM RN7SL608P TMEM107 TIMM22 PITPNA SLC43A2	down	**

C2 curated genes Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER	0.0000000	0.0000000	1.4099514	0.7005670	3.037726	127	TRIP13 FOXM1 HELLS KIF20A HJURP MCM10 FANCI BUB1B NEK2 CCNB1 CENPF POLQ PBK KIF18B NDC80 BRCA1 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 DNMT3B ASPM STIL PLK1 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 PRC1 CCNF DTL GINS4 ZWINT SPDL1 MELK HMMR KIF23 CEP55 PAQR4 MKI67 KIF15 PAFAH1B3 BUB1 TOP2A AURKA POLA2 KIF2C RRM2 KIF11 CHAF1B LMNB1 CHEK1 MAD2L1 RAD51AP1 NUSAP1 ASF1B CDK1 BIRC5 GMNN E2F1 NCAPG DNA2 FEN1 EZH2 SPAG5 DPP3 DLGAP5 TACC3 MAPK13 TK1 DTYMK ANP32E KIF20B	up	***
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN	0.0000000	0.0000000	1.1421912	-0.6058907	-3.034916	124	PTP4A2 SIK1 THAP2 YPEL5 TMX4 CCNL1 CNST TRA2B SBDS PPP1R15B EIF1 EIF5 MAP3K8 CSGALNACT2 KLF10 FOXP1 KLF6 EIF4E GATA3 RGCC CLK1 PDE4D MCL1 TIPARP CSRNP1 MOAP1 SRSF5 KLF4 ZFAND5 STK17B MGAT4A ID2 PER1 RNF139 CCDC59 IKZF5 CNOT6L RSRC2 BTG1 MYLIP AREG CREM HECA JUN EPC1 PPP1R15A PTGER4 IFRD1 PNPLA8 MPZL3 IDS ZBTB24 REL PELI1 PTP4A1 FOSB ING3 CD6 IRS2 C16orf72 GABARAPL1 TOB1 RGS2 HAUS3 AMD1 JUND IER5 SIK3 MEX3C G3BP2 JMJD1C B3GNT2 ZFAND2A PMAIP1 NR4A2 HIPK1 ZFP36 CD69 TSC22D2 SETD2 NR4A3 ZNF331 DUSP2 FBXO33 SON	down	***
SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP	0.0000000	0.0000000	1.3877461	0.6909568	3.009681	132	TRIP13 FOXM1 KIF20A HJURP CDC45 PARPBP MCM10 TROAP BUB1B NEK2 CCNB1 CENPF TIMELESS POLQ KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 GMPS ASPM STIL PLK1 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 TPX2 CCNB2 MCM4 MCM2 RAD54B CDC25A MYBL2 PRC1 MIS18A SHMT2 XPOT ZWINT NME1 MELK HMMR EXO1 NUDT1 CEP55 MKI67 KIF15 MRPL15 BUB1 TOP2A CCT5 AURKA KIF2C RRM2 KIF11 MCM3 LMNB1 CHEK1 DNAJC9 MAD2L1 DSCC1 PKMYT1 BLM NCAPG2 NUSAP1 CDK1 BIRC5 E2F1 NCAPG FEN1 EZH2 SPAG5 QPRT RNASEH2A DLGAP5 TACC3	up	***
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP	0.0000000	0.0000000	1.6024311	0.6041507	2.876224	288	TRIP13 FOXM1 HELLS KCNK5 CDC45 TICRR MCM10 FANCI C1QTNF6 DEPTOR TROAP BUB1B NUP107 XYLB CCDC34 TIMELESS POLQ UBE2T C21orf58 PBK TTF2 SLC2A1 BRCA1 DEPDC1B CDCA7 TTK GINS1 CDCA2 RACGAP1 IQGAP3 E2F8 GTSE1 SLC27A2 ANLN TRAIP POLE ASPM STIL PLK1 AURKB PTTG1 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 STC2 RBBP8 H19 UHRF1 MCM4 MCM2 RAD54B TYMS MYBL2 CA12 PRC1 XRCC2 DTL GLB1L2 MCM8 MIS18A NCAPD2 ZWINT CDT1 SPDL1 NME1 WDR62 NR2C2AP MELK NOS1AP EXO1 KIF23 CEP55 CHAF1A PAQR4 MKI67 KNTC1 BUB1 FANCA TOP2A CENPL AURKA POLA2 POLD2 KIF2C MCM7 E2F2 CLSPN MPHOSPH9 RRM2 MMS22L CDCA5 WDHD1 RAD54L KIF11 FANCD2 MCM3 CHAF1B LMNB1 LIG1 BRI3BP SLC9A3R1 CHEK1 CENPO SPC24 DSCC1 PKMYT1 BRIP1 RAD18 BLM TST SKP2 INCENP KNSTRN NCAPG2 NUSAP1 CBX5 ASF1B CDK1 POLE2 EXOSC2 CENPJ BIRC5 RAPGEFL1 GMNN E2F1 UNG NCAPG L2HGDH DNA2 FEN1 SPAG5 TMEM120B RECQL4 RNASEH2A SNRNP25 MYO19 DNMT1 FANCG DLGAP5 SLC26A2 TACC3 TK1 CHTF18 ESCO2 SLC22A5 GINS2 MAP6D1 POLD1 NUP85 ATAD5 DHTKD1 CENPM WDR34 MCM6 MCM5 TFAP4 GINS3 LRIG1 EXOSC5 HAUS4 LSM4 CHRNA5 ATAD2 CEP85 SUV39H2 CCNA2 ADCY1 PRIM1 PRR11 SHCBP1 RFC5 RAD51 ZWILCH ARHGAP11A WDR76 CELSR2 SMC2 TONSL	up	***
LEE_EARLY_T_LYMPHOCYTE_UP	0.0000000	0.0000000	1.1601796	0.6932281	2.865219	90	KIF20A MCM10 FANCI BUB1B NEK2 CCNB1 UBE2T PBK KIF18B NDC80 TTK GINS1 CDCA2 E2F8 KIF14 ASPM CEP70 NUF2 CENPA PTTG1 TFDP2 CCNB2 UHRF1 MCM4 MCM2 TYMS CDC25A PRC1 DTL MELK HMMR CEP55 MKI67 KIF15 BUB1 TOP2A AURKA KIF2C E2F2 CENPW RRM2 KIF11 RAD51AP1 DSCC1 TSHR PON1 NUSAP1 CDK1 TNFRSF21 BIRC5 NCAPG NEIL3 DIAPH3 RAPGEF5 DLGAP5	up	***
FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN	0.0000000	0.0000000	1.2627399	0.6236454	2.771044	160	FOXM1 KIF20A HJURP AK4 CDC45 PARPBP FANCI HBA1 TROAP CHEK2 BUB1B HBA2 NEK2 UGT8 CCNB1 CENPF TIMELESS POLQ UBE2T MND1 PBK KIF18B NDC80 DEPDC1 BRCA1 PHGDH DEPDC1B TTK GINS1 CDCA2 RACGAP1 IQGAP3 E2F8 GTSE1 KIF14 ANLN TRAIP ASPM PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 GRIN2A TPX2 CCNB2 MYBL2 PRC1 XRCC2 DTL NCAPD2 ZWINT MELK HMMR EXO1 KIF23 MKI67 KIF15 KNTC1 BUB1 TOP2A CENPL AURKA KIF2C POC1A RRM2 CDCA5 KIF11 FANCD2 LMNB1 SLC35G2 MAD2L1 CKAP2L RAD51AP1 BRIP1 BLM PSRC1 KNSTRN CKS1B NCAPG2 NUSAP1 CDK1 SERTAD4 BIRC5	up	***
KOBAYASHI_EGFR_SIGNALING_24HR_DN	0.0000000	0.0000000	1.3951871	0.5920484	2.754005	231	HMGA2 DKK1 TFPI2 TRIP13 HELLS HJURP CDC45 MCM10 FANCI BUB1B NEK2 CCNB1 TIMELESS PBK KIF18B NDC80 DEPDC1 BRCA1 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 ASPM STIL PLK1 CDCA8 AURKB CENPA ECT2 ESPL1 CDC6 SOX9 TPX2 MCM4 MCM2 RAD54B TYMS CDC25A MYBL2 PRC1 ORC1 CCNF GALNT10 DTL ZWINT CDT1 SPDL1 NME1 RANBP1 MELK HMMR EXO1 KIF23 CEP55 CHAF1A MKI67 DCBLD2 KIF15 BUB1 EEF1E1 TOP2A PUS7 AURKA CARD10 POLA2 KIF2C MCM7 RRM2 KIF11 GPSM2 MCM3 LMNB1 CDC42EP1 DNAJC9 ORC6 MAD2L1 RAD51AP1 DSCC1 PKMYT1 BLM PSRC1 CKLF CKS1B NCAPG2 NUSAP1 ASF1B CDK1 POLE2 UCK2 RFWD3 BIRC5 GMNN POLR3K E2F1 UNG NCAPG STEAP1 GJB3 PSAT1 FEN1 EZH2 SPAG5 PA2G4 RNASEH2A RANGAP1 FAM86C1 TUBG1 DLGAP5 LMNB2 TUBB2A TK1 GINS2	up	***
WHITEFORD_PEDIATRIC_CANCER_MARKERS	0.0000000	0.0000000	1.0959293	0.6483061	2.753070	106	CDC45 NEK2 CCNB1 CCDC34 CENPF POLQ UBE2T MND1 PBK CDCA7 TTK CDCA2 CDK4 KIF14 NUF2 CDCA8 CENPA PTTG1 ESPL1 TPX2 GAPDH CCNB2 UHRF1 MCM4 TYMS CDC25A MYBL2 PRC1 ZWINT NME1 MELK NUDT1 PON3 MKI67 PAFAH1B3 BUB1 TOP2A AURKA MCM7 RRM2 CDCA5 KIF11 SOX4 MAD2L1 CKS1B NUSAP1 ASF1B GABRB2 CDK1 POLE2 BIRC5 E2F1 PSAT1 RECQL4 RNASEH2A DNMT1 ILF2 DLGAP5 LMNB2 TK1 DTYMK GINS2 ZNF300	up	***
ZHAN_MULTIPLE_MYELOMA_PR_UP	0.0000000	0.0000000	0.9325952	0.7738207	2.699421	38	TRIP13 FOXM1 MCM10 FANCI BUB1B NEK2 CCNB1 CCDC34 UBE2T DEPDC1B TTK RACGAP1 E2F8 KIF14 ASPM NUF2 TPX2 CCNB2 TYMS PRC1 TOP2A CENPL AURKA RRM2 SPC24 DSCC1 NUSAP1 CDK1 BIRC5 EZH2 DLGAP5	up	***
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR	0.0000000	0.0000000	1.0672100	0.6276297	2.686752	112	TRIP13 KIF20A PARPBP NUP107 NEK2 CCNB1 CENPF TIMELESS UBE2T DEPDC1 TTK RACGAP1 E2F8 ANLN ASPM NUF2 CDCA8 CENPA PTTG1 CCNB2 RBBP8 UHRF1 MCM2 MYBL2 PRC1 MCM8 RANBP1 MELK HMMR EXO1 KIF23 CEP55 KNTC1 BUB1 TOP2A ODF2 MCM7 POC1A RAD54L KIF11 MCM3 LMNB1 TOPBP1 DNAJC9 MAD2L1 DCTPP1 KNSTRN NUSAP1 CDK1 BIRC5 E2F1 NEIL3 EZH2 SPAG5 FGFR1OP DLGAP5 KIF22 DTYMK POLD1 MAGOHB CENPK CDC20 PLEK2 CKAP2 TDP1 GINS3	up	***
PHONG_TNF_TARGETS_UP	0.0000000	0.0000000	0.8140358	-0.6203061	-2.685396	60	CXCL3 EREG BMP2 EGR2 CD44 IER2 CCNL1 KLF10 KLF6 PTX3 BTG3 MCL1 BIRC2 ADAMTS9 CXCL2 ATF3 DUSP1 INHBA BTG1 IL6 JUN JUNB DUSP8 CD83 REL TNFRSF10B FOS DUSP5 ETS2 CCL20 GEM ICAM1 IER5 CEBPD EPHA2 NFKBIA LDLR CSF2 EGR1 FJX1 ZFP36	down	***
KONG_E2F3_TARGETS	0.0000000	0.0000000	1.0175448	0.6571261	2.684969	85	KIF20A HJURP BUB1B CCNB1 CENPF UBE2T PBK DEPDC1 BRCA1 RACGAP1 IQGAP3 PLK1 NUF2 CDC6 TPX2 E2F3 FIGNL1 RBBP8 TYMS PRC1 CCNF NCAPD2 SPDL1 MELK HMMR MKI67 BUB1 TOP2A AURKA KIF2C CDCA5 RAD54L KIF11 MCM3 CHAF1B LMNB1 RAD51AP1 SKP2 INCENP NCAPG2 NUSAP1 ASF1B CENPH NCAPG DNA2 FEN1 EZH2 CCNE1 DLGAP5 TACC3 TK1 CENPQ CDC7 CENPK CDC20 RPRD1B CCNA2 PRIM1 SHCBP1 RAD51 F13A1 SMC2 UBE2C FBXO45 GP1BA	up	***
KANG_DOXORUBICIN_RESISTANCE_UP	0.0000000	0.0000000	0.9545416	0.7294233	2.674583	50	FOXM1 HJURP FANCI BUB1B POLQ PBK GINS1 ASPM PLK1 CDCA8 CENPA CDC6 TPX2 MCM4 TYMS PRC1 ZWINT HMMR MKI67 BUB1 TOP2A AURKA POLA2 RRM2 LMNB1 MAD2L1 RAD51AP1 DSCC1 NCAPG2 NUSAP1 ASF1B CDK1 BIRC5 NCAPG TK1 DTYMK CDC20 CENPM	up	***
BOQUEST_STEM_CELL_DN	0.0000000	0.0000000	1.1330899	-0.4955162	-2.671048	198	SEMA6A RAMP3 SWAP70 TEK PECAM1 ENDOU RASIP1 HHEX GATA2 TIE1 PTPRE THBD PTPRB CDH5 ENG KL ARHGEF15 EMCN LMO2 SOX17 CCRL2 GFOD1 KANK3 S1PR1 STX11 NEDD9 GIMAP6 EOGT SCARF1 PDE2A ERG KIAA0355 MMRN2 SH2B3 ZNF385D PTPRM MCTP1 HBEGF RAPGEF4 NLK ABCG1 PCDH12 RNASE1 ADRB2 IL18R1 LHX6 CD93 SRGN MYCT1 FLI1 FABP5 TBC1D9 CLEC1A TSPAN12 ADAMTS9 SOCS2 CLDN5 MYRIP SSH1 LAPTM5 DOCK9 SELP JAM2 ARAP3 HLA-DQA1 ANXA3 VWF CLIC5 RPS6KA2 FAM107A FLT1 AREG CREM BCAR3 SEC14L1 CAPN11 CARD8 RCAN1 PODXL ENPP4 GMFG	down	***
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP	0.0000000	0.0000000	1.1330899	0.5911954	2.622070	157	TRIP13 FOXM1 HELLS KIF20A HJURP FANCI BUB1B NEK2 TRNP1 CCNB1 CENPF IGF2BP3 FLVCR1 PBK KIF18B TTF2 NDC80 DEPDC1 DEPDC1B CDCA7 TTK RACGAP1 E2F8 KIF14 ANLN ASPM NUF2 AURKB PTTG1 ECT2 CDC6 SOX9 TPX2 CCNB2 H19 MCM2 PRC1 DTL PDE9A ZWINT KIF23 CEP55 MKI67 WASF1 PAFAH1B3 TOP2A AURKA KIF2C CDCA5 PKM FHOD3 KIF11 LMNB1 SOX4 SALL2 CD24 ORC6 MAD2L1 CKAP2L RAD51AP1 BACE2 DSCC1 DDR1 TMED3 NUSAP1 CDK1 TNFRSF21 BIRC5 FEN1 EZH2 TMEM51 CCNE1 DLGAP5 MAPK13 SALL4 PAPLN DBN1 GALNT7 MARCKSL1 CDC7 ETV4 CENPK SASS6 CDC20 ASRGL1 SLC1A5 MARCKS NT5DC2 CKAP4 CCNA2 PRR11 SHCBP1 HK2	up	***
CUI_TCF21_TARGETS_2_DN	0.0000000	0.0000000	1.7268308	-0.4255715	-2.619451	742	SEMA3G EPAS1 CXCL3 PRX ARHGAP31 LPIN2 COL25A1 SLC12A6 TEK PDLIM2 EDNRB FGD5 USP12 SECISBP2L CD55 HHEX SOWAHC TBX3 CPEB2 FABP4 MNDA DPYSL2 GIMAP8 RAPGEF2 CYP4B1 ST6GALNAC3 BTNL9 LIPA LRRFIP1 THBD PTPRB CDH5 ARHGEF15 FYN EMCN LMO2 TMOD3 SOX17 CCRL2 ST3GAL6 KANK3 LDB2 MYADM HEATR5B CITED2 THAP2 CALCRL QKI EML1 YPEL5 C8orf58 ARL8B FBXO3 TGFBR3 NEDD9 GIMAP6 SLCO2A1 CBL TGFBR2 FAM49A ABCB1 TEX2 ZEB2 DNAJB14 PDE2A GINM1 TXNIP ERG ARHGAP29 ZBTB4 CD36 ANXA1 UBR3 KIAA0355 WWC2 MMRN2 SH2B3 SEMA3B SLC36A4 TACC1 HECW2 RAPGEF4 LIFR LATS2 RAP1A CHMP1B TMEM204 CLEC14A SERINC1 CYYR1 RANBP9 NLK SPIRE1 CSGALNACT2 HIPK3 PCDH12 CAV2 HLX PAG1 ZBTB8A DACH1 SLAIN2 GATA3 SIRPA CRK ANKRD29 PPP1R13B ZFYVE16 SRGN ITSN2 SOX7 MCL1 MYCT1 FOXC2 TIPARP ATP10A FLI1 PTPN12 AGO4 AMOTL1 ARRB1 SYNPO MTMR6 DUSP3 TLE4 EXOC3L2 AHNAK CCDC82 SORBS1 PTPRO CLEC1A DENND6A NOSTRIN PPM1K LIMS1 TCP11L2 TSPAN12 DAAM2 RNFT1 KLF4 NES FAM76A COQ10B ROCK1 THBS1 TMED5 TPP1 GRK5 MYO1B NPR3 FAM49B TMBIM1 C1QTNF7 PER2 RBMS1 PTPRC VIM CTBS TADA2B ARHGEF26 HOPX CYP20A1 JAM2 TLR4 SHE ILDR2 VAMP5 CALM2 DEGS1 CRIM1 BACE1 AKIRIN1 IKZF5 LMBRD1 TANC1 HSDL2 LIN54 SACM1L NRROS CLIC5 USP25 ARHGAP17 TMEM9B KANK1 MYO1C FMNL2 FRY FLT1 ELF1 VPS37A NSMAF SGK1 CTSS EBAG9 SNAP23 MAGI2 CABLES1 TMTC1 LRCH1 RASSF10 SH3BP5 CPEB4 ETS1 MSRB3 HSPA1B FOXN2 APBB2 JAK1 TBC1D12 AK1 RCAN1 PTGER4 FERMT2 ENPP4 IFRD1 TTC14 ACKR3 MBNL2 FRYL IDS FAM43A MALT1 SERPINB6 HOMER1 TRAK2 PREX2 RALB SNRK CELF2 AGFG1 GPRIN3 CTTNBP2 CALM1 HIVEP2 ICAM2 RIN2 ZNF175 ING3 MME GIMAP1 SPOP EMC7 CHPT1 STXBP3 STRN DCAF5 ITGA9 MTMR2 CBFA2T3 GALC MAP3K2 PCDH17 PLSCR4 TOB1 NBEAL1 MACF1 RGS2 PGGT1B SERINC3 PDE4B INO80D GEM ARAP2 TNFAIP8 SCN7A EPN2 IQSEC1 CDC42EP3 ACAP2 CXCR4 CDKN1C HSP90AA1 TTLL7 TDRP TBC1D1 POLR2M CREBBP ULK2 PARVA MBD5 VSIG10 LYSMD3 NFKBIA GLRX2 RAPGEF3 ABI3 TIMP3 B3GNT2 MTUS1 LYST FAM126B PRKG1 MMD KIF1B TMCC3 RORA FAM13C DOCK4 GIMAP4 EHD4 PURB RNF13 EHD3	down	***
NAGASHIMA_EGF_SIGNALING_UP	0.0000000	0.0000001	0.7881868	-0.6266112	-2.618840	52	SOWAHC MIR22HG SIK1 FOSL1 NEDD9 TRIB1 IER2 HBEGF KLF10 KLF6 NR4A1 MCL1 TIPARP ID3 ATF3 ARC DUSP1 HES1 MAFF AREG RYBP JUN JUNB FOS FOSB DUSP5 PLEKHO2 ETS2 GEM EPHA2 EDN1 EGR1 NR4A2 ZFP36 DNAJB1 BCL10 NR4A3 KBTBD2 DUSP2	down	***
CROONQUIST_IL6_DEPRIVATION_DN	0.0000000	0.0000000	0.9325952	0.6299623	2.589713	88	TRIP13 FOXM1 CDC45 FANCI BUB1B CCNB1 BRCA1 GINS1 KIF14 TRAIP GMPS SPP1 STIL PLK1 AURKB CENPA PTTG1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS CDC25A MYBL2 CCNF ZWINT HMMR CHAF1A MKI67 KNTC1 BUB1 TOP2A AURKA KIF2C MCM7 RRM2 KIF11 MCM3 LIG1 CHEK1 MAD2L1 SKP2 CKS1B CDK1 POLE2 SPAG5 KIF22 TK1 DTYMK ANP32E POLD1 CDC20 HMGA1	up	***
NAGASHIMA_NRG1_SIGNALING_UP	0.0000000	0.0000000	0.9759947	-0.4924633	-2.585376	160	WEE1 SOWAHC GATA2 MIR22HG SIK1 FOSL1 NEDD9 TRIB1 CASP9 IER2 CCNL1 AVPI1 CLCF1 TRA2B SEMA3B HBEGF EIF5 MAP3K8 KLF10 KLF6 NR4A1 NDEL1 MCL1 ZNF365 TUBB6 TIPARP MAP2K3 PLAUR ID3 ZFAND5 PER2 ATF3 ARC PER1 DUSP1 HES1 MAFF AKIRIN1 TGFB2 STK24 SRF AREG SGK1 AQP3 SERPINB8 JUN JUNB DUSP8 PPP1R15A FERMT2 IFRD1 SPATA2L REL HOMER1 TNFRSF10B FOS KLF2 EPPK1 FOSB JMJD6 DUSP5 IRS2 GATA6 RGS2 PLEKHO2 ETS2 GEM PDLIM5 IER5 CDC42EP3 CXCR4 TOB2 PSME4 EPHA2 EDN1 LDLR PMAIP1 SPHK1 EGR1 NR4A2 ZYX ZFP36 YRDC DNAJB1 BCL10 TES NFIL3 NR4A3 ZNF331 KBTBD2 DUSP2	down	***
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP	0.0000000	0.0000000	0.9101197	0.6506098	2.572676	71	HMGA2 KIF20A HJURP NEK2 CCNB1 CENPF PBK EFNA3 GTSE1 ASPM CDCA8 CENPA ESPL1 TPX2 CCNB2 MCM4 TNC SCG5 MELK HMMR CEP55 MKI67 BUB1 TPBG MSX2 TOP2A KIF2C RRM2 KIF11 GPSM2 NUSAP1 APLP1 CDK1 BIRC5 CDH3 CRLF1 DLGAP5 AHNAK2 COL11A1 CDC20 CDH11 CCNA2 FBN2 CENPE UBE2C NPTX2 NCAPH ROR2 MLLT11	up	***
VECCHI_GASTRIC_CANCER_EARLY_UP	0.0000000	0.0000000	1.4245627	0.5223844	2.550336	379	ATP10B TRIP13 MUC13 MYEOV FOXM1 CEP72 KIF20A CDH17 PARPBP MCM10 FANCI TFAP2A PDCD6 BUB1B NEK2 CCNB1 CENPF UBE2T SEMA4B PBK KIF18B THOC3 NDC80 GUCY2C DEPDC1 BRCA1 DEPDC1B CDCA7 C12orf66 LCN2 TTK GINS1 CDCA2 RACGAP1 E2F8 GTSE1 KIF14 ANLN STK31 ILDR1 PMS2P5 SPP1 ASPM COL7A1 NUF2 EFNA4 CENPA PTTG1 ECT2 CDC6 TPX2 CCNB2 FIGNL1 H19 UHRF1 MCM4 STRIP2 MCM2 RAD54B ZNF117 MYBL2 FERMT1 PRC1 EIF3B DTL MARVELD3 XPO5 GINS4 ZWINT SPDL1 WDR90 NME1 RANBP1 RUVBL2 ITGA2 CLDN1 MELK HMMR CEP55 KCNN4 LAMC2 MKI67 KIF15 BUB1 MSX2 TOP2A PUS7 AURKA NUP155 MCM7 CENPW RRM2 CDCA5 HOXC6 SLC4A11 FANCD2 GPSM2 WDR72 CHEK1 PDZK1IP1 ASS1 MAD2L1 PFKP RAD51AP1 DSCC1 BRIP1 RAD18 SKP2 CKS1B NCAPG2 NUSAP1 KRT18 CDK1 CDK12 KCNE3 CENPH BIRC5 CCT3 NCAPG FEN1 CDH3 EZH2 TNRC18 LAPTM4B EFTUD2 RP9 CCNE1 PABPC1L DPP3 DLGAP5 CTSV GSS EPHB2 TK1 ESCO2 IL15RA GINS2 ANP32E MMP7 CENPK PROX1 TIMM13 CDC20 CENPM HMGA1 POP7 CXCL1 WRNIP1 PRMT1 CKAP2 DHX8 XRCC4 MCM5 SNRPD1 AATF ZDHHC11 GAD1 TMEM45B ATAD2 CCNA2 SMARCA4 RBM42 PRR11 TMC5 ABHD10 WDR77 BMS1 RNF123 RARRES1 AIFM2 TMED9 TBCB RBM19 LIF RPN1 PFDN4 PCBD1 CDC25B UBE2C PDP1 SFXN4 MSRB1 ENO1 RASGEF1A E2F7 RRS1 ZNF367 NUP93 TRUB2 ASCL2 C12orf10 ARHGAP8 PMEPA1 CAMK2N1 KLK10 ZNF511 MRTO4 SPIDR MRPS16 NSUN5 SHQ1	up	***
GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN	0.0000000	0.0000000	0.9101197	0.6262947	2.546681	81	TRIP13 CDC45 MCM10 BUB1B KIF18B NDC80 GINS1 RACGAP1 CDC6 CCNB2 MCM4 MCM2 TYMS CDC25A PRC1 HBB DTL ZWINT MELK CEP55 KIF15 BUB1 TOP2A KIF2C RRM2 KIF11 CHEK1 MAD2L1 RAD51AP1 DSCC1 CKS1B NUSAP1 CDK1 POLE2 BIRC5 GMNN NPM3 NCAPG FEN1 RNASEH2A SNRNP25 CCNE1 DLGAP5 TK1 GINS2 NUP85 CDC20 CENPM MCM6 MCM5	up	***
FARMER_BREAST_CANCER_CLUSTER_2	0.0000000	0.0000000	0.8266573	0.7623394	2.542845	31	KIF20A BUB1B NEK2 NDC80 ASPM CENPA PTTG1 TPX2 CCNB2 MCM4 RAD54B PRC1 MELK CEP55 KIF15 MRPL15 BUB1 PRKDC KIF11 MAD2L1 NUSAP1 ESRP1 NCAPG	up	***
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	0.0000000	0.0000000	1.5498781	0.5121418	2.542013	491	TRIP13 DDX11 FOXM1 HELLS KIF20A HJURP AK4 CEP89 CDC45 TICRR PARPBP MCM10 FANCI TROAP CHEK2 BUB1B NUP107 SLFN13 NEK2 CCNB1 CCDC34 CENPF TIMELESS UBE2T PBK KIF18B TTF2 NDC80 PRIM2 DEPDC1 PIF1 DEPDC1B CDCA7 TTK GINS1 CDCA2 RACGAP1 IQGAP3 GTSE1 TRAIP POLE ASPM STIL ANKRD24 CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 MCM2 TYMS UMPS MYBL2 PMS2 PRC1 XRCC2 ORC1 CCNF DLGAP1 DTL MCM8 MIS18A NCAPD2 CDT1 SPDL1 LSM5 TAMM41 LDHB HAUS5 WDR62 TTLL4 MELK HMMR EXO1 NLE1 KIF23 CEP55 MKI67 KNTC1 PAFAH1B3 BUB1 FANCA CCDC77 AUNIP TOP2A CENPL AURKA EME1 POLA2 SLC29A2 POLD2 KIF2C MCM7 MAD1L1 E2F2 CENPW CLSPN RRM2 MMS22L CDCA5 WDHD1 RAD54L ERAL1 KIF11 PASK FANCD2 MCM3 CHAF1B LMNB1 CDC25C LIG1 CHEK1 C7orf50 DNAJC9 THYN1 MAD2L1 CKAP2L RAD51AP1 DCTPP1 XRCC1 SPC24 DSCC1 PKMYT1 RAD18 BLM SLC25A10 SKP2 PSRC1 INCENP KNSTRN CKS1B NCAPG2 CDKN2C NUSAP1 ASF1B CDK1 POLE2 CCDC61 SERTAD4 CENPH BIRC5 C1orf112 TESC GMNN E2F1 UNG NCAPG DNA2 FEN1 EZH2 SPAG5 POC1B SMO RECQL4 CENPP PA2G4 RANGAP1 NET1 DNMT1 LGR5 CCNE1 CEP192 AKR1E2 DLGAP5 NPTXR NMRAL1 TACC3 LMNB2 MNS1 OSBPL3 PTGES2 KIF22 HIRA DUSP12 TK1 CHTF18 CASP7 CENPQ ESCO2 MLEC GINS2 GEMIN5 ANP32E KIF20B NOC2L POLD1 NUP85 SLC1A3 ATAD5 CDC7 RAD50 CENPK SASS6 GEMIN6 PTN CKAP5 L3MBTL2 CDC20 PALB2 CENPM ANKRD6 ERBB3 AAAS GPATCH4 RPA1 MCM6 LPCAT4 CENPT CKAP2 MCM5 ZRANB3 HAUS6 LANCL2 RCC1 HAUS4 LSM4 NT5DC2 ATAD2 CEP152 DDAH1 SUV39H2 CCNA2 PRIM1 PRR11 SHCBP1 RFC5 BLVRB RAD51 SNX7 ZWILCH FBN2 ARHGAP11A RHOT2 WDR76 MXD3 ARHGEF39 SMC2 TONSL CENPE C1orf159 SEPHS1 CDC25B UBE2C TAF4 PTOV1 NUP210 E2F7 ZNF367 C4orf46 SART3 C12orf10 FBXL18 NCAPH GEMIN2 CD38 KIAA0586 TPM1	up	***
REICHERT_MITOSIS_LIN9_TARGETS	0.0000000	0.0000001	0.7749390	0.7788433	2.528936	26	KIF20A CCNB1 CENPF CDCA2 ASPM PLK1 CENPA CCNF NCAPD2 LMLN HMMR KIF23 CEP55 MKI67 TOP2A AURKA KIF2C NUSAP1	up	***
BURTON_ADIPOGENESIS_3	0.0000000	0.0000000	0.8986712	0.6140338	2.506627	84	HELLS KIF20A CDC45 MCM10 CCNB1 BRCA1 CDCA7 TTK RACGAP1 E2F8 PLK1 CDCA8 CDC6 CCNB2 FIGNL1 MCM4 MCM2 TYMS PRC1 CCNF DTL MKI67 BUB1 TOP2A AURKA KIF2C RRM2 KIF11 MCM3 TOPBP1 RAD51AP1 INCENP NUSAP1 ASF1B OSMR CDK1 BIRC5 FEN1 EZH2 DNMT1 ILF2 DLGAP5 TACC3 KIF22 TK1 DTYMK NUP85 CDC7 CENPK CDC20	up	***
HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP	0.0000000	0.0000004	0.7477397	-0.5942012	-2.500221	53	CXCL3 EREG ABHD5 IL1B PRKAR1A MANBA FUCA1 FAM49A TRIB1 MCTP1 HBEGF GM2A BTG2 KLF6 RHOB KLF4 PLAUR CCL3 CDKN1A CXCL2 ATF3 CCL4 ACTR2 PPP1R15A GLIPR1 CHPT1 SOD2 KYNU ETS2 MS4A4A RIPK2 NLRP3 GLUL EMC3 EGR1	down	***
AMIT_EGF_RESPONSE_40_HELA	0.0000001	0.0000025	0.7049757	-0.6299658	-2.498732	39	IER2 CCNL1 BTG2 KLF6 NR4A1 ATF3 DUSP1 HES1 CDKN2AIP PIAS1 IL6 SGK1 RNF141 JUN JUNB PPP1R15A MBNL2 ATL2 PALMD KLF2 DUSP5 MBNL1 LDLR EGR1 ZFP36 PTGS2 DUSP2 CBX4 ID1	down	***
GREENBAUM_E2A_TARGETS_UP	0.0000000	0.0000002	0.7749390	0.7743210	2.481714	25	SCIN HS3ST1 CCNB1 TTK RACGAP1 ANLN ECT2 CCNB2 MKI67 BUB1 TOP2A AURKA KIF2C KIF11 PFKP CDKN2C NUSAP1	up	***
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR	0.0000000	0.0000000	0.8513391	0.6161347	2.479296	78	TRIP13 KIF20A PARPBP NEK2 TIMELESS UBE2T BRCA1 TTK RACGAP1 E2F8 CDCA8 CENPA UHRF1 MCM2 MYBL2 DTL CDT1 RANBP1 EXO1 CEP55 KNTC1 MCM7 POC1A CDCA5 WDHD1 RAD54L KIF11 MCM3 CHAF1B LMNB1 TOPBP1 DNAJC9 MAD2L1 DCTPP1 NUSAP1 GMNN E2F1 EZH2 DLGAP5 KIF22 DTYMK GINS2 SAP30 MAGOHB CENPK MCM6 MCM5 GINS3 CCNA2 RFC5 RAD51	up	***
NIKOLSKY_BREAST_CANCER_12Q13_Q21_AMPLICON	0.0000000	0.0000001	0.7749390	0.7099040	2.476452	38	TSPAN8 MDM1 NUP107 CPSF6 AVIL RAB3IP TSFM PTPRR C12orf66 METTL1 CDK4 YEATS4 CYP27B1 SLC35E3 KCNMB4 CAND1 XPOT CCT2 FRS2 MDM2 DYRK2 CTDSP2 TSPAN31 LGR5 CNOT2 OS9	up	***
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6	0.0000000	0.0000000	1.3651796	0.5034047	2.474713	408	TRIP13 FOXM1 HELLS KIF20A EGLN3 HJURP PKP2 AK4 CDC45 PARPBP MCM10 FANCI ELOVL6 TROAP BUB1B NEK2 UGT8 CCNB1 CENPF SLC9A2 IGF2BP3 PBK KIF18B TTF2 SLC2A1 MUC16 NDC80 PRIM2 DEPDC1 TBRG4 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 ASPM NABP2 YEATS4 CDCA8 AURKB CENPA PTTG1 CDC6 SFXN1 TPX2 GAPDH CCNB2 STC2 MCM4 TYMS XPNPEP1 CDC25A MYBL2 PRC1 ORC1 DTL GINS4 NCAPD2 ZWINT CDT1 KAZALD1 NME1 LDHB WDR62 RUVBL2 MELK HMMR EXO1 GPR37 KIF23 CEP55 MKI67 KIF15 KNTC1 WASF1 BUB1 FANCA TOP2A CCT5 AURKA VANGL1 YKT6 SNCG KIF2C MPHOSPH9 RRM2 PRKDC WDHD1 RAD54L PKM KIF11 GPSM2 LMNB1 CDC25C PFN2 YEATS2 CHEK1 DNAJC9 MAD2L1 PFKP RAD51AP1 BRIP1 CAD SLC25A10 PSRC1 THOP1 NCAPG2 CDKN2C CMAS NUSAP1 PLOD2 CBX5 CDK1 POLE2 EXOSC2 BIRC5 NCAPG DNA2 KIF2A PSAT1 NEIL3 SSX2IP EZH2 SPAG5 ARTN SEMA3A PRKAA2 RECQL4 DENND1A FGFR1OP SRD5A1 PA2G4 CCNE1 TUBG1 DLGAP5 MRGBP UBAC1 PSMA5 TRMU CTSV GSS TACC3 TK1 DTYMK CENPQ POMT2 GINS2 AGPAT5 STEAP1B SAP30 TWF1 MAGOHB CDC7 STRN4 CDC20 CENPM HMGA1 UBE2V2 MCM6 ZNF248 PRMT1 CKAP2 MCM5 GINS3 LSM4 CHRNA5 WDYHV1 ATAD2 TSR1 NUP62 AP2S1 AGMAT CCNA2 ADM PRIM1 SHCBP1 ELOVL4 HK2 TUBA4B SNX7 CARHSP1 ZWILCH	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP	0.0000000	0.0000000	0.8634154	-0.4909785	-2.468707	127	CXCL3 SOWAHC ZC3H12C MIR22HG BACH1 FOSL1 UBE2FP1 TRIB1 CNST HBEGF EIF5 SPIRE1 ZBTB21 PPP3CC PLAUR PXDC1 MAP1LC3B MAFG ATF3 ZBTB43 BRF2 INHBA RYBP VPS37A CREM CPEB4 HSPA1B DNAJA1 RCAN1 IFRD1 PNPLA8 KBTBD8 ZNRF3 RNF24 SLC3A2 CHORDC1 SAV1 AKIRIN2 JMJD6 SMCR8 C16orf72 GNA13 N4BP2L2 JUND SERTAD1 TMEM217 CREBBP OSER1 MAFK DNAJB9 TNFSF9 KIF1B SAMSN1 RORA ZFAND2A PMAIP1 HERPUD1 SLC19A2 YRDC DNAJB1 NFIL3 HSPB8 SRXN1 CASP3 EMP1 PNP CBLL1	down	***
WHITFIELD_CELL_CYCLE_LITERATURE	0.0000000	0.0000000	0.8140358	0.6890060	2.468252	44	KIF20A CDC45 BUB1B CCNB1 CENPF BRCA1 RACGAP1 PLK1 CENPA CDC6 CCNB2 MCM2 TYMS CDC25A CCNF BUB1 TOP2A AURKA RRM2 CDC25C CDKN2C CDK1 BIRC5 E2F1 CCNE1 CDC20 MCM6 MSH2 CCNA2	up	***
WINNEPENNINCKX_MELANOMA_METASTASIS_UP	0.0000000	0.0000000	0.9759947	0.5597129	2.466057	147	CDC45 PARPBP NEK2 CCNB1 CENPF TIMELESS UBE2T KIF18B NDC80 PHF14 PRIM2 RACGAP1 ANLN GMPS ASPM NUF2 CDCA8 CENPA PTTG1 ECT2 CDC6 CCNB2 UHRF1 MCM4 TYMS PRC1 ZWINT NME1 RANBP1 MELK EXO1 CEP55 DCBLD2 KNTC1 BUB1 TOP2A CCT5 AURKA KIF2C RSRC1 RRM2 CDCA5 RAD54L KIF11 KDELR2 CHEK1 DSCC1 ZNF587 KNSTRN CKS1B NCAPG2 PLOD2 CDK1 BIRC5 EEPD1 GMNN NCAPG NEIL3 SPAG5 UBFD1 DLGAP5 TK1 DTYMK GINS2 RBM33 CCT7 GEMIN6	up	***
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP	0.0000000	0.0000000	1.0175448	0.5560925	2.465977	158	TRIP13 KIF20A CDC45 MCM10 FANCI ELOVL6 BUB1B NEK2 CCNB1 DNAJC12 CENPF PBK KIF18B NDC80 SORD BRCA1 TTK GINS1 RACGAP1 E2F8 ASPM AURKB CENPA ECT2 ESPL1 CDC6 SFXN1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 HBB SHMT2 ZWINT LSM5 RANBP1 MELK HMMR NUDT1 CEP55 KIF15 BUB1 TOP2A AURKA KIF2C MPO RRM2 TFR2 KIF11 CHEK1 MAD2L1 RAD51AP1 DSCC1 TST IDH2 CKS1B NUSAP1 CDK1 POLE2 BIRC5 GMNN NPM3 NCAPG SLC25A13 FEN1 EZH2 SPAG5 ITGA2B RNASEH2A SNRNP25 CCNE1 DLGAP5 TK1 GINS2 NUP85 CDC7 CDC20 CENPM LRRC59	up	***
LINDGREN_BLADDER_CANCER_CLUSTER_2B	0.0000000	0.0000000	1.1866510	-0.4315208	-2.464117	334	RAMP3 CD52 IL1A FOXF1 SOX18 PECAM1 HHEX GLIPR2 LRRC8C DPYSL2 THBD LINC00472 FYN STXBP6 SAMHD1 GFOD1 CAV1 MYADM RTN3 FLVCR2 CLEC10A PRKAR1A BCL2A1 IER2 SEMA6D STARD4 SH2B3 DNAJC3 TACC1 LATS2 ENTPD1 CSRP1 IFI30 PARVG ANPEP LCP1 STOM NR4A1 JAM3 SIRPA TNS1 CRTAM SRGN EPB41L2 SLC7A2 EVI2B CYBRD1 SYNPO DAAM2 KLF4 AOC3 PLAUR NES DAB2 ZFAND5 ADAMTS9 SOCS2 GRK5 CLIC4 LAPTM5 COTL1 SELL CD302 LBH ALOX5AP EVI2A ACTG2 IL7R AFF1 CNRIP1 EMP3 PHTF2 SOCS3 LAMB2 TMTC1 JUN MT1L RAC2 PODXL GLIPR1 MALT1 YWHAZ LGALS2 RALB CST7 CELF2 MCAM PELI1 LMCD1 CALM1 RUNX3 PPTC7 TIMP2 TCF4 DUSP5 RELL1 COL15A1 MFNG RGS2 NRN1 ABI3BP BMP2K GEM ICAM1 MOB3B ARPC2 CDC42EP3 MS4A4A CXCR4 DHRS12 ALDH2 TRAF1 OSER1 NFKBIA ADORA2A KLRK1 B3GNT2 DNAJB9 SAMSN1 NRP2 MT2A IL16 DNAJB5 LYZ SLFN11 EGR1 CFL2 DKK3 HMGCS1 PRKCH ITGAL EBF1 MT1E GNG11 HLA-DRB1 AKAP12 TES SLC43A3 NFIL3 PDPN EDIL3 IL32 MAPK7 ARHGAP30 NFKBIZ EBI3 MYO1F MYO5A MT1X MYL9 ADAM19 MYLK GSN SON FERMT3 SPAG7 C3AR1 ANXA6 KLRG1 SERPING1 IL10RA EFEMP1 MT1G	down	***
ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF	0.0000000	0.0000000	0.9969862	-0.4533804	-2.457145	206	WEE1 IL1A OLR1 DLC1 KLF13 CD55 SOWAHC ZC3H12C CPEB2 IL1B RAPGEF2 CLDND1 SIK1 OTUD1 MYADM GPCPD1 STX11 IL1RN TRIB1 CASP9 CCNL1 NCEH1 B3GNT5 HBEGF SGMS2 LATS2 CHMP1B MTF1 MAP3K8 NR4A1 TFRC MCL1 TIPARP CSRNP1 RN7SL368P RN7SL600P ITPRIP ZSWIM6 KLF4 PLAUR TJP1 ADAMTS9 DENND3 PER2 NFKB1 RBMS1 CXCL2 ATF3 PER1 DUSP1 SMAD7 HES1 MAFF AFF1 MMP19 SERTAD2 IL6 SOCS3 ARL5B ETS1 HRH1 JUNB RCAN1 PPP1R15A FERMT2 MBNL2 SNRK FOS PELI1 PTP4A1 HIVEP2 MBP PPTC7 FOSB TGIF1 MIR23A DUSP5 NAB1 ATXN1 TOB1 GATA6 RIMKLB RGS2 ETS2 CCL20 GEM CEBPD EPHA2 MAFK EDN1 RORA NRG1 PURB ANO6	down	***
PODAR_RESPONSE_TO_ADAPHOSTIN_UP	0.0000000	0.0000000	0.8753251	-0.4828402	-2.431938	129	HMOX1 CD55 MIR22HG FYN CD44 BACH1 YPEL5 NCF2 TRIB1 IL23A ANXA1 ADAM17 HSPB1 CSGALNACT2 KLF6 SLC7A11 CLK1 ZEB1 ZFAND5 MAP1LC3B STX3 MAFG ITGAX ATF3 ID2 PNRC1 ZBTB43 CCSER2 DUSP1 PLEK MAFF CREM JUN HSPA1B IFNGR1 PPP1R15A IFRD1 HSPA13 MBNL2 MFAP4 MORC3 SLC3A2 KLF2 DGKG DUSP5 C16orf72 HBP1 GABARAPL1 STX12 RGS2 ZNF267 CLEC2B JUND NEK1 MGAT2 IER5 CDKN1C OSER1 DNAJB9 TNFSF9 ZNF165 ATF4 PMAIP1 RB1CC1 SLC38A2 TUBA1A DNAJB4 DNAJB1 TES FNDC3A WDR26 CCPG1	down	***
WONG_ENDMETRIUM_CANCER_DN	0.0000000	0.0000014	0.7195128	-0.5440852	-2.430241	65	EDNRB TBX3 SFRP4 WNT4 PID1 JPH4 CTSW LDB2 GAS6 LTBP4 MASP1 PEG3 RUNX1T1 KIF26A CNRIP1 RBP7 SYNPO2 HIC1 EHD2 TSHZ3 KLRC2 XYLT1 MME SCARA5 MICU3 LMOD1 PARM1	down	***
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP	0.0000000	0.0000016	0.7195128	-0.5357742	-2.425194	70	CXCL3 IL1B GPR65 PTPRE CD44 AQP9 IDI1 BCL2A1 TRIB1 CASP9 EIF4A1 EIF5 KLF10 PPP2R2A NFE2L2 TFEC MAP2K3 TPP1 CCL3 NFKB1 CXCL2 M6PR PLEK OXSR1 HCAR3 GABARAPL2 SKIL	down	***
ODONNELL_TFRC_TARGETS_DN	0.0000000	0.0000000	0.8870750	0.5702573	2.425161	108	TP63 FOXM1 HELLS KIF20A BUB1B CCNB1 CENPF MND1 NDC80 DEPDC1 DEPDC1B TTK GTSE1 KIF14 ANLN ASPM PLK1 AURKB CENPA ECT2 CDC6 RAD54B MYBL2 PRC1 RANBP1 HMMR CEP55 CHAF1A MKI67 BUB1 TOP2A AURKA RRM2 KIF11 FANCD2 CCDC148 CKAP2L TADA2A NRTN CKS1B CDK1 POLE2 BIRC5 DNA2 MIR3939 DIAPH3 SLC12A1 DLGAP5 TACC3	up	***
ISHIDA_E2F_TARGETS	0.0000000	0.0000001	0.7749390	0.6698702	2.417653	46	TRIP13 CCNB1 UBE2T CDCA7 E2F8 ANLN AURKB PTTG1 CCNB2 PRC1 CDT1 MKI67 BUB1 TOP2A KIF2C RRM2 MCM3 LIG1 DCTPP1 CDKN2C NUSAP1 ASF1B CDK1 DNA2 FEN1 EZH2 CCNE1 TK1 CDC20 RPA1 CCNA2 PRIM1 RAD51 SMC2	up	***
CROONQUIST_NRAS_SIGNALING_DN	0.0000000	0.0000000	0.8140358	0.6177887	2.411982	67	TRIP13 FOXM1 CHEK2 BUB1B CCNB1 NDC80 GINS1 TRAIP STIL PLK1 AURKB CENPA PTTG1 CDC6 TPX2 CCNB2 MCM4 MCM2 MYBL2 ZWINT CHAF1A MKI67 TOP2A AURKA KIF2C MCM7 KIF11 MCM3 CDC25C CHEK1 CKS1B PLOD2 CDK1 SPAG5 KIF22 TK1 POLD1 BRD8 CDC20 HMGA1	up	***
PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN	0.0000014	0.0000364	0.6435518	-0.6167305	-2.411875	36	ADCY9 EMP2 HSPB1 PRELP JAM3 TNS1 CPED1 GRK5 KCNMB1 DSTN MYH11 PTGIS CRIM1 RASL12 PKIG MYLIP ID4 SYNPO2 RABGAP1 PKD2 SOD3 LMOD1	down	***
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN	0.0000000	0.0000000	1.0768682	-0.4311253	-2.407741	282	CD52 RDX GPR65 FYN CTSW ZCCHC2 IDI1 CIR1 CDC42 TGFBR3 EOGT USP47 TGFBR2 ABCB1 CD8A HEG1 GGA2 PTPRM UBL3 CACNA2D2 SERINC1 LUZP1 TOR1AIP1 ADRB2 IL18R1 SLC25A37 CRTAM SRGN CD58 PPP3CC TIPARP EVI2B SRSF5 CASP1 ACSL3 LEPROTL1 ARNTL PTPRC HOPX ID2 CCL4 CEP57 ZBTB43 SS18L2 PRF1 EPS15 CCSER2 KLRD1 CUL5 TBC1D4 DEGS1 USP16 CDKN2AIP NCOA1 ARL6IP5 CREM CD160 KLRB1 PHACTR2 IL2RB CD48 STAT4 ARHGEF10 MTMR9 MCM9 PIK3R1 THUMPD1 IDS MALT1 ENTPD4 TBX21 CEBPZ CST7 ZBED5 SNRK NDUFV2 CALM1 MBP NKG7 TRAPPC10 WHAMMP3 BCAS2 GSAP NR2C1 DUSP5 CNOT7 ATXN1 HNRNPH3 THAP11 ANKRD12 N4BP2L2 CLEC2B PDE4B GTF2B SYT11 HAUS3 INTS6 PCM1 RTN4 IQSEC1 TIAM1 TAB2 PSME4 RBM48 NPAT ANKRD49 B3GNT2 MTUS1 RORA NR3C2 MT2A LPAR6 USP48 PMAIP1 ACAT1 MED17 KLRF1 HAT1 ICOS PPWD1 MICAL1 GNG11 GPR137B DAPP1 ZNF14 CTR9 MAN1A1 TES CUL2 RCBTB2 TAF1D FCHSD2 NKTR APOBEC3C DERL2 CFLAR PJA2 GZMB TPST2 SLC25A28 KLRC1 MT1X	down	***
AMIT_DELAYED_EARLY_GENES	0.0000047	0.0001094	0.6105269	-0.7376069	-2.401529	18	FOSL1 BTG2 KLF10 KLF6 RBMS1 ATF3 HES1 MAFF PIAS1 CREM JUNB	down	***
PID_IL12_STAT4_PATHWAY	0.0000037	0.0000874	0.6272567	-0.6394252	-2.400658	30	PPP3CA IL18R1 PRF1 CD80 JUN STAT4 TBX21 FOS MAPK8 TGFB1 CD86 PPP3R1 IL18 IL18RAP CREBBP CD3G PIAS2 HLA-DRB1 CD3E IRF1 CD4	down	***
BENPORATH_PROLIFERATION	0.0000000	0.0000000	0.8986712	0.5451297	2.387304	136	NEK2 CENPF UBE2T GGCT MND1 PBK NDC80 PRIM2 CDCA7 TTK RACGAP1 ANLN ASPM NUF2 CENPA PTTG1 CCNB2 MCM2 TYMS MYBL2 PRC1 DTL SRPK1 AVL9 CDT1 RANBP1 EXO1 BUB1 FANCA TOP2A AURKA RRM2 CDCA5 PDCD5 RAD54L GPSM2 MCM3 CHAF1B KDELR2 MAD2L1 RAD51AP1 PKMYT1 IDH2 PARP1 PPIL1 KNSTRN CKS1B CDK1 BIRC5 C1orf112 NCAPG EZH2 SPAG5 ILF2 CTSV DTYMK CSNK1G1 S100A9 DAP3 MAGOHB DCUN1D5 CENPM SNRPD1 GINS3 PSMB4 ATAD2 SUV39H2 PRPF18 MSH2 FAM3C	up	***
FUJII_YBX1_TARGETS_DN	0.0000000	0.0000000	1.0073180	0.5306475	2.385461	176	DKK1 TRIP13 PTGES FOXM1 HELLS MDM1 PARPBP MCM10 FANCI BUB1B TIMELESS TTF2 DEPDC1 BRCA1 DEPDC1B CDCA7 ASPM CDC6 FIGNL1 UHRF1 MCM4 MCM2 RAD54B CDC25A MYBL2 CCNF DTL ZWINT CDT1 CASP2 MELK EXO1 KIF23 CHAF1A TOP2A CCT5 ODF2 POLA2 MCM7 RRM2 PRKDC KIF11 FANCD2 MCM3 LMNB1 CDC25C LIG1 CHEK1 MAD2L1 BRIP1 SKP2 CKS1B NCAPG2 NUSAP1 ASF1B DMKN POLE2 UNG BPGM NEIL3 FEN1 METTL3 CBX1 MAD2L2 RNASEH2A CDC23 SLC26A2 UBAC1 TRIO SSRP1 TK1 DTYMK DBN1 ENAH MSI2 GINS2 SPA17	up	***
KAMMINGA_EZH2_TARGETS	0.0000000	0.0000014	0.7195128	0.6835806	2.384625	38	NEK2 CDCA7 AURKB ECT2 CCNB2 MCM4 MCM2 PRC1 MKI67 TOP2A AURKA CDCA5 SETDB1 MCM3 TOPBP1 MAD2L1 AHCY NUSAP1 POLE2 GMNN	up	***
WONG_EMBRYONIC_STEM_CELL_CORE	0.0000000	0.0000000	1.1421912	0.4956850	2.381378	303	TRIP13 HELLS KIF20A RUVBL1 AK4 ELOVL6 CHEK2 BUB1B NUP107 PROM1 NEK2 SOX2 SLC2A1 THOC3 NDC80 PRIM2 CDCA7 TTK CDK4 RACGAP1 GTSE1 NIPSNAP1 PLK1 CDCA8 AURKB CDC6 E2F3 CCNB2 MCM4 MCM2 MYBL2 GLDC ORC1 CCNF ALDOC DTL NCAPD2 COQ3 LSM5 RUVBL2 NDUFB8 EXO1 CISD1 KIF23 CHAF1A MRPL15 BUB1 EEF1E1 TOP2A CCT5 AURKA CBX3 NDUFS2 MCM7 RRM2 CDCA5 WDHD1 KIF11 MCM3 LMNB1 CHEK1 MAD2L1 FBL GNPDA1 ETFA RAD18 IPO9 BLM MRPS30 PHB UQCR11 PARP1 CKS1B NUSAP1 MRPL37 CDK1 POLE2 BIRC5 GMNN POLR3K PSMB5 MRPS2 SPAG5 NLN NOP2 PA2G4 EIF6 DNMT1 VBP1 DPP3 DLGAP5 NDUFA11 PSMA5 PUS1 ALDH7A1 SNRPA KIF22 MRPL11 MAPK13 DTYMK HDAC1 MRPL4 ANP32E DAP3 POLD1 CDC7 GEMIN6 TIMM13 CDC20 STOML2 POP7 FAM136A UBE2V2 PRMT1 CKAP2 MCM5 SNRPD1 RCC1 PDIA4 LSM4 NT5DC2 EIF3K RAB34 FARSA GLO1 MSH2 CCNA2 PRIM1 BANF1 NME4 WDR77 COX5B TRIP6 ECHS1 GNA14 SMC2 TP53 TIMM44 APEX1 ENO1 NDUFB7 ACAD8 BRIX1 NCAPH GEMIN2 LYPLA1 RCN2 MRTO4 PLK4 UTP18 MRPL12 ADSL CLPP	up	***
VILLANUEVA_LIVER_CANCER_KRT19_UP	0.0000000	0.0000000	0.9214260	0.5399867	2.380832	148	KIF20A HJURP MCM10 FANCI GABRB3 C2CD4A TROAP DROSHA JPH3 NDC80 DEPDC1B GAL3ST1 TTK GINS1 ANLN STIL CDCA8 PTTG1 ECT2 SOX9 TPX2 CDC25A COL22A1 MCM8 ZWINT AP1G2 SIPA1L3 CASP2 MELK KIF23 CEP55 MKI67 KIF15 KNTC1 BUB1 TOP2A SFI1 KIF2C RAD54L GPSM2 LMNB1 SOX4 CKAP2L CENPO RAB13 BLM ZNF605 DHRS13 NCAPG DNA2 EZH2 GOLGA3 ZNF354A DCLRE1C DLGAP5 MAPK13 SALL4 ZNF300 KIF20B CDC7 NR6A1 CDC20 CENPM	up	***
WILENSKY_RESPONSE_TO_DARAPLADIB	0.0000075	0.0001647	0.6105269	-0.6817038	-2.376210	23	IL1A HMOX1 PLA2G7 GM2A LAIR1 EVI2B PTAFR PLAUR EVI2A CTSS CD48 BIN2 CCR1 ARRB2	down	***
APPEL_IMATINIB_RESPONSE	0.0000056	0.0001285	0.6105269	-0.6323921	-2.374253	30	ACP5 PPARG ENG C5AR1 FUCA1 LAMP1 LILRB3 APOD ASAH1 GM2A APOC1 MSR1 CTSD HEXB CTSZ	down	***
REACTOME_NGF_STIMULATED_TRANSCRIPTION	0.0000030	0.0000720	0.6272567	-0.6146539	-2.370655	34	LYL1 EGR2 FOSL1 TRIB1 REST ID3 ID2 ARC SRF ID4 SGK1 JUNB CREB1 FOS FOSB NAB1 JUND VGF EGR1 ATF2 EP300 MEF2D	down	***
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN	0.0000000	0.0000011	0.7337620	-0.5164452	-2.366015	78	CXCL3 CD300LF IL1B LIPA TRPV2 LPL EGR2 SAMHD1 MYADM AQP9 C5AR1 SLC11A1 FGR ANXA1 CLEC7A BTG2 LITAF SIRPA MCL1 MSR1 MPEG1 KLF4 DAB2 STX3 GRK5 ID2 DUSP1 PLEK CPT1A HCK CTSS MITF FOS CHIA EHD1 FPR2	down	***
WU_APOPTOSIS_BY_CDKN1A_VIA_TP53	0.0000000	0.0000006	0.7477397	0.6384511	2.357323	51	FANCI FAT2 ZNF84 CCNB1 UBE2T PBK TTK RACGAP1 ANLN ASPM AURKB TPX2 MCM4 MCM2 TYMS PRC1 SPDL1 EXO1 CEP55 MKI67 KNTC1 BUB1 AURKA WDHD1 MCM3 CDK1 NCAPG HMGB1P5	up	***
KAUFFMANN_MELANOMA_RELAPSE_UP	0.0000000	0.0000003	0.7614608	0.6264929	2.356837	57	CDC45 CHEK2 CENPF POLQ BRCA1 PTTG1 CDC6 MCM4 XRCC2 EXO1 CHAF1A FANCA TOP2A EME1 MCM7 RRM2 RAD54L FANCD2 MCM3 CHEK1 ORC6 MAD2L1 RAD51AP1 BRIP1 RAD18 BLM GMNN NEIL3 FANCG GINS2 MCM6 TDP1 MSH2 RFC5 RAD51 SMC2 PPIA	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP	0.0000063	0.0001406	0.6105269	-0.6402797	-2.352068	27	LINC00622 LATS2 KLF6 CSRNP1 ZSWIM6 MAFG RIT1 MAFF DNAJA1 PPP1R15A PTP4A1 KIAA0232 ZNF844 C16orf72 GABARAPL1 ABL2 FBXO30 HSPA8	down	***
AMIT_EGF_RESPONSE_120_HELA	0.0000004	0.0000124	0.6749629	-0.5423752	-2.348022	60	SOWAHC BDNF FOSL1 CDC42EP2 CLCF1 HBEGF NDEL1 MCL1 FOXC2 MAP2K3 ARRB1 SNAI1 BIRC2 PLAUR CDKN1A CXCL2 MATK MAFF AREG TNFRSF10B RUNX3 MARC2 IRS2 TAGLN JUND GEM IER5 EPHA2 CYTH1 HNRNPH1 PUS3 DUSP6	down	***
NIKOLSKY_BREAST_CANCER_7P22_AMPLICON	0.0000001	0.0000028	0.7049757	0.6867793	2.347795	35	SLC29A4 IQCE EIF3B INTS1 MICALL2 NUDT1 BRAT1 TMEM184A GPER1 MAD1L1 WIPI2 GPR146 GET4 C7orf50 COX19 CYP2W1 TTYH3 SUN1 ADAP1 AP5Z1 PSMG3 TNRC18 FOXK1	up	***
CHUNG_BLISTER_CYTOTOXICITY_DN	0.0000013	0.0000349	0.6435518	-0.5913569	-2.345591	39	MNDA PRAM1 FBXO3 C12orf76 FOXP1 KIAA0513 SELL GCA SNN MTPN SNAP23 RGS18 CSTA PLCG2 BIN2 PDLIM1 KAT2B RBL2 FKBP1A CDC42EP3 P2RX1 GRB10	down	***
REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION	0.0000003	0.0000099	0.6749629	-0.5555946	-2.344341	54	LYL1 EGR2 FOSL1 MEF2A TRIB1 DUSP3 REST ID3 ID2 ARC SRF RPS6KA2 ID4 PPP2CA SGK1 JUNB CREB1 RPS6KA1 FOS FOSB PPP2CB NAB1 JUND VGF DUSP7 EGR1 DUSP6 ATF2 MAPK1 EP300 MEF2D MAPK7	down	***
NADERI_BREAST_CANCER_PROGNOSIS_UP	0.0000000	0.0000014	0.7195128	0.6553061	2.341002	43	KIF20A TIMELESS UBE2T NDC80 RACGAP1 FA2H ASPM CDCA8 PTTG1 UHRF1 MYBL2 SHMT2 MELK EXO1 CEP55 BUB1 CDCA5 IL20RB RNFT2 SOX11 DSCC1 SPAG5 FADD TRIM24 POLD1 PSMD2	up	***
SWEET_LUNG_CANCER_KRAS_DN	0.0000000	0.0000000	1.1330899	-0.4113556	-2.340629	349	SMAD6 EPAS1 PRX ACVRL1 SC5D SASH1 FOXF1 TEK ACE EDNRB RASIP1 TBX3 IL1B MNDA CLEC3B TIE1 LYVE1 EMP2 GREM2 CYP4B1 RAMP2 THBD PTPRB CDH5 ENG BDNF LYL1 FYN EMCN LMO2 SOX17 CCRL2 KANK3 CAV1 CALCRL QKI INPP5A MSLN SPCS3 NUMB TBX2 LTBP4 TM2D3 LIFR LATS2 PAG1 MS4A1 ADRB2 CD93 SPTBN1 CES1 ZEB1 SRGN TFRC KRT4 RHOB ADARB1 CFD ARRB1 TNNC1 RAB12 AHNAK SORBS1 NPNT KLF4 PEG3 ID3 KLF9 ANKRD10 TJP1 CLDN5 GRK5 KLF7 MYO1B CLIC4 NPR3 CADM1 HOPX RECK IGFBP2 SHE EPS15 DUSP1 MYH11 PTGIS PLAC9 VWF SIAH1 HCK VAMP3 SCEL FLT1 METAP1 JUN SH3BP5 INMT KCTD12 ETS1 CYP2A6 RHOJ FERMT2 ACKR3 GMFG PRKCE NDST1 CDK14 ACSL1 KLF2 BCL6B ICAM2 PKD2 SLC4A5 PKIA TCF4 PDLIM1 GNB4 MEIS1 MACF1 RGS2 SPOCK2 TAGLN ETS2 SOD3 SESN1 GPX3 SPARCL1 TFPI SCN7A SPIB MS4A4A TIAM1 CXCR4 CDKN1C MFAP5 PTCH1 POLR2M GLUL LIMCH1 NFKBIA KIT TIMP3 EDN1 COL13A1 GIMAP4 FEZ2 PAPSS2 PPP1CB MAP4 PSIP1 KALRN PPP2R3C	down	***
LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN	0.0000000	0.0000001	0.8012156	-0.4694866	-2.333610	118	SLC31A2 DPYSL2 LINC00472 LMO2 PSMD5 TMX4 PBX3 ANXA5 RAB14 RHOB CYBRD1 PER3 SDCBP AOC3 AFAP1L1 DAB2 ZFAND5 CLIC4 UBQLN1 ERP44 UBE2E2 CD302 EVI2A GNAQ BACE1 VCPKMT TMOD1 SGK1 SOCS3 PPP6C MT1L CCDC50 AK1 RCAN1 GLIPR1 CELF2 TGFB1 CTNNAL1 GABARAPL1 RIMKLB MBNL1 BMP2K MS4A4A ALDH2 ISCU OSER1 RASSF8 RNF38 DNAJB9 MT2A TOX2 LYZ SLFN11 SETX PSIP1 CFL2 TGOLN2 FBXW2 ALG2 MSANTD3 MT1E TES NFIL3 DUSP22 MYO5A MT1X GSN SON C3AR1 ISCA1	down	***
PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP	0.0000002	0.0000079	0.6749629	-0.5604649	-2.331019	51	ACP5 SLC39A8 FUCA1 LAMP1 PLA2G7 ATP2B1 GM2A IFI30 RGCC GRN SRGN MPEG1 DAB2 RBMS1 CXCL2 PLEKHB2 NCKAP1L SGK1 CTSS RAPGEF1 SIGLEC15 TRAK2 SOD2 MS4A4A GLUL SAMSN1 CREG1 PAPSS2 CSF2RB DUSP6	down	***
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN	0.0000000	0.0000000	1.0276699	-0.4135388	-2.322442	287	CXCL3 EREG CD52 FCN1 PHACTR1 PECAM1 OSBPL1A CD55 IL1B LTA4H FBP1 CYP27A1 SNX10 LPXN PID1 FYN LY86 LMO2 CCRL2 AQP9 MYD88 C5AR1 NEDD9 LAMP1 EPB41L3 TEX2 TMX4 CCNL1 DPEP2 PLA2G7 MCTP1 HBEGF SLC7A7 ASAH1 ENTPD1 ANXA5 KLF10 LAIR1 RGCC CRTAM CES1 TCF7L2 MCL1 FBXL5 CFD TLE4 CASP1 KLF9 DAB2 ZFAND5 STK17B DENND3 MYO15B ITPK1 CTSD CCL3 CTBS SELL TM6SF1 DNTTIP2 PINK1 ZNF706 HLA-DQA1 MAPRE2 NCOA1 HEXB SGK1 CD48 C1QA MITF SH3BP5 TREM1 TMEM251 ZNF804A PTGER2 ATP13A3 CXCL5 PPM1F RHOQ PELI1 ICAM2 NKG7 RIN2 EMC7 TIMP2 CHPT1 TFEB TSC22D1 GALC APLP2 SOD2 LGALS3 CCR1 DECR1 RGS2 ETS2 RNF138 IL18 CCDC69 SLC31A1 CALHM2 MS4A4A CDKN1C SIK3 NLRP3 TBC1D1 ICAM3 FDX1 BCAT1 NRG1 MT2A SFPQ MIS18BP1 GRPEL1 ARFGAP3 CACNA2D3 ACAT1 SPHK1 DMXL2 ATP6V0A1 HERPUD1 EGR1 BHLHE41 DUSP6 NR4A2 CX3CR1 CLEC4E AOAH ITGAL FPR1 ZFP36	down	***
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN	0.0000000	0.0000000	1.0574636	0.4899864	2.320774	271	ATP10B CCNO SAA1 LTF ALDH3B2 PRR15 RIBC2 ABCA13 MUC13 ADH1C DNAH2 CHST6 PROM1 ARMC3 PTPRN2 MUC4 WFDC2 TOX3 MUC16 TTC25 CCDC113 TFF3 FANK1 CCDC74A LCN2 ALDH1L1 SLC27A2 RHOV DAW1 SPAG17 AGR2 CIB1 MUC20 VILL DNAI1 TJP3 RSPH1 ARMC4 C9orf116 FOXJ1 TSGA10 BPIFB1 IQCD PSENEN SLC2A10 P4HTM HYDIN WDR78 SPEF2 TEKT2 FAM216B SRGAP3-AS2 CCDC114 C7orf57 WDR66 NEK11 PDZK1IP1 ASS1 IFT172 BACE2 SPATA17 CAPS FUT2 MGLL TTC9 DRC1 DNER DMKN TNFRSF21 MDH1B WDR54 FAM81B SPAG6 KLHDC9 NEK5 EFCAB1 TRIM7 KIAA1211L AK7 DNAH5 TMEM231 CASC1 TSPAN1 PIAS3 DNAH7 SPATA18 EFCAB2 TUBB2A FAM166B IQCG FBXO15 MORN2 S100A9 SPAG1 SPA17 SMIM22 AHNAK2 EPB41L4B TRAF3IP1 AGBL2 EFHC1 RSPH10B CXCL1 UPK1B EML6 ODF3B VWA3B DNAI2 EFHB KATNB1 RSPH4A TMEM45B B9D1 LRP11 C19orf33 TTC12 TMC5 SYBU CCDC181 TUBA4B ENKUR TCTEX1D1 TRAK1 LRG1 CGN UBXN10 ALOX15 CAPN9 CLDN10 MUC1 MAP3K19 NQO1 TEX9 SPATA33 ARMC2 MORN3 DNAAF1 TEKT1 WDR63 ST6GALNAC1 ROPN1L TMPRSS4 RALGPS2 PTGR1 AK9 TCEA3 SNTN TPPP3 OSCP1 C1orf194 ELL3 TPPP VWA5A S100P CCDC65 C5orf49 DNAH9 FMO5 PACRG PIFO	up	***
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP	0.0000000	0.0000011	0.7337620	-0.4925740	-2.312985	88	CSDC2 CYP4B1 TXNIP TMEM204 BTG2 RGCC TCAP MCL1 CNN1 TIPARP NES KLF9 ZFAND5 DOCK9 CDKN1A ATF3 PER1 MAPRE2 PDK4 ELF1 AREG JUN PIK3R1 MFAP4 FSTL3 KLF2 FOXO3 FLNC CDC37L1 IRS2 AMD1 IER5 CEBPD DIXDC1 MT1M METTL7A GLUL NFKBIA TIMP3 SYNPO2L MT2A DNAJB5 SERPINE1 ZBTB16 SLC38A2 ZFP36 MT1E NFIL3 SH3BGR PLA2G5 MT1X CDC42EP4	down	***
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	0.0000000	0.0000000	0.8513391	0.5309800	2.312851	132	TRIP13 HELLS KIF20A HJURP CDC45 MCM10 NEK2 COIL CCNB1 UBE2T NDC80 TTK RACGAP1 E2F8 ANLN AURKB CENPA ECT2 CCNB2 PRC1 ACY1 SPDL1 MELK KIF23 MKI67 BUB1 TOP2A CENPL AURKA KIF2C RRM2 CDCA5 WDHD1 RAD54L CHAF1B CDC25C LIG1 DCTPP1 PIH1D1 INCENP CKS1B CDKN2C NUSAP1 CBX5 CDK1 DNA2 FEN1 SSX2IP CBX1 VPS72 DNMT1 CCNE1 DLGAP5 KIF22 TK1 ANP32E CKAP5 CDC20 RPA1 MCM6 HAUS6 MYEF2 NT5DC2 CCNA2 RFC5 RAD51	up	***
CAIRO_HEPATOBLASTOMA_CLASSES_UP	0.0000000	0.0000000	1.3267161	0.4633739	2.308844	536	HMGA2 TRIP13 KIF20A HJURP RUVBL1 AK4 MCM10 FANCI CHEK2 BUB1B NEK2 COIL SULT1C2 CCNB1 CENPF TIMELESS CPSF6 PSPH GGCT PBK KIF18B NDC80 TBRG4 TTK GINS1 CDK4 KIF14 ASPM TOMM34 PLK1 CDCA8 AURKB CENPA ALDH18A1 ECT2 CDC6 TPX2 CCNB2 MCM4 MCM2 CDC25A PRC1 GLDC CCNF EIF3B DTL CCT6A LIG3 MIS18A GINS4 SRPK1 NCAPD2 MYL6B CDT1 AP1G2 CCT2 SPDL1 NME1 RANBP1 RUVBL2 BZW2 HMMR NLE1 SMARCC1 KIF23 OSBPL2 CHAF1A MKI67 KIF15 MRPL15 KNTC1 BUB1 FANCA EEF1E1 TOP2A CCT5 RFXANK PUS7 AURKA CBX3 WDR3 ODF2 SAE1 SFI1 KIF2C MCM7 MAD1L1 RRM2 PRKDC TRRAP KIF11 MCM3 PLTP CDC25C EMG1 YEATS2 LIG1 CHEK1 DNAJC9 MAD2L1 AHCY FBL RAD51AP1 CAD PHB MNAT1 SKP2 PARP1 DDX56 CKLF NCAPG2 NUSAP1 CDK1 EXOSC2 RFWD3 BIRC5 CCT3 ATIC NPM3 NCAPG TRAP1 PSMB5 SEC61G PRPF6 CPNE1 EZH2 NUP205 POLR1C ACTR3B SPAG5 SF3B3 FOCAD LAPTM4B RNASEH2A DNAJC7 KPNB1 TPD52L2 CHCHD2 DNMT1 ILF2 CCNE1 TUBG1 DLGAP5 PDCD11 TRMU CTSV PUS1 AARSD1 MAN1B1 KIF22 SSRP1 DTYMK MYBBP1A CENPQ GINS2 AGPAT5 TCEA1 KRT19 POLD1 NUP85 AAMP CCT7 SUPT16H PFAS CKAP5 CDC20 STOML2 HMGA1 LRRC59 POP7 FAM136A ACLY MCM6 DNMT3A MRPS33 THOC5 PRMT1 UTP20 HEATR1 TDP1 SNRPD1 LANCL2 SRSF1 C1orf109 AATF CREB3L2 POLR3E RCC1 PDIA4 LSM4 TXNL4A PI4KA NT5DC2 ERGIC3 WDYHV1 TSR1 TCERG1 PRMT5 EPCAM KLHL7 DPH5 FARSA COG5 PMS1 B9D1 ATP6AP1 MSH2 CCNA2 SMARCA4 HDLBP GTF3C2 ABCF2 WDR77 STK25 TPGS2 ZWILCH SUPT3H PAXIP1 SNRNP200 ACP1 AGBL5 CIAPIN1 SMC2 PNKP GMPR2 DNAJC10 GPX7 APEX1 MRPS27 UBE2C GPN1 CDKAL1 ENO1 NUP210 SMARCB1 RRS1 NAT10 PLIN3 NUP93 CALU DDX41	up	***
LIAN_LIPA_TARGETS_3M	0.0000009	0.0000244	0.6594444	-0.5496991	-2.305963	50	CXCL3 ACP5 HMOX1 MS4A7 FCN1 SLC15A3 MARCO SLC11A1 IGSF6 LILRB3 PLA2G7 MSR1 MPEG1 ATP6V0D2 FCER1G MMP19 KLRB1 UTRN C1QA CSTA	down	***
FINETTI_BREAST_CANCER_KINOME_RED	0.0000006	0.0000173	0.6594444	0.8039540	2.292695	16	BUB1B NEK2 PBK TTK PLK1 AURKB SRPK1 MELK BUB1 AURKA CHEK1 CDK1	up	***
MARSON_BOUND_BY_E2F4_UNSTIMULATED	0.0000000	0.0000000	1.3188888	0.4585531	2.285862	537	DDX11 CEP72 SPICE1 HELLS KIF20A MDM1 HJURP CDC45 PARPBP MCM10 FANCI CHEK2 BUB1B NUP107 NEK2 CCDC34 DROSHA POLQ C21orf58 MND1 PBK KIF18B NDC80 PRIM2 DEPDC1 PIF1 DEPDC1B CDCA7 TTK CDCA2 AGFG2 RACGAP1 GTSE1 ANLN TRAIP ASPM NABP2 STIL FLAD1 DGCR8 PLK1 NUF2 IFT27 CDCA8 AURKB CENPA ECT2 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 CDC25A MYBL2 PMS2 PRC1 XRCC2 ORC1 CCNF DTL C19orf57 MCM8 MIS18A NCAPD2 CDT1 SPDL1 LSM5 CXCL10 CCDC150 MELK HMMR EXO1 KIF23 CEP55 RND2 HLTF KIF15 AP4M1 BUB1 FANCA TOP2A AURKA EME1 CBX3 SAE1 POLD2 KIF2C POC1A CLSPN RRM2 CDCA5 PRKDC CDNF RAD54L MRPL27 KIF11 PASK MCM3 CDC25C AIMP2 SARS2 ABCB6 TOPBP1 CHEK1 DNAJC9 ORC6 CC2D1A CKAP2L NFYA RAD51AP1 TIMM50 TRMT2A SPC24 DSCC1 BRIP1 BLM PML SKP2 INCENP POLN KNSTRN EFCAB11 NUSAP1 ASF1B CDK1 POLE2 EXOSC2 CENPH BIRC5 CCM2 C1orf112 NUDT2 TYW1 E2F1 UNG CMTR1 NEIL3 FEN1 EZH2 SPAG5 MRPS12 OARD1 TTI1 MTBP CBX1 DIAPH3 RECQL4 MAST1 CENPP C9orf43 KPNB1 RANGAP1 NET1 DNMT1 PARS2 FANCG PELP1 INTS7 DLGAP5 TACC3 MNS1 KIF22 CHTF18 STOML1 ESCO2 ANP32E C15orf41 NUP85 MAGOHB CEP128 RAB24 CDC7 CENPK SASS6 GEMIN6 BRD8 CDC20 RPRD1B PALB2 CENPM YLPM1 AAAS UBXN6 RPUSD1 FANCM CDK5RAP2 MCM6 XRCC4 MCM5 CD2BP2 TDP1 HAUS6 C5orf22 TFAP4 SRSF1 C1orf109 GINS3 STMN3 KATNB1 AP4B1 STK35 TCERG1 ALG8 LRRC14 ALMS1 MSH2 CCNA2 PRIM1 DZIP3 PRR11 RTEL1 SHCBP1 PAK4 ABHD10 RAD51 TRIP4 ZWILCH ARHGAP11A KIAA0825 NME7 WDR76 MXD3 SMC2 TONSL XPC CENPE TCF3 C1orf159 SMPD4 TP53 PAICS UBE2C NCAPD3 RAD1 RRS1 ZNF367 TTLL5 KIF24 CALU SART3 BRIX1 C12orf10 SETD5 NCAPH ALKBH2 LMBRD2 TFB1M CSTF1	up	***
NIKOLSKY_BREAST_CANCER_5P15_AMPLICON	0.0000008	0.0000218	0.6594444	0.7470803	2.285353	21	SLC9A3 TRIP13 CEP72 PDCD6 CCDC127 NDUFS6 PLEKHG4B SLC6A3 EXOC3 CLPTM1L SDHA SLC12A7 BRD9 MRPL36	up	***
PLASARI_TGFB1_TARGETS_1HR_UP	0.0000239	0.0004705	0.5756103	-0.5924109	-2.282989	32	EGR2 HBEGF KLF10 NR4A1 ZMIZ1 CSRNP1 SNAI1 ID2 SMAD7 HES1 WNT9A ID4 IL6 JUNB IER5 SPATA13 SPSB1 SERPINE1	down	***
RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP	0.0000013	0.0000343	0.6435518	-0.5073091	-2.281725	66	SWAP70 CD55 MNDA GPR65 MIR22HG LY86 TXNIP ASAH1 MAP3K8 MS4A1 AHNAK KLF9 GRK5 LY96 PTPRC CA1 AREG CREM DDX17 IFNGR1 CSTA GLIPR1 GPR183 IDS RGS13 PELI1 CHPT1 DUSP5 GABARAPL1 RGS2 GPR18 IQSEC1 GLUL ZNF165 LYZ NR4A2 S100A8	down	***
ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN	0.0000002	0.0000058	0.6901325	0.6496284	2.272979	39	FOXM1 HELLS BUB1B CCNB1 CENPF MND1 DEPDC1 DEPDC1B AURKB CDC6 MYBL2 RANBP1 CHAF1A TOP2A AURKA CKS1B CDK1 POLE2 BIRC5 DNA2	up	***
MORI_IMMATURE_B_LYMPHOCYTE_UP	0.0000065	0.0001446	0.6105269	-0.5683281	-2.271469	41	GPR65 SAMHD1 GPCPD1 GGA2 IFI30 MS4A1 MCL1 LIMS1 PTPRC HCK BTG1 CTSS ATP6V0B CD83 PXK RHOQ MYL12A CD74 IGKV1D-39 PIP4K2A CNR2 DUSP6	down	***
DIRMEIER_LMP1_RESPONSE_EARLY	0.0000009	0.0000260	0.6594444	-0.5313611	-2.270271	58	INSIG1 EGR2 BCL2A1 IER2 MAN2B1 EIF1 BTG2 KLF6 LCP1 MCL1 CCL3 CCL4 JUN JUNB PPP1R15A ACKR3 CD83 GPR183 DUSP5 JUND ICAM1 ACTB TRAF1 NFKBIA TNFSF9 HERPUD1 EGR1 HMGCS1 ZFP36 PIK3CG CD69	down	***
PATIL_LIVER_CANCER	0.0000000	0.0000000	1.3110148	0.4534307	2.267873	576	TSPAN8 DKK1 TRIP13 ONECUT2 ONECUT1 DDX11 FOXM1 HELLS DDX12P HJURP CPLX2 CDC45 TROAP NEK2 BAIAP2L2 CENPF IGF2BP3 FLVCR1 UBE2T PSPH PBK CLGN PRIM2 DEPDC1B CDCA7 LCN2 CDK4 CCDC14 TRAIP SPP1 MSTO1 COL7A1 FLAD1 AP1S1 BAIAP2L1 PLK1 NUF2 CDCA8 PTTG1 ALDH18A1 ESPL1 CDC6 TPX2 E2F3 MCM4 SPATS2 PRKCA TYMS CDC25A MYBL2 AACS DTL GON4L XPO5 LIG3 MIS18A XPOT ZWINT CLPTM1L ITGA2 OSBP2 CASP2 HMMR NUDT1 KIF23 CEP55 CHAF1A CUL7 HLTF RNF216P1 TP53BP1 KNTC1 RHNO1 PAFAH1B3 BUB1 TOP2A CCT5 AURKA NUP155 HHAT YKT6 TPR E2F2 CENPW MPHOSPH9 CPD RRM2 CDCA5 PRKDC RHOBTB3 RNF43 KIF11 GPSM2 MCM3 PLTP HORMAD1 CD24 SLC9A3R1 CHEK1 MAD2L1 NFYA ZKSCAN1 PKMYT1 PTGFRN FADS2 TTYH3 ALDOA DLG5 SKP2 CKLF KNSTRN ZNF512B CKS1B NCAPG2 CDKN2C HPS4 FASTK NUSAP1 TMEM106C ASF1B PAK1 CDK1 ARHGAP39 CEP97 CENPJ DIDO1 UCK2 ZNF652 GMNN RBCK1 E2F1 PRPF6 LARP1 PEG10 FEN1 CPNE1 EZH2 NUP205 TAF6 LRRC42 PLCG1 SNRPE CBX1 VPS72 RECQL4 LAPTM4B UBN2 LGR5 FANCG GRAMD1A INTS7 ILF2 CEP192 POFUT1 RHOC TRIM24 TUBG1 COL1A2 GNPAT DLGAP5 SMG5 SNX27 SLC26A2 LMNB2 DVL3 TRIO PTGES2 COL5A2 DUSP12 RBM12B TMEM237 UBE2Q1 PPOX TK1 ENAH CENPQ RHBDD3 SCN8A JMJD4 ESCO2 LMTK2 TCEA1 XPR1 KIF20B C15orf41 TSEN54 POLD1 C12orf73 ENPP2 CABLES2 LSM14B ETV4 RNF187 SUPT16H KDELR3 KLHL23 CDC20 CENPM KIAA0100 TUBG2 ZCCHC17 HMGA1 AP3M2 FAM136A ACLY MCM6 MYPOP DNMT3A MYO5C THOC5 ANKIB1 MCM5 USP21 MALSU1 PYGO2 DUS4L CREB3L2 LSM4 SH3PXD2B TMEM45B STK35 ATAD2 INTS8 CEP85 RER1 ATP6AP1 MCRS1 CCNA2 BBX CAP2 RNF157 LPGAT1 ZWILCH RDH10 TYSND1 TARBP1 SOX12 RPRD2 F13A1 PTPRF UBAP2L ARHGEF39 GNA12 RNF213 ADAM15 KIAA1522 KDM5B HGS SLC36A1 CDC25B UBE2C CYSTM1 LINC00205 FBXO45 BCAT2 TMEM98 BTN2A1 RAD1 SLC39A1	up	***
MANALO_HYPOXIA_DN	0.0000000	0.0000000	0.9969862	0.4803210	2.267066	263	TRIP13 DDX11 HJURP RUVBL1 PARPBP MCM10 FANCI ELOVL6 PAIP1 PBK TSFM BRCA1 MRPL46 GINS1 NOL12 STIL CDC6 TPX2 MCM4 MCM2 UMPS FERMT1 PRC1 CCNF ZWINT SPDL1 NME1 RANBP1 TTLL4 MELK EXO1 CISD1 NLE1 KIF23 CHAF1A RPL39L EEF1E1 POLA2 POLD2 MPHOSPH9 RRM2 RBM28 AKAP1 MCM3 AIMP2 EMG1 DNAJC9 ORC6 MAD2L1 RAD51AP1 PKMYT1 CAD GNPDA1 PHB RGS4 SLC25A10 SKP2 PARP1 NUSAP1 ASF1B CDK1 POLE2 EXOSC2 C1orf112 ATIC GMNN POLR3K DNA2 FEN1 NUP205 MRPS12 PA2G4 FAM86C1 FANCG TELO2 CCNE1 TUBG1 SCLY PUS1 LMNB2 MNS1 POMT2 GINS2 PRMT7 NUP85 CDC7 NIF3L1 GEMIN6 PFAS DGCR11 HMGA1 RRP9 POP7 FAM136A SRRT MCM6 METTL2B UTP20 MCM5 HEATR1 SNRPD1 DDX23 NEK4 GINS3 URB1 SLC1A5 TSR1 PRMT5 CCNA2 SHCBP1 RFC5 AMDHD2 TUBGCP4 USP39 ABCF2 WDR4 WDR77 RAD51 ZWILCH RSAD1	up	***
FISCHER_DREAM_TARGETS	0.0000000	0.0000000	1.5565442	0.4474023	2.266585	841	TRIP13 DDX11 FOXM1 CEP72 HELLS KIF20A MDM1 HJURP CDC45 TICRR PARPBP MCM10 FANCI ZNF273 TROAP CHEK2 BUB1B NUP107 NEK2 CCNB1 CCDC34 CENPF TIMELESS POLQ UBE2T GGCT MND1 PBK KIF18B TTF2 NDC80 PRIM2 DEPDC1 PIF1 TBRG4 BRCA1 THEM4 DEPDC1B CDCA7 ZNF138 TTK GINS1 CDCA2 CDK4 RACGAP1 IQGAP3 E2F8 GTSE1 DBF4B KIF14 ANLN CCDC14 TRAIP DNMT3B POLE ASPM STIL DGCR8 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 ZNF714 UHRF1 KNOP1 MCM4 SPATS2 MCM2 RAD54B CDC25A MYBL2 PRC1 XRCC2 ORC1 CCNF EIF3B DTL MCM8 MIS18A GINS4 CAND1 SHMT2 NCAPD2 ZWINT CDT1 ZNF107 SPDL1 TRIM45 LSM5 HAUS5 RANBP1 WDR62 C5orf34 TTLL4 CASP2 CCDC150 MELK HMMR EXO1 NUDT1 C19orf48 SMARCC1 KIF23 CEP55 CHAF1A RPL39L MKI67 HLTF KIF15 KNTC1 RHNO1 PAFAH1B3 BUB1 FANCA CCDC77 AUNIP TOP2A EXOC4 CCT5 CENPL AURKA EME1 NUP155 CBX3 ODF2 POLA2 SAE1 POLD2 GTPBP3 KIF2C MCM7 E2F2 CENPW POC1A CLSPN RSRC1 MPHOSPH9 RRM2 MMS22L CDCA5 PRKDC WDHD1 RAD54L MRPL3 KLHDC4 ZNF146 KIF11 PASK FANCD2 GPSM2 MCM3 LMNB1 CDC25C EMG1 ZNF530 TOPBP1 CHEK1 DNAJC9 ORC6 ACTL6A MAD2L1 CKAP2L CENPO RAD51AP1 XRCC1 KHK SPC24 DSCC1 PKMYT1 BRIP1 CAD RAD18 BLM LRRC45 ZNF587 SKP2 PSRC1 CKLF INCENP KNSTRN CKS1B NCAPG2 CDKN2C NUSAP1 CBX5 ASF1B IQCB1 ZNF45 CDK1 HDGF RNPC3 POLE2 CEP97 EXOSC2 CENPJ RFWD3 CENPH BIRC5 C1orf112 GMNN POC5 POLR3K E2F1 UNG NCAPG DNA2 MRPL17 TCTN2 KIF2A NEIL3 FEN1 EZH2 NUP205 SPAG5 TNPO2 SAPCD2 OARD1 SF3B3 TTI1 NAPEPLD MTBP ATAD3A DIAPH3 RECQL4 CENPP RNASEH2A KPNB1 RANGAP1 CHCHD3 NRGN NET1 SNRNP25 MYO19 DNMT1 FANCG INTS7 CCNE1 CEP192 TUBG1 DCLRE1C DLGAP5 ARHGAP11B FOXRED1 TACC3 SNRPA MNS1 RAD9A LONP1 KIF22 TRIM37 SSRP1 FBXO4 TK1 DTYMK CHTF18 CENPQ ESCO2 GINS2 FZR1 ANP32E PKP4 AGPAT5 TCEA1 KIF20B SAP30 ANAPC1 BCL2L12 POLD1 NUP85 MAGOHB ATAD5 CDC7 NIF3L1 DHTKD1 CENPK SASS6 SUPT16H FN3KRP PFAS CKAP5 L3MBTL2 KLHL23 BRD8 CDC20 PALB2 CENPM AAAS EFHC1 C12orf65 FAF1 RRP9 GPATCH4 POP7 CDR2 FANCM CDK5RAP2 MCM6 METTL2B CKAP2 XRCC4 MCM5 ANKRA2 HEATR1 TDP1 ZRANB3 SNRPD1 HAUS6 FAM161A TFAP4 SRSF1 GINS3 DOLPP1 EXOSC5 RCC1 HAUS4 SLC1A5 LSM4 MARCKS WDYHV1 ATAD2 CEP152 TCERG1 NUP62 CEP85 SUV39H2 ALMS1 MSH2 CCNA2 PRIM1 DZIP3 PRR11 DCPS GTF3C2 SHCBP1 RFC5 GTPBP2 USP39 WDR4 ABHD10	up	***
REACTOME_DNA_STRAND_ELONGATION	0.0000014	0.0000374	0.6435518	0.6794206	2.262688	30	CDC45 PRIM2 GINS1 MCM4 MCM2 MCM8 GINS4 POLA2 POLD2 MCM7 MCM3 LIG1 DNA2 FEN1 GINS2 POLD1 RPA1 MCM6 MCM5 GINS3 PRIM1 RFC5	up	***
BLUM_RESPONSE_TO_SALIRASIB_DN	0.0000000	0.0000000	1.0574636	0.4705938	2.262545	307	CPS1 SIM2 TRIP13 KIF20A CDC45 TROAP BUB1B NUP107 NEK2 CENPF TIMELESS PBK NDC80 BRCA1 IRS1 TTK SLC27A2 POLE STIL PLK1 AURKB CENPA PTTG1 AKR1C1 ESPL1 CDC6 SOX9 TPX2 CCNB2 MCM2 TYMS CDC25A MYBL2 COCH PRC1 ORC1 CCNF ZWINT ZNF107 LSM5 SCG5 RANBP1 HMMR EXO1 KIF23 CHAF1A MKI67 HLTF KIF15 PAFAH1B3 BUB1 FANCA TOP2A AURKA CBX3 POLA2 KIF2C RRM2 PRKDC PKM KIF11 GPSM2 MCM3 CHAF1B CDC25C MCCC2 SOX4 LIG1 ZNF443 RIPK4 SLC9A3R1 TOPBP1 CHEK1 ORC6 MAD2L1 SOX11 RAD51AP1 FNTB RGS4 SLC25A10 SKP2 PARP1 INCENP CDKN2C NUSAP1 PLOD2 CDK1 POLE2 GMNN E2F1 NCAPG NARF FEN1 EZH2 SPAG5 CBX1 RECQL4 RNASEH2A KPNB1 PIAS3 DNMT1 COL1A1 TUBG1 TACC3 TUBB2A KIF22 TK1 DTYMK HDAC1 GINS2 KIF20B POLD1 ENC1 CDC7 CDC20 ACLY RPA1 SRRT UPK1B MCM6 MCM5 SNRPD1 DDX23 SRSF1 SKAP1 MSH2 CCNA2 PRIM1 GTF3C2 RFC5 NME4 RAD51 CARHSP1 SRP9 PGAM1 VDAC3 TNS3 SMC2 NPTX1 MTHFD1 CDC25B UBE2C	up	***
BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN	0.0000058	0.0001345	0.6105269	-0.5741752	-2.261564	38	RBP4 TEK PECAM1 FABP4 EMCN CAV1 TGFBR2 TXNIP ERG SFRP1 TUBB6 CCDC82 VWF FOXN3 PDK4 ADCY2 MFAP4 CD34 NECAB1 MRGPRF SPARCL1	down	***
REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX	0.0000006	0.0000174	0.6594444	0.6766982	2.257182	31	CDC45 MCM10 PRIM2 POLE CDC6 MCM4 MCM2 ORC1 MCM8 CDT1 POLA2 MCM7 MCM3 ORC6 POLE2 GMNN CDC7 RPA1 MCM6 MCM5 PRIM1	up	***
FISCHER_G2_M_CELL_CYCLE	0.0000000	0.0000000	0.9101197	0.4864088	2.232724	210	HMGA2 TRIP13 FOXM1 KIF20A HJURP TROAP CHEK2 BUB1B NEK2 CCNB1 CENPF PLEKHA5 POLQ PBK KIF18B TTF2 NDC80 DEPDC1 PIF1 DEPDC1B SIX4 TTK CDCA2 RACGAP1 IQGAP3 GTSE1 DBF4B KIF14 ANLN ASPM STIL CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 TPX2 CCNB2 PRC1 CCNF MELK HMMR KIF23 CEP55 MKI67 KIF15 BUB1 TOP2A CENPL AURKA VANGL1 KIF2C MPHOSPH9 KIF11 GPSM2 CDC25C MAD2L1 CKAP2L ZNF587 PSRC1 KNSTRN CKS1B CDKN2C NUSAP1 CDK1 TNFRSF21 BIRC5 NEIL3 SPAG5 TNPO2 SAPCD2 NET1 DCLRE1C ARHGAP11B TACC3 KIF22 FZR1 ANP32E KIF20B SPA17 SAP30 NIF3L1 CKAP5 BRD8 CDC20	up	***
REN_BOUND_BY_E2F	0.0000003	0.0000082	0.6749629	0.6023038	2.232361	52	NDC80 PRIM2 TTK CENPA PTTG1 CDC6 E2F3 CDC25A UMPS ORC1 HLTF TOP2A POLA2 E2F2 PRKDC RAD54L MCM3 CHEK1 MAD2L1 CBX5 CDK1 UNG FEN1 TK1 POLD1 MCM6 MCM5 MSH2 CCNA2 RAD51 SMC2 CENPE TP53	up	***
MORI_IMMATURE_B_LYMPHOCYTE_DN	0.0000000	0.0000014	0.7195128	0.5479749	2.228212	81	HJURP CDC45 MCM10 NEK2 CCNB1 NDC80 CDCA7 TTK IQGAP3 E2F8 CENPA CCNB2 MCM2 PRC1 DTL MELK MKI67 TOP2A CENPL MCM7 RRM2 CDCA5 RAD54L MCM3 LMNB1 LIG1 CHEK1 CKS1B CDKN2C NUSAP1 CDK1 UCK2 EZH2 CBX1 DNMT1 DLGAP5 ANP32E CKAP5 CDC20 MCM6 CCNA2 SMARCA4 PRIM1 RAD51	up	***
SONG_TARGETS_OF_IE86_CMV_PROTEIN	0.0000003	0.0000106	0.6749629	0.6030754	2.226708	51	FOXM1 FLAD1 PTTG1 TPX2 MCM2 TYMS UMPS MYBL2 ZWINT CDT1 MCM7 KIF11 MCM3 TOPBP1 DNAJC9 MAD2L1 BLM TMEM106C CDK1 E2F1 UNG EZH2 CCNE1 TK1 RPA1 MCM6 MCM5 DDX23	up	***
BURTON_ADIPOGENESIS_1	0.0000357	0.0006642	0.5573322	-0.6018770	-2.226466	28	WEE1 THBD LITAF FOXC2 RHOB ID3 PER1 MAFF SLC25A25 IL6 SGK1 TSC22D1 IRS2 ETS2 CEBPD NR4A2 DNAJB4 NFIL3 DUSP2	down	***
GAVIN_FOXP3_TARGETS_CLUSTER_P6	0.0000000	0.0000016	0.7195128	0.5483396	2.224540	80	KIF20A MCM10 FBXW8 BUB1B NEK2 CCNB1 CENPF IGF2BP3 PBK ASPM PLK1 NUF2 CDCA8 AURKB TPX2 CCNB2 FIGNL1 TYMS HMMR CEP55 BUB1 AURKA KIF2C CLSPN RRM2 MMS22L CDCA5 RAD54L SERPINA3 SPC24 CKS1B NCAPG2 NUSAP1 CDK1 BIRC5 NCAPG SPAG5 ABHD4	up	***
MORI_LARGE_PRE_BII_LYMPHOCYTE_UP	0.0000001	0.0000032	0.7049757	0.5524560	2.223056	78	HJURP CCNB1 NDC80 CDCA7 TTK RACGAP1 E2F8 CENPA CCNB2 MCM2 MYBL2 PRC1 DTL MELK SMARCC1 KIF23 MKI67 TOP2A CENPL AURKA MCM7 RRM2 CDCA5 MCM3 LMNB1 LIG1 CKS1B CDKN2C ASF1B ANAPC5 CDK1 CBX1 RANGAP1 KIF22 ANP32E CDC20 HMGA1 MCM6	up	***
RHODES_UNDIFFERENTIATED_CANCER	0.0000002	0.0000058	0.6901325	0.5814184	2.219161	60	TRIP13 FOXM1 CCNB1 KIF14 CENPA CDC6 MCM2 MYBL2 CCT6A NCAPD2 NME1 MELK NUDT1 KIF23 TOP2A KIF2C GPSM2 MCM3 MAD2L1 CXCL9 CKS1B CDK1 SSBP1 BIRC5 EZH2 ILF2 COL1A2 DLGAP5 PSMD2 CDC20 MCM6	up	***
JAEGER_METASTASIS_UP	0.0000027	0.0000667	0.6272567	0.6408249	2.216508	37	CENPF UCHL1 TUBB2B SPP1 GPI CDC6 NNT DTL GINS4 HLTF AURKA THBS4 KIF2C RRM2 PLOD2 MERTK NCAPG ADAM12 TACC3 IGHM	up	***
FLORIO_HUMAN_NEOCORTEX	0.0000020	0.0000521	0.6272567	0.8320482	2.215602	13	FUT6 FAM177B ZNF221 C20orf197 APOL1 MAP1LC3C SP140L LAMB4 POU5F1B	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_CYAN_UP	0.0001205	0.0019117	0.5384341	-0.6985218	-2.206656	16	USP12 CITED2 ADAM17 CSGALNACT2 CREBRF PSEN1 PTGER4 CDK17 PTP4A1 AKIRIN2 GNA13	down	**
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP	0.0000000	0.0000001	0.7749390	0.5065400	2.204138	128	KIF20A TFAP2A-AS1 HJURP CDC45 BUB1B CCNB1 CENPF TTK IQGAP3 GTSE1 GMPS ASPM PTTG1 CDC6 TPX2 CCNB2 UHRF1 MCM4 PRC1 SHMT2 XPOT PVT1 SPDL1 C19orf48 CHAF1A MKI67 BUB1 TOP2A AURKA SAE1 RRM2 LMNB1 SLC35G2 KIF3C BRIP1 AFAP1L2 NUSAP1 ASF1B BIRC5 NCAPG LARP1 SPAG5 RNASEH2A MZT2A MZT2B GRAMD1A DLGAP5 SNRPA MTA3 TK1 GEMIN5 ANAPC1 PWWP2A KPTN RAB15 URB1 TTLL6 ATAD2 AP2S1 PRR11 SCNM1 ANK2 WDR76 LINC00839 CENPE PAICS PCBD1 UBE2C NUP210 NCAPH MLLT11 ZNF37BP	up	***
EPPERT_HSC_R	0.0000001	0.0000024	0.7049757	-0.4584022	-2.203393	105	PAN3-AS1 FGD5 INSIG1 ST3GAL6 ABCB1 ERG ZBTB4 RBM7 MCTP1 EIF5 RNF125 DACH1 RGCC SPTBN1 ZEB1 ITSN2 TMEM38B FOXO1 KLF4 DRAM1 SOCS2 NPR3 HOPX ELK3 HES1 CRIM1 C2orf69 JUN EPC1 DDX5 KBTBD8 MSMO1 PLSCR4 TMEM107 MEIS1 RIMKLB TFPI TPT1 ZDHHC21 OSER1 DAPK1 MAFK DNAJB9 ZNF165 RPS20P22 FNBP1 DUSP6 PRKCH CD109	down	***
EGUCHI_CELL_CYCLE_RB1_TARGETS	0.0000068	0.0001513	0.6105269	0.7090968	2.201078	22	KIF20A NEK2 NDC80 CDCA8 ECT2 MCM4 MCM2 BUB1 MCM7 KIF11 MCM3 CDC25C FEN1 MCM6 MCM5 CCNA2 SMC2 CENPE	up	***
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_DN	0.0000000	0.0000003	0.7614608	0.5166674	2.198700	107	ATP10B CPS1 RHPN2 MYEOV ADH1C GMDS EPN3 HBA1 SULT1C2 PRSS2 ADRA2A PTPRN2 GCNT3 TFF3 BCL2L15 SDHAP3 AKR1C1 SLC4A4 HBB LIG3 VILL GSDMB CAPN13 HMMR CLDN15 KCNE3 VPS28 REEP6 ALDOB STEAP3 DDT SNRNP25 DPP3 C9orf152 ESCO2 FXYD3 ZBTB7B CENPV GOLM1 ENTPD3 LPCAT4 XRCC4 TMEM45B RER1 TMC5 BLVRB SYBU ETHE1 ALDH3A1 RBM19 PCBD1 CYSTM1 CAPN9 MUC1	up	***
MISSIAGLIA_REGULATED_BY_METHYLATION_DN	0.0000000	0.0000006	0.7477397	0.5168687	2.198113	108	FOXM1 CDC45 BUB1B NEK2 CENPF CYP2J2 KIF14 GMPS ESPL1 CDC6 TYMS PRC1 ZWINT CDT1 RANBP1 KIF23 MKI67 KNTC1 AURKA ITGB4 POLD2 MDFI PRKDC LMNB1 CDC25C LIG1 CHEK1 FBL CAD CDKN2C NUSAP1 CDK1 GMNN EZH2 SEMA3A RNASEH2A NRGN DNMT1 DLGAP5 HMGB1P10 SNRPA KIF22 TK1 DTYMK ENOSF1 CENPM MCM5 RCC1 CCNA2 PRIM1 RFC5 MICU1 SMC2 CENPE PAICS UBE2C NCAPD3 NCAPH KIAA0586 TMPO MECOM MSH6 SHMT1 DCLRE1A RAB26 HNRNPAB POLD3 SMC4 STMN1 HNRNPA1 PCDH7 TRIM28 RFC4	up	***
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP	0.0000000	0.0000000	0.8012156	0.4992869	2.197694	141	SLCO5A1 HJURP PARPBP CCNB1 CENPF POLQ UBE2T MND1 NDC80 BRCA1 ANLN ESPL1 RGS6 CDC6 TPX2 CCT6A NCAPD2 ZWINT LSM5 CLPTM1L MELK KIF23 CEP55 CHAF1A ZFYVE27 KIF15 KNTC1 TOP2A ODF2 KIF2C WDHD1 ZNF146 FANCD2 LMNB1 BRD9 CHEK1 DSCC1 BRIP1 BLM IKBKB NCAPG2 NUSAP1 POLE2 GMNN NCAPG FEN1 DLGAP5 CHTF18 ITFG2 DAP3 SAP30 ATAD5 CENPK EP400 FANCM THOC5 CKAP2 SNRPD1 MRPL51 ATAD2 RPS26 CCNA2 ZNF93 ANK2 ARHGAP11A SMC2 CENPE	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP	0.0000004	0.0000117	0.6749629	-0.4820324	-2.195727	77	CLDND1 ZBTB34 GPCPD1 ZCCHC2 CDC42EP2 RRAGC SPIRE1 KLF10 HIPK3 KLF6 SLC7A11 ZNF697 SPRY2 MYCT1 TIPARP DUSP3 CCDC82 RIT1 DUSP1 CREBRF SLC25A25 SGK1 JUN PTP4A1 GABARAPL1 ANKRD12 FBXO30 FAM126B RORA NRG1 SPOPL PIM3 EGR1 ZFP36 TNFSF18 CFLAR EMP1 PGF C15orf39 AGO2 DNAJB6 PRNP TNPO1 FGFR1OP2 NCOA3	down	***
SU_TESTIS	0.0000007	0.0000202	0.6594444	0.5915015	2.192324	52	BUB1B NEK2 COIL CCNB1 MPP6 TTK CCNB2 HMMR RPL39L BUB1 AURKA NUP155 SYCP2 KIF2C TEKT2 PHKG2 ABCB6 TOPBP1 GPR135 HSF2BP CDK1 EZH2 MTOR	up	***
UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN	0.0000388	0.0007125	0.5573322	-0.5681678	-2.191363	34	BMP2 SIK1 CITED2 NEDD9 HBEGF MAP3K8 HLX NR4A1 MCL1 KLF4 CXCL2 ATF3 DUSP1 PDK4 CREM RCAN1 KLF2 RGS2 GEM EGR1 NR4A2 ZFP36 NR4A3 PTGS2	down	***
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP	0.0000000	0.0000000	0.8266573	0.4895877	2.188210	165	FOXM1 HELLS KIF20A CDC45 BUB1B CCNB1 UBE2T GGCT NDC80 BRCA1 CDCA7 HILPDA ANLN ASPM STIL PLK1 YEATS4 CENPA ECT2 ESPL1 CDC6 UHRF1 MCM4 MCM2 TYMS PRC1 DTL ZWINT HMMR EXO1 KIF23 CEP55 MKI67 KNTC1 BUB1 TOP2A NUP155 MCM7 CENPW RRM2 CDCA5 KIF11 MCM3 ORC6 MAD2L1 DSCC1 PKMYT1 BLM IDH2 CKS1B ASF1B CDK1 UCK2 GMNN POLR3K E2F1 FBXO41 STEAP1 SAPCD2 RECQL4 TUBG1 TACC3 TUBA8 TUBBP5 FHL2 ENC1 CDC7 TNK1 MCM6 PLEK2 MCM5 ANKRD1	up	***
FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN	0.0000023	0.0000568	0.6272567	0.6065657	2.187128	45	FOXM1 CENPF TIMELESS POLE MCM2 TTLL4 NUDT1 CHAF1A AURKA POLA2 KIF2C MCM7 KIF11 MCM3 BLM CKS1B CDKN2C CDK1 E2F1 RNASEH2A TK1 CDC20 MCM6 MCM5 CCNA2 PRIM1 NFRKB CAP2 RFC5 MTHFD1 CDC25B UBE2C POLRMT RNF126	up	***
BROWN_MYELOID_CELL_DEVELOPMENT_UP	0.0000000	0.0000016	0.7195128	-0.4343301	-2.183871	127	SLC31A2 EREG CD52 ABHD5 OLR1 IL1B CD44 EMCN C5AR1 SLC15A3 BCL2A1 IL1RN FGR CD33 SGMS2 ANXA5 ANPEP HLX STOM SIRPA GRN MCL1 ATP6V1B2 MPEG1 PLAUR DAB2 MYO1B ITGAX ID2 CCND2 DSTN SLC6A6 DEGS1 HEXB HCK CD80 CTSS PGD TYROBP PLK3 JUNB CSTA PSTPIP2 CAP1 FPR2 CCR1 GSTM5 CEBPD SP100 SOAT1 PLGRKT HEBP1 IQGAP1 CNN2 EGR1 AOAH TREM2 ZYX FPR1 NFAM1 QSOX1	down	***
PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP	0.0000015	0.0000392	0.6435518	0.5827248	2.178164	54	FOXM1 TTF2 NDC80 AURKB CENPA MCM4 MCM2 MYBL2 NCAPD2 HMMR AURKA RAD54L TOPBP1 RAD51AP1 CAD BLM SKP2 CDKN2C CDK1 DNA2 EZH2 DNMT1 SNRPA CDC7 CDC20 RPA1 MCM6 MCM5 TCERG1 MSH2	up	***
TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN	0.0000997	0.0016261	0.5384341	-0.5647078	-2.176229	32	HHEX LYL1 TGFBR2 MS4A1 CD37 NFKB1 MAPRE2 RHOG IFNGR1 CD83 IRF8 REL MOB1A SERPINB1 GPR18 MMD CCND3	down	**
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN	0.0000000	0.0000001	0.7749390	0.4936178	2.174846	147	HMGA2 TRIP13 EYA1 FANCI BUB1B CENPF TIMELESS PRIM2 BRCA1 TTK KIF14 AURKB SIX1 PTTG1 ESPL1 TPX2 CCNB2 MCM2 LIG3 SRPK1 SHMT2 XPOT MYL6B NME1 MELK KIF23 CHAF1A MKI67 TOP2A AURKA KIF2C MPHOSPH9 KIF11 LMNB1 CDC25C SALL2 TOPBP1 DNAJC9 MAD2L1 PFKP BLM FADS2 MEOX1 DLG5 PARP1 CKS1B CBX5 CDK1 UCK2 CCT3 UNG FEN1 EZH2 NUP205 SPAG5 RNASEH2A ILF2 DLGAP5 SSRP1 ASNS CKAP5 CDC20 MCM6 DDX23 CACNB3 TCERG1 MSH2 PRIM1 MLXIP GTF3C2 RFC5	up	***
INAMURA_LUNG_CANCER_SCC_DN	0.0003304	0.0045715	0.4984931	-0.7356237	-2.174750	12	CAV1 MCL1 ADARB1 ADAMTS8 RASL12 VWF PHACTR2 ABCA8 ADAMTSL3	down	**
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP	0.0000000	0.0000000	1.0276699	-0.3796644	-2.173433	369	CXCL3 EREG ACP5 KMO SC5D CD52 IL1A FCN1 PHACTR1 PECAM1 OSBPL1A CD55 IL1B LTA4H FBP1 CYP27A1 SNX10 DCSTAMP LPXN RDX PID1 FYN LY86 LMO2 CCRL2 AQP9 MYD88 C5AR1 ALAS1 NEDD9 CD9 LAMP1 EPB41L3 TEX2 TMX4 DPEP2 PLA2G7 MCTP1 HBEGF SLC7A7 ASAH1 ENTPD1 GM2A TNIP3 ANXA5 KLF10 SLC7A11 STOM LAIR1 RGCC AKT3 CRTAM CES1 ZFYVE16 TCF7L2 TFRC ATP6V1H APOC1 FBXL5 IL10 CFD TLE4 KCNMA1 CASP1 KLF9 DAB2 DENND3 MYO15B ITPK1 CTSD CCL3 CDS2 CTBS SELL TM6SF1 DNTTIP2 PINK1 MATK ZNF706 HLA-DQA1 CRIM1 MAPRE2 NCOA1 HEXB SGK1 PDCD6IP CD48 C1QA MITF VAT1 SH3BP5 LTBP2 TREM1 TMEM251 ZNF804A PTGER2 ATP13A3 CXCL5 SLC3A2 RHOQ ICAM2 NKG7 RIN2 EMC7 TIMP2 CHPT1 TFEB TSC22D1 GALC CD81 APLP2 SOD2 LGALS3 CCR1 KYNU DECR1 ETS2 IL18 CCDC69 SLC31A1 CALHM2 MS4A4A ATP9B CDKN1C SIK3 NLRP3 TBC1D1 FDX1 BCAT1 DOCK4 MT2A GRPEL1 ARFGAP3 ACAT1 SPHK1 DMXL2 ATP6V0A1 TMEM184C EGR1 SERPINE1 BHLHE41 DUSP6 NR4A2 CX3CR1 CLEC4E LHFPL2 AOAH ITGAL	down	***
FURUKAWA_DUSP6_TARGETS_PCI35_DN	0.0000004	0.0000112	0.6749629	0.5554890	2.172972	68	HJURP CCNB1 CENPF POLQ PBK RACGAP1 STIL MMP1 AURKB CENPA TPX2 CCNB2 MCM4 PRC1 DTL NCAPD2 SIPA1L3 MAP7 CEP55 AURKA WDR3 KIF2C KIF11 ORC6 BLM KNSTRN NUSAP1 NCAPG DLGAP5 KIF20B CKAP2 MCM5 TCHP PRMT5 CCNA2 PRIM1 RTEL1 SHCBP1 ARHGAP11A	up	***
BASSO_CD40_SIGNALING_UP	0.0000004	0.0000124	0.6749629	-0.4627138	-2.172770	88	PHACTR1 IL1B PTPRE SIK1 CD44 BCL2A1 NCF2 SH2B3 MAP3K8 IFI30 LITAF SRGN ARHGEF2 CD58 STAT5A CCL22 CCL3 LAPTM5 CCL4 PLEK HLA-DQA1 SNN NCKAP1L RAC2 JUNB CCR7 CD83 GPR183 CD74 IRF5 EHD1 LRRC32 RXRA ICAM1 TNFAIP8 TRAF1 NFKBIA TNFSF9	down	***
WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP	0.0000000	0.0000000	0.9214260	0.4616511	2.168230	246	TSPAN8 UNC5CL STYK1 C1GALT1 GMDS ZMYND8 FRK TOX3 PLEKHH1 GALNT4 FA2H EIF2B5 BAIAP2L1 C4orf19 AGR2 AACS PLS1 ACY1 CIB1 SRPK1 TJP3 MANSC1 CLPTM1L BZW2 SYTL2 GFPT1 BPHL MYO10 SLC2A10 ICA1 TTC22 TTLL12 CD24 KDELR2 CC2D1A TMEM63A BACE2 EHF RABEP2 FUT2 FLNB MGLL UQCR11 DYRK2 ESRP1 ABHD17C ETFB NET1 GIPC1 ZGPAT ST14 GSS LLGL2 MRPL52 DOK4 C9orf152 HDAC1 HIP1R GALNT3 SLC22A23 GSTK1 SGSM3 FXYD3 TMEM30B JTB GALNT7 NADSYN1 DHTKD1 CENPV ACBD5 TSTA3 ERBB3 POP7 CHMP4C ABCC3 MRPL41 NOSIP LSM7 SLC35A3 OVOL2 MVP TC2N EPCAM DDAH1 MRPL14 C19orf33 SMARCA4 HDLBP TMC5 CANT1 DOHH MLLT6 ARRDC1 LRRC8B CHMP1A MROH1 TRAK1 AURKAIP1 UQCRQ EIF4G1 RAB25 GOLGA2 PPIA EPHB4 SART1 MUC1 RABL6 NQO1 CAMK2N1 PLAC8 MED16 RNF126 MFSD9 GSTP1 TMEM259 CRB3 PSMB10 TOMM40 MECOM MARVELD2 STARD10 MPST	up	***
BENPORATH_ES_1	0.0000000	0.0000000	0.9653278	0.4517615	2.167891	304	PTPRZ1 HELLS EGLN3 RUVBL1 PARPBP MCM10 GABRB3 SLC13A3 ELOVL6 CHEK2 BUB1B NUP107 PROM1 CCNB1 SOX2 IGF2BP3 PRIM2 TUBB2B DNMT3B AURKB PTTG1 ECT2 CDC6 RBBP8 MCM4 MCM2 LSR RAD54B CDC25A COCH GLDC ORC1 HPS3 MIS18A GINS4 CDT1 HMMR NUDT1 MAP7 CHAF1A IGF2BP2 BUB1 IDO1 PUS7 TMEM177 KIF2C MCM7 RRM2 TTLL12 CDCA5 WDHD1 PASK MCM3 PYCR2 AP1M2 SALL2 CD24 CHEK1 RAD51AP1 DSCC1 DBNDD1 PARP1 DCLK1 NCAPG2 CBX5 PAK1 DMKN CDK1 EPHA1 POLE2 CACHD1 DIDO1 BIRC5 ESRP1 GMNN NPM3 UNG DNA2 PDK1 FEN1 NLN MAD2L2 HAS3 ITPR3 MYO19 TRIM24 DLGAP5 PUS1 SNRPA MTA3 SALL4 L1TD1 GINS2 BCL2L12 EPB41L4B ETV4 PFAS CDC20 MAN2A1 HMGA1 KRT8 MCM6 MGME1 DNMT3A CYP2S1 MCM5 CAPRIN2 SRSF1 LRIG1 EXOSC5 GAD1 EPCAM KLHL7 MSH2 CCNA2 PRIM1 ZNF195	up	***
VERHAAK_AML_WITH_NPM1_MUTATED_UP	0.0000000	0.0000006	0.7477397	-0.4145768	-2.161904	150	CXCL3 EREG HMOX1 FCN1 IL1B FBP1 SNX10 CAT AQP9 C5AR1 SLC15A3 BCL2A1 EPB41L3 TRIB1 PILRA LILRB3 FGR CD36 DPEP2 MCTP1 LMNA IFI30 PBX3 PTX3 CASP1 PTAFR PLAUR CPVL THBS1 ABCC4 CTSD CCL3 CXCL2 CCL4 TLR4 CD300C PLEK HCK NINJ1 TRGC2 HCAR3 ADCY2 IL6 C1QA HK3 TREM1 LGALS2 ACSL1 PELI1 SORT1 CD86 SOD2 MEIS1 CCR1 LTBP1 ETS2 CCL20	down	***
HOLLERN_EMT_BREAST_TUMOR_DN	0.0000000	0.0000016	0.7195128	0.5080469	2.160596	108	RHPN2 LTF CEACAM1 KLC3 PLEKHH1 EFNA3 ILDR1 SPINT2 LSR GRB7 KRT15 EPS8L1 TJP3 CLDN1 MAP7 STAP2 CBLC TMEM184A RNF43 AP1M2 CD24 RIPK4 SPINT1 EHF DDR1 GRHL2 WWC1 NRTN EPHA1 ESRP1 SDR42E1 CDH3 TMEM79 MYO5B IRF6 ST14 ARHGEF16 LLGL2 PKP3 KIF21A HIP1R SPTBN2 ELMO3 EPB41L4B FXYD3 TMEM30B TNK1 ERBB3 C1orf56 CDCP1 EPCAM PRSS8 CDH1 GRHL1	up	***
ANDERSEN_CHOLANGIOCARCINOMA_CLASS2	0.0000000	0.0000002	0.7614608	0.4901382	2.159515	147	DKK1 STYK1 GPR87 LEMD1 SCIN MYEOV C1GALT1 BIK PPP1R1B CDH17 GALNT6 GCNT3 PTPRR SIX4 PPP1R14D GPR35 TTK BCL2L15 ANLN FA2H TPX2 CCNB2 VSTM2L ANKRD22 HOXB7 FERMT1 ASPHD2 VILL KRT15 EPS8L1 TJP3 ITGA2 SLC6A20 CEP55 KCNN4 LAMC2 CBLC KIF15 BUB1 AUNIP TOP2A AURKA SLC4A11 KIF11 MYO1A GJB3 CDH3 SAPCD2 TSPAN1 ST14 COL1A2 DLGAP5 DTX2 CTSV PKP3 KRT19 FXYD3 COL11A1 CDC20 TFCP2L1 IGFL2 PLEK2 CYP2S1	up	***
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN	0.0000000	0.0000000	0.8390889	-0.4005147	-2.158949	198	FCN1 CXCL16 ADTRP MNDA GPR65 MIR22HG TUBB1 SAMHD1 CITED2 GPCPD1 C5AR1 CLEC10A STX11 MAL TGFBR3 NCF2 IL1RN IGSF6 CD8A FGR TXNIP CD36 CD5 CLEC7A IFI30 RGCC SLC25A37 MPEG1 KLF4 CPVL THBS1 PLBD1 CCL3 DOCK9 COTL1 CCL4 LBH PRF1 FCER1G IL7R PIK3R5 CA1 HCK CD8B RBP7 KLRB1 SGK1 IL2RB RGS18 ANKRD9 AQP3 SLC14A1 KCTD12 ETS1 TYROBP CSTA CCR7 SELENBP1 LGALS2 CST7 KLF2 NKG7 CD1D CD86 LGALS3 DOK2 GABARAPL1 CCR1 TOB1 GPR18 IL18RAP LAT RTN1 CEBPD EPHA4 MEGF9 KLRK1 RORA GIMAP4 MAN1C1 LYZ KLRF1	down	***
PUJANA_BRCA2_PCC_NETWORK	0.0000000	0.0000000	1.0476265	0.4414047	2.158408	387	DDX11 FOXM1 CDC45 FANCI ZNF273 TROAP CHEK2 BUB1B ZNF84 CCNB1 CENPF TIMELESS CPSF6 TTF2 CLGN NDC80 BRCA1 TTK GINS1 GTSE1 KIF14 GMPS POLE STIL AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 TFDP2 CCNB2 RBBP8 MCM4 PRKCA MCM2 TYMS MYBL2 CCNF LIG3 MAP2K6 SRPK1 NCAPD2 ZWINT CDT1 COX11 CASP2 MELK HMMR KIF23 CHAF1A MKI67 DCBLD2 HLTF PCCB KNTC1 BUB1 FANCA TOP2A AURKA CBX3 SYCP2 ATR POLD2 KIF2C MCM7 CD2AP MPHOSPH9 RRM2 PRKDC TRRAP WDHD1 RAD54L KIF11 MCM3 LMNB1 CDC25C LIG1 TOPBP1 CHEK1 DNAJC9 MAD2L1 NFYA RAD51AP1 MDM2 CAD BLM CNOT3 SKP2 CASP6 CDKN2C TMEM106C CDK1 POLE2 EXOSC2 FAT1 RBCK1 E2F1 UNG DNA2 FEN1 EZH2 NUP205 SPAG5 TTI1 CBX1 RNASEH2A DNMT1 ZNF354A FANCG TRIM24 CDC23 GNPAT DLGAP5 NINL SNRPA KIF22 SSRP1 DTYMK ANP32E KIF20B TMEM186 POLD1 CDC7 CKAP5 CPSF4 CDC20 RPA1 CLINT1 MCM6 TBCA MCM5 DPY19L2 DDX23 AATF LSM4 CHRNA5 TCERG1 PMS2P1 MSH2 CCNA2 SMARCA4 PRIM1 RFC5 WDR77 MRPL9 SRP9 PAXIP1 SNRNP200 ZNF131 SMC2 CENPE TCF3 PFDN4 SMPD4 SEPHS1 PAICS CDC25B UBE2C PNN TAF4 NELFA RAD1 DDB2 ZNF253 NUP93 TRAPPC6A NCAPH CYB5B CSTF1	up	***
LINDSTEDT_DENDRITIC_CELL_MATURATION_D	0.0000098	0.0002108	0.5933255	-0.5129957	-2.158207	55	ACP5 RBMS2 PTPRE EGR2 CLEC10A MKNK1 NCF2 IGSF6 ANXA1 NAAA ITGA5 MTMR6 CCL22 DAB2 TPP1 ITGAX PTGER3 ARHGDIB AQP3 RAB31 NPR1 ATP6V1A CCR1 FCGRT CLEC2B CCNH	down	***
ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN	0.0000334	0.0006316	0.5573322	-0.5398412	-2.157614	41	NCF2 ATP2B1 CAV2 GATA3 UBE2D3 PPP3CC SOCS2 CCL3 AXL CCL4 ARL4A JUN PTGER2 TNFRSF9 FOXO3 IRF5 GEM FGF2 RAPGEF3 CDC14A SERPINE1 CENPC CFLAR CYP1B1 ZFHX3 RGS20 RALGDS DUSP10	down	***
BURTON_ADIPOGENESIS_PEAK_AT_24HR	0.0000046	0.0001094	0.6105269	0.6174371	2.153888	38	KIF20A CCNB1 LCN2 RACGAP1 ANLN AURKB PTTG1 PRC1 MELK HMMR BUB1 TOP2A CENPL AGT CDC25C DCTPP1 CAD NUSAP1 CDK1 RANGAP1 KIF22 TK1 CDC20 SRSF1 EXOSC5 CCNA2 SNRNP70 UBE2C	up	***
TANG_SENESCENCE_TP53_TARGETS_DN	0.0000016	0.0000422	0.6435518	0.5816853	2.147730	51	KIF20A NEK2 PBK TTK RACGAP1 AURKB CENPA PTTG1 TPX2 CCNB2 CDC25A PRC1 KIF23 BUB1 TOP2A KIF11 LMNB1 NUSAP1 IGFBP5 CDK1 BIRC5 EZH2 SPAG5 NRGN TK1 KIF20B CDC20 IL12RB2 NUP62 CCNA2 CENPE UBE2C PDP1	up	***
BROCKE_APOPTOSIS_REVERSED_BY_IL6	0.0000000	0.0000014	0.7195128	-0.4197045	-2.141991	135	SIK1 CD44 ST3GAL6 GAS6 HEG1 IER2 HBEGF RAPGEF4 EIF5 MAP3K8 LITAF CAV2 EIF4E RB1 HNRNPU MCL1 EPB41L2 EVI2B DUSP3 ID3 STK17B ID2 PLEKHB2 EVI2A ADIPOR2 SH2D2A MAFF HCK CD8B PHTF2 SGK1 PNO1 SOCS3 JUN JUNB IFNGR1 HSPA13 GRB2 CDK17 PTP4A1 FOXO3 MSMO1 TGIF1 DPM1 DUSP5 ZBTB11 PIM1 GNA13 LTBP1 ICAM1 SF1 CXCR4 TMEM184B DAPK1 DNAJB9 LDLR RNF13 ARFGAP3 DNAJA2	down	***
LY_AGING_MIDDLE_DN	0.0000489	0.0008732	0.5573322	0.7586237	2.133413	15	FOXM1 CCNB1 CENPF PLK1 CENPA MYBL2 CCNF KIF23 KIF2C KIF11	up	***
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR	0.0000000	0.0000015	0.7195128	0.4967326	2.133208	120	EYA1 CHEK2 EYA2 TIMELESS POLQ BRCA1 POLE RBBP8 XRCC2 LIG3 EXO1 TP53BP1 POLM RHNO1 EME1 ATR POLD2 CLSPN PRKDC EME2 TOPBP1 CHEK1 RAD51AP1 XRCC1 BRIP1 BLM PPP5C PARP1 POLE2 DNA2 FEN1 DCLRE1C POLL RAD9A RAD51D POLD1 SLX4 RAD50 PALB2 RPA1 UBE2V2 KDM4B XRCC4 TDP1 UIMC1 CCNA2 RTEL1 RFC5 RAD51 EYA4 PAXIP1 SIRT6 TP53 RAD1 PIAS4 PARP2 MUS81 SPIDR TOP3A ATRIP RNF8 HERC2 RMI1 XRCC5 TIPIN PPP4C POLD3 XRCC6 RMI2 RAD51B RFC3 BARD1 POLE4 RFC4	up	***
PID_TGFBR_PATHWAY	0.0000095	0.0002053	0.5933255	-0.5117078	-2.128234	51	CAV1 NEDD4L TGFBR3 TGFBR2 RHOA PPP2R2A SPTBN1 ZFYVE16 DAB2 SMAD7 TGFB2 PPP2CA PPP1R15A SKIL GRB2 PPP2CB TGFB1 PARD6A ZFYVE9 SMAD2 FKBP1A ARRB2 DACT2 TAB2 ITCH SMAD4	down	***
TAVOR_CEBPA_TARGETS_UP	0.0000350	0.0006567	0.5573322	-0.5091390	-2.126103	49	HMOX1 FIG4 BCL2A1 IL1RN TRIB1 ANXA1 BTG2 LITAF PTX3 KIAA0513 PTPRC KCNMB1 ID2 ARC CCND2 BTG1 SERTAD2 TRGC2 HCAR3 RAB31 GLIPR1 CD7 ACSL1 SOD2 RGS2 CXCR4	down	***
AMIT_SERUM_RESPONSE_60_MCF10A	0.0000296	0.0005687	0.5756103	-0.5086660	-2.125903	52	EREG TRIB1 IER2 BMP1 HBEGF MAP3K8 RHOB CYBRD1 KLF7 PNRC1 INHBA SGK1 RCAN1 PTGER4 MBNL2 COBLL1 TGIF1 C1orf116 DUSP5 IRS2 ETS2 CCL20 PDLIM5 PMAIP1 EGR1 PXMP4 NR4A2	down	***
AMIT_SERUM_RESPONSE_40_MCF10A	0.0001564	0.0023993	0.5188481	-0.5651266	-2.121711	30	WEE1 CXCL3 IL1A SLC16A4 CITED2 GM2A KLF6 NR4A1 MCL1 CLIC4 CXCL2 ATF3 DUSP1 JUN FOS FOSB RGS2 GLUL EGR1 NR4A2 FPR1 ZFP36	down	**
REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING	0.0000846	0.0014108	0.5384341	-0.5292113	-2.120018	40	FYN CBL CRK STAT5A HCK IL2RB JAK1 RAPGEF1 PIK3R1 GRB2 PRKACA YWHAZ UBB TEC CSF2 CSF2RB IL5 PIK3R3 UBC JAK2 SYK UBA52 PIK3CA PTPN11 LYN	down	**
REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS	0.0000124	0.0002646	0.5933255	0.6170320	2.119432	36	CDC45 MCM10 CDC6 MCM4 MCM2 CDC25A ORC1 MCM8 ATR MCM7 CLSPN MCM3 CDC25C CHEK1 ORC6 RAD9A CDC7 RPA1 MCM6 MCM5	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN	0.0000050	0.0001161	0.6105269	0.5803425	2.113502	48	ELOVL6 BUB1B PAGR1 NDC80 E2F8 PLK1 ESPL1 CCNF MKI67 KIF15 AURKA ZNF174 TTLL12 PPP1R35 SPC24 PML SKP2 CDKN2C PPIL2 EXOSC2 NEIL3 TACC3 ENOSF1 PRMT7 CCDC51 NIF3L1 GEMIN6 CDC20 CCNA2 ZNF93 POLR3B DHRS3 RRS1 NR2F6 FAM111B TMPO XAF1	up	***
WONG_ENDMETRIUM_CANCER_UP	0.0000360	0.0006676	0.5573322	0.6906167	2.112628	21	KIF1A LTF SAA2 HP TFAP2A S100A2 TFF3 LCN2 FOXA1 SERPINA3	up	***
LY_AGING_OLD_DN	0.0000037	0.0000874	0.6272567	0.5716789	2.110784	51	FOXM1 CCNB1 CENPF CDK4 KIF14 PLK1 CENPA MCM2 TYMS MYBL2 CCNF RANBP1 KIF23 ATR KIF2C KIF11 FBL PKMYT1 PARP1 CKS1B	up	***
MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN	0.0000054	0.0001248	0.6105269	0.5794596	2.110286	48	TRIP13 KIF20A HJURP CDC45 CENPF CDCA7 CDCA2 CDCA8 CDC6 TPX2 DTL MELK CEP55 AURKA KIF2C MCM7 KIF11 CDKN2C CENPH MIR3939 MNS1 KIF20B CENPK	up	***
REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	0.0006525	0.0078825	0.4772708	-0.7130687	-2.108070	12	HES1 RBPJ MAML2 NOTCH1 RUNX3 KAT2B CREBBP SNW1 EP300	down	**
VANHARANTA_UTERINE_FIBROID_DN	0.0000172	0.0003539	0.5756103	-0.4862455	-2.107337	59	GATA2 PHYHIP SOX17 RTN3 CITED2 NR3C1 GIMAP6 TRIB1 IER2 KLF4 ATF3 PTGER3 SMAD7 WFS1 MAFF ACKR3 KLF2 HIVEP2 GSAP PDLIM1 LTBP1 GSTM5 TFPI MS4A4A PTCH1 DAPK1 ABCA8 CBX7 EGR1 NR4A2	down	***
REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TN_POLYAGGLUTINATION_SYNDROME_TNPS	0.0000148	0.0003091	0.5933255	0.8174172	2.105010	12	MUC5B MUC13 C1GALT1 MUC4 MUC16 MUC5AC MUC20 MUC6	up	***
GOLUB_ALL_VS_AML_DN	0.0004310	0.0057334	0.4984931	-0.6463173	-2.104305	18	CAT CD33 STOM SRGN MCL1 CST3 CFD CTSD ITGAX LGALS3 NFKBIA LYZ ZYX	down	**
JI_CARCINOGENESIS_BY_KRAS_AND_STK11_UP	0.0000066	0.0001480	0.6105269	0.8778302	2.103890	9	COL17A1 GPR87 TP63 KRT5 TFAP2A PKP1	up	***
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN	0.0000000	0.0000012	0.7337620	-0.4028752	-2.103571	152	EPAS1 CXCL3 SLPI STAC FCN1 HVCN1 GLIPR2 RAPGEF2 PID1 C5AR1 CDC42 MARCO NCF2 CD9 SLC11A1 PLA2G7 DNAJC3 SLC7A7 ENTPD1 CLEC7A RNASE1 DACH1 ANKRD29 IL10 SPNS3 KCNMA1 DAB2 PLBD1 ATP6V0D2 TM6SF1 IL7R HLA-DQA1 RPS6KA2 PDK4 SGK1 SLCO2B1 C1QA JUN ETS1 HK3 ELOVL7 CXCL5 CST7 KLF2 GJA4 SRSF6 CR1	down	***
REACTOME_DAP12_INTERACTIONS	0.0002235	0.0032465	0.5188481	-0.5448982	-2.102957	33	SIRPB1 FYN CD300E KLRD1 CD300LB TYROBP TREM1 PIK3R1 GRB2 SIGLEC15 PLCG2 KLRC2 SIGLEC14 VAV3 LAT KLRK1	down	**
REACTOME_DNA_REPLICATION	0.0000001	0.0000047	0.6901325	0.4908102	2.101194	117	CDC45 MCM10 PRIM2 GINS1 POLE CDC6 E2F3 MCM4 MCM2 ORC1 MCM8 GINS4 CDT1 POLA2 POLD2 MCM7 E2F2 MCM3 LIG1 ORC6 PSMD4 SKP2 ANAPC5 POLE2 GMNN E2F1 PSMB5 DNA2 ANAPC7 FEN1 PSMC4 CCNE1 CDC23 PSMA5 PSME2 GINS2 FZR1 ANAPC1 POLD1 PSMD2 CDC7 PSMB3 RPA1 MCM6 MCM5 GINS3 PSMB4 CCNA2 PRIM1 ANAPC2 RFC5	up	***
PUJANA_BRCA_CENTERED_NETWORK	0.0000001	0.0000043	0.6901325	0.4936911	2.100924	107	FANCI CHEK2 TIMELESS TTF2 NDC80 BRCA1 GINS1 POLE ESPL1 TFDP2 RBBP8 MCM4 MCM2 MYBL2 NCAPD2 HMMR CHAF1A TOP2A AURKA PRKDC RAD54L LMNB1 TOPBP1 MAD2L1 RAD51AP1 CAD BLM CNOT3 SKP2 CDK1 UNG DNA2 EZH2 DNMT1 SNRPA CDC7 CPSF4 CDC20 RPA1 MCM6 TBCA MCM5 AATF TCERG1 MSH2 CCNA2 SMC2 TCF3 PAICS UBE2C RAD1	up	***
KAUFFMANN_DNA_REPAIR_GENES	0.0000000	0.0000000	0.8266573	0.4567527	2.097999	204	TP63 CHEK2 POLQ BRCA1 PMS2P5 POLE PTTG1 RBBP8 RAD54B PMS2 XRCC2 CIB1 LIG3 SMUG1 TOP3B RUVBL2 EXO1 NUDT1 CHAF1A TP53BP1 POLM FANCA TOP2A EME1 PMS2P4 POLA2 ATR POLD2 MAD1L1 RRM2 PRKDC RAD54L FANCD2 CHAF1B LIG1 TOPBP1 CHEK1 MAD2L1 RAD51AP1 XRCC1 BRIP1 RAD18 BLM ERCC2 MNAT1 RECQL5 PARP1 POLN POLE2 UNG NEIL3 FEN1 MAD2L2 RECQL4 TEP1 FANCG DCLRE1C FANCF MTOR POLL MBD4 RAD9A RAD51D SSRP1 MGMT POLD1 POLB RAD50 SUPT16H RPA1 FANCM UBE2V2 WRNIP1 XRCC4 TDP1 GADD45G PMS2P1 MSH4 PMS1 MSH2 RFC5 RAD51 SMC2 PNKP XPC MPG TP53 NEIL1 APEX1 RAD1 DDB2 ERCC3 ALKBH2 PARP2 MUS81 MLH3 TOP3A	up	***
WHITFIELD_CELL_CYCLE_S	0.0000000	0.0000018	0.7195128	0.4821687	2.096861	131	ANKRD18A ANKRD36C ABCC2 HELLS CDC45 UBE2T PRIM2 BRCA1 E2F8 CCDC14 AC011043.1 COL7A1 RBBP8 TYMS TMCC1 MCM8 ZWINT TRIM45 HAUS5 CASP2 CCDC150 EXO1 FANCA TOP2A ABCC5 RRM2 CDCA5 RHOBTB3 RAD54L RAD51AP1 DSCC1 CAPS PKMYT1 BRIP1 RAD18 BLM COQ9 ASF1B GOLGA8A DNA2 FEN1 EZH2 INTS7 MBD4 CENPQ ESCO2 CDC7 GOLGA6L4 KLHL23 CENPM EFHC1	up	***
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP	0.0000000	0.0000000	0.9969862	0.4285932	2.095466	391	ALDH3B2 PRR15 PPM1H PRLR SLC16A14 ENTPD2 EPHB3 BIK LAD1 ZG16B EPN3 GALNT6 PAGR1 IQCE GGCT TOX3 PLEKHA6 TTC39A SPDEF TFF3 CREB3L4 PRR15L HILPDA FA2H ABCA12 BCAS1 FLAD1 EFNA4 TRIB3 ANKRD22 C4orf19 AGR2 SPINT2 LSR CA12 GRB7 MARVELD3 PIP4K2C EPS8L1 C6orf132 TJP3 RSPH1 TMEM41A ZNF74 MAP7 FOXA1 PAQR4 CBLC MSX2 TMEM184A SYNE4 P4HTM SYCP2 SLC29A2 SFI1 ICA1 HOOK1 BLOC1S1 MCCC2 AP1M2 CD24 SIDT1 SLC9A3R1 PROM2 SPINT1 ZKSCAN1 EHF DDR1 RABEP2 GRHL2 SYMPK NOL3 IDH2 DHRS13 TMED3 TTC9 CAPN8 MB KIAA0556 EPHA1 ESRP1 PLCH1 TNK2 AAGAB SUN1 ABCC11 CDH3 TMEM79 RAB11FIP4 RALGPS1 KIAA1211L MYO5B FAM102A TSPAN1 ACVR1B IRF6 ULK1 ST14 FANCF DHRS4-AS1 LLGL2 PKP3 COG7 ROGDI C9orf152 MGMT TP53TG1 HIP1R HID1 KRT19 ELMO3 FXYD3 ESR1 TMEM30B JTB ZBTB7B RMND5B UBQLN4 USP18 ERBB3 PPP1R3D CHMP4C MYO5C MRPL41 ANXA9 SSH3 CACNB3 SCYL3 PRODH TBC1D30 RAB3D OVOL2 SUOX PRKD2 ANK3 TMEM45B TC2N PATZ1 EPCAM DOK7 PRSS8 ATP6AP1 CDH1 GRHL1 BLVRB HOOK2 ARRDC1 TNKS1BP1 SLC25A29 CHMP2A ERBB2 ENPP5 ADCY6 CAMSAP3 RHPN1 CGN RAB25 KIAA1522 DCAF11 MUC1 PLXNB1 AZGP1 ARHGAP8 PPP1R16A TRAPPC6A CYHR1 CAMK2N1 CXorf40A NR2F6 C11orf80 ARHGEF5 RAB40C SIGIRR RUSC1 TMEM229B TRPS1 TRPM4 PGAP3 MARVELD2 STARD10 OVOL1 CCDC6	up	***
KANG_FLUOROURACIL_RESISTANCE_DN	0.0000481	0.0008630	0.5573322	0.7342826	2.094008	16	SLC2A1 DDIT4 LAMC2 ITGB4 NFYA MST1R BACE2 FLNB	up	***
REACTOME_HOMOLOGY_DIRECTED_REPAIR	0.0000009	0.0000249	0.6594444	0.5037167	2.091012	94	TIMELESS POLQ BRCA1 POLE RBBP8 XRCC2 LIG3 EXO1 TP53BP1 RHNO1 EME1 ATR POLD2 CLSPN EME2 TOPBP1 CHEK1 RAD51AP1 XRCC1 BRIP1 BLM PARP1 POLE2 DNA2 FEN1 RAD9A RAD51D POLD1 SLX4 RAD50 PALB2 RPA1 UBE2V2 UIMC1 CCNA2 RTEL1 RFC5 RAD51 SIRT6 RAD1 PIAS4 PARP2 MUS81 SPIDR TOP3A ATRIP RNF8 HERC2 RMI1 TIPIN PPP4C POLD3 RMI2 RAD51B RFC3 BARD1 POLE4 RFC4	up	***
MITSIADES_RESPONSE_TO_APLIDIN_DN	0.0000000	0.0000000	0.8140358	0.4493937	2.089764	225	TRIP13 FOXM1 HELLS HJURP FANCI DEPTOR BUB1B NEK2 CCNB1 CENPF DROSHA KIF18B GINS1 RACGAP1 KIF14 GMPS ASPM CDCA8 CENPA PTTG1 ECT2 GPI TPX2 MCM4 PRKCA MCM2 TYMS MYBL2 FERMT1 NCAPD2 ZFP64 AVL9 ZWINT CDT1 MELK CHAF1A MKI67 BUB1 TOP2A AURKA CBX3 TPR RSRC1 RRM2 PRKDC TRRAP TOPBP1 AHCY CAD BLM SKP2 PARP1 CASP6 NCAPG2 NUSAP1 TMEM106C CBX5 URI1 HDGF BIRC5 AP3D1 NCAPG NUP205 FANCG CCNE1 EDEM3 DLGAP5 TACC3 SNRPA SLC37A4 AGPAT5 PSMD2 CDC7 SUPT16H PALB2 KIAA0100 ACLY CKAP2 MCM5 HEATR1 ADD3 DDAH1 MSH2 CCNA2 NBPF14 CDC42BPA SHCBP1 TPGS2 AGBL5 WDR76 PGAM1 SMC2 EIF4G1	up	***
MORI_LARGE_PRE_BII_LYMPHOCYTE_DN	0.0000397	0.0007258	0.5573322	-0.4980859	-2.089448	50	GPR65 LY86 SAMHD1 CD22 GGA2 MS4A1 LCP1 MCL1 PTPRC HLA-DQA1 BTG1 CTSS CD83 IRF8 PXK CD74 SERPINB1 MACF1 IGKV1D-39 PIP4K2A ALDH2 SOAT1 CTSH CNR2	down	***
BASAKI_YBX1_TARGETS_UP	0.0000000	0.0000000	0.8753251	0.4425689	2.087320	256	DKK1 TRIP13 DDX11 KIF20A HJURP MCM10 FANCI S100A2 BUB1B NEK2 CCNB1 PBK NDC80 DEPDC1 DEPDC1B GINS1 GTSE1 FOXE1 ANLN ASPM NDUFS6 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 CCNB2 UHRF1 MCM4 MCM2 TYMS PRC1 DTL MIS18A NCAPD2 ZWINT SPDL1 MELK KIF23 CEP55 CHAF1A LAMC2 MKI67 BUB1 AURKA POLA2 SAE1 KIF2C MCM7 CENPW PRKDC WDHD1 MCM3 CHEK1 DNAJC9 ORC6 MAD2L1 CENPO SPC24 CAD COMMD4 FLNB WWC1 KNSTRN ASF1B OSMR CDK1 TNFRSF21 BIRC5 CCM2 UNG FEN1 DIAPH3 RANGAP1 MYO19 ILF2 SMG5 LMNB2 TUBB2A KIF22 TK1 DTYMK GINS2 PSMD2 DCUN1D5 CDC20 CENPM MCM5 ZNF599 SLC1A5 CCNA2 SHCBP1 RFC5 WDR4 WDR77 RAD51 ZWILCH ZNF71 RBM19 SMC2 RHOD SMPD4 MTHFD1 FRMD6 CBWD1 PRPF3 FGFBP1 UBE2C KRT80 E2F7 DDB2 RRS1 ZNF367 NUP93	up	***
PID_FOXM1_PATHWAY	0.0000193	0.0003924	0.5756103	0.5981196	2.086500	38	ONECUT1 FOXM1 CHEK2 NEK2 CCNB1 CENPF CDK4 PLK1 AURKB CENPA CCNB2 XRCC1 SKP2 CKS1B CDK1 BIRC5 CCNE1	up	***
KEGG_HEMATOPOIETIC_CELL_LINEAGE	0.0000225	0.0004466	0.5756103	-0.4609205	-2.086367	70	IL1A CD55 IL1B CD44 CD1C CD9 CD22 CD8A CD36 CD5 CD33 ITGA5 ANPEP MS4A1 TFRC CD37 EPOR IL7R CD8B IL6 CD7 CD34 CR1 MME CD1D CD19 KIT CD1E CD3G CSF2 HLA-DRB1 IL5 CD3E CSF3 ITGA6 CD4 GP5	down	***
ROSS_AML_WITH_CBFB_MYH11_FUSION	0.0000858	0.0014262	0.5384341	-0.5048307	-2.085789	46	CD52 CLEC10A MEF2A CD1C PTPRM SLC7A7 CLEC7A PLBD1 MYH11 CTSS KCTD12 MN1 LGALS2 TNFSF13 KIF17 CEBPD MEGF9 CD1E ANXA11 GIMAP4 DUSP6 S100A8 TES	down	**
KIM_WT1_TARGETS_UP	0.0000000	0.0000001	0.7749390	-0.3857255	-2.084834	202	SLPI EREG CSDC2 SOWAHC TBX3 PTPRE RCOR1 CD44 BAIAP2 FOSL1 BMPR2 NR3C1 RGPD5 OTUD4 TRIB1 IER2 ARHGAP29 ATP2B1 SH2B3 HBEGF LITAF KLF10 GLS PTX3 NR4A1 TNS1 SPRY2 ZEB1 ZNF365 PDGFA ZMIZ1 EVI2B MAP2K3 SRSF5 PLAUR KLF9 THBS1 NFKB1 ARC LBH INHBA MAFF SRF TRGC2 AREG SGK1 HPGDS SH3BP5 ETS1 JUNB FERMT2 GLIPR1 CD83 SPATA2L ATP13A3 GFPT2 CDK17 MBP SRSF6 FLNC DUSP5 NAB1 UTP3 PHLPP2 GEM ARAP2 PDLIM5 SF1 TIAM1 ACTB EPHA2 NFKBIA TIMP3 B3GNT2 GRB10 DNAJB5 SPHK1 EGR1 SERPINE1 HMGCS1 MYH10 ZYX ATP1B1	down	***
SHEPARD_BMYB_MORPHOLINO_DN	0.0000000	0.0000003	0.7614608	0.4690399	2.083195	159	SCIN FOXM1 FGA HELLS PARPBP GPT2 CCNB1 TOX3 TTK GINS1 CDCA2 IQGAP3 GTSE1 KIF14 ANLN ASPM AURKB CDC6 TPX2 GOLGB1 UHRF1 MCM4 MCM2 PRC1 CLDN1 MELK STRA6 KIF23 MKI67 ITGB4 SLC29A2 FGG KIF11 MCM3 TGM1 MDK LIG1 ACSF2 SOX11 RGS4 MGAT4B FAHD2A CDK1 BIRC5 GMNN PSAT1 DAP DNMT1 COL1A1 COL1A2 DLGAP5 TACC3 PRB1 TK1 GINS2 SLC4A2 CDC20 CENPM HMGA1 LIPG CKAP2 MCM5 NSD1 PFKFB4 RTKN MSH2 SLC2A5 PRIM1 PRR11 MIEN1 BLVRB BMS1 PAXIP1 WDR76	up	***
REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	0.0010643	0.0119679	0.4550599	-0.7300635	-2.083138	11	FFAR4 SPCS3 TCF7L2	down	*
REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1	0.0010643	0.0119679	0.4550599	-0.7300635	-2.083138	11	FFAR4 SPCS3 TCF7L2	down	*
REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	0.0005302	0.0068071	0.4772708	-0.6589052	-2.081506	16	LIMS2 LIMS1 PARVB VASP FERMT2 FLNC ACTB PARVA RSU1 ITGB1	down	**
GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN	0.0003892	0.0052920	0.4984931	-0.5918345	-2.078481	24	CD44 CAV1 NR3C1 TGFBR2 ANXA5 CASP1 PLAUR GAA CTSD TGFB2	down	**
MORI_PLASMA_CELL_DN	0.0001181	0.0018837	0.5384341	-0.5361338	-2.076325	35	LMO2 CD22 MS4A1 LAPTM5 COTL1 ELK3 CALM2 LRCH1 CD83 REL PANK2 PIK3AP1 BMP2K SPIB TSPY26P MICAL1 GPR137B TNFRSF13C GPATCH2L	down	**
CUI_TCF21_TARGETS_2_UP	0.0000000	0.0000000	0.9545416	0.4256532	2.076121	371	HMGA2 GRIP1 MEX3A HELLS EYA1 HJURP KCNK5 CDC45 TIMELESS UBE2T HOXB6 WFDC2 MPP6 TBRG4 PHGDH CDCA7 METTL1 IQGAP3 NIPSNAP1 LYPD6B ASPM NUF2 CDCA8 CENPA PTTG1 ALDH18A1 ESPL1 SLC4A3 TPX2 CCNB2 UHRF1 LSR TYMS DTL CLCN2 CDT1 NME1 RANBP1 BZW2 HMMR KNTC1 PAFAH1B3 POLD2 VASH2 TMEM132A MCM7 CDCA5 SBK1 MCM3 PLTP CHAF1B LMNB1 CDC25C EMG1 SALL2 MDK RBP1 BRI3BP SPINT1 DNAJC9 SOX11 MSI1 DCTPP1 XRCC1 PIH1D1 SPC24 DSCC1 CAD RAD18 BLM CLDN9 HSPBP1 SKP2 BMP5 INCENP THOP1 KNSTRN DCLK1 CKS1B CBX5 KRT18 CDK1 ARHGAP39 SERTAD4 PLCH1 C1orf112 ATIC ANKRD54 TCTN2 PSAT1 COL3A1 CCDC88C ATAD3A LRRC56 VPS72 TMEM231 CPXM1 SRD5A1 PA2G4 ZNF692 EVC2 NPHP1 COL1A1 RGS17 DCAKD TACC3 RBFOX3 FNDC4 MNS1 KIF22 MORN2 TK1 DTYMK NFATC4 COLEC11 PCDH9 PRMT7 POLD1 ESR1 CNDP2 CENPK PTN CENPV TIMM13 CKAP5 WDR34 KRT8 COMP CELF4 MCM5 NOC4L VCAM1 EXOSC5 LSM4 NT5DC2 PATZ1 PYCR1 CFH MMP16 CCNA2 RCN3 PRIM1 BANF1 DNAH1 RAD51 NLGN2 FMOD MRPL9 SNRNP70 MXD3 CLEC11A CAMSAP3 APEX1 SYNE2 MRPS27 UBE2C FAXC FAM185A NDUFB7 PPP1R14B TRAPPC6A RANGRF NCAPH CD38 PRKAR1B AKR7A2 ISLR UNC119	up	***
BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP	0.0000100	0.0002153	0.5933255	0.5751129	2.075661	46	BUB1B NEK2 IGF2BP3 CENPA ECT2 MCM2 TYMS COCH MKI67 HLTF PKM MCM3 ARPC1A NARF FEN1 TUBG1 DLGAP5 SLC26A2 TWF1 KIAA0100 MCM6	up	***
REACTOME_UNWINDING_OF_DNA	0.0000283	0.0005486	0.5756103	0.8056981	2.074831	12	CDC45 GINS1 MCM4 MCM2 MCM8 GINS4 MCM7 MCM3 GINS2 MCM6 MCM5 GINS3	up	***
SHEPARD_BMYB_TARGETS	0.0000062	0.0001395	0.6105269	0.5503164	2.070265	57	FOXM1 PARPBP CCNB1 TOX3 TTK CDCA2 GTSE1 KIF14 ANLN ASPM AURKB TPX2 GOLGB1 PRC1 MELK KIF23 MKI67 KIF11 MDK SOX11 CDK1 BIRC5 DLGAP5 TACC3 TK1 CDC20 HMGA1 CKAP2 RTKN PRR11 BMS1	up	***
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	0.0000000	0.0000000	0.8634154	0.4345429	2.069605	286	DDX11 KCNK5 TMEM86B NPIPB3 MSTO1 GPC2 EIF3B XPO5 INTS1 SPPL2B CUL9 QTRT1 CUL7 POLM FANCA SEMA6C TRRAP SETDB1 SLC4A11 PHKG2 CDC42EP1 TMEM63A HSF4 FBXL19 SNAPC4 SYMPK LTB4R CNOT3 ERCC2 C7orf26 PABPN1 MCTP2 PICK1 TNK2 ANKRD54 SUN1 ZMIZ2 NPM3 KCTD13 SMG9 CMTR1 AP5Z1 DHX33 LARP1 DPH7 TNPO2 RNF207 ATAD3A UQCC2 STK11 ZNF692 RANGAP1 GIGYF1 CDK3 DCLRE1C SMG5 TRMU MTOR PUS1 ZNF133 HIRA IQCG COPS7B HIP1R ACAD10 SGSM3 FBXO44 RBM33 ZBTB7B LSM14B ABCC10 EPN1 L3MBTL2 CLASRP ZNF202 SRRT ABCA7 MYPOP USP21 HHLA3 LRCH4 PIP5K1A NEURL4 RTKN RCC1 SH3BP5L TCHP U2AF2 NUP62 ZNF580 SPON2 CAPN15 ENGASE SMARCA4 ABCF3 MRPS25 CSNK1G2 R3HDM4 PPP6R2 ZMYND19 SNRNP70 LLGL1 UBAP2L MAPK8IP3 TCF3 ZNF793 SRCAP SBNO2 LEMD2 RANBP3 TMEM201 SCAF1 MAP2K2 SETD5 FBXL18 ANKRD13D ACIN1 GRIP2 DAZAP1 PDXP SETD1A ZNF316 SEC31B TEAD3 SPHK2 CRYGS FURIN REXO1 ZNF598 TMEM259 HDAC10 DEPDC5 APBA3 TNPO3 TRABD GGA1 URB2 ZNF638 SAFB2 ARMC6 CACTIN CNTROB ZNF524 TTC13 KMT2D EVI5L NUP214 SUGP2 SLC12A9 ZNF473 PPM1G GRAMD4 NSUN5P1 KHSRP PHF21A SLC39A3 CIC TTC17 ATF5 SH3BP1 LIMK2 DAGLB AMPD2 GBA2 ATXN2L FBXO46 SMARCD1 DRG2 TARDBP LPAR2 HDAC7 TECPR1 MBD3 ACAP1 ZNF444 AGRN AP5S1 KDM4A MIIP DMWD SEC61A2 ZNF646 SMG7	up	***
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP	0.0000001	0.0000031	0.7049757	-0.4037934	-2.068370	137	EPAS1 SC5D HMOX1 FBP1 CYP27A1 TIE1 THBD INSIG1 ENG AQP9 C5AR1 MARCO NCF2 CD9 ABCB1 HBEGF GM2A ABCG1 ANPEP TNS1 CD93 CD58 BST1 THBS1 MAFG TMBIM1 CDKN1A P2RY2 HPSE SMAD7 DSE MAFF HCK CLN8 CREM IFNGR1 DAPK2 MCAM ACSL1 TIMP2 TGFB1 CD1D CCR1 CCL20 EPHA4 GLUL BCAT1 KIT P2RX1 NRG1 SPHK1 EGR1 DKK3 FPR1 QSOX1 WNT5A	down	***
RUIZ_TNC_TARGETS_DN	0.0000001	0.0000027	0.7049757	0.4753989	2.065599	130	DKK1 TRIP13 FOXM1 HJURP CDC45 MCM10 FANCI PBK GINS1 E2F8 AURKB DIO2 CDC6 STC2 MCM4 MCM2 RAD54B TYMS CDC25A ORC1 DTL ZWINT SPDL1 MELK EXO1 AUNIP KIF2C MCM7 RRM2 RAD54L MCM3 EGFR CD24 DNAJC9 MAD2L1 PFKP RAD51AP1 DCTPP1 DSCC1 BLM NCAPG2 ASF1B CDK1 RFWD3 BIRC5 GMNN POLR3K E2F1 FEN1	up	***
MCLACHLAN_DENTAL_CARIES_UP	0.0000000	0.0000000	0.8012156	-0.3782405	-2.065488	210	SLPI ACP5 FCN1 PECAM1 CD55 SFRP4 IL1B MNDA CD44 C5AR1 BCL2A1 NCF2 IL1RN TRIB1 PLA2G7 MAN2B1 CLEC7A IFI30 ANPEP RNASE1 SLC7A11 MS4A1 LCP1 CD93 SRGN MCL1 APOC1 CD37 EVI2B MSR1 CFD PLAUR CPVL LY96 FAM49B CCL3 LAPTM5 PTPRC CD53 FCER1G ALOX5AP PLEK EVI2A INHBA IL7R HLA-DQA1 MAFF ARHGDIB HCK HCAR3 IL6 CTSS SOCS3 AQP3 CD48 C1QA RAB31 RAC2 TYROBP TREM1 PTGER4 IRF8 CXCL5 IGKV3-20 ACSL1 CD74 CD1D COL15A1 SOD2 IGHV3-23 CCR1 KYNU RGS2 CLEC2B IGKV1D-39 ICAM1 TNFAIP8 CEBPD MS4A4A CXCR4 CTSC SAMSN1 MT2A LYZ REEP1 CYBA CSF2RB C1QB CTSH	down	***
PUJANA_XPRSS_INT_NETWORK	0.0000000	0.0000012	0.7195128	0.4665946	2.064895	150	FOXM1 FANCI CHEK2 TIMELESS TTF2 NDC80 BRCA1 GINS1 GTSE1 POLE AURKB CENPA ESPL1 TFDP2 RBBP8 MCM4 MCM2 MYBL2 CCNF NCAPD2 ZWINT CASP2 HMMR CHAF1A MKI67 KNTC1 TOP2A AURKA CBX3 MPHOSPH9 PRKDC RAD54L LMNB1 TOPBP1 DNAJC9 MAD2L1 RAD51AP1 CAD BLM CNOT3 SKP2 CDKN2C CDK1 UNG DNA2 EZH2 DNMT1 SNRPA ANP32E KIF20B CDC7 CPSF4 CDC20 RPA1 MCM6 TBCA MCM5 AATF TCERG1 MSH2 CCNA2 PAXIP1 ZNF131 SMC2 TCF3 PAICS UBE2C PNN	up	***
PID_ALK1_PATHWAY	0.0005210	0.0067069	0.4772708	-0.5915765	-2.062054	23	ACVRL1 ENG CAV1 BMPR2 TGFBR2 SMAD7 INHBA TGFB1 FKBP1A ARRB2 SMAD4 MAPK1	down	**
KIM_WT1_TARGETS_8HR_UP	0.0000001	0.0000023	0.7049757	-0.3931036	-2.061822	157	EREG SWAP70 CSDC2 BAIAP2 FOSL1 QKI BMPR2 TBC1D2 BCL2A1 RGPD5 TRIB1 ATP2B1 HBEGF NLK KLF10 PPP3CA SIRPA ZMYM6 TNS1 BTG3 RAB14 ZMIZ1 MAP2K3 PLAUR PEG3 DAB2 ARC MAFF AFF1 SERTAD2 ID4 AREG RYBP SNAP23 JUN SH3BP5 HSPA1B JUNB PODXL GFPT2 RHOQ SRSF6 PEA15 TGFB1I1 PIM1 GEM RLF SRP72 HSP90AA1 TIMP3 DUSP7 FGFR1 NAA15 GRB10 DNAJB5 SPHK1 SERPINE1 HIPK1 FHOD1 ZYX DNAJB4 DNAJB1 PIAS2 WWTR1 CSPG4 TPST2 PLEKHO1 EMP1 CBFB IVNS1ABP ST3GAL1 ADAM19 SON	down	***
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	0.0000000	0.0000000	0.8870750	-0.3652471	-2.060886	312	HMOX1 OLR1 PDLIM2 PECAM1 CD55 MNDA LPXN GPR65 HSD17B6 FYN HSD17B11 LMO2 ST3GAL6 LDB2 QKI EML1 GIMAP6 TGFBR2 HEG1 ZEB2 ERG ANXA1 PTPRM SLC7A7 TACC1 ENTPD1 CLEC7A TMEM204 IFI30 GLS JAM3 RGCC CD93 AKT3 TFEC ZEB1 SRGN TUBB6 FLI1 EVI2B MSR1 TLE4 CASP1 PLAUR CPVL DAB2 GRK5 LY96 ABCC4 LAPTM5 PTPRC AXL RECK CCND2 TM6SF1 CD53 FCER1G ELK3 SMAD7 EVI2A INHBA DSE HLA-DQA1 FOXN3 EMP3 SGK1 CTSS C1QA HPGDS KCTD12 MAP4K4 TYROBP FERMT2 GLIPR1 ACKR3 IRF8 RASSF2 GFPT2 CELF2 PLCG2 LMCD1 PKD2 CD74 XYLT1 MME CPA3 TCF4 TGFB1I1 PLSCR4 COL15A1 CCR1 RGS2 CLEC2B GEM LDLRAD4 IL18 CPQ SPARCL1 MS4A4A MFAP5 IFFO1 S100A4 PARVA TIMP3 PTEN SAMSN1 ZFPM2 GIMAP4	down	***
REACTOME_SIGNALING_BY_BMP	0.0005338	0.0068163	0.4772708	-0.5912035	-2.060754	23	SMAD6 ACVRL1 GREM2 BMP2 BMPR2 ZFYVE16 UBE2D3 SMAD7	down	**
YU_MYC_TARGETS_UP	0.0000260	0.0005058	0.5756103	0.5860187	2.059655	40	KIF20A CCNB1 RACGAP1 E2F8 ANLN ASPM PLK1 ECT2 CCNB2 DTL MKI67 BUB1 TOP2A AURKA DCTPP1 CKS1B CDK1 BIRC5 GMNN	up	***
FOURNIER_ACINAR_DEVELOPMENT_LATE_2	0.0000000	0.0000000	0.8266573	0.4367703	2.059210	257	TRIP13 DDX11 FOXM1 HJURP CDC45 FANCI ELOVL6 NUP107 DROSHA TIMELESS POLQ PAGR1 NDC80 DEPDC1 TTK GINS1 RACGAP1 ASPM PLK1 CENPA PTTG1 CDC6 MCM4 MCM2 CDC25A FERMT1 PRC1 CCNF DTL SRPK1 ZWINT CCT2 RANBP1 MELK CHAF1A LAMC2 GFPT1 IGF2BP2 EEF1E1 AURKA SAE1 KIF2C MCM7 RRM2 TTLL12 PRKDC MRPL3 MCM3 KDELR2 TXNDC5 DNAJC9 CAD BLM FLNB SKP2 CKS1B NCAPG2 NUSAP1 ANAPC5 CDK1 UCK2 RFWD3 BIRC5 MRPL17 FEN1 NUP205 METTL3 SF3B3 TTI1 RNASEH2A TUBG1 GINS2 ANP32E NOC2L NUP85 CDC7 NIF3L1 ETV4 GEMIN6 SUPT16H CKAP5 POP7 MCM6 PLEK2 RAI14 CDCP1 RCC1 PHC2 STK39 NT5DC2 ALG8 PRMT5 PMS1 FAM3C SMARCA4	up	***
ANDERSEN_CHOLANGIOCARCINOMA_CLASS1	0.0000113	0.0002428	0.5933255	0.5573207	2.057769	51	PKHD1 HKDC1 MPP6 PSPH GAL3ST1 SPP1 SLC4A3 WNK2 SYT12 SMYD2 DCDC2 MCCC2 NME5 OXTR RGS4 CLDN9 DBNDD1 VN1R1 GMNN CTXN1 SCTR PGBD5 HNF1B ANKRD1 PTHLH PATZ1 LPGAT1 LOXL4	up	***
KEGG_DNA_REPLICATION	0.0000440	0.0008009	0.5573322	0.6098345	2.056246	33	PRIM2 POLE MCM4 MCM2 POLA2 POLD2 MCM7 MCM3 LIG1 SSBP1 POLE2 DNA2 FEN1 RNASEH2A POLD1 RPA1 MCM6 MCM5 PRIM1 RFC5	up	***
LIM_MAMMARY_STEM_CELL_DN	0.0000000	0.0000000	0.9214260	0.4209268	2.052473	370	RHPN2 LTF ALDH3B2 PPM1H CEACAM1 PRLR BIK PPP1R1B BDH1 GABRP NGEF TFAP2A DNAJC12 FRK WFDC2 RAB3IP SPDEF CREB3L4 SLC5A1 ILDR1 BAIAP2L1 ACOT8 SFXN1 LSR GRB7 ACY1 CIB1 TDRKH MARVELD3 VILL AP1G2 GOLPH3L TJP3 MANSC1 CLDN1 TMEM41A NUDT1 ANO9 FOXA1 STAP2 CBLC PAFAH1B3 IDO1 IFT43 ICA1 COASY TPCN1 TOM1L1 MCCC2 AP1M2 CD24 SIDT1 SLC9A3R1 PDZK1IP1 SPINT1 EHHADH TBC1D8 TST GLE1 MBOAT1 PIGO TMED3 CMAS MB PAK1 KRT18 SLC39A11 FAM221A ARPC1A ABHD17C NUDT2 REEP6 WDR31 SDCBP2 FADD RAB11FIP4 RALGPS1 MYO5B CXCL17 SUSD4 RNASEH2A PYROXD2 MPI GIPC1 TSPAN17 ST14 DCLRE1C ARHGEF16 ATP6V0E2 ADAT1 UROS HDHD3 PLEKHG3 MAPK13 RAD51D MTA3 OS9 HID1 ACAD10 GSTK1 KRT19 SGSM3 ELMO3 SIL1 ESR1 POLB GOLM1 ERBB3 TFCP2L1 KRT8 MYO5C SSH3 ANKRA2 SIRT5 C1orf56 C5orf22 SLC35A3 ADD3 SCYL3 CCNG1 CORO2A MVP ALG8 EPCAM RER1 CDH1 DTX3L GRHL1 PCBD2 STAT6 OSBPL10 ARRDC1 HLCS MRPL9 SNX8 PTPRF ERBB2 ATG2A ALKBH6 CAMSAP3 CGN RAB25 KIAA1522 TLR5 RORC NUP210 ZSCAN20 MUC1 TK2	up	***
BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP	0.0006110	0.0075301	0.4772708	-0.5465334	-2.051869	29	KL KCNAB1 UBL3 REV3L ITM2B RUNX1T1 PDE8A RECK HERC1 SEC63 LIMCH1 EID1 RAB2A ZBTB16 RB1CC1 SRSF11 CCPG1 SIRT1 EFEMP1 FAT4	down	**
SMID_BREAST_CANCER_LUMINAL_A_DN	0.0002401	0.0034613	0.5188481	0.7295735	2.051718	15	CDC45 NDC80 KRT16 CDCA8 TPX2 MYBL2 TTLL4 TOP2A CCNE1 ANP32E CDC20	up	**
LENAOUR_DENDRITIC_CELL_MATURATION_DN	0.0000006	0.0000174	0.6594444	-0.4241511	-2.051651	107	CXCL3 FCN1 OLR1 IL1B LTA4H FBP1 CD44 C5AR1 SLC11A1 TXNIP BTG2 ANPEP CES1 CD37 BST1 PTAFR PLAUR CXCL2 FCER1G ELK3 EVI2A ARHGDIB NINJ1 EMP3 PSEN1 IDS CXCL5 LGALS2 TSC22D1 NFYC SOD2 KYNU ADAM10 CLEC2B RTN1 S100A4 SREBF2 BCAT1 NFKBIA LYZ DUSP6 LHFPL2 ITGAL NCF1 S100A8	down	***
MITSIADES_RESPONSE_TO_APLIDIN_UP	0.0000000	0.0000000	0.9545416	-0.3525314	-2.050743	383	KMO SC5D RAPGEF2 MIR22HG CLDND1 BDNF THAP9-AS1 BACH1 FOSL1 VAMP2 IDI1 NUDT9 OTUD4 FRAT1 TRIB1 CASP9 CCNL1 AVPI1 KIAA0355 HBEGF EIF1 ABCG1 KLF6 STOM RBM4 NFE2L2 NDEL1 CLK1 BTG3 MCL1 DIABLO RHOB MAP2K3 MTMR6 FOXO1 SRSF5 PIP5K1B KLF4 ID3 STK17B MAP1LC3B DENND3 PDE8A GMPR CCL3 RBMS1 PDE3B ID2 DUSP11 ARC PNRC1 CLK4 UBE2B DUSP1 ALOX5AP ELK3 BRF2 SH2D2A HES1 MAFF NRBF2 RABGGTB RSRC2 CDKN2AIP HGSNAT RPS6KA2 MOB4 MYLIP AREG RYBP CREM CTSS OASL NXF1 NECAP1 JAK1 PPP1R15A SKIL IFRD1 GLIPR1 ACKR3 STX5 MORC3 TSPYL1 RGS13 DENND4A SNRK SLC3A2 KLF2 FOSB DDX18 SPOP ADPRM BCAS2 PEA15 JMJD6 DUSP5 IRS2 C16orf72 HBP1 TERF2IP GABARAPL1 STX12 KANSL2 N4BP2L2 RGS2 SERINC3 MR1 DBNDD2 ATAD2B GTF2B JUND GEM ICAM1 LDLRAD4 INTS6 NEK1 CXCR4 SIK3 TOB2 ARIH1 OSER1 FNBP4 NFKBIA PDE4A NFU1 MTUS1 ABCA8 TNFSF9 P2RX1 ZNF165 SAMSN1 RORA THEMIS2 LDLR C2orf42 SFPQ FNBP1 ATP6V0A1 HERPUD1 PHYH CDC14A BHLHE41 DUSP6 AKTIP CENPC	down	***
MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP	0.0000541	0.0009581	0.5573322	0.7957137	2.049119	12	ANLN ASPM CENPA CCNB2 PRC1 CEP55 RRM2 NUSAP1 BIRC5 DIAPH3	up	***
REACTOME_KINESINS	0.0000156	0.0003241	0.5756103	0.5548055	2.048483	51	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 KIF27 KIF23 KIF15 KIF3B KIF2C KIF11 KIF3C KIF5A KIF19 KIF2A TUBB2A TUBA3D KIF22 TUBA8 KIF21A KIF20B KLC2 KLC4 KIF21B	up	***
CHASSOT_SKIN_WOUND	0.0010040	0.0114289	0.4550599	-0.7789819	-2.048266	9	EGR2 JUN JUNB REL FOS KLF2 FOSB EGR1	down	*
REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	0.0000025	0.0000618	0.6272567	0.4960321	2.042957	89	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 COPB2 KIF27 KIF23 KIF15 COPG2 COPG1 KIF3B KIF2C KIF11 KDELR2 KIF3C TMED3 NSF KIF5A STX18 KIF19 KIF2A TUBB2A TUBA3D KIF22 ARF5 TUBA8 KIF21A KIF20B KLC2 KLC4 KDELR3 GBF1 KIF21B COPZ1 ARFGAP1 TUBA4B COPA TMED9 CENPE COPZ2 TUBA1C	up	***
WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP	0.0000004	0.0000116	0.6749629	0.4738882	2.042639	125	TSPAN8 UNC5CL GMDS ELOVL6 FRK TOX3 GALNT4 ECT2 SFXN1 PLS1 ASPHD2 BZW2 GOLPH3 MAP7 SYTL2 GFPT1 MYO10 CPD CD24 BRI3BP KDELR2 PERP RASSF6 SLC39A11 ESRP1 ABHD17C GNPNAT1 ETFB OCIAD2 PBLD NET1 EDEM3 LLGL2 DOK4 GALNT3 SGSM3 TMEM30B GALNT7 ARHGAP12 ACBD5 TSTA3 ERBB3 GPATCH4 CHMP4C ABCC3 SLC35A3 PDIA4 STK39 EPCAM DDAH1 MLLT6 LRRC8B NME7 EPHB4 MUC1 NQO1 PLAC8 PDZD8 ABHD2 MECOM KIAA1841 KCNK1 ABCD3 ELL3 TMEM181	up	***
SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN	0.0001390	0.0021555	0.5188481	0.6575035	2.040929	22	CCNB1 GTSE1 TPX2 CCNF KIF23 AURKA MCM7 CDC25C KIF22 DTYMK CDC20 MCM6 CCNA2 CDC25B UBE2C	up	**
IIZUKA_LIVER_CANCER_EARLY_RECURRENCE	0.0005972	0.0073928	0.4772708	-0.7447588	-2.038008	10	LAPTM5 VIM CCND2 SGK1 DDX17 REL	down	**
RHODES_CANCER_META_SIGNATURE	0.0000144	0.0003024	0.5933255	0.5416437	2.035005	55	PLK1 TPX2 COPB2 NME1 PAFAH1B3 TOP2A CCT5 CBX3 MRPL3 MCM3 SOX4 KDELR2 AHCY CDK1 SSBP1 NUP205 MRPS12 SNRPE PSMC4 ILF2 COL1A2 DVL3 PSME2 HDAC1 TSTA3 ACLY	up	***
VERHAAK_GLIOBLASTOMA_MESENCHYMAL	0.0000000	0.0000002	0.7749390	-0.3794269	-2.033864	201	RAB11FIP1 SWAP70 LRRFIP1 THBD ENG C5AR1 NCF2 SLC11A1 TGFBR2 LILRB3 ARHGAP29 ANXA1 SH2B3 CLCF1 MAN2B1 ITGA5 IFI30 LCP1 LAIR1 GRN CASP5 MSR1 CYBRD1 CASP1 PLAUR DAB2 DRAM1 THBS1 PLBD1 LY96 TMBIM1 LAPTM5 RBMS1 PTPRC TLR4 DSE VAMP5 HEXB PROCR EMP3 LTBP2 HK3 CTSZ RAC2 PLK3 RHOG CSTA PTGER4 ACSL1 RRAS RBKS EHD2 ALDH3B1 DOK3 TEC LGALS3 PHF11 KYNU LTBP1 CLEC2B PLA2G15 CPQ TNFAIP8 MS4A4A SP100 SCPEP1 S100A4 ICAM3 SIGLEC9 CTSC THEMIS2 IQGAP1 CNN2 SERPINE1 LHFPL2 FHOD1 TGOLN2 BDKRB2 FPR3 FXYD5 MFSD1 MAN1A1 TES WWTR1 PDPN PIGP	down	***
PID_EPO_PATHWAY	0.0004155	0.0055815	0.4984931	-0.5406988	-2.030000	30	CBL SH2B3 RAP1A STAT5A EPOR NFKB1 SOCS3 RAPGEF1 PIK3R1 GRB2 PLCG2 MAPK8 TEC IRS2	down	**
REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA	0.0000312	0.0005954	0.5573322	0.5474569	2.029079	52	HP IGLV3-27 IGKV1-17 HBA1 HBA2 IGKV3-15 IGKV3-11 IGKV1-16 IGKV4-1 HBB IGKV2D-28 APOL1 IGLV1-44 HPR IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGLV7-43 IGLV6-57 IGLV1-47 IGKV1D-12 IGHA1	up	***
THUM_SYSTOLIC_HEART_FAILURE_UP	0.0000000	0.0000000	0.9436322	-0.3532102	-2.026810	367	SC5D CD52 SFRP4 MNDA CAT RDX ENG HSD17B11 PLEKHF2 ST3GAL6 CALCRL CYB5R3 INPP5A SFR1 ARL8B P2RY13 LAMP1 SLC11A1 TGFBR2 SCARA3 RHOA ADAM17 ENTPD1 EIF1 PICALM RNF125 SPIRE1 RNASE1 LCP1 LAIR1 JAM3 ZEB1 SRGN FLI1 EVI2B MSR1 AGO4 MPEG1 CASP1 TSPAN12 ZFAND5 THBS1 ARNTL SOCS2 TPP1 CLIC4 LY96 LAPTM5 PTPRC CXCL2 SELP CCL4 TLR4 M6PR CD53 FCER1G ALOX5AP UTP23 RBMS3-AS3 BCLAF1 ARHGDIB ACTR2 CLIC5 TSPAN18 CREBRF SLC8A1 VAMP3 ID4 CTSS LINC00339 IL2RB SNAP23 OASL UTRN C1QA HPGDS GIMAP2 LTBP2 HRH1 RAC2 TYROBP APBB2 IRF8 MBNL2 MFAP4 GTDC1 YWHAZ RALB ZBED5 APOL4 MORF4L1 NECAB1 YTHDF3 CD74 GIMAP1 EPHA3 TMEM230 NAB1 PDCD1 PLSCR4 ANKRD12 CLEC2B MR1 TRAC WDR1 ZNF438 RAB5A CDC42EP3 MS4A4A CXCR4 EPHA4 ACTB KPNA4 RBMS3 RBM48 BCAT1 CTSC EDN1 B3GNT2 DAZAP2 LPAR6 CNOT8 MIER3 LYZ C1QB CRTAP TMEM43 DKK3 CX3CR1 FUS GAS5 ITGB1 HP1BP3 PLXDC2 PIK3CG DNAJB4 XPO7 FPR3 BSG C6orf62 HLA-DRB1 ANGPT2 MATR3 MAN1A1 FCGR3A PAXBP1 SKAP2	down	***
SA_MMP_CYTOKINE_CONNECTION	0.0026780	0.0249752	0.4317077	-0.6580994	-2.026163	14	ACE SPN IL1B CD44 TNFRSF8 SELL TGFB2 TGFB1	down	*
SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_UP	0.0006427	0.0077816	0.4772708	-0.7393754	-2.023276	10	PID1 EMCN ACER3 SFRP1	down	**
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2	0.0000000	0.0000000	0.8986712	0.4161671	2.022997	359	CCNO RIBC2 PCSK6 MDM1 NGEF RPGRIP1L NEK2 ARMC3 APOLD1 STOX1 TTC25 CCDC113 SRGAP3 FANK1 CCDC74A STIL SAYSD1 TTC26 CEP70 IFT27 SAMD15 SPATS2 RAB36 COCH TMCC1 DZANK1 LRRC27 DCTN2 SLC4A8 AK8 DNAI1 RSPH1 ARMC4 SDHA PAQR4 C9orf116 FOXJ1 TSGA10 CLHC1 P4HTM ODF2 IFT43 POC1A WDR78 DPCD SPEF2 TEKT2 EFCAB12 CCDC89 CCDC114 PASK C7orf57 WDR66 PFN2 C11orf16 NME5 NEK11 MDM2 DNAAF3 HES6 SPATA17 CAPS DNAH11 C4orf47 CCDC138 CCDC40 ZNF346 GPX8 CCDC78 DRC1 TMEM106C C2orf50 PPM1E LINGO1 DNAH6 EFCAB6 ARHGAP39 STON2 MDH1B FAM81B KLHDC9 PAXIP1-AS1 NEK5 RALGPS1 KIAA1211L AK7 DNAH5 TMEM231 CASC1 FGFR1OP IFT52 C3orf67 ZNF606 DENND6B KIAA1257 SPEF1 CAPS2 BBS5 NPHP1 TRIM24 TUBG1 DNAH7 EFCAB2 PSME2 COG7 IQCG FBXO15 MORN2 IQCK HECTD1 LRWD1 SPA17 IQCH CEP128 TYRO3 TMEM232 DNAJB13 KIAA1549 AGBL2 IQUB CCDC30 EFHC1 ODF2L EML6 ZNF432 RAB15 NEK4 ZNF599 EFHB LRRK1 TTLL6 RSPH4A LRRC46 UNC119B STRBP CEP85 TTC12 SERPINI2 GBP1 CLUAP1 UHRF1BP1 ENKUR FRMD8 AIFM2 WDR49 VDAC3 TTC30B ZMYND10 E2F7 RNF32 MOK MAP3K19 NPTX2 SPATA33 DNAL4 ARMC2 PAQR8 DNAAF1 MAK TEKT1 WRAP73 WDR63 PLK4 CYTH3 MST1 SRI ROPN1L RSAD2 DZIP1 KIAA1841 AK9 XAF1 SNTN TPPP3 C1orf194 NETO2 KIF6 TMEM67 CEP112 HERC2 RMI1 CMPK2 CCDC65 C5orf49 BBS12 CEP19 KIF3A PIFO SNHG10 DNAL1 PPP1R32 IK MUC12 CIAO1 STPG1 NPHP4 ZC2HC1C NOD2 MAP6 PPIL6 DNAH12 IFT81 IFT74 AIG1 ZBBX ACTR6 ZNF200 MKX WDR92	up	***
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP	0.0000000	0.0000002	0.7614608	0.4395224	2.019688	205	PTGES HELLS RUVBL1 KCNK5 CDC45 TICRR MCM10 PAX9 C1QTNF6 DEPTOR DNAJC12 FRK PLEKHH1 BRCA1 CDCA7 SDK2 ECE2 SLC27A2 CDC6 STC2 RBBP8 UHRF1 MCM4 MCM2 CA12 XRCC2 DTL MCM8 MOCOS NR2C2AP NOS1AP EXO1 CHAF1A TPBG WDR3 POLA2 MCM7 MMS22L WDHD1 AKAP1 MCM3 BRI3BP SLC9A3R1 CHEK1 DSCC1 BRIP1 FLNB MBOAT1 PLOD2 POLE2 RAPGEFL1 NAV2 E2F1 UNG FEN1 TMEM120B NOP2 FAM102A PDCD11 SLC26A2 MYBBP1A KIF21A SLC22A5 GINS2 IFNAR2 SEC14L2 OLFML3 MRPS23 NOL6 MCM6 MCM5 ANXA9 TFAP4 GINS3 LRIG1 EXOSC5 SLC1A5 CHRNA5 PRIM1 BLVRB SYBU WDR4 WDR76 CELSR2 POLR1B PAICS RRS1 ZNF367 KCNK6 TPM1 ATP6V1C2 LONRF2 SFXN2 PEX11A HR RBL1 ABHD2	up	***
REACTOME_REGULATION_OF_SIGNALING_BY_CBL	0.0010560	0.0119473	0.4550599	-0.5986213	-2.019360	20	FYN CBL CRK HCK RAPGEF1 PIK3R1 GRB2 UBB	down	*
LY_AGING_PREMATURE_DN	0.0003413	0.0047104	0.4984931	0.6218886	2.019298	26	FOXM1 CENPA MCM2 TYMS MYBL2 CCNF RANBP1 KIF2C FBL PKMYT1 PARP1 CKS1B CBX1 ENPP2	up	**
REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_OXIDATIVE_STRESS_METABOLIC_AND_NEURONAL_GENES	0.0010685	0.0119904	0.4550599	-0.5983579	-2.018472	20	ATXN3 CAT NR3C1 PLXNA4 FOXO1 FOXO3 SOD2 SMAD2 SIN3A SMAD4	down	*
BIOCARTA_GRANULOCYTES_PATHWAY	0.0015638	0.0162903	0.4550599	-0.6759331	-2.018420	13	IL1A PECAM1 SELL SELP ICAM2 ICAM1 SELPLG C5 ITGAL CSF3	down	*
SHEN_SMARCA2_TARGETS_UP	0.0000000	0.0000000	0.9214260	-0.3465402	-2.018124	391	OSBPL1A RDX MED4 KIAA1109 YPEL5 PRKAR1A FBXO3 TMX4 NUMB ARHGAP29 KIAA0355 UBL3 SERINC1 TOR1AIP1 RB1 TMEM41B ITSN2 RAB14 FBXL5 EFCAB14 HNRNPA3 PRKD3 ROCK1 SEC24B CEP57 ACTR3 CAPZA2 PPP2R5C CUL5 GNAQ PAFAH1B1 BCLAF1 LMBRD1 COPS4 HSDL2 RSRC2 NCOA1 RAB6A KANK1 MOB4 RBPJ PRKRA COPS2 RBM34 NEK7 CUL4A C11orf58 OSTM1 SHOC2 RABGAP1 VPS26A SNX2 FBXO11 STX7 SP3 SDHD IDS RBM22 TRAK2 UVRAG NOL7 RALB TUBGCP3 RNF146 MORF4L1 PSMD12 ATG3 ZFAND6 STXBP3 PHF3 BAZ2B CRYZL1 DPM1 FEM1B ZCCHC10 TMEM230 NAB1 NFYC ATXN1 HNRNPH3 EXOC1 STON1 NPTN MACF1 SERINC3 SMAD2 CHMP3 DCTN4 SEC63 MTO1 CALCOCO2 TAB2 POLR2M SRSF10 ISCU RBM48 STAM2 LIMCH1 COPS8 RNF38 NFU1 DAZAP2 TRAPPC11 RHOT1 CREG1 TLK1 WDFY3 EID1 SMAD4 RAB2A HAT1 YTHDC1 ABI1 SETX UBR2 CDKN1B AKTIP CENPC HIPK1 SSB TGOLN2 TRMT1L FBXW2 NDFIP1 PPWD1 UNC50 KIDINS220 CTR9 MATR3 ANKHD1 PCMT1 CUL2 SMARCA5 RAB1A ORC4 SRP14 BBIP1 UFSP2 CAPN7 PJA2 NFYB SKP1 SCAF8 VPS13C LARP7 MRPS14 DENND4C SENP6 SON PUM2 ZC3H7A SUCLA2 NSMCE4A ISCA1 AASDHPPT FEM1C LEPROT TANK SOS2 EED TMEM126B ANKRD17 RNF130 SEC62 PRPF38B AKAP11 APPBP2 TNPO1 SLC25A46 PCNP NUDT21 XPA PSMG2 CD59 RAB7A RIOK3 PPP1R2 SNX5 TMEM135 SMAP1 ARFIP1 OSBPL8 RWDD3 TMED10 ZC3H15 MRS2 SOCS6 DCP2 SMC5	down	***
DALESSIO_TSA_RESPONSE	0.0019016	0.0190057	0.4550599	-0.6524938	-2.017407	15	STXBP6 ANXA1 SNAI1 ATF3 ARC PPP1R15A FOS TEX14	down	*
BIOCARTA_INTEGRIN_PATHWAY	0.0007558	0.0089736	0.4772708	-0.5225963	-2.013943	32	FYN CAV1 RHOA RAP1A TNS1 ROCK1 JUN RAPGEF1 GRB2 MAPK8 ACTN2 MAPK1 ITGB1 ZYX	down	**
BURTON_ADIPOGENESIS_PEAK_AT_2HR	0.0001741	0.0026330	0.5188481	-0.4985517	-2.012961	42	BTG2 NR4A1 FOXC2 RHOB MAP2K3 KLF4 ID3 THBS1 CXCL2 DUSP1 IL6 JUNB RHOJ PPP1R15A ACKR3 FOS FOSB RGS2 ETS2 CEBPD SERPINE1 NR4A2 ZFP36 DNAJB4 DNAJB1 PTGS2 TNFRSF1B TNFAIP6 DNAJB6	down	**
RUTELLA_RESPONSE_TO_HGF_DN	0.0000000	0.0000005	0.7477397	-0.3696859	-2.011638	209	RAB11FIP1 EREG CD52 FCN1 PHACTR1 PECAM1 CD55 LTA4H DPYSL2 PID1 FYN LY86 LMO2 FCER1A MYD88 C5AR1 NEDD9 GAS6 TMX4 CCNL1 DPEP2 HBEGF SLC7A7 KLF10 RGCC TCF7L2 MCL1 CCNI FBXL5 CFD TLE4 CASP1 ZFAND5 STK17B DENND3 MYO15B ITPK1 CDKN1A SELL DNTTIP2 HLA-DQA1 MAPRE2 NCOA1 BTG1 CD48 SH3BP5 MAP4K4 TREM1 RABGAP1 CD83 PTGER2 PPM1F CELF2 PELI1 RUNX3 ICAM2 CHPT1 CD86 GALC APLP2 DECR1 RGS2 ETS2 RNF138 CCDC69 IER5 MS4A4A CXCR4 CDKN1C SIK3 NLRP3 ICAM3 NEK3 CYTH1 NRG1 SFPQ MIS18BP1 GRPEL1 CACNA2D3 FNBP1 HERPUD1 EGR1 DUSP6 FKBP1B NR4A2 CX3CR1 AOAH ITGAL FPR1 ZFP36	down	***
REACTOME_CELL_CYCLE_CHECKPOINTS	0.0000000	0.0000001	0.7881868	0.4318418	2.011131	232	CDC45 MCM10 CHEK2 BUB1B NUP107 CCNB1 CENPF NDC80 BRCA1 GTSE1 PLK1 NUF2 CDCA8 AURKB CENPA CDC6 CCNB2 RBBP8 MCM4 MCM2 CDC25A ORC1 DYNC1I1 MCM8 ZWINT SPDL1 EXO1 TP53BP1 KNTC1 RHNO1 BUB1 CENPL ATR KIF2C MCM7 MAD1L1 CLSPN MCM3 CDC25C TOPBP1 CHEK1 ORC6 MAD2L1 PSMD4 CENPO MDM2 SPC24 PKMYT1 BRIP1 BLM INCENP ANAPC5 CDK1 CENPH BIRC5 PSMB5 DNA2 KIF2A ANAPC7 DYNLL2 PSMC4 CENPP RANGAP1 CCNE1 CDC23 PSMA5 RAD9A PSME2 CENPQ ANAPC1 PSMD2 NUP85 CDC7 RAD50 CENPK CKAP5 PSMB3 CDC20 CENPM RPA1 UBE2V2 MCM6 DYNC1LI2 CENPT MCM5 UIMC1	up	***
DANG_MYC_TARGETS_DN	0.0005875	0.0073057	0.4772708	-0.5468214	-2.008749	27	ACP5 HMOX1 TMEM126A LAMP1 ID3 CEBPA DLEU2 TGFB1 CSDE1 SERPINE1 CDKN1B ITGB1	down	**
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP	0.0000002	0.0000075	0.6901325	-0.3872819	-2.007616	146	SLC31A2 DENND5A PTPRE SIK1 CD44 CTSW CITED2 AGTPBP1 TRIB1 CD8A HBEGF CD33 CSGALNACT2 KLF10 KLF6 RGCC SPRY2 TCF7L2 CFD ITM2B ZFAND5 STK17B MAP1LC3B RBMS1 PDE3B ID2 ZBTB43 PRF1 PER1 DUSP1 EVI2A ARL4A N4BP2L1 BTG1 MYLIP HCAR3 JUN PSMA1 GLIPR1 GPR183 IGKV3-20 FOS KLF2 AZI2 FOSB MARC2 IRS2 RGS2 HELZ SF1 CEBPD SIK3 NFKBIA WDFY3 DMXL2 NR4A2 TGOLN2 ANKS1A ZFP36 ATP1B1	down	***
REACTOME_FOXO_MEDIATED_TRANSCRIPTION	0.0000716	0.0012359	0.5384341	-0.4756119	-2.006852	54	ATXN3 CAT CAV1 CITED2 NR3C1 TXNIP PLXNA4 AKT3 TXN FOXO1 KLF4 CDKN1A PINK1 BTG1 YWHAZ FOXO3 NFYC SOD2 KAT2B SMAD2 RBL2 CREBBP SIN3A SMAD4 CDKN1B YWHAB EP300 SIRT1 NFYB	down	**
REACTOME_DNA_REPLICATION_PRE_INITIATION	0.0000072	0.0001597	0.6105269	0.4993123	2.006735	77	CDC45 MCM10 PRIM2 POLE CDC6 E2F3 MCM4 MCM2 ORC1 MCM8 CDT1 POLA2 MCM7 E2F2 MCM3 ORC6 PSMD4 POLE2 GMNN E2F1 PSMB5 PSMC4 PSMA5 PSME2 PSMD2 CDC7 PSMB3 RPA1 MCM6 MCM5 PSMB4 PRIM1	up	***
MARKEY_RB1_ACUTE_LOF_UP	0.0000000	0.0000004	0.7477397	0.4354766	2.001371	206	HMGA2 TRIP13 KIF20A HJURP CDC45 NEK2 CCNB1 UBE2T BRCA1 RACGAP1 IQGAP3 E2F8 ANLN PLK1 CENPA ECT2 CDC6 CCNB2 FIGNL1 MCM4 TYMS PRC1 CCNF DTL COX6B2 CDT1 SPDL1 RANBP1 DNPH1 KIF23 MKI67 BUB1 AURKA SAE1 KIF2C MCM7 RRM2 HELB KIF11 MCM3 CHAF1B CDC25C TOPBP1 DNAJC9 ORC6 MAD2L1 AHCY RAD51AP1 DCTPP1 MDM2 PERP PPP5C IDH2 PARP1 CKS1B NUSAP1 TMEM106C CBX5 ASF1B ANAPC5 CDK1 BIRC5 GMNN NAV2 E2F1 PRRX2 KIF2A ETFB DLGAP5 KIF22 TRIM37 TK1 DTYMK HIP1R CENPK SASS6 YLPM1 CKAP2 MCM5 LSM4 CCNA2 PRIM1 BANF1 PTPRVP RFC5 DOHH HAS1 RAD51 TPGS2 SCOC	up	***
REACTOME_CHROMOSOME_MAINTENANCE	0.0000220	0.0004384	0.5756103	0.5274178	2.000455	59	HJURP RUVBL1 PRIM2 PIF1 CENPA MIS18A RUVBL2 CENPL POLA2 POLD2 CENPW LIG1 CENPO DSCC1 BLM CENPH DNA2 FEN1 CENPP CHTF18 CENPQ POLD1 CENPK CENPM RPA1 CHTF8 CENPT PRIM1 RTEL1 RFC5	up	***
FOSTER_TOLERANT_MACROPHAGE_DN	0.0000000	0.0000000	0.9101197	-0.3479963	-1.999757	372	CXCL3 OLR1 TAL1 USP12 HHEX GLIPR2 IL1B MNDA SNX10 LRRFIP1 ENG OTUD1 PLEKHF2 SAMHD1 CAV1 KIAA1109 MYADM CITED2 PRPF38A CASP12 NR3C1 TET2 NFIX HBEGF LMNA PPP1R15B MAP3K8 LUZP1 RNF125 HDC FOXP1 PTX3 BFAR ZBTB8A AKT3 ZEB1 TUBB6 TIPARP ATP10A IL10 CSRNP1 STAT5A CCL22 PPM1K PLAUR SLC12A4 DRAM1 SOCS2 KLF7 RMDN3 SEC24B MGAT4A NFKB1 CDKN1A CXCL2 SELP HOPX CCND2 FRMD4A GCA ARL4A N4BP1 UBASH3B KPNA3 AFF1 TANC1 CMTM6 KREMEN1 SNN FMNL2 DCP1A IL6 SOCS3 SRSF3 ETV3 MTMR14 LRCH1 NOTCH1 ST6GALNAC4 HSPA1B JUNB RCAN1 CD83 PCGF5 GYPC MALT1 REL HOMER1 ZNRF3 OGFRL1 FOS HIVEP2 RIN2 TCF4 DUSP5 CTNNAL1 KHDRBS1 CD86 PIM1 GPR84 GNB4 TAGAP PDE4B MOB3B IL18 PDLIM5 SERTAD1 ADAMTS4 XKR8 SETDB2 CEBPD TIAM1 ATP9B TAB2 RIPK2 TBC1D1 ZDHHC21 TRAF1 RND1 KATNA1 FNBP4 MAFK CTSC EDN1 MTUS1 TLK2 TNFSF9 AIM2 SFPQ GSPT1 FEZ2 MIER3 DNAJA2 SPATA13 SPHK1 IRF2 JDP2 SPSB1 SERPINE1 TNFSF8 TMEM30A ATP11B ZNF800 ENDOD1 ZYX ZFP36 PLEKHA2	down	***
BIOCARTA_CTLA4_PATHWAY	0.0023286	0.0225150	0.4317077	-0.6134810	-1.998768	17	CD80 PIK3R1 GRB2 CD86 CD3G ICOS HLA-DRB1 CD3E ITK CD3D PIK3CA CTLA4 PTPN11 CD247	down	*
SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP	0.0000125	0.0002646	0.5933255	0.5149436	1.993783	65	RIBC2 SPICE1 SLFN13 ABCA17P EIF2B5 TFDP2 MCM2 HAUS5 C5orf34 NR2C2AP TMEM41A HLTF KIF15 CENPW SDHAP1 LIG1 TOPBP1 ASS1 ACTL6A EHHADH RAD18 CDKN2C EZH2 CXCL17 POLR2H WDR53 GK5 CDC7 CENPK MEI1 MCM6 RAP2B NEFH YBX2 CELSR3 NUP210 RNF32 C9orf40 CRYGS ALG6 FAM111B	up	***
SMID_BREAST_CANCER_BASAL_UP	0.0000000	0.0000000	0.9969862	0.4007077	1.991268	512	KIF1A IGHV4-61 DKK1 CEACAM1 TRIP13 PTPRZ1 CA9 BBOX1 FOXM1 HS3ST1 HELLS EPHB3 GALNT14 KRT5 LAD1 KCNK5 CDC45 MCM10 GMDS GABRP FAT2 S100A2 CP PROM1 NEK2 UGT8 CENPF UCHL1 IGF2BP3 MPP6 PBK KIF18B PKP1 DDIT4 MUC16 NDC80 PHGDH CHODL TUBB2B LCN2 TTK GTSE1 TSPYL5 SPP1 ASPM MMP1 KRT16 CDCA8 CENPA PTTG1 TBX19 CCL8 SOX9 TPX2 E2F3 CCNB2 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 FERMT1 COCH GLDC ORC1 DYNC1I1 PDE9A MOCOS CDT1 IGKV2D-28 KRT15 LDHB CXCL10 TTLL4 CLDN1 MELK IGLV3-10 EXO1 NUDT1 GPR37 CEP55 KCNN4 CHAF1A LAMC2 RPL39L MKI67 TRIM29 IGF2BP2 BUB1 FANCA IDO1 HOMER3 MYO10 VASH2 MCM7 MDFI TMEM45A RAD54L GPSM2 CHAF1B PFN2 RBP1 EGFR RIPK4 CDC42EP1 CHEK1 PDZK1IP1 SOX11 PFKP RAD51AP1 BACE2 PERP PML WNT5B SKP2 EDN2 NRTN CXCL11 NUSAP1 PLOD2 PPM1E CDK1 TNFRSF21 FAT1 UCK2 BIRC5 PLCH1 ITGB8 IGHG1 TNNI2 PRRX2 TRIM2 GJB3 PSAT1 PEG10 PDK1 CDH3 MRPS12 ARTN RAB6B RTP4 SRD5A1 HSPA4L LGR5 CRLF1 CCNE1 DLGAP5 SLC26A2 CHST3 CTSV FNDC4 TUBB2A IQCG SSRP1 DBN1 S100A9 ANP32E IFNAR2 STEAP1B MMP7 ASNS	up	***
AMIT_EGF_RESPONSE_60_HELA	0.0002388	0.0034557	0.5188481	-0.4929519	-1.990351	42	CITED2 KLF10 KLF6 TIPARP RHOB MOAP1 PER1 HES1 MBNL2 GPRC5A RUNX3 FOSB SOD2 LDLR NAA15 PMAIP1 SERPINE1 NR4A2 NKTR NR4A3	down	**
DIRMEIER_LMP1_RESPONSE_LATE_UP	0.0002537	0.0036379	0.4984931	-0.4765204	-1.989891	49	HMOX1 OTUD4 RFTN1 BZW1 LITAF SERPINB9 CD58 STAT5A CCL22 NFKB1 PLEK ETF1 RHOG RUNX3 IRF5 NBN SPIB TRAF1 FEZ1 PIEZO1	down	**
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	0.0000000	0.0000000	1.1330899	-0.3231814	-1.987244	744	RAB11FIP1 CXCL3 SLC31A2 EREG IL1A HMOX1 SWAP70 ABHD5 PPARG SECISBP2L CD55 ATXN3 THBD BMP2 SIK1 BACH1 ST3GAL6 RASAL2 CITED2 CIR1 YPEL5 ARL8B MEF2A CDC42 RGPD5 NCF2 WBP4 TRIB1 SYNC CCNL1 ZEB2 DNAJB14 TXNIP NUMB HSPE1 KIAA0355 ATP2B1 CLCF1 RRAGC UBL3 ADAM17 EIF1 MTF1 EIF5 SERINC1 CSGALNACT2 KLF10 HIPK3 KLF6 PTX3 SLC7A11 GPBP1L1 PPP2R2A FOXJ3 TRAF6 NFE2L2 NDEL1 LAMTOR3 SPRY2 CLK1 ARHGEF2 ITSN2 TCF7L2 ATP6V1B2 TIPARP KPNA5 RHOB GMEB1 ZMIZ1 PER3 AGO3 SORBS1 KLF4 COQ10B KLF9 ANKRD10 KLF11 TJP1 STK17B MAP1LC3B TMED5 STX3 MAFG ZNF24 SPAG9 SNIP1 SEC24B PER2 RIT1 CDKN1A NR1D2 CXCL2 ATF3 PNRC1 ZBTB43 CLK4 UBE2B PLEKHB2 CCSER2 PER1 DUSP1 WDR48 BRF2 INHBA CPT1A N4BP2L1 DSE SLC6A6 N4BP1 PAFAH1B1 TP53BP2 MAFF PLCD1 NRBF2 IL24 MARK3 IKZF5 RABGGTB RSRC2 CDKN2AIP PI4K2A VCPKMT NCOA1 SNN RAB6A TOPORS ZNF426 BTG1 UFM1 RBM39 DCP1A ELF1 AREG IL6 RYBP ZNF442 PKNOX1 NSMAF COPS2 PSEN1 SNAP23 RAB8B OASL NXF1 HECA FAM189A2 VAT1 NOTCH1 HMBOX1 GABPA HRH1 CELF1 PLK3 DNAJA1 RABGAP1 RCAN1 PPP1R15A SKIL HSPA13 MBNL2 STX5 MORC3 PDZD2 EGLN2 GPRC5A IP6K1 SLC3A2 FOS ADNP2 RHOQ CDK17 PTP4A1 AZI2 HIVEP2 MBP FOXO3 TTBK2 CHORDC1 STXBP3 PHF3 JMJD6 BAZ2B OSGIN1 TSC22D1 FEM1B DUSP5 GNAI1 KHDRBS1 IRS2 DYNC1LI1 MAP3K2 PIM1 HBP1 CCDC68 SOD2 LGALS3 GABARAPL1 TOB1 ANKRD12 GNA13 N4BP2L2 RGS2 PLEKHO2 CLCN6 CSNK2A2 TCF7L1 PLA2G15 ETS2 IST1 ARPP19 GTF2B JUND GEM FGF2 IL18 ABL2 RLF ZNF143 CGRRF1 TFPI DCTN4 RAB5A CEBPD CDKN1C HSP90AA1 VPS4B USPL1 RIPK2 SIK3 EIF4EBP3 TOB2 ARIH1 UBE2D1 MEGF9 BRWD1 CREBBP OSER1 RBM48 FNBP4 CUL3 NFKBIA JMJD1C RNF38 MTUS1 LYST DNAJB9 TNFSF9 ZNF165 FGFR1 ITCH NRG1 GRB10 SFPQ WDFY3 PUM1 ATF4 SMAD4 ARFGAP3 TRIM36 PMAIP1 ZBTB40 MED17 DCUN1D2 RABGEF1 CSF2 ABI1 UBAP1 HERPUD1 SPSB1 UBR2 CHIC2 SLC25A38 GJC1 ATF2 LHFPL2 ING1 FTL RB1CC1 SLC38A2 ZFP36 YRDC CCNT2 PTGS1 DNAJB4 HEY1 SRSF11 DNAJB1 CCDC93 WAC GPR137B WDR47 TRIM13 TSC22D2 SERP1 EP300 IRF1 ATP2B4 NFIL3 MEF2D CHKA TRIM25 SETD2	down	***
REACTOME_CELL_CYCLE	0.0000000	0.0000000	1.0073180	0.3981861	1.986385	547	FOXM1 CEP72 KIF20A HJURP RUVBL1 CDC45 MCM10 CHEK2 BUB1B NUP107 NEK2 CCNB1 CENPF MND1 NDC80 PRIM2 PIF1 BRCA1 TUBB2B GINS1 CDK4 GTSE1 POLE CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 E2F3 TFDP2 CCNB2 RBBP8 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 ORC1 DYNC1I1 MCM8 MIS18A GINS4 NCAPD2 ZWINT CDT1 DCTN2 SPDL1 HAUS5 CEP250 RUVBL2 HMMR BTRC EXO1 KIF23 STAG3 TP53BP1 KNTC1 RHNO1 BUB1 TOP2A CENPL AURKA NUP155 REC8 ODF2 POLA2 SYCP2 ATR POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 E2F2 CENPW CLSPN RRM2 LPIN3 CDCA5 MCM3 LMNB1 CDC25C LIG1 TOPBP1 CHEK1 ORC6 MAD2L1 PSMD4 CENPO MDM2 SPC24 AKT2 DSCC1 PKMYT1 BRIP1 BLM MNAT1 SKP2 INCENP CKS1B NCAPG2 CDKN2C ANAPC5 CDK1 POLE2 CENPJ DIDO1 CENPH BIRC5 GMNN SUN1 E2F1 NCAPG PSMB5 DNA2 KIF2A ANAPC7 FEN1 NUP205 DYNLL2 PSMC4 CENPP FGFR1OP KPNB1 RANGAP1 MZT2A MZT2B CEP63 CCNE1 CEP192 CDC23 TUBG1 PSMA5 NINL RAD9A TUBB2A PSME2 TUBA3D TK1 TUBA8 CHTF18 CENPQ HDAC1 ESCO2 GINS2 FZR1 LIN37 ANAPC1 POLD1 PSMD2 NUP85 PPME1 CDC7 RAD50 CENPK CKAP5 PSMB3 CDC20 CENPM TUBG2 AAAS RPA1 CHMP4C CDK5RAP2 UBE2V2 MCM6 CHTF8 DYNC1LI2 CENPT MCM5 UIMC1 HAUS6 GINS3 RCC1 HAUS4 PSMB4 CEP152 NUP62 MSH4 ALMS1 CCNA2 PRIM1 BANF1 RTEL1 ANAPC2 RFC5 TUBGCP4 CEP164 LPIN1 TUBA4B RAD51 ZWILCH SEC13 FBXW11 NME7 CHMP2A SMC2 MAU2 CENPE TP53 GOLGA2 LEMD2 SYNE2 CDC25B UBE2C NCAPD3 TUBA1C PPP2R5D NUP210 RAD1 PIAS4 CLASP1 NUP93 FBXL18 NCAPH CEP290 CHMP6 DYNC1H1 MLH3 TOP3A PLK4 AKAP9 PCNT DSN1 CDK11B RBL1 PPP2R5E FBXO5 PSMB10 LCMT1 TUBGCP2 PSME1 ATRIP NSL1 TMPO NHP2 NPM1 RNF8 RCC2	up	***
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	0.0001808	0.0027132	0.5188481	-0.4870573	-1.984738	44	ANGPT4 TEK FYN ELF2 ITGA5 CRK STAT5A FOXO1 NFKB1 CDKN1A ELF1 ETS1 PIK3R1 GRB2 MAPK8 DOK2 FGF2	down	**
WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN	0.0012286	0.0132880	0.4550599	-0.5841733	-1.984446	21	LY86 CALCRL ERG CD93 IL7R CD34 TSC22D1 MEIS1	down	*
COLDREN_GEFITINIB_RESISTANCE_DN	0.0000000	0.0000006	0.7477397	0.4332985	1.984005	199	GPR87 KLC3 HS3ST1 BIK WFDC3 LAD1 EPN3 CYP2J2 PRR15L ANKRD22 AGR2 LSR GRHL3 PLEKHA7 KCNMB4 MARVELD3 KRT15 EPS8L1 C6orf132 TJP3 LAMC2 STAP2 SMAGP SYNE4 TTC22 AP1M2 RIPK4 B3GNT3 SPINT1 MST1R CAPS EHF DDR1 GRHL2 MBOAT1 CLDN9 CAPN8 EPHA1 ADAP1 PEG10 CDH3 RAB11FIP4 SLC44A3 KIAA1211L CCDC57 TSPAN1 IRF6 KANSL1-AS1 ST14 ADAM28 S100A16 MAPK13 ZNF468 GALNT3 SMIM22 KRT19 ELMO3 FXYD3 PRRG2 TMEM30B LIMA1 ERBB3 ANXA9 SLC35A3 OVOL2 STK39 TMEM45B TC2N DOK7 PRSS8 FAM3C CDH1 TMC5 GRHL1 PRSS22 MROH1 LRG1 WLS ENPP5 ZNF91 RHOD CGN RAB25 KIAA1522 FGFBP1 ZNF681	up	***
NIKOLSKY_BREAST_CANCER_7Q21_Q22_AMPLICON	0.0000351	0.0006567	0.5573322	0.5271404	1.983078	57	TFPI2 ASB4 BET1 BAIAP2L1 DYNC1I1 CYP3A5 PPP1R9A PON3 TRRAP ZKSCAN1 PON1 PON2 ARPC1A ZSCAN25 SLC25A13 PEG10 ZNF789 ZKSCAN5 COL1A2 LMTK2 ASNS FAM200A CLDN12 CPSF4 ANKIB1 GTPBP10 PDAP1	up	***
SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP	0.0000239	0.0004705	0.5756103	0.4992277	1.979948	73	CCNO TFPI2 PTPRT HBA1 GALNT6 TOX3 CLGN SPDEF TFF3 BCAS1 AGR2 CA12 PAH SLC4A8 KAZALD1 C9orf116 CHAD TOM1L1 INPP4B DCLK1 MB TSPAN1 SYT1 SIL1 ESR1 GALNT7 ANXA9 CEACAM5 TTC12 TMEM101 CAPN9 MUC1 NELL2 NAT1 GSTT2 PGAP3	up	***
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP	0.0000000	0.0000011	0.7337620	-0.3684284	-1.977755	200	RAB11FIP1 CXCL3 IL1A CXCL16 OLR1 ZC3H12C IL1B BMP2 NEDD4L BCL2A1 IL1RN IL23A DNAJC3 B3GNT5 HBEGF BTG2 KLF6 GLS PTX3 PAG1 ZNF697 CLN5 SERPINB9 SLC7A2 MAP2K3 TLE4 BIRC2 PTAFR PLAUR DRAM1 NFKB1 CDKN1A CXCL2 ATF3 IRAK2 PNRC1 INHBA DSE CLIP4 N4BP1 IL7R MAFF LACC1 BTG1 NINJ1 HCAR3 SGK1 PSEN1 SOCS3 OASL RWDD1 RASSF10 ETS1 IFNGR1 RCAN1 ELOVL7 CD83 TNFRSF9 TNFRSF10B SNX9 PELI1 EHD1 GSAP SERPINB1 KYNU ANKRD12 CCL20 ICAM1 TNFAIP8 RIPK2 TRAF1 NFKBIA EDN1 CYTH1 ZNF165 TMCC3 DOCK4 LPAR6 TNFRSF10D HERPUD1 SPSB1	down	***
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP	0.0000354	0.0006609	0.5573322	-0.4357963	-1.975463	69	SLPI MNDA CD44 MYADM CITED2 HMGCR IL1RL1 IL1RN SLC11A1 IER2 EIF1 SRGN MSR1 PIP5K1B DAB2 CCL3 NFKB1 CDKN1A ATF3 KPNA3 DEGS1 HCK ETF1 IFRD1 CLN3 BCL6B TGFB1 ETS2 CEBPD NFKBIA TNFSF9	down	***
GROSS_HYPOXIA_VIA_ELK3_DN	0.0000022	0.0000561	0.6272567	-0.3873600	-1.974617	134	CXCL3 SLPI RAMP3 MNDA PRKG2 THBD CD44 TXNL1 NEDD4L NEDD9 TSHZ1 USP47 HBEGF ANPEP KLF6 SLC7A11 TRAF6 CD93 SPRY2 SRGN CSRNP1 KLF4 CXCL2 ATF3 EPS15 PLEK ADIPOR2 AFF1 ZNF330 RBPJ GZF1 IL6 ETS1 RCAN1 PPP1R15A PTGER4 SKIL IFRD1 FOS TGIF1 PDLIM5 CDC42EP3 ACAP2 RND1 NFKBIA JMJD1C EDN1 SAMSN1 ATF4 RABGEF1 PIM3 EGR1 CHIC2 S100A8 ZFP36 BCL10 SCAF11 AKAP12 NFIL3 MAP3K1 CSF3 ITGA6 PTGS2	down	***
AFFAR_YY1_TARGETS_DN	0.0000000	0.0000010	0.7337620	0.4296683	1.974406	205	TSPAN8 MMP13 FOXM1 HELLS KIF20A MYCBPAP ELOVL6 BUB1B CCNB1 CENPF TTK RACGAP1 NIPSNAP1 SPP1 ASPM PLK1 AURKB CENPA ALDH18A1 CDC6 SFXN1 CCNB2 TRIB3 UHRF1 MCM4 SLC4A4 PRC1 LIG3 CDT1 HMMR EXO1 KIF23 MKI67 BUB1 TOP2A AURKA THBS4 KIF2C MCM7 TMEM45A KIF11 MCM3 LMNB1 CDC25C LIG1 RIPK4 MAD2L1 STEAP4 RAD51AP1 RAD18 FADS2 IGFBP5 CENPH BIRC5 UNG NCAPG STEAP1 GJB3 FEN1 SPAG5 DIAPH3 LGR5 SLC35C2 TACC3 TUBB2A KIF22 MRPL52 TK1 CHTF18 ANP32E IGHM SPA17	up	***
REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	0.0000774	0.0013153	0.5384341	0.5325883	1.973970	52	MUC5B MUC13 C1GALT1 GALNT14 GALNT6 MUC4 GCNT3 MUC16 CHST4 MUC5AC GALNT4 GALNT10 MUC20 MUC6 GALNT9 B3GNTL1 B3GNT3	up	**
WINNEPENNINCKX_MELANOMA_METASTASIS_DN	0.0013712	0.0146713	0.4550599	-0.5110245	-1.972227	33	CLIC3 CLEC3B DPYSL2 CRY2 CLEC10A CD1C TXNIP RNF125 CST3 CEBPA ST6GALNAC6 LGALS2 TOM1L2	down	*
SMID_BREAST_CANCER_NORMAL_LIKE_UP	0.0000000	0.0000000	0.9101197	-0.3384562	-1.971793	414	MGAT3 ACVRL1 CD52 SOSTDC1 PECAM1 HHEX FABP4 CLEC3B TIE1 LYVE1 THBD LYL1 FYN LPL EMCN CTSW CCDC88A FCER1A KANK3 CAV1 CRY2 CLEC10A ELMO1 TGFBR3 GIMAP6 CD1C CD22 FAM49A LILRB3 ABCB1 CD8A PDE2A TXNIP RNF125 MALL MS4A1 DES IL18R1 SFRP1 SPRY2 CES1 ZEB1 SRGN CD37 CNN1 PPP3CC FLI1 ADARB1 EVI2B TLE4 SORBS1 CASP1 AOC3 ST3GAL2 CPVL RUNX1T1 SLC12A4 FMO2 ID3 CLDN5 LY96 ITIH5 LAMC3 COTL1 RBMS1 PTPRC CXCL2 SELL CD302 PRF1 MATN2 MATK VAMP5 IL7R MYH11 MAPRE2 FOXN3 NCKAP1L TRGC2 FAM107A ID4 TMOD1 IL6 KLRB1 CD48 KCTD12 RAC2 PTGER4 CCR7 GLIPR1 PIK3R1 IRF8 GMFG GPR183 NPR1 MFAP4 SNX1 CD7 LGALS2 PALMD CELF2 IGKV3-20 RRN3 SIGLEC1 GJA4 HIVEP2 MBP RUNX3 ICAM2 NKG7 CD74 BIN2 MME TCF4 CD1D CD6 VPREB3 DOK2 GPR18 CLEC2B CCR6 GEM TRAC LAT TNFAIP8 CCDC69 SPARCL1 TFPI LMOD1 SPIB CDKN1C EPHA4 GIMAP5 NLRP3 ACACB MT1M CD19 KIT CTSC CD1E DOCK10 CD3G KLRK1 ABCA8 GPR171 THEMIS2 NR3C2 GIMAP4	down	***
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN	0.0000830	0.0013934	0.5384341	-0.4438430	-1.971177	64	GPD1 RBP4 SEMA3G PPARG FABP4 CLEC3B LPL APOD CD36 FZD4 PTX3 SFRP1 CES1 CFD AOC3 CEBPA CLDN5 ITIH5 PTGER3 PDK4 SELENBP1 NPR1 PALMD FOSB GPX3 LMOD1 ACACB METTL7A MARC1 RAPGEF3 ABCA8 C1orf115	down	**
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN	0.0000043	0.0001024	0.6105269	0.4760089	1.971002	93	BIK ZG16B EPN3 DNAJC12 PLEKHA6 TTC39A SPDEF TFF3 CREB3L4 ZFP62 PRR15L LAMP5 AGR2 SPINT2 CA12 COX11 RSPH1 FOXA1 BPIFB1 IFI44L AP1M2 NME5 SLC9A3R1 GRHL2 MB KRT18 SERTAD4 ABCC11 REEP6 KLHDC9 HID1 KRT19 FXYD3 ESR1 MYO5C LRRC17 OVOL2 ZDHHC11 ZSCAN16 EPCAM CDH1	up	***
MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP	0.0000061	0.0001393	0.6105269	0.4685469	1.970962	100	MDM1 CPLX2 CEP89 ELOVL6 BUB1B IGF2BP3 KIF18B PRIM2 UHRF1 AGK RANBP1 CISD1 MCM7 MMS22L WDHD1 LIG1 TOPBP1 AHCY CENPO DYRK2 CDK1 SPAG5 POC1B SAPCD2 TRAF5 CBX1 EFTUD2 UBE3D SSRP1 JMJD4 GINS2 GEMIN5 RAI1 ZNF428 HMGA1 FANCM U2AF2 STRBP SMARCA4 INO80E TYSND1 LLGL1 TCF3 TRIB2 SMPD4 MTHFD1 SEPHS1 SMARCB1	up	***
PID_ATR_PATHWAY	0.0001933	0.0028605	0.5188481	0.5648327	1.970381	38	TIMELESS PLK1 CDC6 MCM2 CDC25A ATR SSPO SMARCAL1 MCM7 CLSPN FANCD2 CDC25C TOPBP1 CHEK1 MDM2 RAD9A RPA1 CCNA2 RFC5 CEP164 RAD51 FBXW11	up	**
LE_EGR2_TARGETS_UP	0.0000062	0.0001395	0.6105269	0.4734955	1.969575	96	HMGA2 KIF20A CCNB1 SOX2 UBE2T IQGAP3 PLK1 CDCA8 ECT2 CCNB2 FIGNL1 UHRF1 MCM4 PRC1 TNC BZW2 KIF23 MKI67 BUB1 TOP2A AURKA KIF2C MCM7 RRM2 KIF11 LMNB1 DNAJC9 MAD2L1 INCENP CKS1B CXCL14 NUSAP1 CDK1 TNFRSF21 BIRC5 NAV2 EZH2 KIF22 SLC22A23 MARCKSL1 CDC7 CDC20 MCM5 MARCKS NT5DC2 CCNA2 RFC5 RAD51	up	***
HORIUCHI_WTAP_TARGETS_DN	0.0000000	0.0000000	0.8012156	0.4148133	1.969487	280	HMGA2 DKK1 TRIP13 DDX11 FOXM1 HELLS KIF20A HJURP TROAP BUB1B NEK2 CCNB1 PBK KIF18B NDC80 DEPDC1 TTK CDCA2 RACGAP1 GTSE1 KIF14 ANLN ASPM MSTO1 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 TPX2 CCNB2 UHRF1 TYMS MYBL2 PRC1 NCAPD2 COQ3 LDHB MELK HMMR KIF23 CEP55 MKI67 BUB1 TOP2A DPY19L1 AURKA KIF2C MCM7 CENPW RRM2 FSD1 KIF11 FANCD2 LMNB1 ZNF618 MAD2L1 CKAP2L FBL RAD51AP1 TIMM50 SPC24 PHB RGS4 PSRC1 CKS1B NUSAP1 ASF1B CDK1 BIRC5 ULBP2 GMNN UNG NCAPG PEG10 SPAG5 NLN UQCC2 KPNB1 DLGAP5 SNRPA LMNB2 KIF22 TK1 ENAH SYT1 TWF1 POLD1 CCT7 SULT1B1 CDC20 TMEM106B CENPM HMGA1	up	***
WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP	0.0004455	0.0058557	0.4984931	0.6434981	1.968490	21	PCSK6 KIF20A NEK2 ASPM PRC1 DTL TOP2A RRM2 CDK1	up	**
KOINUMA_COLON_CANCER_MSI_UP	0.0011568	0.0127732	0.4550599	0.6984298	1.964135	15	TYMS CXCL10 TPBG HOXC6 CXCL9 NCAPG PSMB5 ANP32E	up	*
LINDGREN_BLADDER_CANCER_CLUSTER_3_UP	0.0000000	0.0000001	0.7881868	0.4145295	1.963785	274	RHPN2 TRIP13 CDC45 SLFN13 NEK2 CCNB1 CENPF GGCT DEPDC1 TTC39A BRCA1 RACGAP1 E2F8 KIF14 TRAIP PLK1 CDCA8 CENPA PTTG1 CDC6 CCNB2 FIGNL1 MCM4 TYMS CDC25A MYBL2 PRC1 ORC1 COPB2 MCM8 LIG3 MIS18A XPOT ZWINT CDT1 AOC1 CLPTM1L MELK EXO1 KIF23 CEP55 CHAF1A HLTF BUB1 TOP2A AURKA SAE1 KIF2C POC1A CPD RRM2 WDHD1 RAD54L TOM1L1 KIF11 CHAF1B RNFT2 LIG1 ASS1 MAD2L1 RAD18 IDH2 ZNF587 CKS1B NCAPG2 CDKN2C C12orf75 CXCL14 TMEM106C URI1 CDK1 SNX4 UCK2 BIRC5 GMNN E2F1 REEP6 EZH2 MRPS12 RAB11FIP4 PSMC4 MAD2L2 LINC00173 RNASEH2A CCNE1 GNPAT DLGAP5 WDR53 TACC3 MNS1 MORN2 TK1 CENPQ GINS2 CDC7 WDR34 FAF1 FAM136A BCL2L1 MCM6 CKAP2 MCM5 C5orf22 ATAD2 ZNF286A DDAH1 PYCR1 CEP85 GLO1 MSH2	up	***
CHEN_HOXA5_TARGETS_9HR_UP	0.0000000	0.0000016	0.7195128	-0.3630368	-1.963354	205	TBX3 THSD1 THAP9-AS1 BACH1 NEDD9 RCHY1 IER2 CCNL1 EIF5 KLF10 KLF6 HLX CLK1 MCL1 TIPARP BIRC2 ARNTL ATF3 CLK4 MAFF NRBF2 MARK3 AKIRIN1 RABGGTB RSRC2 CDKN2AIP VCPKMT ZNF426 RBM39 RYBP CREM JUN HRH1 JUNB DUSP8 RCAN1 IFRD1 MORC3 TNFRSF9 TNFRSF10B ZNF20 FOS PELI1 CDK17 FOXO3 FOSB ING3 ADPRM TSC22D1 ZCCHC10 CEP76 DUSP5 ZNF136 PPIG GABARAPL1 CRY1 ZNF267 ETS2 ATAD2B GEM INTS6 NEK1 RLF RIPK2 ARIH1 SRSF10 FNBP4 NFKBIA JMJD1C TLK2 ZNF165 C21orf91 C2orf42 FAM13B SFPQ SPATA5L1 PMAIP1 EGR1 DUSP6 CENPC CCNT2 PPWD1 WAC ZNF14 BCL10 TSC22D2 CDK7 PYROXD1 NFIL3 PNRC2 RNF111 TAF1D PTGS2 ZNF331 CASP3 SREK1	down	***
REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	0.0025085	0.0240022	0.4317077	-0.7462576	-1.962220	9	TXNIP TXN FOXO1 FOXO3 KAT2B CREBBP EP300 SIRT1	down	*
WONG_ADULT_TISSUE_STEM_MODULE	0.0000000	0.0000000	0.9969862	-0.3227207	-1.959741	583	CXCL3 RAMP3 SASH1 STAC TEK TSPAN4 PDLIM2 DLC1 TAL1 OSBPL1A KCNA2 GATA2 IL1B TIE1 F2RL3 SNX10 THSD1 ADCY9 GPR65 LRRFIP1 ENG BDNF FYN SHANK3 EGR2 LMO2 BACH1 CAV1 MYADM CITED2 SLC39A8 ESAM MEF2A CASP12 NEDD9 ABCB1 SPCS3 IER2 PDE2A NFIX HBEGF CACNA2D2 LATS2 ENTPD1 EIF1 PLXNA2 ABCG2 CLEC7A GNGT2 AHRR PBX3 ZNF503 ABCG1 KLF10 FOXP1 KLF6 HLX GATA3 NR4A1 ADRB2 IL18R1 SFRP1 PPP1R13B CLK1 ZEB1 BTG3 TXN PDGFA TUBB6 RHOB LRP4 ADARB1 PTPN12 SYNPO PTPN21 KCNMA1 KLF4 AOC3 PEG3 REST KLF9 DAB2 USP2 STK17B THBS1 SOCS2 MYO1B MPL CLIC4 TMBIM1 ITIH5 PDE8A CCL3 CDKN1A CADM1 UBE2E2 ATF3 SELP ID2 PTGER3 PER1 DUSP1 SMAD7 PLEK MATN2 SLC6A6 GNAQ PRDM5 CRIM1 MEDAG VWF PROCR CREBRF SLC8A1 HCAR3 ID4 IL6 PHTF2 KLRB1 SOCS3 MAGI2 RGS18 SLC35E4 JUN MITF STAT4 LTBP2 CTSZ HSPA1B JUNB ARHGEF10 IFNGR1 JAK1 AK1 DUSP8 PPP1R15A PTGER4 FERMT2 DAPK2 PRKCE GRASP GRIK1 CD34 ACOT1 SLC3A2 FOS RHOQ RRAS KLF2 PKD2 FOSB DGKG PKIA ZNF521 TCF4 CD1D GLRA3 TSC22D1 CBFA2T3 MEIS1 GABARAPL1 TOB1 MFNG MACF1 RGS2 LTBP1 TAGLN ETS2 DBNDD2 ICAM1 SESN1 HSPA2 IL18 CPQ SERTAD1 CEBPD MS4A4A CDKN1C ITGAE TRAF1 S100A4 LYSMD3 GLUL LIMCH1 NFKBIA TTC28 KIT TIMP3 SKI LTBP3 MCOLN2	down	***
KEGG_CELL_CYCLE	0.0000029	0.0000694	0.6272567	0.4565291	1.959325	118	CDC45 CHEK2 BUB1B CCNB1 TTK CDK4 PLK1 PTTG1 ESPL1 CDC6 E2F3 TFDP2 CCNB2 MCM4 MCM2 CDC25A ORC1 BUB1 ATR MCM7 MAD1L1 E2F2 PRKDC MCM3 CDC25C CHEK1 ORC6 MAD2L1 MDM2 PKMYT1 SKP2 CDKN2C ANAPC5 CDK1 E2F1 ANAPC7 MAD2L2 CCNE1 CDC23 HDAC1 FZR1 ANAPC1 CDC7 CDC20 MCM6 MCM5	up	***
TIAN_TNF_SIGNALING_VIA_NFKB	0.0014928	0.0156388	0.4550599	-0.5576810	-1.958536	24	CXCL3 NFKB1 CXCL2 IL6 CD83 REL TNFRSF9 GFPT2 CCL20 TRAF1 NFKBIA ZFP36 IRF1 PTGS2 RELB TNFAIP2 TNFAIP3	down	*
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_23	0.0018161	0.0183301	0.4550599	-0.6012502	-1.957574	18	DDX6 PAFAH1B2 CBL PICALM FLI1 MAML2 SDHD	down	*
SANSOM_APC_TARGETS_REQUIRE_MYC	0.0000000	0.0000012	0.7337620	0.4275960	1.957521	198	BUB1B TIMELESS PHGDH METTL1 CDK4 GTSE1 POLE KNOP1 SHMT2 NME1 WDR62 SMARCC1 QTRT1 SLC29A2 GTPBP3 MCM7 RAD54L MCM3 SOX4 SMYD5 SIDT1 FBL GAS8 HES6 CAD FADS2 THOP1 WDR54 GNPNAT1 SAPCD2 CENPP RNASEH2A ANKRD39 GIPC1 DENND6B TELO2 POFUT1 NFS1 ADAT1 LMNB2 TRIM9 TUBB2A HIRA EPHB2 DPH2 TK1 DTYMK MYBBP1A STOML1 ATG9B GINS2 GEMIN5 SRD5A3 ZSWIM3 NRF1 SLC1A3 CCT7 WDR34 AAAS RRP9 RAI14 LANCL2 PTHLH MYEF2 LHPP DDAH1 NTMT1 HAGHL CDC42BPA TMEM141 RNF157 WDR4 FARSB RASSF4 ZMYND19 POLR1A SMPD4 TP53 SIGMAR1 PTOV1 NELFA PPP1R14B ASCL2 RANGRF ROR2 ALKBH2 USP20 MED22 MUS81 NSUN5 SRM ATRIP TMPO NHP2 DUS3L RCC2 D2HGDH SHMT1 PCBP4 LRP8 ZNF790 CCDC86 TP53RK LFNG DDX49	up	***
BIOCARTA_DC_PATHWAY	0.0037991	0.0326708	0.4317077	-0.6851702	-1.955041	11	CD5 CD33 ANPEP IL10 ITGAX CD7 CSF2 IL5	down	*
CHEN_ETV5_TARGETS_SERTOLI	0.0037980	0.0326708	0.4317077	-0.5999730	-1.954757	17	THBD CD36 ARSB CLEC7A CD53 PLEK IL6	down	*
REACTOME_IRAK4_DEFICIENCY_TLR2_4	0.0028367	0.0259723	0.4317077	-0.7431339	-1.954007	9	MYD88 CD36 LY96 TLR4	down	*
WHITFIELD_CELL_CYCLE_G2	0.0000007	0.0000202	0.6594444	0.4418132	1.953193	149	UNC5CL HJURP TFAP2A CHEK2 POLQ MND1 TTF2 NDC80 PIF1 CDCA2 ANLN TRAIP STIL CDCA8 AURKB ESPL1 CCNF RCCD1 WDR62 MELK KIF23 RHNO1 TOP2A CENPL TMEM132A KIF11 FANCD2 LMNB1 CDC25C MAD2L1 CKAP2L TRMT2A ZNF587 DET1 ENTPD5 PSRC1 CDKN2C CXCL14 NUSAP1 CBX5 CDK1 AP3D1 NEIL3 TNPO2 FADD RANGAP1 ARHGAP11B TUBB2A KIF22 FZR1 KIF20B SAP30 BRD8 VPS25 CDR2 CKAP2 DHX8	up	***
MORI_MATURE_B_LYMPHOCYTE_UP	0.0000454	0.0008212	0.5573322	-0.4260302	-1.951792	78	GPR65 TMOD3 SAMHD1 GGA2 MAP3K8 MS4A1 LCP1 ADRB2 MCL1 ID3 PTPRC SELL RAP1GDS1 HLA-DQA1 FAM76B ADD1 CMTM6 CNOT6L PHTF2 CTSS ETS1 IFNGR1 CD83 IRF8 RAB8A PXK MORF4L1 CD74 PEA15 MACF1 IGKV1D-39 PIP4K2A	down	***
STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN	0.0002628	0.0037584	0.4984931	0.5636474	1.949564	37	MCM10 SLC27A2 CDC6 MCM2 CDC25A DTL WDHD1 SKP2 NCAPG2 POLE2 FEN1 ULK1 GINS2 MCM6 RAI14 MCM5 GINS3 CHRNA5 ATAD2 CAP2 ZWILCH CELSR2	up	**
REACTOME_G2_M_CHECKPOINTS	0.0000025	0.0000618	0.6272567	0.4532974	1.948301	121	CDC45 MCM10 CHEK2 CCNB1 BRCA1 GTSE1 CDC6 CCNB2 RBBP8 MCM4 MCM2 CDC25A ORC1 MCM8 EXO1 TP53BP1 RHNO1 ATR MCM7 CLSPN MCM3 CDC25C TOPBP1 CHEK1 ORC6 PSMD4 PKMYT1 BRIP1 BLM CDK1 PSMB5 DNA2 PSMC4 PSMA5 RAD9A PSME2 PSMD2 CDC7 RAD50 PSMB3 RPA1 UBE2V2 MCM6 MCM5 UIMC1	up	***
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	0.0011131	0.0124145	0.4550599	-0.5117263	-1.946944	31	CLEC1B FYN CDC42 RHOA RHOB FCER1G PIK3R5 RAC2 RHOG PIK3R1 PLCG2 VAV3 LAT	down	*
BIOCARTA_IL10_PATHWAY	0.0046883	0.0386328	0.4070179	-0.6578808	-1.944916	12	IL1A HMOX1 IL10 STAT5A IL6 JAK1	down	*
GESERICK_TERT_TARGETS_DN	0.0025579	0.0242858	0.4317077	-0.5883635	-1.944512	19	EGR2 HBEGF BTG2 KLF10 NR4A1 KLF4 KLF9 JUNB FOSB DUSP6 ZFP36 HEY1 NFIL3 NFKBIZ	down	*
NIKOLSKY_BREAST_CANCER_6P24_P22_AMPLICON	0.0026504	0.0248438	0.4317077	-0.5761379	-1.943516	20	PHACTR1 GFOD1 TBC1D7 RNF144B RANBP9 RNF182 ID4 KIF13A CD83 NOL7 NUP153 MCUR1 TPMT	down	*
SANA_TNF_SIGNALING_DN	0.0000734	0.0012549	0.5384341	-0.4311986	-1.940885	71	EPAS1 SASH1 ACE PECAM1 LYVE1 MMRN1 EMCN LDB2 CALCRL SRSF7 GIMAP6 TXNIP ANXA1 VWF ARHGDIB CABLES1 KCTD12 RHOJ PALMD CD34 ZNF521 CTNNAL1	down	**
LIM_MAMMARY_LUMINAL_MATURE_DN	0.0000296	0.0005687	0.5756103	-0.4099963	-1.939732	89	WTIP DPYSL2 LPL AQP9 TGFBR3 GAS6 FAM49A LTBP4 SFRP1 TUBB6 EPB41L2 FABP5 TLE4 FOXO1 SORBS1 CASP1 NES DAB2 VIM RECK FRMD4A RASL12 FOXN3 KCTD12 ETS1 MAP4K4 GYPC ZNF521 CYGB IRS2 MOB3B SPARCL1	down	***
CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP	0.0027514	0.0254873	0.4317077	-0.5744223	-1.937728	20	CD55 INSIG1 SRSF7 HSPE1 ACSL3 JUNB ACSL1 FOSB HSPA2 NEK3	down	*
REACTOME_DEFECTIVE_GALNT3_CAUSES_FAMILIAL_HYPERPHOSPHATEMIC_TUMORAL_CALCINOSIS_HFTC	0.0003645	0.0050191	0.4984931	0.7521983	1.937058	12	MUC5B MUC13 MUC4 MUC16 MUC5AC MUC20 MUC6	up	**
REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	0.0033480	0.0299100	0.4317077	-0.6127168	-1.935595	16	HES1 RBPJ MAML2 NOTCH1 KAT2B CREBBP FLT4 SNW1 HEY1 EP300	down	*
HOLLERN_EMT_BREAST_TUMOR_UP	0.0000060	0.0001375	0.6105269	-0.3850968	-1.932152	123	TSPAN4 ADPRH HHEX CDH13 TGFBR2 SCARA3 HSPG2 NAAA ITGA5 CSGALNACT2 TTYH2 HLX IL18R1 SPTBN1 ZEB1 SPI1 EPB41L2 ST3GAL2 DAB2 STK17B MARVELD1 GPR85 VIM AXL MATN2 MEDAG NRROS EMP3 ARL6IP5 PLEKHA3 RGS18 APBB2 GLIPR1 SNX9 FLNC TIMP2 APBB1 AOX1 GNB4 FCGRT PLA2G15 FAM167B OSR1 TRAF1 S100A4 NRP2 ZFPM2	down	***
WORSCHECH_TUMOR_REJECTION_UP	0.0003968	0.0053695	0.4984931	-0.4740785	-1.931850	44	CXCL3 IL17RB IL1A IL1B MNDA CCRL2 CLEC10A BCL2A1 MSR1 CCL22 CXCL2 TLR4 KLRD1 IL7R	down	**
PID_ATM_PATHWAY	0.0006300	0.0076761	0.4772708	0.5869763	1.931772	28	CHEK2 BRCA1 RBBP8 CDC25A TP53BP1 FANCD2 CDC25C MDM2 BLM DCLRE1C RAD9A RAD50 XRCC4 UIMC1	up	**
MORI_PRE_BI_LYMPHOCYTE_UP	0.0000730	0.0012516	0.5384341	0.4936599	1.931108	68	HJURP NDC80 PHGDH CDCA7 TTK RACGAP1 E2F8 CCNB2 MCM2 PRC1 GRB7 DTL MELK SMARCC1 MKI67 TOP2A AURKA MCM7 RRM2 CDCA5 LMNB1 LIG1 HSPBP1 CKS1B CDK1 PSAT1	up	**
REACTOME_G1_S_SPECIFIC_TRANSCRIPTION	0.0005599	0.0070093	0.4772708	0.5924105	1.929781	27	CDC45 CDC6 TFDP2 TYMS CDC25A ORC1 CDT1 RRM2 CDK1 E2F1 CCNE1 TK1 HDAC1 LIN37	up	**
REACTOME_CELL_CYCLE_MITOTIC	0.0000000	0.0000000	0.8870750	0.3889002	1.928369	455	FOXM1 CEP72 KIF20A CDC45 MCM10 BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 PRIM2 TUBB2B GINS1 CDK4 GTSE1 POLE CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 E2F3 TFDP2 CCNB2 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 ORC1 DYNC1I1 MCM8 GINS4 NCAPD2 ZWINT CDT1 DCTN2 SPDL1 HAUS5 CEP250 HMMR BTRC KIF23 KNTC1 BUB1 TOP2A CENPL AURKA NUP155 ODF2 POLA2 POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 E2F2 RRM2 LPIN3 CDCA5 MCM3 LMNB1 CDC25C LIG1 ORC6 MAD2L1 PSMD4 CENPO SPC24 AKT2 PKMYT1 MNAT1 SKP2 INCENP CKS1B NCAPG2 CDKN2C ANAPC5 CDK1 POLE2 CENPJ CENPH BIRC5 GMNN E2F1 NCAPG PSMB5 DNA2 KIF2A ANAPC7 FEN1 NUP205 DYNLL2 PSMC4 CENPP FGFR1OP KPNB1 RANGAP1 MZT2A MZT2B CEP63 CCNE1 CEP192 CDC23 TUBG1 PSMA5 NINL TUBB2A PSME2 TUBA3D TK1 TUBA8 CENPQ HDAC1 ESCO2 GINS2 FZR1 LIN37 ANAPC1 POLD1 PSMD2 NUP85 PPME1 CDC7 CENPK CKAP5 PSMB3 CDC20 CENPM TUBG2 AAAS RPA1 CHMP4C CDK5RAP2 MCM6 DYNC1LI2 CENPT MCM5 HAUS6 GINS3 RCC1 HAUS4 PSMB4 CEP152 NUP62 ALMS1 CCNA2 PRIM1 BANF1 ANAPC2 RFC5 TUBGCP4 CEP164 LPIN1 TUBA4B ZWILCH SEC13 FBXW11 NME7 CHMP2A SMC2 MAU2 CENPE TP53 GOLGA2 LEMD2 CDC25B UBE2C NCAPD3 TUBA1C PPP2R5D NUP210 CLASP1 NUP93 FBXL18 NCAPH CEP290 CHMP6 DYNC1H1 PLK4 AKAP9 PCNT DSN1 CDK11B RBL1 PPP2R5E FBXO5 PSMB10 LCMT1 TUBGCP2 PSME1 NSL1 TMPO	up	***
RICKMAN_HEAD_AND_NECK_CANCER_D	0.0005668	0.0070793	0.4772708	0.5918934	1.928096	27	MUC5B LTF TF CCL19 ZG16B PROM1 TFF3 AGR2 BPIFB1	up	**
REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES	0.0064688	0.0492613	0.4070179	-0.6257143	-1.926456	14	CAV1 FOXO1 KLF4 CDKN1A BTG1 FOXO3 SMAD2 RBL2 SMAD4 CDKN1B	down	*
ROSS_AML_WITH_MLL_FUSIONS	0.0002104	0.0030898	0.5188481	-0.4312103	-1.926068	65	FBP1 SNX10 ADCY9 LY86 GGA2 SPG21 PBX3 ANXA5 DACH1 SIRPA CES1 SRGN SOCS2 TPP1 ITGAX ALOX5AP TDRD7 HEXB HK3 APH1B ALDH3B1 NKG7 WHAMMP3 MBNL1 SCPEP1 RNH1 FEZ1	down	**
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE	0.0006312	0.0076761	0.4772708	0.6203623	1.925641	22	HJURP RUVBL1 CENPA MIS18A CENPL CENPW CENPO CENPH CENPP CENPQ CENPK CENPM CENPT	up	**
KEGG_PYRIMIDINE_METABOLISM	0.0000164	0.0003391	0.5756103	0.4653852	1.923509	90	PRIM2 POLE TYMS UMPS DPYS NME1 POLR3A POLA2 POLD2 RRM2 NT5C1B ENTPD6 NME5 POLR3C CAD ENTPD5 POLE2 UCK2 NUDT2 POLR3K POLR1C UCKL1 POLR2H UPP2 DHODH TK1 DTYMK POLD1 NT5M ENTPD8 POLR2J ENTPD3 POLR2J3 POLR2I NME1-NME2 PRIM1 CANT1 POLR3B NME4 NME7 POLR1B POLR1A	up	***
TIAN_TNF_SIGNALING_NOT_VIA_NFKB	0.0028524	0.0260295	0.4317077	-0.5697651	-1.922018	20	GATA2 INSIG1 KLF10 KLF6 NR4A1 TIPARP TPTEP1 JUN JUNB PPP1R15A FOSB PDE8B EGR1	down	*
FISCHER_G1_S_CELL_CYCLE	0.0000008	0.0000218	0.6594444	0.4291411	1.918044	165	MNX1 HELLS C1GALT1 MDM1 MCM10 BRCA1 CDCA7 E2F8 POLE YEATS4 CDC6 RBBP8 MCM2 CDC25A DLGAP1 DTL TMCC1 MAP2K6 CDT1 TRIM45 CASP2 EXO1 CHAF1A PAQR4 POLA2 E2F2 CLSPN RRM2 WDHD1 PASK MCM3 CHAF1B TOPBP1 CHEK1 DSCC1 BRIP1 BLM RNPC3 POLE2 GMNN E2F1 UNG FEN1 EZH2 RECQL4 ABHD4 FANCG CCNE1 MNS1 CENPQ GINS2 CDC7 USP18 AP3M2 MCM6 MCM5 ANKRA2 ANK3 ATAD2 MSH2 PRIM1 BBX ABHD10 RAD51 ZMYND19 WDR76 ADCY6	up	***
TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C	0.0000000	0.0000000	0.8390889	0.3917117	1.915998	389	TRIP13 SLC16A14 FOXM1 CEP72 HELLS FAM81A TICRR PARPBP ZNF273 ZMYND8 BUB1B PPIP5K1 NEK2 UGT8 CCNB1 CENPF CPSF6 CMTM1 RAB3IP PHGDH CDCA7 CDCA2 CDK4 PRR15L GTSE1 DBF4B KIF14 POLE STIL PLK1 AURKB CENPA FIGNL1 CDC25A MYBL2 XRCC2 CCNF DTL MCM8 MARVELD3 XPO5 MIS18A ZNF107 TTLL4 MELK SPDYE3 MKI67 KIF15 AURKA KIF2C CLSPN MPHOSPH9 RRM2 MMS22L HOOK1 RAD54L KLHDC4 KIF11 PASK FANCD2 GPSM2 MCM3 LMNB1 PFN2 LIG1 BRI3BP CC2D1A CKAP2L CENPO LRRC37A4P SPC24 PKMYT1 BRIP1 GNPDA1 DPY19L1P1 SKP2 PSRC1 PTPN3 NUSAP1 ASF1B TNFRSF21 CENPJ DIDO1 UNG L2HGDH DNA2 ANAPC7 FEN1 LRRC37A2 ZNF623 PRR22 PA2G4 KPNB1 NRGN MZT2B DCLRE1C FOXRED1 MNS1 ARHGAP32 RAD51D COPS7B ZNF544 ENAH PDRG1 ITFG2 KIF20B TSEN54 ESR1 DENND5B ATAD5 GOLM1 KLHL23 ZNF202 SH3GLB2 HAUS6 RAB3D GINS3 PIGX HAUS4 CEP152 STRBP CEP85 ALMS1 LRP11 CCNA2 CANT1 DENR SHCBP1 NAV1 PCBD2 CCDC9 RAD51 PPP6R2 MCU ARHGAP11A OXCT1 ZNF700 ZMYND19 MLLT1 SNRNP70 POMK ZNF91 CENPE SMPD4 ESPN SYNE2 ZNF681 FUT10 ADCK2 NUP210 DNM1L C4orf46 MTG2 PRKAG1 ERLIN1 XPO6 FGFBP3 MORN4 MED22 MIOS SHQ1 PLK4 PPARGC1B PRPF19 LPCAT1 ABHD2 TNPO3 KRIT1 TOMM40 SNHG17	up	***
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	0.0000003	0.0000096	0.6749629	-0.3589312	-1.915772	187	DENND5A LTA4H SAMHD1 CITED2 NR3C1 WBP4 ATP2B1 LATS2 RNF125 KLF6 ZYG11B PPP3CC FLI1 SDCBP DENND6A SOCS2 ELK3 ARL4A PPP2R5C IL7R FAM76B CNOT6L VCPKMT TBC1D5 ELF1 PHTF2 DCTN6 NEK7 ESD RAB8B PSMA1 LRCH1 STAT4 NSMCE2 ETS1 ARHGEF10 PIK3R1 UBAC2 GPR183 IDS PTGER2 MALT1 TPP2 NAA30 CELF2 GPRIN3 PELI1 CDK17 HIVEP2 ZFAND6 NUP153 ATP6V1A HBP1 ANKRD12 GPR18 PDE4B MBNL1 LDLRAD4 SESN1 SEC63 PIP4K2A CXCR4 SIK3 ZBTB25 JMJD1C DOCK10 B3GNT2 C21orf91 EVI5 FAM8A1 CD69 SLC25A40 MAN1A1 MAP3K1 TRAT1 ITGA6 DUSP22 JARID2 IRF4 AKAP13 TTC39B NFKBIZ	down	***
WALLACE_PROSTATE_CANCER_RACE_UP	0.0000000	0.0000003	0.7614608	-0.3486047	-1.915674	258	RAMP3 CD52 DLC1 PECAM1 GPR65 THBD FYN SOX17 C5AR1 BCL2A1 GIMAP6 CD1C EOGT CD8A TMX4 DNASE1L3 WNT2B OLFML2A ANPEP RNASE1 MS4A1 SERPINB9 STOM CD93 TFEC SRGN CD37 GPM6A CNN1 FLI1 EVI2B TLE4 STK17B CLDN5 LY96 ITIH5 LAPTM5 COTL1 PTPRC SELL SELP CCL4 CD53 PRF1 FCER1G ALOX5AP PLEK EVI2A IL7R HLA-DQA1 MMP19 NCKAP1L PDK4 CREM CTSS CD48 C1QA RAC2 CCR7 GLIPR1 CD83 IRF8 GMFG GPR183 CELF2 IGKV3-20 RUNX3 ICAM2 NKG7 CD86 IRS2 GPR18 PLEKHO2 ETS2 IGKV1D-39 SYT11 TRAC SF1 CEBPD MS4A4A CXCR4 CTSC CD1E DOCK10 GPR171 SAMSN1 THEMIS2 IL16 LYZ CSF2RB PEX14 C1QB NR4A2 ITGAL MICAL1 CD69 GNG11 LAMP3 HLA-DRB1	down	***
KEGG_BASE_EXCISION_REPAIR	0.0005072	0.0065890	0.4772708	0.5714806	1.915139	32	POLE LIG3 SMUG1 POLD2 LIG1 XRCC1 PARP1 POLE2 UNG NEIL3 FEN1 POLL MBD4 POLD1 POLB MPG NEIL1 APEX1 PARP2	up	**
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP	0.0000001	0.0000048	0.6901325	-0.3559055	-1.914846	192	RAB11FIP1 CXCL3 EREG IL1A IL1B CD44 PAFAH1B2 BCL2A1 IL1RN TRIB1 IER2 ABCG2 BTG2 KLF6 RNASE1 PTX3 HNRNPDL SPRY2 MCL1 TIPARP KLF4 KLF9 DAB2 CCL3 CDKN1A CXCL2 ATF3 CCL4 DUSP1 ARL4A CA1 MAFF ADD1 TBC1D5 HCAR3 AREG IL6 SGK1 IL2RB SLCO2B1 SF3B1 JUN TREM1 JUNB PPP1R15A PTGER4 FERMT2 BAG5 FBXO11 CD83 GPR183 ATL2 DLEU2 FOS ADNP2 RHOQ KLF2 FOSB FLNC EPB42 EHD1 TCF4 COL15A1 SOD2 SBSPON RGS2 PDE4B ETS2 ICAM1 IER5 CDC42EP3 SIK3 CCR9 PSME4 NFKBIA NUP160 SPSB1 EGR1 NR4A2 HIPK1 SSB FUS ZFP36 YRDC	down	***
AMIT_SERUM_RESPONSE_120_MCF10A	0.0001431	0.0022069	0.5188481	-0.4409075	-1.914211	62	CD55 SOWAHC BMP2 SIK1 NEDD9 CLCF1 KLF10 MCL1 SETD3 KLF4 PLAUR ID3 ID2 MAFF RYBP BCAR3 JUNB FERMT2 SKIL PDZD2 FEM1B IRS2 PIM1 STX12 ETS2 PDLIM5 CDKN1C EDN1 SPHK1 YRDC IFIT5 DAPP1	down	**
NUYTTEN_EZH2_TARGETS_DN	0.0000000	0.0000000	1.1421912	0.3769613	1.913850	884	CPS1 RIBC2 SLC16A14 PTGES FOXM1 SLC16A9 KIF20A HJURP CDC45 TICRR DNAH2 PARPBP MCM10 FANCI TROAP NEK2 CCNB1 CENPF TIMELESS FLVCR1 UBE2T PAGR1 GBAP1 PDCD2L PSPH DNAJC22 MND1 PBK KIF18B TTF2 NDC80 DEPDC1 BRCA1 PHGDH DEPDC1B CDCA7 C12orf66 CREB3L4 TTK MUC5AC RACGAP1 IQGAP3 E2F8 GTSE1 SLC27A2 KIF14 L3MBTL1 CCDC14 TRAIP NIPSNAP1 ASPM STIL SAYSD1 PLK1 NUF2 IFT27 CDCA8 AURKB CENPA PTTG1 ALDH18A1 ECT2 PAK6 TPX2 CCNB2 UHRF1 MCM4 MCM2 RAD54B TYMS SP5 CDC25A UMPS COCH PRC1 ANKRD36B DTL TDRKH MCM8 MIS18A MAP2K6 GINS4 NCAPD2 ZWINT MRPS35 CDT1 CCT2 LSM5 MAGEF1 HAUS5 MANSC1 C5orf34 NR2C2AP TMEM41A HMMR EXO1 NUDT1 MAP7 NLE1 KIF23 CEP55 CHAF1A SYTL2 RPL39L RPAP1 F2RL1 EMC9 KIF15 TRIM29 KNTC1 BUB1 FANCA TOP2A CENPL PUS7 AURKA NUP155 REC8 P4HTM ODF2 SAE1 GTPBP3 LARS2 KIF2C MCM7 E2F2 CENPW POC1A CLSPN ABCC5 RRM2 WIPI2 MMS22L CDCA5 WDHD1 SGPL1 HOOK1 RAD54L EIF2AK1 FANCD2 TRPT1 LMNB1 CDC25C PPP1R35 BRI3BP SIDT1 TOPBP1 SPINT1 THYN1 CKAP2L NFYA FBL RAB13 RAD51AP1 EHHADH XRCC1 PIH1D1 THAP10 KHK SPC24 DSCC1 CAD RAD18 INPP4B BLM CCDC136 COMMD4 NOL3 ZNF587 SLC45A3 CCDC138 PSRC1 GEMIN4 THOP1 CASP6 CKS1B EFCAB11 PRRT3 CMAS CDK1 CEP97 EXOSC2 CENPJ DIDO1 BCAS4 RFWD3 CENPH BIRC5 ATP6V0E2-AS1 ABHD17C CCM2 C1orf112 WDR54 GMNN DNA2 MKRN1 PACSIN1 DHX33 LARP1 NEIL3 SSX2IP EZH2 DYNLL2 SPAG5 RAB11FIP4 ETFB MTBP RECQL4 FGFR1OP RNASEH2A RNF44 MYO19 FANCG IFI27L2 UBFD1 CRLF1 CCNE1 GNPAT DLGAP5 SCLY ARHGEF16 SPG7 SLC26A2 GALK2 CTSV TACC3 KIF22 MRPL11 USB1 TRIM37 SSRP1 ZNF544 DTYMK C1orf131 CHTF18 CENPQ JMJD4 ESCO2 GINS2 SPAG1 KIF20B SPA17 LRRC20 BCL2L12 POLD1 MAGOHB TMEM30B CDC7 SLX4IP ETV4 SASS6 GEMIN6 KLHDC3 EFCAB7 BRD8 CDC20 ORMDL2 CENPM WDR34 EFHC1 GPATCH4 CDR2 CDK5RAP2 MRPL24 ASRGL1 HOXA3 MRPS33 PRMT1 ANKRA2 HEATR1 C1orf56 HAUS6 RABEPK ADD3 OVOL2 HAUS4 PSMB4 NT5DC2 ATAD2 TCERG1 COPZ1 PATZ1 EPCAM DPH5 DDAH1 SPON2 SH3D21 CATSPER1 GLIS3 CCNA2 PRIM1 DZIP3 PRR11 TIGD2 BANF1 SHCBP1 TMEM141 RFC5 SYBU WDR4 ELOVL4 HOOK2 LPGAT1 RAD51 NBR1 MTIF3 ZWILCH CDK5 AGBL5 WDR76 SLC12A2 ARHGEF39 TARBP2 TONSL CPT1C GMPR2 TMEM260 CENPE RPP25L POP4 SWI5 CMTM8	up	***
TERAMOTO_OPN_TARGETS_CLUSTER_1	0.0022063	0.0215903	0.4317077	-0.6987373	-1.912071	10	SC5D INSIG1 HMGCR TFRC	down	*
REACTOME_MITOTIC_PROMETAPHASE	0.0000004	0.0000128	0.6749629	0.4252564	1.911688	176	CEP72 BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TUBB2B CEP70 PLK1 NUF2 CDCA8 AURKB CENPA CCNB2 DYNC1I1 NCAPD2 ZWINT DCTN2 SPDL1 HAUS5 CEP250 KNTC1 BUB1 CENPL ODF2 SFI1 KIF2C MAD1L1 CDCA5 MAD2L1 CENPO SPC24 INCENP CDK1 CENPJ CENPH BIRC5 NCAPG KIF2A DYNLL2 CENPP FGFR1OP RANGAP1 MZT2A MZT2B CEP63 CEP192 TUBG1 NINL TUBB2A TUBA3D TUBA8 CENPQ NUP85 CENPK CKAP5 CDC20 CENPM TUBG2 CDK5RAP2 DYNC1LI2 CENPT HAUS6 HAUS4 CEP152 ALMS1 TUBGCP4 CEP164 TUBA4B ZWILCH SEC13 NME7 SMC2 CENPE TUBA1C PPP2R5D CLASP1 NCAPH CEP290 DYNC1H1 PLK4 AKAP9 PCNT DSN1 PPP2R5E TUBGCP2 NSL1	up	***
YAGUE_PRETUMOR_DRUG_RESISTANCE_DN	0.0056239	0.0443564	0.4070179	-0.6699384	-1.911579	11	TNS1 FRMD4A DSE DCHS1 LTBP2	down	*
SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP	0.0000796	0.0013444	0.5384341	-0.4203871	-1.910597	74	CAT CASP9 TACC1 TRAF6 HNRNPDL MPHOSPH6 LAMTOR3 HNRNPU UBE2D3 TXN CASP1 PTPRC CUL5 SMNDC1 CTSS JAK1 TCP1 USP7 APBB1 PPP3R1 SOD2 CCR1 GPX3 HSP90AA1 UBE2D1 HNRNPK KPNA4 GLRX2 HAT1 CENPC ATF2 UBE3A UBE2N CUL2 ATF6 USP33 UBE2D2 RANBP2	down	**
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP	0.0000000	0.0000005	0.7477397	0.4045139	1.908618	268	CEP72 SLC26A4 EPN3 PDCD6 TTF2 BET1 LHB UBE2Z SNF8 NDUFS6 EXOC3 COX11 PVT1 INTS1 CYP3A5 NME1 MICALL2 RUVBL2 OSBPL2 SDHA PON3 AP4M1 GPER1 WDR3 IRF3 MAD1L1 TRRAP WDHD1 ZNF146 LIG1 BRD9 SARS2 ZNHIT1 ACSF2 LRRC37A4P SPAG8 PHB CNOT3 PON2 CMAS NSF KCTD7 ZNF652 ARPC1A VPS28 GIPR ZNF419 SNAPC1 TMEM8B PRPF6 SLC25A13 TAF6 MRPS12 CBX1 UCKL1 DDT ZNF623 ZKSCAN5 KPNB1 TPD52L2 G6PC3 ZGPAT ARFRP1 DLGAP5 COA3 AARSD1 XYLT2 PLEKHG3 LMTK2 CLTA ASNS EPN1 STRN4 TSTA3 LRRC59 ACLY PPP1R3D GID8 PRMT1 NOSIP SNX11 SLC1A5 PRKD2 WDYHV1 EIF3K U2AF2 NUP62 ZNF580 AP2S1 PMS2P1 RCN3 SNRPD2 PAK4 NBR1 ARHGAP5 RSAD1 SNRNP70 ZNF573 NUBPL NMT1 FIS1 FBXO34 TAF4 RASA4 NPR2 PPP2R5D SPATA20 SS18L1 PCTP CYHR1 LUC7L3 PPP1R13L PDK2 UTP18 LPCAT1 PNPO LAMA5 ASL TCFL5 PARP4 NDRG1 PLOD3 CRCP SLC12A9 CABYR BECN1 PSMD8 EEF1D RGP1 ZNF460 HIF1A SNX6 GYS1 MRPL13 MPP2 PLEKHA4 TUG1 ZC3H3 ARL17A GRWD1	up	***
LINDSTEDT_DENDRITIC_CELL_MATURATION_A	0.0002391	0.0034557	0.5188481	-0.4467026	-1.908602	57	IL1B IL1RN SCARF1 PLA2G7 ENTPD1 SLC7A11 TFEC CD58 CCL3 CXCL2 CCL4 PLEK INHBA IL7R HCAR3 IL6 CREM CD48 STAT4 PTGER4 MALT1 SLC3A2 SOD2 KYNU CCL20 ICAM1 RTN1 RAB5A EDN1 TNFSF9 CSF2	down	**
PID_PLK1_PATHWAY	0.0003179	0.0044188	0.4984931	0.5394829	1.906600	41	KIF20A BUB1B CCNB1 NDC80 PLK1 ECT2 TPX2 PRC1 BUB1 AURKA ODF2 SSPO CLSPN CDC25C SPC24 INCENP PAK1 CDK1 KIF2A TUBG1 NINL FZR1 CDC20	up	**
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP	0.0005526	0.0069333	0.4772708	-0.4677711	-1.906148	44	CAT SPCS3 LCP1 SRGN LAPTM5 CD302 ALOX5AP GCA LIN7A BTG1 TRGC2 PTGER4 CST7 ALDH3B1 NKG7 SELPLG CXCR4 ICAM3 SAMSN1 LYZ FNBP1 S100A8	down	**
BILBAN_B_CLL_LPL_DN	0.0005512	0.0069317	0.4772708	-0.4837305	-1.905320	38	MNDA FYN SRSF7 CCNL1 ANXA1 EIF4A1 KLF4 ID2 DUSP1 JUNB FOS BIN2 RGS2 ACAP2 FNBP4 KLRK1 SFPQ PMAIP1 DUSP22 ARGLU1 PNISR FGL2 PRNP CAPN3	down	**
REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE	0.0003160	0.0044061	0.4984931	0.5418639	1.904466	40	BRCA1 RBBP8 XRCC2 EXO1 RHNO1 ATR TOPBP1 CHEK1 RAD51AP1 BRIP1 BLM DNA2 RAD9A RAD51D RAD50 PALB2 RPA1 RFC5 RAD51 RAD1 TOP3A ATRIP RMI1 RMI2 RAD51B RFC3 BARD1 RFC4	up	**
BIOCARTA_MCM_PATHWAY	0.0008000	0.0093980	0.4772708	0.6487290	1.904441	18	CDC6 MCM4 MCM2 ORC1 CDT1 MCM7 MCM3 ORC6 CCNE1 MCM6 MCM5	up	**
REACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR	0.0002168	0.0031583	0.5188481	0.4928372	1.903352	63	BRCA1 POLE RBBP8 XRCC2 EXO1 RHNO1 EME1 ATR POLD2 EME2 TOPBP1 CHEK1 RAD51AP1 BRIP1 BLM POLE2 DNA2 RAD9A RAD51D POLD1 SLX4 RAD50 PALB2 RPA1 RTEL1 RFC5 RAD51 RAD1 MUS81 SPIDR TOP3A ATRIP RMI1 POLD3 RMI2 RAD51B RFC3 BARD1 POLE4 RFC4	up	**
VANTVEER_BREAST_CANCER_METASTASIS_DN	0.0000127	0.0002676	0.5933255	0.4429935	1.899430	116	TRIP13 CA9 HJURP CP CENPF NDC80 DEPDC1 CDCA7 KIF14 TSPYL5 GMPS ASPM CENPA ECT2 CCNB2 PRC1 CD163L1 DTL MELK BUB1 AURKA RRM2 TMEM45A GPSM2 ORC6 MAD2L1 PFKP NUSAP1 IGFBP5 BIRC5 EZH2 RAB6B DIAPH3 INTS7 DLGAP5 CTSV TK1 KIF21A ASNS PSMD2 GNAZ	up	***
REACTOME_INTERLEUKIN_1_PROCESSING	0.0030934	0.0279060	0.4317077	-0.7877707	-1.897957	7	IL1A IL1B CASP1 NFKB1 IL18	down	*
HUANG_GATA2_TARGETS_UP	0.0000091	0.0001987	0.5933255	-0.3768486	-1.896926	128	SLC12A6 GREB1 HHEX MNDA LPXN RAB44 CD44 YPEL5 TGFBR2 TXNIP CD93 SRGN SPI1 CST3 TAPT1 CEBPA CDKN1A ALOX5AP EVI2A N4BP2L1 AFF1 BTG1 EMP3 RAB31 KCTD12 TYROBP RHOG GSTO1 GLIPR1 GMFG PRORSD1P ATP6V0D1 MYL12A DGKG CPA3 DOK3 TGIF1 HBP1 GABARAPL1 TSPO SELPLG TNFAIP8 ACADM KIT GPR171 SAMSN1 IL16 LYZ TMEM50A CDKN1B SH3BGRL3 UBA6 CLEC4E	down	***
SMIRNOV_RESPONSE_TO_IR_2HR_UP	0.0006239	0.0076212	0.4772708	-0.4558779	-1.896482	47	RAB11FIP1 FOSL1 PPM1D SLC7A11 CLK1 CCL3 CDKN1A ATF3 ID2 HCAR3 SGK1 JUN PPP1R15A PTGER4 CD83 NUDT15 TNFRSF10B C16orf72 PIM1 SESN1 IER5 TNFSF9 NUP160 PMAIP1	down	**
GAUTSCHI_SRC_SIGNALING	0.0039847	0.0340554	0.4070179	-0.7413352	-1.896122	8	SMAD6 ID3 ID2 SMAD7 ID4 TGFB1 SERPINE1	down	*
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_DN	0.0006172	0.0075820	0.4772708	-0.4539811	-1.895770	49	CD1C GGA2 ENTPD1 GM2A BTG2 HDC ROCK2 STK17B PTGER3 UTRN RNF24 CPA3 MAP3K2 RGS2 KAT2B CCR6 LDLRAD4 ICAM3 CD1E PDE4A GPR171 HNRNPH1 NR4A2 IRF4 CYP1B1 IVNS1ABP PLXNC1 PTPN22 FGL2 HIP1 CASP8 UGCG	down	**
SCHOEN_NFKB_SIGNALING	0.0019077	0.0190118	0.4550599	-0.4981119	-1.895146	31	IL1A HHEX IL1B PTX3 CSRNP1 KLF4 THBS1 CXCL2 CTSS PTGER4 TNFRSF9 NFKBIA EDN1 CSF2 CDKN1B	down	*
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	0.0000008	0.0000232	0.6594444	-0.3586559	-1.894356	173	LPIN2 DLC1 CD55 LTA4H FBP1 SLC16A4 RAPGEF2 FOLR1 HSD17B11 NEDD4L CITED2 QKI SLC39A8 NR3C1 NEDD9 EDEM1 APOD CYB5A GLS MALL BTG3 TIPARP ARRB1 DAAM2 ZFAND5 PMM1 AQP4 HOPX SFTPD PER1 DUSP1 ELK3 VAMP5 RUFY3 RPS6KA2 SCEL AQP3 NDNF RHOBTB2 SFTPB BMP3 ATP11A ARHGEF10 AK1 NPR1 UNC13B REL GPRC5A PELI1 ALDH3B1 C1orf116 MEIS3P1 APLP2 MR1 GEM ICAM1 SLC34A2 PARM1 CEBPD MEGF9 GPD1L LIMCH1 NFKBIA TTC19	down	***
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	0.0000001	0.0000027	0.7049757	-0.3483072	-1.894080	219	CLEC1B PECAM1 CLEC3B F2RL3 P2RY1 TRPC3 FYN MMRN1 CTSW TBXA2R CDC42 CD9 GAS6 RHOA CD36 RAPGEF4 RAP1A GNGT2 ANXA5 ABHD6 GNG7 CRK SRGN PDGFA RHOB CFD ARRB1 DGKE THBS1 MPL FAM49B ABCC4 SELP FCER1G PLEK GNAQ PIK3R5 GNAI2 VWF TGFB2 PHACTR2 CYB5R1 RAC2 RHOG PIK3R1 PRKCE GRB2 CAP1 YWHAZ TAGLN2 PLCG2 CALM1 PRKCG DGKG DAGLA STXBP3 TGFB1 VAV3 TMX3 CDC37L1 GNAI1 GNG5 GNB4 APLP2 ORM2 GNA13 ACTN2 LAT WDR1 ARRB2	down	***
TOMIDA_METASTASIS_UP	0.0014608	0.0153624	0.4550599	0.6261509	1.891791	20	SLC16A9 CPLX2 TFAP2A PTTG1 ALG3 DNER TUBA3D PSMD2 CXCL1 CKAP4 ECH1	up	*
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN	0.0000000	0.0000000	0.8390889	-0.3244466	-1.891427	392	HMOX1 MS4A7 FCN1 TSPAN4 PECAM1 SPN MNDA LTA4H RDX LY86 PLEKHF2 BACH1 CITED2 QKI MYD88 SLC39A8 APIP TBC1D2 MARCO NR3C1 PDE4C FUCA1 GAS6 TGFBR2 LILRB3 HEG1 GGA2 CCNL1 ZEB2 CD36 DPEP2 ATP2B1 ADA MALAT1 C1orf21 ECHDC1 MAP3K8 PARVG SPIRE1 CSGALNACT2 KLF10 KLF6 STOM LAIR1 C1orf162 RB1 CES1 APOC1 CD37 TIPARP IL10 CCDC82 SGTB KLF4 HAUS2 CTSD PDE8A RBMS1 TLR4 CD302 FRMD4A DUSP1 PINK1 CLIP4 VAMP5 RUFY3 AFF1 LACC1 PRCP KANK1 CREBRF SLC8A1 HESX1 SYNPO2 SGK1 SOCS3 MAML2 OASL LIMD1 KCTD12 HRH1 CELF1 HSPA1B DNASE2 WTAP PTGER4 SNX2 PTGER2 SUCNR1 OCIAD1 SIGLEC1 AGPS KLF2 MBP RIN2 PIK3AP1 SORT1 CCDC152 UBXN2A CHPT1 STXBP3 HNRNPA2B1 FPR2 ZC3H12D GNB4 PLA2G15 ARAP2 GPX3 IL18 PCM1 NBN SETDB2 SEMA4A CEBPD MS4A4A ACAP2 LRP12 CALCOCO2 GIMAP5 SP100 DDX59 METTL7A LYSMD3 CTSC FNIP2 B3GNT2 AIM2 LPAR6 SPATA13 DMXL2 ZFYVE26 SETX HIPK1 FUS NCF1 FPR1 ZFP36 PLEKHA2 SLC26A11 NFAM1 IFIT5 XRN2 CYP51A1	down	***
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	0.0000256	0.0005022	0.5756103	0.4453291	1.891116	106	BUB1B NUP107 CCNB1 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA CCNB2 DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 CDCA5 MAD2L1 CENPO SPC24 INCENP CDK1 CENPH BIRC5 KIF2A DYNLL2 CENPP RANGAP1 TUBB2A TUBA3D TUBA8 CENPQ NUP85 CENPK CKAP5 CDC20 CENPM DYNC1LI2 CENPT	up	***
MCDOWELL_ACUTE_LUNG_INJURY_DN	0.0007700	0.0091035	0.4772708	-0.4766456	-1.890594	39	ACVRL1 CAV1 CDH13 CLEC10A ALAS1 EPB41L3 NFIX LTBP4 ABCG1 TP53BP2 SFTPB ICAM2 SFTPC BMP2K RSU1 C5 HEY1 SLC9A3R2 ADH1B TNFRSF19 DPP4 ANTXR1 FASN SCGB3A2	down	**
SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN	0.0024005	0.0231699	0.4317077	-0.5143857	-1.889596	27	BAIAP2 EIF1 HNRNPA3 KLF9 ATF3 BTG1 ETF1 CELF1 DDX17	down	*
INAMURA_LUNG_CANCER_SCC_UP	0.0005314	0.0068071	0.4772708	0.8482458	1.889493	7	KRT5 SLC2A1 TPX2 TOP2A CDCA5	up	**
BIOCARTA_ATRBRCA_PATHWAY	0.0011675	0.0127891	0.4550599	0.6171563	1.887909	21	CHEK2 BRCA1 FANCA ATR FANCD2 CHEK1 FANCG FANCF RAD9A RAD50 RAD51 TP53 RAD1	up	*
PID_AURORA_B_PATHWAY	0.0005828	0.0072635	0.4772708	0.5494427	1.887270	36	KIF20A NDC80 RACGAP1 CDCA8 AURKB CENPA NCAPD2 KIF23 BUB1 AURKA KIF2C NSUN2 INCENP CBX5 BIRC5 NCAPG	up	**
REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION	0.0031922	0.0286491	0.4317077	-0.5413204	-1.886877	23	IL1A IL1B TXNIP ENTPD1 TXN MEFV CASP1 NFKB1	down	*
MUELLER_PLURINET	0.0000000	0.0000018	0.7195128	0.3986121	1.886506	270	TRIP13 DDX11 BIK RUVBL1 CDC45 MCM10 CHEK2 BUB1B COIL CCNB1 POLQ MPP6 PHGDH TRAIP GMPS DNMT3B AURKB TPX2 CCNB2 MCM4 MCM2 MYBL2 GRB7 ORC1 CDT1 LSM5 NME1 HMMR EXO1 NUDT1 NLE1 SMARCC1 CHAF1A AURKA POLD2 RAD54L PASK MCM3 CDC25C AIMP2 CHEK1 ORC6 FBL DCTPP1 DSCC1 GEMIN7 BLM PHB MNAT1 PARP1 CASP6 CKS1B PAK1 CDK1 SIGLEC12 BIRC5 ATIC GMNN GOT2 UNG FEN1 POLR1C SPAG5 MRPS12 SNRPE RECQL4 PA2G4 KPNB1 PELP1 CCNE1 SNRPA RAD9A SALL4 TK1 MYBBP1A HDAC1 NOC2L ANAPC1 POLD1 COPS6 ELAC2 CDC7 RMND5B GEMIN6 ERBB3 HMGA1 POP7 FAM136A RPA1 MCM6 MCM5 SNRPD1 LSM7 SRSF1 AATF LSM4 WDYHV1 TCERG1 PRMT5 STRBP NME1-NME2 MSH2 CCNA2 RFC5 WDR77 RAD51 SUPT3H TARBP2 CENPE MTHFD1 TP53 SEPHS1 APEX1 SNRPC PNN	up	***
REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY	0.0006629	0.0079907	0.4772708	0.7870575	1.886336	9	COL17A1 KRT5 LAMC2 ITGB4	up	**
REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES	0.0006180	0.0075820	0.4772708	0.5651110	1.884974	31	BRCA1 RBBP8 XRCC2 EXO1 EME1 EME2 RAD51AP1 BRIP1 BLM DNA2 RAD51D SLX4 RAD50 PALB2 RTEL1 RAD51 MUS81 SPIDR TOP3A RMI1 RMI2 RAD51B BARD1	up	**
SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN	0.0000983	0.0016199	0.5384341	0.4794885	1.884950	69	CCNO BIK DEPTOR GALNT6 DNAJC12 TOX3 CLGN TSFM SPDEF TFF3 SLC27A2 AGR2 CA12 ASTN2 SLC4A8 TJP3 MCCC2 SIDT1 IKBKB TTC9	up	**
WANG_ESOPHAGUS_CANCER_PROGRESSION_UP	0.0044454	0.0372995	0.4070179	-0.7362882	-1.883214	8	CXCL3 MYADM HSPE1 SRGN PLAUR	down	*
ZHENG_GLIOBLASTOMA_PLASTICITY_UP	0.0000003	0.0000107	0.6749629	0.4096781	1.883016	211	HELLS CPLX2 CDC45 CP NUP107 UGT8 CCNB1 UBE2T NDC80 SDK2 RACGAP1 ALDH1L1 ANLN BCAS1 POLE SPP1 ASPM PLK1 NUF2 CDCA8 AURKB ECT2 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 MCM2 PRC1 DPYSL4 CCNF CDT1 MELK EXO1 KIF23 BUB1 TOP2A AURKA CLSPN RRM2 GCAT RAD54L MCM3 LMNB1 RBP1 LIG1 CD24 ASS1 MAD2L1 PFKP RAD51AP1 SPRY1 INCENP CKS1B NUSAP1 APLP1 BIRC5 TESC TRIM2 FEN1 SPAG5 SEMA3A CRLF1 CTSV ATP9A KIF22 EPHB2 TK1 CENPQ	up	***
REACTOME_DNA_REPAIR	0.0000001	0.0000026	0.7049757	0.3986418	1.880366	260	EYA1 RUVBL1 FANCI CHEK2 EYA2 TIMELESS POLQ UBE2T BRCA1 POLE RBBP8 PMS2 XRCC2 DTL LIG3 SMUG1 EXO1 TP53BP1 POLM RHNO1 FANCA EME1 ATR POLD2 ASCC2 CLSPN PRKDC FANCD2 LIG1 EME2 TOPBP1 CHEK1 ACTL6A RAD51AP1 XRCC1 BRIP1 RAD18 BLM PPP5C ERCC2 MNAT1 PARP1 POLN POLE2 UNG DNA2 NEIL3 FEN1 MAD2L2 PIAS3 POLR2H FANCG DCLRE1C FANCF POLL MBD4 RAD9A RAD51D COPS7B MGMT TCEA1 USP43 POLD1 POLB COPS6 SLX4 RAD50 PALB2 ASCC1 RPA1 POLR2J FANCM UBE2V2 KDM4B XRCC4 TDP1 UIMC1 POLR2I MCRS1 MSH2 CCNA2 NFRKB RTEL1 RFC5 INO80E RAD51 EYA4 PAXIP1 SIRT6 PNKP PARG XPC MPG TP53 NEIL1 APEX1 RAD1 DDB2 PIAS4 ACTR5 ERCC3 ALKBH2 PARP2 INO80B MUS81 SPIDR TOP3A PRPF19 ATRIP RNF8 DCLRE1B MSH6 DCLRE1A ASCC3 POT1 HERC2 RMI1 XRCC5 TIPIN UVSSA PPP4C UBE2L6 POLD3 COPS7A RBX1 XRCC6 RMI2 MSH3	up	***
LIAO_METASTASIS	0.0000000	0.0000000	0.8513391	0.3796170	1.880027	462	DKK1 TRIP13 HKDC1 PTGES FOXM1 SLC29A4 HJURP BUB1B SLFN13 HOXD8 SULT1C2 UCHL1 IGF2BP3 CIB2 KIF18B TSHZ2 GCNT3 SLC2A1 TOX3 DDIT4 THEM4 CDCA7 ZP3 GTSE1 NPAS2 BAMBI NUF2 ALDH18A1 ECT2 SOX9 RAD54B MYBL2 CA12 FERMT1 HPS3 SPINK1 TMCC1 NUB1 PPP1R9A TTLL4 RUVBL2 ITGA2 KCNH2 IGF2BP2 PAFAH1B3 VANGL1 MPHOSPH9 ANKRD52 RAD54L PKM FHOD3 SOX4 BRD9 PLXNA1 MORC2 PDZK1IP1 ZNF618 SPINT1 SCAMP5 CCL28 GNPDA1 PTGFRN SNAPC4 NOL3 ALDOA DLG5 DHRS13 PES1 GPX8 PPIL2 CBX5 DMKN BCAS4 BIRC5 WDR54 ATIC E2F1 FBXO41 KIF2A NEIL3 ZNF789 PDK1 EZH2 USP42 SLC44A3 TRAF5 IGSF3 ZNF827 DENND1A SUSD4 ITPR3 TPD52L2 WFIKKN1 GRAMD1A CCNE1 ST14 DPP3 COL1A1 COL1A2 SMG5 TACC3 EFCAB2 SNRPA TUBB2A MAPK13 TMEM237 ZNF234 DTYMK DBN1 ENAH CHTF18 ZNF239 SCN8A HDAC1 MSI2 PKP4 ASNS CDK13 FXYD3 CLTB CDC7 SH2B1 TSTA3 UBE2O CENPM PLD1 TWIST1 ZCCHC17 HMGA1 ASRGL1 ZNF432 GNG4 SURF2 ZNF783 TMCO4 MYEF2 PFKFB4 PDIA4 RHOBTB1 STK39 ZNF765 SF3A2 ATAD2 ARFGAP1 STRBP SPAG4 CKAP4 INTS8 SPON2 LRP11 PRR11 DENR CEP164 PCSK5 PRPF31 CAPN10 ZNF292 SLC25A29 MROH1 ZMYND19 GBP2 IKZF4 TMED9 LLGL1 UBAP2L PNKP TCF3 DTNBP1 FBLIM1 ROBO1 DNAJC10 KIAA1522 SLC36A1 ANKRD46 RASA4 DNM1L RABL6 TMEM201	up	***
DER_IFN_GAMMA_RESPONSE_DN	0.0025963	0.0245027	0.4317077	-0.6866531	-1.879003	10	INPP5A IDI1 PTX3 TRAF6	down	*
GERY_CEBP_TARGETS	0.0000211	0.0004259	0.5756103	-0.3837413	-1.876651	108	EREG HMOX1 ABHD5 PPARG MNDA GREM2 LPL BAIAP2 GPCPD1 HMGCR IER2 HBEGF BTG2 PTX3 SERPINB9 TFRC KLF4 PLAUR ID3 PER2 CXCL2 ATF3 ID2 DUSP1 NUS1 HGSNAT PROCR TCTE3 CYB5R1 HSPA1B JUNB PPP1R15A IFRD1 ACSL1 FOS CHORDC1 PEA15 CD1D PIM1 RGS2	down	***
KEGG_LYSOSOME	0.0000214	0.0004271	0.5756103	-0.3809525	-1.874906	109	ACP5 MCOLN1 LIPA CTSW MANBA GNPTAB FUCA1 LAMP1 SLC11A1 GGA2 MAN2B1 ARSB ASAH1 GM2A CLN5 ATP6V1H PPT1 GAA TPP1 CTSD LAPTM5 ATP6V0D2 M6PR GLB1 HEXB HGSNAT CTSS CTSZ ATP6V0B DNASE2 IDS ENTPD4 AP3B1 CLN3 ATP6V0D1 CD164 SORT1 AP1G1 GALC ATP6V0C	down	***
BIOCARTA_NKT_PATHWAY	0.0027799	0.0255797	0.4317077	-0.5444715	-1.873115	22	IL18R1 CCL3 CCL4 TGFB2 IFNGR1 CCR7 CCR4 TGFB1 CCR1 CXCR4 CSF2 IL5 CD4 CCR5 IFNG	down	*
REACTOME_CILIUM_ASSEMBLY	0.0000010	0.0000270	0.6435518	0.4165135	1.871471	177	CEP72 CEP89 RPGRIP1L NEK2 RAB3IP MKS1 TUBB2B IFT122 TTC26 CEP70 PLK1 IFT27 EXOC3 CCT2 DCTN2 HAUS5 CEP250 BBS1 KIF3B FBF1 EXOC4 CCT5 ODF2 SFI1 IFT43 WDR60 IFT172 KIF3C CNGB1 C2CD3 IQCB1 CDK1 CEP97 CENPJ CCT3 TCTN2 DYNLL2 SMO FGFR1OP IFT52 CEP63 BBS5 CEP192 NPHP1 EXOC7 TUBG1 NINL TUBB2A TUBA3D TUBA8 CNGA4 TRAF3IP1 CKAP5 WDR34 GBF1 TCTN1 CDK5RAP2 WDR35 HAUS6 DYNC2H1 HAUS4 UNC119B CEP152 B9D1 ALMS1 CEP164 CLUAP1 TUBA4B MARK4 TCTEX1D1 TTC30B TUBA1C CLASP1 KIF24 CEP290 DYNC1H1 PLK4 AKAP9 PCNT RAB11FIP3 KIFAP3	up	***
SEKI_INFLAMMATORY_RESPONSE_LPS_UP	0.0003800	0.0051932	0.4984931	-0.4133773	-1.871162	70	CXCL3 EREG ZMYND15 CXCL16 PTPRE BMP2 EGR2 CD44 CCRL2 FOSL1 SLC15A3 STX11 ABCB1 BIRC2 CCL3 MAFF BTG1 REL GSAP SOD2 ICAM1 RIPK2 RND1 NFKBIA ADAMTS7 JDP2 EGR1	down	**
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP	0.0000001	0.0000034	0.7049757	0.3939851	1.870938	281	SLCO5A1 HELLS PARPBP FANCI BUB1B ZNF84 CENPF FLVCR1 PBK KIF18B COL27A1 TTF2 NDC80 DEPDC1B CDCA7 TTK GINS1 C6orf141 RACGAP1 ANLN NUF2 ECT2 SFXN1 E2F3 FIGNL1 ANKRD22 RBBP8 FCGR3B UHRF1 MCM4 TYMS FERMT1 PRC1 CCNF DTL CCT6A MCM8 ZWINT CXCL10 MELK KIF23 CEP55 KIF15 TOP2A DPY19L1 CBX3 VASH2 MPHOSPH9 RRM2 PRKDC WDHD1 HOXC6 KIF11 SOX4 CHEK1 DNAJC9 MAD2L1 RAD51AP1 DSCC1 BRIP1 CXCL9 CXCL11 NUSAP1 CDK1 POLE2 CENPJ ZNF260 GMNN UNG NCAPG VANGL2 DNA2 COL3A1 SSX2IP EZH2 DIAPH3 ARNT2 COL1A1 COL1A2 DLGAP5	up	***
PID_FANCONI_PATHWAY	0.0005365	0.0068243	0.4772708	0.5322395	1.870640	40	FANCI UBE2T BRCA1 FANCA ATR SSPO FANCD2 TOPBP1 CHEK1 BRIP1 BLM FANCG FANCF RAD9A RAD50 PALB2 RPA1 FANCM RFC5 FBXW11 RAD1 TOP3A ATRIP RMI1	up	**
YU_MYC_TARGETS_DN	0.0008140	0.0095420	0.4772708	-0.4493123	-1.869168	47	ACP5 MNDA GGA2 LIFR MS4A1 CD37 RBMS1 PTPRC HLA-DQA1 BTG1 KLF2 CD74 CD1D MACF1 SPIB CTSH MAP4K2 IL10RA PLD4 ARID3B UNC93B1 PYGM BLK	down	**
WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN	0.0000016	0.0000421	0.6435518	-0.3536977	-1.868167	173	MNDA CAV1 PRKAR1A RCHY1 TMX4 ATP2B1 WNT2B MAP3K8 CSGALNACT2 SIRPA ZYG11B KPNA5 PTPN12 PTPN21 BNIP2 PPM1K CPVL RUNX1T1 PLEKHM3 DAB2 SOCS5 FBXL3 SPAG9 RBMS1 UBE2E2 WASF3 GCA DSE CLIP4 CALM2 TGFB2 PROCR ZNF330 SH3BP5 GABPA CCDC50 OSTM1 FERMT2 DDX5 TSPYL1 EPC2 RNF146 CELF2 BLOC1S6 PKD2 FLNC HNRNPD TCF4 PLSCR4 SOD2 SBSPON SPOCK2 KAT2B EPB41L5 TIAM1 POLR2M TTC28 TIMP3 MAGI2-AS3 KIF1B FAM13B ZFPM2 WDFY3 REEP1 PSIP1 CDON CFL2 MYH10 CBR4 PTGS1	down	***
WAGNER_APO2_SENSITIVITY	0.0011986	0.0130262	0.4550599	0.6017161	1.867762	22	FUT6 GALNT14 GALNT6 FUT3 GALNT10 GALNT9 FUT2 POFUT1 GALNT3	up	*
REACTOME_RESOLUTION_OF_ABASIC_SITES_AP_SITES	0.0009263	0.0106763	0.4772708	0.5395638	1.866263	37	POLE LIG3 SMUG1 POLD2 LIG1 XRCC1 PARP1 POLE2 UNG FEN1 MBD4 POLD1 POLB RPA1 RFC5 PNKP PARG MPG NEIL1 APEX1 PARP2 POLD3 RFC3 POLE4 RFC4 PCNA ADPRHL2 TDG NEIL2 RPA3 POLE3 MUTYH	up	*
BURTON_ADIPOGENESIS_PEAK_AT_16HR	0.0007245	0.0086394	0.4772708	0.5433048	1.866187	36	HELLS CDCA7 CDC6 MCM4 POLA2 MCM7 RRM2 SERPINA3 MCM3 CHAF1B ASS1 ASF1B FEN1 DNMT1 POLD1 HMGA1 MCM6 MCM5 ABCF2 RAD51 SMC2	up	**
BAELDE_DIABETIC_NEPHROPATHY_UP	0.0004408	0.0058224	0.4984931	-0.4119479	-1.864691	70	SEMA6A ACVRL1 TEK PECAM1 CLEC3B FBP1 TIE1 RAMP2 PTPRB ENG ARHGEF15 INPP5K EML1 FXYD2 GAS6 SLCO2A1 PDE2A PTPRM ZCCHC24 CCL3 PTGIS ADAMTSL2 VAT1 GAS2L1 PPM1F CD34 ICAM2	down	**
LANDIS_ERBB2_BREAST_TUMORS_324_DN	0.0000200	0.0004055	0.5756103	-0.3665658	-1.864529	132	ABHD5 SOWAHC CLEC3B CYP4B1 THBD PTPRB LYL1 ST3GAL6 QKI ALAS1 GAS6 CD36 RRAGC CYB5A FZD4 SPTBN1 CES1 ZEB1 AHNAK SCP2 SORBS1 BNIP2 KLF4 PDE8A NKIRAS1 ADIPOR2 PPP2R5A HLA-DQA1 VWF SNRK CD34 ACSL1 CD151 CHPT1 TSC22D1 GNAI1 CPT2 APLP2 DECR1 MFNG	down	***
GRADE_COLON_AND_RECTAL_CANCER_UP	0.0000002	0.0000057	0.6901325	0.3964051	1.862101	247	HELLS HJURP CDC45 ZMYND8 PDCD6 ZNF84 CCNB1 TIMELESS POLQ PDCD2L THOC3 DDIT4 CDCA7 HILPDA SPP1 PLK1 CDC6 SOX9 MCM4 MCM2 FERMT1 EIF3B LDHB MELK KIF23 KNTC1 PAFAH1B3 EEF1E1 CCT5 DPY19L1 BPHL AURKA POLD2 MCM7 ICA1 RRM2 PRKDC MRPL3 PKM GPSM2 MCM3 AHCY PSMD4 FBL BACE2 PERP HOXB5 NUSAP1 URI1 CDK1 DNTTIP1 ATIC TRAP1 DGAT2 MRPL17 METTL3 TRAF5 LAPTM4B PA2G4 EIF6 EFTUD2 CHCHD2 VBP1 ACBD6 INTS7 POFUT1 MRGBP DNAJA3 EPHB2 SSRP1 DAP3 AAMP CCT7 ETV4 GEMIN6 PSMB3 METTL2B DHX8 NOB1 MCM5 SRSF1 RTKN RCC1 GTPBP10 GLO1 RFC5 CARHSP1 MRPL9 SLC12A2 SMPD4 ALG1 MTHFD1 SEPHS1 PPIA CDC25B SH3GL1 TRUB2 AZGP1 TFB1M CSTF1	up	***
SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_UP	0.0016739	0.0172431	0.4550599	0.5624585	1.861137	29	IGHV4-61 KCNK5 MCM10 CP CENPF KRT16 LDHB TTLL4 TRIM29 EGFR CXCL9 TNFRSF21 CDH3 CHST3 MMP7 MCM5 SCRG1 RARRES1	up	*
BIOCARTA_IL1R_PATHWAY	0.0035163	0.0309628	0.4317077	-0.5063501	-1.860077	27	IL1A IL1B MYD88 IL1RN TRAF6 MAP2K3 NFKB1 IRAK2 TGFB2 IL6 JUN MAPK8 TGFB1	down	*
BENPORATH_CYCLING_GENES	0.0000000	0.0000000	0.8986712	0.3726025	1.860057	569	MNX1 TRIP13 DDX11 FOXM1 ABCC2 HELLS MDM1 HJURP CDC45 FANCI TROAP TFAP2A CHEK2 BUB1B NEK2 CCNB1 CENPF POLQ UBE2T MND1 PBK TTF2 NDC80 PRIM2 PIF1 BRCA1 TFF3 DEPDC1B CDCA7 TTK E2F8 GTSE1 KIF14 ANLN CCDC14 TRAIP STIL COL7A1 FLAD1 TOMM34 CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 RBBP8 UHRF1 MCM4 MCM2 TYMS CDC25A PRC1 ORC1 CCNF DTL MCM8 ASPHD2 MAP2K6 RCCD1 NCAPD2 ZWINT SPDL1 TRIM45 HAUS5 WDR62 MELK HMMR EXO1 KIF23 CEP55 STAG3 CHAF1A MKI67 RHNO1 BUB1 FANCA TOP2A IDO1 CENPL AURKA CBX3 VANGL1 ODF2 TMEM132A KIF2C C6 POC1A CLSPN RRM2 RHOBTB3 RAD54L KIF11 PASK FANCD2 GPSM2 CHAF1B HORMAD1 LMNB1 CDC25C CD24 CDC42EP1 TOPBP1 MAD2L1 RAD51AP1 MDM2 TRMT2A DSCC1 CAPS PKMYT1 RAD18 ZNF587 DET1 KNSTRN CKS1B CDKN2C CXCL14 HPS4 NUSAP1 ASF1B RNPC3 BIRC5 AP3D1 GMNN GOLGA8A E2F1 UNG DNA2 MRPS2 LARP1 NEIL3 FEN1 PSMG3 SPAG5 TNPO2 FADD VPS72 RECQL4 SRD5A1 ITPR3 KPNB1 RANGAP1 FANCG INTS7 ILF2 CCNE1 DLGAP5 TACC3 MBD4 TUBB2A KIF22 MAPK13 USB1 CENPQ GINS2 FZR1 ANP32E KIF20B ENOSF1 SAP30 CDC7 CKAP5 BRD8 VPS25 CDC20 CENPM EFHC1 AP3M2 CDR2 ABCA7 MCM6 CKAP2 DHX8 MCM5 LRRC17	up	***
PID_PDGFRA_PATHWAY	0.0046697	0.0385981	0.4070179	-0.5513279	-1.859823	20	CAV1 CRK SRF JUN JAK1 RAPGEF1 PIK3R1 GRB2 FOS	down	*
MARSON_FOXP3_TARGETS_STIMULATED_DN	0.0051387	0.0416602	0.4070179	-0.7268298	-1.859022	8	CPEB2 PPP1R13B FOXO3 TEC DNAJB4	down	*
TURJANSKI_MAPK7_TARGETS	0.0054122	0.0430747	0.4070179	-0.7715090	-1.858778	7	FOSL1 MEF2A ETS1 FOS	down	*
LIAN_LIPA_TARGETS_6M	0.0004365	0.0057924	0.4984931	-0.4290351	-1.858321	61	CXCL3 ACP5 HMOX1 MS4A7 FCN1 SLC15A3 MARCO SLC11A1 IGSF6 LILRB3 PLA2G7 MSR1 MPEG1 MYRIP ATP6V0D2 FCER1G MMP19 KLRB1 UTRN C1QA CSTA	down	**
REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	0.0001381	0.0021482	0.5188481	0.4592804	1.858070	79	SAA1 HP IGLV3-27 IGKV1-17 HBA1 HBA2 IGKV3-15 IGKV3-11 IGKV1-16 STAB2 IGKV4-1 HBB IGKV2D-28 APOL1 IGLV1-44 HPR IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 COL3A1 IGLV7-43 COL1A1 COL1A2 IGLV6-57 COLEC11 IGLV1-47	up	**
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP	0.0002167	0.0031583	0.5188481	-0.4049470	-1.856368	76	CD52 FCN1 LY86 CD8A ENTPD1 IFI30 LCP1 APOC1 FABP5 CFD LAPTM5 RBMS1 PTPRC CD53 FCER1G CD48 RAB31 RAC2 TYROBP CSTA GLIPR1 GMFG RASSF2 CELF2 CXCR4 IFFO1 S100A4 GLUL CCND3 C1QB AOAH S100A8	down	**
BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP	0.0003059	0.0042981	0.4984931	0.5195398	1.855993	43	KIF20A CPSF6 GINS1 CCNB2 CPD PRKDC CD24 PON2 CCT3 PEG10 SNRPE CBX1 DUSP12 ENAH VIL1 ACLY SNRPD1 NT5DC2 ATAD2 CKAP4 MRPL9 UBAP2L	up	**
FARDIN_HYPOXIA_9	0.0009433	0.0108501	0.4772708	0.8325958	1.854632	7	AK4 DDIT4 ALDOC FAM162A PDK1	up	*
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN	0.0000000	0.0000013	0.7195128	0.3864479	1.853682	302	TRIP13 HELLS RUVBL1 CDC45 TICRR MCM10 GPT2 BUB1B UBE2T MPP6 PBK SLC2A1 TSFM BRCA1 GINS1 E2F8 SLC27A2 NUF2 PTTG1 CDC6 SFXN1 TFDP2 UHRF1 KNOP1 MCM4 MCM2 TYMS CDC25A UMPS MYBL2 XRCC2 DTL ACY1 TDRKH MCM8 GINS4 ZWINT RANBP1 MELK EXO1 KIF23 KCNN4 CHAF1A BUB1 PUS7 MCM7 E2F2 CLSPN RRM2 RAD54L SYT2 MCM3 CHAF1B PLXNA1 SLC9A3R1 ORC6 ACTL6A MAD2L1 PFKP RAD51AP1 DCTPP1 PIH1D1 SPC24 DSCC1 PKMYT1 BRIP1 BLM FADS2 GEMIN4 KNSTRN CKS1B ASF1B POLE2 RFWD3 SIGLEC12 CENPH CCM2 GMNN UNG NCAPG MCAT TCTN2 PSAT1 PDK1 FEN1 MRPS12 MTBP DIAPH3 HSPA4L CCNE1 KIF22 DPH2 TK1 DBN1 ESCO2 GINS2 ETV4 CENPK KLHDC3 CENPV DCUN1D5 CENPM FAM136A NOL6 MCM6 KIF21B MCM5 GINS3 EXOSC5 GGT5 ATAD2 TSR1 MSH2 CCNA2 SLC2A5	up	***
MARSON_FOXP3_TARGETS_UP	0.0004780	0.0062391	0.4984931	-0.4276174	-1.852180	61	SWAP70 PDLIM2 LRRC8C CD44 SAMHD1 MALAT1 GM2A CYB5A MCL1 VIM ARHGAP9 MAPRE2 MYO1C ETS1 RAC2 OSBPL9 IRF8 MBNL2 CELF2 NKG7 CD81 SERINC3 TIAM1 S100A4	down	**
JAEGER_METASTASIS_DN	0.0000013	0.0000343	0.6435518	0.4038346	1.851068	200	COL17A1 LTF ALDH3B2 GPR87 PTPRZ1 TP63 BBOX1 KRT5 LAD1 FAT2 S100A2 PKP1 SLC2A1 ABCA12 COL7A1 KRT16 AKR1C1 DIO2 PAK6 SPINT2 LSR CA12 FERMT1 KRT15 AP1G2 GPX2 MAP7 LAMC2 F2RL1 STAP2 TRIM29 ITGB4 FLG TMEM45A FHOD3 EGFR CD24 PDZK1IP1 ASS1 MST1R PERP EHF GRHL2 LTB4R CXCL14 RAPGEFL1 GJB3 CDH3 SRD5A1 ITPR3 IRF6 NET1 LGR5 ST14 ARHGAP32 PKP3 MAPK13 S100A9 KRT19 ELMO3 FXYD3 ENPP2 CLTB	up	***
REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS	0.0005992	0.0074009	0.4772708	0.4911945	1.849768	56	TIMELESS BRCA1 RBBP8 EXO1 TP53BP1 RHNO1 ATR CLSPN TOPBP1 CHEK1 BRIP1 BLM DNA2 RAD9A RAD50 RPA1 UBE2V2 UIMC1 CCNA2 RFC5 SIRT6 RAD1 PIAS4 TOP3A ATRIP RNF8 HERC2 RMI1 TIPIN PPP4C RMI2 RFC3 BARD1 RFC4	up	**
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN	0.0011368	0.0126024	0.4550599	-0.4691373	-1.847841	38	IL1B MIR22HG MKNK1 ANXA5 ITSN2 FLI1 PTPN12 HAUS2 LY96 CD53 BCLAF1 DDX5 USP7 CDC42EP3 EID1 ARFGAP3	down	*
BIOCARTA_IL2_PATHWAY	0.0053407	0.0429029	0.4070179	-0.5590716	-1.847704	19	STAT5A IL2RB JUN JAK1 GRB2 FOS MAPK8	down	*
HAHTOLA_SEZARY_SYNDROM_DN	0.0024401	0.0234292	0.4317077	-0.4716676	-1.844571	36	CTSW SERPINB9 HOPX CCL4 KLRD1 MATK CD160 KLRB1 IL2RB IRF8 NKG7 VAV3 SESN1 IL18RAP PTCH1 KLRF1 ZBTB16 GZMB DUSP2 KLRC1 GZMK	down	*
HOLLEMAN_PREDNISOLONE_RESISTANCE_ALL_DN	0.0037910	0.0326708	0.4317077	-0.6739180	-1.844154	10	SLC11A1 STOM MATK CST7 ARPC2 DAPK1 PIEZO1 MATN1	down	*
SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN	0.0008757	0.0101610	0.4772708	0.7945117	1.843524	8	PCSK6 DNAJC12 STC2 RND2 ARNT2	up	*
HOLLERN_PAPILLARY_BREAST_TUMOR	0.0046729	0.0385981	0.4070179	0.6553191	1.842898	15	BBOX1 HP UGT8 RHOV CEL WNT5B KRT19	up	*
PID_TCR_CALCIUM_PATHWAY	0.0045403	0.0379226	0.4070179	-0.5246059	-1.842379	24	AKAP5 FOSL1 NFATC3 PPP3CA JUN JUNB RCAN1 PRKACA FOS PPP3R1 FKBP1A CSF2 CHP1	down	*
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_GREY_UP	0.0049591	0.0403820	0.4070179	-0.5655844	-1.841452	18	ARRDC4 TFEC ADAMTS9 IRAK2 LBH CREBRF WHAMMP3 DUSP5 CCDC68 RORA	down	*
LE_EGR2_TARGETS_DN	0.0000597	0.0010436	0.5573322	-0.3875746	-1.840914	93	PRX CD55 CPEB2 CAT EMP2 LPL IDI1 HMGCR MAL CD9 ABCB1 SEMA3B RGCC MAPK8IP1 TIPARP CLDN5 MYO1B CDKN1A RAP1GDS1 MYH11 CMTM6 UTRN PIK3R1 MBP MSMO1 PEA15 GNAI1 ADAM10 SCN7A RTN1 LIMCH1 FDFT1 IL16 RNF13 PIM3 ZBTB16 TMEM30A HMGCS1 NR4A2	down	**
TERAMOTO_OPN_TARGETS_CLUSTER_7	0.0026050	0.0245433	0.4317077	0.6401579	1.839004	17	GPT2 TFAP2A PSPH PHGDH SPP1	up	*
REACTOME_TELOMERE_C_STRAND_LAGGING_STRAND_SYNTHESIS	0.0027710	0.0255527	0.4317077	0.5781372	1.838745	24	PRIM2 POLA2 POLD2 LIG1 DSCC1 BLM DNA2 FEN1 CHTF18 POLD1 RPA1 CHTF8 PRIM1 RFC5 CTC1 POLD3 RFC3 RFC4 PCNA WRN	up	*
BIOCARTA_RANMS_PATHWAY	0.0014076	0.0149446	0.4550599	0.7669993	1.838263	9	TPX2 RANBP1 KIF15 AURKA KPNB1 RANGAP1 RCC1	up	*
STANHILL_HRAS_TRANSFROMATION_UP	0.0016283	0.0168661	0.4550599	-0.8567511	-1.838185	5	HMOX1 HSPB1 DUSP1 JUN FOS	down	*
KAUFFMANN_DNA_REPLICATION_GENES	0.0000256	0.0005022	0.5756103	0.4238916	1.838035	127	CDC45 CENPF POLQ PRIM2 BRCA1 PTTG1 CDC6 MCM4 MCM2 ORC1 MCM8 LIG3 CHAF1A POLM POLA2 POLD2 MCM7 RRM2 MCM3 CHAF1B LIG1 TOPBP1 ORC6 REPIN1 BLM POLN SUPT5H SSBP1 POLE2 GMNN FEN1 EGF TEP1 POLL RAD9A CHTF18 MYBBP1A GINS2 POLD1 POLB NT5M CDC7 RPA1 MCM6 WRNIP1 MCM5 IGHMBP2 MSH2 RFC5 ABCF2 SMC2 PNKP CENPE	up	***
REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE	0.0001623	0.0024689	0.5188481	0.4492513	1.836887	87	CEP72 CEP89 RPGRIP1L NEK2 RAB3IP MKS1 CEP70 PLK1 DCTN2 HAUS5 CEP250 FBF1 ODF2 SFI1 C2CD3 IQCB1 CDK1 CEP97 CENPJ TCTN2 FGFR1OP CEP63 CEP192 NPHP1 TUBG1 NINL CKAP5 TCTN1 CDK5RAP2 HAUS6 HAUS4 CEP152 B9D1 ALMS1 CEP164 MARK4 CLASP1 KIF24 CEP290 DYNC1H1 PLK4 AKAP9 PCNT	up	**
BIOCARTA_PPARG_PATHWAY	0.0065275	0.0495710	0.4070179	-0.7179434	-1.836293	8	PPARG LPL NCOA1 RXRA CREBBP EP300	down	*
SANSOM_APC_TARGETS_UP	0.0000877	0.0014538	0.5384341	0.4293385	1.835076	113	HS3ST1 EPHB3 FOXA3 UBE2T TNNI1 CDCA7 TUBB2B ECT2 SOX9 MCM2 SP5 CA12 DTL REC8 MCM7 MAD1L1 MSX1 ABCC5 RNF43 PASK MCM3 SOX4 ANG MSI1 HES6 EHF SKP2 PARP1 URI1 KRT18 GNB1L UNG PSAT1 DIAPH3 GOLGA3 INTS7 ADAT1 TUBB2A EPHB2 DTYMK ZNF282 MARCKSL1	up	**
NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON	0.0014357	0.0151555	0.4550599	0.5474903	1.834743	32	DCST1 THEM4 THEM5 EFNA3 FLAD1 EFNA4 DCST2 TDRKH OAZ3 CKS1B ZBTB7B PYGO2 MRPL9 ADAM15 RORC MUC1 RUSC1 PMVK	up	*
REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	0.0001018	0.0016482	0.5384341	-0.4004400	-1.832945	79	RAMP3 GPR15 LHCGR ADCY9 ADCY4 RAMP2 CALCRL ADCYAP1R1 PRKAR1A RXFP1 GNGT2 ADRB1 GNG7 ADRB2 GPBAR1 PTGIR GNAI2 PTH1R ADCY2 IL6 PTGER4 CREB1 PTGER2 PRKACA GNAI1 GNG5 GPR84 GNB4	down	**
BERENJENO_TRANSFORMED_BY_RHOA_UP	0.0000000	0.0000000	0.8266573	0.3689256	1.830597	484	HMGA2 TRIP13 FOXM1 HELLS KIF20A AK4 CDC45 MCM10 NGEF NUP107 NEK2 CCNB1 TIMELESS UBE2T GGCT SLC2A1 PRIM2 BRCA1 CDCA7 TTK RACGAP1 IQGAP3 E2F8 GTSE1 ANLN IGFBP6 SPP1 ASPM CDCA8 AURKB CENPA PTTG1 ECT2 CDC6 GAPDH FIGNL1 UHRF1 MCM4 MCM2 TYMS SLC4A4 MYBL2 PRC1 ORC1 CCNF EIF3B DTL CIB1 SPDL1 TNC TAMM41 NME1 RANBP1 RUVBL2 TNNT2 DNPH1 EXO1 CISD1 KIF23 LAMC2 MKI67 BUB1 TOP2A AURKA POLA2 SAE1 KIF2C MCM7 CDCA5 WDHD1 NSUN2 TOM1L1 KIF11 MCM3 CHAF1B CDC25C AIMP2 EMG1 FAM162A LIG1 TOPBP1 CHEK1 DNAJC9 ORC6 ACTL6A MAD2L1 AHCY FBL RAD51AP1 DCTPP1 MDM2 FLNB INCENP PON2 CKS1B NUSAP1 CBX5 ASF1B CDK1 POLE2 UCK2 BIRC5 CCT3 TNK2 GMNN POLR3K E2F1 PSMB5 DNA2 BPGM PSAT1 FEN1 EZH2 RAET1E CBX1 NOP2 DIAPH3 PA2G4 RNASEH2A KPNB1 EIF6 RANGAP1 HSPA4L NET1 DNMT1 TUBG1 DLGAP5 ADAM12 TACC3 KIF22 SSRP1 TK1 DTYMK PKP4 SAP30 POLD1 NUP85 TYRO3 HLA-A CCT7 CDC7 CENPV PSMB3 CDC20 RPRD1B LRRC59 FAM136A RPA1 CDR2 CKAP2 MCM5 ANKRD1 SNRPD1 HAUS6 SRSF1 DNAJC21 RCC1 CCNG1 PHC2 LSM4 TSR1 TCERG1 NUP62 MSH2 CCNA2 ADM PRIM1 BANF1 SNRPD2 MRPS25 RFC5 ABCF2 HK2 RAD51 TPGS2	up	***
REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX	0.0016822	0.0172947	0.4550599	0.7296964	1.830358	11	CDC6 E2F3 ORC1 MCM8 E2F2 ORC6 E2F1	up	*
REACTOME_MITOCHONDRIAL_TRANSLATION	0.0001242	0.0019596	0.5188481	0.4424622	1.828765	90	TSFM MRPL46 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 MRPS30 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 GADD45GIP1 MTIF3 MRPL9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 MRPS16 MRPL12 MRPL43 MRPL2 MRPS6 MRPS7 MRPL35 MRPL13 MRPL33 MT-RNR1 MRPL19 MRPS15 MRPS10 MRPL38 MTRF1L MT-RNR2 MRPL10 MRPL23	up	**
MA_MYELOID_DIFFERENTIATION_DN	0.0018139	0.0183301	0.4550599	-0.4718461	-1.827353	35	PDE1B CITED2 NFATC3 PLA2G7 HBEGF CES1 ZFAND5 RBPJ YBX1 STAT4 NOTCH1 FOS GNA13 HSPA2 KIF1B SMAD4	down	*
LI_AMPLIFIED_IN_LUNG_CANCER	0.0000074	0.0001625	0.6105269	0.4116738	1.825546	155	LTF TSPAN8 KRT5 PDCD6 UCHL1 TFF3 LCN2 SPP1 GPI AKR1C1 SPINT2 SPINK1 NME1 LDHB SDHA CCT5 CBX3 FGG ZNF146 PKM SOX4 PFN2 MDK SPINT1 PFKP IDH2 ALDOA CLDN9 HDGF CCT3 GIPR TRIM2 SNRPE DAP LAPTM4B COL1A1 COL1A2 GALNS JTB ENC1 MARCKSL1 COL11A1 TSTA3 ERBB3 ABCC3 HAX1 PSMB4 CKAP4 CEACAM5 CDH1 SNRPD2 NME4 PTPRF ERBB2 UBE2C ENO1 MUC1	up	***
WANG_BARRETTS_ESOPHAGUS_DN	0.0060395	0.0467001	0.4070179	-0.5520358	-1.824450	19	LTA4H EMP2 NFE2L2 FMO2 ACTR3 STK24 PRCP AQP3 SERPINB1 CUL3 S100A8	down	*
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP	0.0001576	0.0024098	0.5188481	0.4311484	1.823357	103	FAM83B ENTPD2 KRT5 LAD1 EPN3 LCN2 PRR15L KRT16 SPINT2 KRT15 C6orf132 CBLC TRIM29 RNF43 SERPINA3 CD24 PDZK1IP1 PROM2 SPINT1 STEAP4 EHF GRHL2 DMKN EPHA1 ESRP1 GJB3 CDH3 MYO5B IRF6 ST14 PKP3 ELMO3 FXYD3 TMEM30B SSH3 RTKN OVOL2 TC2N PRSS8 CDH1 HOOK2 COX5B RHOD RAB25 KIAA1522 FGFBP1	up	**
BIOCARTA_FCER1_PATHWAY	0.0037251	0.0324393	0.4317077	-0.4638548	-1.820773	37	FCER1A NFATC3 PPP3CA PPP3CC FCER1G CALM2 JUN PIK3R1 GRB2 FOS CALM1 MAPK8 PAK2 MS4A2 MAPK1 PIK3CG MAP3K1	down	*
ZHAN_MULTIPLE_MYELOMA_PR_DN	0.0020985	0.0206156	0.4317077	-0.4405705	-1.820288	46	RGPD5 SLC7A7 NLK MOB3C PPM1K EPS15 TMEM167B TFEB DDHD2 BAZ2B KAT2B FGF2 PAXIP1-AS2 ARHGAP18 JMJD1C NR3C2 CBX7 SH3GLB1 CNTN1 ANKRD44 RASGRP3 PLCL1 GAB1 CYLD	down	*
NAKAMURA_LUNG_CANCER	0.0016139	0.0167489	0.4550599	0.8171525	1.820232	7	ATP10B TFPI2 SCG5 TOP2A AURKA COL11A1 MCM6	up	*
REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	0.0000570	0.0009982	0.5573322	0.4219898	1.819279	122	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 DYNC1I1 COPB2 KIF27 DCTN2 KIF23 BICD1 KIF15 COPG2 COPG1 PAFAH1B3 KIF3B KIF2C KIF11 KDELR2 KIF3C TMED3 NSF KIF5A STX18 KIF19 KIF2A DYNLL2 RAB6B TUBB2A TUBA3D KIF22 ARF5 TUBA8 KIF21A KIF20B KLC2 KLC4 KDELR3 GBF1 DYNC1LI2 KIF21B COPZ1 ARFGAP1 TUBA4B COPA TMED9 CENPE COPZ2 TUBA1C	up	***
DELPUECH_FOXO3_TARGETS_DN	0.0012508	0.0134613	0.4550599	0.5349021	1.818362	34	FOXM1 NEK2 CENPF PRC1 SHMT2 XPOT ZWINT MKI67 AURKA PFN2 NUSAP1 MB KIF22 DTYMK HAX1 PYCR1 APEX1 UBE2C	up	*
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN	0.0003185	0.0044188	0.4984931	-0.4039737	-1.818342	71	CXCL3 IL1B PTPRE CD44 FOSL1 IL1RN SLC11A1 TXNIP ITGA5 PDGFA RHOB PLAUR CCL3 NFKB1 DUSP1 SOCS3 RAC2 JUNB CD83 UBB BCL6B EHD1 TSC22D1 PIM1 ETS2 IL18RAP TRAF1 NFKBIA TNFSF9 HERPUD1 CSF2RB BCL10 CSF3 PTGS2 DUSP2 MT1X CDC42EP4	down	**
REACTOME_MITOTIC_SPINDLE_CHECKPOINT	0.0001227	0.0019407	0.5188481	0.4317526	1.816185	100	BUB1B NUP107 CENPF NDC80 PLK1 NUF2 CDCA8 AURKB CENPA DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 MAD2L1 CENPO SPC24 INCENP ANAPC5 CENPH BIRC5 KIF2A ANAPC7 DYNLL2 CENPP RANGAP1 CDC23 CENPQ ANAPC1 NUP85 CENPK CKAP5 CDC20 CENPM DYNC1LI2 CENPT ANAPC2 ZWILCH SEC13 CENPE UBE2C PPP2R5D CLASP1 DYNC1H1 DSN1 PPP2R5E NSL1 RCC2	up	**
SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN	0.0031652	0.0284608	0.4317077	0.6321047	1.815869	17	LTF CEACAM1 CP BAMBI SIX1 CXCL9 PSAT1 PEG10 CDH3 SRD5A1 S100A9	up	*
KEGG_TGF_BETA_SIGNALING_PATHWAY	0.0003742	0.0051266	0.4984931	-0.3961046	-1.815832	76	SMAD6 ACVRL1 BMP2 BMPR2 TGFBR2 RHOA ZFYVE16 NODAL ROCK2 ID3 ROCK1 THBS1 ID2 SMAD7 INHBA TGFB2 ID4 PPP2CA PPP2CB TGFB1 ZFYVE9 LTBP1 SMAD2 RBL2 CREBBP SMAD4 ACVR1C MAPK1 NOG EP300 GDF7 SKP1 BMPR1A	down	**
SHEPARD_CRUSH_AND_BURN_MUTANT_DN	0.0000441	0.0008009	0.5573322	0.4122234	1.815533	143	FOXM1 PARPBP BUB1B CCNB1 TOX3 PRIM2 PIF1 TTK CDCA2 RACGAP1 GTSE1 KIF14 ANLN ASPM AURKB ECT2 DIO2 TPX2 CCNB2 GOLGB1 PRC1 CEP250 MELK KIF23 CEP55 MKI67 AP4M1 LGMN MYO10 KIF2C KIF11 MDK SOX11 HES6 PON1 CDK1 BIRC5 NEIL3 ARNT2 DLGAP5 TACC3 LMNB2 HMGN3 TK1 TUBA8 CHD5 ARHGAP12 KDM3A CDC20 HMGA1	up	***
PID_BCR_5PATHWAY	0.0008847	0.0102400	0.4772708	-0.4248249	-1.815126	57	BCL2A1 CD22 PAG1 PPP3CA TRAF6 PPP3CC NFKB1 PTPRC JUN SH3BP5 ETS1 PIK3R1 GRB2 MALT1 PLCG2 FOS MAPK8 CD19 NFKBIA PTEN MAPK1 CD79B DAPP1 BCL10 MAP3K1	down	*
ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP	0.0054146	0.0430747	0.4070179	-0.4897922	-1.811842	28	CAT FUCA1 RB1 ATP6V1B2 CST3 KIAA0513 PRCP TIMP2 APLP2 FCGRT TIAM1 CXCR4 S100A4	down	*
VERHAAK_GLIOBLASTOMA_PRONEURAL	0.0000729	0.0012516	0.5384341	0.4202053	1.811260	123	SLCO5A1 MCM10 SOX2 SCN3A TOX3 CLGN SRGAP3 E2F3 ARHGAP33 CDC25A FERMT1 DPYSL4 TMCC1 EPHB1 MPPED2 PODXL2 WASF1 PAFAH1B3 MYO10 FHOD3 SOX4 PFN2 RNFT2 TOPBP1 SOX11 PPM1E RALGPS1 CBX1 MAST1 DBN1 SPTBN2 ATAD5 MARCKSL1 CDC7 ZFP69B ERBB3 NRXN2 ZNF248 KIF21B GNG4 MARCKS GADD45G ZNF286A MMP16 FLRT1 ICK	up	**
LU_AGING_BRAIN_UP	0.0000010	0.0000271	0.6435518	-0.3309742	-1.811009	230	PECAM1 GREB1 PTP4A2 RDX HSD17B6 GPC5 FYN CAV1 QKI S1PR1 MAL TGFBR2 ZEB2 TXNIP APOD SEMA3B RAPGEF4 CSRP1 PICALM ANXA5 LITAF ABCG1 RNASE1 CAV2 STOM TOR1AIP1 TMEM123 NFE2L2 SFRP1 CLK1 TIPARP LRP4 KDSR TLE4 AHNAK SCP2 ZCCHC24 ZNF423 CLDN5 EPM2A CLIC4 VIM CD302 PIK3C2A WFS1 TP53BP2 AFF1 ANXA3 VWF TOPORS KANK1 VAMP3 ID4 NEK7 SNAP23 VAT1 SLC14A1 FERMT2 PODXL FRYL RASSF2 ICAM2 MYL12A RIN2 PHF3 TGIF1 BAZ2B HNRNPH3 TOB1 LTBP1 CLEC2B RBL2 HSPA2 FGF2 PDLIM5 CEP170 NT5C2 CEBPD PIP4K2A PARVA METTL7A NFKBIA	down	***
DOANE_BREAST_CANCER_ESR1_DN	0.0017981	0.0182149	0.4550599	0.5403701	1.810882	32	BBOX1 KRT5 GABRP UGT8 IGF2BP3 MPP6 KRT16 TTLL4 EGFR ASS1 SOX11 GJB3 PSAT1 CHST3 MMP7 PGBD5	up	*
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP	0.0000014	0.0000374	0.6435518	-0.3327116	-1.809256	218	EPAS1 CXCL3 EREG IL1A OLR1 CD55 IL1B FYN NEDD4L FOSL1 MYD88 SLC39A8 S1PR1 ALAS1 BCL2A1 PPM1D IER2 RBM7 RRAGC EIF1 PTX3 ZMYM6 GRN ARHGEF2 FBXL5 EIF1B EVI2B YBX3 ACSL3 PLAUR VRK2 LY96 CTBS PNRC1 DUSP1 EVI2A ANXA3 HEXB PROCR IL6 CREM DCTN6 SOCS3 SNAP23 PIKFYVE JUNB IFNGR1 IFRD1 LYRM1 AGFG1 PELI1 KLF2 MME SERPINB1 TGIF1 VAMP4 SOD2 STON1 RGS2 CLEC2B PDE4B ETS2 TNFAIP8 EPN2 TAB2 RIPK2 EPHA2 MTUS1 CYTH1 DOCK4 EHD4 PMAIP1 IRF2 ARHGEF18 HTRA2	down	***
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	0.0000000	0.0000004	0.7614608	-0.3173123	-1.809133	345	CXCL3 SEMA6A EREG HSPB7 ARHGAP31 IL1A DENND5A CD55 ZC3H12C IL1B RAPGEF2 MIR22HG CD44 CCRL2 NEDD4L FOSL1 UBE2FP1 IL23A ZEB2 PDE2A KCNAB1 TMPRSS6 ATP2B1 CLCF1 SGMS2 ADAM17 LIFR PRMT5-AS1 MTF1 BTG2 EIF5 RNF144B LITAF KLF6 PTX3 EIF4E TNS1 ZFYVE16 TCF7L2 GPM6A PPP3CC AGBL1 IL10 MAP2K3 STAT5A TBC1D9 ITPRIP PLAUR PXDC1 TNFSF15 DRAM1 NFKB1 CXCL2 IRAK2 CCL4 PNRC1 ZBTB43 DUSP1 MAFF RASGEF1B AFF3 SNN NINJ1 TCTE3 ZCWPW1 KANK1 FRY ID4 CD80 IL6 SERPINB8 CPEB4 MN1 HSPA1B PLK3 RCAN1 PPP1R15A WTAP ELOVL7 FERMT2 CD83 IRF8 SELENBP1 OSM REL TNFRSF9 TPRA1 ACSL1 NIPAL4 EHD1 DUSP5 ATXN1 GPR84 SOD2 ADORA2A-AS1 MACF1 MBNL1 SOD3 CCL20 ICAM1 ANKLE2 IL18 MIER1 ABL2 NBN XIRP1 RIPK2 TOB2 TDRP TRAF1 NFKBIA EDN1 TNFSF9 KIF1B LDLR SFPQ PURB DNAJB5 TRIM36 DMXL2 PIM3 SPSB1 CDON SERPINE1 SVIL CLEC4E HES4 ARL4D ATP1B1 YRDC HEY1	down	***
LOPEZ_EPITHELIOID_MESOTHELIOMA	0.0037559	0.0325273	0.4317077	0.6339031	1.807749	16	HP PRR15L GRB7 GPR37 CLDN15 LRP2 ELMO3 UPK1B ANXA9 PTPRF	up	*
KEGG_HOMOLOGOUS_RECOMBINATION	0.0026699	0.0249752	0.4317077	0.5636300	1.806445	25	RAD54B XRCC2 TOP3B EME1 POLD2 RAD54L BLM SSBP1 RAD51D POLD1 RAD50 RPA1 RAD51 MUS81 TOP3A	up	*
HU_GENOTOXIC_DAMAGE_4HR	0.0029814	0.0269844	0.4317077	0.5422744	1.805947	30	NEK2 ANLN PTTG1 ECT2 PRC1 CDT1 BUB1 AURKA CDC25C ZSCAN21 SMG5 KIF22 COMMD7 IFNAR2 HLA-A CDC20	up	*
AKL_HTLV1_INFECTION_DN	0.0006792	0.0081346	0.4772708	-0.4167420	-1.804137	60	IL17RB PECAM1 GPR65 FYN YPEL5 VAPA ANXA1 SERINC1 REV3L CPVL HOPX FRY RWDD1 JUN TSPYL1 PKIA CD86 CD3G GPR171 DUSP6 ITGB1 SERP1 PTGS2 CCNC GZMB PNISR DNAJB6 GZMA UFL1 UBE2J1	down	**
NAKAMURA_ADIPOGENESIS_EARLY_UP	0.0005136	0.0066412	0.4772708	-0.4337302	-1.803919	51	INSIG1 FYN CCRL2 MYADM TGFBR3 LIFR CHMP1B GM2A PDE4D CYBRD1 FOXO1 SIK2 WASF3 ELK3 MT1L PIK3R1 IRS2 SOD2 CEBPD MT1M USP4 ZFP36 MT1E	down	**
PID_AP1_PATHWAY	0.0006792	0.0081346	0.4772708	-0.4162868	-1.802167	60	GATA2 FABP4 FOSL1 NR3C1 NFATC3 TCF7L2 BAG1 IL10 MAFG ATF3 DUSP1 ELF1 IL6 JUN ETS1 JUNB CREB1 FOS FOSB TGFB1 JUND EDN1 PTEN MT2A CSF2 EGR1 CDKN1B ATF2 IL5 EP300	down	**
MORI_PRE_BI_LYMPHOCYTE_DN	0.0004882	0.0063572	0.4984931	-0.3957030	-1.799819	73	LY86 SAMHD1 GPCPD1 S1PR1 CD22 CASP9 BTG2 MS4A1 CLK1 MCL1 NFKB1 PTPRC AKIRIN1 BTG1 RBM39 ATP6V0B FBXO11 RHOQ KLF2 MYL12A CD74 IAH1 CNR2 ZFP36 CD79B FCRLA CCNDBP1 PNRC2 JARID2 NFKBIZ FAM107B IL10RA CYTIP TANK TMEM71 ADCY7 LSP1 BLK RIOK3	down	**
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL	0.0000455	0.0008216	0.5573322	-0.3455078	-1.798834	147	CXCL3 SLC31A2 EREG BMP2 INSIG1 BDNF CD44 NEDD4L CITED2 LITAF KLF6 PTX3 KANK2 BTG3 TCF7L2 MCL1 TIPARP FOXO1 BIRC2 PLAUR ID3 THBS1 CDKN1A CXCL2 ID2 LBH DUSP1 INHBA MAFF TGFB2 IL6 JUN JUNB PTGER4 GLIPR1 CREB1 REL TNFRSF10B GPRC5A HIVEP2 GABARAPL1 TOB1 KYNU RGS2 RXRA CCL20 INTS6 NBN CALHM2 CEBPD DNAJB9 PDE8B LDLR PMAIP1 SPHK1 HERPUD1 SERPINE1 FJX1 HAS2 EFNB2 DNAJB4 HEY1	down	***
GUILLAUMOND_KLF10_TARGETS_DN	0.0046341	0.0384732	0.4070179	-0.5087403	-1.797994	25	GPD1 FCN1 AQP9 CYB5R3 TXNIP CD36 CTSS SRSF3 RCAN1 CHPT1 RTN4 PSME4 PAPSS2	down	*
BIOCARTA_VOBESITY_PATHWAY	0.0027723	0.0255527	0.4317077	-0.8379666	-1.797882	5	PPARG LPL NR3C1	down	*
KORKOLA_TERATOMA	0.0016739	0.0172431	0.4550599	0.5231202	1.796855	36	TSPAN8 PLAT CCNB1 LCN2 DNMT3B NUF2 CENPA AGR2 ZWINT AURKA EHF FEN1 DLGAP5 CDC20 MCM5 LRRC17	up	*
WACKER_HYPOXIA_TARGETS_OF_VHL	0.0025773	0.0244065	0.4317077	0.7163292	1.796828	11	CA9 CP PFKP PDK1 P4HA1 ADM HK2	up	*
GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP	0.0059861	0.0464687	0.4070179	-0.4646969	-1.793432	33	U2AF1 CHMP1B ANXA5 ATP6V1B2 HLA-DQA1 MAFF CREM STAT4 CD83 FXYD6 SDAD1 ZBTB44 VPS13D	down	*
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN	0.0020891	0.0205927	0.4317077	-0.4440965	-1.793091	42	HMOX1 DYRK1A RGCC SLC25A37 PDGFA RHOB RAB12 PTPRC IRAK2 ATP6V0D2 CCL4 INHBA NINJ1 CD80 CCR1 VASH1 TRAF1 SERPINE1 TNFSF8 NR4A2 MAMDC2 ZFP36	down	*
DODD_NASOPHARYNGEAL_CARCINOMA_DN	0.0000000	0.0000000	1.1421912	0.3492150	1.791571	1250	PRLR PCSK6 FAM83B TP63 DDX11 FOXM1 SLCO5A1 HELLS KIF20A HJURP CDC45 TICRR PARPBP MCM10 FANCI CHEK2 BUB1B NUP107 ZNF84 NEK2 CCNB1 CENPF TIMELESS POLQ FLVCR1 UBE2T PAIP1 CPSF6 COA1 PSPH GGCT MND1 PBK KIF18B COL27A1 TTF2 NDC80 PHF14 TSFM PRIM2 DEPDC1 BRCA1 PHGDH DEPDC1B CDCA7 C12orf66 ZNF138 METTL1 TTK GINS1 C6orf141 CDCA2 CDK4 RACGAP1 IQGAP3 KIF14 UBE2Z ANLN CCDC14 GMPS NIPSNAP1 AC011043.1 ASPM MMP1 FLAD1 NUF2 CENPA PTTG1 ECT2 CCL8 CDC6 SFXN1 TPX2 E2F3 GAPDH NNT CCNB2 FIGNL1 ANKRD22 RBBP8 FCGR3B UHRF1 KNOP1 MCM4 SPATS2 MCM2 RAD54B TYMS ZNF117 CDC25A UMPS PMS2 FERMT1 PRC1 COL22A1 CCNF EIF3B DTL CCT6A MCM8 KCNJ8 XPO5 MIS18A CAND1 SHMT2 RCCD1 XPOT ZWINT CCT2 SPDL1 AGK LSM5 NME1 RANBP1 CXCL10 C5orf34 TTLL4 KREMEN2 BZW2 CCDC150 MELK HMMR EXO1 NUDT1 C19orf48 KIF23 CEP55 CHAF1A MKI67 BOD1 KIF15 LINC00665 KNTC1 RHNO1 BUB1 CCDC77 EEF1E1 TOP2A CENPL HOMER3 DPY19L1 PUS7 AURKA EME1 ZNF112 NUP155 CBX3 WDR3 ATR VASH2 KIF2C MCM7 IFI44L RSRC1 MPHOSPH9 RRM2 GNAS-AS1 CDCA5 PRKDC RBM28 PDCD5 WDHD1 HOXC6 RAD54L MRPL3 ZNF146 KIF11 GPSM2 MCM3 CHAF1B LMNB1 CDC25C MCCC2 AIMP2 SOX4 YEATS2 BRI3BP PLXNA1 TMEM200C TOPBP1 CHEK1 ZNF618 DNAJC9 ORC6 MAD2L1 TRMT61B AHCY FBL CENPO RAD51AP1 DSCC1 BRIP1 CAD GNPDA1 RAD18 IPO9 CXCL9 PHB RGS4 ZNF587 TFCP2 CNPY2 SKP2 PSRC1 MARK1 CASP6 ZCRB1 CXCL11 KNSTRN CKS1B NCAPG2 NUSAP1 CBX5 URI1 ANAPC5 ZNF45 CDK1 CDK12 SSBP1 POLE2 CENPJ UCK2 CENPH BIRC5 ZNF260 CCT3 ATIC GMNN E2F1 UNG NCAPG VANGL2 TRAP1 DNA2 SLC25A13 DHX33 PSAT1 NEIL3 ANAPC7 FEN1 COL3A1 SSX2IP EZH2 NUP205 SPAG5 NF1 TTI1 NAPEPLD SNRPE NLN CBX1 UQCC2 NOP2 DIAPH3 ARNT2 DENND1A GBP5 LINC00173 PA2G4 RNASEH2A KPNB1 CHCHD3 POLR2H MYO19 FANCG UBFD1 INTS7 ILF2 CEP192 TRIM24 COL1A1 COL1A2 DLGAP5 ARHGAP11B ADAM12 CNOT2 ADNP DNAJA3 PUS1 C12orf45 SNRPA LMNB2 COL5A2 EPHB2 DUSP12 ZNF37A ZNF234 TK1 ADAR DTYMK C1orf131 CENPQ JMJD4 ESCO2 IL15RA GINS2 PDRG1 PKP4 KIF20B ASNS ANAPC1 FKBP14 SND1 C12orf73 NUP85 FAM200A MAGOHB CCZ1 SCNN1G ZNF140 SLC1A3 MARCKSL1 NT5M CDC7 YARS2 DHTKD1 CENPK SASS6 CKAP5 USP18 CPSF4 PSMB3 KLHL23 PALB2 C12orf65 FBXO22 AP3M2 MRPS23 FANCM MRPL24 MCM6 HOXA3 MGME1 ANKIB1 STAMBP RPL7L1 RAI14 PRMT1 CKAP2 XRCC4 HEATR1 SNRPD1 MALSU1 HAUS6 SNAP47 LTV1 SRSF1 C1orf109 GINS3 ZSCAN32 AATF EXOSC5 RTKN ETV6 CCNG1 TXNL4A VPS53 GAD1 ZNF780A DDX55 ATAD2 GOSR2 U2AF2 TSR1 CEP152 COPZ1 GTPBP10 NUP62 DPH5 CKAP4 ZNF286A INTS8 ADORA3 SUV39H2 ZNF519 PMS1 MSH2 TM7SF3 CCNA2 SMARCA4 PRIM1 ZNF195 PRR11 DENR RFC5 GBP1 NAV1 TUBGCP4 ABCF2 WDR4 RAD51 ZWILCH TRIP6 ST20 RASSF4 ARHGAP11A MRPL9 TARBP1 LLPH PAXIP1 ZNF121 CPOX UBAP2L LINC00839 ZNF131 SMC2 ZNF567 POLR1B CPT1C RNF213 CENPE TCF3 POLR1A DNAJC14 PFDN4 EARS2 DDX52 ROBO1 CBWD1 TRUB1 SEPHS1 PAICS PPIA EPHB4 UBE2C PNN NCAPD3 ANKRD46 FUT10 PWP1 OAS3 ENO1 RAD1 DNM1L ZNF367 C4orf46 CLASP1 CALU BRIX1 ARHGAP8 TIPRL ZNF562 CCL13 NCAPH ALKBH2	up	***
ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION	0.0000544	0.0009602	0.5573322	-0.3723079	-1.791246	106	CXCL3 IL1A IL1B GPR65 CCRL2 C5AR1 SLC15A3 BCL2A1 IL1RN PLA2G7 MAP3K8 LITAF TFEC MEFV BST1 PLAUR THBS1 CCL3 CXCL2 ATF3 SELL SELP FCER1G PLEK MAFF HCAR3 IL6 SOCS3 JUNB RCAN1 TREX1 GPR84 SOD2 CCR1 CCL20 CEBPD NFKBIA TNFSF9 CSF2 CSF2RB SERPINE1 CLEC4E	down	***
CHICAS_RB1_TARGETS_GROWING	0.0000028	0.0000677	0.6272567	0.3877580	1.790367	215	FOXM1 HELLS KIF20A BUB1B NEK2 CCNB1 CENPF TIMELESS PSPH DDIT4 DEPDC1 PHGDH CDCA7 TTK GINS1 IQGAP3 GTSE1 KIF14 GMPS ASPM CDCA8 CENPA AKR1C1 TPX2 CCNB2 FIGNL1 RBBP8 UHRF1 MCM4 MCM2 CA12 SHMT2 HMMR SMARCC1 BUB1 TOP2A TPR MCM7 MCM3 RBP1 DNAJC9 RAD51AP1 OXTR RGS4 IDH2 CASP6 NCAPG2 NUSAP1 TMEM106C CBX5 POLE2 CENPH GMNN NAV2 PSAT1 COL3A1 EZH2 RNASEH2A NRGN SSRP1 GINS2 ANP32E ASNS CDC7 CENPK PTN SUPT16H NFXL1 CDC20 OLFML3 MCM6 LRRC15 LRRC17 STMN3 MARCKS MSH2 CCNA2 PRIM1 CDC42BPA	up	***
VALK_AML_CLUSTER_5	0.0059461	0.0462370	0.4070179	-0.4971851	-1.787092	26	SIRPB1 SLC15A3 EPB41L3 PILRA LILRB3 PTAFR TFEB CD86 CCR1 UBE2D1	down	*
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN	0.0004431	0.0058389	0.4984931	-0.3931076	-1.786615	74	CXCL3 IL1B MIR22HG CD44 ERG ANXA5 HLX IL18R1 SPTBN1 TCF7L2 PTPRC CXCL2 SELL EVI2A INHBA HLA-DQA1 AREG CREM SH3BP5 RABGAP1 PTGER4 ENPP4 GLIPR1 IDS TCF4 TGFB1I1 SOD2 CLEC2B TFPI LIMCH1 FNBP1 DUSP6 SVIL	down	**
PID_PDGFRB_PATHWAY	0.0000971	0.0016047	0.5384341	-0.3566003	-1.786217	124	FYN BAIAP2 S1PR1 CBL FGR RHOA RAP1A PAG1 CRK STAT5A ACTR3 PIK3R5 ACTR2 HCK SRF PPP2CA WASF2 JUN RAPGEF1 PIK3R1 PRKCE GRB2 YWHAZ FOS MAPK8 MYOCD TAGLN JUND ARPC2 RAB5A ARPC5 PTEN DOCK4 GRB10 IQGAP1 SPHK1 ABI1 MAPK1 PIK3CG YWHAB SLC9A3R2	down	**
WINTER_HYPOXIA_DN	0.0022995	0.0223122	0.4317077	-0.4423698	-1.786120	42	LMO2 ABCB1 FLI1 EVI2B PTPRC EVI2A NCKAP1L ARL6IP5 SYNPO2 CD48 IRF8 GYPC CELF2 ICAM2 GIMAP1 CHPT1 PARM1 SLC25A20 ISCU IL16	down	*
BIOCARTA_G2_PATHWAY	0.0053521	0.0429029	0.4070179	0.5704295	1.786048	23	CHEK2 CCNB1 BRCA1 PLK1 CDC25A ATR PRKDC CDC25C CHEK1 MDM2 CDK1	up	*
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN	0.0002886	0.0040856	0.4984931	0.4366121	1.785146	86	FOXM1 CDC45 TROAP CCNB1 TRAIP AURKB CENPA PTTG1 CDC6 TPX2 CCNB2 MCM2 CCNF SMARCD3 MKI67 AURKA KIF2C MCM7 MCM3 RAD51AP1 DCLK1 CKS1B CDK1 EZH2 RECQL4 COL1A2 DLGAP5 TK1	up	**
WHITFIELD_CELL_CYCLE_G1_S	0.0002408	0.0034614	0.5188481	0.4154698	1.784688	115	MNX1 MDM1 DDX12P CDCA7 FLAD1 CDC6 UHRF1 MCM4 MCM2 CDC25A ORC1 DTL MAP2K6 TRIM45 CASP2 CHAF1A E2F2 CLSPN PASK CHAF1B HORMAD1 TOPBP1 TRMT2A DSCC1 MBOAT1 SKP2 RNPC3 GMNN E2F1 UNG VPS72 RECQL4 FANCG CCNE1 GINS2 AP3M2 ABCA7 MCM6 MCM5 GINS3 AP4B1 ATAD2 INTS8 MSH2 ZMYND19 WDR76 ADCY6 PNN ADCK2 ZNF367	up	**
VILIMAS_NOTCH1_TARGETS_UP	0.0022552	0.0219590	0.4317077	-0.4285975	-1.782993	47	PTCRA EGR2 BCL2A1 GATA3 NRARP BIRC2 ID2 CD80 JUNB CCR7 CD83 CD7 CD74 CD86 ICAM1 LAT TRAF1 NFKBIA CD3G EGR1 HEY1 CD69 TRAT1 GZMB IL10RA GZMA CD3D NFATC1	down	*
STEARMAN_TUMOR_FIELD_EFFECT_UP	0.0054713	0.0434007	0.4070179	-0.4748274	-1.782692	30	ACP5 LPL LILRB3 SIRPA APOC1 MPEG1 CTSD ITGAX CTSS SOCS3 CTSZ	down	*
ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF	0.0029511	0.0267687	0.4317077	-0.4457356	-1.781497	41	CLIC3 CITED2 CDC42EP2 ARHGAP29 CLCF1 LIFR KLF10 GLS RGCC CLK1 PXDC1 JAM2 INHBA GLIPR1 RNF24 GFPT2 TAGLN OSR1 HSPA8 SPHK1 EGR1 CHIC2	down	*
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN	0.0000212	0.0004261	0.5756103	0.4016625	1.781151	155	GRIP1 MMP13 SLC29A4 EYA1 LIPM AK4 PAX9 CCDC34 POLQ TRIM17 THEM5 FABP6 C4orf19 PRKCA RAD54B TNNT2 KCNH2 CLHC1 MYBPC2 THBS4 HAVCR1 SYT2 RIPK4 NEB EHF PSRC1 MYOT MB EPHA1 CENPH ATP2A1 NAV2 TNNI2 TRIM7 SMO FOCAD HSPA4L GDPD3 MC1R CCDC151 PCDH9 SMTNL1 CEP128 NR6A1 TEX21P RSPH10B RPGRIP1 UPK1B CKMT2 CABP7 ANKRA2 DPY19L2 STAC3 RSPH4A FARSA SCRG1 ELFN2	up	***
SEMBA_FHIT_TARGETS_DN	0.0025601	0.0242858	0.4317077	0.7275296	1.780611	10	CENPF ASPM ECT2 BIRC5 SPAG5 MNS1 DTYMK	up	*
RAMALHO_STEMNESS_DN	0.0010035	0.0114289	0.4550599	-0.4204034	-1.779700	56	ACVRL1 LY86 ST3GAL6 RTN3 MAL SLC11A1 BMP1 HDC PPP3CA SIRPA MPEG1 PTPRC CD53 EVI2A PPP2R5A CTSS TYROBP	down	*
WANG_CISPLATIN_RESPONSE_AND_XPC_UP	0.0000328	0.0006239	0.5573322	0.4040405	1.778451	141	CEACAM1 TF TRIP13 DDX11 IGF2BP3 PTPRN2 GGCT PLEKHH1 TTK SLC27A2 KIF14 BCAS1 MMP1 YEATS4 FIGNL1 GLDC PAH NCAPD2 AP1G2 SMARCC1 AURKA POLA2 KIF11 LIG1 MAD2L1 PPP5C FADS2 BMP5 KRT18 CDK1 BIRC5 PCP2 PMEL FEN1 ATAD3A RNASEH2A FANCG TELO2 ILF2 COL1A1 KIF22 KIF21A POLD1 FXYD3 CDC7 ZNF502 KRT8 MYEF2 IGLL5 CNTN2 PYCR1 CDH1 RFC5 RAD51 TARBP1 MXD3 RPN1 UBE2C NCAPD3 TTLL5 NUP93 ANKRD11	up	***
REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS	0.0050370	0.0408961	0.4070179	0.6230346	1.776754	16	FOXM1 CCNB1 CENPF PLK1 CCNB2 CDC25A MYBL2 CDC25C PKMYT1	up	*
LIN_MELANOMA_COPY_NUMBER_DN	0.0024885	0.0238521	0.4317077	-0.4509057	-1.776030	38	MED4 KLF6 CLN5 MTMR6 KPNA3 MARK3 ESD BAG5 MBP RPL21 TPT1 PTEN LPAR6 PAPSS2 SAP18 FNDC3A SUCLA2 EIF3J CDKN2A PROSER1 B2M	down	*
PID_CD8_TCR_DOWNSTREAM_PATHWAY	0.0036173	0.0316501	0.4317077	-0.4270379	-1.775983	48	FOSL1 NFATC3 CD8A PPP3CA PRF1 CD8B IL2RB JUN STAT4 JUNB PRKCE TNFRSF9 FOS MAPK8 IFNAR1 PPP3R1 CD3G EGR1 MAPK1 CD3E GZMB NRAS FASLG B2M CD3D NFATC1 IFNG	down	*
IGLESIAS_E2F_TARGETS_UP	0.0000517	0.0009183	0.5573322	-0.3551799	-1.774112	121	LYL1 LPL CDC42 CD9 GAS6 LMNA CSRP1 BZW1 LCP1 CLK1 CES1 RHOB CFD LIMS1 ITM2B DAB2 ZFAND5 LAPTM5 CADM1 CCND2 CAPZA2 DSTN GNAI2 CALM2 ANXA3 CTSS C1QA CTSZ TYROBP DNAJA1 SERPINB6 CD34 MORF4L1 CACYBP PKD2 CD74 AKIRIN2 HNRNPA2B1 COL15A1 APLP2 ACADL NPTN TIMM22 CDKN1C NFKBIA ACADM	down	***
CARD_MIR302A_TARGETS	0.0011619	0.0127785	0.4550599	-0.3948510	-1.773578	67	WEE1 SASH1 TGFBR2 ASAP1 FOXJ3 RB1 SRSF2 KLF9 CCND2 SMAD7 MBD2 PHTF2 PPP6C JUNB DDX5 EPC2 TSHZ3 CDC37L1 CNOT7 RBL2 EPHA4 FOXJ2 ZFPM2 EIF4G2 CLOCK RB1CC1	down	*
REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA	0.0040316	0.0343496	0.4070179	0.5530860	1.772651	25	BRCA1 RBBP8 XRCC2 EXO1 RAD51AP1 BRIP1 BLM DNA2 RAD51D RAD50 PALB2 RTEL1 RAD51 TOP3A RMI1 RMI2 RAD51B BARD1 WRN RAD51C	up	*
HALMOS_CEBPA_TARGETS_UP	0.0019037	0.0190057	0.4550599	-0.4370906	-1.769919	43	CXCL3 HMOX1 BMP2 FOLR1 FOXA2 PTX3 CXCL2 ARL4A BTG1 HCAR3 RGS2 ETS2 CCL20 BMP2K TNFAIP8 EPHA4 MEGF9	down	*
CHEN_ETV5_TARGETS_TESTIS	0.0052358	0.0422615	0.4070179	0.6159720	1.769524	17	HELLS AK4 CDCA7 MCM2 MKI67 HAUS6 RAD51 RBL1	up	*
WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP	0.0053541	0.0429029	0.4070179	0.6159037	1.769328	17	POLQ GTSE1 PLK1 CBX3 NCAPG2 FEN1 UCKL1 SUPT16H ATAD2	up	*
ZHANG_RESPONSE_TO_CANTHARIDIN_DN	0.0011856	0.0129109	0.4550599	0.4629928	1.767154	60	CDK4 SLC27A2 EIF3B RUVBL2 POLD2 MCM7 RRM2 MRPL3 ERCC2 HARS2 TRAP1 PA2G4 POLR2H FANCG RHOC TUBG1 SNRPA SUPT16H SNRPD1 FARSA PRIM1 RFC5 FARSB PGAM1 MTHFD1 SNRPC NDUFB2 PFKL CTPS1 EEF1D GTF3A RPSA ZNF200 IDH3A TIMM23	up	*
NAKAMURA_CANCER_MICROENVIRONMENT_DN	0.0020489	0.0202358	0.4317077	0.4976842	1.766740	42	TRIP13 FANCI PSPH CDCA2 CDC6 CCNB2 BUB1 AURKA KIF2C KNSTRN PSAT1 SPAG5 ARTN PA2G4 ASNS CDC20 LSM4 RFC5 USP39 TNS3 DHRS3	up	*
REACTOME_NEUTROPHIL_DEGRANULATION	0.0000000	0.0000003	0.7614608	-0.3018186	-1.764325	397	SIRPB1 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 MNDA LTA4H CAT RAB44 CLEC12A PTPRB OSCAR CD44 CHIT1 CYB5R3 PAFAH1B2 C5AR1 YPEL5 MANBA VAPA FUCA1 LAMP1 SLC11A1 LILRB3 FGR RHOA CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ASAH1 RAP1A GM2A ANPEP PTX3 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 RAB14 CD58 CST3 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE ARHGAP9 CD53 FCER1G GCA DEGS1 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP CTSS PSEN1 SNAP23 VAT1 RAB31 HK3 CTSZ TYROBP HSPA1B ATP11A RHOG ENPP4 GLIPR1 GMFG SERPINB6 CAP1 PSMD12 ALDH3B1 BIN2 CR1 MME TIMP2 SIGLEC14 DOK3 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ORM2 BRI3 PLEKHO2 ADAM10 IST1 COMMD9 UNC13D HSP90AA1 HSPA8 METTL7A NHLRC3 SIGLEC9 CTSC ARPC5 SNAP29 P2RX1 PSMD6 IQGAP1 CREG1 CNN2 ANO6 LYZ CYBA ATP6V0A1 CTSH TMEM30A ATP11B MAPK1 ITGAL FTL S100A8 RAB37 FPR1	down	***
SENESE_HDAC1_TARGETS_UP	0.0000000	0.0000006	0.7477397	-0.3026318	-1.761895	387	CXCL3 IL1A USP12 CD55 ROBO4 LPXN GPR65 BMP2 CD44 TMOD3 BACH1 LDB2 NEDD4L FOSL1 GPCPD1 GTF2I SLC39A8 RBM14 BCL2A1 OTUD4 TGFBR2 TRIB1 DNAJB14 GM2A CSGALNACT2 PTX3 SLC7A11 LCP1 SLAIN2 TOR1AIP1 JAM3 RB1 NFE2L2 SLC25A37 AKT3 SRGN TFRC MCL1 MYCT1 PTPN12 ITPRIP DUSP3 STX3 TPP1 LY96 ABCC4 CCL3 IRAK2 CCND2 PLEKHB2 PIK3C2A ELK3 UTP23 SLC6A6 IL7R BCLAF1 FKBP15 MAFF DEGS1 IL24 USP16 ACTR2 RAB6A CREM PHTF2 NSMAF PHACTR2 PNO1 SNAP23 RAB8B SERPINB8 SF3B1 CPEB4 ETS1 DESI2 CELF1 RAC2 ST6GALNAC4 ATP11A GLIPR1 PCGF5 IDS KBTBD8 COBLL1 ENTPD4 ATP13A3 CXCL5 OGFRL1 YWHAZ TNFRSF10B LETM2 MOB1A GPR3 RRN3 YTHDF3 PPTC7 AKIRIN2 STRN MTMR2 PDE12 DUSP5 NAB1 GALC MAP3K2 SOD2 KYNU GNA13 ADAM10 SERINC3 SNHG16 MBNL1 CCL20 GEM CEP170 TFPI CEBPD NLRP3 MEX3C PSME4 G3BP2 KPNA4 NFKBIA RASSF8 DOCK10 DUSP7 DNAJB9 DOCK4 NABP1 IQGAP1 SPOPL	down	***
DORN_ADENOVIRUS_INFECTION_48HR_DN	0.0037588	0.0325273	0.4317077	-0.4548119	-1.761384	35	NR4A1 NFE2L2 MCL1 MAP2K3 SRSF5 SDCBP IL6 BCAR3 SGK1 JUNB CD83 KLRC2 EWSR1 EPHA2 NFKBIA CYTH1 HNRNPH1 CCNK	down	*
WANG_RESPONSE_TO_ANDROGEN_UP	0.0063379	0.0485320	0.4070179	-0.4979853	-1.759984	25	ATXN3 INSIG1 HMGCR SPCS3 ACSL3 PIAS1 TRGC2 MED28	down	*
BIOCARTA_AMI_PATHWAY	0.0039964	0.0341022	0.4070179	0.6833628	1.759793	12	PLAT FGA PROC FGG	up	*
BENPORATH_ES_2	0.0044342	0.0372620	0.4070179	0.5397199	1.758141	27	HELLS MCM10 CHEK2 CDC25A MYBL2 ORC1 DSCC1 DBNDD1 EPHA1 L1TD1 DTYMK ETV4 RRP9 DNMT3A	up	*
LANDIS_BREAST_CANCER_PROGRESSION_DN	0.0014560	0.0153405	0.4550599	-0.3958367	-1.757974	64	CLEC3B THBD ST3GAL6 QKI ALAS1 GAS6 FZD4 ZEB1 AHNAK SORBS1 BNIP2 KLF4 PDE8A ADIPOR2 PPP2R5A VWF CD34 GNAI1 DECR1 MFNG FEZ2 MAP4 PHYH GHR	down	*
GAVIN_FOXP3_TARGETS_CLUSTER_P7	0.0008945	0.0103312	0.4772708	-0.3810747	-1.756656	81	SOSTDC1 DENND5A GLIPR2 ST3GAL6 BMPR2 MSRA AGPAT4 ABCB1 ANXA1 FAM89A RGCC IL10 SOCS2 ITIH5 SELP SHE PRF1 EVI2A KLRD1 SNN	down	*
PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP	0.0013890	0.0148225	0.4550599	0.4595959	1.754189	60	ABCC2 KIF20A HJURP CIB2 CDCA8 CENPA AKR1C1 TPX2 PRKCA TYMS CCT2 MCM3 SKP2 CKLF OSMR SUN1 KPNB1 UBFD1 SAP30 LRRC59 ASCC1 BCL2L1	up	*
CROSBY_E2F4_TARGETS	0.0020925	0.0205927	0.4317077	0.8376507	1.750542	6	BUB1B NDC80 PTTG1 CDC6 CHEK1	up	*
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN	0.0000000	0.0000001	0.7881868	0.3502226	1.749627	572	HMGA2 TRIP13 FOXM1 HELLS KIF20A CDC45 FANCI ELOVL6 CHEK2 BUB1B NEK2 COIL CCNB1 DNAJC12 CENPF TIMELESS POLQ COA1 GGCT CLGN NDC80 BRCA1 TUBB2B GINS1 GTSE1 HNRNPA1P3 SLC27A2 GMPS SNF8 ASPM STIL EIF2B5 NDUFS6 PLK1 AURKB CENPA AKR1C1 ESPL1 CDC6 SFXN1 GAPDH NNT CCNB2 MCM4 EXOC3 MCM2 SPINT2 RAD54B TYMS CDC25A PRC1 ORC1 AACS EIF3B ALDOC PLS1 GINS4 SHMT2 ZWINT COQ3 NME1 LDHB MELK HMMR DNPH1 NUDT1 MAP7 CEP55 CHAF1A SDHA MKI67 QTRT1 KIF15 PAFAH1B3 TOP2A CCT5 AURKA NUP155 NDUFS2 SLC2A10 POLA2 POLD2 YKT6 KIF2C MCM7 MAD1L1 RRM2 TTLL12 TFR2 WDHD1 RAD54L ENTPD6 KIF11 GPSM2 MCM3 CDC25C CD24 KDELR2 CHEK1 DNAJC9 CC2D1A PFKP TIMM50 BACE2 DSCC1 INPP4B FADS2 TST TADA2A ALDOA RECQL5 PES1 CKS1B CMAS HPS4 NUSAP1 TMEM106C PLOD2 CDK1 EXOSC2 SNX4 BIRC5 ATIC AAGAB NCAPG TRAP1 PSMB5 PSAT1 FEN1 SPAG5 ETFB RECQL4 ITGA2B LAPTM4B QPRT KPNB1 RANGAP1 CHCHD3 SNRNP25 DNAJC17 DLGAP5 ZNF671 GSS PUS1 LMNB2 AARSD1 ADAM28 UROS PTGES2 KIF22 SSRP1 ARL6IP4 ZNF544 TK1 GINS2 ENOSF1 PRMT7 FHL2 NADSYN1 CCT7 DHTKD1 RMND5B KLHDC3 CDC20 CENPM RRP9 ACLY RPA1 MRPL28 SRPK2 MCM5 CD2BP2 HMCES AATF DUS4L RAP2B NEFH CBR1 TSR1 CKAP4 NDUFV1 DDAH1 GLO1 CCNA2 PRR11 VDAC1 CDC42BPA ABCF2 UQCRC1 LPIN1	up	***
REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX	0.0010636	0.0119679	0.4550599	0.4534920	1.749282	62	CDC6 E2F3 MCM4 MCM2 ORC1 MCM8 CDT1 MCM7 E2F2 MCM3 ORC6 PSMD4 GMNN E2F1 PSMB5 PSMC4 PSMA5 PSME2 PSMD2 PSMB3 MCM6 MCM5 PSMB4	up	*
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP	0.0011227	0.0124968	0.4550599	-0.3844000	-1.748408	73	FGR GATA3 SPTBN1 TLE4 YBX3 FUT7 ID3 LAPTM5 VIM SELL DSTN BTG1 TRGC2 DDX5 CD34 MME TCF4 TSC22D1 FCGRT SPOCK2 SERINC3 CLEC2B TIAM1 CCR9 SREBF2 BMI1 CTSH CX3CR1 TUBA1A CD3E NFIL3 IL32	down	*
SCHLOSSER_SERUM_RESPONSE_DN	0.0000000	0.0000000	0.8753251	-0.2887289	-1.746766	615	HCRTR1 KMO SC5D SECISBP2L CD55 FCN3 MNDA CYP27A1 CAT SLC16A4 PTP4A2 INSIG1 RUNDC3B COQ2 BACH1 GTF2E2 MYD88 SLC39A8 IDI1 CIR1 HMGCR DYRK1A PRKAR1A MEF2A ELMO1 MANBA CD9 HPS5 RCHY1 ZEB2 EDEM1 KCNAB1 TRA2B ADAM17 RAP1A EIF1 BZW1 EIF5 SERINC1 REV3L TOR1AIP1 PPP3CA SIRPA RB1 TMEM123 NFE2L2 ZFYVE16 ITSN2 TCAP GPM6A PPP3CC ADARB1 HMGN1 SCP2 SRSF5 HNRNPA3 SDCBP CASP1 KLF4 FAM76A LEPROTL1 ZFAND5 MAP1LC3B TMED5 MED6 CLIC4 LY96 SEC24B PDE8A PTPRC DUSP11 EPS15 EVI2A MBD2 DSTN PAFAH1B1 BCLAF1 SMNDC1 TP53BP2 CALM2 CRIM1 ACTR2 TDRD7 HEXB SACM1L NCKAP1L SERTAD2 PDK4 SLC25A3 RYBP CDC40 GABARAPL2 PGD DCTN6 RBM34 NEK7 PIKFYVE PPP6C SF3B1 PSMA1 CUL4A USO1 MTMR9 TMEM251 WTAP SNX2 SDHD HSPA13 DDX5 GMFG MORC3 TPP2 RNF24 DLEU2 YWHAZ NDST1 SNRK WDR7 CACYBP CD164 PTP4A1 PSMD12 MSMO1 ICAM2 MYL12A AZIN1 STXBP3 EPB42 HNRNPA2B1 NIPA2 LSM6 PHF3 NDUFA5 DCK PDS5B UTP3 PPIG TOB1 STX12 DECR1 NPTN CLASP2 CRY1 MAGOH ACYP2 PHF2 PGGT1B ADAM10 SERINC3 ETS2 MBNL1 ATAD2B CCNH GTF2B RBL2 ARAP2 LDLRAD4 YAF2 CCDC69 CGRRF1 NBN MGAT2 NT5C2 SEC63 RTN4 RAB5A USPL1 SEC61B DHRS12 ARIH1 TBC1D1 SP100 MEGF9 BCAM CREBBP GLUL COPS8 ACADM PAK2 FDFT1 MMD LDLR PSMD6 CREG1 NUP160 EID1 RSU1 ATF4 BMI1 EVI5 PMAIP1 LYZ SLC35A1 DMXL2 SNRPG HAT1 YTHDC1 ABI1 PSIP1 KALRN PLAG1 UBR2 CLIP1 ATP11B HIPK1 ATF2 ZNF259P1 SH3GLB1 RB1CC1 FAM8A1 CBR4 EFS PPWD1 PPIP5K2 SRSF11 IFIT5 PPFIA1 LAMTOR5 UBE3A KIDINS220 AKAP12 CAPZA1 CDK7 RAD21 PCMT1 NMI DLD FANCC EP300 ATP8A1 RCBTB2 SMARCA5 POLR2B	down	***
REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND	0.0053456	0.0429029	0.4070179	0.6387299	1.746079	14	PRIM2 POLA2 POLD2 LIG1 DNA2 FEN1 POLD1 RPA1 PRIM1	up	*
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP	0.0025433	0.0242095	0.4317077	-0.4311820	-1.745993	43	IL17RB TAL1 TIE1 HSPE1 HSPB1 JAM3 KANK2 SOCS2 MPL NPR3 SNN CDK17 GNAI1 MEIS1 MACF1	down	*
REACTOME_EXTENSION_OF_TELOMERES	0.0034232	0.0303048	0.4317077	0.5003761	1.745528	38	RUVBL1 PRIM2 PIF1 RUVBL2 POLA2 POLD2 LIG1 DSCC1 BLM DNA2 FEN1 CHTF18 POLD1 RPA1 CHTF8 PRIM1 RTEL1 RFC5 NHP2 POT1 CTC1 POLD3 RFC3 RFC4 PCNA WRN	up	*
REACTOME_TELOMERE_MAINTENANCE	0.0034232	0.0303048	0.4317077	0.5003761	1.745528	38	RUVBL1 PRIM2 PIF1 RUVBL2 POLA2 POLD2 LIG1 DSCC1 BLM DNA2 FEN1 CHTF18 POLD1 RPA1 CHTF8 PRIM1 RTEL1 RFC5 NHP2 POT1 CTC1 POLD3 RFC3 RFC4 PCNA WRN	up	*
REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	0.0000645	0.0011159	0.5384341	0.3964844	1.745192	141	CDC45 MCM10 CCNB1 PRIM2 CDK4 POLE CDC6 E2F3 TFDP2 MCM4 MCM2 TYMS CDC25A MYBL2 ORC1 MCM8 CDT1 TOP2A POLA2 MCM7 E2F2 RRM2 MCM3 ORC6 PSMD4 AKT2 MNAT1 SKP2 CKS1B CDKN2C CDK1 POLE2 GMNN E2F1 PSMB5 PSMC4 CCNE1 PSMA5 PSME2 TK1 HDAC1 LIN37 PSMD2 CDC7 PSMB3 RPA1 MCM6 MCM5	up	**
REACTOME_S_PHASE	0.0001045	0.0016870	0.5384341	0.3944927	1.743996	149	CDC45 PRIM2 GINS1 CDK4 POLE CDC6 TFDP2 MCM4 MCM2 CDC25A ORC1 MCM8 GINS4 CDT1 POLA2 POLD2 MCM7 CDCA5 MCM3 LIG1 ORC6 PSMD4 AKT2 MNAT1 SKP2 CKS1B ANAPC5 POLE2 E2F1 PSMB5 DNA2 ANAPC7 FEN1 PSMC4 CCNE1 CDC23 PSMA5 PSME2 ESCO2 GINS2 FZR1 LIN37 ANAPC1 POLD1 PSMD2 PSMB3 RPA1 MCM6 MCM5 GINS3 PSMB4 CCNA2 PRIM1 ANAPC2 RFC5	up	**
CHYLA_CBFA2T3_TARGETS_UP	0.0000002	0.0000079	0.6749629	-0.3091856	-1.742880	311	SLPI TEK OLR1 ENDOU CCM2L HVCN1 TMEM150B FBP1 F2RL3 RAB44 CLEC12A GPR65 AATK ESAM PLEKHA1 TBXA2R CLEC10A ALAS1 NCF2 TET2 IGSF6 PDE2A SIGLEC6 MCTP1 SGMS2 C1orf21 ANXA5 ABCG1 HDC LCP1 CD93 SPTBN1 TFEC ARHGEF2 SPI1 ARL11 MYCT1 TMEM38B ATP10A RHOB EVI2B FABP5 CSRNP1 SPNS3 MEFV NOSTRIN PPM1K CASP1 GCHFR AFAP1L1 DRAM1 SOCS2 ITIH5 GMPR LAPTM5 DOCK9 HPSE CXXC4 CCND2 TM6SF1 ALOX5AP GCA DSTN UBASH3B HLA-DQA1 ANXA3 BACE1 ARHGDIB FLT1 TMOD1 KLRB1 CABLES1 CD48 VAT1 RAB31 HK3 TREM1 ELOVL7 GMFG PTGER2 GPRC5A RALB CST7 CELF2 CD34 PLCG2 RHOQ	down	***
FINETTI_BREAST_CANCERS_KINOME_BLUE	0.0054361	0.0431836	0.4070179	0.5767535	1.742546	20	STK36 NEK11 EPHA10 IKBKB DCLK1 ACVR1B ERBB3 STK39 ULK4 MAP3K12 GAK STK32B IGF1R	up	*
KEGG_CHEMOKINE_SIGNALING_PATHWAY	0.0001203	0.0019117	0.5384341	-0.3334471	-1.741902	151	CXCL3 CXCL16 ADCY9 ADCY4 CCL3L1 ELMO1 CDC42 FGR RHOA RAP1A GNGT2 GNG7 CRK AKT3 ROCK2 ARRB1 CCL22 ROCK1 GRK5 CCL3 NFKB1 CXCL2 SHC4 CCL4 XCL2 PIK3R5 GNAI2 HCK ADCY2 RAC2 CCR7 PIK3R1 GRB2 PRKACA CXCL5 FOXO3 CCR4 VAV3 GNAI1 GNG5 GNB4 CCR1 GRK4 CCL20 CCR6 ARRB2 TIAM1 CXCR4 CCR9 NFKBIA	down	**
WAKASUGI_HAVE_ZNF143_BINDING_SITES	0.0025186	0.0240579	0.4317077	0.4766030	1.741663	49	CHEK2 BRCA1 POLE PMS2 EXO1 PRKDC FANCD2 CHEK1 RAD18 RECQL5 FEN1 RECQL4 FANCG RAD9A POLD1 POLB TDP1 MSH4 PMS1 MSH2 XPC TP53 APEX1 RAD1 MUS81	up	*
MIKKELSEN_NPC_WITH_LCP_H3K27ME3	0.0060748	0.0467767	0.4070179	-0.8113696	-1.740817	5	CCM2L PRELP GSDMA	down	*
MEISSNER_BRAIN_HCP_WITH_H3K27ME3	0.0002026	0.0029834	0.5188481	0.3962361	1.739599	138	HMGA2 SIM2 MNX1 SLC5A5 HOXD8 IGF2BP3 HOXB6 NPAS1 PKP1 FOXE1 IRX6 SIX1 HOXB7 IGFBPL1 INSRR SPAG16 CBLC CYP24A1 THBS4 RSPO4 B3GNT3 PROM2 SPINT1 HOXB5 TRPV4 KRT18 DMGDH PRRX2 SPAG6 SLC44A3 WDR86 IRF6 TBX1 CRLF1 ALX4 SALL4 GRIN3B ECEL1 KRT19 TMEM30B MARCKSL1 NAGS HNF1B CHMP4C WNT10B ADAMTS14 CHRNA3 IL12RB2 CDCP1	up	**
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_21	0.0007659	0.0090740	0.4772708	0.9259679	1.739119	4	HMGA2 CDK4	up	**
RUTELLA_RESPONSE_TO_HGF_UP	0.0000001	0.0000021	0.7195128	-0.2990842	-1.738293	380	CXCL3 ACP5 KMO SC5D IL1A OSBPL1A IL1B FBP1 CYP27A1 SNX10 DCSTAMP LPXN RDX CCRL2 ST3GAL6 AQP9 ALAS1 CD9 LAMP1 EPB41L3 RFTN1 TEX2 PLA2G7 MCTP1 ASAH1 ENTPD1 GM2A CSRP1 CYB5A TNIP3 HSPB1 ANXA5 LITAF ABCG1 GLS SLC7A11 STOM LAIR1 AKT3 CRTAM CES1 ZFYVE16 TFRC TXN ATP6V1H APOC1 CD58 EPB41L2 IL10 CCL22 KCNMA1 ACSL3 KLF9 DAB2 CTSD CCL3 CDS2 CTBS TM6SF1 CCSER2 INHBA PINK1 MATK ZNF706 N4BP1 TBC1D4 CRIM1 HEXB ARL6IP5 CD80 PKNOX1 SGK1 RAB8B PDCD6IP C1QA MITF VAT1 LTBP2 DUOX1 JAK1 TMEM251 CCR7 ZNF804A ATP13A3 CXCL5 MOB1A SLC3A2 POGLUT1 GRSF1 RHOQ NKG7 RIN2 EMC7 TIMP2 TFEB TSC22D1 DUSP5 DYNC1LI1 CD81 SOD2 LGALS3 CCR1 KYNU IL18 TNFAIP8 SLC31A1 CALHM2 ATP9B TBC1D1 TRAF1 PLGRKT FDX1 BCAT1 CD1E FOXJ2 LDLR DOCK4 MT2A CREG1 ARFGAP3 ACAT1 SPHK1 DMXL2 ATP6V0A1 TMEM184C PHYH	down	***
REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	0.0017084	0.0174350	0.4550599	-0.3889177	-1.737162	65	EREG CAV1 HBEGF GNGT2 HSPB1 CAV2 GNG7 AKT3 EPGN GNAI2 SRF AREG PIK3R1 CREB1 FOS CALM1 FOXO3 STRN GNAI1 GNG5 GNB4 HSP90AA1 ZDHHC21 SPHK1 CDKN1B MAPK1 GNG11	down	*
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN	0.0000000	0.0000001	0.7749390	-0.2935177	-1.735921	461	SIDT2 ARHGAP31 SASH1 EDNRB HHEX TBX3 GLIPR2 SLC16A4 ST6GALNAC3 PTPRB STXBP6 ELF2 PRKAR1A NEDD9 GALNT18 NFATC3 TRIB1 SCARA3 TEX2 SNHG5 KCNAB1 MMRN2 FBXO7 LIFR ASAH1 CSRP1 NLK FOXP1 CAV2 CLN5 STOM FAM122A HNRNPDL TNS1 SPTBN1 PPP1R13B EPM2AIP1 CYP4V2 UBE2D3 CYB5D2 GPM6A ZMIZ1 CYBRD1 FOXO1 SAP30BP DENND6A TSPAN12 ZCCHC24 KLF9 SLC7A8 GRK5 FMNL3 NPAS3 TEF CD302 LBH WASF3 PINK1 MATN2 WFS1 MPC1 GNAQ ZNF706 RUFY3 HES1 SNN HGSNAT MYLIP SLC25A3 IL17D FRY PRDM11 SYNPO2 PKNOX1 SGK1 CTSS PHACTR2 MAGI2 PPP6C AQP3 CYB5R1 KCTD12 BTD PODXL HERC1 SNX1 LPCAT2 SNX22 NIPSNAP3B SNRK TOM1L2 MCAM FOS CALM1 PKIA CHPT1 DDHD2 TCF4 NDUFA5 GNAI1 MIA3 MPV17L MEIS3P1 PLSCR4 ANKRD13A TOB1 STX12 SBSPON RIMKLB N4BP2L2 KAT2B ABI3BP RXRA SESN1 GPX3 SLC35D2 PDLIM5 CPQ PARM1 CEBPD ATP9B EIF4EBP3 NSUN4 TBC1D1 BRWD1 GPD1L BCAM RBMS3 CCDC92 TIMP3 PDE4A RNF38 MTUS1 PRKG1 GSPT1 ENY2 SMAD4 FEZ1 BANK1 PAPSS2 FNBP1 CBX7 STARD13 PHYH EGR1 CDON GHR NR4A2 MAMDC2 NDFIP1 FAM53B CBR4 COX20 HEY1 ABHD14A PEBP1 RMDN1 KIDINS220 AKAP12 POLI MAN1A1 ATOH8 SNRPN MAP3K1 KLHDC1 ZFYVE21 ECHDC3 NKTR AKAP13 SKP1 TPST2 BMPR1A ERLIN2 EIF4E3 ALDH3A2 ST3GAL1 GSN AP4S1 WDFY3-AS2 ZFHX3 RASSF5 CPNE3 RCAN3 TCTA TMEM150C CSGALNACT1 EED ZC2HC1A SRRD RGS5 FARP1 RASSF8-AS1 TMEM64	down	***
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP	0.0000467	0.0008399	0.5573322	0.3856424	1.735715	175	TRIP13 HJURP FANCI NUP107 COIL NDC80 TTK CDC6 EIF3B NCAPD2 CCT2 NME1 MELK HMMR NLE1 CEP55 BUB1 CCT5 PUS7 NUP155 CBX3 KIF2C RBM28 PFN2 TOPBP1 ACTL6A MAD2L1 RAD51AP1 PHB CKLF NSF PLOD2 UCK2 ATIC NCAPG SEC61G KIF2A EZH2 PSMC4 KPNB1 TPD52L2 TACC3 ANP32E KDM3A CENPM LRRC59 UBE2V2 MED24 C5orf22 WDR45B MARCKS WDYHV1 PRMT5 CCNA2 PRIM1 CANT1 SNRPD2 SNX7 ZWILCH DNAJC10 HGS GPN1 PWP1 ENO1 CYB5B MRTO4 SRM UTP18 ADSL LPCAT1 SRI	up	***
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN	0.0002121	0.0031068	0.5188481	0.4015726	1.735376	126	RHPN2 ANKRD36C GRIK2 PCDHGA10 CPLX2 ZFHX4 PCDHGA9 COL27A1 TSHZ2 PCDHGA7 CHST4 PHGDH PCDHGA6 ANLN PCDHGB3 PCDHGB6 PCDHGB4 COCH APOL2 ANKRD36B KIAA0895 PCDHGA11 PCDHGA8 KIF15 PCDHGC5 PCDHGC4 PCDHGB7	up	**
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN	0.0001752	0.0026434	0.5188481	-0.3521315	-1.734569	113	CXCL3 SLPI ACP5 ACE ADTRP PID1 FCER1A CHIT1 C5AR1 CD9 FUCA1 PLA2G7 RNASE1 DACH1 RGCC SGTB ID3 DAB2 SLC7A8 CCL3 RIT1 CXCL2 ATP6V0D2 CCL4 FRMD4A PTGER3 IL7R ANXA3 RPS6KA2 PDK4 SGK1 SLCO2B1 TMTC1 C1QA	down	**
LIANG_SILENCED_BY_METHYLATION_DN	0.0062947	0.0482684	0.4070179	0.7214635	1.729127	9	FOXM1 MCM2 MKI67 KIF11 EZH2 CCNA2	up	*
NIKOLSKY_BREAST_CANCER_20Q12_Q13_AMPLICON	0.0005459	0.0068810	0.4772708	0.4037759	1.725977	111	RBBP8NL ZMYND8 TSHZ2 BCAS1 TOMM34 LIME1 ZFP64 OSBPL2 CYP24A1 C20orf197 AURKA SYCP2 FAM209A SAMD10 ZNF512B ABHD16B DIDO1 BCAS4 PRPF6 UCKL1 TPD52L2 ZGPAT ARFRP1 MRGBP ADNP ATP9A SALL4 CABLES2 TCEA2 LSM14B PPP1R3D GID8 STMN3 OGFR ARFGAP1 RTEL1 ZNF217 ADRM1 PFDN4 TAF4 NPEPL1 ZNF831 ZBP1 MTG2 SS18L1 PMEPA1 CSTF1	up	**
LI_WILMS_TUMOR_ANAPLASTIC_UP	0.0065889	0.0499688	0.4070179	0.6306275	1.723930	14	CENPF TTK CENPA MKI67 KIF2C RAD54L NUSAP1	up	*
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1	0.0046067	0.0383032	0.4070179	-0.4310540	-1.722818	41	KRT81 EREG FOSL1 TRIB1 HBEGF MALL SLC7A11 SHC4 ELK3 MAFF AREG PLK3 SPRY4 DUSP5 GEM EPHA2 LPAR6 REEP1 EGR1 DUSP6	down	*
REACTOME_FICOLINS_BIND_TO_REPETITIVE_CARBOHYDRATE_STRUCTURES_ON_THE_TARGET_CELL_SURFACE	0.0053193	0.0428730	0.4070179	-0.8762405	-1.722382	4	FCN1 FCN3 MASP1	down	*
REACTOME_M_PHASE	0.0000022	0.0000561	0.6272567	0.3569685	1.719726	317	CEP72 KIF20A BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TUBB2B CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CCNB2 PRKCA DYNC1I1 NCAPD2 ZWINT DCTN2 SPDL1 HAUS5 CEP250 KIF23 KNTC1 BUB1 CENPL NUP155 ODF2 SFI1 TPR KIF2C MAD1L1 LPIN3 CDCA5 LMNB1 MAD2L1 PSMD4 CENPO SPC24 INCENP NCAPG2 ANAPC5 CDK1 CENPJ CENPH BIRC5 NCAPG PSMB5 KIF2A ANAPC7 NUP205 DYNLL2 PSMC4 CENPP FGFR1OP KPNB1 RANGAP1 MZT2A MZT2B CEP63 CEP192 CDC23 TUBG1 PSMA5 NINL TUBB2A PSME2 TUBA3D TUBA8 CENPQ ANAPC1 PSMD2 NUP85 CENPK CKAP5 PSMB3 CDC20 CENPM TUBG2 AAAS CHMP4C CDK5RAP2 DYNC1LI2 CENPT HAUS6 RCC1 HAUS4 PSMB4 CEP152 NUP62 ALMS1 BANF1 ANAPC2 TUBGCP4 CEP164 LPIN1 TUBA4B ZWILCH SEC13 NME7 CHMP2A SMC2 MAU2 CENPE GOLGA2 LEMD2 UBE2C NCAPD3 TUBA1C PPP2R5D NUP210 CLASP1 NUP93 NCAPH CEP290 CHMP6 DYNC1H1 PLK4 AKAP9 PCNT DSN1 PPP2R5E FBXO5 PSMB10 TUBGCP2 PSME1 NSL1 TMPO	up	***
HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN	0.0060731	0.0467767	0.4070179	0.5151605	1.718360	31	RHPN2 PRSS2 BAMBI TRIB3 ASTN2 CEL MSX1 ASS1 IGSF21 IGFBP5 PPIC TESC	up	*
REACTOME_CA2_PATHWAY	0.0025285	0.0241107	0.4317077	-0.4020629	-1.717872	57	PRKG2 GNGT2 NLK FZD4 PPP3CA GNG7 TCF7L2 AGO4 AGO3 PDE6A PDE6B CALM1 WNT11 GNG5 PPP3R1 GNB4 TCF7L1 PRKG1 GNG11 WNT5A PDE6G PLCB2 ITPR2 AGO2 NFATC1 GNG2 TNRC6C AXIN2	down	*
REACTOME_GLUCONEOGENESIS	0.0054080	0.0430747	0.4070179	0.5531649	1.717056	22	GPI GAPDH ALDOC ALDOA SLC25A10 GOT2 ALDOB SLC25A13 G6PC3 SLC37A4	up	*
PID_AMB2_NEUTROPHILS_PATHWAY	0.0060011	0.0464687	0.4070179	-0.4450398	-1.716471	34	FYN FGR RHOA RAP1A JAM3 PLAUR ROCK1 NFKB1 SELP JAM2 HCK IL6	down	*
PID_KIT_PATHWAY	0.0027101	0.0251780	0.4317077	-0.4086545	-1.714287	50	CBL SH2B3 STAT5A EPOR PTPRO MATK MITF PIK3R1 GRB2 FOXO3 MAPK8 TEC CREBBP KIT PTEN GRB10	down	*
PID_E2F_PATHWAY	0.0011755	0.0128519	0.4550599	0.4389032	1.713574	67	BRCA1 CDC6 E2F3 TFDP2 RBBP8 TYMS CDC25A MYBL2 ORC1 RANBP1 WASF1 E2F2 RRM2 TRRAP MCM3 TOPBP1 XRCC1 CDKN2C CBX5 CDK1 E2F1 CCNE1 TK1 CASP7 HDAC1	up	*
DAZARD_RESPONSE_TO_UV_SCC_UP	0.0008760	0.0101610	0.4772708	-0.3657013	-1.713220	85	CXCL3 SC5D IL1B MIR22HG CITED2 PRKAR1A ANAPC15 SLC11A1 UBE2D3 ITM2B CXCL2 ATF3 ID2 ANXA3 ARHGDIB SNX3 IL6 SDHD YWHAZ RALB FOS TOB1 KYNU ME2 CCL20 JUND RTN4 CDKN1C SRSF10 PMAIP1 CSF2	down	*
PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN	0.0002998	0.0042219	0.4984931	-0.3402809	-1.712857	128	TMEM100 SECISBP2L CD44 PLEKHF2 TGFBR3 TRIB1 CCNL1 ARHGAP29 ECHDC1 ZNF410 KLF6 NDEL1 HNRNPDL LAMTOR3 BAG1 EPB41L2 MTMR6 ID2 DUSP1 EXOSC8 N4BP1 TP53BP2 NRBF2 RABGGTB ZNF330 MOB4 RYBP DCTN6 RBM34 TRAK2 CEBPZ ZBED5 ING3 BCAS2 TEX30 ZCCHC10 CCNH CCL20 AMD1 TNFAIP8 CGRRF1 CDC42EP3 GTPBP8 LDLR C1orf115 HAT1 SH3GLB1 HEY1 ANKHD1 CDK7 WWTR1 TAF1D ORC4 AIMP1 RAB11FIP2 PTGS2 BTBD1 NOL11 IVNS1ABP ARFGAP2 UQCRB LEPROT	down	**
REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION	0.0016740	0.0172431	0.4550599	0.4217994	1.712047	82	CHEK2 BRCA1 AURKB TPX2 RBBP8 EXO1 RHNO1 AURKA ATR TOPBP1 CHEK1 MDM2 BRIP1 BLM DYRK2 DNA2 TAF6 PRKAA2 STK11 RAD9A SSRP1 NOC2L RAD50 SUPT16H RPA1 CCNA2 RFC5 CDK5 TP53 TAF4 RAD1 PRKAG1 TOP3A ATRIP RMI1 TP53RK PRKAB2 RMI2 PRKAA1 RFC3 BARD1 RFC4 MAPK14 MAPKAPK5	up	*
FALVELLA_SMOKERS_WITH_LUNG_CANCER	0.0026268	0.0247062	0.4317077	-0.3777392	-1.711632	68	EPAS1 ENG OTUD4 B3GNT5 EIF1 BTG2 AHRR RNF144B RNF125 MCL1 RHOB RAB12 SRSF5 AQP4 ATP6V0D2 DUSP1 MYH11 ACTR2 UFM1 RCAN1 SOD2 CCL20 WDR1 PRKG1 CYTH1 IQGAP1 SERPINE1 FUS SCAF11 MATR3	down	*
LIM_MAMMARY_STEM_CELL_UP	0.0000000	0.0000004	0.7477397	-0.2920753	-1.709493	410	LIMS2 EPAS1 PRX WTIP STAC EDNRB RASIP1 CSDC2 IL1B LRRC8C TIE1 THSD1 PTPRE EGR2 BACH1 CAV1 AQP9 QKI CDH13 CDC42EP2 TGFBR3 EOGT AGPAT4 HSPG2 HEG1 CD36 TBX2 PLA2G7 BMP1 LTBP4 TACC1 LIFR PLXNA2 TMEM204 LUZP1 FOXP1 TTYH2 JAM3 TNS1 AKT3 SRGN PDGFA TUBB6 CNN1 LRP4 ADARB1 FABP5 AMOTL1 KCNMA1 SORBS1 PEG3 PXDC1 SLC12A4 ZNF423 THBS1 ARNTL SSH1 CDKN1A CADM1 TMEM255B KCNMB1 VIM AXL JAM2 ARC RECK IGFBP2 LBH SHE CCND2 ELK3 MATN2 ACTG2 PRICKLE2 MYH11 DCHS1 IL24 MRVI1 RASL12 MEDAG CNRIP1 ID4 SCN4B IL6 PODN CCDC3 ETS1 MSRB3 ELP5 RHOJ RAPGEF1 FERMT2 GYPC MALT1 GRASP COL23A1 MCAM GPR3 TSHZ3 FLNC MME ISM1 TCF4 ITGA9 CYGB TGFB1I1 CTNNAL1 GNAI1 GNB4 MYOCD MRGPRF SBSPON MFNG ABI3BP TCF7L1 TAGLN MBNL1 GEM ICAM1 YAF2 LMOD1 PAMR1 OSR1	down	***
AMIT_EGF_RESPONSE_60_MCF10A	0.0060011	0.0464687	0.4070179	-0.4425845	-1.707002	34	DLC1 SOWAHC TRIB1 IER2 KLF7 CXCL2 INHBA HES1 IL6 JUN JUNB PTGER4 GLIPR1 SLC35D2 PDLIM5	down	*
REACTOME_AURKA_ACTIVATION_BY_TPX2	0.0018527	0.0185644	0.4550599	0.4407263	1.706425	65	CEP72 NEK2 CEP70 PLK1 TPX2 DCTN2 HAUS5 CEP250 HMMR AURKA ODF2 SFI1 CDK1 CENPJ FGFR1OP CEP63 CEP192 TUBG1 NINL CKAP5 CDK5RAP2 HAUS6 HAUS4 CEP152 ALMS1 CEP164 CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT	up	*
PYEON_HPV_POSITIVE_TUMORS_UP	0.0018228	0.0183311	0.4550599	0.4202677	1.705830	82	LINC00342 HELLS SLFN13 ABCA17P CENPF CDCA7 UHRF1 TYMS DTL MCM8 C5orf34 STAG3 KIF15 KNTC1 SYCP2 MPHOSPH9 MCM3 LIG1 KLHL35 CDKN2C CENPJ ZNF789 EZH2 MIR3939 INTS7 CDK3 CDC7 CENPK MEI1 FBXO22 TRIM56 ATAD2 ZSCAN16 TM7SF3 WDR76 MON2 E2F7 ZNF367	up	*
LI_INDUCED_T_TO_NATURAL_KILLER_UP	0.0000019	0.0000481	0.6435518	-0.3042084	-1.703241	275	CD52 GPR15 SCIMP HVCN1 HHEX GLIPR2 TMEM126A LRRC8C CLDND1 CTSW GFOD1 ST3GAL6 CORO1C AQP9 STX11 CD9 KLHL30 ARSB LMNA ASAH1 C1orf21 SERP2 EMILIN2 IFI30 LITAF IL18R1 PDGFA TUBB6 PPP3CC AHNAK CASP1 MED11 OSTF1 DENND3 CCL3 NFKB1 CDKN1A COTL1 RBMS1 IRAK2 VIM HOPX ID2 CCND2 ARAP3 FCER1G EVI2A KLRD1 ARL6IP5 CD160 SGK1 TYROBP JUNB STX7 GLIPR1 DAPK2 OSM SERPINB6 CD7 TNFRSF9 DENND4A PLCG2 MFSD10 MSMO1 NKG7 PEA15 KCTD10 DUSP5 LGALS3 DOK2 GPR18 PLEKHO2 ZNF296 TSPO VASH1 SERTAD1 ELOVL1 SEMA4A TIAM1 LRP12 CYB5R4 SEC61B ITGAE HAVCR2 TRAF1 S100A4 KIT EHD4 FNBP1 PIM3 EGR1 DUSP6 SH3BGRL3 HMGCS1 CAPZB ENDOD1 CX3CR1 SLC19A2 FTL NDFIP1 MT1E CD69 CYP51A1 FXYD5	down	***
NIKOLSKY_BREAST_CANCER_16P13_AMPLICON	0.0006204	0.0075953	0.4772708	0.4113331	1.703199	93	ZG16B HBA1 HBA2 WDR90 KREMEN2 PAQR4 EME2 PKMYT1 CLDN9 CCDC78 POLR3K WDR24 SNRNP25 WFIKKN1 TELO2 MRPS34 NHLRC4 LMF1 CHTF18 NPRL3 FAHD1 RPUSD1 MRPL28 SPSB3 CAPN15 TSC2 HAGHL NME4 NUBP2 PRSS22 RHOT2 UNKL MAPK8IP3 MPG ZNF205 TBL3 MSRB1 PIGQ RAB40C AXIN1 ZNF598 RAB11FIP3 TRAF7 PDIA2 RAB26	up	**
SABATES_COLORECTAL_ADENOMA_UP	0.0009869	0.0112806	0.4550599	0.4026783	1.702955	103	CCNO CPS1 GABRP C2CD4A S100A2 GALNT6 LCN2 MUC5AC FABP6 ANLN MMP1 GRHL3 SP5 CLDN1 TRIM29 MSX2 MSX1 RRM2 SERPINA3 GPSM2 WDR72 HES6 BACE2 CXCL11 DGAT2 PSAT1 CDH3 TRIM7 LGR5 L1TD1 MMP7 ACSL6 ETV4 TNS4 CXCL1	up	*
LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER	0.0000376	0.0006913	0.5573322	0.3713808	1.702308	200	PAX9 PDCD6 CCDC127 TSFM METTL1 CDK4 NDUFS6 FIGNL1 COCH TDRKH CCT6A CLCN2 ZNF3 MAGEF1 CLPTM1L KCNH2 NUDT1 ZNF74 SDHA CCT5 NDUFS2 YKT6 MCM7 ABCC5 SETDB1 SLC12A7 EGFR PARD3 MIPOL1 CKS1B MRPL36 FASTK HDGF SEC61G TAF6 FADD DAP SRD5A1 POLR2H ILF2 ZSCAN21 DPP3 DVL3 MRPL11 DUSP12 ADAR SLC4A2 S100A13 JTB COPS6 TSTA3 PLD1 ALKBH4 PPP1R3D POLR2J BLCAP USP21 C5orf22 LANCL2 PYGO2 HAX1 PIP5K1A PSMB4 PI4KA FKBP9 MANBAL ABCF2 ARHGAP5 MRPL9 CDK5 EIF4G1 PNN SLC39A1 PI4KB NAT10 PPP1R16A CORO1B GEMIN2 POGZ INPPL1 MED15 LPCAT1 FASTKD3 OPA1 CCS PMVK PRCC	up	***
WHITFIELD_CELL_CYCLE_G2_M	0.0000622	0.0010792	0.5384341	0.3767241	1.702253	180	TRIP13 FOXM1 FGA BUB1B NEK2 CCNB1 CENPF PBK DEPDC1 TFF3 DEPDC1B TTK GTSE1 KIF14 ANLN TOMM34 PLK1 NUF2 CENPA ECT2 TPX2 CCNB2 MCM4 ASPHD2 SPDL1 HMMR CEP55 MKI67 BUB1 IDO1 AURKA VANGL1 ODF2 KIF2C C6 POC1A GPSM2 CDC42EP1 KNSTRN CKS1B HPS4 NUSAP1 BIRC5 KLHDC9 PSMG3 SPAG5 SAPCD2 SRD5A1 RANGAP1 DLGAP5 MAPK13 ANP32E KIF20B	up	**
REACTOME_BASE_EXCISION_REPAIR	0.0044964	0.0376525	0.4070179	0.4748840	1.701195	44	POLE LIG3 SMUG1 POLD2 LIG1 XRCC1 PARP1 POLE2 UNG NEIL3 FEN1 MBD4 POLD1 POLB RPA1 RFC5 PNKP PARG MPG NEIL1 APEX1 PARP2 POT1 POLD3 RFC3 POLE4 RFC4 PCNA ADPRHL2 TDG NEIL2 RPA3 POLE3 MUTYH	up	*
REACTOME_KERATINIZATION	0.0032426	0.0290153	0.4317077	0.4860781	1.700735	39	PCSK6 LIPM KRT5 PKP2 PKP1 KRT16 KRT15 FLG TGM1 PERP KRT18 ST14 PKP3 PKP4 KRT19 KRT8 SPINK5 KRTAP5-9 PRSS8	up	*
REACTOME_ACROSOME_REACTION_AND_SPERM_OOCYTE_MEMBRANE_BINDING	0.0027008	0.0251451	0.4317077	-0.9425082	-1.700181	3	IZUMO1 CD9	down	*
KEGG_VIRAL_MYOCARDITIS	0.0046669	0.0385981	0.4070179	-0.4169777	-1.699167	44	CD55 FYN CAV1 CASP9 SGCA PRF1 MYH11 HLA-DQA1 CD80 RAC2 CYCS CD86 ICAM1 ABL2 ACTB EIF4G2 MYH10 ITGAL HLA-DRB1	down	*
HENDRICKS_SMARCA4_TARGETS_DN	0.0057620	0.0451872	0.4070179	-0.4313044	-1.698824	38	PTP4A2 CYP4B1 SPRY2 CLK1 PER3 ID3 ARHGDIB HEXB HCST LTBP2 SFTPB GPR183 PTP4A1 CD74 LGALS3 CCR1 CCR6 NRP2 MAPK1 ITGB1 TREM2	down	*
REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE	0.0000177	0.0003623	0.5756103	0.3622970	1.698054	243	CEP72 CEP89 RPGRIP1L NEK2 CHCHD6 RAB3IP MKS1 TUBB2B IFT122 TTC26 CEP70 PLK1 IFT27 EXOC3 CCT2 DCTN2 HAUS5 CEP250 SMARCD3 BBS1 KIF3B FBF1 EXOC4 CCT5 ODF2 SFI1 IFT43 WDR60 IFT172 KIF3C CNGB1 C2CD3 IDH2 IQCB1 CDK1 SSBP1 CEP97 CENPJ CCT3 TCTN2 DYNLL2 SMO PRKAA2 FGFR1OP IFT52 CHCHD3 CEP63 BBS5 CEP192 NPHP1 EXOC7 TUBG1 NINL TUBB2A TUBA3D TUBA8 CNGA4 DNAJC11 NRF1 TRAF3IP1 CKAP5 WDR34 SIRT4 GBF1 TCTN1 CDK5RAP2 WDR35 SIRT5 HAUS6 DYNC2H1 ESRRA HAUS4 UNC119B CEP152 B9D1 ALMS1 CEP164 CLUAP1 TUBA4B MARK4 TCTEX1D1 TTC30B TUBA1C CLASP1 KIF24 PRKAG1 TFB1M CEP290 POLRMT DYNC1H1 PLK4 PPARGC1B AKAP9 PCNT RAB11FIP3 KIFAP3	up	***
WEST_ADRENOCORTICAL_TUMOR_UP	0.0000061	0.0001393	0.6105269	0.3586255	1.697326	273	PCSK6 FOXM1 KIF20A PARPBP FANCI ELOVL6 BUB1B NEK2 CCNB1 CENPF IGF2BP3 PBK KIF18B RACGAP1 KIF14 ASPM PTTG1 ESPL1 TPX2 GAPDH NNT MCM2 CDC25A PRC1 DTL CCT6A CAND1 XPOT ZWINT DCTN2 LSM5 BZW2 MELK NUDT1 CHAF1A BUB1 TOP2A AURKA YKT6 KIF2C MAD1L1 RRM2 RHOBTB3 CDC25C ORC6 KIF3C CAD TFCP2 SKP2 TMEM106C CDK1 RFWD3 GMNN EZH2 RALGPS1 FGFR1OP TPD52L2 DNMT1 INTS7 CCNE1 DPP3 CDC23 VPS41 TUBB2A HDAC1 DAP3 EPB41L4B TWF1 SLC1A3 ATP13A1 CENPM ACLY CDK5RAP2 CLINT1 UBE2V2 KDM4B YIPF2 LSM4 MED27 GLO1 SMARCA4 VDAC1 RFC5 WDR77 LPIN1 ZWILCH FBN2 TMED9 TARBP2 ANKMY2 SRPRB SLC36A1 PPIA ENO1 TUBA1C RAD1 PI4KB KHNYN SART3 NPTX2 COPE XPO6 DYNC1H1 ACSM3	up	***
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	0.0003704	0.0050864	0.4984931	-0.3545253	-1.697018	104	RAMP3 GPR15 LHCGR ADCY9 ADCY4 RAMP2 PDE1B CALCRL ADCYAP1R1 RXFP1 PDE4C PDE2A GNGT2 ADRB1 GNG7 ADRB2 GPBAR1 PDE4D ARRB1 PTGIR GRK5 PDE8A PDE3B GNAI2 PTH1R ADCY2 PTGER4 PTGER2 GNAI1 GNG5 GPR84 GNB4 OR52B6 HTR6 ARRB2 ADORA2A PDE4A PDE8B OR1K1	down	**
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN	0.0015126	0.0158168	0.4550599	0.4342440	1.695384	67	RACGAP1 MCM2 TYMS CCT2 LSM5 CCT5 PRKDC AIMP2 CHEK1 THYN1 TIMM50 CDK1 SSBP1 EZH2 MRPS12 EFTUD2 CDC23 C1orf131 NDUFA13 IP6K2 CHCHD1 MALSU1 LSM4 CEP152 TBCB RNF7 NMT1 CBWD1 NOMO3 NCAPD3 ZNF367 MRPL43 TEFM RFX7 KEAP1 FIBP EBNA1BP2 PSMD8 IK	up	*
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP	0.0000000	0.0000004	0.7477397	0.3389762	1.695266	579	HELLS NXPH4 AK4 PARPBP FANCI GPT2 ELOVL6 BUB1B CCNB1 CCDC34 CENPF IGF2BP3 PRTFDC1 COA1 PSPH GGCT PBK TTF2 SLC2A1 PHF14 BRCA1 PHGDH CDCA7 TTK GINS1 RACGAP1 IQGAP3 GTSE1 KIF14 ANLN CCDC14 GMPS STIL TTC26 ECT2 CDC6 SFXN1 TFDP2 NNT FIGNL1 STC2 RBBP8 MCM4 HOXB7 MCM2 TYMS PRC1 HPS3 DTL CCT6A MCM8 MIS18A ZWINT SPDL1 NME1 C5orf34 CLDN1 GFPT1 MKI67 HLTF KNTC1 CCDC77 DPY19L1 AURKA NUP155 CBX3 WDR3 ATR POLD2 YKT6 TPR KIF2C MCM7 CENPW RSRC1 PRKDC RHOBTB3 PDCD5 TMEM45A WDHD1 KISS1R ZNF146 FANCD2 GPSM2 LMNB1 TOPBP1 CHEK1 DNAJC9 ORC6 MAD2L1 RAD51AP1 RAD18 PSRC1 CKLF RBAK MIPOL1 GPX8 CKS1B NUSAP1 CBX5 MRPL37 OSMR CDK1 SSBP1 UCK2 RFWD3 ATIC NPM3 NCAPG SNAPC1 KIF2A PSAT1 STEAP3 FEN1 SSX2IP MRPS12 NLN MAD2L2 DIAPH3 LAPTM4B SRD5A1 RNASEH2A CHCHD3 HSPA4L DNMT1 INTS7 CCNE1 TUBG1 DLGAP5 NADK2 PSMA5 LMNB2 LONP1 OSBPL3 DTYMK CENPQ GINS2 LINC00662 AGPAT5 KIF20B ASNS GFM2 FKBP14 TWF1 DENND5B ENC1 SASS6 P4HA1 SUPT16H FAF1 FBXO22 ZNF780B UBE2V2 ODF2L MCM6 RAI14 CKAP2 SRPK2 XRCC4 HEATR1 SNRPD1 HAUS6 C5orf22 DYNC2H1 RCC1 CHRNA5 ATAD2 GTPBP10 KLHL7 AP2S1 SUV39H2 PMS1 CCNA2 PRR11 SHCBP1 ABCF2 WDR4 BMS1 TPGS2 ZWILCH MICU1 ACP1 WDR76 SMC2 PFDN4 DNAJC10 TRUB1 PAICS UBE2C CDKAL1 ENO1 ZC3HAV1L DNM1L ZNF367 C4orf46 PPP1R14B CALU BRIX1 IFI16 TIPRL ERLIN1 NQO1 GEMIN2	up	***
AMIT_EGF_RESPONSE_120_MCF10A	0.0060550	0.0467549	0.4070179	-0.4292906	-1.690892	38	EREG IL1A IL1B FOSL1 HBEGF EIF1 EPOR PLAUR MAFF SPRY4 DYNC1LI1 CCL20 PDLIM5 EPHA2 ING2 DUSP6 YRDC BCL10	down	*
FAELT_B_CLL_WITH_VH3_21_UP	0.0055801	0.0441368	0.4070179	0.4845281	1.690244	38	TYMS TOP3B YKT6 PKMYT1 PPP5C CNOT3 SMG5 TK1 HMGA1 CLUH VDAC1 GNA12 EIF4G1 SBNO2 UBTF SAFB TOMM40 E2F4 ZBTB48 ACTN4 SRC SMARCD1 PRKCSH	up	*
KEGG_LEISHMANIA_INFECTION	0.0024135	0.0232141	0.4317077	-0.4014996	-1.689390	53	IL1A IL1B MYD88 NCF2 TRAF6 IL10 NFKB1 TLR4 HLA-DQA1 TGFB2 JUN IFNGR1 JAK1 FOS CR1 TGFB1 TAB2 NFKBIA CYBA MAPK1 ITGB1 NCF1 HLA-DRB1 FCGR3A PTGS2	down	*
PUJANA_BREAST_CANCER_LIT_INT_NETWORK	0.0012019	0.0130364	0.4550599	0.4086517	1.689021	90	CHEK2 BUB1B CCNB1 CDK4 PLK1 RBBP8 CDC25A TP53BP1 FANCA AURKA ATR CLSPN PRKDC FANCD2 MCM3 CDC25C CHEK1 MDM2 BLM CDK1 E2F1 FANCG CCNE1 TUBG1 RAD9A HDAC1 FHL2 ESR1 RAD50 RPA1 PEX5 MSH2 CCNA2 SMARCA4 RAD51	up	*
VANTVEER_BREAST_CANCER_ESR1_DN	0.0000347	0.0006540	0.5573322	0.3603244	1.688961	242	CA9 HJURP LAD1 KCNK5 TICRR GPT2 GABRP PROM1 BAIAP2L2 UGT8 PRTFDC1 PKP1 PRIM2 PHGDH CDCA7 TTK ANLN GMPS STIL KRT16 CDCA8 CENPA GAPDH CCNB2 MYBL2 NCAPD2 LDHB PLEKHG1 MELK CEP55 KCNN4 TRIM29 BUB1 FANCA IDO1 MYO10 KIF2C RSRC1 TRPV6 PDCD5 TMEM45A RAD54L GPSM2 PLTP HEBP2 TOPBP1 PDZK1IP1 ASS1 PFKP BLM TTYH3 HDGF TNFRSF21 UCK2 C1orf112 PSAT1 STEAP3 CDH3 RAB6B ATAD3A DIAPH3 ILF2 ST14 CTSV USB1 IL15RA IFNAR2 MMP7 ASNS	up	***
VECCHI_GASTRIC_CANCER_EARLY_DN	0.0000023	0.0000573	0.6272567	-0.3034676	-1.687677	266	DAB1 SIDT2 TMEM100 SOSTDC1 ADTRP PGC FABP4 LYVE1 GREM2 CLDND1 PID1 ARRDC4 CGNL1 ST3GAL6 CITED2 MAL NR3C1 CD36 TMPRSS6 SSTR1 UBL3 MCTP1 SLC36A4 ADA LIFR C16orf89 LINC00261 GNG7 ADRB2 SFRP1 CNN1 EVI2B CYBRD1 PRDM16 C14orf132 PRKD3 KLF9 BCHE MYRIP ITIH5 GMPR AQP4 JAM2 CD302 PTGER3 VEPH1 AFF3 PDK4 TRGC2 FAM107A ID4 SYNPO2 MAGI2 NDNF RASSF10 RGS13 DUSP5 ZNF844 GABARAPL1 SCARA5 SBSPON IGKV1D-39 GPX3 SCN7A SEMA4A MFAP5 TTLL7 ALDH6A1 MT1M ZNF471 RBMS3 METTL7A GLUL KIT ABCA8 RORA NR3C2 KLF15 GHR CFL2 ZBTB16 ZNF385B ZNF677 MAMDC2 PIK3CG EBF1 MT1E LDB3 PLN SNRPN ADH1B CNTN1 CCPG1 ECHDC3 HSPB8 PLLP CYP1B1 SLC18A2 MT1X CHGA SETBP1 ZNF667-AS1 SLAMF7	down	***
BIOCARTA_BARD1_PATHWAY	0.0051985	0.0420215	0.4070179	0.7267209	1.686228	8	BRCA1 FANCA FANCD2 FANCG FANCF	up	*
REACTOME_PEPTIDE_HORMONE_METABOLISM	0.0037976	0.0326708	0.4317077	-0.3996082	-1.686153	54	FFAR4 ACE VAMP2 SPCS3 PLA2G7 ANPEP CES1 TCF7L2 KLF4 BCHE MYRIP CTSD INHBA CTSZ MME CPA3 EXOC1 EXOC2	down	*
FEVR_CTNNB1_TARGETS_DN	0.0000007	0.0000188	0.6594444	0.3396269	1.684157	476	HMGA2 TRIP13 FOXM1 SPATA24 HELLS EPHB3 KIF20A RUVBL1 CHEK2 BUB1B HBA2 ADRA2A TIMELESS PRIM2 BRCA1 PHGDH TTK GINS1 ZFP62 RACGAP1 TRAIP GMPS POLE NUF2 AURKB ECT2 CDC6 SOX9 NNT CCNB2 FIGNL1 MCM4 MCM2 TYMS PRC1 HBB NCAPD2 CDT1 CCT2 LSM5 CYP3A5 C5orf34 MELK EXO1 KIF23 KCNN4 MKI67 CARD11 KNTC1 BUB1 TOP2A CCT5 CENPL NUP155 POLD2 MCM7 CD2AP CENPW RRM2 SMYD2 RHOBTB3 ZNHIT6 RAD54L MRPL3 MCM3 CHAF1B CDC25C SOX4 SMYD5 EGFR LIG1 CHEK1 ORC6 FBL CENPO PFKP RAD51AP1 DSCC1 EHF EEFSEC SKP2 GEMIN4 INCENP KNSTRN CBX5 ASF1B ANAPC5 CDK1 HDGF POLE2 KCNE3 CENPH BIRC5 CCT3 AAGAB E2F1 UNG GJB3 GNPNAT1 ENPP3 FEN1 EZH2 SPAG5 LIPT2 MTBP CBX1 DIAPH3 CENPP PA2G4 DNMT1 VBP1 NINL NMRAL1 KIF22 EPHB2 TRIM37 SSRP1 DTYMK CHTF18 MSI2 POLD1 POLB CDC7 CENPK CDC20 KIAA0100 AHCYL1 LIPG FAM136A RPA1 MCM6 CKAP2 MCM5 CAPRIN2 SNRPD1 HAUS6 ADD3 SRSF1 CUBN LRIG1 GTPBP10 NUP62 PMS1 MSH2 CCNA2 PRIM1 SHCBP1 RAD51 TRIP6 ARHGAP5 SCOC ERGIC1 ACP1 SLC12A2 POLR1B CENPE SMPD4 MTHFD1 PAICS FGFBP1 APEX1 TTC30B EPHB4 PNN NUP210 RAD1 RRS1	up	***
KEGG_ADHERENS_JUNCTION	0.0029385	0.0267270	0.4317077	-0.3877982	-1.679707	61	PTPRB FYN BAIAP2 CDC42 TGFBR2 RHOA PTPRM NLK TCF7L2 SNAI1 SORBS1 TJP1 WASF3 WASF2 RAC2 ACTN2 CSNK2A2 TCF7L1 SMAD2 ACTB CREBBP FGFR1 IQGAP1 SMAD4 MAPK1 LMO7 EP300	down	*
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN	0.0000001	0.0000026	0.7049757	-0.2868080	-1.678803	413	DENND5A GLIPR2 ZC3H12C ENG BDNF HSD17B11 CD44 PPP4R1 CCDC88A BACH1 ST3GAL6 CAV1 CORO1C FOSL1 QKI NR3C1 TGFBR2 RFTN1 HEG1 ANXA1 EIF4A1 SH2B3 ASAP1 PTPRM B3GNT5 TTL EMILIN2 ECHDC1 ZDHHC2 PICALM ANXA5 LUZP1 RNF182 GLS PRSS12 CAV2 PTX3 NDEL1 SLC25A37 SFRP1 AKT3 SPTBN1 SPRY2 KANK2 ZEB1 SRGN PDGFA TUBB6 ZYG11B EPB41L2 FLI1 ITPRIP CCDC82 SGTB SDCBP CASP1 ZCCHC24 PRKD3 DAB2 BCHE GRK5 ABCC4 SPAG9 MARVELD1 CXCL2 IRAK2 VIM AXL LBH ARAP3 ELK3 INHBA DSE IL7R UBASH3B CYP26B1 PAFAH1B1 CRIM1 CNRIP1 ACTR2 TGFB2 EMP3 FMNL2 IL6 SGK1 SOCS3 MAML2 RAB8B PNMA2 RAB31 KCTD12 LTBP2 ETS1 HRH1 MSRB3 MAP4K4 CCDC50 ELP5 GLIPR1 PABPC4 MALT1 NOL7 GFPT2 MCAM AGPS NAP1L5 FLNC TIMP2 TGFB1 SERPINB1 MTMR2 TGFB1I1 CTNNAL1 GNAI1 NAB1 PIM1	down	***
REACTOME_SODIUM_PROTON_EXCHANGERS	0.0062921	0.0482684	0.4070179	0.8028654	1.677847	6	SLC9A3 SLC9A2 SLC9A5 SLC9A9	up	*
CAIRO_HEPATOBLASTOMA_CLASSES_DN	0.0000793	0.0013431	0.5384341	-0.3150618	-1.676909	179	LIMS2 RAMP3 WFDC1 CAT LPXN HSD17B6 PTPRB ENG SLC10A1 EMCN GFOD1 KANK3 LDB2 AQP9 ALAS1 GAS6 DNASE1L3 PDE2A MMRN2 ABHD6 SPTBN1 KANK2 ZEB1 ATP10A SNED1 SYNPO ZCCHC24 TJP1 MYRIP ITIH5 NR1D2 SMAD7 ADIPOR2 ARL6IP5 FRY KLRB1 IL2RB FAM189A2 RCAN1 SNRK RRAS HIVEP2 PEA15 TSC22D1 AOX1 CD81 GABARAPL1 LMOD1 PAMR1 CDC42EP3 GIMAP5 ALDH2 DAPK1 GLUL NFKBIA KLRK1 GPR171 MAN1C1 PHYH EGR1 GHR DKK3 CX3CR1 PRKCH	down	**
COATES_MACROPHAGE_M1_VS_M2_UP	0.0028471	0.0260246	0.4317077	-0.3657926	-1.675823	78	RASAL2 P2RY13 MARCO TXNIP ADA MALAT1 SLC7A7 FAM124A ARSB MSR1 HAUS2 PLBD1 CADM1 AXL PTGER3 PPP2R5C HLA-DQA1 CRIM1 CNRIP1 SLCO2B1 CAP1 OGFRL1 BLOC1S6 PIK3AP1 GNB4 ACYP2	down	*
LEE_DIFFERENTIATING_T_LYMPHOCYTE	0.0000548	0.0009631	0.5573322	-0.3170795	-1.674902	174	CD52 KLF13 LPXN SRSF7 MAL ATF7IP2 TXNIP EIF4A1 BTG2 PAG1 GATA3 RGCC FLI1 EVI2B HAUS2 MGAT4A LAPTM5 PTPRC SELL ARHGAP9 CD53 EVI2A IL7R CNOT6L ARHGDIB BTG1 NCKAP1L TRGC2 RYBP AQP3 CD48 GIMAP2 RAC2 GMFG DOCK8 CELF2 OCIAD1 ICAM2 SRSF6 ING3 CCDC152 TAGAP MR1 SELPLG LAT TNFAIP8 CXCR4 CD3G CYTH1 FGFR1 CCND3 SFPQ SPATA13 FNBP1 LNPEP PRKCH ICOS ITGAL KMT2E PIK3CG RCSD1 STX16 ATP8A1 TRAT1 AKAP13 ARHGAP30 FAM107B RASSF5 PNISR TMEM71 CBX4 ITK DOCK2 HCLS1 CD3D BCL2L11 APBB1IP METAP2 SNX20	down	***
REACTOME_CD22_MEDIATED_BCR_REGULATION	0.0042959	0.0362029	0.4070179	0.4638881	1.674236	46	IGLV3-27 IGKV1-17 IGKV3-15 IGKV3-11 IGKV1-16 IGKV4-1 IGKV2D-28 IGLV1-44 IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGLV7-43 IGLV6-57 IGHM IGLV1-47	up	*
GOLDRATH_IMMUNE_MEMORY	0.0026453	0.0248375	0.4317077	-0.3864129	-1.672838	60	CD55 CTSW AQP9 ABCB1 PRSS12 CYP4V2 SORBS1 RRM2B PDE8A DOCK9 NR1D2 RECK PLCD1 CD160 KCTD12 PRKCE RRAS CHPT1 FCGRT RNF138 TRAF1 PALD1 CHCHD7 MCOLN2 USP48 HCFC1R1	down	*
DANG_REGULATED_BY_MYC_DN	0.0000331	0.0006281	0.5573322	-0.3061735	-1.671319	211	ACP5 HMOX1 TMEM126A BDNF CAV1 LAMP1 SLC11A1 TGFBR2 JPH2 MAN2B1 HBEGF GM2A HSPB1 RB1 SDCBP CASP1 LIMS1 KLF4 PLAUR ITM2B RRM2B ID3 ROCK1 GAA THBS1 CEBPA KLF7 MYO1B CDKN1A CTBS ID2 DUSP1 INHBA WFS1 FOXN3 MYO1C VAMP3 MAGI2 CD48 PPP1R15A SP3 DDX5 DLEU2 ACSL1 CD151 HIVEP2 MYL12A TIMP2 TGFB1 PEA15 SERPINB1 PIM1 CSDE1 FCGRT SERINC3 TSPO CCNH SCPEP1 ISCU EDN1 PAK2 RAB2A PMAIP1 LYZ HNRNPH1 UBE2V1 CHP1 SERPINE1 CDKN1B DUSP6 ITGAL ITGB1 FTL	down	***
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN	0.0000138	0.0002911	0.5933255	0.3469932	1.669508	312	LINC00342 BUB1B GGCT SORD TTK CDK4 RACGAP1 E2F8 GMPS PTTG1 ECT2 GPI GAPDH CCNB2 MCM4 SLC35E3 MCM2 TYMS CDC25A PRC1 DTL CCT6A MIS18A SHMT2 ZWINT MRPS35 COX11 LSM5 NME1 LDHB BZW2 MELK HMMR NUDT1 CEP55 KIF15 PCCB WASF1 TOP2A RRM2 PRKDC MRPL3 KIF11 KDELR2 CHEK1 MAD2L1 AHCY FBL RAB13 RAD51AP1 ETFA IDH2 CNPY2 DYRK2 CKS1B HPS4 NUSAP1 CDK1 SSBP1 POLE2 BIRC5 CCT3 ATIC GMNN GOT2 UNG NCAPG SNRPE LAPTM4B CHCHD3 ATP9A SPTSSA SSRP1 GINS2 ANP32E MARCKSL1 COPS6 CCT7 STOML2 IARS2 AHCYL1 HMGA1 RPA1 MCM6 MYO5C MRPS33 TBCA PRMT1 MCM5 NEK4 LRIG1 CCNG1 HAUS4 LSM4 DPH5 INTS8 GLO1 PRIM1 VDAC1 SNRPD2 SHCBP1 RAD51 TPGS2 PFKM OXCT1 NDUFA8 SMC2 MTHFD1 PAICS GPX7 APEX1 PPIA ENO1 TUBA1C LXN	up	***
KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN	0.0063679	0.0486944	0.4070179	0.7194693	1.669402	8	CCNB1 CENPF KIF2C SPAG5 CDC20 CCNA2	up	*
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY	0.0034769	0.0306647	0.4317077	-0.3715236	-1.668796	67	CD22 NFATC3 LILRB3 PPP3CA AKT3 PPP3CC NFKB1 PIK3R5 JUN RAC2 PIK3R1 GRB2 MALT1 PLCG2 FOS PIK3AP1 VAV3 PPP3R1 CD81 CD19 NFKBIA CHP1 MAPK1 PIK3CG CD79B DAPP1 BCL10 SOS2 RASGRP3 PIK3R3 NRAS	down	*
PUJANA_CHEK2_PCC_NETWORK	0.0000000	0.0000002	0.7614608	0.3318102	1.668132	675	TRIP13 FOXM1 BIK MYBPH RUVBL1 CDC45 FANCI TROAP CHEK2 BUB1B CCNB1 CENPF TIMELESS CPSF6 TTF2 NDC80 TTC39A BRCA1 BET1 TTK GINS1 CDK4 GTSE1 KIF14 GMPS POLE STIL PLK1 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 TFDP2 CCNB2 NBR2 RBBP8 MCM4 MCM2 TYMS XPNPEP1 MYBL2 CCNF SHMT2 NCAPD2 ZWINT CDT1 COX11 CCT2 LSM5 NME1 LDHB RANBP1 CASP2 MELK HMMR EXO1 NUDT1 SMARCC1 CHAF1A LAMC2 MKI67 KNTC1 PAFAH1B3 BUB1 EEF1E1 TOP2A IDO1 CCT5 AURKA CBX3 ATR KIF2C MCM7 CD2AP MPHOSPH9 RRM2 PRKDC WDHD1 RAD54L MRPL3 KIF11 MCM3 LMNB1 RNFT2 LIG1 POLR3C TOPBP1 CHEK1 DNAJC9 ACTL6A MAD2L1 FBL RAD51AP1 CAD ETFA BLM CNOT3 MNAT1 MYO1A PARP1 THOP1 CKS1B CDKN2C TMEM106C ANAPC5 CDK1 HDGF SSBP1 POLE2 SNX4 UCK2 CCT3 ATIC GTF2E1 RBCK1 NPM3 UNG TCF20 DNA2 SEC61G FEN1 EZH2 NUP205 SPAG5 NF1 TTI1 SNRPE NOP2 RECQL4 PA2G4 RNASEH2A POLR2H DNMT1 VBP1 PELP1 ILF2 TRIM24 CDC23 GNPAT DLGAP5 PSMA5 ADNP AGL SNRPA LMNB2 RAD9A PSME2 HIRA HMGN3 SSRP1 DPH2 DTYMK HDAC1 TP53TG1 ANP32E TCEA1 KIF20B TM9SF4 ELAC2 CDC7 ABCC10 PFAS CPSF4 KLHL23 CDC20 IARS2 PPP1R8 ACLY RPA1 POLR2J MCM6 TBCA MED24 PRMT1 UTP20 MCM5 LSM7 TFAP4 SRSF1 AATF RCC1 LSM4 PSMB4 TXNL4A CHRNA5 TSR1 TCERG1 NUP62 PMS2P1 MSH2 CCNA2 SMARCA4 ZNF195 SNRPD2 RFC5 WDR77 HK2 ARHGAP11A SRP9 PAXIP1 SNRNP200 UBAP2L ZNF131 SMC2 PARG CENPE TCF3 PFDN4 DDX52 POP4 SMPD4 NMT1 SEPHS1 PAICS CHERP SNRPC PPIA UBE2C PNN TAF4 GPN1 PWP1 RIMS1 NUP210 RAD1 SMARCB1 RRS1 ZNF337 SART3 ERCC3 GEMIN2 PARP2 LYPLA1	up	***
VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP	0.0042260	0.0358399	0.4070179	0.4368782	1.667479	60	TSPAN8 TF HKDC1 EGLN3 PKP2 LSR SHMT2 TNNT2 AP1M2 FAM162A SLC9A3R1 SPINT1 ALDOA SLC39A5 KCNE3 REEP6 ALDOB CTSV SLC13A4 KRT19 CCNG1 PRSS8 ADM CDH1	up	*
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN	0.0000002	0.0000066	0.6901325	-0.2858359	-1.666746	388	CXCL3 SLPI EREG IL1A ZC3H12C MIR22HG HSD17B11 CD44 PPP4R1 CCDC88A GFOD1 ST3GAL6 CAV1 CORO1C FOSL1 CYB5R3 NR3C1 TGFBR2 RBM7 ANXA1 BMP1 PTPRM B3GNT5 ADA CHMP1B GM2A ZDHHC2 LUZP1 PRSS12 CAV2 CAMTA1 SIRPA RGCC ADRB2 NFE2L2 NDEL1 SLC25A37 CRK SFRP1 AKT3 SPTBN1 SPRY2 SOX7 BTG3 TUBB6 CD58 CYBRD1 TLE4 CCDC82 CASP1 YBX3 PXDC1 PRKD3 TMED5 MYO1B CLIC4 COTL1 RBMS1 CXCL2 AXL LBH ARAP3 ELK3 INHBA DSE CLIP4 IL7R UBASH3B ANXA3 EMP3 ETF1 FMNL2 VAMP3 YBX1 SGK1 MAML2 STAT4 ETS1 HRH1 RAC2 OSBPL9 MAP4K4 DUOX1 IFNGR1 GLIPR1 MBNL2 NUDT15 OGFRL1 RALB AGPS MBP RUNX3 MYL12A MME MTMR2 GNAI1 NAB1 IRS2 RGS2 CSNK2A2 ETS2 MBNL1 GTF2B AMD1 ICAM1 FGF2 IL18 TNFAIP8 ARPC2 FKBP1A WDR1 CDC42EP3 CEBPD ORMDL1 TBC1D1 SP100 EPHA2 SCPEP1 SOAT1 RBMS3 COPS8 CTSC FDFT1 KIF1B NABP1 MT2A TOX2 TNFRSF10D CFL2 ZBTB16 TBPL1 TMEM30A SVIL GJC1 ITGB1 CMPK1 SH3GLB1 HP1BP3 CD109	down	***
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN	0.0002635	0.0037588	0.4984931	0.3743619	1.666534	162	FOXM1 MCM10 PROM1 CCNB1 POLE PTTG1 PAK6 CDC6 TPX2 NNT CCNB2 MCM4 MCM2 TYMS CCNF RANBP1 WDR62 HMMR EXO1 KIF23 CHAF1A MKI67 WASF1 KIF2C RRM2 RHOBTB3 CDC25C SIDT1 CHEK1 MAD2L1 INPP4B IDH2 CKS1B CDKN2C TMEM106C POLE2 BIRC5 TESC MECR SRD5A1 TUBG1 DLGAP5 HMGN3 TK1 DTYMK RHD POLD1 CDC20 CENPM RPA1 CORO2A CCNA2 SHCBP1 BLVRB INSL3 TRIB2 MTHFD1 DHRS3 GPX7 UBE2C NUP210 HGF NCAPH CD38	up	**
REACTOME_SIGNALING_BY_TGF_BETA_FAMILY_MEMBERS	0.0011453	0.0126714	0.4550599	-0.3522237	-1.665991	94	SMAD6 ACVRL1 GREM2 BMP2 NEDD4L BMPR2 CBL TGFBR2 RHOA ZFYVE16 UBE2D3 CDK9 SMAD7 INHBA JUNB PPP1R15A SKIL FSTL3 UBB TGFB1 PARD6A TGIF1 ZFYVE9 SMAD2 FKBP1A UBE2D1 SKI SMAD4 PPP1CB ARHGEF18 ACVR1C SERPINE1 CCNK NOG SNW1 CCNT2	down	*
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	0.0002942	0.0041542	0.4984931	0.3730257	1.663429	164	BUB1B NUP107 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 CDCA5 MAD2L1 PSMD4 CENPO SPC24 INCENP ANAPC5 CENPH BIRC5 PSMB5 KIF2A ANAPC7 DYNLL2 PSMC4 CENPP RANGAP1 CDC23 PSMA5 TUBB2A PSME2 TUBA3D TUBA8 CENPQ ANAPC1 PSMD2 NUP85 CENPK CKAP5 PSMB3 CDC20 CENPM DYNC1LI2 CENPT	up	**
PID_FAK_PATHWAY	0.0036518	0.0319016	0.4317077	-0.3929342	-1.663415	56	FYN ELMO1 RHOA ASAP1 RAP1A ITGA5 CRK ROCK2 PTPN21 JUN ETS1 RAPGEF1 PIK3R1 GRB2 RRAS MAPK8	down	*
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN	0.0019752	0.0196130	0.4317077	0.4168536	1.663082	74	ATP6V0A4 ALDH3B2 GPR87 TP63 EPN3 PROM1 DNAJC12 TTC39A SLC27A2 STC2 TJP3 HOOK1 MDK PDZK1IP1 TBC1D8 PERP MRPS30 GRB14	up	*
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	0.0000000	0.0000000	0.9214260	0.3244974	1.659119	1128	SLC9A3 TRIP13 GRIK2 FOXM1 HELLS HJURP PKP2 RUVBL1 CDC45 TICRR PARPBP MCM10 FANCI TROAP CHEK2 BUB1B SYNPR PROM1 NEK2 COIL TRNP1 CCNB1 DNAJC12 CCDC34 SOX2 CENPF TIMELESS POLQ UBE2T MPP6 MND1 KIF18B PKP1 TTF2 CLGN NDC80 RAB3IP PRIM2 DEPDC1 SLC25A21 SORD BRCA1 DEPDC1B CDCA7 C12orf66 ZNF138 TTK GINS1 CDCA2 RACGAP1 IQGAP3 E2F8 GTSE1 KIF14 NOL12 ANLN AC011043.1 ASPM PLK1 NUF2 YEATS4 KCNQ5 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 TRIB3 FIGNL1 UHRF1 MCM4 MCM2 RAD54B TYMS XPNPEP1 CDC25A UMPS MYBL2 PRC1 ORC1 CCNF PLS1 DTL DYNC1I1 MCM8 XPO5 KIAA0895 GINS4 NCAPD2 ZWINT CDT1 ZNF107 CCT2 SPDL1 TAMM41 FAM220A RANBP1 CLDN1 MELK HMMR EXO1 C19orf48 SMARCC1 XPNPEP3 KIF23 CEP55 CHAF1A GFPT1 PAQR4 MKI67 ZNF850 HLTF EMC9 KIF15 MRPL15 FBXO43 KNTC1 RHNO1 BUB1 FANCA AUNIP TOP2A IDO1 CENPL PUS7 BPHL AURKA EME1 NUP155 C1orf226 POLA2 SAE1 ATR KIF2C MCM7 E2F2 POC1A MPHOSPH9 CPD RRM2 CDCA5 PRKDC WDHD1 HOOK1 RAD54L DCDC2 KIF11 PASK FANCD2 GPSM2 MCM3 CHAF1B LMNB1 CDC25C FAM162A LIG1 BRI3BP POLR3C KDELR2 CHEK1 DNAJC9 ORC6 MAD2L1 CKAP2L TRMT61B NFYA CENPO PFKP RAD51AP1 DCTPP1 PRMT6 PKMYT1 BRIP1 ZNF507 RAD18 BLM PPP5C GLE1 CCDC138 DBNDD1 COQ9 SKP2 PARP1 GEMIN4 INCENP THOP1 KNSTRN NCAPG2 CMAS FRMD5 NUSAP1 URI1 ASF1B CDK1 POLE2 KCNE3 EXOSC2 CENPJ DIDO1 UCK2 BCAS4 RFWD3 CENPH BIRC5 ESRP1 ABHD17C C1orf112 GMNN NBPF3 POC5 E2F1 NCAPG STX18 STEAP1 DNA2 KIF2A DHX33 PSAT1 FSBP NEIL3 FEN1 SSX2IP NUP205 POC1B SLC35F3 ATAD3A ITPR3 PA2G4 RNASEH2A KPNB1 RANGAP1 NET1 MYO19 SLAIN1 DNMT1 FANCG EDEM3 TUBG1 DLGAP5 GALK2 TRMU PUS1 TACC3 SNRPA MBD4 TUBB2A OSBPL3 NGFR SLC37A4 UBE3D SUDS3 SSRP1 TMEM237 TK1 DTYMK MYBBP1A GINS2 GEMIN5 ANP32E PKP4 TCEA1 KIF20B SRD5A3 ASNS GFM2 TSEN54 CDK13 NUP85 ITGB2-AS1 CCZ1 SCNN1G SLC1A3 ATAD5 ELAC2 CDC7 EFCAB7 CENPV CKAP5 KLHL23 CDC20 CENPM PPP1R8 FBXO22 ACLY ZNF76 RPA1 ENTPD3 CDR2 ASRGL1 UBE2V2 MCM6 MGME1 CKAP2 SRPK2 DHX8 MCM5 USP21 ZRANB3 SNRPD1 MAB21L3 HAUS6 NEK4 FAM161A SLC35A3 SRSF1 C1orf109 GINS3 AATF DUS4L PIGX RCC1 HAUS4 SLC1A5 LSM4 WDYHV1 ATAD2 TSR1 CEP152 DUS2 NUP62 CEP85 SUV39H2 MSH2 ME1 RCN3 PRIM1 PRR11 ZNF93 DDX54 RFC5 TUBGCP4 USP39 ABCF2 WDR4 AP001372.2 HK2 RAD51 FARSB ZWILCH	up	***
REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC	0.0001600	0.0024396	0.5188481	0.3647176	1.657137	185	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 RAB36 DYNC1I1 COPB2 KIF27 DCTN2 KIF23 BICD1 KIF15 COPG2 COPG1 PAFAH1B3 KIF3B YKT6 KIF2C RHOBTB3 KIF11 KDELR2 KIF3C TMED3 NSF KIF5A STX18 KIF19 KIF2A DYNLL2 RAB6B GOLGA5 ARFRP1 TUBB2A TUBA3D COG2 COG7 KIF22 ARF5 TUBA8 KIF21A KIF20B COG4 KLC2 KLC4 KDELR3 COG1 GBF1 MAN2A1 DYNC1LI2 KIF21B RABEPK VPS53 GOSR2 COPZ1 ARFGAP1 COG5 CYTH2 TUBA4B COPA SCOC TMED9 RAB43 GOSR1 CENPE COPZ2 TUBA1C PLIN3 COPE DYNC1H1 CYTH3 GCC2 KIFAP3 GCC1 COG6 ARFIP2 KIF6 ARL1 BNIP1 NBAS KIF3A DCTN3 RGP1 MAN1A2 KIF13B STX10 DCTN5	up	**
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN	0.0000004	0.0000124	0.6749629	-0.2897284	-1.656327	360	EPAS1 SIDT2 SWAP70 ABHD5 TSPAN4 PDLIM2 CAT ENG BDNF TMOD3 CAV1 GAS6 LAMP1 EOGT TGFBR2 RFTN1 SCARA3 RHOA AVPI1 ANXA1 BMP1 RRAGC ASAP1 ITGA5 ANXA5 KLF6 CAV2 PTX3 NDEL1 GRN CST3 ATP10A MTMR6 SCP2 PLAUR PXDC1 COQ10B ID3 DAB2 DRAM1 THBS1 TMED5 TPP1 MYO1B CLIC4 SPAG9 SSH1 PAPSS1 AXL LBH PLEKHB2 DUSP1 ELK3 SMAD7 INHBA SLC25A32 GNAI2 BACE1 CMTM6 ACTR2 HEXB TMEM9B VAMP3 NSMAF SNAP23 VAT1 RAB31 OSTM1 JAK1 GSTO1 SNX2 STX7 GLIPR1 HSPA13 IDS CAP1 FSTL3 TAGLN2 NDST1 CD151 GRSF1 ATP6V0D1 RRAS KLF2 ATG3 PKD2 XYLT1 TIMP2 TGFB1 EHD1 PEA15 TGFB1I1 CD81 APLP2 NQO2 GABARAPL1 STX12 NPTN ADAM10 TSPO MBNL1 PITPNA FGF2 PDLIM5 WDR1 ELOVL1 SEC61B SCPEP1 TMEM184B PARVA ARPC5 PTEN NRG1 IQGAP1 PSMD9 CNN2 FEZ1 PAPSS2 SPHK1 TMEM50A CLIP1 SH3BGRL3 TMEM43 CAPZB ENDOD1	down	***
NAKAMURA_ADIPOGENESIS_LATE_UP	0.0019291	0.0191904	0.4550599	-0.3499762	-1.653836	91	PPARG FABP4 INSIG1 CCRL2 MYADM CDH13 TGFBR3 GAS6 CD36 GM2A SERPINB9 STOM CYBRD1 FOXO1 STX3 ZNF24 SIK2 ATF3 ELK3 PPP2R5A TGFB2 RAB31 CCDC50 PLK3 XYLT1 TGFB1 IRS2 RAB5A CEBPD ACACB MMD SMPD1 USP4 HMGCS1 MAPK1	down	*
PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP	0.0058575	0.0456767	0.4070179	0.4356614	1.652430	59	COPB2 GOLPH3L COPG2 COPG1 KDELR2 PSMD4 CBY1 PSMC4 PSMA5 ASNS SIL1 PSMD2 GOLM1 PSMB3 PRSS16 PDIA4 PSMB4 ERGIC3 GOSR2 COPZ1 COPA ERGIC1 TMED9 TBCB TRAPPC6A COPE	up	*
REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	0.0042965	0.0362029	0.4070179	0.4277258	1.649893	62	IGLV3-27 IGKV1-17 IGKV3-15 IGKV3-11 IGKV1-16 IGKV4-1 IGKV2D-28 IGLV1-44 IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGHG1 PLCG1 IGLV7-43 ITPR3 IGLV6-57 IGLV1-47 PLD1 AHCYL1 IGKV1D-12	up	*
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP	0.0000181	0.0003699	0.5756103	0.3406769	1.649459	327	KIF12 PRLR ONECUT2 ZDHHC8P1 EPN3 DEPTOR GALNT6 ZNF84 ZNF12 IQCE PRRT2 TTC39A PLEKHH1 SPDEF TFF3 CREB3L4 BCAS1 POLE C4orf19 AGR2 CA12 EIF3B AVL9 ASTN2 SLC4A8 EPS8L1 TJP3 RSPH1 ZNF74 FOXA1 FRS2 TMEM184A SLC2A10 SYNE4 P4HTM SYCP2 SFI1 ICA1 SBK1 MCCC2 SIDT1 SLC9A3R1 KDELR2 CSRNP2 RABEP2 C7orf26 DHRS13 RBAK PRRT3 TTC9 KIAA0556 CTXN1 KLHDC9 NEK5 TTC6 USP42 RALGPS1 TNRC18 MYO5B VPS72 KLHL22 ACVR1B DENND1A LZTR1 ULK1 SNX27 ATP6V0E2 LLGL2 GPRC5C C9orf152 HIP1R HID1 PKP4 KRT19 ESR1 BAZ2A GTF3C1 ERBB3 SH3GLB2 KDM4B ZSWIM8 ANXA9 CACNB3 SCYL3 TBC1D30 RAB3D TBC1D16 MYEF2 PI4KA SMARCC2 TC2N PATZ1 STRBP PYCR1 ATP6AP1 CANT1 HK2 TRAPPC9 SLC25A29 RSAD1 ERGIC1 SOX12 NDUFS8 ADCY6 CAMSAP3 RHPN1 CAPN9 CISH PPP1R16A PRKAG1 ANKRD13D POGZ CYHR1 LONRF2 ATXN7L3B LUC7L3 SLC38A10 LRRN1 RAB40C RUSC1 TMEM229B TRPS1 GGA1 RAB11FIP3	up	***
ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN	0.0047475	0.0390040	0.4070179	0.4167669	1.648002	71	TOX3 CDCA2 SLC26A8 ENAM SPATS2 SCG5 GFPT1 KIF15 MMS22L CCL28 SLC28A2 NCAPG2 NUSAP1 NSF POLE2 AAGAB SLC12A8 ANXA2R SLC26A2 TMEM237 KIF20B CEP128 IQUB UTP20 ZNF563 CFH USP39 TRAPPC9 RAB25 KDM5B TPM1 MBTD1 ST6GALNAC1	up	*
OSMAN_BLADDER_CANCER_UP	0.0000002	0.0000055	0.6901325	-0.2870381	-1.647891	370	MS4A7 PTP4A2 COQ2 CD44 TMOD3 SAMHD1 KIAA1109 CITED2 INPP5A USP47 ACER3 DNAJB14 SNHG5 MALAT1 SGMS2 EIF5 MED19 LAIR1 C1orf162 SLC25A37 ZFYVE16 SPI1 TCF7L2 RAB14 ZYG11B CDADC1 AGO3 LRRC57 SCP2 LIN7C VASP TMED5 CEBPA SOCS2 ATP6V1D TPP1 CTSD SSH1 RBMS1 PTPRC CEP57 ACTR3 PRF1 FCER1G CCSER2 SMAD7 BCLAF1 KPNA3 USP16 PIAS1 NCKAP1L ELF1 PHACTR2 APPL1 HCFC2 SF3B1 CD48 KCTD12 DESI2 GLUD1 FOXN2 ENPP4 PIK3R1 HSPA13 PTGER2 TRAK2 DLEU2 MOB1A BLOC1S6 RHOQ AGPS KLF2 AZI2 TNFSF13 RUNX3 ALDH3B1 NKG7 TGFB1 STRN KHDRBS1 EWSR1 MAP3K2 ATXN1 TMEM107 LGALS3 KYNU SERINC3 MR1 MBNL1 INO80D INTS6 PDLIM5 CHURC1 NBN SRP72 MS4A4A HSP90AA1 THAP6 RIPK2 ARIH1 ALDH2 HAVCR2 MEX3C PSME4 STK4 CTSC ZDHHC5 LYST CCND3 IQGAP1 RNH1 SUGT1 CRTAP SPPL2A SVIL ATP11B UBA6 LNPEP TGOLN2 FAR1 CALR SRSF11 BSG WDR41 UBE2W NOL9 IER3IP1 RMDN1 SCAF11 SLC25A40 ACTR1A RAD21 CRIPT RNU6-1016P KLHL9 NKTR SECISBP2 FNIP1 APOBEC3C IMPACT AKAP13 NFKBIZ CYP1B1 BICD2 FAM107B ZC3H7A C3AR1 CPNE3 PNISR LDLRAD3 SRP19 JAZF1 MTDH SCAMP1 RASA2 ANKRD17 CD47 SNRNP48 PTPN22	down	***
CHEN_METABOLIC_SYNDROM_NETWORK	0.0000000	0.0000000	0.9214260	-0.2588726	-1.646841	1036	AJAP1 SEMA3G CXCL3 CLEC1B NLRC4 SLPI ACVRL1 MS4A7 CXCL16 OLR1 ACE ASGR1 TMEM52B ADPRH SCIMP USP12 PPARG HVCN1 MNDA LPXN GPR65 PTPRE BMPER LIPA TRPV2 LYL1 LPL EGR2 CD44 LY86 LMO2 ECSCR CCRL2 SAMHD1 BACH1 MYADM EML1 CLEC10A SLC15A3 P2RY13 CDC42 CASP12 MANBA NEDD9 IL1RL1 BCL2A1 NCF2 CD9 SLCO2A1 AGPAT4 FRAT1 CD22 SLC11A1 EPB41L3 TGFBR2 IGSF6 PILRA ACER3 SIGLEC6 SEMA6D CD36 DPEP2 ARHGAP10 PLA2G7 LACTB MAN2B1 SEMA3B LMNA ASAH1 ENTPD1 CLEC7A TNIP3 MAP3K8 IFI30 ZNF503 PICALM ANXA5 LITAF ABCG1 FOXP1 ANPEP BFAR TREH LCP1 SERPINB9 LAIR1 SIRPA NFE2L2 GRN CES1 TFEC SRGN SPI1 BTG3 ARL11 MCL1 TUBB6 CD37 ATP6V1B2 EPB41L2 MSR1 KIF1C TBC1D9 SYNPO PTGIR TLE4 PTPRO MEFV MPEG1 NOSTRIN CASP1 BST1 MED11 PLAUR UBTD1 AIRN FUT7 SLC7A8 OSTF1 DRAM1 STK17B FAM49B ABCC4 CTSD FMNL3 CCL3 LAPTM5 COTL1 CADM1 PDE3B ITGAX PTPRC ATF3 VIM ATP6V0D2 TLR4 IGFBP2 ARHGAP9 FRMD4A ACTR3 TM6SF1 PLEKHB2 SS18L2 CD53 FCER1G ALOX5AP PLEK EVI2A DSE MATN2 WFS1 SLC6A6 UBASH3B HLA-DQA1 ANXA3 TANC1 PI4K2A CNRIP1 RASGEF1B ARHGDIB MMP19 GLB1 SNN STK24 HEXB LACC1 MTPN CLN8 NRROS NCKAP1L NINJ1 EMP3 RPS6KA2 PRCP MCMBP SLC8A1 RNF149 CD160 CTSS SLCO2B1 RAB8B OASL RGS18 HCST SLC35E4 CD48 JUN HPGDS CCDC3 VAT1 STAT4 RAB31 GAS2L1 LTBP2 HK3 HIC1 RAC2 ST6GALNAC4 ATP6V0B TYROBP IFNGR1 RHOJ AK1 STX7 GLIPR1 CD83 IRF8 GMFG PTGER2 SERPINB6 SNX1 LPCAT2 DOCK8 APH1B TAGLN2 WDFY4 CD34 PLCG2 FOS SLC25A24 NECAB1 ECI2 EHD2 ALDH3B1 TREX1 MYL12A CD74 RIN2 PIK3AP1 C19orf38 IRF5 SORT1 AZIN1 ZNF521 STXBP3 GSAP PEA15 DOK3 MILR1 DCK KCTD10 VAMP4 TEC NLRP6 CYGB DUSP5 TGFB1I1 ATP6V1A IFNAR1 KCNN2 CD86 MPV17L LGALS3 DOK2 LRCOL1 PHF11 GATA6 RGS2 LTBP1 ME2 MLANA UNC13D SESN1 ABL2 TNFAIP8 ARPC2 FKBP1A CTTNBP2NL SLC31A1 WDR1 TXNDC15 OPN3 CALHM2 ALDH1B1 ELOVL1 ARRB2 IER5 MS4A4A PIP4K2A LRP12 ARHGAP18 TBC1D1 SP100 HAVCR2 FBXO25 POLR2M SCPEP1 SOAT1 RBMS3 PLGRKT RASSF8 TTC28 ABI3 DOCK10 ARPC5 GNMT CHCHD7 LTBP3 MCOLN2 SAMSN1 THEMIS2 NRP2 NRG1 CREG1 ZFAND2A EHD4 RNH1 RAB2A ANO6 MAN1C1 PMAIP1 LYZ SPHK1 ZFYVE26 MAP4 CYBA ATP6V0A1 PHYH HTRA2 CSF2RB C1QB CTSH CNR2 TBPL1 SH3BGRL3 FADS3 FAM131B TMEM43 FKBP1B ZNF385B ENDOD1 C5 PIP5KL1	down	***
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL	0.0000826	0.0013900	0.5384341	0.3460079	1.644333	278	BBOX1 FOXM1 HS3ST1 MCM10 GABRP TFAP2A GALNT6 UGT8 DNAJC12 MPP6 PKP1 NDC80 TTC39A PHGDH SPDEF TFF3 IRS1 TTK PRR15L KIF14 GMPS STIL KRT16 CENPA PTTG1 TPX2 E2F3 AGR2 CA12 GALNT10 SRPK1 LDHB TTLL4 MELK BBS1 TRIM29 IGF2BP2 BUB1 TPBG MYO10 HHAT SLC2A10 P4HTM CPD RNF43 AMACR TOM1L1 MCCC2 YEATS2 SIDT1 SLC9A3R1 HEBP2 CHEK1 ACTL6A PFKP RAD51AP1 INPP4B SKP2 NRTN EFCAB11 KRT18	up	**
WEST_ADRENOCORTICAL_TUMOR_DN	0.0000001	0.0000035	0.7049757	-0.2803294	-1.642726	455	SEMA6A IL17RB TEK SLC47A1 RASIP1 CSDC2 CD55 SFRP4 WFDC1 CLEC3B CAT WNT4 PID1 ARHGEF15 INPP5K ST3GAL6 FLVCR2 VAMP2 CTDSP1 MSRA ALAS1 SLCO2A1 USP47 ABCB1 CASP9 IER2 CCNL1 APOD EIF4A1 LTBP4 SEMA3B RAPGEF4 KCNK3 CSRP1 TMEM204 BTG2 PRELP ABCG1 KLF6 NR4A1 JAM3 SIRPA TNS1 AOC4P APOC1 FOXC2 SORBS3 ATP10A RHOB CFD AHNAK CASKIN2 SRSF5 SORBS1 FMO2 KLF11 PARVB GMPR LAMC3 HOPX AXL CD302 DUSP1 CUL5 PTGIS MAFF PTH1R KCNA5 PKIG MYLIP ID4 CREM PHACTR2 LAMB2 CNNM2 GLUD1 CYP2A6 JUNB PTGER4 PODXL LYRM1 DDX5 THUMPD1 LUZP2 NPR1 RASSF2 CD34 FOS UBB KLF2 TNFSF13 RBKS FOSB IRF5 CBFA2T3 LRRC32 KCNN2 AOX1 MEIS3P1 FAXDC2 CD81 PPIG TOB1 KYNU PLEKHO2 SPOCK2 TCF7L1 TAGLN TSPO SOD3 GEM ICAM1 SF1 CALHM2 SCN7A LMOD1 CEBPD TPT1 MFAP5 EIF4EBP3 TOB2 ALDH6A1 PTCH1 EPHA2 RBMS3 PARVA TTC19 RORA RHOT1 MT2A CNN2 EHD3 MS4A2 EGR1 ACSM5 DKK3 NR4A2 EIF3L ZYX NUP88 ZFP36 FAM53B ADAMTSL3 MT1E SV2B ABHD14A PEBP1 PLN IRF1 RCBTB2 ADH1B SLC23A2 TPSAB1 CEP68 SIRT1 NR4A3 IRF4 LRP1 SYDE1 ZNF331 MEPCE SLC25A28 FBLN1 PLEKHO1 CCDC85B HDDC2 MT1X CDC42EP4 ALDH3A2 MYLK	down	***
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	0.0002008	0.0029643	0.5188481	0.3573199	1.641877	207	BUB1B NUP107 CCNB1 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CCNB2 DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL NUP155 KIF2C MAD1L1 CDCA5 LMNB1 MAD2L1 PSMD4 CENPO SPC24 INCENP ANAPC5 CDK1 CENPH BIRC5 PSMB5 KIF2A ANAPC7 NUP205 DYNLL2 PSMC4 CENPP KPNB1 RANGAP1 CDC23 PSMA5 TUBB2A PSME2 TUBA3D TUBA8 CENPQ ANAPC1 PSMD2 NUP85 CENPK CKAP5 PSMB3 CDC20 CENPM CHMP4C DYNC1LI2 CENPT RCC1 PSMB4 NUP62 BANF1 ANAPC2 TUBA4B ZWILCH SEC13 CHMP2A CENPE LEMD2 UBE2C TUBA1C PPP2R5D CLASP1 NUP93 CHMP6 DYNC1H1 DSN1 PPP2R5E FBXO5 PSMB10 PSME1 NSL1 TMPO	up	**
REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES	0.0025890	0.0244761	0.4317077	0.4114350	1.641464	74	CEP72 NEK2 CEP70 PLK1 DCTN2 HAUS5 CEP250 ODF2 SFI1 CDK1 CENPJ FGFR1OP MZT2A MZT2B CEP63 CEP192 TUBG1 NINL CKAP5 TUBG2 CDK5RAP2 HAUS6 HAUS4 CEP152 ALMS1 TUBGCP4 CEP164 NME7 CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT CDK11B TUBGCP2	up	*
CHICAS_RB1_TARGETS_LOW_SERUM	0.0034596	0.0305608	0.4317077	0.4097110	1.638083	76	HELLS DEPDC1 CDCA7 MCM4 TYMS DTL CDT1 CENPW MCM3 LMNB1 SOX4 EGFR UQCR11 CKLF SNRPE UQCC2 ZNF827 RNASEH2A RAD51D COX7C SYT1 PTN MCM6 MCM5 ROMO1 LSM7 ATOX1 COX5B WDR76 SYNE2 NNMT COX6B1 ZNF367 TOMM7 C4orf48 OST4	up	*
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP	0.0001366	0.0021371	0.5188481	-0.3120677	-1.637920	166	TEK CDH5 ST3GAL6 LDB2 NR3C1 FUCA1 TGFBR2 ZEB2 ERG ASAH1 OLFML2A CYB5A ACOT2 CAV2 TBC1D9 MTMR6 AHNAK SCP2 CPVL ITM2B DAB2 TMED5 PDE8A AXL MATN2 DSTN PPP2R5A ANXA3 CRIM1 EFR3A PRCP FRY ELF1 PDE6B MAGI2 MITF KCTD12 PODXL SDHD ACSL1 PLCG2 MSMO1 GNAI1 LRRC32 TOB1 TSPO ETS2 TNFAIP8 TFPI CEBPD CDKN1C ALDH6A1 SP100	down	**
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP	0.0000001	0.0000021	0.7195128	-0.2734227	-1.637688	507	SMAD6 RAB11FIP1 CXCL3 EREG ZNF366 PNPLA6 IL1A STAC OLR1 ADTRP CD55 SOWAHC IL1B LRRC8C DCSTAMP THBD LPL GFOD1 ST3GAL6 LONRF1 NEDD4L YPEL5 VAPA IL1RN SCARF1 IGSF6 ACER3 DNASE1L3 SNHG5 EDEM1 ARHGAP10 PTS ASAP1 B3GNT5 HBEGF RILP NAAA CLEC7A CSRP1 BTG2 COX18 GLS SLC7A11 ZNF697 PPP3CA RGCC MPHOSPH6 CD93 SPI1 TUBB6 CCNI CPED1 EFCAB14 TAPT1 TIMM10B CCL22 PTPRO MPEG1 ACSL3 PLAUR ST3GAL2 PRKD3 SLC7A8 VASP SOCS2 DPH3 CXCL2 HOPX UXS1 SMAD7 EVI2A INHBA SLC6A6 GPR157 IL7R PEF1 NUS1 TBC1D4 MAFF CRIM1 AKIRIN1 MOB3A MMP19 FAM102B FOXN3 PROCR CLN8 TRGC2 HCAR3 FMNL2 IL6 PHTF2 BCAR3 PHACTR2 AQP3 PPA2 ETV3 JUN MTMR14 SH3BP5 RAB31 RAC2 TREM1 PLK3 RCAN1 GLIPR1 LYRM1 SIGLEC15 ENTPD4 FSD1L REL CXCL5 TNFRSF9 SMIM20 LGALS2 TAGLN2 CST7 WDFY4 NDUFV2 SLC3A2 POGLUT1 RHOQ CALM1 TNFSF13	down	***
BILD_HRAS_ONCOGENIC_SIGNATURE	0.0000501	0.0008914	0.5573322	-0.3011938	-1.636269	216	CXCL3 EREG IL1A CD55 TBX3 IL1B LRRC8C PTPRE MBOAT2 LRRFIP1 BMP2 FOSL1 MYD88 DENND2C TRIB1 IER2 CCNL1 ATP2B1 CLCF1 B3GNT5 HBEGF PLXNA2 KLF6 MALL PTX3 TOR1AIP1 ADRB2 TCF7L2 MCL1 PDGFA ITPRIP CASP1 PLAUR MAP1LC3B CXCL2 HPSE DUSP1 ELK3 OXSR1 CALM2 TGFB2 PIAS1 PNMA2 DDX17 JUNB PPP1R15A ELOVL7 PNPLA8 CXCL5 TNFRSF10B PALMD FOS SPRY4 EHD1 SERPINB1 TSC22D1 DUSP5 PIM1 ADAMTS15 CCL20 GLTP	down	***
DODD_NASOPHARYNGEAL_CARCINOMA_UP	0.0000000	0.0000000	0.9653278	0.3182927	1.636145	1384	ATP10B CCNO SAA1 RHPN2 LTF ATP6V0A4 ALDH3B2 PRR15 RIBC2 KCNMB2 B3GALT5 SCIN ABCA13 MUC13 MYEOV ABCC2 PTPRT SLC16A9 FUT6 HHLA2 SPATA24 MYCBPAP FOXA3 ADH1C EYA1 GALNT14 OR7E14P FAM182B WFDC3 DNAH2 GMDS BDH1 GPT2 GABRP EPN3 SLC13A3 CECR7 CP CHST6 C5orf63 ANKFN1 SYNPR-AS1 PROM1 LRRC43 PPIP5K1 ADRA2A TRNP1 ARMC3 PTPRN2 MUC4 FUT3 WFDC2 FAM153A CIB2 C21orf58 TSHZ2 GCNT3 TOX3 MUC16 TTC25 GUCY2C MKS1 PLEKHA6 PLEKHH1 CCDC113 SPDEF TFF3 FANK1 PTPRH CCDC74A LCN2 MUC5AC AGFG2 ASIC1 SMPD3 PRR15L ALDH1L1 BCL2L15 SLC27A2 RHOV GALNT4 DAW1 SPAG17 FA2H COL28A1 FCER2 BCAS1 LYPD6B TTC26 SIX1 ACOT8 SAMD15 VSTM2L H19 C4orf19 KCNT1 AGR2 RAB36 GRHL3 DNAH3 CA12 CD163L1 PLS1 CIB1 MUC20 CCDC74B ASXL3 VILL C2orf81 DZANK1 LRRC27 PLEKHS1 EPS8L1 DNAI1 C6orf132 TJP3 MANSC1 RSPH1 ARMC4 SDR16C5 ANKUB1 STAG3 OSBPL2 SYTL2 C9orf116 SPAG16 SMAGP FOXJ1 TRIM29 TSGA10 FBXW9 MAP3K13 CCDC13 RPL32P3 BPIFB1 TMEM184A IQCD PSENEN REC8 SLC2A10 SYNE4 P4HTM GPR182 ODF2 KLHDC7A IFT43 C6 HYDIN AGBL4 WDR78 TPCN1 TTC22 SPEF2 TEKT2 IL20RB FAM216B EFCAB12 SRGAP3-AS2 CCDC89 CCDC114 DCDC2 BEST4 ANKMY1 C7orf57 WDR66 TGM1 AP1M2 C11orf16 NME5 RIPK4 SLC9A3R1 B3GNT3 CCDC148 NEK11 PDZK1IP1 ASS1 IFT172 STEAP4 GAS8 CBY1 CCL28 MSI1 DNAAF3 OXTR BACE2 SPATA17 CAPS DNAH11 FBXL8 SPAG8 CCDC136 KLHL3 FUT2 CCDC170 C4orf47 MGLL WWC1 CCDC40 OSBPL7 RECQL5 PTPN3 TXLNB GPX8 CCDC78 IKBKB FGGY PRRT3 TTC9 DRC1 FRMPD2 MB KIAA0556 DNER LRGUK LRRC6 DMKN FAM221A CROCC SPATA6L DNAH6 EFCAB6 ARHGAP39 CLMN KCNE3 SERTAD4 TNFRSF21 DIDO1 MDH1B SSUH2 TTLL9 WDR54 ANKRD54 SUN1 STX18 GIPR FAM81B IGHG1 REEP6 TMEM8B LRRC4 KIF19 WDR31 SPAG6 TCTN2 TRIM41 SDCBP2 KLHDC9 NEK5 CCDC88C EFCAB1 TTC6 TTC23L TRIM7 NF1 RAET1E RALGPS1 TNRC18 KIAA1211L LCA5 MYO5B AK7 TTC16 DNAH5 LRRC56 PRKAA2 CXCL17 FAM102A TMEM231 CASC1 TSPAN1 PPP1R36 FOCAD FAM86C1 C3orf67 ANKRD45 PIAS3 SNHG18 DENND6B KIAA1257 SPEF1 CAPS2 ST14 CYP2C8 NPHP1 COL1A1 NEK10 GDPD3 SPG7 SLC26A2 DNAH7 SPATA18 TSNAXIP1 EFCAB2 MNS1 C22orf15 LLGL2 ARHGAP32 CCDC151 TUBB2A FAM166B GPRC5C TPO IQCG RGS22 FBXO15 MORN2 C9orf152 PPOX CADM4 SLC13A4 CASP7 CNGA4 KIF21A PINLYP MSI2 MROH9 S100A9 CCDC146 TUBBP5 ATG9B HECTD1 PCDH9 GRIN3B USP43 SPAG1 TEKT3 IGHM LRWD1 SRD5A3 SPA17 PLAC4 SMIM22 SGSM3 FHL2 AHNAK2 EPB41L4B SLC9C2 IQCH TTLL10 THRB TRAF3IP1 TMEM232 DNAJB13 PROCA1 TMEM234 C15orf62 KCNB1 AGBL2 IQUB LINC00467 CCDC30 KLHL32 EFHC1 TCTN1 RSPH10B CATSPER2 CXCL1 PPP6R1 ENTPD3 ASRGL1 UPK1B ODF2L CDRT1 EML6 FAM174A LPCAT4 ODF3B VWA3B ANXA9 DNAI2 SPINK5 IGHA1 LRRC73 SMIM6 IFITM10 DYNC2H1 ZNF599 CHRNA3 FBXO36 MMP24 EDAR EFHB KATNB1 YIPF2 CH25H TMEM254 RSPH4A SLC41A3 VWA3A LRRC46 TMEM45B CCDC60 MVP STRBP GNAL CEACAM5 MICAL3 B9D1 CES4A LRP11 C19orf33 ULK4 DZIP3 TTC12 TMC5 ZNF445 RTEL1 TMEM72 SYBU CEP164 PCSK5 CCDC181 CLUAP1 DNAH1 OSBPL10 TUBA4B DLEC1 PRSS22 MAP3K9 R3HDM4 SLC25A29 CHMP1A MCU LRRC71 EYA4 ENKUR ERGIC1 RDH10 TCTEX1D1 TRAK1 WDR49 VPS9D1 GNA14 LRG1 WLS FAM83E ERBB2 TTC39C ENPP5 CASC2 ALDH3A1 RAB43 BCL6 LOXL4 GNE MAP1LC3A CMTM8 CGN CHL1 ZNF204P DHRS3 UBXN10 KIAA1522 BCAN NEIL1 GOLGA2 ALOX15 TMEM256 FBXO34 ADARB2 NSUN7 CYSTM1 DCDC1 CAPN9 KRT80 UBTF CLDN10 RIPK3 RORC FOLH1 ZMYND10 DHRS9 LXN TAX1BP1 ZER1 MUC1 PLIN3 STK11IP TK2 B3GNT4 TTLL5 GSDMC PLXNB1 APOBEC4 MOK HEMK1 MAP3K19 PPP1R16A KCNK6 TMCO6 NQO1 SPATA33 DNAL4 ZSWIM5 STK33 ACSBG1 PLAC8 KCNJ15 ARMC2 KLK10 MORN3 MED16 DNAAF1 WDR55 ZDHHC1 DYNC1H1 MAK SCRN2 TEKT1 ZDHHC13 ABLIM3 PPP1R13L REXO1 WDR63 SIGIRR CRAT RBM20 MST1 ST6GALNAC1 CNKSR1 NOXA1 PEX11A CAMK2G	up	***
REACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES	0.0056423	0.0444380	0.4070179	0.4391908	1.635837	53	COL17A1 MMP13 COL24A1 COL27A1 COL7A1 LAMC2 ITGB4 COL3A1 COL1A1 COL1A2 CTSV COL9A2 COL5A2 MMP7 COL11A1 COL5A3	up	*
ROSS_AML_WITH_AML1_ETO_FUSION	0.0051635	0.0418001	0.4070179	-0.3763543	-1.630139	61	IL17RB WFDC1 CAV1 TBXA2R IER2 CACNA2D2 LCP1 CD58 PTPN12 PTGIR RUNX1T1 KLF11 LAPTM5 VAMP5 HPGDS PALM RPS6KA1 CD34 ADPRM	down	*
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14	0.0011646	0.0127833	0.4550599	0.3770934	1.628205	124	CDK4 EIF2B5 TYMS NME1 RANBP1 CLPTM1L CISD1 YKT6 SMYD2 NSUN2 PKM SEC61A1 FBL DCTPP1 PES1 THOP1 CCT3 PSMB5 GNPNAT1 GOLGA5 UQCC2 EFTUD2 SLAIN1 UBFD1 DVL3 DTYMK MLEC TCEA1 SND1 PSMB3 PRMT1 TMEM147 SRSF1 PDIA4 TCERG1 RAB34 SMARCA4 HDLBP BANF1 SEC13 ERGIC1 TBCB RPN1 EIF4G1 APEX1 PTOV1 MRPL20 PIGQ PPP1R14B DDX41 PRRC1 MRPL12 GGA1 ASL NHP2 TMEM167A CS PPA1 FGF1 EBNA1BP2 IPO4 DNAJC2 PTP4A3 RCN1	up	*
ROSS_LEUKEMIA_WITH_MLL_FUSIONS	0.0029331	0.0267219	0.4317077	-0.3591099	-1.627844	69	SIDT2 ADCY9 CORO1C ZEB2 PBX3 ANXA5 DACH1 CES1 SCP2 DAB2 PTPRC CCND2 HEXB ARL6IP5 RAC2 RBKS NKG7 WHAMMP3 MEIS1 CLASP2 ADAM10 MBNL1 ARPC2 SCPEP1 JMJD1C KLRK1 FEZ1 BMI1	down	*
REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	0.0035449	0.0311149	0.4317077	0.3996575	1.626629	83	CEP72 NEK2 TUBB2B CEP70 PLK1 DCTN2 HAUS5 CEP250 ODF2 SFI1 CDK1 CENPJ FGFR1OP MZT2A MZT2B CEP63 CEP192 TUBG1 NINL TUBB2A TUBA3D TUBA8 CKAP5 TUBG2 CDK5RAP2 HAUS6 HAUS4 CEP152 ALMS1 TUBGCP4 CEP164 TUBA4B NME7 TUBA1C CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT TUBGCP2	up	*
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP	0.0000012	0.0000334	0.6435518	-0.2822931	-1.626354	375	SEMA3G CXCL3 HSPB7 TMEM100 CLIC3 EDNRB PPARG CLEC3B EMP2 GREM2 CYP4B1 BMP2 ENG LPL CD44 SAMHD1 SRSF7 TGFBR3 CD9 TRIB1 SYNC CCNL1 TXNIP KCNAB1 LTBP4 HBEGF OLFML2A EIF1 BTG2 EIF5 MAP3K8 PRELP KLF6 GLS SLC7A11 SPTBN1 SPRY2 CLK1 CES1 SRGN APOC1 RHOB PER3 SYNPO FOXO1 SORBS1 KLF4 AOC3 PEG3 RUNX1T1 FMO2 KLF9 KLF11 THBS1 BCHE PLBD1 NPR3 ABCC4 CCL3 PER2 CXCL2 ATF3 CD302 DUSP1 INHBA N4BP2L1 MATN2 RAP1GDS1 CYP26B1 TP53BP2 RASL12 ARHGDIB TGFB2 RPS6KA2 PDK4 MYLIP CTSS NEK7 OASL JUN MITF HSPA1B JUNB RABGAP1 PPP1R15A PODXL GLIPR1 PIK3R1 ACKR3 CD83 SELENBP1 PTGER2 MFAP4 REL GPRC5A CELF2 CD34 PELI1 FLNC EPHA3 FAXDC2 COL15A1 SOD2 RGS2 ADAM10 ABI3BP CLEC2B ETS2 JUND GEM GPX3 FGF2 PDLIM5 CPQ SLC31A1 TFPI IER5 CDC42EP3 CDKN1C ACACB MT1M RND1 METTL7A LIMCH1 NFKBIA	down	***
REACTOME_GPCR_LIGAND_BINDING	0.0000182	0.0003699	0.5756103	-0.2959122	-1.625542	257	FFAR4 CXCL3 HCRTR1 GPR17 RAMP3 CXCL16 EDNRB CD55 F2RL3 LHCGR WNT4 P2RY1 GPR65 RAMP2 HCAR2 CCL3L1 CCRL2 CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 ANXA1 SSTR1 WNT2B GNGT2 FZD4 NMUR1 ADRB1 GNG7 ADRB2 WNT3A GPBAR1 GPR4 PTGIR CCL22 TACR2 PTAFR CCL3 P2RY2 CXCL2 CCL4 PTGER3 XCL2 PTH1R GNRH1 WNT9A S1PR4 HCAR3 TAS1R1 DHH HRH1 ADRA1A PTGER4 CCR7 ACKR3 GPR183 PTGER2 SUCNR1 CXCL5 GPR37L1 WNT11 CCR4 FPR2 GNG5 GNB4 CCR1 GPR18 QRFP CCL20 CCR6 OPN3 HTR6 CXCR4 CCR9 PTCH1	down	***
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN	0.0011109	0.0124145	0.4550599	-0.3410377	-1.622029	97	MNDA PTPRE LPL LY86 EPB41L3 LILRB3 ADA BTG2 IFI30 ANXA5 GATA3 MCL1 KLF4 SELL JAM2 CD53 VAMP5 IL7R NINJ1 MN1 CSTA CCR7 GLIPR1 IRF8 CST7 KLF2 NKG7 GPX3 CEBPD MS4A4A FGFR1 RPL18A IL16	down	*
REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS	0.0057221	0.0449381	0.4070179	0.4007698	1.621358	79	BUB1B NEK2 CCNB1 PLK1 AURKB PTTG1 BTRC AURKA MAD2L1 PSMD4 SKP2 ANAPC5 CDK1 PSMB5 ANAPC7 PSMC4 CDC23 PSMA5 PSME2 FZR1 ANAPC1 PSMD2 PSMB3 CDC20 PSMB4 CCNA2 ANAPC2	up	*
REACTOME_MITOTIC_G2_G2_M_PHASES	0.0003903	0.0052941	0.4984931	0.3592768	1.620870	179	FOXM1 CEP72 NEK2 CCNB1 CENPF TUBB2B GTSE1 CEP70 PLK1 TPX2 E2F3 CCNB2 CDC25A MYBL2 DCTN2 HAUS5 CEP250 HMMR BTRC AURKA ODF2 SFI1 CDC25C PSMD4 PKMYT1 MNAT1 CDK1 CENPJ E2F1 PSMB5 PSMC4 FGFR1OP MZT2A MZT2B CEP63 CEP192 TUBG1 PSMA5 NINL TUBB2A PSME2 TUBA3D TUBA8 LIN37 PSMD2 PPME1 CKAP5 PSMB3 TUBG2 CDK5RAP2 HAUS6 HAUS4 PSMB4 CEP152 ALMS1 CCNA2 TUBGCP4 CEP164 TUBA4B FBXW11 NME7 TP53 CDC25B TUBA1C CLASP1 FBXL18 CEP290 DYNC1H1 PLK4 AKAP9 PCNT CDK11B PSMB10 LCMT1 TUBGCP2 PSME1	up	**
MATTIOLI_MGUS_VS_PCL	0.0035398	0.0311149	0.4317077	0.3893869	1.619713	96	IGHV4-61 RUVBL1 HBA1 TBRG4 IGKV4-1 MCM4 MCM2 IGKV2D-28 IGLV3-10 AKAP1 PSMD4 CAD PARP1 CKS1B NUSAP1 EXOSC2 AP3D1 CCT3 IGHG1 FADD PSMC4 LAPTM4B INTS7 SAP30 RRP9 MCM6 KIF21B LPCAT4 MCM5 SRSF1 NUP62 SMARCA4 TBCB IGLV3-19 SEPHS1 PAICS ENO1 NUP210	up	*
REACTOME_TRNA_PROCESSING	0.0042860	0.0362029	0.4070179	0.3868983	1.618731	98	NUP107 METTL1 XPOT QTRT1 PUS7 NUP155 GTPBP3 TPR NSUN2 TRMT61B TRIT1 TYW1 NUP205 RTCB TRMU PUS1 ADAT1 TSEN54 NUP85 ELAC2 CPSF4 AAAS POP7 NSUN6 RPPH1 RPP38 DUS2 NUP62 CTU1 WDR4 SEC13 OSGEP POP4 CDKAL1 NUP210 NUP93 RPP25 CTU2 ADAT3 TP53RK NUP214 NUP37 TSEN15 RPP40 NUP43 TRMT12 URM1 THADA CPSF1 MT-RNR1 TRMT1 NUP35 DDX1 NUP50 NUP133 MT-RNR2 POP1 TRMT44	up	*
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0	0.0049965	0.0406265	0.4070179	-0.3571945	-1.616849	70	SASH1 HSD17B11 BACH1 DDX6 ALAS1 PLA2G7 LIFR FOXP1 ADRB2 CYP4V2 MAP1LC3B ITIH5 NR1D2 TEF RECK CREBRF RHOQ PNPLA2 RIN2 VAMP4 AOX1 GABARAPL1 GEM SESN1 CEBPD	down	*
REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	0.0013491	0.0144633	0.4550599	0.3761743	1.616821	121	BUB1B NUP107 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 PFN2 MAD2L1 CENPO SPC24 INCENP CENPH BIRC5 KIF2A DYNLL2 DIAPH3 CENPP RANGAP1 RHOC DVL3 TUBB2A TUBA3D TUBA8 CENPQ NUP85 CENPK CKAP5 CDC20 CENPM DYNC1LI2 CENPT	up	*
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	0.0018265	0.0183346	0.4550599	-0.3402498	-1.616129	93	PECAM1 CDH5 ESAM CDC42 NCF2 RHOA RAPGEF4 RAP1A JAM3 ROCK2 ROCK1 VASP CLDN5 JAM2 PIK3R5 GNAI2 RAC2 PIK3R1 PLCG2 PRKCG MYL12A VAV3 GNAI1 ACTN2 ICAM1 CXCR4 ACTB RAPGEF3 CYBA ITGAL ITGB1 NCF1 PIK3CG	down	*
WINTER_HYPOXIA_UP	0.0040848	0.0346953	0.4070179	0.3950421	1.615238	87	CA9 AK4 SLC2A1 HILPDA ANLN GAPDH CA12 XPO5 NME1 RUVBL2 IGF2BP2 TPBG PTGFRN ALDOA MNAT1 TPD52L2 RHOC MRGBP GSS PLEKHG3 METTL22 PSMD2 TMEM30B P4HA1 TNS4 PFKFB4 MRPL14 NTMT1 BMS1 PGAM1	up	*
REACTOME_SIGNALING_BY_INTERLEUKINS	0.0000006	0.0000173	0.6594444	-0.2816721	-1.612293	365	IL17RB IL1A HMOX1 IL1B FYN CCL3L1 MYD88 VAMP2 S1PR1 MEF2A CDC42 IL1RL1 IL1RN PSMD5 CBL IL23A CD36 ANXA1 CLCF1 LIFR MAP3K8 LCP1 GATA3 IL18R1 TRAF6 HNRNPDL CRK ZEB1 MCL1 PTPN12 IL10 MAP2K3 STAT5A DUSP3 CCL22 FOXO1 CASP1 PTAFR STX3 SOCS2 SOCS5 CCL3 NFKB1 CDKN1A ITGAX NKIRAS1 CXCL2 IRAK2 VIM CCL4 IL7R CA1 IL24 HCK RPS6KA2 CD80 CNTF PPP2CA IL6 SOCS3 IL2RB JUN PSMA1 STAT4 JUNB JAK1 RAPGEF1 GSTO1 PIK3R1 GRB2 CREB1 OSM RPS6KA1 PRKACA TCP1 YWHAZ FOS UBB PELI1 PSMD12 FOXO3 MAPK8 PPP2CB TGFB1 HNRNPA2B1 TEC CD86 IRS2 PIM1 SOD2 CCR1 IFNLR1 CCL20 PITPNA ICAM1 FGF2 IL18 IL18RAP CEBPD HSP90AA1 TAB2 RIPK2 HSPA8 HAVCR2 BRWD1 PSME4 NFKBIA PAK2 DUSP7 RORA PSMD6 PSMD9 IL16 CNN2	down	***
ZHENG_BOUND_BY_FOXP3	0.0000003	0.0000107	0.6749629	-0.2756066	-1.611935	440	PEBP4 MS4A7 DENND5A LRRC8C LTA4H GPR65 RAPGEF2 FYN CD44 SAMHD1 CITED2 S1PR1 ELMO1 GIMAP6 ZBTB2 TGFBR2 TRIB1 ANXA1 ATP2B1 TRA2B LATS2 RAP1A MAP3K8 FOXP1 KLF6 PAG1 LCP1 GATA3 RB1 SPTBN1 HERC3 PPP3CC FLI1 KDSR GLDN DENND6A ITM2B LEPROTL1 STK17B SOCS2 PTPRC SELL SELP AXL ACTR3 PTGER3 CD53 ELK3 ARL4A PPP2R5C IL7R UBASH3B NUS1 TBC1D4 FAM76B CNOT6L VWF VCPKMT ZDHHC20 STK24 TBC1D5 ELF1 CREM PHTF2 NSMAF NEK7 RAB8B UTRN ETV3 PSMA1 LRCH1 STAT4 ZFP91 NSMCE2 ETS1 HK3 MAP4K4 ARHGEF10 IFNGR1 JAK1 PTGER4 CCR7 UBAC2 GPR183 PTGER2 MALT1 COBLL1 TPP2 GTDC1 RGS13 NDUFV2 CELF2 SNX9 GPRIN3 PELI1 AGPS KLF2 CDK17 HIVEP2 ECI2 ZNF175 ZFAND6 GIMAP1 NUP153 MRPL39 ENPP6 ZBTB1 TEC ZC3H12D UTP3 SBSPON MACF1 GPR18 PDE4B MBNL1 NR2E3 RBL2 LDLRAD4 SESN1 C3orf38 EXOC2 CHURC1 PARM1 MS4A4A PIP4K2A SIK3 ZBTB25 SP100 SSH2 JMJD1C DOCK10 B3GNT2 CYTH1 AIM2 SAMSN1 C21orf91 TLK1 GIMAP4 EVI5 IRF2 CDKN1B DUSP6 NR4A2 CX3CR1 PRKCH ICOS MAMDC2 KBTBD11 PIK3CG AQR CD69 PIAS2 SNX14 RCSD1 POLI MAN1A1 RCBTB2 MAP3K1 SLC23A2 TRAT1 NR5A2 ITGA6 NR4A3 CD226 JARID2 IRF4 AKAP13 TTC39B NFKBIZ ANKH C15orf48 ANKRD44 ADAM19 FAM107B HBS1L FEM1C CYTIP FLT3 TMEM71 SLAMF1 ITPR2 ANKRD28 AGO2 PGAP1 FASLG PTPN22 TMEM64	down	***
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN	0.0000601	0.0010468	0.5573322	0.3324463	1.611055	332	MNX1 PCSK6 TRIP13 CDC45 NEK2 CCNB1 CENPF DEPDC1 TTC39A BRCA1 CDCA7 CDCA2 RACGAP1 GTSE1 HILPDA KIF14 TRAIP POLE TOMM34 PLK1 CDCA8 CENPA PTTG1 CDC6 CCNB2 CDC25A MYBL2 PRC1 ORC1 MCM8 ZWINT CDT1 TNC TJP3 MELK EXO1 NUDT1 TNFRSF11A KIF23 PAFAH1B3 BUB1 TOP2A IDO1 AURKA PMS2P4 SAE1 KIF2C POC1A MPHOSPH9 RRM2 RGL1 RBM28 WDHD1 RAD54L KIF11 CHAF1B TRIM11 SLC9A3R1 KDELR2 ACSF2 IDH2 DYRK2 PSRC1 CASP6 CKS1B NCAPG2 CDKN2C CDK1 HDGF UCK2 BIRC5 TNK2 NAV2 E2F1 BPGM EZH2 RNASEH2A CCNE1 DLGAP5 TACC3 MNS1 COL5A2 DNM1 TK1 ENAH ATG9B GINS2 SLC1A3 CDC7 ERBB3 POP7 CXCL1 MCM6 KIF21B RAI14 MCM5 NFE2 CREB3L2 PSMB4 ATAD2 HTRA3 NUP62 ZNF286A PRSS8 PYCR1 MAP3K14 SMARCA4 VDAC1 BLVRB ABCF2 RAD51 SEC13 TCF25 ERBB2 SLC12A2 B4GALNT3 CENPE ADAM15 CGN CELSR3 SBNO2 CDC25B UBE2C CISH BCAT2	up	**
PID_CXCR4_PATHWAY	0.0022625	0.0219918	0.4317077	-0.3400003	-1.608175	94	FYN CDC42 FGR RHOA ITGA5 PAG1 CRK RHOB STAT5A FOXO1 UBQLN1 SSH1 PTPRC PIK3R5 GNAI2 HCK PIK3R1 ITGA11 RALB ITGA9 GNAI1 GNA13 ARRB2 CXCR4 VPS4B CD3G PTEN ITCH MAPKAP1 ITGB1 PIK3CG HLA-DRB1 CD3E ITGA6 PLCB2 CD4 PIK3R3 ITGA10 CD3D GNG2 BLK PIK3R6 JAK2 ITGA1 RGS1 PRKCZ STAT3 PIK3CA PTPN11 STAT1 LYN	down	*
REACTOME_SIGNALING_BY_NTRKS	0.0012857	0.0138102	0.4550599	-0.3200894	-1.605989	123	BDNF LYL1 FYN EGR2 FOSL1 ADCYAP1R1 MEF2A TRIB1 RHOA RAP1A CRK DUSP3 PTPRO REST ID3 RIT1 ID2 ARC SRF RPS6KA2 ID4 PPP2CA SGK1 JUNB RAPGEF1 PIK3R1 GRB2 CREB1 RPS6KA1 RALB FOS FOSB PPP2CB NAB1 IRS2 JUND VGF TIAM1 ADORA2A DUSP7 EGR1 DUSP6 ATF2 MAPK1 YWHAB KIDINS220 EP300 MEF2D	down	*
REACTOME_METABOLISM_OF_NUCLEOTIDES	0.0045865	0.0381929	0.4070179	0.3897502	1.605224	89	ENTPD2 AK4 GMPS TYMS UMPS XDH DPYS AK8 NME1 DNPH1 NUDT1 RRM2 NT5C1B ENTPD6 DCTPP1 CAD ENTPD5 UCK2 ATIC AK7 UCKL1 UPP2 DHODH TK1 DTYMK NUDT16 NT5M PFAS ENTPD8 ENTPD3 LHPP NME4 ENTPD7 GMPR2 PAICS TK2 DGUOK ADSL DPYD APRT TYMP AK9	up	*
REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	0.0004010	0.0054129	0.4984931	-0.3004747	-1.604680	183	FFAR4 CXCL3 HCRTR1 GPR17 CXCL16 EDNRB F2RL3 LHCGR P2RY1 GPR65 HCAR2 CCL3L1 CCRL2 ADRA1D TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 ANXA1 SSTR1 NMUR1 ADRB1 ADRB2 GPBAR1 GPR4 PTGIR CCL22 TACR2 PTAFR CCL3 P2RY2 CXCL2 CCL4 PTGER3 XCL2 GNRH1 S1PR4 HCAR3 HRH1 ADRA1A PTGER4 CCR7 ACKR3 GPR183 PTGER2 SUCNR1 CXCL5 GPR37L1 CCR4 FPR2 CCR1 GPR18 QRFP CCL20 CCR6 OPN3 HTR6 CXCR4 CCR9 ADORA2A EDN1 HEBP1 LPAR6 NPW C5AR2 CNR2 CX3CR1 C5 FPR1 BDKRB2 FPR3 UTS2B S1PR5 GPR55	down	**
BILD_MYC_ONCOGENIC_SIGNATURE	0.0008592	0.0100072	0.4772708	0.3549165	1.604526	181	SORD C12orf66 METTL1 CDK4 FGF11 FLAD1 KCNQ5 CDCA8 XPO5 EPS8L1 OSBP2 C19orf48 NLE1 LAMC2 SLC29A2 TTLL12 AIMP2 TGM1 MST1R SLITRK6 PHB ALG3 PES1 CCDC78 ATIC SLC12A8 NOP2 LINC00173 PA2G4 FAM86C1 COL1A1 DHODH NGFR PLEKHG3 MYBBP1A GEMIN5 AGPAT5 ANAPC1 CCDC137 DHRS1 LSG1 DGKA ERBB3 RRP9 GPATCH4 NOL6 ABCC3 ERVMER34-1 UTP20 FCHSD1 SSH3 RABEPK STMN3 EXOSC5 FARSA CYTH2 FARSB PFKM RNF213 CGN PAICS GOLGA2 FGFBP1 ADAM8 PDP1 SFXN4 KHNYN	up	*
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP	0.0000997	0.0016261	0.5384341	0.3372651	1.601589	281	DKK1 TRIP13 TP63 HKDC1 DDX11 SLC5A5 GALNT6 CCNB1 PSPH CHST4 PRIM2 SORD PPP1R14D IRS1 METTL1 ECT2 CCNB2 STC2 RBBP8 MCM4 MCM2 RAD54B XDH TRIM45 LSM5 WDR62 BZW2 KCNN4 MKI67 MRPL15 PCCB CYP24A1 HOMER3 PUS7 BPHL POLD2 MCM7 MAD1L1 PRKDC GCAT AMACR PEX6 DDR1 CAD ZNF507 PML PLA2R1 NCAPG2 IGFBP5 KRT18 MERTK ESRP1 LARP1 SSX2IP ARHGAP32 ROGDI RHBDD3 SLC22A5 SAP30 FXYD3 ENPP2 MARCKSL1 PFAS TSTA3 ERBB3 NPRL3 CXCL1 CKMT2 PRMT1 CLUH LRCH4 ZDHHC11 SF3A2 WDYHV1 PRMT5 AKAP6 LRRC14 FARSA NCDN SCRG1 FBN2 GRM6 SOX12 CELSR2 UBAP2L RAB25 PAICS EPHB4 ENO1 PPP2R5D HGF CORO1B LYPLA1 PCGF2 PDK2 BCL7A TBC1D10B ABHD2 TLE2 TCFL5 MPZL1 NCKIPSD SNTA1 FCGBP CEP112 ELL3 INHA ANK1 NUP214 EPS15L1 SLC12A9 GRHPR IPO4 RNF170 GPR27 HMBS GPR137 PTP4A3 CIC TSPAN15 NDUFA10 EIF4EBP1 ZC3H3	up	**
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN	0.0010106	0.0114801	0.4550599	-0.3063063	-1.600121	151	CD55 HHEX GFOD1 ZCCHC2 NEDD9 CD22 PDE2A LACTB B3GNT5 LCP1 HNRNPDL SLC25A37 UBE2D3 CD37 ID3 ZADH2 COTL1 PDE3B CNOT6L ARHGDIB AFF3 SNN MTPN BTG1 USP25 S1PR4 SH3BP5 ETS1 CCDC50 SNX2 CCR7 STX7 GMFG GYPC FRYL FAM43A WDFY4 CELF2 KLF2 SERPINB1 VPREB3 PDLIM1 ANKRD13A RNF2 TNFAIP8 UBE2D1 GPD1L CD19 STK4 BCAT1 CECR2 BANK1 ARHGEF18 FUS PLEKHA2 EBF1 PAX5 RCSD1 FCRLA SNRPN SMIM4 FAM111A BTBD1 CBFB ANKRD44 PUM2 RDH12 TNFRSF19	down	*
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP	0.0020092	0.0199155	0.4317077	-0.3248233	-1.600051	113	SLPI CD52 TSPAN4 MNDA SNX10 LPL SAMHD1 BCL2A1 LILRB3 BTG2 LITAF SIRPA GRN MSR1 MPEG1 CASP1 STX3 LAPTM5 MARVELD1 PTPRC CXCL2 CD53 HLA-DQA1 HCK PROCR CTSS C1QA TYROBP CD7 RRAS CD74 CHIA LGALS3 ORM2 CCR1 SELPLG GLTP GPX3 MS4A4A S100A4 CTSC NABP1 IQGAP1 LYZ CYBA C1QB S100A8 FPR1 MT1E QSOX1	down	*
BAELDE_DIABETIC_NEPHROPATHY_DN	0.0000011	0.0000310	0.6435518	-0.2736944	-1.599921	397	CD55 PHYHIP RDX BMP2 FYN LPL ST3GAL6 CITED2 ELF2 DYRK1A PRKAR1A NR3C1 TGFBR3 NEDD9 OTUD4 NFATC3 TMX4 APOD ANXA1 SEMA3B SERINC1 LITAF TMEM123 HNRNPDL MCL1 PDGFA HMGN1 SYNPO TLE4 BIRC2 HNRNPA3 PTPRO CASP1 YBX3 ACSL3 TMED5 GRK5 MYO1B RBMS1 CXCL2 VIM PAPSS1 AXL IGFBP2 ACTR3 EPS15 DUSP1 N4BP2L1 DSTN N4BP1 PAFAH1B1 CALM2 MAFF CRIM1 EFR3A PTH1R SACM1L CLIC5 KANK1 FRY BCAR3 NEK7 MAGI2 AQP3 PNMA2 RHOBTB2 DDX17 DNAJA1 VPS26A RCAN1 PTGER4 FERMT2 PODXL STX7 MORC3 ATP13A3 AP3B1 YWHAZ GPRC5A TOM1L2 PLCG2 CD164 NAPG ALDH3B1 MYL12A CR1 MME PPP2CB KIAA0232 NAB1 GALC ATXN1 TOB1 NPTN SPOCK2 PDE4B PHLPP2 HSPA2 PDLIM5 NBN CDC42EP3 CEBPD CDKN1C HSP90AA1 SP100 MEGF9 BCAM ULK2 OSER1 HNRNPC GLUL ACADM DNAJB9 CAMSAP2 TLK1 EIF4A2 EID1 FNBP1 ARHGEF18 ABI1 VPS13D UBR2 CDC14A SERPINE1 PEX14 GHR EXPH5	down	***
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	0.0010827	0.0121245	0.4550599	-0.3097509	-1.599729	141	FFAR4 HCRTR1 GPR17 EDNRB F2RL3 P2RY1 GPR65 TRPC3 ADRA1D TBXA2R ANXA1 HBEGF GNGT2 NMUR1 ABHD6 GNG7 GPR4 DGKE TACR2 PTAFR GRK5 P2RY2 XCL2 GNAQ GNRH1 RPS6KA2 RGS18 HRH1 ADRA1A PIK3R1 PRKCE GRB2 CREB1 RPS6KA1 RGS13 DGKG DAGLA FPR2 GNG5 GNB4 RGS2 QRFP	down	*
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP	0.0001095	0.0017625	0.5384341	-0.2944659	-1.599719	216	RAB11FIP1 KMO SLC12A6 GATA2 ZC3H12C ADCY9 EMP2 DPYSL2 ADCY4 RAMP2 RCOR1 FYN ECSCR AKAP7 ADRA1D YPEL5 FUCA1 TRIB1 ZEB2 SH2B3 ASAP1 CHMP1B FZD4 MALL SLC7A11 ABHD6 SIRPA SPTBN1 CES1 CD58 FLI1 KDSR ADARB1 ROCK2 TBC1D9 EPOR ZSWIM6 PAQR5 GRK5 NPR3 ID2 IGFBP2 LBH MEDAG ARHGDIB IL17D CABLES1 LRCH1 KCTD12 JAK1 PODXL FAM43A SIGLEC15	down	**
SASAKI_ADULT_T_CELL_LEUKEMIA	0.0017160	0.0174796	0.4550599	0.3614580	1.598731	152	FOXM1 TFAP2A BUB1B CCNB1 CENPF PTPRN2 KIF14 PLK1 PTTG1 ACOT8 TPX2 CCNB2 TYMS ZWINT MYL6B NME1 KCNN4 MKI67 TOP2A KIF2C MSX1 KIF11 MCM3 ETFA TFCP2 PARP1 TMED3 MRPS12 TRAPPC12 ARNT2 POLR2H VBP1 DLGAP5 GALK2 TK1 HDAC1 TP53TG1 SAP30 FHL2 CDK13 PLD1 RPA1 MED24 LPCAT4	up	*
DURCHDEWALD_SKIN_CARCINOGENESIS_DN	0.0000746	0.0012719	0.5384341	-0.2908703	-1.597299	231	RAB11FIP1 SLPI HMOX1 FCN1 FABP4 CAT CD44 CCDC88A SAMHD1 DDX6 QKI STX11 SEMA6D ASAP1 UBL3 GM2A RANBP9 ABCG1 HIPK3 KLF6 NFE2L2 TIPARP ADARB1 PTPN12 CSRNP1 LRRC57 KIAA0513 PIP5K1B TPP1 CADM1 SMAD7 CLIP4 PEAK1 N4BP1 UBASH3B SNN PIAS1 CD80 CCNY CDC40 BCAR3 PDE6B ESD UTRN AQP3 HPGDS CPEB4 MAP4K4 EEA1 DAPK2 COBLL1 SERPINB6 ATP13A3 YWHAZ RALB DEDD PXK SNX9 FOS AGPS TMX3 IRS2 C16orf72 APLP2 MACF1 ARAP2 CREBBP RAPGEF3 MAFK ZDHHC5 RNF38 KIF1B CAMSAP2 NRG1 PMAIP1 RAP1GAP UBAP1 CLIP1 TMEM43 HMGCS1 FHOD1 DCUN1D3 ITGB1	down	**
OISHI_CHOLANGIOMA_STEM_CELL_LIKE_UP	0.0001930	0.0028605	0.5188481	0.3327901	1.596977	304	PRLR ONECUT1 HKDC1 HABP2 DGCR9 NUDCD3 PHGDH GAL3ST1 MRPL46 NOL12 SPP1 SAYSD1 NNT PMS2 GON4L TOP3B ZSCAN2 DNPH1 XPNPEP3 BPHL AGT WDR3 NDUFS2 HOOK1 SETDB1 ZNF146 ANKEF1 ZNF226 MORC2 CDC42EP1 LRRC37A4P TBC1D8 ZNF507 MRPS30 ZNF587 PARP1 GEMIN4 EFCAB11 NRSN2 ZNF480 ZNF45 VN1R1 GMNN SCTR BPGM POLR1C SNRPE PRKAA2 ZNF623 VPS72 KLHL22 ZKSCAN5 IMPG2 ZNF692 RANGAP1 ZSCAN9 INTS7 SMG5 NFS1 EFCAB2 YIPF3 COG2 SPTBN5 SPTSSA PPOX ENAH MEGF8 SLC22A5 TRIM32 COX10 RMND5B PROX1 PGBD5 HNF1B IARS2 MAN2A1 ZNF202 MRPL24 ZNF432 SRPK2 ANXA9 HEATR1 ZNF749 SCYL3 TBC1D16 AATF PIP5K1A ZSCAN16 PATZ1 PMS2P1 ZNF224 ZNF212 SCNM1 LPGAT1 FBXW11 SRP9 PTPRF UBAP2L TP53 PRPF3 PCBD1 TIMM44 CLASP1 MZF1 ZNF562 POGZ CSTF1 RNF14 EIF2D METTL18 MRPS16 MLH3 TRIM52 SFT2D2 GPR75 DEPDC5 KIFAP3 MRPL2 GCC1 CRYZ PRCC MTR KLHL12 DGCR2 NDUFB2 MCCC1 FGF1 CTPS1 TMEM183A MIEF1 ZNF473 WDR12 ITPA SUCO SDHC KLHL20	up	**
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	0.0017007	0.0173883	0.4550599	-0.3353310	-1.594888	97	RAMP3 ADCY9 ADCY4 PLA2G10 RAMP2 CALCRL ADRA1D CYP4A11 RHOA ROCK2 PTGIR KCNMA1 ROCK1 KCNMB1 ACTG2 GNAQ MYH11 CALM2 MRVI1 ADCY2 ADRA1A PRKCE NPR1 PRKACA CYP4A22 CALM1 PRKCG	down	*
SMID_BREAST_CANCER_ERBB2_UP	0.0054110	0.0430747	0.4070179	0.3716602	1.591104	117	IGHV4-61 TSPAN8 ALDH3B2 ABCC2 BIK GALNT6 FUT3 PLEKHA6 EFNA3 CATSPERB FA2H ABCA12 IGKV4-1 GRB7 LRRC31 GSDMB SLC2A10 FGG CPD TRPV6 GCAT ASS1 C2orf72 NOL3 TSPAN1 SERHL2 QPRT SLC12A1 S100A9 PRMT7 KIAA0100 ABCC3 MED24 PRODH FFAR2	up	*
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	0.0038925	0.0333701	0.4317077	-0.3459640	-1.585977	76	PPARG FABP4 LPL EGR2 MED4 CD36 MED19 MED26 MED11 KLF4 CEBPA MED6 NFKB1 NCOA1 MED28 MED30 TGFB1 RXRA CEBPD CREBBP SREBF2 THRAP3 CCND3 MED17 MED31	down	*
REACTOME_LEISHMANIA_INFECTION	0.0001004	0.0016298	0.5384341	-0.2888202	-1.584239	227	RAMP3 IL1A GPR15 IL1B LHCGR ADCY9 ADCY4 RAMP2 FYN BAIAP2 CALCRL ADCYAP1R1 IGKV1-33 PRKAR1A ELMO1 CDC42 RXFP1 FGR TXNIP DPEP2 IGKV2-28 ADAM17 ENTPD1 GNGT2 ADRB1 GNG7 ADRB2 CRK GPBAR1 TXN IL10 PTGIR MEFV CASP1 NFKB1 ACTR3 WASF3 GNAI2 PTH1R ACTR2 HCK NCKAP1L IGLV2-11 MYO1C ADCY2 IL6 WASF2 JUN PTGER4 GRB2 CREB1 PTGER2 PRKACA IGKV3-20 PLCG2 CALM1 MAPK8 VAV3 GNAI1 GNG5 GPR84 GNB4 IGHV3-23 IGKV1D-39 IL18 ARPC2 HTR6 NLRP3 ACTB ADORA2A CD3G ARPC5	down	**
WEBER_METHYLATED_LCP_IN_SPERM_DN	0.0049404	0.0402895	0.4070179	0.9249788	1.583284	3	LEMD1 TSGA10	up	*
GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN	0.0029528	0.0267687	0.4317077	0.3593927	1.582854	143	MCM10 CDC6 TYMS CDC25A MYBL2 PLEKHA7 DTL ZWINT CASP2 C19orf48 MYO10 E2F2 RRM2 CDCA5 CHAF1B LMNB1 CHEK1 SLC25A10 SKP2 PPIL1 KCNE3 AAGAB GMNN ADAP1 DHX33 FEN1 COA4 CHCHD3 TELO2 CCNE1 SCLY MRPL11 ESCO2 GINS2 GEMIN5 CENPM RRP9 MRPL24 CKMT2 PPCDC GINS3 RCC1 NEFH STRBP ZNF93 DENR AMDHD2 ZWILCH WDR76 SNRPC MRPL48 CYB5B RFFL PPP2R5E TMPO TIMM10 NPM1 WDR5 RMI1 TIPIN	up	*
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION	0.0004395	0.0058187	0.4984931	-0.2955252	-1.581273	184	CXCL3 ACVRL1 IL17RB IL1A CXCL16 IL1B BMP2 CCL3L1 BMPR2 TGFBR2 IL23A TNFRSF8 CLCF1 LIFR IFNK IL18R1 PDGFA IL10 CCL22 EPOR TNFSF12 TNFSF15 MPL CCL3 CXCL2 CCL4 XCL2 INHBA IL7R IL24 TGFB2 CNTF FLT1 IL6 IL2RB IFNGR1 CCR7 OSM CXCL5 TNFRSF9 TNFRSF10B TNFSF13 CCR4 TGFB1 IFNAR1 CCR1 PLEKHO2 IFNLR1 CCL20 CCR6 IL18 IL18RAP CXCR4 CCR9 KIT TNFSF9 FLT4 TNFRSF10D CSF2 CD70 CSF2RB GHR TNFSF8 CX3CR1	down	**
REACTOME_GLUCOSE_METABOLISM	0.0057983	0.0454078	0.4070179	0.3960637	1.580139	74	NUP107 PGM2L1 GPI GAPDH ALDOC NUP155 TPR PKM PFKP GNPDA1 ALDOA SLC25A10 GCKR GOT2 ALDOB SLC25A13 BPGM NUP205 G6PC3 SLC37A4 NUP85 AAAS PFKFB4 NUP62 HK2 SEC13 PFKM PGAM1 ENO1 PPP2R5D NUP210 NUP93	up	*
ZWANG_DOWN_BY_2ND_EGF_PULSE	0.0005346	0.0068163	0.4772708	0.3416731	1.579676	217	FAM227A VWDE TROAP KIF18B DEPDC1 ZNF138 CDCA2 ZFP62 ANKZF1 E2F8 GTSE1 HILPDA DNMT3B CDCA8 ZNF714 STC2 TIGD1 ZNF117 ZNF283 CCNF ANKRD36B ZNF107 UQCC1 CCDC150 STAG3 DPY19L2P2 CENPL LINC00174 ARMC12 FAM27E3 FBXL8 CCDC136 ZNF587 DET1 PSRC1 CDKN2C ZNF440 KIF5A KCTD7 POC5 SMG9 RN7SL166P ZKSCAN5 FGFR1OP ZNF454 ZNF687 DCLRE1C HDHD3 TIGD6 ZNF37A TP53TG1 HSP90B2P SLX4 ZBTB7B STAG3L4 BRD8 PLD1 C12orf65 CATSPER2 ZNF780B TAS2R31 EPCAM GADD45G DPH5 ALOX12P2 CEP85 CYTH2 AP001372.2 ZSCAN22 SYNRG BCL6 ZNF526 ZNF354B ZNF33A SPATA33 ZNF630 ZNF740 MORN4 IFI44 ZNF678 MFSD9 PEX11A HSD17B7 ZNF805 TRIM59 DCLRE1A WDR89 LRRC37B ZNF30 ZNF429 STAG3L1 TOB2P1 ZNF302	up	**
NIKOLSKY_BREAST_CANCER_17Q11_Q21_AMPLICON	0.0053712	0.0429776	0.4070179	0.3766660	1.578683	99	PPP1R1B STAC2 CDC6 GRB7 ALDOC GSDMB TOP2A SEZ6 CPD ERAL1 ANKRD13B TADA2A DHRS13 CDK12 C17orf78 PHF12 RAPGEFL1 SRCIN1 SPAG5 PROCA1 PSMB3 HNF1B KIAA0100 TNS4 MED24 RAB34 MIEN1 MLLT6 ERBB2 SYNRG GOSR1 DDX52 TMEM98 FAM222B UNC119 LASP1 RPL23A PCGF2 MYO18A GJD3 PGAP3 TLCD1 PIGS CACNB1	up	*
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN	0.0013907	0.0148225	0.4550599	-0.3138774	-1.578048	126	SMAD6 SLPI TSPAN4 RBMS2 SNX10 EMP2 LPL SAMHD1 CITED2 INPP5A MSLN CD9 MAN2B1 ASAH1 IFI30 FOXP1 SPTBN1 ID3 MAP1LC3B GRK5 ATF3 RECK PER1 DUSP1 VAMP5 PEF1 SOCS3 SEC14L1 LAMB2 NOTCH1 ATP11A CD151 FOS KLF2	down	*
WELCSH_BRCA1_TARGETS_DN	0.0045011	0.0376525	0.4070179	0.3673407	1.577538	120	DDX11 CDK4 NPIPB3 MCM2 EIF3B SRPK1 CHAF1A PHKG2 AIMP2 SOX4 EMG1 CAD ALG3 SSBP1 AP3D1 ATIC TRAP1 MRPS12 DDT DNAJC7 CCNE1 PDCD11 LMNB2 SSRP1 MLEC CLTA POLD1 SLC1A3 RABEPK RCC1 SLC1A5 FARSA CKAP4 SMARCA4 HDLBP GTF3C2 VDAC1 BMS1 SNRNP70 UBAP2L MTHFD1 NMT1 APEX1 CDC25B SF3B2 POLRMT SRM HRAS SAFB EDC4 GCSH NDRG1 SEC24C XRCC5	up	*
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP	0.0007792	0.0091730	0.4772708	0.3394245	1.575657	224	LTF TSPAN8 CEACAM1 PRLR TP63 PLAT SCIN LAD1 PROM1 WFDC2 SLC2A1 LCN2 IGFBP6 SPP1 COL7A1 SOX9 STC2 ALDOC TNC MANSC1 FOXA1 TPBG SOX4 PFN2 MDK RBP1 CD24 RIPK4 HEBP2 PDZK1IP1 PROM2 SPINT1 PERP EHF DDR1 GRHL2 MBOAT1 WWC1 MARK1 TMED3 CXCL14 KRT18 ESRP1 GDPD1 MKRN1 FEN1 IRF6 PIAS3 ST14 KIF22 ENAH GALNT3 KRT19 EPB41L4B FXYD3 TMEM30B PLEKHB1 MARCKSL1 PTN ERBB3 ABCC3 KRT8 BTN1A1 NHSL1 CDCP1 CDH11 EPCAM SPON2 CDH1	up	**
PAL_PRMT5_TARGETS_UP	0.0014304	0.0151291	0.4550599	0.3500435	1.575146	178	TRIP13 HELLS PRIM2 TTK CDK4 RACGAP1 AURKB ECT2 NNT CCNB2 FIGNL1 UHRF1 MCM4 MCM2 TYMS NME1 NDUFB8 KIF23 MKI67 GCAT KIF11 CDC25C TOPBP1 AHCY INCENP CKS1B ANAPC5 POLE2 DTD1 GMNN PSMB5 CPNE1 TACC3 SNRPA TUBB2A SPTSSA GAS2 ANP32E PKP4 NDUFA13 NUP85 PTN CDC20 HAUS6 SRSF1 MARCKS U2AF2 INTS8 B9D1 PRIM1 ECH1 RFC5 ECHS1 WLS AURKAIP1 APEX1 SLC38A4 PTOV1 MRPL20 MRPL48 RCBTB1	up	*
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN	0.0011287	0.0125387	0.4550599	-0.2987629	-1.571502	164	GPD1 WEE1 EPAS1 FABP4 TIE1 LIPA CDH5 LPL AATK DDX6 QKI HSPG2 CD8A SH2B3 BMP1 MALAT1 KCNK3 GM2A PRELP STOM TNS1 MAPK8IP1 TFRC EPB41L2 KIF1C FABP5 PER3 SORBS1 PPP6R3 ZFAND5 BCHE HLA-DQA1 PDK4 MYO1C PDCD6IP ZFP91 ETS1 PRKCE TPP2 ACSL1 EHD2 EHD1 APLP2 SOD2 SOD3 TMEM109 MARC1 CYTH1 GRB10 ACAT1 NIPSNAP3A ETFDH ATP6V0A1 KLF15 ACVR1C ZBTB16 ZNF106	down	*
SABATES_COLORECTAL_ADENOMA_DN	0.0003115	0.0043542	0.4984931	-0.2904359	-1.570718	205	TMEM100 FABP4 CLEC3B SLC51B LYVE1 GREM2 RUNDC3B EPB41L3 SEMA6D BRINP3 CD36 LIFR WNT2B ABCG2 ANPEP PAG1 MS4A1 TNS1 SFRP1 CD37 CNN1 GLDN TBC1D9 AOC3 USP2 BCHE ITIH5 JAM2 WASF3 DUSP1 MYH11 CA1 PLAC9 AFF3 TRGC2 FAM107A ADCY2 SYNPO2 PDE6A CNNM2 CD48 KCTD12 BMP3 CNTN4 MFAP4 LGALS2 SIGLEC1 EPHA3 ENPP6 VPREB3 MEIS1 SCARA5 ABI3BP PHLPP2 GPX3 SCN7A LMOD1 RTN1 OSR1 SPIB MFAP5 TMOD2 MT1M DOCK10 MCOLN2 ABCA8 TMCC3 FAM13C	down	**
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP	0.0017927	0.0181937	0.4550599	-0.3320658	-1.569694	90	MNDA SNX10 LY86 SAMHD1 MARCO BCL2A1 IL1RN EOGT SLC11A1 LITAF IL18R1 MSR1 MPEG1 ITPK1 CXCL2 CD53 N4BP1 HLA-DQA1 HCK PROCR CTSS TYROBP ATP11A IRF8 CD74 ORM2 ICAM1 MS4A4A NFKBIA GIMAP4 LYZ CYBA C1QB PTGS1 MT1E	down	*
REACTOME_SIGNALING_BY_GPCR	0.0000005	0.0000153	0.6594444	-0.2607876	-1.568930	534	FFAR4 RBP4 CXCL3 HCRTR1 GPR17 RAMP3 CXCL16 GPR15 EDNRB GPIHBP1 CD55 F2RL3 LHCGR WNT4 ADCY9 P2RY1 GPR65 ADCY4 HSD17B6 RAMP2 GPC5 TRPC3 ARHGEF15 LPL PDE1B HCAR2 CCL3L1 RGS9 CCRL2 CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 PRKAR1A CDC42 RXFP1 PDE4C HSPG2 RHOA PDE2A ANXA1 RLBP1 SSTR1 HBEGF WNT2B GNGT2 FZD4 NMUR1 ABHD6 ADRB1 PPP3CA GNG7 ADRB2 AKT3 WNT3A ARHGEF2 GPBAR1 PDE4D CYP4V2 PPP3CC RHOB GPR4 ROCK2 ARRB1 PTGIR CCL22 DGKE TACR2 PTAFR ROCK1 GRK5 PDE8A CCL3 PDE3B P2RY2 CXCL2 ARHGEF26 CCL4 PTGER3 XCL2 GNAQ PIK3R5 GNAI2 PDE1C PTH1R GNRH1 RPS6KA2 WNT9A S1PR4 HCAR3 PPP2CA METAP1 ADCY2 PDE6A PDE6B RGS18 TAS1R1 DHH HRH1 ADRA1A ARHGEF10 PTGER4 CCR7 PIK3R1 ACKR3 PRKCE GRB2 GPR183 CREB1 PTGER2 RPS6KA1 PRKACA SUCNR1 CXCL5 RGS13 GPR37L1 CALM1 PRKCG DGKG DAGLA WNT11 CCR4 PPP2CB VAV3 FPR2 GNAI1 SLC24A1 GNG5 GPR84 PPP3R1 GNB4 CCR1 GNA13 OR52B6 RGS2 GPR18 GRK4 PDE4B QRFP CCL20 CCR6 OPN3 HTR6 ARRB2 TIAM1 CXCR4 LRP12	down	***
SANSOM_APC_MYC_TARGETS	0.0010433	0.0118276	0.4550599	0.3395084	1.567684	214	FOXM1 TICRR PHGDH METTL1 POLE CENPA LIG3 SHMT2 ZFP64 INTS1 NUB1 NME1 WDR62 SMARCC1 CARD11 QTRT1 POLA2 GTPBP3 MCM7 WIPI2 MCM3 SEC61A1 MCCC2 SOX4 GAS8 PSRC1 THOP1 KNSTRN ING4 CTDSP2 ATIC SSX2IP TRIM7 SAPCD2 ANKRD39 DENND6B TELO2 POFUT1 LMNB2 TUBB2A HIRA DPH2 MYBBP1A GEMIN5 DNMBP SLC1A3 COX10 ABCC10 GTF3C1 HNF1B RRP9 BCL2L1 KPTN NSD1 PIP5K1A LHPP OGFR NTMT1 CDC42BPA TMEM141 WDR4 NUBP2 RASSF4 ZMYND19 BCAS3 EIF4G1 SMPD4 MTHFD1 TP53 SIGMAR1 NELFA DNM1L PIAS4 SART3 ASCL2 TRAPPC6A NPTX2 ROR2 ALKBH2 USP20 MED22 SFXN2 SCRN2 PRPF19 SCAMP4 ATRIP NHP2 NDRG1 CXXC1 SHMT1 TXN2 TP53RK MEN1 LFNG DDX49 SEMA4D ZBTB48 ABCB8 PRRC2C	up	*
LU_EZH2_TARGETS_UP	0.0006328	0.0076788	0.4772708	0.3343509	1.565223	237	FGA BIK PPP1R1B RUVBL1 S100A2 PAGR1 THOC3 DDIT4 NUDCD3 PRIM2 PHGDH ZP3 AP1S1 TRIB3 MYL6B TRIM16L NUDT1 PODXL2 ODF2 IFT43 SNCG SNHG11 ZNHIT1 PSMD4 CBY1 KLHL35 PIH1D1 PRMT6 WASH2P ISOC2 BCAS4 WDR54 ADAP1 TCF20 KLHDC9 TRAPPC12 ARTN ETFB UNC45A TSPAN17 JOSD2 ZNF133 LONP1 ZMAT5 RAD51D CASP7 HDAC1 MGMT DLK2 AHNAK2 S100A13 ZNF814 RMND5B KLHDC3 FAM71E1 CENPV ZNF616 RPUSD1 WDR83 SURF2 LSM7 OGFR CBR1 HAGHL ELFN2 MIEN1 TMEM141 AMDHD2 ATOX1 ARL17B TRIP6 TYSND1 NDUFA8 MPG PPP1R14B ALKBH2 ZNF629 MFSD3 PDXP SIGIRR COMTD1 RPL36 LPCAT1 PSMB10 MEX3D RPLP0P6 PGAP3 PAQR7 PMVK TLCD1 RPS6KB2	up	**
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP	0.0000836	0.0013979	0.5384341	-0.2827955	-1.562742	260	WEE1 SECISBP2L CD55 ATXN3 SAMHD1 BACH1 DYRK1A OTUD4 RCHY1 PDCL ZEB2 ANXA1 KLF6 EIF4E FOXJ3 CRK CLK1 BTG3 PDE4D MCL1 TIPARP KPNA5 TBC1D9 DUSP3 STK17B STX3 ZNF24 NR1D2 CXCL2 ATF3 CAPZA2 DUSP1 GNAQ N4BP1 SMNDC1 RSRC2 TDRD7 ZNF330 MOB4 ID4 RYBP CREM COPS2 DCTN6 PNO1 NEK7 OASL NECAP1 JUN CELF1 SHOC2 DUSP8 RCAN1 PPP1R15A WTAP IFRD1 THUMPD1 SNRK AGFG1 SLC3A2 CDK17 LSM6 CCP110 BAZ2B GNAI1 GABARAPL1 GNA13 ARPP19 GEM FGF2 RLF RAB5A UBE2D1 SP100 POLR2M NUP98 OSER1 NFKBIA DNAJB9 ITCH TLK1 PMAIP1 YTHDC1 KAT5	down	**
MCCLUNG_CREB1_TARGETS_UP	0.0048820	0.0399308	0.4070179	-0.3437582	-1.562329	74	OSBPL1A BDNF CDH13 IDI1 LMNA BZW1 KLF10 ASH2L ADARB1 AQP4 ID2 CPLX1 HSPA1B ACKR3 HSD17B12 CAP1 CDK14 FOS	down	*
WILCOX_RESPONSE_TO_PROGESTERONE_UP	0.0043016	0.0362029	0.4070179	0.3589014	1.559420	130	MUC5B PCSK6 KIF20A MDM1 HJURP FANCI ELOVL6 CCNB1 CENPF PBK TTF2 NDC80 ASPM CDC6 CCNB2 SMPDL3A TYMS PRC1 HBB KIAA0895 HMMR MAP7 CEP55 TOP2A RRM2 WDHD1 FADS2 CDKN2C NUSAP1 CDK1 NCAPG PEG10 DLGAP5 GALK2 HMGN3 TK1 CENPQ IFNAR2	up	*
ENK_UV_RESPONSE_EPIDERMIS_UP	0.0004288	0.0057182	0.4984931	0.3315271	1.558767	253	PKP2 RUVBL1 GALNT6 PRSS2 FUT3 SLC2A1 HILPDA NPIPB3 POLE KRT16 ESPL1 CYP27B1 LSR TYMS SHMT2 XPOT TNC RUVBL2 PAFAH1B3 HOMER3 ITGB4 MDFI AIMP2 TGM1 ACTL6A PFKP XRCC1 EHF FDXR PHB FUT2 CMAS OSMR ULBP2 ATIC TNFRSF25 ACP6 SLC25A13 CDH3 CPNE1 KXD1 METTL3 DNAJC7 TPD52L2 NET1 DPP3 TUBG1 SPG7 PSMA5 COPS7B HDAC1 POLD1 ELAC2 CCT7 CDC20 LIPG BCL2L1 ENTPD3 STAMBP SURF2 CACNB3 RCC1 SLC1A5 STK39 PRMT5 ZNF212 ME1 SCO2 PRIM1 ANAPC2 HK2 PRSS22 SNX7 CARHSP1 STK25 PGAM1 XPC NMT1 HGS ADAM8 COPZ2 KRT17 DHRS9 DDB2 PLXNB1 PRKAG1 APEH USP20 SRM ADSL RWDD2B CES2 TMPRSS4 TUBGCP2 VLDLR	up	**
REACTOME_TOLL_LIKE_RECEPTOR_9_TLR9_CASCADE	0.0056223	0.0443564	0.4070179	-0.3385168	-1.557025	80	MYD88 MEF2A MAP3K8 TRAF6 MAP2K3 DUSP3 LY96 NFKB1 NKIRAS1 IRAK2 TLR4 RPS6KA2 PPP2CA JUN EEA1 CREB1 RPS6KA1 FOS UBB PELI1 MAPK8 PPP2CB PIK3C3 TAB2 RIPK2 NFKBIA DUSP7 UBE2V1 DUSP6 ATF2 MAPK1 UBE2N HMGB1 MAP3K1 MAPK7 SKP1	down	*
IVANOVSKA_MIR106B_TARGETS	0.0055497	0.0439600	0.4070179	-0.3398953	-1.555812	79	SIK1 SFR1 HPS5 NCEH1 KLF10 BTG3 FBXL5 EFCAB14 CYBRD1 TBC1D9 KIAA0513 CDKN1A NKIRAS1 UXS1 CLIP4 TMEM9B JAK1 TNFRSF10B DEDD PKD2 PKIA ZFYVE9 CDC37L1 PLSCR4 DAZAP2 RNH1 PURB TRIM36 CFL2 AKTIP MAPK1 CLOCK	down	*
SENESE_HDAC1_AND_HDAC2_TARGETS_UP	0.0002754	0.0039193	0.4984931	-0.2897145	-1.552973	201	CXCL3 EREG IL1A CD55 ROBO4 TIE1 LPXN BMP2 LDB2 FOSL1 BCL2A1 TGFBR2 DNAJB14 SH2B3 SPIRE1 PTX3 CAMTA1 JAM3 SFRP1 CES1 SRGN PDE4D TFRC MCL1 MYCT1 SLC7A2 KDSR PTPN12 PLAUR LAPTM5 IRAK2 CCND2 PLEKHB2 ELK3 IL7R UBASH3B NUS1 MAFF IL24 AFF3 TMOD1 CREM PHTF2 SNAP23 CPEB4 RAC2 PCGF5 PSTPIP2 CXCL5 TNFRSF10B GFPT2 GPR3 PPTC7 KYNU GNA13 RGS2 SNHG16 CCL20 GEM CEP170	down	**
KEGG_WNT_SIGNALING_PATHWAY	0.0017661	0.0179571	0.4550599	-0.3042245	-1.552630	135	SFRP4 WNT4 SOX17 FOSL1 FRAT1 NFATC3 RHOA WNT2B NLK FZD4 PPP3CA SFRP1 WNT3A TCF7L2 PPP3CC ROCK2 DAAM2 ROCK1 CXXC4 CCND2 PPP2R5C PPP2R5A PRICKLE2 SIAH1 WNT9A PPP2CA PSEN1 NKD2 JUN RAC2 PRKACA CACYBP PRKCG MAPK8 WNT11 PPP2CB PPP3R1 CSNK2A2 TCF7L1 SMAD2	down	*
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP	0.0058299	0.0455262	0.4070179	0.3602149	1.548442	119	CEACAM1 PCSK6 FOXM1 SLC26A4 BUB1B CCNB1 CENPF NDC80 TFF3 TTK GINS1 PLK1 AURKB PTTG1 CCNB2 MYBL2 CETP SMAGP BUB1 TOP2A KIF2C KIF11 LMNB1 RBP1 SPRY1 DCLK1 CKS1B CDK1 PEG10 SPAG5 RAPGEF5 TBX1	up	*
WIERENGA_STAT5A_TARGETS_DN	0.0016135	0.0167489	0.4550599	-0.2951305	-1.547954	157	SMAD6 FCN1 GCSAML PECAM1 GAPT WFDC1 FCER1A GFOD1 STX11 CD9 DENND2C JAM3 CD93 ROCK2 PTGIR SPNS3 CLDN5 MPL COTL1 SELP ARAP3 FCER1G SBDSP1 WASF3 PLEK UBASH3B VWF RGS18 CAPN11 NOTCH1 ETS1 MSRB3 IRF8 PSTPIP2 OGFRL1 PPM1F PLCG2 GJA4 DOK3 PDLIM1 IRS2 CTIF MEIS1 PLEKHO2 LDLRAD4 VASH1 CGRRF1 CXCR4 SCPEP1 ADORA2A BANK1 LYZ TREML1 C5 LHFPL2 ZYX PLXDC2 EFNB2 GNG11	down	*
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP	0.0000055	0.0001267	0.6105269	-0.2661347	-1.547606	382	RTKN2 CXCL3 SEMA6A EREG HSPB7 AKAP5 ARHGAP31 IL1A MS4A7 DENND5A USP12 CD55 KCNA2 ZC3H12C IL1B P2RY1 EMP2 RDX RAPGEF2 MIR22HG CD44 EMCN STXBP6 CCRL2 DDX6 NEDD4L FOSL1 UBE2FP1 CYP4A11 IL23A ZEB2 KCNAB1 TMPRSS6 ATP2B1 CLCF1 SGMS2 ADAM17 PRMT5-AS1 MTF1 BTG2 RNF144B FZD4 LITAF HIPK3 PTX3 EIF4E MOB3C LDHAL6A AGBL1 MAP2K3 STAT5A TBC1D9 SNAI1 PTPN21 LIMS1 PLAUR PXDC1 DRAM1 C1QTNF7 NFKB1 C4orf33 CXCL2 IRAK2 HOPX CCL4 PNRC1 TBX5 MAFF KREMEN1 VWF RASGEF1B AFF3 TGFB2 SNN NINJ1 ZCWPW1 AXDND1 KANK1 CD80 IL6 C9orf131 PIKFYVE SERPINB8 JUN PNMA2 CNTN4 HSPA1B PLK3 EPC1 RHOJ PPP1R15A WTAP ELOVL7 FERMT2 CD83 IRF8 FSD1L REL TNFRSF9	down	***
REACTOME_OPIOID_SIGNALLING	0.0056895	0.0447460	0.4070179	-0.3403361	-1.546777	74	ADCY9 ADCY4 PDE1B PRKAR1A PDE4C GNGT2 PPP3CA GNG7 PDE4D PPP3CC GNAI2 PDE1C PPP2CA ADCY2 CREB1 PRKACA CALM1 PRKCG PPP2CB GNAI1 GNG5 PPP3R1 GNB4 PDE4B	down	*
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN	0.0009793	0.0112168	0.4550599	0.3299850	1.546751	242	IGHV4-61 DKK1 CEACAM1 PTPRZ1 CA9 BBOX1 EPHB3 GALNT14 KRT5 KCNK5 GABRP S100A2 CP UCHL1 IGF2BP3 MPP6 PSPH PKP1 MUC16 PHGDH TUBB2B KRT16 IGKV4-1 AKR1C1 TBX19 SOX9 FERMT1 COCH GLDC PDE9A IGKV2D-28 LDHB TTLL4 CLDN1 IGLV3-10 KCNN4 TRIM29 IGF2BP2 PRKDC TMEM45A GPSM2 RBP1 EGFR PDZK1IP1 SOX11 PERP WNT5B PLOD2 TNFRSF21 IGHG1 TRIM2 GJB3 PSAT1 PEG10 PDK1 SRD5A1 LGR5 CRLF1 CHST3 FNDC4 TUBB2A SSRP1 S100A9 ANP32E MMP7	up	*
YANG_BCL3_TARGETS_UP	0.0004112	0.0055365	0.4984931	0.3253019	1.546657	279	MMP13 TF PLAT FOXM1 KIF20A PARPBP ELOVL6 CP CCNB1 UBE2T PBK CDCA2 RACGAP1 TRAIP IGFBP6 NDUFS6 AURKB PTTG1 ECT2 ESPL1 CCNB2 LSR PRC1 LRRC27 CXCL10 MKI67 KNTC1 BUB1 TOP2A AURKA KIF2C COASY RRM2 LIPE PEX6 B3GNTL1 HPR RAD51AP1 KHK BACE2 CKLF NRTN TNIK KNSTRN CDKN2C NUSAP1 IGFBP5 CDK1 TNFRSF21 MERTK E2F1 CTXN1 STAT2 DGAT2 SDCBP2 SAPCD2 RTP4 RAPGEF5 CPT1B IRF6 MOV10 DLGAP5 TACC3 KIF22 SLC37A4 KIF20B SPA17 SMIM22 CEP128 PTN ABCC9 CDC20 NAT8L CKMT2 CENPT CKAP2 RAB15 PARP14 PFKFB4 CH25H MYH3 CCNA2 DTX3L TXNL4B SYBU PCSK5 PFKM ARHGAP11A SCOC GBP2 GNA14 VWA1 ABO GPX7 UBE2C RASGRP1	up	**
LENAOUR_DENDRITIC_CELL_MATURATION_UP	0.0017000	0.0173883	0.4550599	-0.3196587	-1.546213	107	STAC PPARG FABP4 CAT LIPA LPL CITED2 CD1C GAS6 DNASE1L3 CYB5A ACOT2 ABCG1 RNASE1 TFRC APOC1 FABP5 CCL22 PTPRO CEBPA CCND2 DUSP1 INHBA HLA-DQA1 CCR7 CD83 SERPINB6 PKD2 CD74 CR1 DUSP5 CD86	down	*
LIU_VMYB_TARGETS_UP	0.0017000	0.0173883	0.4550599	-0.3196087	-1.545972	107	SLC31A2 IL17RB DPYSL2 TRPV2 FYN THAP9-AS1 MED4 PCOLCE2 ABCG2 CSGALNACT2 LHX6 TUBB6 FABP5 KLF11 CLIC4 RUFY3 CRIM1 VCPKMT NCOA1 USP25 EMP3 RPS6KA2 IDS RHOQ ZBTB1 CTNNAL1 BNIP3L HSPA2 MGAT2 CXCR4 ULK2 ICAM3 MMD GRB10 DNAJB5 ETFDH PSIP1	down	*
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP	0.0033931	0.0301661	0.4317077	-0.3080610	-1.545639	123	RCOR1 CD44 NEDD4L NEDD9 HBEGF KLF6 GATA3 TRAF6 CD93 SPRY2 SLC19A1 SRGN CSRNP1 KLF4 FAM49B CXCL2 ATF3 SERTAD2 ZNF330 RBPJ ARL6IP5 GZF1 SGK1 ETS1 RCAN1 PTGER4 SELENBP1 HOMER1 GPRC5A FOS SPRY4 JMJD6 TGIF1 CNOT7 ME2 CDC42EP3 ACAP2 PTCH1 SOAT1 RND1 NFKBIA JMJD1C EDN1 RORA PIM3 EGR1 CHIC2 ZFP36 DNAJB4	down	*
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP	0.0000258	0.0005037	0.5756103	-0.2711714	-1.540345	328	NLRC4 CD300LF ZNF366 SIDT2 MS4A7 CD101 ST8SIA6 SCIMP LTA4H C18orf32 FIG4 PDE1B LY86 KIAA1109 FLVCR2 ELMO1 MANBA NCF2 AGTPBP1 TET2 LAMP1 ATF7IP2 ACER3 SIGLEC6 CD36 SIRPB2 MALAT1 ASAH1 RASGRP4 GM2A IFI30 ANXA5 CYB561A3 SLC7A11 ZFYVE16 CD37 ZYG11B CCNI EVI2B SGTB MEFV CASP1 ST3GAL2 GAA SYCP2L MYO15B MGAT4A PTPRC PAPSS1 ALOX5AP EVI2A HEXB CLN8 PRCP CTSS CD48 GIMAP2 CPEB4 USO1 DNASE2 FOXN2 CSTA PSTPIP2 IDS HERC2P3 ZNF555 TRAK2 DYM NKG7 CD74 TIMP2 ZFAS1 ATP6V1A RPL21 ATXN1 NBEAL1 CSNK2A2 MR1 IL18 SLC35D2 PUS10 SLC25A20 CXCR4 ORMDL1 ALDH2 SLC2A9 AMZ2P1	down	***
REACTOME_INNATE_IMMUNE_SYSTEM	0.0000000	0.0000005	0.7477397	-0.2440756	-1.539766	857	POLR3H SIRPB1 NLRC4 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 FCN3 IL1B MNDA LTA4H CAT RAB44 CLEC12A LRRFIP1 PTPRB OSCAR FYN CD44 LY86 FCER1A BAIAP2 MYD88 CHIT1 CYB5R3 CD300E IGKV1-33 PAFAH1B2 C5AR1 CLEC10A YPEL5 MEF2A ELMO1 CDC42 MANBA NCF2 VAPA FUCA1 PSMD5 LAMP1 SLC11A1 NFATC3 LILRB3 FGR CASP9 RHOA TXNIP CD36 SLC44A2 DNAJC3 MAN2B1 IGKV2-28 CD33 ARSB ASAH1 RAP1A RASGRP4 GM2A CLEC7A MASP1 MAP3K8 RNF125 ANPEP PTX3 STOM LAIR1 PPP3CA SIRPA TRAF6 CD93 GRN LAMTOR3 CRK UBE2D3 TXN ATP6V1H RAB14 ATP6V1B2 CD58 CST3 MAP2K3 FABP5 CFD DUSP3 CCL22 BIRC2 SDCBP MEFV CASP1 BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D LY96 CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX NKIRAS1 PTPRC IRAK2 SELL HPSE ATP6V0D2 TLR4 ARHGAP9 ACTR3 SFTPD CD53 CAPZA2 FCER1G WASF3 GCA KLRD1 C4BPB DEGS1 CD300LB CMTM6 ACTR2 GLB1 HEXB HCK HGSNAT RAB6A NCKAP1L RPS6KA2 PRCP IGLV2-11 MYO1C PPP2CA WASF2 MUC3A CTSS PSEN1 SNAP23 C1QA JUN PSMA1 VAT1 RAB31 HK3 CTSZ RAC2 ATP6V0B TYROBP TREM1 HSPA1B ATP11A RHOG ENPP4 EEA1 GLIPR1 PIK3R1 GMFG PRKCE GRB2 CREB1 MALT1 SIGLEC15 SERPINB6 RPS6KA1 CAP1 PRKACA IGKV3-20 PLCG2 FOS ATP6V0D1 UBB PELI1 CALM1 PSMD12 ICAM2 ALDH3B1 MAPK8 TREX1 KLRC2 BIN2 CR1 MME PPP2CB TIMP2 SIGLEC14 VAV3 DOK3 SERPINB1 TEC FPR2 ATP6V1A TSPAN14 PIK3C3 DYNC1LI1 ATP6V0C GPR84 PPP3R1 CD81 LGALS3 IGHV3-23 ORM2 BRI3 PLEKHO2 ADAM10 IST1 IGKV1D-39 COMMD9 UNC13D CCR6 LAT ARPC2 HSP90AA1 TAB2 RIPK2 NLRP3 HSPA8 UBE2D1 ACTB PSME4 CREBBP METTL7A ICAM3 CD19 TLR10 NHLRC3 NFKBIA SIGLEC9 CTSC CD3G ARPC5 PAK2 KLRK1 DUSP7 SNAP29 AIM2 P2RX1 ITCH PSMD6 IQGAP1 CREG1 PSMD9 CNN2 ANO6 LYZ MS4A2 ABI1 UBE2V1 CYBA ATP6V0A1 SUGT1 IGKV2-30 C5AR2 C1QB CTSH DUSP6 TMEM30A ATP11B ATF2 CLEC4E C5 MAPK1 ITGAL TREM2 FTL NCF1 S100A8 RAB37	down	***
LIU_PROSTATE_CANCER_DN	0.0000025	0.0000620	0.6272567	-0.2646089	-1.533596	415	RBP4 EPAS1 TMEM100 SOSTDC1 FOXF1 SLC47A1 FGD5 WFDC1 ADCY9 ADCY4 CYP4B1 FYN TXNL1 CAV1 CORO1C TGFBR3 GAS6 EOGT EPB41L3 HSPG2 SEMA6D STARD4 TACC1 WNT2B RAP1A CSRP1 MASP1 ECHDC1 HSPB1 PRELP CAV2 DES STOM GATA3 TNS1 KANK2 BTG3 TUBB6 PPP3CC CFD PER3 KCNMA1 SORBS1 BNIP2 CASP1 AOC3 KLF11 GRK5 CLIC4 MYO15B ITIH5 MARVELD1 RBMS1 CCND2 DSE WFS1 ACTG2 CLIP4 SLC6A6 VAMP5 PRICKLE2 MYH11 CRIM1 MRVI1 RASL12 CNRIP1 TGFB2 PDK4 TSPAN18 ID4 CPAMD8 SYNPO2 PODN AQP3 LAMB2 NDNF C20orf194 SLC14A1 MSRB3 CCDC50 DUOX1 RHOJ FERMT2 PIK3R1 ACKR3 GYPC PTGER2 PREX2 MCAM EHD2 PKD2 FLNC MME FXYD6 TIMP2 VAV3 ITGA9 TGFB1I1 PDLIM1 MEIS1 MYOCD MRGPRF SBSPON RIMKLB LTBP1 MR1 TAGLN ETS2 LMOD1 CDC42EP3 ALDH2 TBC1D1 ACACB GPD1L EPHA2 SCPEP1 S100A4 METTL7A TTC28 KIT TIMP3 PDE4A MAGI2-AS3 LYST FGFR1 COL13A1 NR3C2	down	***
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN	0.0004723	0.0061794	0.4984931	0.3233658	1.531413	275	TRIP13 FOXM1 TROAP NEK2 CCNB1 TTK GINS1 KIF14 STIL CENPA GPI ESPL1 CDC6 NNT TYMS GLDC ORC1 CCNF CCT6A LILRB4 CCT2 NME1 LDHB HMMR KIF23 CHAF1A MKI67 TOP2A CCT5 CBX3 POLD2 KIF2C COASY RRM2 PRKDC MRPL3 KIF11 MCM3 LMNB1 AIMP2 ANG TOPBP1 MAD2L1 AHCY PSMD4 PFKP PHB IDH2 CASP6 CKS1B CBX5 CDK1 EXOSC2 UCK2 ATIC OAT TRAP1 KIF2A EZH2 DNAJC7 VBP1 CCNE1 TUBG1 DLGAP5 PSMA5 PSME2 KIF22 DTYMK GALNT3 ASNS CCT7 KLHDC3 BRD8 CDC20	up	**
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF	0.0000027	0.0000655	0.6272567	-0.2609951	-1.529471	423	SLPI EREG MEG8 LYPD5 USP12 GAPT LRRC8C PTPRE KCTD9 LRRFIP1 EGR2 BACH1 NEDD4L FOSL1 MYD88 TBC1D2 NEDD9 DENND2C IER2 AVPI1 ADAM17 SDE2 CSRP1 EIF5 HIPK3 KLF6 PTX3 RB1 ADRB2 TRAF6 SPRY2 ARHGEF2 HERC3 RHOB LDHAL6A MAP2K3 AGO4 SGTB BIRC2 KIAA0513 COQ10B ZFAND5 STK17B THBS1 ARNTL SOCS2 SOCS5 KLF7 FBXL3 EPGN LBH XCL2 MATN2 OXSR1 KBTBD4 CRIM1 AKIRIN1 TGFB2 RAB6A SRF BTG1 SLC25A25 AREG BCAR3 SGK1 NEK7 ADAMTSL2 RAB8B AQP3 SERPINB8 JUN LRCH1 SH3BP5 C20orf194 PLK3 FOXN2 WTAP ELOVL7 PTGER4 SKIL PNPLA8 HUNK ACKR3 PTGER2 HOMER1 GPRC5A SPRY4 CDK17 EHD1 KCTD10 TSC22D1 MIR23A IRS2 PIM1 CCDC68 LEKR1 ANKRD13A STK40 ANKRD12 ADAMTS15 ARPP19 LINC00319 JUND BMP2K ARAP2 PDLIM5 ABL2 WDR1 SERTAD1 IER5 PARM1 TIAM1 DDX59 ING2 RASSF8 B3GNT2 DUSP7 LYST CYTH1 LDLR NABP1 SHISA6 EHD4 RNH1 CNN2 ARFGAP3 PMAIP1 PIM3 ATP6V0A1 CTSH RNU6-433P KCNE1 ZNF800 SLC19A2 PRKCH ITGB1 SLC38A2 HAS2 ZFP36	down	***
REACTOME_TOLL_LIKE_RECEPTOR_TLR1_TLR2_CASCADE	0.0048820	0.0399308	0.4070179	-0.3252100	-1.528937	86	MYD88 MEF2A CD36 MAP3K8 TRAF6 MAP2K3 DUSP3 LY96 NFKB1 NKIRAS1 IRAK2 TLR4 SFTPD RPS6KA2 PPP2CA JUN CREB1 RPS6KA1 FOS UBB PELI1 MAPK8 PPP2CB TAB2 RIPK2 NFKBIA DUSP7 UBE2V1 DUSP6 ATF2 MAPK1 UBE2N HMGB1 MAP3K1 MAPK7 SKP1	down	*
SENESE_HDAC3_TARGETS_UP	0.0000028	0.0000675	0.6272567	-0.2607985	-1.528318	423	WEE1 CXCL3 CD55 ROBO4 CPEB2 LPXN PTPRB BMP2 CD44 TMOD3 CCDC88A BACH1 NEDD4L GTF2I INPP5A RBM14 OTUD4 TGFBR2 TRIB1 GGA2 DNAJB14 ATP2B1 NCEH1 MALAT1 GM2A BTG2 SPIRE1 KLF6 GLS PTX3 SLC7A11 ZNF697 SLAIN2 PPP3CA RB1 SLC25A37 SFRP1 AKT3 SPTBN1 MAPK8IP1 TFRC MCL1 RHOB PTPN12 TBC1D9 KCNMA1 SLC12A4 TNFSF15 TPP1 MYO1B ABCC4 ATF3 TLR4 CCND2 PLEKHB2 ELK3 SLC6A6 IL7R UBASH3B TBC1D4 IL24 USP16 AKIRIN1 ACTR2 BTG1 PDK4 CREBRF FMNL2 VAMP3 CREM PHTF2 SNAP23 RAB8B OASL SF3B1 CPEB4 SLC14A1 LTBP2 JAK1 MBNL2 IDS ATP13A3 GTDC1 CXCL5 YWHAZ TNFRSF10B GFPT2 CDK17 HIVEP2 PPTC7 PKIA TRAPPC10 SAV1 STRN ATP6V1A GALC MAP3K2 SOD2 KYNU GNA13 ADAM10 SERINC3 PDE4B CALB1 ETS2 SNHG16 MBNL1 CCL20 GEM CEP170 OPN3 CDKN1C ORMDL1 MEX3C PSME4 G3BP2 TRAF1 STK4 NFKBIA JMJD1C TIMP3 DOCK4 GRB10 IQGAP1 MAPKAP1 MIER3 PMAIP1	down	***
QI_PLASMACYTOMA_UP	0.0004215	0.0056485	0.4984931	-0.2805811	-1.524608	223	RBP4 IL17RB SWAP70 SNX10 LRRFIP1 LY86 TMOD3 MARCO CD22 FGR DNASE1L3 RNASE1 LCP1 RB1 CD37 ARRB1 EPOR CASP1 VASP STK17B CCL3 AXL ID2 CD53 ALOX5AP PLEK KLRD1 ACTG2 UBASH3B ARHGDIB ACTR2 HCK MTPN SRF BTG1 ARL6IP5 IL2RB RAC2 IFNGR1 WTAP SNX2 IRF8 GRB2 RPS6KA1 CAP1 CD7 RASSF2 CST7 MOB1A TGFB1 TFEB EHD1 GNB4 CCR1 ARAP2 IL18 IL18RAP LAT WDR1 SEMA4A CDC42EP3 SPIB UBE2D1 SP100 TRAF1 CD19 NFKBIA ABI3 KIT CD3G ANXA11 CNN2 IRF2 CNR2 CLEC4E ITGB1 ZYX NFAM1 PTGS1 BDKRB2 GNG11 DNAJB1 DAPP1 CD3E SLC43A3 IRF1 TRAT1 SH3BP2 ITGA6 CD4 CASP3 DUSP2 PLEKHO1 PLXNC1 ARAP1 FLT3 CAPG SLAMF1 DPP4 TUBB3 TLN1 PFN1 CD47 FGL2 PTPN1 STK10 ADCY7 HCLS1 CD3D LSP1 CCR5 BLK	down	**
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN	0.0000091	0.0001980	0.5933255	0.3052971	1.523355	561	PCSK6 DDX11 HELLS KIF20A GALNT14 MDM1 HJURP MCM10 BDH1 ELOVL6 DEPTOR ZDHHC4 GALNT6 NEK2 IGF2BP3 PAGR1 PTPRN2 ZFHX4 COA1 KIF18B IRS1 HILPDA NDUFS6 AP1S1 AURKB SIX1 SOX9 THTPA HOXB7 RAD54B FERMT1 ORC1 CCNF GALNT10 GINS4 MANSC1 TTLL4 DNPH1 EXO1 NUDT1 CISD1 PAQR4 MKI67 EMC9 KIF15 POLM CYP24A1 BUB1 FANCA TOP2A DPY19L1 AURKA ZNF112 APOL1 TMEM177 CARD10 VANGL1 POLA2 ATR ZNF174 MPHOSPH9 RRM2 TTLL12 RHOBTB3 MCM3 BLOC1S1 LMNB1 MCCC2 RNFT2 THYN1 CBY1 DCTPP1 THAP10 MRPS11 BRIP1 FNTB NAA40 RGS4 DET1 WWC1 PIGO SKP2 PSRC1 CKLF GEMIN4 PON2 ZNF512B ISOC2 CDKN2C IGFBP5 CDK1 WDR5B PPIC POLE2 BIRC5 C1orf112 POLR3K E2F1 ACP6 MCAT DNA2 NEIL3 SSX2IP COA4 ETFB TSPAN1 FOCAD FAM86C1 NRGN DGCR6 SNRNP25 CCNE1 FANCF SLC26A2 ADAM12 ATP6V0E2 ADAT1 LMNB2 UROS MRPS34 DHODH OSBPL3 SLC37A4 USB1 SPTSSA COPS7B PPOX DTYMK ZNF239 MSRB2 GINS2 PKP4 PRMT7 ENC1 CLTB CDC7 GEMIN6 DHRS1 USP18 HNF1B YLPM1 AP3M2 SLFN12 BCL2L1 MRPL24 BLCAP SURF2 POLR2I RNASET2 ALG8 FARSA PMS1 TM7SF3 CCNA2 PRIM1 ZNF93 MLXIP GTF3C2 PDF FKTN GBP1 WDR77 HK2 APBA2 N6AMT1 RSAD1 NME7 CDK5 AGBL5 WDR76 NUBPL TNS3 CHPF2 GMPR2 BRICD5 GGCX SEPHS1 FGFBP1 NNMT PNN UBTF NDUFB7 RRS1 ACSL5 FBXL18 TMCO6 ERLIN1 PARP2 C9orf40 CSTF1 MLLT11	up	***
ENK_UV_RESPONSE_EPIDERMIS_DN	0.0000034	0.0000813	0.6272567	-0.2575582	-1.523249	461	CLIC3 CD55 WNT4 EMP2 CYP4B1 LRRFIP1 THBD FYN MED4 CORO1C RTN3 FOSL1 EML1 INPP5A MSRA STX11 TGFBR3 GAS6 NFATC3 TRIB1 ARHGAP29 ANXA1 ATP2B1 UBL3 ASAH1 PLXNA2 C1orf21 MAP3K8 HSPB1 PBX3 PPP2R2A GATA3 PPP3CA TRAF6 NDEL1 SPRY2 TFRC RHOB GMEB1 MAP2K3 CFD PER3 CCL22 PTPN21 SAP30BP PLAUR ID3 KLF11 STK17B ARNTL BCHE ABCC4 SPAG9 CADM1 CXCL2 ATF3 PNRC1 DNTTIP2 SMAD7 MATN2 OXSR1 SMNDC1 TP53BP2 NCOA1 FOXN3 RPS6KA2 PKIG FRY TECR DCP1A SCEL ID4 PPP2CA AREG RYBP PNO1 UTRN AQP3 HECA DNASE2 DUSP8 RCAN1 PTGER4 CD83 IRF8 HERC1 GPR183 HOMER1 UVRAG TNFRSF10B ACSL1 PELI1 KLF2 HIVEP2 FOSB PKIA CHORDC1 TIMP2 VAV3 TCF4 DCK TESK2 FEM1B ZBTB11 GNAI1 IRS2 GALC PIM1 LGALS3 CRY1 GNA13 CSNK2A2 CLEC2B PDE4B CCL20 INTS6 RLF WDR1 OPN3 RAB5A CDKN1C ALDH2 EPHA2 SCPEP1 KPNA4 S100A4 NPAT KATNA1 KCNK7 KIT B3GNT2 CYTH1 RORA HEBP1 GSPT1 RSU1 ACAT1 MED17 UBAP1 PHYH EGR1 FJX1 CTSH ZBTB16 CHIC2 DUSP6 DKK3 NR4A2 PRKCH FAM8A1 FBXW2 TUBA1A EFS DNAJB4	down	***
SMID_BREAST_CANCER_LUMINAL_B_UP	0.0058717	0.0457230	0.4070179	0.3470747	1.521005	139	PCSK6 PTGES PTPRT DNAJC12 C17orf75 WFDC2 TOX3 NOVA1 SORD TFF3 IFT122 SLC27A2 NPIPB3 PCLO AGR2 CA12 TJP3 C9orf116 SPAG16 SERPINA3 MCCC2 SLC9A3R1 MRPS30 KRT18 ZNF652 CASC1 ARNT2 G6PC3 AGL TRIM9 SYT1 ESR1 RDH16 KDM4B ANXA9 TBC1D30 ZDHHC11 ALG8 CEACAM5 B9D1 TTC12 YBX2 SYBU	up	*
WANG_CISPLATIN_RESPONSE_AND_XPC_DN	0.0008563	0.0100072	0.4772708	-0.2813391	-1.520164	197	SLC31A2 GLIPR2 RAMP2 CDC42EP2 EIF4A1 CHMP1B KLF10 HIPK3 PRSS12 HLX STOM ARHGEF2 HERC3 FLI1 CYBRD1 SDCBP YBX3 SLC12A4 MYO1B CDKN1A KCNMB1 UBE2B TAF9 SMAD7 EFR3A MMP19 BTG1 ELF1 CDC40 EBAG9 JUN CELF1 RAC2 IFNGR1 WTAP FERMT2 TNFRSF10B ITGA11 DEDD GRSF1 RRAS TGIF1 VAMP4 CTNNAL1 GNAI1 PDLIM1 HBP1 CNTNAP1 PHF11 SESN1 ZNF143 NT5C2 ATP9B UBE2D1 SP100 CUL3 PRKG1 NRG1 TLK1 RNH1 DNAJA2 SLC35A1 CYBA KALRN FADS3 HAS2 CSNK1G3 PTGS1	down	*
KEGG_MAPK_SIGNALING_PATHWAY	0.0001728	0.0026212	0.5188481	-0.2784441	-1.515456	222	IL1A IL1B RAPGEF2 PLA2G10 BDNF FGF10 CDC42 MKNK1 TGFBR2 CACNA2D2 RAP1A RASGRP4 MAP3K8 HSPB1 NLK PPP3CA NR4A1 TRAF6 LAMTOR3 CRK AKT3 MAPK8IP1 PDGFA PPP3CC MAP2K3 ARRB1 DUSP3 NFKB1 DUSP1 TGFB2 SRF RPS6KA2 JUN RAC2 MAP4K4 HSPA1B DUSP8 GRB2 RPS6KA1 PRKACA FGFR4 FOS RRAS PRKCG MAPK8 FLNC TGFB1 DUSP5 MAP3K2 PPP3R1 JUND HSPA2 FGF2 ARRB2 TAB2 HSPA8 MAP3K4 STK4 PAK2 DUSP7 FGFR1 ATF4 CACNA2D3 CHP1 DUSP6 ATF2 MAPK1	down	**
REACTOME_ESR_MEDIATED_SIGNALING	0.0021976	0.0215504	0.4317077	-0.2918311	-1.512812	146	EREG GREB1 CAV1 HBEGF GNGT2 HSPB1 CAV2 GATA3 GNG7 AKT3 AGO4 AGO3 CDK9 CTSD EPGN GNAI2 NCOA1 SRF KANK1 AREG EBAG9 JUN PIK3R1 DDX5 CREB1 FOS CALM1 FOXO3 FOSB STRN GNAI1 GNG5 GNB4 KAT2B PPID JUND HSP90AA1 ZDHHC21 CREBBP GTF2F2 SPHK1 KAT5 CDKN1B ATF2 MAPK1 GNG11 POLR2L RAD21 EP300 POLR2B NR5A2	down	*
WELCSH_BRCA1_TARGETS_UP	0.0012304	0.0132880	0.4550599	-0.2848498	-1.512487	175	PTCRA CAT RDX LIPA INPP5K CITED2 GTF2I PRKAR1A NR3C1 CD9 ANXA1 PBX3 PICALM ANXA5 GATA3 UBE2D3 KRT4 SRSF5 LIMS1 YBX3 CDKN1A ID2 PPP2R5C TM9SF2 ADD1 RABGGTB HEXB RAB6A PRCP VAMP3 ID4 COPS2 PPP6C SRSF3 JAK1 CREB1 RAB8A RRAS AGPS MYL12A SERPINB1 GNAI1 NFYC FCGRT ZNF267 SERINC3	down	*
LAIHO_COLORECTAL_CANCER_SERRATED_UP	0.0026757	0.0249752	0.4317077	-0.3131621	-1.506684	106	SC5D DPYSL2 CAV1 ARL8B PRKAR1A VAPA ATP2B1 SPG21 ANXA5 SDCBP PLEKHB2 ELK3 EMP3 RBM34 RASSF2 TAGLN2 SNRK NDUFV2 PELI1 NOP10 RIN2 EMC7 TCF4 NPTN MACF1 ADAM10 ARPP19 BNIP3L PDLIM5 ARPC2 HSPA8 HNRNPC IQGAP1 EMC3 SVIL ATP1B1 HLA-DRB1 NXN CAPZA1	down	*
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP	0.0038859	0.0333659	0.4317077	-0.2976590	-1.504011	130	SEMA3G TMEM126A FABP4 PTPRB MMRN1 CAV1 CASP12 SBDS CLEC14A HDC LHX6 HNRNPDL SLC25A37 SDCBP AOC3 PRKD3 KLF9 LY96 CD300C MPC1 SPRYD7 USP16 MYO1C EBAG9 TYROBP CSTA RHOJ IFRD1 FAM177A1 CPA3 TEX30 NAB1 ACYP2 SERINC3 SESN1 SPARCL1 ARRB2 B3GALNT1 GIMAP5 DIXDC1 PLGRKT PTEN SPOPL ACAT1 SPPL2A TREM2 SLC26A11 PTGS1 PIAS2	down	*
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP	0.0013966	0.0148572	0.4550599	-0.2830676	-1.503024	175	GPD1 EPAS1 SECISBP2L CLEC3B LIPA HSD17B11 DDX6 QKI EIF3CL NFATC3 ZEB2 SH2B3 NFIX MALAT1 KCNK3 GM2A PRELP FZD4 MS4A1 STOM SIRPA TNS1 ARHGEF2 ITSN2 MAPK8IP1 EPB41L2 KIF1C SORBS1 PPP6R3 CCND2 SFTPD CRIM1 MYO1C PDCD6IP ZFP91 ETS1 PIK3R1 NDST1 IP6K1 EHD2 MAPK8 TIMP2 EHD1 CYGB APLP2 SOD2	down	*
BIDUS_METASTASIS_UP	0.0037530	0.0325273	0.4317077	0.3307169	1.502032	186	MCM10 FANCI CCNB1 CENPF PAIP1 PBK TTF2 DEPDC1 RACGAP1 CENPA ECT2 CDC6 TPX2 CCNB2 TYMS CAND1 BUB1 AURKA MPHOSPH9 RRM2 PRKDC WDHD1 FNDC5 KIF11 LMNB1 CHEK1 MAD2L1 KNSTRN NUSAP1 PLOD2 ASF1B CDK1 BIRC5 ANKRD54 GMNN FEN1 NF1 SRD5A1 VBP1 CDC23 DLGAP5 ADNP MNS1 SSRP1 P4HA1 CKAP5 KLHL23 EFHC1 GID8 SNRPD1 C5orf22 SRSF1 MARCKS TSR1 CCNA2 VDAC1 RFC5 TUBGCP4	up	*
BROWNE_HCMV_INFECTION_4HR_DN	0.0031965	0.0286491	0.4317077	0.3267365	1.501789	211	CCL19 CHEK2 UGT8 ZP3 SIX1 UMPS PMS2 GLB1L2 ZNF3 AVL9 SHC2 AP1G2 AURKA ODF2 POLD2 SETDB1 TOM1L1 EMG1 MORC2 NFYA XRCC1 RGS4 MNAT1 TFCP2 DYRK2 GTF2E1 METTL3 RALGPS1 ETFB ABCA4 ZNF623 PIAS3 SLC12A1 NMNAT2 GALK2 NINL PTGER1 ZNF239 SCN8A FZR1 LIN37 NOC2L TMEM186 DNMBP LTBR TMEM30B POLB ABCC10 RIN1 AP3M2 LRRC17 DDX23 ZNF749 KATNB1 ZNF274 PATZ1 B9D1 ADM ZNF195 SERPINI2 ZNF217 SOX12 MICU1 CDK5 SNUPN PARG TRIB2 ZNF205 RORC NDUFB7 RRS1 SLC1A7 NCAPH GEMIN2 ZNF629 CSTF1 MIOS CXorf40A SBF1 GSTT2	up	*
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK	0.0058115	0.0454465	0.4070179	-0.2945953	-1.498453	132	PPARG FABP4 LPL PLEKHF2 YPEL5 GINM1 PCYOX1 TTYH2 BFAR STOM FBXO8 ACSL3 FAM49B ABCC4 CD302 ADIPOR2 HSDL2 EFR3A BCAR3 IFNGR1 HSD17B12 PNPLA2 MSMO1 SORT1 CHPT1 AOX1 KAT2B PLA2G15 PCCA PUS10 TOB2 ALDH6A1 G3BP2 FDX1 ACADM MTUS1 LTBP3 CYTH1 TMCC3 NABP1 AFTPH PIM3 KLF15 CHP1 PXMP4 LIN52 DRAM2	down	*
ZHOU_INFLAMMATORY_RESPONSE_LPS_UP	0.0001843	0.0027499	0.5188481	-0.2680351	-1.497063	294	CXCL3 SEMA6A EREG HSPB7 ARHGAP31 DENND5A USP12 CD55 ZC3H12C IL1B RDX RAPGEF2 CD44 CCRL2 CLEC12B DDX6 NEDD4L FOSL1 UBE2FP1 IL23A DNASE1L3 TMPRSS6 ATP2B1 ADAM17 BTG2 RNF144B FZD4 LITAF PTX3 EIF4E LDHAL6A AGBL1 MAP2K3 CSRNP1 STAT5A SNAI1 PTPN21 LIMS1 KLF4 PLAUR DRAM1 NFKB1 C4orf33 NPAS3 CXCL2 IRAK2 AQP4 CCL4 HTT MAFF PRICKLE2-AS3 MOB3A KREMEN1 VWF SNN NINJ1 AXDND1 CD80 IL6 RBM34 OASL PNMA2 PPP1R15A WTAP ELOVL7 IRF8 OSM MAPK4 GRIA1 REL ACSL1 NIPAL4 ITGA9 TEC DUSP5 SLC24A1 GPR84 ADORA2A-AS1 N4BP2L2 CCL20 ICAM1 IL18 PDLIM5 ABL2 EPB41L5 NBN	down	**
MOOTHA_HUMAN_MITODB_6_2002	0.0005426	0.0068664	0.4772708	0.3077714	1.496642	358	CPS1 GPT AK4 BDH1 TSFM SLC25A21 GAL3ST1 MRPL46 NPIPB3 NDUFS6 TOMM34 ALDH18A1 NNT CYP27B1 SHMT2 MRPS35 COX11 NDUFB8 SDHA MRPL15 PCCB CYP24A1 NDUFS2 LARS2 MPO GCAT AKAP1 AMACR OAZ3 ABCB6 MRPS11 ETFA FDXR MRPS30 TST IDH2 SLC25A10 UQCR11 SSBP1 GOT2 OAT ACP6 TRAP1 MRPS2 SLC25A13 MRPL17 PDK1 MRPS12 ETFB MAST1 CPT1B UQCRFS1 ATP7B NFS1 SPG7 MTOR UROS MRPS34 LONP1 DHODH MRPL11 COX7C PPOX TK1 MRPL4 DAP3 NRF1 ACSL6 SLC1A3 COX10 TIMM13 BCL2L1 BAD MRPL24 MRPS33 CKMT2 HAX1 NDUFS7 AMT FARSA PYCR1 NME4 ABCF2 UQCRC1 HLCS COX5B OXCT1 ECHS1 MRPL9 NDUFA8 NDUFS8 CPOX TBCB VDAC3 MTHFD1 SBNO2 TIMM44 MRPS27 PDP1 BCAT2 MRPL20 MRPL48 NDUFB7 COX6B1 DNM1L TK2 COX17 ACAD8 CYP11A1 ACSL5 CYB5B TFB1M SARDH BCKDK POLRMT MRPS16 MLH3 UCP3 DGUOK MRPL12 CRAT CLPP OPA1 BAK1 MRPL2 TOMM40 TIMM10 MPST SHMT1 CS NDUFB2 TXN2 PC COX15 TIMM9 MCCC1 LYPLA2 MTHFD2 COX6A1 FIBP COX6C ABCB8 NDUFA9 SDHC MRPS7 ACADS MRPL35 MRPL13 GATM MRPL33 GSR NDUFA10 BCKDHA MFN1 SUCLG1	up	**
WANG_LMO4_TARGETS_DN	0.0001247	0.0019610	0.5188481	-0.2628348	-1.494650	318	RAB11FIP1 TUBD1 GATA2 CPEB2 U2AF1 RDX TMOD3 SAMHD1 LONRF1 TBC1D7 PLEKHA1 S1PR1 CDC42 FBXO3 PSMD5 USP47 PPM1D CLCF1 PTS CHMP1B BZW1 AHRR CSGALNACT2 SPTBN1 ATP6V1H RAB14 DIABLO SLC7A2 TBC1D9 DUSP3 SAP30BP ACSL3 RNFT1 MED6 ZNF24 UBQLN1 PLEKHB2 CAPZA2 RPF1 KBTBD4 SPRYD7 BACE1 LIN7A ACTR2 TOPORS MYLIP SYNPO2 SAR1A DDX20 JUN VAT1 OSTM1 EPC1 MPZL3 COBLL1 RBM22 AP3B1 SNX22 NOL7 GPRC5A ZNF407 MEAF6 OCIAD1 TMEM192 SLC3A2 RRN3 KRTCAP2 NECAB1 BCAS2 BAZ2B MTMR2 CDC37L1 C16orf72 EXOC1 PHF11 STX12 ATAD2B CHURC1 ELP2 SRP72 CYP2U1 NSUN4 FDX1 C17orf49 RASSF8 ZDHHC5 PAK2 FAM126B DLST ITCH IQGAP1 ZFAND2A PURB FEZ2 PAPSS2 RABGEF1 SUGT1 KAT5 MRPS28 KALRN HMGCS1 UBA6 SH3GLB1 RB1CC1 NUP88 SLC26A11 PPFIA1 WDR41 CHMP4A DAPP1 EXOC6	down	**
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7	0.0007300	0.0086857	0.4772708	0.3081012	1.494107	346	ALDH3B2 PRR15 PRLR FAM201A PTGES CDC45 PARPBP S100A2 CCDC34 SOX2 CYP2J2 COA1 DNAJC22 PHF14 TFF3 CREB3L4 C6orf141 E2F8 IFT122 HILPDA ASPM MMP1 TOMM34 SIX1 FIGNL1 ANKRD22 STC2 MCM4 PRKCA TYMS CA12 GALNT10 MIS18A B4GALT4 EPS8L1 TJP3 CLDN1 KIF15 IGF2BP2 RHNO1 HOMER3 MYO10 HOXC6 CMBL KIF11 FANCD2 LMNB1 MCCC2 THYN1 KIF3C RAD51AP1 MST1R TST MGLL GPX8 PLOD2 EPHA1 NCAPG STEAP1 SDCBP2 EZH2 SAPCD2 RECQL4 TSPAN1 RNASEH2A NET1 SNX27 ZNF233 GPR68 MNS1 S100A16 HMGN3 RBM12B FBXO4 DTYMK IL15RA GINS2 SAP30 FXYD3 ESR1 CEP128 HLA-A CLTB TCEA2 CDC7 CENPV CENPM WDR34 ENTPD3 ANXA9 ADD3 SRSF1 LRCH4 LRIG1 RCC1 HAUS4	up	**
PECE_MAMMARY_STEM_CELL_DN	0.0039126	0.0334908	0.4070179	-0.2994093	-1.491607	122	SRSF7 IDI1 EPB41L3 ACER3 CCNL1 TXNIP UBL3 ARHGEF2 TCF7L2 SNED1 MAP1LC3B PLBD1 SCAF4 EPS15 WASF3 TM9SF2 DEGS1 NSMAF DESI2 CTSZ GLUD1 JAK1 ZCCHC9 RNF146 CALM1 ZBTB1 TMEM230 PCM1 CDC16 SEC63 CUL3 JMJD1C RAB2B SFPQ CNOT8 PURB ITGB1 EBF1 HEY1 XRN2 NKTR RPP14 ANKH EMP1 DENND4C PUM2 REXO2 PNISR BTBD19 SQLE	down	*
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN	0.0033893	0.0301661	0.4317077	-0.2862901	-1.490735	154	LIMS2 DLC1 MBOAT2 CAV1 GTF2I HSPG2 ZNF385D PICALM KANK2 PTPN21 AHNAK NOSTRIN ACSL3 AOC3 ZCCHC24 NPR3 RIT1 CADM1 KCNMB1 ZBTB43 ACTG2 MRVI1 NCOA1 ZNF426 C20orf194 PDE5A MSRB3 RABGAP1 RCAN1 FERMT2 ZNF20 TMEM192 LMCD1 FLNC EPHA3 SORT1 SAV1 C1orf116 TGFB1I1 CD81 TAGLN CHMP3 RTN4 PARVA TTC28 COPS8 TIMP3 EMC3 CNN2 STARD13 ENDOD1 CX3CR1 MYH10 FBXW2 ZFYVE1 MTSS1 KIDINS220 SNRPN KATNAL1 DACT3 SEMA5A MAPK7 MYL9 MYLK EXTL2 PTPN14	down	*
REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2	0.0033743	0.0300965	0.4317077	-0.3070653	-1.485298	107	PECAM1 CLEC3B MMRN1 CTSW CD9 GAS6 CD36 ANXA5 SRGN PDGFA CFD THBS1 FAM49B ABCC4 SELP PLEK VWF TGFB2 PHACTR2 CYB5R1 CAP1 TAGLN2 CALM1 PRKCG STXBP3 TGFB1 TMX3 CDC37L1 APLP2 ORM2 ACTN2	down	*
YAMAZAKI_TCEB3_TARGETS_UP	0.0046771	0.0385981	0.4070179	-0.2840574	-1.484316	149	EPAS1 SEMA6A GREM2 RAMP2 THBD CDH5 RCOR1 PDE1B SOX17 BACH1 CITED2 SUSD2 HSPG2 SEMA6D PTPRM CYB561A3 NR4A1 SRGN TCF7L2 CST3 SNAI1 CASKIN2 PARVB ERP44 DOCK9 ID2 CCND2 LMBRD1 PTH1R FAM189A2 CTSZ MBNL2 COBLL1 RNF24 YPEL2 CALM1 GATA6 JUND YAF2 TFPI FDX1 GLUL KIT TIMP3 HSDL1 HERPUD1 KALRN GHR ITGB1 ZYX ATP1B1 SYCP3	down	*
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP	0.0000002	0.0000067	0.6901325	-0.2471769	-1.484152	657	RAB11FIP1 LPIN2 SLC12A6 TMEM52B OSBPL11 SECISBP2L CD55 CPEB2 C18orf32 DPYSL2 RAPGEF2 PTPRE LRRFIP1 TTC7B ARRDC4 FIG4 TMEM170B FYN INPP5K SEC22C PRAM1 GPCPD1 PLEKHA1 YPEL5 MEF2A BCL2A1 IL1RN EPB41L3 TXNIP NUMB EDEM1 KIAA0355 SH2B3 NCEH1 B3GNT5 HBEGF CHMP1B EIF1 CLEC7A EIF5 CSGALNACT2 KLF10 PAG1 SLC7A11 ADRB1 RBM4 MOB3C IL18R1 SLC25A37 PDE4D CD37 TAPT1 AGO4 MTMR6 ITPRIP SGTB EPOR BST1 ZSWIM6 KLF4 ZCCHC24 ITM2B KLF9 UHRF1BP1L MAP1LC3B MYO1B CLIC4 SCAF4 CCL3 SSH1 RIT1 CDKN1A C4orf33 ST7L PTPRC ATF3 CTBS RECK ARHGAP9 FCER1G ALOX5AP PLEK NUTM2A-AS1 HTT N4BP1 MAFF ANXA3 LIN7A NCOA1 HCK LACC1 BTG1 NINJ1 RBM39 TFAP2E TRAF3IP2-AS1 CTSS PHACTR2 PGD RAB8B UTRN HCST SEC14L1 HECA CD48 CPEB4 USO1 ETS1 TYROBP CCDC50 NXPE3 CSTA JAK1 PPP1R15A SKIL IFRD1 GLIPR1 PNPLA8 HSPA13 MBNL2 IDS SERPINB6 ENTPD4 FSD1L SUCNR1 OGFRL1 TNFRSF10B APH1B GAS6-AS1 RNF146 ACSL1 SLC3A2 SLC25A24 CDK17 AZI2 RBKS PKD2 MYL12A BIN2 TTBK2 CR1 TIMP2 EHD1 TCF4 DCAF5 SMCR8 SERPINB1 TGIF1 BAZ2B VAMP4 FPR2 SH3RF3 DUSP5 CNOT7 ATXN1 HBP1 GPR84 TAGAP GABARAPL1 PHF11 RGS2 VPS39 KAT2B MR1 ATAD2B HACE1 RNF2 BMP2K ARAP2 BNIP3L IL18 NEK1 IL18RAP CCDC69 SEMA4A ALDH6A1 SP100 DDX59 METTL7A PCBP1-AS1 NHLRC3 STK4 C7orf31 CCDC92 RET ADORA2A RAB2B FOXJ2 DNAJB9 KIF1B GRB10 NABP1 WDFY3 MIER3 ARFGAP3 TNFRSF10D PMAIP1 MED17	down	***
ONDER_CDH1_TARGETS_2_DN	0.0005211	0.0067069	0.4772708	0.3017193	1.474898	390	COL17A1 SAA1 TFPI2 CEACAM1 GPR87 PTPRZ1 TP63 CA9 PTGES HS3ST1 BIK GALNT14 KRT5 LAD1 EPN3 FAT2 S100A2 GALNT6 LCN2 SLC5A1 ABCA12 MMP1 KRT16 AKR1C1 PAK6 SOX9 CYP27B1 SPINT2 LSR CA12 FERMT1 XDH CYP4F11 PIP4K2C B4GALT4 KRT15 EPS8L1 ITGA2 CLDN1 FAM169A MAP7 KCNN4 LAMC2 STAP2 CBLC TRIM29 ITGB4 TMEM132A AKAP1 HOOK1 SERPINA3 FHOD3 AP1M2 SLC35G2 CD24 RIPK4 B3GNT3 SPINT1 MST1R BACE2 PERP EHF DDR1 INPP4B GRHL2 FLNB WWC1 PTPN3 MARK1 GRB14 KRT18 EPHA1 MCTP2 TNFRSF21 ESRP1 TNFRSF25 STEAP1 GJB3 CDH3 SLC12A8 ARTN SEMA3A TMEM51 IGSF3 TSPAN1 RAPGEF5 IRF6 ST14 CTSV PKP3 MAPK13 IL15RA S100A9 SPAG1 GALNT3 ELMO3 EPB41L4B FXYD3 TMEM30B SLC1A3 DHRS1 LIMA1 ERBB3 CXCL1 TFCP2L1 ERVMER34-1 KRT8 MYO5C LPCAT4 PTHLH CDCP1 OVOL2 ANK3 CORO2A EPCAM GNAL PRSS8	up	**
MIKKELSEN_NPC_ICP_WITH_H3K4ME3	0.0011594	0.0127762	0.4550599	0.3040588	1.474288	347	PLAT MEGF10 LYSMD1 ZMYND8 DNAJC12 SRGAP3 ZNF138 BRSK1 KIF14 FLAD1 TTC26 ALDOC ACY1 SMUG1 ZNF608 ZNF726 GOLPH3L TJP3 C5orf34 HMMR BBS1 CCDC77 EXOC4 GPER1 ZNF112 SMARCAL1 CSRNP3 RAD54L PHKG2 RAB13 SLITRK6 PML FBXO16 ALG3 OSBPL7 KCNJ2 RECQL5 TXLNB GPX8 CDKN2C MDH1B ZNF260 TTLL9 SYN3 TCTN2 BPGM SEMA3A WDR24 ZKSCAN5 SUSD4 ZNF454 MPI AKR1E2 COL1A1 DCLRE1C TRIM16 VPS41 TSNAXIP1 NMRAL1 ZMAT5 SLC37A4 ZNF239 STOML1 PCDH9 SYT1 MAPK10 FKBP14 ZNF416 NIF3L1 KLC4 GEMIN6 PTN PTER LSG1 LIMA1 PLD1 GMPPA ADAMTS12 MED24 RAI14 NSUN6 SRPK2 NOSIP SLC38A7 ZRANB3 ADD3 VCAM1 SPSB3 PYCR1 PRIM1 PRR11 ECH1 SCRG1 ZNF66 SCNM1 CTU1 PRPF31 ANK2 TOMM40L TRAK1 NME7 CPT1C GOSR1 ADCY6 NEIL1 FIS1 TMEM256 ZNF354B ZNF681 LRRC4C CLEC2D FAM222B NQO1 APOBEC3B SUMF2 CNPY4 CDHR4 ACSBG1 CXorf40A WDR63 HRAS ZC3HC1 NUDT22 SPRED3 ZNF276 CBLN3 BAK1	up	*
MIKKELSEN_ES_ICP_WITH_H3K4ME3	0.0001485	0.0022842	0.5188481	0.2948551	1.469523	542	UNC5CL PLAT CA9 KLC3 PTGES MEGF10 DNAH2 LYSMD1 ZMYND8 ARMC3 DNAJC12 WFDC2 CYP2J2 SRGAP3 CHRNG ZP3 ALDH1L1 BRSK1 SPP1 COL7A1 FLAD1 TTC26 GRB7 ALDOC ACY1 GLB1L2 COX6B2 SMUG1 GPX2 ZNF726 GOLPH3L TJP3 C5orf34 PLEKHG1 HMMR BBS1 PON3 C9orf116 TRIM29 CCDC77 EXOC4 TMEM184A MYBPC2 ZNF112 NCCRP1 SLC2A10 RAB19 SMARCAL1 HYDIN TMEM45A CSRNP3 EFCAB12 ADM2 RAD54L CCDC114 PHKG2 NME5 MORC2 RAB13 EHHADH PML FBXO16 ALG3 CLDN9 OSBPL7 RECQL5 TXLNB GPX8 RASSF6 NRSN2 PAK1 CROCC MDH1B ZNF260 TTLL9 GIPR TRIM2 SYN3 GJB3 TCTN2 BPGM ENPP3 FAM186A SEMA3A PBLD GDAP1L1 WDR24 ZKSCAN5 CPT1B QPRT PYROXD2 ZNF454 MPI SPEF1 AKR1E2 COL1A1 DCLRE1C TRIM16 VPS41 TSNAXIP1 NMRAL1 PKP3 ZMAT5 SLC37A4 FBXO15 C9orf152 ZNF239 STOML1 GBP6 SYT1 ELMO3 FKBP14 S100A13 ZNF416 IP6K2 TNK1 KLC4 GEMIN6 PTER LSG1 LIMA1 RIN1 ENTPD3 GMPPA GID8 MED24 RAI14 NSUN6 COL5A3 NOSIP SLC38A7 ZRANB3 C1orf56 ADD3 CYP2D6 EFHB NFE2 NHSL1 ANK3 SH3TC2 MVP SPSB3 AKAP6 PRSS8 PYCR1 AGMAT RCN3 PRIM1 PRR11 TTC12 ECH1 FLRT1 ZNF66 SCNM1 TMEM141 CTU1 PRPF31 ANK2 TOMM40L TEPP TRAK1 WDR49 NME7 FAM83E CPT1C GOSR1 SCN9A ZNF205 NEIL1 PCBD1 FIS1 TMEM256 ZNF681 KRT17 PLIN3 CLEC2D FAM222B ARHGAP8 ACSL5 NQO1 CD38 APOBEC3B SUMF2 CNPY4 ZNF740 TMEM63C CXorf40A WDR63 C7orf25 HRAS MST1 GSTP1 CNKSR1 ZC3HC1 NUDT22 SPRED3 ZNF276	up	**
MCCABE_BOUND_BY_HOXC6	0.0015407	0.0160800	0.4550599	0.3052043	1.467377	307	KIF12 LEMD1 MEGF10 CHST6 ZNF84 PPIP5K1 NOXRED1 PGM2L1 CREB3L4 ZFHX2 E2F8 KIF14 NPIPB3 PMS2P5 ALDH18A1 DIO2 GLB1L3 ARHGAP33 COCH TMEM132D LIG3 ASXL3 AK8 CLPTM1L BTRC C19orf48 ZFYVE27 TIGD4 BPIFB1 THBS4 C20orf96 CXCR5 MAP1LC3C WDHD1 HOXC6 SGPL1 SERPINA3 BLOC1S1 ZNF785 AP1M2 CGB7 ORC6 RAD51AP1 PTGDR2 EDN2 RBAK FRMD5 FRMPD2 CBX5 PAK1 STON2 BCAS4 PICK1 PKD1P1 ZNF541 SNAPC1 DNAH5 FER1L4 CBFA2T2 WDR86 SUSD4 RP9 SPEF1 CCDC151 DHODH MRPL52 RBM12B ZNF239 GAS2 GUSBP1 DNMBP TMEM30B SLC1A3 ZCCHC17 CHTF8 PIGU CD2BP2 VCAM1 PTHLH SKAP1 LRRK1 TTLL6 CDH11 GADD45G KRTAP5-9 DBNL SHCBP1 TUBGCP4 TNKS1BP1 FARSB ZSCAN29 RHOD SCN9A SBNO2 SLC36A1 ERRFI1 NUP210 DPP10 SLC39A1 CCDC91	up	*
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	0.0000365	0.0006741	0.5573322	-0.2426234	-1.459099	497	WEE1 RBP4 SWAP70 TEK FABP4 CAT SLC16A4 PTP4A2 DPYSL2 LRRFIP1 FYN CD44 KIAA1109 CITED2 QKI CYB5R3 GTF2I DYRK1A PRKAR1A CD9 CYP4A11 TGFBR2 RHOA ZEB2 HSPE1 NDUFAF1 BZW1 SERINC1 PICALM ANXA5 LITAF GLS FOXJ3 TOR1AIP1 RB1 TMEM123 SRSF2 HNRNPDL SFRP1 ZEB1 SRGN MCL1 ATP6V1B2 PTPN12 EVI2B HMGN1 DUSP3 SCP2 SDCBP ACSL3 LEPROTL1 ROCK1 TMED5 MYO1B SEC24B NR1D2 PTPRC VIM PAPSS1 ID2 EPS15 PIK3C2A ZMPSTE24 PPP2R5C DSTN N4BP1 IL7R MYH11 PAFAH1B1 HLA-DQA1 AFF1 RSRC2 PTH1R ACTR2 SIAH1 TOPORS ETF1 PRKRA COPS2 NEK7 NXF1 VAT1 DESI2 C11orf58 CYCS DNAJA1 SHOC2 IFNGR1 RCAN1 GSTO1 SNX2 SP3 HSPA13 DDX5 SELENBP1 CREB1 RAB8A CRYM MORC3 CDK14 MSMO1 CD74 AZIN1 PPP2CB NUP153 HNRNPA2B1 PHF3 NDUFA5 DPM1 TSC22D1 ATP6V1A GALC APLP2 TOB1 NPTN CLASP2 SERINC3 PPID TSPO AMD1 BMP2K EIF3F RBL2 PDLIM5 NBN SPARCL1 TFPI SRP72 TRAPPC8 HSPA8 MEGF9 HNRNPK CREBBP HNRNPC ARPC5 GRB10 DUT WDFY3 PUM1 RAB2A LYZ HAT1 ARHGEF18 ABI1 HERPUD1 SAP18 HIPK1 ATF2 CX3CR1 MYH10 DYNC1I2 TUBA1A CBR4 SRSF11 HLA-DRB1 UBE2N SCAF11 CAPZA1 SERP1 NMI DLD ATP8A1 SNRPN FNDC3A WWTR1 SH3BGR	down	***
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	0.0000004	0.0000108	0.6749629	-0.2347625	-1.458236	800	SMAD6 SASH1 SWAP70 DLC1 DENND5A USP12 SECISBP2L ADCY9 RDX RAPGEF2 MBOAT2 LRRFIP1 RCOR1 BDNF FYN KIAA1109 GTF2E2 QKI SRSF7 DYRK1A MEF2A NR3C1 TGFBR3 WBP4 OTUD4 TGFBR2 NFATC3 RFTN1 HEG1 ZEB2 NUMB ARHGAP29 KIAA0355 ATP2B1 PTPRM UBL3 ADAM17 RAP1A PBX3 PICALM REV3L KLF10 KLF6 CAV2 PTX3 EIF4E PPP2R2A FOXJ3 RB1 HNRNPDL ZFYVE16 ZEB1 ITSN2 TCF7L2 UBE2D3 ATP6V1H SETD3 TIPARP ZMIZ1 ADARB1 PTPN12 ROCK2 TLE4 ACSL3 PLAUR ID3 ROCK1 GRK5 SOCS5 KLF7 MYO1B GAPVD1 SPAG9 SEC24B PDE8A NFKB1 DOCK9 RBMS1 CDS2 EPS15 CCSER2 WASF3 DUSP1 PIK3C2A SMAD7 MBD2 PPP2R5C PPP2R5A GNAQ OXSR1 N4BP1 IL7R PAFAH1B1 KPNA3 TP53BP2 AFF1 CRIM1 MARK3 EFR3A NCOA1 TGFB2 STK24 TDRD7 FOXN3 RAB6A RPS6KA2 RBM39 MOB4 RBPJ PPP2CA RYBP BCAR3 NSMAF NEK7 PIKFYVE SEC14L1 SRSF3 C2CD2 JUN MITF RAB31 MN1 DDX17 ARHGEF10 SHOC2 RABGAP1 APBB2 FERMT2 DHX15 IPO7 SNX2 PODXL IFRD1 SP3 ZNF804A FRYL CREB1 MALT1 ATP13A3 HOMER1 AP3B1 UVRAG DLEU2 TUBGCP3 WDR7 AGFG1 SLC25A24 CDK17 HIVEP2 YTHDF3 USP7 FOXO3 PKD2 MAPK8 RIN2 SPOP AZIN1 NUP153 STXBP3 PHF3 TGIF1 PDS5B BAZ2B ZFYVE9 DUSP5 ZBTB11 GNAI1 PIK3C3 NFYC ATXN1 ORC2 PPP3R1 HNRNPH3 CTIF CLASP2 CRY1 MACF1 N4BP2L2 ADAM10 PHLPP2 ME2 MBNL1 ATAD2B PCCA HELZ RNF2 BMP2K ARAP2 ANKLE2 FGF2 NEK1 PDLIM5 TNFAIP8 RLF YAF2 CEP170 CDC16 NBN TFPI NT5C2 ACAP2 TIAM1 PIP4K2A TRAPPC8 EPHA4 TAB2 SIK3 ARIH1 SP100 PSME4 NUP98 CREBBP DAPK1 MAP3K4 NPAT TTC28 GTF2F2 PTEN TMEM87A TLK2 CYTH1 CAMSAP2 ITCH LDLR DOCK4 NRG1 TLK1 WDFY3 PUM1 NUP160 SMAD4 RNF13 EVI5 DMXL2 KLC1 HAT1 ABI1 SETX STARD13 UBR2 SERPINE1 PEX14 CDKN1B CLIP1 ATP11B CENPC ATF2 LHFPL2 CLOCK	down	***
MILI_PSEUDOPODIA_HAPTOTAXIS_UP	0.0001306	0.0020488	0.5188481	-0.2467612	-1.451780	435	MRPS18C MNDA PTP4A2 NUP54 TXNL1 QKI CYB5R3 IDI1 MEF2A NR3C1 AGTPBP1 WBP4 RBM7 UBR3 STARD4 TRA2B RAP1A BZW1 ZDHHC2 SERPINB9 PPP3CA KANK2 ZEB1 UBE2D3 EXOSC9 KIF1C MTMR6 SCP2 HNRNPA3 LIMS1 ROCK1 ATP6V1D ZNF24 CCND2 SS18L2 CAPZA2 PIK3C2A PAFAH1B1 BCLAF1 KPNA3 USP16 EFR3A TAF13 ACTR2 TOPORS SACM1L MTPN GPBP1 MOB4 RYBP ASNSD1 COPS2 PNO1 RBM34 SNAP23 RAB8B RWDD1 SRSF3 SF3B1 DNAJA1 TBC1D12 FYTTD1 MBNL2 OGFRL1 NAA30 CELF2 AGFG1 CACYBP PTP4A1 YTHDF3 MAPK8 CHPT1 PBRM1 STRN DCAF5 KCTD10 CRYZL1 VAMP4 SBF2 YTHDF2 RPL21 CNOT7 ORC2 SLIRP HNRNPH3 MBNL1 ARPP19 CCNH RNF138 C3orf38 YAF2 CTTNBP2NL RAB5A PIP4K2A CYB5R4 VPS4B TRAPPC8 DIXDC1 HNRNPK COMMD8 CUL3 TLK2 CAMSAP2 PSMD6 FAM13B NAA15 GSPT1 EIF4G2 PPP1CB ZNF326 YTHDC1 PSIP1 TSTD3 CFL2 HMGCS1 ATF2 CRBN SSB CLOCK SH3GLB1 FBXW2 FAR1 CSNK1G3 DNAJB4 PPWD1 SYCP3 YWHAB SRSF11 PPFIA1 CAPZA1 MATR3 ESCO1 CUL2 CRIPT FNDC3A WWTR1 WDR26 SLU7 BBIP1 SREK1IP1 UFSP2 CCNC PJA2 SKP1 BTBD1 MYO5A LARP7 MRPS14 IVNS1ABP UBE2D2 AP4S1 GNL2 SUCLA2 AASDHPPT TANK EIF3J	down	**
ZHANG_BREAST_CANCER_PROGENITORS_UP	0.0007741	0.0091323	0.4772708	0.2968845	1.451520	391	TRIP13 TP63 HELLS BUB1B NUP107 PROM1 CENPF CPSF6 PBK TTF2 PHF14 DEPDC1 BRCA1 BET1 CDCA7 ANLN CDCA8 ECT2 CDC6 FIGNL1 RBBP8 UHRF1 MCM2 CDC25A CA12 NCAPD2 LSM5 ITGA2 MELK CEP55 TP53BP1 BUB1 TOP2A AURKA NUP155 WDR3 ATR KIF2C CD2AP RRM2 TRRAP HOOK1 GPSM2 PFN2 CD24 TOPBP1 CHEK1 DNAJC9 ACTL6A AHCY DDR1 GRHL2 TULP3 SKP2 PARP1 TNIK SSBP1 SERTAD4 C1orf112 GMNN POLR3K UNG NCAPG PRR14L ENPP3 PSAT1 ANKRD26 PDK1 EZH2 POLR1C ACTR3B ARNT2 FGFR1OP RNF44 EFTUD2 VBP1 CEP192 TRIM37 C1orf131 ZNF239 ESCO2 ANP32E PKP4 TCEA1 EDARADD SAP30 ANAPC1 NUP85 PLEKHB1 CLDN12 GEMIN6 EFCAB7 RPA1 ZNF160 MRPS33 LSM7 EDAR ATAD2 PATZ1 GTPBP10 STRBP CCNA2 PRIM1 TMEM117 VDAC1 SHCBP1 CEP164 RAD51 FARSB OXCT1 RPRD2 NME7 RNF7 VDAC3 SMC2 MTHFD1 PAICS TTC9C NCAPD3 ARMC10 PWP1 ZC3HAV1L E2F7 TAX1BP1 ZNF367 LMBRD2 CD38 VPS26B PDZD8 AKAP9 RBL1 TRPS1 TMPO MPZL1 CRYZ TASP1 PABPC4L MLLT3 SLC20A2 SHMT1 TRIM59 ZNF532 POT1 GLRB XRCC5 NAE1 C1orf74 PPP2R1A NUDCD1 ORC5 POLD3 SMC4 METTL9 STMN1 IK HNRNPA1 SKA2 LRBA TTC3	up	**
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	0.0004242	0.0056704	0.4984931	-0.2549054	-1.447393	327	AKAP5 MS4A7 PHACTR1 CD55 PDE1B STXBP6 SOX17 GFOD1 LDB2 LONRF1 RXFP1 NEDD9 TGFBR2 FAM49A KCNAB1 ATP2B1 NFIX STARD9 LMNA REV3L KLF10 FOXP1 ANPEP PEX5L FOXJ3 ZEB1 SOX7 ZSWIM6 ST3GAL2 RUNX1T1 CDIP1 PRKD3 DAB2 THBS1 KLF7 C1QTNF7 PER2 C9orf72 PAPSS1 PTGER3 CD300C INHBA PTCHD4 MATN2 ADAMTS8 UBASH3B NRROS SERTAD2 TSPAN18 RBPJ ID4 CHDH RYBP SYNPO2 PKNOX1 SLCO2B1 CABLES1 C1QA SH3BP5 RHOBTB2 SLC14A1 BMP3 BTD TYROBP CSTA RHOJ CD83 GYPC MFAP4 RTN4R ENTPD4 GRIA1 RASSF2 GAS2L3 CTTNBP2 HIVEP2 PKD2 ZNF521 TCF4 FEM1B SKIDA1 TGFB1I1 MCUR1 C8orf37 MEIS1 MRGPRF JUND BMP2K SPARCL1 PAMR1 PARM1 CDC42EP3 DIXDC1 GRIN3A RBMS3 BCAT1 PTEN DUSP7	down	**
PLASARI_TGFB1_TARGETS_10HR_UP	0.0034251	0.0303048	0.4317077	-0.2722271	-1.445464	175	EREG OTUD7A OLR1 KLF13 LRRC8C PRKG2 GREM2 LRRFIP1 EGR2 GFOD1 FOSL1 ABCB1 IER2 HBEGF ITGA5 IL18R1 PDGFA FOXC2 CNN1 CSRNP1 SNAI1 NRARP PLAUR NES ARNTL SOCS2 ARC INHBA MAFF HCK WNT9A FLT1 RNF149 IL6 PLK3 JUNB PPP1R15A PI4K2B FSTL3 GFPT2 IP6K1 MCAM WNT11 TGFB1 DUSP5 GPR84 CRY1 CCL20 HSPA2 FGF2 TIMP3 TMCC3 PMAIP1 SPATA13 PAPSS2 SPHK1 SERPINE1 FJX1 DUSP6 ENDOD1	down	*
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	0.0001177	0.0018831	0.5384341	0.2873050	1.443772	636	HMGA2 ONECUT2 LINC00342 FOXM1 NXPH4 AK4 GPT2 ELOVL6 TFAP2A S100A2 BUB1B NUP107 NEK2 CCNB1 CENPF IGF2BP3 PSPH SLC2A1 NDC80 PRIM2 DEPDC1 SIX4 ZNF138 TTK RACGAP1 KIF14 ANLN ASPM STIL COL7A1 NUF2 AURKB CENPA ECT2 TPX2 TRIB3 FIGNL1 STC2 RBBP8 MCM4 HOXB7 MCM2 HPS3 CCT6A MCM8 MIS18A SRPK1 SHMT2 MOCOS XPOT CCT2 TNC C5orf34 CLDN1 MELK HMMR DLG1 CEP55 SYTL2 GFPT1 SLFN5 DCBLD2 IGF2BP2 TPBG EEF1E1 TOP2A AURKA CBX3 ATR TPR MCM7 RSRC1 RHOBTB3 WDHD1 ZNF146 KIF11 LINC00511 SP140L EGFR POLR3C TOPBP1 CHEK1 ORC6 ACTL6A MAD2L1 RAD51AP1 MRPS30 RBAK MIPOL1 GPX8 FRMD5 NUSAP1 CDK1 DNTTIP1 UCK2 AP3D1 ULBP2 KIF2A PSAT1 PEG10 FEN1 SSX2IP LINC00958 SEMA3A NLN DIAPH3 DNMT1 CEP63 WDR53 C3orf80 PSMA5 TRIO HECTD1 PDRG1 LINC00662 KIF20B ASNS GFM2 TM9SF4 ANAPC1 AHNAK2 TWF1 CCZ1 ENC1 RAD50 SUPT16H CKAP5 CDC20 ZNF616 FAF1 FBXO22 BCL2L1 CXCL1 ZNF780B ZNF160 CKAP2 XRCC4 ANKRD1 HAUS6 DYNC2H1 RCC1 SLC1A5 GAD1 ATAD2 GTPBP10 PMS1 PRR11 STK38 NBPF14 DENR GTPBP2 HK2 OSBPL10 ZWILCH ARHGAP5 COPA ARHGAP11A ZNF700 ZMYND19 NME7 ACP1 TTC39C ZNF131 SMC2 ZNF567 LIF ZNF91 CENPE EIF4G1 ADRM1 PFDN4 DDX52 DNAJC10 CELSR3 TRUB1 PAICS UBE2C PNN FBXO45 KRT80 ENO1 E2F7 DNM1L ZNF367 PPP1R14B CALU BRIX1 IFI16 ERLIN1 SNAP25	up	**
MIKKELSEN_MEF_HCP_WITH_H3K27ME3	0.0027134	0.0251780	0.4317077	0.2991560	1.440768	315	SLC9A3 KIF12 PRLR ONECUT2 B3GALT5 SLC5A5 PTPRT CPLX2 SPOCK1 LAD1 SLC13A3 GALNT6 DOC2A UGT8 SOX2 PTPRN2 JPH3 NPAS1 DNAJC22 SLC5A1 SLC27A2 FGF11 CD164L2 LAMP5 GRIN2A KCNT1 CYP27B1 LSR GRHL3 IGFBPL1 CNNM1 RUNDC3A MARVELD3 FSTL4 DPYS SLC6A20 LAMC2 CBLC CYP24A1 THBS4 TTC22 FNDC5 RSPO4 SNHG11 AP1M2 PROM2 SLC45A1 OXTR GRHL2 IGSF21 NRTN PRRT3 DMGDH SRCIN1 TCF20 SCTR LRRC9 SPAG6 PACSIN1 SLC35F3 GPRIN1 RAB11FIP4 TCTE1 MAST1 IRF6 RBFOX3 KY SALL4 KCNC3 SCN8A SPTBN2 GRIN3B ECEL1 CHD5 ACSL6 NAGS CADM3 KCNB1 NRXN2 SLC6A1 MYO5C CELF4 ODF3B CABP7 BSN CHRNA3 MMP24 STMN3 SKAP1 CDCP1 GAD1 HTRA3 CNTN2 DOK7	up	*
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP	0.0018215	0.0183311	0.4550599	-0.2622289	-1.438855	228	SC5D GATA2 PTPRE CD44 CAV1 YPEL5 HMGCR KCNN3 NR3C1 CD9 FAM49A HEG1 TMX4 ARHGAP29 CSRP1 CAV2 TCF7L2 CD58 RHOB CYBRD1 FABP5 TBC1D9 ARRB1 FOXO1 KLF4 ITM2B ID3 OSTF1 THBS1 MAP1LC3B BCHE SOCS2 CADM1 ID2 CCND2 M6PR DUSP1 ELK3 INHBA HES1 MAFF ADD1 SERTAD2 CREM SGK1 PHACTR2 AQP3 JUN SH3BP5 MN1 MAP4K4 JAK1 ACKR3 CAP1 FGFR4 PELI1 MME EPHA3 VAV3 PEA15 TGIF1 TGFB1I1 IRS2 PCDH17 LTBP1 ADAM10 TCF7L1 PCCA TXNDC15 CXCR4 CUL3 CTSC MMD THEMIS2 NRP2 HEBP1 CREG1	down	*
MARTENS_BOUND_BY_PML_RARA_FUSION	0.0001802	0.0027106	0.5188481	-0.2458136	-1.435877	406	AJAP1 RAB11FIP1 ACP5 PEBP4 HMOX1 FCN1 KLF13 SPN PGC SIK1 LYL1 LMO2 GFOD1 C5AR1 NUDT9 FRAT1 FGR LINC00311 UBL3 LATS2 SDE2 NMUR1 SIRPA SPTBN1 TMEM41B ARHGEF2 SPI1 CD58 ZMIZ1 MAP2K3 ARRB1 ST3GAL2 VASP DENND3 CDK9 GRK5 CTSD LAPTM5 COTL1 P2RY2 CDS2 ID2 MIR24-2 ALOX5AP PLEK INHBA SLC6A6 RSL24D1 UBASH3B MRVI1 RSRC2 KREMEN1 STK24 HCK NINJ1 RPS6KA2 PKIG WNT9A RNF149 PGD MAML2 RWDD1 RAB31 RAC2 MN1 TYROBP RPL9 AK1 RAPGEF1 DAPK2 IRF8 DDX5 RPS6KA1 NUDT15 TNFRSF10B TAGLN2 ZNF683 TPRA1 CELF2 MCAM ACSL1 PLCG2 KLF2 CD164 HIVEP2 MBP RUNX3 SLC7A5P1 FOSB PIK3AP1 FXYD6 TIMP2 DOK3 SERPINB1 HECW1 YTHDF2 MIR23A DUSP5 GALC ATP6V0C APLP2 FCGRT	down	**
UDAYAKUMAR_MED1_TARGETS_DN	0.0030277	0.0273586	0.4317077	-0.2627351	-1.434200	211	HSPB7 HMOX1 ADCY9 FOLR1 THAP9-AS1 NEDD4L CITED2 DYRK1A PPM1D TRIB1 SPCS3 PDE2A TXNIP ADAM17 LIFR PPP3CA KANK2 RHOB EFCAB14 HNRNPA3 KLF4 PXDC1 MAP1LC3B DENND3 GRK5 SPAG9 TMBIM1 CDKN1A NR1D2 ATF3 AXL ID2 ARL4A VCPKMT BTG1 TRGC2 RYBP CREM MN1 JUNB RCAN1 IFRD1 ACKR3 HERC1 EHD1 PEA15 DUSP5 PIM1 HBP1 MEIS1 GABARAPL1 ACYP2 RGS2 CLEC2B ETS2 INTS6 TFPI CDKN1C TIMP3 PTEN TMEM87A DNAJB9 TNFSF9 FAM13B RNF13	down	*
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN	0.0022095	0.0215903	0.4317077	-0.2643565	-1.431531	203	SLC31A2 HHEX LRRFIP1 CITED2 GTF2I PRKAR1A ENTPD1 ABCG1 SLC19A1 TCAP FLI1 FOXO1 ROCK1 PDE3B VIM ZMPSTE24 GCA GNAQ GNAI2 CALM2 ARHGDIB NCOA1 STK24 PRCP SLC25A3 S1PR4 SNAP23 SEC14L1 CSTA JAK1 DAPK2 IDS RPS6KA1 CELF2 PLCG2 CALM1 NUP153 TGFB1 SRSF4 CBFA2T3 TOB1 RGS2 ADAM10 ME2 GTF2B RBL2 SELPLG FKBP1A CREBBP ICAM3 CYTH1 ANXA11 IQGAP1 FEZ2 EIF4G2 KLC1 TBPL1 CAPZB	down	*
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL	0.0042380	0.0358861	0.4070179	0.3004336	1.431386	284	ALDH3B2 PRLR KIF20A AK4 GABRP ZMYND8 S100A2 PROM1 CYP2J2 KIF18B PKP1 CLGN SPDEF GINS1 PRR15L KIF14 ABCA12 PCLO STIL KRT16 E2F3 RBBP8 TYMS MYL6B LDHB MELK KIF23 CEP55 BBS1 MKI67 IGF2BP2 MSX2 TOP2A SLC2A10 ABCC5 TTLL12 TRPV6 PDCD5 AMACR KIF11 YEATS2 SIDT1 SLC9A3R1 FBL ZKSCAN1 ETFA RABEP2 INPP4B IDH2 PON2 KRT18 PPIC TNFRSF21 NAV2 EGF ETFB DAP SERHL2 FAH LRRC8D TP53TG1 ANP32E ENOSF1 S100A13 PLEKHB1 GALNT7 P4HA1 TSTA3 LIMA1 CDC20 STOML2	up	*
GABRIELY_MIR21_TARGETS	0.0012323	0.0132880	0.4550599	-0.2601486	-1.429585	258	SASH1 OLR1 SOWAHC KLHL8 BMPR2 GTF2I FBXO3 USP47 TGFBR2 UBR3 WWC2 RRAGC B3GNT5 TACC1 LIFR REV3L PAG1 ITSN2 CYP4V2 ZYG11B FBXL5 CYBRD1 AGO4 PER3 LIN7C ZADH2 GAPVD1 MGAT4A TLR4 RECK PIK3C2A CLIP4 GNAQ PRICKLE2 RUFY3 ACTR2 TGFB2 FAM102B FOXN3 SACM1L MTPN SPIN1 PHACTR2 NEK7 UTRN JPH1 RABGAP1 FERMT2 FBXO11 PIK3R1 COBLL1 NAA30 PELI1 USP7 PKD2 BTBD7 PBRM1 DDHD2 ZRANB1 MAP3K2 MEIS1 ATAD2B SESN1 NEK1 SLC31A1 SEC63 OSR1 B3GALNT1 ACAP2 EPHA4 MEGF9 LIMCH1 CUL3 TIMP3 DOCK10 RNF38 PURB ZBTB44 FNBP1 ZNF326 ATP11B ATF2 CLOCK EXOC8 SRSF11 VPS36 TRPM7 WNT5A SCAF11 ARHGEF12 ATP2B4 MAP3K1	down	*
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN	0.0014242	0.0150918	0.4550599	-0.2594361	-1.420579	224	RBP4 PHACTR1 FABP4 SMIM12 SAMHD1 CRY2 PRPF38A FUCA1 SCARF1 DDO TXNIP RRAGC CES1 MAPK8IP1 CST3 AGO4 CFD SCP2 PPM1K LIN7C AOC3 ITM2B FAM76A AFAP1L1 PER2 CDS2 IRAK2 ZBTB43 ZMPSTE24 PINK1 PRICKLE2 PEF1 BTG1 RBM39 CDC40 INPP5B NOTCH1 SH3BP5 LTBP2 RPS6KA1 CASZ1 EPC2 ACSL1 MBP DDHD2 TCF4 SRSF4 SMCR8 ZFYVE9 CPT2 TOB1 SERINC3 RXRA ELOVL1 CDC42EP3 TAB2 TOB2 SP100 EPHA2 TRAF1 SKI PUM1 USP48 ZBTB40 CBX7 HERPUD1 PHYH KLF15 GGT6 C5AR2 ZBTB8OS HP1BP3 HEY1 MUL1 DNAJC8 C11orf54 GABPB1 RPA2 SLC23A2 DUOXA1	down	*
MULLIGHAN_MLL_SIGNATURE_1_UP	0.0005100	0.0066097	0.4772708	-0.2486362	-1.419789	334	SIRPB1 PECAM1 CLEC3B SNX10 CAT ADCY9 IL1RN FUCA1 LAMP1 PILRA DPEP2 SPG21 PBX3 LCP1 DACH1 TOR1AIP1 SIRPA ADRB2 GRN HNRNPU SPI1 ADARB1 EVI2B CASP1 PTAFR FUT7 MVB12B CEBPA TPP1 LAPTM5 PER2 PMM1 ITGAX RRP8 ID2 CD302 RECK M6PR CD300C EVI2A ACTR2 TDRD7 HEXB RAB6A SRF ARL6IP5 PSEN1 SERPINB8 RAC2 MTMR9 CSTA RCAN1 IRF8 SDHD GRB2 MALT1 SNX1 RPS6KA1 TNFRSF10B RASSF2 CLN3 CALM1 TNFSF13 RBKS ATG3 TREX1 NKG7 TRAPPC10 FXYD6 TFEB MEIS1 CCR1 THAP11 PPID MR1 MBNL1 RXRA PITPNA SELPLG ARPC2 IQSEC1 CDC42EP3 CXCR4 NLRP3 SCPEP1 S100A4 COMMD8 JMJD1C DUSP7 LYST ABCA8 CCND3	down	**
PASINI_SUZ12_TARGETS_DN	0.0007115	0.0085024	0.4772708	-0.2548855	-1.418825	277	MEG8 GLIPR2 WNT4 DPYSL2 LRRFIP1 BMP2 BDNF DDX6 CAV1 CORO1C MYADM RTN3 CITED2 IDI1 TRIB1 ANXA1 BMP1 HBEGF MALAT1 CSRP1 BTG2 ANXA5 FOXP1 KLF6 CAV2 SERPINB9 TMEM123 TUBB6 CNN1 RHOB PTPN12 AMOTL1 AHNAK NPNT BNIP2 THBS1 KLF7 TMBIM1 CDKN1A RBMS1 VIM AXL ID2 ARAP3 DUSP1 ANXA3 TGFB2 MTPN MYO1C JUN VAT1 LIMD1 ETS1 SKIL CAP1 GPRC5A CD151 SLC25A24 PKIA FLNC TIMP2 PEA15 KCTD10 TGFB1I1 IRS2 TAGLN SYT11 PDLIM5 YAF2 ELOVL1 IER5 SOAT1 KPNA4 PARVA SYNPO2L TMCC3 GRB10 EID1 CNN2 SPSB1 GHR CFL2 DUSP6 TMEM30A TMEM43 MYH10 ITGB1 SH3GLB1 ZYX	down	**
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	0.0036913	0.0321952	0.4317077	0.2902545	1.418511	385	SLC9A3 PRR15 GPR156 SCIN ENTPD2 SLC5A5 MEX3A SLC13A3 CHST6 GALNT6 KBTBD12 PKP1 SLC25A21 ECE2 SLC26A8 ILDR1 IGFBP6 LYPD6B CD164L2 GRIN2A SP5 DLGAP1 MARVELD3 MOCOS INSRR P2RX2 PCDHGA11 AP1G2 MANSC1 KREMEN2 LTB4R2 LAMC2 CUL9 SPAG16 F2RL1 CBLC CYP24A1 MAP10 THBS4 HHAT ITGB4 P4HTM SYCP2 TTC22 DCDC2 HORMAD1 AP1M2 B3GNT3 ASS1 PROM2 SLC45A1 ABCB9 OXTR HSF4 GRHL2 PRRT3 AFAP1L2 KRT18 OSMR STK32A TNFRSF25 DMGDH TCF20 SPAG6 ARTN SLC44A3 WDR86 SEMA4F IRF6 ST14 FAH KY MAPK13 C9orf50 GRIN3B SPATA32 KRT19 LTBR TMEM30B DHTKD1 NAGS AGBL2 DDIT4L TUBG2 NRXN2 COL26A1 CHMP4C TFCP2L1 WNT10B MYO5C LRRC15 ODF3B SSH3 TMCO4 PARP14 IFITM10 PKDREJ CHRNA3 IL12RB2 CDCP1 MAB21L1 HTRA3 MSH4 SH3D21	up	*
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3	0.0003114	0.0043542	0.4984931	0.2823267	1.417975	632	ATP10B PRR15 CEACAM1 PCSK6 PTPRZ1 B3GALT5 LINC00342 SLC16A14 MUC13 HS3ST1 SLC16A9 FUT6 C1GALT1 OR7E14P GMDS BDH1 PAX9 EPN3 LRIG3 ZMYND8 CP GALNT6 EYA2 TRNP1 PTPRN2 FUT3 WFDC2 TOX3 CLGN PTPRH LCN2 MUC5AC AGFG2 ASIC1 SLC27A2 ILDR1 BCAS1 BAIAP2L1 PAK6 GOLGB1 C4orf19 PRKCA XPNPEP1 PLEKHA7 EFNA5 HPS3 CIB1 TMCC1 MUC20 PDE9A B4GALT4 LRRC31 AOC1 KCNG3 CYP3A5 PLEKHS1 GOLPH3L MANSC1 TTLL4 TMEM41A GOLPH3 OSBPL2 GFPT1 IGF2BP2 BPIFB1 KLHDC7A CPD TPCN1 RGL1 BRPF3 SLC4A11 WDR72 OAZ3 B3GNT3 HEBP2 KDELR2 IFT172 STEAP4 C2orf72 TBC1D8 BACE2 CAPS EHF PTGFRN IDH2 SPRY1 DYRK2 PTPN3 PRRT3 NSF PAK1 LRRC6 CLMN ZNF652 GBP3 FAM114A1 EEPD1 ABHD17C DCBLD1 ADAP1 OAT STEAP1 MIR570 SDCBP2 NARF CNOT11 SLC44A3 SLC2A13 MYO5B RAB6B FER1L4 OCIAD2 CXCL17 RTP4 TSPAN1 DAP SNCAIP TBC1D9B ST14 RGS17 ATP7B CTSV TMTC2 CASP7 LMTK2 S100A9 SPAG1 SRD5A3 GALNT3 GK5 EPB41L4B GALNT7 ENC1 CNDP2 CLDN12 CENPV GOLM1 PLD1 PPP1R3D ENTPD3 ABCC3 CLINT1 ZNF320 BLCAP DPY19L2 ADD3 SCYL3 SNX11 CREB3L2 ETV6 WDR45B STK39 TMEM45B CORO2A TC2N C1QTNF3 CDRT4 KLHL7 SPAG4 CEACAM5 PRPF18 LRP11 FAM3C TMC5 LPIN1 AP001372.2 OSBPL10 TMEM44 SNX7 TRIP4 LRRC8B ARHGAP5 FBN2 SCOC ECHS1 RUNDC1 RDH10 TRAK1 AIFM2 NME7 FAM118B GNA14 HOXB2 SLC12A2 UQCRQ ENTPD7 SYNRG LIF GNE ANKMY2 CGN PGPEP1 ALG1 ANKS6 NSUN7 COPZ2 TAX1BP1 MUC1 WIPI1 PLIN5 PTPN13 ACAD8 KLHL2 ERCC3 PCTP ERLIN1	up	**
VERHAAK_AML_WITH_NPM1_MUTATED_DN	0.0024090	0.0232117	0.4317077	-0.2608727	-1.417723	207	DPYSL2 FCER1A CAV1 CLEC10A MEF2A MSLN CD1C AGTPBP1 HSPG2 ABCB1 ERG PTPRM CACNA2D2 TMEM204 HSPB1 ADIPOR1 DACH1 GATA3 GNG7 SPTBN1 PTGIR FOXO1 GPA33 RUNX1T1 PRKD3 MPL NPR3 GMPR PDE3B HOPX CCND2 TM6SF1 DSE MYH11 DCHS1 HLA-DQA1 RPS6KA2 TMOD1 C2CD2 CD48 HPGDS MN1 PALM PTGER4 GYPC CD7 CST7 CD34 RUNX3 XYLT1 TGFB1I1 GNAI1 GALC PDE4B ARAP2 LDLRAD4 EGFL7 TFPI SPIB ALDH2 CD19 KIT FGFR1 LPAR6 EHD3 BANK1 PMAIP1	down	*
RIGGI_EWING_SARCOMA_PROGENITOR_UP	0.0001425	0.0022035	0.5188481	-0.2479501	-1.413387	351	DAB1 GPR17 KMO CLIC3 TRHDE HVCN1 TBX3 GATA2 WFDC1 FABP4 GIMAP8 RCOR1 LPL LMO2 LDB2 CITED2 AKAP7 SLC39A8 TBXA2R YPEL5 NFATC3 SEMA6D CD36 SH2B3 ASAP1 CARD16 HBEGF MALAT1 KCNK3 BTG2 CYYR1 PRELP FZD4 PAG1 ABHD6 SERPINB9 CES1 PDGFA KDSR ADARB1 CASP1 ZSWIM6 PEG3 PAQR5 TNFSF15 GRK5 NPR3 LAPTM5 ID2 IGFBP2 LBH CCND2 PTGER3 TM6SF1 CYP26B1 HES1 MAPRE2 ARHGDIB ID4 CREM EBF2 RNF141 RGS18 AQP3 SEC14L1 STAT4 GIMAP2 JPH1 JAK1 PTGER4 PODXL PIK3R1 PCGF5 FAM43A KBTBD8 SIGLEC15 MFAP4 MCAM CDK14 PLCG2 FOS CTTNBP2 ICAM2 EPHA3 TGFB1 TCF4 CDC37L1 DUSP5 MCUR1 PDLIM1 PCDH17 MEIS1 FCGRT RIMKLB RGS2 TCF7L1 ICAM1 GPX3 OPN3 PARM1 EPHA4 ACACB ZDHHC21 DAPK1 KIT DUSP7 NR3C2 TOX2 SPATA13 SLFN11 FNBP1 REEP1 KALRN CTSH ZBTB16 BHLHE41 DUSP6 FADS3 ATP11B C5 MAMDC2 ANKS1A	down	**
GOLDRATH_ANTIGEN_RESPONSE	0.0049093	0.0400949	0.4070179	0.2943174	1.412791	306	TRIP13 KIF20A CDC45 MCM10 NEK2 CCNB1 UBE2T PRIM2 BRCA1 TTK RACGAP1 IQGAP3 E2F8 GTSE1 ANLN ASPM PLK1 CDCA8 AURKB CENPA ECT2 CDC6 GAPDH CCNB2 FIGNL1 MCM4 TYMS PRC1 CCNF HBB DTL LILRB4 SPDL1 CISD1 CHAF1A MKI67 BUB1 TOP2A AURKA KIF2C RRM2 CDCA5 GCAT SERPINA3 KIF11 MCM3 LMNB1 CDC25C LIG1 CD24 TOPBP1 CHEK1 MAD2L1 RAD51AP1 PERP GNPDA1 INCENP CKS1B CDKN2C NUSAP1 CBX5 ASF1B CDK1 BIRC5 GMNN POLR3K IGHG1 DNA2 FEN1 SSX2IP EZH2 ETFB	up	*
LEE_RECENT_THYMIC_EMIGRANT	0.0037427	0.0325273	0.4317077	-0.2614347	-1.406881	199	SIDT2 DENND5A P2RY1 KLHL8 TMOD3 CCRL2 CBL HEG1 RBM7 TRA2B RNF144B ZBTB21 GATA3 SLC25A37 CD93 SPRY2 PDE4D MPEG1 GPA33 YBX3 ANKRD10 STK17B ID2 CEP57 N4BP2L1 UBASH3B TAF13 SOCS3 JUN ARL6IP6 ATP11A PTGER4 CCR7 PCGF5 TAGLN2 ZCCHC9 ING3 TIMP2 VAV3 TCF4 NAPSB GNAI1 MCUR1 PDLIM1 GNB4 TOB1 CRY1 HACE1 RNF138 METTL21A CCR9 DAPK1 FNIP2 B3GNT2 THRAP3 GPR171 RPL18A TOX2 NIPSNAP3A	down	*
HORIUCHI_WTAP_TARGETS_UP	0.0027876	0.0255939	0.4317077	-0.2517681	-1.403480	268	CXCL3 ACP5 HMOX1 ABHD5 CXCL16 EDNRB EMCN NR3C1 USP47 PPM1D RFTN1 ZEB2 TXNIP PTPRM ASAH1 ENTPD1 ZNF503 PAQR3 ZBTB8A TFEC CD58 PER3 ARRB1 CASP1 BST1 KLF4 TPP1 SSH1 RIT1 NR1D2 CXCL2 ATF3 RECK IL7R FOXN3 LACC1 PRCP MYLIP FLT1 SAR1A CYB5R1 C2CD2 SNX29 OSTM1 DNASE2 IFRD1 PCGF5 ENTPD4 TMEM167B PDZD2 CXCL5 APH1B PELI1 HIVEP2 TREX1 WHAMMP3 SMCR8 TSC22D1 DUSP5 LRRC32 PCDH17 SOD2 ANKRD12 STX12 RGS2 ZNF267 TAGLN ICAM1 CPQ OPN3 FAM167B TFPI CEBPD ALDH6A1 BRWD1 LIMCH1 FNIP2 RORA CREG1 RNF13 MAN1C1	down	*
MOOTHA_MITOCHONDRIA	0.0031341	0.0282270	0.4317077	0.2871984	1.400808	371	CPS1 BIK AK4 BDH1 TSFM SLC25A21 MRPL46 NPIPB3 NDUFS6 TOMM34 NNT CYP27B1 SHMT2 MRPS35 COX11 CASP2 NDUFB8 SDHA MRPL15 PCCB NDUFS2 LARS2 MPO AMACR MRPL3 OAZ3 EHHADH MRPS11 CAD ETFA FDXR MRPS30 TST IDH2 SLC25A10 UQCR11 MB SSBP1 PLA2G2A GOT2 OAT ACP6 MCAT MRPS2 PRPF6 SLC25A13 MRPL17 PDK1 MRPS12 ETFB MAST1 CPT1B UQCRFS1 NFS1 SPG7 MRPS34 LONP1 DHODH MRPL11 TPO COX7C PPOX MRPL4 DAP3 SLC1A3 COX10 NT5M YARS2 TIMM13 SIRT4 BCL2L1 MRPL24 MRPS33 CKMT2 MRPL28 HAX1 AMT FARSA PYCR1 POLR3B NME4 ABCF2 UQCRC1 COX5B ECHS1 MRPL9 NDUFA8 NDUFS8 ERBB2 CPOX TBCB VDAC3 POLR1B MTHFD1 TP53 SBNO2 TIMM44 MRPS27 BCAT2 MRPL20 ADCK2 MRPL48 NDUFB7 COX6B1 DNM1L TK2 COX17 ACAD8 CYP11A1 CYB5B TFB1M SARDH BCKDK POLRMT MRPS16 UCP3 DGUOK MRPL12 CRAT BAK1 MRPL2 TOMM40 TIMM10 TYMP MPST SHB IMP3 CS PPA1 NDUFB2 TXN2 PC COX15 TIMM9 LYPLA2 MTHFD2 COX6A1 METTL17 FIBP COX6C ABCB8 SDHC MRPS7 ACADS MRPL35 MRPL13 GATM MRPL33 CROT NDUFA10 BCKDHA SUCLG1 DDX28 IDH3A TIMM23 NDUFS4 TNFSF10 CYP2E1 PYGB CNNM4 PMPCB NPIPA1	up	*
REACTOME_HEMOSTASIS	0.0001170	0.0018785	0.5384341	-0.2329305	-1.397696	532	ANGPT4 WEE1 CLEC1B TEK OLR1 PECAM1 GATA2 SPN CLEC3B PRKG2 F2RL3 P2RY1 TUBB1 THBD RCOR1 TRPC3 FYN MMRN1 CD44 PDE1B CTSW CAV1 ESAM IGKV1-33 TBXA2R PRKAR1A CDC42 CD9 GAS6 FGR RHOA PDE2A CD36 ATP2B1 SH2B3 IGKV2-28 SLC7A7 RAPGEF4 RAP1A GNGT2 ITGA5 ANXA5 SLC7A11 ABHD6 GATA3 JAM3 GNG7 SIRPA CRK SRGN PDGFA TUBB6 CD58 RHOB KIF1C CFD ARRB1 PTGIR DGKE KCNMA1 PLAUR SLC7A8 THBS1 MAFG MPL KIF26A FAM49B ABCC4 ITPK1 DOCK9 ITGAX KCNMB1 SELL SELP JAM2 CAPZA2 FCER1G PLEK PPP2R5C PPP2R5A GNAQ PIK3R5 GNAI2 MAFF MRVI1 VWF TGFB2 PROCR PRCP IGLV2-11 SLC8A1 PPP2CA PHACTR2 CABLES1 CYB5R1 SERPINB8 CD48 PDE5A RAC2 TREM1 RHOG PIK3R1 GYPC PRKCE GRB2 SERPINB6 CAP1 PRKACA DOCK8 YWHAZ TNFRSF10B TAGLN2 IGKV3-20 PLCG2 SLC3A2 CALM1 EHD2 PRKCG DGKG CD74 DAGLA PPP2CB STXBP3 TGFB1 EHD1 VAV3 TMX3 VPREB3 CDC37L1 GNAI1 GNG5 SLC8A3 GNB4 APLP2 DOK2 IGHV3-23 ORM2 GATA6 GNA13 ACTN2	down	**
TIEN_INTESTINE_PROBIOTICS_24HR_UP	0.0027571	0.0254975	0.4317077	0.2807304	1.394466	504	PPM1H TRIP13 FOXM1 KIF20A HJURP GALNT6 BUB1B NUP107 CCNB1 CENPF DROSHA PAIP1 CPSF6 TTF2 NDC80 TBRG4 MRPL46 GINS1 RACGAP1 GTSE1 KIF14 DNMT3B PLK1 CENPA PTTG1 ESPL1 MCM4 MCM2 TYMS CDC25A UMPS PRC1 GLDC ZWINT LSM5 NME1 HMMR NUDT1 KIF23 BUB1 MSX2 AURKA TMEM177 LARS2 MCM7 TPCN1 RRM2 SMYD2 PDCD5 KIF11 MCM3 EMG1 BRD9 PLXNA1 MORC2 TOPBP1 DNAJC9 THYN1 MAD2L1 TRMT61B RAD51AP1 DCTPP1 PHB CNPY2 SKP2 CKLF GEMIN4 PON2 NUSAP1 NSF POLE2 EXOSC2 GMNN OAT POLR3K UNG MRPS2 SLC25A13 FEN1 SPAG5 SNRPE LAPTM4B SNRNP25 DNMT1 ST14 DPP3 TUBG1 DLGAP5 SPG7 COA3 UBAC1 ADAT1 ALDH7A1 LMNB2 TUBB2A HMGN3 TK1 ADAR GINS2 ANP32E AGPAT5 ENOSF1 NDUFA13 PSMD2 NUP85 SUPT16H TIMM13 BRD8 IARS2 ACLY RPA1 SRRT MCM6 MED24 MCM5 SNRPD1 LSM7 CLUH SRSF1 GINS3 LSM4 NEDD8 KLHL7 AGMAT TM7SF3 CCNA2 ADM GTF3C2 DENR PDF SHCBP1 ATOX1 TTC1 ECHS1 MRPL9 NDUFA8 UBAP2L AURKAIP1 PGAM1 VDAC3 TNS3 CIAPIN1 FAIM DDX52 PCBD1 SLC36A1 PNN MRPL20 NUP93 COX17 ARHGAP8 ERCC3 ERLIN1 NCAPH CYB5B TPM1 APOBEC3B RCN2 LUC7L3 MIOS C12orf43 ADSL LPCAT1 FBXO5 LGR4 FASTKD3 OPA1 KRIT1 TMPO GLRX5 MPZL1 MSH6 SAFB2 ABCD3 MTRR DGCR2 RBM8A NDUFB2 CCDC86 NAE1 HNRNPAB TIPIN	up	*
MARTINEZ_RB1_AND_TP53_TARGETS_UP	0.0001813	0.0027133	0.5188481	-0.2320819	-1.391302	509	SLC6A4 GPD1 WEE1 EPAS1 EREG HSPB7 PECAM1 LRRC8C FABP4 MNDA CAT USHBP1 EMP2 CYP4B1 LIPA RAMP2 CDH5 ARRDC4 LPL HSD17B11 CD44 BAG4 QKI SLC25A30 ARL8B MSRA MEF2A ALAS1 NR3C1 TGFBR3 NCF2 FUCA1 TGFBR2 TRIB1 PILRA SPCS3 GINM1 TXNIP CD36 STARD4 CLCF1 BMP1 BZW1 PRELP RANBP9 NLK LITAF HDC ZNF410 HIPK3 CAV2 LCP1 SERPINB9 STOM PPP3CA NR4A1 SIRPA RGCC IL18R1 SPTBN1 SRGN TCAP UBE2D3 TFRC PDGFA HIF3A MSR1 CFD SORBS1 LIMS1 ST3GAL2 PRKD3 DRAM1 THBS1 CLDN5 ITIH5 CDKN1A RBMS1 ATF3 CTBS CCND2 TM6SF1 DUSP1 ALOX5AP WDR48 PINK1 HLA-DQA1 ADD1 MAPRE2 TGFB2 PDK4 ZNF330 SPIN1 RBP7 HCAR3 SAR1A NSMAF ESD RAB31 SLC14A1 TYROBP RABGAP1 JAK1 PRKCE MORC3 TPP2 IP6K1 CELF2 ACSL1 MOB1A FOS UBB PNPLA2 KLB CD74 CPA3 SORT1 ZNF521 CHPT1 PEA15 ITGA9 SERPINB1 HBP1 GNA13 SERINC3 MR1 TSPO PCCA SOD3 ARPP19 RXRA CCL20 AMD1 PDLIM5 DCTN4 RTN4 PIP4K2A MFAP5 CALCOCO2 NSUN4 ACTB HAVCR2 PSME4 PLGRKT TMEM109	down	**
PEDRIOLI_MIR31_TARGETS_DN	0.0005435	0.0068664	0.4772708	-0.2435424	-1.390904	340	SLC6A4 ANGPT4 HSPA12B ACE EDNRB USP12 SECISBP2L CD55 LYVE1 RAMP2 MMRN1 LDB2 DDX6 CDH13 MYD88 NCF2 TGFBR2 IL23A ARHGAP29 PKHD1L1 CNST SBDS TACC1 LATS2 CHRNE ABCG2 EMILIN2 LITAF KLF6 RNASE1 HLX SLC7A11 ZMYM6 MED26 CD93 LAMTOR3 FOXC2 SLC5A2 PPM1K AFAP1L1 ADAMTS9 CLDN5 CXCL2 IRAK2 N4BP2L1 GPR157 RUFY3 ANXA3 BACE1 VWF ZDHHC20 CLN8 PRCP PDK4 KANK1 RBPJ ARL6IP5 TMOD1 CREM VAT1 DESI2 ATXN1L SUGT1P3 DAPK2 ACKR3 KLHL18 IDNK CAP1 PDZD2 RASSF2 SPRY4 CWF19L2 CD164 ZFAND6 SMPDL3B GSAP SBF2 SOD2 DOK2 SPOCK2 CCL20 ICAM1 LDLRAD4 SLC31A1 OPN3 CHMP3 DCTN4 CDKN1C VPS4B EXD3	down	**
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN	0.0001916	0.0028519	0.5188481	0.2724095	1.383131	894	TRIP13 FAM201A GALNT14 RUVBL1 AK4 GMDS BDH1 DEPTOR RPGRIP1L COIL TRNP1 DNAJC12 FLVCR1 MPP6 PDCD2L SLC2A1 CHST4 PLEKHH1 CCDC113 SORD ECE2 HILPDA TTC26 EBF3 ALDH18A1 SFXN1 KNOP1 UMPS EIF3B ACY1 MCM8 XPO5 COQ3 COX11 PVT1 WDR90 NUB1 NME1 RANBP1 CLPTM1L RUVBL2 BZW2 ZNF74 NOP9 DCBLD2 QTRT1 PUS7 NUP155 WDR3 MYO10 TMEM177 ATR SLC29A2 POLD2 TPR MPO CENPW DPCD ABCC5 TTLL12 RBM28 PDCD5 GCAT AKAP1 DUSP23 ANKMY1 SOX4 L3HYPDH ZNF530 FAM162A PSMG4 ZNF618 C7orf50 MAD2L1 FBL SLC25A39 DCTPP1 DNAAF3 TIMM50 HES6 AKT2 OXER1 ETFA RAD18 MRPS30 PHB ERCC2 ALG3 MGLL SLC25A10 HSPBP1 SPRY1 CCDC138 SKP2 DYRK2 PES1 GEMIN4 THOP1 TMED3 MRPL36 ISOC2 ANAPC5 HDGF UCK2 BCAS4 CCT3 GOT2 NPM3 DHX37 TRAP1 MCAT DHX33 GNPNAT1 FSBP POLR1C ACTR3B TNPO2 MRPS12 RNF207 TMEM120B ATAD3A NLN NOP2 LAPTM4B FGFR1OP STK11 PA2G4 ZNF692 RANGAP1 FAM86C1 NRGN HSPA4L MPI POLR2H SNRNP25 MYO19 TELO2 C19orf44 PDCD11 SCLY NDUFA11 PSMA5 TRMU C12orf45 MRPS34 DHODH TUBB2A PTGES2 SLC37A4 HMGN3 MORN2 COPS7B DPH2 ENAH MYBBP1A MSI2 ZNF816 GEMIN5 FZR1 MRPL4 PKP4 KIF20B NOC2L DNAJC11 CLTB RMND5B GEMIN6 CENPV PFAS TIMM13 GOLM1 L3MBTL2 KLHL23 DCUN1D5 CENPM RRP9 GPATCH4 POP7 FAM136A MRPS23 NOL6 SRRT MRPL24 PEX5 MRPL41 MED24 PRMT1 UTP20 TMEM147 NOC4L WDR35 HEATR1 LSM7 RABEPK CLUH LTV1 URB1 EXOSC5 CREB3L2 RNASET2 RCC1 TXNL4A AP4B1 ZDHHC11 MARCKS NEFH TSR1 PRMT5 STRBP NUP62 FARSA MRPL14 AGMAT ALMS1 RPS26 TM7SF3 SLC2A5 SCO2 DDX54 VDAC1 MRPS25 DOHH NME4 TUBGCP4 PDAP1 ABCF2 WDR4 WDR77 PRPF31 MLLT6 ATOX1 BMP8B N6AMT1 GADD45GIP1 CHMP1A MROH1 ZMYND19 ERGIC1 RDH10 MRPL21 LLPH SNRNP70 FAM118B LRG1 RHOT2 UBAP2L AURKAIP1 CIAPIN1 CLEC11A POLR1B SPR TCF3 POLR1A EARS2 ADAM15 ALG1 ANKS6 TBL3 PIGL ARMC10 SFXN4 DTD2 SLC35G1 PWP1 PPP2R5D DHRS9 RAD1 NDUFB7 RRS1 MRPS26 TMEM201 PPP1R14B ACTR5 ATP6V1E2 ACSL5 ALKBH2 TTC5 DAZAP1 STK33 FGFBP3 DHX57 MRTO4 SLC40A1 LUC7L3 RNF126 PM20D2 SRM C4orf48 PPARGC1B TRAFD1 MRPL12 DFFB	up	**
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	0.0003854	0.0052532	0.4984931	-0.2351478	-1.376631	424	DLC1 DENND5A RAPGEF2 RCOR1 BDNF FYN KIAA1109 QKI SRSF7 DYRK1A NR3C1 RFTN1 HEG1 NUMB ARHGAP29 ATP2B1 UBL3 PBX3 PICALM REV3L KLF10 KLF6 EIF4E PPP2R2A FOXJ3 RB1 HNRNPDL ITSN2 TCF7L2 TIPARP ZMIZ1 ADARB1 PTPN12 ROCK2 TLE4 ACSL3 SOCS5 KLF7 MYO1B GAPVD1 SEC24B PDE8A RBMS1 CDS2 EPS15 CCSER2 WASF3 DUSP1 MBD2 PPP2R5C GNAQ OXSR1 IL7R PAFAH1B1 KPNA3 TP53BP2 AFF1 CRIM1 MARK3 NCOA1 TGFB2 STK24 TDRD7 FOXN3 RAB6A RBM39 RBPJ PPP2CA BCAR3 NEK7 PIKFYVE SEC14L1 SRSF3 C2CD2 JUN RABGAP1 FERMT2 DHX15 IPO7 ZNF804A FRYL CREB1 HOMER1 UVRAG TUBGCP3 WDR7 CDK17 HIVEP2 FOXO3 PKD2 SPOP NUP153 PHF3 BAZ2B ZFYVE9 PIK3C3 NFYC ORC2 CRY1 ADAM10 PHLPP2 MBNL1 ATAD2B HELZ FGF2 CEP170 NBN TIAM1 PIP4K2A TRAPPC8 EPHA4 TAB2 SIK3 ARIH1 NUP98 CREBBP DAPK1 LIMCH1 GTF2F2 PTEN TLK2 CAMSAP2 NRG1 TLK1 PUM1 RNF13 EVI5 ABI1 STARD13 UBR2 SERPINE1 CLIP1 ATP11B ATF2 LHFPL2 CLOCK	down	**
LEE_BMP2_TARGETS_DN	0.0002784	0.0039508	0.4984931	0.2713464	1.372029	801	SHISA3 TRIP13 FGA MEX3A HELLS RUVBL1 AK4 CDC45 MCM10 BHMT NGEF NUP107 FLVCR1 CPSF6 PSPH TTF2 TBRG4 BRCA1 PHGDH CDCA7 THEM5 TTK GINS1 E2F8 TRAIP GMPS BAMBI IGSF11 CDC6 E2F3 FIGNL1 UHRF1 KNOP1 MCM4 MCM2 CDC25A UMPS COL22A1 DTL CCT6A XPO5 MIS18A SRPK1 SHMT2 XPOT ZWINT CDT1 AOC1 SPDL1 SIMC1 KAZALD1 NME1 HAUS5 RANBP1 TTLL4 RUVBL2 MELK DNPH1 EXO1 CISD1 NLE1 BUB1 FANCA EEF1E1 AURKA NUP155 WDR3 MCM7 CENPW CLSPN RRM2 MMS22L WDHD1 NSUN2 MCM3 CHAF1B PFN2 TARS2 SMYD5 TOPBP1 CHEK1 ASS1 ORC6 ACTL6A MAD2L1 CSRNP2 RAD51AP1 DCTPP1 PRMT6 CAD BLM NIPAL1 ALG3 SKP2 PARP1 DDX56 GEMIN4 THOP1 CKS1B CXCL14 DDX51 ASF1B POLE2 MCTP2 UCK2 CCT3 C1orf112 ATIC DCBLD1 GMNN GTF2E1 POLR3K UNG KCTD13 STEAP1 PRRX2 L2HGDH DNA2 MRPS2 SLC25A13 DHX33 PSAT1 ANKRD26 LARP1 FEN1 EZH2 NUP205 SF3B3 ATAD3A NLN NOP2 PA2G4 KPNB1 MPI DNMT1 ILF2 CCNE1 CEP192 PDCD11 ADAM12 FOXRED1 YDJC DNAJA3 LMNB2 MNS1 DHODH EPHB2 DPH2 ENAH C1orf131 MYBBP1A CENPQ MFSD2A HDAC1 MLEC GEMIN5 ANP32E AGPAT5 DLK2 NOC2L PRMT7 ASNS NUP85 ATAD5 COX10 ENC1 ELAC2 CCT7 YARS2 GEMIN6 PTN PFAS PPP1R8 LRRC59 FAM136A RPA1 CDR2 MCM6 RPL7L1 PRMT1 UTP20 MCM5 NOC4L HEATR1 ACOT11 HAUS6 CLUH LTV1 SRSF1 URB1 DNAJC21 DUS4L RCC1 ATAD2 TSR1 TCERG1 GTPBP10 SUV39H2 ME1 RTEL1 PDF USP39 WDR4 PCSK5 ABHD10 WDR77 HK2 LPGAT1 RAD51 FARSB ZWILCH SCOC ZMYND19 TARBP1 PAXIP1 ACP1 FAM118B WDR76 PGAM1 RBM19 ZNF131 CIAPIN1 FAIM POLR1B POLR1A PFDN4 MTHFD1 TRUB1 APEX1 TBL3 PNN NCAPD3 RASGRP1 MRPL20 PWP1 NOMO1 E2F7 RRS1 NAT10 NUP93 CYP11A1 BRIX1 RANGRF C9orf40 PCGF6 CLNS1A CD38	up	**
HOSHIDA_LIVER_CANCER_SUBCLASS_S1	0.0064214	0.0490356	0.4070179	-0.2506210	-1.368586	210	ACP5 DPYSL2 PPP4R1 BCL2A1 CD8A RHOA ANXA1 ASAH1 IFI30 ANXA5 LITAF RNASE1 LCP1 MPHOSPH6 GRN AKT3 SRGN CD37 ATP6V1B2 PLAUR ID3 DAB2 STX3 CCL3 LAPTM5 RIT1 PTPRC PAPSS1 CCND2 M6PR CD53 ALOX5AP IL7R GNAI2 ARHGDIB PROCR NSMAF CTSS IL2RB CD48 RAB31 LTBP2 ATP6V0B CCR7 GLIPR1 GYPC RALB CELF2 CD151 PKD2 CD74 RIN2 TIMP2 TCF4 PEA15 DUSP5 COL15A1 TAGLN SMAD2 GEM ARPC2 CXCR4 CTSC LTBP3 IQGAP1 DUT RSU1 PPP1CB KLC1 CYBA C1QB	down	*
ONKEN_UVEAL_MELANOMA_DN	0.0005395	0.0068477	0.4772708	-0.2306830	-1.361232	458	RAB11FIP1 SEMA6A ACP5 DLC1 EDNRB SECISBP2L LTA4H PTP4A2 DPYSL2 SIK1 FYN CD44 EMCN ST3GAL6 CAV1 PCOLCE2 ARL8B PRKAR1A NEDD9 LAMP1 LYRM4 RHOA TXNIP TBX2 UBL3 SLC3A1 ASAH1 ENTPD1 MASP1 CAV2 BFAR ABHD6 SERPINB9 JAM3 SIRPA ADRB2 HNRNPDL SPRY2 KANK2 PDE4D TIPARP EIF1B DUSP3 SORBS1 PXDC1 ZNF423 KLF11 DAB2 TJP1 TPP1 EPM2A PMM1 ID2 TLR4 CEP57 M6PR GCA MATN2 DSTN RSL24D1 DEGS1 RABGGTB CMTM6 GLB1 BTG1 PRCP SPIN1 VAMP3 ID4 RYBP PGD SNAP23 APPL1 LAMB2 MTMR14 BAG5 PIK3R1 CD83 MBNL2 GYPC COBLL1 SERPINB6 ATP13A3 NOL7 FSTL3 TSPYL1 CGGBP1 SNRK IP6K1 MCAM LMCD1 PTP4A1 FOXO3 ATG3 ING3 GNAI1 ATP6V1A TSPAN14 GALC NFYC PLSCR4 CSDE1 GABARAPL1 CSNK2A2 KAT2B PDE4B MBNL1 HSPA2 SLC35D2 WDR1 ALDH6A1 IPO5 GPD1L KPNA4 GLUL TIMP3 PTEN FDFT1 MTUS1 GTPBP8 DAZAP2 NRP2 RPL18A CREG1 LPAR6 EIF4A2 RNF13 BMI1 DNAJA2 CBX7 USP4 CRTAP SLC25A38 ATP11B CRBN EIF3L PRKCH TGOLN2 GPR153	down	**
HADDAD_B_LYMPHOCYTE_PROGENITOR	0.0061838	0.0475497	0.4070179	-0.2479345	-1.358478	226	SEMA6A SECISBP2L PTPRE PLEKHF2 CAV1 CITED2 ELF2 MEF2A CD9 CD22 DNAJB14 EDEM1 PLXNA2 ABCG2 BTG2 MS4A1 GNG7 RB1 ZFYVE16 PPP3CC RHOB TLE4 FOXO1 ZNF423 ID3 ANKRD10 SOCS2 LAPTM5 UXS1 LBH ELK3 WFS1 IL7R CRIM1 SNN BTG1 KIF13A JUN MAP4K4 AK1 SNX2 ENTPD4 MSANTD2 DLEU2 AGFG1 CALM1 PKD2 MME GSAP TCF4 DCK TGIF1 PDS5B VPREB3 TSPAN14 IRS2 SOD2 TOB1 KAT2B ATAD2B ARAP2 LDLRAD4	down	*
MARSON_BOUND_BY_FOXP3_STIMULATED	0.0000152	0.0003177	0.5933255	-0.2191558	-1.357138	795	SLC6A4 PECAM1 MNDA LPXN GPR65 DPYSL2 INSIG1 FYN EGR2 TMOD3 PPP4R1 BACH1 RTN3 CITED2 AQP9 SFR1 DYRK1A KBTBD3 NEDD9 TSHZ1 PSMD5 NFATC3 TLCD2 RCHY1 FGR RHOA DNAJB14 AVPI1 EDEM1 ARHGAP10 SH2B3 UBL3 RAP1A EIF5 TNIP3 SERINC1 ACOT2 PICALM CNTD1 KLF6 M1AP IFNK EIF4E FOXJ3 TOR1AIP1 HNRNPDL PPP1R13B SRGN EPM2AIP1 UBE2D3 TXN ARL11 MCL1 TIPARP EPB41L2 CCNI ROCK2 CSRNP1 ITPRIP PPT1 SCP2 SDCBP MEFV BNIP2 ITM2B COQ10B REST LEPROTL1 UHRF1BP1L ZFAND5 ZADH2 TMED5 LY96 SPAG9 CTSD ITIH5 ATL3 PTPRC KCTD20 PER1 MFSD11 SMAD7 EVI2A WFS1 PPP2R5A PEAK1 KPNA3 PLCD1 ADD1 CNOT6L MAPRE2 ARHGDIB ZNF426 SLC25A33 TCTE3 ZNF330 RBPJ ARL6IP5 ETF1 METAP1 WASF2 CDC40 PHTF2 SGK1 PSEN1 NEK7 RAB8B PIKFYVE HCST SRSF3 ETV3 ARL5B ARL6IP6 ETS1 OSBPL9 MAP4K4 JUNB RHOG PTGER4 FYTTD1 STX7 SKIL EEA1 GLIPR1 IRF8 LYRM1 HSPA13 GMFG HERC1 GYPC FAM43A CREB1 COBLL1 TMEM167B REL CAP1 TNFRSF9 DENND4A EPC2 LETM2 TOM1L2 NDUFV2 BLOC1S6 ACOT1 SLC3A2 SLC25A24 UBB CDK17 YTHDF3 RBKS ING3 ZFAND6 CCR4 NUP153 AKIRIN2 GSAP ZBTB1 JMJD6 TGIF1 TESK2 KCTD10 ABHD13 VAMP4 FEM1B ZBTB11-AS1 ZC3H12D PDCD1 PIM1 ATXN1 C8orf37 KCNA3 APLP2 CCR1 NPTN KANSL2 RGS2 GPR18 KAT2B ADAM10 TTC24 KTI12 MBNL1 FAM98B TCTEX1D4 RBL2 SESN1 MIER1 FKBP1A SEMA4A MTO1 ORMDL1 TAB2 GIMAP5 ZBTB25 ARIH1 DIXDC1 UBE2D1 ISCU PLGRKT NPAT LYSMD3 CUL3 CEPT1 ADORA2A CD3G GPR171 PAIP2 SAMSN1 SLC22A3 CCND3 NABP1 RAB2A USP48 DNAJA2 PPP1CB IRF2 CBX7 AFTPH UBE2V1 ATP6V0A1 MRPS28 USP4 TMEM50A CDKN1B UBXN8 DUSP6 TMEM30A CLIP1 FIP1L1 CENPC CX3CR1 LNPEP ITGAL DCUN1D3 TGOLN2 PDCD2 NCF1 DRAM2 HP1BP3 NDFIP1 DNAJB4 UBE2W DNAJC8 DAPP1 FBXW12 UBE2N BCL10 SGPP1 GABPB1 SLC25A40 STX16 PCMT1 FCGR3A ARHGEF12 TES CD3E ADH1B PNRC2 MAP3K1 SLC23A2 WDR26 TRAT1	down	***
HAN_SATB1_TARGETS_UP	0.0006741	0.0081078	0.4772708	-0.2350352	-1.348359	371	KRT81 RAB11FIP1 EPAS1 SLPI IL1B PTPRE LIPA ENG BDNF FYN STXBP6 SAMHD1 ST3GAL6 CITED2 QKI CYB5R3 HMGCR ARL8B SLC15A3 NEDD9 RGPD5 EPB41L3 SLC25A17 ECHDC1 FZD4 SLC7A11 IL18R1 TNS1 SPTBN1 SRGN EPM2AIP1 PDE4D TCF7L2 APOC1 RHOB ADARB1 EVI2B CASP1 ZCCHC24 TNFSF15 BCHE GRK5 KLF7 ATG7 PDE8A PMM1 CDS2 M6PR WASF3 DUSP1 INHBA MATN2 IL7R CYP26B1 MAFF TGFB2 RPS6KA2 MCMBP PDHX FLT1 IL6 RAB8B LAMB2 SERPINB8 MITF HRH1 CTSZ BMP3 OSTM1 SHOC2 CSTA ZNF804A ATP13A3 DENND4A NDUFV2 MCAM CD34 CD164 MBP RBKS MSMO1	down	**
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	0.0001372	0.0021404	0.5188481	-0.2200197	-1.346704	705	SIDT2 SC5D CD52 FGD5 TMEM126A ZC3H12C CPEB2 WNT4 PTP4A2 RDX SMIM12 SEC22C PLEKHA1 INPP5A PRPF38A ARL8B CDC42 MKNK1 ANAPC15 CBL FRAT1 SYNC FGR CASP9 RHOA AVPI1 RBM7 PTS RRAGC MTF1 PICALM LUZP1 CAMTA1 GPBP1L1 ZBTB8A SLAIN2 FOXJ3 JAM3 MOB3C ZMYM6 TMEM123 EPM2AIP1 MTHFR ZYG11B ZMIZ1 EIF1B EFCAB14 AGO4 PER3 AMOTL1 ARRB1 PPT1 AGO3 CCDC82 SCP2 PSTK BIRC2 SORBS1 PTAFR FAM76A CLIC4 MYRIP SNIP1 ATG7 LAPTM5 LRRC40 CEP57 SS18L2 EPS15 CCSER2 WDR48 ZMPSTE24 LYAR PINK1 CUL5 OXSR1 PEF1 NRBF2 FAM76B AKIRIN1 IKZF5 CMTM6 CPLX1 PI4K2A RAB6A TBC1D5 RBPJ VAMP3 CHDH MED28 PODN PDCD6IP JUN MTMR14 LIMD1 GLUD1 OSBPL9 ATP6V0B BTD CNTN4 SHOC2 VPS26A JAK1 TBC1D12 DHX15 SDHD FRYL RPS6KA1 MSANTD2 CAP1 UVRAG SMIM20 MEAF6 CWF19L2 AZI2 MFSD10 RUNX3 ATPAF1 CHORDC1 PBRM1 SRSF4 ZRANB1 MTMR2 YTHDF2 KHDRBS1 TBRG1 DYNC1LI1 RELL1 HNRNPH3 APLP2 STK40 STX12 CLASP2 MACF1 CLCN6 TMA7 HAUS3 RPP30 MIER1 RLF ELOVL1 IQSEC1 RAB5A SIK3 TTLL7 NSUN4 HSPA8 TBC1D1 RBMS3 HPDL TBCEL NPAT FDX1 ANKRD49 PTEN THRAP3 KIF1B THEMIS2 C1orf52 SFPQ PUM1 FEZ1 GRPEL1 USP48 HPCAL4 MAN1C1 ACAT1 ZBTB44 MED17 PUS3 GPN2 VPS13D SPSB1 CDON USP4 PEX14 C1QB ARHGEF17 TMEM50A SH3BGRL3 FADS3 TMEM43 ZBTB8OS CAPZB CRBN CMPK1 GPR153 SH3GLB1 ECD HP1BP3 NAALAD2 PIGK SRSF11 MUL1 IFIT5 FAM160B1 NOL9 DNAJC8 LDB3 RGS12 C11orf54 EXOC6 ZNF362 BCL10 ACTR1A DDX21 RNF214 ARHGEF12 PNRC2 RPA2 KCNAB2 SH3BP2 SETD2 TAF1D BBIP1 FCHSD2 NKTR RAB11FIP2 CYTL1 MKRN2 SIRT1	down	**
PUJANA_BRCA1_PCC_NETWORK	0.0000308	0.0005911	0.5573322	0.2616180	1.344265	1376	SIM2 RIBC2 TRIP13 HNF1A B3GALT5 DDX11 FOXM1 MDM1 RUVBL1 CDC45 FANCI ZNF273 TROAP CHEK2 BUB1B NEK2 CCNB1 CENPF IGF2BP3 TIMELESS NPAS1 COA1 GGCT TTF2 NDC80 TSFM TTC39A BRCA1 BET1 ECE2 TTK GINS1 EFNA3 CDK4 GTSE1 KIF14 GMPS POLE STIL EIF2B5 NDUFS6 TOMM34 PLK1 AURKB CENPA PTTG1 ESPL1 RGS6 CDC6 B4GALNT1 TPX2 E2F3 GAPDH TFDP2 NNT CCNB2 NBR2 RBBP8 MCM4 MCM2 TYMS XPNPEP1 CDC25A MYBL2 XRCC2 ORC1 CCNF EIF3B CCT6A LIG3 SRPK1 SHMT2 XPOT NCAPD2 ZWINT CDT1 COX11 AP1G2 PVT1 CCT2 ASTN2 LSM5 NME1 LDHB IKBKE TOP3B RANBP1 RUVBL2 CASP2 MELK HMMR EXO1 NUDT1 SMARCC1 KIF23 CHAF1A LAMC2 MKI67 CUL9 HLTF PCCB KNTC1 PAFAH1B3 BUB1 EEF1E1 TOP2A IDO1 CCT5 AURKA SPTB NUP155 CBX3 PMS2P4 POLA2 ATR POLD2 SFI1 LARS2 TPR KIF2C MCM7 CD2AP COASY MPHOSPH9 RRM2 PRKDC WDHD1 RAD54L ERAL1 MRPL3 KIF11 MCM3 CHAF1B LMNB1 CDC25C MCCC2 AIMP2 B3GNTL1 RNFT2 LIG1 POLR3C TOPBP1 CHEK1 DNAJC9 ACTL6A MAD2L1 AHCY FBL RAD51AP1 MDM2 PKMYT1 CAD ETFA BLM CNOT3 GLE1 MNAT1 MYO1A PARP1 PES1 GEMIN4 THOP1 CKS1B EFCAB11 CDKN2C MEA1 PPIL2 TMEM106C CBX5 ANAPC5 IQCB1 CDK1 PABPN1 HDGF SSBP1 POLE2 SNX4 DIDO1 UCK2 CCT3 ATIC GTF2E1 RBCK1 NPM3 E2F1 UNG TCF20 TRAP1 SNAPC1 DNA2 SEC61G KIF2A ANKRD26 PDK1 FEN1 EZH2 NUP205 POLR1C SPAG5 KXD1 TAF6 LRRC42 PLCG1 OARD1 TTI1 SNRPE NOP2 PSMC4 RECQL4 ITGA2B FGFR1OP PA2G4 RNASEH2A DNAJC7 KPNB1 POLR2H TBX1 DNMT1 VBP1 PELP1 UBFD1 TELO2 ILF2 CCNE1 NPHP1 TRIM24 CDC23 GNPAT DLGAP5 PSMA5 ADNP MTOR GSS SNRPA LMNB2 MBD4 GALNS PSME2 OSBPL3 HIRA HMGN3 ZNF37A SSRP1 DPH2 TK1 DTYMK CASP7 HDAC1 ANP32E IFNAR2 ITFG2 TCEA1 KIF20B DAP3 IGHM NOC2L ASNS TM9SF4 SAP30 CDK13 POLB ELAC2 CCT7 CDC7 TNK1 P4HA1 EP400 PFAS CKAP5 CPSF4 KCNB1 CDC20 STOML2 IARS2 PPP1R8 HMGA1 RRP9 CLASRP ACLY RPA1 PPP6R1 POLR2J ZNF202 SRRT CLINT1 PEX5 MCM6 COMP KIF21B TBCA MED24 PRMT1 UTP20 MCM5 SNRPD1 LSM7 TFAP4 EIF3D SRSF1 AATF KATNB1 DOLPP1 RCC1 CCNG1 SLC1A5 LSM4 PSMB4 TXNL4A EIF3K U2AF2 TSR1 TCERG1 ALG8 NUP62 FARSA PYCR1 PMS2P1 PMS1 MSH2 CCNA2 SMARCA4 RBM42 PRIM1 ZNF195 GTF3C2 VDAC1 SNRPD2 RFC5 CSNK1G2 PDAP1 ABCF2 ACKR2 WDR77 PRPF31 HK2 BMS1 RAD51 ST20 ARHGAP11A EYA4 SRP9 TARBP1 PAXIP1 SNRNP200 UBAP2L ZNF131 CIAPIN1 SMC2 PARG GOSR1 XPC CENPE ABO TCF3 PFDN4 DDX52 POP4 SMPD4 TP53 NMT1 PAICS TIMM44 CHERP APEX1 MRPS27 SNRPC PPIA TBL3 UBE2C PNN TAF4 GPN1 NELFA UBTF PWP1 RIMS1 GP1BA ENO1 NUP210 BFSP2 RAD1 SMARCB1 DDB2 RRS1 PLIN3 NUP93 ZNF337 COX17 SART3 TRAPPC6A IFI16 TIPRL ERCC3 NCAPH GEMIN2 CYB5B PARP2 LYPLA1 GRIP2 CLNS1A CD38	up	***
MULLIGHAN_MLL_SIGNATURE_2_UP	0.0008584	0.0100072	0.4772708	-0.2332382	-1.338050	371	SIRPB1 PECAM1 OSBPL1A FBP1 SNX10 CAT ADCY9 COQ2 IL1RN LAMP1 PILRA DPEP2 SPG21 BEST1 PBX3 LCP1 DACH1 LAIR1 TOR1AIP1 SIRPA ADRB2 GRN CES1 SRGN HNRNPU SPI1 ADARB1 EVI2B PPT1 CASP1 PTAFR PLAUR FUT7 GAA MVB12B ARNTL CEBPA ATP6V1D TPP1 LAPTM5 PMM1 ITGAX CTBS ID2 CD302 RECK M6PR PLEKHB2 CD300C ACTR2 TDRD7 HEXB HCK RAB6A ARL6IP5 PSEN1 RAC2 NXPE3 CSTA TMEM251 SDHD GRB2 MALT1 RPS6KA1 TNFRSF10B RASSF2 CLN3 TNFSF13 RBKS ATG3 ALDH3B1 TREX1 NKG7 TRAPPC10 WHAMMP3 FXYD6 TFEB ATXN1 MEIS1 CCR1 THAP11 KYNU CLASP2 MR1 MBNL1 RXRA PITPNA SELPLG ARPC2 SLC31A1 CDC42EP3 CXCR4 NLRP3 SCPEP1 S100A4 COMMD8 DUSP7 ABCA8 CCND3 IQGAP1 FEZ1 BMI1 SMPD1 KLC1 CYBA	down	*
WEI_MYCN_TARGETS_WITH_E_BOX	0.0020469	0.0202358	0.4317077	0.2657154	1.337276	698	ATP10B TRIP13 FGA HELLS NXPH4 RUVBL1 MCM10 S100A2 PDCD6 BUB1B NUP107 PPFIA4 PDCD2L GGCT MND1 CHST4 PRIM2 DEPDC1 DEPDC1B EFNA3 PRR15L ANLN NDUFS6 FLAD1 TOMM34 AURKB CENPA CDC6 E2F3 UHRF1 MCM4 RAD54B CDC25A UMPS CA12 EIF3B CCT6A MCM8 MIS18A MAP2K6 SRPK1 P2RX2 MRPS35 COQ3 CCT2 SPDL1 HMMR CISD1 DCBLD2 F2RL1 MRPL15 BUB1 CCDC77 EEF1E1 PUS7 NUP155 TMEM177 GTPBP3 MSX1 RRM2 CDCA5 NSUN2 AKAP1 MRPL27 CCDC58 L3HYPDH FAM162A SLC35G2 CHEK1 ORC6 MAD2L1 SLC25A39 DCTPP1 TIMM50 BACE2 DSCC1 GNPDA1 BLM MRPS30 PHB SYMPK ALDOA SLC25A10 CCDC138 SKP2 PARP1 THOP1 MRPL36 KIAA0556 ANAPC5 PPM1E CDK1 PABPN1 POLE2 EXOSC2 UCK2 RFWD3 BIRC5 C1orf112 GMNN OAT POLR3K DHX37 STEAP1 MRPS2 DHX33 SSX2IP DYNLL2 MRPS12 NLN NOP2 ACVR1B LAPTM4B PA2G4 KPNB1 ANKRD39 NMNAT2 DNMT1 CCNE1 YDJC PSMA5 PUS1 FNDC4 ZNF468 C1orf131 MLEC GEMIN5 MRPL4 ANP32E SAP30 PSMD2 CCT7 CDC7 YARS2 CCDC137 CENPK GEMIN6 CENPV LSG1 GOLM1 PGBD5 CHCHD1 FBXO22 RRP9 POP7 FAHD1 MRPS23 ACLY MRPL41 LRRC15 PRMT1 XRCC4 SNRPD1 MALSU1 HAUS6 RABEPK C1orf109 RCC1 LSM4 CHRNA5 ATAD2 GOSR2 GTPBP10 CKAP4 NME1-NME2 CAPN15 MRPL14 MSH2 ME1 SMARCA4 CANT1 POLR3B ABCF2 WDR4 WDR77 HK2 LPGAT1 HLCS FARSB ZWILCH ZMYND19 LLPH SNRNP70 CTTN UNKL UBAP2L SLC12A2 SMC2 POLR1B EIF4G1 POP4 NMT1 SRPRB BCAN PAICS HGS SIGMAR1 FBXO45 SFXN4 RFT1 PWP1 ENO1	up	*
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	0.0000998	0.0016261	0.5384341	-0.2179346	-1.330698	685	EREG IL17RB IL1A HMOX1 TEK IL1B NUP54 RAPGEF2 KL FYN CD44 CCL3L1 SAMHD1 RASAL2 MYD88 VAMP2 S1PR1 FGF10 MEF2A CDC42 IL1RL1 IL1RN PSMD5 CBL IL23A CD36 ANXA1 EIF4A1 TNFRSF8 CLCF1 HBEGF ADAM17 LIFR RAP1A RASGRP4 MAP3K8 IFI30 RANBP9 PAQR3 LCP1 EIF4E GATA3 IL18R1 TRAF6 HNRNPDL LAMTOR3 CRK SPTBN1 ZEB1 MCL1 PDGFA KPNA5 PTPN12 IL10 MAP2K3 STAT5A ARRB1 DUSP3 CCL22 FOXO1 BIRC2 CASP1 TRIM46 TNFSF12 PTAFR PSPN TNFSF15 STX3 SOCS2 SOCS5 CCL3 NFKB1 CDKN1A PDE3B ITGAX NKIRAS1 EPGN CXCL2 IRAK2 VIM CCL4 DUSP1 PPP2R5C PPP2R5A IL7R CA1 KPNA3 HLA-DQA1 IL24 MARK3 VWF PIAS1 HCK RPS6KA2 CD80 CNTF PPP2CA AREG IL6 SOCS3 IL2RB OASL JUN PSMA1 STAT4 JUNB IFNGR1 JAK1 DUSP8 RAPGEF1 GSTO1 PIK3R1 IRF8 GRB2 CREB1 OSM RPS6KA1 PRKACA TCP1 TNFRSF9 YWHAZ FGFR4 FOS UBB PELI1 CALM1 KLB TNFSF13 PSMD12 FOXO3 MAPK8 IRF5 PPP2CB NUP153 TGFB1 HNRNPA2B1 PEA15 TEC PDE12 DUSP5 IFNAR1 PIK3C3 CD86 IRS2 PIM1 SOD2 CCR1 ACTN2 IFNLR1 CCL20 PITPNA ICAM1 FGF2 IL18 IL18RAP LAT ARRB2 CEBPD HSP90AA1 TAB2 RIPK2 ARIH1 HSPA8 ACTB SP100 HAVCR2 BRWD1 PSME4 NUP98 KPNA4 CUL3 NFKBIA RET KIT PAK2 DUSP7 TNFSF9 FGFR1 RORA NRG1 PSMD6 MT2A IQGAP1 PSMD9 IL16 EIF4A2 NUP160 CNN2 EIF4G2 IRF2 CSF2 UBE2V1 EGR1 CD70 CSF2RB GHR TNFSF8 DUSP6	down	**
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN	0.0004709	0.0061760	0.4984931	-0.2193094	-1.327403	541	GPR15 CAT PTPRE LIPA MYD88 SLC39A8 WBP4 NFATC3 RBM7 RRAGC ASAH1 BTG2 EIF5 PBX3 PICALM ABCG1 KLF10 KLF6 LCP1 PPP2R2A ASH2L NFE2L2 LAMTOR3 CRK UBE2D3 BAG1 MCL1 ATP6V1B2 RHOB PTPN12 PPT1 SCP2 BIRC2 EPOR PTPRO PIP5K1B ITM2B MAP1LC3B MED6 ATP6V1D VRK2 GRK5 ZNF24 SPAG9 SEC24B NFKB1 RIT1 PDE3B PTPRC CTBS M6PR TAF9 CD53 RNF139 EVI2A CUL5 SLC25A32 OXSR1 TM9SF2 USP16 COPS4 ACTR2 PIAS1 RAB6A PRCP SNX3 MYLIP RBPJ ETF1 PDHX WASF2 CREM CTSS DCTN6 UTRN SF3B1 PSMA1 GABPA RAC2 CYP2A6 DNAJA1 JAK1 DHX15 IPO7 GLIPR1 IDS CREB1 HSD17B12 CAP1 AP3B1 YWHAZ RASSF2 RALB CGGBP1 DEDD ACSL1 GRSF1 RHOQ CD164 ECI2 PSMD12 ICAM2 SRSF6 PKIA AZIN1 DUSP5 GALC ATXN1 CSDE1 UTP3 DOK2 NPTN CLEC2B PDE4B CCNH SMAD2 GTF2B PITPNA PDLIM5 TNFAIP8 YAF2 SF1 CDC16 NBN DCTN4 SRP72 CYB5R4 VPS4B HSPA8 IPO5 G3BP2 ARPC5 PTEN LYST DNAJB9 ANXA11 THEMIS2 DAZAP2 LPAR6 SFPQ EMC3 CNOT8 SMAD4 RNF13 IRF2 YTHDC1 UBAP1 PXMP4 CLOCK TGOLN2 CMPK1 SLC38A2 PTDSS1 GPR137B UBE2N TRIM13 SCAF11 SLC25A40 DDX21 ZNF22 DLD PYROXD1 RCBTB2 SNRPN SKAP2 NFIL3 POLR2B RPA2 RAB1A RC3H2 RNGTT ORC4 AIMP1 CFLAR CCNC IL32 CAPN7 RPP14 NFYB MYO5A ADCY3 PNP UBE2D2 ALDH3A2 SON PUM2 CRLF3	down	**
NABA_MATRISOME_ASSOCIATED	0.0022506	0.0219536	0.4317077	-0.2217860	-1.326895	488	ANGPT4 SEMA6B SEMA3G CXCL3 CLEC1B SLPI SEMA6A EREG IL1A FCN1 FCN3 SFRP4 IL1B CLEC3B WNT4 CLEC12A BMP2 GPC5 BDNF EMCN CTSW CLEC12B CLEC10A FGF10 IL1RN IL23A SEMA6D BRINP3 ANXA1 CLCF1 BMP1 SEMA3B HBEGF ADAM17 WNT2B PLXNA2 CLEC7A MASP1 CLEC14A ANXA5 PRSS12 IFNK SERPINB9 PLXNA4 SFRP1 WNT3A ADAMTSL4 HPSE2 PDGFA NODAL CST3 IL10 MMP21 CCL22 CLEC1A TNFSF12 PSPN TNFSF15 ADAMTS9 CTSD ITIH5 CCL3 C1QTNF7 EPGN CXCL2 HPSE CCL4 SFTPD XCL2 INHBA CLEC9A ADAMTS8 C1QTNF2 INSL6 HTRA4 IL24 ANXA3 TLL1 TGFB2 MMP19 WNT9A IL17D CNTF CPAMD8 AREG IL6 MUC3A CTSS ADAMTSL2 HCFC2 SERPINB8 C1QA DHH ZFP91 SFTPB CTSZ BMP3 CSTA CLEC17A OSM SERPINB6 CXCL5 FSTL3 EGLN2 LGALS2 CST7	down	*
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN	0.0035553	0.0311566	0.4317077	-0.2330891	-1.323910	326	SLC31A2 EREG IL1A ABHD5 MCOLN1 LRRC8C LRRFIP1 SMIM12 ARRDC4 CD44 BACH1 CORO1C MYD88 ARL8B ALAS1 MKNK1 AGPAT4 TEX2 NUMB CD36 BMP1 HBEGF SBDS SGMS2 GM2A MTF1 BZW1 LUZP1 KLF10 KLF6 ABHD6 NDEL1 TUBB6 FBXO8 FABP5 SYNPO ITPRIP AHNAK PLAUR AFAP1L1 KLF7 ATL3 CDKN1A HPSE PLEKHB2 INHBA OXSR1 GPR157 N4BP1 FKBP15 NRBF2 MTPN VAMP3 SAR1A PHACTR2 PDCD6IP ANKRD9 CPEB4 RAB31 GAS2L1 HRH1 TREM1 OSTM1 RCAN1 GLIPR1 KLHL18 RAB8A LPCAT2 TINF2 SNRK ATP6V0D1 CALM1 NIPAL4 PSMD12 EHD2 EPPK1 EHD1 KCTD10 C1orf116 CDC37L1 GNAI1 FAXDC2 ANKRD13A STX12 ADAMTS15 PGGT1B	down	*
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN	0.0014647	0.0153736	0.4550599	0.2611994	1.321039	810	TRIP13 FAM201A GALNT14 RUVBL1 AK4 BDH1 RPGRIP1L COIL TRNP1 FLVCR1 MPP6 SEMA4B SLC2A1 CHST4 CCDC113 SORD ECE2 HILPDA TTC26 EBF3 ALDH18A1 SFXN1 KNOP1 UMPS EIF3B MCM8 XPO5 COQ3 COX11 WDR90 NUB1 RANBP1 MANSC1 CLPTM1L BZW2 ZNF74 DCBLD2 PUS7 NUP155 WDR3 MYO10 TMEM177 SLC29A2 POLD2 CENPW DPCD SMYD2 TTLL12 RBM28 PDCD5 GCAT AKAP1 DUSP23 SOX4 L3HYPDH ZNF530 FAM162A PSMG4 ZNF618 C7orf50 MAD2L1 SLC25A39 DCTPP1 DNAAF3 HES6 AKT2 OXER1 ETFA RAD18 MRPS30 PHB ERCC2 ALG3 MGLL SLC25A10 HSPBP1 CCDC138 SKP2 DYRK2 PES1 GEMIN4 MRPL36 CBX5 ANAPC5 HDGF UCK2 BCAS4 CCT3 GOT2 DHX37 MCAT MIR570 DHX33 GNPNAT1 POLR1C TNPO2 MRPS12 RNF207 TMEM120B ATAD3A NLN NOP2 LAPTM4B FGFR1OP STK11 PA2G4 ZNF692 RANGAP1 NRGN HSPA4L MPI POLR2H SNRNP25 TELO2 PDCD11 SCLY ZNF671 NDUFA11 PSMA5 TRMU C12orf45 MRPS34 DHODH TUBB2A PTGES2 SLC37A4 HMGN3 MORN2 COPS7B ENAH MYBBP1A MSI2 ZNF816 GEMIN5 MRPL4 KIF20B GUSBP1 NOC2L DNAJC11 CLTB RMND5B BAZ2A GEMIN6 CENPV PFAS TIMM13 GOLM1 L3MBTL2 KLHL23 DCUN1D5 CENPM TWIST1 RRP9 GPATCH4 POP7 FAM136A MRPS23 NOL6 SRRT MRPL24 PEX5 MRPL41 MED24 TMEM147 WDR35 HEATR1 LSM7 CLUH LTV1 CREB3L2 RNASET2 TIGD7 RCC1 TXNL4A AP4B1 ZDHHC11 MARCKS NEFH TSR1 PRMT5 STRBP NUP62 FARSA MRPL14 AGMAT ALMS1 RPS26 TM7SF3 SLC2A5 SCO2 DZIP3 DDX54 VDAC1 MRPS25 DOHH NME4 TUBGCP4 PDAP1 ABCF2 WDR4 WDR77 PRPF31 MLLT6 BMP8B N6AMT1 GADD45GIP1 CHMP1A MROH1 ZMYND19 ERGIC1 RDH10 MRPL21 LLPH SNRNP70 FAM118B LRG1 RHOT2 UBAP2L AURKAIP1 CIAPIN1 CLEC11A POLR1B SPR TCF3 POLR1A EARS2 ADAM15 ALG1 ANKS6 TBL3 ARMC10 SFXN4 DTD2 SLC35G1 PWP1 PPP2R5D DHRS9 RAD1 NDUFB7 RRS1 MRPS26 TMEM201 PPP1R14B ACTR5 ACSL5 IFI16 ALKBH2 TTC5 STK33 FGFBP3 DHX57 MRTO4 SLC40A1 LUC7L3 RNF126 PM20D2 KLHL42 SRM PPARGC1B MRPL12 DFFB	up	*
RAO_BOUND_BY_SALL4_ISOFORM_B	0.0011832	0.0129105	0.4550599	-0.2244831	-1.318172	399	MGAT3 CD55 CPEB2 TMOD3 CCDC88A RTN3 CITED2 FOSL1 BMPR2 GTF2I ELMO1 ZBTB2 RCHY1 IER2 EDEM1 SLC19A3 PLA2G7 B3GNT5 ENTPD1 PPP1R15B ABCG2 EMILIN2 LUZP1 RNF125 M1AP GPBP1L1 IFNK NFE2L2 SFRP1 SPTBN1 NODAL PPP3CC PTPN12 TBC1D9 MOAP1 SRSF5 BIRC2 DENND6A NOSTRIN KLF9 ANKRD10 OSTF1 SOCS5 ITPK1 GSDMA ID2 UBE2B SMAD7 ZNF706 PEF1 HES1 VCPKMT GNRH1 UFM1 SPIN1 RBPJ ARL6IP5 ETF1 SLC25A3 PPP2CA PHTF2 NSMAF LRRTM2 KIF13A DCTN6 OSBPL9 DDX17 SHOC2 RCAN1 IPO7 PNPLA8 SP3 SERPINB6 REL ZNRF3 NAA30 CGGBP1 DEDD RNF146 SLC3A2 SPRY4 MYL12A SYPL2 FAM204A ZFAND6 CHIA VAV3 ITGA9 NDUFA5 ZRANB1 TGIF1 CCP110 FEM1B TMEM230 PDLIM1 CCDC68 MEIS1 NQO2 NPTN TCF7L1 IST1 INO80 SPARCL1 TFPI RTN1 EPN2 RTN4 CXCR4 EPHA4 IPO5 PSME4 KIT B3GNT2 MTUS1 ANXA11 SFPQ CNOT8	down	*
MARTINEZ_TP53_TARGETS_UP	0.0009670	0.0110992	0.4772708	-0.2201392	-1.317605	513	SLC6A4 GPD1 WEE1 EREG HSPB7 PECAM1 LRRC8C MNDA CAT USHBP1 EMP2 CYP4B1 LIPA RAMP2 ARRDC4 LPL CD44 BAG4 MSRA MEF2A ALAS1 NR3C1 TGFBR3 NCF2 FUCA1 TGFBR2 TRIB1 PILRA SPCS3 GINM1 TXNIP CD36 STARD4 CLCF1 BMP1 NDUFAF7 BZW1 PRELP RANBP9 NLK LITAF HDC ZNF410 HIPK3 CAV2 LCP1 SERPINB9 STOM PPP3CA NR4A1 SIRPA RGCC IL18R1 SPTBN1 SRGN TCAP UBE2D3 TFRC PDGFA HIF3A MSR1 CFD TNNC1 SORBS1 LIMS1 ST3GAL2 PEG3 PRKD3 DRAM1 THBS1 CLDN5 ITIH5 CDKN1A RBMS1 ATF3 CTBS CCND2 TM6SF1 DUSP1 ALOX5AP WDR48 PINK1 HLA-DQA1 ADD1 MAPRE2 TGFB2 ZNF330 SPIN1 RBP7 HCAR3 SAR1A NSMAF ESD RAB31 SLC14A1 TYROBP RABGAP1 JAK1 PRKCE MORC3 TPP2 IP6K1 CELF2 ACSL1 MOB1A FOS RRN3 UBB PNPLA2 KLB CD74 CPA3 SORT1 ZNF521 CHPT1 PEA15 ITGA9 SERPINB1 HBP1 GNA13 LTBP1 SERINC3 MR1 PCCA SOD3 ARPP19 RXRA CCL20 AMD1 PDLIM5 MGAT2 DCTN4 RTN4 PIP4K2A CDKN1C MFAP5 CALCOCO2 NSUN4 ACTB HAVCR2 PSME4 PLGRKT TMEM109	down	*
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP	0.0047068	0.0387279	0.4070179	-0.2344187	-1.314012	302	RAB11FIP1 ACP5 KMO SC5D IL1A DCSTAMP RDX DPYSL2 FCER1A ST3GAL6 ALAS1 CD9 GAS6 RFTN1 GM2A CSRP1 CYB5A TNIP3 HSPB1 LITAF ABCG1 GLS SLC7A11 STOM AKT3 ZFYVE16 TFRC TXN ATP6V1H APOC1 CD58 EPB41L2 CCNI IL10 CCL22 KCNMA1 ACSL3 CDKN1A CDS2 CCSER2 INHBA MATK N4BP1 TBC1D4 CRIM1 BTG1 ARL6IP5 CD80 PKNOX1 RAB8B PDCD6IP VAT1 LTBP2 MAP4K4 DUOX1 RABGAP1 JAK1 CCR7 CD83 CELF2 MOB1A SLC3A2 POGLUT1 GRSF1 RUNX3 DUSP5 CD86 DYNC1LI1 CD81 KYNU TNFAIP8 IER5 ATP9B CXCR4 TRAF1 PLGRKT NEK3 CD1E FOXJ2 CYTH1 LDLR DOCK4 CREG1	down	*
REACTOME_INTRACELLULAR_SIGNALING_BY_SECOND_MESSENGERS	0.0065122	0.0495232	0.4070179	-0.2372005	-1.311701	265	EREG PPARG ADCY9 ADCY4 KL RCOR1 FYN PDE1B MYD88 FGF10 PRKAR1A IL1RL1 PSMD5 CASP9 RRAGC HBEGF NR4A1 TRAF6 LAMTOR3 AKT3 PDGFA AGO4 SNAI1 AGO3 FOXO1 PIP5K1B REST CDKN1A EPGN PPP2R5C PPP2R5A PDE1C CD80 PPP2CA ADCY2 AREG JUN PSMA1 RAC2 RHOG PIK3R1 PRKCE GRB2 CREB1 PRKACA PREX2 RNF146 FGFR4 UBB CALM1 KLB USP7 PSMD12 FOXO3 PRKCG PIK3AP1 PPP2CB STRN CD86 IRS2 CSNK2A2 PHLPP2 RNF2 FGF2 PIP4K2A PSME4 CD19 KIT PTEN FGFR1 NRG1 PSMD6 PSMD9 MAPKAP1 BMI1	down	*
NUYTTEN_EZH2_TARGETS_UP	0.0000995	0.0016261	0.5384341	-0.2074948	-1.307539	911	SLC31A2 KMO HMOX1 DENND5A ROBO4 GLIPR2 ZC3H12C CPEB2 IL1B THSD1 WNT4 LPXN PTP4A2 MIR22HG LIPA TTC7B ARRDC4 ZBTB34 BDNF EGR2 CD44 LMO2 CCDC88A SAMHD1 BACH1 ST3GAL6 BAG4 CORO1C MYADM BAIAP2 THAP2 QKI FLVCR2 MYD88 TBC1D7 BMPR2 ZCCHC2 S1PR1 MSRA SLC15A3 MAL CDC42 NCF2 GAS6 TGFBR2 RFTN1 SYNC TXNIP ANXA1 WWC2 STARD4 SLC44A2 LACTB UBL3 TM2D3 ADAM17 CLEC7A CYB5A EIF5 AHRR PBX3 ACOT2 ANXA5 REV3L ANPEP PAQR3 KLF6 MALL PTX3 CLN5 STOM MOB3C ADRB2 TMEM41B MCL1 TMEM38B CD58 PPP3CC KPNA5 CPED1 DUSP3 TLE4 FOXO1 SCP2 BIRC2 KIAA0513 PPM1K CASP1 KLF4 PAQR5 ANKRD10 DRAM1 THBS1 TMED5 STX3 DENND3 GRK5 SOCS5 CLIC4 SPAG9 ITIH5 GMPR CDKN1A UBE2E2 EPGN CXCL2 ATF3 ID2 PNRC1 ACTR3 INHBA ADIPOR2 DSE MATN2 GNAQ OXSR1 PAFAH1B1 TP53BP2 IL24 BACE1 EFR3A CNRIP1 GLB1 TDRD7 NINJ1 ARHGAP17 TMEM9B RBPJ PPP2CA DDX60L RNF149 IL6 SAR1A SGK1 PNO1 PLEKHA3 RAB8B HCFC2 OASL AQP3 CYB5R1 JUN ARL5B JUNB OSTM1 DNAJA1 NXPE3 APBB2 RCAN1 FERMT2 FYTTD1 PODXL CD83 PRKCE IDS KBTBD8 COBLL1 MORC3 OGFRL1 YWHAZ GFPT2 PXK SNX9 RHOQ AZI2 NECAB1 PKIA DAGLA UBXN2A AKIRIN2 EHD1 TCF4 PEA15 DCAF5 ZBTB1 MILR1 KCTD10 ABHD13 VAMP4 C1orf116 ATP6V1A MIA3 APLP2 SOD2 LGALS3 BRI3 CCR1 PHF11 STK40 GATA6 GNA13 ACYP2 MFSD12 CLCN6 CLEC2B POLK ETS2 GTF2B CCL20 RNF2 GEM ICAM1 ABL2 CPQ TNFAIP8 RLF FKBP1A WDR1 SERTAD1 TXNDC15 NBN XKR8 MGAT2 NT5C2 CDC42EP3 PIP4K2A TAB2 RIPK2 NLRP3 SP100 MT1M NUP98 ZDHHC21 TRAF1 SOAT1 RBMS3 S100A4 TMEM109 FDX1 FNBP4 NHLRC3 NFKBIA GLRX2 CEPT1 CTSC EDN1 TMEM87A TTC19 LYST DNAJB9 CYTH1 AIM2 KIF1B THEMIS2 NR3C2 GRB10 MT2A ZFAND2A BANK1 PMAIP1 NIPSNAP3A SPHK1 PPP1CB IRF2 CSF2 KLC1 ZFYVE26 GUSBP4 HERPUD1 SPSB1 EGR1 SERPINE1 GHR SAP18	down	**
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN	0.0023245	0.0225146	0.4317077	-0.2179911	-1.285710	464	EPAS1 SLC31A2 SASH1 PPARG CD55 GLIPR2 CPEB2 RAPGEF2 MBOAT2 PLEKHF2 KIAA1109 MYADM NEDD4L CITED2 QKI YPEL5 NEDD9 NCF2 SLCO2A1 TGFBR2 TRIB1 RFTN1 WWC2 ATP2B1 SGMS2 TACC1 PPP1R15B ABCG2 CSRP1 BTG2 MAP3K8 RNF144B ABCG1 KLF6 CLK1 ITSN2 HERC3 MCL1 PPP3CC EPB41L2 PTPN12 ROCK2 CSRNP1 SYNPO EPOR KIAA0513 TCP11L2 TSPAN12 ACSL3 COQ10B ID3 DAB2 USP2 DRAM1 SOCS2 MYO1B FAM49B MGAT4A RIT1 CDKN1A RBMS1 PNRC1 DUSP1 PINK1 DSE MATN2 HES1 ANXA3 CRIM1 LMBRD1 TGFB2 CLN8 CREBRF PHACTR2 AQP3 CYB5R1 JUN CPEB4 PDE5A MSRB3 MAP4K4 JUNB IFNGR1 RCAN1 PTGER4 FERMT2 SKIL PNPLA8 ACKR3 N4BP3 COBLL1 LPCAT2 TOM1L2 LMCD1 YPEL2 HIVEP2 MYL12A MME AKIRIN2 GSAP SERPINB1 BAZ2B PDLIM1 HBP1 STON1 KYNU GATA6 NBEAL1 KAT2B TCF7L1 TAGLN UNC13D ARAP2 LDLRAD4 PDLIM5 EPB41L5 TFPI IER5 EPHA4 RND1 BOK STAM2 LYSMD3 LIMCH1	down	*
SWEET_LUNG_CANCER_KRAS_UP	0.0047870	0.0392709	0.4070179	-0.2196027	-1.281141	393	RBP4 SLPI PPARG OSBPL1A HHEX SNX10 CLDND1 LRRFIP1 CD44 CITED2 CYB5R3 VAMP2 ARL8B MARCO BCL2A1 CD9 FUCA1 PSMD5 AVPI1 EDEM1 PLA2G7 SPG21 PCYOX1 C16orf89 ENTPD1 IFI30 LITAF HDC LCP1 SIRPA RGCC BTG3 APOC1 HMGN1 MSR1 MPEG1 BST1 PIP5K1B OSTF1 VASP THBS1 CEBPA SOCS2 PLBD1 FAM49B CTSD LAPTM5 CDKN1A COTL1 ITGAX CXCL2 AXL ID2 ADIPOR2 PPP2R5C CLIP4 HLA-DQA1 RABGGTB BTG1 RNF149 AREG CTSS TULP2 PSEN1 CYB5R1 SFTPB CTSZ TYROBP HSPA1B ATP11A AK1 CDK2AP2 ATP6V0D1 SRSF6 CD74 CHIA AZIN1 TGIF1 FPR2 ATP6V0C COL15A1 LGALS3 TOB1 ACADL ELF5 IL18 SLC34A2 ZNF143 SLC31A1 ELOVL1 CES3 PARM1 HSPA8 SOAT1 C17orf49 CTSC ETV2 CHCHD7 TNFSF9 NABP1 IQGAP1 RAP1GAP CSF2 CYBA ATP6V0A1 CSF2RB IGKV2-30 SERPINE1 C1QB CTSH DUSP6 TMEM30A C5 MAPK1 GAS5 TGOLN2 SLC38A2 NUP88	down	*
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B	0.0040644	0.0345757	0.4070179	-0.2174056	-1.272589	425	RBP4 SLC31A2 EREG SIDT2 OLR1 LRRFIP1 THBD SMIM12 HSD17B11 CD44 SOX17 CCRL2 MYADM MYD88 GPCPD1 C5AR1 CLEC10A FUCA1 SYNC GINM1 AVPI1 EDEM1 JPH2 ANXA1 SH2B3 DNAJC18 BMP1 LTBP4 HBEGF ASAH1 CHRNE CHMP1B EIF1 SERP2 BTG2 SERINC1 PICALM KLF6 RNASE1 CAV2 NR4A1 ADRB2 TMEM41B MAPK8IP1 BTG3 TFRC KRT4 MAP2K3 ROCK2 AMOTL1 AHNAK SORBS1 SAP30BP PLAUR SLC12A4 COQ10B FMO2 DRAM1 FBXL3 UBQLN1 TMBIM1 GPR85 TEF DUSP1 SMAD7 INHBA WFS1 ANXA3 CMTM6 PIAS1 HGSNAT NINJ1 AREG IL6 RGS18 UTRN CNNM2 CCDC3 INMT ETS1	down	*
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	0.0005928	0.0073547	0.4772708	-0.2077631	-1.271338	706	SLPI SIDT2 SASH1 EDNRB SECISBP2L HHEX GLIPR2 ATXN3 CAT HSD17B6 LRRFIP1 PTPRB PID1 FOLR1 CD44 TXNL1 CITED2 ELF2 INPP5A MTMR10 FBXO3 TGFBR3 NEDD9 PDE4C TSHZ1 ZBTB2 TGFBR2 TEX2 ZEB2 SNHG5 TXNIP ZBTB4 MMRN2 FBXO7 UBL3 MALAT1 PCYOX1 LIFR RAP1A CSRP1 ZDHHC2 RNF144B ABCG1 FOXP1 HIPK3 KLF6 GPBP1L1 CLN5 PPP2R2A SLAIN2 TNS1 AKT3 SPTBN1 PPP1R13B EPM2AIP1 UBE2D3 CST3 CYBRD1 CSRNP1 SNED1 PER3 AGO3 FOXO1 DENND6A TSPAN12 FAM76A HAUS2 ANKRD10 THBS1 MED6 SOCS2 EPM2A TMBIM1 FMNL3 NR1D2 TEF CD302 PNRC1 RECK LBH CCND2 WASF3 NUTM2A-AS1 PINK1 MATN2 PRICKLE2 KBTBD4 HES1 TBC1D4 ADD1 MRVI1 PIAS1 KANK1 MYLIP SLC25A3 MED28 SGK1 PHACTR2 SNAP23 RNF141 MAGI2 TMTC1 JUN LIMD1 KCTD12 LTBP2 DDX17 BTD APBB2 PTGER4 PODXL BAG5 SUGT1P3 SELENBP1 HERC1 SNX1 MSANTD2 GPRC5A SNRK WDR7 TOM1L2 RNF146 HIVEP2 MBP CD74 MARC2 CCDC152 TCF4 NDUFA5 KCTD10 TSC22D1 TPMT RELL1 ATXN1 PHF11 TOB1 STX12 SBSPON N4BP2L2 KAT2B TAGLN MBNL1 INO80D PITPNA JUND RBL2 MOB3B SESN1 GPX3 PDLIM5 CPQ TNFAIP8 EPB41L5 OPN3 SEC63 B3GALNT1 EPHA4 TAB2 FBXO30 SIK3 TOB2 ALDH2 TBC1D1 FBXO25 ACACB GPD1L BCAM RBMS3 METTL7A GLUL LIMCH1 CUL3 NFKBIA CCDC92 RNF38 ST6GAL2 PTEN LTBP3 CYTH1 ABCA8 TMCC3 HEBP1 GSPT1 EHD4 ENY2 SMAD4 SPATA13 RAP1GAP PPP1CB FNBP1 MED31 CBX7	down	**
MILI_PSEUDOPODIA_CHEMOTAXIS_DN	0.0045848	0.0381929	0.4070179	-0.2178555	-1.265101	381	LRRC8C SPNS1 NEDD4L BAIAP2 HMGCR MSLN CD9 GALNT18 SLCO2A1 TXNIP PLA2G7 SLC44A2 NCEH1 CLCF1 MAN2B1 BMP1 ASAP1 LTBP4 SEMA3B MALAT1 TM2D3 EIF1 ITGA5 SERINC1 KLF6 ADRB2 NDEL1 HNRNPDL GRN SLC19A1 ADAMTSL4 EPB41L2 ATP10A ZMIZ1 SNED1 ITPRIP PPT1 BIRC2 PPP6R3 SLC12A4 CDIP1 GAA THBS1 CDS2 AXL DUSP1 MFSD11 MATN2 HTT SLC6A6 TM9SF2 BCLAF1 DEGS1 LMBRD1 BTG1 ARHGAP17 RBM39 CCNY SOCS3 ESD LAMB2 CNNM2 C20orf194 SNX29 TMPPE ACKR3 HSD17B12 FOS ADNP2 MFSD10 USP7 FOSB TIMP2 TGIF1 APLP2 CLCN6 SERINC3 SOD3 ELOVL1 LRP12 ESYT1 HSPA8 SCPEP1 TMEM109 SREBF2 NHLRC3 TIMP3 ZDHHC5 B3GNT2 TTC19 THRAP3 TNFSF9 FGFR1 LDLR NRP2 SFPQ GSPT1 PIM3 SERPINE1 SPPL2A FADS3 TMEM43 HMGCS1 SLC19A2 LHFPL2 FUS GAS5 ITGB1 SLC38A2 ZFP36 CD109 FAM53B CCNT2 PTGS1 QSOX1	down	*
KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	0.0027907	0.0255939	0.4317077	-0.1933297	-1.194710	741	SMAD6 WEE1 OLR1 OSBPL1A CD55 TBX3 MBOAT2 THBD PTPRB COQ2 CD44 TMOD3 BACH1 RASAL2 CAV1 CORO1C NEDD4L FOSL1 QKI BMPR2 GTF2I PLEKHA1 INPP5A SFR1 C8orf58 TBC1D2 MEF2A IL1RL1 RGPD5 WBP4 CBL DENND2C HSPE1 STARD4 NCEH1 CLCF1 TRA2B B3GNT5 HBEGF MALAT1 SBDS TTL OLFML2A PLXNA2 BTG2 ACOT2 PICALM KLF10 KLF6 GLS EIF4E GATA3 PPP3CA SPTBN1 TXN MCL1 MTHFR TUBB6 KRT4 TIPARP MAP2K3 CSRNP1 AMOTL1 ITPRIP PTPN21 AHNAK CASP1 ANKRD10 SLC7A8 TJP1 THBS1 ATP6V1D KLF7 SPAG9 UBQLN1 TMBIM1 NFKB1 MARVELD1 CDKN1A COTL1 ATF3 VIM CTBS ANKRD10-IT1 CEP57 ELK3 SMAD7 ARL4A DSE DSTN CYP26B1 HES1 CALM2 ANXA3 MARK3 FAM76B HSDL2 MAPRE2 ARHGDIB BTG1 SERTAD2 KANK1 SPIN1 MOB4 RBPJ WNT9A HCAR3 WASF2 INO80C BCAR3 SNAP23 MAML2 SRSF3 SERPINB8 MITF ZFP91 LTBP2 ETS1 GLUD1 ST6GALNAC4 JUNB RABGAP1 IFNGR1 RAPGEF1 SKIL IFRD1 MBNL2 MALT1 COBLL1 YWHAZ GPRC5A DENND4A CASZ1 TAGLN2 DEDD NDST1 MORF4L1 SLC25A24 AGPS PTP4A1 RBKS FOXO3 MAPK8 RIN2 BTBD7 SAV1 AKIRIN2 HNRNPA2B1 TCF4 TGIF1 CCP110 TSC22D1 FEM1B C1orf116 CTNNAL1 PDLIM1 PIM1 ATXN1 GNG5 PHF19 HNRNPH3 LGALS3 NQO2 GABARAPL1 NPTN MFSD12 ETS2 MBNL1 IST1 HELZ MOB3B IL18 ZNF143 FKBP1A EPN2 BLOC1S2 RTN4 CDC42EP3 USPL1 UBE2D1 HNRNPK EPHA2 KPNA4 STAM2 BCAT1 SIN3A COPS8 JMJD1C MAFK EDN1 TMEM87A LTBP3 MT2A GSPT1 WDFY3 EIF4A2 RNH1 PURB	down	*
NABA_MATRISOME	0.0064303	0.0490358	0.4070179	-0.1930945	-1.180444	697	TNR ANGPT4 SEMA6B SEMA3G CXCL3 CLEC1B SLPI SEMA6A EREG COL25A1 IL1A FCN1 FCN3 SFRP4 IL1B CLEC3B WNT4 CLEC12A BMPER BMP2 GPC5 BDNF MMRN1 HMCN2 EMCN CTSW CLEC12B PCOLCE2 CLEC10A FGF10 IL1RN GAS6 IL23A HSPG2 SEMA6D BRINP3 ANXA1 MMRN2 CLCF1 BMP1 LTBP4 SEMA3B HBEGF ADAM17 WNT2B PLXNA2 CLEC7A EMILIN2 MASP1 CLEC14A PRELP ANXA5 PRSS12 IFNK SERPINB9 PLXNA4 SFRP1 WNT3A SRGN ADAMTSL4 HPSE2 PDGFA NODAL CST3 GLDN IL10 MMP21 SNED1 CCL22 NPNT CLEC1A TNFSF12 PSPN TNFSF15 THBS1 ADAMTS9 CTSD ITIH5 LAMC3 CCL3 C1QTNF7 EPGN CXCL2 HPSE CCL4 IGFBP2 SFTPD XCL2 INHBA CLEC9A MATN2 ADAMTS8 C1QTNF2 INSL6 HTRA4 IL24 ANXA3 CRIM1 TLL1 VWF TGFB2 MMP19 TECTA WNT9A IL17D CNTF CPAMD8 AREG IL6 MUC3A CTSS ADAMTSL2 PODN HCFC2 LAMB2 NDNF SERPINB8 C1QA DHH ZFP91 LTBP2 SFTPB CTSZ BMP3 CSTA CLEC17A OSM SERPINB6 MFAP4 LGI4 CXCL5 FSTL3 EGLN2 LGALS2 COL23A1 CST7	down	*

C3 regulatory target genes Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
HSD17B8_TARGET_GENES	0.0000000	0.0000000	1.4675240	0.4991347	2.465407	484	MCIDAS TRIP13 FOXM1 KIF20A HJURP CEP89 TICRR PARPBP MCM10 FANCI ZNF273 C1QTNF6 TROAP CHEK2 BUB1B NUP107 NEK2 CENPF POLQ UBE2T C21orf58 MND1 PBK KIF18B TTF2 NDC80 PRIM2 DEPDC1 IFI27L1 BRCA1 CDCA7 ZNF138 TTK GINS1 C6orf141 CDCA2 AGFG2 IQGAP3 E2F8 GTSE1 DBF4B KIF14 ANLN TRAIP DNMT3B POLE ASPM STIL ANKRD24 BAMBI CR1L DGCR8 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 E2F3 CCNB2 NBR2 GLB1L3 UHRF1 CDC25A MYBL2 PRC1 XRCC2 KCNMB4 DTL TDRKH MCM8 MIS18A RCCD1 ZWINT P2RX2 ZNF107 LSM5 ZNF726 AARS2 WDR62 C5orf34 CCDC150 ZNF730 MELK HMMR EXO1 C19orf48 KIF23 CEP55 RPL39L FOXA1 MKI67 KIF15 AP4M1 KNTC1 RHNO1 BUB1 TOP2A EME1 THBS4 KIF2C MCM7 E2F2 CENPW POC1A RSRC1 ANKRD19P RRM2 CDCA5 HOXC6 RAD54L MRPL27 FANCD2 GPSM2 MCM3 C7orf57 CDC25C ZNF785 ZNF530 BRD9 ABCB6 TOPBP1 ZYG11A MAD2L1 CKAP2L CENPO RAD51AP1 THAP10 SPC24 BRIP1 RAD18 BLM LRRC45 FADS2 TULP3 LEF1-AS1 INCENP CKS1B NCAPG2 CDKN2C C12orf75 ASF1B CDK1 RFWD3 BIRC5 ATP2A1 C1orf112 NUDT2 E2F1 UNG NCAPG DNA2 SPAG6 FEN1 SPAG5 THAP8 MTBP ATAD3A DIAPH3 RECQL4 CENPP C9orf43 FGFR1OP RNASEH2A NET1 LGR5 ZNF687 INTS7 CCNE1 CEP192 CDC23 DLGAP5 SATB2 FAM47E-STBD1 TACC3 MNS1 KIF22 UBE3D FBXO15 TK1 CHTF18 CENPQ ESCO2 GINS2 ANP32E TCEA1 KIF20B C15orf41 POLD1 CEP128 ATAD5 CENPK SASS6 CKAP5 BRD8 COG1 CDC20 RPA1 RPUSD1 FANCM MCM6 HOXA3 MCM5 RPPH1 TDP1 C1orf109 GINS3 DOLPP1 RCC1 CDH11 ATAD2 CEP152 TCERG1 ALG8 LRRC14 ZNF519 CCNA2 RBM42 DZIP3 PRR11 ZNF90 SNRPD2 ZNF66 SHCBP1 RFC5	up	***
MIR8074	0.0003211	0.0075349	0.4984931	-0.6730528	-2.155710	16	ZBTB34 ROCK2 FOXO1 ADO UBQLN1 NRBF2 RORA NRP2 EVI5 RMDN1 MAN1A1	down	**
MIR2861	0.0000125	0.0006243	0.5933255	0.5004556	2.017406	76	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA7 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 SYT12 PCDHGA12 PCDHGC5 PCDHGC4 YKT6 E2F2 HOXC6 PCDHGA4 PCDHGB7 PCDHGA3 MGLL TMEM120B PCDHGA2 STOML1 SEMA4G CHD5 PCDHGB1 FIBCD1 CHTF8 KIF21B POLR2J3	up	***
MIR711	0.0003098	0.0073621	0.4984931	-0.5096927	-1.994755	36	GATA2 WNT4 MYD88 TBXA2R SLC36A4 BNIPL CREBRF SYNPO2 NECAP1 C2CD2 TMEM230 DUSP5 C16orf72 MEX3C PAK2 SKI	down	**
MIR1269A_MIR1269B	0.0000562	0.0019963	0.5573322	0.5479084	1.979080	43	PCDHGA10 ZNF84 PCDHGA9 PCDHGA5 PCDHGA7 SLC25A21 PCDHGA1 PCDHGB3 PCDHGA11 PCDHGA8 PCDHGA12 RHOBTB3 PCDHGB7 PCDHGA3 BRIP1 URI1 PCDHGA2 UBFD1 ZNF160 ANKIB1 RER1 GLO1	up	**
SRF_C	0.0000001	0.0000209	0.7049757	-0.3717745	-1.976316	183	MIR22HG EGR2 FOSL1 ANAPC15 IER2 ZEB2 JPH2 KCNK3 EMILIN2 FOXP1 KLF6 LCP1 NR4A1 CRK CNN1 UNC45B ROCK2 TNNC1 TRIM46 AOC3 THBS1 MYO1B KCNMB1 ACTR3 DSTN ACTG2 MYH11 MRVI1 SRF TRIM55 MITF JUNB RHOJ LYRM1 HERC1 OSM CAP1 YWHAZ RASSF2 GFPT2 MCAM FOS LMCD1 KRTCAP2 FOSB DUSP5 TGFB1I1 C16orf72 MEIS1 MRGPRF LTBP1 TAGLN MBNL1 PDLIM5 DIXDC1 PTCH1 ACTB G3BP2 CNN2 RSU1 STARD13 KALRN EGR1 CDC14A CFL2 DUSP6 DCUN1D3 YRDC DNAJB4 LDB3 PLN AKAP12 MATR3 SETD2 DACT3 DUSP2 NKX2-1 MYL9 FBXL22 MYLK SLC2A4 SPAG7 ANXA6 TANK	down	***
SRF_01	0.0003935	0.0087399	0.4984931	-0.4793567	-1.962704	43	EGR2 FOSL1 IER2 TNNC1 THBS1 KCNMB1 ACTR3 ACTG2 MYH11 MRVI1 JUNB CAP1 FOS FOSB TGFB1I1 WDR1 DIXDC1 CNN2 EGR1	down	**
PER1_TARGET_GENES	0.0010685	0.0172581	0.4550599	-0.5354569	-1.951980	25	SNORD12 SNORD12B SNORA81 RABGGTB RPL17 RBM39 SGK1 RPL21 HNRNPK SFPQ EIF4A2 HNRNPH1 SNRPG GAS5 SLC38A2 PNRC2 SNORA63	down	*
MIR122B_3P	0.0000136	0.0006680	0.5933255	-0.3926124	-1.942020	104	GCOM1 ZC3H12C CPEB2 RDX HSD17B11 RTN3 LAMP1 SRSF2 HERC3 GPM6A CDADC1 PEG3 RUNX1T1 C9orf72 KIRREL3 SMAD7 TOPORS PSEN1 APPL1 WTAP FYTTD1 RC3H1 SNRK CDK14 CDK17 FOXO3 CCDC85A NAP1L5 BTBD7 ING3 PDE4B TIAM1 POLR2M PRKG1 MMD CAMSAP2 ZNF326 USP4 CHIC2 TMEM43 ZNF800 ATP1B1 DNAJB4 TSC22D2 MAP3K1	down	***
MIR21_3P	0.0000111	0.0005921	0.5933255	-0.3931281	-1.927160	102	GCOM1 ZC3H12C CPEB2 RDX HSD17B11 RTN3 LAMP1 SRSF2 HERC3 GPM6A CDADC1 PEG3 RUNX1T1 C9orf72 KIRREL3 SMAD7 TOPORS PSEN1 APPL1 WTAP FYTTD1 RC3H1 SNRK CDK14 CDK17 FOXO3 CCDC85A NAP1L5 ING3 PDE4B TIAM1 POLR2M PRKG1 MMD CAMSAP2 ZNF326 USP4 CHIC2 TMEM43 ZNF800 ATP1B1 DNAJB4 TSC22D2 MAP3K1	down	***
MIR7844_5P	0.0000041	0.0002974	0.6105269	-0.3780337	-1.914002	127	RTKN2 ABHD5 P2RY1 ST3GAL6 HMGCR PRKAR1A ZEB2 STARD4 ZNF385D ASAP1 PPP1R15B RAB33B IFI30 RNF182 PTX3 NFE2L2 CRK ZEB1 ZNF24 DOCK9 VIM FRMD4A CAPZA2 ELK3 ZMPSTE24 TMEM9B METAP1 EBF2 ELOVL7 SNX2 STX7 SKIL FSD1L NAA30 CELF2 CTTNBP2 MAPK8 ABHD13 SCARA5 RIMKLB LDLRAD4 EPN2 LRP12 CYB5R4 EPHA4 MEX3C CTSC RAB2A MIER3 HERPUD1	down	***
MIR6090	0.0016067	0.0227925	0.4550599	-0.7676573	-1.899946	8	ADCY9 DDX6 DSE ATL2 CDK14	down	*
MIR92A_1_5P	0.0003562	0.0081525	0.4984931	0.5419297	1.893773	38	FBXO27 WFDC2 SLC2A1 SIX4 FCGR3B PRKCA ACY1 TNC LMLN ODF2 CXCL9 COL1A1 MSI2 S100A9 CEP128 PPME1 SH3TC2 AKAP6 HDLBP BBX MLLT6	up	**
CTTGTAT_MIR381	0.0000010	0.0001091	0.6435518	-0.3559298	-1.885957	172	WEE1 DLC1 INSIG1 DDX6 QKI GTF2I SEMA6D UBR3 CLCF1 B3GNT5 EIF1 NLK ROCK2 ACSL3 KLF4 CEBPA UBE2E2 PNRC1 KPNA3 SIAH1 CREBRF ETF1 MITF HMBOX1 ETS1 JPH1 ELOVL7 MBNL2 RC3H1 CGGBP1 SNRK RHOQ NAP1L5 BTBD7 EPHA3 AZIN1 PDS5B KHDRBS1 CNOT7 HBP1 ANKRD12 STX12 PHF2 RNF2 CXCR4 EPHA4 SSH2 NFKBIA KIF1B ITCH ZFPM2 RNF13 RAB2A EIF4G2 MAP4 PSIP1 KALRN HIPK1 DCUN1D3 SLC38A2 CCNT2 XPO7 WNT5A UBE3A MTSS1 RNF111 NR5A2 RAB11FIP2 ARGLU1 SRRM1 SCAF8 SLC24A3 GRM8 JAG2 PDS5A MED13 UBE4A PRPF38B APPBP2 ZNF770 GID4 KLF12 PAPOLG BCL11B	down	***
GTATGAT_MIR154_MIR487	0.0002782	0.0068748	0.4984931	-0.4183108	-1.861174	61	DYRK1A RHOA ZEB2 NLK CLK1 PDE4D GPM6A AGO4 KCNMA1 SMAD7 KPNA3 CREBRF MAGI2 SP3 RC3H1 TSHZ3 AZIN1 GALC NPTN IFFO1 TMEM184B RNF38 ENY2 BMI1 YTHDC1	down	**
MIR4740_5P	0.0003965	0.0087538	0.4984931	0.4803781	1.833995	59	PCDHGA10 ELOVL6 ZNF84 PCDHGA9 PCDHGA5 PCDHGA7 SLC25A21 PCDHGA1 PCDHGB3 P2RX2 PCDHGA11 PCDHGA8 PCDHGA12 PCDHGB7 PCDHGA3 URI1 PCDHGA2 PSMA5 KCNIP3 ACLY RER1 GLO1	up	**
CTR9_TARGET_GENES	0.0012769	0.0196053	0.4550599	-0.4358592	-1.827783	49	SLPI TMEM138 SRSF7 ALAS1 CCNL1 ZEB2 EDEM1 TRA2B HNRNPU FBXL5 TAPT1 RBM39 RPL9 SNX22 YWHAZ TLDC2 CSDE1 BAG6 AMD1 TPT1 HNRNPC SFPQ	down	*
MIR25_3P	0.0000000	0.0000011	0.7749390	-0.3159974	-1.824032	358	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 MED19 SLC7A11 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 KBTBD8 MORC3 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 ZNF521 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 MEF2D ZFYVE21 ITGA6 ROBO2 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1 NFYB MYO5A ADCY3 ANKRD44 ADAM19 MFHAS1 SLC24A3 PNISR PSMD14 KLHL29 PIK3R3 RBM27 ANKRD28 ZC2HC1A AIDA GTF2A1	down	***
MIR3688_3P	0.0000000	0.0000051	0.7477397	-0.3160464	-1.815125	341	RTKN2 ZNF366 OTUD7A FOXF1 GPR15 ZC3H12C ATXN3 ADCY9 KCTD9 OTUD1 MMRN1 PLEKHF2 CCDC88A LDB2 NEDD4L CDH13 BMPR2 YPEL5 ACER3 HSPE1 CYP17A1 B3GNT5 SLC2A14 LTBP4 UBL3 TACC1 C1orf21 RANBP9 SPIRE1 ZBTB21 FOXP1 GLS STOM PLXNA4 CD93 HNRNPU TMEM38B ROCK2 CSRNP1 MOAP1 PEG3 FAM76A LEPROTL1 USP2 STK17B RIT1 EPGN CXXC4 SHE MPC1 GNAQ PRICKLE2 TM9SF2 SMNDC1 CNOT6L RASGEF1B PIAS1 SRGAP2C SLC8A1 CD80 MAGI2 SRSF3 SH3BP5 GABPA DESI2 SHOC2 APBB2 VPS26A SKIL GLIPR1 CREB1 KBTBD8 ATP13A3 HOMER1 NAA30 EPC2 FOS PSMD12 ZFAND6 VAV3 AP1G1 ITGA9 TGIF1 VAMP4 RSBN1L MIA3 NFYC ATXN1 SBSPON CSNK2A2 SERINC3 FAM98B INO80D CCL20 RNF2 MIER1 LMOD1 BLOC1S2 LRP12 HNRNPK G3BP2 SRSF10 MARC1 JMJD1C PAK2 CECR2 RORA DCUN1D2 SCLT1 MAP4 ABI1 UBE2V1 PLAG1 UBR2 CFL2 DKK3 CAPZB LHFPL2 MYH10 DYNC1I2 FAR1 COX20 PPIP5K2 DPF3 API5 UBE3A SGPP1 PCDH15 ATP2B4 SLC23A2 WDR26 RAB1A UEVLD SIRT1	down	***
MIR1284	0.0000037	0.0002797	0.6272567	-0.3362317	-1.804873	191	CD55 CPEB2 ST6GALNAC3 BDNF STXBP6 WBP4 ZBTB2 CD8A EIF4A1 UBL3 NLK REV3L KLF6 CAMTA1 ZNF697 ADRB2 EPB41L2 SNAI1 SORBS1 PPM1K ACSL3 REST UBQLN1 ID2 CAPZA2 PIK3C2A WDR48 PPP2R5C PDE1C MARK3 FAM76B PIAS1 ID4 KIF13A HCFC2 SF3B1 MCM9 FYTTD1 SKIL PCGF5 DENND4A SPRY4 KAT8 TSHZ3 DAGLA NUP153 PDS5B PDLIM1 ATXN1 INO80D HACE1 RNF2 LDLRAD4 FKBP1A CTTNBP2NL TAB2 UBE2D1 SP100 CREBBP SRSF10 RORA LDLR ZFPM2 KALRN PEX14 SVIL SLC19A2 OSGIN2 RB1CC1 KMT2E SGIP1 TSC22D2 HMGB1 RNF214 ARHGEF12 TES EP300	down	***
CGTCTTA_MIR208	0.0045841	0.0466025	0.4070179	-0.7270381	-1.799414	8	QKI NLK ETS1 SP3 CSNK2A2 MIER3	down	*
ATGTTAA_MIR302C	0.0000013	0.0001342	0.6435518	-0.3349775	-1.799335	201	EDNRB CPEB2 PTP4A2 PTPRE ST6GALNAC3 BMP2 TTC7B FAM49A NUMB ZBTB4 UBR3 KIAA0355 NFIX B3GNT5 HBEGF LIFR FZD4 FOXP1 DACH1 SRSF2 PDE4D RAB14 ATP6V1B2 ATP10A ZMIZ1 MTMR6 SRSF5 ZCCHC24 MYO1B GAPVD1 FBXL3 UBQLN1 C1QTNF7 ELMSAN1 ARL4A TLL1 RBM39 METAP1 CREM PHACTR2 SF3B1 PPA2 GABPA OSM CGGBP1 EPC2 UBB SPOP AZIN1 NUP153 HNRNPA2B1 STRN SBF2 ATP6V1A IRS2 PPP3R1 TOB1 ANKRD12 KANSL2 MBNL1 RNF138 NRP2 NR3C2 ZFPM2 EIF4A2 SMAD4 RNF13 EHD3 SLC35A1 HNRNPH1	down	***
MIR6757_3P	0.0003028	0.0072507	0.4984931	-0.3820284	-1.786884	81	SEMA6A USP12 EGR2 LDB2 PSMD5 UBL3 TTYH2 PPP2R2A GPM6A ATP6V1B2 PPP6R3 ARNTL SPAG9 KCTD20 N4BP2L1 ADD1 SIAH1 CPEB4 RC3H1 AZIN1 AKIRIN2 VAMP4 ATP6V1A ATXN1 CLASP2 MBD5 TBCEL SIN3A CAMSAP2 RORA	down	**
MIR200B_3P	0.0000000	0.0000005	0.8012156	-0.3050469	-1.783473	419	SLC24A4 RTKN2 NOVA2 FOXF1 DLC1 DENND5A OSBPL11 TRHDE SECISBP2L RDX MBOAT2 TMOD3 CORO1C VAT1L THAP2 QKI AKAP7 NR3C1 OTUD4 CBL SCN5A TMX4 ZEB2 ERG SEMA6D KIAA0355 DNAJC3 ASAP1 SERINC1 RANBP9 PICALM HIPK3 KLF6 PAG1 DACH1 KANK2 ZEB1 ZYG11B GPM6A FLI1 CPED1 PTPN12 ROCK2 PRDM16 PTPN21 CCDC82 KLF4 ZCCHC24 CLIC4 SPAG9 RECK WASF3 DUSP1 ELK3 ADIPOR2 GNAQ LIN7A AFF3 USP25 PDIK1L PHTF2 PIKFYVE JUN NOTCH1 HMBOX1 SLC14A1 ETS1 MAP4K4 OSTM1 FOXN2 TBC1D12 FERMT2 IPO7 HSPA13 PI4K2B MBNL2 ATL2 FSD1L CASZ1 PPM1F GAS2L3 AGFG1 CDK17 YPEL2 PKIA NAP1L5 ZFAND6 HNRNPD TIMP2 STRN PDS5B TSC22D1 KHDRBS1 NAB1 C16orf72 ATXN1 TOB1 KYNU CLASP2 SBSPON POLK ATAD2B RNF2 GEM SESN1 VASH1 XKR8 MGAT2 IER5 MFAP5 TRAPPC8 RIPK2 FBXO30 ARIH1 DIXDC1 ZDHHC21 ULK2 STK4 RASSF8 COPS8 SCAI B3GNT2 CECR2 DNAJB9 FAM126B PRKG1 CYTH1 MMD CAMSAP2 NRG1 ZFPM2 DNAJB5 EVI5 FEZ2 PMAIP1 ZNF326 REEP1 PSIP1 EXOG CRTAP CFL2 CLIP1 GJC1 HIPK1 FAM8A1 NOG CSNK1G3 CTDSPL2 YWHAB PRTG PPFIA1 UBE2W SGIP1 TSC22D2 MATR3 ADH1B MAP3K1 CNTN1 CCNYL1 NR5A2 RAB11FIP2 MPDZ LRP1 PKD1 MAPK7 SYDE1 NTF3	down	***
MIR200C_3P	0.0000000	0.0000005	0.8012156	-0.3050469	-1.783473	419	SLC24A4 RTKN2 NOVA2 FOXF1 DLC1 DENND5A OSBPL11 TRHDE SECISBP2L RDX MBOAT2 TMOD3 CORO1C VAT1L THAP2 QKI AKAP7 NR3C1 OTUD4 CBL SCN5A TMX4 ZEB2 ERG SEMA6D KIAA0355 DNAJC3 ASAP1 SERINC1 RANBP9 PICALM HIPK3 KLF6 PAG1 DACH1 KANK2 ZEB1 ZYG11B GPM6A FLI1 CPED1 PTPN12 ROCK2 PRDM16 PTPN21 CCDC82 KLF4 ZCCHC24 CLIC4 SPAG9 RECK WASF3 DUSP1 ELK3 ADIPOR2 GNAQ LIN7A AFF3 USP25 PDIK1L PHTF2 PIKFYVE JUN NOTCH1 HMBOX1 SLC14A1 ETS1 MAP4K4 OSTM1 FOXN2 TBC1D12 FERMT2 IPO7 HSPA13 PI4K2B MBNL2 ATL2 FSD1L CASZ1 PPM1F GAS2L3 AGFG1 CDK17 YPEL2 PKIA NAP1L5 ZFAND6 HNRNPD TIMP2 STRN PDS5B TSC22D1 KHDRBS1 NAB1 C16orf72 ATXN1 TOB1 KYNU CLASP2 SBSPON POLK ATAD2B RNF2 GEM SESN1 VASH1 XKR8 MGAT2 IER5 MFAP5 TRAPPC8 RIPK2 FBXO30 ARIH1 DIXDC1 ZDHHC21 ULK2 STK4 RASSF8 COPS8 SCAI B3GNT2 CECR2 DNAJB9 FAM126B PRKG1 CYTH1 MMD CAMSAP2 NRG1 ZFPM2 DNAJB5 EVI5 FEZ2 PMAIP1 ZNF326 REEP1 PSIP1 EXOG CRTAP CFL2 CLIP1 GJC1 HIPK1 FAM8A1 NOG CSNK1G3 CTDSPL2 YWHAB PRTG PPFIA1 UBE2W SGIP1 TSC22D2 MATR3 ADH1B MAP3K1 CNTN1 CCNYL1 NR5A2 RAB11FIP2 MPDZ LRP1 PKD1 MAPK7 SYDE1 NTF3	down	***
MIR1233_3P	0.0005983	0.0116867	0.4772708	0.4478516	1.780199	69	KCNMB2 PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA7 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 CCL28 PCDHGA2 FAH PDRG1 TRIM32 PCDHGB1	up	*
MIR10525_3P	0.0009117	0.0154449	0.4772708	0.4746119	1.775502	51	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA7 PCDHGA1 PCDHGB3 PCDHGA11 PCDHGA8 RANBP1 PCDHGA12 PCDHGB7 PCDHGA3 PCDHGA2 HMGN3 TJAP1 KIF20B SLX4IP ACLY ANKIB1	up	*
MIR363_3P	0.0000000	0.0000057	0.7337620	-0.3066581	-1.773999	363	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 MED19 SLC7A11 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 KBTBD8 MORC3 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 ZNF521 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 FAM126B MMD C21orf91 RORA EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 MEF2D ZFYVE21 ITGA6 ROBO2 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1 NFYB MYO5A ADCY3 ANKRD44 ADAM19 MFHAS1 SLC24A3 PNISR PSMD14 KLHL29 PIK3R3 RBM27 ANKRD28 ZC2HC1A AIDA GTF2A1	down	***
MIR938	0.0010049	0.0163729	0.4550599	-0.3949533	-1.768891	66	EPAS1 ZBTB34 SFR1 SLC11A1 MOB1B TRIB1 RCHY1 BZW1 HNRNPA3 DENND6A USP25 PRCP CREBRF MSRB3 IRF8 SDHD WDFY4 SLC8A3 CPT2 NPTN PRDM8 TIAM1 SSH2 SHISA6	down	*
ATACTGT_MIR144	0.0000107	0.0005765	0.5933255	-0.3337019	-1.768179	172	SEMA6A CPEB2 ST6GALNAC3 CCDC88A CALCRL QKI ZCCHC2 NR3C1 TRIB1 ZEB2 SEMA6D UBR3 ATP2B1 LIFR EIF5 CAV2 SLC7A11 GATA3 NFE2L2 SFRP1 CLK1 HNRNPU ITSN2 PDE4D UBE2D3 TFRC FOXO1 FBXL3 PNRC1 PAFAH1B1 FAM76B MTPN CREBRF PKNOX1 PHTF2 ETS1 JPH1 WTAP KBTBD8 CELF2 PTP4A1 FOSB RIN2 CC2D2B KIAA0232 PIM1 ATXN1 PPP3R1 MEIS1 SRSF10 SIN3A FAM126B NRP2 NAA15 GSPT1 WDFY3 PUM1 EIF4G2 HAT1 PLAG1	down	***
MIR152_3P	0.0000001	0.0000243	0.6901325	-0.3111567	-1.767975	297	EPAS1 PNPLA6 FOXF1 TEK OSBPL11 SECISBP2L LIPA SIK1 DDX6 QKI GPCPD1 ZCCHC2 MTMR10 S1PR1 ARL8B OTUD4 EOGT TXNIP HECW2 ADAM17 ITGA5 KLF6 ITSN2 UBE2D3 TFRC RAB14 GPM6A AGO4 NRARP KLF4 LEPROTL1 ROCK1 MAFG EPM2A MPL ITPK1 CADM1 EPS15 DUSP1 PIK3C2A CUL5 PEAK1 PRICKLE2 PDE1C TANC1 NCOA1 TGFB2 SNN TMEM9B ADCY2 VPS37A PHACTR2 MTMR14 MITF BMP3 CNTN4 ATP11A MTMR9 ZNF804A FAM43A RC3H1 HOMER1 TRAK2 GPRC5A CASZ1 WDFY4 AGFG1 ITGA9 PHF3 KIAA0232 BAZ2B SBF2 SKIDA1 MMP15 ATXN1 NPTN ADAMTS15 LTBP1 PLAA CLCN6 ADAM10 DOCK6 MIER1 INO80 EPN2 RTN4 CYB5R4 MAP3K4 ING2 RASSF8 RNF38 MMD CAMSAP2 CNTNAP3B LDLR FEZ2 USP48 ZFYVE26 STARD13 CDC14A CFL2 CDKN1B TGOLN2 EYA3 NOG EFNB2 YWHAB SRSF11 SPTY2D1 WDR47 ARHGEF12 ATP8A1 ATP2B4	down	***
MIR148A_3P	0.0000001	0.0000243	0.6901325	-0.3108536	-1.766252	297	EPAS1 PNPLA6 FOXF1 TEK OSBPL11 SECISBP2L LIPA SIK1 DDX6 QKI GPCPD1 ZCCHC2 MTMR10 S1PR1 ARL8B OTUD4 EOGT TXNIP HECW2 ADAM17 ITGA5 KLF6 ITSN2 UBE2D3 RAB14 GPM6A AGO4 NRARP KLF4 LEPROTL1 ROCK1 MAFG EPM2A MPL ITPK1 MGAT4A CADM1 EPS15 DUSP1 PIK3C2A CUL5 PEAK1 PRICKLE2 PDE1C TANC1 NCOA1 TGFB2 SNN TMEM9B ADCY2 VPS37A PHACTR2 MTMR14 MITF BMP3 CNTN4 ATP11A MTMR9 ZNF804A FAM43A RC3H1 HOMER1 TRAK2 GPRC5A CASZ1 WDFY4 AGFG1 ITGA9 PHF3 KIAA0232 BAZ2B SBF2 SKIDA1 MMP15 ATXN1 NPTN ADAMTS15 LTBP1 PLAA CLCN6 ADAM10 DOCK6 MIER1 INO80 EPN2 RTN4 CYB5R4 MAP3K4 ING2 RASSF8 RNF38 MMD CAMSAP2 CNTNAP3B LDLR FEZ2 USP48 ZFYVE26 STARD13 CDC14A CFL2 CDKN1B TGOLN2 EYA3 NOG EFNB2 YWHAB SRSF11 SPTY2D1 WDR47 ARHGEF12 ATP8A1 ATP2B4	down	***
SRF_Q5_01	0.0000125	0.0006243	0.5933255	-0.3330153	-1.761817	176	PPARG TMEM126A LRRFIP1 EGR2 CORO1C MYADM CITED2 IER2 KCNK3 CSRP1 EMILIN2 PICALM FOXP1 KLF6 LCP1 CNN1 TRIM46 YBX3 VASP THBS1 NPR3 ATF3 ACTR3 DSTN ACTG2 MYH11 SRF GPBP1 SGK1 PODN MITF JUNB RHOJ CXCL5 RASSF2 COL23A1 FOS KRTCAP2 FOSB DGKG FLNC AKIRIN2 DUSP5 TGFB1I1 C16orf72 MRGPRF TAGLN MBNL1 PDLIM5 DIXDC1 PTCH1 ACTB G3BP2 TIMP3 CNN2 RSU1 ATF4 STARD13 EGR1 CFL2 CDKN1B FAM131B SVIL ADAMTSL1	down	***
MIR429	0.0000000	0.0000011	0.7749390	-0.2978713	-1.759318	428	SLC24A4 RTKN2 NOVA2 FOXF1 DLC1 DENND5A OSBPL11 TRHDE SECISBP2L RDX MBOAT2 TMOD3 CORO1C VAT1L THAP2 QKI AKAP7 NR3C1 OTUD4 CBL SCN5A TMX4 ZEB2 ERG SEMA6D KIAA0355 DNAJC3 ASAP1 SERINC1 RANBP9 PICALM HIPK3 KLF6 PAG1 DACH1 KANK2 ZEB1 ZYG11B GPM6A FLI1 CPED1 PTPN12 ROCK2 PRDM16 PTPN21 CCDC82 KLF4 ZCCHC24 CLIC4 SPAG9 RECK WASF3 DUSP1 ELK3 ADIPOR2 GNAQ LIN7A AFF3 USP25 PDIK1L PHTF2 PIKFYVE JUN NOTCH1 HMBOX1 SLC14A1 ETS1 MAP4K4 OSTM1 FOXN2 TBC1D12 FERMT2 IPO7 UBAC2 HSPA13 PI4K2B MBNL2 ATL2 FSD1L CASZ1 PPM1F GAS2L3 AGFG1 CDK17 YPEL2 PKIA NAP1L5 ZFAND6 HNRNPD TIMP2 STRN PDS5B TSC22D1 KHDRBS1 NAB1 C16orf72 ATXN1 TOB1 KYNU CLASP2 SBSPON POLK ATAD2B RNF2 GEM SESN1 VASH1 XKR8 MGAT2 IER5 MFAP5 TRAPPC8 RIPK2 FBXO30 ARIH1 DIXDC1 ZDHHC21 ULK2 STK4 RASSF8 COPS8 SCAI B3GNT2 CECR2 DNAJB9 FAM126B PRKG1 CYTH1 MMD CAMSAP2 NRG1 ZFPM2 DNAJB5 EVI5 FEZ2 PMAIP1 ZNF326 REEP1 PSIP1 EXOG CRTAP CFL2 CLIP1 GJC1 HIPK1 FAM8A1 NOG CSNK1G3 CTDSPL2 YWHAB PRTG PPFIA1 UBE2W SGIP1 TSC22D2 MATR3 ADH1B MAP3K1 CNTN1 CCNYL1 NR5A2 RAB11FIP2 MPDZ LRP1 PKD1 MAPK7 SYDE1 NTF3 GPATCH2L ANKRD44 FBXO33 PLXNC1 PUM2 YAP1	down	***
MIR4645_3P	0.0005359	0.0109252	0.4772708	-0.3645527	-1.758775	90	CPEB2 TTC7B YPEL5 MEF2A SYS1 RHOA LATS2 RAP1A AKT3 CYBRD1 ADO MYRIP ELK3 RBM44 CALM2 MAGI2 PDCD6IP GABPA ZFP91 DESI2 DUSP8 MBNL2 AP3B1 HINT3 MACF1 ADAM10 ABL2 LRP12 RAPGEF3 SAMSN1 NRG1 PUM1 CSF2RB TSTD3 SLC38A2 AQR	down	*
MIR367_3P	0.0000000	0.0000083	0.7195128	-0.3037946	-1.757679	364	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 MED19 SLC7A11 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 KBTBD8 MORC3 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 ZNF521 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 FAM126B MMD C21orf91 RORA EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 MEF2D ZFYVE21 ITGA6 ROBO2 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1 NFYB MYO5A ADCY3 ANKRD44 ADAM19 MFHAS1 SLC24A3 PNISR PSMD14 KLHL29 PIK3R3 RBM27 ANKRD28 ZC2HC1A AIDA GTF2A1	down	***
MIR3138	0.0017518	0.0240288	0.4550599	-0.3966803	-1.757630	60	SEMA6A SASH1 RAB3C ASAP1 ZNF365 GPA33 LIN7C DSE CRIM1 KREMEN1 C2orf69 PRPH2 CALM1 CCDC85A PKIA SBF2 UTP3 GSTM5 INO80 PDE4A GSPT1 SPOPL RAB2A	down	*
MIR148B_3P	0.0000003	0.0000494	0.6749629	-0.3084007	-1.746572	296	EPAS1 PNPLA6 FOXF1 TEK OSBPL11 SECISBP2L LIPA SIK1 DDX6 QKI GPCPD1 ZCCHC2 MTMR10 S1PR1 ARL8B OTUD4 EOGT TXNIP HECW2 ADAM17 ITGA5 KLF6 ITSN2 UBE2D3 RAB14 GPM6A AGO4 NRARP KLF4 LEPROTL1 ROCK1 MAFG EPM2A MPL ITPK1 CADM1 EPS15 DUSP1 PIK3C2A CUL5 PEAK1 PRICKLE2 PDE1C TANC1 NCOA1 TGFB2 SNN TMEM9B ADCY2 VPS37A PHACTR2 MTMR14 MITF BMP3 CNTN4 ATP11A MTMR9 ZNF804A FAM43A RC3H1 HOMER1 TRAK2 GPRC5A CASZ1 WDFY4 AGFG1 ITGA9 PHF3 KIAA0232 BAZ2B SBF2 SKIDA1 MMP15 ATXN1 NPTN ADAMTS15 LTBP1 PLAA CLCN6 ADAM10 DOCK6 MIER1 INO80 EPN2 RTN4 CYB5R4 MAP3K4 ING2 RASSF8 RNF38 MMD CAMSAP2 CNTNAP3B LDLR FEZ2 USP48 ZFYVE26 STARD13 CDC14A CFL2 CDKN1B TGOLN2 EYA3 NOG EFNB2 YWHAB SRSF11 SPTY2D1 WDR47 ARHGEF12 ATP8A1 ATP2B4	down	***
NPAT_TARGET_GENES	0.0000252	0.0010591	0.5756103	0.3785738	1.734835	196	FAM24B ZNF12 PAGR1 THOC3 ANKRD24 SAYSD1 YEATS4 GPI CKLF-CMTM1 MIS18A LRRC27 SPPL2B FAM220A RANBP1 CEP250 CISD1 KIF3B POLA2 LARS2 ENTPD6 SLC2A11 TRMT2A SRRM5 CKLF CBX5 CDK12 GNB1L ATP6V0E2-AS1 PHF12 SEC61G ANKRD26 TMEM79 FADD LIPT2 SMG5 NDUFA11 ATP6V0E2 DNAJA3 MAN1B1 LONP1 JMJD4 PDRG1 CGREF1 CDC7 KDM3A FAM71E1 TIMM13 NPRL3 HMGB3P22 PPP6R1 ZNF248 LSM7 SNAP47 RPP38 MST1P2 MCRS1 SMARCA4 TMEM141 PRPF31 AP001372.2 N6AMT1 NDUFA8 RPRD2 SNORA14B VDAC3 SIRT6 RANBP3 NCAPD3 TK2 NUP93 FAM222B MOK VPS26B RPL36 HINT1 MRPL45P2 ARMC6 EHMT1 XRCC5 SUGP2 PRKAB2 POLD3 COPS7A ZNF473 HNRNPA1 VRK3 GTF3A NVL DAGLB BLOC1S4 EMC10 ZBTB17 TOLLIP-AS1 FUT8 MLST8 VMAC CHCHD4 C10orf88	up	**
MIR4651	0.0001352	0.0039660	0.5188481	0.3885068	1.732969	159	ONECUT2 ENTPD2 MEX3A PCDHGA10 CPLX2 FAM177B PCDHGA9 PCDHGA5 PCDHGA7 ASIC1 PCDHGA1 PCDHGB3 RGS6 GRIN2A VSTM2L EFNA5 PCDHGA11 PCDHGA8 C9orf116 PCDHGA12 MAP3K13 PCDHGB7 PCDHGA3 WDR66 EGFR SLC9A3R1 MSI1 CYP2W1 PML TTYH3 MEOX1 SLC45A3 TTBK1 IGFBP5 SRCIN1 NAV2 ZNF584 KSR2 PCDHGA2 CCL21 NPTXR DVL3 SYNGAP1 ZBTB7B EPN1 MDGA1 RAI1 KIF21B BSN SSH3 GNG4 TFAP4 TBC1D16 MMP24 LHPP PATZ1	up	**
GTAAGAT_MIR200A	0.0029022	0.0346641	0.4317077	-0.4322972	-1.729842	39	DLC1 QKI DYRK1A UBR3 NR4A1 KLF9 PAFAH1B1 SGK1 IPO7 SP3 PCGF5 SRSF6 SP100 PURB TRMT1L KMT2E UBE3A HMGB1 RAB1A	down	*
PSMB5_TARGET_GENES	0.0000022	0.0001956	0.6272567	-0.3151716	-1.727021	221	ABHD5 TSPAN4 SNORD101 CD44 CITED2 TMEM138 SRSF7 SNORD12C CCNL1 SNHG5 ZBTB4 MALAT1 LMNA PPP1R15B EIF1 BTG2 CYB561A3 SRSF2 TOB1-AS1 MCL1 SNHG1 RHOB AHNAK RNU11 THBS1 ATF3 ID2 DUSP1 MFSD11 CALM2 AFF1 RABGGTB ZCWPW1 SLC25A3 ID4 SGK1 SRSF3 NXF1 CYCS HSPA1B JUNB DNAJA1 PPP1R15A DDX5 RNVU1-14 SLC3A2 UBB KLF2 CALM1 PXN-AS1 SRSF6 HNRNPA2B1 ZFAS1 SNORA57 TOB1 GTF2B INTS6 WDR1 ADAMTS4 IER5 RNU4ATAC HSP90AA1 TOB2 HSPA8 ACTB NABP1 EIF4A2 ATF4 PMAIP1 SLFN11 HNRNPH1 PRKG1-AS1 SERPINE1 FUS GAS5 FTL SLC38A2 ARL4D ZFP36 TUBA1A MT1E CALR POLR2L C6orf62 SNHG9 TRIM25 NDUFAF3 NFKBIZ SNORA9 KBTBD2 MEPCE EMP1 CEP95 PNP ANO10 VASN PIK3R3 TUBB3 MAT2A ADAMTS1 UBC ID1 EEF1A1	down	***
MIR935	0.0003848	0.0086498	0.4984931	-0.3546213	-1.726688	95	OSBPL11 PRKG2 LMO2 P2RY13 CLEC14A FOXJ3 ZNF365 GMEB1 TBC1D9 FOXO1 MYO1B CRIM1 SPIN1 GABARAPL2 GLUD1 ATXN1L EEA1 GFPT2 ZFAND6 KIAA0232 IRS2 LEKR1 PGGT1B HACE1 TNFAIP8 INO80 PUS10 SCAI RORA NRG1 KALRN CSNK1G3 MTSS1 CSF3 SREK1IP1 JARID2 NCOA7 ERLIN2 IREB2 ANKRD44	down	**
MIR4700_3P	0.0008500	0.0149591	0.4772708	-0.3665497	-1.720839	78	SIDT2 TAL1 FYN CAV1 SLC39A8 PAFAH1B2 NR3C1 TSHZ1 CBL LATS2 EPM2AIP1 ZNF365 FOXO1 ERP44 C9orf72 PDCD6IP TREM1 DUSP8 FBXO11 HSPA13 PCGF5 RALB	down	*
SGCGSSAAA_E2F1DP2_01	0.0001625	0.0045247	0.5188481	0.3902327	1.719821	140	GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 MCM4 MCM2 CDC25A EFNA5 C19orf57 CAND1 RANBP1 WDR62 PAQR4 AP4M1 MCM7 CLSPN RRM2 PRKDC MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 POLE2 GMNN E2F1 UNG THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2	up	**
TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D	0.0000000	0.0000057	0.7337620	-0.2956373	-1.717934	414	TRIM71 IL1A ADCY9 DPYSL2 MBOAT2 LONRF1 BAIAP2 QKI CDH13 BMPR2 SRSF7 INPP5A SFR1 NR3C1 OTUD4 ZBTB4 ATP2B1 CACNA2D2 PBX3 PICALM NLK SPIRE1 FOXP1 KLF6 RNF182 GLS MED26 SLC25A37 AKT3 ADARB1 KCNMA1 LIN7C ADO TMED5 GAPVD1 PER2 RECK UBE2B EPS15 CCSER2 SMAD7 ELMSAN1 CUL5 UNC5A BCLAF1 TBC1D4 AFF1 CRIM1 PI4K2A SNN C2orf69 MTPN PDK4 KANK1 GPBP1 CREBRF ETF1 SLC25A3 FMNL2 SLC25A25 METAP1 NSMAF PLEKHA3 HECA WSCD2 CPEB4 ETS1 CNTN4 MTMR9 FBXO11 PI4K2B MBNL2 PRKCE CREB1 RBM22 TRAK2 CGGBP1 EPC2 MEAF6 ACSL1 AGFG1 FOS SPRY4 YTHDF3 SYPL2 ZFAND6 AP1G1 PHF3 BAZ2B YTHDF2 DUSP5 CBFA2T3 LRRC32 IRS2 ATXN1 PPP3R1 NPTN GATA6 KAT2B ABI3BP PDLIM5 RLF FKBP1A CTTNBP2NL INO80 ACAP2 LRP12 EPHA4 TBC1D1 IPO5 MEX3C BRWD1 GPD1L G3BP2 PKNOX2 CUL3 TIMP3 DOCK10 FAM126B DAZAP2 FAM13B NAA15 GRB10 EIF4A2 PUM1 PURB PPP1CB RABGEF1 CBX7 KLF15 PLAG1 GREM1 CDON MB21D2 TBPL1 CLIP1 ZNF800 MAPK1 MYH10 MAMDC2 CCNK SLC38A2 EYA3 ATP1B1 CSNK1G3 PPIP5K2 PRTG C6orf62 GOLGA8B TRIM13 TSC22D2 RAD21 FNDC3A PNRC2 ATP8B5P CPNE2 ROBO2 RAB11FIP2 SIRT1 NR4A3	down	***
MIR518D_5P_MIR518F_5P_MIR520C_5P_MIR526A_5P	0.0005790	0.0114292	0.4772708	-0.3791526	-1.716929	71	SEMA6A TMEM170B JPH4 MED4 NR3C1 NCEH1 ECHDC1 LCP1 TFRC FLI1 HMGN1 PTPN21 ZSWIM6 CLK4 SLC25A33 CREBRF PLGLB1 NXPE3 CHORDC1 SAV1 ZCCHC10 EWSR1 RELL1	down	*
MIR606	0.0008466	0.0149591	0.4772708	-0.3641239	-1.711684	80	COL25A1 MBOAT2 CD44 GNPTAB PPM1D CNST CAV2 SLC7A11 SFRP1 HNRNPU UBE2D3 RUNX1T1 MAP1LC3B RBPJ DDX60L ASNSD1 WTAP SLC10A7 TCF4 ANKRD13A HFM1 POLK MBNL1 RPP30 EPHA4 BRWD1 ZDHHC21 FDX1 HNRNPC RASSF8 ACADM DNAJB5 ELP4 PRTG XRN2 RMDN1 SCAF11 SMARCA5	down	*
MIR4777_5P	0.0014797	0.0219944	0.4550599	-0.3550432	-1.706718	91	MED4 KCNN3 FBXO3 ZBTB2 SEMA6D CHMP1B KLF10 TMEM123 SPTBN1 RAB14 HIF3A FMO2 TMED5 RMDN3 PAFAH1B1 GNAI2 CREBRF SCEL CYCS NXPE3 NIPSNAP3B FOXO3 PDE12 CYGB MCUR1 PGGT1B CCR9 UBE2D1 SP100 RAD9B RORA WDFY3 ENY2 NIPSNAP3A MAP4 PHYH KLF15 NDFIP1 PIK3CG SRP14 CFLAR TTC39B KBTBD2 ZNF80 ENPEP CPPED1	down	*
MIR4671_3P	0.0000249	0.0010591	0.5756103	-0.3224108	-1.699993	182	DLC1 PPARG SECISBP2L CPEB2 DDX6 FOSL1 MTMR10 TSHZ1 TRIB1 ZBTB4 WNT2B RAP1A SRSF2 AGO4 RAB12 DGKE NPNT SOCS5 KLF7 ERP44 ARHGEF26 PNRC1 SLC6A6 PAFAH1B1 PIK3R5 MARK3 IKZF5 CNOT6L AFF3 GPBP1 CCNY TMOD1 PDIK1L APPL1 HCFC2 EPC1 FERMT2 SNX2 STX7 PSTPIP2 KBTBD8 ZNRF3 ACSL1 UBB PELI1 HIVEP2 RUNX3 NIPA2 SBF2 TOB1 SERINC3 CEP170 EPN2 RAB5A LRP12 TOB2 CYP2U1 ULK2 NPAT ING2 NR3C2 CCND3 WDFY3 VPS13D MB21D2 CLIP1	down	**
TAGAACC_MIR182	0.0030319	0.0352397	0.4317077	-0.4367031	-1.699967	35	SLC6A4 PRMT8 FLI1 DOCK9 CADM1 UBE2B CRIM1 CREM NUP153 RAB5A AMZ2P1 SRSF10 FAM126B	down	*
MIR32_5P	0.0000000	0.0000073	0.7337620	-0.2931600	-1.697884	412	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 NEDD4L BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 PRSS12 MED19 SLC7A11 GPBP1L1 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FOXN3 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 NOTCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 ZNF804A KBTBD8 MORC3 GRIA1 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 PIK3AP1 ZNF521 PHF3 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 IRS2 NFYC ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 ARPC2 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 MCOLN2 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 DUSP6 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 PIP5K1C MEF2D ZFYVE21 MTFMT ITGA6 ROBO2 DOCK5 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1	down	***
MIR1202	0.0026539	0.0322531	0.4317077	-0.3841588	-1.689799	57	OSBPL11 LRRC8C CDH5 ZBTB34 CNST LUZP1 ZNF365 LRP4 DENND6A CLIC4 SHE ZBTB43 EGLN2 CDK14 RRN3 BCL6B PSMD12 SYPL2 NR2C1 ZDHHC21 PAK2 TMEM87A	down	*
MIR570_3P	0.0000000	0.0000005	0.8140358	-0.2735946	-1.689513	635	SEMA6A SC5D COL25A1 TUBD1 TBX3 LRRC8C ATXN3 SNX10 PTPRE LIPA TMEM170B EMCN PPP4R1 SEC22C BAG4 MYADM NEDD4L QKI PAFAH1B2 KBTBD3 KCNN3 FBXO3 NR3C1 CD1C C3orf70 FAM49A DDO TMX4 STARD4 LACTB PTS TRA2B B3GNT5 CYYR1 RNF182 CAV2 CAMTA1 SLC7A11 PEX5L DACH1 SPRY2 HNRNPU GPM6A PTPN12 CWC22 TBC1D9 C14orf132 AGO3 BNIP2 PPP6R3 LIMS1 ACSL3 SLC38A11 HAUS2 PLEKHM3 ZFAND5 MYO1B ABCC4 SPAG9 MGAT4A UBE2E2 EPGN CDS2 C9orf72 ATP6V0D2 FRMD4A PLEKHB2 PIK3C2A WDR48 RAP1GDS1 KBTBD4 PAFAH1B1 BCLAF1 KPNA3 PDE1C CALM2 CRIM1 MARK3 EFR3A LIN7A LMOD3 RPS6KA2 SNX3 SERTAD2 GPBP1 SPIN1 MOB4 RBPJ SLC8A1 DCP1A PPP2CA METAP1 ELF1 FAM189A1 PDIK1L YBX1 NEK7 SNAP23 APPL1 UTRN SRSF3 ARL5B GABPA DDX17 BMP3 APBB2 AK1 HSPA13 SMU1 DDX5 MBNL2 CREB1 KBTBD8 COBLL1 RC3H1 ZBTB24 ATP13A3 TPP2 TRAK2 THSD7B OGFRL1 YWHAZ CGGBP1 ZCCHC9 ZNF407 CDK14 MORF4L1 ADNP2 CTTNBP2 YPEL2 CD164 YTHDF3 PSMD12 SRSF6 SLC35F1 XYLT1 EPHA3 PBRM1 STRN KIAA0232 PDS5B TEX14 HECW1 VAMP4 GNAI1 IRS2 TPMT CNOT7 ORC2 COL15A1 HNRNPH3 PPIG MYOCD ODF3 CLASP2 GNA13 KAT2B ADAM10 IST1 CCNH INO80D HELZ JUND ABL2 ARPC2 FKBP1A C22orf23 SCN7A MGAT2 DCTN4 RTN4 LRP12 FBXO30 DIXDC1 PTCH1 KPNA4 RBMS3 SREBF2 STAM2 HNRNPC CUL3 SCAI FNIP2 C20orf203 FAM126B PRKG1 SAMSN1 C21orf91 TMCC3 RORA FAM13C DAZAP2 GRB10 TLK1 EHD4 PURB MACROD2 ZBTB44 EIF4G2 PPP1CB DCUN1D2 ZNF326 MAP4 PSIP1	down	***
MIR608	0.0001106	0.0034752	0.5384341	0.3753168	1.686266	169	ONECUT2 ENTPD2 MEX3A PCDHGA10 CPLX2 FAM177B PCDHGA9 PCDHGA5 PCDHGA7 ASIC1 PCDHGA1 PCDHGB3 RGS6 GRIN2A VSTM2L EFNA5 PCDHGA11 PCDHGA8 C9orf116 PCDHGA12 MAP3K13 ANKRD52 PCDHGB7 PCDHGA3 WDR66 EGFR SLC9A3R1 MSI1 CYP2W1 TTYH3 MEOX1 SLC45A3 TTBK1 IGFBP5 SRCIN1 NAV2 ZNF584 KSR2 HMGXB3 PCDHGA2 CCL21 NPTXR DVL3 SEMA4G SYNGAP1 ZBTB7B EPN1 MDGA1 RAI1 KIF21B BSN GNG4 TFAP4 TBC1D16 MMP24 LHPP PATZ1	up	**
CEBPB_01	0.0000157	0.0007319	0.5756103	-0.3133981	-1.685689	204	COL25A1 ASGR1 GLIPR2 IL1B FABP4 P2RY1 MIR22HG RCOR1 PDE1B FLVCR2 P2RY13 DYRK1A TRIB1 IL23A CCNL1 EIF4A1 ITGA5 LUZP1 FOXP1 CLN5 ADRB2 TUBB6 RHOB IL10 MAP2K3 PRDM16 PTGIR SPAG9 MARVELD1 GPR85 SFTPD DUSP1 ELMSAN1 CRIM1 NCKAP5 AFF3 FOXN3 MCMBP RBM39 ETF1 VAMP3 DDX47 C2CD2 MITF RCAN1 PIK3R1 GPR3 SPRY4 PRKCG IRF5 STRN AP1G1 ZFYVE9 SKIDA1 CTNNAL1 PIM1 CSDE1 TOB1 MBNL1 BNIP3L CDC42EP3 SPIB PTCH1 CEPT1 RORA NRP2	down	***
MIR4665_5P	0.0006574	0.0126423	0.4772708	0.3920023	1.685516	120	ATP10B GRIK2 SPICE1 FOXA3 PCDHGA10 SYNPR IGF2BP3 PCDHGA9 PCDHGA5 PCDHGA7 IP6K3 UBE2Z PCDHGA1 PCDHGB3 NAALADL2 PRKCA PCDHGA11 PCDHGA8 PCDHGA12 WDHD1 PCDHGB7 PCDHGA3 CCDC148 SPINT1 ZNF32 DCLK1 C12orf75 PPM1E SDCBP2 KSR2 SSX2IP PCDHGA2 DVL3 PIGG ADAR	up	*
MIR518A_5P_MIR527	0.0000114	0.0005994	0.5933255	-0.3103144	-1.682657	216	GCOM1 ABHD5 RBMS2 NUP54 TRPC3 OTUD1 QKI SRSF7 OTUD4 PSMD5 ZEB2 HBEGF ENTPD1 RAP1A PPP1R15B PLXNA2 C1orf21 FZD4 HIPK3 TMEM123 LAMTOR3 PDE4D RHOB TLE4 AGO3 TBX4 ANKRD10 MAP1LC3B GPR85 CTBS ID2 KCTD20 JAM2 CXXC4 WASF3 NUS1 AKIRIN1 FOXN3 CREBRF DCP1A SYNPO2 SGK1 SOCS3 RAB8B PDCD6IP FYTTD1 PIK3R1 FRYL GTDC1 NAA30 RBKS FOXO3 ZFAND6 ZNF521 ISM1 TCF4 STRN DCK VAMP4 CNOT7 ATXN1 INO80D ARPC2 POLR2M ZDHHC21 KPNA4 STK4 MAFK RNF38 RORA NR3C2 ELFN1 MIER3	down	***
MIR141_3P	0.0000005	0.0000580	0.6749629	-0.2904125	-1.680372	349	SEMA6A DLC1 OSBPL11 TRHDE P2RY1 SIK1 ZBTB34 TMEM170B EGR2 HCAR2 IBA57 PAFAH1B2 NR3C1 CBL ZEB2 ERG EDEM1 B3GNT5 FOXA2 C1orf21 HIPK3 KLF6 GLS SLAIN2 FOXJ3 PLXNA4 LHX6 TNS1 TMEM41B ZEB1 ZYG11B ARRB1 DUSP3 RNFT1 ZCCHC24 PEG3 MED6 VRK2 SOCS5 MYRIP SPAG9 NPAS3 KCTD20 CCND2 ELK3 PLEK ARL4A RSL24D1 KIAA0408 CYP26B1 NCKAP5 IKZF5 TGFB2 C2orf69 CREBRF HCAR3 RAB8B PIKFYVE TMTC1 SLC14A1 MN1 APBB2 CSTA PRKCE GRB2 CREB1 TSHZ3 TTBK2 TCF4 YTHDF2 IFNAR1 IRS2 MAP3K2 ATXN1 CLASP2 GNA13 LTBP1 KIF17 PHLPP2 MBNL1 MLANA INO80D MIER1 ABL2 FKBP1A ITPRIPL2 CDC42EP3 TIAM1 TTLL7 PTCH1 IPO5 EPHA2 DAPK1 LYSMD3 RASSF8 ARPC5 FNIP2 FAM126B C21orf91 DOCK4 GSG1 SFPQ WDFY3 SPOPL MIER3 HSDL1 ARHGEF18 SUGT1 PLAG1 CHP1 CDC14A GJC1 HMGCS1 SLC19A2 MYH10 DCUN1D3 RB1CC1 PIAS2 FAM160B1 UBE3A C11orf54 KIDINS220 GABPB1 ATP8A1 DR1 WWTR1 CNTN1 SLC23A2	down	***
ZNF532_TARGET_GENES	0.0035061	0.0387024	0.4317077	0.4458224	1.680159	55	EGLN3 CDCA7 HOXB7 DZANK1 C19orf48 WASF1 RPL32P3 NSUN2 PES1 NUP205 TAF6 SRD5A1 SUDS3 NUP85 RNF187 BLCAP GOSR2 DTNB FARSB SMC2	up	*
MIR200A_3P	0.0000007	0.0000816	0.6594444	-0.2921731	-1.679694	347	SEMA6A DLC1 OSBPL11 TRHDE P2RY1 SIK1 ZBTB34 TMEM170B EGR2 HCAR2 IBA57 PAFAH1B2 NR3C1 CBL ZEB2 ERG EDEM1 B3GNT5 FOXA2 C1orf21 HIPK3 KLF6 GLS SLAIN2 FOXJ3 PLXNA4 LHX6 TNS1 TMEM41B ZEB1 ZYG11B ARRB1 DUSP3 RNFT1 ZCCHC24 PEG3 MED6 VRK2 SOCS5 MYRIP SPAG9 NPAS3 KCTD20 CCND2 ELK3 PLEK ARL4A RSL24D1 KIAA0408 CYP26B1 NCKAP5 IKZF5 TGFB2 C2orf69 CREBRF HCAR3 RAB8B PIKFYVE TMTC1 SLC14A1 MN1 APBB2 CSTA PRKCE GRB2 CREB1 TSHZ3 TTBK2 TCF4 YTHDF2 IFNAR1 IRS2 MAP3K2 ATXN1 CLASP2 GNA13 LTBP1 KIF17 PHLPP2 MBNL1 MLANA INO80D MIER1 ABL2 FKBP1A ITPRIPL2 CDC42EP3 TIAM1 TTLL7 PTCH1 IPO5 EPHA2 DAPK1 LYSMD3 RASSF8 ARPC5 FNIP2 FAM126B C21orf91 DOCK4 GSG1 SFPQ WDFY3 SPOPL MIER3 HSDL1 ARHGEF18 SUGT1 PLAG1 CHP1 CDC14A GJC1 HMGCS1 SLC19A2 MYH10 DCUN1D3 RB1CC1 PIAS2 FAM160B1 UBE3A C11orf54 KIDINS220 GABPB1 ATP8A1 DR1 WWTR1 CNTN1 SLC23A2	down	***
MIR92A_3P	0.0000000	0.0000082	0.7195128	-0.2888299	-1.676513	413	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 NEDD4L BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 PRSS12 MED19 SLC7A11 GPBP1L1 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B AFF1 NCKAP5 EFR3A AFF3 SNN LIN54 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 NOTCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 ZNF804A KBTBD8 MORC3 GRIA1 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 PIK3AP1 ZNF521 PHF3 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 IRS2 NFYC ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 ARPC2 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 MCOLN2 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 DUSP6 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 PIP5K1C MEF2D ZFYVE21 ITGA6 ROBO2 DOCK5 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1	down	***
MIR92B_3P	0.0000001	0.0000201	0.7049757	-0.2889602	-1.668548	410	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 NEDD4L BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 PRSS12 MED19 SLC7A11 GPBP1L1 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 NOTCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 ZNF804A KBTBD8 MORC3 GRIA1 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 PIK3AP1 ZNF521 PHF3 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 IRS2 NFYC ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 ARPC2 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 MCOLN2 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 DUSP6 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 PIP5K1C MEF2D ZFYVE21 ITGA6 ROBO2 DOCK5 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1	down	***
MIR487A_3P	0.0015965	0.0227925	0.4550599	-0.3469962	-1.667046	89	CLEC12A ZCCHC2 MTMR10 DYRK1A MOB1B ZEB2 BTG2 NLK PDE4D GPM6A KCNMA1 ATL3 SMAD7 LRRTM2 APPL1 MAGI2 LRCH1 SNX2 SP3 PDZD2 AGFG1 AZIN1 STXBP3 APLP2 LEKR1 ST6GAL2 KIF1B ENY2 EVI5 ATF2 CRBN	down	*
MIR4717_5P	0.0008325	0.0147903	0.4772708	-0.3565049	-1.665390	83	EPAS1 TRHDE GPR65 RAB3C FYN ERG ASAP1 SRSF2 ZEB1 ADIPOR2 PEAK1 BCLAF1 RBPJ GAS2L1 ST6GALNAC4 SERPINB6 FSD1L COL23A1 AGFG1 XYLT1 AKIRIN2 ATP6V1A PGGT1B FKBP1A KIF1B STARD13 CDC42BPB PAX5 PDE7B TES	down	*
MIR6718_5P	0.0033594	0.0376393	0.4317077	-0.3803865	-1.659840	56	EGR2 LONRF1 KCNN3 TIPARP NPR3 ABCC4 AQP4 CPT1A KPNA3 CNRIP1 SERTAD2 RYBP IPO7 MOB1A CTTNBP2 CDK17 ZRANB1 KAT2B ALDH6A1 MMD UBE2V1 ZNF800 UBA6 LHFPL2 MTSS1 ADHFE1	down	*
OCT1_03	0.0000595	0.0020959	0.5573322	-0.3197837	-1.659458	162	DAB1 MS4A7 DLC1 PPARG BDNF TMOD3 CITED2 DYRK1A ANAPC15 NFIX MCTP1 ARSB LIFR PLXNA2 FAM89A SLC7A11 UBE2D3 GLDN MOAP1 RUNX1T1 ZNF423 ATL3 RIT1 ELK3 PTCHD4 MIR17HG PIAS1 FOXN3 PPP2CA NEK7 MITF LTBP2 JPH1 DDX17 RCAN1 FBXO11 SKIL CASZ1 NDST1 FOXO3 SRSF6 TCF4 AP1G1 MBNL1 AMD1 HNRNPK FNBP4 NFKBIA CHCHD7 PRKG1 PAIP2 NRP2 TLK1 CACNA2D3 ATP6V0A1 PLAG1 ZNF385B CX3CR1 FAM53B ZNF654	down	**
MIR154_3P	0.0011027	0.0174326	0.4550599	-0.3482454	-1.654015	88	CLEC12A ZCCHC2 MTMR10 DYRK1A MOB1B ZEB2 BTG2 NLK PDE4D GPM6A KCNMA1 ATL3 SMAD7 LRRTM2 APPL1 MAGI2 LRCH1 SNX2 SP3 PDZD2 AGFG1 AZIN1 STXBP3 APLP2 LEKR1 ST6GAL2 KIF1B ENY2 EVI5 ATF2 CRBN	down	*
CAGTATT_MIR200B_MIR200C_MIR429	0.0000003	0.0000395	0.6749629	-0.2824725	-1.653611	395	DLC1 DENND5A OSBPL11 SLC16A12 GATA2 MBOAT2 CORO1C VAT1L CITED2 QKI AKAP7 ELF2 ARL8B NR3C1 OTUD4 RHOA ZEB2 SEMA6D KIAA0355 ASAP1 SERINC1 RANBP9 KLF10 LCP1 DACH1 SRSF2 ZEB1 HNRNPU GPM6A FLI1 LRP4 PPP6R3 KLF4 ZCCHC24 KLF9 MAFG CLIC4 UBQLN1 ID2 RECK UBE2B DUSP1 ADIPOR2 PPP2R5C SLC6A6 FAM76B AFF3 SIAH1 SRF USP25 RPS6KA2 KANK1 PPP2CA ADCY2 PDIK1L PHTF2 APPL1 PIKFYVE HMBOX1 GABPA SLC14A1 ETS1 MAP4K4 CNTN4 FERMT2 NDST1 IP6K1 PPM1F AGFG1 CDK17 YPEL2 YTHDF3 PKIA NAP1L5 ZFAND6 HNRNPD NUP153 PDS5B BAZ2B TSC22D1 KHDRBS1 NAB1 C16orf72 CNOT7 ATXN1 BAG6 TMEM70 TOB1 CLASP2 KAT2B GEM SESN1 RLF VASH1 MGAT2 IER5 MFAP5 UBE2D1 MEX3C BRWD1 HNRNPK SSH2 ULK2 COPS8 MTUS1 MMD NRP2 RHOT1 ZFPM2 WDFY3 BMI1 DNAJB5 EVI5 FEZ2 REEP1 PSIP1 ARHGEF17 CFL2 BHLHE41 CLIP1 HIPK1 UBA6 FHOD1 SLC38A2 FAM8A1 FBXW2 NOG EFNB2 CSNK1G3 CTDSPL2 YWHAB LMO7 C6orf62 UBE2W SGIP1 GOLGA8B TSC22D2 MATR3	down	***
MIR545_3P	0.0000011	0.0001211	0.6435518	-0.2885452	-1.648844	329	WEE1 CXCL16 DENND5A OSBPL11 SECISBP2L KCNA2 PRKG2 LYVE1 RDX RCOR1 OTUD1 STXBP6 CAV1 NEDD4L CALCRL BMPR2 PAFAH1B2 NR3C1 CBL MOB1B FAM49A CIT APOD UBR3 PEX5L ADIPOR1 EIF4E TRAF6 CRK SPTBN1 PDE4D TCF7L2 SETD3 TIPARP AGO4 ARRB1 PTAFR RRM2B PRKD3 SCAF4 SNIP1 DPH3 MGAT4A CADM1 NPAS3 NR1D2 DUSP1 RPF1 ELMSAN1 ARL4A ILDR2 PEAK1 CYP26B1 EFR3A CDKN2AIP RBPJ CREBRF KIF13A PSEN1 SEC14L1 SLC14A1 SNX29 USO1 JPH1 TMPRSS11D SHOC2 FOXN2 APBB2 SNX2 ATXN1L PIK3R1 IRF8 FAM43A RC3H1 ENTPD4 ZNRF3 CEBPZ TUBGCP3 CELF2 MAPK8 METTL14 ATAD2B INO80D SYT11 RBL2 FGF2 INTS6 LRP12 MFAP5 ARHGAP18 FBXO30 ARIH1 UBE2D1 PTCH1 G3BP2 CUL3 BCAT1 DOCK10 RNF38 SCAI KIF1B FGFR1 NRP2	down	***
SRF_Q6	0.0000124	0.0006243	0.5933255	-0.3078731	-1.648532	194	PPARG TMEM126A LRRFIP1 BDNF EGR2 CORO1C MYADM CITED2 FOSL1 CTDSP1 JPH2 KCNK3 RAP1A EMILIN2 PRELP PICALM FOXP1 KLF6 NR4A1 ZEB1 UBE2D3 CNN1 ROCK2 TNNC1 TRIM46 THBS1 NPR3 KCNMB1 ACTR3 ACTG2 MYH11 SRF CNTF TRIM55 PODN DHH JUNB RHOJ LYRM1 HERC1 RASSF2 FOS KRTCAP2 FOSB DGKG AKIRIN2 DUSP5 TGFB1I1 C16orf72 MRGPRF TAGLN MBNL1 PITPNA LDLRAD4 PDLIM5 DIXDC1 PTCH1 ACTB G3BP2 SIN3A KIF1B CNN2 RSU1 ATF4 STARD13 EGR1 CFL2 CDKN1B SVIL DCUN1D3 WNT5A LDB3 PLN MATR3 TES	down	***
CAGTGTT_MIR141_MIR200A	0.0000097	0.0005561	0.5933255	-0.2951987	-1.648445	263	SEMA6A DLC1 OSBPL11 TRHDE SIK1 QKI ELF2 PAFAH1B2 YPEL5 CBL ZEB2 RBM7 PPP1R15B C1orf21 FOXP1 TTYH2 PPP2R2A LHX6 TFRC ATP6V1B2 KIF1C STAT5A DUSP3 RNFT1 ZCCHC24 ARNTL MYRIP SPAG9 RBMS1 FRMD4A KIAA0408 CYP26B1 KPNA3 BACE1 IKZF5 SIAH1 TGFB2 FOXN3 MTPN CREBRF SLC25A3 PPP2CA PSEN1 JUN STAT4 RABGAP1 APBB2 DDX5 KLHL18 GRB2 PDZD2 CDK17 PTP4A1 YTHDF3 TSHZ3 TTBK2 STRN PDS5B YTHDF2 ATP6V1A IRS2 ATXN1 CLASP2 GATA6 PHLPP2 MBNL1 INO80D MOB3B YAF2 DIXDC1 EPHA2 GRIN3A MBD5 CUL3 ARPC5 CAMSAP2 NRP2 C2orf42 SFPQ WDFY3 YTHDC1 ARHGEF18 KALRN PLAG1 CHP1 CDC14A HIPK1 FUS MYH10 DCUN1D3 CDC42BPB ATP1B1 CSNK1G3 UBE3A MTSS1 DR1 SLC23A2 WDR26 CSF3	down	***
MIR8089	0.0010922	0.0174151	0.4550599	0.3762494	1.644041	133	EGLN3 PCDHGA10 PPP1R1B CPLX2 PCDHGA9 PCDHGA5 TTF2 TOX3 PCDHGA7 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 RANBP1 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 WDR72 CAPN12 ABCB9 CNGB1 NAA40 OSBPL7 FBXO41 KSR2 PCDHGA2 ZNF687 NRIP2 MAT1A NR6A1 PCDHGB1 ABCC10 BCL2L1 ENTPD3 ANKIB1 SLC38A7	up	*
TCCAGAG_MIR518C	0.0017740	0.0242179	0.4550599	0.3775795	1.639617	126	PCDHGA10 RPGRIP1L PCDHGA9 PCDHGA5 PCDHGA7 SDK2 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 PCDHGA12 PCDHGC5 PCDHGC4 MED12L PCDHGA4 PCDHGB7 PCDHGA3 SALL2 IQCB1 ZNF652 TNK2 DDT PCDHGA2 CHCHD3 RNF44 ZNF606 CSNK1G1 PCDH9 PCDHGB1 TWIST1 NRXN2 DNMT3A RAB15 CLUH GAD1 TCERG1 PATZ1	up	*
CCAWWNAAGG_SRF_Q4	0.0038447	0.0413386	0.4317077	-0.3657199	-1.635674	64	EGR2 CORO1C KCNK3 CSRP1 PICALM KLF6 NR4A1 TNNC1 THBS1 ACTG2 MYH11 MRVI1 SRF PODN RASSF2 FOSB TCF4 DUSP5 MRGPRF TAGLN MBNL1 PDLIM5 DIXDC1 PTCH1 ACTB EGR1 CFL2 SVIL PLN DUSP2 SREK1 NKX2-1 MYLK	down	*
MIR513B_5P	0.0000367	0.0014264	0.5573322	-0.2938660	-1.632722	234	WEE1 DLC1 TBX3 GATA2 KL RCOR1 BDNF CCDC36 VAPA TET2 SCN5A RHOA ZEB2 MED26 SPRY2 HNRNPU TCF7L2 ZYG11B EIF1B CWC22 AGO4 PRDM16 KCNMA1 PKD1L1 MED6 GAPVD1 MGAT4A GPR85 USP44 ZBTB43 SPRYD7 C2orf69 BTG1 USP25 METAP1 RYBP EBF2 NEK7 GABPA SNX2 EEA1 SNURF SLC10A7 APOL4 TMEM192 AGFG1 PKIA TRAPPC10 SRSF4 PDS5B PDE12 GNB4 CLASP2 AMD1 HNRNPK TBCEL FAM126B SYNPO2L C1orf52 GIMAP4 ARFGAP3 DNAJA2 RABGEF1 IRF2 HAT1 FAM131B ADAMTSL1 ATF2 LHFPL2 SH3GLB1 FBXW2 SV2B LRRC2 GABPB1 MAN1A1 DR1 SNRPN WWTR1 CNTN1 CCNYL1 RNGTT CCPG1 PTGS2 IMPACT BMPR1A SLC18A2 IVNS1ABP CBLL1 CASQ1 PTPN14 FEM1C TNFRSF19 PIK3R3 ERBB4 RBM27 MTDH PPP1R14C ABCE1 TMEM64	down	**
GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367	0.0000062	0.0004181	0.6105269	-0.2907952	-1.629742	266	SMAD6 GATA2 CPEB2 ATXN3 SIK1 INSIG1 ARRDC4 EGR2 BMPR2 PLEKHA1 S1PR1 P2RY13 DSCAML1 OTUD4 ZEB2 EDEM1 NFIX LATS2 ITGA5 BTG2 NLK LUZP1 REV3L GPBP1L1 MCL1 RAB14 MOAP1 PTPRO KLF4 CEBPA SOCS5 MYO1B PER2 DOCK9 TEF USP44 SMAD7 PAFAH1B1 SNN LIN54 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 PIKFYVE NECAP1 CPEB4 CNTN4 FOXN2 PTGER4 KLHL18 PRKCE CREB1 MORC3 PDZD2 TRAK2 CXCL5 GFPT2 KLF2 PIK3AP1 TGIF1 PDS5B BAZ2B CBFA2T3 TOB1 NPTN GATA6 KAT2B ADAM10 POLK PHLPP2 PITPNA CDKN1C TOB2 G3BP2 TMEM184B FNBP4 ZDHHC5 RNF38 TMEM87A LYST DNAJB9 FAM126B FAM13B KALRN ARHGEF17 LHFPL2 SLC38A2 ADAMTSL3 CD69 C6orf62 UBE2W FAM160B1 GOLGA8B SGPP1 RAD21 PIP5K1C MEF2D ROBO2 FNIP1 NR4A3 CCNC HIVEP1	down	***
MIR421	0.0004897	0.0101611	0.4772708	-0.3132577	-1.620446	144	ZC3H12C RDX TRPC3 SOX17 CALCRL QKI VAPA SEMA6D ASAP1 FAM122A CLEC1A ACSL3 RUNX1T1 KLF11 MGAT4A HOPX MBD2 ZNF706 TBC1D4 CALM2 SLC25A3 DDX60L PRDM11 DNAJC27 PHTF2 ETS1 JPH1 SP3 SLC10A7 BLOC1S6 TTBK2 ATG2B DCAF5 TESK2 ZBTB11 TLDC2 ATAD2B ARPP19 LDLRAD4 SRSF10 FAM126B RORA RSU1 CLOCK FAM8A1 KIAA2026 CTDSPL2 SGIP1 MPV17 CAPZA1 SRR FCHSD2 SREK1IP1 JARID2 ARGLU1 CASP3	down	*
SRF_Q4	0.0001846	0.0050147	0.5188481	-0.3049218	-1.619628	175	PPARG EGR2 CITED2 IER2 JPH2 KCNK3 CSRP1 EMILIN2 FOXP1 KLF6 NR4A1 MCL1 CNN1 ROCK2 TNNC1 TRIM46 YBX3 VASP THBS1 MYO1B NPR3 KCNMB1 DSTN ACTG2 MYH11 SRF TMOD1 PRDM11 SGK1 PODN DDX17 JUNB RHOJ LYRM1 HERC1 RASSF2 COL23A1 IP6K1 FOS KRTCAP2 FOSB DGKG SORT1 AKIRIN2 TGIF1 DUSP5 TGFB1I1 MRGPRF TAGLN MBNL1 PDLIM5 VGF DIXDC1 PTCH1 ACTB G3BP2 EDN1 RSU1 EGR1 ARHGEF17 CFL2 CDKN1B DUSP6 SVIL ADAMTSL1 DCUN1D3	down	**
ACTGTAG_MIR139	0.0010856	0.0174151	0.4550599	-0.3273935	-1.619421	104	HMGCR CDC42 ZEB2 UBR3 CACNA2D2 FOXP1 BTG3 SOCS2 MGAT4A FRMD4A RUFY3 FAM76B SLC25A3 PPP2CA CCNY JUN NOTCH1 CPEB4 ETS1 DHX15 FBXL16 KBTBD8 FOS AZIN1 AKIRIN2 SRSF4 TGIF1 RSBN1L ATXN1 APLP2 GPD1L PSME4 SRSF10 KPNA4 PDE4A PIEZO1 EIF4G2 JDP2 HIPK1 CTDSPL2 WDR47	down	*
MIR144_3P	0.0000008	0.0000895	0.6594444	-0.2753383	-1.619012	432	WEE1 SEMA6A TEK SGK3 HVCN1 ZC3H12C CPEB2 CDH5 KL ZBTB34 CCDC88A MED4 ST3GAL6 CALCRL ZCCHC2 MEF2A NCF2 TET2 OTUD4 TRIB1 ACER3 SEMA6D UBR3 ATP2B1 SH2B3 LIFR MAP3K8 PBX3 NLK FZD4 SPIRE1 ZBTB21 HIPK3 CAV2 SLC7A11 PPP2R2A SLAIN2 GATA3 NFE2L2 ZEB1 HNRNPU PDE4D EPB41L2 PRDM16 TSPAN12 PRKD3 ROCK1 TJP1 MED6 FBXL3 PDE8A MGAT4A PDE3B NR1D2 PNRC1 PAFAH1B1 TP53BP2 FAM76B CDKN2AIP SACM1L MOB4 CREBRF SLC25A3 PRKRA FLT1 NEK7 PIKFYVE CNTN3 ETS1 ADRA1A MTMR9 MORC3 REL ZNF597 PREX2 CGGBP1 FOS CTTNBP2 CCDC85A PPTC7 TSHZ3 XYLT1 RIN2 NIPA2 AP1G1 PDS5B BAZ2B KCTD10 MAP3K2 ATXN1 PPP3R1 APLP2 EXOC1 MYOCD GNA13 ACYP2 MBNL1 ATAD2B INO80D LDLRAD4 CEP170 SPARCL1 EPN2 IQSEC1 LRP12 TRAPPC8 ARHGAP18 DIXDC1 UBE2D1 PTCH1 MEGF9 ZDHHC21 MAP3K4 STAM2 LIMCH1 RASSF8 MAFK PTEN FAM126B RORA NRP2 NAA15 SPATA5L1 SHISA6 SPOPL PURB SLC44A5 EIF4G2 HAT1 ABI1 UBE2V1 RBMXL1 EXPH5 KCNJ6 ZNF800 CRBN ANKS1A KIAA2026 ATP1B1 CCNT2 ADAMTSL3 EBF1	down	***
MIR497_3P	0.0001116	0.0034752	0.5384341	-0.3007297	-1.618561	203	KLF13 TBX3 CPEB2 CLDND1 ZBTB34 BAIAP2 RXFP1 NR3C1 VAPA TMX4 CNST LIFR TCF7L2 FOXO1 SGTB FAM124B KLF4 PAQR5 ATG7 UBE2E2 GPR85 C9orf72 IL7R ARHGAP17 SPIN1 RBPJ PDCD6IP HECA LRCH1 GABPA MSRB3 CYCS WTAP SNX2 STX7 SP3 PCGF5 CREB1 YWHAZ ACSL1 AGPS PTP4A1 MAPK8 TMX3 CEP76 C16orf72 RELL1 SLC24A1 PPIL3 KAT2B SERINC3 MBNL1 ATAD2B SMAD2 INO80D AMD1 INTS6 SLC31A1 SPARCL1 MRPL1 RTN1 RTN4 MAP3K4 TBCEL PAK2 CNN2 EIF4G2 SCLT1	down	**
MIR1277_5P	0.0000000	0.0000004	0.8266573	-0.2615998	-1.616698	746	SMAD6 EREG GCOM1 EDNRB SGK3 KCNA2 ZC3H12C CPEB2 PRKG2 P2RY1 RDX NUP54 DPYSL2 PTPRE ST6GALNAC3 BMP2 KL BDNF PLEKHF2 MYADM NEDD4L QKI VAMP2 MEF2A RXFP1 KCNN3 NR3C1 TGFBR3 DSCAML1 TET2 MOB1B PILRA TEX2 ZEB2 DNAJB14 TXNIP NUMB KCNAB1 BRINP3 CD36 ANXA1 SSTR1 HBEGF SBDS TACC1 FOXA2 LIFR RAP1A PPP1R15B CHMP1B PLXNA2 SWT1 EMILIN2 BTG2 ZDHHC2 MAP3K8 ANXA5 NLK CSGALNACT2 KLF6 CAMTA1 SLC7A11 DACH1 FOXJ3 NR4A1 RGCC TRAF6 SPRY2 TFEC SRGN GPM6A KDSR CPED1 ROCK2 SNAI1 TLE4 TBX4 ZSWIM6 PEG3 RRM2B VASP ADAMTS9 GAPVD1 RIT1 CDS2 C9orf72 RECK CCND2 ACTR3 EPS15 CCSER2 DUSP1 PIK3C2A ELK3 SMAD7 BRF2 LYAR EXOSC8 TBX5 TM9SF2 SPRYD7 AFF1 NCKAP5 EFR3A KREMEN1 LIN7A AFF3 NCOA1 FAM102B SLC25A3 FMNL2 HESX1 PRDM11 PDIK1L VPS37A SYNPO2 PHTF2 KIF13A PHACTR2 PIKFYVE UTRN NECAP1 SERPINB8 TMTC1 ARL5B MITF GABPA ETS1 PDE5A MSRB3 FOXN2 DUSP8 SKIL ENPP4 FBXL16 ACKR3 SMU1 PCGF5 HERC1 ZNF804A IDS CREB1 COBLL1 RC3H1 SNX1 FSD1L DOCK8 HOMER1 ZNRF3 SUCNR1 CXCL5 PREX2 DENND4A BLOC1S6 SLC25A24 PELI1 NECAB1 NAPG FOSB RIN2 ZNF521 UBXN2A SAV1 TMX3 TCF4 STRN NR2C1 ZBTB1 TGIF1 RSBN1L TEC ZBTB11 CNOT7 HBP1 CNTNAP1 PLSCR4 THAP9 ADPGK TOB1 NPTN RIMKLB CSNK2A2 KAT2B SERINC3 CCNH INO80D HACE1 GEM LDLRAD4 INTS6 NEK1 ABL2 FKBP1A SF1 OPN3 CALHM2 SETDB2 CDC42EP3 MFAP5 EPHA4 SIK3 USH2A MEX3C POLR2M NUP98 EPHA2 SCPEP1 CREBBP PARVA DAPK1 STAM2 NEK3 LYSMD3 CUL3 RASSF8 TTC28 ZDHHC5 SCAI PTEN TNFSF9 MMD SAMSN1 C21orf91 FGFR1 RORA FAM13C DAZAP2 LDLR RHOT1 WDFY3 EVI5 ZBTB44 CSF2 STARD13 SPSB1 PLAG1 CDON SERPINE1 SVIL UBA6 CLOCK RB1CC1 SLC38A2 KIAA2026 ALG2 EXOC8 HP1BP3 ZFP36 PLXDC2 EFNB2 BBS7 PIGK ADAMTSL3 DNAJB4 CTDSPL2 PPIP5K2	down	***
E2F1_Q6	0.0003173	0.0074927	0.4984931	0.3525242	1.615295	198	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 ORC1 C19orf57 MCM8 CAND1 EPHB1 CDT1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 CACNA1G MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2	up	**
MIR6804_3P	0.0024576	0.0307092	0.4317077	-0.3428788	-1.609711	78	DNAH17 PPP4R1 MOB1B EDEM1 CACNA2D2 SDE2 REV3L PPP3CC LDHAL6A PTPN12 SCP2 SOCS2 PDE8A C9orf72 MBD2 NCOA1 CCDC3 ETS1 MAP4K4 ATXN1L KLHL18 PRKCE YWHAZ ADNP2 TSHZ3 CCP110	down	*
MIR3120_3P	0.0000065	0.0004277	0.6105269	-0.2832629	-1.609483	297	WEE1 GCSAML SECISBP2L ZC3H12C C18orf32 OTUD1 PPP4R1 NEDD4L PRKAR1A MEF2A NR3C1 CYP4Z1 VAPA SPG21 ASAH1 NLK PEX5L EIF4E SRSF2 EPM2AIP1 TCF7L2 RAB14 SLC7A2 TLE4 SORBS1 PPM1K FBXL3 SCAF4 SPAG9 DPH3 RBMS1 ZBTB43 ELMSAN1 ADIPOR2 PEAK1 ZNF706 PDE1C AFF1 EFR3A TGFB2 TMEM9B CREBRF ETF1 GZF1 KIF13A EBAG9 PLEKHA3 SRSF3 SNX29 JPH1 FOXN2 EPC1 MTMR9 APBB2 SKIL IDS FAM43A ATL2 DOCK8 HOMER1 OGFRL1 CEBPZ CELF2 RRAS MAPK8 DAGLA AKIRIN2 PHF3 DPM1 PDE4B MBNL1 ATAD2B RBL2 ACAP2 CXCR4 FBXO30 ARIH1 IPO5 MEX3C G3BP2 SSH2 NPAT CUL3 RAB2B DOCK10 ARPC5 SCAI PAK2 KIF1B ZFPM2 EID1 ELFN1 SLFN11 EPG5 PLAG1 TBPL1 FKBP1B	down	***
MIR8084	0.0000661	0.0022844	0.5384341	-0.3001980	-1.607574	197	MGAT3 FOXF1 ABHD5 DLC1 OSBPL1A TRPC3 BAG4 QKI WBP4 TET2 SCN5A ZEB2 DNAJB14 PTS TRA2B RAP1A HIPK3 AKT3 ZEB1 GPM6A PTPN12 MSR1 PTPN21 SETD9 RECK DUSP1 ELK3 RSL24D1 LIN7A ZNF330 MOB4 FMNL2 JUN NOTCH1 HMBOX1 SLC14A1 ATP11A OSTM1 FOXN2 PI4K2B FSD1L SLC10A7 OGFRL1 EPC2 SPRY4 CDK17 PSMD12 SRSF6 SLC35F1 CCDC152 PDS5B SLC24A1 ACYP2 PDE4B CTTNBP2NL XKR8 ING2 SCAI B3GNT2 CECR2 DNAJB9 FAM126B MMD RORA FAM13C UBE2V1 CFL2 ATP11B NR4A2 BDKRB2 PRTG IL5 EP300 CRIPT MAP3K1 NR5A2 NKD1 RAB11FIP2 SIRT1	down	**
GCATTTG_MIR105	0.0003345	0.0077508	0.4984931	-0.3096326	-1.607258	146	PDE1B NEDD4L GPCPD1 TEX2 TRA2B BMP1 FOXJ3 CRK TIPARP DENND6A ITM2B COQ10B TJP1 SOCS5 SNIP1 GPR85 CXXC4 PRICKLE2 TM9SF2 KIAA0408 SMNDC1 COPS4 NCOA1 LIN54 MYLIP RYBP GABARAPL2 CCDC3 CELF1 SP3 CELF2 CDK14 YTHDF3 AKIRIN2 MAP3K2 PPP3R1 PCCA PRDM8 SLC31A1 EPHA4 HNRNPK KPNA4 COPS8 FAM126B RAB2A MIER3 EIF4G2 KALRN CDKN1B DCUN1D3 CMPK1 RB1CC1	down	**
MIR22_3P	0.0009354	0.0155805	0.4772708	-0.3210652	-1.606616	115	RCOR1 PRPF38A TET2 KCNAB1 WWC2 PPP1R15B MTF1 KLF6 AKT3 MTHFR EPB41L2 ARRB1 PPM1K LIN7C CLIC4 FAM49B NPAS3 KIRREL3 NUS1 BTG1 PRCP CD80 PDIK1L MED28 INPP5B RASSF10 EPC1 CREB1 HOMER1 SNRK DAGLA ZFYVE9 MTMR2 ANKRD13A RGS2 SESN1 LRP12 NLRP3	down	*
E2F4DP1_01	0.0004600	0.0098627	0.4984931	0.3502331	1.604961	196	ONECUT1 GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 SEZ6 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 LIG1 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 SASS6 MDGA1 OLFML3 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2	up	**
MIR4418	0.0016523	0.0230023	0.4550599	-0.3205258	-1.603983	111	RTKN2 GFOD1 CORO1C CHRNE PICALM CAMTA1 GPM6A EIF1B DENND6A NES ZNF423 ZFAND5 MGAT4A GPR85 CCSER2 MPC1 AFF3 BTG1 SERTAD2 MED28 PPM1F AGFG1 KIAA0232 GALC ATAD2B INO80D FGF2 ATP9B G3BP2 FAM126B RHOT1 EHD4 SPOPL GPALPP1 PSIP1 CDC14A SLC25A38 RAB37 SLC38A2	down	*
PR_01	0.0021419	0.0281387	0.4317077	-0.3202990	-1.602415	109	CD52 GREB1 TIE1 WNT4 BDNF VAMP2 MTMR10 ELMO1 BRINP3 CD36 TNIP3 RANBP9 SRGN SLC7A8 GSDMA CEP57 DSTN FAM76B NCKAP5 TECTA SENP3 RWDD1 FAM189A2 ETS1 JPH1 SKIL GRB2 CASZ1 MBP KHDRBS1 JMJD1C RNF38 CHCHD7 DNAJA2 EPG5 PLAG1 ADAMTSL1 RAB37 CD109 KCNJ1 ZNF654	down	*
ACTGAAA_MIR30A3P_MIR30E3P	0.0001823	0.0050025	0.5188481	-0.3049749	-1.601329	168	EPAS1 OSBPL11 CAV1 QKI VAMP2 YPEL5 NR3C1 CBL FRAT1 FAM49A ZEB2 DNAJB14 EIF1 ZBTB21 FOXP1 FOXJ3 SFRP1 NRARP RUNX1T1 ZFAND5 STX3 ELK3 LIN7A SIAH1 SLC25A33 CDC40 DNAJC27 LRRTM2 RNF141 DUSP8 SP3 CELF2 PBRM1 AP1G1 KIAA0232 SRSF4 ZFYVE9 CDC37L1 TSPAN14 ATXN1 KCNA3 TOB1 ACYP2 TCF7L1 ARPP19 POLR2M CREBBP SRSF10 ISCU PTEN CYTH1 DLST PAIP2 FAM13B MACROD2 PSIP1 EGR1 RBMXL1 SH3GLB1 EYA3 CSNK1G3 DNAJB4 TSC22D2 ZNF22 EP300 MEF2D	down	**
MIR1271_5P	0.0000096	0.0005561	0.5933255	-0.2774227	-1.601065	323	SLC24A4 AJAP1 EPAS1 COL25A1 NOVA2 SLC12A6 ATXN3 RAB3C ST6GALNAC3 RUNDC3B TMEM170B PTPMT1 CAV1 CORO1C VAT1L QKI CTDSP1 PRKAR1A ERG EDEM1 SLC44A2 HBEGF CACNA2D2 RAPGEF4 EIF5 LCP1 CLN5 SLAIN2 PPP3CA ZEB1 TCF7L2 TAPT1 MAP2K3 AGO4 PRDM16 FOXO1 KIAA0513 TRIM46 ZFAND5 SLC7A8 STK17B MYRIP FAM49B DOCK9 PTGER3 RNF139 PIK3C2A OXSR1 PAFAH1B1 NUS1 LRRC3 TLL1 CNOT6L TOPORS MCMBP SPIN1 VAMP3 NEK7 APPL1 RAB8B MITF VAT1 SH3BP5 C20orf194 PCGF5 PRKCE GRB2 FAM43A STX5 RALB PPM1F MORF4L1 CD164 PTP4A1 FOXO3 EPHA3 SORT1 AZIN1 ABHD13 FEM1B CBFA2T3 MAP3K2 RELL1 ATXN1 PPP3R1 RGS2 NRN1 ARPP19	down	***
MIR4667_5P	0.0018856	0.0254893	0.4550599	0.3645730	1.599753	136	EGLN3 PCDHGA10 PPP1R1B CPLX2 GPAT2 PCDHGA9 PCDHGA5 TTF2 TOX3 PCDHGA7 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 RANBP1 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 WDR72 CAPN12 ABCB9 CNGB1 NAA40 OSBPL7 FBXO41 KSR2 PCDHGA2 ZNF687 NRIP2 MAT1A NR6A1 PCDHGB1 ABCC10 BCL2L1 ENTPD3 ANKIB1 SLC38A7	up	*
MIR101_3P	0.0000015	0.0001522	0.6435518	-0.2741052	-1.599325	394	AJAP1 SEMA3G SGK3 TAL1 HVCN1 CPEB2 EMP2 CDH5 ZBTB34 CALCRL ZCCHC2 CIR1 KCNN3 TGFBR3 TET2 OTUD4 USP47 UBR3 SH2B3 ASAP1 PLXNA2 PBX3 RANBP9 NLK FZD4 REV3L SPIRE1 ZBTB21 HIPK3 KLF6 CAMTA1 SLC7A11 PPP2R2A ADRB1 SLAIN2 NFE2L2 AKT3 ZEB1 PDE4D NPNT ZSWIM6 PRKD3 TJP1 CEBPA SOCS2 SOCS5 ZNF24 FMNL3 SSH1 MGAT4A COTL1 NR1D2 GPR85 C9orf72 PNRC1 CXXC4 DUSP1 PAFAH1B1 DEGS1 ZDHHC20 SACM1L ARHGAP17 MOB4 CREBRF SLC25A3 SGK1 PHACTR2 NEK7 MAGI2 PIKFYVE CNTN3 MITF NOTCH1 TBC1D12 ATXN1L PRKCE FRYL KBTBD8 MORC3 FOS CTTNBP2 KLF2 PPTC7 TSHZ3 RIN2 ING3 AP1G1 PDS5B MTMR2 CD86 TBRG1 ATXN1 APLP2 MBNL1 ATAD2B INO80D ARAP2 OPN3 EPN2 IQSEC1 RAB5A ARHGAP18 UBE2D1 PTCH1 ZDHHC21 MAP3K4 CUL3 PDE4A RNF38 RORA NAA15 C1orf52 SHISA6 PURB ENY2 EVI5 PIEZO1 DMXL2 JDP2 KCNJ6 ZNF385B ATP11B SLC19A2 MAPK1 ANKS1A NDFIP1 ATP1B1 CCNT2 ADAMTSL3 PPFIA1 CHAC2 UTS2B GABPB1 DR1 PIP5K1C FNDC3A SMARCA5 RNF111 KLHDC1 WWTR1 RAB1A ROBO2	down	***
MIR12133	0.0000116	0.0005994	0.5933255	-0.2773442	-1.596401	320	SLC24A4 AJAP1 EPAS1 COL25A1 NOVA2 SLC12A6 ATXN3 RAB3C ST6GALNAC3 RUNDC3B TMEM170B PTPMT1 CAV1 CORO1C VAT1L QKI CTDSP1 PRKAR1A ERG EDEM1 SLC44A2 HBEGF CACNA2D2 RAPGEF4 EIF5 LCP1 CLN5 SLAIN2 PPP3CA ZEB1 TCF7L2 TAPT1 MAP2K3 AGO4 PRDM16 FOXO1 KIAA0513 TRIM46 ZFAND5 SLC7A8 STK17B MYRIP FAM49B DOCK9 PTGER3 RNF139 PIK3C2A OXSR1 PAFAH1B1 NUS1 LRRC3 CNOT6L TOPORS MCMBP SPIN1 VAMP3 NEK7 APPL1 RAB8B MITF VAT1 SH3BP5 C20orf194 PCGF5 PRKCE GRB2 FAM43A STX5 RALB PPM1F MORF4L1 CD164 PTP4A1 FOXO3 EPHA3 SORT1 AZIN1 ABHD13 FEM1B CBFA2T3 MAP3K2 RELL1 ATXN1 PPP3R1 RGS2 NRN1 ARPP19	down	***
E2F_Q6_01	0.0005846	0.0114800	0.4772708	0.3484650	1.596280	195	GRIA4 CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A ORC1 XPO5 EPHB1 RANBP1 CASP2 MELK PAQR4 RND2 AP4M1 MAP3K13 CACNA1G MCM7 RRM2 PRKDC MCM3 LIG1 TOPBP1 KLHL35 MSI1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CNPY2 MEA1 CBX5 POLE2 GMNN E2F1 UNG EZH2 TNPO2 LRRC56 KPNB1 DNMT1 ZNF687 ACBD6 FANCG INTS7 NDUFA11 CCDC151 PCSK4 ANP32E DNAJC11 POLD1 MARCKSL1 ETV4 SASS6 KLHDC3	up	*
LET_7B_3P	0.0000000	0.0000077	0.7195128	-0.2607506	-1.594500	623	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
MIR10527_5P	0.0000004	0.0000538	0.6749629	-0.2662961	-1.590346	493	SLC6A4 GCOM1 MS4A7 SECISBP2L MNDA ATXN3 RAB3C KCTD9 CCDC88A LONRF1 CALCRL QKI MTMR10 DYRK1A TET2 PPM1D ACER3 KCNAB1 SSTR1 PTPRM B3GNT5 LATS2 PKD2L2 MTF1 EIF5 PBX3 ZBTB21 FOXP1 HIPK3 KLF6 EIF4E SRSF2 EPM2AIP1 MCL1 RAB14 KDSR MAP2K3 ROCK2 TBC1D9 SCP2 LIN7C YBX3 ST3GAL2 HAUS2 ZFAND5 STK17B THBS1 CEBPA LAPTM5 CTBS CXXC4 LBH CEP57 CCND2 M6PR ZBTB43 ELMSAN1 MBD2 DSTN CLIP4 SLC6A6 PRICKLE2 AFF1 BACE1 CMTM6 C2orf69 LIN54 SNX3 KCNA5 GPBP1 SPIN1 RYBP VPS37A DDHD1 PHACTR2 EBF2 APPL1 RAB8B ZFP91 ADRA1A MN1 MSRB3 CNTN4 SHOC2 RABGAP1 SKIL PCGF5 IDS RC3H1 FSD1L SLC10A7 OGFRL1 APH1B NIPSNAP3B PXK ZNF407 CELF2 CDK14 BLOC1S6 FOS SLC25A24 ADNP2 CTTNBP2 PELI1 CDK17 PTP4A1 HIVEP2 SRSF6 TSHZ3 DGKG PKIA HNRNPD VAV3 ATG2B CCP110 TBRG1 MAP3K2 CSDE1 PPP3R1 MYOCD STON1 SBSPON ZNF267 PGGT1B ADAM10 MBNL1 ARPP19 RXRA INO80D HELZ MIER1 ZNF143 CTTNBP2NL ITPRIPL2 SFT2D1 TBC1D1 POLR2M ZDHHC21 SSH2 PARVA ACADM SCAI FAM126B FGFR1 DOCK4 NRG1 CCND3 GIMAP4 DUT WDFY3 BMI1 DMXL2 ZNF326 HAT1 ABI1 UBE2V1 EXOG CDKN1B TMEM30A HIPK1 ATF2 SLC19A2 MAPK1 CMPK1 CD109 KMT2E PLXDC2 CSNK1G3 DNAJB4 LMO7 PIAS2 SGIP1 UBE3A	down	***
GTGTTGA_MIR505	0.0022357	0.0287629	0.4317077	-0.3399244	-1.587935	83	CITED2 YPEL5 OTUD4 USP47 UBR3 ATP2B1 RANBP9 SIRPA FAM122A PDE4D UBE2D3 ARNTL GPR85 KIAA0408 GPBP1 SLC25A3 LRCH1 CELF1 DHX15 CREB1 CGGBP1 YTHDF3 TTBK2 KHDRBS1 MBNL1 EPN2	down	*
LET_7F_1_3P	0.0000000	0.0000057	0.7337620	-0.2608324	-1.587791	624	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
CTTTGTA_MIR524	0.0000030	0.0002461	0.6272567	-0.2752222	-1.587660	365	IL1A SCN4A USP12 CPEB2 PTPRE DDX6 FOSL1 QKI DYRK1A CDC42 TSHZ1 FRAT1 PDCL ZEB2 PDE2A LRRFIP2 ATP2B1 NFIX CACNA2D2 BZW1 EIF5 RANBP9 NLK FOXP1 ADIPOR1 EIF4E PPP3CA SRSF2 LHX6 NDEL1 HNRNPU TCF7L2 UBE2D3 GPM6A ZMIZ1 TLE4 SRSF5 FAM76A TJP1 SNIP1 SEC24B CEP57 ARL4A SLC6A6 HES1 ADD1 TANC1 CNRIP1 NCOA1 FOXN3 MTPN RBM39 GPBP1 PRKRA ID4 WASF2 CREM DDHD1 APPL1 NXF1 NECAP1 JUN MITF STAT4 CPEB4 ZFP91 GLUD1 CELF1 SKIL SP3 MBNL2 GTDC1 SPRY4 KRTCAP2 YPEL2 HIVEP2 SRSF6 BTBD7 EPHA3 SORT1 PPP2CB HNRNPA2B1 VAV3 ITGA9 BAZ2B SBF2 GNAI1 KHDRBS1 LRRC32 IRS2 PCDH17 CSDE1 KAT2B ADAM10 ETS2 ARPP19 JUND SESN1 INTS6 MIER1 FKBP1A MGAT2 TAB2 FBXO30 HNRNPK TMEM184B SRSF10 KPNA4 PARVA JMJD1C NAA15 IQGAP1 GSPT1 WDFY3 PUM1 SMAD4 PPP1CB KALRN MB21D2 DUSP6 ZNF106 NR4A2 HIPK1 SSB CDC42BPB KMT2E ADAMTSL3 API5 SPTY2D1 LAMTOR5 MTSS1 UBE2N TSC22D2 SERP1 ARHGEF12 ATP8A1 RNF111 NR5A2 CPNE2 DACT3 NR4A3 IRX5	down	***
ATAAGCT_MIR21	0.0015836	0.0227674	0.4550599	-0.3205752	-1.585695	104	ELF2 PLEKHA1 TGFBR2 UBR3 PPP3CA SPRY2 UBE2D3 RHOB RNFT1 PER2 RECK SMAD7 MATN2 CRIM1 CREBRF SRSF3 JPH1 FBXO11 PIK3R1 PELI1 ING3 PBRM1 EHD1 PCDH17 KCNA3 TAGAP STK40 MBNL1 OSR1 TRAPPC8 EPHA4 HNRNPK TIMP3 SKI PURB PLAG1 ZNF654 TRPM7 RNF111 ARGLU1 YOD1 NTF3 YAP1 CBX4 AGO2 FASLG CREBL2 TGFBI UBE4A GID4 PCBP1 NAA50 PDCD4 NFIB CPEB3 SOX5 FCHO2 PAN3	down	*
E4F1_Q6	0.0000896	0.0028824	0.5384341	-0.2869550	-1.585514	235	ZMYND15 CXCL16 SECISBP2L KCNA2 RBMS2 SIK1 EGR2 CALCRL CRY2 NR3C1 NEDD9 TRIB1 ZEB2 ZBTB4 EIF4A1 EIF1 C1orf21 ZBTB21 PPP2R2A TOR1AIP1 NR4A1 SLC25A37 SRGN CCNI ZADH2 ZNF24 DPH3 C1QTNF7 KIRREL3 DUSP1 WDR48 SH2D2A PAFAH1B1 CALM2 MAFF FAM76B AKIRIN1 LMBRD1 RAB6A SACM1L NINJ1 GPBP1 ETF1 SLC25A25 DNAJC27 CD160 PPP6C OXNAD1 EPC1 PPP1R15A CREB1 CDK2AP2 STX5 LETM2 MCAM GPR3 PTP4A1 PSMD12 FOSB KAT8 AZIN1 HNRNPA2B1 ATP6V0C LTBP1 GEM NEK1 TNFAIP8 SLC31A1 SEC63 OSR1	down	**
LET_7A_3P	0.0000000	0.0000103	0.7195128	-0.2591992	-1.578364	626	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
MIR98_3P	0.0000001	0.0000209	0.7049757	-0.2580841	-1.578281	628	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
GTTATAT_MIR410	0.0039229	0.0417332	0.4070179	-0.3455983	-1.577041	72	RDX DPYSL2 CITED2 QKI NR3C1 MOB1B NUMB DACH1 DOCK9 SMAD7 MYLIP FMNL2 RAB8B CPEB4 ETS1 SP3 IP6K1 BAZ2B ANKRD12 MACF1 ADAM10 YAF2	down	*
MIR374C_5P	0.0000073	0.0004667	0.6105269	-0.2724933	-1.576689	349	WEE1 C18orf32 SLC16A4 TMOD3 SRSF7 HMGCR ACER3 HEG1 CLCF1 MCTP1 PCYOX1 ABCG2 CYYR1 PBX3 ZNF503 FZD4 HIPK3 GPBP1L1 DACH1 ZEB1 TCF7L2 EPB41L2 EIF1B CDADC1 TLE4 SRSF5 ZCCHC24 FMO2 ZFAND5 SOCS2 FBXL3 SYCP2L CLIC4 DOCK9 UBE2E2 GPR85 TADA2B PNRC1 FRMD4A CAPZA2 FAM76B ADD1 EFR3A CNOT6L NCOA1 SIAH1 C2orf69 SRF KANK1 MOB4 CREBRF WASF2 PHTF2 DCTN6 MAGI2 MITF SNX29 C11orf58 RABGAP1 CSTA FERMT2 ATXN1L MBNL2 ATL2 FSD1L ATP13A3 CGGBP1 GAS2L3 AGFG1 CDK17 PTP4A1 CCDC85A TRAPPC10 ZNF521 TMX3 STRN ABHD13 NAB1 LRRC32 C8orf37 EXOC1 TOB1 MACF1 ADAM10 ARPP19 INO80D RBL2 MOB3B PDLIM5 RTN1 FBXO30 TOB2 IPO5 FNBP4 ING2 GTF2F2 SCAI RORA FAM13C NRG1 RNF13 RAB2A KLC1 MAP4 UBAP1 KALRN EGR1 UBXN8 CHIC2 UBA6 SSB ITGB1 CCNK PIGK CTDSPL2 EBF1	down	***
YAATNRNNNYNATT_UNKNOWN	0.0039229	0.0417332	0.4070179	-0.3454778	-1.576492	72	SLC24A4 BDNF CDH13 ERG NFIX IFNK LHX6 ZNF423 RBMS1 NPAS3 CCSER2 IKZF5 FOXN3 PDHX CREM MN1 DDX17 CELF2 TGIF1 ELF5 ZDHHC21 MTUS1	down	*
TTGCACT_MIR130A_MIR301_MIR130B	0.0000033	0.0002673	0.6272567	-0.2752481	-1.575241	342	WEE1 EREG SASH1 KLF13 PPARG DPYSL2 SIK1 CCDC88A DDX6 LONRF1 QKI AKAP7 GPCPD1 BMPR2 S1PR1 OTUD4 TGFBR2 ZEB2 ZBTB4 PTPRM HECW2 RAPGEF4 WNT2B MTF1 CAMTA1 PEX5L NDEL1 ATP6V1B2 LRP4 AGO4 NRARP NPNT PPP6R3 PRKD3 TPP1 SOCS5 SNIP1 ITPK1 M6PR EPS15 ELK3 N4BP1 PAFAH1B1 CALM2 NRBF2 NCOA1 BTG1 ADCY2 VPS37A PHACTR2 APPL1 HECA CPEB4 ZFP91 ATP11A SNX2 KBTBD8 NAA30 EPC2 ACSL1 AGFG1 PELI1 PTP4A1 HIVEP2 RUNX3 BTBD7 TIMP2 AP1G1 PHF3 TESK2 ZFYVE9 YTHDF2 SKIDA1 CNOT7 ATXN1 HBP1 ANKRD12 NPTN PLAA MBNL1 RXRA LDLRAD4 MIER1 WDR1 INO80 CEP170 RTN1 CHMP3 RAB5A UBE2D1 BRWD1 G3BP2 ULK2 NPAT CUL3 KIT RNF38 LDLR NRP2 NR3C2 RHOT1 ZFPM2 WDFY3 SPOPL MIER3 USP48 ZFYVE26 MAP4 STARD13 MB21D2 BHLHE41 CLIP1 ZNF800 LNPEP CLOCK CMPK1 FAM53B EFNB2 CD69 SPTY2D1 IER3IP1 WDR47	down	***
MIR4650_3P	0.0019766	0.0264111	0.4317077	-0.3144469	-1.573850	112	SLC6A4 TRIM71 OLR1 GAPT LRRC8C SLC39A8 FUCA1 PDE2A CD36 UBL3 WNT2B PPP1R15B SDE2 CLEC14A AKT3 TCF7L2 ARRB1 FMO2 ZFAND5 STX3 DENND3 C1QTNF7	down	*
MIR655_3P	0.0000098	0.0005561	0.5933255	-0.2724257	-1.573640	350	WEE1 C18orf32 SLC16A4 TMOD3 SRSF7 HMGCR ACER3 HEG1 CLCF1 MCTP1 PCYOX1 ABCG2 CYYR1 PBX3 ZNF503 FZD4 HIPK3 GPBP1L1 DACH1 ZEB1 TCF7L2 EPB41L2 EIF1B CDADC1 TLE4 SRSF5 ZCCHC24 FMO2 ZFAND5 SOCS2 FBXL3 SYCP2L CLIC4 DOCK9 UBE2E2 GPR85 TADA2B PNRC1 FRMD4A CAPZA2 FAM76B ADD1 EFR3A CNOT6L NCOA1 SIAH1 C2orf69 SRF KANK1 MOB4 CREBRF WASF2 PHTF2 DCTN6 MAGI2 MITF SNX29 C11orf58 MAP4K4 RABGAP1 CSTA FERMT2 ATXN1L MBNL2 ATL2 FSD1L ATP13A3 CGGBP1 GAS2L3 AGFG1 CDK17 PTP4A1 CCDC85A TRAPPC10 ZNF521 TMX3 STRN ABHD13 NAB1 LRRC32 C8orf37 EXOC1 TOB1 MACF1 ADAM10 ARPP19 INO80D RBL2 MOB3B RTN1 FBXO30 TOB2 IPO5 FNBP4 ING2 GTF2F2 SCAI RORA FAM13C NRG1 RNF13 RAB2A KLC1 MAP4 UBAP1 KALRN EGR1 UBXN8 CHIC2 UBA6 SSB ITGB1 CCNK PIGK CTDSPL2 EBF1	down	***
MIR3934_3P	0.0043240	0.0445661	0.4070179	0.3838350	1.573338	83	MUC5B STYK1 SDK2 TMC1 NPIPB3 NAALADL2 OTOGL ANKRD36B TPCN1 TRRAP C2CD3 CCT3 HMGXB3 FAM102A IMPG2 SNX27 NFASC NPIPB4 DOK4 GAS2 LRRC20 COPS6 CYP27C1 PPP1R8 ANKIB1 DHX8 CNTN2 NCDN	up	*
MAML1_TARGET_GENES	0.0001361	0.0039660	0.5188481	-0.2885959	-1.572009	223	ARHGAP31-AS1 ZEB2-AS1 GAPT RCOR1 SH2D3C LY86 BACH1 NR3C1 NEDD9 BCL2A1 IL23A LYRM4 DNASE1L3 ZEB2 TXNIP ACOXL CD36 SBDS CYB561A3 MS4A1 TOR1AIP1 ZEB1 RNU2-6P PDE4D CD37 TLE4 P2RX5-TAX1BP3 CCL3 CCL4 CD53 PLEK HES1 RN7SL473P MOB3A MAPRE2 AFF3 SEC14L1 SFTPB CTSZ RHOG IRF8 UBAC2 REL CDK17 USP7 RUNX3 ICAM2 NAPG SLC4A5 PIK3AP1 MME TFEB GSAP TMX3 NAPSB CD1D TESK2 GPR18 SELPLG LDLRAD4 MIR155HG PUS10 SPIB TXNDC11 CD19 GTPBP8 P2RX1 IL16 CYBA JDP2 PRKCH ITGAL HES4 DRAM2 PLEKHA2 CD69 EPN2-AS1 CD79B	down	**
AAAGACA_MIR511	0.0008259	0.0147437	0.4772708	-0.3008613	-1.571042	161	ACE TXNL1 QKI ANAPC15 SEMA6D C1orf21 EMILIN2 PRELP NLK REV3L CAMTA1 AGO4 KCNMA1 ZCCHC24 KLF9 ZADH2 SOCS2 RECK MBD2 SLC6A6 ZNF706 CRIM1 EFR3A FOXN3 BTG1 CREBRF SCN4B CREM PSMA1 CELF1 MAP4K4 RHOJ ENPP4 KLHL18 ATL2 DEDD CDK14 PELI1 LMCD1 CALM1 VAV3 YTHDF2 MAP3K2 PCDH17 TOB1 SYT11 DCTN4 TRAPPC8 EPHA4 ZDHHC21 RHOT1 RAB2A ARHGEF17 DUSP6 KCNE1 FIP1L1 NR4A2 HAS2 ZNF654 CCNT2 ADAMTSL3	down	*
ATGTACA_MIR493	0.0000610	0.0021271	0.5573322	-0.2793599	-1.570145	273	IL1A TTC7B SH2D3C RASAL2 CITED2 CDH13 VAMP2 SH2B3 TM2D3 PBX3 FZD4 DACH1 MED26 ITSN2 PDE4D MCL1 ZMIZ1 PTPN12 SNAI1 TLE4 FOXO1 KCNMA1 ZFAND5 TJP1 DOCK9 PPP2R5C CUL5 ZNF706 UNC5A TBC1D4 FAM76B AFF3 NCOA1 PIAS1 MTPN BTG1 SERTAD2 ETF1 FMNL2 RYBP PIKFYVE SRSF3 TMTC1 JUN JPH1 SP3 PIK3R1 MBNL2 ZNF804A COBLL1 NDST1 CELF2 SNX9 HIVEP2 PPTC7 ZBTB11 NAB1 APLP2 PHF2 ADAM10 ACAP2 LRP12 CREBBP SSH2 KPNA4 MBD5 SIN3A RNF38 KIF1B RHOT1 WDFY3 MED17 IRF2 REEP1 VPS13D CDC14A BHLHE41 SVIL ZNF385B HMGCS1 ZNF800 HIPK1 MAPK1 ITGB1 KIAA2026 CCNT2 SRSF11 XPO7 SV2B WNT5A UNC50 UBE3A ZNF362	down	**
MIR4718	0.0029871	0.0349648	0.4317077	-0.3355871	-1.567674	83	GATA2 PLEKHA1 VAPA ZEB2 SLC3A1 TM2D3 HECW2 BTG2 HIPK3 CAMTA1 GPBP1L1 EIF4E LAMTOR3 TJP1 FAM49B ZBTB43 MBD2 ARHGEF10 RGS13 KLB HIVEP2 MMP15 NPTN SESN1 MGAT2 TIAM1 SIK3 MEGF9	down	*
E2F1_Q4_01	0.0016057	0.0227925	0.4550599	0.3442022	1.566946	189	CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A MCM8 EPHB1 RANBP1 WDR62 CASP2 MELK PAQR4 AP4M1 NUP155 POLA2 MCM7 PRKDC MCM3 TOPBP1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 TNPO2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 FANCG INTS7 NDUFA11 DHX40 DNAJC11 RHD KDM3A SASS6 PPP1R8 HMGA1 PELO MCM6 SRSF1 GINS3 OVOL2 STK35 ATAD2 EIF3K PATZ1	up	*
MIR6507_5P	0.0000744	0.0024777	0.5384341	-0.2805727	-1.566802	268	ZNF366 SGK3 CD55 QKI BMPR2 IDI1 OTUD4 STARD4 DNAJC3 PTPRM SLC36A4 ABCG2 CSGALNACT2 PPP2R2A SLAIN2 HIPK4 MYCT1 RHOB ROCK2 ITPRIP PTPRO LIN7C TSPAN12 KLF9 ROCK1 ZFAND5 DRAM1 ZADH2 GAPVD1 DOCK9 PDE3B NR1D2 GPR85 PAPSS1 ID2 CLK4 KIAA0408 PRDM5 SPRYD7 AKIRIN1 NCOA1 LACC1 CDC40 KIF13A NEK7 APPL1 PODN CNTN3 ARL5B ADRA1A PDE5A OSBPL9 C11orf58 APBB2 PCGF5 TUBGCP3 GRIK1 MEAF6 PPM1F ACSL1 MOB1A HIVEP2 MSMO1 ZBTB1 CCP110 MAP3K2 ORC2 ACYP2 MICU3 PGGT1B ARPP19 FGF2 EPB41L5 CDC42EP3 VPS4B ARIH1 USH2A ZDHHC21 ULK2 METTL7A CEPT1 SCAI PAK2 FOXJ2 PTEN FAM126B PRKG1 CAMSAP2	down	**
MIR12129	0.0022040	0.0287139	0.4317077	-0.3101996	-1.566252	121	KCNA2 BDNF UBR3 ARSB RAP1A CYYR1 NR4A1 TIPARP AMOTL1 SDCBP KLF9 SEC24B MGAT4A DOCK9 RBMS1 CXXC4 CCSER2 RNF139 PPP2R5C HSDL2 FAM102B LIN54 BTG1 KCTD12 SKIL PIK3R1 FAM43A YPEL2 EPHA3 KHDRBS1 MAP3K2 PCDH17 MIER1 SEC63 NUP98 ZDHHC21 SSH2 SIN3A RHOT1 MIER3 KALRN KCNJ6 ICOS RAB37 SLC38A2 KIAA2026 KMT2E CCNT2 KLHDC1 NKTR SIRT1 FNIP1 JARID2 KBTBD2 SETBP1 NSMCE4A PHIP	down	*
MIR582_3P	0.0037917	0.0411241	0.4317077	-0.3394158	-1.565776	75	GCOM1 U2AF1 LONRF1 RHOA SLC44A2 HERC3 ACTR3 ZBTB43 N4BP2L1 RAP1GDS1 PEAK1 HTRA4 NRBF2 NEK7 PPA2 MAP4K4 FERMT2 SKIL PALMD AZIN1 UBXN2A AKIRIN2 ATAD2B SCN7A DIXDC1 POLR2M	down	*
MIR1275	0.0004834	0.0101600	0.4984931	0.3365564	1.563736	226	ATP10B GRIK2 SPICE1 FOXA3 PCDHGA10 SPOCK1 ASB4 SYNPR IGF2BP3 TNNI1 PCDHGA9 PCDHGA5 PCDHGA7 IP6K3 PCDHGB2 PCDHGA6 UBE2Z PCDHGA1 PCDHGB3 NAALADL2 PCDHGB6 PCDHGB4 PRKCA GUCA1B PCDHGA11 PCDHGA8 PCDHGA12 COPG1 PCDHGC5 PCDHGC4 WDHD1 PCDHGA4 PCDHGB7 PKM PCDHGA3 CCDC148 SPINT1 SLC45A3 ZNF32 DCLK1 C12orf75 PPM1E SDCBP2 KSR2 SSX2IP HMGXB3 PCDHGA2 LAPTM4B COL1A1 NFASC DVL3 PIGG ADAR CADM4 TMTC2 SRGAP1 SPA17 PCDHGB1 SH2B1 HMGA1 FAM50B ACLY	up	*
MIR6882_3P	0.0020020	0.0265819	0.4317077	-0.3211021	-1.563479	95	DAB1 PID1 TMEM170B SEC22C OTUD4 CBL TGFBR2 HEG1 TMX4 WWC2 MTF1 FOXP1 PRSS12 AKT3 TCF7L2 TFRC PRDM16 LIN7C AFF1 KREMEN1 CREBRF ADCY2 RAPGEF1 FRYL OSM SNRK RRN3 AKIRIN2 ANKRD13A RGS2	down	*
MIR548AA_MIR548AP_3P_MIR548T_3P	0.0000014	0.0001454	0.6435518	-0.2642503	-1.558744	460	SEMA6A SASH1 SWAP70 OSBPL11 TBX3 ZC3H12C RUNDC3B TRPC3 ZBTB34 TMEM170B OTUD1 PPP4R1 CCDC88A DDX6 CITED2 CALCRL ZCCHC2 ARL8B NR3C1 VAPA AGTPBP1 EPB41L3 MOB1B HEG1 ZEB2 DNAJB14 NUMB WWC2 BMP1 UBL3 PCYOX1 LMNA C1orf21 RAB33B SERP2 ZBTB21 RNF182 DACH1 MYCT1 TIPARP TAPT1 PER3 FOXO1 HNRNPA3 FAM124B RNFT1 PRKD3 KLF11 ZFAND5 VASP FBXL3 KIF26A SSH1 CDS2 PAPSS1 TEF CCND2 ARAP3 ZBTB43 WASF3 MPC1 ZNF706 PIAS1 FOXN3 RPS6KA2 MOB4 SENP3 C2CD2 MITF GABPA DDX17 C11orf58 CYCS RABGAP1 FOXN2 AK1 WTAP MCM9 SNX2 SKIL GLIPR1 TTC14 SP3 PABPC4 DDX5 MBNL2 CREB1 COBLL1 PREX2 YWHAZ SNRK CDK14 PELI1 CDK17 MAPK8 ING3 DDHD2 TMX3 CNOT7 MAP3K2 PIM1 PPP3R1 CCR1 MACF1 KAT2B MBNL1 JUND NEK1 NBN EPN2 BRWD1 ZDHHC21 CREBBP RBMS3 TBCEL LIMCH1 RET TTC28 TIMP3 RNF38 SCAI TMEM87A PRKG1 KIF1B RORA	down	***
PEA3_Q6	0.0002375	0.0061975	0.5188481	-0.2846833	-1.557015	230	GPD1 FFAR4 TSPAN4 HHEX LPXN BDNF CTSW RTN3 NCF2 FUCA1 CBL HPS5 SYNC TXNIP MMRN2 CD5 PICALM GATA3 AKT3 SPI1 ZNF365 FLI1 GPA33 ZCCHC24 ATL3 MARVELD1 CADM1 ST7L PTPRC SELL SELP XCL2 CD53 PRF1 ARHGDIB WASF2 PDIK1L CTSS ETV3 CELF1 RHOG EPC1 IPO7 STX5 MSANTD2 CAP1 WDFY4 RUNX3 BIN2 ZRANB1 SBF2 DUSP5 MR1 IL18 CTTNBP2NL ADAMTS4 SF1 CALHM2 ELOVL1 NT5C2 SIK3 NLRP3 EPHA2 ZDHHC5 PUM1 FCRL1 GPN2 CDC14A HIPK1 FAM53B YRDC CD69 POLR2L MAP4K2 GPR137B CAPZA1 FCGR3A OMA1 CD3E RAB39A KCNAB2 NIPAL3 GTF2H1 ARHGAP30 SRRM1 EXTL2 LAYN GNL2 FERMT3 ARFGAP2 RELT TAF5 ARAP1	down	**
GTGACTT_MIR224	0.0008998	0.0153996	0.4772708	-0.3024451	-1.554466	131	CPEB2 DPYSL2 EGR2 QKI HMGCR CDC42 IL1RN CIT TRA2B PTX3 NR4A1 HNRNPU UBE2D3 KCNMA1 ITM2B ZNF423 ID3 CDK9 MAFG FAM49B UBQLN1 AFF3 ZDHHC20 FOXN3 SERTAD2 TMEM9B MYLIP CREBRF KCTD12 WTAP MBNL2 KBTBD8 CGGBP1 EPC2 FOSB AZIN1 NUP153	down	*
MIR301A_3P	0.0000321	0.0012760	0.5573322	-0.2711767	-1.553503	337	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 MCTP1 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 PXK ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	**
MIR301B_3P	0.0000321	0.0012760	0.5573322	-0.2711767	-1.553503	337	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 MCTP1 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 PXK ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	**
CEBPA_01	0.0004902	0.0101611	0.4772708	-0.2875128	-1.547213	186	TNR SMAD6 GPATCH11 CD55 SLC16A12 ARRDC4 BDNF HCAR2 RASAL2 AQP9 S1PR1 TRIB1 EIF4A1 MCTP1 CHMP1B GPBP1L1 RBM4 SIRPA ADRB2 LHX6 ZEB1 PDE4D MAP2K3 ID3 ZADH2 CADM1 UBE2E2 GPR85 FCER1G HTRA4 CRIM1 NCKAP5 FOXN3 MYO1C HCAR3 MITF NOTCH1 RHOBTB2 JPH1 FBXO11 SP3 GYPC ITGA11 RHOQ TSC22D1 SKIDA1 SLC24A1 CSDE1 TOB1 TCF7L1 MBNL1 SPIB RASSF8 COL13A1 NRP2 PPP1CB FNBP1 CFL2 CHML ZBTB8OS CLOCK RB1CC1 CD109 KMT2E CTDSPL2 CALR WNT5A NXN ANGPT2	down	*
E2F_Q4	0.0024354	0.0306974	0.4317077	0.3367035	1.546563	202	GRIA4 CDC45 GABRB3 GPAT2 CDCA7 E2F8 NABP2 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 CDT1 RANBP1 WDR62 PAQR4 AP4M1 SPTB POLA2 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 INTS7 HIRA DNAJC11 RHD POLD1 TYRO3 ATAD5 SASS6 PPP1R8 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 RAD51 ARHGAP11A KIAA0825 MXD3	up	*
E2F_Q6	0.0011476	0.0179972	0.4550599	0.3373540	1.546078	199	GRIA4 CDC45 GABRB3 GPAT2 CDCA7 E2F8 NABP2 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 CDT1 RANBP1 WDR62 PAQR4 AP4M1 SPTB POLA2 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 INTS7 HIRA DNAJC11 RHD POLD1 TYRO3 ATAD5 SASS6 PPP1R8 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 RAD51 ARHGAP11A KIAA0825 MXD3	up	*
MIR4276	0.0001607	0.0045076	0.5188481	-0.2843525	-1.542869	220	EPAS1 KMO SGK3 OSBPL11 TRHDE SOWAHC TBX3 IL1B GPC5 SMIM12 CLEC12B QKI TET2 EOGT FAM49A TLCD2 DENND2C ZEB2 SH2B3 RRAGC ASAP1 HECW2 CSGALNACT2 GATA3 RB1 AKT3 ITSN2 UBE2D3 PTPRO MPEG1 TSPAN12 AFAP1L1 NR1D2 SIK2 USP44 ZBTB43 CYP26B1 RASGEF1B PRDM11 VPS37A INPP5B APPL1 HECA C20orf194 CNTN4 TBC1D12 FERMT2 RC3H1 ACSL1 EMC7 KIAA0232 SBF2 TSC22D1 NAB1 IFNAR1 ADAM10 CALB1 B3GALNT1 SETDB2 USPL1 TMOD2 CAMSAP2 RORA MIS18BP1 ZFYVE26 PLAG1 CSF2RB CDC14A CDKN1B EXOC8 TBC1D23 PLXDC2 CTDSPL2	down	**
TAATAAT_MIR126	0.0004753	0.0100754	0.4984931	-0.2908408	-1.540123	173	RASAL2 VAPA TSHZ1 ZBTB2 ERG SEMA6D ATP2B1 HECW2 LDLRAD2 BZW1 GPBP1L1 DACH1 TFEC PTPN12 CLEC1A PPP6R3 DENND6A RUNX1T1 UHRF1BP1L SPAG9 PNRC1 PLEKHB2 ZMPSTE24 MPC1 STK24 FOXN3 GPBP1 HECA JPH1 PRKCE COBLL1 AP3B1 GRIK1 CELF2 TSHZ3 ING3 AZIN1 AP1G1 SKIDA1 ATP6V1A C16orf72 MAP3K2 KAT2B PRDM8 RNF138 ZNF583 KPNA4 CEPT1 EIF4A2 PURB PLAG1 GHR BHLHE41 DCUN1D3 NDFIP1 PDE7B HMGB1 MAN1A1 ARHGEF12 CUL2 FNDC3A MEF2D NR5A2 NKD1 RAB11FIP2 MAT2B NDUFAF3 LRP1 ARGLU1 SRRM1 ERLIN2	down	*
ATGCAGT_MIR217	0.0043424	0.0446318	0.4070179	-0.3189684	-1.538793	92	KCTD9 VAT1L ZCCHC2 DYRK1A PPM1D UBL3 TACC1 PAQR3 DACH1 NDEL1 MAPK8IP1 GPM6A CUL5 MTPN RBM39 FBXO11 RIN2 HNRNPA2B1 PDS5B ATP6V1A PCDH17 KCNA3 YAF2 SLC31A1 TLK2 EIF4A2 SPOPL MIER3 YTHDC1 NR4A2 MAPK1 MAMDC2 SLC38A2 KIAA2026 ATP1B1 ESCO1 TAF1D SIRT1	down	*
MIR4778_5P	0.0009192	0.0154488	0.4772708	-0.2970715	-1.537794	147	SLC6A4 AKAP5 ABHD5 SLC12A6 HMGCR SLC15A3 EOGT EPB41L3 ABCB1 SLC36A4 ABCG1 NRARP CYP4X1 SETD9 USP2 CD302 UBE2B DSTN PHTF2 HECA PIK3R1 CREB1 HOMER1 CGGBP1 CD164 ZRANB1 CCP110 SLC24A1 MACF1 ZNF267 PDE4B INO80D FBXO25 MBD5 KLLN GLUL LIMCH1 RORA ITCH CNTNAP3B SMAD4 GPALPP1 FJX1 SH3GLB1 CCNT2 EBF1 YWHAB PIAS2 MTSS1 UBE2N ANKHD1 CRIPT PTPRQ PJA2 SRRM1 KCTD18 ENPEP BICD2	down	*
ACATTCC_MIR1_MIR206	0.0000758	0.0025029	0.5384341	-0.2746454	-1.537433	274	TSPAN4 KLF13 TTC7B BDNF BAG4 CORO1C CITED2 QKI VAMP2 HMGCR CDC42 TGFBR3 CBL SEMA6D ZBTB4 TRA2B OLFML2A PICALM FOXP1 EIF4E SFRP1 ANKRD29 TFEC HNRNPU SLC7A2 CPED1 HMGN1 LIN7C CDK9 UBQLN1 TMSB4XP8 WDR48 PAFAH1B1 C2orf69 SLC25A25 PDIK1L CREM SRSF3 GAS2L1 ETS1 DDX17 DHX15 SNX2 DDX5 MSANTD2 YWHAZ CEBPZ TAGLN2 CDK14 YPEL2 HIVEP2 SLC35F1 FOSB DGKG NAP1L5 AZIN1 PBRM1 AP1G1 VAMP4 RSBN1L ATP6V1A MEIS1 ADPGK PHLPP2 JUND RNF138 PDLIM5 CTTNBP2NL SEC63 ACAP2 TMOD2 MEX3C HNRNPK TIMP3 EDN1 RNF38 MMD	down	**
MIR7162_3P	0.0008162	0.0147120	0.4772708	-0.2853304	-1.535814	192	TRIM71 ANGPT4 DLC1 KLF13 SECISBP2L RAB3C THAP2 QKI GPCPD1 EML1 TBC1D7 BMPR2 GNPTAB FAM49A SPCS3 SLC19A3 SH2B3 STARD9 FOXP1 PLXNA4 RB1 RUNX1T1 LEPROTL1 MED6 FMNL3 DPH3 RBMS1 TEF USP44 CCND2 MYH11 VEPH1 HTRA4 PRDM11 UTRN UHRF2 MTMR9 APBB2 FAM43A GCNT4 UVRAG EGLN2 PPM1F GPR3 YTHDF3 SRSF6 VAV3 PDS5B SH3RF3 ATXN1 ADAMTS15 ADAM10 ABL2 ZNF583 XKR8 CEBPD TAB2 ALDH6A1	down	*
MIR196A_3P	0.0024683	0.0307092	0.4317077	-0.3082733	-1.534953	107	EPAS1 AATK SEC22C CORO1C TEX2 SPIRE1 SLC25A37 SPTBN1 DUSP3 C9orf72 CUL5 ADD1 SEC31A SRF INO80C MED28 USO1 MSRB3 RABGAP1 FOXN2 ATL2 MSANTD2 PTP4A1 FOXO3 MAPK8 PBRM1 ATXN1 PPP3R1 ANKRD13A INO80D	down	*
MIR513A_3P_MIR513C_3P	0.0000188	0.0008193	0.5756103	-0.2636844	-1.532288	371	SLC6A4 PPARG MBOAT2 PTPRB RUNDC3B TMEM170B JPH4 BAG4 NEDD4L ELF2 RXFP1 WBP4 MOB1B EDEM1 ARHGAP29 CNST RASGRP4 ZDHHC2 RANBP9 SPIRE1 ZBTB21 SLC7A11 ZBTB8A PPP3CA LAMTOR3 ZFYVE16 UBE2D3 TMEM38B FBXO8 EFCAB14 CYBRD1 LIN7C PAQR5 SETD9 ZFAND5 PDE8A PTPRC WASF3 KLRD1 SPRYD7 NUS1 CNOT6L NCOA1 LIN54 TOPORS LACC1 SNX3 GPBP1 ELF1 RYBP PDIK1L VPS37A SAR1A KIF13A APPL1 RAB8B SERPINB8 TMTC1 ARL6IP6 CCDC50 TBC1D12 SKIL EEA1 SP3 IDS CREB1 RC3H1 FSD1L HOMER1 PREX2 YWHAZ CASZ1 ZCCHC9 RNF146 AGFG1 CDK17 PTP4A1 YTHDF3 AZIN1 PPP2CB STRN NDUFA5 JMJD6 ABHD13 TSC22D1 FEM1B TRGC1 NAB1 TPMT ADAM10 CALB1 HACE1 RNF138 TXNDC11 ALDH6A1 HNRNPK ZDHHC21 RBMS3 MAP3K4 CUL3 RASSF8 TTC28 SCAI PTEN CHCHD7 SNX15 MCOLN2 PRKG1 ITCH GSPT1 EIF4A2 HPCAL4 ZNF326 ABI1 KLF15 KALRN	down	***
MIR3666	0.0000403	0.0015343	0.5573322	-0.2662071	-1.530330	339	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 CIT TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	**
E2F1_Q3	0.0014317	0.0213671	0.4550599	0.3319278	1.529400	207	GRIK2 GRIA4 GABRB3 CDCA7 E2F8 NABP2 CDC6 E2F3 GAPDH SLITRK5 MCM2 CDC25A ORC1 C19orf57 MCM8 CAND1 EPHB1 WDR62 PAQR4 KIF15 AP4M1 SPTB CACNA1G MCM7 CLSPN RRM2 MCM3 TOPBP1 DNAJC9 DCTPP1 PKMYT1 CNOT3 CDK1 POLE2 PHF12 GMNN E2F1 EZH2 THAP8 ZNF827 DNMT1 ZNF687 ACBD6 PELP1 NDUFA11 HIRA EPHB2 PCSK4 POLD1 TYRO3 ATAD5 SASS6 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 OVOL2 STK35 ATAD2 NUP62 MSH2 YBX2 ABCF2 ARHGAP11A MXD3 E2F7 RABL6 ZNF367 NELL2 LASP1 LUC7L3 ADAMTS2 PLK4 RBL1 FBXO5 TMPO FMO4 SHMT1 ZNF524 TIPIN MTF2 SIX5 GPRC5B PAN2 KLF5 POLD3 RAVER1 STMN1 RMI2	up	*
MIR6079	0.0032895	0.0369667	0.4317077	-0.3043396	-1.528453	118	PRX ATXN3 CORO1C BMPR2 ZCCHC2 OTUD4 EPB41L3 KIAA0355 MS4A1 HIF3A HMGN1 KCNMA1 ADO MVB12B MYRIP DSTN ILDR2 PRICKLE2 VEPH1 CDKN2AIP FOXN3 SACM1L CREBRF MITF YWHAZ PTP4A1 MSMO1 MME HNRNPD TIMP2 ATP6V1A C16orf72 SCARA5 SPOCK2 ATAD2B CHURC1 RTN4	down	*
MIR122B_5P	0.0005065	0.0104411	0.4772708	-0.2878071	-1.527647	174	RAB11FIP1 P2RY1 CLDND1 THBD DDX6 FOSL1 NR3C1 PKHD1L1 UBL3 SBDS RAPGEF4 RAP1A ITGA5 EIF5 PBX3 PICALM ADRB2 ZFYVE16 ITSN2 CYBRD1 RAB12 DRAM1 CLIC4 SIK2 PIK3C2A ELMSAN1 DSTN PEAK1 MYO1C PPIL4 ID4 VPS37A NXF1 C2CD2 KCTD12 MAP4K4 APBB2 VPS26A TOM1L2 PANK2 RHOQ SPOP ZNF596 PCDH17 ATXN1	down	*
MIR300	0.0000091	0.0005408	0.5933255	-0.2606635	-1.522965	382	USP12 EMP2 GPR65 PTPRE RAB3C BDNF FYN SEC22C CORO1C HEATR5B QKI BMPR2 GTF2I P2RY13 NR3C1 VAPA PPM1D IER2 SEMA6D CLCF1 UBL3 PPP1R15B CAMTA1 PEX5L ZNF697 SLAIN2 FOXJ3 PPP3CA ATP6V1H KDSR CWC22 EFCAB14 MAP2K3 FOXO1 SGTB SORBS1 MPEG1 ACSL3 KLF4 ITM2B CADM1 AXL PNRC1 ACTR3 MATN2 GNAQ KIAA0408 PAFAH1B1 KPNA3 HES1 RABGGTB CNOT6L USP25 RBPJ CREBRF RYBP PHACTR2 PPP6C PDE5A JPH1 EPC1 ELOVL7 IPO7 FYTTD1 SKIL MBNL2 MALT1 RC3H1 REL CGGBP1 TMEM128 AGFG1 SLC25A24 PTP4A1 HIVEP2 SLC4A5 BTBD7 ZNF521 ATG2B CHRAC1 ZBTB1 PDS5B CEP76 KHDRBS1 CNOT7 HBP1 ORC2 GNB4 CRY1 GNA13 RIMKLB PHF2 ARAP2 PDLIM5 SCN7A RTN1 ARIH1 PTCH1 ULK2 MBD5 LYSMD3 NFKBIA CEPT1 SCAI B3GNT2 KIF1B RORA ITCH RHOT1 ZFPM2 EIF4A2 NUP160 RAB2A YTHDC1 ABI1 PSIP1 KALRN ZNF800 LIN52 CLOCK FUS MYH10 XPO7 TRPM7 UBE2W WNT5A WAC MTSS1 AKAP12 TES PAXBP1 ARHGAP44 ZFYVE21 NR5A2 ITGA6 ORC4 NKTR RAB11FIP2 PLCB4 EDIL3 FNIP1	down	***
E2F_Q3_01	0.0026265	0.0320240	0.4317077	0.3321112	1.521365	195	CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A MCM8 EPHB1 RANBP1 WDR62 CASP2 MELK PAQR4 AP4M1 NUP155 POLA2 MCM7 PRKDC MCM3 TOPBP1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 TNPO2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 FANCG PELP1 INTS7 NDUFA11 DHX40 DNAJC11 RHD KDM3A SASS6 PPP1R8 HMGA1 PELO MCM6 SRSF1 GINS3 OVOL2 STK35 ATAD2 EIF3K PATZ1	up	*
CREBP1_Q2	0.0002880	0.0070687	0.4984931	-0.2820060	-1.520487	207	SLC6A4 FAM167A ZMYND15 KLF13 HHEX RBMS2 SIK1 EGR2 AGPAT4 TRIB1 ZBTB21 PPP2R2A SPI1 PDE4D DIABLO TAPT1 DAAM2 PEG3 ID3 USP2 DPH3 SIK2 PNRC1 CCND2 PER1 DUSP1 WDR48 PAFAH1B1 CALM2 MAFF AKIRIN1 RAB6A KCNA5 GPBP1 SLC25A25 FLT1 CREM DNAJC27 OXNAD1 OSBPL9 RCAN1 PPP1R15A CDK2AP2 LETM2 MCAM FOS GPR3 FOSB ING3 PNPLA3 HNRNPA2B1 ZBTB11 ATP6V0C CSDE1 PPIG LTBP1 MBNL1 GEM SLC31A1 VGF OSR1 EPHA2 RET THRAP3 DLST GPR171	down	**
GTF2A2_TARGET_GENES	0.0000086	0.0005164	0.5933255	-0.2620263	-1.520466	406	SNORD101 KCTD9 RNU1-1 WDR74 RADIL BAIAP2 SRSF7 RPL23AP53 EOGT ATF7IP2 SNHG5 ZBTB4 MALAT1 EIF1 CSRP1 EIF5 REV3L KLF6 SERPINB9 SRSF2 UBE2D3 TFRC TOB1-AS1 MCL1 NBPF12 SNHG1 CCNI ADARB1 SNAI1 PPT1 PTPN21 ZSWIM6 RNU11 PLEKHM3 RNU12 CEBPA CDKN1A NKIRAS1 ATF3 VIM ID2 LBH PTGER3 DUSP1 MFSD11 CARS2 HES1 CALM2 AFF1 BTG1 MYLIP TRAF3IP2-AS1 SGK1 TULP2 SOCS3 SEC14L1 SRSF3 NXF1 SNHG8 CYCS HSPA1B JUNB DNAJA1 EPC1 PPP1R15A IFRD1 PABPC4 DDX5 SELENBP1 HOMER1 NOL7 RNVU1-14 SLC3A2 FOS UBB CALM1 PXN-AS1 SRSF6 FOSB C19orf38 AZIN1 SAV1 ZNF596 EHD1 MRPL39 AP1G1 RNU2-63P KCTD10 MIA3 DYNC1LI1 SNORA57 TOB1 RNU5D-1 RGS2 GTF2B AMD1 JUND ZNF143 EGFL7 VGF RNU5B-1 IER5 RNU4ATAC HSP90AA1 USPL1 ACTB BRWD1 PCBP1-AS1 GLUL CHCHD7 RNU5F-1 TNFSF9 SFPQ EIF4A2 ATF4 PIEZO1 PIM3 HERPUD1 EGR1 PLAG1 ZBTB8OS FUS ING1 FTL HP1BP3 ZFP36 COX20 DNAJB4 CALR HMGN2 DNAJB1 SNHG9	down	***
MIR4275	0.0039390	0.0417514	0.4070179	-0.2961954	-1.519280	130	LYVE1 LRRFIP1 PTPRB QKI UBR3 STARD4 SH2B3 COQ7 MASP1 TMEM41B UBE2D3 ZNF423 UBQLN1 LRRC40 NR1D2 USP44 CCND2 SLC6A6 KPNA3 FAM76B USP25 ARHGAP17 ELF1 NEK7 SF3B1 DNAJA1 DHX15 AP3B1 RNF24 PTP4A1 YTHDF3 CHORDC1 EPHA3 TMX3 FEM1B KHDRBS1 MAP3K2 MICU3 EPB41L5 SRSF10 TBCEL FAM126B GSPT1 RAB2A PMAIP1 EIF4G2 HNRNPH1 ZNF326 PSIP1 MB21D2	down	*
MIR4295	0.0000432	0.0016299	0.5573322	-0.2652122	-1.518781	338	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 LRP4 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	**
MIR454_3P	0.0000291	0.0012084	0.5756103	-0.2607562	-1.515272	371	WEE1 EREG DLC1 PPARG SECISBP2L CPEB2 GPR65 DPYSL2 INSIG1 TRPC3 TMEM170B FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 MCTP1 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 IKZF5 BTG1 TMEM9B CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 ZNF555 CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 PHF3 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 NPTN PLAA CLCN6 SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 CHMP3 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	**
AGCATTA_MIR155	0.0039261	0.0417332	0.4070179	-0.3015345	-1.514365	118	WEE1 SGK3 BACH1 QKI S1PR1 KCNN3 ATP2B1 NFIX PICALM CAMTA1 SPI1 UBE2D3 TLE4 SDCBP GPR85 N4BP1 RAB6A CREBRF ARL5B ETS1 CNTN4 FBXO11 SP3 YWHAZ CELF2 HIVEP2 TSHZ3 PKIA PDE12 TSPAN14 HBP1 MEIS1 TAB2 G3BP2 SSH2 BCAT1 SKI	down	*
MIR130A_3P	0.0000189	0.0008193	0.5756103	-0.2640984	-1.511431	342	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 PHF3 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	***
ZNF436_TARGET_GENES	0.0002247	0.0059050	0.5188481	0.3102796	1.511069	384	ANKRD18A FAM201A KLC3 DDX11 LAD1 DNAH2 EPN3 HBA1 ELOVL6 GALNT6 EYA2 IQCE GCNT3 SLC2A1 PLEKHA6 TTC39A SPDEF STAB2 IGFBP6 ACOT8 ZNF221 SPINT2 PLEKHA7 GRB7 HPS3 ASPHD2 LIPE-AS1 EPS8L1 POLM RFXANK AURKA SSPO GTPBP3 TMEM132A ANKRD19P MDFI KISS1R SLC4A11 ZNF226 SARS2 C2orf72 PIH1D1 AKT2 CNGB1 PKMYT1 EEFSEC FBXL19 LRRC45 CCDC136 UQCR11 BTBD2 CCDC78 PLOD2 SUPT5H CROCC BCAS4 SSUH2 EEPD1 ATIC ZSCAN25 ANKRD54 REEP6 MAP3K10 PACSIN1 TSPAN31 KXD1 PBLD SEMA4F PRR22 KCNH3 CATSPERG ARHGEF16 ATP6V0E2 DVL3 LONP1 DOK4 PCSK4 HDAC1 S100A9 MTND5P11 HID1 SPAG1 ZSWIM3 ETV4 MDGA1 RAI1 RPA1 UBXN6 FIBCD1 TFCP2L1 ABCA7 PRMT1 SRPK2 NOSIP OVOL2 PRKD2 SMARCC2 SF3A2 AP2S1 COG5 TSC2 RBM42 ECH1 HAGHL PAK4 TMEM44 TRAPPC9 TMPRSS9 ATG4D TRAK1 ZNF573 LZTS3 SIRT6 TCF3 TRIM62 CMTM8 ZMAT2 TIMM44 ESPN TRPV3 NELFA SPATA20 CSTF1 BEAN1 UNC119 LASP1 SLC38A10 DEPDC4 C4orf48 PPARGC1B NELFB GCC2 TMEM259 APRT ZNF514 SCAMP4 GGA1 RASAL1 STARD10 ARHGEF19 TEFM ECE1 SAMD11 NDRG1 CACTIN LRP8 SHKBP1 ABTB1 ADAT3 SMAD3 PC KLHL17 CERKL PPP2R2C PFKL RBX1 ECHDC2 SLC23A1 PRR5 GPR137 FBN3 RNASEL COL6A3 MYO7A CIC RAC1 NBEAL2 SH2D3A ZNF746 FAM83G CIZ1 FBXO2 SRC HSD11B1L	up	**
E2F1DP1_01	0.0032483	0.0366147	0.4317077	0.3296965	1.510851	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
E2F1DP2_01	0.0032483	0.0366147	0.4317077	0.3296965	1.510851	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
E2F4DP2_01	0.0032483	0.0366147	0.4317077	0.3296965	1.510851	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
E2F_02	0.0032483	0.0366147	0.4317077	0.3296965	1.510851	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
ASH1L_TARGET_GENES	0.0000000	0.0000057	0.7337620	0.2948253	1.510621	1134	ONECUT2 FAM227A MDM1 HJURP RUVBL1 CEP89 CDC45 TICRR ZNF273 C1QTNF6 ZMYND8 CHEK2 CCNB1 CENPF DROSHA GBAP1 C21orf58 GGCT KIF18B TTF2 CHCHD6 PIF1 BRCA1 CDCA7 CREB3L4 ZNF138 CDCA2 RACGAP1 ANKZF1 CABIN1 ASPM NABP2 MSTO1 FLAD1 SAP30L-AS1 IFT27 CDCA8 CENPA ECT2 ACOT8 TPX2 E2F3 CCNB2 ZNF714 GOLGB1 ZNF117 ERV3-1 CCNF TDRKH LIPE-AS1 ZWINT SMUG1 ZNF107 ZNF726 GOLPH3L WDR62 HMMR CLSTN3 RAB11B-AS1 CHAF1A BOD1 HLTF STAP2 EMC9 TP53BP1 CLHC1 BUB1 CCDC77 EEF1E1 TOP2A EXOC4 RPL32P3 AURKA EME1 CBX3 GTPBP3 KLHL25 CACNA1G COASY TMEM45A RAD54L MRPL27 PASK MCM3 ZNF226 CDC25C TRIM11 ZNF785 PYCR2 TARS2 RNFT2 CHD6 SARS2 CCDC148 C7orf50 ACTL6A CKAP2L NFYA PSMD4 CBY1 DNAAF3 ANKRD16 SPC24 BRIP1 EEFSEC FBXL19 MRPS30 PHB LRRC45 FADS2 CNOT3 ARL16 ERCC2 C4orf47 TULP3 INCENP CKS1B EFCAB11 ISOC2 CBX5 MRPL37 ANAPC5 ING4 CDK1 PABPN1 CDK12 EFCAB6 CCDC61 LMCD1-AS1 KCTD7 RFWD3 CCT3 NUDT2 PHF12 ANKRD54 AAGAB SUN1 GTF2E1 POLR3K UNG REEP6 DGAT2 PMEL RNF181 BPGM PSAT1 NARF KLHDC9 PAXIP1-AS1 FEN1 TSPAN31 EZH2 ZNF775 TNPO2 MRPS12 THAP8 RALGPS1 SAPCD2 OARD1 LCA5 TTC16 SNRPE RTP4 ZKSCAN5 STK11 IFT52 KPNB1 ANKRD39 TPD52L2 CHCHD2 SNRNP25 GIPC1 VBP1 GOLGA3 ZNF687 ILF2 EDEM3 CEP192 CDC23 AKR1E2 CCZ1B VIPAS39 DLGAP5 NEK10 SPG7 SLC26A2 PSMA5 MTOR ZNF133 FHIT UROS HIRA HMGN3 CCDC130 COX7C ACBD4 ROGDI COPS7B UBE2Q1 DPH2 ZNF417 TK1 PLEKHA8 PCSK4 CENPQ RHBDD3 AKAP8L ESCO2 MLEC ANP32E PKP4 NUDT16 ZNF300 AGPAT5 LAMTOR2 DAP3 LIN37 ZSWIM3 ZSWIM1 DNAJC11 TM9SF4 IQCH FKBP14 PRRG2 CCZ1 CCDC159 AAMP NAIF1 ELAC2 CCT7 NR6A1 CCDC137 CENPK TADA3 UBQLN4 CKAP5 PWWP2A PSMB3 ORMDL2 CENPM ZCCHC17 CA11 GBF1 RRP9 AP3M2 FAHD1 BCL2L1 NOL6 CDR2 ABCA7 MRPL24 ARVCF KDM4B WDR83 MED24 PRMT1 CKAP2 XRCC4 NOSIP MCM5 TDP1 ZRANB3 UIMC1 DDX23 C5orf22 LANCL2 SCYL3 RAB3D C1orf109 LRCH4 SNX11 ZBTB9 KATNB1 DOLPP1 POLR2I PDIA4 LSM4 RAP2B SUGP1 TMEM45B STK35 TCERG1 COPZ1 SPSB3 ZNF837 AP2S1 ZNF622 ZNF519 SH3D21 GLO1 ATP6AP1 FCF1P8 CYTH2 RPS26 APC2 MSH2 NCDN RBM42 ZNF195 PRR11 ZNF93 ZNF169 BBX DDX54 ZNF257 DENR ZNF66 RNF121 TXNL4B DOHH ZNF436 CEP164 PRPF31 NUBP2 ZNF384 NBR1 ZNF292 TOMM40L FBXW11 NLGN2 SRP9 LLPH PAXIP1 NME7 LINC00240 NDUFS8 AGBL5 TBCB ALKBH6 GNA12 BCAS3 BCL6 TMEM260 MAU2 CENPE POLR1A PFDN4 RHPN1 HGS TMEM256 ZNF526 PPIA PNN TTC9C RHPN1-AS1 SFXN5 DCAF11 ZSCAN20 TMEM38A TPRN SLC39A1 ZNF253 COX6B1 STK11IP TTLL5 FAM222B FTSJ3 TMEM161A MSANTD4 TRAPPC6A SETD5 ANKRD11 CYB5B PHRF1 CSTF1 CYHR1 COPE RTN4IP1 RCN2 MORN4 PDXP MBTD1 ZDHHC13 NSUN5 ZNF678 PPP1R13L PDK2 WDR63 UTP18 HRAS TRAFD1 PCNT CDK11B SRI TBC1D10B PPP2R5E PNPO FBXO5 LCMT1 ZNF688 CYB5RL ABHD2 TNPO3 FASTKD3 TMPO TOMM40 SLC2A8 ZNF774 SMYD3 GLRX5 ZNF77 TYK2 PMVK MPZL1 MTMR4 ZNF43 MTR HOMEZ TMEM167A MTRR TRIM59 HINT2 SHKBP1 MBD6 AP2A1 GDF11 WDR89 RMI1 HNRNPAB PARP16 PC LRPPRC FMN1 AFMID LYPLA2 MTHFD2 STRIP1 DHX38 CALM3 PAN2 METTL17 EVI5L ELMO2 ZNF675 SAP30L KLF5 WDR25 BBS12 DDX49 MAEA TUBGCP5 RAB4B STAG3L1 PDXDC1 ZNF691 CTPS1	up	***
MIR498_5P	0.0007351	0.0135108	0.4772708	-0.2804934	-1.509647	203	TRIM71 GCOM1 OSBPL11 LRRC8C TRPC3 BAG4 RTN3 DYRK1A KCNN3 VAPA TET2 MOB1B ZEB2 C12orf76 SEMA6D ATP2B1 MCTP1 PPP1R15B KLF6 FOXJ3 FAM122A TFRC PPP6R3 NOSTRIN DAB2 KLF7 ZBTB43 CAPZA2 TBC1D4 TLL1 NCOA1 CREBRF SYNPO2 TMTC1 NSMCE2 FERMT2 SKIL KLHL18 PCGF5 CREB1 LPCAT2 SNRK MEAF6 RHOQ YPEL2 CHORDC1 PHF3 NAB1 HBP1 GNA13 PDE4B ATAD2B MLANA POLR2M CREBBP B3GNT2 SKI GPR171 BMI1 CACNA2D3 IRF2 HIPK1 C5 CMPK1 EYA3 CD109 FAR1 PPIP5K2 PRTG	down	*
TGCCTTA_MIR124A	0.0000044	0.0003121	0.6105269	-0.2517082	-1.508499	495	SLC31A2 SEMA6A SASH1 EDNRB OSBPL11 KLF13 EMP2 PTPRE MBOAT2 PID1 EGR2 RGS9 DDX6 LONRF1 MYADM VAT1L RTN3 THAP2 QKI NR3C1 OTUD4 SYNC GGA2 PDE2A EDEM1 SEMA6D SH2B3 NFIX CACNA2D2 TACC1 TTL PCYOX1 LMNA C1orf21 ANXA5 LITAF MED26 AKT3 SPRY2 RAB14 TUBB6 PTPN12 EFCAB14 ROCK2 AHNAK LRRC57 PPP6R3 KLF4 ZCCHC24 PEG3 SLC7A8 MYRIP ABCC4 SNIP1 COTL1 RBMS1 GPR85 CCND2 FRMD4A UBE2B ELK3 ADIPOR2 CUL5 MPC1 OXSR1 ZNF706 KIAA0408 BACE1 TLL1 RSRC2 ZDHHC20 RAB6A MTPN KANK1 MYLIP MYO1C ETF1 VAMP3 SCN4B GZF1 PHTF2 PSEN1 CNTN3 MITF VAT1 KCTD12 GAS2L1 ETS1 DESI2 HIC1 JPH1 RHOG APBB2 FERMT2 SP3 PCGF5 CREB1 MAPK4 SLC10A7 PDZD2 FAM177A1 ITGA11 PPM1F ACSL1 BLOC1S6 CD164 SRSF6 PPTC7 EPHA3 PEA15 BAZ2B DYNC1LI1 HBP1 ANKRD13A NPTN GNA13 MACF1 IST1 RXRA GLTP SLC31A1 OPN3 EPN2 DCTN4 SLC25A20 FBXO30 TOB2 BRWD1 TMEM184B RBMS3 ULK2 TMEM109 LYSMD3 LIMCH1 STK4 PDE4A ARPC5 ANXA11 TMCC3 NRP2 NAA15 IQGAP1 WDFY3 MACROD2 USP48	down	***
MIR194_5P	0.0011018	0.0174326	0.4550599	-0.2866879	-1.506173	167	CXCL3 SLC12A6 OSBPL11 C18orf32 LPXN LRRFIP1 TTC7B EMCN QKI DYRK1A ERG HBEGF RNF125 REV3L DACH1 PPP3CA ATP6V1H FLI1 CPED1 PTPN12 MTMR6 BNIP2 LIN7C ZFAND5 TMED5 SEC24B MGAT4A CADM1 USP44 ELMSAN1 PRICKLE2 OSTM1 SLC10A7 NIPSNAP3B EPC2 CDK14 PPTC7 BTBD7 CHORDC1 RSBN1L TBRG1 NRN1 RXRA CEP170 SSH2 PARVA PAIP2 C21orf91	down	*
MIR19B_3P	0.0000037	0.0002797	0.6272567	-0.2495481	-1.504801	553	SLC31A2 EREG ABHD5 DLC1 OSBPL11 USP12 KLF13 SECISBP2L ADCY9 NUP54 RAPGEF2 ARRDC4 RCOR1 OTUD1 CCDC88A DDX6 LONRF1 QKI GPCPD1 BMPR2 S1PR1 MEF2A WBP4 EOGT MOB1B CCNL1 ZBTB4 UBL3 HECW2 RAPGEF4 RAP1A NLK KLF10 FOXP1 HIPK3 ADRB1 PLXNA4 MED26 ANKRD29 UBE2D3 RAB14 ATP6V1B2 FBXO8 ATP10A RHOB MTMR6 BNIP2 DENND6A REST SOCS5 KLF7 RBMS1 PDE3B HNRNPUL2 ID2 ARC PNRC1 CCND2 FRMD4A EPS15 CCSER2 ADIPOR2 MBD2 CLIP4 SLC6A6 PRICKLE2 FKBP15 KPNA3 AFF1 FAM76B NCKAP5 CNOT6L SRGAP2C BTG1 CREBRF VAMP3 PDIK1L VPS37A PKNOX1 PHTF2 LRRTM2 SGK1 KIF13A EBF2 SOCS3 APPL1 MAGI2 RAB8B HCFC2 C20orf194 ZFP91 DESI2 HIC1 PDE5A BMP3 ATP11A RABGAP1 BAG5 ATXN1L SKIL MBNL2 FAM43A KBTBD8 ATL2 GTDC1 HOMER1 ZNRF3 RASSF2 GRSF1 CD164 MSMO1 SRSF6 PPTC7 SLC35F1 MAPK8 TSHZ3 RIN2 FLNC BTBD7 EMC7 ZNF521 SMCR8 TGIF1 ZFYVE9 SBF2 YTHDF2 SKIDA1 ZBTB11 CNOT7 MAP3K2 ATXN1 HBP1 GABARAPL1 NPTN MACF1 PLAA SERINC3 ARPP19 INO80D SYT11 ARAP2 MIER1 WDR1 RTN1 EPN2 VPS4B CYP2U1 SP100 MEX3C BRWD1 G3BP2 RBMS3 LIMCH1 DOCK10 PTEN DUSP7 CAMSAP2 RORA ITCH LDLR C2orf42 DOCK4 NR3C2 WDFY3 DNAJA2 EIF4G2 DMXL2 AFTPH ZFYVE26 MB21D2 SERPINE1 AQP5 CFL2 CLIP1 ZNF385B HIPK1 ATF2 MAPK1 CLOCK CNGA3 DCUN1D3	down	***
MIR4498	0.0022572	0.0289402	0.4317077	0.3266508	1.503952	205	SLC9A3 PPM1H PCDHGA10 CPLX2 PKP2 ARMC3 PCDHGA9 JPH3 PCDHGA5 PCDHGA7 SDK2 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 CUEDC1 PCDHGB4 PCDHGA11 PCDHGA8 TNC OSBP2 TMEM41A PAQR4 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 PLXNA1 PROM2 CLIP3 EEFSEC PML TMEM178B TTYH3 ZNF346 PPIL2 IGFBP5 PACS1 FBXO41 LARP1 GPRIN1 RAB6B PCDHGA2 ARNT2 ACVR1B SRD5A1	up	*
MIR3960_MIR8072	0.0008553	0.0149814	0.4772708	0.9855653	1.503561	2	SLC9A3 WWP2	up	*
TTGCCAA_MIR182	0.0002614	0.0066793	0.4984931	-0.2664475	-1.503558	277	EPAS1 EDNRB KLF13 RDX INSIG1 BDNF TXNL1 BAG4 CORO1C MYADM CITED2 QKI AKAP7 DYRK1A ELMO1 MOB1B TEX2 NUMB SLC44A2 TACC1 EIF5 RNF144B CAMTA1 FAM122A TAPT1 DENND6A MVB12B VASP MAP1LC3B CEBPA KLF7 EPM2A DOCK9 GPR85 C9orf72 SHC4 ZMPSTE24 CUL5 N4BP1 PAFAH1B1 KPNA3 MARK3 FOXN3 MCMBP VAMP3 ADCY2 WASF2 SNAP23 C2CD2 MITF SP3 MBNL2 IP6K1 SPRY4 FOXO3 ABHD13 CBFA2T3 PCDH17 ATXN1 PPP3R1 TOB1 ADAM10 ETS2 SLC43A2 INTS6 YAF2 PARM1 RTN4 POLR2M RET FAM126B MMD PAIP2 CAMSAP2 DAZAP2 EVI5 STARD13 KLF15 BHLHE41 CLOCK ZFP36 EFNB2 MTSS1 WDR47 KCMF1 PCMT1 ATOH8 DR1 SKAP2 MEF2D	down	**
MIR1468_3P	0.0000025	0.0002136	0.6272567	-0.2492718	-1.503226	541	PRMT8 EREG GCOM1 IL1A SECISBP2L RBMS2 GATA2 CPEB2 RDX LRRFIP1 INSIG1 TMEM170B CD44 PLEKHF2 TMOD3 STXBP6 BMPR2 SRSF7 S1PR1 PRKAR1A MEF2A GALNT18 LAMP1 EOGT PPM1D CCNL1 ZEB2 DNAJB14 EDEM1 TRA2B TACC1 HECW2 PPP1R15B MTF1 PLXNA2 FOXP1 GLS GPBP1L1 PEX5L EIF4E DACH1 FOXJ3 PLXNA4 IL18R1 TRAF6 LAMTOR3 SPRY2 TFRC FBXO8 TIPARP AGO4 PRDM16 MTMR6 SCP2 KCNMA1 SORBS1 BNIP2 DENND6A LIN7C KLF4 RUNX1T1 ID3 TMED5 CEBPA SOCS2 KLF7 ZNF24 CLIC4 SNIP1 RBMS1 GPR85 CCND2 EPS15 CUL5 CLIP4 FAM76B NCKAP5 CNOT6L FOXN3 TMEM9B CREBRF VAMP3 PDIK1L PHTF2 HCFC2 PDCD6IP TMTC1 C20orf194 GLUD1 PDE5A BMP3 UHRF2 VPS26A SKIL SMU1 MBNL2 PCGF5 KBTBD8 FSD2 HOMER1 APH1B CGGBP1 EPC2 ZNF407 GRIK1 AGFG1 CTTNBP2 PPTC7 MAPK8 TSHZ3 XYLT1 NAP1L5 CR1 BTBD7 AKIRIN2 DDHD2 TMX3 TCF4 STRN SMCR8 DCK DPM1 ZBTB11 MCUR1 HBP1 GNA13 ATAD2B ARPP19 HELZ BMP2K GEM RBL2 ARAP2 INTS6 EXOC2 MIER1 ITPRIPL2 MGAT2 LMOD1 POLR2M PSME4 ZDHHC21 TBCEL BCAT1 TIMP3 FOXJ2 B3GNT2 TMCC3 LDLR NRP2 FAM13B GSPT1 WDFY3 PUM1 SPOPL	down	***
TGTGTGA_MIR377	0.0011480	0.0179972	0.4550599	-0.2859927	-1.501659	168	PRX HMOX1 EDNRB EGR2 QKI S1PR1 ARL8B AGPAT4 ZEB2 ZBTB4 CACNA2D2 FZD4 RNF182 CAMTA1 EIF4E NDEL1 CD93 ADARB1 TAPT1 KCNMA1 MVB12B GPR85 NCOA1 FOXN3 SRF HMBOX1 CPEB4 CUL4A ETS1 RABGAP1 PPM1F CELF2 GRSF1 FLNC BTBD7 AZIN1 NUP153 PHF3 BAZ2B C16orf72 CNOT7 ATXN1 MACF1 MIER1 LRP12 FBXO30 IPO5 PSME4 RET RNF38 GTPBP8 C21orf91 NRG1 NAA15 PUM1 REEP1 EGR1 CDON CDKN1B	down	*
CREBP1_01	0.0019461	0.0262122	0.4550599	-0.2882805	-1.496423	146	WEE1 RBMS2 MIR22HG LINC00472 CDC42 FBXO3 SH2B3 MCTP1 ZBTB21 ADRB2 GPM6A MAP2K3 AHNAK FAM76A KLF9 USP2 PER2 CADM1 ATF3 CALM2 CRTAC1 CRIM1 ID4 CNTF GABARAPL2 RHOBTB2 MBNL2 CDK2AP2 PREX2 DENND4A CELF2 SPRY4 CALM1 TNFSF13 TREX1 DAGLA TFEB ZFYVE9 TSC22D1 COL15A1 TOB1 PRDM8 SYT11 EPN2 SREBF2 JMJD1C ZDHHC5 PRKG1 FNBP1 STARD13 HERPUD1 CHIC2 AKTIP YRDC WDR47 EP300 ARHGAP44 NFIL3	down	*
MIR493_5P	0.0000145	0.0006920	0.5933255	-0.2591377	-1.496283	388	MGAT3 IL1A DENND5A TRHDE GATA2 CPEB2 LRRC8C RAPGEF2 TTC7B TMEM170B EGR2 OTUD1 RASAL2 CITED2 CDH13 VAMP2 HMGCR MEF2A DSCAML1 AGTPBP1 GNPTAB SH2B3 NLK FZD4 REV3L PAG1 DACH1 SLAIN2 FOXJ3 TCF7L2 ZMIZ1 HMGN1 FOXO1 KLF4 PRKD3 ZFAND5 FBXL3 NPR3 SEC24B DOCK9 NPAS3 M6PR FRMD4A PTGER3 CAPZA2 WASF3 CUL5 RSL24D1 KIAA0408 USP16 AFF3 NCOA1 PIAS1 BTG1 SERTAD2 FMNL2 KIF13A NDNF SF3B1 JUN JPH1 SHOC2 IFRD1 EEA1 SP3 PIK3R1 MBNL2 PCGF5 CREB1 SLC10A7 DENND4A NDST1 CELF2 TMEM128 SNX9 NECAB1 HIVEP2 USP7 HSF5 TCF4 MCUR1 NAB1 PIK3C3 MAP3K2 ANKRD12 POLK ATAD2B RXRA PRDM8 LDLRAD4 TNFAIP8 ZNF143 ITPRIPL2 SPARCL1 SEC63 ACAP2 LRP12 MFAP5 PTCH1 SSH2 KPNA4 MBD5 LIMCH1 SIN3A NFKBIA LTBP3 LDLR RHOT1 MT2A PUM1 PURB MIER3 PAPSS2 HAT1 REEP1 STARD13 VPS13D KALRN CDC14A CLIP1 GJC1 KCNJ6 ZNF385B HMGCS1 ENDOD1 HIPK1 CLOCK ITGB1 SLC38A2 KIAA2026 HP1BP3 FAR1 CTDSPL2 PPFIA1 WNT5A UNC50 MTSS1 TSC22D2 SERP1 RAD21	down	***
MIR381_3P	0.0000181	0.0008135	0.5756103	-0.2560964	-1.496281	382	USP12 EMP2 GPR65 PTPRE RAB3C BDNF FYN SEC22C CORO1C HEATR5B QKI BMPR2 GTF2I P2RY13 NR3C1 VAPA PPM1D IER2 SEMA6D CLCF1 UBL3 PPP1R15B CAMTA1 PEX5L ZNF697 SLAIN2 FOXJ3 PPP3CA ATP6V1H KDSR CWC22 EFCAB14 MAP2K3 FOXO1 SGTB SORBS1 MPEG1 ACSL3 KLF4 ITM2B CADM1 AXL PNRC1 ACTR3 MATN2 GNAQ KIAA0408 PAFAH1B1 KPNA3 HES1 RABGGTB CNOT6L USP25 RBPJ CREBRF RYBP PHACTR2 PPP6C PDE5A JPH1 EPC1 ELOVL7 IPO7 FYTTD1 SKIL MBNL2 MALT1 RC3H1 REL CGGBP1 TMEM128 AGFG1 PTP4A1 HIVEP2 SLC4A5 BTBD7 ZNF521 ATG2B ZBTB1 PDS5B CEP76 KHDRBS1 CNOT7 HBP1 ORC2 GNB4 CRY1 GNA13 RIMKLB PHF2 ARAP2 PDLIM5 SCN7A RTN1 ARIH1 PTCH1 ULK2 MBD5 LYSMD3 NFKBIA CEPT1 SCAI B3GNT2 KIF1B RORA ITCH RHOT1 ZFPM2 EIF4A2 NUP160 RAB2A YTHDC1 ABI1 PSIP1 KALRN ZNF800 LIN52 CLOCK FUS MYH10 XPO7 TRPM7 UBE2W WNT5A WAC MTSS1 AKAP12 TES PAXBP1 ARHGAP44 ZFYVE21 NR5A2 ITGA6 ORC4 NKTR RAB11FIP2 PLCB4 EDIL3 FNIP1	down	***
MIR548AZ_5P	0.0000253	0.0010591	0.5756103	-0.2595660	-1.496046	360	SLC24A4 EREG GCOM1 PPARG ZC3H12C DPYSL2 MBOAT2 BMP2 TMEM170B CITED2 BMPR2 MTMR10 STX11 OTUD4 MOB1B ACER3 ZEB2 KCNAB1 UBR3 EIF4A1 SGMS2 PPP1R15B PAG1 PEX5L PPP2R2A C1orf162 SLAIN2 PPP3CA HNRNPDL TNS1 PDE4D UBE2D3 TXN ADARB1 SCP2 SGTB PPP6R3 LIN7C ADO LEPROTL1 HAUS2 KLF9 STK17B ADAMTS9 SPAG9 NFKB1 AQP4 FRMD4A CAPZA2 WASF3 PIK3C2A CLIP4 SLC6A6 RBM44 KPNA3 CRIM1 NCKAP5 ADD1 NCOA1 C2orf69 TOPORS BTG1 SERTAD2 ETF1 RYBP PDIK1L PHTF2 PLGLB1 APPL1 AQP3 CPEB4 DESI2 RAPGEF1 SKIL CREB1 CXCL5 DENND4A TMEM128 AGFG1 SNX9 CCDC152 PBRM1 TCF4 CHRAC1 DCK CDC37L1 MAP3K2 ATXN1 MICU3 PHLPP2 PITPNA ADAMTS4 EPB41L5 THAP6 ARIH1 BRWD1 GPD1L POLR2M ZDHHC21 TBCEL BCAT1 RNF38 ABCA8 DOCK4 NABP1 SPOPL FEZ2 MIER3 YTHDC1 PLAG1 RBMXL1 CFL2 ZNF106 ATF2 MAPK1 CLOCK ITGB1 SLC38A2 HAS2 NAALAD2	down	**
MIR130B_3P	0.0001252	0.0038596	0.5188481	-0.2602822	-1.495955	344	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 CIT TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 PXK ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	**
MIR19A_3P	0.0000021	0.0001901	0.6272567	-0.2478310	-1.493699	550	SLC31A2 EREG ABHD5 DLC1 OSBPL11 USP12 KLF13 SECISBP2L ADCY9 NUP54 RAPGEF2 ARRDC4 RCOR1 OTUD1 CCDC88A DDX6 LONRF1 QKI GPCPD1 BMPR2 S1PR1 MEF2A WBP4 EOGT MOB1B CCNL1 ZBTB4 UBL3 HECW2 RAPGEF4 RAP1A NLK KLF10 FOXP1 HIPK3 ADRB1 PLXNA4 MED26 ANKRD29 UBE2D3 RAB14 ATP6V1B2 FBXO8 ATP10A RHOB MTMR6 BNIP2 DENND6A REST SOCS5 KLF7 RBMS1 PDE3B HNRNPUL2 ID2 ARC PNRC1 CCND2 FRMD4A EPS15 CCSER2 ADIPOR2 MBD2 CLIP4 SLC6A6 PRICKLE2 KPNA3 AFF1 FAM76B NCKAP5 CNOT6L SRGAP2C BTG1 CREBRF VAMP3 PDIK1L VPS37A PKNOX1 PHTF2 LRRTM2 SGK1 KIF13A EBF2 SOCS3 APPL1 MAGI2 RAB8B HCFC2 C20orf194 ZFP91 DESI2 HIC1 PDE5A BMP3 RABGAP1 BAG5 ATXN1L SKIL MBNL2 FAM43A KBTBD8 ATL2 GTDC1 HOMER1 ZNRF3 RASSF2 GRSF1 CD164 MSMO1 SRSF6 PPTC7 SLC35F1 MAPK8 TSHZ3 RIN2 FLNC BTBD7 EMC7 ZNF521 SMCR8 TGIF1 ZFYVE9 SBF2 YTHDF2 SKIDA1 ZBTB11 CNOT7 MAP3K2 ATXN1 HBP1 GABARAPL1 NPTN MACF1 PLAA SERINC3 ARPP19 INO80D SYT11 ARAP2 MIER1 WDR1 RTN1 EPN2 VPS4B CYP2U1 SP100 MEX3C BRWD1 G3BP2 RBMS3 LIMCH1 DOCK10 PTEN DUSP7 CAMSAP2 RORA ITCH LDLR C2orf42 DOCK4 NR3C2 WDFY3 DNAJA2 EIF4G2 DMXL2 AFTPH ZFYVE26 MB21D2 SERPINE1 AQP5 CFL2 CLIP1 ZNF385B HIPK1 ATF2 MAPK1 CLOCK CNGA3 DCUN1D3	down	***
GREB1_TARGET_GENES	0.0000169	0.0007694	0.5756103	0.2965366	1.493418	695	MUC5B ATP6V0A4 ALDH3B2 PPM1H SYT8 SCIN IGSF9 LAD1 CEP89 C1QTNF6 EPN3 RBBP8NL LRIG3 ZMYND8 S100A2 ANKFN1 RGMB-AS1 SDK2 PTPRH TMC1 PRR15L SLC27A2 SPAG17 NIPSNAP1 NAALADL2 CNTD2 SEC14L5 IFT27 NNT ANKRD22 STC2 RBBP8 DNAH3 CA12 GALNT10 C19orf57 TDRKH KIAA0895 SRPK1 VILL WDR90 SPPL2B DNAI1 GOLPH3L KCNH2 OSBPL2 STAP2 SMAGP TRIM29 TOP2A IQCD CARD10 GTPBP3 IFT43 KLHL25 ASCC2 ZNF860 RHOBTB3 TMEM45A AKAP1 C7orf57 LINC00511 XXYLT1 CCDC58 MCCC2 TGM1 CHD6 HEBP2 PROM2 ACTL6A ZKSCAN1 TBC1D8 CNGB1 EHF DNAH11 INPP4B GRHL2 CNOT3 WWC1 PARD3 DLG5 CCDC40 RECQL5 TMED3 ISOC2 CDKN2C CAPN8 PABPN1 EPHA1 SRRM2-AS1 RFWD3 ABHD17C RAPGEFL1 TNK2 ADAP1 POLR3K ABCC11 DGAT2 PMEL ENPP3 CCDC88C TMEM79 PSMG3 RNF207 FER1L4 IGSF3 VPS72 RECQL4 TSPAN1 KPNB1 ANKRD39 TPD52L2 PYROXD2 SNRNP25 DNMT1 VBP1 ZNF687 GRAMD1A RHOC AKR1E2 SPG7 NINL LLGL2 S100A16 PKP3 SALL4 C9orf152 CHTF18 TMTC2 CASP7 AKAP8L KIF21A ATG9B ANP32E RNF224 NUDT16 MAPK10 ZSWIM1 DNMBP ZNF282 CCDC159 ENC1 NAIF1 CCT7 DNASE1 SEC14L2 SLC26A1 LIMA1 PWWP2A DGKA KIAA0100 FAF1 AP3M2 KRT8 KDM4B EML6 MED24 VWA3B ANXA9 UIMC1 MAB21L3 SMIM6 IFITM10 TBC1D16 LRCH4 URB1 KATNB1 DOLPP1 RTKN OVOL2 RGMB SLC1A5 CORO2A CDH11 COPZ1 DOK7 CYTH2 PRR11 GRHL1 ECH1 CANT1 ANAPC2 CSNK1G2 BLVRB PAK4 SYBU OSBPL10 PRSS22 ARRDC1 TNKS1BP1 TRAPPC9 PPFIA3 ERGIC1 TCF25 ABCC5-AS1 CHD3 LRG1 DNPEP ERBB2 UNKL ALKBH6 BCAS3 CLNK RHPN1 FRMD6 NMT1 MCF2L2 EPHB4 UBE2C RHPN1-AS1 KRT80 TUBA1C TPRN SLC39A1 WIPI1 TTLL5 PLXNB1 UMODL1 ASCL2 PPP1R16A ANKRD11 PCTP FAM47E DAZAP1 LASP1 DNAAF1 ZDHHC1 MIOS RFFL PDK2 AKAP9 RBM20 COMTD1 GSTP1 SRI TMEM229B TBC1D10B SCAMP4 ABHD2 TMPRSS4 FAM111B EXOSC10 SLC2A8 RASAL1 NAV2-AS3 TRAF7 CDC34 STARD10 GLRX5 ZNF77 CHD8 BATF PIWIL4 MTMR4 KCNK1 MLLT3 SLC20A2 HOMEZ C1orf194 NDRG1 RAB26 EHMT1 NADK CYB561 AP2A1 ADAT3 SMAD3 RGS3 INHA FMN1 DENND2D	up	***
E2F_Q4_01	0.0038183	0.0412928	0.4317077	0.3258401	1.493229	197	CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A ORC1 EPHB1 RANBP1 WDR62 CASP2 MELK PAQR4 AP4M1 KNTC1 MAP3K13 POLA2 MCM7 PRKDC MCM3 TOPBP1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 POLE2 GMNN E2F1 UNG EZH2 TNPO2 THAP8 ZNF827 KPNB1 DNMT1 ZNF687 ACBD6 FANCG INTS7 NDUFA11 EPHB2 PCSK4 ANP32E DNAJC11 ETV4 KDM3A SASS6 PPP1R8 HMGA1 MCM6 SRSF1 GINS3 OVOL2 ATAD2 EIF3K PATZ1 PRIM1 RNF121 YBX2 ABCF2 RAD51 ARHGAP11A MXD3 SMC2	up	*
COREBINDINGFACTOR_Q6	0.0007541	0.0137238	0.4772708	-0.2744482	-1.488946	219	GPD1 SLC12A6 CD101 PPARG MIR22HG RAMP2 LMO2 BMPR2 CBL EPB41L3 IL23A ERG NFIX CYP17A1 B3GNT5 UBL3 PICALM CNTD1 LUZP1 HLX ZBTB8A NR4A1 ARHGEF2 DIABLO FLI1 MAFG MPL CCL3 CADM1 PDE3B VIM CCL4 XCL2 FCER1G EVI2A TBX5 IL7R PAFAH1B1 CRTAC1 ADD1 FOXN3 ETF1 RYBP BCAR3 RGS18 PSMA1 RHOG PDZD2 RASSF2 EPC2 TIGIT AZIN1 SRSF4 CD6 CYGB TAGAP CCR1 STON1 LTBP1	down	*
MIR548T_5P	0.0000320	0.0012760	0.5573322	-0.2583113	-1.485477	356	SLC24A4 EREG GCOM1 PPARG ZC3H12C DPYSL2 MBOAT2 BMP2 TMEM170B CITED2 BMPR2 MTMR10 STX11 OTUD4 MOB1B ACER3 ZEB2 UBR3 EIF4A1 SGMS2 PPP1R15B PAG1 PEX5L PPP2R2A C1orf162 SLAIN2 PPP3CA HNRNPDL TNS1 PDE4D UBE2D3 TXN ADARB1 SCP2 SGTB PPP6R3 LIN7C ADO LEPROTL1 HAUS2 KLF9 STK17B ADAMTS9 SPAG9 NFKB1 AQP4 FRMD4A CAPZA2 WASF3 PIK3C2A CLIP4 SLC6A6 RBM44 KPNA3 CRIM1 NCKAP5 ADD1 NCOA1 C2orf69 TOPORS BTG1 SERTAD2 ETF1 RYBP PDIK1L PHTF2 PLGLB1 APPL1 AQP3 CPEB4 DESI2 RAPGEF1 SKIL CREB1 CXCL5 DENND4A TMEM128 AGFG1 SNX9 CCDC152 PBRM1 TCF4 CHRAC1 DCK CDC37L1 MAP3K2 ATXN1 MICU3 PHLPP2 PITPNA ADAMTS4 EPB41L5 ARIH1 BRWD1 GPD1L POLR2M ZDHHC21 TBCEL BCAT1 RNF38 ABCA8 DOCK4 NABP1 SPOPL FEZ2 MIER3 YTHDC1 PLAG1 RBMXL1 CFL2 ZNF106 ATF2 MAPK1 CLOCK ITGB1 SLC38A2 HAS2 NAALAD2	down	**
PBXIP1_TARGET_GENES	0.0036331	0.0396343	0.4317077	0.3277552	1.485171	178	HMGA2 KLC3 KRT5 ACY3 TSHZ2 PLEKHA6 ZP3 B4GALNT1 GLB1L3 HOXB7 PAH DTX3 ZFP64 SMUG1 PPIAP22 FBF1 MED12L CDCA5 PDCD5 WDHD1 CHAD ASS1 ACSF2 C2orf72 XRCC1 TMEM178B FADS2 IGLV1-40 KNSTRN NCAPG2 GRB14 KRT18 DMKN VWA2 AP3D1 FAM114A1 ZMIZ2 PMEL TRAPPC12 KCTD1 DNMT1 EVC2 SGSM3 ACSL6 ENTPD8 KIAA0100 AAAS KCNIP3 LIPG TTC34 KIF21B WDR83 CYP2S1 ZDHHC11 RPL39P3 GRAMD1B VIPR2 ACP1 TNS3 MMP17 MAU2 TCF3 RANBP3 WIZ ATG4B PARP2 PRKAR1B BCKDK SHROOM1	up	*
NFKBIA_TARGET_GENES	0.0000016	0.0001535	0.6435518	0.2911378	1.483388	888	KIF1A ATP6V0A4 PPM1H NPC1L1 ZDHHC8P1 ENTPD2 CEP72 EPHB3 KRT5 ACY3 GALNT6 C5orf63 B4GALNT4 NEK2 EYA2 SLC9A2 PPFIA4 IQCE JPH3 PBK KIF18B CHRNG GAL3ST1 CHODL PPP1R14D ALDH1L1 IGHJ3P CABIN1 POLE ESPL1 B4GALNT1 TFDP2 PHLDB3 CYP4F11 GALNT10 EIF3B MUC20 GON4L LIG3 ARHGAP40 AOC1 PCDHGA8 ASTN2 WDR90 GSDMB CEP250 PPP1R9A RUVBL2 POLR3A OSBP2 STRA6 CLSTN3 LAMC2 CUL9 COPG1 CYP24A1 FRS2 GPER1 ITGB4 P4HTM SEZ6 SYCP2 DOC2GP MAD1L1 IL12B ABCC5 GALNT9 GNAS-AS1 LIPE BRPF3 NME9 KLHDC4 PKM ENTPD6 BEST4 PASK SLC12A7 WDR60 SLC9A3R1 NEB EPHA10 PFKP TBC1D8 TRMT2A RPAP2 DSCC1 B4GALT7 DDR1 HSF4 RABEP2 TRGV1 PPP5C TMEM178B ATAD3C THPO FLNB TRPV4 MGAT4B SLC25A10 DLG5 DBNDD1 PPP1R37 BTBD2 RECQL5 PES1 THOP1 DDX51 SUPT5H PAK1 KRT18 CROCC SSUH2 PICK1 TNK2 DMGDH JAKMIP1 RBCK1 ABCC11 SYN3 KIF19 LARP1 KRBA1 TTC6 SPAG5 RAB11FIP4 LIPT2 TCTE1 CCDC57 ZNF827 RECQL4 YEATS2-AS1 SUSD4 TEP1 PYROXD2 ELMOD3 ST14 EXOC7 AMPH ADAM12 RBFOX3 EFCAB2 LMNB2 GALNS PLEKHG3 PIGG SPTBN5 LMF1 FBXO15 DNM1 CADM4 DBN1 ENAH URGCP ATG9B HIP1R SPTBN2 PKP4 MAPK10 CLTA DAP3 LIN37 LRWD1 ENOSF1 AHNAK2 TTLL10 ACSL6 SIL1 GALNT7 ELAC2 CNDP2 RAD50 SMURF2P1 TNK1 P4HA1 DHRS1 MDGA1 NAGS CDC20 ANKRD6 NPRL3 KCNIP3 ASCC1 CATSPER2 FIBCD1 ARHGAP22 SH3GLB2 ABCA7 IGFL2 KRT8 ZNF320 TTC34 ADAMTS12 BLCAP ZNF558 EML6 CDC42BPG ZSWIM8 BSN SSH3 IGHJ5 SNAP47 NSD1 RTEL1-TNFRSF6B CYP2D6 LRIG1 STMN3 NDUFS7 NEURL4 LRRK1 CYP4F12 POLR3E SUGP1 SLC41A3 NT5DC2 GAD1 ERGIC3 SH3PXD2B U2AF2 MVP TC2N MST1P2 ESRRB GNAL KLHL7 DOK7 CEACAM5 ALMS1 ENGASE GLIS3 ECH1 GTF3C2 RTEL1 CSNK1G2 STAT6 ACSF3 DLEC1 TRAPPC9 ZFP14 MROH1 KCNQ3 IGHJ6 GRM6 TCF25 CHD3 LRG1 TMEM101 PTPRF ERBB2 ARHGEF39 RAB43 BCAS3 PNKP B4GALNT3 ZSCAN29 FLNB-AS1 FBLIM1 MYO15A CHL1 SRPRB BCAN TIMM44 RANBP3 TAF4 CAPN9 SFXN5 SLC35G1 RIPK3 NPEPL1 RNF144A-AS1 SART1 OAS3 SPATA20 KHNYN STK11IP ZBP1 PTPN13 PPP1R16A FBXL18 CORO1B SPATA33 DLEU7 TPM1 SUMF2 BEAN1 DAZAP1 ZNF740 LINC01088 USP20 PSTPIP1 SLC38A10 MUS81 DYNC1H1 BMF MROH7 ZNF619 MAN2C1 MED15 WDR63 HRAS SIGIRR ZNF598 PCNT ST6GALNAC1 CAMK2G NUDT22 DEPDC5 FOXP2 ZNF276 SMOC1 SH3PXD2A NFE2L1 MEGF11 SLC2A8 TLE2 CTU2 STARD10 TYK2 KRT18P61 RNF40 GAK TPPP3 D2HGDH CXXC1 RUFY1 PCBP4 CACTIN RAB26 SHKBP1 HERC2 GGA3 KEAP1 RETSAT TTC13 RGS3 TMEM175 PC OLFM2 ZDHHC11B CSMD1 KSR1 ANK1 TAOK2 CTC1 UVSSA PPP2R1A KCTD6 KLHL17 EVI5L WDR25 DNAH9 DLGAP2 POLD3 CACNA1A PTPN23 TFAP2C IPO4 SFRP5 VPS4A CAPN1 PNPLA7 RMI2 NDRG4 PPP1R32 ECHDC2 ITPA ACOX2	up	***
MIR3143	0.0000480	0.0017560	0.5573322	-0.2540843	-1.481076	381	RTKN2 AKAP5 MRPS18C ZC3H12C ST6GALNAC3 RUNDC3B KLHL8 EMCN TMOD3 RASAL2 GPCPD1 SFR1 IDI1 NR3C1 SLCO2A1 B3GNT5 LIFR LATS2 PBX3 FZD4 ZBTB21 GLS SLC7A11 DACH1 SRSF2 HNRNPDL SPTBN1 ZEB1 PDE4D SETD3 ZYG11B ATP6V1B2 ATP10A PER3 NRARP MTMR6 SRSF5 LEPROTL1 UHRF1BP1L STK17B MAP1LC3B TMED5 GAPVD1 FBXL3 NPR3 UBQLN1 CADM1 CXCL2 AQP4 ATP6V0D2 ZBTB43 PIK3C2A CNOT6L C2orf69 RAB6A RBM39 CREBRF ID4 PDHX PRDM11 DNAJC27 CTSS PHACTR2 HECA RASSF10 NSMCE2 ARHGEF10 FOXN2 THUMPD1 CREB1 OSM SLC10A7 PREX2 CGGBP1 AGFG1 UBB PTP4A1 FOXO3 CCDC85A IRF5 AZIN1 GOLGA8R HNRNPA2B1 SBF2 GOLGA8H MAP3K2 RELL1 PLSCR4 CSDE1 KANSL2 NRN1 MBNL1 RNF2 BMP2K RBL2 RNF138 RTN1 CYB5R4 USPL1 TAB2 ARHGAP18 NSUN4 OSER1 SCAI B3GNT2 FAM126B GTPBP8 ZFPM2 EIF4A2 SLC44A5 ANO6 GRPEL1 SLC35A1 DMXL2 PSIP1 ACVR1C CHML SPPL2A ZNF800 HIPK1 TGOLN2 C16orf95 SH3GLB1 NOG KMT2E PLXDC2 BBS7 TRPM7 UBE2W PIAS2 VSTM4 UBE2N TRIM13 MATR3 IL5 CRIPT TYRP1	down	**
E2F_03	0.0032329	0.0366147	0.4317077	0.3210140	1.478895	206	GRIA4 CDC45 GPAT2 PRRT2 CDCA7 AGFG2 E2F8 NABP2 CDC6 PLD5 E2F3 GAPDH MCM4 MCM2 CDC25A ORC1 CAND1 EPHB1 RANBP1 MELK PAQR4 AP4M1 KNTC1 SEZ6 POLA2 CACNA1G MCM7 PRKDC MCM3 LIG1 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 GMNN E2F1 UNG EZH2 LRRC56 DNMT1 ZNF687 FANCG INTS7 CCDC151 PCSK4 ANP32E DNAJC11 RHD POLD1 MARCKSL1 NR6A1 SASS6 KLHDC3	up	*
MIR4325	0.0010430	0.0169191	0.4550599	-0.2696886	-1.475005	230	KMO DLC1 SGK3 CPEB2 LRRC8C INSIG1 EGR2 RGS9 GTF2E2 CALCRL ZCCHC2 PCOLCE2 DYRK1A NFIX EMILIN2 ITGA5 EIF5 PLXNA4 RAB12 PTPRO BNIP2 REST RRM2B GAA ARNTL MYO1B MYRIP SNIP1 ATL3 TEF UNC5A AFF1 MOB3A FRY SYNPO2 PDCD6IP C20orf194 HELQ ZNF804A KBTBD8 PDZD2 TRAK2 THSD7B YWHAZ ATG3 KLRC2 BAZ2B ACADL NPTN GATA6 PITPNA RTN1 ACTB RBMS3 FNBP4 NHLRC3 JMJD1C RNF38 MMD TMCC3 RORA KLRF1 KALRN BHLHE41 ADAMTSL1 HIPK1 CLOCK SLC38A2 PLXDC2 CCDC93 SCAF11 SGPP1 CHKA ZFYVE21 ROBO2 DOCK5 FNIP1 NR4A3 CCNC SEMA5A SREK1 KLRC1 ADCY3 OTUD7B ZFHX3 ZNF430	down	*
STAT4_01	0.0008220	0.0147437	0.4772708	-0.2706106	-1.472419	214	HSPB7 SOSTDC1 PDLIM2 ODF3L1 HHEX BDNF LPL CITED2 P2RY13 FGF10 ABCB1 ZEB2 ERG SH2B3 UBL3 EIF1 BZW1 HIPK3 TTYH2 NR4A1 PDE4D UBE2D3 FLI1 STAT5A CASKIN2 SDCBP NPNT CLEC1A LEPROTL1 USP2 EPM2A RBMS1 CXXC4 ELMSAN1 PTCHD4 TLL1 FLT1 SGK1 DHH MITF CPEB4 ETS1 RHOJ FYTTD1 GRIA1 PDZD2 LETM2 RHOQ BCL6B RUNX3 RIN2 HNRNPD CPA3 VAV3 DOK3 LRRC32 MBNL1 RNF138 LAT ARPC2 OSR1 RASSF8 JMJD1C EDN1 MTUS1 DOCK4 NRG1 EMC3 FEZ2 GREM1 ZNF385B CLOCK PRKCH SLC38A2 NDFIP1	down	*
BARX2_TARGET_GENES	0.0000000	0.0000019	0.7614608	0.2857431	1.471913	1491	FOXM1 SPATA24 HOXB-AS3 MDM1 FAM81A RUVBL1 CEP89 CDC45 TICRR ZNF273 C1QTNF6 TROAP RPGRIP1L ZMYND8 CHEK2 NEK2 CCNB1 CENPF DROSHA UBE2T GGCT TTF2 CHCHD6 PHF14 MKS1 PLEKHH1 PIF1 BRCA1 C12orf66 CREB3L4 ZNF138 MRPL46 GINS1 ANKZF1 E2F8 IFT122 KIF14 TRAIP ASPM NABP2 STIL NNT-AS1 MSTO1 FLAD1 IFT27 CDCA8 AURKB CENPA ECT2 ACOT8 TPX2 TFDP2 NNT CCNB2 ZNF714 GOLGB1 RAD54B XPNPEP1 CDC25A PRC1 APOL2 TDRKH LIPE-AS1 CAND1 RCCD1 AVL9 ZWINT DZANK1 CCT2 DCTN2 UQCC1 TRIM45 LSM5 ZNF726 NME1 AARS2 GOLPH3L RUVBL2 POLR3A ZSCAN2 BZW2 LTB4R2 RAB11B-AS1 SMARCC1 KIF23 CHAF1A QTRT1 STAP2 EMC9 TP53BP1 AP4M1 BUB1 CCDC77 MSX2 TOP2A EXOC4 CCT5 CENPL RFXANK IQCD NUP155 WDR3 C1orf226 SAE1 GTPBP3 VASH2 TPR KIF2C MCM7 MPHOSPH9 C14orf93 TPCN1 GALNT9 RRM2 LIPE MDFI BRPF3 ZNHIT6 RAD54L ERAL1 BLOC1S1 CDC25C MCCC2 ZNF785 TARS2 RNFT2 LETMD1 CHD6 OAZ3 SARS2 ZNF443 CCDC148 C7orf50 IFT172 ORC6 ACTL6A NFYA PSMD4 RAD51AP1 DNAAF3 TIMM50 SPC24 MRPS11 ZNF48 BRIP1 ETFA FNTB FDXR BLM MRPS30 PHB LRRC45 FADS2 SYMPK C2CD3 FBXO16 CNOT3 ARL16 ALDOA ERCC2 TFCP2 SRRM5 PPP1R37 INCENP CKS1B EFCAB11 ISOC2 C12orf75 FRMD5 CBX5 PAK1 MRPL37 ANAPC5 CDK1 PABPN1 DNAH6 EFCAB6 CCDC61 EXOSC2 LMCD1-AS1 RFWD3 CENPH PICK1 CCT3 NUDT2 ANKRD54 ADAP1 TYW1 POC5 ITGB8 UNG STX18 STAT2 SEC61G PMEL RNF181 BPGM KIF2A ZNF584 PSAT1 ANAPC7 FEN1 TSPAN31 SPAG5 TNPO2 C16orf71 POC1B MRPS12 METTL3 OARD1 TNRC18 LCA5 NAPEPLD TTC16 NOP2 DIAPH3 CENPP SEMA4F ZKSCAN5 KPNB1 CHCHD3 TPD52L2 CHCHD2 HYKK POLR2H GIPC1 LGR5 ZNF687 FANCG UBFD1 CAPS2 ILF2 EDEM3 CEP192 UQCRFS1 CDC23 AKR1E2 DCLRE1C DLGAP5 C19orf44 ATP7B DCAKD NEK10 WDR53 SPG7 SLC26A2 FOXRED1 PSMA5 AGL MTOR ZNF133 SNRPA MNS1 FHIT MBD4 YIPF3 DHODH C19orf12 PLEKHG3 ZMAT5 GPRC5C SUDS3 ACBD4 COPS7B DPH2 TK1 TRAM1L1 PLEKHA8 CENPQ AKAP8L HDAC1 ESCO2 MLEC OS9 CCDC146 MRPL4 ANP32E PKP4 NUDT16 ITFG2 TCEA1 STX18-AS1 BTN2A3P LIN37 SPA17 ZSWIM3 ZSWIM1 NDUFA13 CCDC51 FKBP14 CCDC159 HLA-A PPME1 NAIF1 ELAC2 CCT7 IP6K2 CENPK GEMIN6 LIMA1 CKAP5 CPSF4 L3MBTL2 PWWP2A PSMB3 CDC20 DGKA ORMDL2 PALB2 CENPM WDR34 ZCCHC17 CCDC30 GBF1 C12orf65 RRP9 AP3M2 MRPS23 NOL6 CDR2 ABCA7 CDK5RAP2 MCM6 KDM4B METTL2B WDR83 RPL7L1 MED24 LPCAT4 PRMT1 ZSWIM8 CKAP2 UTP20 MCM5 ANKS3 CD2BP2 TDP1 ZRANB3 SNRPD1 C5orf22 FAM161A SCYL3 ZNF563 HAX1 RAB3D C1orf109 ZBTB9 DOLPP1 POLR2I CYP4F12 CREB3L2 CCNG1 MIB2 RAP2B RSPH4A AP4B1 LRRC46 GOSR2 EIF3K TCERG1 COPZ1 ALG8 SPSB3 PRMT5 ZNF837 ZNF519 MICAL3 AMN1 GLO1 ZNF212 CYTH2 RPS26 RBM42 ULK4 ZNF195 PRDM10 BBX BANF1 TXNL4B PAK4 PDAP1 STAT6 ACKR2 CEP164 WDR77 PRPF31 NUBP2 CAPN10 MAP3K9 NBR1 RNF123 PFKM KCTD21-AS1 NLGN2 ENKUR GTF3C5 MRPL9 SRP9 TYSND1 IKZF4 NDUFS8 ERBB2 NUBPL CPOX TBCB UBAP2L SNUPN ALKBH6 ZNF131 GNA12 BCAS3 POLR1B TARBP2 TCF3 ANKMY2 ZMAT2 ALG1 GGCX MTHFD1 PDZD7 NMT1 HGS TIMM44 TMEM256 ZNF526 UBE2C FBXO45 NCAPD3 SFXN5 ENO1 BTN2A1 PPP2R5D ZSCAN20 TMEM38A MRPL48 SLC39A1 COX6B1 TTLL5 ILVBL FAM222B CALU HEMK1 DDX41 TMEM161A MSANTD4 TRAPPC6A SETD5 ANKRD11 CYB5B RPUSD3 COPE TOMM7 RTN4IP1 XPO6 HEXIM2 RPL23A VPS26B MORN4 PDXP MBTD1 ZNF678 ASB16-AS1 MAP3K12 PDK2 WDR63 SH3RF2 PLK4 UTP18 PTPRK TRAFD1 PRPF19 MST1 TMEM259 TBC1D10B APRT PPP2R5E PNPO FBXO5 PSMB10 ZNF688 HUWE1 CYB5RL MRPL43 ABHD2 TNPO3 FAM111B NFE2L1 FASTKD3 KIFAP3 NSL1 ZKSCAN4 TMPO TOMM40 SLC2A8 ZNF774 TIMM10 SLC4A1AP TRAF7 NHP2 GLRX5 ZNF77 TYK2 RNF8 IMP4 MTMR4 DCLRE1B RNF40 GCSH MTR DLGAP4 OSCP1 HOMEZ RPLP0 MTRR SHB CACTIN IMP3 RBM26-AS1 HINT2 SHKBP1 CS ZNF524 TMEM67 AP2A1 WDR89 RMI1 HNRNPAB TIPIN PC DTX4 FAM149B1 FMN1 AFMID MCCC1 PSMD3 PPP2R1A MTHFD2 DHX38 RPL41 CALM3 SWSAP1 PAN2 EVI5L ELMO2 GARNL3 KLF5 DDX49 HHIP SLC25A35 SLC12A9 SCAND2P	up	***
FOXN3_TARGET_GENES	0.0000007	0.0000848	0.6594444	0.2871733	1.470795	1130	CCNO SIM2 ATP6V0A4 CEACAM1 SLC16A14 HS3ST1 EGLN3 MDM1 FAM182B WFDC3 PKP2 EPN3 C2CD4A PDCD6 ZNF84 HOXD8 LRRC43 EYA2 ARMC3 HOXB6 PAGR1 IQCE TOX3 MKS1 PRRT2 CCDC113 SORD BRCA1 FANK1 PTPRH GPR35 CABIN1 FGF11 NPAS2 BCAS1 TTC26 CDCA8 CCNB2 KNOP1 SMPDL3A PRKCA MYBL2 DNAH3 CKLF-CMTM1 FERMT1 PRC1 HNF4G LIME1 ARHGAP40 ZFP64 DZANK1 CDT1 LRRC27 COX11 UQCC1 WDR90 LMLN SIPA1L3 CEP250 RSPH1 TTLL4 ZNF862 HMMR BTRC MUC6 KIF23 C9orf116 SPAG16 CUL7 EMC9 FOXJ1 TSGA10 FBXW9 MAP3K13 EEF1E1 FBF1 KCNMB3 DPY19L1 THBS4 REC8 SLC2A10 TMEM177 ITGB4 C20orf96 ODF2 SYCP2 CACNA1G LPIN3 SPEF2 RNF157-AS1 ASPHD1 EFCAB12 AKAP1 ANKEF1 ENTPD6 SLC4A11 DCDC2 PASK TRPT1 SNHG11 LINC00511 TGM1 ANG SALL2 SMYD5 WDR60 CCDC148 NEK11 PROM2 ORC6 CKAP2L KIF3C C2orf72 EHHADH TBC1D8 SPATA17 SNORA71D SAMD10 LRRC45 C4orf47 STXBP4 CCDC40 CKLF THOP1 ZCRB1 EXOC3L4 EFCAB11 NRSN2 ETV7 SUPT5H PAK1 KIAA0556 LRGUK LRRC6 PPM1E CEP97 DNTTIP1 SMG1P1 FAT1 DIDO1 ARPC1A GNB1L NUDT2 TTLL9 KIAA0753 ATIC DCBLD1 GMNN DIS3L2 FBXO41 PSMB5 MRPS2 ACTR3C RUFY4 LINC00639 ENPP3 ANAPC7 CPNE1 DYNLL2 MIR3939 SLC35F3 TRAPPC12 TTC16 NLN CBX1 TCTE1 CCDC57 CBFA2T2 SEMA4F FGFR1OP ANXA2R IFT52 KANSL1-AS1 UBN2 EIF6 EFTUD2 HSPA4L DENND6B SPEF1 CAPS2 ZGPAT BBS5 NPHP1 EXOC7 RGS17 ATP7B RABL2A SCLY DTX2 NEK10 MRGBP NFS1 SPG7 COA3 DNAH7 TSNAXIP1 ADNP RBFOX3 ATP9A MNS1 DHRS4-AS1 LLGL2 GALNS COG7 PIGG GPRC5C HIRA IQCG RGS22 HMGN3 RBM12B FBXO15 MORN2 COPS7B ZNF544 NFATC4 ARHGAP5-AS1 CNGA4 POMT2 IQCK HECTD1 HID1 PKP4 TEKT3 ZSWIM3 SLC4A2 ANAPC1 FHL2 SYNGAP1 FUCA2 SND1 TTLL10 C12orf73 NUP85 FBXO44 TRAF3IP1 CLTB TMEM232 AAMP TCEA2 CCT7 RAD50 KDM3A CHPF TMEM234 GTF3C1 UBE2O PPHLN1 KLHL23 KCNB1 EFCAB10 AGBL2 VPS25 AAAS ZCCHC17 CCDC30 EFHC1 DUS1L TCTN1 ZNF497 BCL2L1 USP2-AS1 BAD CDR2 PEX5 MGME1 FAM174A ACTRT3 FAM183A PIGU ROMO1 TDP1 SIRT5 TMEM198 DPY19L2 DYNC2H1 NEK4 FAM161A RTEL1-TNFRSF6B C1orf109 TBC1D16 FBXO36 ZBTB9 RTKN TTLL6 WDR45B RPP38 WDR27 NEDD8 GAD1 LRRC46 OGFR CDH11 U2AF2 PRMT5 ARFGAP1 STRBP SPAG4 B9D1 ALMS1 MAP3K14 TTC12 GRHL1 CAP2 DDX54 RFC5 DTNB USP39 ACSF3 INO80E MLLT6 CARHSP1 STK25 R3HDM4 CHMP1A ARHGAP5 ZNF217 TEPP RUNDC1 KIAA0825 SOX12 CDK5 DNPEP AGBL5 TMEM101 NUBPL LZTS3 CASC2 ENTPD7 GMPR2 C1orf159 EARS2 TRIB2 PGPEP1 ALG1 GGCX MON2 SRPRB NEIL1 MCF2L2 HGS MRPS27 SIGMAR1 CDC25B UBE2C LINC00205 TAF4 FRZB GPN1 ARMC10 NELFA FOLH1 SPATA20 CCDC91 PPP4R4 STK11IP ZNF367 TK2 TTLL5 TRUB2 ATG4B MOK MZF1 PPP1R16A TRAPPC6A PCTP ANKRD13D GEMIN2 SPATA33 SARDH TOMM7 RTN4IP1 PGM5P2 INO80B ATP6V1C2 NDUFAF6 LASP1 DHX57 ARMC2 DNAAF1 ZNF316 ZDHHC1 SLC40A1 SEC31B SHQ1 MAN2C1 VPS16 REXO1 RAB40C MFSD9 RANBP10 GSTP1 PEX11A NUDT22 TBC1D10B ROPN1L PSME1 NFE2L1 LAMA5 RNF175 MECOM KIAA1841 MCEE ZNF414 TCFL5 FHAD1 GLRX5 SCUBE3 CCS LINC00271 CACNB1 SLC2A4RG TASP1 MLLT3 SAMD12 DLGAP4 OSCP1 ALS2 DHX32 CXXC1 ABCD3 KIF6 MRC2 TMEM67 CYB561 CEP112 XRCC5 MTF2 SIX5 GPRC5B CDH24 NCOA5 THAP4 SLC7A6OS E2F4 ZC3H18 TMEM219 HENMT1 HAAO WDR25 SAMD14 DNAH9 POLD3 PIFO PDXDC1 COQ4 TFAP2C IPO4 ZNF839 METTL9 TRAPPC2L HM13 SNHG10 NDRG4 DNAL1 MSL1 RCAN2 SLC4A7 LRBA ZNF460 PPM1G WBP1 SDHC	up	***
ZBED4_TARGET_GENES	0.0029895	0.0349648	0.4317077	0.3136622	1.470771	248	KIF20A MND1 PHF14 IFT122 DGCR8 UQCC1 FAM220A AP4M1 TSGA10 CLHC1 NUP155 POLD2 MCM7 LPIN3 MORN1 CMBL CDC25C GET4 TRMT61B MDM2 SPC24 DDR1 PIGO TERC NUSAP1 HARS2 CENPJ AAGAB SLC16A13 SEC61G KXD1 LIPT2 TSPAN1 ZKSCAN5 IRF6 EFTUD2 ZNF687 PARS2 CAPS2 TAPBPL PSMA5 MNS1 MAN1B1 MBD4 S100A16 MLEC SOX2-OT GEMIN5 CD27-AS1 IQCH LTBR YARS2 NIF3L1 CCDC137 PWWP2A BRD8 DGKA HMGB3P22 KRT8 ANKIB1 KPTN RPP38 LRRC46 MST1P2 RER1 HEATR5A PDAP1 AP001372.2 RAD51 ZNF384 UQCRQ C1orf159 DNAJC14 ADAM15 MRPS27 CYSTM1 NELFA DCAF11 PI4KB STK11IP DDX41 TEX9 NDUFAF6 WDR55 SFXN2 DHDDS MRPS16 MLH3 SH3RF2 TRIM52 DFFB CRB3 PNPO	up	*
GTGCCAT_MIR183	0.0034766	0.0384907	0.4317077	-0.2834578	-1.470370	151	GREM2 TTC7B QKI CTDSP1 YPEL5 NR3C1 USP47 SEMA6D KIAA0355 HBEGF BZW1 FOXP1 PPP2R2A SRSF2 MAPK8IP1 PDE4D MTMR6 TLE4 FOXO1 ERP44 TMSB4XP8 PPP2R5C FAM76B BTG1 PPP2CA VPS37A PLEKHA3 RAB8B FOXN2 SNX1 UNC13B CELF2 DAGLA ING3 PPP2CB C16orf72 PIM1 GNG5 MBNL1 ARPP19 AMD1 BNIP3L RNF138 EPHA4 MAP3K4 SIN3A ZFPM2 SPOPL SLC35A1 ZFYVE26 ARHGEF18 EGR1 PLAG1 CFL2 ITGB1 CSNK1G3 SRSF11 PTDSS1	down	*
LET_7C_3P	0.0000104	0.0005731	0.5933255	-0.2460435	-1.469316	508	CXCL3 FOXF1 TAL1 USP12 CD55 KCNA2 CPEB2 PRKG2 RDX RAPGEF2 THBD PTPRB BMP2 TMEM170B OTUD1 MED4 NEDD4L CITED2 HMGCR NR3C1 DSCAML1 GNPTAB TSHZ1 MOB1B ZEB2 SH2B3 TRA2B UBL3 MCTP1 HECW2 MAP3K8 RANBP9 NLK SLC7A11 DACH1 SLAIN2 FOXJ3 PPP3CA SPRY2 HNRNPU TCF7L2 GPM6A ATP6V1B2 FLI1 ZMIZ1 HMGN1 STAT5A FOXO1 KCNMA1 PPP6R3 DENND6A KLF4 COQ10B RRM2B KLF9 DAB2 ZFAND5 FBXL3 KIF26A FAM49B FMNL3 DOCK9 NPAS3 UBE2E2 PTPRC ARHGEF26 M6PR PTGER3 CLK4 RNF139 PPP2R5C SLC6A6 RSL24D1 FAM76B AKIRIN1 TANC1 SERTAD2 CREBRF PPP2CA RGPD3 PHTF2 KIF13A EBF2 SF3B1 MITF LRCH1 SHOC2 ELOVL7 FERMT2 SKIL SP3 FBXL16 MBNL2 PCGF5 HERC1 PRKCE ATP13A3 SLC10A7 MORF4L1 YPEL2 NECAB1 HIVEP2 NAA16 BTBD7 TSPYL6 SRSF4 TSC22D1 GNAI1 KHDRBS1 MAP3K2 PPP3R1 GNB4 ANKRD12 NPTN GNA13 RIMKLB PHF2 ADAM10 MBNL1 ATAD2B RXRA CEP170 SEC63 CXCR4 CDKN1C LRP12 CYB5R4 ZDHHC21 GRIN3A ISCU KPNA4 MBD5 PALD1 CUL3 SIN3A NFKBIA JMJD1C PDE4A NALCN GPR171 RORA COL13A1 DOCK4 GRB10 TLK1 WDFY3 PUM1 BMI1 MIER3 DNAJA2 ZBTB44 HAT1 PIM3	down	***
MIR548AU_3P	0.0031142	0.0356518	0.4317077	-0.2829987	-1.469005	146	FAM167A PHACTR1 RDX MED4 CDH13 MTMR10 C3orf70 PKHD1L1 MTF1 CAMTA1 CRK NPNT FAM76A MGAT4A PER2 FCER1G ELMSAN1 RAP1GDS1 OXSR1 GNAI2 C2orf69 FOXN3 FAM107A FMNL2 BMP3 SHOC2 FOXN2 TMEM251 EEA1 HSPA13 MAPK4 ZNRF3 SMIM20 GPRIN3 RRAS MBP	down	*
MIR96_5P	0.0000492	0.0017664	0.5573322	-0.2526896	-1.468713	378	SLC24A4 AJAP1 EPAS1 COL25A1 NOVA2 SLC12A6 EDNRB TMEM52B ATXN3 RAB3C ST6GALNAC3 RUNDC3B TMEM170B AATK PTPMT1 CAV1 VAT1L QKI CTDSP1 PRKAR1A DENND2C RFTN1 ERG EDEM1 SLC44A2 HBEGF CACNA2D2 RAPGEF4 EIF5 LCP1 CLN5 SLAIN2 PPP3CA ZEB1 TCF7L2 TAPT1 MAP2K3 AGO4 PRDM16 FOXO1 KIAA0513 TRIM46 ZFAND5 SLC7A8 STK17B MYRIP FAM49B DOCK9 SHC4 PTGER3 RNF139 PIK3C2A OXSR1 PAFAH1B1 NUS1 LRRC3 CNOT6L TOPORS MCMBP SPIN1 CREBRF VAMP3 DDHD1 NEK7 APPL1 RAB8B MITF VAT1 SH3BP5 C20orf194 PIK3R1 PCGF5 PRKCE GRB2 FAM43A STX5 GRIA1 RALB NDST1 PPM1F MORF4L1 CD164 PTP4A1 FOXO3 EPHA3 SORT1 AZIN1 ABHD13 FEM1B CBFA2T3 MAP3K2 RELL1 ATXN1 HBP1 PPP3R1 RGS2 NRN1 PCCA ARPP19	down	**
TTTGCAC_MIR19A_MIR19B	0.0000382	0.0014677	0.5573322	-0.2518011	-1.467807	442	WEE1 SLC24A4 SLC31A2 EREG DLC1 KLF13 ADCY9 ARRDC4 CCDC88A DDX6 LONRF1 QKI GPCPD1 BMPR2 S1PR1 C3orf70 TGFBR2 SCARF1 CCNL1 ZEB2 ZBTB4 UBL3 HECW2 RAPGEF4 RAP1A RAB33B SPIRE1 KLF10 FOXP1 CAMTA1 PEX5L MED26 HNRNPU ATP6V1B2 FBXO8 ATP10A RHOB DENND6A SOCS5 SNIP1 RBMS1 ARC PNRC1 LBH CCND2 EPS15 CCSER2 ELK3 ADIPOR2 CLIP4 PRICKLE2 KPNA3 AFF1 NRBF2 BACE1 BTG1 MYLIP CREBRF ID4 VPS37A PKNOX1 PHTF2 SGK1 SOCS3 APPL1 MAGI2 RAB8B CPEB4 ZFP91 PDE5A ATP11A MBNL2 FAM43A KBTBD8 ATL2 TRAK2 EPC2 GRSF1 CALM1 PTP4A1 RUNX3 SRSF6 PPTC7 SLC35F1 TSHZ3 RIN2 FLNC BTBD7 AP1G1 TGIF1 TESK2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 ATXN1 HBP1 WBP2 ANKRD12 NPTN MACF1 PLAA MBNL1 ARPP19 RXRA SYT11 RNF2 MIER1 WDR1 INO80 CEP170 RTN1 EPN2 PARM1 VPS4B BRWD1 G3BP2 KPNA4 RBMS3 RAB2B KIT RNF38 NRP2 C2orf42 ZFPM2 WDFY3 MIER3 DNAJA2 CBX7 ZFYVE26 MB21D2 CLIP1 ZNF800 NR4A2 HIPK1 LNPEP CLOCK TGOLN2 EFNB2 CCNT2 CD69 DNAJB1 GPR137B WDR47 PDE7B ARHGEF12 FNDC3A MEF2D RNF111 B3GALNT2 WDR26 ITGA6 ROBO2	down	**
MIR548P	0.0000102	0.0005669	0.5933255	-0.2448079	-1.466999	504	EREG COL25A1 SWAP70 SGK3 TDRD6 SECISBP2L OSBPL1A GATA2 ZC3H12C CPEB2 BMPER STXBP6 LONRF1 CORO1C THAP2 QKI PRKAR1A KCNN3 CD9 SLCO2A1 OTUD4 LAMP1 ACER3 ZEB2 SH2B3 SPG21 B3GNT5 SLC36A4 SLC7A7 LATS2 PKD2L2 MTF1 REV3L ZBTB21 FOXP1 HIPK3 KLF6 EIF4E PPP3CA JAM3 RB1 PDE4D KDSR AGO4 TBC1D9 SCP2 LIN7C YBX3 HAUS2 THBS1 CEBPA SOCS2 RBMS1 ARHGEF26 CD302 PNRC1 CCND2 ZBTB43 MBD2 PEAK1 KIAA0408 CYP26B1 EFR3A SERTAD2 GPBP1 CREBRF FMNL2 SYNPO2 KIF13A RNF141 RAB8B SLC35E4 ARL5B ARL6IP6 RAB31 DESI2 CNTN4 HSPA1B FOXN2 VPS26A WTAP SKIL MPZL3 PIK3R1 PCGF5 THUMPD1 RC3H1 FSD1L AP3B1 CXCL5 ZNF597 RNF24 OGFRL1 YWHAZ PXK ZNF407 CELF2 AGFG1 RHOQ CTTNBP2 SRSF6 MAPK8 TSHZ3 NAP1L5 VAV3 TMX3 PHF3 SRSF4 METTL14 CCP110 IRS2 CSDE1 TOB1 THAP11 MACF1 PGGT1B ADAM10 KTI12 ATAD2B INO80D HACE1 HELZ JUND MIER1 ABL2 ZNF143 CTTNBP2NL ITPRIPL2 VGF SFT2D1 TIAM1 FBXO30 TOB2 ZDHHC21 SOAT1 KPNA4 ING2 STK4 TTC28 TIMP3 SCAI FNIP2 SNAP29 PRKG1 FGFR1 RORA C2orf42 DUT WDFY3 SPOPL MIS18BP1 EVI5 MAN1C1 ZBTB44 SCLT1 AFTPH SLC16A10	down	***
SMTTTTGT_UNKNOWN	0.0002918	0.0071163	0.4984931	-0.2563284	-1.465312	306	DAB1 ZNF366 GATA2 RCOR1 SLC10A1 DDX6 CITED2 QKI BMPR2 KCNN3 ANAPC15 WBP4 ERG NFIX TRA2B TTL ZNF503 FOXP1 LCP1 SRSF2 LHX6 LRRN4CL CLK1 PDE4D GPM6A GLDN SRSF5 RUNX1T1 USP2 KLF7 SYCP2L ITPK1 CADM1 GPR85 KIRREL3 ID2 USP44 CXXC4 CLK4 DSTN GNAQ ZNF706 VCPKMT PIAS1 FOXN3 SPIN1 WNT9A RYBP SRSF3 CPEB4 DDX17 EPC1 CCR7 SP3 PABPC4 DDX5 STX5 TPP2 OGFRL1 GFPT2 FGFR4 SLC3A2 GPRIN3 PTP4A1 EHD1 TCF4 TGIF1 YTHDF2 ZBTB11 C16orf72 LTBP1 ETS2 MBNL1 ELF5 ARPC2 ZNF143 CTTNBP2NL LMOD1 EPN2 TIAM1 PP2D1 CXCR4 USPL1 TAB2 HNRNPC SIN3A MTUS1 KIF1B NRG1 SFPQ TLK1 SLFN11 EIF4G2 ARHGEF17 DUSP6 NR4A2 FUS SLC38A2 YRDC PTGS1 EBF1 DPF3 MAP4K2 MTSS1	down	**
MIR765	0.0029741	0.0349648	0.4317077	0.3154895	1.465309	219	PRLR PTPRT PCDHGA10 MDM1 XYLB PCDHGA9 PCDHGA5 COL27A1 PCDHGA7 SDK2 GPATCH1 ASIC1 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 CD164L2 PCDHGB6 PCDHGB4 RAD54B PCDHGA11 PCDHGA8 SLC4A8 KAZALD1 LMLN SIPA1L3 RND2 PCDHGA12 PCDHGC5 PCDHGC4 C1orf226 TPCN1 PCDHGA4 PCDHGB7 SDK1 PCDHGA3 ASB16 PML HOXB5 HSPBP1 MYO1A LINGO1 CLMN RUFY4 PCDHGA2 FAM102A DENND1A L3MBTL3 C3orf80 ADAM12 CADM4 FXYD3 ZBTB45 COX10 PCDHGB1 VPS25 ORMDL2 SLC38A7 BTN1A1 RAB15	up	*
TGCACTG_MIR148A_MIR152_MIR148B	0.0005744	0.0114071	0.4772708	-0.2621471	-1.463908	268	PNPLA6 OSBPL11 SIK1 DDX6 QKI AKAP7 GPCPD1 ZCCHC2 S1PR1 ARL8B ELMO1 OTUD4 MOB1B TXNIP BMP1 PTPRM BEST1 HECW2 MTF1 ITGA5 PICALM NLK SLC7A11 ITSN2 GPM6A AGO4 NRARP KLF4 STX3 ITPK1 MGAT4A EPS15 CUL5 PRICKLE2 NCOA1 MMP19 SNN PDK4 TMEM9B SLC25A3 ADCY2 PHACTR2 MTMR14 MITF CPEB4 CNTN4 FBXO11 KLHL18 TRAK2 ITGA11 DEDD NDST1 AGFG1 FOSB PHF3 KIAA0232 RSBN1L SKIDA1 ATXN1 NPTN LTBP1 PLAA ARPP19 RXRA DOCK6 ELF5 MIER1 INO80 EPN2 CYB5R4 UBE2D1 RNF38 MMD LDLR FAM13B NAA15 ZFPM2 USP48 PPP1CB ZFYVE26 STARD13 CDC14A ARHGEF17 CFL2 CLOCK NOG EFNB2 YWHAB SRSF11 C6orf62 UBE2W SCAF11 ARHGEF12 EP300	down	*
RFX1_02	0.0042282	0.0438211	0.4070179	0.3146059	1.462398	217	WFDC3 GRIN2D LYSMD1 ANKFN1 SEMA4B TSHZ2 PTPRR CCDC74A DAW1 AP1S1 LAMP5 RGS6 E2F3 NBR2 CCDC74B MPPED2 OSBPL2 BBS1 SPAG16 QTRT1 TP53BP1 TSGA10 HYDIN CSRNP3 MGAT4B NRSN2 LRRC6 PPM1E CRB2 PICK1 AAGAB E2F1 STX18 REEP6 TCTN2 ITPKA CHCHD3 C3orf67 ANKRD45 SPEF1 THNSL1 DHX40 TSNAXIP1 AARSD1 POLL MORN2 NFATC4 SPTBN2 MAPK10 ZSWIM1 ZNF768 CHD5 KDM3A STRN4 L3MBTL2 STOML2 AP3M2 BAD SH3GLB2 TBC1D16 TMEM17 SCNM1 PAK4 CCDC181 ANK2 TNKS1BP1 NOS1 NLGN2 ENKUR NME7 RHOD CHL1 DCDC1 MOK ANKRD13D TEX9 INO80B DHX57 CASKIN1 DNAAF1	up	*
MIR3942_3P	0.0004289	0.0093578	0.4984931	-0.2603073	-1.460570	275	COL25A1 ZC3H12C ATXN3 ADCY9 NUP54 CAPN14 PLEKHF2 CCDC88A CDH13 EML1 BMPR2 P2RY13 RXFP1 TET2 OTUD4 KCNAB1 CD36 MCTP1 SLC36A4 CSGALNACT2 IFNK DACH1 TMEM38B EVI2B CASP1 RUNX1T1 NPR3 SPAG9 IRAK2 LBH PRDM5 CDC40 INO80C PNO1 PIKFYVE ARL6IP6 NXPE3 TMEM251 PTGER2 DENND4A RALB GAS2L3 SLC25A24 AGPS NECAB1 MAPK8 TSHZ3 PKIA TRAPPC10 KLRC2 XYLT1 AZIN1 NIPA2 VAV3 TMX3 PCDH17 ATXN1 GNB4 ANKRD12 RIMKLB N4BP2L2 ADAM10 SMAD2 ITPRIPL2 SCN7A MGAT2 TPT1 TIAM1 CDKN1C ARIH1 ALDH2 UBE2D1 BRWD1 SCPEP1 BCAT1 NALCN RNF38 DLST KIF1B TRAPPC11	down	**
MIR6882_5P	0.0031151	0.0356518	0.4317077	-0.2822788	-1.460230	142	SMAD6 WEE1 TEK SOWAHC PTPRB EPB41L3 TRIB1 SEMA6D C10orf25 UBE2D3 TIPARP SOCS5 MYO1B MGAT4A UBE2E2 TM9SF2 AKIRIN1 TANC1 EFR3A MYLIP RYBP ETV3 MITF SKIL LSM1 CXCL5 SLC25A24 PTP4A1 GIMAP1 ZNF521 KCNA3 ARPP19 EPB41L5 ARIH1 ISCU TBCEL NFKBIA FAM126B DLST PUM1 SPOPL EIF4G2 DUSP6 MAPK1 ATP1B1 UNC50 RCSD1	down	*
MIR338_5P	0.0000723	0.0024290	0.5384341	-0.2494328	-1.460194	395	GCOM1 CD55 ZC3H12C RAB3C LDB2 DYRK1A KCNN3 NR3C1 CD9 TSHZ1 TET2 ACER3 TMX4 TBX2 ATP2B1 TRA2B PTPRM MTF1 SDE2 PICALM KLF10 PAQR3 CAV2 CAMTA1 FOXJ3 GATA3 SPTBN1 SPRY2 AMOTL1 CCDC82 PPP6R3 GPA33 DAAM2 KLF11 ZFAND5 TMED5 TADA2B JAM2 TLR4 CXXC4 PPP2R5C PPP2R5A KIAA0408 IKZF5 RABGGTB CNOT6L LIN54 USP25 FMNL2 ID4 HESX1 PDHX IL6 SGK1 COPS2 NEK7 PIKFYVE MITF CUL4A ETS1 CNTN4 TBC1D12 FERMT2 SP3 ACKR3 DDX5 PI4K2B CREB1 COBLL1 LSM1 FSD1L LPCAT2 OGFRL1 DENND4A SPRY4 PELI1 KLF2 CDK17 TSHZ3 DAGLA CHORDC1 AZIN1 ZNF521 LSM6 STRN BAZ2B TEC NAB1 MAP3K2 SOD2 HFM1 TOB1 ANKRD12 KAT2B PDE4B MBNL1 MLANA INO80D CCL20 HACE1 ARAP2 RNF138 FGF2 RLF SEC63 ARIH1 TXNDC11 PTCH1 DDX59 POLR2M MBD5 NPAT JMJD1C FAM126B ABCA8 PAIP2 RORA NAA15 C1orf52 TLK1 WDFY3 EID1 FEZ1 BMI1	down	**
MIR3606_3P	0.0003032	0.0072507	0.4984931	-0.2571051	-1.458372	301	SLC6A4 PPARG PTPRB RUNDC3B TMEM170B JPH4 NEDD4L ELF2 RXFP1 WBP4 MOB1B EDEM1 ARHGAP29 CNST ZDHHC2 RANBP9 SPIRE1 SLC7A11 ZBTB8A PPP3CA ZFYVE16 UBE2D3 TMEM38B CYBRD1 PAQR5 ZFAND5 PDE8A PTPRC WASF3 KLRD1 SPRYD7 NUS1 CNOT6L LIN54 TOPORS ELF1 PDIK1L VPS37A SAR1A KIF13A APPL1 RAB8B SERPINB8 ARL6IP6 TBC1D12 EEA1 SP3 CREB1 RC3H1 FSD1L YWHAZ ZCCHC9 RNF146 AGFG1 CDK17 PTP4A1 YTHDF3 AZIN1 PPP2CB STRN NDUFA5 ABHD13 TSC22D1 FEM1B TRGC1 NAB1 TPMT ADAM10 CALB1 HACE1 RNF138 TXNDC11 ALDH6A1 HNRNPK ZDHHC21 RBMS3 MAP3K4 CUL3 RASSF8 TTC28 SCAI PTEN CHCHD7 SNX15 PRKG1 ITCH GSPT1 EIF4A2 HPCAL4 ZNF326 ABI1 KLF15 KALRN	down	**
MIR1250_3P	0.0001063	0.0033897	0.5384341	-0.2473425	-1.455743	427	SLC6A4 FFAR4 SMAD6 GAPT ATXN3 GREM2 LIPA LRRFIP1 PTPRB TTC7B INSIG1 LPL THAP2 QKI GPCPD1 BMPR2 NR3C1 FUCA1 MOB1B RFTN1 SCARA3 SPCS3 ZEB2 ARHGAP29 MYOZ1 B3GNT5 SLC36A4 RAB33B PICALM CAMTA1 SRSF2 LAMTOR3 AKT3 TFRC MYCT1 ATP6V1B2 PTPN21 CCDC82 DGKE KCNMA1 LIMS1 YBX3 MYRIP ATL3 LBH ARL4A DSTN PAFAH1B1 NUS1 TBC1D4 ZDHHC20 FAM102B LACC1 SCEL PDIK1L CREM DNAJC27 PLGLB1 EBF2 EBAG9 CABLES1 RAB8B PDCD6IP TMTC1 HMBOX1 GABPA ADRA1A CNTN4 APBB2 IPO7 SNX2 SKIL CREB1 COBLL1 RC3H1 LPCAT2 ZNRF3 ZNF597 SMIM20 OGFRL1 MOB1A RRN3 RHOQ CALM1 PKIA TRAPPC10 KLRC2 ZFAND6 NIPA2 ATG2B PDS5B VAMP4 FEM1B PDE12 GNAI1 MAP3K2 PCDH17 RIMKLB AMD1 BMP2K RBL2 RNF138 CHURC1 YAF2 FKBP1A TMOD2 EPHA2 ZDHHC21 SRSF10 KPNA4 RBMS3 ING2 BCAT1 SCAI DNAJB9 C21orf91	down	**
MIR7_2_3P	0.0000158	0.0007319	0.5756103	-0.2394062	-1.454532	546	GPR17 TAL1 CPEB2 DPYSL2 RAB3C KCTD9 LRRFIP1 TMEM170B BDNF CCDC88A DDX6 THAP2 SLC39A8 PRKAR1A TGFBR3 EPB41L3 ABCB1 TMX4 RBM7 SLC7A7 BZW1 PICALM EIF4E TOR1AIP1 PPP3CA PLXNA4 TRAF6 NFE2L2 TMEM41B ZFYVE16 PDE4D PDGFA GPM6A GMEB1 CSRNP1 PER3 HNRNPA3 BNIP2 UHRF1BP1L MVB12B MED6 MPL FBXL3 MGAT4A PDE3B NPAS3 CXCL2 AQP4 PNRC1 EPS15 CCSER2 RNF139 WDR48 N4BP2L1 WFS1 PEAK1 MPC1 PRICKLE2 TM9SF2 CYP26B1 BCLAF1 SMNDC1 ACTR2 SIAH1 C2orf69 TOPORS UFM1 SPIN1 TMPRSS11A SCEL CCNY ELF1 SYNPO2 KIF13A EBF2 NEK7 HCFC2 SEC14L1 SF3B1 OXNAD1 CPEB4 PDE5A CCDC50 FOXN2 VPS26A TBC1D12 SKIL EEA1 MBNL2 ATL2 RC3H1 MFAP4 FSD1L GRIA1 SLC10A7 CDK14 AGFG1 SLC25A24 ADNP2 PELI1 PTP4A1 HIVEP2 YTHDF3 AZIN1 CC2D2B TMX3 KIAA0232 PDS5B ABHD13 CNOT7 MAP3K2 PHF19 PPP3R1 GNB4 HINT3 RIMKLB ACYP2 INO80D RNF138 FGF2 PDLIM5 CEP170 HSP90AA1 LRP12 TMOD2 FBXO30 CREBBP RBMS3 STAM2 THRAP3 MCOLN2 PRKG1 CYTH1 PAIP2 CAMSAP2 FAM13C NAA15 ENDOV WDFY3 EID1 MACROD2 RAB2A MIER3 DMXL2 REEP1 KALRN MB21D2 SLC19A2 DCUN1D3 ITGB1 CMPK1 HP1BP3 CCNT2 CTDSPL2 AQR SRSF11 PRTG FPR3 PIAS2 MTSS1 GPR137B EXOC6 RCSD1 GABPB1 STX16 ARHGEF12 ATP8A1 TMEM220 ARHGAP44 SKAP2 MEF2D RNF111 SETD2 ROBO2 SREK1IP1 EDIL3 FNIP1 PTGS2 IMPACT EML5 YOD1 PJA2 PTPRA DCAF13 SCAF8 IREB2 SENP6 CBLL1	down	***
MIR4666A_3P	0.0000183	0.0008135	0.5756103	-0.2436984	-1.451270	476	TRIM71 EREG USP12 ZC3H12C EMP2 RDX PTPRE PID1 KL TMEM170B BDNF TMOD3 HEATR5B QKI BMPR2 HMGCR NR3C1 NEDD9 VAPA WBP4 IL23A TMX4 RAP1A PPP1R15B KLF10 PAQR3 KLF6 CAMTA1 PEX5L DACH1 FOXJ3 PPP3CA ADRB2 AKT3 MCL1 ATP6V1H TLE4 FOXO1 SORBS1 PPP6R3 PPM1K ACSL3 KLF4 ITM2B ROCK1 ZFAND5 ARNTL MGAT4A CADM1 C4orf33 ACTR3 BRF2 MBD2 PPP2R5C EXOSC8 GNAQ KIAA0408 PAFAH1B1 CRIM1 RABGGTB CNOT6L TAF13 ZNF426 MTPN USP25 MOB4 CREBRF ID4 PPP2CA CCNY IL6 ASNSD1 SGK1 NEK7 PIKFYVE PDCD6IP PPP6C UTRN PDE5A OSBPL9 MSRB3 RABGAP1 CSTA WTAP FERMT2 FYTTD1 EEA1 HSPA13 PI4K2B MALT1 MSANTD2 HOMER1 ZNF597 PREX2 DENND4A WDR7 KLF2 HIVEP2 SLC4A5 TSHZ3 DAGLA NAA16 ZNF521 STRN CEP76 TRGC1 PIK3C3 TBRG1 ZNF136 TOB1 RIMKLB ETS2 MBNL1 ARPP19 ARAP2 RNF138 FGF2 PDLIM5 SCN7A NT5C2 ARIH1 PTCH1 DDX59 ZDHHC21 SOAT1 KPNA4 MBD5 LYSMD3 ANKRD49 CEPT1 SCAI B3GNT2 TMEM87A ITCH NRG1 NAA15 ZFPM2 EIF4A2 RAB2A ZBTB44 DMXL2 YTHDC1 ABI1 PSIP1 PLAG1 CLIP1 ZNF800 LIN52 CLOCK MAMDC2 OSGIN2 PDCD2 SH3GLB1 SLC38A2 CEP44 TRPM7 UBE2W SGIP1 PLN AKAP12 SERP1 RAD21 PAXBP1 CUL2 ARHGAP44 FNDC3A SMARCA5 NR5A2 ITGA6 NKTR RAB11FIP2 EDIL3 FNIP1	down	***
MIR3714	0.0000894	0.0028824	0.5384341	-0.2502997	-1.450814	386	SLC31A2 SEMA6A PHACTR1 RDX DPYSL2 MBOAT2 PID1 ARRDC4 RCOR1 RGS9 VAT1L QKI ELMO1 CBL SH2B3 ASAP1 TTL LMNA MTF1 BTG2 ZNF503 ANXA5 LITAF FOXP1 LCP1 SLAIN2 ADRB2 TNS1 EPM2AIP1 SETD3 PTPN12 EFCAB14 AMOTL1 SCP2 DAAM2 ROCK1 ZFAND5 SLC7A8 ADAMTS9 TPP1 MYRIP SPAG9 SNIP1 CDKN1A PIK3C2A CUL5 MPC1 ZNF706 FKBP15 BACE1 TLL1 MTPN USP25 RBM39 MYLIP RBPJ MYO1C CREBRF GZF1 RYBP PHTF2 MITF CCDC3 VAT1 NOTCH1 HMBOX1 HRH1 DESI2 JPH1 BTD CCDC50 CYCS APBB2 FERMT2 PCGF5 MAPK4 SLC10A7 ZNRF3 FAM177A1 THSD7B ACSL1 RHOQ CD164 MBP XYLT1 PEA15 MCUR1 ANKRD12 MACF1 MLANA SMAD2 GLTP MOB3B PDLIM5 MIER1 FKBP1A ELOVL1 DCTN4 SDAD1 ULK2 LYSMD3 KATNA1 LIMCH1 RASSF8 PDE4A ARPC5 MMD ANXA11 TMCC3 NR3C2 IQGAP1 EIF4A2 EVI5 TRIM36 PAPSS2 REEP1 SUGT1 CHP1 CDON	down	**
TATTATA_MIR374	0.0006784	0.0128475	0.4772708	-0.2639547	-1.450208	237	SMAD6 BMPER BMP2 QKI SRSF7 VAMP2 NR3C1 SCN5A CCNL1 ZEB2 NUMB BRINP3 NFIX FOXP1 PAQR3 DACH1 GATA3 SPRY2 PDE4D GPM6A IL10 TLE4 FOXO1 ZCCHC24 ZNF423 MGAT4A PNRC1 CAPZA2 CLIP4 CYP26B1 HES1 AFF1 CRIM1 BACE1 VCPKMT NCOA1 SERTAD2 MOB4 PKNOX1 PIKFYVE CPEB4 CNTN4 DUSP8 SP3 MBNL2 RC3H1 HOMER1 DENND4A PELI1 HIVEP2 YTHDF3 FOSB PKIA C16orf72 ATXN1 MEIS1 LTBP1 ADAM10 PDE4B AMD1 LDLRAD4 FKBP1A SF1 TRAPPC8 MEX3C ZDHHC5 RNF38 ABCA8 CAMSAP2 BANK1 EIF4G2 STARD13 PLAG1 DUSP6 NR4A2 KIAA2026 NOG WNT5A PDE7B RNF214 EP300 DR1 MEF2D SETD2 FNIP1 NR4A3 METRNL NTF3 NFKBIZ	down	*
MIR7_1_3P	0.0000064	0.0004238	0.6105269	-0.2391233	-1.448467	548	GPR17 TAL1 CPEB2 DPYSL2 RAB3C KCTD9 LRRFIP1 TMEM170B BDNF CCDC88A DDX6 THAP2 SLC39A8 PRKAR1A TGFBR3 EPB41L3 ABCB1 TMX4 RBM7 SLC7A7 BZW1 PICALM EIF4E TOR1AIP1 PPP3CA PLXNA4 TRAF6 NFE2L2 TMEM41B ZFYVE16 PDE4D PDGFA GPM6A GMEB1 CSRNP1 PER3 HNRNPA3 BNIP2 UHRF1BP1L MVB12B MED6 MPL FBXL3 MGAT4A PDE3B NPAS3 CXCL2 AQP4 PNRC1 EPS15 CCSER2 RNF139 WDR48 N4BP2L1 WFS1 PEAK1 MPC1 PRICKLE2 TM9SF2 CYP26B1 BCLAF1 SMNDC1 ACTR2 SIAH1 C2orf69 TOPORS UFM1 SPIN1 TMPRSS11A SCEL CCNY ELF1 SYNPO2 KIF13A EBF2 NEK7 HCFC2 SEC14L1 SF3B1 OXNAD1 CPEB4 PDE5A CCDC50 FOXN2 VPS26A TBC1D12 SKIL EEA1 MBNL2 ATL2 RC3H1 MFAP4 FSD1L GRIA1 SLC10A7 CDK14 AGFG1 SLC25A24 ADNP2 PELI1 PTP4A1 HIVEP2 YTHDF3 AZIN1 CC2D2B TMX3 KIAA0232 PDS5B ABHD13 CNOT7 MAP3K2 PHF19 PPP3R1 GNB4 HINT3 RIMKLB ACYP2 INO80D RNF138 FGF2 PDLIM5 CEP170 HSP90AA1 LRP12 TMOD2 FBXO30 CREBBP RBMS3 STAM2 THRAP3 MCOLN2 PRKG1 CYTH1 PAIP2 CAMSAP2 FAM13C NAA15 ENDOV WDFY3 EID1 MACROD2 RAB2A MIER3 DMXL2 REEP1 KALRN MB21D2 SLC19A2 DCUN1D3 ITGB1 CMPK1 HP1BP3 CCNT2 CTDSPL2 AQR SRSF11 PRTG FPR3 PIAS2 MTSS1 GPR137B EXOC6 RCSD1 GABPB1 STX16 ARHGEF12 ATP8A1 TMEM220 ARHGAP44 SKAP2 MEF2D RNF111 SETD2 ROBO2 SREK1IP1 EDIL3 FNIP1 PTGS2 IMPACT EML5 YOD1 PJA2 PTPRA DCAF13 SCAF8 IREB2 SENP6 CBLL1	down	***
MIR4789_5P	0.0001568	0.0044672	0.5188481	-0.2527433	-1.447993	325	WEE1 AJAP1 GPATCH11 TRHDE SECISBP2L HHEX PTPRE BMPER SEC22C QKI PAFAH1B2 NR3C1 TGFBR3 OTUD4 ASAH1 PPP1R15B MAP3K8 HIPK3 SLAIN2 GATA3 ZMYM6 TCF7L2 TFRC RAB14 GPM6A SCP2 PPM1K ZSWIM6 ITM2B NPAS3 NR1D2 PNRC1 UBE2B PIK3C2A SMAD7 INHBA CMTM6 USP25 UFM1 SPIN1 MOB4 FOXN2 TBC1D12 EEA1 PIK3R1 MBNL2 HERC1 GRB2 FAM43A KBTBD8 RC3H1 DENND4A CASZ1 TPRA1 MORF4L1 SPRY4 TSHZ3 BTBD7 STRN PDS5B BAZ2B VAMP4 SBF2 ATP6V1A CNOT7 CD81 EXOC1 TMEM70 TOB1 MAGOH ADAMTS15 CLCN6 INO80D ARAP2 RNF138 TNFAIP8 ZNF143 CTTNBP2NL EPB41L5 ACAP2 TMOD2 CCR9 PSME4 NUP98 LYSMD3 SCAI FAM126B CAMSAP2 FGFR1 SFPQ WDFY3 PUM1 SPOPL ARFGAP3 DNAJA2 PLAG1 CHP1 CDKN1B DKK3 RB1CC1 SLC38A2 EXOC8 EBF1 XRN2 FAM160B1 WAC PLN TSC22D2 RAD21 DDX21 ARHGEF12 SMARCA5 MEF2D CNTN1 PLCB4 SIRT1 HIVEP1 CAPN7 AKAP13 GP5 PTPRA BMPR1A	down	**
MIR196A_1_3P	0.0001582	0.0044715	0.5188481	-0.2524815	-1.447279	328	WEE1 SEMA6A IL1A SLC12A6 DPYSL2 RCOR1 QKI SLC39A8 MTMR10 STX11 DYRK1A CDC42 TGFBR3 NEDD9 CD9 GNPTAB TET2 FAM49A TMX4 HBEGF ARSB PLXNA2 HIPK3 GLS DACH1 MOB3C TMEM123 TFRC TMEM38B TIPARP EPB41L2 EIF1B PER3 AMOTL1 TLE4 LIN7C PLAUR ADAMTS9 PDE3B UBE2E2 CXXC4 CCND2 WASF3 PTGIS MRVI1 ARL6IP5 VAMP3 RNF149 IL6 PDIK1L SYNPO2 SAR1A PHTF2 PHACTR2 NEK7 ARL6IP6 CNTN4 NXPE3 WTAP SKIL PIK3R1 PI4K2B PCGF5 ZNRF3 RGS13 MEAF6 POGLUT1 CDK17 AZI2 NIPAL4 EPPK1 TSHZ3 DGKG NAA16 ING3 PBRM1 HNRNPA2B1 TCF4 NDUFA5 ZBTB1 KHDRBS1 ATXN1 PPIG LEKR1 CRY1 ACYP2 MICU3	down	**
MIR6124	0.0000847	0.0027728	0.5384341	-0.2489466	-1.446957	378	OTUD7A TAL1 PECAM1 ZC3H12C ATXN3 MBOAT2 PTPRB LDB2 NEDD4L BAIAP2 BMPR2 PAFAH1B2 YPEL5 P2RY13 C3orf70 MOB1B DDO ZEB2 SPG21 TACC1 MTF1 SPIRE1 CSGALNACT2 FOXP1 KLF6 GLS CAV2 PAG1 GPBP1L1 DACH1 ZNF365 SETD9 PLEKHM3 KLF11 ZFAND5 NR1D2 C9orf72 PAPSS1 ELK3 PTCHD4 ILDR2 KIAA0408 CRIM1 CNOT6L LIN7A RASGEF1B HGSNAT FOXN3 CREBRF CD80 CREM LRRTM2 COPS2 SLCO2B1 MAGI2 TMTC1 ETS1 OSBPL9 MSRB3 TREM1 FOXN2 APBB2 BAG5 GLIPR1 HUNK CLEC17A IDS CREB1 KBTBD8 RC3H1 MORC3 NAA30 CASZ1 EPC2 ZNF407 CDK14 ESPNL FOS SLC25A24 CDK17 USP7 XYLT1 RIN2 ZNF521 HNRNPA2B1 TSPYL6 RSBN1L TSC22D1 MAP3K2 ATXN1 MYOCD LTBP1 CSNK2A2 IST1 INO80D INTS6 ARPC2 SF1 SFT2D1 NBN MGAT2 BLOC1S2 ARIH1 BRWD1 HNRNPK G3BP2 GRIN3A BCAT1 MAFK PAK2 RORA RHOT1 ELFN1 MAN1C1 IRF2 SCLT1	down	**
CTACTGT_MIR199A	0.0038421	0.0413386	0.4317077	-0.2764699	-1.446705	164	SECISBP2L BMP2 CITED2 CALCRL QKI CDC42 GALNT18 CBL ZBTB4 LIFR C1orf21 BZW1 FOXP1 PTX3 CAMTA1 NFE2L2 AKT3 ZEB1 GPM6A SIK2 ATF3 UXS1 RNF139 ZNF706 AKIRIN1 TANC1 SNN SRF RBM39 PDIK1L RNF141 CPEB4 PI4K2B GFPT2 FOS CDK17 BTBD7 AP1G1 TGIF1 PDS5B BAZ2B APLP2 PHLPP2 MBNL1 RBL2 TAB2 MAP3K4 RAB2B NRP2 NAA15 EHD3 YTHDC1 PLAG1 ZNF654 ATP1B1 CCNT2 ADAMTSL3 CTDSPL2 C6orf62 GOLGA8B	down	*
MIR4773	0.0027287	0.0329480	0.4317077	-0.2771423	-1.445905	158	SEMA6A GCSAML TRHDE HVCN1 ZC3H12C LHCGR HSD17B11 CAV1 CBL SEMA6D ASAP1 CAV2 PLXNA4 PTPRO ANKRD10 TJP1 C11orf91 ITIH5 DPH3 CADM1 AXL KCTD20 LBH ZNF706 RABGGTB FAM102B CELF1 FYTTD1 PRKCE ATL2 CRYM PELI1 AGPS YPEL2 NECAB1 CCR1 ATAD2B SMAD2 AMD1 SIK3 BRWD1 CREBBP CEPT1 TMEM87A DLST KIF1B ZFPM2 ACVR1C OSGIN2 TRMT1L SV2B UBE3A RMDN1 PLN ROBO2 SIRT1 FNIP1 IRF4 KRT10 SKP1	down	*
CIC_TARGET_GENES	0.0006866	0.0129382	0.4772708	0.2961199	1.445624	388	ATP10B MUC13 KIF20A FOXA3 FAM81A FANCI TFAP2A FRK TIMELESS APOLD1 SEMA4B NUDCD3 PHF14 HILPDA KIF14 TTC26 PTTG1 ESPL1 GAPDH AGR2 PLS1 CIB1 GON4L CAND1 XPOT CCT2 UQCC1 KAZALD1 MANSC1 GOLPH3 RPAP1 TP53BP1 KNTC1 WASF1 CLHC1 MSX2 FBF1 CBX3 MYO10 POLD2 MMS22L CDCA5 FANCD2 EMG1 PEX26 ORC6 LRRC61 FBXL19 FADS2 SYMPK EFCAB11 CBX5 ANAPC5 ING4 WDR5B ZMIZ2 FEN1 TNRC18 MTBP SNRPE CENPP RNF44 NET1 TRIM24 NADK2 CNOT2 ARHGAP32 COX7C ITFG2 MAGOHB YARS2 BAZ2A PPHLN1 BRD8 CDC20 ORMDL2 ERBB3 AAAS SIRT4 SRRT KRT8 MRPL24 MCM5 ANKRA2 TDP1 FAM161A EIF3D RTEL1-TNFRSF6B STMN3 LSM4 TCERG1 MCRS1 RN7SL1 GABPB1-AS1 GTF3C2 RTEL1 CDC42BPA TXNL4B MCU ENKUR SNX19 POP4 GLYCTK ZMAT2 TP53 RANBP3 PIGL OAS3 ATF7IP CCDC91 SART3 C12orf10 SETD5 ERLIN1 TEX9 SUMF2 PLAC8 VPS18 WDR55 TMEM259 PEX11A TLN2 ABHD2 TNPO3 MARVELD2 NPM1 PIGS TEFM TRIM59 SEC24C RBM8A PSMD3 STRIP1 INTS9 DHX38 PAN2 KIAA1217 CCDC124 COA6 HNRNPA1 ZNF460 ASB7 HMBS TUFT1 BUB3 HOXA-AS2 WDR93	up	*
CASP8AP2_TARGET_GENES	0.0041080	0.0429325	0.4070179	0.3059121	1.445330	261	FAM227A C1GALT1 ZNF12 C17orf75 PDCD2L ECE2 FABP6 SAYSD1 TIGD1 ASPHD2 LRRC27 LSM5 NME1 TOP3B RANBP1 TMEM41A BZW2 MT-TY EMG1 TARS2 CBY1 COX19 DNAAF3 TRMT2A ALG3 RBAK KNSTRN HPS4 SSBP1 AAGAB WDR31 AP5Z1 ENPP3 ANKRD26 TMEM79 USP42 MTBP TTC16 CCDC57 CENPP WDR24 CHCHD2 ILF2 THNSL1 SMG5 DNAJA3 PSME2 HIRA COPS7B JMJD4 PDRG1 MTND5P11 IQCH ZNF140 LIMA1 VPS25 MRPS23 SNRPD1 UIMC1 SNAP47 RCC1 RNF31 DDX55 KLHL7 NME1-NME2 ZNF195 BBX BMS1 N6AMT1 TRIP4 ENKUR GTF3C5 VPS9D1 AGBL5 TMEM101 CPOX	up	*
MIR5197_5P	0.0036618	0.0398314	0.4317077	-0.2767734	-1.444983	157	IL1A LYVE1 RDX CLDND1 ZBTB34 TXNL1 UBR3 KIAA0355 ADAM17 PCYOX1 LUZP1 GLS MAPK8IP1 FBXO8 UNC45B SORBS1 LIMS1 KLF4 PDE8A ERP44 MGAT4A SEC31A CNOT6L VAMP3 PHACTR2 MAGI2 LRCH1 SHOC2 FOXN2 MAPK4 ATL2 MSANTD2 STRN SKIDA1 ZBTB11 MBNL1 ARPP19 BNIP3L INTS6 EPHA4 ZBTB25 PSME4 SRSF10 MAP3K4 MARC1 SFPQ ANO6 PLAG1 SAP18 ATF2 CLOCK ITGB1 CMPK1 NDFIP1 CTDSPL2 ATP8A1 FNDC3A SKAP2 ATF6 PIGP GJB2	down	*
MIR12136	0.0000004	0.0000538	0.6749629	-0.2294187	-1.442666	839	RTKN2 CXCL3 EREG COL25A1 TAL1 USP12 SECISBP2L RBMS2 GATA2 ZC3H12C CPEB2 DPYSL2 PTPRE RUNDC3B CCDC88A CLEC12B BAG4 LDB2 CAV1 CORO1C NEDD4L INPP5A PAFAH1B2 ARL8B MEF2A KCNN3 VAPA C3orf70 TSHZ1 PSMD5 EOGT ZBTB2 MOB1B PPM1D RCHY1 ABCB1 ACER3 PDCL ZEB2 UBR3 SGMS2 HECW2 ADAM17 LATS2 MTF1 ABCG2 ECHDC1 ZNF503 FOXP1 HIPK3 KLF6 PAG1 SLC7A11 PEX5L PPP2R2A SLAIN2 PPP3CA SRSF2 NFE2L2 SPTBN1 HNRNPU UBE2D3 TXN RAB14 GPM6A SLC7A2 KDSR CPED1 CYBRD1 AGO4 NRARP SGTB BNIP2 ZNF423 PRKD3 ID3 KLF9 ANKRD10 TJP1 STK17B SCAF4 UBQLN1 SSH1 MGAT4A VIM ARHGEF26 ID2 USP44 ACTR3 UBE2B ELMSAN1 MBD2 CUL5 GNAQ TM9SF2 SMNDC1 GNAI2 FAM76B SEC31A TLL1 EFR3A CNOT6L ZDHHC20 FAM102B LIN54 SRF USP25 SERTAD2 RBM39 KANK1 PKIG MOB4 MYLIP RBPJ PPIL4 CREBRF AREG RYBP SAR1A PHTF2 PHACTR2 NEK7 APPL1 PPP6C SLC9B1 NXF1 ARL5B NOTCH1 HMBOX1 KCTD12 ETS1 DESI2 BMP3 TMPRSS11D DUSP8 SKIL EEA1 TTC14 SP3 MBNL2 GPR183 CREB1 LUZP2 ATL2 RC3H1 ATP13A3 HOMER1 AP3B1 TRAK2 OGFRL1 RNF146 SNX9 PTP4A1 YTHDF3 SLC35F1 BTBD7 SAV1 HNRNPA2B1 TMX3 STRN CCP110 ABHD13 YTHDF2 SKIDA1 MCUR1 MAP3K2 RELL1 ATXN1 HNRNPH3 ANKRD13A HFM1 ANKRD12 NPTN CRY1 GNA13 MICU3 KAT2B PDE4B ARPP19 SMAD2 INO80D RNF2 RNF138 PDLIM5 EPB41L5 SCN7A B3GALNT1 ACAP2 CXCR4 CYB5R4 SEC61B ZBTB25 TOB2 UBE2D1 USH2A SSH2 SRSF10 KPNA4 RBMS3 ULK2 TTC32 STAM2 LIMCH1 BCAT1 SIN3A TTC28 SCAI PAK2 FNIP2 SKI TMEM87A FAM126B PRKG1 MMD C21orf91 RORA DOCK4 GRB10 GSPT1 DUT EVI5 MIER3 TRIM36 CACNA2D3 ZBTB44 ELP4 ZNF326 ACVR1C UBR2 SPPL2A NR4A2 HIPK1 SLC19A2 MAPK1 CLOCK MZT1 OSGIN2 ITGB1 SH3GLB1 RB1CC1 SLC38A2 KMT2E EFNB2 PIGK SNW1 CCNT2 DNAJB4 CTDSPL2 EBF1 PPIP5K2 PRTG PPFIA1 TRPM7 UBE2W SPTY2D1 FAM160B1 SGIP1 LDB3 GPR137B ZNF362 BCL10 RAD21 STX16 PCDH15 IRF1 PYROXD1 RCBTB2 FNDC3A KLHDC1 WWTR1 WDR26 SETD2 RC3H2	down	***
E2F1DP1RB_01	0.0040929	0.0429325	0.4070179	0.3152426	1.442408	194	ONECUT1 GRIA4 GABRB3 GPAT2 CDCA7 E2F8 NABP2 CDC6 GAPDH MCM2 CDC25A C19orf57 MCM8 CAND1 EPHB1 CDT1 WDR62 PAQR4 AP4M1 SPTB SEZ6 POLA2 MCM7 CLSPN RRM2 MCM3 LIG1 TOPBP1 DNAJC9 DCTPP1 PKMYT1 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 INTS7 CLTA DNAJC11 RHD POLD1 TYRO3 ATAD5 SASS6 MDGA1 OLFML3 PPP1R8 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 RAD51 ARHGAP11A	up	*
ELF1_Q6	0.0015544	0.0226542	0.4550599	-0.2679539	-1.442046	208	FFAR4 TEK SCIMP RASIP1 KLF13 TIE1 CLEC12A CDH5 MYADM CALCRL ELMO1 KCNAB1 BRINP3 CHMP1B GNGT2 TNIP3 PPP3CA CD37 LIMS1 PSPN VIM TLR4 TM6SF1 FCER1G ALOX5AP ELMSAN1 IL7R PRDM5 CNOT6L PI4K2A ARHGDIB RPL17 MTPN NCKAP1L MYO1C ARL6IP5 S1PR4 C1QA MITF TYROBP SNX2 IRF8 GRB2 STX5 REL TNFSF13 TGFB1 MR1 ARPC2 SF1 ELOVL1 ARRB2 CREBBP OSER1 VSIG10 ABI3 SAMSN1 IQGAP1 PUM1 DNAJA2 FCRL1	down	*
RACCACAR_AML_Q6	0.0015847	0.0227674	0.4550599	-0.2661719	-1.438086	210	GPD1 SLC31A2 SLC12A6 GPR15 PPARG CLDND1 TRPV2 OSCAR MSRA CBL AGPAT4 ZEB2 ERG LIFR SWT1 PICALM CNTD1 HLX GPBP1L1 ZBTB8A ARHGEF2 FLI1 ID3 DAB2 MAFG CCL4 FCER1G EVI2A TBX5 ADAMTS8 IL7R PAFAH1B1 MIR17HG FOXN3 ETF1 RYBP BCAR3 RHOG PIK3R1 REL PDZD2 RASSF2 SRSF4 CD6 CDC37L1 TAGAP DOK2 CCR1 STON1 CRY1 LTBP1 AMD1 SLC43A2 SPIB ZBTB25 NSUN4 SREBF2 JMJD1C SCAI GPR171 FGFR1 FAM13C	down	*
MIR340_5P	0.0000057	0.0003989	0.6105269	-0.2353208	-1.437052	660	SIRPB1 EPAS1 GPR15 DLC1 EDNRB GREB1 SECISBP2L HHEX PTPRE RAB3C RUNDC3B ZBTB34 CAV1 QKI MTMR10 C3orf70 GALNT18 TET2 OTUD4 NFATC3 RHOA CD36 RBM7 UBR3 ATP2B1 LACTB UBL3 SLC36A4 HECW2 ENTPD1 RAP1A ZNF503 REV3L SPIRE1 ZBTB21 PTX3 SLC7A11 JAM3 NFE2L2 TNS1 ZFYVE16 PDE4D HERC3 FBXO8 EVI2B CWC22 PRDM16 NRARP NPNT CASP1 ZSWIM6 TCP11L2 TACR2 PLAUR RUNX1T1 REST RRM2B STK17B MYO1B FBXL3 CLIC4 MYRIP SPAG9 SSH1 ERP44 MGAT4A RBMS1 NR1D2 CTBS ACTR3 PIK3C2A ADIPOR2 TBX5 SLC25A32 CLIP4 CYP26B1 FAM76B NCKAP5 LIN7A ANO2 LIN54 TOPORS SACM1L MTPN USP25 SNX3 MCMBP MYLIP CREBRF PRKRA PRDM11 PDIK1L VPS37A CREM PKNOX1 PHTF2 MED28 PNO1 NEK7 APPL1 PLEKHA3 PDCD6IP UTRN NDNF SF3B1 TMTC1 GABPA JPH1 MSRB3 OSTM1 HELQ FOXN2 IPO7 SKIL DDX5 IDS CREB1 LUZP2 COBLL1 FSD1L ATP13A3 TPP2 THSD7B OGFRL1 BLOC1S6 SLC25A24 CTTNBP2 PELI1 CALM1 PTP4A1 YTHDF3 MYL12A TSHZ3 EPHA3 VAV3 TMX3 ITGA9 NR2C1 ABHD13 ZBTB11 GNAI1 EWSR1 MAP3K2 ATP6V0C CCDC68 HNRNPH3 ADPGK ANKRD12 MAGOH GNA13 MACF1 SPOCK2 POLK PDE4B SMAD2 INO80D LDLRAD4 FGF2 YAF2 SCN7A EPN2 SEC63 ACAP2 TIAM1 LRP12 FBXO30 DIXDC1 UBE2D1 MEGF9 G3BP2 ZNF471 ZDHHC21 NPAT FDX1 CEPT1 KIT C20orf203 CAMSAP2 C21orf91 RORA FAM13B ZFPM2 PUM1 RNH1 TOX2	down	***
MIR106B_5P	0.0000084	0.0005164	0.5933255	-0.2357923	-1.434881	586	WEE1 RAB11FIP1 EREG TMEM100 ABHD5 FGD5 SOWAHC ZC3H12C DPYSL2 ST6GALNAC3 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 C3orf70 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 CRK ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 MSR1 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK SGTB BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 VASP ZADH2 STK17B FBXL3 ATG7 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 CLIP4 PAFAH1B1 KPNA3 NCKAP5 TANC1 CNOT6L CNRIP1 VCPKMT ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 MAPK8 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 TGFB1I1 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 TAGAP KAT2B PHLPP2 PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 UBE2D1 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	***
MIR548AH_5P	0.0006742	0.0128344	0.4772708	-0.2505469	-1.432262	306	EPAS1 SLC31A2 TDRD6 FGD5 CLEC12A RCOR1 CITED2 EML1 SLC39A8 MTMR10 RXFP1 C3orf70 OTUD4 ACER3 TXNIP KCNAB1 CD36 SGMS2 PPP1R15B MTF1 BZW1 BTG2 MS4A14 FZD4 LITAF REV3L PEX5L SLAIN2 FOXJ3 PPP3CA BTG3 FBXL5 TBC1D9 SCP2 REST PRKD3 VASP FBXL3 SPAG9 AQP4 PIK3C2A ELK3 UTP23 PRICKLE2 UBASH3B MARK3 FAM76B ADD1 ACTR2 BTG1 PDK4 TMEM9B MYLIP DNAJC27 PHTF2 DDHD1 DCTN6 PLEKHA3 RAB8B NDNF C2CD2 PDE5A HERC1 FSD1L CXCL5 TMEM128 AGFG1 PKD2 STRN NDUFA5 ZFYVE9 GNAI1 MAP3K2 NBEAL1 ADAM10 PHLPP2 BMP2K PDLIM5 MIER1 LRP12 EPHA4 HSPA8 UBE2D1 ZDHHC21 SSH2 NPAT FNBP4 BCAT1 RNF38 SCAI TMCC3 DOCK4 EIF4A2 ANO6 TRIM36 MED17 ZFYVE26 ZNF800 CLOCK PRKCH ITGB1 YWHAB PTDSS1 CEP44 LAMP3 GPR137B PDE7B TRIM13 RAD21 TES EP300 TYRP1 SMARCA5 B3GALNT2 ZFYVE21 SETD2	down	*
DBP_Q6	0.0045304	0.0461828	0.4070179	-0.2660771	-1.432182	192	SEMA6A ADTRP JPH4 CRY2 TRIB1 ZEB2 ERG LRRFIP2 KIAA0355 TNFRSF8 NFIX PLXNA2 NLK PPP2R2A CD93 ITSN2 GPM6A CNN1 TLE4 ADAMTS9 KLF7 ELMSAN1 DCHS1 AFF3 LIN54 FOXN3 BTG1 EBF2 MITF MN1 DDX17 MBNL2 CDK2AP2 PDZD2 GRIK1 MCAM CD151 SNX9 GPRIN3 TSHZ3 NAP1L5 SFTPC TGIF1 TPMT PCDH17 TOB1 THAP11 MBNL1 UNC13D IL18 ARRB2 SPIB PTCH1 SCUBE1 FAM13C PLAG1 BHLHE41 DUSP6 SPPL2A SVIL ZNF385B	down	*
MIR888_5P	0.0025422	0.0315118	0.4317077	-0.2657959	-1.431739	205	GCSAML TRHDE PRKG2 RAPGEF2 SEC22C CDC42 OTUD4 TRIB1 ZEB2 NUMB EDEM1 RRAGC LATS2 OLFML2A EIF4E ADRB2 TMEM41B TFEC SETD3 CD58 MYO1B ATL3 CYP20A1 CLK4 CAPZA2 N4BP2L1 SLC25A32 KPNA3 LRRC3 AFF1 CNOT6L RASGEF1B MTPN SERTAD2 MED28 GABARAPL2 KIF13A KCTD12 FOXN2 CREB1 RC3H1 YTHDF3 BTBD7 C16orf72 ADAM10 INO80D ARAP2 RLF ARPC2 MGAT2 EPN2 PIP4K2A MEX3C BRWD1 KPNA4 GLUL NHLRC3 PAK2 PAIP2 FEZ1 ZBTB44 RABGEF1 BHLHE41 RB1CC1 FAR1 IFIT5 SV2B CTR9 RCSD1 S1PR5 RAD21 ATP8A1 MAP3K1 RNGTT USP45	down	*
USF_Q6_01	0.0022807	0.0291188	0.4317077	-0.2666287	-1.430273	198	WEE1 SLC31A2 SC5D HMOX1 MCOLN1 SPNS1 RAMP2 BDNF FLVCR2 TET2 LAMP1 HPS5 TRIB1 PICALM EIF4E HNRNPDL LRRN4CL ATP6V1H CSRNP1 TCP11L2 TRIM46 KLF4 SOCS5 UBE2B PER1 GPR157 TLL1 SNN SLC25A33 CREBRF YBX1 SGK1 RAB31 IPO7 EGLN2 DYM CLN3 ADNP2 RHOQ KRTCAP2 HNRNPD EWSR1 HNRNPH3 WBP2 ANKRD12 GNA13 ADAM10 WDR1 VGF DCTN4 SPIB USPL1 RAPGEF3 DUSP7 NR3C2 FAM13B	down	*
MIR186_5P	0.0001263	0.0038634	0.5188481	-0.2399215	-1.425841	474	COL25A1 DLC1 TRHDE PTP4A2 PID1 CGNL1 QKI GPCPD1 TGFBR3 RGPD5 OTUD4 MOB1B ACER3 PKHD1L1 UBR3 MCTP1 SLC36A4 SGMS2 MTF1 CYYR1 ZNF503 SLAIN2 FAM122A NDEL1 ZFYVE16 PDE4D PDGFA TIPARP KDSR C14orf132 FAM124B YBX3 PEG3 PXDC1 RUNX1T1 ZADH2 STK17B KLF7 PDE3B NPAS3 NR1D2 SELL CYP20A1 SHE FRMD4A PTGER3 OXSR1 ZNF706 KIAA0408 SPRYD7 KPNA3 RUFY3 PDE1C AFF1 FAM76B AKIRIN1 LIN7A ACTR2 LIN54 RAB6A SRGAP2C USP25 CREBRF PDIK1L BCAR3 NEK7 TMTC1 MN1 CCDC50 FOXN2 EPC1 DHX15 SNX2 SP3 IRF8 MBNL2 LUZP2 COBLL1 ATL2 RC3H1 FSD1L ZNRF3 DENND4A EPC2 GRIK1 PPM1F MOB1A PLCG2 NECAB1 PKD2 NAA16 SORT1 AZIN1 PDS5B GNAI1 MAP3K2 CNTNAP1 PLSCR4 C8orf37 COL15A1 TOB1 MICU3 CALB1 INO80D RNF2 AMD1 BMP2K ARAP2 RNF138 MOB3B MIER1 ABL2 CHURC1 CEP170 SCN7A EPN2 SEC63 LRP12 VPS4B TRAPPC8 ARIH1 ALDH6A1 PSME4 BCAT1 CEPT1 SCAI PAK2 DUSP7 FAM126B CAMSAP2 PUM1 SLC44A5 RAB2A ANO6 FEZ2 MIER3 MAP4 CHP1 UBR2 CCDC112 NR4A2 HIPK1 MAPK1 RB1CC1 NOG PIK3CG HEY1 PRTG API5 DNAJC8 UBE3A PAX5 ANGPT2 UBE2N SCAF11 TSC22D2 SERP1	down	**
MIR3609	0.0005702	0.0114071	0.4772708	-0.2496980	-1.424782	307	EPAS1 SLC31A2 TDRD6 FGD5 CLEC12A RCOR1 CITED2 EML1 SLC39A8 MTMR10 RXFP1 C3orf70 OTUD4 ACER3 TXNIP KCNAB1 CD36 SGMS2 PPP1R15B MTF1 BZW1 BTG2 FZD4 LITAF REV3L PEX5L SLAIN2 FOXJ3 PPP3CA BTG3 FBXL5 TBC1D9 SCP2 REST PRKD3 VASP FBXL3 SPAG9 AQP4 PIK3C2A ELK3 UTP23 PRICKLE2 UBASH3B MARK3 FAM76B ADD1 ACTR2 BTG1 PDK4 TMEM9B MYLIP DNAJC27 PHTF2 DDHD1 DCTN6 PLEKHA3 RAB8B NDNF C2CD2 PDE5A HERC1 FSD1L CXCL5 TMEM128 AGFG1 PKD2 NAP1L5 STRN NDUFA5 ZFYVE9 GNAI1 MAP3K2 NBEAL1 ADAM10 PHLPP2 BMP2K PDLIM5 MIER1 LRP12 EPHA4 HSPA8 UBE2D1 ZDHHC21 SSH2 NPAT FNBP4 BCAT1 RNF38 SCAI TMCC3 DOCK4 EIF4A2 ANO6 TRIM36 MED17 ZFYVE26 ZNF800 CLOCK PRKCH ITGB1 YWHAB PTDSS1 CEP44 LAMP3 GPR137B PDE7B TRIM13 RAD21 TES EP300 TYRP1 SMARCA5 B3GALNT2 ZFYVE21 SETD2	down	*
AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D	0.0007763	0.0140605	0.4772708	-0.2533089	-1.424195	282	WEE1 RAB11FIP1 EPAS1 EDNRB TAL1 FGD5 KLF13 SIK1 OTUD4 SYNC TXNIP ZBTB4 UBR3 LATS2 PBX3 CAMTA1 LHX6 CRK MCL1 TIPARP TLE4 KCNMA1 NPAS3 CCND2 FRMD4A UBE2B CLIP4 MPC1 CYP26B1 CRIM1 RSRC2 RAB6A BTG1 CREBRF FLT1 DNAJC27 DDHD1 PLEKHA3 PPP6C C2CD2 ZFP91 ARHGEF10 RABGAP1 FBXO11 KLHL18 MBNL2 KBTBD8 RPS6KA1 YWHAZ RASSF2 COL23A1 IP6K1 CELF2 YPEL2 YTHDF3 TSHZ3 SPOP ZBTB11 C16orf72 ATXN1 PPP3R1 HNRNPH3 PHF2 KAT2B PHLPP2 PRDM8 SMAD2 INTS6 INO80 TOB2 EPHA2 FOXJ2 MTUS1 FAM13C DAZAP2 ZFPM2 PURB ANO6 MIER3 TRIM36 DNAJA2 IRF2 ZFYVE26 ARHGEF18 PLAG1 ARHGEF17 CFL2 ZNF800 NR4A2	down	*
MIR3529_3P	0.0000479	0.0017560	0.5573322	-0.2423702	-1.423963	461	EPAS1 GPATCH11 SEMA6A SLC12A6 RDX DPYSL2 SMIM12 RCOR1 ZBTB34 GTF2I SLC39A8 ELF2 MEF2A CDC42 NEDD9 CD9 GNPTAB TET2 EOGT CBL HEG1 TMX4 ARHGAP29 CLCF1 NFIX HBEGF FOXA2 RANBP9 KLF10 FOXP1 DACH1 GATA3 TRAF6 ARHGEF2 TMEM38B NBPF12 EPB41L2 GMEB1 EIF1B AMOTL1 TLE4 SGTB KCNMA1 SORBS1 LIN7C PRKD3 ANKRD10 EPM2A ST7L UBE2E2 CCND2 WASF3 SLC25A32 GNAQ RBM44 PDE1C CRIM1 KREMEN1 SIAH1 UFM1 GPBP1 DCP1A FLT1 PDIK1L PHTF2 PLGLB1 PHACTR2 APPL1 PNMA2 KCTD12 DESI2 CELF1 CNTN4 NXPE3 MTMR9 WTAP ELOVL7 SP3 MBNL2 ZNF804A ATL2 FSD1L SLC10A7 ZNRF3 SUCNR1 PREX2 OGFRL1 CELF2 TMEM192 CDK17 YTHDF3 CCDC85A EPPK1 SLC4A5 ING3 CHORDC1 NUP153 PBRM1 HNRNPA2B1 AP1G1 SKIDA1 ATP6V1A KHDRBS1 ATXN1 COL15A1 GNB4 CLASP2 GNA13 ACYP2 N4BP2L2 CCL20 GLTP EPB41L5 PUS10 IER5 PARM1 LRP12 ARIH1 ALDH6A1 TBC1D1 SP100 HAVCR2 ISCU RBMS3 MAP3K4 LYSMD3 CUL3 SCAI ST6GAL2 DNAJB9	down	**
HOXA1_TARGET_GENES	0.0000140	0.0006807	0.5933255	0.2786542	1.422603	959	SYT8 STYK1 FAM24B IGSF9 KCNK5 DNAH2 CCDC127 PAIP1 PDCD2L SEMA4B NDC80 MKS1 SRGAP3 TBRG4 BET1 THEM4 CREB3L4 METTL1 GINS1 CDCA2 IFT122 ANLN SNF8 ANKRD24 FLAD1 IFT27 CDCA8 ALDH18A1 ESPL1 FIGNL1 SPATS2 PMS2 CKLF-CMTM1 EIF3B MIS18A KIAA0895 ZNF3 DZANK1 LRRC27 CCT2 LSM5 FAM220A HAUS5 RANBP1 ASAH2B RUVBL2 CCDC150 CISD1 XPNPEP3 NOP9 SDHA BOD1 F2RL1 TP53BP1 PCCB FBXW9 FRS2 MAP3K13 IQCD NUP155 MYO10 C1orf226 ZNF174 CENPW TPCN1 NSUN2 SETDB1 ZNHIT6 KLHDC4 FANCD2 LINC00857 TRPT1 LMNB1 SEC61A1 AIMP2 EMG1 PYCR2 TARS2 WDR60 BCL2L2-PABPN1 SPINT1 C7orf50 IFT172 TRMT61B CENPO COX19 EHHADH DCTPP1 XRCC1 PIH1D1 TRMT2A RAD18 FDXR MTG1 PHB ERCC2 PIGO SPRY1 SRRM5 UQCR11 RECQL5 CKLF RNF216 CKS1B MRPL36 CDKN2C HARS2 ING4 PABPN1 HDGF WDR5B DNAH6 CENPJ CENPH AP3D1 PICK1 PHF12 ADAP1 NBPF3 GTF2E1 ACP6 SMG9 CMTR1 PRPF6 AP5Z1 KIF2A SDCBP2 ENPP3 ZNF584 ANKRD26 LARP1 CPNE1 TMEM79 TNPO2 FADD METTL3 ATAD3A TTC16 CBX1 SRD5A1 UBN2 ZNF692 RANGAP1 CHCHD3 LGR5 PARS2 MZT2B DENND6B SPEF1 ILF2 DCAKD SMG5 COA3 SLC26A2 ADNP PUS1 ADAT1 ZNF133 MAN1B1 MBD4 MRPS34 S100A16 LONP1 PIGG GPRC5C CCDC130 COX7C FBXO4 CENPQ AGPAT5 DAP3 KRBA2 GFM2 TM9SF4 CKMT2-AS1 CDK13 C12orf73 MAGOHB PARP9 CCT7 CDC7 KLC4 CLDN12 SUPT16H DHRS1 PFAS CPSF4 TMEM106B NPRL3 GBF1 MAN2A1 FAF1 LRRC59 GPATCH4 ASCC1 ACLY ZNF497 MRPL24 MCM6 MYPOP KDM4B CENPT NOB1 RPPH1 KPTN WDR35 ANKRA2 MALSU1 LTV1 HAX1 C1orf109 ZSCAN32 TMUB1 NEURL4 POLR2I CYP4F12 MED27 SF3A2 DDX55 GOSR2 TSR1 DUS2 SPSB3 GTPBP10 KLHL7 ZNF580 NDUFV1 MICAL3 RRNAD1 NCDN SMARCA4 RBM42 RN7SL1 HDLBP ZNF169 DTX3L DENR CDK5RAP1 ABCF2 ABHD10 UQCRC1 AP001372.2 INO80E NUBP2 N6AMT1 TTC1 TRIP4 BRMS1 COPA ZNF217 SUPT3H SAMD4B KIAA0825 TCF25 ACP1 SNX8 CTTN NUBPL TBCB ALDH3A1 SIRT6 RPN1 XPC DNAJC14 ADRM1 POP4 SMPD4 NDOR1 GGCX NMT1 TIMM44 RANBP3 MRPS27 TBL3 UBE2C DCDC1 MSRB1 RFT1 ENO1 SLC39A1 NAT10 TK2 TTLL5 TRUB2 FAM222B SCAF1 ATG4B COX17 CALU MOK MTG2 FTSJ3 FBXL18 ERCC3 ALKBH2 PARP2 HEXIM2 VPS18 MORN4 USP20 DHDDS MROH7 MLH3 MAN2C1 METTL4 SH3RF2 FAF2 EIF2B1 CDK11B ADSL NUDT22 SRI HUWE1 ROPN1L RAB11FIP3 ATRIP OPA1 SAFB MRPL2 SLC4A1AP STARD10 GLRX5 LINC00271 TYK2 NPM1 GCC1 PRCC ZNF425 RPS6KB2 GAK ARFIP2 SAFB2 TMEM214 CXXC1 SLC27A5 ZNF805 CACTIN MAP3K5 WDR89 CCDC86 NAE1 PLEKHJ1 SIX5 TTC13 TMEM175 THAP4 C1orf74 ARL1 SRSF9 REEP4 STEAP2	up	***
E2F2_TARGET_GENES	0.0000018	0.0001708	0.6435518	0.2771556	1.421798	1186	ATP10B COL17A1 PRR15 SYT8 PTPRZ1 DDX11 FAM227A KIF20A DDX12P CDH17 HJURP PKP2 TICRR MCM10 RPGRIP1L BUB1B CCNB1 CENPF IGF2BP3 APOLD1 DDX11-AS1 SEMA4B TTF2 PHF14 PLEKHA6 METTL1 TMC1 GINS1 C6orf141 EFNA3 NOL12 STK31 PCLO EIF2B5 COL7A1 FLAD1 TTC26 NUF2 AURKB CENPA CDC6 TPX2 MCM4 LSR XPNPEP1 FERMT1 NWD1 EIF3B DTL GON4L MCM8 LIPE-AS1 NCAPD2 AVL9 MYL6B CDK5RAP3 AOC1 UQCC1 LSM5 KCNG3 KAZALD1 TJP3 MANSC1 ASAH2B POLR3A ZSCAN2 BZW2 LTB4R2 NUDT1 C19orf48 RPAP1 ZFYVE27 SPAG16 KIF15 AP4M1 KNTC1 FRS2 TIGD4 BRAT1 TOP2A RFXANK EME1 SAE1 ATR GTPBP3 SMARCAL1 MCM7 E2F2 POC1A CLSPN WDR78 ABCC5 RGL1 LIPE MMS22L PRKDC RAD54L MRPL27 KIF11 FANCD2 LINC00511 CCDC58 EMG1 ZNF785 MYRFL RNFT2 WDR60 BRI3BP TOPBP1 ARHGEF38 CBY1 DNAAF3 SPC24 AKT2 C6orf223 FDXR GRHL2 PHB COMMD4 FADS2 NAA40 C2CD3 SRRM5 UQCR11 PPP1R37 MYO1A INCENP EFCAB11 NCAPG2 CDKN2C MEA1 SUPT5H ASF1B MRPL37 C2orf50 CDK1 PABPN1 HDGF CDK12 SSBP1 PPIC CEP97 MCTP2 EXOSC2 RFWD3 WDR54 PHF12 ZSCAN25 AAGAB SUN1 LINC00894 REEP6 ZNF815P CCNJL MRPL17 PRR14L ENPP3 ZNF584 TMEM79 TNPO2 POC1B LINC00649 TTI1 ATAD3A UQCC2 HMGXB3 DIAPH3 VPS72 TSPAN1 CENPP C9orf43 IFT52 KPNB1 CHCHD3 TPD52L2 RNF44 DHX34 POLR2H MYO19 ZSCAN9 ZNF687 PARS2 CEP63 CAPS2 INTS7 EDEM3 DPP3 CDC23 DCLRE1C SATB2 SMG5 SEC16B MTOR ZNF133 SNRPA FHIT UROS LONP1 ARHGAP32 CCDC151 PKP3 GPRC5C MRPL11 IQCG PPOX PLEKHA8 ENAH PCSK4 NFATC4 CASP7 CENPQ RHBDD3 MLEC SLC22A5 IQCK ANP32E TCEA1 GFM2 C15orf41 IQCH FKBP14 CDK13 SIL1 C12orf73 NUP85 CEP128 PRRG2 CCDC159 PPME1 ENC1 ELAC2 CDC7 IP6K2 YARS2 NIF3L1 SLX4IP NR6A1 CENPK CLDN12 KLHDC3 SH2B1 TADA3 EFCAB7 LIMA1 CKAP5 BRD8 RPRD1B AHCYL1 WDR34 RIN1 EFHC1 FAF1 GPATCH4 POP7 PPP6R1 CDK5RAP2 KRT8 MCM6 ZNF320 MGME1 KDM4B PLEK2 STAMBP METTL2B PPCDC CYP2S1 UBL7-AS1 LPCAT4 CENPT CKAP2 NSUN6 NOSIP MCM5 CD2BP2 TDP1 SLC35A3 SRSF1 GINS3 LRCH4 HOXA-AS3 AATF PRSS16 DUS4L MRPL51 ETV6 SUGP1 SH3BP5L ANK3 SF3A2 STK35 ATAD2 GOSR2 U2AF2 EPCAM GNAL KLHL7 LRRC14 AP2S1 SH3D21 MICAL3 AMN1 GLO1 B9D1 RPS26 RRNAD1 MSH2 MAP3K14 CCNA2 NCDN PRR11 BANF1 CAP2 GTF3C2 SNRPD2 DOHH NAV1 PAK4 CCDC9 ABHD10 VPS33B OSBPL10 TTC1 TRAPPC9 ZNF384 TRIP4 PFKM ARHGAP5 KIAA0825 SNRNP200 SNX8 TBC1D32 NUBPL CPOX UBAP2L ATG2A SMC2 BCAS3 POLR1B BCL6 TMEM260 MAU2 CENPE TCF3 ANKMY2 SRCAP	up	***
MIR4492	0.0025618	0.0315449	0.4317077	0.2943594	1.418480	338	SLC9A3 PPM1H PCDHGA10 CPLX2 PKP2 ARMC3 PCDHGA9 JPH3 PCDHGA5 PCDHGA7 SDK2 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 CUEDC1 PCDHGB4 PCDHGA11 PCDHGA8 TNC SYT12 OSBP2 TMEM41A STRA6 PAQR4 PCDHGA12 BRAT1 PCDHGC5 PCDHGC4 ZNF594 PCDHGA4 PCDHGB7 SDK1 PKM PCDHGA3 SMYD5 PLXNA1 ZNF618 CLIP3 HES6 EEFSEC PML TMEM178B TTYH3 MGLL ZNF346 PPIL2 IGFBP5 PACS1 FBXO41 RUFY4 LARP1 GPRIN1 RAB6B PCDHGA2 CENPP ARNT2 ACVR1B SRD5A1 RNF44 ZNF454 NMNAT2 FOXK1 COL1A1 ALX4 NDUFA11 NFASC NGFR EPHB2 DNM1 COPS7B TJAP1 MAP6D1 CHD5 SLC1A3 PPME1 COX10 PCDHGB1 MDGA1 CADM3 ASB6 KCNIP3 NAT8L KIF21B CABP7 TBC1D16 EDAR TTLL6 VWA3A SH3PXD2B STRBP CEP85 CAPN15 ENGASE APC2 DDX54 PAK4 ABCF2 ACSF3 TRAPPC9 SAMD4B TYSND1 SNX19 PTPRF MAPK8IP3 TRIM62 NPTX1	up	*
ZNF250_TARGET_GENES	0.0007430	0.0135882	0.4772708	0.2870787	1.417547	486	HMGA2 COL17A1 PKP2 RUVBL1 SPINK13 BUB1B DOC2A C17orf75 SEMA4B NUDCD3 RGMB-AS1 MRPL46 ANKZF1 FLAD1 TTC26 CEP70 NUF2 ACY1 GINS4 NCAPD2 ZWINT CCT2 NME1 WDR62 C5orf34 BZW2 TMEM184A RFXANK EME1 IQCD GTPBP3 MAD1L1 COASY TPCN1 RBM28 MRPL3 MRPL27 TARS2 LETMD1 WDR60 NME5 EME2 ACTL6A SCAMP5 GAS8 PIH1D1 THAP10 MRPS11 CAPN8 NUSAP1 HARS2 SUPT5H KRT18 ANAPC5 PABPN1 SSBP1 PHF12 ADAP1 STX18 TRIM41 ENPP3 CYCSP10 ATAD3A GOLGA5 NOP2 WDR24 ZNF692 FANCG RN7SL449P VIPAS39 SLC26A2 JOSD2 ZNF133 MRPS34 LONP1 MORN2 MLEC MTND5P11 ITFG2 STX18-AS1 TEKT3 DNAJC11 DNMBP CKMT2-AS1 C12orf73 PRRG2 ZBTB45 SLC1A3 COPS6 SH2B1 TADA3 EFCAB7 LIMA1 VPS25 ORMDL2 FBXO22 KRT8 METTL2B ZNF446 NOSIP KPTN SNRPD1 SLC35A3 RTEL1-TNFRSF6B LRCH4 STMN3 NDUFS7 MRPL51 RGMB SLC41A3 TCERG1 SPSB3 MICAL3 NME1-NME2 PRPF18 RPS26 NFRKB DBNL RTEL1 DENR RFC5 STAT6 CDK5RAP1 PRPF31 VPS33B NUBP2 BMS1 ZNF384 TRIP4 FBXW11 SNRNP200 BCAS3 BCL6 GOSR1 ZSCAN29 ANKMY2 ZMAT2 LRSAM1 GDPGP1 FIS1 PPIA RAD1 MRPL48 ATF7IP TRUB2 SART3 HEMK1 BRIX1 ZNF562 DNMBP-AS1 COPE INO80B DHX57 ANO8 NOXA1 ZC3HC1 HUWE1 OPA1 NSL1 EEF1A1P32 ZNF774 MAD2L1BP LZTS2 NPM1 TEFM RPLP0 PCBP4 CS TIPIN MTF2 TXN2 LRPPRC FAM149B1 MCCC1 PPP2R1A BNIP1 TMEM102 DDX49 SLC44A1 SLC12A9 TUBGCP5 EBNA1BP2 COQ4 ZNF302 OIP5 COA6 MPLKIP ABCB8 WBP1 KLHL20 KHSRP HOXA-AS2	up	*
MIR4719	0.0001321	0.0039660	0.5188481	-0.2409934	-1.417484	423	WEE1 AKAP5 TAL1 CPEB2 P2RY1 NUP54 RCOR1 ZBTB34 LONRF1 THAP2 FLVCR2 NR3C1 VAPA IL1RN OTUD4 MOB1B CD36 KIAA0355 PTPRM ADAM17 LIFR PPP1R15B CLEC7A GLS PRSS12 PPP2R2A NR4A1 MED26 TCF7L2 GPM6A CCNI RHOB ZMIZ1 UNC45B CWC22 RAB12 PTPN21 FOXO1 HNRNPA3 DENND6A PIP5K1B FAM76A REST TJP1 ZNF24 FBXL3 KIF26A CDKN1A EPGN CDS2 ZBTB43 PLEKHB2 PER1 MBD2 TBX5 RBM44 SPRYD7 BCLAF1 PDE1C IL24 CRIM1 NCKAP5 TANC1 CNOT6L NCOA1 FOXN3 LACC1 SPIN1 FRY METAP1 PHACTR2 MAGI2 PNMA2 GABPA ATP6V0B JUNB MTMR9 EEA1 HSPA13 IDS CREB1 LUZP2 ATL2 RC3H1 FSD1L OGFRL1 PALMD AGFG1 SPRY4 CDK17 HNRNPD SPOP AZIN1 GOLGA8R ABHD13 VAMP4 TSC22D1 PCDH17 PPP3R1 POLK FAM98B SMAD2 INO80D HACE1 PITPNA RBL2 NBN DCTN4 CYB5R4 DIXDC1 CREBBP KPNA4 GLUL RASSF8 RET TTC28 MARC1 DOCK10 FAM126B KIF1B CAMSAP2 SLC22A3 NABP1 C1orf115 SLC35A1 ZBTB44 SLC16A10 ABI1 REEP1 KLF15	down	**
CEBPDELTA_Q6	0.0028996	0.0346641	0.4317077	-0.2642227	-1.415513	184	GPD1 DAB1 ACE FABP4 BDNF PDE1B CITED2 CDC42 IL1RN TRIB1 IL23A CCNL1 ZEB2 SEMA6D FOXA2 ITGA5 FOXP1 SLC7A11 NR4A1 LHX6 FLI1 MAP2K3 PTGIR ZNF423 ZADH2 UBE2E2 GPR85 ATF3 CCND2 ELMSAN1 RBM39 VAMP3 COPS2 C2CD2 JUN MITF NOTCH1 PIK3R1 MBNL2 OSM FOS FOXO3 FOSB TSHZ3 DOK3 ZFYVE9 MBNL1 PRDM8 SYT11 UNC13D SPIB ARIH1 PTCH1 SREBF2 TIMP3 PTEN RORA	down	*
MIR95_5P	0.0000449	0.0016762	0.5573322	-0.2343137	-1.414010	569	SLC24A4 SEMA6A CD300LF SLC12A6 TBX3 ZC3H12C CPEB2 WNT4 P2RY1 GPR65 KCTD9 TMEM170B BDNF KLHL8 GFOD1 CALCRL QKI GPCPD1 INPP5A PAFAH1B2 IDI1 CIR1 NR3C1 MOB1B TMX4 EIF4A1 NCEH1 CARD16 ADAM17 LATS2 SDE2 ZBTB21 CAV2 FOXJ3 PPP3CA SPTBN1 TFEC ZEB1 SRGN ARHGEF2 PDE4D HERC3 MYCT1 GPM6A FBXL5 SNAI1 SGTB PTPRO SLC12A4 COQ10B REST ADAMTS9 TMED5 SOCS5 ZNF24 NPR3 CXCL2 C9orf72 PTGER3 UBE2B CCSER2 RNF139 RPF1 MBD2 TBX5 CLIP4 GNAQ NUS1 TP53BP2 MAFF RSRC2 TGFB2 HEXB SRF PPIL4 RYBP PDIK1L VPS37A SGK1 MAGI2 PIKFYVE PDCD6IP PPP6C SEC14L1 HECA NOTCH1 RAC2 ATP6V0B CCDC50 PLK3 JUNB FOXN2 EPC1 DHX15 SKIL MPZL3 SP3 PABPC4 PSTPIP2 PRKCE IDS ATL2 MORC3 FSD1L NOL7 WDR7 OCIAD1 BLOC1S6 GPRIN3 RRN3 BCL6B CDK17 CD164 YTHDF3 USP7 EHD2 PPP2CB SAV1 AKIRIN2 TMX3 ISM1 DCAF5 ABHD13 ATP6V1A FSIP1 PCDH17 ATXN1 C8orf37 KCNA3 TAGAP ANKRD12 STX12 CLASP2 FAM180A SMAD2 INO80D ICAM1 CCDC69 CXCR4 DIXDC1 TXNDC11 ZDHHC21 PARVA MBD5 COMMD8 CUL3 RASSF8 TTC28 MAFK CTSC RNF38	down	**
ZNF784_TARGET_GENES	0.0022213	0.0287339	0.4317077	0.2871286	1.413533	442	LYSMD1 BUB1B NUP107 C17orf75 PGM2L1 DDIT4 THEM4 TTC26 PLK1 NUF2 WDR70 ZNF221 CIB1 AGK NME1 AARS2 TOP3B TJP3 TMEM41A ZNF391 BBS1 RNF216P1 PAFAH1B3 CCDC77 NUP155 CBX3 PSENEN GTPBP3 COASY ABCC5 RBM28 TARS2 EME2 THAP10 GEMIN7 SPAG8 PML MNAT1 ZCRB1 DDX51 SUPT5H ANAPC5 ING4 HDGF SSBP1 STX18 MCAT WDR31 DHX33 ENPP3 ZNF775 TMEM79 RNF207 KLHL22 WDR24 CAPS2 SMG5 ZNF233 GALK2 PCAT6 MRPS34 HIRA COPS7B STOML1 CASP7 JMJD4 MLEC MTND5P11 STX18-AS1 NDUFA13 GFM2 ZNF282 SIL1 FAM207A PRRG2 ZBTB45 NIF3L1 PROX1 EFCAB7 LSG1 RAI1 PPHLN1 VPS25 SIRT4 DUS1L ASCC1 MRPS23 PPP6R1 WDR83 NSUN6 NOSIP NOC4L KPTN NMNAT1 SNAP47 GINS3 NDUFS7 YIPF2 DDX55 PRMT5 ZNF580 MICAL3 NME1-NME2 TSPAN10 RBM42 BANF1 ELFN2 POLR3B SCNM1 CDK5RAP1 BMS1 TRIP4 ZFP14 PPFIA3 PFKM MARK4 GTF3C5 SRP9 VPS9D1 AGBL5 TMEM101 AURKAIP1 ZNF131 DNAJC10 TP53 BPNT1 TBL3 PIGL FAM185A MRPL48 ATF7IP ZER1 TRUB2 DDX41 MZF1 SETD5 SLC33A1 HEXIM2 ANO8 MRPS16 ASB16-AS1 MAN2C1 TMEM259 RPL36 NOXA1 ZNF276 ZNF688 ZNF579 PRPSAP2 NSL1 EDC4 SNHG17 MCEE SLC4A1AP RAG1 TEFM	up	*
MIR369_3P	0.0015497	0.0226542	0.4550599	-0.2532976	-1.411545	257	SMAD6 GCOM1 BMP2 KL IDI1 DYRK1A WBP4 SCN5A PLXNA2 RANBP9 PAQR3 SLC7A11 SRSF2 ZEB1 PDE4D PTPN12 TBC1D9 CCL22 TLE4 PTPN21 FOXO1 TBX4 BNIP2 ZSWIM6 ZNF423 TJP1 CEBPA KLF7 FBXL3 MGAT4A LRRC40 PNRC1 CAPZA2 GCA HES1 BACE1 LIN7A RBPJ PRDM11 RYBP PHACTR2 HSD17B13 C11orf58 FOXN2 ELOVL7 SP3 MBNL2 RC3H1 HOMER1 PREX2 DENND4A GRIK1 OCIAD1 PELI1 YTHDF3 ZNF521 VAV3 TCF4 NDUFA5 MAP3K2 C8orf37 TAGAP RIMKLB LTBP1 ADAM10 PDE4B YAF2 TRAPPC8 POLR2M FNBP4 RASSF8 JMJD1C RNF38 SKI PDE8B MMD RORA SHISA6 UBAP1 EGR1 CFL2 GJC1 ATF2 UBA6 USP30 MZT1 TBC1D23 PIGK UBE3A PLN CAPZA1 SGPP1 RNF214 EP300 DR1 RAB39A SETD2 RC3H2 RAB11FIP2 FNIP1 SEMA5A PEX13	down	*
MIR3140_3P	0.0043930	0.0449050	0.4070179	-0.2621563	-1.410022	187	SEMA6A OSBPL1A CD55 SLC16A12 KL BMPR2 DYRK1A NR3C1 WWC2 WNT2B CHMP1B C1orf21 COL4A2-AS2 CAV2 PEX5L JAM3 AKT3 TCF7L2 ZMIZ1 CYBRD1 ZSWIM6 ACSL3 FMO2 AQP4 SLC6A6 PRDM5 PDE1C C2orf69 SNX3 RBPJ CREBRF VPS37A MAGI2 PI4K2B RGS13 APOL4 SLC35F1 CR1 MME GLRA3 FEM1B CDC37L1 KHDRBS1 CBFA2T3 MAP3K2 PCDH17 INTS6 TAB2 RBMS3 FNIP2 CAMSAP2 C21orf91 NRG1 ZFPM2 PURB MIER3 AFTPH	down	*
MIR27A_3P_MIR27B_3P	0.0000671	0.0022980	0.5384341	-0.2349413	-1.409307	528	PRMT8 SLC24A4 RAB11FIP1 SEMA6A STAC MS4A7 ENDOU PPARG GATA2 SNX10 RAPGEF2 ST6GALNAC3 SIK1 CDH5 ARRDC4 ZBTB34 TMEM170B ST3GAL6 KIAA1109 LONRF1 QKI HMGCR DYRK1A KCNN3 NR3C1 TGFBR3 RGPD5 HEG1 ERG SEMA6D ATP2B1 HBEGF BEST1 LIFR ASAH1 ITGA5 BTG2 FZD4 LITAF CAMTA1 SLC7A11 ABHD6 GATA3 SFRP1 SPRY2 ITSN2 SOX7 SLC7A2 TAPT1 NRARP FOXO1 BNIP2 ZCCHC24 CDIP1 SSH1 MGAT4A PDE3B NPAS3 NR1D2 ARHGEF26 SHC4 SHE PTGER3 RNF139 PEAK1 KPNA3 RUFY3 NRBF2 FAM76B AKIRIN1 SNN ZNF426 BTG1 USP25 PDK4 TMEM9B CREBRF DCP1A SLC25A25 ID4 PDHX CCNY RYBP DNAJC27 PSEN1 RNF141 SLC9B1 NXF1 NECAP1 C2CD2 PSMA1 C20orf194 HIC1 C11orf58 BMP3 DDX5 GRB2 CREB1 KBTBD8 RC3H1 HSD17B12 TSPYL1 GFPT2 CELF2 AGFG1 POGLUT1 NIPAL4 NECAB1 FOXO3 SLC35F1 FOSB PKIA AKIRIN2 VAV3 PDS5B RSBN1L SBF2 SLC24A1 NPTN GATA6 KAT2B TMA7 PHLPP2 ATAD2B INO80D AMD1 GEM GLTP ABL2 CDC42EP3 TRAPPC8 PTCH1 VSIG10 MAP3K4 LYSMD3 MARC1 RNF38 SCAI EPB41L4A CECR2 TLK2 PRKG1 MMD PAIP2 NRP2 C1orf52 NABP1 LPAR6 GSPT1 SMAD4 MIER3 CACNA2D3 HSDL1 SPATA13 FCRL1	down	**
CEBPZ_TARGET_GENES	0.0000035	0.0002735	0.6272567	0.2741321	1.409169	1249	ONECUT2 MDM1 RUVBL1 CEP89 TICRR FANCI ZNF273 TROAP NUP107 DROSHA POLQ GGCT TTF2 IFI27L1 RGMB-AS1 BRCA1 CREB3L4 ZNF138 MRPL46 CDCA2 AGFG2 ANKZF1 TRAIP NABP2 FLAD1 TTC26 SAP30L-AS1 DGCR8 NUF2 IFT27 CDCA8 CENPA ACOT8 GOLGB1 CDC25A UMPS PMS2 CCNF TDRKH MIS18A LIPE-AS1 DZANK1 CDK5RAP3 LRRC27 TRIM45 LSM5 ZNF726 FAM220A NME1 GOLPH3L TOP3B C5orf34 RUVBL2 TMEM41A NEURL2 RAB11B-AS1 OSBPL2 CHAF1A DCBLD2 HLTF EMC9 TP53BP1 POLM COPG2 TOP2A AURKA IQCD ZNF587B ITGB4 ATR POLD2 GTPBP3 ZNF174 RSRC1 C14orf93 TPCN1 RBM28 BRPF3 RAD54L MRPL3 FANCD2 MCM3 CDC25C AIMP2 EMG1 PYCR2 TARS2 RNFT2 WDR60 CHD6 SARS2 ZNF443 MORC2 C7orf50 ORC6 ACTL6A CKAP2L TRMT61B COX19 DCTPP1 DNAAF3 ANKRD16 SPC24 MRPS11 B4GALT7 BRIP1 RAD18 SNAPC4 BLM LRRC45 CNOT3 ARL16 ERCC2 RECQL5 DDX56 INCENP CKS1B ISOC2 FRMD5 CBX5 ASF1B MRPL37 ANAPC5 PABPN1 HDGF SSBP1 CCDC61 KCTD7 MDH1B RFWD3 ZNF652 AP3D1 NUDT2 ANKRD54 TYW1 POLR3K E2F1 UNG STX18 VPS28 ZNF419 MCAT PMEL BPGM FAM98C ENPP3 ZNF584 NARF DPH7 TSPAN31 ZNF775 COA4 MRPS12 LCA5 FAM102A DIAPH3 VPS72 MAST1 WDR24 SEMA4F ZNF324B STK11 KPNB1 ANKRD39 CHCHD3 CHCHD2 SNRNP25 VBP1 GOLGA3 ZNF687 ZNF354A UBFD1 EDEM3 DPP3 CDC23 DLGAP5 ATP7B PDCD11 WDR53 NDUFA11 SPG7 SLC26A2 PSMA5 TRMU MTOR SNRPA TRIM9 FHIT DHODH KIF22 HIRA CCDC130 ROGDI DNM1 COPS7B DPH2 ZNF417 CENPQ AKAP8L LMTK2 TP53TG1 OS9 CCDC146 GINS2 MRPL4 ANP32E NUDT16 ITFG2 TCEA1 STX18-AS1 LIN37 ZSWIM3 ZSWIM1 DNAJC11 CCDC51 SND1 FAM207A CCDC159 ZNF416 AAMP NAIF1 ELAC2 CCT7 CCDC137 KDM3A CENPK BAZ2A RNF187 CPSF4 PWWP2A PSMB3 ORMDL2 PALB2 CENPM STOML2 ZCCHC17 GBF1 AP3M2 FAHD1 MRPS23 BCL2L1 UBXN6 NOL6 CDR2 ABCA7 MCM6 ARVCF KDM4B MRPL28 PRMT1 XRCC4 NOB1 MCM5 HIBADH GNG4 NMNAT1 ZRANB3 C5orf22 FAM161A ZNF563 RAB3D C1orf109 ZNF599 GINS3 LRCH4 ZSCAN32 NDUFS7 KATNB1 DOLPP1 POLR2I YIPF2 CREB3L2 RGMB CCNG1 PDIA4 IGHMBP2 SLC1A5 AP4B1 DDX55 GOSR2 TSR1 CEP152 TCERG1 MST1P2 COPZ1 DUS2 SPSB3 ARFGAP1 ZNF837 CEP85 ZNF519 NME1-NME2 GLO1 ATP6AP1 TSPAN10 CYTH2 CCNA2 RBM42 PRR11 BANF1 MANBAL HEATR5A SNRPD2 ANAPC2 TXNL4B PDAP1 CDK5RAP1 CEP164 PRPF31 NUBP2 BMS1 ARL17B TRIP4 MAP3K9 NBR1 SEC13 MCU MROH1 MLLT1 GTF3C5 SAMD4B SRP9 MRPL21 IKZF4 LLGL1 NDUFS8 TBCB ALKBH6 GNA12 ENTPD7 BCAS3 PNKP TARBP2 MAPK8IP3 ZNF91 TCF3 GNE DNAJC14 ADRM1 EARS2 RHPN1 ZMAT2 NDOR1 ALG1 HGS TIMM44 SNRPC PPIA TBL3 UBE2C LINC00205 TTC9C RHPN1-AS1 FBXO45 CDKAL1 SFXN5 DCAF11 ENO1 ZSCAN20 TMEM38A TPRN SLC39A1 PLIN3 WIPI1 ZNF367 TTLL5 CLASP1 FAM222B WIZ ATG4B CALU DDX41 MZF1 C12orf10 MSANTD4 TRAPPC6A SETD5 ANKRD11 CYB5B RPUSD3 CSTF1 CYHR1 COPE DNAL4 EIF2D RCN2 POLRMT PDXP MED16 MRPS16 ASB16-AS1 MAP3K12 MAN2C1 HRAS RAB40C TRAFD1 EIF2B1 COMTD1 CDK11B ADSL ZC3HC1 TBC1D10B PPP2R5E PNPO KHDRBS2 PSMB10 LCMT1 CYB5RL ABHD2 SDHAF1 FAM111B NFE2L1 TMEM9 TOMM40 SLC2A8 ZNF774 MCEE SLC4A1AP TRAF7 GLRX5 ZNF77 ARHGEF19 TYK2 CHD8 MPZL1 MTMR4 DCLRE1B TEFM URB2 ARMC6 MTR HOMEZ RPLP0 TMEM167A ZNF772 ZNF805 HINT2 SHKBP1 CS AP2A1 RMI1 HNRNPAB MTF2 THAP4 FAM149B1 PSMD3 PPP2R1A ZNF17 DHX38 SWSAP1 EVI5L NUP214 ELMO2 SAP30L GARNL3 KLF5 BBS12 DDX49 MAEA SCAND2P RAB4B ZNF691 CTPS1 IPO4 DRAP1 LAMTOR4 RMI2 SNHG10 DCTN3 TANGO2 TMEM203 IK HNRNPA1 SKA2 ABCB8 WDR12	up	***
MIR9985	0.0000699	0.0023705	0.5384341	-0.2346467	-1.408359	529	PRMT8 SLC24A4 RAB11FIP1 SEMA6A STAC MS4A7 ENDOU PPARG GATA2 SNX10 RAPGEF2 ST6GALNAC3 SIK1 CDH5 ARRDC4 ZBTB34 TMEM170B ST3GAL6 KIAA1109 LONRF1 QKI HMGCR DYRK1A KCNN3 NR3C1 TGFBR3 RGPD5 HEG1 ERG SEMA6D ATP2B1 HBEGF BEST1 LIFR ASAH1 ITGA5 BTG2 FZD4 LITAF CAMTA1 SLC7A11 ABHD6 GATA3 SFRP1 SPRY2 ITSN2 SOX7 SLC7A2 TAPT1 NRARP FOXO1 BNIP2 ZCCHC24 CDIP1 SSH1 MGAT4A PDE3B NPAS3 NR1D2 ARHGEF26 SHC4 SHE PTGER3 RNF139 PEAK1 KPNA3 RUFY3 NRBF2 FAM76B AKIRIN1 SNN ZNF426 BTG1 USP25 PDK4 TMEM9B CREBRF DCP1A SLC25A25 ID4 PDHX CCNY RYBP DNAJC27 PSEN1 RNF141 SLC9B1 NXF1 NECAP1 C2CD2 PSMA1 C20orf194 HIC1 C11orf58 BMP3 DDX5 GRB2 CREB1 KBTBD8 RC3H1 HSD17B12 TSPYL1 GFPT2 CELF2 AGFG1 POGLUT1 NIPAL4 NECAB1 FOXO3 SLC35F1 FOSB PKIA AKIRIN2 VAV3 PDS5B RSBN1L SBF2 SLC24A1 NPTN GATA6 KAT2B TMA7 PHLPP2 ATAD2B INO80D AMD1 GEM GLTP ABL2 CDC42EP3 TRAPPC8 PTCH1 VSIG10 MAP3K4 LYSMD3 MARC1 RNF38 SCAI EPB41L4A CECR2 TLK2 PRKG1 MMD PAIP2 NRP2 C1orf52 NABP1 LPAR6 GSPT1 SMAD4 MIER3 CACNA2D3 HSDL1 SPATA13 FCRL1 SLC16A10 UBE2V1 ACVR1C PLAG1	down	**
HSF1_01	0.0049660	0.0498070	0.4070179	-0.2602238	-1.404857	209	SLC24A4 KRT81 GPR17 GREB1 IZUMO1 BMPR2 NFATC3 TRIB1 CACNA2D2 PLXNA2 EIF5 HSPB1 LUZP1 GATA3 JAM3 LAMTOR3 KANK2 ADAMTS9 SOCS2 SOCS5 CADM1 UBE2E2 DUSP1 PPP2R5C ILDR2 PTGIS TSACC RSRC2 GPBP1 ID4 CNTF CREM PIKFYVE NECAP1 JUN DNAJA1 MBNL2 ATL2 FSTL3 GRIK1 FOS HIVEP2 TREX1 TSHZ3 FLNC CHORDC1 EHD1 HNRNPA2B1 JMJD6 GLRA3 TGIF1 ATP6V1A PIM1 TMEM107 MYOCD STX12 ACTN2 VASH1 RTN1 TAB2 HSPA8 EPHA2 SREBF2 TLK1 GIMAP4 SHISA6 DNAJB5	down	*
MIR4803	0.0003267	0.0076194	0.4984931	-0.2409214	-1.404067	376	EREG COL25A1 EDNRB SGK3 DENND5A GATA2 ZC3H12C TMEM170B BDNF VAT1L CALCRL QKI FBXO3 NR3C1 GIMAP6 TGFBR2 RCHY1 BRINP3 ATP2B1 HBEGF HECW2 RAPGEF4 LIFR ASAH1 ZNF503 GLS CAV2 SLC7A11 DACH1 FOXJ3 ZEB1 GPM6A PPP3CC ATP10A EVI2B NRARP MTMR6 ACSL3 ITM2B SLC38A11 REST LEPROTL1 KLF11 TNFSF15 ADAMTS9 FBXL3 ABCC4 TADA2B RECK SMAD7 N4BP1 VEPH1 VPS37A DDHD1 PHACTR2 APPL1 SERPINB8 JUN GABPA SNX29 EPC1 MTMR9 APBB2 TTC14 CREB1 LPCAT2 SLC10A7 PDZD2 YWHAZ AGFG1 CTTNBP2 CDK17 KLRC2 ZFAND6 CC2D2B GNAI1 ATP6V1A PPIG LTBP1 PDE4B ARPP19 INO80D HACE1 JUND BMP2K CEP170 TIAM1 LRP12 BRWD1 ZDHHC21 CREBBP LIMCH1 STK4 TMX2 CAMSAP2 FGFR1 DOCK4 ZFPM2 CNOT8 EIF4A2 SMAD4 HNRNPH1 ACVR1C EGR1 ACSM5 CDKN1B FUS PRKCH SH3GLB1 KIAA2026 CD109 CSNK1G3 CCNT2 PRTG UBE2W CHAC2 PIAS2 MTSS1 ANGPT2 SCAF11 MAN1A1 OMA1 ROBO2 TMEM165 SEMA5A CMSS1 MAPK7 PJA2 ZNF667 KLRC1 VPS13C FPGT-TNNI3K FBXO33 SON CSTF2T CAAP1 DYRK4 LEPROT TANK EIF3J	down	**
HLF_01	0.0028124	0.0338491	0.4317077	-0.2621674	-1.403918	197	SECISBP2L CALCRL AQP9 CTDSP1 CDC42 FBXO3 SEMA6D EIF4A1 SH2B3 FOXA2 ZDHHC2 ZBTB21 FOXP1 ADRB2 WNT3A PDE4D AGO3 HNRNPA3 KLF9 USP2 TNFSF15 RMDN3 CLIC4 DPH3 CADM1 UBE2E2 GPR85 ELMSAN1 CRIM1 NCKAP5 CNTF OXNAD1 RHOBTB2 PIK3R1 DDX5 MBNL2 PREX2 DENND4A CELF2 SPRY4 CALM1 TNFSF13 FOXO3 TREX1 TFEB ZFYVE9 TSC22D1 ATXN1 COL15A1 TOB1 SYT11 EPN2 SPIB SREBF2 PKNOX2 CTSC ZDHHC5 PRKG1 RORA CACNA2D3 DNAJA2 HNRNPH1 FNBP1 MAP4 HERPUD1 PLAG1 AKTIP ING1	down	*
MIR543	0.0009149	0.0154449	0.4772708	-0.2504227	-1.403514	278	EREG AKAP5 IL1A MRPS18C ST6GALNAC3 ZBTB34 OTUD1 RASAL2 QKI AKAP7 GPCPD1 SRSF7 C5AR1 NR3C1 TEX2 HEG1 LIFR EIF1 FZD4 KLF6 SLC7A11 DACH1 TCF7L2 ATP10A MSR1 PER3 TBC1D9 KCNMA1 YBX3 GAPVD1 NR1D2 AQP4 ARHGEF26 CD302 ZBTB43 PEAK1 CYP26B1 IKZF5 PIAS1 C2orf69 GPBP1 CREBRF FMNL2 DCP1A ID4 METAP1 COPS2 HECA RASSF10 PDE5A DHX15 EEA1 THUMPD1 FRYL CREB1 SLC10A7 ZNF597 PREX2 CGGBP1 BCL6B PKD2 MARC2 IRF5 GOLGA8R BAZ2B ABHD13 GOLGA8H PPP3R1 BMP2K CTTNBP2NL CYB5R4 TBC1D1 CTSC PRKG1 C21orf91 RORA CNTNAP3B FAM13B EIF4A2 RNF13 RABGEF1 DMXL2 YTHDC1 PSIP1 ACVR1C PLAG1 CHML CCDC112 MAPK1 CLOCK ING1 C16orf95 SH3GLB1 PLXDC2 ATP1B1 PRTG TRPM7 UBE2W SPTY2D1 GOLGA8B	down	*
GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D	0.0000487	0.0017628	0.5573322	-0.2358591	-1.402801	510	SMAD6 WEE1 SLC24A4 RAB11FIP1 EPAS1 EREG SASH1 TAL1 FGD5 TBX3 DPYSL2 ST6GALNAC3 SIK1 EGR2 NEDD4L QKI CRY2 BMPR2 PAFAH1B2 S1PR1 DYRK1A OTUD4 TGFBR2 TXNIP ZBTB4 RAPGEF4 MAP3K8 PBX3 LUZP1 CAMTA1 PEX5L PPP2R2A FOXJ3 PPP3CA RB1 SRSF2 LHX6 NDEL1 CRK AKT3 BTG3 MCL1 FBXL5 EFCAB14 TBC1D9 TLE4 KCNMA1 PTPRO BNIP2 PPP6R3 KIAA0513 TNFSF12 KLF9 KLF11 ATL3 CDKN1A NPAS3 NKIRAS1 CEP57 CCND2 M6PR FRMD4A CCSER2 ELK3 SMAD7 CLIP4 CYP26B1 PAFAH1B1 KPNA3 CRIM1 TANC1 RSRC2 TOPORS SERTAD2 CREBRF FLT1 DNAJC27 PKNOX1 PHTF2 DDHD1 PLEKHA3 PPP6C ANKRD9 HECA C2CD2 SH3BP5 ZFP91 ARHGEF10 RABGAP1 APBB2 VPS26A DUSP8 PIK3R1 DDX5 KBTBD8 MAPK4 RPS6KA1 NAA30 RASSF2 DEDD IP6K1 MORF4L1 SPRY4 YPEL2 YTHDF3 PKD2 TSHZ3 PKIA BTBD7 TIMP2 ZFYVE9 CDC37L1 C16orf72 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 PLEKHO2 KAT2B PHLPP2 RBL2 INTS6 INO80 OSR1 EPHA4 SSH2 NPAT FOXJ2 PTEN SKI DNAJB9 FAM126B FAM13C ITCH DAZAP2 LDLR NRP2 ZFPM2 NABP1 WDFY3 SPOPL PURB EHD3 ANO6 TRIM36 EIF4G2 ZFYVE26 ARHGEF18 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 NR4A2 CLOCK DCUN1D3 TGOLN2 CMPK1 RB1CC1	down	**
MIR524_5P	0.0000016	0.0001535	0.6435518	-0.2236029	-1.396971	812	AJAP1 MGAT3 SC5D IL1A SGK3 TAL1 SECISBP2L CPEB2 LTA4H SLC16A4 PTPRE LIPA PTPRB ZBTB34 TMEM170B BDNF PLEKHF2 MED4 DDX6 QKI DYRK1A CDC42 FBXO3 GNPTAB TSHZ1 TET2 NFATC3 SPCS3 HEG1 TMX4 ZEB2 TXNIP ARHGAP29 WWC2 ATP2B1 LACTB CACNA2D2 LATS2 RAB33B BZW1 MAP3K8 RANBP9 COX18 KLF6 RNF182 GLS CAV2 PTX3 CAMTA1 ADIPOR1 EIF4E DACH1 FOXJ3 PPP3CA RGCC SRSF2 LHX6 HNRNPDL TFEC HNRNPU TCF7L2 UBE2D3 TFRC RAB14 ZYG11B GPM6A ZMIZ1 PTPN12 MSR1 TLE4 RAB12 FOXO1 DGKE SCP2 BNIP2 TCP11L2 ACSL3 KLF4 FAM76A REST PRKD3 DRAM1 TJP1 SEC24B C1QTNF7 PER2 LRRC40 IRAK2 CYP20A1 PNRC1 CEP57 ZBTB43 CLK4 UBE2B MBD2 RAP1GDS1 SLC6A6 PRICKLE2 OXSR1 UBASH3B PAFAH1B1 BCLAF1 SMNDC1 FAM76B AKIRIN1 EFR3A CNOT6L RSRC2 CNRIP1 NCOA1 SIAH1 FAM102B USP25 RBM39 GPBP1 CREBRF PRKRA SCEL ID4 ELF1 PDIK1L CREM YBX1 DDHD1 SGK1 HSD17B13 EBF2 HCFC2 PPP6C SERPINB8 JUN ARL5B MITF STAT4 C20orf194 GABPA GLUD1 DDX17 C11orf58 BMP3 MSRB3 HSPA1B OSTM1 EPC1 SKIL ENPP4 SP3 ACKR3 CREB1 ZNRF3 PREX2 CGGBP1 MEAF6 AGFG1 CTTNBP2 PELI1 AZI2 HIVEP2 USP7 PPTC7 MAPK8 PKIA RIN2 TTBK2 BTBD7 EPHA3 SORT1 GOLGA8R VAV3 TCF4 ATG2B SERPINB1 VAMP4 RSBN1L SBF2 GOLGA8H ZC3H12D ATXN1 CSDE1 PPP3R1 GNB4 GNA13 KAT2B ADAM10 PDE4B CALB1 ETS2 MBNL1 ATAD2B ARPP19 SMAD2 INO80D RNF138 SESN1 INTS6 SLC34A2 ZNF583 CEBPD LRP12 TRAPPC8 TAB2 FBXO30 ARIH1 MEGF9 HNRNPK G3BP2 GRIN3A SRSF10 KPNA4 VSIG10 NPAT TTC28 DOCK10 SCAI FAM126B KIF1B RORA FAM13C DOCK4 RHOT1 SFPQ GSPT1 CNOT8 WDFY3 PUM1 EID1 SLC44A5 MIS18BP1 SPATA13 INTS10 ZBTB44 IRF2 HNRNPH1 VPS13D PSIP1 EGR1 TMEM50A DUSP6 TMEM30A ZNF106 CENPC NR4A2 HIPK1 ATF2 UBA6 MAPK1 SSB CLOCK	down	***
MIR302A_3P_MIR302B_3P_MIR302C_3P_MIR302D_3P	0.0009112	0.0154449	0.4772708	-0.2459598	-1.395898	303	RAB11FIP1 TMEM100 EDNRB FGD5 SOWAHC RDX TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 ZCCHC24 REST PDE8A NPAS3 ST7L CYP20A1 SHC4 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 SLC16A10 PLAG1 ARHGEF17 CFL2	down	*
AML1_01	0.0016454	0.0230023	0.4550599	-0.2508879	-1.386103	238	GPD1 DAB1 SLC12A6 CD101 EGR2 LMO2 RASAL2 CORO1C SLC15A3 CBL IL23A CYP17A1 UBL3 ENTPD1 SWT1 PICALM LUZP1 HLX GPBP1L1 ZBTB8A NR4A1 ARHGEF2 DIABLO FLI1 MOAP1 ID3 GRK5 MPL CADM1 PDE3B VIM FRMD4A XCL2 FCER1G TBX5 ADAMTS8 MIR17HG CRTAC1 FOXN3 SCEL CREM BCAR3 RGS18 PSMA1 CELF1 MSRB3 ATP6V0B RHOG GRASP SNX1 CAP1	down	*
AML1_Q6	0.0016454	0.0230023	0.4550599	-0.2508879	-1.386103	238	GPD1 DAB1 SLC12A6 CD101 EGR2 LMO2 RASAL2 CORO1C SLC15A3 CBL IL23A CYP17A1 UBL3 ENTPD1 SWT1 PICALM LUZP1 HLX GPBP1L1 ZBTB8A NR4A1 ARHGEF2 DIABLO FLI1 MOAP1 ID3 GRK5 MPL CADM1 PDE3B VIM FRMD4A XCL2 FCER1G TBX5 ADAMTS8 MIR17HG CRTAC1 FOXN3 SCEL CREM BCAR3 RGS18 PSMA1 CELF1 MSRB3 ATP6V0B RHOG GRASP SNX1 CAP1	down	*
SUPT20H_TARGET_GENES	0.0000366	0.0014264	0.5573322	0.2703183	1.384757	1123	RUVBL1 TICRR LYSMD1 PDCD6 BUB1B NUP107 ZNF84 ZNF12 C17orf75 PAGR1 NDC80 PHF14 TSFM MKS1 BRCA1 NOL12 PMS2CL POLE SAYSD1 FLAD1 TTC26 NUF2 YEATS4 IFT27 CDCA8 CENPA ACAD9 GPI WDR70 ACOT8 NBR2 FBXL19-AS1 CKLF-CMTM1 XRCC2 COPB2 MIS18A LIPE-AS1 DZANK1 LRRC27 UQCC1 LSM5 SPPL2B FAM220A NME1 TOP3B RANBP1 CEP250 CLPTM1L TMEM41A SMARCD3 RAB11B-AS1 DYRK1B BBS1 BOD1 KIF15 FBXW9 CCDC77 CENPL RFXANK IQCD NUP155 PSENEN POLA2 GTPBP3 CENPW COASY TPCN1 SPEF2 RBM28 NSUN2 RNU6-418P ERAL1 MRPL3 CMBL FANCD2 BLOC1S1 CCDC58 EMG1 TARS2 SLC2A11 FAM162A OAZ3 ZNHIT1 C7orf50 TRMT61B RAD51AP1 DCTPP1 ABCB9 ANKRD16 TRMT2A SPC24 B4GALT7 EEFSEC SPAG8 OGFOD2 RAD18 FBXL19 CNOT3 MNAT1 SRRM5 COQ9 CNPY2 SKP2 RECQL5 DDX56 CKLF RBAK ISOC2 CDKN2C HPS4 FRMD5 DDX51 ANAPC5 PABPN1 HDGF CDK12 SSBP1 PHF12 NPM3 STX18 VANGL2 WDR31 PRPF6 AP5Z1 PMEL BPGM DHX33 ENPP3 ANKRD26 FSBP TSPAN31 USP42 MTBP HMGXB3 PSMC4 RECQL4 CENPP WDR24 UNC45A CHCHD3 EFTUD2 GOLGA3 ZNF687 MZT2B ILF2 CCDC142 CDC23 VIPAS39 DCAKD WDR53 SPG7 FOXRED1 GALK2 TSNAXIP1 MTOR DNAJA3 AARSD1 RAD9A LONP1 PIGG HIRA TIGD6 CCDC130 FBXO15 COPS7B ADAR CENPQ RHBDD3 AKAP8L JMJD4 MRPL4 PDRG1 MTND5P11 STX18-AS1 ZSWIM3 DNAJC11 PRMT7 GFM2 GK5 FAM207A C12orf73 MAGOHB CEP128 PRRG2 CCDC159 ZBTB45 NAIF1 NIF3L1 CENPK KLC4 FAM71E1 EFCAB7 LSG1 PWWP2A VPS25 TMEM106B PALB2 STOML2 AAAS GBF1 FAF1 FBXO22 FAHD1 MRPS23 HMGB3P22 UBXN6 PPP6R1 MRPL24 MYPOP MRPL28 WDR83 RPL7L1 MED24 PRMT1 NOSIP NOC4L NMNAT1 LSM7 DDX23 SNAP47 MRPL53 RTEL1-TNFRSF6B SRSF1 HAX1 RAB3D C1orf109 LRCH4 STMN3 NDUFS7 KATNB1 DNAJC21 EXOSC5 YIPF2 POLR3E IGHMBP2 MED27 DDX55 TCERG1 MST1P2 COPZ1 DUS2 SPSB3 GTPBP10 PRMT5 LRRC14 ZNF580 AP2S1 NME1-NME2 AMN1 PRPF18 MCRS1 CYTH2 RPS26 RRNAD1 CCNA2 RBM42 RN7SL1 BANF1 ABCF3 RTEL1 DENR SCNM1 RNF121 MRPL55 ANAPC2 TMEM141 TXNL4B GTPBP2 CDK5RAP1 ABCF2 TTC31 WDR4 PRPF31 ACSF3 NUBP2 BMS1 N6AMT1 TTC1 TRIP4 NBR1 SEC13 PFKM GTF3C5 MRPL9 MRPL21 RPUSD2 RPRD2 VPS9D1 ACP1 AGBL5 TMEM101 NUBPL AURKAIP1 RBM19 ZNF131 CIAPIN1 TCF3 POP4 SMPD4 ZMAT2 NDOR1 ALG1 LRSAM1 NMT1 TRUB1 SNRPC TBL3 PIGL FBXO45 FAM185A CDKAL1 MRPL20 PWP1 DCAF11 TMEM38A RAD1 MRPL48 NAT10 TK2 TTLL5 TRUB2 FAM222B MOK DDX41 BRIX1 TRAPPC6A ANKRD11 SLC33A1 COPE KIAA0586 INO80B CEP290 EIF2D HEXIM2 RPL23A MRTO4 BMF DHDDS TMEM63C PPP1R13L MAN2C1 SPHK2 METTL4 C12orf43 RAB40C RANBP10 TMEM259 RPL36 ZC3HC1 TBC1D10B ZNF276 ROPN1L ABHD2 TNPO3 NFE2L1 OPA1 AP2B1 SAFB TMEM9 NSL1 ZKSCAN4 MRPL2 TOMM40 MCEE MAD2L1BP SLC4A1AP CTU2 SRFBP1 GLRX5 ZNF77 TEFM PRCC RPS6KB2 SAFB2 ARMC6 CXXC1 SLC27A5 CACTIN EHMT1 AP2A1 CCDC86 XRCC5 PLOD3 TXN2 CMTM3 VWA5A LRPPRC FAM149B1 SLC7A6OS C1orf74 TIMM9 DYNLT1 E2F4 PPP2R1A NUDCD1 STRIP1 ZNF17 INTS9 DHX38 KMT2D C5orf49 EVI5L NUP214 DDX49 SUGP2 PTPN23 COQ4 SMC4 IPO4 GTPBP4 METTL9 BECN1 TMEM183A EEF1D SNHG10 SKA3 TMEM203 IK HNRNPA1 ABCB8 CDC5L KLHL20 GTF3A KHSRP BUB3 DNAJC2 SLC39A3 USP19 DCTN5 CIC MRPL13 DARS2 CLPB NVL HNRNPUL1 AHCYL2 ZC3H3 PET100 JRK IFT74 BCKDHA DAGLB ENSA REXO4 COX16 VTI1A KANSL1 DDX19A EMC10 ZBTB17 ITGB3BP BLOC1S3 WDR92 MAPKAPK5 CRTC2 CPSF1 MLST8 TSKU P4HA3 MT-RNR1 IMMP1L DRG2	up	**
MIR607	0.0000026	0.0002225	0.6272567	-0.2216829	-1.384527	815	TRIM71 GPATCH11 FOXF1 ZMYND15 SWAP70 ABHD5 SPN ATXN3 LHCGR PTPRB KL TMEM170B PLEKHF2 BACH1 KIAA1109 CORO1C THAP2 AQP9 QKI BMPR2 ZCCHC2 GTF2I PLEKHA1 PAFAH1B2 MTMR10 IDI1 EOGT MOB1B RCHY1 SCARA3 SPCS3 ZEB2 ZBTB4 CNST STARD4 ATP2B1 DNAJC3 LACTB TACC1 FAM124A LATS2 BZW1 SERINC1 RNF144B NLK SPIRE1 KLF10 KLF6 SLC7A11 PPP2R2A ZBTB8A FOXJ3 SRSF2 CD93 SPRY2 ZFYVE16 TFEC CYP4V2 GPM6A TIPARP PTPN12 CWC22 TBC1D9 RAB12 FOXO1 KCNMA1 PPP6R3 CASP1 TSPAN12 ITM2B STK17B KLF7 SPAG9 ERP44 MGAT4A NR1D2 NKIRAS1 CTBS TADA2B C9orf72 UXS1 CD302 RECK LBH ACTR3 UBE2B ILDR2 PEAK1 GNAQ ZNF706 KIAA0408 UBASH3B PRDM5 TP53BP2 NRBF2 IKZF5 TLL1 EFR3A MEDAG LIN7A ACTR2 SERTAD2 ARL6IP5 TFAP2E FLT1 CCNY RNF149 PDIK1L CREM SYNPO2 PKNOX1 PHTF2 CTSS NEK7 APPL1 RAB8B PDCD6IP NECAP1 ARL5B MITF LRCH1 GABPA ZFP91 KCTD12 BMP3 MSRB3 CNTN4 OSTM1 FOXN2 MTMR9 VPS26A TBC1D12 DHX15 FYTTD1 TTC14 SP3 ACKR3 CD83 DDX5 CREB1 PTGER2 COBLL1 FSD2 RC3H1 FSD1L PRKACA PDZD2 PREX2 NAA30 DENND4A ZNF407 BLOC1S6 AGFG1 POGLUT1 SLC25A24 PELI1 AGPS CDK17 AZI2 HIVEP2 YTHDF3 PKD2 TSHZ3 NAA16 SYPL2 AZIN1 AKIRIN2 STRN AP1G1 NDUFA5 ZBTB1 SRSF4 PDS5B HECW1 CRYZL1 ABHD13 TEX30 VAMP4 FEM1B MTMR2 MIA3 MAP3K2 PLSCR4 PPP3R1 TAGAP THAP9 TMEM70 STX12 MBNL1 SMAD2 INO80D BMP2K GEM INTS6 NEK1 PDLIM5 SFT2D1 ACAP2 TEX10 THAP6 FBXO30 ARIH1 CYP2U1 RBM18 UBE2D1 TBC1D1 USH2A POLR2M ZNF471 ZDHHC21 RBMS3 LYSMD3 CUL3 BCAT1 SCAI DNAJB9 TLK2 PRKG1 PDE8B C21orf91 RORA FAM13C FAM13B GSPT1 NDUFAF5 CNOT8 SPOPL PURB MACROD2 BANK1 ARFGAP3 SPATA13 ZBTB44 SLFN11	down	***
MIR548AZ_3P	0.0002216	0.0058645	0.5188481	-0.2367382	-1.384102	419	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 KLHL8 MED4 QKI BMPR2 ARL8B PRKAR1A MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP MYO1B GPR85 CXXC4 PLEKHB2 N4BP2L1 UTP23 GNAQ TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 MED28 EBF2 NEK7 PIKFYVE HCFC2 RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 BMI1 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	**
H1_6_TARGET_GENES	0.0034159	0.0380435	0.4317077	0.2832683	1.382919	390	CEACAM1 MROH3P FOXM1 SLC2A1-AS1 HOXB-AS3 IGSF9 GPT WFDC3 GMDS SLC13A3 TFAP2A SLFN13 NEK2 IQCE SLC2A1 TTC39A LRRC37A3 DNMT3B ZNF283 KIAA0895 EPS8L1 C1orf220 NOS1AP SMARCD3 C19orf48 OSBPL2 SYTL2 RHNO1 EEF1E1 AURKA C1orf226 LPIN3 LIPE WDHD1 ZNF146 ANKRD13B SNHG11 B3GNTL1 LIG1 SRD5A3-AS1 EHHADH AKT2 LRRC61 B4GALT7 GEMIN7 DDR1 PPP5C SRRM5 TULP3 AFAP1L2 APLP1 SUPT5H CROCC DNTTIP1 PACS1 STX18 MAP3K10 ACTR3C LARP1 CPNE1 CCDC88C COA4 PPP1R36 C9orf43 ACBD6 CATSPERG OVOL3 AKR1E2 COL1A1 TUBG1 SEC16B C19orf47 SPG7 ALDH7A1 COPS7B ZNF234 PPOX RHBDD3 ANP32E STX18-AS1 LAMTOR2 CDK13 PRRG2 ZBTB45 ZBTB7B PROX1 FAM71E1 KCNB1 CA11 BLCAP CYP2S1 NOSIP TMEM147 GNG4 ZNF783 C1orf56 RTEL1-TNFRSF6B STMN3 IGHMBP2 SLC1A5 ABCD4 WDR27 ZNF780A CNTN2 NUP62 AP2S1 CYTH2 RBM42 ECH1 RTEL1 INO80E MARK4 ZSCAN22 MRPL21 SNRNP70 ZNF573 AURKAIP1 GNA12 RNF213	up	*
ZNF654_TARGET_GENES	0.0000035	0.0002735	0.6272567	0.2681426	1.380509	1377	CPNE4 IGLV4-69 DKK1 UNC5CL PRLR STYK1 GPR156 DDX11 ENTPD2 MEGF10 SPICE1 SPATA24 EPHB3 EGLN3 MDM1 IGSF9 SPOCK1 DNAH2 MCM10 C1QTNF6 PMFBP1 TFAP2A S100A2 BUB1B TMEM51-AS1 SYNPR IGLV1-36 COIL ADRA2A DOC2A POLQ TM4SF18 FAM177B NPAS1 SEMA4B SCN3A MND1 COL27A1 SLC2A1 TSFM PRIM2 TTC39A PLEKHH1 SDK2 C6orf141 EFNA3 CDK4 ASIC1 XKR9 ALDH1L1 CABIN1 L3MBTL1 PCDHGA1 CEP70 CHRNA7 BAIAP2L1 EFNA4 AURKB ECT2 ESPL1 CUEDC1 RGS6 GRIN2A CDC6 TFDP2 VSTM2L ZNF221 C4orf19 AGR2 SPATS2 SPINT2 LSR XPNPEP1 ANKRD36B CLCN2 KHDC1 ZNF3 LIPE-AS1 ARHGAP40 GINS4 VILL B4GALT4 EPHB1 DZANK1 CDK5RAP3 AP1G2 SLC4A8 UQCC1 TRIM45 LSM5 NUB1 TAMM41 FAM220A SYT12 NME1 OSBP2 TNNT2 LTB4R2 SMARCD3 NLE1 FOXA1 BCYRN1 RND2 DCBLD2 RNF216P1 FSIP2 AUNIP TOP2A GPER1 BPHL SPTB NDUFS2 METTL7B TPR IL12B DPCD C1RL LPIN3 SPEF2 RBM28 RNF43 SGPL1 FNDC5 DUSP23 CCDC114 FHOD3 WDR73 WDR66 XXYLT1 LETMD1 SARS2 ARMC12 HEBP2 ABCB6 ZNF786 RAB13 DCTPP1 THAP10 DNAAF3 OXTR MRPS11 IPO9 TRGV1 FBXL19 INPP4B PHB FAM157A SLC18B1 SYMPK HOXB5 TSHR FBXO16 RGS4 ALDOA IGLV1-40 NRG4 ALG3 MGLL MGAT4B UQCR11 KCNJ2 GPX8 IKBKB RNF216 NUSAP1 MB ASF1B C2orf50 DNER SLC39A11 DMKN CDK12 LINGO1 CLMN EXOSC2 TNFRSF21 BCAS4 SSUH2 ARPC1A ZSCAN25 TNK2 GDPD1 OAT SYN3 CCNJL LRRC9 MRPL17 FAM98C RUFY4 GNPNAT1 SDCBP2 ENPP3 KLHDC9 NEK5 CCDC88C NUP205 POC1B MRPS12 PLCG1 ARTN TMEM120B RNF150 SNRPE TMEM51 ABCA4 NOP2 PCDHGA2 KLHL22 MAST1 CPT1B ANXA2R UNC45A TPD52L2 EFTUD2 TBX1 GIPC1 MZT2A ZNF354A CATSPERG GRAMD1A SPEF1 CAPS2 INTS7 ZGPAT ARFRP1 CCDC142 RHOC COL1A1 CDK3 IGLV6-57 NADK2 SEC16B VPS41 DNAH7 ADNP TACC3 MLF2 DHRS4-AS1 COL9A2 RAD9A C19orf12 SLC37A4 MRPL11 RAD51D UBE3D RGS22 SUDS3 ARF5 ACBD4 UBE2Q1 TMTC2 POMT2 HM13-IT1 CSNK1G1 MEGF8 SOX2-OT LMTK2 SRGAP1 ATG9B PDRG1 GRIN3B TJAP1 SPAG1 XPR1 DAP3 LRWD1 IGLV1-47 SYNGAP1 TSEN54 ZNF282 EPB41L4B FLG-AS1 TYRO3 PEX10 ZBTB45 ENC1 TMEM232 ELAC2 DNAJB13 YARS2 ARHGAP12 NR6A1 BAZ2A P4HA1 KLC4 TMEM234 STRN4 LINC00910 KCNB1 COG1 DGKA ANKRD6 AHCYL1 OLFML3 RIN1 AAAS CA11 FTCD ASB6 SIRT4 MAN2A1 ZNF616 NRXN2 RRP9 AP3M2 SLC6A1 POP7 BCL2L1 FITM2 NOL6 PELO CDK5RAP2 KRT8 PEX5 TTC34 DYNC1LI2 WDR83 MED24 PRMT1 DHX8 RNF215 KPTN NMNAT1 DDX23 ADD3 HAX1 EDAR POLR3E SUOX RCC1 RSPH4A SMARCC2 ANK3 GAD1 SF3A2 ADAMTS17 ZNF274 TCERG1 COPZ1 PRMT5 CNTN2 IL12A CEP85 NME1-NME2 B9D1 ZNF212 ENGASE TMEM117 RPL5P11 DENR POLR3B SCNM1 PCBD2 ICK CLUAP1 HOOK2 CCDC88B TTC1 TOMM40L ATG4D PPP6R2 LRRC71 GRAMD1B OXCT1 MLLT1 TYSND1 SNX19 POMK ZNF610 DIP2B SNUPN RBM19 BCAS3 GOSR1 RASGRF1 RPP25L ADRM1 ADAM15 POP4 TRIB2 CGN NPTX1 ALG1 TP53 PDZD7 ZNF341 ALOX15 TIMM44 FBXO34 IDUA MRPS27 SLC36A1 NNMT LINC00205 TAF4 LRRC4C TMEM98 ZMYND10 RAD1 SPATA20 RRS1 NLGN1 KHNYN SH3GL1 CLASP1 ATG4B MOK COL16A1 ACAD8 ANKRD11 PCTP ALKBH2 CLNS1A TPM1 F5 GLIPR1L1 DAZAP1 UNC119 KCNH4 NDUFAF6 EIF2D STK33 VPS18 ZNF511 EID2 DNAAF1 SEC31B ST8SIA1 SCRN2 ARSG SHQ1 MAN2C1 VPS16 ITGB5 CRYGS PDK2 SH3RF2 UBAP1L NAT1 PRPF19 PARL DSN1 COMTD1 ADSL RPL36 HDAC10 RBL1	up	***
MIR3910	0.0003711	0.0084038	0.4984931	-0.2389202	-1.379904	352	RTKN2 SLC31A2 SEMA6A STAC LRRC8C MBOAT2 RCOR1 OTUD1 RGS9 QKI OTUD4 EDEM1 TRA2B TTL ZNF503 ANXA5 LCP1 PPP2R2A PPP3CA PTPN12 CWC22 EFCAB14 AGO4 ROCK2 AMOTL1 KLF4 SLC7A8 VASP TJP1 KLF7 SNIP1 RBMS1 UBE2B PIK3C2A ADIPOR2 MBD2 CUL5 SLC6A6 ZNF706 RBM44 FKBP15 AKIRIN1 TLL1 TAF13 RAB6A MYLIP MYO1C VAMP3 GZF1 CNTN3 CCDC50 RHOG APBB2 FERMT2 ENPP4 SP3 DDX5 PCGF5 SLC10A7 PDZD2 FAM177A1 ITGA11 ACSL1 CD164 PPTC7 EPHA3 PEA15 C16orf72 MAP3K2 CCDC68 ANKRD12 NPTN GNA13 RXRA PDLIM5 SLC31A1 SCN7A EPN2 DCTN4 CYP2U1 SSH2 ULK2 LYSMD3 KATNA1 RASSF8 FAM126B PRKG1 MMD ANXA11 NR3C2 MIER3 USP48 TRIM36 ARRDC2 KLC1 REEP1 SUGT1 CDON CFL2	down	**
MIR181A_5P_MIR181B_5P	0.0002666	0.0067664	0.4984931	-0.2301248	-1.379438	503	TRIM71 IL1A ATXN3 ADCY9 MBOAT2 RAB3C SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 OTUD4 ZBTB2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 ADARB1 AGO4 PER3 ADO SLC38A11 NR1D2 TADA2B RECK ZBTB43 UBE2B ELMSAN1 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF CDC40 PHTF2 NEK7 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 IRS2 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL PKNOX2 LIMCH1 RASSF8 FNIP2 CECR2 FAM126B KIF1B RORA DOCK4 GRB10 MIER3 DMXL2 CBX7 KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1	down	**
MIR181C_5P	0.0001288	0.0039064	0.5188481	-0.2300582	-1.378613	504	TRIM71 IL1A ATXN3 ADCY9 MBOAT2 RAB3C SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 OTUD4 ZBTB2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 ADARB1 AGO4 PER3 ADO SLC38A11 NR1D2 TADA2B RECK ZBTB43 UBE2B ELMSAN1 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF CDC40 PHTF2 NEK7 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 IRS2 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL PKNOX2 LIMCH1 RASSF8 FNIP2 CECR2 FAM126B KIF1B RORA DOCK4 GRB10 MIER3 DMXL2 CBX7 KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1	down	**
MIR181D_5P	0.0001960	0.0052603	0.5188481	-0.2306639	-1.377273	502	TRIM71 IL1A ATXN3 ADCY9 MBOAT2 RAB3C SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 OTUD4 ZBTB2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 ADARB1 AGO4 PER3 ADO SLC38A11 NR1D2 TADA2B RECK ZBTB43 UBE2B ELMSAN1 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF CDC40 PHTF2 NEK7 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 IRS2 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL PKNOX2 LIMCH1 RASSF8 FNIP2 CECR2 FAM126B KIF1B RORA DOCK4 GRB10 MIER3 DMXL2 CBX7 KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1	down	**
MIR656_3P	0.0005111	0.0104766	0.4772708	-0.2405526	-1.376679	342	EREG EDNRB USP12 ZC3H12C PTP4A2 PTPRE ST6GALNAC3 KL BDNF FYN CD44 CCDC88A BACH1 RASAL2 CALCRL VAMP2 KCNN3 MOB1B PTPRM SBDS RAP1A CAV2 NR4A1 RGCC TNS1 TMEM41B ZEB1 FBXO8 MSR1 RAB12 SGTB KLF4 ZFAND5 CEBPA MYO1B GAPVD1 NPR3 GMPR SSH1 CCND2 UBE2B DUSP1 BRF2 TBX5 PPP2R5A CYP26B1 NCKAP5 CDKN2AIP TDRD7 FOXN3 SACM1L SPIN1 CREBRF FRY ELF1 KIF13A NEK7 INPP5B NXF1 TMTC1 CPEB4 BMP3 CNTN4 JUNB SKIL EEA1 SP3 FRYL IDS CREB1 COBLL1 CXCL5 UVRAG OCIAD1 KLF2 YPEL2 ZNF175 FAM204A DDHD2 STRN NDUFA5 SERPINB1 TEC SBF2 GOLGA8H KYNU RIMKLB KAT2B SMAD2 ABL2 SFT2D1 LMOD1 SEC63 USPL1 SIK3 PTCH1 ZDHHC21 TMEM184B SSH2 TIMP3 DOCK10 PRKG1 MMD C21orf91 RORA FAM13B NAA15 EIF4A2	down	*
FXR1_TARGET_GENES	0.0001118	0.0034752	0.5384341	0.2695723	1.376237	959	FOXM1 C1GALT1 FOXA3 HJURP DNAH2 LRIG3 SLC9A2 PAIP1 AVIL TSFM CREB3L4 MRPL46 GPR35 ANKZF1 GTSE1 IFT122 UBE2Z NOL12 PLK1 NUF2 EFNA4 CENPA GPI WDR70 CDC6 PRKCA SLC35E3 LSR PHLDB3 CCNF ALDOC PLS1 MIS18A ZNF3 DZANK1 KRT15 SLC4A8 AGK LSM5 KAZALD1 TAMM41 IKBKE AARS2 SIPA1L3 TOP3B TJP3 CASP2 NEURL2 ZNF607 CISD1 NOP9 BBS1 PAQR4 CUL9 FBXW9 ZNF587B SAE1 LARS2 MAD1L1 DPCD MDFI RBM28 ASPHD1 WDHD1 ANKDD1B MORN1 MRPL3 ENTPD6 SLC4A11 WDR73 XXYLT1 CAPN12 ASB16 CSRNP2 ABCB9 MRPS11 B4GALT7 PKMYT1 OGFOD2 SYMPK NOL3 FBXO16 ALDOA ZNF587 ERCC2 NRG4 PIGO SRRM5 PPP1R37 DHRS13 DDX56 GEMIN4 CASP6 MSTO2P C9orf163 PPIL2 FRMD5 ANAPC5 DMKN WDR5B DTD1 ATP2A1 PLCH1 XRRA1 PHF12 ANKRD54 POLR3K CTXN1 CMTR1 PGBD2 TMEM182 DPH7 TNPO2 SEMA3A SNRPE HMGXB3 NOP2 ZNF623 RECQL4 SUSD4 PA2G4 RNASEH2A LZTR1 UNC45A ZNF692 NRGN MPI ZNF606 SNRNP25 DENND6B SPEF1 CAPS2 ZGPAT ARFRP1 ADNP MORC2-AS1 DNAJA3 ADAT1 EFCAB2 MBD4 XYLT2 COG7 MRPL11 HIRA TIGD6 FBXO4 ZNF544 KCNC3 PLEKHA8 JMJD4 POMT2 GAS2 PCDH9 ACAD10 LIN37 DNAJC11 ZNF768 KRBA2 SGSM3 TSEN54 ELMO3 POLD1 NUP85 FAM200A ZNF814 PEX10 ZBTB45 MAMSTR NADSYN1 LSM14B SLX4IP EPN1 DHRS1 STRN4 TIMM13 IARS2 RIN1 CHCHD1 TTLL3 FAHD1 HMGB3P22 PPP6R1 CDR2 SRRT ABCA7 DNMT3A METTL2B MRPL28 WDR83 RAI14 ZSWIM8 TMEM147 KPTN LRRC73 SNAP47 LANCL2 MRPL53 PYGO2 SLC35A3 SCYL3 HAX1 C1orf109 CYP2D6 HMCES RCC1 IGHMBP2 SLC1A5 PSMB4 RAP2B LRRC46 CORO2A RRP36 DDX55 MVP ZSCAN16 ARFGAP1 LRRC14 SPAG4 SH3D21 RER1 CAPN15 TSPAN10 CYTH2 CCNA2 RBM42 DBNL GRHL1 ANAPC2 AMDHD2 PDAP1 ZNF462 WDR4 CLUAP1 INO80E HOOK2 TRAPPC9 SEC13 PPFIA3 TRIP6 GTF3C5 TYSND1 MRPL21 SNX19 CHMP2A FAM118B RHOT2 SNORA14B MXD3 OSGEP PNKP LIF SRCAP ZMAT2 ALG1 NMT1 KIAA1522 NEIL1 SEPHS1 APEX1 BPNT1 MRPS27 SNRPC UBE2C NSUN7 TAF4 PTOV1 FUT10 NELFA UBTF SART1 PIGQ TPRN ATF7IP MUC1 RNF32 THAP3 MRPS26 C4orf46 SH3GL1 TMEM201 PLXNB1 LINC00888 FTSJ3 SS18L1 C12orf10 CORO1B ANKRD13D ACIN1 MFSD3 CYHR1 PRKAR1B SUMF2 UNC119 EIF2D ZNF513 CHMP6 WDR55 PSTPIP1 INPPL1 RFFL SHQ1 PPP1R13L VPS16 SRM GSK3A DPY19L3 SIGIRR MFSD9 MRPL12 RPL36 SPRED3 HUWE1 TRABD ATRIP ZNF579 LAMA5 RALGPS2 SMYD3 MARVELD2 ZNF77 CHD8 HDDC3 RNF40 AMH ECE1 MLLT3	up	**
MIR548D_3P	0.0001458	0.0042159	0.5188481	-0.2314493	-1.376215	518	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 PAG1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A SCP2 LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 ZBTB43 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 N4BP2L2 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA NABP1 SFPQ	down	**
MIR520B_3P_MIR520C_3P_MIR520E_3P	0.0017785	0.0242179	0.4550599	-0.2444791	-1.374305	286	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 SLC16A10 PLAG1 ARHGEF17 CFL2	down	*
MIR410_3P	0.0015866	0.0227674	0.4550599	-0.2449000	-1.372561	278	SMAD6 DPYSL2 RAPGEF2 PTPRB ZBTB34 TMEM170B CGNL1 BMPR2 NR3C1 MANBA MOB1B NUMB ARHGAP29 UBR3 PLXNA2 KLF10 KLF6 GLS SLC7A11 SRSF2 ANKRD29 BTG3 ATP6V1H SETD3 ROCK2 CCDC82 DGKE TBX4 ZSWIM6 SLC38A11 REST MAFG C9orf72 SMAD7 TBX5 KIAA0408 VEPH1 RUFY3 CNOT6L LIN7A SNX3 UFM1 SCEL PRDM11 DCTN6 ZNF548 UTRN NDNF TMTC1 CPEB4 ETS1 MN1 CNTN4 IPO7 SP3 SDHD COBLL1 RC3H1 LPCAT2 PDZD2 CXCL5 PREX2 LETM2 PBRM1 GLRA3 TEX14 BAZ2B TEC ZCCHC10 CNOT7 COL15A1 MICU3 PDE4B HACE1 FGF2 SLC34A2 RTN4 TIAM1 CXCR4 MFAP5 PSME4 RNF38 C21orf91 RORA NAA15 ZBTB44 STARD13 PSIP1 ACVR1C CHML SVIL	down	*
E2F5_TARGET_GENES	0.0001855	0.0050147	0.5188481	0.2686417	1.371554	968	PCSK6 TRIP13 FOXM1 FOXA3 CPLX2 CEP89 PARPBP FANCI GPT2 LYSMD1 TFAP2A RPGRIP1L CHEK2 CP BUB1B ZNF84 CENPF UBE2T PTPRN2 GBAP1 PBK KIF18B CHCHD6 NDC80 DEPDC1 DEPDC1B CDCA7 CDCA2 EFNA3 SMPD3 RACGAP1 IQGAP3 ANKZF1 CABIN1 POLE STIL DGCR8 PLK1 NUF2 CDCA8 AURKB CENPA ACAD9 ESPL1 TPX2 E2F3 CCNB2 STC2 MCM4 PRKCA MCM2 CA12 ZFYVE19 VILL RCCD1 ZWINT SMUG1 INTS1 RANBP1 TTLL4 OSBP2 MELK BTRC PODXL2 MKI67 BOD1 QTRT1 STAP2 KIF15 TRIM29 AP4M1 RHNO1 WASF1 TOP2A FBF1 ANO7 EME1 P4HTM SEZ6 SMARCAL1 MCM7 MAD1L1 E2F2 CENPW RRM2 CDCA5 PRKDC RHOBTB3 SGPL1 SDK1 RAD54L SBK1 MRPL27 ANKMY1 FANCD2 MCM3 LMNB1 CDC25C SEC61A1 ZNF785 YEATS2 BRD9 CHEK1 ZYG11A PEX26 THYN1 ORC6 HSF2BP SCAMP5 SRD5A3-AS1 CENPO MDM2 TRMT2A AKT2 LRRC61 BLM PHB ZNF605 CCDC136 SYMPK ALDOA TULP3 CNPY2 KNSTRN ZNF32 TTBK1 ZNF45 PPM1E CDK12 STON2 POLE2 EXOSC2 BIRC5 NUDT2 XRRA1 PHF12 SRCIN1 E2F1 UNG PSMB5 NEIL3 KCNK12 METTL3 SLC12A8 UCKL1 DIAPH3 CPXM1 ACVR1B DENND1A RANGAP1 CHCHD2 MPI ZNF687 ZNF354A DNAJC17 AKR1E2 CCZ1B VIPAS39 DLGAP5 C19orf44 DCAKD NADK2 MRGBP NFASC UBAC1 TSNAXIP1 ADNP ZNF133 LMNB2 XYLT2 CCDC151 KIF22 MRPL52 COX7C ZNF37A FBXO15 COPS7B UBE2Q1 TK1 KCNC3 ZNF239 ARHGAP5-AS1 CCDC146 GINS2 ANP32E TSSK3 KIF20B LAMTOR2 TM9SF4 SAP30 SLC4A2 FHL2 ACSL6 MAGOHB CEP128 CCDC159 ATAD5 AAMP ATP13A1 TCEA2 SLX4IP SASS6 UBQLN4 CENPV ACBD5 NFXL1 TSTA3 CKAP5 UBE2O KCNB1 NPRL3 DUS1L MADCAM1 CDK5RAP2 CLINT1 MCM6 MGME1 EML6 PPCDC CENPT NOSIP MCM5 GNG4 DDX23 NSD1 RTEL1-TNFRSF6B SRSF1 C1orf109 NFE2 STMN3 DOLPP1 SUGP1 SH3BP5L ATAD2 PATZ1 FARSA AP2S1 ADORA3 TSC2 CCNA2 SMARCA4 RCN3 GRHL1 RTEL1 CANT1 PLSCR2 MRPS25 SHCBP1 SCNM1 LINC00964 DTNB GTPBP2 ZNF436 USP39 ACSF3 CCDC88B MLLT6 RAD51 STK25 TOMM40L FBXW11 ARHGAP5 ST20	up	**
HOXB6_TARGET_GENES	0.0015226	0.0224541	0.4550599	0.2758922	1.371499	520	ATP10B FOXA3 RPGRIP1L CCDC34 TIMELESS SEMA4B NDC80 C12orf66 CDK4 IFT122 HILPDA NABP2 PCLO AP1S1 TOMM34 CEP70 EFNA4 GPI GAPDH RBBP8 HOXB7 SLC35E3 PRC1 XRCC2 KAZALD1 FAM220A NME1 HAUS5 WDR62 RSPH1 TTLL4 ZNF862 NLE1 SYTL2 SPAG16 TP53BP1 PCCB TSGA10 TIGD4 LGMN TOP2A EME1 C1orf226 SAE1 CENPW CDNF SETDB1 CCDC114 NME9 MRPL27 WDR73 B3GNTL1 WDR60 IFT172 TRMT61B MDM2 TBC1D8 PPP5C SYMPK C4orf47 SRRM5 TULP3 POLN C12orf75 RNPC3 GMNN SMG9 STAT2 MKRN1 ZNF584 ANKRD26 CNOT11 THAP8 GOLGA5 LRRC56 CHCHD3 ELMOD3 ZSCAN21 EDEM3 RHOC TUBG1 C19orf47 ENTPD3-AS1 GSS DNAJA3 NMRAL1 MAN1B1 MBD4 CCDC151 ZMAT5 TRIM37 COX7C FBXO15 CSNK1G1 HIP1R FZR1 PDRG1 MAPK10 XPR1 SLC4A2 DNMBP C15orf41 CDK13 MAGOHB ZBTB45 CNDP2 P4HA1 UBE2O ERBB3 CCDC30 EFHC1 HMGB3P22 FITM2 SRRT ABCA7 RPPH1 WDR35 ZRANB3 UIMC1 SRSF1 HOXA-AS3 AATF EXOSC5 LSM4 EIF3K U2AF2 CEP152 MST1P2 PRMT5 GADD45G NME1-NME2 B9D1 MAP3K14 ULK4 ZNF195 MRPL55 ABCF2 PCSK5 UQCRC1 N6AMT1 TPGS2 PPFIA3 KIAA0825 CHMP2A ACP1 CDK5	up	*
MIR373_3P	0.0009641	0.0158456	0.4772708	-0.2450602	-1.370552	280	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST ANO6 MIER3 TRIM36 IRF2 ZFYVE26 PLAG1 ARHGEF17 CFL2	down	*
MIR10399_5P	0.0016228	0.0229350	0.4550599	-0.2389898	-1.368472	316	ZC3H12C CPEB2 SNX10 EMP2 ST6GALNAC3 PTPRB RASAL2 MS4A15 QKI BMPR2 TGFBR3 MOB1B RCHY1 CNST TRA2B RAB33B BZW1 NLK PRSS12 EIF4E LHX6 MPHOSPH6 SPTBN1 MAPK8IP1 PDE4D ROCK2 TLE4 FOXO1 PPP6R3 KLF4 ITM2B PEG3 PLEKHM3 ANKRD10 GAPVD1 CYP20A1 RECK UBE2B CAPZA2 CCSER2 PRICKLE2 IKZF5 SIAH1 TGFB2 METAP1 YBX1 SGK1 KIF13A PHACTR2 NEK7 INPP5B SH3BP5 CNTN4 EEA1 HSPA13 CREB1 CTTNBP2 NECAB1 HIVEP2 MAPK8 NAA16 DCK PDS5B RSBN1L TMEM230 MYOCD RIMKLB KAT2B ABI3BP ATAD2B INO80D RNF138 ABL2 CTTNBP2NL SFT2D1 NT5C2 RAB5A TMOD2 ARIH1 PTCH1 PSME4 SRSF10 RASSF8 DOCK10 SCAI FAM126B CAMSAP2 CCND3 SHISA6 SPATA13 EIF4G2 ABI1 REEP1 PLAG1 PEX14 TBPL1 GJC1 NR4A2 MAPK1 CTDSPL2 SV2B SPTY2D1 SGIP1 HMGB1 CUL2 CRIPT FAM218A PNRC2 SLC23A2	down	*
MIR520A_3P	0.0024513	0.0307092	0.4317077	-0.2427409	-1.368309	288	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 SLC16A10 PLAG1 ARHGEF17 CFL2	down	*
MIR4699_3P	0.0006042	0.0117400	0.4772708	-0.2354898	-1.368272	404	SLC31A2 SASH1 DLC1 USP12 GREB1 KCNA2 ZC3H12C PTPRB ZBTB34 TMEM170B SH2D3C TXNL1 CALCRL PLEKHA1 ARL8B MEF2A KBTBD3 FBXO3 PPM1D KCNAB1 UBR3 PTPRM TTL RAPGEF4 ASAH1 PLXNA2 C1orf21 NLK PAQR3 HLX DACH1 FOXJ3 ADRB2 TMEM41B TFEC RAB14 GPR4 RAB12 PIP5K1B PXDC1 PRKD3 ZFAND5 NFKB1 PNRC1 ARL4A N4BP2L1 GNAQ TM9SF2 PDE1C CNOT6L TGFB2 STK24 SACM1L RBM39 SLC8A1 FMNL2 ELF1 BCAR3 GABARAPL2 HSD17B13 PIKFYVE C20orf194 ADRA1A BMP3 APBB2 TBC1D12 DHX15 SKIL EEA1 LSM1 TUBGCP3 CGGBP1 ZNF407 OCIAD1 PELI1 PTP4A1 ING3 AZIN1 DDHD2 VAV3 STRN PHF3 ABHD13 RSBN1L MPV17L CNOT7 MAP3K2 STX12 CRY1 ARPP19 INO80D SLC35D2 INTS6 PDLIM5 VGF ARHGAP18 USH2A MEX3C NPAT KIT SCAI FAM126B KIF1B SAMSN1 RORA NRG1 RHOT1 C1orf52 FCRL1 RABGEF1 DMXL2 STARD13 DUSP6 EXPH5 MAMDC2 CMPK1 SLC38A2 NOG TBC1D23 KCNJ1 CSNK1G3 ADAMTSL3 PIK3CG IFIT5 SGIP1 UNC50 MTSS1 ANGPT2 SGPP1 TMEM220 POLR2B MAP3K1 FASTKD5 CCPG1 NKTR RAB11FIP2 CLVS1 MPDZ ARGLU1 MSC SKP1 LARP7 IREB2 EMP1 CBFB ZCCHC14	down	*
MIR20A_5P	0.0001344	0.0039660	0.5188481	-0.2265521	-1.368118	577	RAB11FIP1 EREG TMEM100 ABHD5 FGD5 SOWAHC ZC3H12C DPYSL2 ST6GALNAC3 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 C3orf70 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 CRK ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 MSR1 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 VASP ZADH2 STK17B FBXL3 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 CLIP4 PAFAH1B1 KPNA3 NCKAP5 TANC1 CNOT6L CNRIP1 VCPKMT ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PHLPP2 PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 UBE2D1 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	**
TFEB_TARGET_GENES	0.0000002	0.0000277	0.6901325	-0.2191156	-1.368034	1085	SMAD6 WEE1 SEMA6B EPAS1 ACP5 ARHGAP31 LPIN2 MRPS18C HMOX1 SWAP70 CXCL16 MCOLN1 TSPAN4 DLC1 ADTRP HHEX ROBO4 FABP4 ATXN3 SLC51B USHBP1 SPNS1 RAPGEF2 PTP4A2P2 TRPV2 SLC6A12 CDH5 INSIG1 SH2D3C TXNL1 CCRL2 BACH1 ST3GAL6 CORO1C ARIH2OS QKI ZCCHC2 ARL8B NUDT9 DYRK1A CASP12 VAPA TSHZ1 LAMP1 CD22 TGFBR2 NFATC3 HPS5 TRIB1 RCHY1 CCNL1 ERG EDEM1 ATP2B1 RRAGC ASAP1 PTPRM MCTP1 SIRPB2 MALAT1 HECW2 LMNA LATS2 SDE2 ITGA5 ZNF503 PICALM ANPEP KLF6 CAMTA1 EIF4E FOXJ3 JAM3 SRSF2 ISLR2 TNS1 GRN LAMTOR3 SPRY2 ZEB1 ARHGEF2 RNU4-9P UBE2D3 ATP6V1H MTHFR MYCT1 TUBB6 GPM6A ATP6V1B2 CPED1 CYBRD1 TBC1D9 ARRB1 MOAP1 DUSP3 PPT1 CCDC82 SORBS1 DENND6A LIMS1 FAM124B PKD1L1 KLF4 RUNX1T1 DAB2 GAA PARVB SLC7A8 ZADH2 MAP1LC3B SDAD1P1 ATP6V1D MAFG TPP1 LINC00702 LY96 SNIP1 CTSD SSH1 DOCK9 ITGAX NR1D2 CXCL2 AXL ID2 TLR4 ARAP3 UBE2B PLEKHB2 DUSP1 ALOX5AP MFSD11 ELK3 CUL5 LINC00346 SLC25A32 CLIP4 SLC6A6 SMNDC1 ZNRF3-AS1 PRICKLE2-AS3 MAPRE2 CNRIP1 HEXB SNRPGP5 NRROS TBC1D5 PRCP SLC25A33 ZCWPW1 RBPJ CREBRF GZF1 HM13-AS1 CREM PHTF2 NSMAF MED28 SGK1 CAHM ATP6V0E1P1 PIKFYVE HCFC2 SEC14L1 FAM189A2 SH3BP5 RAB31 NSMCE2 CELF1 ATP6V0B CARD8 OSTM1 HELQ VPS26A JAK1 RHOJ TMEM251 SNX2 SKIL LINC00607 GRASP SIGLEC15 ATP13A3 GTDC1 CAP1 TRAK2 UVRAG EGLN2 APH1B CLN3 RALB WDFY4 TPRA1 IP6K1 NDUFV2 CD34 CDK14 BLOC1S6 SLC3A2 ATP6V0D1 RNASEK CACYBP CD164 ZNF669 C22orf34 NOP10 ATG3 ICAM2 MYL12A HNRNPD CPA3 ZNF521 EHD1 TCF4 PHF3 ZBTB1 SMCR8 DCK OSGIN1 PDE12 MIR23A ATP6V1A KHDRBS1 IRS2 C16orf72 RELL1 ATP6V0C HBP1 PLSCR4 FAXDC2 PPP3R1 EXOC1 BRI3 FCGRT ANKRD12 NPTN MFNG RIMKLB ACTN2 LTBP1 KIF17 CLCN6 CLEC2B PPID PET117 TCTEX1D4 ALKBH3-AS1 GEM ICAM1 BNIP3L LDLRAD4 TRAC PCM1 ABL2 FKBP1A FAM167B ELP2 ZNF438 MGAT2 RAB5A ACAP2 TEX10 HSP90AA1 THAP6 EXD3 TRAPPC8 EPHA4 FBXO30 SIK3 ZBTB25 PTCH1 AMZ2P1 SDAD1 OSER1 VSIG10 TBCEL FNBP4 STK4 RAPGEF3 JMJD1C GTF2F2 MAFK EDN1 MAGI2-AS3 MTUS1 DUSP7 TMCC3 DAZAP2 RHOT1 MT2A PSMD9 CNOT8 MAPKAP1 ATF4 LINC00884 BMI1 DNAJB5 FEZ2 HSDL1 ZBTB40 SPHK1	down	***
GLI4_TARGET_GENES	0.0005748	0.0114071	0.4772708	0.2719181	1.367837	683	TF FOXM1 SLCO5A1 EYA1 RUVBL1 TICRR DNAH2 FBXW8 NUP107 DOC2A C17orf75 PSPH TSFM SLC25A21 NOL12 TTC26 IRX6 NUF2 WDR70 ZNF221 GRHL3 DTX3 CCT6A ZNF3 AGK NME1 TOP3B WDR62 TMEM41A ZNF391 C9orf116 SLFN5 AP4M1 RHNO1 CCDC77 GTPBP3 MCM7 SPEF2 RBM28 MRPL3 ANKRD13B CCDC58 PFN2 TARS2 FAM162A OAZ3 EME2 TRMT61B RAB13 RAD51AP1 THAP10 TMEM63A B4GALT7 GEMIN7 COMMD4 FLNB ALDOA TULP3 R3HDM2 OSBPL7 NRSN2 DDX51 ANAPC5 SLC39A11 CDK1 HDGF CDK12 SSBP1 ZSCAN25 STX18 TRIM2 DGAT2 MRPS2 DHX33 ENPP3 KLHDC9 KRBA1 TSPAN31 ZNF775 TMEM79 SMO NAPEPLD HMGXB3 ZNF827 VPS72 CENPP WDR24 ABHD4 ANXA2R KANSL1-AS1 PIAS3 GOLGA3 ZSCAN9 ACBD6 CAPS2 ILF2 SMG5 ARHGEF16 ZNF233 GALK2 ATP6V0E2 MTOR MRPS34 C19orf12 HIRA ARF5 DNM1 COPS7B FBXO4 CASP7 JMJD4 MLEC HECTD1 MTND5P11 STX18-AS1 GFM2 ZNF282 KDM3B FAM207A C12orf73 FAM200A PRRG2 MT-TH ZBTB45 NIF3L1 CCDC137 KDM3A BAZ2A EFCAB7 LSG1 PSMB3 VPS25 STOML2 AHCYL1 ZNF616 DUS1L FAHD1 PPP6R1 FANCM PEX5 CACNG8 WDR83 NOSIP NOC4L NMNAT1 ANKS3 SNAP47 LANCL2 NDUFS7 POLR3E IGHMBP2 DDX55 MST1P2 ZNF580 NME1-NME2 PRPF18 TSPAN10 BANF1 POLR3B CCDC167 STAT6 CDK5RAP1 PRPF31 BMS1 TRIP4 SEC13 MARK4 ECHS1 GTF3C5 SUPT3H SAMD4B MRPL9 SRP9 MRPL21 LINC00240 RHOT2 AGBL5 TMEM101 AURKAIP1 LZTS3 SNUPN CASC2 LRP5L ZNF131 TCF3 ZNF205 TRUB1 MCF2L2 PIGL DCDC1 FUT10 MRPL48 ZER1 MOK ANKRD13D SLC33A1 KIAA0586 EIF2D FGFBP3 SETD1A ANO8 MED22 MUS81 MAN2C1 C12orf43 PARL RPL36 NOXA1 SFT2D2 ZC3HC1 RBL1 ZNF771 CYB5RL RDH14 TNPO3 OPA1 ZNF579 NSL1 EDC4 MCEE TLE2 SLC4A1AP COQ5 TSC22D4 TLCD1 TEFM MTR IGDCC4 IMP3 MBD6 TIPIN MTF2 TIMM9 PSMD3 STEAP2 RPL41 BNIP1 DHPS DDX49 SLC44A1 PRKAB2 CACNA1A IPO4 METTL9 ZNF302 ACOT7 HNRNPA1 MPLKIP NUDT19 KLHL20 CLTC DNAJC2 SLC39A3 TSEN15 DHX30 CLPB RFC3 AJUBA NVL MPP2 JRK IFT74 BCKDHA REXO4 COX16 CIZ1 ATXN2L CUEDC2 KANSL1 DDX19A	up	*
ADA2_TARGET_GENES	0.0007216	0.0133937	0.4772708	0.2694129	1.363962	756	HMGA2 MNX1 CPLX2 RUVBL1 FBXW8 PDCD6 NUP107 C17orf75 ZFHX4 DDIT4 NUDCD3 THEM4 ECE2 ZFP62 NOL12 TENM2 EIF2B5 TTC26 NUF2 E2F3 MCM4 TIGD1 NCAPD2 COQ3 CDK5RAP3 SPDL1 AGK UQCC1 LSM5 FAM220A NME1 TOP3B TMEM41A ZNF391 CHAF1A BBS1 ZNF850 AP4M1 RFXANK PMS2P4 ATR GTPBP3 TMEM132A MCM7 RBM28 MRPL3 SLC4A11 SBK1 EMG1 TARS2 YEATS2 RNFT2 EME2 BMS1P1 GET4 ABCB9 THAP10 B4GALT7 GEMIN7 EEFSEC SPAG8 OGFOD2 INPP4B MTG1 ALG3 MNAT1 KNSTRN ANAPC5 CTDSP2 SSBP1 DTD1 TESC ADAP1 STX18 MAP3K10 MCAT MKRN1 WDR31 AP5Z1 DHX33 ENPP3 KLHDC9 DPH7 ANAPC7 POLR1C PSMG3 TTC23L POC1B SF3B3 TNRC18 SEMA3A MTBP HMGXB3 NOP2 CCDC57 ZNF827 MAD2L2 ZNF623 CENPP WDR24 YEATS2-AS1 DNAJC7 CHCHD2 GOLGA3 ZSCAN9 ACBD6 SLC35C2 NDUFA11 GALK2 TRMU MTOR TACC3 MRPS34 YIPF3 PLEKHG3 KIF22 HIRA TIGD6 COPS7B ARL6IP4 DBN1 JMJD4 MLEC STX18-AS1 ZNF768 GFM2 COG4 TSEN54 FAM207A C12orf73 PRRG2 CCDC159 ZBTB45 CABLES2 NIF3L1 BAZ2A PPIEL PROX1 SH2B1 EFCAB7 MDGA1 LSG1 VPS25 STOML2 DUS1L FBXO22 NAT8L FANCM CACNG8 WDR83 CELF4 NOSIP NMNAT1 TDP1 SNRPD1 SNAP47 EIF3D SLC35A3 STMN3 NDUFS7 MRPL51 YIPF2 IGHMBP2 DDX55 ZNF580 NME1-NME2 PRPF18 BCL9 TSPAN10 ZNF195 BANF1 RTEL1 POLR3B AMDHD2 TUBGCP4 CDK5RAP1 ZNF462 ACSF3 BMS1 ZNF384 TRIP4 SEC13 RNF123 PFKM GRAMD1B MARK4 GTF3C5 ZSCAN22 MRPL21 KIAA0825 AIFM2 VPS9D1 TMEM101 AURKAIP1 OSGEP POLR1B BCL6 ZSCAN29 EIF4G1 NDOR1 ZNF205 APEX1 PIGL DCDC1 BCAT2 NELFA PIGQ ZSCAN20 MRPL48 ZER1 TRUB2 HEMK1 SLC33A1 KIAA0586 INO80B EIF2D NUMBL FGFBP3 KLK10 MED22 MAN2C1 SPHK2 VPS16 GSK3A C4orf48 FAM120A DPY19L3 NELFB EIF2B1 MST1 RPL36 NOXA1 LOXL1-AS1 ZC3HC1 SPRED3 ZNF276 APBA3 TNPO3 TRABD OPA1 ZNF579 NSL1 EDC4 MECOM MCEE SLC4A1AP STARD10 TSC22D4 MTMR4 TEFM ZNF682 PGAM5 SLC20A2 MTR DLGAP4 C1orf194	up	*
HOXC6_TARGET_GENES	0.0002524	0.0064942	0.4984931	0.2668229	1.362505	953	HMGA2 ATP10B PPM1H SYT8 DDX11 FOXM1 VWDE MYCBPAP LAD1 CEP89 PARPBP BDH1 AP3B2 ZMYND8 DDX11-AS1 CIB2 DDIT4 NUDCD3 NDC80 PLEKHH1 DEPDC1B METTL1 ZFHX2 CDK4 XKR9 HILPDA UBE2Z ANLN FLAD1 CEP70 YEATS4 TPX2 GAPDH FIGNL1 THTPA AGR2 LSR PMS2 ACY1 KIAA0895 VILL XPOT NCAPD2 ZWINT LRRC27 HAUS5 ZSCAN2 BZW2 C1orf220 NDUFB8 ZNF74 LAMC2 RPL39L PAQR4 SLFN5 F2RL1 RNF216P1 TRIM29 AP4M1 KNTC1 WASF1 CLHC1 CCDC77 TMEM184A CENPL APOL1 CBX3 TMEM177 SMARCAL1 MCM7 ZNF860 ANKRD19P CDCA5 WDHD1 PKM AIMP2 WDR60 LIG1 SIDT1 SPINT1 IFT172 PEX26 CENPO COX19 SLC25A39 AKT2 LRRC61 PKMYT1 ETFA FDXR COMMD4 NOL3 C2CD3 ERCC2 ALG3 TFCP2 TRIT1 RNF216 MSTO2P NCAPG2 FASTK NUSAP1 TMEM106C ANAPC5 ING4 SSBP1 CENPJ ANKRD54 AAGAB POC5 STX18 KCTD13 CMTR1 RNF181 ACTR3C TRIM41 LARP1 PDK1 CPNE1 POLR1C PSMG3 TNPO2 TRIM7 LINC00649 USP42 SF3B3 ATAD3A NOP2 RNASEH2A LZTR1 UBN2 ZNF692 MAP3K14-AS1 MYO19 SLC35C2 TAPBPL YDJC GSS ADAT1 ALDH7A1 NMRAL1 SNRPA RAD9A YIPF3 ARHGAP32 COG2 ZMAT5 IQCG COX7C FBXO15 ZNRF2P1 ENAH CENPQ MSRB2 CSNK1G1 MEGF8 OS9 MRPL4 PKP4 ACAD10 AGPAT5 ITFG2 MAPK10 STX18-AS1 LRWD1 NDUFA13 TRIM32 CD27-AS1 COG4 SYNGAP1 IQCH CDK13 ATAD5 PPME1 RBM33 TMEM232 NAIF1 YARS2 NIF3L1 RAD50 CCDC137 KDM3A BAZ2A SASS6 RNF187 CLDN12 LIMA1 CPSF4 TMEM106B CA11 EFHC1 RRP9 ALKBH4 PPP6R1 TRIM56 GID8 EML6 NOB1 LANCL2 CACNB3 ADD3 ZBTB9 MRPL51 LINC00471 WDR27 LRRC46 WDYHV1 SH3TC2 DDX55 ATAD2 ALG8 ZNF622 SUV39H2 MICAL3 AMN1 ZNF212 SMARCA4 NTMT1 PRR11 HDLBP GABPB1-AS1 GTF3C2 DDX54 SNRPD2 POLR3B GTPBP2 PDAP1 ICK INO80E OSBPL10 TMEM44 RAD51 ZWILCH KCTD21-AS1 PPP6R2 GTF3C5 SUPT3H ZNF121 SNRNP200 FAM83E NUBPL UBAP2L ZNF131 PNKP RELL2 XPC ANKMY2 DNAJC14 DNAJC10 ALG1 GGCX GDPGP1 TMEM9B-AS1 RANBP3 MRPS27 CYSTM1 ARMC10 RAD1 DDB2 RABL6 NLGN1 PIAS4 BRSK2 FAM222B PPP1R14B PTPN13 ACTR5 BRIX1 SETD5 RAD51-AS1 ALKBH2 CLNS1A RNF14 FAM47E TOMM7 INO80B ZNF740 RPL23A SETD1A WDR55 MED22 MUS81 MBTD1 DEPDC4 PPP1R13L METTL4 SH3RF2 UTP18 CRAT ZNF598 NIT1 TMEM259 ZC3HC1 RBL1 APRT PPP2R5E HINT1 FOXP2 PSMB10 CES2 SDHAF1 USP35 GGA1 TOMM40 SNHG17 MAD2L1BP SLC4A1AP TYMP TLCD1 PIWIL4 MRPL45P2 CRYZ TEFM CCDC6 ARFIP2 MTR CXXC1 SLC27A5 TTPAL CACTIN IMP3 MAP3K5 ZNF524 HDAC3 GGA3 ELL3 HNRNPAB TIPIN MTF2 TTC13 CDH24 PC MCCC1 ARHGEF26-AS1 UVSSA SWSAP1 HENMT1 PAN2 SAP30L DHPS DDX49 PRKAB2 SLC12A9 MAEA SCAND2P NUP37 KIF3A PAWR PACRG CABYR PTPN23 ZNF691 IPO4 ZNF839 XRCC6 OIP5 HM13 COA6 ZNF473 SKA2 ABCB8 C1orf43 WDR12 VRK3	up	**
MIR4307	0.0023106	0.0293220	0.4317077	-0.2376775	-1.361594	337	TRIM71 HSPA12B COL25A1 PHACTR1 PTP4A2 BTNL9 RUNDC3B ARRDC4 TMEM170B CGNL1 FLVCR2 OTUD4 TEX2 ZEB2 KCNAB1 CNST RAB33B HIPK3 CAV2 SLAIN2 RGCC SRSF2 PDE4D TBX4 PPM1K LIMS1 LIN7C FAM76A SETD9 SLC12A4 ROCK1 UBQLN1 SSH1 GPR85 CDS2 HNRNPUL2 CTBS AQP4 CYP20A1 CPT1A CMTM6 EFR3A LIN7A ZDHHC20 LIN54 SACM1L SPIN1 VPS37A PHTF2 PHACTR2 USO1 PTGER4 IPO7 ENPP4 GLIPR1 CD83 MBNL2 IDS CGGBP1 HIVEP2 NAA16 WNT11 CHORDC1 EPHA3 DDHD2 LSM6 PDS5B VAMP4 CNOT7 PCDH17 COL15A1 ANKRD12 NPTN RIMKLB GPR18 EMC4 INO80D PET117 GEM YAF2 C22orf23 DCTN4 ACAP2 TMOD2 HSPA8 TDRP MEGF9 G3BP2 ZDHHC21 STAM2 BCAT1 JMJD1C SCAI	down	*
MIR548BB_3P	0.0002501	0.0064793	0.4984931	-0.2286493	-1.360833	513	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 ZBTB43 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 CPEB4 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA	down	**
MIR548F_3P	0.0007312	0.0135054	0.4772708	-0.2334259	-1.360749	416	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP TMED5 MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 PIKFYVE RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	*
MIR153_5P	0.0000081	0.0005140	0.5933255	-0.2147201	-1.360658	866	SLC24A4 EREG AKAP5 FOXF1 OSBPL1A RBMS2 ZC3H12C ATXN3 CLDND1 PTPRB TTC7B GPC5 ARRDC4 TMEM170B LPL OTUD1 LMO2 BACH1 DDX6 NEDD4L THAP2 QKI GPCPD1 ZCCHC2 PLEKHA1 C5AR1 MEF2A KBTBD3 RXFP1 NEDD9 VAPA TSHZ1 PSMD5 CD22 MOB1B FAM49A ACER3 PDCL ZEB2 ANXA1 NCEH1 B3GNT5 UBL3 SLC36A4 SLC25A17 ENTPD1 NAAA RAB33B BTG2 SERINC1 ZNF503 MS4A14 GLS CAV2 CAMTA1 DACH1 SLAIN2 PPP3CA AKT3 TMEM41B CWC22 PRDM16 TLE4 DGKE KCNMA1 DENND6A LIMS1 ACSL3 KLF4 PAQR5 RUNX1T1 RRM2B ZADH2 TMED5 STX3 GRK5 FBXL3 MYRIP PDE8A ATL3 C1QTNF7 MGAT4A C4orf33 RBMS1 NR1D2 M6PR CCSER2 DNTTIP2 ZMPSTE24 GCA DSE EXOSC8 CUL5 PEAK1 SLC6A6 KIAA0408 BCLAF1 NUS1 GNAI2 PDE1C TBC1D4 NCKAP5 CDKN2AIP ZDHHC20 PIAS1 TDRD7 C2orf69 SRGAP2C RBM39 GPBP1 RBPJ ETF1 PRKRA DCP1A SCEL ID4 PDIK1L SYNPO2 LRRTM2 PLGLB1 COPS2 EBF2 NEK7 RAB8B PIKFYVE PDCD6IP RGS18 NECAP1 TMTC1 MITF NOTCH1 HMBOX1 GABPA ADRA1A OSBPL9 BMP3 MSRB3 MAP4K4 CNTN4 CCDC50 EPC1 APBB2 IPO7 SNX2 FBXO11 SKIL EEA1 PNPLA8 SP3 PCGF5 THUMPD1 FRYL CREB1 COBLL1 LPCAT2 PDZD2 ZNRF3 PREX2 SMIM20 APH1B SNRK CELF2 AGFG1 SLC25A24 RHOQ PELI1 AGPS CALM1 YTHDF3 EPHA3 DDHD2 CHRAC1 DCK VAMP4 FEM1B PDE12 SH3RF3 CDC37L1 TRGC1 GNAI1 IFNAR1 EWSR1 MAP3K2 RELL1 PCDH17 ATXN1 APLP2 MYOCD TOB1 WBP2 RIMKLB ZNF267 INO80D SYT11 AMD1 BNIP3L RNF138 MIER1 CTTNBP2NL EGFL7 LRP12 RIPK2 CYP2U1 ALDH2 USH2A IPO5 POLR2M SRSF10 KPNA4 RBMS3 TBCEL COMMD8 NHLRC3 STK4 C7orf31 BCAT1 RASSF8 MARC1 NALCN ARPC5 SCAI SKI CHCHD7 SNAP29 FAM126B CNTNAP3B NR3C2 MAPKAP1 DUT SPOPL PURB ENY2 GRPEL1 HPCAL4	down	***
MIR6083	0.0034682	0.0384907	0.4317077	-0.2493922	-1.360130	222	SMAD6 FOXF1 GCSAML C18orf32 KCTD9 HSD17B11 CCDC88A SEC22C QKI MANBA SGMS2 RANBP9 SLC7A11 MED26 SETD3 TMEM38B ATP10A CPED1 ROCK2 TBX4 ZFAND5 TMED5 NPR3 RNF139 SMAD7 CDKN2AIP ACTR2 PIAS1 HCK PPIL4 PRDM11 PDIK1L SENP3 NEK7 ESD RNF141 CNTN3 PPA2 SHOC2 RABGAP1 PTGER4 IPO7 SP3 ACKR3 PI4K2B ATL2 SNX1 FSD1L NIPSNAP3B SLC35F1 FEM1B CDC37L1 KHDRBS1 MAP3K2 ANKRD13A CRY1 PCCA PRDM8 INO80D IQSEC1 CXCR4 ARL14EP CREBBP STK4 MAFK SCUBE1 CHCHD7 RORA FAM13C	down	*
ZSCAN31_TARGET_GENES	0.0009593	0.0158375	0.4772708	0.2684553	1.359449	769	PDE11A KIF20A GPR89A DNAH2 ZDHHC4 NUP107 ABCA17P DOC2A C17orf75 FBXO27 PDCD2L ZFP62 HILPDA SDHAP3 NABP2 TTC26 NUF2 PTTG1 TIGD1 LSR DNAH14 ZNF107 MPPED2 DCTN2 WDR90 NME1 GOLPH3L MANSC1 ASAH2B ITGA2 BZW2 ZNF607 NUDT1 STRA6 SMARCC1 KIF23 C9orf116 CUL7 LINC00665 PAFAH1B3 CCDC77 EME1 MYO10 VANGL1 ATR GTPBP3 WDR78 RSRC1 COASY PDCD5 AMACR ZNF146 MRPL27 PHKG2 FANCD2 EMG1 TARS2 WDR60 OAZ3 POLR3C EME2 TRMT61B ACSF2 CSRNP2 THAP10 EEFSEC PHB COMMD4 MBOAT1 MNAT1 SLC25A10 KCNJ2 SKP2 TTBK1 NRSN2 CDKN2C TMEM106C SUPT5H CBX5 SRRM2-AS1 KCTD7 ZNF260 ZSCAN25 GMNN POLR3K STX18 VANGL2 KCTD13 DNA2 MRPS2 SLC25A13 FAM98C ENPP3 KLHDC9 TMEM79 TTC23L NAPEPLD UCKL1 CENPP WDR24 SUSD4 STK11 C3orf67 SNRNP25 GIPC1 ACBD6 GNPAT SATB2 SMG5 NDUFA11 FAM47E-STBD1 GALK2 TRMU MTOR NMRAL1 RBFOX3 AARSD1 DHRS4-AS1 MRPS34 LLGL2 CCDC151 C19orf12 PIGG HIRA COPS7B FBXO4 ZNF544 C1orf131 JMJD4 MLEC LINC00662 STX18-AS1 TMEM186 ASNS S100A13 FAM207A PRRG2 ZBTB45 SCNN1G TRAF3IP1 CLTB CABLES2 CDC7 NIF3L1 PROCA1 EFCAB7 TIMM13 CPSF4 BRD8 EFCAB10 VPS25 CCDC30 ZNF428 DUS1L FBXO22 MRPS23 PPP6R1 ZNF223 C16orf58 RAI14 NOSIP TMEM147 ZNF783 NMNAT1 HEATR1 SNRPD1 SIRT5 RABEPK SNAP47 ADD3 C1orf109 GINS3 NHSL1 NDUFS7 POLR2I YIPF2 ETV6 SUOX IGHMBP2 ZNF780A DDX55 MST1P2 COPZ1 NME1-NME2 B9D1 MCRS1 NCDN ZNF195 HEATR5A DENR POLR3B PCBD2 CDK5RAP1 VPS33B TRIP4 FBXW11 PFKM PPP6R2 COPA MRPL9 MRPL21 SNRNP200 CHD3 LINC00240 RHOT2 TMEM101 NUBPL TBCB AURKAIP1 ZNF793 ANKMY2 ADRM1	up	*
MIR520D_5P	0.0000085	0.0005164	0.5933255	-0.2195018	-1.359373	810	AJAP1 MGAT3 SC5D IL1A SGK3 TAL1 SECISBP2L CPEB2 LTA4H SLC16A4 PTPRE LIPA PTPRB ZBTB34 TMEM170B BDNF PLEKHF2 MED4 DDX6 QKI DYRK1A CDC42 FBXO3 GNPTAB TSHZ1 TET2 NFATC3 SPCS3 HEG1 TMX4 ZEB2 TXNIP ARHGAP29 WWC2 ATP2B1 CACNA2D2 LATS2 RAB33B BZW1 MAP3K8 RANBP9 COX18 KLF6 RNF182 GLS CAV2 PTX3 CAMTA1 ADIPOR1 EIF4E DACH1 FOXJ3 PPP3CA RGCC SRSF2 LHX6 HNRNPDL TFEC HNRNPU TCF7L2 UBE2D3 TFRC RAB14 ZYG11B GPM6A ZMIZ1 PTPN12 MSR1 TLE4 RAB12 FOXO1 DGKE SCP2 BNIP2 TCP11L2 ACSL3 KLF4 FAM76A REST PRKD3 DRAM1 TJP1 SEC24B C1QTNF7 PER2 LRRC40 IRAK2 CYP20A1 PNRC1 CEP57 ZBTB43 CLK4 UBE2B MBD2 RAP1GDS1 SLC6A6 PRICKLE2 OXSR1 UBASH3B PAFAH1B1 BCLAF1 SMNDC1 FAM76B AKIRIN1 EFR3A CNOT6L RSRC2 CNRIP1 NCOA1 SIAH1 FAM102B USP25 RBM39 GPBP1 CREBRF PRKRA SCEL ID4 ELF1 PDIK1L CREM YBX1 DDHD1 SGK1 HSD17B13 EBF2 HCFC2 PPP6C SERPINB8 JUN ARL5B MITF STAT4 GABPA GLUD1 DDX17 C11orf58 BMP3 MSRB3 HSPA1B OSTM1 EPC1 SKIL ENPP4 SP3 ACKR3 CREB1 ZNRF3 PREX2 CGGBP1 MEAF6 AGFG1 CTTNBP2 PELI1 AZI2 HIVEP2 USP7 PPTC7 MAPK8 PKIA RIN2 TTBK2 BTBD7 EPHA3 SORT1 GOLGA8R VAV3 TCF4 ATG2B SERPINB1 VAMP4 RSBN1L SBF2 GOLGA8H ZC3H12D ATXN1 CSDE1 PPP3R1 GNB4 GNA13 KAT2B ADAM10 PDE4B CALB1 ETS2 MBNL1 ATAD2B ARPP19 SMAD2 INO80D RNF138 SESN1 INTS6 SLC34A2 ZNF583 CEBPD LRP12 TRAPPC8 TAB2 FBXO30 ARIH1 MEGF9 HNRNPK G3BP2 GRIN3A SRSF10 KPNA4 VSIG10 NPAT TTC28 DOCK10 SCAI FAM126B KIF1B RORA FAM13C DOCK4 RHOT1 SFPQ GSPT1 CNOT8 WDFY3 PUM1 EID1 MIS18BP1 SPATA13 INTS10 ZBTB44 IRF2 HNRNPH1 VPS13D PSIP1 EGR1 TMEM50A DUSP6 TMEM30A ZNF106 CENPC NR4A2 HIPK1 ATF2 UBA6 MAPK1 SSB CLOCK	down	***
DIDO1_TARGET_GENES	0.0000309	0.0012668	0.5573322	0.2641812	1.358713	1321	PCSK6 GPR89A RUVBL1 CEP89 DEPTOR TFAP2A NUP107 ABCA17P NEK2 COIL XYLB C17orf75 GBAP1 COA1 NUDCD3 NDC80 TSFM PRIM2 SRGAP3 THEM4 CDCA7 ECE2 ZFHX2 CDCA2 NOL12 NABP2 EIF2B5 FLAD1 TTC26 DGCR8 NUF2 ACAD9 WDR70 GOLGB1 ZNF221 THTPA KNOP1 TIGD1 UMPS DTL MCM8 MIS18A ZNF3 DZANK1 MRPS35 COQ3 AOC1 UQCC1 INTS1 FAM220A SYT12 NME1 AARS2 TOP3B WDR62 POLR3A TMEM41A KCNH2 NEURL2 EXO1 ZNF391 BBS1 BOD1 QTRT1 KIF15 PCCB AP4M1 FBXW9 FRS2 TIGD4 EXOC4 RPL32P3 AURKA EME1 NUP155 METTL7B ATR YKT6 GTPBP3 LARS2 MCM7 CENPW COASY DPCD RBM28 NSUN2 SETDB1 RAD54L MRPL3 KLHDC4 MRPL27 FANCD2 BLOC1S1 SNHG11 CCDC58 EMG1 ZNF785 TARS2 FAM162A OAZ3 POLR3C EME2 BMS1P1 MORC2 BCL2L2-PABPN1 C7orf50 PEX26 HSF2BP TRMT61B AHCY COX19 RAD51AP1 GEMIN7 EEFSEC ZNF507 COMMD4 FADS2 ALG3 MNAT1 TFCP2 SRRM5 COQ9 PPP1R37 RECQL5 PES1 RNF216 CDKN2C HPS4 DDX51 HARS2 MRPL37 LRRC6 RNPC3 CDK12 MDH1B FAM135A ZSCAN25 STX18 MCAT WDR31 BPGM DHX33 ENPP3 KLHDC9 FEN1 NUP205 TMEM79 PSMG3 TNPO2 POC1B THAP8 MTBP ATAD3A SNRPE HMGXB3 ZNF623 VPS72 CENPP WDR24 SRD5A1 DNAJC7 EFTUD2 MZT2A GOLGA3 ZSCAN9 ELMOD3 MZT2B CEP63 TELO2 INTS7 ZGPAT BBS5 ARFRP1 CCDC142 ZSCAN21 NPHP1 CCZ1B SMG5 WDR53 NDUFA11 C19orf47 NFS1 VPS41 CNOT2 DHX40 TSNAXIP1 TRMU ADNP MTOR NMRAL1 ZNF133 POLL MRPS34 CCDC151 DHODH PIGG HIRA TIGD6 SUDS3 FBXO15 TMEM237 COPS7B UBE2Q1 ZNF417 ADAR JMJD4 MLEC CCDC146 IQCK TJAP1 STX18-AS1 GUSBP1 PRMT7 GFM2 CKMT2-AS1 FAM207A C12orf73 NUP85 FAM200A CCZ1 CCDC159 AAMP CCT7 RNF187 GEMIN6 EFCAB7 SUPT16H MDGA1 LSG1 CKAP5 PSMB3 ZNF502 VPS25 PALB2 STOML2 WDR34 CHCHD1 ASB6 FAF1 LRRC59 AP3M2 CLASRP GPATCH4 FAM50B FAHD1 MRPS23 UBXN6 POLR2J BAD CHTF8 ZNF558 MRPS33 ZNF223 METTL2B WDR83 PPCDC MED24 ZSWIM8 NSUN6 UTP20 ROMO1 GNG4 NOC4L NMNAT1 HEATR1 SNRPD1 MALSU1 SNAP47 DYNC2H1 MRPL53 LTV1 SLC35A3 SCYL3 RTEL1-TNFRSF6B RAB3D GINS3 POLR2J3 URB1 STMN3 NDUFS7 KATNB1 YIPF2 SUGP1 MED27 RRP36 DDX55 ATAD2 DUS2 GTPBP10 ZNF580 FARSA NDUFV1 NME1-NME2 RER1 PRPF18 MCRS1 ZNF212 RPS26 RBM42 DBNL BBX BANF1 RTEL1 MANBAL POLR3B MRPL55 ANAPC2 DOHH STAT6 CDK5RAP1 ABCF2 TTC31 WDR4 WDR77 PRPF31 CLUAP1 HOOK2 BMS1 TTC1 TRAPPC9 TRIP4 ZNF292 BRMS1 ZWILCH SEC13 TOMM40L PFKM MARK4 GTF3C5 MRPL9 KIAA0825 RPUSD2 NME7 FAM118B TMED9 TMEM101 ERBB2 UBAP2L ZNF131 CIAPIN1 PARG MAU2 PFDN4 POP4 SMPD4 ZMAT2 NDOR1 ALG1 ZNF205 TRUB1 MCF2L2 TMEM9B-AS1 ZNF526 LEMD2 BPNT1 SLC36A1 SNRPC TBL3 PIGL FBXO45 NCAPD3 CDKAL1 NELFA MRPL20 PWP1 SART1 RAD1 MRPL48 ZER1 NDUFB7 NAT10 TRUB2 LINC00888 CALU HEMK1 BRIX1 TRPC4AP FBXL18 ZNF562 ZNF629 POGZ CSTF1 RTN4IP1 INO80B EIF2D VPS26B DHDDS MAN2C1 SPHK2 METTL4 C12orf43 MED15 RANBP10 EIF2B1 PARL CDK11B ADSL RPL36 ZC3HC1 RBL1 ZNF514 ZNF688 APBA3 CYB5RL TNPO3 NFE2L1 GGA1 OPA1 AP2B1 PANK4 VAC14 ZKSCAN4 EDC4 SNHG17 MECOM MCEE TIMM10 PGAP3 SLC4A1AP NHP2 STARD10 COQ5 RAG1 CHD8 MTMR4 CRYZ TEFM AK9 RPLP0 ALS2 CXXC1 SLC27A5 ZNF805 CACTIN EHMT1 ZNF524 SEC24C KLHL12 CCDC86 ETAA1 TIPIN RETSAT MTF2 TTC13 TXN2 FAM149B1 SLC7A6OS C1orf74 ARL1 PSMD3 ZC3H18 STRIP1 CALM3 BNIP1 KMT2D METTL17 MEN1 WDR25 SLC44A1 C15orf40 PRKAB2 NBAS POLD3 CCDC124 EBNA1BP2 COQ4 IPO4 METTL9 ZCCHC7 BECN1 PSMD8 COX6C TMEM203 MPLKIP ABCB8 C1orf43 NDUFA9 KLHL20 GPR137 ORMDL3 CLTC ACCS ZNF396 SLC39A3 TSEN15 DCTN5 C5orf51 MRPL13 RABGGTA EDC3 GATM KCTD16 RAD51B RFC3 NVL GLB1L MRPL33 ZNF335 JRK RFC4 IFT74 REXO4 SUCLG1 COX16 ATXN2L CHFR VTI1A ZNF546 POLR2J4 USP31 RRP1B HSD11B1L C1orf35 ZBTB17 ZNF200 ITGB3BP TUBGCP6 DDX31 WDR92 MAPKAPK5 TIMM23 TSKU PHAX PRKCSH VMAC DRG2 DNAJC16 UBE3B TARDBP POLR2C SLC35B1 LZTFL1	up	**
AEBP2_TARGET_GENES	0.0001697	0.0046899	0.5188481	0.2660308	1.357600	981	PRR15 CEACAM1 FAM227A PPP1R1B HJURP RUVBL1 CEP89 TICRR GMDS GPT2 ZNF273 C1QTNF6 ZMYND8 CHEK2 ZNF12 CCNB1 CENPF IGF2BP3 DROSHA C17orf75 HOXB6 C21orf58 SEMA4B GGCT TTF2 CHCHD6 PHF14 PIF1 RGMB-AS1 MRPL46 CDCA2 AGFG2 ANKZF1 FLAD1 SAP30L-AS1 DGCR8 IFT27 CENPA ACOT8 TPX2 MCM4 STRIP2 LSR TYMS EIF3B PLS1 TDRKH SGK2 LIPE-AS1 CAND1 RCCD1 FSTL4 AVL9 ZWINT LRRC31 GOLPH3L CEP250 TJP3 WDR62 POLR3A BZW2 RAB11B-AS1 STAP2 MRPL15 AP4M1 WASF1 PAFAH1B3 MAP3K13 TPBG BRAT1 CCDC77 TOP2A EXOC4 CCT5 IQCD HHAT SMARCAL1 MCM7 TPCN1 LIPE PRKDC RHOBTB3 TMEM45A HOXC6 AMACR MCM3 CDC25C PFN2 ZNF785 TARS2 CHD6 SARS2 ORC6 ACTL6A CBY1 ABCB9 DNAAF3 SPC24 MRPS11 SPATA17 LRRC61 BRIP1 DDR1 OGFOD2 SLC35E2B ARL16 C4orf47 SRRM5 TULP3 CKS1B MRPL36 NRSN2 FRMD5 ASF1B ANAPC5 CDK1 PABPN1 WDR5B SSBP1 CCDC61 RFWD3 PLA2G2A PICK1 RBCK1 POC5 ACP6 UNG VPS28 ZNF815P DGAT2 AP5Z1 PMEL RNF181 ACTR3C ZNF789 ANAPC7 SPAG5 LINC00649 THAP8 TTC16 NOP2 VPS72 CENPP ZKSCAN5 DNAJC7 IFT52 KPNB1 HYKK GIPC1 DNMT1 ZNF687 CEP63 CDC23 AKR1E2 PDCD11 SATB2 DCAKD SPG7 VPS41 SLC26A2 GALK2 MTOR DNAJA3 PUS1 TRIM9 FHIT UROS DOK4 MORN2 COPS7B DPH2 TK1 RHBDD3 AKAP8L HDAC1 MLEC OS9 ANP32E DAP3 LIN37 ZSWIM3 ASNS TM9SF4 DNMBP AAMP NAIF1 CCT7 NR6A1 RMND5B KDM3A CENPK TADA3 ACBD5 LSG1 LIMA1 CKAP5 PWWP2A CDC20 DGKA ORMDL2 RPRD1B CENPM CA11 SIRT4 GBF1 AP3M2 BCL2L1 NOL6 ABCA7 KRT8 ARVCF HOXA3 KDM4B EML6 RPL7L1 MED24 PRMT1 RPPH1 ANKRA2 UIMC1 MALSU1 C5orf22 FAM161A LANCL2 PYGO2 SRSF1 AATF KATNB1 DOLPP1 DUS4L POLR2I CREB3L2 RGMB LSM4 STK35 MVP CEP152 COPZ1 SPSB3 MICAL3 COG5 CYTH2 NCDN RBM42 ULK4 PRR11 BBX FKBP9 VDAC1 TXNL4B DOHH ZNF436 CEP164 NUBP2 PPFIA3 GTF3C5 SNX8 TBCB ALKBH6 BCAS3 POLR1B BCL6 TMEM260 CENPE POLR1A ANKMY2 PFDN4 FRMD6 NMT1 HGS TIMM44 FIS1 ZNF526 ZNF354B MRPS27 SIGMAR1 PPIA UBE2C PNN TTC9C PTOV1 SFXN5 DCAF11 ZSCAN20 TMEM38A MRPL48 COX6B1 STK11IP TTLL5 SCAF1 SART3 TMEM161A ATP6V1E2 MSANTD4 ANKRD11 CYB5B ZNF629 PHRF1 PARP2 COPE SUMF2 TMEM62 RPL23A DHX57 MORN4 PDXP MBTD1 ZNF678 PPP1R13L SPHK2 PDK2 SH3RF2 UTP18 TRAFD1 AKAP9 PCNT ZC3HC1 SRI TBC1D10B FBXO5 ABHD2 NFE2L1 MEGF11 TMPO ZNF774 MCEE ZNF414 TRAF7 NHP2 GLRX5 ZNF77 COQ5 RAG1 MPZL1 MTMR4	up	**
MIR548BC	0.0010009	0.0163729	0.4550599	-0.2329051	-1.351930	415	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 PIKFYVE RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 PIAS2 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	*
MIR545_5P	0.0024692	0.0307092	0.4317077	-0.2412163	-1.351881	266	RAB11FIP1 SC5D SLC12A6 GAPT BDNF BACH1 QKI ZCCHC2 VAMP2 ARL8B ATF7IP2 ASAP1 LATS2 ENTPD1 RAP1A SDE2 SLAIN2 FOXJ3 CD58 PTPN21 AHNAK TSPAN12 PKD1L1 YBX3 RNFT1 ROCK1 ERP44 CCND2 CCSER2 ELK3 TBX5 PRICKLE2 BCLAF1 KPNA3 AKIRIN1 PDK4 UFM1 MYLIP RYBP RAB8B PPA2 GABPA APBB2 DUSP8 RCAN1 DDX5 PCGF5 IDS MORC3 AP3B1 CELF2 MAPK8 PHF3 PDS5B TSC22D1 CSDE1 TOB1 HINT3 GATA6 NBEAL1 PLEKHO2 MBNL1 ATAD2B BNIP3L B3GALNT1 UBE2D1 SSH2 C7orf31 LYST MMD PAIP2 SAMSN1 DOCK4 NAA15 SFPQ CNOT8 BMI1 ACVR1C CFL2 MAPK1 MAMDC2 ANKS1A ATP1B1 VPS36 SGIP1 CAPZA1 SGPP1 STX16 ARHGEF12 PAXBP1 DR1 MAP3K1 RNF111 WDR26 SETD2 KATNAL1	down	*
ZNF274_TARGET_GENES	0.0009489	0.0157349	0.4772708	0.2669231	1.351759	767	SAA2 HNF1A TP63 BBOX1 DDX11 ENTPD2 BDH1 PMFBP1 TFAP2A IGLV1-36 DROSHA FAM177B DDX11-AS1 GBAP1 JPH3 SEMA4B PHF14 RAB3IP LCN2 ASIC1 IQGAP3 SPAG17 ANLN STK31 ASPM PCLO STIL ANKRD24 NUF2 IGLC7 GPI TBX19 ESPL1 E2F3 ANKRD22 PRC1 C19orf57 GON4L MAP2K6 ZFYVE19 KIAA0895 LRRC27 SLC4A8 CYP3A5 SCG5 FAM220A LDHB ZSCAN2 BZW2 ZNF607 NUDT1 MUC6 DLG1 SMARCC1 GFPT1 LINC00665 FANCA CCDC77 CCT5 MYO10 CARD10 TPR RHOBTB3 TRRAP ADAMTS13 PKM WDR73 RIMKLBP2 XXYLT1 LETMD1 BRD9 RAB13 EHHADH ABCB9 MDM2 ZNF48 BRIP1 RABEP2 BLM C2CD3 ALG3 MIPOL1 MYOT FRMD5 CROCC EFCAB6 POLE2 UCK2 PACS1 KIAA0753 RAPGEFL1 ANKRD54 RN7SL812P GIPR PGBD2 PSMB5 MRPL17 KIF2A ANAPC7 NUP205 TRAPPC12 HMGXB3 DIAPH3 ANKRD55 CPXM1 ANXA2R LZTR1 UBN2 ZNF692 NET1 MYO19 ACBD6 ZNF354A FANCG CAPS2 CRLF1 CCNE1 DNAJC17 DLGAP5 SMG5 VPS41 ADNP MLF2 AARSD1 MAN1B1 POLL ADAM28 XYLT2 TRIO OSBPL3 PTGES2 IQCG TRIM37 DUSP12 ENAH CASP7 CENPQ CCDC146 HECTD1 FZR1 MTND5P11 RNF224 YWHAQP6 FHL2 IQCH LIPC SLC1A3 NAIF1 CCT7 RAD50 CENPK PPIEL DGKA PLD1 YLPM1 LINC00467 TTLL3 FBXO22 TCTN1 AP3M2 FAHD1 FIBCD1 PHYKPL CHTF8 C4BPAP1 STAMBP FAM174A RPL7L1 ZNF432 UIMC1 DDX23 LTV1 RTEL1-TNFRSF6B SRSF1 EFHB SDHCP2 RGMB PI4KA ANK3 CHRNA5 ZNF274 MST1P2 C1QTNF3 STRBP DPH5 FARSA ZNF286A DBNL GRHL1 MSS51 GTF3C2 PLSCR2 DTNB SERPIND1 ARRDC1 ARHGAP5 FBN2 MICU1 IKZF4 GNA14 AGBL5 NUBPL ENPP5 GNA12 POLR1B MIR181B2 OFD1P17 TP53 NEIL1 TMEM9B-AS1 FBXO34 ZNF354B SLC38A4 IDUA COPZ2 TTC9C NCAPD3 CLDN10 PPP2R5D RN7SL334P MRPL48 ATF7IP DDB2 NAT10 TTLL5 IMMP2L CYP11A1 KCTD19 SETD5 ANKRD11 ANKRD13D TPM1 MEIS3 TMEM62 INO80B EIF2D VPS26B PLAC8 RPS20P15 VPS18 ARMC2	up	*
MIR520D_3P	0.0021909	0.0286814	0.4317077	-0.2410060	-1.351181	287	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 PLAG1 ARHGEF17 CFL2	down	*
MIR613	0.0025975	0.0317750	0.4317077	-0.2408252	-1.349724	278	TSPAN4 SOWAHC TBX3 TTC7B BDNF MMRN1 CORO1C CITED2 SLC25A30 NEDD9 CBL NFATC3 ZEB2 SEMA6D TRA2B PICALM FOXP1 HIPK3 EIF4E ASH2L PLXNA4 ANKRD29 HNRNPU FLI1 SLC7A2 CPED1 HMGN1 KLF4 THBS1 ZNF24 MGAT4A PIK3C2A WDR48 PEAK1 NCOA1 C2orf69 NINJ1 ELF1 PDIK1L CREM UTRN LRCH1 HMBOX1 ETS1 SNX2 DDX5 PRKCE CAP1 SLC10A7 YWHAZ CEBPZ TAGLN2 CDK14 FOSB AZIN1 AP1G1 KCTD10 VAMP4 ATP6V1A NAB1 MYOCD ADPGK HACE1 RNF138 CTTNBP2NL WDR1 RAB5A METTL21A ACTB MEX3C TIMP3 EDN1 RNF38 MMD SAMSN1	down	*
MIR513A_5P	0.0023793	0.0300927	0.4317077	-0.2354083	-1.347964	316	SEMA6A ABHD5 PRKG2 SNX10 DPYSL2 ZBTB34 TMEM170B CD44 ST3GAL6 KIAA1109 GTF2I HMGCR DYRK1A RGPD5 OTUD4 ADAM17 LATS2 MTF1 BTG2 FZD4 KLF6 SLC7A11 ABHD6 ASH2L GATA3 SFRP1 RAB14 NODAL SLC7A2 TLE4 CCDC82 PPP6R3 LIN7C ZCCHC24 PDE8A MGAT4A NPAS3 ARHGEF26 PTGER3 CCSER2 RNF139 FAM76B SNN BTG1 SLC25A25 ID4 FAM189A1 DNAJC27 EBF2 MAGI2 NECAP1 C2CD2 RCAN1 DDX5 GRB2 RC3H1 MORC3 SNRK CDK14 AGFG1 GRSF1 AGPS NIPAL4 YTHDF3 SLC35F1 PKIA AKIRIN2 STRN PHF3 PDS5B SBF2 APLP2 ANKRD12 NPTN KAT2B ATAD2B INO80D PET117 UBE2D1 VSIG10 RASSF8 MARC1 TLK2 PRKG1 MMD SAMSN1 NABP1 SMAD4 HSDL1 SPATA13 UBE2V1 ACVR1C TSTD3 TREML1 ZNF800 ADAMTSL1 LIN52	down	*
HNF1A_TARGET_GENES	0.0000159	0.0007319	0.5756103	0.2613780	1.346857	1445	MNX1 TSPAN8 ATP6V0A4 DKK1 PKHD1 KIF12 SYT8 PRLR TF CDHR2 HNF1A HKDC1 B3GALT5 BBOX1 NPC1L1 HABP2 ABCC2 SLCO5A1 FGA C1GALT1 HOXB-AS3 FOXA3 CDH17 KRT5 LAD1 RUVBL1 DNAH2 BDH1 BHMT SLC13A3 DEPTOR CHEK2 SPINK13 CP NUP107 SLFN13 ANKFN1 NEK2 BAIAP2L2 UGT8 SOX2 FRK APOLD1 C17orf75 ACMSD GCNT3 LINC00941 RAB3IP TSFM TTC39A TBRG4 TMEM86B CDCA7 GAL3ST1 SIX4 IRS1 TUBB2B LCN2 XKR4 GINS1 CDCA2 BCL2L15 SLC27A2 CATSPERB ABCA12 STK31 PMS2CL NAALADL2 IGLV3-9 SPP1 TTC26 NUF2 KCNQ5 PROC MST1L ALDH18A1 ECT2 CUEDC1 RBBP8 ARHGAP33 TYMS SP5 SLC4A4 DNAH3 FERMT1 GRB7 EFNA5 SLC7A9 PAH ACY1 TMCC1 HNF4G MAP2K6 ZFYVE19 SGK2 LIME1 VILL DZANK1 COX11 LRRC31 SPDL1 GPX2 SCG5 NME1 SIPA1L3 TOP3B RANBP1 MANSC1 POLR3A CCDC150 C1orf220 NEURL2 BTRC ZNF572 CUL9 ALG1L BICD1 MRPL15 TRIM29 KIF3B BUB1 IDO1 BPHL APOL1 AGT THBS4 C1orf226 KLHDC7A SFI1 HAVCR1 ZNF174 RSRC1 COASY MPHOSPH9 CPD C1RL RRM2 ANKRD52 WDHD1 RNF43 IL20RB ANKDD1B ZNHIT6 DCDC2 MCM3 WDR66 LINC00511 WDR72 CCDC58 TARS2 ANG MDK CHD6 PSMG4 ZNF443 RIPK4 ZNHIT1 PDZK1IP1 ARHGEF38 TRMT61B PSMD4 THAP10 KHK TBC1D8 TRMT2A MRPS11 DNAH11 C22orf46 FDXR GRHL2 COMMD4 SYMPK NAA40 C2CD3 IDH2 ALDOA MNAT1 STXBP4 SPRY1 PARD3 SLC39A5 ENTPD5 PPP1R37 DHRS13 PES1 GCKR MIPOL1 FGGY CKS1B EXOC3L4 RASSF6 ISOC2 NSF FRMPD2 PLOD2 ANAPC5 OSMR CDK12 LRP2 SSBP1 STON2 DIDO1 ZNF652 CCT3 EEPD1 GMNN DMGDH TBX15 STX18 MKRN1 DGAT2 WDR31 SLC25A13 PMEL DHX33 ENPP3 FAM186A KRBA1 ZNF775 TMEM79 MECR POC1B LINC00649 SEMA3A SNRPE HMGXB3 CCDC57 PBLD ZNF827 FAM102A WDR24 CPXM1 ZNF500 IFT52 UNC45A EIF6 LGR5 GOLGA3 ACBD6 RPS18P9 ELMOD3 G6PC3 PLEKHM1 DNAJC17 EDEM3 VWA5B2 SMG5 SPG7 COA3 VPS41 GALK2 ADAM28 UROS LLGL2 S100A16 DHODH PLEKHG3 PIGG GPRC5C SLC37A4 ASGR2 IQCG RGS22 CCDC130 ENAH ZNF761 MLEC MSI2 CSNK1G1 GAS2 SLC22A5 CCDC146 MAPK10 USP43 STX18-AS1 LAMTOR2 MMP7 DNAJC11 ZNF768 SLC4A2 DNMBP SEMA4G ACSL6 C12orf73 TAS2R19 LIPC PRRG2 OLFML2B ATAD5 ENC1 AAMP CNDP2 IP6K2 DHTKD1 ETV4 BAZ2A SASS6 KLC4 SH2B1 TADA3 UBQLN4 EFCAB7 LSG1 CKAP5 CPSF4 COG1 VPS25 RPRD1B CENPM PLD1 AHCYL1 FTCD SIRT4 MAN2A1 LIPG MRPS23 ZNF76 PPP6R1 ABCC3 IGFL2 KRT8 GID8 RAI14 CENPT NSUN6 DHX8 NOSIP HIBADH	up	***
MIR548A_3P	0.0006716	0.0128344	0.4772708	-0.2319560	-1.346389	413	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP TMED5 MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	*
MIR202_3P	0.0042069	0.0437208	0.4070179	-0.2481448	-1.345877	211	TRIM71 SLC31A2 MS4A7 DLC1 TRHDE CPEB2 ADCY9 GPCPD1 GTF2I C8orf58 GNPTAB TET2 TRIB1 SPCS3 ASAP1 BTG2 SPIRE1 RB1 ADRB2 CPED1 EVI2B IL10 AGO4 ROCK2 PTPRO LEPROTL1 ROCK1 MYRIP USP44 LBH CCND2 DUSP1 RNF139 ADIPOR2 ADAMTS8 CNOT6L FOXN3 MOB4 SCEL FAM189A1 RAB8B UTRN LIMD1 CPEB4 GABPA IPO7 SKIL ATL2 CAP1 YPEL2 CD164 NIPAL4 EPHA3 ABHD13 SH3RF3 CCDC68 COL15A1	down	*
MIR579_3P	0.0008822	0.0151786	0.4772708	-0.2325099	-1.344962	411	GCOM1 MBOAT2 ZBTB34 MMRN1 MED4 CLEC12B LONRF1 NEDD4L QKI NTM KCNN3 DSCAML1 MOB1B TMX4 DNAJB14 ZBTB4 WWC2 NCEH1 B3GNT5 UBL3 SLC25A17 ARSB RAP1A SWT1 BZW1 SERINC1 SPIRE1 GLS CAV2 CAMTA1 SLC7A11 GLDN TBC1D9 ARRB1 DGKE SORBS1 LIMS1 KLF9 ANKRD10 KLF7 MYRIP SEC24B ERP44 LAPTM5 NPAS3 AQP4 PTGER3 CPT1A PTCHD4 GNAQ PRICKLE2 NUS1 TBC1D4 FAM76B NCKAP5 IKZF5 CLIC5 GPBP1 PDIK1L LRRTM2 PHACTR2 NEK7 PLEKHA3 OXNAD1 GABPA APBB2 IPO7 SKIL PNPLA8 PIK3R1 IRF8 FRYL COBLL1 HSD17B12 SH2D4B ZNRF3 UVRAG OGFRL1 DENND4A CDK14 AGFG1 RHOQ AGPS CALM1 YTHDF3 USP7 PSMD12 HSF5	down	*
TGCTTTG_MIR330	0.0033708	0.0376540	0.4317077	-0.2417270	-1.343708	255	SOSTDC1 BACH1 QKI BMPR2 DYRK1A TGFBR3 OTUD4 NFATC3 ZBTB4 ATP2B1 NCEH1 TRA2B RAP1A PLXNA2 PICALM LUZP1 ZNF410 EIF4E LHX6 HNRNPU GPM6A TIPARP ZCCHC24 ZNF423 TJP1 ITPK1 ID2 SMAD7 PAFAH1B1 FOXN3 RAB6A MTPN BTG1 ETF1 SLC25A3 SNAP23 APPL1 JPH1 MTMR9 APBB2 FYTTD1 SKIL MBNL2 RC3H1 TRAK2 NAA30 YPEL2 HIVEP2 RUNX3 STXBP3 TFEB SLC8A3 KAT2B PHLPP2 MBNL1 PRDM8 BMP2K PDLIM5 RLF CEP170 TRAPPC8 BRWD1 CREBBP FNBP4 SIN3A FOXJ2 PRKG1 PAIP2 KIF1B FGFR1 ITCH CCND3 RHOT1 WDFY3 MACROD2 BMI1 MIER3 ZBTB44 CHP1 ZNF800 HIPK1 MAPK1 MYH10 CMPK1 EFNB2 CSNK1G3 CTDSPL2 API5 CAPZA1 PCMT1 TYRP1 KLHL9 RNF111 FCHSD2 NR4A3 TRIM3 GTF2H1 YOD1	down	*
GGGTGGRR_PAX4_03	0.0000058	0.0003989	0.6105269	-0.2127462	-1.343197	1010	SMAD6 HSPA12B SEMA3G GPR17 SEMA6A MGAT3 SOSTDC1 SLC12A6 TSPAN4 DENND5A TAL1 TRHDE RASIP1 USP12 KLF13 CD55 HHEX TBX3 RBMS2 PHYHIP TIE1 DPYSL2 MIR22HG KCTD9 LINC00472 TRPV2 ARHGEF15 FOLR1 FYN SH2D3C RADIL RASAL2 NEDD4L RTN3 FLVCR2 BMPR2 ESAM DYRK1A KBTBD3 KCNN3 FBXO3 NR3C1 MSLN ANAPC15 AGPAT4 SCARF1 PFDN1 PPM1D HSPG2 RHOA SH2D6 NFIX MAN2B1 SEMA3B HBEGF ADA FOXA2 ENTPD1 EIF1 MTF1 C1orf21 GNGT2 ITGA5 PRELP ZNF503 PICALM RNF125 FZD4 KLF10 MS4A1 EIF4E NR4A1 SRSF2 SLC25A37 TNS1 CRK SFRP1 SPRY2 WNT3A ZEB1 ARHGEF2 UBE2D3 HPSE2 BAG1 MTHFR CD37 FLI1 UNC45B PTPN12 KIF1C TIMM10B TNNC1 AHNAK PIP5K1B TRIM46 YBX3 RNFT1 ST3GAL2 SLC12A4 ID3 ROCK1 ZFAND5 USP2 ZADH2 ADAMTS9 KLF7 SPAG9 FMNL3 C1QTNF7 CDKN1A CADM1 SIK2 TMSB4XP8 KCNMB1 GPR85 VIM AQP4 AXL GSDMA CCND2 FRMD4A UBE2B ELK3 CPT1A TBX5 FXYD7 PPP2R5A CYP26B1 PAFAH1B1 GNAI2 DCHS1 MAFF CRTAC1 CRIM1 ADD1 RSRC2 KREMEN1 ARHGDIB PIAS1 FOXN3 RAB6A PROCR SRF ZCWPW1 MCMBP MYO1C WNT9A S1PR4 CNTF FLT1 IL6 WASF2 BCAR3 TRIM55 SLCO2B1 PODN LAMB2 JUN HMBOX1 RHOBTB2 ZFP91 KCTD12 HIC1 MN1 DDX17 EPC1 DUSP8 FERMT2 DHX15 SKIL FBXL16 LYRM1 PCGF5 PRKCE LGI4 HOMER1 EGLN2 YWHAZ RASSF2 RALB DEDD ZBED5 GRIK1 FGFR4 MORF4L1 SLC25A24 SPRY4 ADNP2 KRTCAP2 BCL6B CDK17 YTHDF3 RUNX3 SRSF6 PRKCG PKIA FLNC SPOP AZIN1 ZNF521 AKIRIN2 HNRNPA2B1 TCF4 AP1G1 SBF2 YTHDF2 SKIDA1 DUSP5 ZBTB11 ATP6V1A CBFA2T3 PIM1 ATP6V0C ATXN1 HBP1 GNB4 TOB1 KYNU STX12 GATA6 ZNF296 CLCN6 ABI3BP MBNL1 DBNDD2 SMAD2 INO80D HAUS3 SLC43A2 SESN1 LAT ARPC2 ZNF143 ELP2 CALHM2 DCTN4 OSR1 RTN4 CDC42EP3 TAB2 TOB2 CCR9 PTCH1 HNRNPK RBMS3 SREBF2 HNRNPC RAPGEF3 ABI3 ADORA2A JMJD1C RNF38 FOXJ2 MTUS1 THRAP3 SYNPO2L FGFR1 RORA COL13A1 NRG1 FAM13B NAA15 ZFPM2 IQGAP1 GSPT1 TLK1	down	***
PRKDC_TARGET_GENES	0.0008761	0.0151786	0.4772708	0.2666306	1.342654	694	PRR15 SLC2A1-AS1 RUVBL1 CEP89 C1QTNF6 DOC2A DROSHA GBAP1 SEMA4B SLC2A1 PHF14 RGMB-AS1 BRCA1 CREB3L4 CDCA2 ANKZF1 FLAD1 IFT27 CENPA ACOT8 CCNB2 VSTM2L ZNF714 TIGD1 CDC25A PRC1 TDRKH LIPE-AS1 CAND1 SRPK1 KRT15 TRIM45 ZNF726 GOLPH3L RUVBL2 POLR3A CLSTN3 RAB11B-AS1 OSBPL2 CHAF1A SLFN5 HLTF EMC9 LINC00665 TP53BP1 TOP2A IQCD NDUFS2 ZNF587B KLHL25 ZNF174 C14orf93 TPCN1 GNAS-AS1 TMEM45A BRPF3 PASK MCM3 TARS2 CHD6 ZNF443 C7orf50 ORC6 ACTL6A AHCY ANKRD16 SPC24 CNOT3 ZNF587 ERCC2 INCENP EFCAB11 HPS4 FRMD5 CBX5 MRPL37 ANAPC5 PABPN1 CCDC61 RFWD3 CCT3 ANKRD54 ERC2 POLR3K UNG PMEL BPGM C16orf71 KXD1 RALGPS1 PLCG1 DIAPH3 STK11 CHCHD2 SNRNP25 VBP1 ZNF687 UBFD1 CDC23 DLGAP5 DCAKD SPG7 SLC26A2 MTOR TRIM9 FHIT OSBPL3 SLC37A4 HIRA COL5A2 ROGDI COPS7B ZNF417 PLEKHA8 NFATC4 AKAP8L LMTK2 OS9 ANP32E ITFG2 LIN37 ZSWIM3 ZSWIM1 FKBP14 ZNF814 AAMP NAIF1 ZBTB7B CCT7 NR6A1 CCDC137 SEC14L2 GTF3C1 PWWP2A PSMB3 ORMDL2 GBF1 C12orf65 NRXN2 AP3M2 BCL2L1 CDR2 ABCA7 ARVCF KDM4B MRPL28 PRMT1 HIBADH ANKS3 TDP1 ZRANB3 C5orf22 FAM161A ZNF563 LRCH4 ZSCAN32 EXOSC5 CREB3L2 RGMB CCNG1 RSPH4A TCERG1 COPZ1 SPSB3 ZNF837 ZNF519 PMS1 ATP6AP1 TRAPPC12-AS1 CYTH2 PRR11 BBX ZNF66 DOHH ZNF436 NUBP2 ARL17B NBR1 TOMM40L MROH1 BCAS3 ZNF91 TCF3 DNAJC14 EARS2 RHPN1 PGPEP1 MTHFD1 PDZD7 DHRS3 NMT1 TIMM44 PPIA UBE2C RHPN1-AS1 SFXN5 DCAF11 ENO1 ZSCAN20 SLC39A1 PLIN3 COX6B1 THAP3 TTLL5 FAM222B TMEM161A MSANTD4 SETD5 ANKRD11 RPUSD3 COPE DNAL4 HEXIM2 POLRMT PDXP SETD1A ZDHHC13 ZNF678 PPP1R13L WDR63 HRAS RAB40C TRAFD1 TBC1D10B PPP2R5E TRPS1 LCMT1 APBA3 CYB5RL ABHD2 CCDC153 FAM111B NFE2L1 SAFB TMEM9 SLC2A8 ZNF774 TRAF7 GLRX5 ZNF77 CHD8 MPZL1 ZNF682 ARMC6 RPLP0 ABCD3 SHKBP1 AP2A1 RMI1 HNRNPAB PC LRPPRC FMN1 MTHFD2 DHX38 SWSAP1 EVI5L ELMO2 BBS12 DDX49 SCAND2P ZNF691 GLCE TLE1 LINC00654 SNHG10 TANGO2 HNRNPA1 SKA2 ABCB8 WBP1 KHSRP BUB3 GYS1 SLC39A3 CIC TSPAN15 STPG1 NPHP4 GATM ZC2HC1C HNRNPUL1 DAPK3 PET100 BCKDHA ARL17A ENSA ZNF823 KANSL1 ZNF200 YIF1A ZBTB38 PACSIN2 FUT8 TUBGCP6 TMTC4 ZNF431 ANKRD27	up	*
ZC3H11A_TARGET_GENES	0.0008828	0.0151786	0.4772708	0.2653620	1.342359	753	MIR1205 FBXW8 ZDHHC4 ZMYND8 PDCD6 NUP107 ABCA17P C17orf75 NPAS1 DDIT4 THEM4 C6orf141 ASIC1 LRRC37A3 UBE2Z NOL12 ILDR1 TTC26 DGCR8 NUF2 AURKB TIGD1 XRCC2 CDK5RAP3 PVT1 AGK INTS1 LSM5 NME1 TOP3B CASP2 TMEM41A ZNF74 NLE1 XPNPEP3 ZNF391 BBS1 KIF15 KNTC1 IGF2BP2 RFXANK ITGB4 SAE1 GTPBP3 E2F2 LPIN3 RBM28 CCDC58 TARS2 YEATS2 SLC37A3 EME2 HEBP2 ZNF786 TRMT61B GAS8 TMEM63A B4GALT7 GEMIN7 DDR1 EEFSEC SPAG8 ALDOA PPP1R37 DHRS13 PARP1 GEMIN4 RNF216 C9orf163 PPIL2 DDX51 MB SUPT5H CBX5 ASF1B PAK1 ANAPC5 SSBP1 EXOSC2 STX18 VPS28 MCAT WDR31 FAM98C DHX33 ENPP3 PSMG3 TNRC18 HMGXB3 CCDC57 CENPP WDR24 KPNB1 GOLGA3 ZSCAN9 EXOC7 DTX2 NADK2 GALK2 TRMU ADNP JOSD2 TRADD MRPS34 CCDC151 KIF22 PIGG SLC37A4 HIRA USB1 TIGD6 COPS7B ARL6IP4 JMJD4 MLEC GEMIN5 STX18-AS1 LRWD1 ZNF768 IGLV1-47 GFM2 TSEN54 KDM3B FAM207A C12orf73 GNAZ PRRG2 ZBTB45 CLTB DNAJB13 DHTKD1 ETV4 RNF187 FAM71E1 SH2B1 EP400 EFCAB7 PFAS CPSF4 VPS25 STOML2 KIAA0100 CA11 HMGA1 DUS1L FBXO22 BEND6 SLFN12 ALKBH4 ZNF76 PPP6R1 NOL6 MADCAM1 SRRT MRPL24 DHX8 NOSIP MCM5 TMEM147 NOC4L SNRPD1 SIRT5 SNAP47 SLC35A3 CACNB3 RTEL1-TNFRSF6B NFE2 STMN3 NDUFS7 YIPF2 WDR45B IGHMBP2 PI4KA DDX55 MST1P2 DUS2 ZNF580 NME1-NME2 PRPF18 AGMAT TSPAN10 CYTH2 BANF1 RTEL1 POLR3B MRPL55 CLUAP1 ACSF3 CCDC88B LPGAT1 BMS1 TTC1 TRIP4 SEC13 CHMP1A PFKM MARK4 GTF3C5 MRPL21 SNRNP200 VPS9D1 CHMP2A TMEM101 AURKAIP1 MAPK8IP3 ADRM1 ZNF205 GGCX ZNF341 FBXO34 PPIA TBL3 PIGL DCDC1 UBTF MRPL20 TMEM98 SART1 SPATA20 ATF7IP ZER1 CLASP1 TRUB2 HEMK1 TRPC4AP SNAP25 SLC33A1 SPATA33 KIAA0586 INO80B ZNF554 EIF2D SHROOM1 ABLIM3 MAN2C1 MED15 RAB40C NELFB AKAP9 COMTD1 TMEM259 RPL36 NOXA1 ZC3HC1 ZNF276 SDHAF1 TNPO3 OPA1 PANK4 SAFB LTK NSL1 EDC4 MCEE TYK2 TEFM GAK SAFB2 SLC20A2 NUDT8 SLC27A5 MAP3K5 MBD6 DGCR2 RBM8A GGA3 KEAP1 TXN2 OLFM2	up	*
MIR106A_5P	0.0003882	0.0086738	0.4984931	-0.2233516	-1.340976	554	WEE1 RAB11FIP1 EREG TMEM100 ABHD5 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK SGTB BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 MAPK8 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 TGFB1I1 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	**
MIR548H_3P_MIR548Z	0.0003414	0.0078616	0.4984931	-0.2253060	-1.339686	518	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 CPEB4 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA	down	**
MIR3065_5P	0.0011786	0.0183222	0.4550599	-0.2298251	-1.339667	381	NOVA2 OSBPL11 SECISBP2L CD55 CAT RAPGEF2 KCTD9 PLEKHF2 ELF2 SRSF7 S1PR1 CDC42 OTUD4 DNAJB14 RBM7 UBL3 NDUFAF7 KLF10 FOXP1 GLS SLC7A11 DACH1 ZMYM6 ZEB1 ARHGEF2 SOX7 PDE4D PDGFA GPM6A EIF1B KIF1C ROCK2 TLE4 ACSL3 REST UBE2E2 HNRNPUL2 AQP4 HOPX WASF3 ARL4A SLC25A32 PAFAH1B1 SPRYD7 SMNDC1 CRIM1 CPLX1 EFR3A ZDHHC20 UFM1 GPBP1 ARL6IP5 DCP1A VPS37A PKNOX1 MED28 PHACTR2 HECA WSCD2 ETS1 ADRA1A BMP3 CCDC50 ATXN1L PIK3R1 ATL2 FSD1L SLC10A7 NUDT15 TMEM192 EPPK1 ING3 CHORDC1 AZIN1 TCF4 DCAF5 ZBTB1 DCK PDS5B ZBTB11 ATP6V1A MAP3K2 CNTNAP1 MEIS1 SMAD2 EPB41L5 LRP12 UBE2D1 KPNA4 RBMS3 MAP3K4 NPAT JMJD1C SCAI DNAJB9 SAMSN1 RORA NRP2 DOCK4 ENY2 SPATA13 SCLT1 CDKN1B ZNF800 LNPEP SSB CLOCK PLEKHA2 CCNT2 SRSF11 PRTG UBE2W SGIP1 SCAF11 HMGB1 CRIPT PYROXD1 ATP2B4 NFIL3 B3GALNT2	down	*
MIR372_3P	0.0042417	0.0438392	0.4070179	-0.2373477	-1.337908	288	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 PLAG1 ARHGEF17 CFL2	down	*
MIR548E_3P	0.0013116	0.0200070	0.4550599	-0.2297716	-1.335191	414	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 PIKFYVE RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	*
MIR17_5P	0.0002686	0.0067716	0.4984931	-0.2207958	-1.334186	539	WEE1 RAB11FIP1 EREG TMEM100 ABHD5 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK SGTB BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 MAPK8 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 TGFB1I1 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	**
MIR664B_3P	0.0012297	0.0189593	0.4550599	-0.2296129	-1.334125	404	GCOM1 MBOAT2 ZBTB34 MMRN1 MED4 CLEC12B LONRF1 NEDD4L QKI NTM KCNN3 DSCAML1 MOB1B TMX4 DNAJB14 ZBTB4 WWC2 NCEH1 B3GNT5 UBL3 SLC25A17 ARSB RAP1A SWT1 BZW1 SERINC1 SPIRE1 GLS CAV2 CAMTA1 SLC7A11 GLDN TBC1D9 ARRB1 DGKE SORBS1 LIMS1 KLF9 ANKRD10 KLF7 MYRIP SEC24B ERP44 LAPTM5 NPAS3 AQP4 PTGER3 CPT1A PTCHD4 GNAQ PRICKLE2 NUS1 TBC1D4 FAM76B NCKAP5 IKZF5 CLIC5 GPBP1 PDIK1L LRRTM2 PHACTR2 PLEKHA3 OXNAD1 GABPA APBB2 IPO7 SKIL PNPLA8 PIK3R1 IRF8 FRYL COBLL1 HSD17B12 SH2D4B ZNRF3 UVRAG OGFRL1 DENND4A AGFG1 RHOQ CALM1 YTHDF3 USP7 PSMD12 HSF5	down	*
MIR548AR_3P	0.0006332	0.0122416	0.4772708	-0.2229859	-1.333746	489	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 SIK1 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 BZW1 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 TAPT1 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 ZFAND5 VASP TMED5 KLF7 MYO1B GPR85 HNRNPUL2 UXS1 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 BCLAF1 SMNDC1 CNOT6L PIAS1 SERTAD2 FLT1 VPS37A DNAJC27 PKNOX1 MED28 EBF2 NEK7 PIKFYVE HCFC2 DHH RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 TMEM167B SLC25A24 CTTNBP2 CALM1 FOXO3 MSMO1 SLC4A5 NAA16 CHRAC1 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 GSPT1 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A FJX1 DKK3 ZNF106 ATF2 CDC42BPB ADAMTSL3 PIK3CG XRN2 SV2B TRPM7 PIAS2 SGIP1 IER3IP1 GPR137B VSTM4 WDR47 PDE7B GABPB1	down	*
CBX5_TARGET_GENES	0.0026812	0.0324791	0.4317077	0.2659843	1.332193	601	PDE11A PCSK6 HNF1A MYEOV MROH3P C1GALT1 KRT5 LAD1 BDH1 GPT2 PMFBP1 EPN3 SLC13A3 NGEF SYNPR PRSS2 ZNF280B COA1 PRIM2 ZNF138 FABP6 LRRC37A3 FA2H NPAS2 POLE ENAM SEC14L5 WDR70 CUEDC1 WNK2 TMCC1-AS1 RUNDC3A PDE9A LRRC27 DNAH14 AOC1 AGK WDR90 MICALL2 CLPTM1L TMEM41A MUC6 ZNF391 OSBPL2 FSIP2 EXOC4 GPER1 ZNF766 ITGB4 MAD1L1 MRPL3 ENTPD6 ANKMY1 TARS2 B3GNTL1 PKMYT1 CAD PTGFRN ZNF605 FADS2 NIPAL1 R3HDM2 OSBPL7 BTBD2 DCLK1 EXOC3L4 PPIL2 LAMB4 DDX51 PAK1 KRT18 SLC39A11 OSMR ARHGAP39 CD300A PACS1 PHF12 GOT2 SUN1 GIPR PGBD2 SYN3 ENPP3 KRBA1 PSMG3 PLCG1 NAPEPLD LZTR1 CHCHD2 ZNF687 CAPS2 YDJC ADNP TACC3 ATP9A MAN1B1 XYLT2 ARHGAP32 HIRA MAPK13 TRIM37 TMTC2 JMJD4 HECTD1 STEAP1B TCEA1 DLK2 GUSBP1 GFM2 EPB41L4B NRF1 FAM207A ITGB2-AS1 MT-TH CCDC159 EFCAB8 OLFML2B KIAA1549 TCEA2 DHTKD1 SH2B1 EP400 MAN2A1 TTLL3 C12orf65 FBXO22 NRXN2 LRRC59 KRT8 NOC4L ANKS3 SNAP47 LRCH4 LRIG1 PIP5K1A LRRK1 IGHMBP2 WDR27 CBR1 CNTN2 ZNF286A PRSS8 CEP85 MICAL3 LHX4 FAM3C HDLBP RTEL1 BLVRB SYBU CDK5RAP1 ZNF404 ST20 MROH1 SAMD4B SNX19 TCF25 LINC00240 CIAPIN1 GNA12 BCAS3 GNE C1orf159 TRIM67 ANKS6 ZNF341 TSNARE1 LINC00304 NPEPL1 NUP210 PI4KB WIPI1 PPP4R4 LINC00888 FTSJ3 ACIN1 ZNF740 NOS3 CFI DYNC1H1 SCRN2 NSUN5 BCL7A COMTD1 ST6GALNAC1 NOXA1 ZC3HC1 TMEM229B PSME1 GGA1 VAC14 CARD14 MCEE COL5A1 SMYD3 DUS3L LZTS2 TEFM DQX1 RPS6KB2 MTR MIR4273 HOMEZ PIGZ SHMT1	up	*
MIR6835_3P	0.0020754	0.0273620	0.4317077	-0.2299758	-1.331662	368	ATXN3 RDX RAB3C RCOR1 FYN OTUD1 QKI BMPR2 PRKAR1A KCNN3 AGPAT4 CIT TMX4 ARHGAP29 SSTR1 ATP2B1 DNAJC3 FOXA2 HECW2 LIFR PPP1R15B RAB33B GLS GPBP1L1 ZNF697 ADIPOR1 CLN5 TMEM123 SETD3 PDGFA EXOSC9 PRDM16 C14orf132 BIRC2 ZSWIM6 ADO REST PLEKHM3 ZNF24 UBQLN1 DOCK9 RBMS1 NR1D2 CTBS ACTR3 ELMSAN1 N4BP2L1 PPP2R5A CLIP4 PDE1C BACE1 SEC31A EFR3A RAB6A SNX3 KCNA5 RBPJ HSD17B13 NEK7 PLEKHA3 PPP6C CNTN3 TMTC1 LIMD1 ETS1 DDX17 UHRF2 RCAN1 MCM9 PIK3R1 CREB1 SLC10A7 GFPT2 MORF4L1 SRSF6 TTBK2 PBRM1 PHF3 CCP110 MAP3K2 HNRNPH3 MYOCD KAT2B FKBP1A OPN3 SCN7A MTO1 THAP6 GPD1L RBMS3 OSER1 TTC28 RNF38 DNAJB9 SYNPO2L KIF1B RORA DOCK4 C1orf52 SLC44A5 MED17 RABGEF1 SUGT1 MAPK1 EIF3L SH3GLB1 ATP1B1 CSNK1G3 BSG LMO7 FAM160B1 MTSS1 SCAF11 CAPZA1 GABPB1 PCDH15 FAM218A CNTN1 WDR26	down	*
HOXB4_TARGET_GENES	0.0004645	0.0099024	0.4984931	0.2607074	1.331291	943	MNX1 EPHB3 C1GALT1 MDM1 IGSF9 TICRR MCM10 AP3B2 XYLB IGF2BP3 TIMELESS C21orf58 DDIT4 LINC00941 NDC80 PLEKHA6 BRCA1 BET1 CREB3L4 MRPL46 HILPDA SAYSD1 TTC26 CEP70 EFNA4 CDCA8 FIGNL1 SMPDL3A SPATS2 TYMS NWD1 PLS1 COPB2 XPO5 VILL AVL9 ZWINT ZNF608 CCT2 DCTN2 LSM5 LMLN FAM220A AARS2 ASAH2B GOLPH3 MAP7 NLE1 STAP2 TP53BP1 PCCB COPG1 CLHC1 POLA2 SAE1 YKT6 GTPBP3 LARS2 ZNF860 ABCC5 ANKRD19P TTC22 ASPHD1 SETDB1 CCDC114 NME9 PKM LINC00511 PYCR2 AP1M2 LIG1 EME2 LINC00265 ZNHIT1 CCDC148 GET4 C7orf50 SCAMP5 FBL SLC25A39 RPAP2 MRPS11 EEFSEC FBXL8 ETFA TST NOL3 C4orf47 ZNF713 MGAT4B TFCP2 TULP3 COQ9 ZNF346 CNPY2 PPP1R37 TRIT1 CKLF RNF216 MRPL36 RASSF6 CMAS PPIL2 FASTK ASF1B MRPL37 FAM221A PABPN1 HDGF CENPJ CENPH ANKRD54 OAT NPM3 STAT2 MCAT MKRN1 ACTR3C SDCBP2 ZNF584 NARF PDK1 ANAPC7 POLR1C TNPO2 C16orf71 TAF6 METTL3 OARD1 SLC2A13 MTBP SNRPE GOLGA5 ABHD4 ANXA2R KPNB1 TPD52L2 RNF44 CHCHD2 NET1 POLR2H MZT2A GOLGA3 ZNF687 ELMOD3 CEP63 CCDC142 DPP3 TUBG1 CCDC134 SNX27 C19orf47 TRMU TRADD NMRAL1 MRPS34 YIPF3 ZMAT5 IQCG LRRC8D LMF1 MORN2 DNM1 CENPQ POMT2 HECTD1 ANP32E PKP4 MAPK10 ASNS LCLAT1 SYNGAP1 IQCH SIL1 NUP85 ZBTB45 CLTB RBM33 IP6K2 YARS2 BCDIN3D-AS1 DHTKD1 KDM3A KLC4 EFCAB7 L3MBTL2 STOML2 PLD1 WDR34 RIN1 ZCCHC17 FBXO22 ZNF497 HMGB3P22 USP2-AS1 CHMP4C TRIM56 KRT8 RPL7L1 RPPH1 SURF2 ANKS3 UIMC1 PYGO2 SLC35A3 CACNB3 NSD1 RTEL1-TNFRSF6B GINS3 LRCH4 STMN3 AATF PFKFB4 CYP4F12 CCNG1 WDR27 ANK3 GOSR2 MST1P2 NUP62 FARSA NDUFV1 B9D1 NCDN ULK4 PRIM1 MLXIP RTEL1 SYBU ACKR2 TTC31 WDR4 HK2 OSBPL10 N6AMT1 TTC1 STK25 TRIP4 NBR1 R3HDM4 TRIP6 FBXW11 ST20 SAMD4B RARRES1 KIAA0825 SNRNP70 SLC35B3 UNKL MXD3 DIP2B ATG2A UQCRQ ZNF131 CIAPIN1 POLR1B PNKP SYNRG GOSR1 MAPK8IP3 RPN1 POLR1A EIF4G1 E4F1 CELSR3 TIMM44 FIS1 LEMD2 MRPS27 ARMC10 SART1 RAD1 SLC39A1 NAT10 MUC1 TK2 TRUB2 ILVBL BRSK2 PPP1R14B PTPN13 SART3 DDX41 ACTR5 FTSJ3 TRPC4AP SETD5 PRKAG1 ALKBH2 ZNF629 PARP2 RNF14 TPM1 TMEM62 SHROOM1 ZNF740 TNFRSF1A WRAP73 METTL4 SH3RF2 RAB40C TRIM52 CRAT EIF2B1 ZNF598 PCNT NOXA1 NOD1 FOXP2 SCAMP4 CYB5RL MRPL43 LTK DLGAP1-AS2 NSL1 MECOM TM9SF1 MARVELD2 GATA6-AS1 ARHGEF19 LINC00271 SERTAD4-AS1 GCC1 PGAM5 CCDC24	up	**
MIR33A_3P	0.0019821	0.0264111	0.4317077	-0.2290780	-1.331188	371	RTKN2 AKAP5 SASH1 DENND5A CPEB2 ATXN3 SNX10 CLEC12A CLDND1 ST6GALNAC3 RUNDC3B CCDC88A RASAL2 CITED2 S1PR1 NR3C1 CD1C NFATC3 FAM49A PPM1D CD8A CCNL1 SH2D6 NCEH1 ANXA5 REV3L CAV2 SLC7A11 MS4A1 PPP3CA EPM2AIP1 HNRNPU UBE2D3 GLDN FABP5 KCNMA1 MPEG1 LIMS1 ZFAND5 OSTF1 MAP1LC3B MYO1B SPAG9 UBQLN1 NPAS3 GPR85 AQP4 SHE CCND2 CLK4 PRF1 CCSER2 DNTTIP2 CPT1A CUL5 NUS1 AFF1 LIN54 SPIN1 CREBRF ELF1 PHTF2 PHACTR2 EBAG9 NECAP1 SF3B1 CD48 CNTN4 FOXN2 DHX15 HSPA13 CREB1 KBTBD8 CXCL5 PELI1 TSHZ3 PEA15 STRN TBRG1 CNOT7 PCDH17 MRGPRF ACADL GNA13 ARAP2 HSPA2 INTS6 RPP30 YAF2 CEP170 SEC63 FBXO30 DIXDC1 MEX3C GPD1L JMJD1C SCAI FAM126B MMD RORA NRP2 GRB10 YTHDC1 PSIP1 TMEM184C TMEM50A CFL2 CCDC112 CENPC ZNF800 CLOCK PRKCH	down	*
MIR548AC	0.0004029	0.0088414	0.4984931	-0.2244333	-1.331172	516	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA	down	**
AAGCCAT_MIR135A_MIR135B	0.0035905	0.0393860	0.4317077	-0.2364178	-1.325457	287	BMPER BACH1 RASAL2 LONRF1 QKI BMPR2 MKNK1 RGPD5 C3orf70 MOB1B HPS5 SEMA6D LDLRAD2 BZW1 LINC00315 LCP1 GATA3 AKT3 ARHGEF2 HNRNPU ROCK2 FOXO1 KCNMA1 SDCBP PPP6R3 ADO KLF4 PRKD3 ADAMTS9 GRK5 ST7L GPR85 ATF3 CCND2 FRMD4A ELK3 INHBA PPP2R5C KPNA3 BACE1 CPLX1 NCOA1 SIAH1 FOXN3 TOPORS SERTAD2 PHTF2 WSCD2 KCTD12 SP3 FBXL16 ENTPD4 SNRK GPR3 CTTNBP2 PELI1 YTHDF3 SLC35F1 EPHA3 NUP153 DUSP5 CNTNAP1 PGGT1B PHLPP2 RNF138 ZNF143 FKBP1A TRAPPC8 BRWD1 PDE4A SKI MTUS1 PDE8B NR3C2 CREG1 TLK1 SHISA6 EVI5 MIER3 ZBTB44 PHOSPHO1 PSIP1 JDP2 KALRN ZNF385B DRAM2 ATP1B1 API5 TRPM7 WAC MTSS1 ZNF362 PDE7B MAN1A1	down	*
ID1_TARGET_GENES	0.0005724	0.0114071	0.4772708	0.2595303	1.324800	998	HS3ST1 HOXB-AS3 CEP89 TICRR GPT2 ASCL5 CHEK2 PDCD6 ABCA17P CCDC127 NPAS1 TTF2 GCNT3 NUDCD3 NDC80 PLEKHA6 NMNAT3 IFI27L1 CDK4 IFT122 TOMM34 TPX2 GAPDH PLEKHA7 C19orf57 HNF4G MARVELD3 CAND1 AP1G2 KAZALD1 DNAI1 SIPA1L3 PPP1R9A SMARCD3 EXO1 C19orf48 DLG1 SMARCC1 XPNPEP3 ANKUB1 SDHA RPAP1 ZFYVE27 DCBLD2 F2RL1 STAP2 TP53BP1 PCCB TSGA10 TIGD4 FANCA BRAT1 CCDC77 FBF1 SPTB THBS4 C1orf226 POLD2 GTPBP3 TMEM132A LARS2 TPR ASCC2 HOXC6 ZNHIT6 EIF2AK1 LMNB1 LINC00511 MCCC2 TRIM11 PFN2 AP1M2 POLR3C LINC00265 ZNF786 PIH1D1 ABCB9 BRIP1 DDR1 RABEP2 BLM SLC18B1 RNASEH2B-AS1 LTB4R C2CD3 C4orf47 SLC25A10 GEMIN4 INCENP THOP1 GCKR TMED3 RASSF6 FAHD2A SUPT5H ANAPC5 CTDSP2 SSBP1 EXOSC2 CENPJ FAM135A AP3D1 C1orf112 XRRA1 SUN1 RBCK1 TCF20 KCTD13 SMG9 MRPL17 PMEL PODNL1 LARP1 PDK1 ANAPC7 TSPAN31 ZNF775 MTBP SNRPE GOLGA5 CBX1 CCDC57 PA2G4 IRF6 DHX34 MPI DNMT1 UPP2 CEP63 TAPBP TBC1D9B RHOC UQCRFS1 VIPAS39 SLC35C2 DCAKD WDR53 FAM47E-STBD1 FOXRED1 GSS SNRPA MNS1 AARSD1 MBD4 DHRS4-AS1 S100A16 LONP1 CCDC151 KIF22 GPRC5C EPHB2 TIGD6 DUSP12 MORN2 RHBDD3 MLEC CSNK1G1 MGMT SOX2-OT LMTK2 OS9 CCDC146 MRPL4 PKP4 ACAD10 SLC22A23 TRIM32 CCDC51 C15orf41 CKMT2-AS1 SYNGAP1 CDK13 NUP85 ZBTB45 ENC1 TMEM232 ELAC2 NIF3L1 BCDIN3D-AS1 CCDC137 TNK1 EFCAB7 RGL4 MEI1 L3MBTL2 DGKA KIAA0100 MAN2A1 TTLL3 DUS1L TCTN1 NRXN2 FITM2 PHYKPL CLINT1 KRT8 MGME1 PLEK2 MYO5C EML6 RAI14 CENPT NSUN6 DHX8 NOSIP BSN LRRC17 HEATR1 ADD3 EFHB TMUB1 AATF CLDN16 KATNB1 DNAJC21 RTKN PDIA4 SUGP1 RRP36 SH3TC2 U2AF2 MST1P2 NUP62 LRRC14 SPAG4 AMN1 BCL9 MCRS1 GLIS3 PRR11 PRDM10 NFRKB CISD3 ZNF70 DDX54 SNRPD2 DENR MRPL55 TXNL4B GTPBP2 ABCF2 ACKR2 ABHD10 BMS1 TNKS1BP1 CAPN10 TPGS2 PPP6R2 ZNF217 SAMD4B SRP9 SNRNP70 SNRNP200 RPRD2 FAM118B LINC00240 NDUFS8 POMK METAP1D DIP2B ALKBH6 UQCRQ ZNF131 CIAPIN1 SMC2 BCAS3 B4GALNT3 RPN1 MAU2 ALG1 NMT1 PAICS FIS1 CHERP FBXO34 RANBP3 MRPS27 SLC36A1 CYSTM1 FBXO45 ANKRD46 SFXN5 ZMYND10 RAD1 CCDC91 RNF32 RABL6 NLGN1 TTLL5 TRUB2 ILVBL CALU MOK DDX41 BRIX1 ATP6V1E2 FAM219A TRPC4AP PPP1R16A NCAPH SLC33A1 CYHR1 RNF14 TPM1 MEIS3 FAM47E SUMF2 DAZAP1 TMEM62 CEP290 APEH METTL18 HEXIM2 FGFBP3 DHX57 ARMC2 KLK10 TNFRSF1A ZDHHC13 MAN2C1 KLHL42 C4orf48 TRIM52 AKAP9 NIT1 PARL CNKSR1 RPL36 ZC3HC1 LPCAT1 FOXP2 USP35 GGA1 KTN1-AS1 EDC4 TOMM40 MECOM MCEE NHP2 STARD10 CCS RAG1 NPM1 IMP4 TEFM MSH6 RNF40 ZNF425 KCNK1	up	*
ZNF260_TARGET_GENES	0.0016517	0.0230023	0.4550599	0.2631756	1.323970	687	HMGA2 MEGF10 RUVBL1 DNAH2 PARPBP GMDS FBXW8 ZMYND8 CHEK2 C17orf75 STOX1 TSHZ2 DDIT4 TTC25 RAB3IP TSFM METTL1 TUBB2B GINS1 CDCA2 NOL12 ANKRD24 TTC26 NUF2 WDR70 ZNF221 ZNF283 ZNF608 COQ3 UQCC1 LSM5 NUB1 TAMM41 NME1 AARS2 TOP3B TMEM41A KCNH2 ZNF391 C9orf116 FBXW9 CCDC77 GTPBP3 RBM28 MRPL3 ANKEF1 EMG1 TARS2 PSMG4 EME2 HEBP2 DNAJC9 THAP10 RABEP2 DET1 MNAT1 TFCP2 OSBPL7 UQCR11 GEMIN4 TXLNB SUPT5H CBX5 ANAPC5 PABPN1 CDK12 SSBP1 ZNF260 C1orf112 CCNJL MRPS2 ENPP3 KLHDC9 TSPAN31 TMEM79 PSMG3 TNPO2 RNF207 SEMA3A ATAD3A RNF150 SNRPE ZNF827 PSMC4 WDR24 ANXA2R KPNB1 CHCHD2 GRAMD1A CCNE1 SMG5 NDUFA11 SEC16B ZNF233 GALK2 ADNP MTOR JOSD2 DHRS4-AS1 MRPS34 COG2 DNM1 COPS7B ZNF234 JMJD4 MLEC SOX2-OT CPE MTND5P11 LIN37 GFM2 ZNF282 POLD1 FAM207A PRRG2 CCDC159 ZBTB45 POLB NIF3L1 GEMIN6 LSG1 EFCAB10 VPS25 ASB6 FAF1 DUS1L FBXO22 FAM136A ACLY PPP1R3D PPP6R1 KRT8 MRPS33 RPL7L1 UBL7-AS1 RAI14 NOSIP SLC38A7 NMNAT1 ANKRA2 SNRPD1 SNAP47 TFAP4 MRPL53 SLC35A3 RTEL1-TNFRSF6B POLR2J3 STMN3 NDUFS7 YIPF2 RCC1 IGHMBP2 ZNF780A MST1P2 AKAP6 GNAL ZNF580 ZNF622 NME1-NME2 PRPF18 ZNF224 BCL9 TSC2 RBM42 ZNF195 BANF1 RTEL1 POLR3B TUBGCP4 STAT6 CDK5RAP1 ZNF404 PRPF31 BMS1 TRIP4 GTF3C5 SAMD4B MRPL21 LINC00240 TMEM101 AURKAIP1 SNUPN SIRT6 GOSR1 ZNF793 POP4 ZNF205 ZNF354B BPNT1 MRPS27 PIGL DCDC1 PIGQ MRPL48 NDUFB7 CLASP1 DDX41 ALKBH2 TTC5 SLC33A1 INO80B ZNF554 METTL18 HEXIM2 MORN4 SETD1A ANO8	up	*
U2AF2_TARGET_GENES	0.0017392	0.0239451	0.4550599	0.2594028	1.322283	884	PPM1H PRLR SPICE1 WFDC3 DNAH2 GMDS RPGRIP1L PDCD6 ZNF84 XYLB CCDC34 APOLD1 IQCE TTF2 CCDC113 BRCA1 CREB3L4 FANK1 CDK4 IFT122 DBF4B AP1S1 NUF2 ALDH18A1 WDR70 NBR2 KNOP1 NOX5 EIF3B ZFP64 COX11 C6orf132 TOP3B WDR62 RSPH1 NEURL2 BBS1 RND2 SPAG16 DPY19L2P2 TP53BP1 FOXJ1 AP4M1 TIGD4 CCDC13 CCDC77 BPHL AGT CBX3 C20orf96 ODF2 YKT6 LARS2 MCM7 DPCD SPEF2 RNF157-AS1 EFCAB12 GCAT SETDB1 NME9 ENTPD6 WDR73 GPSM2 PLTP C7orf57 TARS2 BCL2L2-PABPN1 C7orf50 THAP10 DNAAF3 SNAPC4 COMMD4 SYMPK STXBP4 ENTPD5 TRIT1 PES1 NRTN POLN EXOC3L4 NRSN2 KIAA0556 C2orf50 LRGUK LRRC6 CDK1 DNTTIP1 SSUH2 PICK1 TTLL9 WDR54 KIAA0753 AAGAB REEP6 ZNF815P CCNJL TMEM8B LRRC9 TCTN2 ENPP3 ZNF584 KLHDC9 POLR1C ZNF775 TNPO2 TTC23L TAF6 THAP8 SF3B3 KIAA1211L LRRC56 CCDC57 ZNF827 VPS72 TMEM231 CASC1 ZNF324B KPNB1 CHCHD3 NET1 CATSPERG TBC1D9B NPHP1 C19orf44 SLC35C2 SATB2 NEK10 DNAH7 TSNAXIP1 ADAT1 MNS1 MAN1B1 POLL MBD4 RAD9A YIPF3 GALNS GPRC5C CCDC130 SUDS3 MORN2 COPS7B UBE2Q1 PCSK4 NFATC4 COLEC11 MLEC IQCK FZR1 MAPK10 CLTA LAMTOR2 LIN37 ZSWIM1 TMEM186 COG4 FUCA2 IQCH SND1 C12orf73 CEP128 TYRO3 SCNN1G PLEKHB1 TRAF3IP1 NAIF1 ZBTB7B ATP13A1 SLX4IP GEMIN6 UBQLN4 EFCAB7 TMEM234 GTF3C1 UBE2O PSMB3 STOML2 CA11 CCDC30 EFHC1 ZNF497 ZNF76 UBXN6 PPP6R1 BAD KRT8 COMP ZNF432 MCM5 ANKS3 WDR35 SNRPD1 DYNC2H1 NEK4 ZNF599 FBXO36 NDUFS7 SLC1A5 PALM3 ZDHHC11 LHPP U2AF2 PATZ1 PRMT5 ARFGAP1 STRBP ZNF580 SPAG4 INTS8 PYCR1 GLO1 MAP3K14 GABPB1-AS1 MANBAL RFC5 CSNK1G2 DOHH YBX2 PAK4 CTU1 STAT6 CCDC181 BMS1 TRIP4 ZNF292 LRRC71 RUNDC1 METAP1D TBC1D32 UBAP2L CASC2 ZNF142 SYNRG TCF3 C1orf159 PFDN4 E4F1 RHPN1 DHRS3 LRSAM1 NMT1 TRUB1 SLC38A4 CYSTM1 RHPN1-AS1 GPN1 ARMC10 SLC39A1 DDB2 ZNF253 NLGN1 STK11IP PLXNB1 ATG4B PTPN13 MZF1 C12orf10 TRAPPC6A H1FX-AS1 NQO1 CNPY4 EIF2D STK33 DHX57 POLRMT DNAAF1 ZDHHC1 MED22 LUC7L3 PCGF2 SFXN2 DHDDS TEKT1 NSUN5 ITGB5 PDK2 POFUT2 HRAS ZNF649 RANBP10 GCC2 RPL36 PEX11A ZC3HC1	up	*
MIR302C_5P	0.0014962	0.0221518	0.4550599	-0.2223771	-1.321575	474	RTKN2 EDNRB ZC3H12C ST6GALNAC3 BMP2 COQ2 EMCN GPCPD1 SFR1 IDI1 NR3C1 PFDN1 RCHY1 TMX4 ZEB2 UBR3 KIAA0355 DNAJC3 B3GNT5 LIFR LATS2 BZW1 ECHDC1 PBX3 FZD4 SLC7A11 DACH1 SRSF2 HNRNPDL SPTBN1 ZFYVE16 ZEB1 TFRC ATP6V1B2 PRDM16 AMOTL1 NRARP MTMR6 ZCCHC24 REST TNFSF15 STK17B THBS1 MAP1LC3B ADAMTS9 SOCS5 FBXL3 NPR3 UBQLN1 PDE8A TADA2B ATP6V0D2 RECK UBE2B PIK3C2A CPT1A CUL5 LMBRD1 CNOT6L TGFB2 PDHX FLT1 CCNY PRDM11 ELF1 VPS37A LRRTM2 DDHD1 CTSS PHACTR2 RASSF10 NSMCE2 MSRB3 CYCS HSPA1B ARHGEF10 NXPE3 FOXN2 APBB2 PNPLA8 TTC14 FRYL OSM LPCAT2 GTDC1 TCP1 TSPYL1 CGGBP1 WDR7 CDK17 PTP4A1 RIN2 NAA16 IRF5 CHORDC1 NUP153 STRN SBF2 GNAI1 ATP6V1A NAB1 IRS2 MAP3K2 KANSL2 LTBP1 EMC4 MBNL1 INO80D HACE1 BMP2K RBL2 ANKLE2 RNF138 SESN1 CEP170 LRP12 CYB5R4 TAB2 TTLL7 PTCH1 BRWD1 ZDHHC21 CREBBP LYSMD3 EDN1 B3GNT2 FAM126B GTPBP8 RORA DOCK4 ZFPM2 SFPQ EIF4A2 SMAD4 MIER3 HNRNPH1 PSIP1 ACVR1C RBMXL1 CDKN1B SPPL2A	down	*
MIR6504_3P	0.0040352	0.0425552	0.4070179	-0.2303782	-1.320578	328	CPEB2 SNX10 EMP2 ST6GALNAC3 PTPRB RASAL2 MS4A15 QKI BMPR2 TGFBR3 MOB1B RCHY1 CNST TRA2B RAB33B BZW1 NLK PRSS12 CAV2 SLC7A11 EIF4E LHX6 MPHOSPH6 SPTBN1 MAPK8IP1 PDE4D ROCK2 TLE4 FOXO1 PPP6R3 KLF4 ITM2B PEG3 HAUS2 PLEKHM3 ANKRD10 GAPVD1 CYP20A1 RECK UBE2B CAPZA2 CCSER2 PRICKLE2 IKZF5 SIAH1 TGFB2 METAP1 YBX1 SGK1 CTSS KIF13A PHACTR2 NEK7 INPP5B SH3BP5 CNTN4 EEA1 HSPA13 IDS CREB1 CTTNBP2 NECAB1 HIVEP2 MAPK8 NAA16 DCK PDS5B RSBN1L TMEM230 MYOCD RIMKLB KAT2B ABI3BP ATAD2B INO80D RNF138 ABL2 CTTNBP2NL SFT2D1 NT5C2 RAB5A TMOD2 ARIH1 PTCH1 PSME4 SRSF10 RASSF8 DOCK10 SCAI FAM126B CAMSAP2 CCND3 SHISA6 SPATA13 EIF4G2 ABI1 REEP1 PLAG1 PEX14 TBPL1 GJC1 NR4A2 MAPK1	down	*
MIR182_5P	0.0005392	0.0109329	0.4772708	-0.2236520	-1.319621	468	EPAS1 RTKN2 COL25A1 EDNRB KLF13 ZC3H12C INSIG1 TMEM170B AATK TXNL1 BAG4 CORO1C VAT1L CITED2 AQP9 QKI ELMO1 MOB1B RFTN1 ACER3 TEX2 WWC2 SLC44A2 SLC2A14 HBEGF TACC1 RAPGEF4 EIF5 SPIRE1 CAMTA1 ZNF697 SLAIN2 PPP3CA FAM122A TNS1 PPP1R13B ARHGEF2 TAPT1 PRDM16 DENND6A LIMS1 SETD9 ZFAND5 THBS1 CEBPA MYRIP SPAG9 DOCK9 GPR85 SHC4 RECK RNF139 CCDC59 CUL5 GNAQ ZNF706 N4BP1 UBASH3B PAFAH1B1 TLL1 ACTR2 FOXN3 TOPORS SPIN1 VAMP3 CCNY MED28 APPL1 MITF SH3BP5 MAP4K4 SHOC2 FOXN2 RHOJ TBC1D12 SKIL SP3 PIK3R1 MBNL2 PRKCE GRB2 FAM43A CREB1 STX5 NUDT15 CGGBP1 PPM1F SPRY4 CD164 FOXO3 SRSF6 PIK3AP1 PDS5B ABHD13 CBFA2T3 RELL1 PPP3R1 TOB1 NRN1 PCCA INO80D INTS6 TNFAIP8 RTN4 JMJD1C B3GNT2 FAM126B MMD PAIP2 ANXA11 CAMSAP2 C21orf91 DAZAP2 DOCK4 GSPT1 SLC44A5 RAB2A EVI5 SPATA13 REEP1 SETX KLF15	down	*
AAGCACA_MIR218	0.0048803	0.0492118	0.4070179	-0.2303801	-1.319212	319	SLC24A4 SEMA6A SASH1 HMOX1 TRHDE KCTD9 CCDC88A RTN3 ELMO1 MKNK1 NR3C1 C3orf70 ZEB2 NUMB EDEM1 BRINP3 UBR3 NFIX TACC1 LIFR WNT2B FZD4 PEX5L PPP2R2A GPM6A FBXO8 ZMIZ1 MVB12B MAFG GAPVD1 SPAG9 SIK2 GPR85 SHC4 FRMD4A RNF139 WDR48 ADIPOR2 PPP2R5A OXSR1 GNAI2 AKIRIN1 PI4K2A FOXN3 RAB6A RPS6KA2 SERTAD2 SOCS3 MAGI2 RAB8B SEC14L1 ARL5B MITF VAT1 ZFP91 PIK3R1 MBNL2 PRKCE RAB8A ACSL1 PTP4A1 HIVEP2 PDE12 DUSP5 ZBTB11 GNAI1 KHDRBS1 DYNC1LI1 ATXN1 CSDE1 KCNA3 TOB1 MBNL1 DBNDD2 ARPP19 INTS6 WDR1 RTN4 SRP72 STAM2 HNRNPC CUL3 RET KIT RNF38 PRKG1 DLST SHISA6 PUM1 PURB BMI1 RAP1GAP MED17 PPP1CB ZFYVE26 JDP2 KALRN	down	*
ZNF10_TARGET_GENES	0.0038974	0.0417332	0.4317077	0.2632514	1.319149	633	PTGES MEGF10 DDX12P CEP89 CHEK2 C1RL-AS1 ABCA17P DROSHA FBXO27 PDCD2L CYP2J2 SEMA4B TTF2 METTL1 ZFHX2 EFNA3 C4orf50 ZNF285 FLAD1 SEC14L5 ACAD9 WDR70 ZNF714 GOLGB1 KCNT1 ARHGAP33 GRHL3 FBXL19-AS1 ZFP64 TNC NUB1 KAZALD1 WDR62 DYRK1B CEP55 BBS1 STAP2 FBXW9 POLA2 GTPBP3 IRF3 MCM7 ADAMTS13 EFCAB12 CCDC114 DCDC2 FANCD2 GPSM2 SEC61A1 TARS2 POLR3C SLC9A3R1 SCAMP5 THAP10 MST1R RABEP2 FBXL19 MTG1 PHB ALDOA OSBPL7 COQ9 DHRS13 PARP1 ZNF229 NCAPG2 CMAS SSBP1 KCTD7 GOT2 ACP6 STX18 REEP6 TRIM2 PSMB5 STAT2 SEC61G PMEL FAM98C KRBA1 TMEM79 CCDC57 MAD2L2 VPS72 ANXA2R ZNF500 CHCHD3 CAPS2 ILF2 DLGAP5 PDCD11 IGLV6-57 SMG5 NDUFA11 PSMA5 ZNF133 EFCAB2 SNRPA MC1R OSBPL3 KIF22 ROGDI UBE2Q1 PCSK4 SCN8A JMJD4 ATG9B HIP1R TJAP1 AGPAT5 ITFG2 TCEA1 SPAG1 STX18-AS1 KIF20B DLK2 TMEM186 ASNS TM9SF4 NTN3 BCL2L12 CHD5 FAM200A CCDC159 POLB ENC1 PPIEL EFCAB7 LIMA1 GOLM1 UBE2O PPHLN1 TUBG2 ASB6 TCTN1 ASCC1 UBXN6 CDR2 ABCA7 ARVCF KDM4B ZNF160 PPCDC CYP2S1 LPCAT4 HHLA3 ANKRA2 SNAP47 C5orf22 TBC1D16 PRSS16 CREB3L2 TTLL6 SMARCC2 TCHP GOSR2 PRPF18 CAPN15 RPS26 ANAPC2 CCDC167 PAK4 STAT6 HOOK2 ARRDC1 ZNF292 ERGIC1 ZNF217 TEPP MICU1 TMEM101 PTPRF SNORA14B TBCB CASC2 ALKBH6 SLC12A2 ZNF131 CIAPIN1 TARBP2 SYNRG CENPE FZD3 POP4	up	*
MIR9_5P	0.0015374	0.0225834	0.4550599	-0.2277281	-1.318925	412	TRIM71 SLC31A2 STAC CPEB2 PRKG2 LYVE1 SIK1 INSIG1 AATK BAG4 THAP2 LAMP1 EOGT TGFBR2 NFATC3 HPS5 DNAJC3 SGMS2 LMNA CHMP1B FOXP1 HIPK3 GLS GPBP1L1 TNS1 ANKRD29 ARHGEF2 YBX3 ITM2B SETD9 REST SLC7A8 ADAMTS9 DENND3 SOCS5 FBXL3 PDE3B M6PR CCSER2 PIK3C2A DSE SLC6A6 OXSR1 UBASH3B TBC1D4 CRIM1 BACE1 SEC31A CMTM6 CNOT6L PI4K2A C16orf54 PDK4 MCMBP MYO1C CREBRF SLC8A1 VAMP3 ID4 WASF2 KIF13A HCFC2 CNTN3 UTRN TMTC1 CPEB4 KCTD12 ADRA1A C11orf58 CCDC50 ATP11A NXPE3 FOXN2 RHOJ FYTTD1 HUNK KLHL18 PCGF5 FRYL ATL2 AP3B1 RALB PALMD PPM1F GRSF1 SLC25A24 RHOQ SORT1 DDHD2 VAV3 TESK2 KCTD10 MTMR2 PDE12 CNOT7 MAP3K2 COL15A1 MYOCD ANKRD13A RXRA ABL2 ITPRIPL2 ESYT1 DIXDC1 ZDHHC21 RBMS3 ULK2 TMEM109 FNIP2 FAM126B C21orf91 FAM13C TLK1 EHD4 SLC44A5 MIER3 STARD13 NAF1 ARHGEF17 TBPL1 HIPK1 ATF2 SLC19A2 CLOCK FAM8A1 FBXW2 DYNC1I2 CCNT2 PRTG TRPM7 PRDM6 TSC22D2 CAPZA1 ATOH8 TES CCNDBP1 DR1 MAP3K1 RNF111 B3GALNT2 NR5A2 NTAN1 ITGA6	down	*
TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497	0.0007049	0.0131505	0.4772708	-0.2194414	-1.315121	505	SLC6A4 WEE1 PNPLA6 SOWAHC CPEB2 PID1 BDNF QKI ZCCHC2 CDC42EP2 PLEKHA1 PRPF38A C8orf58 ARL8B CDC42 TGFBR3 OTUD4 NFATC3 SCARF1 ATF7IP2 PPM1D LRRFIP2 C12orf76 KCNAB1 SEMA6D UBR3 LATS2 CHRNE PLXNA2 C1orf21 BTG2 PBX3 RNF144B TMEM74B LUZP1 RNF125 LITAF BFAR DACH1 ZMYM6 MED26 ADRB2 AKT3 WNT3A SETD3 CNN1 SLC7A2 KDSR MAP2K3 AGO4 DUSP3 TLE4 EXOC3L2 SRSF5 PPP6R3 RUNX1T1 MGAT4A CADM1 CDS2 RECK CCND2 CAPZA2 SMAD7 PPP2R5C KBTBD4 N4BP1 PAFAH1B1 CRIM1 BACE1 TLL1 RASL12 RASGEF1B ACTR2 SIAH1 PIAS1 USP25 PDK4 MOB4 CREBRF SCN4B RYBP PDIK1L SGK1 COPS2 PPP6C VAT1 GLUD1 FERMT2 BAG5 PIK3R1 KLHL18 PCGF5 COBLL1 EGLN2 CASZ1 DEDD SNRK ACSL1 SPRY4 CDK17 CALM1 CD164 CHORDC1 CHPT1 STXBP3 DCAF5 ABHD13 CDC37L1 CBFA2T3 C16orf72 PCDH17 PIM1 CSDE1 PHF19 PLA2G15 PHLPP2 HELZ PITPNA RNF138 MOB3B SESN1 FGF2 PDLIM5	down	*
MIR6809_3P	0.0022867	0.0291188	0.4317077	-0.2224148	-1.312998	436	FFAR4 TRIM71 EPAS1 USP12 GREB1 GREM2 MBOAT2 PTPRB BMP2 ARRDC4 TMEM170B SLC10A1 AATK STXBP6 LDB2 DDX6 RASAL2 NEDD4L SLC39A8 INPP5A MEF2A USP47 ZBTB2 RHOA ERG SEMA6D ZNF385D SLC36A4 SLC25A17 TACC1 CHMP1B ANPEP PEX5L PPP2R2A SLAIN2 PLXNA4 HNRNPU PDE4D HPSE2 MYCT1 PRDM16 C14orf132 MEFV PPP6R3 BST1 PIP5K1B SETD9 THBS1 MYRIP DPH3 RIT1 RBMS1 ATF3 ELAC1 ADIPOR2 NCKAP5 CMTM6 CNOT6L CDKN2AIP FOXN3 ZNF426 SERTAD2 SYNPO2 DNAJC27 UTRN TMTC1 CPEB4 PDE5A CCDC50 FOXN2 PTGER4 BAG5 FBXO11 TTC14 SP3 PI4K2B KLHL18 ENTPD4 SNX1 NIPSNAP3B GAS2L3 BLOC1S6 GPRIN3 GPR3 SLC25A24 YPEL2 HIVEP2 ZNF175 STXBP3 DCAF5 ZBTB1 YTHDF2 ZNF844 ZNF136 SLC8A3 WBP2 ADAM10 INO80D AMD1 PDLIM5 SETDB2 SIK3 TOB2 ALDH2 RBMS3 TBCEL CUL3 DOCK10 SCAI PAK2 TMEM87A THRAP3 CREG1 SHISA6 EHD4 PURB HPCAL4 SPATA13 PAPSS2 MS4A2 ZNF326 REEP1 KALRN ACVR1C CDON CHML	down	*
MIR3133	0.0011537	0.0180109	0.4550599	-0.2248988	-1.312501	417	AKAP5 LPIN2 EDNRB TMEM170B HSD17B11 QKI HMGCR RGPD5 VAPA OTUD4 CBL MOB1B ZEB2 EDEM1 KIAA0355 NCEH1 LACTB SLC2A14 SLC36A4 HECW2 LATS2 MTF1 ZNF503 HIPK3 RNF182 CAMTA1 PAG1 DACH1 MED26 TFEC MYCT1 PDGFA FLI1 CYBRD1 TAPT1 CCDC82 PPM1K LIN7C PEG3 RUNX1T1 FMO2 TJP1 STK17B KLF7 ZNF24 ITIH5 ATL3 MGAT4A CADM1 CXXC4 ACTR3 PTGER3 CUL5 SLC25A32 ZNF706 RUFY3 LIN7A TGFB2 LIN54 USP25 CREBRF TMOD1 PDIK1L SYNPO2 NEK7 SRSF3 NECAP1 TMTC1 MITF DHX15 PCGF5 FSD1L ZNRF3 NAA30 RGS13 DENND4A MOB1A NECAB1 HIVEP2 PKD2 PPTC7 TRAPPC10 NAA16 CR1 SORT1 NIPA2 ATG2B TEX30 GNAI1 MAP3K2 C8orf37 INO80D RNF2 ARAP2 CEP170 SCN7A PARM1 TRAPPC8 ARIH1 TDRP IPO5 PSME4 ZDHHC21 CREBBP SRSF10 KLLN CUL3 BCAT1 CEPT1 SCAI EPB41L4A FOXJ2 DUSP7 DNAJB9 PRKG1 CAMSAP2 C21orf91 RORA	down	*
MIR526B_3P	0.0004847	0.0101600	0.4984931	-0.2195955	-1.311576	526	RAB11FIP1 EREG TMEM100 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 UTP23 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	*
MIR206	0.0025595	0.0315449	0.4317077	-0.2287474	-1.310518	325	TSPAN4 SOWAHC TBX3 TTC7B BDNF MMRN1 CORO1C CITED2 SLC25A30 NEDD9 CBL NFATC3 PFDN1 ZEB2 SEMA6D ZBTB4 TRA2B MCTP1 PICALM FOXP1 HIPK3 EIF4E DACH1 ASH2L PLXNA4 SFRP1 ANKRD29 HNRNPU FLI1 SLC7A2 CPED1 HMGN1 KLF4 THBS1 ZNF24 MGAT4A GPR85 PIK3C2A WDR48 PEAK1 NCOA1 C2orf69 NINJ1 SLC8A1 SLC25A25 ELF1 PDIK1L CREM UTRN LRCH1 HMBOX1 INMT ETS1 SNX2 DDX5 PRKCE MSANTD2 CAP1 SLC10A7 YWHAZ CEBPZ TAGLN2 CDK14 FOSB AZIN1 AP1G1 KCTD10 VAMP4 PDE12 ATP6V1A NAB1 MYOCD ADPGK HACE1 RNF138 INTS6 CTTNBP2NL WDR1 SEC63 RAB5A METTL21A ACTB MEX3C TIMP3 EDN1 RNF38 MMD SAMSN1	down	*
MIR548AN	0.0014027	0.0211388	0.4550599	-0.2256745	-1.309927	413	RAB11FIP1 PHACTR1 LRRC8C P2RY1 RDX SOX17 MTMR10 APIP VAPA FUCA1 TET2 CBL CIT PDE2A ATP2B1 MCTP1 FZD4 PPP3CA BAG1 ZYG11B AGO4 AGO3 LIMS1 PEG3 KLF7 FAM49B ATL3 RBMS1 NR1D2 NKIRAS1 VIM C9orf72 LBH PIK3C2A MBD2 KPNA3 CALM2 STK24 C2orf69 SACM1L SRF CLIC5 USP25 SERTAD2 UFM1 SPIN1 ARL6IP5 VAMP3 TMOD1 RAB8B ARL5B LRCH1 KCTD12 GLUD1 OSTM1 WTAP FERMT2 ATXN1L GRB2 ATL2 ZNRF3 TUBGCP3 TMEM128 BLOC1S6 AGFG1 YTHDF3 SRSF6 XYLT1 ING3 NUP153 PBRM1 TFEB HNRNPA2B1 STRN MAP3K2 PCDH17 PIM1 TMEM70 ANKRD12 GATA6 NRN1 PDE4B ETS2 ATAD2B INO80D ANKLE2 SCN7A EPN2 NSUN4 CREBBP SSH2 VSIG10 ING2 PAK2 B3GNT2 MTUS1 CECR2 FAM126B MMD FAM13B IQGAP1 EIF4A2 SMAD4 EVI5 MIER3 SPATA13 ZBTB44 PAPSS2 RABGEF1 FNBP1 REEP1 EGR1 CDON ENDOD1 USP30 SSB CLOCK ING1 MZT1 ITGB1 HP1BP3 PATL2 PRTG CD69	down	*
AATGTGA_MIR23A_MIR23B	0.0035248	0.0387936	0.4317077	-0.2278672	-1.309818	353	CPEB2 GREM2 TTC7B QKI ZCCHC2 ELF2 INPP5A TGFBR3 VAPA LAMP1 ZBTB2 TGFBR2 TRIB1 SEMA6D KCNK3 PICALM GLS CAMTA1 DACH1 SIRPA CRK SPRY2 PPP1R13B ZEB1 HNRNPU UBE2D3 ATP6V1B2 TBC1D9 RUNX1T1 ZNF423 GRK5 SCAF4 NPR3 CADM1 EPS15 AFF1 NCOA1 C2orf69 GPBP1 TMOD1 RYBP CDC40 PKNOX1 SGK1 PHACTR2 SEC14L1 CPEB4 MAP4K4 WTAP PTGER4 DHX15 FBXO11 CXCL5 SNX22 EGLN2 NDST1 CELF2 MSMO1 FOSB TSHZ3 PKIA NAP1L5 BTBD7 ING3 AZIN1 TGIF1 DUSP5 CBFA2T3 C16orf72 ATXN1 PHF19 MEIS1 WBP2 STX12 MICU3 CSNK2A2 PDE4B DBNDD2 CCNH ELF5 PITPNA BNIP3L UBE2D1 IPO5 MEX3C BRWD1 G3BP2 SSH2 KPNA4 STK4 CUL3 MTUS1 FAM13B NAA15 TLK1 SPOPL ZBTB44 PPP1CB IRF2 GREM1 ATP11B UBA6 LHFPL2 HAS2 CSNK1G3 CCNT2 PRTG OTUB2 HMGN2 MTSS1 AKAP12 ANKHD1 PAXBP1 IRF1 STARD5 SETD2 ROBO2 RAB11FIP2 PLCB4 FNIP1	down	*
ZFHX3_TARGET_GENES	0.0002733	0.0067985	0.4984931	0.2542567	1.309482	1385	ATP10B RPL13P12 RIBC2 HP HELLS C1GALT1 HOXB-AS3 CEP89 CDC45 TICRR PMFBP1 LYSMD1 NUP107 CCNB1 POLQ UBE2T PBK GCNT3 PIF1 RGMB-AS1 BRCA1 CDCA7 MRPL46 METTL1 GINS1 CDCA2 HILPDA DBF4B NOL12 STK31 STIL NDUFS6 TTC26 CEP70 NUF2 YEATS4 EFNA4 IFT27 CENPA ACAD9 ALDH18A1 ACOT8 CCNB2 MCM4 LSR RAD54B XPNPEP1 FBXL19-AS1 CKLF-CMTM1 ORC1 EIF3B PLS1 TDRKH GON4L LIPE-AS1 CAND1 FSTL4 NCAPD2 AVL9 CDK5RAP3 KRT15 CCT2 PCDHGA8 SPDL1 TNC LDHB SIPA1L3 GOLPH3L TJP3 C5orf34 POLR3A PLEKHG1 BZW2 HMMR C19orf48 SMARCC1 ZNF391 RPL4P4 EMC9 AP4M1 TPBG CCDC77 TOP2A EXOC4 RPL32P3 CCT5 RFXANK AURKA C20orf96 GTPBP3 MT-TY KIF2C MCM7 MAD1L1 E2F2 CENPW POC1A HYDIN CDCA5 PRKDC RNF43 SETDB1 AMACR ERAL1 SLC4A11 KIF11 MCM3 CDC25C ZNF785 TARS2 ANG RNFT2 SMYD5 LRRC66 SIDT1 HPR ZNHIT1 ZNF786 PEX26 ORC6 ACTL6A MAD2L1 NFYA KIF3C THAP10 DNAAF3 MRPS11 LRRC61 FBXL19 GRHL2 MRPS30 PHB FBXO16 CNOT3 ALDOA C4orf47 MGAT4B SPRY1 TRIT1 DYRK2 PSRC1 DDX56 CKLF CKS1B MRPL36 EFCAB11 NUSAP1 TMEM106C HARS2 MRPL37 KIAA0556 ANAPC5 KRT18P31 WDR5B SSBP1 ZNF440 RFWD3 PICK1 CCT3 NUDT2 KIAA0753 PHF12 ANKRD54 POC5 DGAT2 WDR31 AP5Z1 PMEL BPGM ACTR3C DHX33 TRIM41 KSR2 NUP205 PSMG3 POC1B TAF6 METTL3 RNF207 OARD1 SLC44A3 MTBP NOP2 TMEM231 CENPP C9orf43 IFT52 UNC45A ZNF692 RANGAP1 CHCHD2 MYO19 DNMT1 ZNF687 ACBD6 MOV10 UBFD1 ILF2 CDC23 SATB2 NADK2 SNORA70 NDUFA11 VPS41 DNAJA3 ADAT1 MNS1 FHIT AARSD1 DHODH PTGES2 GPRC5C MRPL11 IQCG TIGD6 COX7C TK1 C1orf131 NFATC4 ZNF239 ARHGAP5-AS1 CENPQ RHBDD3 MLEC SOX2-OT MTND5P11 VIL1 ITFG2 MAPK10 ZSWIM3 ZSWIM1 KRBA2 GFM2 SYNGAP1 SLC9C2 C12orf73 FXYD3 NUP85 PRRG2 MT-TH CCDC159 ENC1 ELAC2 SLX4IP NR6A1 CENPK CLDN12 EFCAB7 LSG1 GTF3C1 LINC00910 PWWP2A PSMB3 MT-TR TMEM106B ORMDL2 RPRD1B CENPM RIN1 LINC00467 CA11 SIRT4 MAN2A1 EFHC1 ASCC1 BCL2L1 HMGB3P22 SRRT FANCM MRPL24 PLEK2 BLCAP MRPS33 ANKIB1 DYNC1LI2 TBCA WDR83 RPL7L1 UBL7-AS1 MED24 PRMT1 NOSIP USP21 KPTN ZNF783 ANKRA2 TDP1 ZRANB3 SNRPD1 UIMC1 PARP14 EIF3D HAX1 RAB3D LRCH4 KATNB1 EXOSC5 MRPL51 RGMB RCC1 CCNG1 ATAD2 TCERG1 GNAL KLHL7 NUP62 MICAL3 GLO1 MSH2 MAP3K14 RBM42 HDLBP TMEM117 CISD3 BBX ECH1 SCNM1 RNF121 TXNL4B DOHH NAV1 CCDC9 ATOX1 N6AMT1 TRIP4 NBR1 MTIF3 ZWILCH TOMM40L FBXW11 ARHGAP5 GTF3C5 SAMD4B NDUFA8 NME7 FAM118B SNX8 AGBL5 ATG2A ZNF131 CIAPIN1 SMC2 GNA12 BCAS3 TARBP2 BCL6 TMEM260 CENPE POLR1A ANKMY2 PRPF3 FIS1 BPNT1 MRPS27 PPIA UBE2C CYSTM1 PNN GPN1 DCAF11 MRPL48 CCDC91 LXN TK2 CLASP1 TRUB2 FAM222B PTPN13 SART3 ZNF33A C12orf10 MSANTD4 ACSL5 IFI16 ANKRD11 TMCO6 CYB5B CLNS1A SLC33A1 CSTF1 COPE KIAA0586 TOMM7 DNAL4 RTN4IP1 CNPY4 INO80B RPL23A PLAC8 VPS18 MORN4 PDXP SETD1A MRTO4 MED16 WDR55 MBTD1 PPP1R13L PDK2 TFG UTP18 PTPRK CRAT AKAP9 TMEM259 CNKSR1 ZC3HC1 PNPO HINT1 ABHD2 TNPO3 NFE2L1 GGA1 OPA1 DLGAP1-AS2 MEGF11 TOMM40 SLC2A8 ZNF774 MCEE SLC4A1AP GLRX5 ZNF77 NPM1 IMP4 MTMR4 BTN3A1 MTR RPLP0 RUFY1 SLC27A5 CACTIN IMP3 USP49 DMTF1 AP2A1 NDUFB2 WDR89 CCDC86 NAE1 SMAD3 HNRNPAB PLOD3 MTF2 TXN2 LRPPRC AFMID TIMM9 PSMD3 PPP2R1A STRIP1 INTS9 DHX38 CALM3 BNIP1 ORC5 PAN2 COX6A1 EVI5L DDX49 PLEKHH3 SLC12A9 KIF3A PAWR FIBP CCDC124 RAB4B ZNF691 COQ4 GLCE ZNF839 STMN1 ZCCHC7 OIP5 TMEM14A SLCO4C1 SNHG10 MSL1 IK HNRNPA1 MPLKIP ABCB8 ACOX2 SUCO ZNF460 DAD1 NDUFA9 WBP1 KLHL20 HMBS CLTC KHSRP BUB3	up	**
BPTF_TARGET_GENES	0.0014051	0.0211388	0.4550599	0.2569979	1.309218	881	CCNO CPHL1P PRR15 KIF12 PRLR KCNMB2 ABCA13 MEX3A EYA1 RUVBL1 BDH1 TFAP2A NUP107 ANKFN1 IGF2BP3 UBE2T C17orf75 MUC4 DDIT4 PHF14 RGMB-AS1 STAB2 ECE2 METTL1 LCN2 XKR4 FABP6 ANLN COL28A1 ASPM EIF2B5 CEP70 NUF2 YEATS4 ALDH18A1 ECT2 CUEDC1 TFDP2 TRIB3 STC2 C4orf19 CYP46A1 GALNT10 PLS1 CLCN2 KIAA0895 CAND1 DZANK1 MRPS35 KCNG3 LDHB GOLPH3L CEP250 CLDN1 CASP2 TMEM41A BZW2 DLG1 KIF23 SYTL2 BICD1 FOXJ1 IGF2BP2 FRS2 KCNMB3 ZNF766 MAD1L1 CPD ABCC5 SMYD2 RNF43 WNT1 ERAL1 MRPL3 TRPT1 SNHG11 LINC00511 XXYLT1 SOX4 SARS2 SPINT1 DNAJC9 PA2G4P4 SCAMP5 EHHADH ABCB9 MDM2 TMEM63A BACE2 MGA ETFA INPP4B LRRIQ1 LRRC45 NOL3 RGS4 TRPV4 NRG4 ALG3 C7orf26 R3HDM2 RECQL5 DDX56 TNIK GPX8 RNF216 MSTO2P SIDT1-AS1 ACVR2B-AS1 TMEM106C LRRC6 CTDSP2 EXOSC2 EEPD1 PLCH1 TNK2 GMNN SRCIN1 NPM3 PGBD2 TRIM2 ZNF815P PMEL TRIM41 PSAT1 DPH7 ANAPC7 POC1B CCDC57 FOCAD RAPGEF5 SRD5A1 DNAJC7 KPNB1 EFTUD2 POLR2H POFUT1 THNSL1 VWA5B2 SNX27 VPS41 GALK2 ZNF133 MBD4 SLC37A4 TIGD6 ENAH ESCO2 SOX2-OT SLC22A5 SRGAP1 DUSP8P5 HECTD1 MTND5P11 ANP32E ACAD10 MAP6D1 SPA17 TMEM186 RPS7P11 KRT19 CDK13 PSMD2 MT-TH JTB POLB ZNF140 TCEA2 DNASE1 NR6A1 PROX1 LSG1 PWWP2A PSMB3 KCNB1 AGBL2 PLD1 TCTN1 FAHD1 HMGB3P22 RPA1 CLINT1 ASRGL1 FCHSD1 CAPRIN2 HEATR1 SPINK5 RABEPK PARP14 TBC1D16 PIP5K1A SKAP1 MYEF2 PIGX RGMB SUOX SLC1A5 RAP2B ANK3 C1orf122 DDX55 COPZ1 STRBP INTS8 PYCR1 SUV39H2 FCF1P8 RPS26 ULK4 SNORA60 DDX54 HEATR5A RPL9P29 RN7SKP296 RFC5 RNF157 PDAP1 STAT6 CDK5RAP1 TMEM44 ARRDC1 RAD51 TNKS1BP1 TRAPPC9 RPL6P7 GRAMD1B MROH1 ENKUR ZNF621 GRM6 WDR49 TCF25 TMEM101 NUBPL RNF7 TNS3 UQCRQ ZNF131 GNA12 TARBP2 EIF4G1 SRCAP FZD3 CLNK MTHFD1 SRPRB TRUB1 MCF2L2 KDM5B TIMM44 RFNG RNLS RN7SL381P NAT10 NLGN1 SH3GL1 CLASP1 DDX41 MTG2 KLHL2 SETD5 RAD51-AS1 FBXL18 LYPLA1 GRIP2 SLC33A1 CYHR1 NDUFAF6 LASP1 VPS26B RPS20P15 DNAAF1 PSTPIP1 MIOS ST8SIA1 SPIDR	up	*
MIR3662	0.0001353	0.0039660	0.5188481	-0.2100768	-1.308672	789	RTKN2 IL1A ST8SIA6 OSBPL11 OSBPL1A ZC3H12C LRRC8C PRKG2 RDX CLDND1 RAB3C LRRFIP1 PTPRB RUNDC3B KL TRPC3 MMRN1 CCDC88A SEC22C CALCRL BMPR2 PLEKHA1 TSHZ1 EOGT CBL ZBTB2 MOB1B ACER3 SPCS3 TMX4 ZEB2 DNAJB14 ARHGAP29 RBM7 STARD4 DNAJC18 HECW2 LIFR RAP1A PPP1R15B ZDHHC2 MAP3K8 RNF144B CNTD1 FZD4 ABCG1 HIPK3 PAQR3 CAMTA1 PAG1 SLC7A11 EIF4E PPP3CA SRSF2 SPTBN1 KANK2 TFEC ZEB1 EPM2AIP1 HNRNPU PDE4D TCF7L2 GPM6A MSR1 MTMR6 FOXO1 PPP6R3 PPM1K LIN7C RUNX1T1 REST HAUS2 PLEKHM3 ZADH2 THBS1 NPR3 PDE8A MGAT4A UBE2E2 SHC4 USP44 CXXC4 ELK3 PEAK1 KIAA0408 PAFAH1B1 PRDM5 PDE1C IKZF5 EFR3A CNOT6L MAPRE2 LIN7A ACTR2 FAM102B LIN54 RBPJ PPIL4 CREBRF SLC8A1 ID4 FLT1 METAP1 SYNPO2 PKNOX1 DDHD1 PHACTR2 NEK7 APPL1 CNTN3 UTRN HECA GABPA NXPE3 TBC1D12 FERMT2 SP3 PIK3R1 PRKCE CREB1 KBTBD8 RC3H1 ZBTB24 SH2D4B MSANTD2 RBM22 TRAK2 TCP1 TNFRSF9 OGFRL1 NAA30 CGGBP1 EPC2 LETM2 CYP4A22 CELF2 GAS2L3 AGFG1 CDK17 PKD2 SLC35F1 MAPK8 PKIA KLRC2 NAA16 BTBD7 ZFAND6 EPHA3 SORT1 PPP2CB GOLGA8R PBRM1 STRN PHF3 NR2C1 NDUFA5 ZBTB1 DCK PDS5B BAZ2B RSBN1L PDE12 GOLGA8H NAB1 C16orf72 MAP3K2 GNB4 ANKRD12 GNA13 GPR18 LTBP1 ATAD2B INO80D RNF2 GEM ANKLE2 LDLRAD4 INTS6 MIER1 FKBP1A CTTNBP2NL CEP170 MGAT2 SRP72 CDC42EP3 LRP12 TTLL7 UBE2D1 BRWD1 SSH2 GRIN3A SRSF10 KPNA4 RBMS3 LYSMD3 BCAT1 RASSF8 SCAI PAK2 SNAP29 FAM126B PRKG1 CAMSAP2 SAMSN1 C21orf91 RORA THEMIS2 SFPQ SLC44A5 ANO6 EVI5 TRIM36 ZBTB44 ZNF326 KALRN ACVR1C PLAG1 C5AR2 EXPH5 SVIL ZNF385B ZNF800 ENDOD1 HIPK1 SSB CLOCK OSGIN2 RB1CC1 HP1BP3 DYNC1I2 KBTBD11 ZBTB7C PLXDC2 FAR1 PIGK CTDSPL2 PRTG VPS36 SPTY2D1 PIAS2 WNT5A SGIP1 PCDH15 ARHGEF12 FNDC3A FAM218A MAP3K1 B3GALNT2 WWTR1 CNTN1 WDR26 TRIM25 RNGTT ORC4 CLVS1 GUF1 CEP68 EDIL3 GNPDA2 CFLAR CCNC IMPACT AKAP13 METRNL NFYB GPATCH2L SREK1 ERLIN2 KLRC1 ENPEP ANKH CBFB UBE2D2 CBLL1 ZBTB6 PLXNC1 YAP1	down	**
RYTTCCTG_ETS2_B	0.0001541	0.0044218	0.5188481	-0.2060342	-1.306469	925	GPD1 GPATCH11 CLEC1B SLPI TMEM100 NOVA2 SOSTDC1 CD101 PDLIM2 DLC1 HHEX KCNA2 ROBO4 RBMS2 GAPT USHBP1 GPR65 ADCY4 MIR22HG RAMP2 BMP2 CDH5 BDNF LYL1 ARHGEF15 MMRN1 HCAR2 TMOD3 CTSW CCDC88A LDB2 CITED2 FOSL1 CALCRL ESAM PLEKHA1 CLEC10A ARL8B STX11 MARCO NEDD9 NCF2 IL1RN TGFBR2 TRIB1 IL23A FGR ZEB2 ERG SH2B3 CD5 HBEGF RILP CHMP1B PLXNA2 CLEC7A TMEM204 CLEC14A PICALM NLK FOXP1 ZNF410 MS4A1 LCP1 DES GATA3 MED26 CD93 CRK TFEC SRGN ARHGEF2 SPI1 PDE4D MYCT1 FBXL5 EXOSC9 IL10 CSRNP1 PTGIR MOAP1 SPNS3 CASKIN2 MEFV NOSTRIN LIN7C TCP11L2 ID3 KLF9 VASP DENND3 CLDN5 GRK5 MPL SSH1 ATL3 MGAT4A NFKB1 CDKN1A ST7L PTPRC M6PR XCL2 UBE2B PRF1 FCER1G PER1 ELK3 ELMSAN1 PPP2R5C SH2D2A VAMP5 PRICKLE2 ZNF706 IL7R PAFAH1B1 CALM2 MIR17HG AFF1 IL24 TLL1 CMTM6 CNRIP1 PTH1R ARHGDIB ACTR2 FOXN3 MYLIP RBPJ MYO1C ARL6IP5 ETF1 S1PR4 HCAR3 CNTF FLT1 CREM SGK1 CTSS AQP3 HCST STAT4 ZFP91 NSMCE2 ETS1 MAP4K4 CNTN4 TYROBP ELP5 JUNB RHOJ DHX15 IPO7 SP3 PIK3R1 GPR183 CDK2AP2 STX5 GRIA1 MSANTD2 TPP2 CAP1 PRKACA SNX22 RALB TAGLN2 EPC2 WDFY4 FGFR4 ESPNL TNFSF13 HIVEP2 RBKS RUNX3 FOXO3 TREX1 KLRC2 RIN2 CCR4 STRN DCK TGIF1 CD6 SBF2 CD86 ATXN1 CCR1 GPR18 VPS39 ZNF296 ADAM10 TMA7 PRICKLE4 MBNL1 GTF2B CCL20 AMD1 RNF138 IL18RAP LAT ARPC2 ZNF143 EGFL7 ADAMTS4 SF1 VGF ELOVL1 NT5C2 ARRB2 SPIB PIP4K2A TAB2 DIXDC1 ACTB SLC2A9 HNRNPK EPHA2 SSH2 OSER1 CD19 STK4 ZDHHC5 PTEN LTBP3 RORA FAM13C TOMM5 DOCK4 TRAPPC11 GRB10 EMC3 PUM1 CNN2	down	**
MIR4262	0.0003717	0.0084038	0.4984931	-0.2128978	-1.305742	641	TRIM71 IL1A SGK3 ATXN3 ADCY9 MBOAT2 RAB3C OTUD1 SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 TET2 OTUD4 EPB41L3 ZBTB2 TGFBR2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B NAAA PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 TMEM123 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 TFRC ADARB1 AGO4 PER3 ADO SLC38A11 ZADH2 GAPVD1 NR1D2 TADA2B CD302 RECK ZBTB43 UBE2B ELMSAN1 DSE CUL5 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 TLL1 CDKN2AIP PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF METAP1 CDC40 PHTF2 COPS2 NEK7 PLEKHA3 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 FRYL CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 LRRC32 IRS2 ZNF136 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL NPAT PKNOX2 LIMCH1 CUL3 RASSF8 TIMP3 FNIP2 CHCHD7 CECR2 FAM126B KIF1B CAMSAP2 RORA CNTNAP3B DOCK4 GRB10 PUM1 PURB MIER3 DMXL2 CBX7 SETX KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 ADAMTSL1 ENDOD1 HIPK1 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1 SPTY2D1 GOLGA8B PAX5 ZNF14 TSC22D2 RAD21 POLI	down	**
ELF2_TARGET_GENES	0.0030416	0.0352432	0.4317077	0.2592448	1.305462	694	RUVBL1 CEP89 COIL NUDCD3 PHF14 SRGAP3 TBRG4 THEM4 METTL1 GTSE1 KIF14 SNF8 STIL FLAD1 COPB2 GON4L MCM8 RCCD1 NCAPD2 SMUG1 ZNF107 UQCC1 LSM5 GOLPH3L RAB11B-AS1 RPAP1 COPG1 WASF1 FBXW9 TIGD4 EXOC4 RPL32P3 CCT5 CENPL EME1 NUP155 NDUFS2 ZNF587B ODF2 SMARCAL1 COASY CDNF HELB SETDB1 KLHDC4 MRPL27 PHKG2 KIF11 MCM3 AP1M2 POLR3C CCDC148 RAD51AP1 SPATA17 FDXR ARL16 HSPBP1 TFCP2 DDX56 INCENP ZCRB1 RASSF6 TERC CDKN2C KIAA0556 ANAPC5 ING4 RNPC3 CDK12 WDR5B SSBP1 CCDC61 RFWD3 AP3D1 PICK1 KIAA0753 ZSCAN25 AAGAB TYW1 POC5 AP5Z1 RNF181 NUP205 TTI1 TTC16 WDR24 ZKSCAN5 UNC45A CHCHD2 PARS2 TELO2 C19orf44 SEC16B SPG7 PSMA5 MAN1B1 LONP1 CENPQ MLEC CSNK1G1 OS9 FZR1 PKP4 ACAD10 CLTA LIN37 TMEM186 GFM2 C15orf41 IQCH SND1 SIL1 C12orf73 ZBTB45 ELAC2 ATP13A1 CNDP2 ARHGAP12 BAZ2A SH2B1 TMEM234 ACBD5 GTF3C1 PPHLN1 VPS25 RPRD1B WDR34 RIN1 FAF1 MRPS23 UBXN6 PPP6R1 GMPPA NOL6 MCM6 STAMBP WDR83 RPL7L1 CD2BP2 MALSU1 EIF3D SLC35A3 SCYL3 LRCH4 AATF PRSS16 KATNB1 MRPL51 SMARCC2 STK35 GOSR2 U2AF2 CEP152 ZSCAN16 DUS2 GTPBP10 ZNF580 ZNF837 ZNF622 B9D1 RBM42 ZNF169 GTF3C2 RNF121 WDR4 CEP164 CAPN10 ZNF384 TRIP4 PFKM COPA ZNF217 UBAP2L TMEM260 XPC POLR1A DNAJC14 ZMAT2 TRUB1 HGS FIS1 TMEM9B-AS1 SIGMAR1 SF3B2 ENO1 TMEM38A TPRN COX17 ALPK1 MZF1 FTSJ3 TRAPPC6A ANKRD11 SLC33A1 COPE INO80B SLC38A10 MBTD1 DGUOK SPHK2 CXorf40A SH3RF2 UTP18 GSK3A EIF2B1 CDK11B CRB3 PNPO DEPDC5 LCMT1 ZNF688 TNPO3 GGA1 OPA1 AP2B1 NSL1 TOMM40 ZNF774 TIMM10	up	*
MIR519C_3P	0.0041053	0.0429325	0.4070179	-0.2260189	-1.304194	348	EREG SFRP4 DPYSL2 TMEM170B HSD17B11 CCDC88A CRY2 BMPR2 RXFP1 TGFBR2 MOB1B HPS5 CIT TEX2 HEG1 ARHGAP29 ZBTB4 RAPGEF4 LATS2 PPP1R15B MAP3K8 SLAIN2 FOXJ3 ANKRD29 BTG3 CYP4V2 TIPARP FBXL5 LRP4 TAPT1 ROCK2 PRDM16 CDADC1 STK17B SNIP1 SSH1 PDE3B NKIRAS1 UXS1 ELK3 ADIPOR2 PAFAH1B1 NCKAP5 EFR3A KREMEN1 TOPORS CREBRF PHTF2 KIF13A PIKFYVE HECA ZFP91 UHRF2 JAK1 BAG5 ATXN1L CREB1 KBTBD8 RAB8A MAPK4 ENTPD4 ZNRF3 NAA30 PXK SNRK HIVEP2 PKD2 BTBD7 PIK3AP1 CPA3 TESK2 ZFYVE9 YTHDF2 CDC37L1 SKIDA1 CNOT7 MAP3K2 HBP1 MYOCD HFM1 STX12 MBNL1 PRDM8 PITPNA ARAP2 INTS6 ABL2 ITPRIPL2 RTN1 TMOD2 EPHA4 HSPA8 BRWD1 CUL3 DNAJB9 FAM126B CAMSAP2 ITCH LDLR NRP2 GRB10 NABP1 WDFY3 SPOPL MIER3 MAN1C1 EIF4G2 IRF2	down	*
MIR561_3P	0.0018331	0.0248702	0.4550599	-0.2253911	-1.301480	410	TBX3 ZC3H12C CPEB2 ATXN3 CLDND1 SH2D3C PTPMT1 RASAL2 BAIAP2 QKI YPEL5 ARL8B PRKAR1A VAPA TET2 CIT PDCL PPM1N ZEB2 ARHGAP29 UBR3 SLC36A4 FAM124A C1orf21 PBX3 ZNF503 SPIRE1 ZBTB21 PRSS12 PEX5L ZBTB8A HERC3 ZYG11B ROCK2 MTMR6 PTPN21 SORBS1 CASP1 SETD9 PRKD3 ID3 TJP1 FBXL3 SPAG9 NR1D2 CCL4 USP44 PTGER3 ZBTB43 SLC6A6 SPRYD7 CRIM1 CNOT6L ACTR2 ZDHHC20 PRKRA VPS37A PHTF2 DDHD1 EBF2 NEK7 RNF141 MAML2 PPA2 CPEB4 FERMT2 FYTTD1 IFRD1 PNPLA8 HSPA13 MBNL2 CREB1 RC3H1 FAM177A1 CGGBP1 CDK14 AGFG1 MBP PKD2 CCDC85A MYL12A BTBD7 ZFAND6 PPP2CB KIAA0232 ZBTB1 TEX14 ABHD13 IRS2 C16orf72 PCDH17 N4BP2L2 MICU3 ADAM10 CLEC2B MR1 ARPP19 CCNH PRDM8 INO80D SFT2D1 NBN ACAP2 LRP12 SEC61B ARIH1 ZNF471 KPNA4 CUL3 CCDC92 PAK2 RORA ZFPM2 WDFY3 NUP160 SLC35A1 ZBTB44 SNRPG	down	*
ZNF134_TARGET_GENES	0.0016795	0.0232939	0.4550599	0.2561503	1.301320	823	CEACAM1 PTGES MEGF10 HOXB-AS3 CEP89 DNAH2 MCM10 EPN3 CHEK2 C1RL-AS1 B4GALNT4 NEK2 DROSHA FBXO27 WFDC2 PDCD2L CYP2J2 TTF2 SLC25A21 ZNF138 METTL1 ZFHX2 CDK4 C4orf50 ZNF285 FLAD1 SEC14L5 ACAD9 ZNF714 STC2 GOLGB1 KCNT1 SMPDL3A SPINT2 ARHGAP33 GRHL3 FBXL19-AS1 PDE9A ZFP64 MYL6B NUB1 KAZALD1 WDR62 C5orf34 STRA6 DYRK1B ZNF391 BBS1 STAP2 TP53BP1 CCDC77 LGMN EXOC4 TMEM184A HOMER3 EME1 SPTB HHAT POLA2 GTPBP3 IRF3 MCM7 C1RL RGL1 ADAMTS13 CCDC114 ZNF146 DCDC2 MRPL27 BLOC1S1 SEC61A1 SARS2 POLR3C SCAMP5 NFYA KIF3C THAP10 IPO9 FBXL19 BLM PHB C2CD3 ALDOA NRG4 SPRY1 R3HDM2 OSBPL7 PARP1 ZNF229 FGGY APLP1 ANAPC5 SSBP1 PACS1 PHF12 GOT2 ACP6 ZNF541 SLC16A13 TRIM2 PSMB5 STAT2 DNA2 SEC61G PMEL ZNF584 FAM186A CCDC88C LINC00649 OARD1 NAPEPLD CCDC57 CBFA2T2 C9orf43 STK11 ANXA2R ZNF500 GAL3ST4 CATSPERG ILF2 TAPBP DLGAP5 PDCD11 NDUFA11 ZNF233 CNOT2 PSMA5 ALDH7A1 ZNF133 SNRPA DHRS4-AS1 MC1R OSBPL3 KIF22 ROGDI ARHGAP5-AS1 ZNF761 ATG9B GINS2 HIP1R MTND5P11 TJAP1 AGPAT5 SPAG1 KIF20B LIN37 SRD5A3 OTX1 ENOSF1 TMEM186 TM9SF4 NTN3 BCL2L12 S100A13 FAM200A PRRG2 PPME1 NT5M DNASE1 PPIEL MDGA1 LIMA1 LINC00910 UBE2O PPHLN1 TUBG2 FTCD ASB6 ZNF428 ZNF616 TCTN1 UBXN6 CDR2 KRT8 KDM4B ZNF160 PPCDC RAI14 NSUN6 NOSIP HHLA3 ANKS3 HEATR1 C5orf22 NFE2 PRSS16 CREB3L2 TTLL6 CCNG1 PHC2 SMARCC2 TCHP U2AF2 TPM3P9 PRPF18 DZIP3 RTEL1 ANAPC2 DOHH CCDC167 PAK4 STAT6 ZNF436 VPS33B PRSS22 ARRDC1 BMP8B ZNF292 ARHGAP5 COPA TEPP SRP9 MRPL21 KIAA0825 LINC00240 AGBL5 HOXB2 TMEM101 PTPRF SNORA14B NUBPL TBCB MXD3 SNUPN ALKBH6 ZNF131 OSGEP POLR1B TARBP2 SYNRG MAPK8IP3 SRCAP E4F1 MPG FZD3 POP4 NPTX1	up	*
MIR548AW	0.0013611	0.0206431	0.4550599	-0.2178826	-1.301215	493	PRMT8 EPAS1 GCOM1 SECISBP2L RBMS2 CLEC3B NUP54 LRRFIP1 INSIG1 GPC5 TMEM170B OTUD1 QKI BMPR2 S1PR1 MEF2A CDC42 NEDD9 VAPA EOGT USP47 CCNL1 ZEB2 STARD4 HECW2 RAP1A PPP1R15B MTF1 PLXNA2 PBX3 HIPK3 GLS MALL PEX5L SLAIN2 PLXNA4 AKT3 ITSN2 PDE4D UBE2D3 TFRC ATP6V1B2 FBXO8 AGO4 PRDM16 AHNAK SORBS1 BNIP2 KLF4 TMED5 KLF7 UBQLN1 SNIP1 RBMS1 GPR85 EPS15 WASF3 CLIP4 FAM76B NCKAP5 AKIRIN1 TLL1 CNOT6L ZDHHC20 FOXN3 TMEM9B SPIN1 CREBRF DCP1A PDIK1L PHTF2 SGK1 HCFC2 PDCD6IP PPP6C C20orf194 PDE5A BMP3 UHRF2 PIK3R1 FRYL FAM43A KBTBD8 NUDT15 HOMER1 CASZ1 CGGBP1 RHOQ PPTC7 MAPK8 TSHZ3 XYLT1 CR1 BTBD7 ING3 SPOP PBRM1 DDHD2 STRN NR2C1 DCK DPM1 VAMP4 CNOT7 HFM1 GNA13 PLAA ARPP19 INO80D HELZ PITPNA GEM MIER1 MGAT2 ACAP2 BRWD1 HNRNPK POLR2M ZDHHC21 GRIN3A KPNA4 PALD1 TBCEL FNBP4 LIMCH1 FOXJ2 PTEN B3GNT2 TMCC3 LDLR NR3C2 FAM13B GSPT1 WDFY3 PUM1 SPOPL ELFN1 PURB SMAD4 RBMXL1 MB21D2 CFL2 CHIC2 CLIP1 ENDOD1 HIPK1 ATF2 LHFPL2 CLOCK MAMDC2 CCNK KMT2E CBR4 PTGS1 CTDSPL2 EBF1 SV2B VPS36 API5 SPTY2D1 LDB3 SCAF11 MAN1A1 TES ADH1B RNF111 CNTN1 PDPN ROBO2 SREK1IP1 NEXN FNIP1 CCNC MAT2B	down	*
MIR651_3P	0.0002124	0.0056599	0.5188481	-0.2138378	-1.301210	674	WEE1 RTKN2 SEMA6A COL25A1 SOSTDC1 USP12 GPIHBP1 ZC3H12C LRRC8C ATXN3 PRKG2 ADCY9 PTP4A2 EMP2 KCTD9 PTPRB TMEM170B CAV1 CORO1C QKI TMEM138 BMPR2 TBXA2R KCNN3 IL1RN C3orf70 OTUD4 CBL TMX4 ZEB2 UBL3 LATS2 SDE2 PICALM NLK REV3L FOXP1 HIPK3 PAQR3 KLF6 GLS CAMTA1 SLC7A11 GPBP1L1 SERPINB9 FAM122A TRAF6 AKT3 TMEM41B EPM2AIP1 ZYG11B FBXO8 FBXL5 SLC7A2 TAPT1 AMOTL1 FOXO1 SORBS1 AFAP1L1 RUNX1T1 RRM2B ANKRD10 BCHE KLF7 FBXL3 SPAG9 MGAT4A CADM1 HNRNPUL2 PAPSS1 UBE2B PIK3C2A CPT1A N4BP2L1 DSE TBX5 SLC6A6 N4BP1 KIAA0408 PDE1C AFF1 NCKAP5 IKZF5 CMTM6 EFR3A CNOT6L ACTR2 PIAS1 STK24 HGSNAT LIN54 FOXN3 ZNF426 LACC1 RBPJ DCP1A DDX60L RYBP PHTF2 RNF141 RAB8B SRSF3 ETV3 MITF HMBOX1 SLC14A1 ZFP91 CELF1 MN1 DDX17 MAP4K4 CNTN4 FBXO11 ATXN1L ENPP4 EEA1 GLIPR1 HSPA13 PRKCE IDS RC3H1 FSD1L LPCAT2 TRAK2 CXCL5 PREX2 NAA30 ZNF407 POGLUT1 SLC25A24 SPRY4 PELI1 CD164 PTP4A1 AZI2 USP7 ATG3 PBRM1 HNRNPA2B1 NR2C1 ZBTB1 BAZ2B HECW1 MTMR2 ATP6V1A GALC MAP3K2 PPP3R1 APLP2 TAGAP NPTN RIMKLB ARPP19 INO80D RNF2 C3orf38 INTS6 SF1 ALDH1B1 CDC42EP3 TAB2 ARIH1 ITGAE ALDH6A1 IPO5 FBXO25 BRWD1 ZDHHC21 SSH2 SOAT1 NHLRC3 CUL3 BCAT1 TTC28 EDN1 NALCN RNF38 SCAI PTEN FAM126B SYNPO2L RORA ITCH NRP2 NABP1 MAPKAP1 EHD4	down	**
DBP_TARGET_GENES	0.0004405	0.0095545	0.4984931	0.2523752	1.295708	1215	ATP10B TSPAN8 TRIP13 HS3ST1 SPATA24 C1GALT1 DDX12P HJURP FAM81A PKP2 CDC45 TICRR PARPBP RPGRIP1L CHEK2 S100A2 BUB1B NUP107 XYLB ZNF12 DROSHA TIMELESS HOXB6 COA1 PSPH GGCT CHCHD6 BET1 MRPL46 CDK4 SMPD3 RACGAP1 HILPDA NABP2 EIF2B5 AP1S1 TTC26 SAP30L-AS1 NUF2 CCNB2 BCL2L14 PRC1 EIF3B CCT6A PIP4K2C KIAA0895 ZNF3 CAND1 NCAPD2 DZANK1 INTS1 LSM5 FAM220A NME1 BTRC RAB11B-AS1 SMARCC1 ZNF391 KIF23 BOD1 KNTC1 RHNO1 TSGA10 TIGD4 EEF1E1 RPL32P3 TMEM184A AURKA NUP155 CBX3 NDUFS2 SAE1 RAB19 IRF3 KIF2C MAD1L1 MPHOSPH9 CPD SPEF2 RBM28 NSUN2 MORN1 ERAL1 ZNF146 LINC00511 SEC61A1 TARS2 SP140L RNFT2 LETMD1 WDR60 BRD9 SARS2 LINC00265 CHEK1 SCAMP5 AHCY RAD51AP1 TIMM50 MRPS11 BLM MRPS30 PHB SYMPK FBXO16 ALDOA DET1 STXBP4 TULP3 CCDC138 LEF1-AS1 CNPY2 PPP1R37 RECQL5 CAPN8 MEA1 PPIL2 NUSAP1 TMEM106C SUPT5H CBX5 ANAPC5 ING4 HDGF CDK12 WDR5B CEP97 LMCD1-AS1 KCTD7 MDH1B PICK1 EEPD1 C1orf112 PHF12 ATIC NPM3 ACP6 VPS28 SMG9 STEAP1 ZNF815P PSMB5 STAT2 PRR14L ANAPC7 NUP205 TMEM79 POC1B LINC00649 MRPS12 METTL3 RNF207 TTI1 TNRC18 UQCC2 NOP2 ZKSCAN5 SRD5A1 PA2G4 LZTR1 UBN2 CHCHD3 TPD52L2 RNF44 ACBD6 ZSCAN21 TSPAN17 EXOC7 VIPAS39 C19orf44 SMG5 WDR53 NDUFA11 SEC16B TAPBPL SPG7 COA3 VPS41 GALK2 TSNAXIP1 JOSD2 NMRAL1 SNRPA MNS1 AARSD1 MAN1B1 RAD9A LONP1 CCDC151 OSBPL3 KIF22 ZMAT5 TRIM37 COX7C MORN2 COPS7B FBXO4 PPOX PLEKHA8 AKAP8L MEGF8 TP53TG1 CCDC146 MRPL4 VIL1 ITFG2 CLTA TMEM186 ASNS GSTK1 SLC4A2 BCL2L12 CD27-AS1 C15orf41 CKMT2-AS1 SIL1 ENC1 AAMP YARS2 NIF3L1 SLX4IP RAD50 NR6A1 KDM3A CENPK BAZ2A CHPF SASS6 GEMIN6 KLHDC3 SH2B1 TADA3 LIMA1 L3MBTL2 DGKA RPRD1B WDR34 AAAS GBF1 BCL2L1 GMPPA PELO SRRT CDK5RAP2 KRT8 MYPOP MRPS33 ANKIB1 METTL2B RPL7L1 UBL7-AS1 MED24 TMEM147 USP21 NMNAT1 CD2BP2 SPINK5 TMEM198 LSM7 C5orf22 EIF3D SRSF1 HAX1 C1orf109 LRCH4 KATNB1 MRPL51 ETV6 WDR27 AP4B1 SH3BP5L SF3A2 DDX55 SPSB3 GTPBP10 KLHL7 FARSA CEP85 ZNF622 NME1-NME2 AMN1 RER1 MCRS1 RPS26 MAP3K14 PRDM10 ECH1 TXNL4B DOHH PCBD2 CTU1 STAT6 ABCF2 WDR4 NUBP2 TTC1 STK25 TRIP4 ZWILCH TOMM40L PPFIA3 PFKM SAMD4B TYSND1 ZSCAN22 GBP2 SNRNP200 RPRD2 CDK5 SNX8 TMEM101 FAM83E MXD3 AURKAIP1 VDAC3 ALDH3A1 C1orf159 DNAJC14 SRCAP POP4 ZMAT2 LRSAM1 FIS1 LEMD2 SLC36A1 EPHB4 FBXO45 BCAT2 NELFA SFXN5 MRPL20 SART1 ATF7IP CCDC91 NAT10 MUC1 C4orf46 TRUB2 ILVBL FAM222B SCAF1 ATG4B CALU SART3 HEMK1 FTSJ3 C12orf10 FBXL18 ANKRD11 ALKBH2 CSTF1 TPM1 INO80B CEP290 METTL18 HEXIM2 NUMBL PLAC8 DHX57 MORN4 TNFRSF1A SETD1A WDR55 SLC38A10 MUS81	up	**
GRHL1_TARGET_GENES	0.0004585	0.0098627	0.4984931	0.2519265	1.295144	1271	ATP10B SYT8 MUC13 IGSF9 PKP2 CDC45 BDH1 EPN3 NGEF RBBP8NL ZMYND8 NUP107 NEK2 COIL CENPF COA1 SEMA4B PSPH GGCT KIF18B TTC25 PHF14 TSFM CREB3L4 ZNF138 TUBB2B TMC1 C6orf141 RACGAP1 UBE2Z NOL12 NAALADL2 EIF2B5 SEC14L5 NUF2 CDCA8 AURKB ECT2 RBBP8 XPNPEP1 PMS2 APOL2 TMCC1-AS1 CIB1 TMCC1 COPB2 CCT6A KIAA0895 PDE9A RCCD1 DZANK1 MYL6B CDK5RAP3 SPDL1 UQCC1 NUB1 KAZALD1 FAM220A SYT12 NME1 WDR62 MIR4458HG BZW2 EXO1 RAB11B-AS1 STAP2 RNF216P1 KNTC1 CLHC1 EXOC4 RPL32P3 CENPL EME1 IQCD WDR3 NDUFS2 MYO10 C1orf226 SAE1 SFI1 E2F2 CENPW WDR78 COASY TPCN1 MMS22L RNF43 AKAP1 SETDB1 RAD54L ERAL1 PKM MRPL27 ANKMY1 MCM3 ZNF226 LINC00511 MCCC2 AIMP2 TARS2 L3HYPDH SLC2A11 RNFT2 PSMG4 OAZ3 SIDT1 PEX26 MAD2L1 NFYA DCTPP1 MDM2 SPC24 AKT2 SPATA17 EHF C6orf223 DDR1 FDXR FBXL19 PHB DET1 NIPAL1 PARD3 SRRM5 TULP3 CNPY2 MYO1A RECQL5 ZCRB1 RNF216 CDKN2C PPIL2 SUPT5H ING4 WDR5B MCTP2 EXOSC2 CCT3 ABHD17C C1orf112 PHF12 TNK2 RBCK1 POC5 ITGB8 VPS28 SLC16A13 TRIM2 ZNF815P PSMB5 STAT2 GJB3 SEC61G PMEL RNF181 SDCBP2 PSAT1 ANKRD26 ANAPC7 EGF LINC00649 THAP8 OARD1 TTI1 ETFB LCA5 MYO5B AK7 MTBP SNRPE GOLGA5 NLN NOP2 PSMC4 CASC1 ZKSCAN5 C9orf43 PA2G4 UBN2 ZNF692 RANGAP1 PYROXD2 POLR2H ACBD6 CCDC142 ATP7B DCAKD NEK10 SEC16B VPS41 CNOT2 PSMA5 ALDH7A1 MLF2 UROS ARHGAP32 CCDC151 PLEKHG3 PIGG GPRC5C MRPL11 USB1 MORN2 DPH2 KCNC3 TMTC2 RHBDD3 SOX2-OT CCDC146 IQCK ANP32E RNF224 ACAD10 ZSWIM1 TMEM186 CCDC51 KRT19 C15orf41 IQCH THRB LTBR FAM200A CEP128 CCDC159 ATAD5 ATP13A1 IP6K2 ARHGAP12 GEMIN6 EFCAB7 GTF3C1 LIMA1 PPHLN1 L3MBTL2 DGKA RPRD1B CENPM ANKRD6 ERBB3 MAN2A1 EFHC1 FAF1 POP7 ASCC1 ACLY PPP1R3D CHMP4C ABCC3 CDK5RAP2 KRT8 ODF2L MGME1 ZNF160 BLCAP MRPS33 ANKIB1 METTL2B ZNF446 WDR83 RPL7L1 DHX8 NOSIP CD2BP2 MRPL53 SLC35A3 SCYL3 HAX1 C1orf109 FBXO36 URB1 SNX11 NEURL4 DUS4L OVOL2 SLC1A5 RPP38 SMARCC2 ANK3 ALG8 CEP85 SUV39H2 NME1-NME2 PMS1 ZNF224 RPS26 RRNAD1 NCDN ULK4 HDLBP CISD3 BANF1 POLR3B RNF121 PAK4 TTC31 CCDC9 PRPF31 ARRDC1 BMS1 FARSB ZNF384 TRIP4 ZWILCH FBXW11 PFKM KCTD21-AS1 SCOC ZNF700 NLGN2 MRPL9 TYSND1 TRAK1 KIAA0825 NME7 LINC00240 AGBL5 TMEM101 MXD3 AURKAIP1 SNUPN VDAC3 UQCRQ ZNF131 BCL6 GOSR1 ANKMY2 CLNK CGN CELSR3 FRMD6 RAB25 NMT1 GDPGP1 NEIL1 PAICS TMEM256 ZNF526 MRPS27 TBL3 PNN TTC9C KRT80 FAM185A ULBP3 SART1 TMEM38A RAD1 MRPL48 NDUFB7 RRS1 NLGN1 STK11IP C4orf46 CLASP1 FAM222B THRB-AS1 MOK SART3 HEMK1 BRIX1 ZNF33A C12orf10 MSANTD4 ZNF629 RPUSD3 CLNS1A TTC5 TFB1M FAM47E TOMM7 ZSWIM5 TMEM62 EIF2D METTL18 DHX57 EID2 ZNF319 SETD1A ZDHHC1 RNF126 BMF DEPDC4 MRPS16 ACSM3 EGOT TOP3A ITGB5 KLHL42	up	**
MIR519D_3P	0.0014115	0.0211498	0.4550599	-0.2157764	-1.294346	528	RAB11FIP1 EREG TMEM100 ABHD5 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	*
MIR3658	0.0002729	0.0067985	0.4984931	-0.2116172	-1.293126	666	RTKN2 TMEM100 SC5D COL25A1 SASH1 ABHD5 SLC12A6 GPR15 CD55 ATXN3 SNX10 NUP54 GPR65 MBOAT2 RAB3C INSIG1 GPC5 TMEM170B KLHL8 RASAL2 LONRF1 QKI BMPR2 IDI1 PRKAR1A TET2 CBL SLC11A1 ZBTB2 MOB1B TEX2 HEG1 ZEB2 ZBTB4 KIAA0355 WWC2 ATP2B1 DNAJC3 SLC36A4 SLC25A17 SBDS PCYOX1 PPP1R15B CHMP1B SDE2 C1orf21 ABCG2 MASP1 RNF144B LITAF ZBTB21 HIPK3 DACH1 SLAIN2 PPP3CA RB1 SLC25A37 TFEC EPM2AIP1 BTG3 AMOTL1 FOXO1 SCP2 LIN7C PEG3 RUNX1T1 PRKD3 UHRF1BP1L ZADH2 TMED5 FBXL3 SPAG9 MGAT4A CADM1 GPR85 CYP20A1 USP44 PTGER3 ZMPSTE24 GCA CLIP4 SPRYD7 PDE1C CNOT6L CDKN2AIP CNRIP1 FOXN3 RAB6A SERTAD2 MYLIP PDIK1L LRRTM2 PHACTR2 PLEKHA3 HCFC2 ARL5B GABPA ZFP91 ETS1 ADRA1A BMP3 FOXN2 IPO7 EEA1 PNPLA8 LYRM1 GPR183 MAPK4 ZNF555 GRIA1 NAA30 ZNF407 WDR7 CELF2 CDK14 PLCG2 AGFG1 SNX9 SLC25A24 RHOQ AGPS NECAB1 HIVEP2 KLRC2 NAP1L5 BTBD7 HNRNPD NUP153 ZBTB1 DCK ZCCHC10 KHDRBS1 MCUR1 MAP3K2 CSDE1 GNB4 PPIG CRY1 MICU3 PGGT1B ABI3BP GEM BNIP3L INTS6 INO80 EPB41L5 ZNF438 PUS10 SEC63 BLOC1S2 B3GALNT1 CYB5R4 FBXO30 TOB2 RBM18 UBE2D1 NUP98 SOAT1 LYSMD3 FDX1 TTC28 RAB2B GTF2F2 RNF38 SCAI PTEN B3GNT2 KIF1B TMCC3 FAM13C LDLR NABP1 MAPKAP1 DUT PURB ARFGAP3 ZBTB44 PAPSS2 PPP1CB RABGEF1 HAT1 YTHDC1 MB21D2 GHR CLOCK MZT1 SH3GLB1 FAM8A1 TBC1D23 PLXDC2 CCNT2 ADAMTSL3 PIK3CG COX20 DNAJB4 PRTG CEP44 LMO7 WDR41 CCDC93 PAX5 WDR47 HMGB1 MAN1A1 IL5 PAXBP1 CUL2 PYROXD1 DR1	down	**
MIR23A_3P_MIR23B_3P	0.0016938	0.0234056	0.4550599	-0.2159220	-1.291495	489	WEE1 EPAS1 TRHDE SOWAHC ZC3H12C CPEB2 PTPRB TTC7B RCOR1 ZBTB34 MED4 KIAA1109 NEDD4L CALCRL ZCCHC2 ELF2 INPP5A ARL8B MEF2A RXFP1 WBP4 LAMP1 AGPAT4 ZBTB2 TGFBR2 TRIB1 C12orf76 SEMA6D RAP1A MTF1 SWT1 ECHDC1 SERINC1 NLK GLS CAMTA1 ZEB1 MYCT1 TMEM38B SCP2 CLEC1A BNIP2 PPM1K TJP1 TMED5 GRK5 CDS2 PNRC1 ZBTB43 N4BP1 VEPH1 NUS1 CNOT6L VCPKMT NCOA1 C2orf69 LIN54 TMOD1 CDC40 PKNOX1 NEK7 MAML2 RAB8B PRPH2 SEC14L1 DDX47 MITF PNMA2 CARD8 MAP4K4 TBC1D12 PTGER4 DHX15 SDHD PRKCE GTDC1 DENND4A CGGBP1 CELF2 GAS2L3 CDK17 FOSB PKIA NAA16 NAP1L5 STRN NDUFA5 TGIF1 TEX30 CBFA2T3 ATXN1 MEIS1 WBP2 STX12 MICU3 ZNF267 PDE4B CCNH BNIP3L FGF2 INTS6 RPP30 SFT2D1 ORMDL1 TMOD2 UBE2D1 IPO5 FBXO25 MEX3C BRWD1 G3BP2 SSH2 KPNA4 STK4 CUL3 JMJD1C RNF38 PAK2 PTEN FAM126B CAMSAP2 RORA MT2A TLK1 SPOPL CNN2 ZBTB44 SNRPG MAP4 REEP1	down	*
ZNF2_TARGET_GENES	0.0020450	0.0270566	0.4317077	0.2526944	1.290373	943	PPM1H STYK1 PTPRZ1 KIF20A GPR89A CPLX2 AK4 DNAH2 AP3B2 ABCA17P ADRA2A DOC2A PRTFDC1 C17orf75 PDCD2L STOX1 TSHZ2 TSFM SRGAP3 METTL1 GINS1 CDCA2 PCDHGA6 NOL12 SDHAP3 ANKRD24 TTC26 GRIN2A ZNF714 SPATS2 HOXB7 SPINT2 UMPS GON4L ZNF3 XPOT SMUG1 COQ3 AP1G2 CCT2 INTS1 SYT12 DNAI1 TOP3B PPP1R9A TTLL4 ARMC4 PLEKHG1 TMEM41A DNPH1 SMARCD3 MAP7 SMARCC1 FOXJ1 AP4M1 FRS2 DPY19L1 RFXANK EME1 SPTB GTPBP3 MCM7 ZNF860 IL12B MPHOSPH9 C14orf93 WIPI2 ANKRD52 RBM28 RNF157-AS1 ASPHD1 RNF43 FNDC5 AKAP1 WNT1 HOOK1 AMACR MRPL27 CMBL FANCD2 CDC25C TARS2 LETMD1 KCNJ11 FNTB SAMD10 KLHL3 SYMPK ALDOA R3HDM2 MARK1 TXLNB RNF216 CDKN2C SUPT5H C2orf50 SLC39A11 ZNF45 HDGF CDK12 LINGO1 DTD1 ZNF260 ANKRD54 GMNN NAV2 POC5 PGBD2 STEAP1 CCNJL GNPNAT1 SDCBP2 ENPP3 PEG10 KRBA1 CCDC88C TMEM79 MTBP ATAD3A RNF150 SNRPE ABCA4 ZNF827 PSMC4 ZNF623 CENPP PA2G4 IRF6 LZTR1 GIPC1 GOLGA3 SMG5 SPG7 AMPH EFCAB2 UROS C19orf12 KIF22 PIGG UBE3D ROGDI PPP1R26-AS1 TMTC2 HDAC1 URGCP MLEC IL15RA LMTK2 GEMIN5 MRPL4 LINC00662 ANP32E LRWD1 GSTK1 POLD1 FAM207A THRB FAM200A MAGOHB PRRG2 PEX10 ZBTB45 ZNF140 SLC1A3 RAB24 CABLES2 PCDHGB1 ETV4 PROX1 PFAS LSG1 BRD8 KCNB1 VPS25 AHCYL1 ERBB3 WDR34 AAAS FTCD SIRT4 KLHL32 EFHC1 C12orf65 DUS1L NRXN2 LRRC59 AP3M2 SLC6A1 ARHGAP22 PPCDC CELF4 LPCAT4 CENPT ZSWIM8 NOSIP CCSER1 CACNB3 SCYL3 GINS3 FBXO36 POLR2J3 KATNB1 IGHMBP2 RSPH4A PPP1R3E SMARCC2 DDX55 COPZ1 SPSB3 GTPBP10 GNAL NUP62 SPAG4 INTS8 PRPF18 MCRS1 ZNF212 RRNAD1 BBX BANF1 ARSA CDC42BPA DOHH DTNB STAT6 CDK5RAP1 CLUAP1 NUBP2 HOOK2 TRIP4 CHMP1A ARHGAP5 ZNF217 GTF3C5 SAMD4B MRPL21 LINC00240 TMEM101 TBCB AURKAIP1 ZNF131 SIRT6 ZNF91 TCF3 EIF4G1 SRCAP ADRM1 ADAM15 POP4 NPTX1 PDZD7 TRUB1 ZNF341 SLC36A1 TBL3 UBTF MRPL48 ZNF367 TRUB2 THRB-AS1 NELL2 C12orf10 KCTD19 SETD5 FBXL18 ANKRD13D NCAPH SLC33A1 SPATA33 BCKDK GLIPR1L1 INO80B EIF2D LASP1 ZNF511 MRTO4 ANO8 MED22 SCRN2 GLI3 MAN2C1 VPS16 PDK2 NR2F6 PTPRK TRAFD1 PARL TMEM259 RPL36 HDAC10 RBL1 APBA3 NFE2L1 USP35 RAB11FIP3 KIFAP3 NSL1 SLC4A1AP STARD10 TSC22D4 TEFM PRCC KCNK1 ABCD3 CNTNAP2 RAB26 MAP3K5 CS RAC3 GGA3 TIPIN BRD4 TTC13 CDH24 DTX4 TMEM219 RPL41 BNIP1 KMT2D KLHL17 SAP30L WDR25 SLC44A1 LRRC37B DPYSL3 ZNF30 PAWR CACNA1A PDXDC1 COQ4 CTPS1 GLCE	up	*
MIR4753_3P	0.0022088	0.0287139	0.4317077	-0.2215853	-1.289145	443	TRIM71 CXCL3 LPIN2 EDNRB GREB1 SOWAHC CPEB2 GREM2 PTPRB KL ARRDC4 ZBTB34 CGNL1 DDX6 NEDD4L CRY2 FLVCR2 SLC39A8 INPP5A CTDSP1 PRPF38A STX11 MEF2A KCNN3 TET2 ACER3 HEG1 RHOA ZEB2 SEMA6D DNAJC3 ZNF385D PPP1R15B PLXNA2 PAG1 DES SLAIN2 PLXNA4 SPTBN1 ZFYVE16 EPM2AIP1 ITSN2 PDE4D MYCT1 PDGFA PRDM16 KIAA0513 PIP5K1B REST PLEKHM3 DPH3 TBX5 RBM44 PDE1C BACE1 NCKAP5 IKZF5 CREM PHACTR2 PDCD6IP UTRN NDNF TMTC1 HRH1 APBB2 FBXO11 GLIPR1 TTC14 SP3 PIK3R1 SDHD KLHL18 SNX1 TMEM167B PRKACA PDZD2 CXCL5 RALB CELF2 GAS2L3 BLOC1S6 RNASEK YPEL2 HIVEP2 MARC2 PPP2CB GOLGA8R STXBP3 YTHDF2 CD86 PCDH17 SLC8A3 UTP3 WBP2 PLAA ADAM10 ABI3BP AMD1 RNF138 PDLIM5 RPP30 EPB41L5 SIK3 TOB2 RBM18 ALDH2 ALDH6A1 MEX3C OSER1 SCAI PAK2 TMEM87A LYST RORA CREG1 EHD4 PAPSS2 MS4A2 ZNF326 PSIP1 ACVR1C GREM1 SERPINE1 TNFSF8	down	*
MIR205_3P	0.0035997	0.0393860	0.4317077	-0.2245589	-1.285147	342	COL25A1 ZC3H12C ADCY9 NUP54 TMEM170B CAPN14 ELF2 C8orf58 RXFP1 NEDD9 C3orf70 TET2 MOB1B NFATC3 FAM49A SCARF1 PPM1D DPEP2 LACTB ENTPD1 SERINC1 CSGALNACT2 GLS PAG1 MS4A1 FAM122A TFEC CPED1 ROCK2 CASP1 PIP5K1B YBX3 RRM2B PLEKHM3 ABCC4 MGAT4A NKIRAS1 RECK CCSER2 CCDC59 ARL4A BCLAF1 NUS1 PDE1C SERTAD2 PDK4 RBM39 NEK7 MAML2 RGS18 LRCH1 APBB2 MBNL2 CREB1 CRYM MORC3 CAP1 NUDT15 HOMER1 SUCNR1 RASSF2 DENND4A ZNF407 GAS2L3 AGFG1 AZI2 MAPK8 XYLT1 AZIN1 GOLGA8R ZNF596 HECW1 GOLGA8H DYNC1LI1 ATXN1 TOB1 WBP2 ANKRD12 ADAM10 ARPP19 INO80D INTS6 PDLIM5 SFT2D1	down	*
MIR548AJ_3P_MIR548X_3P	0.0003007	0.0072507	0.4984931	-0.2060774	-1.283758	789	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C MBOAT2 RAB3C FYN CCL3L1 CALCRL QKI GTF2I SLC25A30 DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ACER3 ZEB2 ARHGAP29 SEMA6D CNST STARD4 MCTP1 HBEGF SGMS2 TM2D3 ADAM17 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L FOXJ3 PPP3CA RB1 TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FBXO8 FLI1 SLC7A2 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 PDE1C AFF1 BACE1 TLL1 CNOT6L LIN7A AFF3 STK24 USP25 SERTAD2 UFM1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM ASNSD1 YBX1 COPS2 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 NOTCH1 CPEB4 KCTD12 ETS1 MED30 BMP3 TMPRSS11D OSTM1 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 ZBTB24 MORC3 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS RHOQ PELI1 AGPS CDK17 KLB YTHDF3 PKD2 NAPG MAPK8 XYLT1 BTBD7 ING3 MME AZIN1 KIAA0232 DCK SERPINB1 PDS5B ABHD13 GNAI1 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 CDKN1C VPS4B CYP2U1 ITGAE ARL14EP UBE2D1 ZDHHC21 CREBBP SSH2 SOAT1 KPNA4 RBMS3 STAM2 BCAT1 SCAI PAK2 SKI NFU1 CECR2 FAM126B MMD CAMSAP2 C21orf91 TMCC3 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	**
MIR23C	0.0029663	0.0349648	0.4317077	-0.2155011	-1.282747	491	WEE1 EPAS1 TRHDE SOWAHC ZC3H12C CPEB2 PTPRB TTC7B RCOR1 ZBTB34 MED4 KIAA1109 NEDD4L CALCRL ZCCHC2 ELF2 INPP5A ARL8B MEF2A RXFP1 WBP4 LAMP1 AGPAT4 ZBTB2 TGFBR2 TRIB1 C12orf76 SEMA6D RAP1A MTF1 SWT1 ECHDC1 SERINC1 NLK GLS CAMTA1 ZEB1 MYCT1 TMEM38B SCP2 CLEC1A BNIP2 PPM1K TJP1 TMED5 GRK5 CDS2 PNRC1 ZBTB43 N4BP1 VEPH1 NUS1 CNOT6L VCPKMT NCOA1 C2orf69 LIN54 TMOD1 CDC40 PKNOX1 NEK7 MAML2 RAB8B PRPH2 SEC14L1 DDX47 MITF PNMA2 CARD8 MAP4K4 TBC1D12 PTGER4 DHX15 SDHD PRKCE GTDC1 DENND4A CGGBP1 CELF2 GAS2L3 CDK17 FOSB PKIA NAA16 NAP1L5 STRN NDUFA5 TGIF1 TEX30 CBFA2T3 ATXN1 MEIS1 WBP2 STX12 MICU3 ZNF267 PDE4B CCNH BNIP3L FGF2 INTS6 RPP30 SFT2D1 ORMDL1 TMOD2 UBE2D1 IPO5 FBXO25 MEX3C BRWD1 G3BP2 SSH2 KPNA4 STK4 CUL3 JMJD1C RNF38 PAK2 PTEN FAM126B CAMSAP2 RORA MT2A TLK1 SPOPL CNN2 LYZ ZBTB44 SNRPG MAP4 REEP1	down	*
MIR4659A_3P_MIR4659B_3P	0.0013138	0.0200070	0.4550599	-0.2103772	-1.279122	545	AJAP1 SC5D FOXF1 ABHD5 PHACTR1 SGK3 ADTRP CD55 ZC3H12C CPEB2 P2RY1 KCTD9 MED4 DDX6 CALCRL FLVCR2 AKAP7 NTM PAFAH1B2 MOB1B TLCD2 PPM1N ZEB2 EDEM1 NFIX HBEGF HECW2 LIFR ENTPD1 MTF1 ANXA5 NLK CSGALNACT2 RNF182 MED19 ADIPOR1 ZBTB8A DACH1 GATA3 PLXNA4 TRAF6 TNS1 SPTBN1 HPSE2 RAB14 CD58 FBXL5 KDSR CYBRD1 MTMR6 LIN7C ITM2B ZFAND5 STK17B THBS1 KLF7 NPR3 GPR85 CXXC4 PTGER3 ZMPSTE24 DSE RUFY3 AFF1 CRIM1 MEDAG RASGEF1B PDK4 SLC8A1 ID4 VPS37A CREM YBX1 PIKFYVE HCFC2 UTRN LRCH1 PNMA2 GABPA ZFP91 DESI2 JPH1 C11orf58 NXPE3 WTAP SKIL IFRD1 GLIPR1 TTC14 SP3 PIK3R1 CD83 FSD2 UNC13B WDR7 PALMD CACYBP ING3 ITGA9 PDS5B PCDH17 MYOCD ANKRD12 SBSPON RIMKLB CALB1 MBNL1 SYT11 HELZ MOB3B TNFAIP8 ALDH1B1 ARRB2 DCTN4 TIAM1 VPS4B DACT2 TAB2 RIPK2 DIXDC1 RBM18 ZDHHC21 CREBBP SSH2 RBMS3 KATNA1 ARPC5 FNIP2 CHCHD7 TMEM87A MTUS1 MMD C21orf91 THEMIS2 NRG1 NABP1 SFPQ CCDC144A	down	*
MIR335_3P	0.0007029	0.0131505	0.4772708	-0.2070508	-1.277562	720	CXCL3 EREG SWAP70 ABHD5 DLC1 SGK3 SOWAHC RBMS2 SLC16A12 SPN P2RY1 CLDND1 KCTD9 INSIG1 TRPC3 MMRN1 CCDC88A ST3GAL6 NEDD4L RTN3 THAP2 ZCCHC2 MTMR10 DYRK1A ELMO1 NR3C1 VAPA DSCAML1 TSHZ1 OTUD4 FAM49A ZEB2 DNAJB14 TOE1 RBM7 NCEH1 DNAJC3 TRA2B B3GNT5 UBL3 SLC36A4 SLC25A17 LIFR RAB33B TNIP3 ZBTB21 SLC7A11 ZNF697 PPP3CA ANKRD29 TMEM41B HERC3 BAG1 TIPARP CYBRD1 ROCK2 PER3 CCDC82 SGTB ADO HYPK RUNX1T1 REST PLEKHM3 TMED5 MYRIP ERP44 LRRC40 NPAS3 GPR85 CTBS ID2 ELK3 CPT1A PTCHD4 CUL5 ADAMTS8 MPC1 KIAA0408 PDE1C TBC1D4 ACTR2 ZNF426 ARL6IP5 CREBRF ETF1 ELF1 PDIK1L BCAR3 LRRTM2 DDHD1 PHACTR2 APPL1 RAB8B PIKFYVE NECAP1 TMTC1 CPEB4 GABPA ETS1 ADRA1A MSRB3 CCDC50 HSPA1B TMPRSS11D HELQ RAPGEF1 ELOVL7 ENPP4 PCGF5 COBLL1 ATL2 RC3H1 HSD17B12 RPS6KA1 TMEM167B NUDT15 HOMER1 PREX2 NAA30 WDR7 OCIAD1 MCAM AGFG1 POGLUT1 GPRIN3 FOS CALM1 NECAB1 YTHDF3 SRSF6 CCDC85A NAPG TTBK2 SPOP PBRM1 NIPA2 TCF4 STRN PDS5B FEM1B PDE12 ZCCHC10 MCUR1 PCDH17 CCDC68 GNB4 APLP2 THAP9 STON1 SBSPON RIMKLB KAT2B PHLPP2 HELZ NR2E3 RNF138 NEK1 PCM1 YAF2 CEP170 OPN3 B3GALNT1 MTO1 EPHA4 UBE2D1 NUP98 ZDHHC21 GRIN3A KPNA4 RND1 RBMS3 PARVA VSIG10 CUL3 PAK2 PTEN FAM126B PRKG1 GPR171 RORA	down	*
MIR93_5P	0.0019761	0.0264111	0.4317077	-0.2120269	-1.272594	529	RAB11FIP1 EREG TMEM100 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	*
MIR506_3P	0.0008762	0.0151786	0.4772708	-0.2070361	-1.266839	663	RAB11FIP1 SLC31A2 SEMA6A ABHD5 EDNRB OSBPL11 ADCY9 MBOAT2 CLDND1 RCOR1 EGR2 PLEKHF2 RGS9 CAV1 MYADM THAP2 QKI SLC25A30 MTMR10 CTDSP1 MEF2A TSHZ1 CBL GGA2 CASP9 EDEM1 SEMA6D SH2B3 NFIX TTL CYB5A ZNF503 ANXA5 FZD4 LITAF HIPK3 KLF6 LCP1 STOM NR4A1 MED26 SLC25A37 AKT3 PTPN12 EFCAB14 AMOTL1 DUSP3 LRRC57 DENND6A LIMS1 ZCCHC24 PLEKHM3 ROCK1 USP2 TNFSF15 CEBPA MYRIP KIF26A ABCC4 SNIP1 TMBIM1 SSH1 ATL3 MGAT4A RBMS1 VIM TADA2B C9orf72 JAM2 PIK3C2A ELK3 WDR48 ZMPSTE24 CPT1A CUL5 ILDR2 ZNF706 MYH11 FKBP15 KPNA3 TLL1 LMBRD1 RSRC2 C2orf69 SERTAD2 KANK1 MYLIP MYO1C CREBRF VAMP3 GZF1 WASF2 SGK1 PHACTR2 UBQLN3 ARL5B MITF VAT1 ETS1 DNASE2 RHOG APBB2 RAPGEF1 WTAP FERMT2 ENPP4 EEA1 PI4K2B GRB2 MAPK4 RPS6KA1 SLC10A7 FAM177A1 THSD7B GFPT2 PPM1F ACSL1 BLOC1S6 CD151 POGLUT1 ADNP2 RHOQ PNPLA2 CD164 HIVEP2 ECI2 SRSF6 XYLT1 NAP1L5 CPA3 EPHA3 TFEB PEA15 ZBTB11 GNAI1 MCUR1 MAP3K2 PIM1 ORC2 PHF19 GATA6 PDE4B RXRA ANKLE2 PDLIM5 SLC31A1 PUS10 DCTN4 TMEM184B RBMS3 ULK2 TMEM109 KLLN KATNA1 LIMCH1 BCAT1 RASSF8 SNAP29 PRKG1 ANXA11 NR3C2 NAA15 IQGAP1 WDFY3 SPOPL ENY2 SLC44A5 EVI5 PAPSS2 GPALPP1 FNBP1 REEP1 SUGT1 EGR1 CHP1 CDON CHIC2 SLC25A38 SPPL2A SVIL KCNJ6 ENDOD1 HIPK1 USP30 CLOCK MYH10 ITGB1	down	*
MIR548E_5P	0.0040377	0.0425552	0.4070179	-0.2061572	-1.261858	619	CXCL16 CPEB2 MNDA ATXN3 PRKG2 ADCY9 RDX KCTD9 PID1 BDNF TXNL1 BAG4 KIAA1109 CALCRL QKI DYRK1A PRKAR1A NR3C1 TET2 MOB1B NFATC3 ARHGAP29 CD36 ATP2B1 LACTB STARD9 RRAGC ASAP1 SLC36A4 LIFR LATS2 ZDHHC2 SERINC1 FOXP1 HIPK3 GLS PRSS12 ADIPOR1 FOXJ3 JAM3 RB1 RGCC TRAF6 HERC3 ADARB1 AGO4 RAB12 CCDC82 DGKE LIN7C ZSWIM6 RUNX1T1 ZNF423 HAUS2 RRM2B KLF9 UHRF1BP1L ARNTL SOCS5 FBXL3 FAM49B SPAG9 UBQLN1 PER2 DOCK9 MARVELD1 PDE3B NR1D2 VIM CTBS CEP57 PIK3C2A GCA LYAR N4BP2L1 PPP2R5A SLC6A6 CALM2 FAM76B CNOT6L CDKN2AIP NCOA1 RAB6A USP25 RBPJ CREBRF FRY GZF1 SAR1A HCFC2 SRSF3 TMTC1 LRCH1 ZFP91 NSMCE2 ETS1 BMP3 NXPE3 UHRF2 APBB2 RCAN1 EEA1 FRYL CREB1 FSD2 RC3H1 PDZD2 ZNRF3 THSD7B PREX2 NIPSNAP3B ZNF407 CELF2 NAP1L5 MME STRN ABHD13 MAP3K2 PCDH17 ATXN1 PHF19 GNB4 BRI3 ANKRD13A STON1 STK40 NPTN CLASP2 RIMKLB KANSL2 KIF17 PLAA ADAM10 ARPP19 RBL2 RNF138 SESN1 PCM1 ABL2 CTTNBP2NL SFT2D1 TFPI IER5 PIP4K2A DIXDC1 CYP2U1 ZDHHC21 RBMS3 MBD5 HNRNPC TTC28 MAFK RNF38 ST6GAL2 TMEM87A TLK2 RORA ITCH DOCK4 GSPT1 SCLT1 AFTPH UBE2V1 PSIP1 HERPUD1 KALRN TBPL1 SPPL2A TMEM30A HIPK1 ATF2 USP30 LHFPL2 CLOCK MAMDC2 SLC38A2 KMT2E NDFIP1	down	*
LHX2_TARGET_GENES	0.0029080	0.0346641	0.4317077	0.2463729	1.261654	1124	ATP10B PDE11A PRR15 PPM1H SYT8 CEACAM1 PRLR STYK1 EGLN3 CDH17 LAD1 GMDS RPGRIP1L BUB1B IGF2BP3 DROSHA CIB2 TTF2 CHCHD6 NUDCD3 NDC80 GUCY2C PRIM2 TBRG4 ZNF138 MRPL46 TUBB2B C6orf141 PRR15L KIF14 STK31 ANKRD24 COL7A1 CDCA8 ACAD9 ALDH18A1 ECT2 CDC6 ACOT8 NNT GOLGB1 SPATS2 STRIP2 BCL2L14 TYMS XPNPEP1 PMS2 NWD1 EFNA5 PLS1 ZFYVE19 ZNF3 CAND1 VILL NCAPD2 ZNF608 UQCC1 NME1 AARS2 WDR62 RSPH1 TMEM41A SDR16C5 EXO1 ZNF391 SYTL2 PCCB KIF3B RPL32P3 AURKA NUP155 THBS4 MYO10 C1orf226 LARS2 TPR SMARCAL1 E2F2 ZNF860 TTC22 CDCA5 CDNF SETDB1 ERAL1 AIMP2 EMG1 ZNF785 TARS2 WDR60 PSMG4 EGFR OAZ3 ZNF443 LINC00265 ZNHIT1 C7orf50 PEX26 ACTL6A PIH1D1 MRPS11 DNAH11 FDXR SAMD10 GRHL2 PHB FADS2 ERCC2 PIGO SRRM5 UQCR11 CNPY2 POLN TNIK CDKN2C CAPN8 FRMD5 FAHD2A KRT18 DMKN PABPN1 HDGF CDK12 EPHA1 SSBP1 PICK1 PACS1 TNK2 AAGAB ADAP1 NCAPG PSMB5 PRPF6 SDCBP2 ENPP3 FEN1 CDH3 TTC6 TMEM79 PSMG3 LINC00649 METTL3 THAP8 USP42 MYO5B MTBP PSMC4 TSPAN1 CENPP FOCAD DNAJC7 UNC45A TPD52L2 RNF44 HYKK ILF2 DNAJC17 VIPAS39 C19orf44 SATB2 DCAKD SMG5 NDUFA11 VPS41 DNAH7 JOSD2 LRFN3 MAN1B1 ARHGAP32 CCDC151 GPRC5C SLC37A4 RAD51D ACBD4 PPOX KIF21A MSI2 CSNK1G1 CCDC146 FZR1 LIN37 ZSWIM3 ZSWIM1 GFM2 C15orf41 CKMT2-AS1 IQCH CDK13 LTBR FAM200A FLG-AS1 CCDC159 ENC1 NIF3L1 CENPK FAM71E1 EFCAB7 LIMA1 L3MBTL2 WDR34 TUBG2 ZCCHC17 FAF1 HMGB3P22 NOL6 ABCC3 KRT8 MRPL24 KDM4B MRPS33 WDR83 RPL7L1 CENPT ZSWIM8 NSUN6 KPTN SPINK5 C1orf56 SLC35A3 SCYL3 C1orf109 TBC1D16 GINS3 FBXO36 HOXA-AS3 SNX11 NEURL4 MRPL51 CYP4F12 MIB2 HAUS4 SLC1A5 PALM3 NEDD8 VPS53 SF3A2 ATAD2 GOSR2 EIF3K DUS2 SPSB3 KLHL7 SH3D21 NME1-NME2 AMN1 PRPF18 RPS26 RRNAD1 TM7SF3 DBNL BBX MANBAL MRPS25 DTNB CTU1 STAT6 ZNF436 CCDC9 PRPF31 HAS1 NUBP2 OSBPL10 BMS1 CAPN10 TRIP4 BRMS1 PFKM ST20 ZNF217 SAMD4B MRPL9 ZSCAN22 MICU1 SNRNP200 TMEM101 ERBB2 TBC1D32 CPOX ZNF131 SIRT6 BCAS3 BCL6 GMPR2 XPC TCF3 DNAJC14 ADAM15 FZD3 POP4 GLYCTK ZMAT2 ALG1 GGCX NMT1 ZNF526 IDUA SNRPC TTC30B TBL3 NCAPD3 CDKAL1 SFXN5 TMEM38A ZER1 STK11IP IMMP2L CLASP1 ILVBL FAM222B SCAF1 ZNF337 FTSJ3 TRAPPC6A KCNK6 ANKRD11 ANKRD13D ALKBH2 CLNS1A CSTF1 COPE FAM47E INO80B NDUFAF6 HEXIM2 VPS26B DCAF16 PDXP MRTO4 CFI MBTD1 HGD DHDDS RFFL PPP1R13L CXorf40A ITGB5 METTL4 PM20D2 MED15	up	*
MIR124_3P	0.0010885	0.0174151	0.4550599	-0.2056587	-1.260808	661	RAB11FIP1 SLC31A2 SEMA6A ABHD5 EDNRB OSBPL11 ADCY9 MBOAT2 CLDND1 RCOR1 EGR2 PLEKHF2 RGS9 CAV1 MYADM THAP2 QKI SLC25A30 MTMR10 CTDSP1 MEF2A TSHZ1 CBL GGA2 CASP9 EDEM1 SEMA6D SH2B3 NFIX TTL CYB5A ZNF503 ANXA5 FZD4 LITAF HIPK3 KLF6 LCP1 STOM NR4A1 MED26 SLC25A37 AKT3 PTPN12 EFCAB14 AMOTL1 DUSP3 LRRC57 DENND6A LIMS1 ZCCHC24 PLEKHM3 ROCK1 USP2 TNFSF15 CEBPA MYRIP KIF26A ABCC4 SNIP1 TMBIM1 SSH1 ATL3 MGAT4A RBMS1 VIM TADA2B C9orf72 JAM2 PIK3C2A ELK3 ZMPSTE24 CPT1A CUL5 ILDR2 ZNF706 MYH11 FKBP15 KPNA3 TLL1 LMBRD1 RSRC2 C2orf69 SERTAD2 KANK1 MYLIP MYO1C CREBRF VAMP3 GZF1 WASF2 SGK1 PHACTR2 UBQLN3 ARL5B MITF VAT1 ETS1 DNASE2 RHOG APBB2 RAPGEF1 WTAP FERMT2 ENPP4 EEA1 PI4K2B GRB2 MAPK4 RPS6KA1 SLC10A7 FAM177A1 THSD7B GFPT2 PPM1F ACSL1 BLOC1S6 CD151 POGLUT1 ADNP2 RHOQ PNPLA2 CD164 HIVEP2 ECI2 SRSF6 XYLT1 NAP1L5 CPA3 EPHA3 TFEB PEA15 ZBTB11 GNAI1 MCUR1 MAP3K2 PIM1 ORC2 PHF19 GATA6 PDE4B RXRA ANKLE2 PDLIM5 SLC31A1 PUS10 DCTN4 TMEM184B RBMS3 ULK2 TMEM109 KLLN KATNA1 LIMCH1 BCAT1 RASSF8 SNAP29 PRKG1 ANXA11 NR3C2 NAA15 IQGAP1 WDFY3 SPOPL ENY2 SLC44A5 EVI5 PAPSS2 GPALPP1 FNBP1 REEP1 SUGT1 EGR1 CHP1 CDON CHIC2 SLC25A38 SPPL2A SVIL KCNJ6 ENDOD1 HIPK1 USP30 CLOCK MYH10 ITGB1	down	*
TET1_TARGET_GENES	0.0031019	0.0356518	0.4317077	0.2454897	1.254209	1037	CPNE4 RIBC2 ONECUT1 CA9 GPR89A IGSF9 HJURP DNAH2 PARPBP TFAP2A PROM1 NEK2 COIL UCHL1 DROSHA C17orf75 PAIP1 SORD THEM4 CDCA7 SIX4 TUBB2B GINS1 AGFG2 ASIC1 ANLN CCDC14 POLE STIL DGCR8 NUF2 AURKB CENPA PTTG1 WDR70 TMEM254-AS1 CDC6 ZNF714 STRIP2 CDC25A PLS1 TDRKH COPB2 KIAA0895 LIPE-AS1 CAND1 NCAPD2 SPDL1 UQCC1 LSM5 DNAI1 RUVBL2 SOX30 OSBPL2 CHAF1A ZFYVE27 GFPT1 ZNF850 DCBLD2 SPAG16 QTRT1 STAP2 PCCB COPG2 MAP3K13 KIF3B EME1 SPTB PCDHGC4 C20orf96 SAE1 ATR GTPBP3 TMEM132A IRF3 ZNF174 HYDIN ICA1 COASY DPCD TTLL12 MMS22L CDCA5 AKAP1 ADM2 RAD54L MRPL27 ANKMY1 SEC61A1 TARS2 LETMD1 PPP1R35 TMEM200C TOPBP1 ZYG11A PEX26 NFYA GAS8 RAD51AP1 EHHADH ABCB9 DNAAF3 TBC1D8 CAD ETFA SPAG8 OGFOD2 FADS2 KLHL3 NOL3 CNOT3 HSPBP1 CNPY2 SKP2 TNIK GPX8 TTBK1 ISOC2 TERC CMAS ANAPC5 ING4 RNPC3 CDK12 SRRM2-AS1 TNFRSF21 FAM135A MERTK CENPH ZNF260 NUDT2 KIAA0753 PHF12 ZSCAN25 ANKRD54 NAV2 POC5 NCAPG STX18 KCTD13 DHX37 TRIM41 ENPP3 ITPKA FEN1 TSPAN31 CNOT11 TMEM79 LRRC42 RAB11FIP4 SLC12A8 OARD1 TMEM120B SNRPE ZKSCAN5 RANGAP1 MZT2B ILF2 THNSL1 ATP7B SMG5 NDUFA11 C19orf47 DHX40 GALK2 TSNAXIP1 AGL JOSD2 ADAT1 NINL EFCAB2 POLL RAD9A COG2 KIF22 IQCG CCDC130 TMEM237 ROGDI COPS7B ZNF544 CHTF18 CSNK1G1 PDRG1 PCDH9 ZNF300 TJAP1 ITFG2 STX18-AS1 ENOSF1 GFM2 TM9SF4 BCL2L12 MAGOHB TYRO3 CABLES2 ELAC2 CNDP2 CCT7 SLX4IP RAD50 RNF187 TADA3 ZNF782 CENPV TUBG2 EFHC1 GPATCH4 FAHD1 MRPS23 RPUSD1 GMPPA FANCM MCM6 METTL2B EML6 PPCDC CKAP2 ZRANB3 C5orf22 LANCL2 LTV1 EIF3D ZSCAN32 SNX11 STMN3 NDUFS7 MYEF2 MRPL51 PIGX PDIA4 TMEM254 GOSR2 ZNF286A ZKSCAN7 ZNF224 CYTH2 RPS26 NCDN DOCK3 TRERF1 BBX PLSCR2 DENR CDC42BPA RFC5 WDR77 BMS1 ENKUR MLLT1 GTF3C5 KIAA0825 TMEM44-AS1 SNRNP70 SNORA14B ETHE1 AURKAIP1 VDAC3 TNS3 SLC12A2 ARHGEF39 ZNF131 SYNRG B4GALNT3 BCL6 GOSR1 XPC TCF3 POLR1A ZNF793 PFDN4 MTHFD1 TP53 PDZD7 LRSAM1 MON2 PRPF3 TMEM9B-AS1 EPHB4 DCDC1 NCAPD3 BCAT2 SART1 NUP210 MRPL48 ATF7IP IMMP2L FAM219A TIPRL PCTP PRKAG1 TMEM169 PHRF1 TEX9 LMBRD2 KIAA0586 TOMM7 RTN4IP1 ZNF554 EIF2D RPL23A VPS26B DCAF16 MRTO4	up	*
MIR548F_5P	0.0047115	0.0477683	0.4070179	-0.2160437	-1.252413	391	PRMT8 SECISBP2L RBMS2 LRRFIP1 INSIG1 KLHL8 STXBP6 TXNL1 LONRF1 NEDD4L BMPR2 PLEKHA1 S1PR1 MEF2A WBP4 TGFBR2 CCNL1 ZEB2 TRA2B HECW2 PPP1R15B RASGRP4 MTF1 KLF10 HIPK3 GLS GPBP1L1 PEX5L PLXNA4 GPM6A ATP6V1B2 FBXO8 MAP2K3 PRDM16 C14orf132 SORBS1 BNIP2 PIP5K1B ST3GAL2 RUNX1T1 MAFG KLF7 SNIP1 DOCK9 RBMS1 GPR85 EPS15 CLIP4 SLC6A6 C1QTNF2 FAM76B MAPRE2 FOXN3 USP25 TMEM9B CREBRF HCFC2 TMTC1 PDE5A BMP3 MSRB3 ATP11A UHRF2 SMU1 PCGF5 IDS FAM43A CREB1 KBTBD8 RC3H1 CGGBP1 EPC2 YTHDF3 PPTC7 MAPK8 MYL12A TSHZ3 TRAPPC10 XYLT1 FLNC BTBD7 DDHD2 TCF4 STRN SMCR8 PPP3R1 ACADL NPTN ACYP2 ADAMTS15 ATAD2B ARPP19 INO80D SYT11 MIER1 MGAT2 SETDB2 TDRP DAPK1 PALD1 EPB41L4A FOXJ2 B3GNT2 TMCC3 CNTNAP3B C2orf42 GSPT1 PUM1 SMAD4 AFTPH ABI1 USP4 CFL2 CLIP1 ATP11B LNPEP CLOCK MAMDC2 KBTBD11 KMT2E CBR4 FAR1 PIGK CTDSPL2	down	*
MIR20B_5P	0.0030639	0.0353912	0.4317077	-0.2087827	-1.250851	530	RAB11FIP1 EREG TMEM100 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	*
CREB3L4_TARGET_GENES	0.0029801	0.0349648	0.4317077	0.2438356	1.250338	1161	COL17A1 ANKRD18A PRLR FAM201A MUC13 ZDHHC8P1 HOXB-AS3 CNGA1 WFDC3 RPGRIP1L NEK2 COIL CYP2J2 PSPH TTF2 GCNT3 THEM4 CDCA7 ECE2 TMC1 GINS1 CDCA2 CDK4 PRR15L BCL2L15 NAALADL2 FLAD1 SAP30L-AS1 DGCR8 YEATS4 AURKB ALDH18A1 PAK6 CCNB2 ACER2 SLC35E3 BCL2L14 RAD54B TYMS GRHL3 ZNF117 FERMT1 ERV3-1 GALNT10 EIF3B CIB1 TMCC1 CCT6A XPO5 KIAA0895 LIPE-AS1 GINS4 KIF27 RCCD1 XPOT ZFP64 ZWINT NUB1 KAZALD1 MAGEF1 AARS2 WDR62 CLPTM1L CASP2 ZNF391 TP53BP1 AURKA THBS4 NDUFS2 SAE1 POLD2 SFI1 SMARCAL1 KIF2C ZNF860 MPHOSPH9 RRM2 RGL1 LIPE SETDB1 ZNHIT6 AMACR PKM WDR73 LMNB1 CDC25C XXYLT1 EMG1 ZNF785 RNFT2 LRRC66 PSMG4 OAZ3 CD24 CHEK1 SCAMP5 SRD5A3-AS1 CENPO COX19 ZKSCAN1 SPATA17 FNTB REPIN1 MRPS30 LRRC45 SLC18B1 COMMD4 C2CD3 FBXO16 DET1 NIPAL1 ALG3 PIGO SPRY1 SRRM5 R3HDM2 CNPY2 PPP1R37 CASP6 KNSTRN RASSF6 CAPN8 PPIL2 NUSAP1 TMEM106C CDK12 PPIC DNTTIP1 KCTD7 FAM135A PICK1 ESRP1 GOT2 DIS3L2 OAT NPM3 VPS28 CCNJL L2HGDH DGAT2 PMEL ENPP3 ITPKA PDK1 EZH2 ACTR3B METTL3 RNF207 SF3B3 TNRC18 LCA5 ATAD3A GOLGA5 NLN HMGXB3 PBLD PSMC4 TSPAN1 CENPP UBN2 EIF6 RNF44 EFTUD2 NET1 DNMT1 GOLGA3 ELMOD3 PELP1 ILF2 RHOC COL1A1 VIPAS39 SCLY CCDC134 PSMA5 PUS1 EFCAB2 MNS1 MAN1B1 LLGL2 S100A16 ARHGAP32 TRIO OSBPL3 PTGES2 PIGG HIRA MRPL52 UBE3D TIGD6 CCDC130 COX7C FBXO15 DPH2 AKAP8L MLEC MSI2 LMTK2 ANP32E PKP4 NUDT16 PRMT7 TM9SF4 ANAPC1 COG4 TSEN54 ZNF282 NUP85 FAM200A ZBTB45 PPME1 GALNT7 CLTB TMEM232 CCT7 ANKRD31 KLC2 BAZ2A FAM71E1 TADA3 LSG1 LINC00910 CPSF4 PWWP2A DGKA STOML2 AAAS CA11 GBF1 MAN2A1 C12orf65 ZNF616 MRPS23 PPP6R1 SRRT PHYKPL KRT8 ASRGL1 MCM6 KDM4B CYP2S1 ODF3B XRCC4 MCM5 RPPH1 USP21 WDR35 ACOT11 ZRANB3 DDX23 HAUS6 RABEPK SLC35A3 HAX1 C1orf109 SNX11 AATF EXOSC5 MRPL51 CCNG1 RPP38 SF3A2 CDH11 TSR1 TCERG1 COPZ1 ALG8 EPCAM LRRC14 AMN1 GLO1 B9D1 TM7SF3 CCNA2 SMARCA4 DBNL CISD3 DDX54 DENR RFC5 DOHH BLVRB ACKR2 CEP164 WDR77 VPS33B OSBPL10 RAD51 TTC1 ZNF384 CHMP1A ARHGAP5 ARHGAP11A SCOC MRPL9 RDH10 PAXIP1 SNRNP70 NME7 VPS9D1 ACP1 FAM118B SNX8 DIP2B UQCRQ ZNF131 TCF3 PFDN4 GLYCTK MTHFD1 TIMM44 CCDC122 SLC36A1 PPIA UBE2C PTOV1 NELFA SFXN5 ULBP3 ENO1 RAD1 MUC1 COX6B1 RNF32 NUP93 THRB-AS1 DDX41 BRIX1 C12orf10 MSANTD4 RAD51-AS1 PRKAG1 GEMIN2 PARP2 PCGF6 CLNS1A TTC5 TFB1M CSTF1 FAM47E RTN4IP1 ZNF740 VPS18 PDXP WDR55 MED22 DHDDS DEPDC4 MAN2C1 MED15 SH3RF2 ASPH TRIM52 PTPRK PRPF19 TMEM259 DEPDC5 FOXP2 ZNF276 PSMB10 ZNF688 LGR4 SDHAF1 TNPO3 USP35	up	*
BARX1_TARGET_GENES	0.0041984	0.0437208	0.4070179	0.2447835	1.249740	1018	COL17A1 TSPAN8 PDE11A FOXA3 CDH17 HJURP RUVBL1 CEP89 CDC45 TICRR DNAH2 BUB1B CCDC127 NEK2 CENPF COA1 PSPH SLC2A1 DDIT4 NDC80 TTC25 PIF1 DEPDC1B GINS1 CDCA2 EFNA3 PRR15L IQGAP3 UBE2Z EIF2B5 ANKRD24 FLAD1 PLK1 NUF2 YEATS4 EFNA4 CDCA8 CENPA TPX2 BCL2L14 XRCC2 TDRKH CCT6A GON4L XPOT ZWINT KAZALD1 TAMM41 FAM220A HAUS5 TJP3 RSPH1 POLR3A BZW2 EXO1 RAB11B-AS1 XPNPEP3 SDHA ZFYVE27 MRPL15 POLM COPG1 AP4M1 WASF1 KIF3B TOP2A EME1 IQCD PMS2P4 THBS4 METTL7B SAE1 LARS2 MCM7 ZNF860 POC1A RSRC1 TPCN1 RRM2 CDCA5 MRPL27 BLOC1S1 ZNF785 AP1M2 ZNF786 ACTL6A NFYA PSMD4 DCTPP1 TIMM50 ZNF48 SPATA17 EHF SYMPK FBXO16 ARL16 ALDOA PIGO TULP3 R3HDM2 PPP1R37 INCENP RBAK CKS1B ISOC2 CDKN2C PPIL2 TMEM106C ANAPC5 PABPN1 HDGF CDK12 WDR5B SSBP1 MCTP2 SRRM2-AS1 KCTD7 CCT3 EEPD1 GMNN SUN1 POC5 ITGB8 ACP6 GIPR SMG9 PMEL RNF181 ZNF584 TSPAN31 ZNF775 TMEM79 SPAG5 LINC00649 OARD1 MTBP C9orf43 ANXA2R IFT52 UBN2 UNC45A EIF6 DHX34 POLR2H GIPC1 DNMT1 ILF2 DLGAP5 CCDC134 SMG5 NDUFA11 SLC26A2 FAM47E-STBD1 AGL MTOR PUS1 MAN1B1 PSME2 TRIM37 DUSP12 FBXO15 PPOX NFATC4 CENPQ RHBDD3 CSNK1G1 SOX2-OT OS9 CCDC146 HECTD1 GEMIN5 ITFG2 SLC4A2 DNMBP SND1 CDK13 PRRG2 ZBTB45 ENC1 NIF3L1 SLX4IP NR6A1 ABCC10 FAM71E1 SUPT16H STAG3L4 LIMA1 CKAP5 L3MBTL2 PWWP2A CDC20 AAAS CCDC30 SIRT4 EFHC1 ASCC1 ACLY PPP6R1 FITM2 SRRT ABCA7 CLINT1 KRT8 MRPL24 PEX5 KDM4B BLCAP METTL2B ZNF446 DHX8 NOSIP NMNAT1 EIF3D SCYL3 HAX1 C1orf109 HOXA-AS3 AATF DOLPP1 DUS4L HAUS4 LSM4 TXNL4A RNF31 STK35 MST1P2 DUS2 SPSB3 NUP62 DPH5 AMN1 PMS1 B9D1 CYTH2 ADM CISD3 GTF3C2 SNRPD2 DOHH PAK4 ABCF2 CCDC9 PRPF31 CLUAP1 INO80E NUBP2 OSBPL10 TNKS1BP1 TRAPPC9 TOMM40L RNF123 PFKM ARHGAP11A TAB1 SAMD4B RPRD2 IKZF4 CDK5 FAM118B MXD3 UQCRQ ZNF131 SIRT6 BCL6 CENPE ANKMY2 DNAJC14 HGS UBE2C TTC9C NCAPD3 BTN2A1 TUBA1C ZSCAN20 ATF7IP TAX1BP1 DNM1L CLASP1 NUP93 SCAF1 MOK MZF1 C12orf10 TRAPPC6A SETD5 TIPRL FBXL18 PRKAG1 ALKBH2 PHRF1 RPUSD3 FAM47E VPS26B PLAC8 VPS18 SETD1A WDR55 MBTD1 DEPDC4 ASB16-AS1 PPP1R13L METTL4 SH3RF2 UTP18 PTPRK PARL MST1 RPL36 FOXP2 ZNF514 PSMB10 MRPL43 ABHD2 TNPO3 NFE2L1 USP35	up	*
MIR8485	0.0009266	0.0155027	0.4772708	-0.1976426	-1.242418	852	SMAD6 AJAP1 COL25A1 SCN4A C2orf91 DLC1 ADPRH TAL1 ZC3H12C SPN P2RY1 PTP4A2 RDX CLEC12A DPYSL2 BMPER MBOAT2 CYP4B1 RAB3C BTNL9 BMP2 SIK1 ZBTB34 ARHGEF15 IBA57 BACH1 LONRF1 CORO1C MYADM CRY2 FLVCR2 VAMP2 ADCYAP1R1 ARL8B DYRK1A MEF2A KCNN3 VAPA CBL ZBTB2 FAM49A GGA2 SEMA6D ZBTB4 CD36 UBR3 KIAA0355 PLA2G7 LIFR TNIP3 RNF144B NLK SPIRE1 FOXP1 KLF6 SLC7A11 ADRB1 SLAIN2 FOXJ3 MOB3C PLXNA4 SLC25A37 CD93 LAMTOR3 PPP1R13B ZYG11B SLC7A2 STAT5A AMOTL1 NRARP TIMM10B FOXO1 TBX4 SDCBP ZSWIM6 ZCCHC24 HAUS2 MVB12B STK17B ADAMTS9 SSH1 P2RY2 NPAS3 PTPRC CXXC4 RECK LBH ELK3 EVI2A PPP2R5C PEAK1 SLC6A6 UNC5A KIAA0408 CYP26B1 PRDM5 NUS1 AFF1 CRIM1 SEC31A RASL12 AFF3 SIAH1 TGFB2 PIAS1 CLN8 SRF PDK4 SPIN1 MOB4 RBPJ SLC8A1 FLT1 METAP1 SYNPO2 PKNOX1 MED28 SGK1 KIF13A HSD17B13 EBF2 NEK7 PDCD6IP CNTN3 AQP3 C2CD2 VAT1 WSCD2 ETS1 DESI2 CELF1 JUNB ARHGEF10 RABGAP1 UHRF2 MTMR9 IQSEC3 SKIL ENPP4 HUNK PIK3R1 HSPA13 DDX5 GRB2 THUMPD1 FRYL COBLL1 SIGLEC15 ATP13A3 RASSF2 CASZ1 TIGIT SNRK MCAM ATP6V0D1 AGPS PNPLA2 NECAB1 USP7 CCDC85A DGKG ZFAND6 SORT1 FXYD6 DDHD2 STRN AP1G1 PHF3 KIAA0232 NDUFA5 CCP110 GNAI1 NAB1 C16orf72 DYNC1LI1 CNOT7 MAP3K2 NFYC GNB4 ADPGK THAP11 ACYP2 SPOCK2 TCF7L1 SMAD2 INO80D JUND RNF138 ABL2 GSTM5 CTTNBP2NL ADAMTS4 SEC63 PIP4K2A CYB5R4 TMOD2 EPHA4 ARIH1 PTCH1 ILKAP IPO5 MEGF9 ZDHHC21 SSH2 ISCU KPNA4 PARVA CD19 STAM2 ANKRD49 SIN3A RNF38 PTEN DNAJB9 TLK2 FAM126B TNFSF9 SYNPO2L C21orf91 RORA COL13A1 DAZAP2 NRP2 DOCK4	down	*
THAP1_TARGET_GENES	0.0025843	0.0317170	0.4317077	0.2399138	1.237864	1589	MIR210HG WFDC3 RUVBL1 CDC45 MCM10 DEPTOR C5orf63 ABCA17P COIL CCNB1 DROSHA C17orf75 GBAP1 NUDCD3 TTC25 MKS1 CCDC113 TBRG4 AGFG2 RACGAP1 LRRC37A3 ANKRD24 NDUFS6 NUF2 WDR70 RAB36 UMPS CKLF-CMTM1 COCH PRC1 ORC1 ACY1 CIB1 GON4L MIS18A ZNF3 KIF27 RCCD1 XPOT DNAH14 UQCC1 WDR90 AARS2 SIPA1L3 TOP3B RANBP1 CEP250 CLPTM1L C5orf34 NEURL2 DNPH1 CISD1 SMARCC1 RPL39L BBS1 C9orf116 BOD1 QTRT1 CUL7 KIF15 FOXJ1 AP4M1 FRS2 TIGD4 EEF1E1 RPL32P3 CENPL RFXANK AURKA NUP155 WDR3 NDUFS2 ATR YKT6 GTPBP3 KIF2C MCM7 RSRC1 COASY ABCC5 RNF157-AS1 NSUN2 CDNF CCDC114 FANCD2 TRPT1 ZNF226 EMG1 ZNF785 PYCR2 SLC37A3 WDR60 EME2 ZNHIT1 BCL2L2-PABPN1 C7orf50 IFT172 HSF2BP TRMT61B SRD5A3-AS1 CENPO COX19 TRMT2A AKT2 B4GALT7 GEMIN7 EEFSEC CAD ZNF507 FNTB SAMD10 SLC35E2B PROB1 ZNF713 HSPBP1 COQ9 SKP2 RECQL5 DHRS13 CKLF GEMIN8P4 CKS1B MRPL36 EFCAB11 CDKN2C HPS4 MEA1 DDX51 HARS2 ASF1B ANAPC5 ING4 PABPN1 POLE2 DNTTIP1 EXOSC2 DIDO1 WDR54 PHF12 DCBLD1 TYW1 RBCK1 STX18 REEP6 PSMB5 MCAT MRPS2 PRPF6 AP5Z1 PMEL PODNL1 TRIM41 ENPP3 ZNF584 PSAT1 DPH7 KRBA1 TMEM79 ACTR3B LINC00649 FADD METTL3 RAB11FIP4 USP42 ATAD3A TTC16 HMGXB3 CCDC57 FAM102A PSMC4 CENPP SRD5A1 PA2G4 TPD52L2 FAM86C1 EFTUD2 CHCHD2 MZT2A DNMT1 PARS2 CATSPERG MZT2B G6PC3 ZGPAT ILF2 ARFRP1 CCDC142 TSPAN17 PABPC1L POFUT1 TUBG1 DCLRE1C SCLY SMG5 WDR53 ARHGEF16 NFS1 UBAC1 GALK2 ENTPD3-AS1 PSMA5 TRMU ADNP DNAJA3 NMRAL1 TACC3 MAN1B1 RAD9A MRPS34 LONP1 GALNS DHODH PKP3 PIGG HIRA TIGD6 CCDC130 LMF1 FBXO15 UBE2Q1 PPOX CHTF18 PCSK4 STOML1 MSRB2 JMJD4 ESCO2 MLEC OS9 MRPL4 PCDH9 STX18-AS1 LIN37 ASNS TM9SF4 ANAPC1 C15orf41 CKMT2-AS1 NRF1 POLD1 C12orf73 GNAZ PEX10 ZBTB45 TAPT1-AS1 NAIF1 COPS6 CCT7 YARS2 ARHGAP12 SLX4IP RAD50 CCDC137 ABCC10 SASS6 EPN1 KLHDC3 SH2B1 TADA3 PTER EP400 FN3KRP CPSF4 COG1 TMEM106B AHCYL1 WDR34 NPRL3 PPP1R8 EFHC1 FAF1 DUS1L RRP9 MRPS23 ACLY ZNF497 RPA1 PPP6R1 FIBCD1 RPUSD1 ARHGAP22 BAD ABCC3 MADCAM1 CDK5RAP2 MGME1 ZNF160 GID8 ZSWIM8 XRCC4 SLC38A7 ROMO1 NOC4L USP21 KPTN NMNAT1 CD2BP2 TDP1 SIRT5 DDX23 SNAP47 C5orf22 LANCL2 PYGO2 EIF3D SCYL3 URB1 NFE2 SNX11 ADCK1 KATNB1 NEURL4 DUS4L POLR3E IGHMBP2 TXNL4A AP4B1 PPP1R3E SH3BP5L LHPP RRP36 DDX55 CEP152 MST1P2 ALG8 SPSB3 PRMT5 TMEM17 NDUFV1 COG5 AMN1 TSPAN10 ZNF212 RPS26 RRNAD1 NCDN SMARCA4 ULK4 SLC2A5 ECH1 ZNF445 GTF3C2 MANBAL CANT1 PDF POLR3B MRPL55 CSNK1G2 TXNL4B AMDHD2 PCBD2 CTU1 ZNF436 CDK5RAP1 TTC31 CCDC9 ACSF3 NUBP2 HOOK2 N6AMT1 ZNF384 ZNF292 SEC13 TOMM40L RNF123 KCTD21-AS1 MARK4 SUPT3H SAMD4B SRP9 MRPL21 SNRNP70 VPS9D1 ACP1 FAM118B DNPEP SNX8 RHOT2 AGBL5 TMEM101 AURKAIP1 CASC2 CIAPIN1 SIRT6 GNA12 POLR1B TARBP2 MAPK8IP3 POLR1A EIF4G1 DNAJC14 E4F1 MPG RHPN1 SMPD4 ZMAT2 NDOR1 ALG1 TP53 LRSAM1 CELSR3 MON2 GDPGP1 ZNF341 KDM5B CHERP RANBP3 SNRPC PPIA TBL3 DCDC1 TTC9C PTOV1 RHPN1-AS1 FBXO45 RFT1 MRPL20 PWP1 ZSCAN20 RAD1 E2F7 TAX1BP1 NAT10 COX6B1 THAP3 PIAS4 TK2 TRUB2 RCBTB1 LINC00888 DDX41 MTG2 BRIX1 MZF1 MSANTD4 MAP2K2 PRKAG1 SNAP25 LMBRD2 PCGF6 FAM86C2P SLC33A1 CSTF1 ZNF630 DNAL4 RTN4IP1 EIF2D ZNF740 LASP1 NOS3 MORN4 POLRMT PDXP MED16 DNAAF1 LUC7L3 DHDDS DGUOK MAP3K12 MAN2C1 SPHK2 TOP3A VPS16 MED15 C7orf25 RAB40C RUSC1 TRAFD1 NELFB EIF2B1 PARL DSN1 MST1 CDK11B TMEM259 RPL36 NOXA1 NUDT22 SRI PPP2R5E ZNF276 ZNF514 ZNF688 SDHAF1 NFE2L1 GGA1 OPA1 ZNF579 AP2B1 TMEM9 BAK1 TMPO TOMM40 TM9SF1 CTU2 SRFBP1 MRPL45P2 IMP4 MTMR4 GCC1 DCLRE1B TEFM ZNF425 URB2 ZNF638 AK9 GAK ARFIP2 TMEM167A ABCD3 AP1B1 SLC27A5 TTPAL DGKZ TRIM59 CACTIN IMP3 FNTA CS ZNF524 AP2A1 CCDC86 TMEM144 PLOD3 TMEM175 TAOK2 SPRYD4 C1orf74 ELP6 UVSSA E2F4 PPP2R1A ZC3H18 SLC35B4 TMEM219 DHX38 GORAB COX6A1 B3GALT6 METTL17 EVI5L NUP214 SLC44A1 C15orf40 EPS15L1 CCDC124 GRHPR PACRG PTPN23 COQ4 COPS7A ZNF839 ZNF664 METTL9	up	*
MIR548AH_3P_MIR548AM_3P	0.0011920	0.0184533	0.4550599	-0.2022279	-1.235652	680	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C RAB3C FYN CCL3L1 QKI GTF2I DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ZEB2 ARHGAP29 CNST STARD4 MCTP1 HBEGF TM2D3 ADAM17 ACOT2 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L PPP3CA TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FBXO8 FLI1 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 AFF1 BACE1 CNOT6L LIN7A STK24 USP25 SERTAD2 UFM1 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM YBX1 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 CPEB4 KCTD12 ETS1 MED30 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS PELI1 AGPS CDK17 YTHDF3 PKD2 NAPG MAPK8 BTBD7 ING3 MME AZIN1 DCK SERPINB1 PDS5B ABHD13 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 VPS4B CYP2U1 ARL14EP UBE2D1 ZDHHC21 SSH2 SOAT1 KPNA4 RBMS3 SCAI PAK2 SKI CECR2 FAM126B MMD CAMSAP2 C21orf91 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	*
GTGCCTT_MIR506	0.0029659	0.0349648	0.4317077	-0.2029839	-1.233470	615	RAB11FIP1 SEMA6A ABHD5 EDNRB TAL1 OSBPL11 KLF13 ADCY9 CLDND1 EGR2 DDX6 CAV1 MYADM THAP2 QKI CTDSP1 NR3C1 TSHZ1 CBL USP47 MOB1B GGA2 DNAJB14 LRRFIP2 EDEM1 SEMA6D SLC44A2 SH2B3 NFIX TTL PCYOX1 CYB5A BTG2 ZDHHC2 FZD4 SPIRE1 CAMTA1 NR4A1 FAM122A ITSN2 TFRC PTPN12 TLE4 LRRC57 DENND6A ZCCHC24 FAM76A ADAMTS9 CEBPA SOCS5 GAPVD1 MYRIP ABCC4 ATL3 MGAT4A MARVELD1 CADM1 SIK2 VIM C9orf72 SHC4 CCND2 ELK3 WDR48 ZMPSTE24 ELMSAN1 N4BP1 PAFAH1B1 KPNA3 GNAI2 FAM76B RSRC2 C2orf69 SERTAD2 KANK1 CREBRF FMNL2 VAMP3 SCN4B TMOD1 PDIK1L NSMAF SGK1 PSEN1 RNF141 ARL5B MITF VAT1 HIC1 PDE5A DNASE2 RHOG RCAN1 WTAP PI4K2B GRB2 THUMPD1 GRASP RPS6KA1 FSD1L SLC10A7 FAM177A1 FSTL3 GFPT2 NDST1 PPM1F BLOC1S6 CD151 POGLUT1 GRSF1 ADNP2 PNPLA2 CD164 HIVEP2 YTHDF3 SRSF6 TRAPPC10 NAP1L5 BTBD7 TFEB AP1G1 DCAF5 VAMP4 TSC22D1 ZBTB11 GNAI1 PIM1 ORC2 PHF19 GATA6 SPOCK2 PDE4B RXRA PITPNA VPS4B TBC1D1 BRWD1 EPHA2 G3BP2 TMEM184B SSH2 GRIN3A KPNA4 TMEM109 DAPK1 NPAT LIMCH1 STK4 BCAT1 SKI ANXA11 NRP2 NR3C2 NAA15 IQGAP1 WDFY3 SPOPL EVI5 PAPSS2 FNBP1 PLAG1 CHP1 CHIC2 SPPL2A SVIL HIPK1 CLOCK MYH10 ITGB1 CMPK1 RB1CC1 ALG2	down	*
ZNF407_TARGET_GENES	0.0015818	0.0227674	0.4550599	0.2386077	1.229939	1547	CPS1 PRR15 FOXM1 FOXA3 DDX12P LAD1 DNAH2 LYSMD1 CECR7 RPGRIP1L S100A2 ZNF84 COIL IGF2BP3 C17orf75 HOXB6 GBAP1 PDCD2L PSPH PBK SLC2A1 NUDCD3 TSFM DEPDC1 FANK1 MRPL46 METTL1 CCDC74A GINS1 EFNA3 CDK4 RACGAP1 ANKZF1 CABIN1 LRRC37A3 DBF4B NAALADL2 EIF2B5 FLAD1 AP1S1 NUF2 CENPA GPI TMEM254-AS1 CDC6 STC2 GOLGB1 KNOP1 HOXB7 LSR XPNPEP1 EIF3B DTL CCT6A MCM8 PIP4K2C MIS18A KIF27 B4GALT4 MRPS35 CDK5RAP3 LRRC27 COX11 SPDL1 SYT12 NME1 MANSC1 WDR62 ASAH2B ITGA2 POLR3A BZW2 CCDC150 C1orf220 NDUFB8 EXO1 CISD1 STRA6 CHAF1A BBS1 RPAP1 ZFYVE27 C9orf116 CUL9 QTRT1 KNTC1 RHNO1 TSGA10 CCDC13 CCT5 CENPL EME1 NUP155 WDR3 VANGL1 C20orf96 SAE1 ATR TPR KLHL25 SMARCAL1 COASY RGL1 SETDB1 ZNHIT6 PKM ENTPD6 MRPL27 PASK BLOC1S1 ZNF226 CDC25C ANG NME5 PPP1R35 MORC2 ZNHIT1 CHEK1 GET4 THYN1 MAD2L1 KIF3C PFKP ABCB9 TIMM50 KCNJ11 MRPS11 BRIP1 OGFOD2 IPO9 FNTB REPIN1 LRRIQ1 COMMD4 FADS2 SYMPK RNASEH2B-AS1 C2CD3 FBXO16 ARL16 ALDOA NIPAL1 STXBP4 MGAT4B SRRM5 TULP3 CNPY2 DYRK2 PSRC1 FGGY CKS1B FAHD2A SUPT5H URI1 LRRC6 PABPN1 HDGF CDK12 DIDO1 MDH1B FAM135A ARPC1A PICK1 CCT3 PLCH1 XRRA1 KIAA0753 PHF12 RAPGEFL1 GOLGA8A DIS3L2 POC5 PGBD2 PSMB5 MRPS2 MRPL17 PMEL DHX33 TRIM41 ENPP3 ZNF789 KRBA1 FEN1 POLR1C ZNF775 TMEM79 TNPO2 TTC23L LINC00649 THAP8 USP42 PLCG1 TRAF5 MTBP ATAD3A PBLD UCKL1 TMEM231 RTCB C9orf43 FGFR1OP PA2G4 EIF6 RANGAP1 CHCHD3 TPD52L2 EFTUD2 ELMOD3 G6PC3 CEP63 UBFD1 CAPS2 INTS7 ILF2 BBS5 CCDC142 NPHP1 DPP3 EXOC7 GNPAT SATB2 SMG5 C19orf47 FAH COA3 DHX40 PSMA5 PUS1 ZNF133 SNRPA AARSD1 RAD9A UROS YIPF3 GALNS CCDC151 PLEKHG3 COG7 KIF22 RAD51D SUDS3 DUSP12 UBE2Q1 PPOX DTYMK C1orf131 NFATC4 AKAP8L SOX2-OT OS9 GEMIN5 ACAD10 LAMTOR2 SPA17 ZSWIM1 PRMT7 SLC4A2 DNMBP SYNGAP1 C12orf73 CCDC159 POLB ATAD5 PPME1 COPS6 DNAJB13 NAT9 NIF3L1 SLX4IP RAD50 SASS6 CLDN12 EPN1 TADA3 EP400 UBQLN4 SUPT16H FN3KRP TIMM13 L3MBTL2 PWWP2A CDC20 TMEM106B AHCYL1 NPRL3 AAAS FBXO22 POP7 FAHD1 ZNF76 PPP6R1 POLR2J FITM2 NOL6 SRRT ABCA7 CDK5RAP2 ODF2L ZNF320 MGME1 MRPS33 ANKIB1 C16orf58 GID8 METTL2B WDR83 RPL7L1 RAI14 LPCAT4 CENPT ZSWIM8 NSUN6 PIGU KPTN HEATR1 DDX23 DYNC2H1 FAM161A LANCL2 CLUH SLC35A3 SCYL3 SRSF1 HAX1 RAB3D ZNF599 LRCH4 EFHB ZBTB9 PIP5K1A NEURL4 POLR2I POLR3E RHOBTB1 HAUS4 TMEM254 AP4B1 SMARCC2 LRRC46 SF3A2 STK35 TCHP CEP152 MST1P2 DUS2 KLHL7 NUP62 LRRC14 ZNF580 NME1-NME2 B9D1 LHX4 MCRS1 RPS26 MAP3K14 TSC2 ULK4 NTMT1 PRR11 TMC5 GABPB1-AS1 GTF3C2 DDX54 SCNM1 RNF121 DOHH USP39 TTC31 PRPF31 CLUAP1 VPS33B INO80E HOOK2 PRSS22 RAD51 TRAPPC9 CAPN10 STK25 ZNF384 MTIF3 ZNF292 RNF123 FBXW11 ST20 COPA ARHGAP11A MLLT1 RPRD2 FAM118B SNX8 AGBL5 PTPRF TBCB UBAP2L ALKBH6 UQCRQ OSGEP SMC2 BCL6 MAPK8IP3 CENPE EIF4G1 ZNF793 ANKMY2 EARS2 MPG ALG1 GGCX PRPF3 HGS CHERP TSNARE1 APEX1 MRPS27 SLC36A1 SNRPC TTC30B SIAE FAM78B CDKAL1 NELFA SFXN5 RAD1 SPATA20 PI4KB NAT10 RABL6 PIAS4 CLASP1 TRUB2 ILVBL LINC00888 ATG4B PTPN13 COL16A1 ACAD8 DDX41 BRIX1 TRPC4AP C12orf10	up	*
MIR548J_3P	0.0030061	0.0350491	0.4317077	-0.2010435	-1.226117	682	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C RAB3C FYN CCL3L1 QKI GTF2I DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ZEB2 ARHGAP29 CNST STARD4 ASAP1 MCTP1 HBEGF TM2D3 ADAM17 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L PPP3CA TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FLI1 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 AFF1 BACE1 CNOT6L LIN7A STK24 USP25 SERTAD2 UFM1 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM YBX1 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 CPEB4 KCTD12 ETS1 MED30 OSTM1 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS PELI1 AGPS CDK17 YTHDF3 PKD2 NAPG MAPK8 BTBD7 ING3 MME AZIN1 DCK SERPINB1 PDS5B ABHD13 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 VPS4B CYP2U1 ARL14EP UBE2D1 ZDHHC21 SSH2 SOAT1 KPNA4 RBMS3 SCAI PAK2 SKI CECR2 FAM126B MMD CAMSAP2 C21orf91 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	*
MIR4698	0.0043802	0.0448970	0.4070179	-0.2048093	-1.224403	533	RTKN2 COL25A1 SECISBP2L CPEB2 KL ARRDC4 OTUD1 CCDC88A SEC22C CALCRL QKI CDH13 ADRA1D ZCCHC2 MTMR10 KCNN3 NEDD9 TSHZ1 TET2 ASAP1 C1orf21 BZW1 SERINC1 NLK FZD4 REV3L CAV2 PAG1 STOM FOXJ3 SRSF2 SPTBN1 ANKRD29 EPM2AIP1 UBE2D3 TMEM38B KDSR MSR1 SNAI1 RAB12 PTPN21 FOXO1 SGTB SORBS1 LIN7C UHRF1BP1L OSTF1 GRK5 CLIC4 NPR3 KIF26A UBQLN1 UBE2E2 TEF CAPZA2 CCSER2 ELMSAN1 GCA MBD2 PPP2R5C KIAA0408 PAFAH1B1 FAM76B HSDL2 CNOT6L LIN7A ACTR2 STK24 LIN54 CLN8 SNX3 MOB4 MYLIP CDC40 PHTF2 APPL1 PLEKHA3 UTRN HMBOX1 CPEB4 CUL4A JPH1 ELOVL7 SP3 PABPC4 PI4K2B FRYL CREB1 COBLL1 RC3H1 FSD1L RBM22 PREX2 RASSF2 EPC2 CELF2 BLOC1S6 CTTNBP2 PELI1 CDK17 PTP4A1 MAPK8 NAP1L5 TCF4 PDS5B YTHDF2 SKIDA1 ZBTB11 NAB1 MAP3K2 MACF1 MBNL1 ATAD2B ARPP19 AMD1 NEK1 PDLIM5 CTTNBP2NL TFPI CDC42EP3 TPT1 SLC25A20 TAB2 USH2A PSME4 G3BP2 SSH2 KPNA4 RBMS3 PLGRKT HNRNPC LIMCH1 RASSF8 TTC28 ACADM SCAI RORA NDUFAF5 DNAJA2 SPATA13 ZBTB44 GPALPP1 MAP4 ACVR1C CDC14A GHR SAP18 TMEM30A SVIL HIPK1 ATF2 UBA6 CLOCK SLC38A2 KCNJ1 CSNK1G3 PRTG XPO7 C6orf62 UBE2W FAM160B1 SGIP1 UTS2B KIDINS220 AKAP12 TSC22D2 HMGB1 ARHGEF12 CUL2 CRIPT DR1	down	*
MIR548AE_3P_MIR548AQ_3P	0.0048009	0.0485428	0.4070179	-0.1985495	-1.215555	684	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C RAB3C FYN CCL3L1 QKI GTF2I DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ZEB2 ARHGAP29 CNST STARD4 MCTP1 HBEGF TM2D3 ADAM17 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L PPP3CA TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FLI1 SLC7A2 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 AFF1 BACE1 CNOT6L LIN7A STK24 USP25 SERTAD2 UFM1 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM YBX1 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 CPEB4 KCTD12 ETS1 MED30 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS PELI1 AGPS CDK17 YTHDF3 PKD2 NAPG MAPK8 BTBD7 ING3 MME AZIN1 DCK SERPINB1 PDS5B ABHD13 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 VPS4B CYP2U1 ARL14EP UBE2D1 ZDHHC21 SSH2 SOAT1 KPNA4 RBMS3 SCAI PAK2 SKI CECR2 FAM126B MMD CAMSAP2 C21orf91 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	*
CHAF1B_TARGET_GENES	0.0049552	0.0498070	0.4070179	-0.1924154	-1.187576	739	POLR3H RAB11FIP1 ABHD5 KLF13 LTA4H PHYHIP F2RL3 SNORD101 ALG1L13P IBA57 CCDC88A MED4 WDR74 BACH1 BAIAP2 QKI SRSF7 KCNN3 NR3C1 PDE4C TET2 EOGT TGFBR2 ACER3 SNORD12C TMX4 DNAJB14 PDE2A SNHG5 TXNIP SIGLEC6 ZBTB4 MCTP1 SLC36A4 MALAT1 RILP RNF139-AS1 EIF1 MAP3K8 PARVG LITAF REV3L NMUR1 ANPEP KLF6 BFAR PPP2R2A FOXJ3 TOR1AIP1 TMEM123 SRSF2 NFE2L2 UBE2D3 TFRC TOB1-AS1 RAB14 SNHG1 SORBS3 TIPARP CFD SNAI1 TIMM10B RNU11 PLAUR VASP RNU12 CEBPA VRK2 KLF7 CDKN1A COTL1 ELAC1 ID2 UXS1 CEP57 UBE2B EPS15 DUSP1 MFSD11 CCDC59 CARS2 PPP2R5C ZNF706 CALM2 DEGS1 AFF1 FAM76B RSRC2 AFF3 TDRD7 ST6GALNAC6 SACM1L ZNF426 ZCWPW1 TRAF3IP2-AS1 DDX60L RNF149 BCAR3 NSMAF MAML2 SEC14L1 NXF1 PPA2 NOTCH1 CUL4A RAC2 SNHG8 MAP4K4 JUNB FOXN2 EPC1 PPP1R15A RAPGEF1 PABPC4 LRRC37A15P IRF8 UBAC2 DDX5 RC3H1 MFAP4 AP3B1 DLEU2 YWHAZ TAGLN2 PXK RNVU1-14 PLCG2 SLC3A2 UBB CALM1 MBP DDX18 TFEB AKIRIN2 TCF4 CHRAC1 RNU2-63P SERPINB1 ZFAS1 SBF2 TMEM230 CBFA2T3 KCNN2 IRS2 EWSR1 C8orf37 PHF11 SNORA57 TOB1 RNU5D-1 WHAMMP2 AMD1 JUND ICAM1 INTS6 ZNF143 WDR1 RNU5B-1 IER5 CXCR4 LRP12 EXD3 RIPK2 TOB2 NSUN4 ARL14EP ACTB BRWD1 C17orf49 PKNOX2 NFKBIA PTEN LTBP3 RNU5F-1 TNFSF9 NABP1 PSMD9 RPL18P10 ZFAND2A EIF4A2 ATF4 MIS18BP1 TNFRSF10D PIEZO1 EIF4G2 DCUN1D2 GPN2 VPS13D HERPUD1 EGR1 USP4 SAP18 DUSP6 SPPL2A LNPEP FUS ING1 GAS5 TGOLN2 FTL SLC38A2	down	*
NAB2_TARGET_GENES	0.0022257	0.0287339	0.4317077	-0.1844883	-1.152301	1218	TM4SF19 ARHGAP31-AS1 LPIN2 USP12 KLF13 PPARG HVCN1 OSBPL1A HHEX RN7SL254P PTP4A2 STK24-AS1 PTPRE CLDND1 HSD17B6 LRRFIP1 RCOR1 TMEM170B LYL1 OTUD1 SH2D3C KLHL8 PLEKHF2 SEC22C DNAJC27-AS1 RASAL2 CORO1C MYADM NEDD4L BAIAP2 GTF2E2 THAP2 BMPR2 CTDSP1 STX11 KBTBD3 NR3C1 SPATA1 VAPA WBP4 OTUD4 LAMP1 EOGT FAR1-IT1 TRIB1 RFTN1 HSPG2 SNORD12C CASP9 LYRM4 AVPI1 NUMB EDEM1 ATP2B1 STARD9 RRAGC B3GNT5 SLC36A4 SGMS2 TTL ADAM17 LMNA GM2A BZW1 LINC01010 BTG2 PBX3 PICALM UBAC2-AS1 KLF10 FOXP1 ZNF410 KLF6 CAMTA1 ABHD6 FOXJ3 RNA5SP155 RGCC TMEM123 NFE2L2 SPRY2 PPP1R13B SETD3 PDGFA CCNI SLC7A2 EIF1B CFD CSRNP1 SNAI1 SYNPO NRARP ITPRIP TLE4 AHNAK DGKE SRSF5 EPOR BNIP2 LIMS1 ZSWIM6 TCP11L2 YBX3 PLAUR ZCCHC24 ITM2B REST PRKD3 DRAM1 VASP CEBPA CDK9 SOCS5 ITPK1 FMNL3 NCR3LG1 TPTEP1 NR1D2 C9orf72 ARHGEF26 CYP20A1 GSDMA KDM4A-AS1 CEP57 EPS15 CCSER2 PER1 CCDC59 WDR48 MBD2 N4BP2L1 DSE PPP2R5C DSTN SLC25A32 PPP2R5A MPC1 GNAQ GPR157 MAFF DEGS1 PLCD1 FAM76B MOB3A CPLX1 CDKN2AIP PIAS1 STK24 TDRD7 ST6GALNAC6 SRF BTG1 USP25 NINJ1 RPS6KA2 SERTAD2 ZCWPW1 ZNF330 RBM39 RBPJ CREBRF PRKRA SLC25A25 METAP1 CCNY ELF1 DNAJC27 TRAM2-AS1 PKNOX1 BCAR3 SGK1 APPL1 PLEKHA3 RAB8B SLC35E4 ETV3 NOTCH1 C20orf194 GABPA GLUD1 HIC1 MAP4K4 RHOG GSTO1 PODXL FBXO11 SKIL EEA1 SP3 PIK3R1 CD83 UBAC2 LYRM1 PCGF5 N4BP3 PTGER2 MALT1 RASAL2-AS1 RAB8A REL GTDC1 ZNRF3 RNF24 DLEU2 APH1B DENND4A PANK2 IP6K1 NDUFV2 CDK14 BTBD6 CDK17 CALM1 CD164 ECI2 MAPK8 DAGLA UBXN2A NUP153 TGFB1 TFEB AKIRIN2 TCF4 STRN CHRAC1 ZBTB1 ZFAS1 TGIF1 FAM228B YTHDF2 DUSP5 NAB1 MIA3 ZC3H12D IRS2 NFYC GNG5 PHF19 APLP2 NQO2 BAG6 MACF1 PLEKHO2 PLA2G15 ETS2 ATAD2B RXRA HACE1 RNF2 BMP2K ARAP2 MIER1 YAF2 WDR1 SF1 ZNF438 TPT1 ATP9B HSP90AA1 EXD3 TRAPPC8 ZBTB25 METTL21A CYP2U1 HSPA8 TBC1D1 DDX59 BRWD1 TRAF1 MBD5 PALD1 LYSMD3 FDX1 ING2 CUL3 RASSF8 ACADM RNF38 SCAI SKI CHCHD7 THRAP3 SNAP29 CAMSAP2 C21orf91 CCND3 GSPT1 TLK1 RNH1 SPOPL PURB ARFGAP3 MAN1C1 HSDL1 SMPD1 INTS10 SPHK1 DCUN1D2 RABGEF1 ARRDC2 IRF2 CBX7 AFTPH	down	*

C4 cancer Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
GNF2_CASP1	0.0000000	0.0000000	1.0476265	-0.6159634	-2.990242	94	FCN1 PECAM1 MNDA HSD17B11 CD44 SAMHD1 MYD88 STX11 NCF2 IGSF6 PILRA LILRB3 FGR IER2 DPEP2 CD33 NAAA CSGALNACT2 MCL1 FBXL5 EVI2B PPT1 CASP1 BST1 CPVL PLBD1 COTL1 SELL CD302 FCER1G DUSP1 EVI2A FKBP15 CMTM6 HCK CTSS HK3 TYROBP JUNB RHOG IFNGR1 GMFG CD1D CD86 CCR1 RGS2 ARRB2 ACAP2 S100A4 THEMIS2 DAZAP2 IQGAP1	down	***
GNF2_HCK	0.0000000	0.0000000	0.9759947	-0.6315769	-2.978985	80	FCN1 PECAM1 MNDA HSD17B11 C5AR1 STX11 NCF2 FRAT1 IGSF6 PILRA LILRB3 FGR DPEP2 SLC7A7 CLEC7A CD93 SPI1 MCL1 FBXL5 EVI2B PPT1 SDCBP CASP1 BST1 CPVL PLBD1 LY96 COTL1 ITGAX CD302 FCER1G EVI2A CMTM6 HCK CTSS HK3 TYROBP TREM1 RHOG IFNGR1	down	***
GNF2_MCL1	0.0000000	0.0000000	0.8870750	-0.6973667	-2.921231	47	RAB11FIP1 PECAM1 MNDA PTPRE HSD17B11 SAMHD1 MYD88 STX11 NCF2 IGSF6 IER2 DPEP2 CSGALNACT2 MCL1 FBXL5 EVI2B PPT1 CASP1 SELL CD302 CMTM6 HCK CTSS JUNB IFNGR1 CCR1 RGS2 ARRB2 ACAP2 S100A4 THEMIS2 DAZAP2	down	***
GNF2_CCNA2	0.0000000	0.0000000	1.0864405	0.7378206	2.849953	63	FOXM1 KIF20A HJURP FANCI BUB1B CENPF KIF18B NDC80 TTK RACGAP1 E2F8 KIF14 ASPM PLK1 CDCA8 AURKB CENPA ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 NCAPD2 ZWINT MELK HMMR MKI67 TOP2A AURKA MCM7 RRM2 KIF11 MCM3 RAD51AP1 CKS1B NUSAP1 ASF1B CDK1 BIRC5 GMNN NCAPG FEN1 EZH2	up	***
MODULE_54	0.0000000	0.0000000	1.4245627	0.6111485	2.827156	224	TRIP13 PLAT DDX11 FOXM1 HJURP CDC45 ELOVL6 TROAP BUB1B NEK2 CCNB1 CENPF TIMELESS POLQ UBE2T PSPH PBK NDC80 DEPDC1 DEPDC1B CDCA7 TTK GINS1 CDK4 E2F8 KIF14 ANLN ASPM PLK1 NUF2 AURKB CENPA PTTG1 ECT2 CDC6 TPX2 CCNB2 CMYA5 MCM4 MCM2 TYMS MYBL2 ORC1 CCNF HBB CCT6A SRPK1 NCAPD2 ZWINT SCG5 NME1 RANBP1 ITGA2 MELK HMMR NUDT1 KIF23 CEP55 CHAF1A MKI67 KNTC1 RHNO1 BUB1 TOP2A CCT5 AURKA KIF2C MCM7 RRM2 CDCA5 RAD54L KIF11 GPSM2 MCM3 CHAF1B LMNB1 CDC25C AIMP2 TOPBP1 CHEK1 MAD2L1 AHCY PFKP PKMYT1 BLM PSRC1 KNSTRN CKS1B CDKN2C NUSAP1 TMEM106C MB ASF1B CDK1 POLE2 BIRC5 GMNN E2F1 UNG NEIL3 FEN1 SPAG5 SNRPE RECQL4 LAPTM4B TRIM24 DLGAP5 AMPH TACC3 LMNB2 MAPK13 DTYMK GINS2 ANP32E AGPAT5 POLD1 CDC7 CDC20 KIAA0100 HMGA1 MCM6 CKAP2 MCM5 LRRC17 RCC1 NT5DC2 GAD1 ATAD2 MSH2 CCNA2 PRIM1 CDH1 PRR11 SHCBP1 RFC5 RAD51 ZWILCH ARHGAP11A	up	***
GNF2_CDC20	0.0000000	0.0000000	0.9969862	0.7440967	2.771052	51	FOXM1 KIF20A BUB1B CENPF KIF18B NDC80 TTK RACGAP1 ASPM PLK1 CDCA8 AURKB PTTG1 ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT MELK HMMR MKI67 BUB1 TOP2A AURKA KIF2C RRM2 KIF11 CKS1B NUSAP1 CDK1 BIRC5 GMNN SPAG5	up	***
GNF2_BUB1B	0.0000000	0.0000000	0.9969862	0.7501970	2.770425	49	HELLS KIF20A HJURP FANCI BUB1B NDC80 TTK GINS1 RACGAP1 KIF14 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS NCAPD2 ZWINT MELK HMMR CEP55 BUB1 TOP2A AURKA RRM2 KIF11 MCM3 LMNB1 ASF1B GMNN NUP205 SPAG5 PA2G4	up	***
MODULE_5	0.0000000	0.0000000	1.4462029	-0.4709417	-2.752307	384	EPAS1 SLPI ACP5 CD52 HMOX1 FCN1 TEK DLC1 PECAM1 CD55 GATA2 PGC IL1B FABP4 MNDA CLEC3B FBP1 CYP27A1 LPXN EMP2 CYP4B1 LIPA RAMP2 CDH5 INSIG1 ENG FOLR1 LPL CD44 LMO2 PPP4R1 LDB2 CAV1 CITED2 CALCRL SLC39A8 MAL ALAS1 MARCO TGFBR3 MSLN NEDD9 IL1RN FUCA1 EPB41L3 TGFBR2 LILRB3 RFTN1 HSPG2 FGR HEG1 APOD ANXA1 TBX2 SLC7A7 CACNA2D2 ASAH1 CSRP1 CYB5A MALL RNASE1 CAV2 PTX3 LCP1 LAIR1 NR4A1 GRN CES1 SRGN APOC1 CD37 RHOB PTPN12 MAP2K3 CFD BIRC2 AOC3 PLAUR DAB2 THBS1 CLDN5 GRK5 MYO1B CCL3 LAPTM5 CDKN1A CADM1 RBMS1 PTPRC CXCL2 AQP4 SELL HOPX CD302 SFTPD CD53 FCER1G PER1 ALOX5AP ADIPOR2 WFS1 VAMP5 IL7R MYH11 HLA-DQA1 HES1 MAFF ANXA3 CRIM1 VWF ARHGDIB HCK EMP3 IL6 SOCS3 SLCO2B1 AQP3 LAMB2 CYB5R1 RAB31 LTBP2 SFTPB RAC2 ST6GALNAC4 JUNB ATP11A RHOG IFNGR1 PPP1R15A GMFG MFAP4 SNX1 RPS6KA1 FSTL3 GPRC5A CST7 SNRK FGFR4 CD34 ACSL1 CD151 RRAS MSMO1 NKG7 TIMP2 TGFB1 SFTPC SERPINB1 LRRC32 PCDH17 PIM1 ORM2 CCR1 FCGRT RGS2 CLEC2B ETS2 SOD3 ICAM1 GPX3	down	***
GNF2_PCNA	0.0000000	0.0000000	1.0073180	0.7085173	2.747887	64	FOXM1 FANCI BUB1B CENPF KIF18B NDC80 TTK GINS1 RACGAP1 ASPM CDCA8 ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 PRC1 DTL ZWINT MELK HMMR MKI67 KIF15 TOP2A AURKA MCM7 RRM2 RAD54L KIF11 MCM3 DNAJC9 RAD51AP1 NUSAP1 CDK1 POLE2 BIRC5 GMNN FEN1 PA2G4 DLGAP5 GINS2 CDC20 MCM6 MCM5 MSH2 CCNA2 PRIM1 SHCBP1 PAXIP1 SMC2 CENPE	up	***
GNF2_TNFRSF1B	0.0000000	0.0000000	0.8266573	-0.6323857	-2.729842	52	FCN1 PECAM1 HSD17B11 MYD88 NCF2 IGSF6 PILRA LILRB3 FGR DPEP2 SLC7A7 PPT1 CASP1 CPVL COTL1 FCER1G DUSP1 CMTM6 HCK CTSS TYROBP RHOG CD1D DOK2 CCR1 RGS2 ARRB2 S100A4 THEMIS2 SH3BGRL3 AOAH	down	***
GNF2_MCM4	0.0000000	0.0000000	0.9653278	0.7284834	2.717100	52	FOXM1 HELLS FANCI BUB1B KIF18B NDC80 TTK GINS1 RACGAP1 KIF14 ASPM CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS ZWINT MELK HMMR BUB1 TOP2A AURKA MCM7 RRM2 KIF11 MCM3 LMNB1 MAD2L1 RAD51AP1 ASF1B GMNN FEN1 PA2G4 GINS2 POLD1 CDC20 CENPM MCM6 MCM5	up	***
GNF2_RRM2	0.0000000	0.0000000	0.8986712	0.7605426	2.660707	38	FOXM1 BUB1B CENPF KIF18B NDC80 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS ZWINT MELK HMMR MKI67 BUB1 TOP2A AURKA RRM2 KIF11 MCM3 LMNB1 NUSAP1 CDK1 BIRC5 GMNN DLGAP5 CDC20 CENPM MCM6	up	***
GNF2_TTK	0.0000000	0.0000000	0.8870750	0.7581135	2.652209	38	FOXM1 HJURP FANCI BUB1B CENPF KIF18B NDC80 TTK RACGAP1 ASPM TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT CCT2 MELK HMMR TOP2A KIF2C KIF11 NUSAP1 CDK1 GMNN FEN1	up	***
GNF2_BUB1	0.0000000	0.0000000	0.8753251	0.8175272	2.649872	26	FOXM1 KIF20A BUB1B NDC80 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 CDT1 RANBP1 MELK HMMR BUB1 KIF2C RRM2 CHAF1B CKS1B ASF1B GMNN SPAG5	up	***
GNF2_ITGB2	0.0000000	0.0000002	0.7614608	-0.6322732	-2.648557	47	PECAM1 HSD17B11 MYD88 FGR DPEP2 MCL1 FBXL5 CASP1 OSTF1 ITGAX FCER1G CMTM6 HCK TYROBP RHOG PTGER4 GMFG BIN2 DOK2 RGS2 SELPLG ARRB2 ACAP2 S100A4 ICAM3 THEMIS2 IQGAP1 SH3BGRL3 AOAH IRF1 PLCB2 MYO1F APOBR TNFRSF1B PYCARD IL10RA TMEM127 HCLS1	down	***
GNF2_CCNB2	0.0000000	0.0000000	0.9101197	0.7094783	2.646215	52	FOXM1 KIF20A BUB1B CENPF PBK KIF18B NDC80 TTK RACGAP1 ASPM CDCA8 PTTG1 ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT MELK HMMR BUB1 TOP2A AURKA KIF2C RRM2 KIF11 NUSAP1 CDK1 BIRC5 GMNN FEN1 SPAG5	up	***
GNF2_HMMR	0.0000000	0.0000000	0.8986712	0.7249135	2.637692	46	FOXM1 KIF20A BUB1B CENPF KIF18B NDC80 TTK E2F8 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT MELK HMMR MKI67 BUB1 TOP2A AURKA RRM2 KIF11 NUSAP1 CDK1 BIRC5 GMNN FEN1 DLGAP5 GINS2	up	***
GNF2_CDC2	0.0000000	0.0000000	0.9101197	0.6929047	2.632085	56	FOXM1 KIF20A HJURP FANCI CENPF KIF18B NDC80 TTK E2F8 ASPM CDCA8 PTTG1 TPX2 CCNB2 MCM2 TYMS MYBL2 PRC1 CCNF ZWINT MELK HMMR MKI67 KIF15 TOP2A AURKA RRM2 KIF11 DNAJC9 NUSAP1 CDK1 BIRC5 NCAPG FEN1 EZH2 DLGAP5 GINS2 CDC20 CKAP2 CCNA2 PRIM1 SHCBP1 SMC2 CENPE UBE2C	up	***
GNF2_CENPF	0.0000000	0.0000000	0.8986712	0.6925339	2.618818	55	FOXM1 HJURP MCM10 FANCI CENPF KIF18B NDC80 TTK E2F8 ASPM CDCA8 PTTG1 TPX2 CCNB2 MCM2 TYMS MYBL2 PRC1 CCNF ZWINT HMMR MKI67 KIF15 TOP2A AURKA MCM7 RRM2 KIF11 MCM3 DNAJC9 NUSAP1 CDK1 BIRC5 FEN1 DLGAP5 DTYMK GINS2 CDC20 CKAP2 CCNA2 PRIM1 SHCBP1 SMC2 CENPE UBE2C	up	***
GNF2_RRM1	0.0000000	0.0000000	0.9545416	0.6406699	2.605589	85	FOXM1 FANCI BUB1B CENPF KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 KIF14 ASPM CDCA8 AURKB CCNB2 MCM4 MCM2 TYMS PRC1 DTL CCT6A ZWINT MELK HMMR MKI67 PCCB TOP2A AURKA MCM7 RRM2 KIF11 MCM3 RAD51AP1 NUSAP1 CDK1 BIRC5 GMNN FEN1 PA2G4 CHCHD3 DLGAP5 SSRP1 DTYMK GINS2 ANP32E CDC20 CENPM MCM6 MCM5 SNRPD1 MSH2 CCNA2 PRIM1 SHCBP1 SMC2 CENPE PAICS UBE2C	up	***
GNF2_ESPL1	0.0000000	0.0000000	0.8390889	0.7474244	2.585839	35	FOXM1 KIF20A BUB1B ASPM PLK1 CDCA8 AURKB CENPA ESPL1 TPX2 CCNB2 MCM4 NCAPD2 MELK HMMR MKI67 BUB1 TOP2A KIF2C RRM2 KIF11 MAD2L1 CKS1B ASF1B BIRC5 SPAG5 CDC20 CENPM MCM6 CCNA2 SMC2 CENPE PAICS UBE2C	up	***
GNF2_MKI67	0.0000000	0.0000000	0.8012156	0.7823286	2.577454	27	FOXM1 KIF20A CENPF KIF18B ASPM CENPA ESPL1 TPX2 NCAPD2 ZWINT MELK HMMR MKI67 TOP2A AURKA RRM2 KIF11 NUSAP1 CDK1 BIRC5 NCAPG	up	***
GNF2_CARD15	0.0000000	0.0000002	0.7614608	-0.5874212	-2.574017	56	FCN1 PECAM1 MNDA STX11 NCF2 IGSF6 PILRA LILRB3 CD33 SLC7A7 CD93 MCL1 PPT1 CASP1 BST1 CPVL PLBD1 COTL1 CD302 DUSP1 HCK CTSS HK3 TYROBP FOS CD1D CD86 CCR1 RGS2	down	***
GNF2_PECAM1	0.0000000	0.0000009	0.7195128	-0.6240106	-2.568370	45	FCN1 PECAM1 HSD17B11 NCF2 IGSF6 LILRB3 CD93 MCL1 PPT1 CASP1 PLBD1 CD302 FCER1G DUSP1 CMTM6 HCK CTSS TYROBP IFNGR1 CCR1 RGS2 CEBPD S100A4 THEMIS2 SH3BGRL3 ZFP36 MFSD1 TNFRSF1B PYCARD TMEM127 FGL2 RNF130	down	***
GNF2_RFC4	0.0000000	0.0000000	0.8634154	0.6722172	2.563926	57	FOXM1 MCM10 FANCI CENPF TIMELESS NDC80 TTK GINS1 ASPM CCNB2 MCM4 MCM2 TYMS NCAPD2 ZWINT CCT2 RANBP1 KNTC1 TOP2A MCM7 RAD54L KIF11 MCM3 LIG1 RAD51AP1 CKS1B CDK1 BIRC5 GMNN FEN1 SNRPE SSRP1 GINS2 SUPT16H MCM6 SNRPD1 MSH2 CCNA2 PRIM1 RFC5 SMC2 PAICS UBE2C	up	***
GNF2_TNFSF10	0.0000003	0.0000051	0.6749629	-0.7080512	-2.552943	26	MNDA C5AR1 P2RY13 NCF2 IGSF6 PILRA DPEP2 CLEC7A SPI1 EVI2B SDCBP LY96 HCK CCR1 RGS2 ARRB2 UBE2D1 S100A4	down	***
GNF2_FEN1	0.0000000	0.0000000	0.8634154	0.6753089	2.544517	54	FOXM1 FANCI CENPF KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 CCNB2 MCM4 MCM2 TYMS PRC1 DTL ZWINT HMMR PCCB TOP2A MCM7 KIF11 MCM3 DNAJC9 RAD51AP1 NUSAP1 CDK1 POLE2 GMNN FEN1 DLGAP5 DTYMK GINS2 MCM5 SNRPD1 MSH2 CCNA2 SHCBP1 RFC5	up	***
GNF2_FOS	0.0000001	0.0000016	0.7049757	-0.6593366	-2.526693	33	FCN1 STX11 IER2 CD33 KLF4 CPVL TPP1 PLBD1 CD302 DUSP1 CTSS HK3 LGALS2 FOS CD1D NLRP3 SCPEP1 NFKBIA DUSP6 ZFP36 MFSD1 CPPED1 PYCARD CAPG FGL2 NAIP RNF130	down	***
GNF2_SPI1	0.0000004	0.0000059	0.6749629	-0.6755769	-2.526574	30	MNDA BACH1 AQP9 C5AR1 P2RY13 NCF2 FRAT1 IGSF6 PILRA CLEC7A SPI1 VASP LY96 GCA HCK	down	***
GNF2_CD1D	0.0000003	0.0000046	0.6749629	-0.6425331	-2.521100	36	FCN1 STX11 IGSF6 LILRB3 CD33 SLC7A7 CASP1 CPVL PLBD1 COTL1 CD302 DUSP1 HCK CTSS HK3 TYROBP FOS CD1D CD86 RGS2	down	***
GNF2_CD33	0.0000001	0.0000011	0.7049757	-0.6185805	-2.512811	42	FCN1 STX11 LILRB3 IER2 CD33 SLC7A7 IFI30 CD93 PPT1 CASP1 BST1 CPVL PLBD1 CD302 DUSP1 CTSS HK3 TYROBP LGALS2 FOS CD1D RGS2 NLRP3	down	***
GNF2_SMC4L1	0.0000000	0.0000000	0.8753251	0.6161906	2.484394	80	FOXM1 FANCI BUB1B CENPF KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 ASPM CDCA8 CCNB2 MCM4 MCM2 TYMS PRC1 DTL ZWINT HMMR PCCB TOP2A AURKA CBX3 MCM7 KIF11 MCM3 DNAJC9 RAD51AP1 NUSAP1 CDK1 POLE2 GMNN FEN1 DLGAP5 SSRP1 DTYMK GINS2 ANP32E SUPT16H CDC20 CKAP2 MCM5 SNRPD1 SRSF1 MSH2 CCNA2 PRIM1 SHCBP1 ZWILCH	up	***
GNF2_CENPE	0.0000000	0.0000000	0.7881868	0.7101751	2.483855	37	FOXM1 CENPF KIF18B NDC80 ASPM CDCA8 AURKB ESPL1 CCNB2 TYMS MYBL2 PRC1 CCNF ZWINT HMMR MKI67 BUB1 AURKA RRM2 KIF11 CKS1B NUSAP1 CDK1 BIRC5 DLGAP5 CDC20 CCNA2 PRIM1 SHCBP1 SMC2 CENPE UBE2C	up	***
GNF2_CKS2	0.0000000	0.0000001	0.7749390	0.6635735	2.444961	48	FOXM1 KIF20A FANCI CENPF NDC80 TTK GINS1 RACGAP1 ASPM PTTG1 CCNB2 MCM4 MCM2 TYMS PRC1 DTL ZWINT CCT2 HMMR TOP2A NUSAP1 CDK1 BIRC5 GMNN FEN1 DLGAP5 GINS2 CDC20 CKAP2 SNRPD1 CCNA2 SHCBP1 SMC2 CENPE	up	***
GNF2_CD7	0.0000014	0.0000179	0.6435518	-0.6227173	-2.434293	35	CTSW GIMAP6 CCL4 XCL2 PRF1 KLRD1 CD160 KLRB1 IL2RB PTGER2 CD7 TBX21 CST7 RUNX3 NKG7 IL18RAP KLRK1 RORA KLRF1 PRKCH ITGAL	down	***
GNF2_MYD88	0.0000001	0.0000022	0.6901325	-0.5665879	-2.430640	51	PTPRE MYD88 RHOA SH2B3 MAN2B1 MCL1 CASP1 OSTF1 SELL CD53 FCER1G FKBP15 CMTM6 ACTR2 TYROBP RAB8A RPS6KA1 CAP1 RGS2 SELPLG ARPC5 PAK2 THEMIS2 DAZAP2 IQGAP1 CYBA SH3BGRL3 SKAP2 TNFRSF1B PYCARD TMEM127 DOCK2 HCLS1 LSP1	down	***
GNF2_PTPN4	0.0000006	0.0000079	0.6594444	-0.5931467	-2.414525	43	GPR65 FYN CTSW GNPTAB CCL4 XCL2 PRF1 KLRD1 MATK CD160 KLRB1 IL2RB JAK1 PTGER2 CD7 TBX21 CST7 RUNX3 NKG7 IL18RAP KLRK1 RORA KLRF1 PRKCH ITGAL S1PR5	down	***
GNF2_S100A4	0.0000008	0.0000118	0.6594444	-0.6030222	-2.395849	39	FCN1 PECAM1 HSD17B11 NCF2 IGSF6 PILRA LILRB3 FGR DPEP2 MCL1 CASP1 CPVL COTL1 FCER1G HCK TYROBP DOK2 CCR1 RGS2 ARRB2 S100A4 THEMIS2 SH3BGRL3	down	***
GNF2_CKS1B	0.0000000	0.0000007	0.7195128	0.6895578	2.393585	36	TRIP13 KIF20A NDC80 GMPS ASPM CDCA8 AURKB ESPL1 TPX2 NCAPD2 RANBP1 MELK BUB1 KIF2C KIF11 MCM3 CKS1B ASF1B BIRC5 ATIC PA2G4 RNASEH2A CDC20 MCM6 CCNA2 SMC2 CENPE PAICS UBE2C	up	***
MORF_BUB1	0.0000000	0.0000004	0.7337620	0.6643178	2.382084	42	FOXM1 BUB1B CCNB1 NDC80 KIF14 PLK1 ESPL1 TPX2 SRPK1 XPOT ZWINT HMMR BUB1 CCT5 KIF2C KIF11 SSBP1 GOT2 PMEL SPAG5 VBP1 DLGAP5 TYRO3 MCM6 SRSF1	up	***
GNF2_SMC2L1	0.0000001	0.0000023	0.6901325	0.7005712	2.375369	32	FOXM1 CENPF KIF18B NDC80 TTK ASPM CDCA8 ESPL1 CCNB2 MYBL2 ZWINT HMMR BUB1 TOP2A KIF11 MCM3 CKS1B NUSAP1 CDK1 BIRC5 CDC20 MCM6 CCNA2 PRIM1 SMC2 CENPE	up	***
MODULE_397	0.0000000	0.0000000	0.8513391	0.5573580	2.364680	108	TRIP13 DDX11 FOXM1 CDC45 BUB1B EYA2 CENPF CIB2 NDC80 CABIN1 NOL12 IGFBP6 BAIAP2L1 PLK1 NUF2 PTTG1 TPX2 HOXB7 MYBL2 ORC1 GON4L SRPK1 NCAPD2 ZNF74 KIF23 AURKA FGG CDCA5 ANKEF1 KIF11 GPSM2 SALL2 ASF1B DNAH6 GMNN E2F1 TRAP1 NUP205 RAB6B FER1L4 IGSF3 GRAMD1A ARHGEF16 ALDH7A1 EFCAB2 SNRPA RAD51D JMJD4 NT5M CDC20 WDR34 RPUSD1 NOL6 ZNF432 PYGO2 CACNB3 TRIP6 GRAMD1B ARHGAP11A SMC2 BCAS3 CENPE CDC25B EPHB4 MRPS26 NCAPH F5	up	***
MODULE_158	0.0000000	0.0000008	0.7195128	0.6702414	2.364581	39	DDX11 CDC45 CENPF PRIM2 POLE ORC1 CHAF1A TOP2A POLD2 RRM2 MCM3 CHAF1B LIG1 TOPBP1 BLM SSBP1 POLE2 GMNN FEN1 RNASEH2A POLD1 CDC7 RPA1 MCM6 PRIM1 RFC5 CENPE	up	***
GNF2_STAT6	0.0000001	0.0000018	0.7049757	-0.5213206	-2.359374	64	LRRFIP1 MYD88 LCP1 EVI2B BNIP2 OSTF1 LAPTM5 SELL ACTR3 CD53 MBD2 CMTM6 ARHGDIB ACTR2 EMP3 SNAP23 CD48 RAC2 JUNB CAP1 MOB1A TGFB1 ADPGK ARPC2 ACAP2 ICAM3 ARPC5 PAK2 ANXA11 DAZAP2 IQGAP1 CYBA FXYD5 CAPZA1 SERP1	down	***
GNF2_RAB7L1	0.0000045	0.0000564	0.6105269	-0.6319362	-2.357525	29	GPR65 CTSW GNPTAB CCL4 PRF1 KLRD1 IL2RB JAK1 PTGER2 RUNX3 NKG7 BIN2 GSAP CYTH1 KLRF1 PRKCH TES CYTIP GZMA STK10	down	***
MODULE_125	0.0000001	0.0000019	0.7049757	0.6586616	2.347595	40	DDX11 CDC45 CENPF PRIM2 POLE ORC1 CHAF1A TOP2A POLD2 RRM2 MCM3 CHAF1B LIG1 TOPBP1 BLM SSBP1 POLE2 GMNN FEN1 RNASEH2A POLD1 CDC7 RPA1 MCM6 PRIM1 RFC5 CENPE	up	***
GNF2_H2AFX	0.0000002	0.0000029	0.6901325	0.7025633	2.340168	29	FOXM1 CENPF KIF18B ASPM CDCA8 PTTG1 CCNB2 MCM2 TYMS PRC1 CCNF ZWINT AURKA RRM2 DNAJC9 NUSAP1 CDK1 BIRC5 DLGAP5 CDC20 CCNA2 SHCBP1 CENPE	up	***
GNF2_CD14	0.0000114	0.0001307	0.5933255	-0.6226917	-2.328790	30	FCN1 STX11 LILRB3 CD33 SLC7A7 IFI30 CD93 PLBD1 CD302 DUSP1 HCK CTSS HK3 TYROBP CD1D RGS2	down	***
GNF2_FGR	0.0000104	0.0001208	0.5933255	-0.6414542	-2.328239	27	LILRB3 FGR IFI30 CASP1 COTL1 FCER1G CMTM6 HCK CTSS TYROBP RHOG RGS2 S100A4 THEMIS2 SH3BGRL3 AOAH TNFRSF1B PYCARD TMEM127 FGL2	down	***
MORF_BUB1B	0.0000000	0.0000008	0.7195128	0.6091616	2.295278	54	TRIP13 BUB1B NDC80 TTK KIF14 PLK1 CENPA ESPL1 TPX2 MCM2 SRPK1 SHMT2 ZWINT HMMR BUB1 TOP2A CCT5 PRKDC RAD54L ACTL6A CDKN2C CDK1 GOT2 DNMT1 ANP32E KIF20B TYRO3 CDC7 MCM6	up	***
MODULE_57	0.0000001	0.0000020	0.6901325	0.6081647	2.276037	53	CDC45 CHEK2 BUB1B CCNB1 CDK4 PLK1 PTTG1 ESPL1 CDC6 E2F3 CCNB2 MCM4 MCM2 CDC25A ORC1 BUB1 MCM7 MAD1L1 PRKDC MCM3 CDC25C CHEK1 MAD2L1 MDM2 PKMYT1 CDK1 E2F1 CCNE1 HDAC1 CDC7 CDC20 MCM6 MCM5	up	***
GNF2_IL2RB	0.0000123	0.0001369	0.5933255	-0.5795757	-2.242446	34	CTSW GNPTAB CCL4 XCL2 PRF1 KLRD1 MATK CD160 IL2RB PTGER2 CD7 TBX21 CST7 RUNX3 NKG7 IL18RAP KLRF1 CX3CR1 PRKCH S1PR5	down	***
GNF2_RFC3	0.0000009	0.0000124	0.6594444	0.6328671	2.232727	39	FOXM1 FANCI TIMELESS NDC80 ASPM MCM4 NCAPD2 RANBP1 HMMR TOP2A KIF11 MCM3 RAD51AP1 CKS1B CDK1 BIRC5 SSRP1 GINS2 SUPT16H PFAS MCM6 SNRPD1 CCNA2 SMC2 CENPE PAICS UBE2C ADSL MSH6 SMC4 CTPS1 MRPL35 RFC3 RFC4 ITGB3BP	up	***
MODULE_320	0.0000063	0.0000782	0.6105269	0.7712329	2.209304	16	DDX11 NDC80 BRCA1 TTK PTTG1 ESPL1 NCAPD2 KIF23 KIF11	up	***
MODULE_96	0.0000518	0.0004992	0.5573322	-0.6070706	-2.203440	27	FCN1 OLR1 ASGR1 FCN3 CLEC3B THBD CHIT1 CLEC10A CD22 SELL SELP SFTPD GFPT2 LGALS2 LGALS3 CLEC2B	down	***
MODULE_451	0.0000226	0.0002421	0.5756103	0.6508171	2.167180	28	CDC45 NEK2 CCNB1 MKS1 CDK4 PLK1 CENPA MYBL2 MELK MKI67 TOP2A RNFT2 TOPBP1 CDK1 ESRP1 SPATA9 FEN1	up	***
GNF2_SELL	0.0000319	0.0003262	0.5573322	-0.5315580	-2.163816	43	LRRFIP1 HSD17B11 MYD88 DPEP2 MCL1 EVI2B CASP1 LAPTM5 SELL CD53 CMTM6 ARHGDIB JUNB GMFG ARRB2 ACAP2 ICAM3 PAK2 THEMIS2 DAZAP2	down	***
MODULE_410	0.0001125	0.0010382	0.5384341	-0.5775181	-2.127429	28	FCN1 OLR1 ASGR1 CLEC3B THBD CHIT1 CLEC10A CD22 SELL SELP SFTPD GFPT2 LGALS2 LGALS3 CLEC2B	down	**
GCM_DDX5	0.0000352	0.0003558	0.5573322	-0.4816830	-2.120620	57	DYRK1A TRA2B SRSF2 HNRNPU HMGN1 SRSF5 TAF9 DNTTIP2 BCLAF1 AFF1 RABGGTB SLC25A3 ESD DDX5 TCP1 YWHAZ USP7 DDX18 HNRNPD NUP153 HNRNPA2B1 SRSF4 KHDRBS1 SF1 PSMD6 EIF4G2 HNRNPH1 FUS RB1CC1 RAD21 SRP14	down	***
GNF2_SERPINB5	0.0000220	0.0002390	0.5756103	0.6633524	2.119611	24	COL17A1 GPR87 TP63 KRT5 S100A2 FERMT1 LAMC2 PERP GJB3 CDH3 KRT19 AHNAK2 PTHLH FGFBP1 KRT17	up	***
MODULE_45	0.0000000	0.0000000	1.0574636	-0.3543772	-2.109025	461	SLPI SLC31A2 CD52 FCN1 ASGR1 PECAM1 CD55 SPN IL1B MNDA LPXN PTPRE CYP4B1 LIPA CD44 LY86 LMO2 AQP9 STX11 MAL MKNK1 BCL2A1 NCF2 IL1RN CD22 SLC11A1 TGFBR2 IGSF6 LILRB3 CD8A FGR HEG1 KCNAB1 ANXA1 MAN2B1 BMP1 SLC7A7 ASAH1 KCNK3 ITGA5 ANPEP SLC7A11 LCP1 LAIR1 GRN SLC19A1 SRGN SPI1 CD37 KRT4 SLC5A2 CD58 PPP3CC ZMIZ1 PTPN12 EVI2B MAP2K3 CFD STAT5A TBC1D9 GPA33 KIAA0513 CASP1 PTAFR CPVL FUT7 DENND3 LY96 GMPR LAPTM5 PTPRC SELL CD302 ARC PNRC1 CCND2 M6PR SFTPD CD53 PRF1 FCER1G ALOX5AP CD300C PLEK EVI2A N4BP2L1 SLC6A6 IL7R ARHGDIB HCK NINJ1 EMP3 KCNA5 CD8B ARL6IP5 S1PR4 HCAR3 METAP1 CTSS IL2RB OASL AQP3 CD48 STAT4 RAB31 HK3 RAC2 ST6GALNAC4 PLK3 JUNB ATP11A RHOG IFNGR1 CSTA GLIPR1 DAPK2 GMFG IDS RAB8A SNX1 RPS6KA1 REL TNFRSF10B RASSF2 GFPT2 CST7 SNRK CELF2 CD34 ACSL1 PLCG2 NKG7 MME TGFB1 SFTPC SERPINB1 CD6 FPR2 CD86 NFYC PIM1 SOD2 DOK2 ORM2 CCR1 FCGRT KYNU ANKRD12 RGS2 PLEKHO2 CLEC2B PDE4B SELPLG TNFAIP8 HTR6 IQSEC1 CXCR4 UBE2D1 SP100 MEGF9 IFFO1 S100A4 ICAM3 CTSC KLRK1 MMD P2RX1	down	***
MODULE_403	0.0000083	0.0000971	0.5933255	0.5879468	2.108236	42	CDC45 NEK2 CCNB1 CDK4 PLK1 CENPA MYBL2 MELK MKI67 TOP2A ATR MCM3 TOPBP1 CDK1 E2F1 UNG FEN1 RECQL4 TK1 DTYMK CDC20 FTCD RPA1 UBE2V2 MCM6 SNX11 MSH2 CHD3 TRUB1 CDC25B	up	***
GNF2_JAK1	0.0001633	0.0014444	0.5188481	-0.5789240	-2.101278	27	GPR65 FYN CTSW PTPRC PPP2R5C KLRB1 JAK1 PTGER2 SNRK BIN2 GSAP CLEC2B CYTH1 PRKCH ITGAL	down	**
GCM_PTPRD	0.0000418	0.0004152	0.5573322	-0.4845711	-2.091765	52	CCDC88A KIAA1109 PLEKHA1 ACER3 ZEB2 DNAJB14 TTL NLK SPIRE1 TTYH2 ABHD6 MOAP1 PEG3 DOCK9 BACE1 GZF1 MAP4K4 FRYL NAA30 CLASP2 ARPP19 SIK3 MEGF9 ULK2 KIF1B	down	***
MORF_ESPL1	0.0000075	0.0000901	0.6105269	0.5590618	2.081973	51	FOXM1 BUB1B PLK1 AURKB ESPL1 MCM2 TYMS ZWINT NUDT1 BUB1 CCT5 POLA2 KIF11 MCM3 DNAJC9 SSBP1 GOT2 FEN1 DNMT1 SNRPA LMNB2 SSRP1	up	***
GCM_CSNK1A1	0.0001266	0.0011557	0.5188481	-0.5334268	-2.063890	34	SEC22C ARL8B OTUD4 PPP1R15B FOXJ3 TOR1AIP1 FBXL5 RSRC2 DHX15 TMEM167B OCIAD1 GNA13 C1orf52 MED17 HIPK1 SENP6 EIF3J ANKRD17 PRPF8 YME1L1 PCNP RBM25	down	**
MODULE_44	0.0000000	0.0000000	0.8390889	-0.3680735	-2.059848	266	TNR SLPI ACP5 CD52 PECAM1 FABP4 CLEC3B LPXN CYP4B1 LIPA ENG CD44 CAV1 FXYD2 MAL FUCA1 CD22 EPB41L3 TGFBR2 RFTN1 HSPG2 CD8A APOD ASAH1 RNASE1 LCP1 LAIR1 GRN SRGN TCAP APOC1 CD37 KRT4 PTPN12 EVI2B CFD STAT5A SCP2 BIRC2 GPA33 CPVL DAB2 CLDN5 GMPR LAPTM5 PTPRC SELL PNRC1 IGFBP2 M6PR CD53 PER1 ALOX5AP N4BP2L1 IL7R HLA-DQA1 CRIM1 ARHGDIB EMP3 CD8B FAM107A METAP1 SLCO2B1 AQP3 CD48 RAB31 ETS1 RAC2 RHOG IFNGR1 JAK1 PIK3R1 IRF8 GMFG RASSF2 CELF2 CD34	down	***
GNF2_RAN	0.0000010	0.0000131	0.6435518	0.5107933	2.057069	79	KIF20A GMPS CCT6A NCAPD2 CCT2 NME1 RANBP1 MELK MRPL15 CCT5 PRKDC MRPL3 MCM3 EMG1 ETFA CKS1B SSBP1 CCT3 ATIC SNRPE PA2G4 POLR2H PSMA5 SNRPA SSRP1 CCT7 CDC20 MRPS33 SNRPD1 LSM4 PRMT5 BANF1 SNRPD2 PAICS SNRPC ADSL MSH6 XRCC5 NAE1 LRPPRC MTHFD2 CTPS1 BUB3 MRPL35 RFC3 RFC4	up	***
GNF2_PA2G4	0.0000037	0.0000475	0.6272567	0.5142454	2.039816	75	BUB1B NUP107 NDC80 CDK4 GMPS MCM4 CCT6A CCT2 LSM5 RANBP1 MELK MRPL15 CCT5 MCM7 MRPL3 MCM3 CAD ETFA CKS1B SSBP1 CCT3 GMNN SF3B3 SNRPE PA2G4 CHCHD3 SNRPA SSRP1 CENPM MCM5 SNRPD1 LSM4 BANF1	up	***
MODULE_342	0.0000000	0.0000003	0.7477397	0.4473890	2.039449	178	LTF TSPAN8 MUC13 FOXA3 EGLN3 CDH17 KRT5 LAD1 PRSS2 WFDC2 GINS1 PRR15L E2F8 DNMT3B LAMP5 AKR1C1 H19 C4orf19 AGR2 SPINT2 GRB7 XDH LILRB4 DZANK1 CYP3A5 GPX2 MAP7 LAMC2 FOXA1 F2RL1 MYO10 FGG CDCA5 RNF43 HOOK1 CD24 SLC9A3R1 B3GNT3 LRRC37A4P MST1R PRMT6 BACE2 LRRC61 PTGFRN WWC1 MIPOL1 CXCL14 KRT18 FAT1 PLA2G2A REEP6 LRRC4 CDH3 SLC25A18 NGFR MMP7 GALNT3 KRT19 FXYD3 CA11 LIPG UBXN6 KRT8 ANXA9 SSH3 RTKN RHOBTB1 ANK3 EPCAM PRSS8 CDH1 FMOD AIFM2 WLS PTPRF VWA1 FBLIM1 FZD3 RAB25 TMEM98 NUP210 KRT17 MUC1 AZGP1	up	***
MODULE_492	0.0007977	0.0061451	0.4772708	-0.6777587	-1.998140	13	FUCA1 ASAH1 ATP6V1B2 GLB1 HEXB	down	**
GNF2_CDH3	0.0003544	0.0030407	0.4984931	0.6353196	1.996481	23	COL17A1 GPR87 TP63 S100A2 FERMT1 LAMC2 GJB3 CDH3 KRT19 AHNAK2 PTHLH FGFBP1 KRT17	up	**
MODULE_84	0.0000000	0.0000000	0.9759947	-0.3394330	-1.990833	449	SLPI ACP5 CD52 MS4A7 FCN1 CXCL16 OLR1 TSPAN4 PECAM1 IL1B FABP4 MNDA CLEC3B CYP27A1 GPR65 PTPRE LIPA RAMP2 TRPV2 ENG LMO2 CAV1 AQP9 CHIT1 STX11 MAL MARCO BCL2A1 NCF2 IL1RN CD22 EPB41L3 TGFBR2 IGSF6 LILRB3 HSPG2 CD8A FGR DNASE1L3 PDE2A APOD ANXA1 PLA2G7 MAN2B1 BMP1 SLC7A7 IFI30 ANPEP RNASE1 SLC7A11 LCP1 STOM LAIR1 GRN CES1 SRGN ADAMTSL4 APOC1 CD37 KRT4 GMEB1 EVI2B CFD CASP1 TNFSF12 CPVL DAB2 SLC7A8 STK17B CLDN5 PLBD1 CCL3 LAPTM5 CDKN1A PTPRC SELL CCL4 CD302 PNRC1 IGFBP2 CCND2 M6PR CD53 PRF1 FCER1G PER1 ALOX5AP PLEK EVI2A N4BP2L1 IL7R MYH11 HLA-DQA1 CRIM1 VWF ARHGDIB HCK NINJ1 EMP3 KCNA5 CD8B S1PR4 IL6 CTSS IL2RB SLCO2B1 CD48 STAT4 RAB31 HK3 RAC2 ST6GALNAC4 TYROBP JUNB IFNGR1 CSTA IRF8 GMFG GFPT2 CST7 CELF2 ACSL1 RUNX3 NKG7 CD74 MME TIMP2 SFTPC CD6 FPR2 LRRC32 CD86 LGALS3 ORM2 CCR1 FCGRT KYNU PLEKHO2 CLEC2B PDE4B TAGLN ICAM1 SELPLG GPX3 TNFAIP8 SEMA4A SPIB MS4A4A CXCR4	down	***
GNF2_PAK2	0.0015643	0.0103243	0.4550599	-0.5478802	-1.958982	25	MYD88 BNIP2 SELL ACTR3 CD53 ARHGDIB ACTR2 GMFG ADAM10 ACAP2 ARPC5 PAK2 CNOT8	down	*
GNF2_CD97	0.0008312	0.0062562	0.4772708	-0.5165274	-1.945461	31	GPR65 GIMAP6 LITAF OSTF1 PTPRC ID2 JAK1 PTGER4 PTGER2 BIN2 DOK2 CLEC2B SELPLG IQGAP1 CX3CR1 AOAH ITGAL MYO1F APOBR IL10RA CYTIP STK10 ADCY7	down	**
MODULE_191	0.0010146	0.0073155	0.4550599	0.6904650	1.943506	15	LTF TF CCL19 CP	up	**
GNF2_ICAM3	0.0009083	0.0067180	0.4772708	-0.5199191	-1.939630	29	HSD17B11 TXNIP DPEP2 EVI2B PTPRC SELL EMP3 GMFG ARRB2 ACAP2 ICAM3 DAZAP2 SH3BGRL3 IRF1 MYO1F APOBR TMEM127 HCLS1 ARHGAP25	down	**
GNF2_MSH2	0.0009487	0.0068979	0.4772708	0.5935075	1.923751	26	FANCI NDC80 GINS1 TOP2A MCM7 MCM3 LIG1 RAD51AP1 FEN1 SUPT16H MCM6 SNRPD1 TCERG1 MSH2 MSH6 LRPPRC SMC4 RFC4 ITGB3BP PCNA	up	**
MODULE_262	0.0014913	0.0099187	0.4550599	0.6939784	1.922220	14	LTF TF CCL19 CP	up	**
MODULE_252	0.0000001	0.0000010	0.7195128	0.4156144	1.920151	219	CCNO TRIP13 FOXM1 CDC45 NUP107 NEK2 COIL CCNB1 CENPF NDC80 PRIM2 CDK4 PLK1 CENPA PTTG1 SOX9 E2F3 CCNB2 MYBL2 ORC1 NCAPD2 ZWINT NME1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A POLD2 KIF2C MSX1 PRKDC WDHD1 RAD54L ZNF146 MCM3 CHAF1B LMNB1 CDC25C SOX4 LIG1 TOPBP1 ACTL6A MAD2L1 NFYA CDKN2C CBX5 CDK1 POLE2 BIRC5 E2F1 UNG PSMB5 FEN1 EZH2 TAF6 SNRPE CBX1 PSMC4 VPS72 RECQL4 DNMT1 ILF2 RAD51D SSRP1 NFATC4 HDAC1 SAP30 POLD1 PSMD2 CDC7 POP7 RPA1 MCM6 STAMBP SRPK2 SNRPD1 DDX23 NEK4 SRSF1 KATNB1 RCC1 MSH2 CCNA2 PRIM1 STK38 RFC5 RAD51 ZNF217 SMC2 CENPE APEX1 SNRPC PNN TAF4 PPP2R5D KRT17	up	***
GNF2_MLH1	0.0004385	0.0036525	0.4984931	0.5523487	1.917306	36	FANCI NUP107 NDC80 CCT2 KNTC1 CCT5 CBX3 MCM3 SNRPE PA2G4 ILF2 SSRP1 SUPT16H SNRPD1 SRSF1 TCERG1 MSH2	up	**
MODULE_198	0.0000000	0.0000002	0.7614608	0.4081319	1.917026	272	CCNO TRIP13 FOXM1 CDC45 TFAP2A NUP107 NEK2 COIL CCNB1 CENPF NDC80 PRIM2 SPDEF POLE PLK1 CENPA PTTG1 ESPL1 SOX9 E2F3 CCNB2 RBBP8 MYBL2 ORC1 NCAPD2 ZWINT NME1 SMARCC1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A POLD2 KIF2C MSX1 PRKDC SETDB1 RAD54L ZNF146 MCM3 CHAF1B LMNB1 CDC25C SOX4 LIG1 TOPBP1 CHEK1 ACTL6A MAD2L1 NFYA BLM TULP3 CDKN2C CBX5 CDK1 POLE2 E2F1 UNG PSMB5 FEN1 EZH2 TAF6 SNRPE CBX1 PSMC4 VPS72 RECQL4 KPNB1 DNMT1 FANCG ILF2 CCNE1 KIF22 RAD51D SSRP1 ADAR NFATC4 HDAC1 SAP30 KRT19 POLD1 PSMD2 CDC7 AP3M2 POP7 RPA1 MCM6 STAMBP SRPK2 SNRPD1 DDX23 NEK4 SRSF1 KATNB1 RCC1 BCL9 MSH2 CCNA2 PRIM1 ZNF195 STK38 GTF3C2 RFC5 RAD51 ZNF217 SMC2 CENPE APEX1 SNRPC PNN TAF4 PPP2R5D KRT17	up	***
MODULE_337	0.0001667	0.0014598	0.5188481	0.5135001	1.912299	51	MDM1 CDC45 CENPF SEMA4B ORC1 SRPK1 NCAPD2 NME1 KCNN4 NUP155 RRM2 SPEF2 ANKEF1 GPSM2 NFYA ALG3 UCK2 GMNN E2F1 NUP205 RAB6B SNRPA PLEKHA8 ACLY ALMS1 HLCS ARHGAP11A MRTO4 PLK4 UTP18 ADSL	up	**
GNF2_TYK2	0.0013658	0.0093001	0.4550599	-0.5072129	-1.892227	29	LRRFIP1 MANBA EIF1 LCP1 BNIP2 ARHGDIB ACTR2 NCKAP1L DDX5 MOB1A ADPGK PAK2	down	**
MODULE_75	0.0000000	0.0000001	0.7614608	-0.3311746	-1.891427	308	EREG IL1A FCN1 CD101 TEK CD55 IL1B MNDA EMP2 GPR65 INSIG1 FYN LY86 FCER1A AQP9 CHIT1 C5AR1 NCF2 CD1C GAS6 CD22 IGSF6 LILRB3 CD8A FGR ERG DNAJC3 CD5 HBEGF ADA BTG2 MAP3K8 KLF6 MS4A1 GATA3 IL18R1 GRN CES1 ZEB1 MTHFR PDGFA STAT5A BST1 TNFSF12 PTAFR DAB2 CCL3 CDKN1A CXCL2 SELL SELP CCL4 SFTPD CD53 PRF1 FCER1G CD300C EVI2A IL7R C4BPB IL24 ARHGDIB SNN BTG1 EMP3 CD8B AREG IL6 CTSS IL2RB OASL CD48 C1QA ETS1 TYROBP IFNGR1 PTGER4 CD83 IRF8 GMFG GPR183 OSM CXCL5 CST7 RUNX3 CR1 CD6 CD86 PDCD1 CD81 ORM2 CCR1 FCGRT CLEC2B CCL20 GEM GPX3 IL18 LAT CXCR4 CCR9 EPHA2 DAPK1 CD19 BCAT1 NFKBIA ADORA2A CTSC EDN1 CD3G KLRK1 AIM2 CREG1 IL16	down	***
MODULE_244	0.0000017	0.0000219	0.6435518	0.4202107	1.889147	162	TRIP13 DDX11 AK4 CHEK2 NEK2 PRIM2 TTK CDK4 KIF14 GMPS POLE PLK1 ORC1 CCT6A EPHB1 NME1 MELK KIF23 MKI67 HLTF KIF3B BUB1 TOP2A POLD2 KIF2C COASY RAD54L KIF11 MCM3 PEX6 LIG1 CHEK1 BLM CDK1 POLE2 MERTK TRAP1 PSMC4 RECQL4 STK11 ILF2 GSS KIF22 MAPK13 EPHB2 TK1 DTYMK POLD1 MAT1A CDC7 POLR2J MCM6 MED24 SRPK2 DDX23 NEK4 PFKFB4 PMS1 MSH2 PRIM1 STK38 RFC5 NME4 RAD51 CDK5 SMC2 CENPE MTHFD1 SEPHS1 TIMM44 MAP2K2 ERCC3 ROR2	up	***
MODULE_124	0.0000635	0.0006052	0.5384341	0.4536282	1.870338	91	DDX11 CCNB1 IGF2BP3 NDC80 TBRG4 CDK4 PLK1 PTTG1 E2F3 CCNB2 CDC25A NCAPD2 DCTN2 SMARCC1 KIF23 KNTC1 BUB1 KIF2C MAD1L1 EMG1 ACTL6A MAD2L1 PPP5C CDK1 BIRC5 E2F1 TAF6 CCNE1 CDK3 KIF22 TCEA1 CDC7 RRP9 POLR2J NEK4 POLR2I RCC1 CCNG1 CCNA2 SMC2 CHERP CDC25B UBE2C	up	***
MODULE_118	0.0000000	0.0000000	0.7881868	0.3900439	1.870006	337	RIBC2 TRIP13 PLAT DDX11 ENTPD2 FOXM1 BIK CDC45 TROAP BUB1B PROM1 PRSS2 CCNB1 CENPF IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 NDC80 SORD ECE2 GTSE1 KIF14 GMPS SPP1 MMP1 PLK1 CENPA PTTG1 TPX2 CCNB2 MCM4 MCM2 MYBL2 CCNF SRPK1 NCAPD2 ZWINT TNC CASP2 HMMR NUDT1 KCNN4 CHAF1A MKI67 PRB4 KNTC1 PAFAH1B3 TOP2A MYO10 CARD10 POLD2 MPO RRM2 SLC22A18AS RAD54L KIF11 MCM3 LMNB1 SOX4 SALL2 MDK RBP1 CD24 SLC9A3R1 TOPBP1 MAD2L1 SCAMP5 MSI1 ABCB9 PKMYT1 FADS2 CLDN9 MGLL RECQL5 CDKN2C TMEM106C PLOD2 KRT18 CDK1 EXOSC2 NPM3 E2F1 UNG PEG10 FEN1 EZH2 NUP205 TTI1 IGSF3 RECQL4 RNASEH2A TBX1 LGR5 DLGAP5 CHST3 ALDH7A1 LMNB2 COL5A2 DPH2 DTYMK DBN1 FZR1 IGHM KRT19 OLFML2B MAT1A DNASE1 CHPF	up	***
MORF_PHB	0.0000421	0.0004152	0.5573322	0.4402261	1.861572	106	DDX11 TOMM34 RBBP8 CIB1 WDR62 TP53BP1 BPHL TPR ERAL1 CDC25C PKMYT1 CAD FDXR PHB DYRK2 MEA1 PABPN1 RTCB DNAJC7 EIF6 FANCG ILF2 MLEC PSMD2 COPS6 SH2B1 TSTA3 CPSF4 SRRT MRPL28 TFAP4 AATF NUP62 MCRS1 NFRKB BMS1 RPRD2 CHD3 ADAM15 PWP1 PLIN3 ILVBL PRKAG1 XPO6 PCGF2 DRG1 NELFB TUBGCP2 MPST HMG20B SPRN CS PSMD3	up	***
MORF_JUND	0.0004700	0.0038771	0.4984931	-0.4263049	-1.858990	54	IER2 RHOA FBXO7 MCL1 RPL17 NXF1 RPL9 DDX5 UBB RPL21 JUND TPT1 HNRNPK DAZAP2 EIF4A2 EIF4G2	down	**
MORF_FEN1	0.0005993	0.0048513	0.4772708	0.4975368	1.855715	52	FOXM1 CCNB1 CDK4 ESPL1 EIF3B ZWINT CCT2 CCT5 MCM7 MCM3 DNAJC9 SSBP1 CCT3 UNG FEN1 NUP205 VBP1 LMNB2 MCM6 SRSF1 POLR2I LSM4 ALG8 VDAC1 EIF4G1 MTHFD1 CHERP	up	**
GNF2_PTPN6	0.0021930	0.0140416	0.4317077	-0.4685272	-1.854648	38	LRRFIP1 TXNIP DPEP2 EVI2B FAM49B LAPTM5 PTPRC SELL CD53 ARHGDIB EMP3 CD48 RAC2	down	*
MODULE_189	0.0033807	0.0201434	0.4317077	0.7332818	1.846717	10	CENPA CHAF1A SETDB1 CHAF1B EZH2 CBX1	up	*
GNF2_MATK	0.0062463	0.0337371	0.4070179	-0.5228682	-1.843398	24	CTSW PRF1 KLRD1 MATK KLRB1 IL2RB NKG7 IL18RAP KLRK1 PRKCH S1PR5	down	*
GNF2_MCM5	0.0007008	0.0055674	0.4772708	0.4809640	1.827002	56	CPSF6 NDC80 GINS1 CDCA8 MCM4 MCM2 TYMS DTL ZWINT TOP2A POLA2 MCM7 MCM3 LMNB1 TOPBP1 FEN1 SF3B3 PA2G4 SSRP1 GINS2 CENPM MCM5 SRSF1 NUP62	up	**
MODULE_127	0.0019657	0.0126810	0.4317077	0.6895428	1.824200	12	CENPA CHAF1A SETDB1 CHAF1B EZH2 CBX1	up	*
MODULE_46	0.0000000	0.0000009	0.7195128	-0.3195695	-1.817446	303	EREG IL1A FCN1 CD101 CD55 IL1B MNDA EMP2 GPR65 INSIG1 FYN LY86 FCER1A AQP9 CHIT1 ADRA1D C5AR1 NCF2 CD1C GAS6 CD22 IGSF6 LILRB3 CD8A FGR ERG DNAJC3 CD5 HBEGF ADA ENTPD1 KLF6 MS4A1 GATA3 IL18R1 GRN ZEB1 MTHFR PDGFA STAT5A BST1 TNFSF12 PTAFR DAB2 CCL3 CXCL2 SELL SELP CCL4 SFTPD CD53 PRF1 FCER1G CD300C EVI2A IL7R C4BPB IL24 ARHGDIB BTG1 EMP3 CD8B AREG IL6 CTSS IL2RB OASL CD48 C1QA ETS1 TYROBP IFNGR1 PTGER4 CD83 IRF8 GPR183 OSM CXCL5 CST7 RUNX3 KLRC2 CR1 CD6 CD86 PDCD1 CD81 ORM2 CCR1 FCGRT CLEC2B CCL20 GEM GPX3 IL18 LAT CXCR4 CCR9 CD19 BCAT1 NFKBIA ADORA2A CTSC EDN1 CD3G KLRK1 AIM2 CREG1 IL16	down	***
MODULE_178	0.0047021	0.0265422	0.4070179	-0.6157105	-1.815212	13	EPAS1 ANPEP TNFSF12 MMP19 FGF2 IL18 NRG1	down	*
MODULE_357	0.0008082	0.0061451	0.4772708	0.4792439	1.812261	55	COL17A1 SAA1 TFPI2 TP63 KRT5 S100A2 TENM2 COL7A1 AKR1C1 KRT15 GPX2 LAMC2 F2RL1 TRIM29 ITGB4 CDH3 HAS3 S100A9 KRT19 FXYD3 LIPG CXCL1 PTHLH FBN2 FGFBP1 KRT17 BARX2 KLK10 PTPRK ROPN1L	up	**
MODULE_297	0.0003850	0.0032383	0.4984931	0.4805669	1.810743	54	COL17A1 SAA1 TFPI2 TP63 KRT5 S100A2 TENM2 COL7A1 AKR1C1 KRT15 GPX2 LAMC2 F2RL1 TRIM29 ITGB4 CDH3 HAS3 S100A9 FXYD3 LIPG CXCL1 PTHLH FBN2 FGFBP1 KRT17 BARX2 KLK10 PTPRK ROPN1L	up	**
MORF_RFC4	0.0000272	0.0002842	0.5756103	0.4171923	1.805846	126	TRIP13 BUB1B NDC80 KIF14 ESPL1 MCM2 TYMS SRPK1 SHMT2 XPOT ZWINT RUVBL2 HMMR CHAF1A SDHA BUB1 TOP2A CCT5 PRKDC TRRAP RAD54L MCM3 DNAJC9 ACTL6A CAD ALG3 SSBP1 GOT2 UNG PMEL SPAG5 KXD1 DNMT1 ILF2 SNRPA SSRP1 MLEC TCEA1 DNAJC11 RPA1 MCM6 SRSF1 MSH2 CCNA2 DOCK3 VDAC1 SNRNP200 VDAC3 ZNF131 MRPS27 GPN1 LYPLA1 AKR7A2 DGUOK TNPO3 SAFB CS NAE1 HNRNPAB LRPPRC	up	***
GCM_DEAF1	0.0095311	0.0465819	0.3807304	-0.5001972	-1.803506	26	RAPGEF2 KIAA1109 DNAJB14 RAB14 MOAP1 UBQLN1 NAPG DDHD2 G3BP2 TMEM184B FOXJ2 TMEM30A GPR153	down	*
MODULE_98	0.0000000	0.0000009	0.7195128	0.3737885	1.801890	350	CCNO TRIP13 FOXM1 CDC45 TFAP2A NUP107 NEK2 COIL CCNB1 CENPF CPSF6 NPAS1 NDC80 NOVA1 PRIM2 SPDEF POLE PLK1 YEATS4 CENPA PTTG1 ESPL1 SOX9 E2F3 CCNB2 RBBP8 ZNF117 MYBL2 ORC1 NCAPD2 ZWINT NME1 MAP7 SMARCC1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A POLD2 TPR KIF2C MSX1 PRKDC SETDB1 RAD54L ZNF146 MCM3 CHAF1B LMNB1 CDC25C SOX4 EMG1 LIG1 TOPBP1 CHEK1 ACTL6A MAD2L1 NFYA FBL BLM TULP3 CDKN2C CBX5 CDK1 POLE2 GTF2E1 E2F1 UNG PRRX2 PSMB5 FEN1 EZH2 TAF6 SNRPE CBX1 PSMC4 VPS72 RECQL4 KPNB1 DNMT1 FANCG ILF2 CCNE1 PSMA5 ZNF133 SNRPA MBD4 KIF22 RAD51D ARF5 SSRP1 ADAR NFATC4 HDAC1 SAP30 KRT19 NRF1 POLD1 PSMD2 CDC7 PPP1R8 AP3M2 POP7 RPA1 POLR2J MCM6 STAMBP SRPK2 SNRPD1 DDX23 NEK4 SRSF1 KATNB1 RCC1 PMS1 BCL9 MSH2 CCNA2 PRIM1 ZNF195 STK38 GTF3C2 RFC5	up	***
MODULE_303	0.0041181	0.0237483	0.4070179	0.5455388	1.797328	27	BUB1B NEK2 TTK CDK4 PLK1 BUB1 CHEK1 CDK1 ULK1 CDK3 MAPK10 CDC7 CSNK1G2 ECHS1 CDK5	up	*
GCM_DPF2	0.0035611	0.0209275	0.4317077	0.5711285	1.794761	23	HMGA2 TP53BP1 FUT2 VPS72 DGCR6 COX10 AAMP TTC1 BCAT2 PRKAG1 BNIP1 SDHC MPP2 RFX5 SMARCD1 DRG2 ADCYAP1	up	*
MODULE_53	0.0000002	0.0000030	0.6901325	0.3745087	1.794446	323	RIBC2 TRIP13 DDX11 ENTPD2 FOXM1 BIK CDC45 TROAP BUB1B CCNB1 CENPF IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 NDC80 ECE2 GINS1 GTSE1 KIF14 GMPS PLK1 CENPA PROC PTTG1 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 CCNF SRPK1 SHMT2 NCAPD2 ZWINT CASP2 HMMR NUDT1 KCNN4 CHAF1A MKI67 PRB4 KNTC1 PAFAH1B3 EEF1E1 TOP2A CARD10 POLD2 KIF2C MPO RRM2 PRKDC SLC22A18AS RAD54L KIF11 MCM3 LMNB1 SOX4 SALL2 MDK CD24 TOPBP1 MAD2L1 SCAMP5 MSI1 ABCB9 PKMYT1 BLM FADS2 CLDN9 RECQL5 CDKN2C TMEM106C CDK1 EXOSC2 NPM3 E2F1 UNG PEG10 FEN1 EZH2 NUP205 ARTN TTI1 CBX1 RECQL4 RNASEH2A TBX1 DNMT1 LGR5 DLGAP5 LMNB2 DPH2 DTYMK DBN1 FZR1 PCDH9 IGHM ASNS OLFML2B MAT1A CDC7 DNASE1 CHPF KLHDC3 CKAP5 CDC20 RRP9 RPA1 WNT10B MCM6 KIF21B	up	***
MODULE_1	0.0000000	0.0000006	0.7337620	-0.3120833	-1.787666	320	SLPI PECAM1 CD55 CLEC3B EMP2 ENG CD44 CAV1 CITED2 TGFBR3 FUCA1 TGFBR2 RFTN1 HSPG2 HEG1 ANXA1 MAN2B1 LMNA CSRP1 KLF10 RNASE1 CAV2 NR4A1 NFE2L2 SFRP1 SRGN TFRC CNN1 TIPARP RHOB PTPN12 CFD SCP2 SRSF5 BIRC2 KLF4 AOC3 PEG3 DAB2 GMPR CCL3 CDKN1A KCNMB1 ATF3 CD302 PNRC1 IGFBP2 CCND2 PER1 ADIPOR2 WFS1 ACTG2 VAMP5 MYH11 PTGIS HES1 MAFF CRIM1 MAPRE2 VWF EMP3 IL6 SGK1 LAMB2 JUN MITF RAB31 LTBP2 JUNB RABGAP1 IFNGR1 PPP1R15A MFAP4 FSTL3 TNFRSF10B RASSF2 GFPT2 WDR7 CD34 CD151 FOS FOSB TIMP2 AOX1 PIM1 COL15A1 ORM2 FCGRT RGS2 LTBP1 CLEC2B MBNL1 SOD3 GEM GPX3 PDLIM5 CPQ LMOD1 CDKN1C BCAM MTUS1 FGFR1 LDLR IQGAP1 EGR1 SERPINE1 C1QB DUSP6 SVIL NR4A2 LHFPL2 ZYX EFS QSOX1 GNG11 AKAP12 DDX21 TES NFIL3 WWTR1 SLC23A2 ITGA6 PDPN LRP1 PKD1 DUSP2 FBLN1 EMP1 CHGA MYL9 ADAM19 MYLK	down	***
GCM_MSN	0.0093417	0.0463305	0.3807304	-0.5063700	-1.785233	24	SPN RHOA SRSF2 HMGN1 TAF9 ARHGDIB DDX5 YWHAZ HNRNPD SF1	down	*
GNF2_PTPRC	0.0011442	0.0079827	0.4550599	-0.4073974	-1.776540	54	GPR65 GIMAP6 TXNIP FLI1 OSTF1 PTPRC CD53 HECA CD48 RAC2 JAK1 DDX5 SNRK KLF2 BIN2 GSAP PHF11 CLEC2B MBNL1 ICAM3 CYTH1	down	**
MODULE_2	0.0000001	0.0000016	0.7049757	-0.3087819	-1.774078	314	RBP4 SLPI STAC PECAM1 FABP4 CLEC3B EMP2 CYP4B1 LIPA RAMP2 CDH5 INSIG1 ENG LPL CD44 CAV1 MAL TGFBR3 EPB41L3 TGFBR2 RFTN1 HSPG2 APOD ANXA1 ASAH1 CSRP1 CYB5A GLS CAV2 NR4A1 SFRP1 ZEB1 SRGN TFRC CD37 CNN1 EPB41L2 RHOB CFD TBC1D9 MOAP1 SCP2 BIRC2 AOC3 CLDN5 PDE8A CCL3 LAPTM5 CDKN1A CADM1 PTPRC ATF3 CCND2 PER1 ADIPOR2 ACTG2 MYH11 HLA-DQA1 HES1 MAFF CRIM1 MAPRE2 VWF EMP3 LAMB2 CYB5R1 JUN LTBP2 JUNB ARHGEF10 RABGAP1 IFNGR1 PPP1R15A MFAP4 FSTL3 TNFRSF10B CD34 ACSL1 CD151 FOS MBP MSMO1 MME COL15A1 FCGRT RGS2 LTBP1 ETS2 MBNL1 SOD3 SYT11 GEM GPX3 TFPI RTN1 CXCR4 CDKN1C MEGF9 S100A4 TIMP3 MTUS1 MMD FGFR1 LDLR GRB10	down	***
MODULE_154	0.0011444	0.0079827	0.4550599	0.4763098	1.773800	51	COL17A1 SAA1 TFPI2 TP63 KRT5 S100A2 TENM2 COL7A1 AKR1C1 GPX2 LAMC2 F2RL1 TRIM29 ITGB4 CDH3 HAS3 S100A9 FXYD3 LIPG CXCL1 PTHLH FBN2 FGFBP1 KRT17 BARX2 KLK10 PTPRK ROPN1L	up	**
MODULE_540	0.0094882	0.0465819	0.3807304	0.7030345	1.770541	10	LTF TF CP	up	*
GNF2_DDX5	0.0027978	0.0172700	0.4317077	-0.4017768	-1.768831	57	YPEL5 CCNL1 HNRNPDL SRSF5 BIRC2 BNIP2 PTPRC RSRC2 ACTR2 UFM1 RBM39 NXF1 HECA SF3B1 DDX5 RBM22 SRSF6 ADPGK PHF11 MBNL1 TRAPPC8 YTHDC1 CRBN SCAF11 STX16 SETD2 SCAF8 VPS13C	down	*
GNF2_MSH6	0.0029885	0.0183154	0.4317077	0.5307158	1.767761	29	GMPS CCT2 RANBP1 PRKDC MCM3 LIG1 MAD2L1 CCT3 SNRPE MSH2 PAICS MRPS27 ADSL MSH6 LRPPRC MTHFD2 RFC3 RFC4 ITGB3BP	up	*
MODULE_146	0.0008036	0.0061451	0.4772708	-0.3800438	-1.759656	73	HCRTR1 GPR17 EDNRB GPR65 CALCRL ADCYAP1R1 C5AR1 CHRNE ADRB1 ADRB2 NPR3 PTGER3 PTH1R S1PR4 HCAR3 PRPH2 HRH1 GPR183 PTGER2 GPR3 FPR2 CCR1 HTR6 CXCR4 ADORA2A GPR171 LPAR6 CX3CR1 FPR1 BDKRB2 FPR3	down	**
MODULE_280	0.0041241	0.0237483	0.4070179	0.5001458	1.749726	38	LTF MMP13 TF PTPRZ1 HS3ST1 CP SORD MMP1 ZNF117 PAH ZNF146 ADAM12 MMP7 ECEL1 POLR2I SUOX	up	*
GCM_HBP1	0.0014776	0.0099042	0.4550599	-0.3892198	-1.745389	60	USP47 RANBP9 SLAIN2 FOXJ3 LAMTOR3 ZFAND5 CUL5 PPIL4 PRKRA COPS2 NAA30 RRN3 RNASEK YTHDF3 MAP3K2 HBP1 HNRNPH3 COMMD9 USPL1 TAB2 FNBP4 C1orf52 MED17 TBC1D23 SCAF8 KANSL3 MTDH PHACTR4 PRPF8 ZC3H14 PCNP IRF2BP2 RBM25 ZNF644 PPM1B	down	**
MODULE_552	0.0030150	0.0183465	0.4317077	0.8305510	1.744114	6	CENPA MYBL2 EZH2 CBX1	up	*
GCM_PTK2	0.0001607	0.0014363	0.5188481	-0.3408707	-1.737226	131	MGAT3 CLDND1 CCDC88A KIAA1109 PLEKHA1 AGPAT4 EPB41L3 TEX2 ZEB2 DNAJB14 TTL NLK SPIRE1 TTYH2 ABHD6 MOAP1 CCDC82 PEG3 DOCK9 BACE1 FMNL2 GZF1 MAP4K4 FRYL NAA30 OCIAD1 NAPG DDHD2 MTMR2 FAXDC2 PPIG WBP2 NPTN CLASP2 PHLPP2 ARPP19 GLTP RTN4 TMOD2 SIK3 MEGF9 TMEM184B ULK2 CCDC92 FNIP2 KIF1B RNF13 RABGEF1 TMEM30A FAM8A1 DYNC1I2 DIRAS1 KIDINS220	down	**
MODULE_64	0.0000000	0.0000002	0.7614608	-0.2992578	-1.731716	405	SLC6A4 EREG RAMP3 IL1A TEK OLR1 TSPAN4 ASGR1 EDNRB CD55 SFRP4 SPN IL1B SLC16A4 GPR65 PTPRE THBD BMP2 FOLR1 SLC10A1 FCER1A CAV1 CALCRL AQP9 C5AR1 FXYD2 MAL CD1C CD9 CD22 IGSF6 LILRB3 CD8A FGR ANXA1 PTPRM CD5 HBEGF KCNK3 CHRNE MAP3K8 ANPEP PRSS12 MS4A1 STOM ADRB2 IL18R1 GRN CD37 GPM6A PTGIR EPOR PTPRO GPA33 TNFSF12 PTAFR PLAUR GRK5 NPR3 CCL3 LAPTM5 CDKN1A ITGAX PTPRC CXCL2 SELL AXL CCL4 JAM2 CD53 FCER1G CD300C EVI2A INHBA IL7R IL24 PTH1R NCKAP1L PDK4 CD8B S1PR4 HCAR3 FLT1 AREG IL6 IL2RB PRPH2 AQP3 STAT4 HK3 TYROBP IFNGR1 CD83 GYPC GPR183 OSM MAPK4 UNC13B RGS13 GPRC5A GRIK1 MCAM GPR3 NKG7 CD6 FPR2 DUSP5 LRRC32 CD86 CNTNAP1 GLRA1 LGALS3 CCR1 FCGRT RGS2 CLEC2B MLANA RXRA CCL20 ICAM1 LAT SCN7A HTR6 CXCR4 EPHA4 CCR9 EPHA2 ICAM3 DAPK1 CD19 KIT CD3G KLRK1 P2RX1 FGFR1 RORA LDLR NRG1 LPAR6 MS4A2 CSF2RB GHR AQP5 CNR2 DUSP6 KCNJ6 NR4A2 CX3CR1 PRKCH ITGAL FPR1 HAS2 BDKRB2 CD69 GNG11	down	***
MODULE_177	0.0008093	0.0061451	0.4772708	-0.3599082	-1.716156	87	CD52 LMO2 NR3C1 EDEM1 EIF5 LCP1 UBE2D3 TFRC RHOB FABP5 NFKB1 PTPRC CD53 HLA-DQA1 ARHGDIB BTG1 SGK1 CD48 CUL4A JAK1 CD83 GYPC CLN3 PLCG2	down	**
CAR_IGFBP1	0.0072770	0.0373872	0.4070179	0.5071758	1.715018	31	CPS1 ADH1C SLC27A2 PAH DPYS PON3 C6 TFR2 CYP2C8 DHODH ASGR2 HPD CFH	up	*
MODULE_306	0.0085801	0.0430508	0.3807304	0.5551655	1.712859	21	GAPDH ALDOC SDHA PKM PFKP IDH2 ALDOA PFKM PGAM1 ENO1	up	*
MODULE_18	0.0000013	0.0000175	0.6435518	0.3519679	1.709553	381	RIBC2 TRIP13 PLAT FOXM1 PAX9 TFAP2A BUB1B CCNB1 IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 GTSE1 GMPS SPP1 BAMBI MMP1 TOMM34 PLK1 AURKB CENPA PTTG1 TBX19 ESPL1 TPX2 RBBP8 MCM2 TYMS ORC1 CCNF CCT6A SHMT2 ZWINT INTS1 TNC CEP250 CASP2 NUDT1 CHAF1A PRB4 EEF1E1 TOP2A CBX3 MYO10 CARD10 POLA2 MCM7 MSX1 TTLL12 PRKDC SLC22A18AS MRPL3 KIF11 LMNB1 AIMP2 CDC42EP1 MAD2L1 SCAMP5 AHCY PSMD4 PKMYT1 CAD FDXR PPP5C CLDN9 TMED3 CDKN2C TMEM106C PLOD2 KRT18 CDK1 SSBP1 FAT1 UCK2 ARPC1A TNFRSF25 E2F1 UNG TRIM2 PEG10 FEN1 NUP205 FADD IGSF3 CBX1 PSMC4 ITGA2B ITPR3 TBX1 DNMT1 LGR5 VBP1 DLGAP5 TRIM16 SLC26A2 CHST3 LMNB2 TK1 DTYMK ASNS SLC4A2 FHL2 TWF1 TYRO3 MAT1A CKAP5 CDC20 IARS2 ERBB3 RPA1 CXCL1 MCM6 RCC1 WDR45B PDIA4 SLC1A5 LSM4 MCRS1 RPS26 CCNA2 CAP2 FKBP9 ACKR2 DLEC1 LPGAT1 TRIP6 HOXB2 CIAPIN1 TRIB2 MTHFD1 DHRS3 PAICS APEX1 SNRPC UBE2C PWP1 NUP93 WIZ CALU IFI16 NQO1 CYB5B TPM1 APOBEC3B MLLT11 RCN2	up	***
MODULE_485	0.0049187	0.0275834	0.4070179	0.4633008	1.707049	48	GRIK2 BDH1 POLE CDC6 MYBL2 GSDMB BUB1 MSX2 AURKA RRM2 HOOK1 CD24 FADS2 SSUH2 UNG DLGAP5 ARHGEF16 CELF4 NT5DC2 CCNA2 RBM42 CAP2 MCF2L2 NQO1 SLC40A1 PDK2	up	*
MORF_DDB1	0.0000310	0.0003201	0.5573322	0.3676353	1.701909	210	TRIP13 DDX11 EIF2B5 TOMM34 MCM2 CIB1 WDR62 RUVBL2 DNPH1 SDHA HLTF TP53BP1 BPHL TPR PRKDC TRRAP PEX6 CDC25C ACTL6A PKMYT1 CAD FDXR PHB CNOT3 ERCC2 ALG3 MEA1 KXD1 OARD1 TTI1 RTCB DNAJC7 EIF6 GOLGA3 FANCG ILF2 SSRP1 MLEC TCEA1 DAP3 SLC4A2 KDM3B PSMD2 COPS6 SH2B1 TSTA3 CPSF4 BRD8 AHCYL1 SRRT MRPL28 TFAP4 AATF PDIA4 SMARCC2 NUP62 DOCK3 NFRKB CSNK1G2 PDAP1 PRPF31 BMS1 SNRNP200 RPRD2 CHD3 PARG ADAM15 RANBP3 PWP1 PLIN3 ILVBL SART3 PRKAG1 PARP2 XPO6 PCGF2 DRG1 NELFB HUWE1 TUBGCP2 NSL1 MPST SPRN CS HNRNPAB LRPPRC UBE3C PSMD3 PDXDC1 DRAP1 BECN1 ACTN4 CLTC RABGGTA RAC1 DDB1 ATXN2L YIF1A PRKCSH DNAJC13 POLR2C SUMO4 CLSTN1 DDX46 RERE NCBP2	up	***
CAR_HPX	0.0073905	0.0377441	0.4070179	0.4731345	1.694740	41	CPS1 HP FGA SLC27A2 PAH DPYS PON3 AGT FGG C6 TFR2 ANG ALDOB CYP2C8 DHODH ASGR2	up	*
MORF_WNT1	0.0027308	0.0171027	0.4317077	0.4368731	1.694352	64	KIF1A MYBPH BHMT RPGRIP1L DOC2A CYP4F11 PDE9A FSTL4 TNNT2 NLE1 ODF2 TEKT2 WNT1 PHKG2 SPAG8 PTGDR2 ATP2A1 VPS41 ZNF239 NTN3 COX10 SEC14L2 RPGRIP1	up	*
GNF2_SPINK1	0.0085651	0.0430508	0.3807304	0.7670638	1.692465	7	CUZD1 PRSS2 SPINK1 CEL SERPINI2 PDIA2	up	*
MODULE_19	0.0000064	0.0000782	0.6105269	-0.3018609	-1.689118	262	EPAS1 SC5D CD55 FABP4 CLEC3B PHYHIP ENG LPL CITED2 ALAS1 TGFBR3 PDE4C FUCA1 EPB41L3 TGFBR2 HSPG2 ABCB1 TMX4 PDE2A APOD PTS CYB5A ACOT2 RNASE1 NR4A1 NFE2L2 SPTBN1 APOC1 KRT4 RHOB PTPN12 MAP2K3 CFD SCP2 BIRC2 EPOR AOC3 PEG3 DAB2 GMPR CADM1 CCND2 PER1 ADIPOR2 MYH11 MAPRE2 PTH1R EMP3 SGK1 LAMB2 RAB31 ST6GALNAC4 PLK3 JUNB PPP1R15A COBLL1 FSTL3 TNFRSF10B CLN3 WDR7 CD34 PLCG2 FOS PTP4A1 MSMO1 FOSB LRRC32 AOX1 COL15A1 FCGRT RGS2 MBNL1 PCCA SOD3 GPX3 CXCR4 CDKN1C ALDH6A1 GPD1L TIMP3 MTUS1 LDLR GRB10 IQGAP1	down	***
MORF_DNMT1	0.0011078	0.0078550	0.4550599	0.4021804	1.687592	101	BUB1B ESPL1 MCM2 TYMS SRPK1 ZWINT RUVBL2 NUDT1 CHAF1A CCT5 POLA2 PRKDC TRRAP RAD54L MCM3 DNAJC9 SSBP1 GOT2 PMEL SPAG5 KXD1 DNMT1 SNRPA LMNB2 SSRP1 TCEA1 DNAJC11 MCM6 MCM5 SRSF1 TXNL4A TCERG1 SNRNP200 VDAC3 ZNF131 MRPS27 CLPP TNPO3 SAFB CS XRCC5 NAE1 LRPPRC EBNA1BP2 STMN1 PPM1G KHSRP BUB3	up	**
MODULE_205	0.0000247	0.0002616	0.5756103	0.3604205	1.686498	255	KIF1A DKK1 PRLR TF CDHR2 EGLN3 MDM1 CYP19A1 HJURP SPOCK1 NEK2 CIB2 DNAJC22 MUC16 SRGAP3 SLC25A21 DEPDC1B E2F8 KIF14 TRAIP SAYSD1 TPX2 ZNF117 GALNT10 HPS3 DTL KHDC1 ASPHD2 B4GALT4 RSPH1 TTLL4 BOD1 MAP10 SEMA6C HHAT MSX1 ICA1 FANCD2 GPSM2 CDC25C YEATS2 KCNJ11 C22orf46 FDXR WNT5B TSHR KIAA0556 DNER PPM1E DNAH6 CACHD1 FAM114A1 ULBP2 NARF TRAF5 PLVAP IFT52 MYO19 ST14 DLGAP5 SLC26A2 EPHB2 CENPQ AGPAT5 SPA17 CCDC51 COG4 FKBP14 GNAZ SEC14L2 TCTN1 FANCM TIAM2 CELF4 FCHSD1 PRSS16 TMEM45B CNTN2 ZNF286A INTS8 SUV39H2 B9D1 CCNA2 ZNF93 SHCBP1 PPFIA3 ATG4D FBN2	up	***
MODULE_321	0.0006809	0.0054596	0.4772708	-0.3396648	-1.682107	103	LRRC8C PTPRE CD44 CORO1C FOSL1 TGFBR2 ITGA5 ANXA5 KLF6 BTG3 GMEB1 FABP5 YBX3 ACSL3 CCND2 ACTG2 CLIP4 PROCR KANK1 SERPINB8 IFNGR1 FERMT2 LPCAT2 TNFRSF10B RRAS CTNNAL1 APLP2 LTBP1 EPHA2 SOAT1 CTSC NRP2 NRG1 CREG1 EHD4 CNN2	down	**
MORF_CCNF	0.0023228	0.0147626	0.4317077	0.4280788	1.681140	70	TRIP13 FANCI BRCA1 GTSE1 CENPA CCNF WDR62 MKI67 HLTF LARS2 MAD2L1 PPP5C DNA2 OARD1 TTI1 KPNB1 FANCG ANP32E PLEKHB1 CDC7 CPSF4 RRP9 UBE2V2 RFC5 LPGAT1 BMS1 ARHGAP11A PAXIP1 TIMM44 SIGMAR1 NELFA	up	*
MORF_GSPT1	0.0071223	0.0368130	0.4070179	0.4661219	1.678911	43	CCNB1 GGCT CDK4 EIF3B CCT5 SSBP1 ATIC UNG LARP1 FEN1 VBP1 CDC23 PRMT1 ALG8 VDAC1 UBAP2L EIF4G1 MTHFD1 SF3B2 RNF126 TOMM40 NHP2 HNRNPAB ACOT7 PPM1G	up	*
MORF_FANCG	0.0003595	0.0030541	0.4984931	0.3790682	1.673194	144	DDX11 SLC2A1 ECE2 SLC4A3 RBBP8 CCNF PVT1 HAUS5 WDR62 MKI67 BPHL CARD10 TPR MSX1 ERAL1 CDC25C PKMYT1 HSF4 FDXR PPP5C PHB PML ERCC2 MEA1 PPIL2 DNA2 OARD1 TTI1 ZNF500 DNAJC7 FANCG SPEF1 KDM3B CDK13 SH2B1 TSTA3 CPSF4 SRRT TFAP4 NUP62 NFRKB ACKR2 BMS1 PAXIP1 RPRD2 CHD3 ADAM15 PWP1 PLIN3 ILVBL MOK PRKAG1 GRIP2 XPO6 PCGF2	up	**
MODULE_223	0.0005503	0.0044971	0.4772708	-0.3318863	-1.667639	113	EREG IL1A IL1B EMP2 INSIG1 LY86 FOSL1 ADRA1D GAS6 LILRB3 CD8A DNAJC3 CD5 HBEGF KLF6 GRN ZEB1 MTHFR PDGFA DAB2 SELL SELP EVI2A BTG1 EMP3 CD8B AREG IL6 CD48 CD83 OSM CXCL5	down	**
MORF_RRM1	0.0016899	0.0110685	0.4550599	0.4074491	1.662849	86	CENPF ESPL1 MCM2 TYMS ZWINT RUVBL2 NUDT1 CHAF1A BUB1 CCT5 PRKDC RAD54L KIF11 MCM3 DNAJC9 PARP1 SSBP1 GOT2 PMEL FEN1 SPAG5 DNMT1 DLGAP5 SNRPA LMNB2 SSRP1 MCM6 SRSF1 TXNL4A MSH2 VDAC1 SNRNP200 CHERP GPN1 SAFB CS XRCC5 NAE1 LRPPRC STMN1 PPM1G KHSRP BUB3	up	*
MODULE_17	0.0000121	0.0001369	0.5933255	0.3473953	1.658157	314	TRIP13 DDX11 CDC45 PRSS2 CCNB1 IGF2BP3 PSPH DDIT4 SORD TTK KIF14 GMPS NDUFS6 PLK1 AURKB PTTG1 AKR1C1 TPX2 CCNB2 MCM2 TYMS ORC1 CCT6A SRPK1 SHMT2 ZWINT HMMR NUDT1 CHAF1A GFPT1 EEF1E1 TOP2A CBX3 NDUFS2 POLD2 SNCG KIF2C MCM7 PRKDC MRPL3 MCM3 AIMP2 MDK CD24 CDC42EP1 AHCY PSMD4 PKMYT1 CAD PES1 TMED3 KRT18 CDK1 SSBP1 UCK2 ATIC RBCK1 FEN1 EZH2 NUP205 MRPS12 PSMC4 ITPR3 RNASEH2A RANGAP1 DNMT1 VBP1 LMNB2 MBD4 DPH2 TK1 DTYMK DAP3 ASNS SLC4A2 KRT19 LTBR CHPF P4HA1 KLHDC3 CKAP5 CDC20 IARS2 AHCYL1 RRP9 BCL2L1 MCM6 LSM7 TFAP4 RCC1 CCNG1 SLC1A5 SF3A2 ALG8 PYCR1 MSH2 CCNA2 SMARCA4 RBM42 PRIM1 BLVRB BMS1 SEC13 HOXB2 TRIB2 MTHFD1 DHRS3 PAICS APEX1 MRPS27 SNRPC NNMT PPP2R5D NUP93 CALU TRPC4AP TRAPPC6A CYB5B APOBEC3B MLLT11 POLRMT INPPL1 ITGB5 MRPL12 PRPF19 TMEM259 LPCAT1 CLPP APRT	up	***
MORF_PRKDC	0.0002946	0.0025529	0.4984931	0.3692216	1.657754	161	TRIP13 RUVBL1 BUB1B MCM2 TYMS SRPK1 SHMT2 ZWINT RUVBL2 NUDT1 SMARCC1 CHAF1A CCT5 PRKDC TRRAP RAD54L MCM3 ACTL6A PKMYT1 CAD ALG3 COQ9 THOP1 CDKN2C ANAPC5 PABPN1 SSBP1 GOT2 NPM3 KXD1 DNMT1 ILF2 SNRPA SSRP1 MLEC TCEA1 DNAJC11 PSMD2 CDC7 BRD8 MCM6 MCM5 TFAP4 AATF TXNL4A NUP62 PRPF31 BMS1 SNRNP200 VDAC3 ZNF131 RPN1 MRPS27 GPN1 MZF1 AKR7A2 XPO6	up	**
GNF2_CD53	0.0062520	0.0337371	0.4070179	-0.4004513	-1.652205	44	MYD88 LCP1 OSTF1 LAPTM5 PTPRC SELL ACTR3 CD53 ARHGDIB ACTR2 CD48 RAC2 RPS6KA1 PHF11 MFNG PAK2 FXYD5 CRLF3 CYTIP B2M DOCK2 HCLS1 LSP1	down	*
MORF_CSNK2B	0.0001037	0.0009668	0.5384341	0.3519322	1.644033	246	PDCD6 COA1 GGCT CDK4 GMPS GPI ESPL1 EIF3B CCT2 DCTN2 RUVBL2 SDHA EEF1E1 CCT5 CBX3 NDUFS2 MCM7 FBL COMMD4 ANAPC5 HDGF SSBP1 AP3D1 CCT3 ATIC KIF2A LARP1 FEN1 KXD1 SNRPE DAP VBP1 UQCRFS1 CDC23 SNRPA LMNB2 TUBB2A HDAC1 TCEA1 CLTA DAP3 SLC4A2 JTB CCT7 ACLY PRMT1 TMEM147 SRSF1 HAX1 POLR2I SLC1A5 LSM4 PSMB4 SF3A2 EIF3K ALG8 NDUFV1 AP2S1 RER1 GLO1 ATP6AP1 DOCK3 BANF1 VDAC1 SNRPD2 PDAP1 PRPF31 UQCRC1 SEC13 COX5B MRPL9 SRP9 SNRNP200 ACP1 TMED9 NDUFS8 UBAP2L EIF4G1 CHERP TBL3 PTOV1 GPN1 SF3B2 COX6B1 MAP2K2 LYPLA1 COPE AKR7A2 DRG1 DGUOK FAM120A CLPP HUWE1 NHP2 CS SEC24C HNRNPAB SRSF9 PPP2R1A CALM3 COX6A1 DDX49 MAEA FIBP XRCC6 PSMD8 ACOT7 COX6C PRRC2C PPM1G BUB3 ATXN10 HNRNPUL1 RAC1 TRIM28	up	***
MODULE_139	0.0037614	0.0219542	0.4317077	0.4147146	1.636726	73	MNX1 PRLR BDH1 PRR15L AGR2 SPINT2 SYT12 TJP3 SYTL2 FOXA1 MSX2 ICA1 SLC9A3R1 B3GNT3 KRT18 TNFRSF25 ARHGEF16 PKP3 MSI2 KRT19 ERBB3 UBXN6 KRT8 ANXA9 EPCAM CDH1 BLVRB	up	*
MODULE_27	0.0000078	0.0000926	0.5933255	-0.2896894	-1.635045	281	RAMP3 TEK OLR1 ASGR1 EDNRB PPARG SFRP4 TIE1 GPR65 PTPRE THBD FOLR1 FCER1A CALCRL ADCYAP1R1 C5AR1 TGFBR3 IGSF6 LILRB3 CD8A TNFRSF8 PTPRM CD5 HBEGF LIFR CHRNE ITGA5 ANPEP PRSS12 ADRB1 ADRB2 IL18R1 EPOR PTPRO GPA33 PTAFR PLAUR MPL NPR3 CDKN1A ITGAX PTPRC SELP AXL FCER1G CD300C EVI2A IL7R PTH1R PDK4 CD8B HCAR3 CD80 IL2RB PRPH2 HRH1 IFNGR1 GPR183 PTGER2 UNC13B GPRC5A GRIK1 GPR37L1 KLRC2 CR1 ITGA9 GLRA3 CD6 FPR2 CD86 CNTNAP1 GLRA1 LGALS3 CCR1 FCGRT RXRA ICAM1 CXCR4 EPHA4 CCR9 EPHA2 ADORA2A KIT CD3G KLRK1 GPR171 P2RX1 FGFR1 RORA LDLR LPAR6 MS4A2 CSF2RB GHR CNR2 NR4A2 CX3CR1 PRKCH ITGAL	down	***
MODULE_180	0.0024156	0.0152396	0.4317077	0.3822711	1.629525	110	MNX1 TSPAN8 PRLR BDH1 PRR15L AKR1C1 AGR2 SPINT2 GRB7 SYT12 TJP3 MAP7 SYTL2 FOXA1 MSX2 ICA1 HOOK1 MDK SLC9A3R1 B3GNT3 MSI1 LRRC37A4P KRT18 LRRC4 ARHGEF16 LLGL2 MSI2 MMP7 KRT19 ERBB3 UBXN6 KRT8 ANXA9 SSH3 ANK3 EPCAM CDH1 BLVRB	up	*
MORF_BUB3	0.0001430	0.0012917	0.5188481	0.3478886	1.614855	234	GMPS AURKB ESPL1 MCM2 TYMS XPOT ZWINT CCT2 RUVBL2 NUDT1 CHAF1A SDHA BUB1 CCT5 CBX3 NDUFS2 POLA2 MCM7 PRKDC MCM3 DNAJC9 ACTL6A FBL CAD THOP1 ANAPC5 SSBP1 CCT3 GOT2 PMEL FEN1 KXD1 SNRPE RANGAP1 DNMT1 VBP1 ILF2 SNRPA LMNB2 SSRP1 HDAC1 TCEA1 DAP3 DNAJC11 CCT7 BRD8 ACLY MCM6 MCM5 LSM7 SRSF1 HAX1 AATF POLR2I SLC1A5 LSM4 TXNL4A SF3A2 EIF3K NDUFV1 GLO1 MSH2 DOCK3 VDAC1 PRPF31 UQCRC1 MRPL9 SNRNP200 ACP1 TMED9 UBAP2L VDAC3 PAICS CHERP MRPS27 GPN1 SF3B2 MAP2K2 LYPLA1 AKR7A2 DRG1 DGUOK SRM CLPP TNPO3 SAFB EDC4 CS SEC24C XRCC5 NAE1 HNRNPAB LRPPRC SRSF9 PPP2R1A CALM3 DDX49 FIBP XRCC6 STMN1 PSMD8 PPM1G KHSRP BUB3 ATXN10 HNRNPUL1 TRIM28	up	**
MORF_UNG	0.0052796	0.0292250	0.4070179	0.4170503	1.612513	62	PDCD6 CDK4 EIF3B CCT2 CCT5 MRPL3 AIMP2 TMEM106C SSBP1 CCT3 ATIC UNG FEN1 VBP1 CDC23 RPA1 PRMT1 SRSF1 POLR2I ALG8 MSH2 DOCK3 BANF1 VDAC1 EIF4G1 MTHFD1	up	*
MORF_FBL	0.0010775	0.0077044	0.4550599	0.3731306	1.611206	123	COA1 AURKB GPI MCM2 EIF3B CCT2 NME1 RUVBL2 NUDT1 EEF1E1 CBX3 MCM7 AHCY FBL ANAPC5 HDGF SSBP1 CCT3 KXD1 SNRPE ILF2 UQCRFS1 SNRPA JTB CCT7 PRMT1 TMEM147 LSM7 POLR2I LSM4 SF3A2 EIF3K NDUFV1 DOCK3 BANF1 SNRPD2 PDAP1 MRPL9 TBL3 LYPLA1 CLNS1A DRG1 CS HNRNPAB SRSF9 PPP2R1A DDX49 FIBP XRCC6 PSMD8 HNRNPA1 PPM1G BUB3 ATXN10 HNRNPUL1 TRIM28 TARDBP PCNA NCL SNRPB PARK7 CDC123 UBA2 YWHAQ BTF3	up	**
MORF_MTA1	0.0032589	0.0195534	0.4317077	0.3917199	1.608722	88	COIL GGCT XPOT DCTN2 SDHA ACTL6A CNOT3 TMEM106C PABPN1 ILF2 SNRPA TCEA1 SLC4A2 RPA1 MRPL28 POLR2I PSMB4 NUP62 NDUFV1 DOCK3 BANF1 PDAP1 FBXW11 MRPL9 SRP9 SNRNP200 UBAP2L PWP1 ILVBL SART3 MAP2K2 PRKAG1 LYPLA1 AKR7A2 XPO6 DRG1 FAM120A SHMT1 CS HNRNPAB PPP2R1A FIBP PPM1G RAC1 ENSA ARF3 PIGC HDAC2 NCBP2 SMG7 KDELR1 CTDNEP1 COX5A CANX	up	*
MODULE_52	0.0000160	0.0001760	0.5756103	0.3305592	1.599706	368	RIBC2 TRIP13 PLAT FOXM1 SPOCK1 CDC45 PAX9 BUB1B PROM1 PRSS2 CCNB1 CENPF IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 SORD TTK GTSE1 GMPS SPP1 MMP1 PLK1 CENPA PTTG1 ESPL1 TPX2 E2F3 CCNB2 MCM2 UMPS MYBL2 CCNF CCT6A SRPK1 ZWINT TNC CASP2 HMMR NUDT1 CHAF1A PRB4 EEF1E1 TOP2A SEMA6C AGT MYO10 CARD10 POLD2 MSX1 RRM2 SLC22A18AS KIF11 MCM3 LMNB1 SOX4 MDK RBP1 CD24 SLC9A3R1 MAD2L1 SCAMP5 PKMYT1 FDXR FADS2 CLDN9 MGLL PON2 TMED3 CDKN2C TMEM106C PLOD2 KRT18 CDK1 FAT1 UCK2 E2F1 UNG STEAP1 PEG10 FEN1 EZH2 NUP205 ETFB IGSF3 CBX1 DDT ITPR3 RNASEH2A TBX1 LGR5 DLGAP5 CHST3 ALDH7A1 LMNB2 COL5A2 DTYMK DBN1 ASNS KRT19 FHL2 LTBR TYRO3 MAT1A CHPF KLHDC3 CKAP5 CDC20 RRP9 CXCL1 MCM6	up	***
MODULE_8	0.0000440	0.0004289	0.5573322	0.3288020	1.596747	378	HMGA2 TRIP13 FOXM1 LAD1 BUB1B PROM1 CCNB1 CENPF IGF2BP3 PAIP1 PSPH SORD TTK GMPS BAMBI NDUFS6 PLK1 AURKB PTTG1 TPX2 E2F3 CCNB2 MCM2 TYMS UMPS PAH CCT6A SRPK1 SHMT2 ZWINT MYL6B COX11 DNPH1 NUDT1 CHAF1A EEF1E1 TOP2A SEMA6C AGT CBX3 NDUFS2 POLD2 MCM7 CPD PRKDC MRPL3 MCM3 BLOC1S1 LMNB1 AIMP2 SOX4 MDK RBP1 CD24 SLC9A3R1 CDC42EP1 MAD2L1 AHCY PSMD4 CAD ETFA PES1 PON2 TMED3 TMEM106C PLOD2 KRT18 CDK1 SSBP1 FAT1 UCK2 ARPC1A RBCK1 UNG PEG10 FEN1 NUP205 FADD ETFB CBX1 DDT PSMC4 ITPR3 DNMT1 VBP1 ADNP AGL LMNB2 MBD4 COL5A2 ASGR2 TK1 DTYMK DBN1 VIL1 DAP3 ASNS SLC4A2 KRT19 ENPP2 CKAP5 CDC20 IARS2 RPA1 CXCL1 MCM6 KIF21B LSM7 TFAP4 RCC1 PDIA4 SLC1A5 ALG8 EPCAM MSH2 CCNA2 SMARCA4	up	***
MORF_RAD54L	0.0043467	0.0248633	0.4070179	0.3901096	1.595979	87	TRIP13 BUB1B MCM2 SRPK1 ZWINT RUVBL2 CHAF1A PRKDC TRRAP RAD54L ACTL6A PKMYT1 CAD ALG3 THOP1 PABPN1 SSBP1 GOT2 DNMT1 SSRP1 MLEC KIF20B DNAJC11 CDC7 NUP62 BMS1 VDAC3 ZNF131 MZF1 XPO6 TNPO3 SAFB CS NAE1 LRPPRC	up	*
MODULE_126	0.0013469	0.0092452	0.4550599	0.3509869	1.577721	160	FOXM1 BIK CCNB1 CENPF POLQ UBE2T PTPRN2 CDK4 GMPS ASPM TPX2 CMYA5 CDC25A UMPS EIF3B SHMT2 MELK MKI67 BUB1 AURKA SIDT1 PPP5C MGLL CKS1B NCAPG2 MB CDK1 HDGF TNFRSF21 ULBP2 PANX2 E2F1 UNG FEN1 DAP ILF2 EDEM3 ETV4 ANKRD6 IARS2 PRMT1 RCC1 WDYHV1 CCNA2 SLC2A5 NME4 CDK5 CLEC11A SMC2 CENPE TCF3 PAICS TIMM44 APEX1 NOMO1 RCN2 PDXP ITGB5 ASPH GCC2 ADSL CLPP FBXO5	up	**
MODULE_121	0.0027819	0.0172700	0.4317077	-0.3326502	-1.571781	82	IL1A IL1B INSIG1 FOSL1 GAS6 CD8A ERG CD5 HBEGF KLF6 GRN ZEB1 PDGFA DAB2 EVI2A MAPRE2 BTG1 EMP3 CD8B AREG IL6 OSM RUNX3 CD86 CD81 IL18 BCAT1 EDN1 TNFSF9 CREG1	down	*
GCM_MAP4K4	0.0008403	0.0062697	0.4772708	-0.2958724	-1.570084	162	RDX CLDND1 CCDC88A KIAA1109 BMPR2 ARL8B AGPAT4 ZEB2 DNAJB14 UBL3 TTL SPIRE1 TTYH2 ABHD6 EPB41L2 LRP4 ADO RMDN3 SPAG9 PEAK1 FMNL2 IL17D GZF1 RNF141 HMBOX1 PHF10 DDX17 MAP4K4 IPO7 FRYL PDZD2 NAA30 OCIAD1 CALM1 NAPG DDHD2 MTMR2 PPIG WBP2 STX12 NPTN CLASP2 MACF1 PHLPP2 GLTP RTN4 TMOD2 SIK3 IPO5 ULK2 CCDC92 MTUS1 KIF1B RNF13 TMEM30A HIPK1 SH3GLB1 DYNC1I2	down	**
MORF_MSH2	0.0095553	0.0465819	0.3807304	0.4151977	1.564436	54	MCM2 RANBP1 RUVBL2 CHAF1A CCT5 TRRAP AIMP2 ACTL6A SSBP1 UNG ILF2 SSRP1 RPA1 SRSF1 POLR2I ALG8 MSH2 SNRNP200 PARG GPN1 SART3 CLNS1A MSH6 NAE1 HNRNPAB LRPPRC	up	*
MORF_EI24	0.0057736	0.0317548	0.4070179	0.3626203	1.559035	114	TRIP13 CCNB1 XPOT ZWINT RUVBL2 SDHA BUB1 CCT5 NDUFS2 PRKDC ACTL6A ALG3 COQ9 TMEM106C SSBP1 CCT3 GOT2 LARP1 KXD1 VBP1 SNRPA SSRP1 MLEC TCEA1 DNAJC11 TM9SF4 SRSF1 HAX1 POLR2I SLC1A5 LSM4 ALG8 NUP62 NDUFV1 AP2S1 GLO1 DOCK3 VDAC1 SNRNP200 TMED9 VDAC3 EIF4G1 SART3 LYPLA1 AKR7A2 DGUOK FAM120A CS SEC24C HNRNPAB CALM3 PPM1G KHSRP BUB3 ATXN10 RAC1 RFC4	up	*
MORF_FDXR	0.0012350	0.0085454	0.4550599	0.3389389	1.554520	188	DDX11 FUT6 CYP19A1 PAX9 SLC2A1 ECE2 GPR35 COLQ SLC4A3 RBBP8 ALDOC PVT1 IKBKE HAUS5 WDR62 CASP2 BPHL SPTB CARD10 TPR MSX1 ERAL1 PKMYT1 HSF4 FDXR PPP5C PHB PML GLE1 ERCC2 PPIL2 DDX51 TNFRSF25 TTI1 ZNF500 TBX1 FANCG SPEF1 CDK13 PLEKHB1 SH2B1 DHRS1 CPSF4 DGCR11 WNT10B PRSS16 CYP4F12 IGHMBP2 MUSK CNTN2 NFRKB RFC5 TUBGCP4 ACKR2 PAXIP1 CHD3 ADAM15 KHNYN ILVBL MOK CYP11A1 GRIP2 NELFB CAMK2G TLN2 TUBGCP2 LTK HMG20B NCKIPSD RPS6KB2	up	**
MODULE_90	0.0034783	0.0205819	0.4317077	0.9240702	1.547921	3	CENPA CHAF1A CHAF1B	up	*
MODULE_105	0.0014588	0.0098554	0.4550599	0.3365007	1.542131	184	SAA1 FOXM1 LAD1 NEK2 CCNB1 IGF2BP3 CENPA UMPS MYBL2 CCNF GPX2 MELK CHAF1A MKI67 KNTC1 PAFAH1B3 TPBG POLD2 MAD1L1 COASY RRM2 AIMP2 SOX4 EMG1 RBP1 TOPBP1 MAD2L1 PFKP BLM PHB CKS1B SUPT5H CDK1 BIRC5 ARPC1A GOT2 COL3A1 CDH3 EZH2 FADD DAP ITPR3 TUBG1 CCL21 COG2 COL5A2 DTYMK MGMT ASNS S100A13 FXYD3 LTBR P4HA1 RPA1 POLR2J COMP CACNB3 PFKFB4 CBR1 MSH2 CCNA2 FAM3C	up	**
MORF_RAGE	0.0066305	0.0351173	0.4070179	0.3556920	1.526434	116	DDX11 PAX9 SLC2A1 ECE2 GPR35 COLQ SLC4A3 RBBP8 ALDOC PVT1 HAUS5 WDR62 CASP2 BPHL SPTB CARD10 MSX1 HSF4 FDXR PML TNFRSF25 ZNF500 FANCG SPEF1 TSPO2 SH2B1 DGCR11 PRSS16 GGT5 IGHMBP2 MUSK CNTN2 NFRKB TUBGCP4 ACKR2 ADAM15 KHNYN MOK CYP11A1 GRIP2 TLN2 LTK NCKIPSD RPS6KB2 RBM8A CRCP	up	*
MORF_SOD1	0.0009297	0.0068178	0.4772708	0.3281532	1.526189	236	PDCD6 CCNB1 COA1 GGCT CDK4 EIF3B XPOT CCT2 DCTN2 NME1 RUVBL2 SDHA EEF1E1 CCT5 CBX3 NDUFS2 MRPL3 AIMP2 FBL ETFA TMEM106C ANAPC5 SSBP1 CCT3 ATIC UNG SEC61G KIF2A LARP1 FEN1 KXD1 SNRPE DAP VBP1 ILF2 CDC23 SNRPA SLC4A2 CCT7 STOML2 ACLY RPA1 TBCA PRMT1 TMEM147 SRSF1 HAX1 POLR2I LSM4 PSMB4 NEDD8 ALG8 NDUFV1 AP2S1 GLO1 MSH2 DOCK3 BANF1 VDAC1 PRPF31 ATOX1 TPGS2 SEC13 FBXW11 MRPL9 SRP9 SNRNP200 NDUFS8 UBAP2L MTHFD1 CHERP TBL3 GPN1 SF3B2 SART3 MAP2K2 LYPLA1 CLNS1A AKR7A2 DRG1 DGUOK UTP18 FAM120A HUWE1 NHP2 CS HNRNPAB LRPPRC SRSF9 PPP2R1A CALM3 COX6A1 DDX49 FIBP PSMD8 ACOT7 COX6C PPM1G BUB3 ATXN10 RAC1 TRIM28	up	**
GCM_ZNF198	0.0083556	0.0424205	0.3807304	-0.3034034	-1.518084	108	HEATR5B PAFAH1B2 FBXO3 PDCL SYNC NLK KANK2 EPM2AIP1 HNRNPU CCDC82 ACSL3 ZFAND5 SPAG9 CLK4 KPNA3 CREBRF PRKRA CRNKL1 CELF1 NAA30 TUBGCP3 EPC2 FOXO3 CEP76 NAB1 CNOT7 HNRNPH3 PHF2 SMAD2 CEP170 FBXO30 MEX3C MED17 RABGEF1 HIPK1 FAM8A1 DYNC1I2 KMT2E UBE2N KIDINS220	down	*
GCM_DLG1	0.0069208	0.0359880	0.4070179	-0.3301942	-1.511753	69	RAPGEF2 CLDND1 KIAA1109 PLEKHA1 ARL8B EPB41L3 DNAJB14 ABHD6 EFCAB14 MOAP1 MAP4K4 FRYL OCIAD1 NAPG DDHD2 ATG2B FAXDC2 NPTN PHLPP2 GLTP RTN4 IQSEC1 SIK3 IPO5 CCDC92 RNF13	down	*
MODULE_79	0.0089804	0.0447974	0.3807304	-0.3178352	-1.510157	86	DLC1 CYP27A1 LMO2 NXPH3 CDH13 GAS6 IFI30 DES DAB2 THBS1 VIM CCND2 FCER1G VWF IL2RB KCTD12 TYROBP CD151 TNFSF13 TIMP2 CCR1 GATA6 CEBPD S100A4 DAPK1 TIMP3 LYZ FTL FPR1 ZNF347 IL32 CYP1B1 MYLK C3AR1 GZMK TNFAIP6 PDGFRA CCL18 CCR5 IL1R1	down	*
MODULE_197	0.0068218	0.0357638	0.4070179	0.3376788	1.501711	149	DDX11 FOXM1 TFAP2A CCNB1 NPAS1 NDC80 TBRG4 CDK4 PLK1 PTTG1 SOX9 E2F3 CCNB2 RBBP8 CDC25A MYBL2 NCAPD2 KIF23 KNTC1 BUB1 KIF2C WDHD1 HOXC6 MCM3 SOX4 ACTL6A MAD2L1 PPP5C TULP3 CDK1 BIRC5 E2F1 EZH2 CBFA2T2 DNMT1 CCNE1 CDK3 KIF22 SSRP1 NFATC4 CDC7 CXCL1 MCM6 NEK4 RCC1 TXNL4A PMS1 CCNA2 ZNF195	up	*
MORF_DDX11	0.0051417	0.0286466	0.4070179	0.3434443	1.500053	135	DDX11 SLC2A1 ECE2 GPR35 RBBP8 ALDOC PVT1 HAUS5 WDR62 CASP2 BPHL SPTB CARD10 TPR MSX1 GCAT PKMYT1 HSF4 FDXR PHB PML PPIL2 TNFRSF25 TTI1 HMGXB3 ZNF500 FANCG SPEF1 TSPO2 CDK13 SH2B1 CPSF4 DGCR11 WNT10B PRSS16 IGHMBP2 CNTN2 MCRS1 NFRKB ACKR2 CHD3 ADAM15 PLIN3 KHNYN MOK NELFB TLN2 LTK HMG20B NCKIPSD RPS6KB2 RBM8A CRCP	up	*
MODULE_26	0.0046067	0.0261758	0.4070179	0.3332779	1.498782	163	CPNE4 CDHR2 BBOX1 MDM1 ZDHHC4 PRTFDC1 UBE2T FA2H MSTO1 CYP46A1 SLC7A9 DYNC1I1 KHDC1 STRA6 RPAP1 EMC9 MAP3K13 TFR2 B3GNT3 TRIT1 MYOT MRPL36 APLP1 FAHD2A LINGO1 SERTAD4 CENPJ TYW1 RBCK1 TRIM2 ACTR3B SMO NLN GDAP1L1 ZKSCAN5 IFT52 HSPA4L	up	*
MORF_AATF	0.0031965	0.0193140	0.4317077	0.3267948	1.497650	184	RUVBL1 EIF2B5 MCM2 CCT2 RUVBL2 SDHA TP53BP1 PRKDC TRRAP AIMP2 ACTL6A PKMYT1 CAD PHB ALG3 COQ9 DYRK2 THOP1 ANAPC5 PABPN1 SSBP1 KXD1 RTCB EIF6 ILF2 MTOR SNRPA SSRP1 MLEC TCEA1 DAP3 DNAJC11 KDM3B PSMD2 COPS6 PSMB3 BRD8 ACLY SRRT MCM5 LSM7 TFAP4 AATF POLR2I SMARCC2 EIF3K NUP62 PRPF31 BMS1 MRPL9 SNRNP200 VDAC3 RPN1 GPN1 PWP1 SART3 PRKAG1 LYPLA1 CLNS1A XPO6 DRG1 NELFB ADSL HUWE1 SAFB CS XRCC5 NAE1 HNRNPAB LRPPRC PSMD3 DHX38 DDX49 FIBP	up	*
MODULE_15	0.0000961	0.0009065	0.5384341	-0.2636183	-1.497329	295	TNR CD52 PECAM1 HHEX GATA2 IL1B LIPA INSIG1 CD44 LMO2 DYRK1A ELMO1 ANXA1 MAN2B1 ADA RAP1A EIF5 ANPEP SLC7A11 LCP1 LAIR1 SRSF2 SRGN TFRC APOC1 CD37 ZMIZ1 PTPN12 EVI2B MAP2K3 SCP2 BIRC2 BNIP2 GPA33 LAPTM5 PTPRC CXCL2 ATF3 SELL HOPX PNRC1 CCND2 M6PR CD53 PLEK VAMP5 HLA-DQA1 MAFF ARHGDIB EMP3 SERTAD2 ARL6IP5 S1PR4 METAP1 NSMAF COPS2 JUN RAC2 PLK3 JUNB RHOG PPP1R15A WTAP GMFG RAB8A TNFRSF10B CLN3 CST7 CD34 PLCG2 FOS PTP4A1 FOSB MME IRF5 TGFB1 SERPINB1 EWSR1 PIM1 ORM2 RGS2 CLEC2B ETS2 ME2 MBNL1	down	***
MODULE_181	0.0058181	0.0317958	0.4070179	0.3234468	1.481482	186	RIBC2 TP63 ENTPD2 POM121L9P FAT2 NRG2 FUT3 ECE2 GTSE1 PROC TBX19 CYP27B1 CCNF HBB RUNDC3A AOC1 CASP2 SMAGP PRB4 SLC29A2 MPO SLC22A18AS B3GNT3 HPR SCAMP5 GAS8 MSI1 ABCB9 GLE1 CLDN9 PIGO RECQL5 EXOSC2 TNFRSF21 JAKMIP1 ALDOB TBX1 CHST3 GALNS PKP3 MAPK13 RAD51D FZR1 ACSL6 MAT1A DNASE1 WNT10B KIF21B GNG4 LRCH4 MYEF2 UNC119B APC2 CDH1 CCDC9 BRMS1 PPP6R2 KCNQ3 MLLT1 ALOX15 TRPM2 PIGL NELFA	up	*
MORF_PRKAG1	0.0066273	0.0351173	0.4070179	0.3200664	1.469883	193	NIPSNAP1 EIF2B5 TOMM34 CIB1 RUVBL2 SDHA HLTF TP53BP1 BPHL TPR CDC25C ACTL6A PKMYT1 CAD PHB CNOT3 ALG3 COQ9 MEA1 PABPN1 KXD1 OARD1 RTCB DNAJC7 GOLGA3 FANCG ILF2 MLEC TCEA1 DAP3 SLC4A2 KDM3B PSMD2 COPS6 P4HA1 SH2B1 TSTA3 CPSF4 BRD8 AHCYL1 SRRT MRPL28 TFAP4 AATF NUP62 DOCK3 NFRKB CSNK1G2 BMS1 FBXW11 MRPL9 SNRNP200 RPRD2 CHD3 PARG ADAM15 PWP1 PLIN3 ILVBL SART3 MZF1 PRKAG1 PARP2 CYHR1 XPO6 DRG1 NELFB HUWE1 NSL1 MPST CS LRPPRC UBE3C PSMD3 PPP2R1A PDXDC1 DRAP1 BECN1 CLTC PMM2 RAC1 DDB1 ATXN2L YIF1A PIGC PRKCSH POLR2C SUMO4 CLSTN1 RPN2 HDAC2 NCBP2	up	*
MORF_DAP3	0.0068360	0.0357638	0.4070179	0.3207783	1.456183	170	NIPSNAP1 EIF2B5 CCT2 RUVBL2 SDHA CBX3 ZNF146 ALG3 ANAPC5 CCT3 KXD1 SNRPE DDT RTCB EIF6 POLR2H ILF2 SNRPA COX7C TCEA1 DAP3 PSMD2 JTB COPS6 CCT7 PSMB3 BRD8 STOML2 AHCYL1 ACLY TMEM147 HAX1 AATF POLR2I PSMB4 SMARCC2 EIF3K NDUFV1 BANF1 PDAP1 COX5B FBXW11 MRPL9 SRP9 SNRNP200 DNPEP TBCB TBL3 GPN1 COX6B1 PRKAG1 LYPLA1 CLNS1A DRG1 DGUOK FAM120A NELFB HUWE1 CS XRCC5 HNRNPAB LRPPRC SRSF9 PPP2R1A COX6A1 DDX49 FIBP PSMD8 IK BUB3 ATXN10 RPP40 HNRNPUL1	up	*
GNF2_HDAC1	0.0102876	0.0498685	0.3807304	-0.2946550	-1.445891	98	SRSF7 TRA2B SRSF2 HNRNPDL HNRNPU SS18L2 CCDC59 RPF1 EXOSC8 RBM39 CDC40 DDX47 SRSF3 SF3B1 PSMA1 DHX15 SLC7A5P1 DDX18 ZBTB1 SRSF4 KHDRBS1 CNOT7 UTP3 MAGOH RNF138 SF1 OSR1 HNRNPK SRSF10 HNRNPC ANKRD49 FNBP1 YTHDC1 SCAF11 SMARCA5 PNRC2 AIMP1 FAM111A SRRM1 NOL11 CBFB UBE2D2	down	*
MODULE_60	0.0007129	0.0056115	0.4772708	-0.2413617	-1.391701	336	EPAS1 CD52 SCN4A HMOX1 CLEC3B RAMP2 CDH5 ENG LPL CITED2 ALAS1 TGFBR2 TRIB1 HSPG2 CD8A FGR PDE2A APOD MAN2B1 HBEGF ACOT2 RNASE1 LAIR1 NR4A1 GNG7 GRN CES1 APOC1 MTHFR CD37 RHOB MAP2K3 CFD TNNC1 EPOR GPA33 GAA TJP1 CLDN5 GMPR CDKN1A KCNMB1 PNRC1 IGFBP2 CCND2 M6PR PRF1 FCER1G PER1 TBX5 WFS1 VAMP5 MYH11 PTGIS MAPRE2 VWF EMP3 KCNA5 CD8B FAM107A S1PR4 AQP3 LAMB2 CYB5R1 FAM189A2 RAC2 CYP2A6 ST6GALNAC4 PLK3 PPP1R15A CRYM MFAP4 FSTL3 CLN3 CST7 CD34 CD151 GJA4 NKG7 TGFB1 PARD6A FPR2 LRRC32 COL15A1 CCR1 FCGRT PLEKHO2 SOD3 GPX3 PDLIM5 HTR6 SPIB TOB2 BCAM IFFO1 RBMS3 S100A4 ICAM3	down	**
MODULE_94	0.0065802	0.0351173	0.4070179	0.2935757	1.391287	296	ALDH3B2 PRLR GRIK2 FUT6 BIK CPLX2 SPOCK1 PRSS2 WFDC2 CYP2J2 NPAS1 PLEKHA6 TFF3 LHB SLC27A2 BCAS1 COL7A1 EFNA4 DIO2 HOXB7 GALNT10 HBB PLS1 ACY1 SPINK1 EPHB1 CDT1 AOC1 CXCL10 ITGA2 SMARCD3 F2RL1 MAP3K13 APOL1 THBS4 ITGB4 KLHL25 C6 ICA1 SLC22A18AS TOM1L1 SYMPK HSPBP1 APLP1 KRT18 STEAP1 STAT2 PMEL ITPKA POLR1C DDT RECQL4 ARNT2 TEP1 QPRT NET1 CCNE1 ATP7B AMPH CCL21 COL9A2 ARHGAP32 DHODH COL5A2 EPHB2 KCNC3 IL15RA TP53TG1 ENPP2 TYRO3 ELAC2 CHPF KLHDC3 PLCH2 KDELR3 HNF1B RRP9 ENTPD3 PEX5 RAI14 SKAP1 CH25H OVOL2 RCC1 KRTAP5-9 ROS1 ADM ME1 SCO2 ABCF3	up	*
MODULE_38	0.0018248	0.0118615	0.4550599	-0.2303929	-1.346981	383	TNR EPAS1 HMOX1 PECAM1 GATA2 CLEC3B EMP2 CYP4B1 RAMP2 CDH5 ENG LMO2 CAV1 CITED2 ADRA1D ALAS1 TGFBR3 FUCA1 HSPG2 FGR HEG1 APOD ANXA1 TBX2 BMP1 PLXNA2 ITGA5 ACOT2 ANPEP RNASE1 SERPINB9 LAIR1 GATA3 GRN MTHFR SLC5A2 RHOB MAP2K3 CFD PTPRO GPA33 KIAA0513 RUNX1T1 DAB2 SLC7A8 CLDN5 GRK5 LAPTM5 CDKN1A ATF3 HOPX IGFBP2 M6PR PER1 WFS1 ACTG2 VAMP5 MYH11 HES1 MAFF CRIM1 PTH1R VWF PROCR EMP3 FAM107A FLT1 SLCO2B1 LAMB2 CYB5R1 ETV3 RAB31 LTBP2 DDX17 PLK3 JUNB PPP1R15A COBLL1 MFAP4 FSTL3 CLN3 CD34 CD151 GJA4 FOSB SMPDL3B TIMP2 TGFB1 SFTPC DUSP5 MMP15 LRRC32 NFYC PIM1 COL15A1 FCGRT PLEKHO2 LTBP1 ETS2 SOD3 HSPA2 GPX3	down	*

C5 GO genes Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
GO_IMMUNOGLOBULIN_COMPLEX	0.0000000	0.0000001	0.8140358	0.6087314	2.377217	69	IGHV4-61 IGHV4-4 IGLV4-69 IGLV3-27 IGKV3D-15 IGKV1-17 IGKV2D-29 IGLV1-36 IGKV3-15 IGKV1-6 IGKV1-16 IGKV1-27 IGLV3-9 IGKV4-1 IGLC7 LIME1 IGKV2D-28 IGLV3-10 IGLV1-44 IGKV1-5 IGKV2-24 IGKV1D-33 IGHV3-48 IGLV1-40 IGKV1-9 IGHG1 IGLV7-43 IGLV6-57 IGHM IGLV1-47	up	***
GO_NEGATIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.0000020	0.0001649	0.6272567	-0.6375721	-2.376934	31	ANGPT4 ACVRL1 PPARG TBXA2R RHOA MIR146A MMRN2 RGCC KLF4 THBS1 MIR24-2 NOTCH1 TGFB1 FGF2 VASH1 STARD13 MIR640 MIR2355 ANGPT2 HMGB1	down	***
GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.0000000	0.0000020	0.7477397	-0.4802116	-2.328150	106	ANGPT4 ACVRL1 HMOX1 SOX18 PPARG ADTRP GATA2 EMP2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 ADAM17 CLEC14A HSPB1 NR4A1 RGCC NFE2L2 AKT3 FOXC2 MAP2K3 STAT5A AMOTL1 KLF4 THBS1 MIR24-2 PIK3C2A NUS1 SRF PRCP NOTCH1 ETS1 RHOJ TGFB1 MIR23A MIA3 FGF2 VASH1 EPHA2 FGFR1 STARD13 GREM1 ITGB1 MIR640 MIR2355 EFNB2 ANGPT2 HMGB1	down	***
GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS	0.0000052	0.0003682	0.6105269	-0.6399382	-2.305111	28	PPARG ADTRP LPL CDH13 MYD88 CD9 CD36 MIR146A ADAM17 ABCG1 SOCS5 TLR4 FCER1G MIA3 CD81 SREBF2 LDLR HMGCS1 ITGB1	down	***
GO_POSITIVE_REGULATION_OF_COAGULATION	0.0000297	0.0015024	0.5756103	-0.6600765	-2.274512	23	THBD TBXA2R CD36 NFE2L2 THBS1 SELP HPSE TLR4 PLEK PSEN1 ENPP4	down	**
GO_MACROPHAGE_ACTIVATION	0.0000001	0.0000144	0.7049757	-0.4881929	-2.262973	78	PLA2G10 C5AR1 IL1RL1 SLC11A1 FOXP1 CD93 GRN SLC7A2 IL10 THBS1 CEBPA CCL3 PTPRC TLR4 IL6 C1QA JUN TYROBP IFNGR1 PRKCE SUCNR1 CST7 TREX1 CD74 JMJD6 FPR2 SYT11 HAVCR2 CTSC RORA LDLR SPHK1 CSF2 TREM2 WNT5A SHPK	down	***
GO_CATALYTIC_ACTIVITY_ACTING_ON_DNA	0.0000000	0.0000000	0.9101197	0.4976925	2.256001	182	HMGA2 DDX11 DDX12P RUVBL1 CDC45 POLQ PIF1 GINS1 DNMT3B POLE RBBP8 MCM4 MCM2 RAD54B MCM8 LIG3 GINS4 SMUG1 NME1 TOP3B RUVBL2 EXO1 POLM TOP2A EME1 POLA2 POLD2 SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 LIG1 EME2 XRCC1 THAP10 DSCC1 BRIP1 BLM ERCC2 RECQL5 POLN TERC POLE2 NAV2 UNG DNA2 NEIL3 FEN1 RECQL4 TEP1 DNMT1 DCLRE1C POLL MBD4 RAD9A CHTF18 MGMT GINS2 CHD5 POLD1 POLB SLX4 DNASE1 RAD50 PGBD5 HMGA1 ALKBH4 MCM6 MGME1 DNMT3A CHTF8 MCM5 TDP1 ZRANB3 IGHMBP2 RTEL1 RFC5 RAD51 N6AMT1 CHD3 MPG NEIL1 APEX1 RAD1 ERCC3 ALKBH2 MUS81 DNASE1L2 TOP3A METTL4 DFFB RAG1 CHD8 DCLRE1B DQX1 DCLRE1A ASCC3 XRCC5	up	***
GO_DNA_DEPENDENT_ATPASE_ACTIVITY	0.0000000	0.0000007	0.7749390	0.5392533	2.254753	97	DDX11 DDX12P RUVBL1 CDC45 POLQ TTF2 PIF1 GINS1 MCM4 MCM2 RAD54B XRCC2 MCM8 GINS4 RUVBL2 HLTF TOP2A SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 MNAT1 RECQL5 NAV2 DNA2 RECQL4 RAD51D CHTF18 GINS2 CHD5 RAD50 MCM6 CHTF8 MCM5 ZRANB3 IGHMBP2 MSH4 MSH2 SMARCA4 RTEL1 RFC5 RAD51 CHD3	up	***
GO_AXONEME_ASSEMBLY	0.0000004	0.0000422	0.6749629	0.6347154	2.254335	42	SPAG17 TTC26 DNAI1 RSPH1 ARMC4 SPAG16 HYDIN TEKT2 CCDC114 DNAH8 GAS8 DNAAF3 CCDC40 DRC1 LRGUK LRRC6 DNAH5 DNAH7 CCDC151 IQCG SPAG1 DNAJB13 TTLL3 DNAI2 RSPH4A DNAH1 ZMYND10 ARMC2 DNAAF1 WDR63	up	***
GO_ENDOCYTIC_VESICLE_LUMEN	0.0000012	0.0001085	0.6435518	0.7872467	2.246334	17	SAA1 LTF HP HBA1 HBA2 HBB MPO	up	***
GO_SISTER_CHROMATID_SEGREGATION	0.0000000	0.0000000	0.8634154	0.4994604	2.239472	163	TRIP13 DDX11 DDX12P STAG3L2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 PRC1 NCAPD2 ZWINT CDT1 SPDL1 KIF23 STAG3 BOD1 BUB1 TOP2A MAP10 REC8 TPR KIF2C MAD1L1 CDCA5 HORMAD1 MAD2L1 DSCC1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 DIS3L2 NCAPG FEN1 SPAG5 MAD2L2 KLHL22 KPNB1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA AKAP8L ESCO2 ANAPC1 CENPK STAG3L4 CDC20 TUBG2 CHMP4C CDK5RAP2 CHTF8	up	***
GO_DNA_HELICASE_ACTIVITY	0.0000001	0.0000104	0.7049757	0.5762280	2.219599	65	DDX11 DDX12P RUVBL1 CDC45 POLQ PIF1 GINS1 MCM4 MCM2 RAD54B MCM8 GINS4 RUVBL2 MCM7 HELB MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 RECQL5 NAV2 DNA2 RECQL4 CHTF18 GINS2 CHD5 RAD50 MCM6 CHTF8 MCM5 IGHMBP2 RTEL1 RFC5 RAD51 CHD3	up	***
GO_POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS	0.0000049	0.0003514	0.6105269	-0.5233744	-2.218575	51	EREG IL1A HMOX1 SPN IL1B TNFRSF8 CLEC7A HSPB1 TRAF6 PTAFR THBS1 PTPRC TLR4 CD80 IL6 PSEN1 TYROBP CD74 CD86 EGR1 WNT5A BCL10 AKAP12 CD3E IRF1 IRF4 CD4 EBI3	down	***
GO_CARDIOBLAST_DIFFERENTIATION	0.0000354	0.0017312	0.5573322	-0.7414115	-2.210341	15	TBX2 WNT3A REST TBX5 TGFB2 SRF RBPJ NOTCH1 MYOCD GATA6 NRG1 GREM1	down	**
GO_DNA_DEPENDENT_DNA_REPLICATION	0.0000000	0.0000001	0.8140358	0.5053599	2.201224	132	DDX11 CDC45 TICRR MCM10 CHEK2 TIMELESS POLQ PRIM2 GINS1 E2F8 DBF4B POLE CDC6 MCM4 MCM2 ORC1 LIG3 GINS4 CDT1 EME1 POLA2 POLD2 SMARCAL1 MCM7 MMS22L WDHD1 HELB MCM3 LIG1 EME2 ORC6 DSCC1 BLM RECQL5 POLN SSBP1 POLE2 RFWD3 GMNN DNA2 FEN1 RECQL4 CCNE1 DNAJA3 CHTF18 GINS2 LRWD1 POLD1 POLB ATAD5 CDC7 STOML2 HMGA1 RPA1 FANCM MCM6 MGME1 CHTF8 WRNIP1 MCM5 ZRANB3 GINS3 PRIM1 RTEL1 RFC5 NUGGC RAD51 PNKP TONSL BCL6	up	***
GO_DNA_REPLICATION_INITIATION	0.0000015	0.0001317	0.6435518	0.6435028	2.196652	34	CDC45 TICRR MCM10 PRIM2 POLE CDC6 MCM4 MCM2 ORC1 CDT1 POLA2 MCM7 MCM3 ORC6 POLE2 CCNE1 LRWD1 MCM6 WRNIP1 MCM5 PRIM1	up	***
GO_ENDOTHELIAL_CELL_DEVELOPMENT	0.0000067	0.0004543	0.6105269	-0.5225625	-2.192976	50	SOX18 PECAM1 IL1B RDX RAPGEF2 CDH5 ENG MYADM HEG1 PDE2A RAP1A PDE4D ROCK2 ROCK1 TJP1 CLDN5 CLIC4 ARHGEF26 ADD1	down	***
GO_CELLULAR_RESPONSE_TO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_STIMULUS	0.0000436	0.0020489	0.5573322	-0.7236746	-2.192590	16	PPARG LPL CDH13 CD9 CD36 SOCS5 FCER1G CD81 SREBF2 LDLR HMGCS1 ITGB1	down	**
GO_MITOTIC_G2_M_TRANSITION_CHECKPOINT	0.0000075	0.0004913	0.6105269	0.6830093	2.177296	25	HMGA2 TICRR BRCA1 BRSK1 CDC6 ORC1 CDK5RAP3 CLSPN TOPBP1 BLM CDK1	up	***
GO_MICROTUBULE_MOTOR_ACTIVITY	0.0000001	0.0000163	0.6901325	0.5431318	2.175542	78	KIF1A KIF12 KLC3 KIF20A DNAH2 KIF18B KIF14 DNAH3 DYNC1I1 KIF27 DNAH14 DNAI1 KIF23 KIF15 KIF3B KIF2C WDR78 KIF11 WDR60 DNAH8 KIF3C DNAH11 DNAH6 KIF5A KIF19 KIF2A KIF7 DYNLL2 DNAH5 DNAH7 KIF22 KIF21A KIF20B KLC2 KLC4 WDR34 DYNC1LI2 KIF21B DNAI2 DYNC2H1	up	***
GO_DNA_CONFORMATION_CHANGE	0.0000000	0.0000000	0.8753251	0.4714249	2.161552	203	HMGA2 DDX11 HELLS DDX12P HJURP RUVBL1 CDC45 CCNB1 POLQ PIF1 GINS1 CABIN1 TSPYL5 CENPA SOX9 MCM4 MCM2 RAD54B MCM8 MIS18A GINS4 SRPK1 NCAPD2 TOP3B RUVBL2 CHAF1A TOP2A CENPL GPER1 TPR SMARCAL1 MCM7 CENPW CDCA5 HELB RAD54L MCM3 CHAF1B CHD6 CENPO DSCC1 BRIP1 BLM ERCC2 MNAT1 RECQL5 PARP1 NCAPG2 NUSAP1 ASF1B CDK1 SSBP1 CENPH NAV2 NCAPG DNA2 RECQL4 CENPP HIRA CHTF18 CENPQ AKAP8L GINS2 NOC2L CHD5 RAD50 CENPK CENPV CENPM HMGA1 RPA1 MCM6 CHTF8 CENPT MCM5 ZRANB3 IGHMBP2 BANF1 RTEL1 RFC5 RAD51 CHMP1A CHD3 SIRT6 SMC2 XPC TP53 NCAPD3 DDB2 SART3 ERCC3 NCAPH ACIN1	up	***
GO_PATTERN_RECOGNITION_RECEPTOR_ACTIVITY	0.0000782	0.0031963	0.5384341	-0.7242210	-2.159091	15	FCN1 MARCO CD36 CLEC7A PTAFR LY96 TLR4	down	**
GO_MITOTIC_SISTER_CHROMATID_SEGREGATION	0.0000000	0.0000015	0.7477397	0.4908123	2.151023	137	TRIP13 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 PRC1 NCAPD2 ZWINT CDT1 SPDL1 KIF23 BOD1 BUB1 MAP10 TPR KIF2C MAD1L1 CDCA5 MAD2L1 DSCC1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 DIS3L2 NCAPG SPAG5 MAD2L2 KLHL22 KPNB1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA AKAP8L ANAPC1 CENPK CDC20 TUBG2 CHMP4C CDK5RAP2 CHTF8	up	***
GO_POSITIVE_REGULATION_OF_PHAGOCYTOSIS	0.0000080	0.0005144	0.5933255	-0.5037726	-2.145774	55	SIRPB1 CD300LF PPARG GATA2 IL1B GAS6 SLC11A1 CD36 RAP1A CLEC7A PTX3 SIRPA PTPRC SFTPD FCER1G LYAR NCKAP1L IL2RB RAB31 RAPGEF1	down	***
GO_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER	0.0000826	0.0033073	0.5384341	-0.5387553	-2.145566	38	SOX18 PECAM1 IL1B RDX RAPGEF2 CDH5 ENG MYADM PDE2A RAP1A PDE4D ROCK2 ROCK1 TJP1 CLDN5 ADD1	down	**
GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_PROLIFERATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0001088	0.0041129	0.5384341	-0.6171394	-2.138503	24	ACVRL1 HMOX1 GATA2 BMPER MIR27B MIR146A NRARP THBS1 MIR24-2	down	**
GO_CONDENSED_CHROMOSOME_OUTER_KINETOCHORE	0.0000022	0.0001852	0.6272567	0.8278907	2.127688	12	BUB1B CCNB1 CENPF NDC80 PLK1 SPDL1 BOD1 BUB1	up	***
GO_TRANSFORMING_GROWTH_FACTOR_BETA_ACTIVATED_RECEPTOR_ACTIVITY	0.0000914	0.0035751	0.5384341	-0.7978916	-2.123506	10	ACVRL1 BMPR2 TGFBR3 TGFBR2 LTBP4	down	**
GO_NUCLEAR_CHROMOSOME_SEGREGATION	0.0000000	0.0000000	0.8513391	0.4599092	2.123062	209	TRIP13 DDX11 SPICE1 DDX12P STAG3L2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ECT2 ESPL1 CDC6 PRC1 NCAPD2 ZWINT CDT1 SPDL1 KIF23 STAG3 BOD1 BUB1 TOP2A MAP10 EME1 REC8 SYCP2 TPR KIF2C MAD1L1 CDCA5 FANCD2 HORMAD1 EME2 MAD2L1 DSCC1 BRIP1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 SUN1 DIS3L2 NCAPG FEN1 SPAG5 TRAPPC12 MAD2L2 KLHL22 KPNB1 CCNE1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA CENPQ AKAP8L ESCO2 ANAPC1 SLX4 ANKRD31 CENPK STAG3L4 MEI1 CDC20 TUBG2 CHMP4C FANCM CDK5RAP2 CHTF8	up	***
GO_DNA_REPLICATION_ORIGIN_BINDING	0.0000153	0.0008979	0.5756103	0.6800740	2.122048	23	DDX11 CDC45 MCM10 CDC6 MCM4 MCM2 ORC1 MCM8 MCM7 MCM3 ORC6	up	***
GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	0.0000072	0.0004763	0.6105269	-0.4494925	-2.120830	83	ACVRL1 TEK ACE DLC1 IL1B WNT4 RAPGEF2 CAV1 CORO1C RHOA APOD RAP1A SFRP1 GPBAR1 ROCK2 SNAI1 DUSP3 LIMS1 ROCK1 TJP1 THBS1 CLDN5 PEAK1 MYO1C FAM107A MAP4K4 RAPGEF1 PRKACA PPM1F EPHA3 CLASP2 MACF1 EPB41L5 EPHA2 LIMCH1 PTEN IQGAP1	down	***
GO_DNA_PACKAGING	0.0000001	0.0000080	0.7195128	0.5019710	2.119393	104	HMGA2 HELLS HJURP RUVBL1 CCNB1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A SRPK1 NCAPD2 CHAF1A TOP2A CENPL GPER1 TPR CENPW CDCA5 CHAF1B CENPO NCAPG2 NUSAP1 ASF1B CDK1 CENPH NCAPG CENPP HIRA CENPQ AKAP8L NOC2L CHD5 CENPK CENPV CENPM HMGA1 CENPT BANF1 CHMP1A SIRT6 SMC2 TP53 NCAPD3 SART3 NCAPH ACIN1 DFFB SMYD3 NPM1 RNF8	up	***
GO_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0000110	0.0006774	0.5933255	-0.4974670	-2.118915	55	HMOX1 ADTRP GATA2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 CLEC14A NR4A1 AKT3 FOXC2 KLF4 THBS1 PIK3C2A SRF NOTCH1 RHOJ MIR23A MIA3 FGF2 STARD13 GREM1 ITGB1 MIR2355 EFNB2	down	***
GO_BLOOD_VESSEL_MATURATION	0.0001100	0.0041445	0.5384341	-0.8555088	-2.110730	8	ACVRL1 CDH5 LYL1 S1PR1 RECK	down	**
GO_NEGATIVE_REGULATION_OF_DNA_REPAIR	0.0000367	0.0017797	0.5573322	0.6673990	2.105106	24	HMGA2 PARPBP POLQ MAGEF1 TP53BP1 AUNIP HELB RECQL5 MAD2L2 UBQLN4 TWIST1	up	**
GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	0.0000028	0.0002213	0.6272567	-0.4465469	-2.104656	84	HHEX IL1B FYN BAIAP2 FGF10 ELMO1 CDC42 NCF2 RHOA MMRN2 TMEM204 ITGA5 HSPB1 FZD4 CRK FOXC2 ROCK2 ROCK1 AXL SH2D2A NCKAP1L FLT1 WASF2 PIK3R1 VAV3 EPN2 HSP90AA1 PAK2 NRP2 GRB10 FLT4 ABI1 CYBA	down	***
GO_DOUBLE_STRAND_BREAK_REPAIR	0.0000000	0.0000001	0.8140358	0.4610325	2.103727	191	HMGA2 TRIP13 DDX11 FOXM1 EYA1 CDC45 PARPBP CHEK2 TIMELESS POLQ BRCA1 NABP2 WDR70 FIGNL1 RBBP8 MCM4 MCM2 RAD54B XRCC2 CIB1 MCM8 LIG3 GINS4 MAGEF1 TP53BP1 POLM AUNIP EME1 REC8 MCM7 MMS22L CDCA5 PRKDC HELB RAD54L MCM3 EME2 CHEK1 RAD51AP1 XRCC1 BRIP1 BLM PML RECQL5 PARP1 POLN RFWD3 DNA2 AP5Z1 FEN1 MAD2L2 RECQL4 DCLRE1C POLL RAD51D ESCO2 MGMT GINS2 NUDT16 POLB PARP9 SLX4 CDC7 RAD50 UBQLN4 PALB2 TWIST1 RPA1 UBE2V2 MCM6 XRCC4 MCM5 TDP1 UIMC1 MSH2 DTX3L RTEL1 RAD51 TNKS1BP1 PAXIP1 NUDT16L1 SIRT6 TONSL SWI5 TP53	up	***
GO_REGULATION_OF_PHAGOCYTOSIS	0.0000030	0.0002325	0.6272567	-0.4550573	-2.099998	77	SIRPB1 CD300LF PPARG GATA2 IL1B GAS6 SLC11A1 FGR CD36 RAP1A CLEC7A PTX3 SIRPA PTPRC SFTPD FCER1G LYAR C4BPB HCK NCKAP1L SNX3 IL2RB APPL1 RAB31 RAPGEF1 ATG3 PRKCG FPR2 SYT11 PTEN ANO6 SPHK1 CYBA TREM2 CALR HMGB1	down	***
GO_CHROMOSOME_CONDENSATION	0.0000349	0.0017248	0.5573322	0.6555859	2.098097	26	HMGA2 CCNB1 NCAPD2 TOP2A GPER1 CDCA5 NCAPG2 NUSAP1 CDK1 NCAPG AKAP8L BANF1 CHMP1A SMC2 NCAPD3 NCAPH ACIN1 DFFB	up	**
GO_O_GLYCAN_PROCESSING	0.0000092	0.0005718	0.5933255	0.5752207	2.097825	49	MUC5B MUC13 C1GALT1 GALNT14 GALNT6 MUC4 GCNT3 MUC16 CHST4 MUC5AC GALNT4 GALNT10 MUC20 MUC6 GALNT9 XXYLT1 B3GNT3	up	***
GO_CELL_CYCLE_CHECKPOINT	0.0000000	0.0000001	0.8140358	0.4586414	2.097768	198	HMGA2 TRIP13 CDC45 TICRR CHEK2 BUB1B CCNB1 CENPF TIMELESS NDC80 BRCA1 TTK BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB CDC6 TFDP2 ORC1 DTL ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 TP53BP1 KNTC1 RHNO1 BUB1 TOP2A AURKA EME1 ATR TPR MAD1L1 CLSPN PRKDC NSUN2 HORMAD1 CDC25C SOX4 EME2 TOPBP1 CHEK1 NEK11 MAD2L1 SOX11 MDM2 BRIP1 BLM PML CNOT3 CDK1 RFWD3 E2F1 DNA2 CNOT11 MAD2L2 KLHL22 CEP63 INTS7 CNOT2 RAD9A FBXO4 FZR1 PROX1 CDC20 BCL2L1 CHMP4C CDK5RAP2 THOC5 PRMT1 UIMC1	up	***
GO_REGULATION_OF_MACROPHAGE_ACTIVATION	0.0000425	0.0020111	0.5573322	-0.5152345	-2.097529	45	PLA2G10 IL1RL1 GRN SLC7A2 IL10 THBS1 CEBPA CCL3 PTPRC TLR4 IL6 CST7 CD74 SYT11 HAVCR2 CTSC RORA LDLR SPHK1 TREM2 WNT5A SHPK PJA2 MFHAS1	down	**
GO_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0000985	0.0038105	0.5384341	-0.5204298	-2.095397	40	HMOX1 GATA2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 AKT3 FOXC2 KLF4 THBS1 PIK3C2A NOTCH1 RHOJ	down	**
GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	0.0000000	0.0000065	0.7195128	-0.4036103	-2.089592	144	ANGPT4 ACVRL1 SASH1 HMOX1 TEK PPARG GATA2 EMP2 BMPER BMPR2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 PTPRM ADAM17 HSPB1 FOXP1 GATA3 RGCC NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NUS1 ANXA3 PRCP NOTCH1 ETS1 RHOJ	down	***
GO_AXONEMAL_DYNEIN_COMPLEX_ASSEMBLY	0.0000279	0.0014417	0.5756103	0.6689117	2.087218	23	DNAI1 ARMC4 TEKT2 CCDC114 DNAH8 DNAAF3 CCDC40 DRC1 LRRC6 DNAH5 DNAH7 CCDC151 SPAG1 DNAI2 DNAH1 ZMYND10 DNAAF1 WDR63 CCDC65 DNAL1	up	**
GO_CONDENSED_CHROMOSOME	0.0000000	0.0000005	0.7749390	0.4614673	2.087055	174	DDX11 HJURP STAG3L2 BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 BRCA1 L3MBTL1 PLK1 NUF2 AURKB CENPA DYNC1I1 NCAPD2 ZWINT CDT1 SPDL1 TOP3B RSPH1 STAG3 MKI67 BOD1 TP53BP1 KNTC1 BUB1 TOP2A AURKA CBX3 REC8 SYCP2 KIF2C MAD1L1 CENPW CDCA5 FANCD2 HORMAD1 TOPBP1 CHEK1 MAD2L1 CENPO SPC24 BLM PES1 INCENP KNSTRN NCAPG2 CENPH BIRC5 NCAPG SPAG5 RANGAP1 TUBG1 RAD9A LRWD1 NUP85 RAD50 CENPK STAG3L4 CENPV CKAP5 CENPM NOL6 CENPT ADD3 RCC1 ESRRB MSH4 BANF1 RAD51 ZWILCH CHMP1A SMC2 CENPE NCAPD3 RAD1 RRS1 CLASP1 SS18L1 NCAPH	up	***
GO_MITOTIC_CELL_CYCLE_CHECKPOINT	0.0000000	0.0000015	0.7477397	0.4697021	2.084332	152	HMGA2 TRIP13 TICRR CHEK2 BUB1B CCNB1 CENPF NDC80 BRCA1 TTK BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB CDC6 TFDP2 ORC1 ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 KNTC1 BUB1 TOP2A AURKA EME1 TPR MAD1L1 CLSPN PRKDC CDC25C SOX4 EME2 TOPBP1 NEK11 MAD2L1 MDM2 BLM PML CNOT3 CDK1 RFWD3 E2F1 CNOT11 MAD2L2 KLHL22	up	***
GO_CHOLESTEROL_STORAGE	0.0001579	0.0054599	0.5188481	-0.6829403	-2.082591	17	PPARG LPL CD36 MIR146A STARD4 ABCG1 MSR1 EHD1 SOAT1 SREBF2	down	**
GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR	0.0000082	0.0005240	0.5933255	0.5528531	2.079066	57	HMGA2 DDX11 FOXM1 PARPBP TIMELESS POLQ WDR70 FIGNL1 MAGEF1 TP53BP1 AUNIP PRKDC HELB CHEK1 RAD51AP1 PML RECQL5 PARP1 MAD2L2 MGMT NUDT16 PARP9 UBQLN4 TWIST1 DTX3L RTEL1 RAD51 NUDT16L1 SIRT6	up	***
GO_CONDENSED_CHROMOSOME_CENTROMERIC_REGION	0.0000005	0.0000497	0.6749629	0.4998935	2.075346	95	HJURP BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 PLK1 NUF2 AURKB CENPA DYNC1I1 NCAPD2 ZWINT CDT1 SPDL1 BOD1 TP53BP1 KNTC1 BUB1 AURKA CBX3 REC8 KIF2C MAD1L1 CENPW MAD2L1 CENPO SPC24 INCENP KNSTRN CENPH BIRC5 NCAPG SPAG5 RANGAP1 LRWD1 NUP85 CENPK CENPV CKAP5 CENPM	up	***
GO_CONDENSED_NUCLEAR_CHROMOSOME_CENTROMERIC_REGION	0.0000619	0.0026701	0.5384341	0.6829063	2.074959	21	BUB1B CCNB1 NDC80 PLK1 NUF2 AURKB CENPA BUB1 AURKA REC8 CENPO	up	**
GO_DNA_REPLICATION_CHECKPOINT	0.0000337	0.0016834	0.5573322	0.7392760	2.071902	16	CDC45 TICRR TIMELESS CDC6 ORC1 CDT1 CLSPN TOPBP1 DNA2 RAD9A	up	**
GO_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING	0.0000226	0.0012312	0.5756103	-0.4831026	-2.069674	56	THBD TBXA2R TGFBR2 SCARF1 CD36 ANXA1 HBEGF CLEC7A NFE2L2 NDEL1 GRN FOXC2 THBS1 SELP HPSE TLR4 PLEK KANK1 CNTF DUOX1 ENPP4 PRKCE	down	**
GO_CELL_FATE_DETERMINATION	0.0001870	0.0063165	0.5188481	-0.5624553	-2.069203	29	GATA2 SOX17 CDC42 DSCAML1 TBX2 GATA3 MCL1 KLF4 CYP26B1 HES1 EBF2 IFRD1 GATA6 PTCH1	down	**
GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS	0.0002518	0.0080074	0.4984931	-0.6940495	-2.069142	15	SPN TNFRSF8 CLEC7A HSPB1 THBS1 TLR4 PSEN1 TYROBP	down	**
GO_CARDIAC_MUSCLE_CELL_PROLIFERATION	0.0000699	0.0029320	0.5384341	-0.5000088	-2.063890	46	RBP4 PRKAR1A TGFBR3 TGFBR2 TBX2 FOXC2 TBX5 MIR17HG TGFB2 RBPJ NOTCH1 SAV1 PIM1 MEIS1 GATA6 RXRA FGF2 PTEN FGFR1 MIR548C ZFPM2 MAPK1 NOG JARID2 BMPR1A YAP1 ERBB4	down	**
GO_CHROMOSOME_CENTROMERIC_REGION	0.0000000	0.0000041	0.7337620	0.4606081	2.061989	160	PKHD1 HELLS HJURP BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TTK PLK1 NUF2 CDCA8 AURKB CENPA DYNC1I1 MIS18A NCAPD2 ZWINT CDT1 DCTN2 SPDL1 STAG3 BOD1 TP53BP1 KNTC1 BUB1 CENPL AURKA CBX3 REC8 TPR KIF2C MAD1L1 CENPW CDCA5 MAD2L1 CENPO SPC24 DSCC1 INCENP KNSTRN CBX5 CENPH BIRC5 NCAPG SPAG5 TRAPPC12 MTBP CBX1 CENPP RANGAP1 DNMT1 KIF22 HIRA CENPQ ESCO2 LRWD1 NUP85 CENPK CENPV CKAP5 CENPM DNMT3A DYNC1LI2 CENPT	up	***
GO_DNA_INTEGRITY_CHECKPOINT	0.0000001	0.0000087	0.7049757	0.4679436	2.059796	141	HMGA2 CDC45 TICRR CHEK2 CCNB1 TIMELESS BRCA1 BRSK1 E2F8 GTSE1 PLK1 CDC6 TFDP2 ORC1 DTL CDT1 CDK5RAP3 CASP2 TP53BP1 RHNO1 TOP2A AURKA EME1 ATR CLSPN PRKDC CDC25C SOX4 EME2 TOPBP1 CHEK1 NEK11 MDM2 BRIP1 BLM PML CNOT3 CDK1 RFWD3 E2F1 DNA2 CNOT11 CEP63 INTS7 CNOT2 RAD9A FBXO4 FZR1	up	***
GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY	0.0002871	0.0088437	0.4984931	-0.6909092	-2.059780	15	ACVRL1 SOSTDC1 BMPR2 TGFBR3 TGFBR2 LTBP4	down	**
GO_MITOTIC_SPINDLE_ORGANIZATION	0.0000011	0.0001035	0.6435518	0.4989754	2.056715	93	SPICE1 CHEK2 NEK2 CCNB1 NDC80 TTK RACGAP1 STIL MSTO1 PLK1 NUF2 AURKB TPX2 MYBL2 PRC1 DCTN2 WDR62 KIF23 KIF3B MAP10 AURKA TPR POC1A FSD1 KIF11 GPSM2 PSRC1 CEP97 BIRC5 KIF2A KPNB1 CEP192 TUBG1 TACC3 CDC20 TUBG2 AAAS EFHC1 CHMP4C RCC1 NUP62 CHMP1A CHMP2A CENPE GOLGA2 MAP9 CLASP1 DRG1 DYNC1H1 WRAP73 PCNT	up	***
GO_HEART_TRABECULA_MORPHOGENESIS	0.0001520	0.0053058	0.5188481	-0.5709089	-2.056462	28	RBP4 TEK CCM2L ENG S1PR1 TGFBR3 HEG1 TGFB2 SRF RBPJ NOTCH1	down	**
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION	0.0001391	0.0049978	0.5188481	-0.5539790	-2.052465	30	IL1A IL1B ANXA1 CLEC7A TRAF6 SPTBN1 PDE4D PTPRC CD80 CD83 MALT1 CD86 PDE4B RIPK2	down	**
GO_POSITIVE_REGULATION_OF_WOUND_HEALING	0.0000843	0.0033518	0.5384341	-0.4970731	-2.051772	46	THBD TBXA2R TGFBR2 CD36 ANXA1 HBEGF CLEC7A NFE2L2 FOXC2 THBS1 SELP HPSE TLR4 PLEK KANK1 DUOX1 ENPP4 PRKCE	down	**
GO_DNA_GEOMETRIC_CHANGE	0.0000006	0.0000600	0.6594444	0.4889582	2.046881	99	DDX11 DDX12P RUVBL1 CDC45 POLQ PIF1 GINS1 MCM4 MCM2 RAD54B MCM8 GINS4 RUVBL2 TOP2A SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 MNAT1 RECQL5 PARP1 SSBP1 NAV2 DNA2 RECQL4 CHTF18 GINS2 CHD5 RAD50 HMGA1 RPA1 MCM6 CHTF8 MCM5 ZRANB3 IGHMBP2 RTEL1 RFC5 RAD51 CHD3 XPC TP53	up	***
GO_CHROMOSOME_SEGREGATION	0.0000000	0.0000000	0.8390889	0.4355194	2.045846	259	TRIP13 DDX11 SPICE1 DDX12P HJURP STAG3L2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 BRCA1 TTK CDCA2 RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ECT2 ESPL1 CDC6 PRC1 MIS18A SRPK1 NCAPD2 ZWINT CDT1 SPDL1 TOP3B KIF23 STAG3 MKI67 BOD1 BUB1 TOP2A MAP10 EME1 REC8 SYCP2 TPR KIF2C MAD1L1 CENPW CDCA5 FANCD2 HORMAD1 EME2 NEK11 MAD2L1 DSCC1 BRIP1 RAD18 ERCC2 RECQL5 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 BIRC5 SUN1 DIS3L2 NCAPG FEN1 SPAG5 TRAPPC12 MAD2L2 KLHL22 KPNB1 CCNE1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA CENPQ AKAP8L ESCO2 ANAPC1 SLX4 ANKRD31 CENPK STAG3L4 MEI1 CDC20 TUBG2 CHMP4C FANCM CDK5RAP2 CHTF8 CENPT	up	***
GO_MITOCHONDRIAL_TRANSLATION	0.0000002	0.0000250	0.6901325	0.4723740	2.045659	124	TSFM MRPL46 SHMT2 MRPS35 UQCC1 AARS2 MRPL15 LARS2 ERAL1 MRPL3 MRPL27 TARS2 SARS2 MRPS11 MRPS30 MTG1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 UQCC2 COA3 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 YARS2 IARS2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 CDK5RAP1 GADD45GIP1 MTIF3 MRPL9 MRPL21 AURKAIP1 EARS2 MRPS27 MRPL20 MRPL48 MRPS26 TRUB2 MTG2 RPUSD3 MRPS16 MRPL12 MRPL43 FASTKD3 MRPL2	up	***
GO_MICROTUBULE_BUNDLE_FORMATION	0.0000029	0.0002257	0.6272567	0.5218200	2.042347	70	KIF20A SPAG17 TTC26 PLK1 PRC1 DNAI1 RSPH1 ARMC4 SPAG16 HYDIN TEKT2 CCDC114 DNAH8 GAS8 DNAAF3 CCDC40 PSRC1 DRC1 LRGUK LRRC6 DNAH5 DNAH7 CCDC151 IQCG SPAG1 DNAJB13 AAAS TTLL3 CDK5RAP2 DNAI2 TTLL6 RSPH4A NAV1 DNAH1 MARK4 ZMYND10 CLASP1 ARMC2 DNAAF1 WDR63	up	***
GO_SPROUTING_ANGIOGENESIS	0.0000018	0.0001507	0.6435518	-0.4172578	-2.039271	111	SEMA6A ACVRL1 HMOX1 TEK ADTRP GATA2 BMPER RAMP2 CDH13 TBXA2R CDC42 MIR27B RHOA ANXA1 MIR146A MMRN2 ITGA5 CLEC14A NR4A1 AKT3 FOXC2 IL10 NRARP KLF4 THBS1 ADAMTS9 MIR24-2 RECK PIK3C2A SRF FLT1 NOTCH1 JAK1 RHOJ KLF2 JMJD6 MIR23A MIA3 FGF2 EPN2 EPHA2 PARVA GLUL FLT4 STARD13 GREM1 ITGB1 MIR2355 EFNB2	down	***
GO_CONDENSED_NUCLEAR_CHROMOSOME	0.0000035	0.0002640	0.6272567	0.5203906	2.036752	70	BUB1B NEK2 CCNB1 NDC80 BRCA1 PLK1 NUF2 AURKB CENPA NCAPD2 RSPH1 STAG3 BUB1 AURKA REC8 SYCP2 HORMAD1 TOPBP1 CHEK1 CENPO BLM INCENP TUBG1 RAD9A RAD50 CENPK NOL6 ADD3 RCC1 MSH4 RAD51 CHMP1A NCAPD3 RAD1 RRS1 SS18L1 NCAPH MLH3 DSN1 KIFAP3	up	***
GO_VENTRICULAR_TRABECULA_MYOCARDIUM_MORPHOGENESIS	0.0007179	0.0177101	0.4772708	-0.6909372	-2.036270	14	CCM2L ENG HEG1 TGFB2 RBPJ NOTCH1	down	*
GO_CHROMOSOMAL_REGION	0.0000000	0.0000000	0.8513391	0.4300730	2.033767	278	PKHD1 HELLS HJURP CHEK2 BUB1B NUP107 NEK2 CCNB1 CENPF THOC3 NDC80 PIF1 TTK NABP2 PLK1 NUF2 CDCA8 AURKB CENPA MCM4 MCM2 ORC1 DYNC1I1 MIS18A NCAPD2 ZWINT CDT1 DCTN2 SPDL1 STAG3 BOD1 TP53BP1 KNTC1 BUB1 CENPL AURKA CBX3 REC8 ATR TPR KIF2C MCM7 MAD1L1 CENPW CDCA5 PRKDC MCM3 CHEK1 MAD2L1 CENPO XRCC1 SPC24 DSCC1 BLM PML PARP1 INCENP KNSTRN TERC CBX5 CDK1 CENPH BIRC5 NCAPG DNA2 FEN1 EZH2 SPAG5 TRAPPC12 MTBP CBX1 RECQL4 CENPP TEP1 RANGAP1 DNMT1 TELO2 DCLRE1C KIF22 HIRA RAD51D CENPQ ESCO2 LRWD1 POLD1 NUP85 SLX4 RAD50 CENPK CENPV CKAP5 CENPM RPA1 MCM6 DNMT3A THOC5 WRNIP1 DYNC1LI2 CENPT MCM5	up	***
GO_CONDENSED_NUCLEAR_CHROMOSOME_KINETOCHORE	0.0000730	0.0030459	0.5384341	0.7410734	2.033167	15	BUB1B CCNB1 NDC80 PLK1 NUF2 CENPA BUB1 REC8 CENPO	up	**
GO_CHROMATIN_REMODELING_AT_CENTROMERE	0.0001030	0.0039549	0.5384341	0.6350120	2.032253	26	HELLS HJURP RUVBL1 CENPA MIS18A CENPL CENPW CENPO CENPH CENPP CENPQ CENPK CENPV CENPM CENPT	up	**
GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION	0.0000284	0.0014527	0.5756103	0.5777500	2.031049	40	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 MAD2L2 KLHL22	up	**
GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME	0.0000079	0.0005144	0.5933255	0.5248453	2.029247	66	NDC80 TTK NABP2 PLK1 AURKB CENPA CCT6A MCM8 CDT1 CCT2 SPDL1 RUVBL2 BOD1 CCT5 ATR CDCA5 PIH1D1 CDK1 CCT3 EZH2 TRAPPC12 MTBP CENPQ ESCO2 LRWD1 ESR1 CCT7 PPHLN1 RPA1	up	***
GO_BASE_EXCISION_REPAIR	0.0000437	0.0020489	0.5573322	0.5745847	2.028740	41	HMGA2 POLQ POLE LIG3 SMUG1 POLM LIG1 XRCC1 PRMT6 UNG DNA2 NEIL3 FEN1 POLL MBD4 POLD1 POLB HMGA1 RPA1 SIRT6 MPG TP53 NEIL1 APEX1 PARP2	up	**
GO_CHROMATIN_ASSEMBLY	0.0000061	0.0004174	0.6105269	0.5144403	2.026646	72	HMGA2 HELLS HJURP RUVBL1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A CHAF1A CENPL TPR CENPW CHAF1B CENPO ASF1B CENPH CENPP HIRA CENPQ NOC2L CENPK CENPV CENPM HMGA1 CENPT	up	***
GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.0000440	0.0020568	0.5573322	-0.4754947	-2.025327	55	ANGPT4 HMOX1 GATA2 MIR27B ANXA1 MIR146A ADAM17 HSPB1 NFE2L2 AKT3 FOXC2 MAP2K3 STAT5A AMOTL1 THBS1 PIK3C2A NUS1 ETS1 RHOJ TGFB1 MIR23A	down	**
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_BIOSYNTHETIC_PROCESS	0.0009554	0.0214690	0.4772708	-0.7043571	-2.023559	13	EREG IL1B CLEC7A TRAF6 PTAFR TYROBP CD74	down	*
GO_SEQUESTERING_OF_TRIGLYCERIDE	0.0008522	0.0197861	0.4772708	-0.7391838	-2.022562	11	ABHD5 OSBPL11 PPARG IL1B LPL	down	*
GO_OLIGOSACCHARIDE_CATABOLIC_PROCESS	0.0007603	0.0183002	0.4772708	-0.7872938	-2.021880	9	MANBA MAN2B1 GM2A TREH CTBS HEXB	down	*
GO_CILIUM_ORGANIZATION	0.0000000	0.0000000	0.8390889	0.4218672	2.021152	304	CCNO PKHD1 MCIDAS ONECUT2 ONECUT1 CEP72 CEP89 RPGRIP1L NEK2 AVIL NUDCD3 RAB3IP MKS1 CCDC113 STK36 IFT122 SPAG17 TTC26 CEP70 PLK1 IFT27 KIF27 DCTN2 WDR90 DNAI1 HAUS5 CEP250 RSPH1 ARMC4 BBS1 SPAG16 FOXJ1 KIF3B CCDC13 FBF1 ODF2 SFI1 IFT43 POC1A HYDIN TEKT2 CCDC114 DCDC2 WDR60 NME5 DNAH8 IFT172 GAS8 KIF3C CBY1 DNAAF3 RABEP2 C2CD3 CCDC40 DRC1 LRGUK LRRC6 IQCB1 CDK1 CROCC CEP97 CENPJ VANGL2 KIF19 TCTN2 SSX2IP DYNLL2 POC1B LCA5 DNAH5 TMEM231 FGFR1OP IFT52 CEP63 BBS5 CEP192 NPHP1 TUBG1 DNAH7 NINL MNS1 CCDC151 IQCG TMEM237 SPAG1 TEKT3 TRAF3IP1 DNAJB13 CKAP5 IQUB ROPN1B WDR34 TTLL3 TCTN1 CDK5RAP2 ODF2L DNAI2 WDR35 HAUS6 DYNC2H1 FAM161A TBC1D30 HAUS4 RSPH4A TCHP UNC119B CEP152 TMEM17 B9D1 ALMS1 ICK CEP164 CLUAP1 DNAH1 MARK4 CELSR2 TBC1D32 TTC39C VDAC3 UBXN10 CELSR3 SYNE2 TTC30B ZMYND10 CLASP1 KIF24 KIAA0586 CEP290 ARMC2 DNAAF1 DYNC1H1 MAK TEKT1 ABLIM3 WRAP73 WDR63 PLK4 AKAP9 PCNT	up	***
GO_CILIUM_MOVEMENT	0.0000110	0.0006774	0.5933255	0.5499615	2.020859	52	STK36 SPAG17 DNAH3 KIF27 DNAI1 ARMC4 HYDIN WDR78 DPCD TEKT2 CCDC114 WDR66 NME5 GAS8 DNAH11 CCDC40 DRC1 KIAA0556 LRRC6 DNAH5 DNAH7 CCDC151 TEKT3 SPA17 DNAI2 TTLL6 RSPH4A CATSPER1 DNAH1 CELSR2 DNAAF1 TEKT1 WDR63 ROPN1L CCDC65 DNAH9 CABYR	up	***
GO_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	0.0005833	0.0151676	0.4772708	-0.5962622	-2.020134	22	ACVRL1 ACE DLC1 IL1B CORO1C APOD ROCK2 ROCK1 THBS1 FAM107A	down	*
GO_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING	0.0003760	0.0107943	0.4984931	-0.6193039	-2.019555	20	ACVRL1 ENG TGFBR3 TGFBR2 CD36 LTBP4 CD93 THBS1 NRROS LRRC32 LTBP1 LTBP3 CD109	down	*
GO_ENDOTHELIAL_CELL_MIGRATION	0.0000000	0.0000010	0.7614608	-0.3841501	-2.018261	184	ANGPT4 ACVRL1 SASH1 HMOX1 SOX18 TEK PECAM1 PPARG ADTRP GATA2 EMP2 BMPER CDH13 BMPR2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 PTPRM ADAM17 CLEC14A HSPB1 FOXP1 GATA3 NR4A1 RGCC NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 TNFSF12 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NUS1 ANXA3 SRF PRCP	down	***
GO_DNA_REPLICATION_INDEPENDENT_NUCLEOSOME_ORGANIZATION	0.0000330	0.0016551	0.5573322	0.6022695	2.016326	32	HJURP RUVBL1 CABIN1 CENPA MIS18A CENPL CENPW CENPO ASF1B CENPH CENPP HIRA CENPQ CENPK SUPT16H CENPM CENPT	up	**
GO_COPULATION	0.0006976	0.0172841	0.4772708	-0.7165487	-2.016152	12	SLC6A4 EDNRB P2RY1 DDO ADA	down	*
GO_RECOMBINATIONAL_REPAIR	0.0000009	0.0000894	0.6594444	0.4721178	2.013148	113	CDC45 PARPBP TIMELESS POLQ BRCA1 NABP2 FIGNL1 RBBP8 MCM4 MCM2 RAD54B XRCC2 MCM8 LIG3 GINS4 MAGEF1 TP53BP1 RHNO1 AUNIP REC8 MCM7 MMS22L HELB RAD54L MCM3 CHEK1 RAD51AP1 XRCC1 BLM RECQL5 PARP1 POLN RFWD3 AP5Z1 FEN1 MAD2L2 RECQL4 POLL RAD51D GINS2 SLX4 CDC7 RAD50 UBQLN4 PALB2 RPA1 MCM6 MCM5	up	***
GO_CILIARY_PLASM	0.0000029	0.0002257	0.6272567	0.4893220	2.010684	92	DNAH2 RPGRIP1L CENPF SPAG17 DNAH3 AK8 DNAI1 ARMC4 BBS1 SPAG16 HYDIN WDR78 CCDC114 DCDC2 WDR66 DNAH8 IFT172 GAS8 DNAH11 TULP3 CCDC40 DRC1 KIF19 SPAG6 LCA5 DNAH5 SPEF1 BBS5 DNAH7 MNS1 CCDC151 TRAF3IP1 DNAJB13 WDR34 TTLL3 EFHC1 RPGRIP1 DNAI2 WDR35 DYNC2H1 NEK4 RSPH4A	up	***
GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_5_PHOSPHATASE_ACTIVITY	0.0010239	0.0226551	0.4550599	-0.7339841	-2.008335	11	FIG4 INPP5K PTPMT1 INPP5B PIKFYVE	down	*
GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY	0.0002277	0.0075406	0.5188481	-0.5415857	-2.006549	30	ACVRL1 CITED2 BMPR2 FGF10 TGFBR2 NODAL SMAD7 INHBA MAGI2 FSTL3 SMAD2 FKBP1A DACT2 SKI ACVR1C	down	**
GO_POSITIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS	0.0011804	0.0245626	0.4550599	-0.6449348	-2.005184	18	IL1B LHCGR WNT4 P2RY1 ADCYAP1R1 ABCG1 PTAFR PTH1R HRH1	down	*
GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT	0.0000073	0.0004813	0.6105269	0.4812235	2.004240	96	HMGA2 TICRR CHEK2 CCNB1 BRSK1 E2F8 GTSE1 CDC6 TFDP2 ORC1 CDK5RAP3 CASP2 TOP2A AURKA EME1 CLSPN PRKDC CDC25C SOX4 EME2 TOPBP1 NEK11 MDM2 BLM PML CNOT3 CDK1 RFWD3 E2F1 CNOT11 CNOT2 RAD9A	up	***
GO_CELL_CYCLE_DNA_REPLICATION	0.0000186	0.0010628	0.5756103	0.5310636	2.000702	58	CDC45 CHEK2 PRIM2 GINS1 E2F8 DBF4B POLE MCM4 MCM2 CDT1 POLA2 POLD2 MCM7 MCM3 LIG1 POLE2 GMNN DNA2 FEN1 POLD1 ATAD5 CDC7 RPA1 MCM6 MCM5 PRIM1 RTEL1 RFC5 NUGGC RAD51 BCL6 E2F7 WIZ	up	**
GO_3_5_CYCLIC_AMP_PHOSPHODIESTERASE_ACTIVITY	0.0008553	0.0197861	0.4772708	-0.7106799	-1.999639	12	PDE1B PDE4C PDE2A PDE4D PDE8A PDE3B PDE4B PDE4A PDE8B PDE7B	down	*
GO_KINETOCHORE	0.0000012	0.0001072	0.6435518	0.4683509	1.997436	114	HJURP BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TTK PLK1 NUF2 AURKB CENPA DYNC1I1 ZWINT CDT1 DCTN2 SPDL1 BOD1 TP53BP1 KNTC1 BUB1 REC8 TPR KIF2C MAD1L1 CENPW MAD2L1 CENPO SPC24 INCENP KNSTRN CBX5 CENPH BIRC5 SPAG5 TRAPPC12 MTBP RANGAP1 KIF22 CENPQ LRWD1 NUP85 CENPK CENPV CKAP5 CENPM DYNC1LI2 CENPT	up	***
GO_MITOTIC_NUCLEAR_DIVISION	0.0000000	0.0000007	0.7749390	0.4275128	1.996200	237	TRIP13 SPICE1 CHEK2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK SMPD3 RACGAP1 KIF14 L3MBTL1 ANLN MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 TPX2 MYBL2 PRC1 NCAPD2 ZWINT CDT1 SPDL1 RANBP1 KIF23 MKI67 CUL9 BOD1 CUL7 KNTC1 KIF3B BUB1 MAP10 AURKA TPR KIF2C MAD1L1 CDCA5 TOM1L1 KIF11 CDC25C CHEK1 MAD2L1 DSCC1 PKMYT1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 CEP97 BIRC5 DIS3L2 NCAPG KIF2A SPAG5 EGF MTBP MAD2L2 KLHL22 KPNB1 CEP192 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA AKAP8L KIF20B ANAPC1 CDK13 CENPK SH2B1 CDC20 TUBG2 AAAS CHMP4C CDK5RAP2 CHTF8 KATNB1 RCC1 PRMT5 NUP62 CEP85 CHMP1A CHMP2A AURKAIP1 SMC2 MAU2 CENPE GOLGA2 UBE2C NCAPD3 MAP9 RRS1 CLASP1 NCAPH POGZ CHMP6 PDXP DRG1 WRAP73 DSN1 FBXO5 LCMT1 NFE2L1 NSL1 MAD2L1BP	up	***
GO_MICROTUBULE_ASSOCIATED_COMPLEX	0.0000005	0.0000509	0.6594444	0.4563884	1.995552	135	KIF1A KIF12 KLC3 KIF20A DNAH2 KIF18B NUDCD3 KIF14 CDCA8 AURKB DNAH3 DYNC1I1 KIF27 DNAH14 DCTN2 DNAI1 HAUS5 MAP7 KIF23 KIF15 KIF3B AURKA TPR KIF2C WDR78 CCDC114 KIF11 WDR60 DNAH8 KIF3C DNAH11 FNTB TTBK1 DRC1 DNAH6 KIF5A SNX4 BIRC5 KIF19 KIF2A KIF7 DYNLL2 DNAH5 DNAH7 KIF22 KIF21A KIF20B KLC2 KLC4 WDR34 DYNC1LI2 KIF21B DNAI2 HAUS6 DYNC2H1 KATNB1 HAUS4	up	***
GO_NEGATIVE_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_JAK_STAT	0.0004505	0.0125774	0.4984931	-0.6118877	-1.995370	20	DAB1 CAV1 MIR146A SH2B3 ADIPOR1 SOCS2 PPP2CA SOCS3	down	*
GO_KINESIN_COMPLEX	0.0000636	0.0027315	0.5384341	0.5471254	1.995362	49	KIF1A KIF12 KLC3 KIF20A KIF18B KIF14 KIF27 KIF23 KIF15 KIF3B KIF2C KIF11 KIF3C KIF5A KIF19 KIF2A KIF7 KIF22 KIF21A KIF20B KLC2 KLC4 KIF21B	up	**
GO_BLOOD_VESSEL_MORPHOGENESIS	0.0000000	0.0000000	1.0073180	-0.3352631	-1.992253	505	ANGPT4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB CDH5 ENG FOLR1 ECSCR SOX17 CAV1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 HSPG2 HEG1 RHOA APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM RAP1A ITGA5 CLEC14A HSPB1 FZD4 ANPEP NR4A1 JAM3 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 SPI1 PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 ROCK2 AMOTL1 NRARP TBX4 TNFSF12 TSPAN12 KLF4 ROCK1 THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HPSE MIR24-2 RECK PIK3C2A ELK3 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS HES1 PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ FLT1 IL6 WASF2 PKNOX1 CD160 NDNF JUN NOTCH1 ETS1 JUNB JAK1 RHOJ	down	***
GO_POSITIVE_REGULATION_OF_SPROUTING_ANGIOGENESIS	0.0005141	0.0140421	0.4772708	-0.4944081	-1.989980	39	HMOX1 GATA2 BMPER MIR27B ANXA1 MIR146A ITGA5 AKT3 FOXC2 IL10 KLF4 PIK3C2A JAK1 RHOJ	down	*
GO_ATPASE_ACTIVITY	0.0000000	0.0000000	0.8870750	0.4096399	1.988930	366	KIF1A KIF12 ABCA13 DDX11 ABCC2 HELLS KIF20A DDX12P RUVBL1 CDC45 DNAH2 POLQ KIF18B TTF2 PIF1 GINS1 KIF14 ABCA12 PMS2P5 FIGNL1 MCM4 MCM2 RAD54B DNAH3 PMS2 XRCC2 DYNC1I1 MCM8 GINS4 KIF27 DNAH14 DNAI1 RUVBL2 TNNT2 KIF23 HLTF KIF15 KIF3B TOP2A MYO10 SMARCAL1 KIF2C MCM7 WDR78 ABCC5 RHOBTB3 HELB RAD54L KIF11 MCM3 PEX6 PFN2 WDR60 CHD6 DNAH8 MORC2 ABCB6 KIF3C ABCB9 DSCC1 DNAH11 BRIP1 BLM ERCC2 MNAT1 RECQL5 DDX56 NSF DDX51 DNAH6 KIF5A NAV2 DHX37 ABCC11 KIF19 DNA2 KIF2A DHX33 KIF7 DYNLL2 DNAH5 ABCA4 PSMC4 RECQL4 DHX34 MYO19 MOV10 DNAH7 DHX40 LONP1 KIF22 RAD51D CHTF18 KIF21A GINS2 KIF20B CHD5 ATAD5 ATP13A1 RAD50 ABCC10 EP400 ABCC9 WDR34 ABCC3 ABCA7 FANCM MCM6 CHTF8 WRNIP1 KIF21B DHX8 MCM5 DNAI2 ZRANB3 DDX23 DYNC2H1 KATNB1 IGHMBP2 MYH3 ABCD4 DDX55 ATAD2 PMS2P1 MSH4 PMS1 MSH2 SMARCA4 DDX54 ABCF3 RTEL1 RFC5 ABCF2 DNAH1 RAD51 SNRNP200 CHD3 RNF213 CENPE SRCAP DDX52 HSPA7	up	***
GO_REGULATION_OF_CHROMOSOME_SEGREGATION	0.0000030	0.0002340	0.6272567	0.4841685	1.988615	90	TRIP13 DDX11 BUB1B NEK2 CCNB1 CENPF NDC80 TTK RACGAP1 PLK1 AURKB PTTG1 ECT2 ESPL1 CDC6 CDT1 SPDL1 MKI67 BUB1 TPR KIF2C MAD1L1 CDCA5 HORMAD1 MAD2L1 RAD18 KNSTRN ANAPC5 FEN1 SPAG5 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3	up	***
GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT	0.0000087	0.0005476	0.5933255	-0.4094422	-1.988001	102	ANGPT4 SEMA6A TEK PPARG HHEX TIE1 WNT4 ECSCR GTF2I TBXA2R NFATC3 HSPG2 RHOA MIR146A MMRN2 PTPRM RGCC SPRY2 GPR4 ROCK2 KLF4 ROCK1 THBS1 ADAMTS9 CLDN5 PDE3B MIR24-2 TGFB2 CD160 NOTCH1 NPR1 KLF2 ISM1 VASH1 EPN2 SEMA4A EPHA2 FOXJ2 STARD13 SERPINE1 ATF2 CX3CR1 MIR640 MIR2355	down	***
GO_DNA_REPLICATION	0.0000000	0.0000009	0.7614608	0.4253872	1.987892	240	MCIDAS DDX11 CDC45 TICRR MCM10 CHEK2 TIMELESS POLQ PRIM2 PIF1 BRCA1 GINS1 E2F8 DBF4B POLE CDC6 RBBP8 MCM4 MCM2 ORC1 DTL MCM8 LIG3 GINS4 CDT1 EXO1 CHAF1A RHNO1 EME1 POLA2 ATR POLD2 SMARCAL1 MCM7 CLSPN RRM2 MMS22L WDHD1 HELB MCM3 CHAF1B EGFR LIG1 EME2 TOPBP1 CHEK1 ORC6 DSCC1 BRIP1 REPIN1 BLM RECQL5 POLN ING4 CDK1 SSBP1 POLE2 DTD1 RFWD3 GMNN KCTD13 DNA2 FEN1 RECQL4 RNASEH2A CCNE1 DNAJA3 POLL RAD9A SSRP1 CHTF18 ESCO2 GINS2 LRWD1 POLD1 POLB ATAD5 SLX4 NT5M CDC7 RAD50 SUPT16H STOML2 FAF1 HMGA1 RPA1 FANCM MCM6 MGME1 CHTF8 WRNIP1 MCM5 ZRANB3 GINS3 IGHMBP2 CCNA2 PRIM1 RTEL1 RFC5 NUGGC RAD51 PNKP TONSL BCL6 E4F1 TP53	up	***
GO_MITOCHONDRIAL_GENE_EXPRESSION	0.0000002	0.0000270	0.6749629	0.4478837	1.986419	146	TSFM TBRG4 MRPL46 SHMT2 MRPS35 UQCC1 AARS2 MRPL15 LARS2 ERAL1 MRPL3 MRPL27 TARS2 SARS2 TRMT61B MRPS11 MRPS30 MTG1 TRIT1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 UQCC2 COA3 PUS1 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 ELAC2 YARS2 IARS2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 CDK5RAP1 GADD45GIP1 MTIF3 MRPL9 MRPL21 AURKAIP1 EARS2 MRPS27 MRPL20 MRPL48 MRPS26 TRUB2 MTG2 RPUSD3 POLRMT MRPS16 PPARGC1B MRPL12 MRPL43 FASTKD3 MRPL2 TEFM MRPS6	up	***
GO_SINGLE_STRANDED_DNA_HELICASE_ACTIVITY	0.0001774	0.0060370	0.5188481	0.7057903	1.978054	16	POLQ PIF1 MCM2 MCM7 HELB DSCC1 DNA2 CHTF18 MCM6 CHTF8 MCM5 RFC5 RAD51	up	**
GO_MOTOR_ACTIVITY	0.0000014	0.0001288	0.6435518	0.4585436	1.975357	120	KIF1A KIF12 KLC3 KIF20A DNAH2 MYO3B KIF18B MYH16 KIF14 DNAH3 DYNC1I1 KIF27 MYL6B DNAH14 DCTN2 DNAI1 KIF23 KIF15 KIF3B MYO10 KIF2C WDR78 KIF11 WDR60 DNAH8 KIF3C DNAH11 MYO1A DNAH6 KIF5A KIF19 KIF2A KIF7 DYNLL2 MYO5B DNAH5 MYO19 DNAH7 KIF22 KIF21A KIF20B KLC2 KLC4 WDR34 MYO5C DYNC1LI2 KIF21B DNAI2 DYNC2H1 MYH7B MYH3 MYH13	up	***
GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK	0.0009305	0.0211130	0.4772708	-0.5719767	-1.970935	23	SIK1 CRY2 RBM4 PER3 USP2 FBXL3 PER2 ID2 PER1 GNAQ	down	*
GO_TERTIARY_GRANULE_MEMBRANE	0.0002328	0.0076364	0.5188481	-0.4561131	-1.968809	57	OLR1 CLEC12A PTPRB SLC11A1 CD33 STOM LAIR1 SIRPA CD93 LAMTOR3 RAB14 PTAFR GAA ITGAX CD53 FCER1G HGSNAT SNAP23 ATP11A SERPINB6 SIGLEC14 FPR2 TSPAN14 ATP6V0C GPR84 ADAM10	down	**
GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.0000000	0.0000043	0.7337620	-0.3627884	-1.967836	202	ANGPT4 ACVRL1 SASH1 HMOX1 TEK PPARG GLIPR2 GATA2 EMP2 BMPER CORO1C BMPR2 TBXA2R FGF10 MIR27B TGFBR2 RHOA ANXA1 MIR146A MMRN2 PTPRM HBEGF ARSB ADAM17 HSPB1 FOXP1 ADIPOR1 GATA3 RGCC NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NUS1 ANXA3 MAPRE2 TGFB2 PRCP JUN NOTCH1 ETS1 MAP4K4 RHOJ PRKCE PPM1F PLCG2 EPPK1 TGFB1 MIR23A CLASP2 MACF1 CCR6 FGF2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 SP100 EPHA2 GLUL EDN1 PTEN FGFR1 NRP2 FLT4 STARD13 CTSH HAS2 MIR640 MIR2355 CALR WNT5A ANGPT2 HMGB1 ATOH8 DOCK5 SIRT1 PTGS2 SEMA5A CAPN7	down	***
GO_BICARBONATE_TRANSPORT	0.0001072	0.0040689	0.5384341	0.5762952	1.967233	34	CA9 SLC26A4 HBA1 HBA2 SLC26A8 SLC4A3 SLC4A4 CA12 HBB SLC4A8 SLC4A11 SLC26A2 SLC4A2 SLC4A9 SLC26A1	up	**
GO_NEGATIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE	0.0003130	0.0093839	0.4984931	0.5718124	1.966345	36	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 MAD2L2 KLHL22	up	**
GO_MICROVILLUS_MEMBRANE	0.0001854	0.0062852	0.5188481	0.6580810	1.964531	20	CEACAM1 CDHR2 CA9 PROM1 PTPRH MUC20 SLC9A3R1 PROM2 SLC26A2	up	**
GO_B_CELL_PROLIFERATION	0.0000677	0.0028698	0.5384341	-0.4387204	-1.961017	68	GAPT MNDA CD22 CLCF1 ADA MS4A1 IFNK WNT3A TFRC IL10 BST1 CDKN1A PTPRC TLR4 IL7R NCKAP1L TYROBP GPR183 RC3H1 PELI1 CD74 VAV3 IRS2 CD81	down	**
GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION	0.0002221	0.0073806	0.5188481	0.6989697	1.958939	16	GINS1 POLE MCM4 LIG3 GINS4 POLD2 MCM7 MCM3 LIG1 DNA2 GINS2 GINS3	up	**
GO_ANGIOGENESIS_INVOLVED_IN_WOUND_HEALING	0.0011013	0.0235454	0.4550599	-0.5775681	-1.956798	22	FOXC2 GPR4 HPSE ADIPOR2 SRF PRCP NDNF ETS1 MCAM CD34 CXCR4 SERPINE1	down	*
GO_VASCULOGENESIS	0.0000765	0.0031508	0.5384341	-0.4374596	-1.955382	68	TMEM100 FOXF1 SOX18 RASIP1 TIE1 EMP2 RAPGEF2 RAMP2 ENG SOX17 CAV1 QKI TGFBR3 TGFBR2 HEG1 RAP1A FZD4 TIPARP ZMIZ1	down	**
GO_REPLICATION_FORK	0.0000588	0.0025783	0.5573322	0.5126934	1.955155	62	CDC45 MCM10 TIMELESS PRIM2 PIF1 UHRF1 XRCC2 GINS4 TP53BP1 POLA2 POLD2 SMARCAL1 MMS22L WDHD1 HELB MCM3 RAD18 BLM ZMIZ2 DNMT1 RAD51D GINS2 POLD1 RPA1 ZRANB3 HMCES PRIM1 RFC5 TONSL BCL6 TP53	up	**
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION	0.0001240	0.0045364	0.5188481	-0.4420773	-1.949832	65	EREG IL1A SCIMP SIGLEC16 IL1B LPL MYD88 IL1RN CD36 CLEC7A TRAF6 ARHGEF2 PTAFR TLR4 FCER1G IL17D IL6 TYROBP MBP CD74 AKIRIN2	down	**
GO_FATTY_ACID_BINDING	0.0011332	0.0240742	0.4550599	-0.5563937	-1.949787	25	FFAR4 PPARG FABP4 ACOXL APOC1 FABP5 SCP2 ID3 STX3 ALOX5AP	down	*
GO_TYPE_I_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_BINDING	0.0021676	0.0371688	0.4317077	-0.7590317	-1.949299	9	SMAD6 ENG TGFBR2 SMAD7 TGFB1 SMAD2 FKBP1A	down	*
GO_CELL_CELL_ADHESION_INVOLVED_IN_GASTRULATION	0.0021913	0.0374483	0.4317077	-0.7587263	-1.948515	9	MYADM IL1RN IL10 KLF4 MBP	down	*
GO_CARDIAC_MUSCLE_CELL_MYOBLAST_DIFFERENTIATION	0.0022150	0.0377259	0.4317077	-0.7583607	-1.947576	9	TBX2 REST SRF RBPJ NOTCH1 MYOCD NRG1 GREM1	down	*
GO_SECRETORY_GRANULE_MEMBRANE	0.0000000	0.0000025	0.7477397	-0.3504657	-1.946860	240	SIRPB1 OLR1 PECAM1 HVCN1 CD55 RAB44 CLEC12A IZUMO1 PTPRB CD44 CAV1 VAMP2 C5AR1 MANBA VAPA CD9 LAMP1 SLC11A1 LILRB3 RHOA CD36 SLC44A2 CD33 RAP1A ANPEP CAV2 STOM LAIR1 SIRPA CD93 LAMTOR3 RAB14 CD58 FABP5 BST1 PTAFR PLAUR GAA STX3 ATP6V1D ABCC4 TMBIM1 ITGAX PTPRC SELL SELP CD53 FCER1G DEGS1 CMTM6 HGSNAT RAB6A NCKAP1L PRCP PSEN1 PHACTR2 SNAP23 CYB5R1 RAB31 TYROBP ATP11A RHOG ENPP4 GLIPR1 SERPINB6 ALDH3B1 CR1 MME SIGLEC14 TMX3 DOK3 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 APLP2 LGALS3 BRI3	down	***
GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS	0.0000029	0.0002257	0.6272567	0.4518322	1.946445	120	SPICE1 CHEK2 NEK2 CCNB1 NDC80 TTK RACGAP1 STIL MSTO1 PLK1 NUF2 AURKB CENPA ESPL1 TPX2 MYBL2 PRC1 DCTN2 SPDL1 WDR62 KIF23 KIF3B MAP10 AURKA TPR POC1A FSD1 KIF11 GPSM2 MAD2L1 SPRY1 PSRC1 NUSAP1 CEP97 BIRC5 KIF2A SAPCD2 KPNB1 CEP192 TUBG1 TACC3 CDC20 TUBG2 AAAS EFHC1 CHMP4C CDK5RAP2	up	***
GO_G2_DNA_DAMAGE_CHECKPOINT	0.0003072	0.0092652	0.4984931	0.6235385	1.945639	23	HMGA2 BRCA1 BRSK1 PLK1 DTL CDK5RAP3 CLSPN CHEK1 BLM CDK1 FZR1 UIMC1	up	**
GO_PHAGOCYTIC_VESICLE_MEMBRANE	0.0003524	0.0102905	0.4984931	-0.4502292	-1.943412	57	RAB11FIP1 MCOLN1 HVCN1 LAMP1 SLC11A1 RILP ATP6V0D2 ANXA3 VAMP3 INPP5B SNAP23 RAB8B RAB31 RAC2 ATP6V0B RAPGEF1 RAB8A ATP6V0D1 PIK3C3 ATP6V0C RAB5A CYBA ATP6V0A1	down	*
GO_DNA_UNWINDING_INVOLVED_IN_DNA_REPLICATION	0.0002453	0.0079170	0.4984931	0.7249614	1.942954	14	MCM4 MCM2 MCM7 BLM RECQL5 SSBP1 RECQL4 HMGA1 RPA1 MCM6 RAD51	up	**
GO_PROTEIN_LOCALIZATION_TO_MICROTUBULE_ORGANIZING_CENTER	0.0001628	0.0056122	0.5188481	0.5902405	1.941558	30	CEP72 NUDCD3 CCDC14 STIL GOLGB1 DCTN2 CEP250 BICD1 AURKA C2CD3 KIAA0753 SPAG5 CEP192	up	**
GO_ATPASE_ACTIVITY_COUPLED	0.0000000	0.0000011	0.7614608	0.4137661	1.940994	257	KIF1A DDX11 HELLS DDX12P RUVBL1 CDC45 DNAH2 POLQ KIF18B TTF2 PIF1 GINS1 KIF14 FIGNL1 MCM4 MCM2 RAD54B DNAH3 XRCC2 DYNC1I1 MCM8 GINS4 DNAH14 DNAI1 RUVBL2 TNNT2 HLTF KIF3B TOP2A MYO10 SMARCAL1 MCM7 WDR78 HELB RAD54L KIF11 MCM3 PEX6 WDR60 CHD6 DNAH8 DSCC1 DNAH11 BRIP1 BLM ERCC2 MNAT1 RECQL5 DDX56 NSF DDX51 DNAH6 KIF5A NAV2 DHX37 KIF19 DNA2 DHX33 DYNLL2 DNAH5 PSMC4 RECQL4 DHX34 MOV10 DNAH7 DHX40 LONP1 RAD51D CHTF18 GINS2 KIF20B CHD5 ATAD5 RAD50 EP400 WDR34 FANCM MCM6 CHTF8 DHX8 MCM5 DNAI2 ZRANB3 DDX23 DYNC2H1 KATNB1 IGHMBP2 MYH3 DDX55 MSH4 MSH2 SMARCA4 DDX54 RTEL1 RFC5 DNAH1 RAD51 SNRNP200 CHD3 SRCAP DDX52 HSPA7	up	***
GO_SIALIC_ACID_BINDING	0.0018855	0.0340607	0.4550599	-0.7856866	-1.938463	8	SIGLEC11 FCN1 CD22 CD33 SELP	down	*
GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY	0.0000590	0.0025783	0.5573322	0.5337494	1.938289	48	KIF1A DNAH2 KIF18B KIF14 DNAH3 DYNC1I1 DNAH14 DNAI1 KIF3B WDR78 KIF11 WDR60 DNAH8 DNAH11 DNAH6 KIF5A KIF19 DYNLL2 DNAH5 DNAH7 KIF20B WDR34 DNAI2 DYNC2H1	up	**
GO_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS	0.0011890	0.0246731	0.4550599	-0.5589727	-1.936945	24	SPN TNFRSF8 CLEC7A HSPB1 IL10 THBS1 TLR4 PSEN1 TYROBP	down	*
GO_PHAGOCYTIC_VESICLE	0.0000049	0.0003514	0.6105269	-0.3985936	-1.936158	110	RAB11FIP1 MCOLN1 SCIMP HVCN1 CDC42EP2 CDC42 NCF2 LAMP1 SLC11A1 CD36 RILP RAP1A RAB14 RAB12 MPEG1 VIM ATP6V0D2 ANXA3 SNX3 MYO1C VAMP3 INPP5B SNAP23 APPL1 RAB8B RAB31 RAC2 ATP6V0B RAPGEF1 RAB8A UNC13B UVRAG ATP6V0D1 STXBP3 PIK3C3 ATP6V0C STX12 SYT11	down	***
GO_NEUTROPHIL_HOMEOSTASIS	0.0009775	0.0218185	0.4550599	-0.6389415	-1.935866	16	HCAR2 ANXA1 SH2B3 SLC7A11 JAM3 MPL AXL IL6	down	*
GO_BMP_BINDING	0.0019759	0.0349449	0.4317077	-0.7839110	-1.934082	8	SOSTDC1 GREM2 ENG BMPR2 TCAP	down	*
GO_INTERLEUKIN_6_MEDIATED_SIGNALING_PATHWAY	0.0016731	0.0315035	0.4550599	-0.6068315	-1.933897	19	CBL SPI1 CEBPA IL6 SOCS3 JAK1 SMAD4 CTR9 C1QTNF4 FER JAK2 IL6ST STAT3 IL6R PTPN11 STAT1	down	*
GO_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE	0.0000759	0.0031399	0.5384341	0.5193447	1.931024	54	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB ESPL1 CDC6 CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 ANAPC5 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 CDC20 CDK5RAP2	up	**
GO_MRNA_TRANSCRIPTION	0.0009585	0.0214893	0.4772708	-0.5806297	-1.930149	21	EREG SOX18 LMO2 SOX17 C5AR1 HIPK3 SRF DDX5 ZBTB1	down	*
GO_MITOTIC_SPINDLE_ASSEMBLY	0.0001772	0.0060370	0.5188481	0.5291568	1.929831	49	SPICE1 CHEK2 NEK2 RACGAP1 MSTO1 PLK1 AURKB TPX2 MYBL2 KIF23 KIF3B MAP10 TPR KIF11 CEP97 BIRC5 KIF2A KPNB1 CEP192 CDC20 AAAS CHMP4C CHMP1A CHMP2A GOLGA2 MAP9 CLASP1 DRG1 WRAP73	up	**
GO_PRI_MIRNA_TRANSCRIPTION_BY_RNA_POLYMERASE_II	0.0003849	0.0110175	0.4984931	-0.4760124	-1.928476	42	SMAD6 PPARG GATA2 BMP2 FOSL1 NR3C1 NFATC3 SPI1 IL10 KLF4 TGFB2 SRF JUN ETS1 DDX5 FOS TGFB1	down	*
GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION	0.0000775	0.0031778	0.5384341	0.5186447	1.928421	54	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 CDT1 SPDL1 FBXO43 BUB1 TPR MAD1L1 TOM1L1 HORMAD1 CHEK1 MAD2L1 MTBP MAD2L2 KLHL22	up	**
GO_POSITIVE_REGULATION_OF_ERAD_PATHWAY	0.0030628	0.0476783	0.4317077	-0.6709989	-1.927724	13	ATXN3 CAV1 EDEM1 NFE2L2 RNFT1 UBQLN1	down	*
GO_DOUBLE_STRAND_BREAK_REPAIR_VIA_BREAK_INDUCED_REPLICATION	0.0004380	0.0122630	0.4984931	0.7647256	1.926367	11	CDC45 MCM4 MCM2 GINS4 MCM7 MCM3 GINS2 CDC7 MCM6 MCM5	up	*
GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION	0.0000308	0.0015523	0.5573322	0.4921103	1.926066	70	TRIP13 DDX11 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDC6 CDT1 SPDL1 BUB1 TPR MAD1L1 CDCA5 MAD2L1 ANAPC5 FEN1 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 CDC20 CDK5RAP2	up	**
GO_REGULATION_OF_WATER_LOSS_VIA_SKIN	0.0003113	0.0093623	0.4984931	0.6450132	1.925520	20	TP63 FA2H ABCA12 KRT16 LSR GRHL3 CLDN1 HRNR FLG TMEM79	up	**
GO_MAP_KINASE_PHOSPHATASE_ACTIVITY	0.0031126	0.0477205	0.4317077	-0.6700869	-1.925103	13	DUSP3 DUSP1 DUSP8 DUSP5 PP2D1 DUSP7 DUSP6 DUSP2 DUSP10	down	*
GO_LEUKOCYTE_ACTIVATION_INVOLVED_IN_INFLAMMATORY_RESPONSE	0.0011481	0.0241867	0.4550599	-0.4880865	-1.924346	37	C5AR1 GRN CCL3 PTPRC IL6 C1QA JUN TYROBP IFNGR1 CST7 FPR2 SYT11 CTSC LDLR SPHK1 TREM2 TRPV1 IFNG JAK2 TLR3 ITGAM SNCA NAMPT ITGB2 NR1D1 IL33 MAPT MIR142	down	*
GO_ENDOCRINE_HORMONE_SECRETION	0.0007478	0.0181304	0.4772708	-0.5191755	-1.923520	30	RAB11FIP1 TBX3 IL1B HCAR2 FZD4 GATA3 TACR2 INHBA RAB8B CRY1 FGFR1 SMAD4	down	*
GO_POSITIVE_REGULATION_OF_INTEGRIN_MEDIATED_SIGNALING_PATHWAY	0.0008093	0.0190862	0.4772708	-0.8171299	-1.923272	7	LIMS2 EMP2 LIMS1	down	*
GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION	0.0023878	0.0397462	0.4317077	-0.6520532	-1.921674	14	ACP5 IL10 MEFV THBS1 NFKB1 TIGIT ARRB2	down	*
GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_CENTROMERIC_REGION	0.0007652	0.0183268	0.4772708	0.6520818	1.921163	19	NDC80 TTK AURKB CENPA CDT1 SPDL1 BOD1 CDK1 TRAPPC12 MTBP CENPQ	up	*
GO_ENDOTHELIUM_DEVELOPMENT	0.0000213	0.0011768	0.5756103	-0.3900935	-1.918821	112	TMEM100 ACVRL1 SOX18 PECAM1 IL1B RDX RAPGEF2 CDH5 ENG SOX17 MYADM BMPR2 S1PR1 HEG1 RHOA PDE2A RAP1A FOXP1 ZEB1 PDE4D FOXC2 RHOB ROCK2 ROCK1 TJP1 CLDN5 CLIC4 ITGAX ARHGEF26 ADD1 BTG1 RBPJ	down	**
GO_CENTRIOLE	0.0000136	0.0008085	0.5933255	0.4500475	1.915548	111	SPICE1 MDM1 CEP89 MKS1 STIL PLK1 CCNF WDR90 CEP250 WDR62 CEP55 TSGA10 TOP2A FBF1 AURKA ODF2 SFI1 POC1A AGBL4 MPHOSPH9 CBY1 C2CD3 CCDC78 IQCB1 CROCC CENPJ KIAA0753 POC5 KIF2A POC1B FGFR1OP IFT52 CEP63 CEP192 TUBG1 CCDC151 CCDC146 CEP128 SASS6 AGBL2 WDR34 FTCD ODF2L NEURL4 CEP152 ALMS1 CEP164 NUBP2 KIF24 KIAA0586 CEP290 WRAP73 PLK4 FAM92B PCNT RILPL1 DZIP1	up	***
GO_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ASSEMBLY	0.0004763	0.0131514	0.4984931	-0.4434126	-1.913988	57	ACVRL1 TEK DLC1 WNT4 CORO1C RHOA APOD SFRP1 ROCK2 DUSP3 LIMS1 ROCK1 THBS1 PEAK1 FAM107A MAP4K4 PPM1F EPHA3 CLASP2 MACF1 EPB41L5 LIMCH1 PTEN IQGAP1 GREM1	down	*
GO_CILIARY_TIP	0.0002686	0.0084328	0.4984931	0.5443946	1.913790	40	IFT122 TTC26 IFT27 KIF3B IFT43 WDR60 IFT172 KIF3C KIF7 DYNLL2 SMO IFT52 TRAF3IP1 WDR34 WDR35 DYNC2H1 ICK CLUAP1 TTC30B GLI3 KIFAP3 KIF3A IFT81 IFT74	up	**
GO_NEGATIVE_REGULATION_OF_LIPID_LOCALIZATION	0.0009013	0.0206653	0.4772708	-0.5029839	-1.913431	34	ABHD5 PPARG PLA2G10 PCSK9 MIR27B MIR146A ABCG1 APOC1 THBS1 NFKB1 IL6 PNPLA2 IRS2 CRY1 SREBF2 NFKBIA	down	*
GO_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY	0.0003589	0.0104524	0.4984931	-0.4557082	-1.912813	49	SASH1 SCIMP CD55 IL1B LY86 TRIB1 CD36 CARD16 TRAF6 PTAFR LY96 CCL3 IRAK2 TLR4 HCK CARD8 PRKCE MALT1 TGFB1 CD6 IL18 RIPK2 NFKBIA	down	*
GO_CALCITONIN_FAMILY_RECEPTOR_COMPLEX	0.0000479	0.0021772	0.5573322	-0.9648766	-1.911821	4	RAMP3 RAMP2 CALCRL	down	**
GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0000002	0.0000251	0.6901325	0.4216063	1.911713	183	HMGA2 CEP72 TICRR NEK2 CCNB1 CENPF STOX1 BRCA1 CDK4 BRSK1 GTSE1 DBF4B KIF14 CEP70 PLK1 AURKB CDC6 TPX2 CDC25A ORC1 DTL ZFYVE19 CDK5RAP3 DCTN2 HAUS5 CEP250 HMMR SMARCD3 AURKA ODF2 SFI1 CLSPN CDC25C TOPBP1 CHEK1 PSMD4 BLM CDK1 CENPJ PSMB5 PSMC4 FGFR1OP CEP63 CEP192 TUBG1 NEK10 PSMA5 NINL PSME2 MTA3 FZR1 PSMD2 ATAD5 CDC7 CKAP5 PSMB3 CHMP4C WNT10B CDK5RAP2 UIMC1 HAUS6 HAUS4 PSMB4 CEP152 ALMS1 CEP164 PAXIP1 TP53 CDC25B CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT FBXO5 PSMB10 PSME1 NPM1 RCC2 NAE1 BRD4 TAOK2 CTC1 PSMD3 PPP2R1A RBX1 VPS4A PSMD8 DCTN3	up	***
GO_HELICASE_ACTIVITY	0.0000017	0.0001507	0.6435518	0.4352667	1.911414	138	DDX11 HELLS DDX12P RUVBL1 CDC45 POLQ TTF2 PIF1 GINS1 MCM4 MCM2 RAD54B MCM8 GINS4 RUVBL2 HLTF SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 RECQL5 DDX56 DDX51 NAV2 DHX37 DNA2 DHX33 RECQL4 DHX34 MOV10 DHX40 CHTF18 GINS2 CHD5 RAD50 EP400 FANCM MCM6 CHTF8 DHX8 MCM5 DDX23 IGHMBP2 DDX55 SMARCA4 DDX54 RTEL1 RFC5 RAD51 SNRNP200 CHD3 SRCAP DDX52	up	***
GO_REGULATION_OF_MODIFICATION_OF_SYNAPTIC_STRUCTURE	0.0014171	0.0278854	0.4550599	-0.7179135	-1.910653	10	BAIAP2 CDC42 RHOA CTTNBP2 TIAM1 EPHA4	down	*
GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.0003024	0.0091474	0.4984931	-0.4375275	-1.910274	60	ANGPT4 ACVRL1 PPARG CORO1C TBXA2R RHOA MIR146A MMRN2 PTPRM ADIPOR1 RGCC KLF4 THBS1 ADAMTS9 MIR24-2 NOTCH1 EPPK1 TGFB1 FGF2 VASH1 SP100 PTEN STARD13 MIR640 MIR2355 ANGPT2 HMGB1	down	**
GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION	0.0012303	0.0252387	0.4550599	-0.5361568	-1.909600	26	IL1RL1 GAS6 GATA3 IL10 AXL TLR4 MIR24-2 INHBA	down	*
GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	0.0000288	0.0014641	0.5756103	-0.3975094	-1.908758	95	ANGPT4 SASH1 HMOX1 TEK GATA2 BMPR2 MIR27B ANXA1 MIR146A ADAM17 HSPB1 FOXP1 GATA3 NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 THBS1 PIK3C2A NUS1 ANXA3	down	**
GO_REGULATION_OF_RESPONSE_TO_WOUNDING	0.0000035	0.0002637	0.6272567	-0.3685981	-1.908728	145	TNR AJAP1 ADTRP WFDC1 WNT4 THBD CAV1 TBXA2R HMGCR CD9 TGFBR2 SCARF1 CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 CLEC7A ANXA5 NFE2L2 NDEL1 GRN CRK PDGFA FOXC2 IL10 KLF4 PLAUR THBS1 CDKN1A SELP HPSE TLR4 FCER1G PLEK UBASH3B KREMEN1 STK24 KANK1 CNTF DUOX1 ENPP4 PRKCE RTN4R CD34 SRSF6 EPPK1	down	***
GO_INTERLEUKIN_6_PRODUCTION	0.0000276	0.0014330	0.5756103	-0.3879139	-1.908100	112	EREG IL1A SCIMP SIGLEC16 IL1B LPL MYD88 IL1RN GAS6 CD36 MIR146A CLEC7A SIRPA TRAF6 ARHGEF2 IL10 ARRB1 PTAFR SOCS5 TLR4 FCER1G NCKAP1L IL17D IL6 TYROBP KLF2 AZI2 MBP CD74 AKIRIN2 SYT11 IL18 IL18RAP ARRB2 RIPK2 HAVCR2 BANK1 CYBA C5AR2 TREM2 TBC1D23 WNT5A BCL10 HMGB1	down	**
GO_REGULATION_OF_DNA_REPAIR	0.0000352	0.0017312	0.5573322	0.4580959	1.907916	96	HMGA2 DDX11 FOXM1 EYA1 PARPBP EYA2 TIMELESS POLQ BRCA1 NPAS2 WDR70 FIGNL1 MAGEF1 TP53BP1 AUNIP PRKDC HELB EGFR CHEK1 RAD51AP1 XRCC1 PML RECQL5 PARP1 MAD2L2 MGMT NUDT16 PARP9 UBQLN4 TWIST1 UBE2V2 WRNIP1 UIMC1 DTX3L RTEL1 RAD51 EYA4 NUDT16L1 SIRT6 PARG	up	**
GO_HEMIDESMOSOME_ASSEMBLY	0.0003296	0.0097105	0.4984931	0.7793763	1.907859	10	COL17A1 KRT5 LAMC2 ITGB4	up	**
GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_PROLIFERATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0030959	0.0477205	0.4317077	-0.6969769	-1.907075	11	HMOX1 GATA2 MIR27B MIR146A	down	*
GO_BMP_RECEPTOR_ACTIVITY	0.0003936	0.0112050	0.4984931	-0.8959766	-1.906972	5	ACVRL1 SOSTDC1 BMPR2	down	*
GO_MYELOID_LEUKOCYTE_ACTIVATION	0.0000000	0.0000000	0.9436322	-0.3190075	-1.906594	535	SIRPB1 SLPI CD300LF FOXF1 HMOX1 FCN1 OLR1 PECAM1 HVCN1 CD55 GATA2 MNDA LTA4H DCSTAMP CAT RAB44 CLEC12A PLA2G10 PTPRB OSCAR CD44 PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA IL1RL1 VAPA FUCA1 LAMP1 CBL SLC11A1 TGFBR2 LILRB3 FGR RHOA DNASE1L3 CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ASAH1 RAP1A GM2A FOXP1 ANPEP PTX3 STOM LAIR1 SIRPA TRAF6 CD93 GRN LAMTOR3 SPI1 RAB14 CD58 CST3 SLC7A2 IL10 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 THBS1 CEBPA ATP6V1D CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE TLR4 ARHGAP9 CD53 FCER1G GCA DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP RBPJ IL6 CTSS PSEN1 SNAP23 C1QA JUN VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG IFNGR1 ENPP4 GLIPR1 GMFG PRKCE SERPINB6 CAP1 SUCNR1 CST7 PSMD12 ALDH3B1 TREX1 CD74 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 DOK3 JMJD6 MILR1 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ORM2 BRI3 PLEKHO2 ADAM10 IST1 SYT11 COMMD9 UNC13D IL18 IL18RAP LAT HSP90AA1 HSPA8 HAVCR2 METTL7A NHLRC3 KIT SIGLEC9 CTSC ARPC5 SNAP29 P2RX1 RORA LDLR PSMD6 IQGAP1 CREG1 CNN2 ANO6 LYZ SPHK1 CSF2 CYBA ATP6V0A1 CTSH CNR2 TMEM30A ATP11B MAPK1 ITGAL TREM2 FTL S100A8 RAB37 FPR1 KMT2E NFAM1 PIK3CG	down	***
GO_NEGATIVE_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION	0.0005684	0.0149998	0.4772708	0.7564348	1.905482	11	PARPBP POLQ MAGEF1 TP53BP1 HELB RECQL5 MAD2L2 UBQLN4	up	*
GO_CENTROMERE_COMPLEX_ASSEMBLY	0.0002761	0.0085831	0.4984931	0.5579574	1.904635	34	HELLS HJURP RUVBL1 CENPF CENPA MIS18A CENPL CENPW CENPO CENPH TRAPPC12 CENPP CENPQ CENPK CENPV CENPM CENPT	up	**
GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION	0.0005768	0.0151311	0.4772708	-0.4993050	-1.901055	33	ACVRL1 PPARG CAV1 MIR146A PTPRM CAV2 RGCC THBS1 MIR24-2 FLT1	down	*
GO_RESPONSE_TO_CGMP	0.0004968	0.0136069	0.4772708	-0.8926946	-1.899987	5	SLC6A4 RAPGEF2 PDE2A	down	*
GO_CHROMOSOME_SEPARATION	0.0000280	0.0014417	0.5756103	0.4716443	1.898890	81	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDC6 NCAPD2 CDT1 SPDL1 BUB1 TOP2A EME1 TPR MAD1L1 EME2 MAD2L1 RECQL5 ANAPC5 DIS3L2 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 SLX4 CDC20 FANCM CDK5RAP2	up	**
GO_REGULATION_OF_CHROMOSOME_SEPARATION	0.0001267	0.0046203	0.5188481	0.4994941	1.897970	59	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDC6 CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 ANAPC5 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 CDC20 CDK5RAP2	up	**
GO_POSITIVE_REGULATION_OF_URINE_VOLUME	0.0017375	0.0323672	0.4550599	-0.7131130	-1.897877	10	EDNRB INPP5K NPR3 GNAI2 NPR1 ADORA2A EDN1 HAS2	down	*
GO_REGULATION_OF_VASCULATURE_DEVELOPMENT	0.0000000	0.0000023	0.7477397	-0.3363139	-1.896895	276	ANGPT4 SEMA6A TMEM100 ACVRL1 IL1A SASH1 HMOX1 TEK PPARG HHEX GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 CDH5 ENG ECSCR GTF2I TBXA2R C5AR1 MIR27B TGFBR2 NFATC3 HSPG2 RHOA ANXA1 MIR146A MMRN2 PTPRM RAP1A ITGA5 HSPB1 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 FOXC2 NODAL RHOB GPR4 IL10 ROCK2 TNFSF12 TSPAN12 KLF4 ROCK1 THBS1 ADAMTS9 CLDN5 PDE3B ITGAX MIR24-2 RECK PIK3C2A PTGIS ANXA3 TGFB2 BTG1 FLT1 IL6 CD160 NOTCH1 ETS1 JAK1 RHOJ NPR1 CD34 RRAS KLF2 ISM1 MIR23A SOD2 MYOCD GATA6 ADAM10 FGF2 VASH1 EPN2 SEMA4A CXCR4 SP100 EPHA2 GLUL RAPGEF3 KIT FOXJ2 RNH1 SPHK1 STARD13 EGR1 GREM1 SERPINE1 CTSH HIPK1 ATF2 CX3CR1 C5 ITGB1 MIR640 MIR2355 EFNB2 HEY1	down	***
GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_BINDING	0.0032100	0.0487703	0.4317077	-0.6736783	-1.895528	12	SMAD6 BMP2 CDH5 NODAL INHBA MAGI2 BMP3	down	*
GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY	0.0000649	0.0027640	0.5384341	-0.4032372	-1.893600	81	SWAP70 DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 INPP5K BAG4 S1PR1 CDC42 RHOA RGCC SFRP1 SORBS3 ROCK2 SYNPO ROCK1 PLEK WASF2 SYNPO2 ARHGEF10 PTGER4 PIK3R1 PPM1F WNT11	down	**
GO_PEPTIDYL_SERINE_DEPHOSPHORYLATION	0.0010417	0.0228983	0.4550599	-0.5806523	-1.893512	20	SWAP70 PPP1R15B PPP2R2A PPP3CA DUSP1 PPP2CA PPP1R15A PPM1F PPTC7 PPP2CB	down	*
GO_CORECEPTOR_ACTIVITY	0.0009973	0.0221647	0.4550599	-0.4851341	-1.893349	36	RAMP3 GPR15 RAMP2 TGFBR3 CD8A LY96 RECK CD8B CD80 ACKR3 CD86 CXCR4 FCRL1 ITGB1 LRP1 CD4	down	*
GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT	0.0019003	0.0340850	0.4550599	-0.5400983	-1.892683	25	TEK PECAM1 FOXC2 GPR4 HES1 NOTCH1 CD34 PKD2 OSR1 EGR1 ANGPT2 CFLAR	down	*
GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_PHOSPHATASE_ACTIVITY	0.0010553	0.0229576	0.4550599	-0.5803969	-1.892679	20	FIG4 INPP5K PTPMT1 MTMR6 SACM1L INPP5B PIKFYVE MTMR14 MTMR2 PTEN	down	*
GO_CENTRIOLE_ASSEMBLY	0.0002800	0.0086790	0.4984931	0.5611338	1.891946	33	MCIDAS CEP72 SPICE1 MDM1 BRCA1 STIL WDR62 C2CD3 CCDC78 CENPJ KIAA0753 CEP63 TRIM37 SASS6 CDK5RAP2 CEP152 NUP62 ALMS1 CHMP2A PLK4 NPM1 CNTROB E2F4	up	**
GO_DNA_REPAIR	0.0000000	0.0000000	0.8753251	0.3849952	1.891771	448	HMGA2 TRIP13 DDX11 FOXM1 EYA1 RUVBL1 CDC45 TICRR PARPBP FANCI CHEK2 EYA2 TIMELESS POLQ UBE2T PAGR1 PIF1 BRCA1 NPAS2 PMS2P5 POLE NABP2 PTTG1 WDR70 FIGNL1 RBBP8 UHRF1 MCM4 MCM2 RAD54B PMS2 XRCC2 DTL CIB1 MCM8 LIG3 GINS4 SMUG1 MAGEF1 RUVBL2 EXO1 NUDT1 CHAF1A TP53BP1 POLM RHNO1 FANCA AUNIP EME1 REC8 ATR POLD2 SMARCAL1 MCM7 ASCC2 CLSPN MMS22L CDCA5 PRKDC TRRAP WDHD1 HELB RAD54L FANCD2 MCM3 CHAF1B EGFR LIG1 EME2 TOPBP1 CHEK1 ACTL6A RAD51AP1 XRCC1 PRMT6 BRIP1 RAD18 BLM PPP5C PML ERCC2 MNAT1 RECQL5 PARP1 POLN CDK1 POLE2 RFWD3 EEPD1 UNG DNA2 AP5Z1 NEIL3 FEN1 MAD2L2 RECQL4 RNASEH2A POLR2H FANCG DCLRE1C FANCF POLL MBD4 RAD9A MC1R KIF22 RAD51D SSRP1 COPS7B ESCO2 MGMT GINS2 FZR1 NUDT16 TCEA1 USP43 POLD1 POLB PARP9 COPS6 SLX4 CDC7 RAD50 UBQLN4 SUPT16H PALB2 TWIST1 HMGA1 ASCC1 RPA1 POLR2J FANCM UBE2V2 MCM6 MGME1 WRNIP1 XRCC4 MCM5 TDP1 ZRANB3 UIMC1 POLR2I IGHMBP2 PMS2P1 MSH4 PMS1 MCRS1 MSH2 NFRKB DTX3L RTEL1 RFC5 CEP164 INO80E RAD51 TNKS1BP1 EYA4 PAXIP1 NUDT16L1 SIRT6 PNKP TONSL PARG XPC MPG SWI5 TP53 NEIL1 APEX1 RAD1 DDB2 PIAS4 ACTR5 TMEM161A ERCC3 ALKBH2 PARP2 TTC5	up	***
GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY	0.0000240	0.0013026	0.5756103	0.4571032	1.891749	94	HMGA2 HELLS HJURP RUVBL1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A SMARCD3 SMARCC1 CHAF1A CENPL TPR CENPW CHAF1B CENPO ASF1B CENPH CENPP HIRA CENPQ NOC2L CENPK SUPT16H CENPV CENPM HMGA1 CENPT NFE2 SMARCC2 SUV39H2 SMARCA4 CHD3 SIRT6 TP53 SMARCB1 SART3	up	**
GO_POSITIVE_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_BY_RNA_POLYMERASE_II	0.0014895	0.0291393	0.4550599	-0.5303772	-1.889015	26	SMAD6 GATA2 BMP2 NR3C1 SPI1 IL10 TGFB2 SRF JUN FOS TGFB1	down	*
GO_ORGANELLE_FISSION	0.0000000	0.0000001	0.8140358	0.3891280	1.888916	365	TRIP13 SPICE1 CHEK2 BUB1B NEK2 CCNB1 CENPF MND1 KIF18B NDC80 TTK SMPD3 RACGAP1 KIF14 L3MBTL1 ANLN ASPM MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 ACOT8 TPX2 FIGNL1 RAD54B MYBL2 PRC1 TDRKH NCAPD2 ZWINT CDT1 SPDL1 RANBP1 KIF23 STAG3 MKI67 CUL9 BOD1 CUL7 FBXO43 KNTC1 KIF3B BUB1 FANCA MSX2 TOP2A MAP10 AURKA EME1 REC8 SYCP2 TPR KIF2C MAD1L1 MSX1 CDCA5 RAD54L TOM1L1 KIF11 FANCD2 HORMAD1 CDC25C EME2 CHEK1 MAD2L1 DSCC1 PKMYT1 BRIP1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 CEP97 BIRC5 SUN1 DIS3L2 NCAPG STAT2 KIF2A SPAG5 EGF MTBP MAD2L2 KLHL22 KPNB1 MYO19 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 SEC16B TACC3 DHODH KIF22 HIRA RAD51D DNM1 AKAP8L FZR1 KIF20B ANAPC1 CDK13 COX10 SLX4 RAD50 ANKRD31 CENPK KLHDC3 SH2B1 MEI1 CDC20 TUBG2 AAAS CHMP4C FANCM CDK5RAP2 CHTF8 KATNB1 RCC1 PRMT5 NUP62 CEP85 MSH4 RAD51 CHMP1A CHMP2A AURKAIP1 SMC2 LIF MAU2 CENPE GOLGA2 FIS1 CDC25B UBE2C NCAPD3 MAP9 RAD1 RRS1 DNM1L CLASP1 NCAPH POGZ CHMP6 PDXP MUS81 DRG1 MLH3 WRAP73 C11orf80 DSN1 PEX11A FBXO5 LCMT1 NFE2L1 OPA1 NSL1 SLC2A8 MAD2L1BP	up	***
GO_GLUCOSE_CATABOLIC_PROCESS	0.0010625	0.0229576	0.4550599	0.5924731	1.888684	25	PGM2L1 GPI GAPDH ALDOC PKM PFKP ALDOA ALDOB BPGM FOXK1 BAD HK2 PFKM PGAM1 TP53 ENO1	up	*
GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT	0.0000000	0.0000000	0.9969862	-0.3117646	-1.887038	616	SMAD6 ANGPT4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB CDH5 ENG LYL1 ARHGEF15 FOLR1 ECSCR SOX17 CAV1 FOSL1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 NFATC3 HSPG2 HEG1 RHOA PDE2A APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM RAP1A TMEM204 ITGA5 CLEC14A HSPB1 LUZP1 FZD4 ANPEP NR4A1 JAM3 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 SPI1 TCF7L2 PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 MMP21 ROCK2 AMOTL1 NRARP FOXO1 TBX4 TNFSF12 TSPAN12 KLF4 ROCK1 ZFAND5 THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HPSE MIR24-2 RECK PIK3C2A ELK3 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS HES1 PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ FLT1 IL6 WASF2 PKNOX1 CD160 PSEN1 SOCS3 NDNF JUN NOTCH1 ETS1 JUNB EPC1 JAK1 RHOJ RAPGEF1 ACKR3 NPR1 NDST1 MCAM CD34 POGLUT1 RRAS KLF2 GJA4 PKD2 TREX1 WNT11 TGFB1 VAV3 ISM1 JMJD6 MIR23A MIA3 COL15A1 SOD2 MEIS1 MYOCD GATA6 GNA13 LTBP1 ADAM10 FGF2 IL18 VASH1 EGFL7 EPN2 OSR1 SEMA4A CXCR4 SP100 EPHA2 PARVA GLUL STK4 RAPGEF3 KIT EDN1 ETV2 FOXJ2 PTEN FGFR1 RORA LDLR NRP2 NAA15 ZFPM2 RNH1 FLT4 SPHK1 STARD13 EGR1 GREM1 SERPINE1 CTSH GJC1 HIPK1 ATF2 CX3CR1 C5 MAPK1 MYH10 ITGB1 HAS2 NOG MIR640 MIR2355 EFNB2 PIK3CG HEY1	down	***
GO_FICOLIN_1_RICH_GRANULE_MEMBRANE	0.0005361	0.0144102	0.4772708	-0.4571290	-1.886894	46	CD55 LAMP1 SLC11A1 RHOA SIRPA CD93 CD58 GAA ITGAX FCER1G NCKAP1L PRCP ENPP4 SERPINB6 CR1 SIGLEC14 DOK3 FPR2 DYNC1LI1 ATP6V0C LGALS3	down	*
GO_HISTONE_KINASE_ACTIVITY	0.0005994	0.0154183	0.4772708	0.7039762	1.886712	14	CCNB1 AURKB PRKCA AURKA CHEK1 CDK1 PRKAA2	up	*
GO_SISTER_CHROMATID_COHESION	0.0003235	0.0096433	0.4984931	0.5277669	1.885802	44	DDX11 DDX12P STAG3L2 BUB1B PLK1 ESPL1 STAG3 BOD1 BUB1 REC8 CDCA5 HORMAD1 DSCC1 FEN1 KIF22 ESCO2 STAG3L4 CDC20 CHTF8	up	**
GO_HEAT_GENERATION	0.0030540	0.0476143	0.4317077	-0.6373490	-1.878339	14	IL1A EDNRB IL1B ADRB1 ADRB2 PTGER3	down	*
GO_MICROTUBULE_BASED_MOVEMENT	0.0000001	0.0000125	0.7049757	0.4021187	1.878179	239	KIF1A KIF12 KLC3 KIF20A DNAH2 AP3B2 UCHL1 KIF18B STK36 RACGAP1 IFT122 KIF14 SPAG17 TTC26 IFT27 DNAH3 DYNC1I1 KIF27 DNAH14 DNAI1 ARMC4 KIF23 BICD1 KIF15 COPG2 COPG1 KIF3B IFT43 KIF2C HYDIN WDR78 DPCD TEKT2 CCDC114 KIF11 BLOC1S1 WDR66 WDR60 NME5 DNAH8 IFT172 GAS8 KIF3C DNAH11 CCDC40 DRC1 KIAA0556 LRRC6 DNAH6 KIF5A AP3D1 SUN1 KIF19 KIF2A KIF7 SSX2IP DYNLL2 LCA5 DNAH5 IFT52 KPNB1 DLGAP5 SPG7 DNAH7 CCDC151 KIF22 KIF21A KIF20B TEKT3 SPA17 TRAF3IP1 KLC2 WDR34 AP3M2 DYNC1LI2 KIF21B DNAI2 WDR35 DYNC2H1 KATNB1 TTLL6 RSPH4A NEFH CATSPER1 SYBU ICK CLUAP1 DNAH1 TRAK1 RHOT2 CELSR2 MAPK8IP3 CAMSAP3 CENPE DTNBP1 SYNE2 TTC30B RASGRP1 TMEM201 KIF24 DNAL4 DNAAF1 DYNC1H1 MAK TEKT1 WDR63	up	***
GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE	0.0000024	0.0001961	0.6272567	-0.3636111	-1.875699	153	FFAR4 HCRTR1 RAMP3 TEK SCIMP GLIPR2 P2RY1 RAPGEF2 BMPER BMP2 CD44 CCL3L1 C5AR1 HMGCR FGF10 MIR27B MARCO GAS6 CD36 RAP1A SPRY2 PDGFA NODAL ARRB1 CCL22 NPNT PDE8A CCL3 PTPRC CCL4 TLR4 MIR24-2 XCL2 GNAI2 DNAJC27 JUN NOTCH1 ADRA1A RAPGEF1 CCR7 ACKR3 GPR183 FGFR4 CD74 TGFB1 FPR2 MIR23A NQO2 CCR1 NPTN CCL20 ICAM1 FGF2 ARRB2 RIPK2 HAVCR2	down	***
GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION	0.0000012	0.0001125	0.6435518	0.4141497	1.875598	179	HELLS HJURP RUVBL1 CDC45 CENPF CABIN1 TSPYL5 CENPA SOX9 MCM4 MCM2 MIS18A CAND1 CDT1 SMARCD3 SMARCC1 CHAF1A CENPL MCM7 CENPW MCM3 CHAF1B ZNHIT1 CENPO PIH1D1 ERCC2 MNAT1 PARP1 ASF1B CENPH GMNN GTF2E1 TAF6 TRAPPC12 PSMC4 VPS72 CENPP HIRA CENPQ ANP32E CHD5 ESR1 CENPK BAZ2A SUPT16H CENPV HNF1B CENPM HMGA1 RPA1 WNT10B MCM6 CENPT MCM5 NFE2 SMARCC2 SMARCA4 RAD51 GTF3C5 SOX12 XPC CENPE SRCAP SWI5 TP53 UBTF SMARCB1 ATF7IP DDB2 SART3 ERCC3 POGZ	up	***
GO_NEGATIVE_REGULATION_OF_CELL_ADHESION	0.0000000	0.0000054	0.7195128	-0.3387857	-1.874986	231	TNR DAB1 AJAP1 SEMA6A ACVRL1 SWAP70 DLC1 CCM2L ADTRP SPN LPXN RDX BMP2 CORO1C MYADM CDH13 PRKAR1A CD9 IL1RN RHOA APOD ANXA1 MIR146A SH2B3 PLXNA2 FZD4 HLX PAG1 JAM3 PLXNA4 RGCC IL10 NRARP DUSP3 PTPRO KLF4 THBS1 SOCS5 PDE3B PTPRC JAM2 SFTPD DUSP1 SMAD7 UBASH3B ARHGDIB GNRH1 KANK1 FAM107A CD80 NOTCH1 PDE5A MAP4K4 PODXL PIK3R1 RC3H1 TBX21 TIGIT PPM1F PELI1 CD164 MBP RUNX3 CD74 TGFB1 YTHDF2 LRRC32 MIA3 CD86 LGALS3 CLASP2 ADAM10	down	***
GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES	0.0000138	0.0008170	0.5933255	0.4438513	1.873095	107	CEACAM1 CDHR2 PTPRT PCDHGA10 IGSF9 CDH17 FAT2 PCDHGA9 PCDHGA5 PCDHGA7 SDK2 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 IGSF11 VSTM2L PCDHGB4 PCDHGA11 PCDHGA8 CLSTN3 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 SDK1 PCDHGA3 IGSF21 MYOT FAT1 CDH3 PCDHGA2	up	***
GO_PROTEIN_LOCALIZATION_TO_KINETOCHORE	0.0008533	0.0197861	0.4772708	0.6815299	1.869807	15	NDC80 TTK AURKB CDT1 SPDL1 CDK1 TRAPPC12 MTBP CENPQ	up	*
GO_REGULATION_OF_B_CELL_PROLIFERATION	0.0005445	0.0145599	0.4772708	-0.4375368	-1.868731	54	MNDA CD22 CLCF1 ADA WNT3A TFRC IL10 BST1 CDKN1A PTPRC TLR4 NCKAP1L TYROBP GPR183 RC3H1 PELI1 CD74 VAV3 IRS2 CD81	down	*
GO_DNA_STRAND_ELONGATION	0.0012003	0.0247726	0.4550599	0.6147604	1.867903	21	GINS1 POLE MCM4 LIG3 GINS4 POLD2 MCM7 MCM3 LIG1 DNA2 GINS2 RAD50 GINS3 DCLRE1B POT1 POLD3 RFC3 RFC4 PCNA	up	*
GO_SPINDLE_ORGANIZATION	0.0000070	0.0004672	0.6105269	0.4210124	1.867241	146	CEP72 SPICE1 CHEK2 NEK2 CCNB1 NDC80 TTK RACGAP1 ASPM STIL MSTO1 PLK1 NUF2 AURKB ESPL1 TPX2 MYBL2 PRC1 DCTN2 HAUS5 WDR62 DLG1 KIF23 KIF3B AUNIP MAP10 AURKA TPR CENPW POC1A FSD1 KIF11 GPSM2 PSRC1 KNSTRN CEP97 BIRC5 KIF2A SPAG5 KPNB1 CEP63 CEP192 TUBG1 TACC3 CKAP5 CDC20 TUBG2 AAAS EFHC1 CHMP4C HAUS6 RCC1 HAUS4 NUP62 NTMT1 TUBGCP4 CHMP1A CHMP2A CHD3 CENPE GOLGA2 MAP9 CLASP1 DRG1 DYNC1H1 WRAP73 PCNT FBXO5 TUBGCP2	up	***
GO_NEGATIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION	0.0024275	0.0401974	0.4317077	-0.7013574	-1.866591	10	GTF2I ATP2B1 KCNK3 KCNA5 SLC8A1	down	*
GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION	0.0007210	0.0177357	0.4772708	-0.4855682	-1.865563	35	CLCF1 ADA WNT3A TFRC BST1 CDKN1A PTPRC TLR4 NCKAP1L GPR183 PELI1 CD74 VAV3 IRS2 CD81	down	*
GO_CILIARY_BASAL_BODY_PLASMA_MEMBRANE_DOCKING	0.0000454	0.0020993	0.5573322	0.4578376	1.864599	86	CEP72 CEP89 RPGRIP1L NEK2 RAB3IP MKS1 CEP70 PLK1 DCTN2 HAUS5 CEP250 FBF1 ODF2 SFI1 C2CD3 IQCB1 CDK1 CEP97 CENPJ TCTN2 FGFR1OP CEP63 CEP192 NPHP1 TUBG1 NINL CKAP5 TCTN1 CDK5RAP2 HAUS6 HAUS4 CEP152 B9D1 ALMS1 CEP164 MARK4 CLASP1 KIF24 CEP290 DYNC1H1 PLK4 AKAP9 PCNT	up	**
GO_MITOTIC_DNA_REPLICATION_CHECKPOINT	0.0006408	0.0161133	0.4772708	0.7616043	1.864354	10	TICRR CDC6 ORC1 CLSPN TOPBP1	up	*
GO_REGULATION_OF_SPROUTING_ANGIOGENESIS	0.0002956	0.0089700	0.4984931	-0.4169147	-1.863549	68	SEMA6A HMOX1 GATA2 BMPER TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 ITGA5 AKT3 FOXC2 IL10 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NOTCH1 JAK1 RHOJ	down	**
GO_TISSUE_MIGRATION	0.0000000	0.0000062	0.7195128	-0.3345187	-1.863192	261	ANGPT4 ACVRL1 SASH1 FOXF1 HMOX1 SOX18 TEK PECAM1 PPARG ADTRP GLIPR2 GATA2 EMP2 BMPER CORO1C CDH13 BMPR2 TBXA2R FGF10 MIR27B TGFBR2 RHOA ZEB2 ANXA1 MIR146A MMRN2 PTPRM HBEGF ARSB ADAM17 CLEC14A HSPB1 FOXP1 ADIPOR1 GATA3 NR4A1 RGCC NFE2L2 GRN AKT3 KANK2 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 TNFSF12 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A ACTG2 NUS1 ANXA3 MAPRE2 TGFB2 SRF PRCP KANK1 JUN NOTCH1 ETS1 MAP4K4 RHOJ PRKCE PPM1F PLCG2 EPPK1 TGFB1 MIR23A TGFB1I1 MIA3 CLASP2 MACF1 CCR6 FGF2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 SP100 EPHA2 GLUL KIT EDN1 PTEN FGFR1 NRP2	down	***
GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.0000207	0.0011554	0.5756103	-0.3640279	-1.862775	135	ANGPT4 SASH1 HMOX1 TEK GLIPR2 GATA2 BMPR2 FGF10 MIR27B TGFBR2 ANXA1 MIR146A HBEGF ADAM17 HSPB1 FOXP1 GATA3 NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 THBS1 PIK3C2A NUS1 ANXA3 MAPRE2 TGFB2 JUN ETS1 MAP4K4 RHOJ PRKCE PPM1F PLCG2 TGFB1 MIR23A CLASP2 CCR6 FGF2 EPB41L5 RTN4 IQSEC1 EDN1 FGFR1 NRP2 FLT4 CTSH HAS2 CALR WNT5A HMGB1 ATOH8 DOCK5 SIRT1 PTGS2 SEMA5A CAPN7	down	**
GO_LUNG_GROWTH	0.0018996	0.0340850	0.4550599	-0.7911271	-1.862070	7	FGF10 SPRY2 TMEM38B MIR17HG	down	*
GO_HEART_GROWTH	0.0000977	0.0037941	0.5384341	-0.4015303	-1.861257	78	RBP4 CCM2L S1PR1 PRKAR1A TGFBR3 TGFBR2 HEG1 TBX2 FOXC2 MIR24-2 TBX5 MIR17HG TGFB2 RBPJ NOTCH1 ADRA1A SAV1 MIR23A PIM1 MEIS1 GATA6 RGS2 RXRA FGF2 PDLIM5 ACACB EDN1 PTEN FGFR1 MIR548C ZFPM2 DUSP6 MAPK1 NOG	down	**
GO_INTERLEUKIN_1_BETA_PRODUCTION	0.0002018	0.0067503	0.5188481	-0.4100691	-1.860731	73	NLRC4 ACP5 IL1B MNDA LPL CD36 CARD16 CD33 CLEC7A HSPB1 FOXP1 SIRPA MEFV CASP1 CCL3 TLR4 CARD8 TYROBP CCR7 MALT1 SUCNR1 SERPINB1 ORM2 MR1 ARRB2 RIPK2 NLRP3 AIM2 EGR1 CX3CR1 TREM2 WNT5A HMGB1	down	**
GO_MOTILE_CILIUM_ASSEMBLY	0.0013127	0.0265525	0.4550599	0.6423566	1.860401	18	MCIDAS MKS1 FOXJ1 DNAAF3 CCDC40 LRRC6 CENPJ BBS5	up	*
GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION	0.0026547	0.0430437	0.4317077	-0.5308134	-1.860145	25	IL1B GATA3 IL18R1 TRAF6 SMAD7 IL6 MALT1 TBX21 CD81 IL18 NLRP3	down	*
GO_POSITIVE_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0027420	0.0439063	0.4317077	-0.5395622	-1.859240	23	HMOX1 GATA2 MIR27B ANXA1 MIR146A AKT3 FOXC2 PIK3C2A RHOJ MIR23A FGF2	down	*
GO_SYNAPTONEMAL_STRUCTURE	0.0010703	0.0230770	0.4550599	0.6016118	1.856798	22	BRCA1 PLK1 STAG3 REC8 SYCP2 HORMAD1 BLM INCENP	up	*
GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.0005654	0.0149604	0.4772708	-0.4378714	-1.856129	51	CD55 TGFBR2 IL23A ANXA1 HLX GATA3 SOCS5 SMAD7 NCKAP1L CD80 CD160 CD83 MALT1 RC3H1 TBX21 RUNX3 CD86 CD81 IL18 RIPK2 NLRP3	down	*
GO_CELLULAR_DEFENSE_RESPONSE	0.0016793	0.0315035	0.4550599	-0.4657951	-1.855006	38	SPN MNDA FOSL1 C5AR1 NCF2 LY96 PRF1 CD300C TYROBP KLRC2 CCR6 CCR9 ADORA2A CX3CR1 ITGB1 NCF1 BCL10 TRAT1 KLRG1 ITK LSP1 CCR5 VEZF1 LGALS3BP	down	*
GO_CALCITONIN_FAMILY_RECEPTOR_ACTIVITY	0.0013928	0.0275668	0.4550599	-0.8713407	-1.854538	5	RAMP3 RAMP2 CALCRL	down	*
GO_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION	0.0014147	0.0278854	0.4550599	-0.8710627	-1.853946	5	ENG TGFBR2 TGFB2	down	*
GO_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE	0.0007762	0.0185075	0.4772708	0.5668714	1.853125	29	NEK2 CCNB1 NDC80 RACGAP1 NUF2 AURKB ECT2 CDT1 BOD1 KIF2C MAD1L1 KNSTRN SPAG5	up	*
GO_CELL_SUBSTRATE_JUNCTION	0.0000000	0.0000002	0.8012156	-0.3194312	-1.852330	367	SLC6A4 LIMS2 ARHGAP31 TEK TSPAN4 DLC1 CAT LPXN RDX ENG CD44 CAV1 CORO1C CDH13 CDC42 NEDD9 IL1RL1 CD9 CBL HSPG2 RHOA NUMB ANXA1 ADAM17 CSRP1 ITGA5 HSPB1 PARVG ANXA5 CAV2 LCP1 TNS1 LAMTOR3 ARHGEF2 CNN1 SORBS3 EPB41L2 RHOB PTPN12 AHNAK SDCBP SORBS1 LIMS1 PLAUR KLF11 DAB2 PARVB VASP PTPRC VIM ACTR3 PEAK1 ADD1 MAPRE2 ACTR2 HCK PROCR FAM107A FLT1 SYNPO2 SNAP23 PDCD6IP LIMD1 RAC2 MAP4K4 HSPA1B RHOG RPL9 JAK1 FERMT2 CAP1 YWHAZ ITGA11 MCAM CD151 SPRY4 RRAS EPPK1 FLNC MME TGFB1I1 PDLIM1 ATP6V0C CD81 CLASP2 GNA13 ACTN2 ADAM10 ICAM1 ARPC2 EPB41L5 XIRP1 DCTN4 DIXDC1 ARL14EP HSPA8 ACTB HNRNPK EPHA2 RPS13 PARVA ARPC5 IQGAP1 CNN2 RSU1 EHD3 PPP1CB IRF2 CYBA CHP1 SVIL MAPK1 ITGB1 ZYX EFNB2 YWHAB CALR SLC9A3R2 BSG LMO7 PPFIA1	down	***
GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION	0.0000208	0.0011554	0.5756103	0.4318536	1.850922	117	PKHD1 MCIDAS CEP72 SPICE1 MDM1 NEK2 BRCA1 BRSK1 STIL PLK1 XRCC2 CCNF HAUS5 RANBP1 CEP250 WDR62 KIF3B AURKA ODF2 POC1A KIF11 CHEK1 C2CD3 CCDC78 CDK1 CROCC CENPJ KIAA0753 SSX2IP CEP63 CEP192 TRIM37 SASS6 CKAP5 CHMP4C CDK5RAP2 HAUS6 HAUS4 CEP152 NUP62 CEP85 ALMS1 CHMP1A MARK4 CHMP2A CHD3 BCAS3 GOLGA2 MAP9 CLASP1	up	**
GO_PHOTOPERIODISM	0.0031859	0.0485812	0.4317077	-0.5458593	-1.849369	22	SIK1 CRY2 RBM4 PER3 USP2 FBXL3 PER2 ID2 PER1	down	*
GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY_PLUS_END_DIRECTED	0.0005988	0.0154183	0.4772708	0.5620820	1.848933	30	KIF1A KIF18B KIF14 DYNC1I1 DNAI1 KIF3B WDR78 KIF11 WDR60 KIF5A KIF19 DYNLL2 KIF20B WDR34 DNAI2	up	*
GO_HISTONE_EXCHANGE	0.0013162	0.0265704	0.4550599	0.5371830	1.847262	36	HJURP RUVBL1 CENPA MIS18A CENPL CENPW ZNHIT1 CENPO CENPH VPS72 CENPP CENPQ ANP32E CHD5 CENPK CENPM CENPT	up	*
GO_REGULATION_OF_LIPID_STORAGE	0.0026172	0.0425047	0.4317077	-0.4683889	-1.846685	37	ABHD5 OSBPL11 PPARG PLA2G10 LPL CD36 MIR146A ABCG1 MSR1 NFKB1 IL6 PNPLA2 EHD1 ACACB SREBF2 NFKBIA	down	*
GO_HUMORAL_IMMUNE_RESPONSE_MEDIATED_BY_CIRCULATING_IMMUNOGLOBULIN	0.0000814	0.0032861	0.5384341	0.4552365	1.846410	84	IGHV4-61 IGHV4-4 IGLV3-27 IGKV1-17 IGKV3-15 IGKV1-16 ZP3 FCER2 IGKV4-1 IGLC7 IGKV2D-28 EXO1 FOXJ1 IGLV1-44 C6 C1RL IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGHG1 IGLV7-43 SUSD4 IGLV6-57 IGHM IGLV1-47	up	**
GO_MITOTIC_SPINDLE	0.0000380	0.0018251	0.5573322	0.4405982	1.844436	99	PKHD1 KIF18B RACGAP1 ASPM AURKB ECT2 ESPL1 TPX2 TFDP2 KIF23 MAP10 AURKA TPR MAD1L1 DCDC2 KIF11 GPSM2 YEATS2 MAD2L1 CKAP2L KNSTRN NUSAP1 IQCB1 CDK1 SPAG5 KLHL22 RANGAP1 TACC3 KIF22 PKP4 KIF20B CDC7 TADA3 AAAS EFHC1 CDK5RAP2 FAM161A NUP62 AGBL5 CTTN CENPE GOLGA2 DCDC1 MAP9	up	**
GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ENDOPLASMIC_RETICULUM	0.0001437	0.0051107	0.5188481	0.4600081	1.842586	78	RACGAP1 COPB2 GOLPH3L GOLPH3 KIF23 KIF15 COPG2 COPG1 KIF3B KIF2C KIF11 KDELR2 KIF3C TMED3 NSF KIF5A PICK1 STX18 KIF2A RAB6B TAPBP ATP9A COG7 KIF22 ARF5 COG4 KLC2 KDELR3 GBF1 ERGIC3 COPZ1 ARFGAP1 RER1 COPA ERGIC1 TMED9 CENPE COPZ2	up	**
GO_NUCLEAR_REPLICATION_FORK	0.0008853	0.0203444	0.4772708	0.5310448	1.842170	38	CDC45 MCM10 TIMELESS PRIM2 GINS4 POLA2 POLD2 SMARCAL1 MMS22L WDHD1 HELB MCM3 ZMIZ2 GINS2 POLD1 RPA1 ZRANB3 PRIM1 TONSL PRPF19 ETAA1 TIPIN POLD3 CDC5L	up	*
GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.0000000	0.0000000	0.9325952	-0.3075462	-1.841826	578	SIRPB1 SLPI FOXF1 HMOX1 SWAP70 FCN1 OLR1 PECAM1 HVCN1 CD55 GAPT GATA2 SPN MNDA LTA4H CAT RAB44 CLEC12A PTPRB OSCAR CD44 PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA CD1C VAPA FUCA1 LAMP1 CBL SLC11A1 LILRB3 IL23A FGR RHOA DNASE1L3 CD36 ANXA1 SLC44A2 CLCF1 DNAJC3 MAN2B1 ADA CD33 ARSB ASAH1 RAP1A GM2A FOXP1 ANPEP PTX3 HLX LCP1 IFNK STOM LAIR1 GATA3 SIRPA IL18R1 CD93 GRN LAMTOR3 TFRC RAB14 CD58 CST3 IL10 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D SOCS5 CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE TLR4 ARHGAP9 CD53 FCER1G SMAD7 GCA DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP CD80 IL6 CTSS PSEN1 SNAP23 VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG PTGER4 ENPP4 GLIPR1 GMFG PRKCE GPR183 MALT1 RC3H1 SERPINB6 CAP1 SUCNR1 TBX21 ZNF683 PLCG2 TNFSF13 PSMD12 ALDH3B1 TREX1 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 TGFB1 AP1G1 DOK3 MILR1 SERPINB1 FPR2 TSPAN14 CD86 DYNC1LI1 ATP6V0C GPR84 CD81 LGALS3 ORM2 BRI3 MFNG PLEKHO2 ADAM10 IST1 COMMD9 UNC13D CCR6 ICAM1 IL18 LAT NBN SEMA4A HSP90AA1 RIPK2 NLRP3 HSPA8 HAVCR2 METTL7A CD19 NHLRC3 KIT SIGLEC9 CTSC DOCK10 ARPC5 SNAP29 P2RX1 RORA PSMD6 IQGAP1 CREG1	down	***
GO_KERATINIZATION	0.0006088	0.0155416	0.4772708	0.5081009	1.837434	47	PCSK6 LIPM KRT5 PKP2 PKP1 ABCA12 KRT16 KRT15 HRNR FLG TGM1 PERP KRT18 CDH3 TMEM79 ST14 PKP3 PKP4 KRT19 PPHLN1 KRT8 SPINK5 KRTAP5-9 PRSS8	up	*
GO_SMOOTH_MUSCLE_CELL_DIFFERENTIATION	0.0008355	0.0195671	0.4772708	-0.4301528	-1.837193	54	EREG FOXF1 EDNRB WNT4 RAMP2 ENG FGF10 NFATC3 TMEM204 ZEB1 NPNT HES1 PIAS1 SRF MED28 NOTCH1 EPC1 SOD2 MYOCD GATA6	down	*
GO_3_5_DNA_HELICASE_ACTIVITY	0.0011906	0.0246731	0.4550599	0.6852098	1.836417	14	CDC45 GINS1 MCM2 GINS4 MCM7 BLM RECQL4 GINS2 MCM6 MCM5	up	*
GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME	0.0018399	0.0335963	0.4550599	0.6037360	1.834406	21	NABP2 CCT6A CCT2 RUVBL2 CCT5 ATR PIH1D1 CCT3 LRWD1 CCT7	up	*
GO_MOTILE_CILIUM	0.0000417	0.0019843	0.5573322	0.4294338	1.833602	115	KLC3 CEP89 DNAH2 PMFBP1 SORD SPAG17 IFT27 AK8 RSPH1 SPAG16 TSGA10 IQCD ODF2 HAVCR1 TEKT2 WDR66 NME5 SLC9A3R1 IFT172 GAS8 DNAH11 DRC1 SPAG6 KIF2A AK7 DNAH5 TCTE1 IFT52 CATSPERG SPEF1 CATSPER3 NPHP1 EFCAB2 MNS1 IQCG TEKT3 SPA17 DNAJB13 IQUB ROPN1B CATSPER2 DNAI2 DYNC2H1 RSPH4A SPAG4 CATSPER1 CCDC181 DNAH1 ENKUR TACR1 ADAM15 TSSK4	up	**
GO_ENDOCARDIAL_CUSHION_DEVELOPMENT	0.0024458	0.0403154	0.4317077	-0.4551363	-1.831911	39	TMEM100 ACVRL1 FOXF1 BMP2 ENG BMPR2 TGFBR2 TBX2 SNAI1 TBX5 DCHS1 TGFB2 RBPJ NOTCH1	down	*
GO_NEGATIVE_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS	0.0031179	0.0477299	0.4317077	-0.5285183	-1.831414	24	ACP5 FYN CAV1 RHOA SIRPA IL10 ROCK2 PTGIS CD34 MPV17L TSPO	down	*
GO_RETINA_HOMEOSTASIS	0.0008571	0.0197861	0.4772708	0.5085444	1.831393	45	LTF TF MDM1 ZG16B PROM1 CIB2 BBS1 CNGB1 IQCB1 CROCC CDH3 POC1B LCA5 ABCA4	up	*
GO_HIGH_DENSITY_LIPOPROTEIN_PARTICLE	0.0020263	0.0353681	0.4317077	0.7000168	1.830532	13	SAA1 SAA2 CETP APOL1 PLTP HPR PON1 LIPC HDLBP	up	*
GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION	0.0025793	0.0420217	0.4317077	-0.6041186	-1.830360	16	ANXA1 MIR146A CD33 IL10 ARRB1 KLF4	down	*
GO_OUTFLOW_TRACT_MORPHOGENESIS	0.0004112	0.0116081	0.4984931	-0.4093627	-1.829792	68	SMAD6 SOX18 TBX3 ENG FOLR1 SOX17 CITED2 BMPR2 TGFBR3 TGFBR2 TBX2 FOXC2 CLDN5 SEC24B HES1 MIR17HG TGFB2 RBPJ JUN NOTCH1	down	*
GO_HISTONE_SERINE_PHOSPHORYLATION	0.0016818	0.0315035	0.4550599	0.7261855	1.829283	11	HMGA2 CCNB1 AURKB AURKA PRKAA2	up	*
GO_MEMBRANE_REGION	0.0000000	0.0000046	0.7337620	-0.3254154	-1.828738	275	SLC6A4 TNR AKAP5 HMOX1 TEK OLR1 DLC1 EDNRB PECAM1 ADTRP CD55 EMP2 FYN CAV1 CORO1C MYADM CDH13 BMPR2 ADCYAP1R1 S1PR1 PRKAR1A MAL CBL TGFBR2 RFTN1 SCN5A CD8A CD36 ATP2B1 ADAM17 ABCG2 MALL CAV2 PAG1 MS4A1 STOM LAMTOR3 CRK SGCA LRP4 PPT1 AHNAK KCNMA1 BIRC2 SDCBP SORBS1 CTSD PTPRC HPSE ARC UNC5A PTGIS GNAI2 BACE1 ADD1 PI4K2A HCK KCNA5 MYO1C PPP2CA ADCY2 PSEN1 PIKFYVE CD48 ADRA1A	down	***
GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	0.0001363	0.0049434	0.5188481	-0.3928778	-1.825311	79	CD55 TGFBR2 IL23A RHOA ANXA1 ADA HLX GATA3 MAPK8IP1 SOCS5 PTPRC SMAD7 NCKAP1L CD80 CD160 CD83 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 CD81 IL18 RIPK2 NLRP3 ADORA2A ZBTB16 HMGB1 CD3E IRF1 RC3H2 IRF4 NFKBIZ EBI3 CBFB PNP	down	**
GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY	0.0000000	0.0000000	0.8513391	-0.3118880	-1.824780	453	SIRPB1 SLPI FOXF1 HMOX1 FCN1 OLR1 ACE PECAM1 HVCN1 CD55 GATA2 MNDA LTA4H CAT RAB44 CLEC12A PTPRB OSCAR CD44 PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA VAPA FUCA1 LAMP1 CBL SLC11A1 LILRB3 FGR RHOA DNASE1L3 CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ADAM17 ASAH1 RAP1A GM2A ANPEP PTX3 SERPINB9 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 RAB14 CD58 CST3 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE ARHGAP9 CD53 FCER1G GCA DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP IL6 CTSS PSEN1 SNAP23 VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG ENPP4 GLIPR1 GMFG SERPINB6 CAP1 PSMD12 ALDH3B1 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 DOK3 MILR1 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ORM2 BRI3 PLEKHO2 ADAM10 IST1 COMMD9 UNC13D LAT WDR1 HSP90AA1 HSPA8 METTL7A NHLRC3 KIT SIGLEC9 CTSC ARPC5 SNAP29 P2RX1 PSMD6 IQGAP1 CREG1 CNN2 ANO6 LYZ CYBA ATP6V0A1 CTSH TMEM30A ATP11B MAPK1 ITGAL FTL S100A8 RAB37 FPR1 KMT2E NFAM1 PIK3CG QSOX1	down	***
GO_SPLICEOSOMAL_SNRNP_ASSEMBLY	0.0018114	0.0332048	0.4550599	0.5304933	1.824258	36	COIL GEMIN7 GEMIN4 PRPF6 SNRPE GEMIN5 PRMT7 GEMIN6 CD2BP2 SNRPD1 LSM4 PRMT5 SNRPD2 WDR77 PRPF31 SNUPN PRPF3 SNRPC SART1 SART3 GEMIN2 CLNS1A PRPF19	up	*
GO_NEURON_FATE_SPECIFICATION	0.0017695	0.0327237	0.4550599	0.7240928	1.824011	11	MNX1 EYA1 SIX1 FOXA1 ESRP1	up	*
GO_MEMBRANE_REPOLARIZATION_DURING_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.0006449	0.0161761	0.4772708	0.7096978	1.823931	12	KCNJ8 KCNH2 NOS1AP DLG1 KCNE3 RNF207	up	*
GO_TERTIARY_GRANULE	0.0000248	0.0013295	0.5756103	-0.3608815	-1.822227	129	OLR1 CD55 LTA4H CLEC12A PTPRB OSCAR CHIT1 YPEL5 LAMP1 SLC11A1 RHOA CD33 ASAH1 PTX3 STOM LAIR1 SIRPA CD93 LAMTOR3 RAB14 CD58 CST3 PTAFR GAA CTSD ITGAX CD53 FCER1G HGSNAT NCKAP1L PRCP CTSS SNAP23 ATP11A STX7 ENPP4 SERPINB6 CR1 TIMP2 STXBP3 SIGLEC14 DOK3 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ADAM10	down	**
GO_NUCLEOSOME_ORGANIZATION	0.0001171	0.0043804	0.5384341	0.4458712	1.821044	87	HJURP RUVBL1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A SMARCD3 SMARCC1 CHAF1A CENPL CENPW CHAF1B ZNHIT1 CENPO ASF1B CENPH VPS72 CENPP HIRA CENPQ ANP32E CHD5 CENPK SUPT16H CENPM HMGA1 CENPT NFE2 SMARCC2 SMARCA4	up	**
GO_MITOCHONDRIAL_TRANSLATIONAL_TERMINATION	0.0001498	0.0052536	0.5188481	0.4505913	1.820834	83	MRPL46 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 MRPS30 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 GADD45GIP1 MRPL9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 MRPS16 MRPL12 MRPL43 MRPL2 MRPS6	up	**
GO_EXTRACELLULAR_TRANSPORT	0.0019474	0.0346415	0.4550599	0.5710560	1.820411	25	STK36 SPAG17 KIF27 DPCD NME5 GAS8 DNAH11 CCDC40 KIAA0556 LRRC6 DNAH5 SPA17 DNAH1 ARRDC1 DNAAF1 ROPN1L	up	*
GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS	0.0000006	0.0000591	0.6594444	-0.3437543	-1.819360	189	CXCL3 KMO IL1A SASH1 EDNRB SCIMP CD55 IL1B LY86 MYD88 TBXA2R IL1RN TRIB1 RHOA TXNIP CD36 MIR146A CARD16 PPP1R15B CLEC7A TNIP3 LITAF SIRPA TRAF6 PDE4D IL10 CASP1 PTAFR LY96 CCL3 NFKB1 CXCL2 IRAK2 VIM AXL TLR4 ZMPSTE24 WFS1 IL24 HCK CD80 IL6 CARD8 IRF8 PRKCE MALT1 CXCL5 MAPK8 TGFB1 CD6 CD86 PLSCR4 KLRC4-KLRK1 PLAA PDE4B TSPO ICAM1 IL18 TFPI RIPK2 NLRP3 HAVCR2 NFKBIA KLRK1 CSF2 SERPINE1 CX3CR1 MAPK1 TREM2 ZFP36 WNT5A SHPK BCL10 CTR9 HMGB1	down	***
GO_DYNEIN_COMPLEX	0.0006928	0.0172076	0.4772708	0.5028321	1.818380	47	DNAH2 NUDCD3 DNAH3 DYNC1I1 DNAH14 DCTN2 DNAI1 TPR WDR78 CCDC114 WDR60 DNAH8 DNAH11 DRC1 DNAH6 SNX4 DYNLL2 DNAH5 DNAH7 WDR34 DYNC1LI2 DNAI2 DYNC2H1 DNAH1 DNAL4 DYNC1H1 WDR63 DYNLT1 CCDC65 DNAH9 DNAL1 DNAH12 TCTEX1D2 DNAH10	up	*
GO_DNA_RECOMBINATION	0.0000014	0.0001233	0.6435518	0.3912178	1.816057	223	TRIP13 RUVBL1 CDC45 PARPBP TIMELESS POLQ PAGR1 MND1 PIF1 BRCA1 NABP2 FIGNL1 RBBP8 MCM4 MCM2 RAD54B XRCC2 MCM8 LIG3 GINS4 MAGEF1 RUVBL2 EXO1 TP53BP1 POLM RHNO1 AUNIP TOP2A EME1 REC8 MCM7 MMS22L PRKDC HELB RAD54L MCM3 EME2 CHEK1 ACTL6A RAD51AP1 XRCC1 THAP10 BRIP1 BLM ERCC2 RECQL5 PARP1 POLN RFWD3 UNG AP5Z1 FEN1 MAD2L2 RECQL4 TEP1 DCLRE1C POLL RAD51D GINS2 POLB ATAD5 SLX4 CDC7 RAD50 ANKRD31 KLHDC3 UBQLN4 PGBD5 PALB2 RPA1 FANCM MCM6 XRCC4 MCM5 ZRANB3 IGHMBP2 MSH4 MCRS1 MSH2 NFRKB RTEL1 STAT6 INO80E RAD51 PAXIP1 SIRT6 TONSL BCL6 TCF3 SWI5	up	***
GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION	0.0017634	0.0326794	0.4550599	0.5752862	1.814564	24	PARPBP POLQ MAGEF1 TP53BP1 HELB BLM RECQL5 MAD2L2 UBQLN4 ZRANB3 MSH2 RTEL1 BCL6 MSH6 RMI2 MSH3	up	*
GO_LIPID_STORAGE	0.0007183	0.0177101	0.4772708	-0.4189146	-1.812880	59	ABHD5 OSBPL11 PPARG IL1B PLA2G10 LPL CAV1 CD36 MIR146A STARD4 GM2A ABCG1 MSR1 NFKB1 HEXB IL6 PNPLA2 EHD1 CRY1 ACACB SOAT1 SREBF2 NFKBIA	down	*
GO_METAPHASE_PLATE_CONGRESSION	0.0003267	0.0096599	0.4984931	0.4910634	1.812253	53	SPICE1 CCNB1 CENPF NDC80 KIF14 NUF2 CDCA8 CDT1 SPDL1 BOD1 KIF2C MAD1L1 CDCA5 PSRC1 SPAG5 TRAPPC12 KPNB1 CDC23 KIF22 CENPQ CHMP4C NUP62 CHMP1A CHMP2A CENPE RRS1 CHMP6 DYNC1H1	up	**
GO_REGULATION_OF_LYMPHOCYTE_MIGRATION	0.0007338	0.0179186	0.4772708	-0.4216966	-1.811642	53	GCSAML ADTRP SPN RHOA APOD ADAM17 CRK CCL3 CCL4 JAM2 XCL2 OXSR1 LRCH1 DOCK8 MIA3 KLRC4-KLRK1 ADAM10 CCL20 CCR6	down	*
GO_MICROTUBULE_BASED_PROCESS	0.0000000	0.0000000	0.8870750	0.3603444	1.809799	632	KIF1A PKHD1 KIF12 MCIDAS KLC3 CEP72 SPICE1 KIF20A MDM1 DNAH2 AP3B2 CHEK2 NEK2 CCNB1 UCHL1 KIF18B NDC80 BRCA1 STK36 TUBB2B TTK RACGAP1 BRSK1 GTSE1 IFT122 KIF14 SPAG17 ASPM STIL MSTO1 TTC26 CEP70 PLK1 NUF2 IFT27 AURKB CENPA ESPL1 TPX2 GAPDH FIGNL1 MYBL2 DNAH3 PRC1 EFNA5 XRCC2 CCNF DYNC1I1 CIB1 KIF27 DNAH14 DCTN2 SPDL1 DNAI1 HAUS5 RANBP1 CEP250 WDR62 RSPH1 ARMC4 DLG1 MAP7 KIF23 CUL9 SPAG16 CUL7 BICD1 KIF15 COPG2 COPG1 KIF3B CCDC13 AUNIP MAP10 AURKA ODF2 IFT43 TPR KIF2C CENPW POC1A HYDIN WDR78 DPCD TEKT2 FSD1 HOOK1 CCDC114 WDR73 KIF11 GPSM2 BLOC1S1 WDR66 WDR60 NME5 DNAH8 CHEK1 IFT172 MAD2L1 GAS8 KIF3C CLIP3 DNAAF3 DNAH11 C2CD3 TRPV4 SPRY1 PARD3 CCDC40 PSRC1 MARK1 CCDC78 KNSTRN DRC1 NUSAP1 PAK1 KIAA0556 LRGUK LRRC6 CDK1 CROCC DNAH6 CEP97 KIF5A CENPJ BIRC5 AP3D1 KIAA0753 SUN1 KIF19 KIF2A KIF7 SSX2IP CCDC88C DYNLL2 SPAG5 SAPCD2 LCA5 DNAH5 PRKAA2 FGFR1OP IFT52 KPNB1 VBP1 CEP63 SPEF1 CEP192 TUBG1 DLGAP5 SPG7 DNAH7 NINL TACC3 LLGL2 CCDC151 TUBB2A TUBA3D KIF22 IQCG TRIM37 TUBA8 KIF21A SPAG1 MAP6D1 KIF20B TEKT3 SPA17 TRAF3IP1 DNAJB13 KLC2 SASS6 CKAP5 CDC20 WDR34 TUBG2 AAAS TTLL3 EFHC1 AP3M2 CHMP4C CDK5RAP2 DYNC1LI2 KIF21B CKAP2 DNAI2 WDR35 HAUS6 DYNC2H1 STMN3 KATNB1 SKAP1 TTLL6 RCC1 HAUS4 RSPH4A NEFH CEP152 CNTN2 NUP62 CEP85 CATSPER1 ALMS1 APC2 ULK4 NTMT1 NAV1 TUBGCP4 SYBU ICK CLUAP1 DNAH1 HOOK2 TUBA4B CCDC88B CHMP1A MARK4 TRAK1 CHMP2A CHD3 CDK5 LLGL1 RHOT2 CELSR2 ERBB2 BCAS3 MAPK8IP3 CAMSAP3 CENPE DTNBP1	up	***
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	0.0000001	0.0000110	0.7049757	-0.3166266	-1.809428	299	TNR FFAR4 SIGLEC11 SEMA6B AJAP1 SEMA3G GPR17 SEMA6A ACP5 FOXF1 TEK PPARG ADTRP WFDC1 WNT4 THBD CDH5 SAMHD1 CLEC12B CALCRL HMGCR CD9 TRIB1 APOD SEMA6D MIR146A MYOZ1 SH2B3 CARD16 SEMA3B ADA ANXA5 RNF125 SERPINB9 GATA3 SIRPA RB1 GRN CRK WNT3A KANK2 PDGFA IL10 DUSP3 PTPRO MEFV KLF4 PLAUR THBS1 SOCS5 NFKB1 CDKN1A NR1D2 PTPRC DUSP1 UBASH3B PTGIS BACE1 KREMEN1 SOCS3 SEC14L1 PSMA1 NOTCH1 ETS1 CARD8 PTGER4 RTN4R CST7 CD34 YTHDF3 EPPK1 TREX1 CR1 SMPDL3B FPR2 YTHDF2 NLRP6 CNOT7 KLRC4-KLRK1 CLASP2 GPR18 SYT11 FGF2 TFPI ARRB2 SEMA4A EPHA4 NLRP3 HAVCR2 GRIN3A ADORA2A EDN1 KLRK1 PTEN PRKG1 RORA ITCH LDLR	down	***
GO_CHROMATIN_REMODELING	0.0000270	0.0014195	0.5756103	0.4146624	1.808978	129	HMGA2 TP63 HELLS HJURP RUVBL1 CENPA SOX9 MIS18A RUVBL2 SMARCD3 SMARCC1 FOXA1 CENPL CBX3 TPR CENPW MORC2 ZNHIT1 ACTL6A CENPO PIH1D1 TADA2A PAK1 CENPH NPM3 VPS72 CENPP PABPC1L SATB2 CENPQ HDAC1 ANP32E CHD5 ESR1 CENPK BAZ2A CENPV CENPM HMGA1 KDM4B CENPT SMARCC2 SUV39H2 SMARCA4 INO80E CHD3 SIRT6 SRCAP KDM5B SMARCB1 ACTR5	up	**
GO_SPINDLE_ELONGATION	0.0013460	0.0269036	0.4550599	0.8000112	1.808644	8	RACGAP1 AURKB PRC1 KIF23 MAP10	up	*
GO_CYTOKINE_METABOLIC_PROCESS	0.0001197	0.0044437	0.5384341	-0.3791313	-1.805547	92	EREG IL1A HMOX1 SPN IL1B TNFRSF8 CLEC7A HSPB1 GATA3 TRAF6 IL10 MAP2K3 PTAFR KLF4 TNFSF15 THBS1 NFKB1 PTPRC TLR4 SFTPD INHBA CD80 IL6 PSEN1 TYROBP	down	**
GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN	0.0000001	0.0000179	0.6901325	-0.3204428	-1.803818	272	SMAD6 CXCL3 SLPI ACP5 KMO IL1A SASH1 EDNRB SCIMP CD55 IL1B THBD LY86 MYD88 TBXA2R C5AR1 FGF10 IL1RN SLC11A1 TRIB1 CASP9 RHOA CD36 MIR146A CARD16 ADAM17 TNIP3 LITAF FOXP1 SIRPA TRAF6 PDE4D IL10 PTGIR CASP1 PTAFR LY96 CCL3 NFKB1 CXCL2 IRAK2 VIM SELP AXL TLR4 IL24 GNRH1 HCK CD80 IL6 JUN NOTCH1 CARD8 JUNB PTGER4 CCR7 IRF8 PRKCE PTGER2 MALT1 CXCL5 PLCG2 FOS PELI1 MAPK8 IRF5 TGFB1 AKIRIN2 CD6 IFNAR1 CD86 PLSCR4 KLRC4-KLRK1 PLAA PDE4B TSPO JUND ICAM1 IL18 TFPI TAB2 RIPK2 NLRP3 HAVCR2 NFKBIA EDN1 KLRK1 CSF2 CSF2RB SERPINE1 CNR2 CX3CR1 MAPK1 TREM2 S100A8 ZFP36 WNT5A SSC5D SHPK BCL10 CTR9 AKAP12 HMGB1	down	***
GO_NON_RECOMBINATIONAL_REPAIR	0.0005357	0.0144102	0.4772708	0.4741997	1.801750	61	HMGA2 POLQ BRCA1 RBBP8 LIG3 TP53BP1 POLM AUNIP PRKDC XRCC1 MAD2L2 DCLRE1C POLL POLB PARP9 SLX4 RAD50 UBE2V2 XRCC4 UIMC1 DTX3L PAXIP1 NUDT16L1 PIAS4 PRPF19 RNF8 DCLRE1B DCLRE1A HERC2 XRCC5 XRCC6 BARD1 REXO4 ERCC8	up	*
GO_REGULATION_OF_MEMBRANE_REPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.0005958	0.0154035	0.4772708	0.8633112	1.801695	6	NOS1AP DLG1 KCNE3 RNF207	up	*
GO_AMEBOIDAL_TYPE_CELL_MIGRATION	0.0000000	0.0000070	0.7195128	-0.3096047	-1.801201	345	ANGPT4 SEMA6B SEMA3G SEMA6A ACVRL1 SASH1 HMOX1 SOX18 TEK EDNRB PECAM1 PPARG ADTRP GLIPR2 GATA2 EMP2 BMPER FOLR1 SOX17 BAG4 CORO1C CDH13 BMPR2 TBXA2R FGF10 MIR27B TGFBR2 RHOA ZEB2 SEMA6D ANXA1 MIR146A MMRN2 PTPRM SEMA3B HBEGF ARSB ADAM17 CLEC14A HSPB1 FOXP1 ADIPOR1 GATA3 NR4A1 RGCC NFE2L2 TNS1 GRN AKT3 KANK2 FOXC2 NODAL RHOB MAP2K3 ROCK2 STAT5A AMOTL1 TNFSF12 KLF4 ZFAND5 THBS1 ADAMTS9 MIR24-2 PIK3C2A PAFAH1B1 NUS1 ANXA3 MAPRE2 ARHGDIB TGFB2 SRF PRCP KANK1 SLC8A1 WASF2 APPL1 JUN NOTCH1 ETS1 MAP4K4 RHOJ PRKCE CAP1 PPM1F PLCG2 EPPK1 WNT11 TGFB1 MIR23A CYGB TGFB1I1 MIA3 CLASP2 MACF1 CCR6 FGF2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 SP100 EPHA2 GLUL RET KIT EDN1 PTEN FGFR1 NRP2	down	***
GO_NUCLEAR_CHROMOSOME_TELOMERIC_REGION	0.0003471	0.0101654	0.4984931	0.4371122	1.798196	91	THOC3 PIF1 NABP2 MCM4 MCM2 ORC1 TP53BP1 CBX3 ATR MCM7 PRKDC MCM3 XRCC1 PML PARP1 CBX5 CDK1 DNA2 FEN1 CBX1 TELO2 DCLRE1C RAD51D POLD1 SLX4 RAD50 RPA1 MCM6 THOC5 WRNIP1 MCM5 MSH2 RAD51 SIRT6 APEX1 NAT10 NHP2 DCLRE1B DCLRE1A POT1 XRCC5 CTC1 ORC5 MEN1 XRCC6	up	*
GO_CENTRIOLE_CENTRIOLE_COHESION	0.0010032	0.0222463	0.4550599	0.6994808	1.797673	12	NEK2 CEP250 ODF2 CROCC	up	*
GO_BICARBONATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.0022646	0.0383137	0.4317077	0.6298720	1.797280	17	SLC26A4 SLC26A8 SLC4A4 SLC4A8 SLC4A11 SLC26A2 SLC4A9 SLC26A1	up	*
GO_INTRACILIARY_TRANSPORT_INVOLVED_IN_CILIUM_ASSEMBLY	0.0023098	0.0388180	0.4317077	0.5225452	1.796172	35	IFT122 TTC26 IFT27 KIF3B IFT43 WDR60 IFT172 KIF3C SSX2IP DYNLL2 IFT52 TRAF3IP1 WDR34 WDR35 DYNC2H1 CLUAP1 TTC30B	up	*
GO_PYRIMIDINE_RIBONUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS	0.0030411	0.0474866	0.4317077	0.7584996	1.794956	9	UMPS CAD UCK2 UCKL1 UPP2 DHODH	up	*
GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.0015686	0.0302342	0.4550599	-0.4714275	-1.794915	33	CD55 TGFBR2 IL23A ANXA1 HLX SOCS5 NCKAP1L CD80 CD160 CD83 MALT1 CD86 CD81 IL18 RIPK2 NLRP3	down	*
GO_POSITIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY	0.0010618	0.0229576	0.4550599	0.6976538	1.792978	12	PAGR1 FOXA1 PPP5C SKP2 PARP1 PAK1	up	*
GO_GLYCOLYTIC_PROCESS_THROUGH_FRUCTOSE_6_PHOSPHATE	0.0027667	0.0441541	0.4317077	0.5896908	1.791730	21	PGM2L1 GPI GAPDH ALDOC PKM PFKP ALDOA ALDOB BPGM FOXK1 HK2 PFKM PGAM1 ENO1	up	*
GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION	0.0011444	0.0241867	0.4550599	-0.4269280	-1.791638	50	CAV1 CALCRL ADRA1D TBXA2R RHOA ATP2B1 ADA ADRB2 SETD3 CNN1 KCNMA1 NPNT TACR2 PTAFR SRF ADRA1A MYOCD RGS2 KIT EDN1 PRKG1 P2RX1 DOCK4 SPHK1	down	*
GO_RECEPTOR_INTERNALIZATION	0.0003723	0.0107502	0.4984931	-0.3801302	-1.791622	84	RAMP3 SFRP4 RAMP2 PCSK9 CAV1 CALCRL CD9 NUMB CD36 PICALM WNT3A TFRC ARRB1 SDCBP ARC FCER1G EPS15 TBC1D5 LRRTM2 MAGI2 RAB31 ACKR3 GRB2 SNX1 GRIA1 PLCG2 MTMR2 CD81 ANKRD13A GRK4 ARRB2 RAB5A	down	*
GO_CHROMOSOME_TELOMERIC_REGION	0.0000830	0.0033119	0.5384341	0.4140887	1.791602	122	CHEK2 THOC3 PIF1 NABP2 MCM4 MCM2 ORC1 TP53BP1 CBX3 ATR MCM7 PRKDC MCM3 CHEK1 XRCC1 BLM PML PARP1 TERC CBX5 CDK1 DNA2 FEN1 EZH2 CBX1 RECQL4 TEP1 TELO2 DCLRE1C RAD51D LRWD1 POLD1 SLX4 RAD50 RPA1 MCM6 THOC5 WRNIP1 MCM5 MSH2 RTEL1 RAD51 SIRT6 APEX1 NAT10 NHP2 RNF8 DCLRE1B DCLRE1A POT1 XRCC5 CTC1 ORC5 MEN1 XRCC6 ZBTB48	up	**
GO_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME	0.0010738	0.0231035	0.4550599	-0.4049443	-1.788740	61	SRSF7 DYRK1A RBM7 TRA2B RBM4 SRSF2 HNRNPU SRSF5 REST SRSF3 CELF1 DDX17 WTAP SMU1 DDX5 MBNL2 CELF2 SRSF6 SRSF4 KHDRBS1 MAGOH MBNL1 SRSF10 THRAP3 SFPQ SAP18	down	*
GO_TRANSLATIONAL_TERMINATION	0.0002485	0.0079946	0.4984931	0.4293563	1.788219	96	MRPL46 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 MRPS30 GLE1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 JMJD4 MRPL4 DAP3 GFM2 CHCHD1 C12orf65 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 N6AMT1 GADD45GIP1 MRPL9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 APEH MRPS16 MRPL12 MRPL43 MRPL2 MRPS6	up	**
GO_MITOTIC_NUCLEAR_ENVELOPE_DISASSEMBLY	0.0011936	0.0246856	0.4550599	0.6951230	1.786474	12	CCNB1 PLK1 CCNB2 PRKCA CDK1 LPIN1	up	*
GO_SMOOTH_MUSCLE_CONTRACTION	0.0003223	0.0096339	0.4984931	-0.3782005	-1.785599	87	EDNRB CAV1 CALCRL ADRA1D TBXA2R RHOA ATP2B1 ADA NMUR1 ADRB2 PDE4D SETD3 CNN1 ROCK2 KCNMA1 NPNT TACR2 PTAFR ROCK1 PTGER3 PIK3C2A RAP1GDS1 MYH11 SRF SLC8A1	down	**
GO_PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS	0.0004880	0.0134035	0.4984931	0.4854533	1.783821	52	GPAT2 TYMS UMPS SMUG1 TAMM41 NME1 NME9 NME5 DCTPP1 CAD UCK2 UNG ENPP3 UCKL1 UPP2 MBD4 DHODH DTYMK AGPAT5 LCLAT1 NT5M	up	*
GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX	0.0022339	0.0379842	0.4317077	0.5462926	1.783001	28	LSM5 PRPF6 SNRPE EFTUD2 SNRPD1 LSM7 LSM4 TXNL4A PRPF18 SNRPD2 TXNL4B USP39 PRPF31 SNRNP200 ZMAT2 PRPF3 SART1 SART3	up	*
GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING	0.0026935	0.0433964	0.4317077	0.5971697	1.782696	20	BRCA1 WDR70 RBBP8 HELB BRIP1 BLM DNA2 SLX4 RAD50 UBE2V2	up	*
GO_INTERLEUKIN_2_PRODUCTION	0.0006060	0.0155087	0.4772708	-0.4101036	-1.782491	58	IL1A IL1B SLC11A1 ANXA1 CLEC7A GATA3 TRAF6 SPTBN1 PDE4D PTPRC SFTPD FCER1G CD80 CD83 MALT1 TBX21 CD34 CD86 PDE4B IL18 RIPK2 HAVCR2 KAT5 ZFP36 CD3E IRF4 CD4 PNP	down	*
GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0013412	0.0268644	0.4550599	0.5526304	1.781959	27	CCNB1 STOX1 CDK4 DBF4B CDC25A DTL SMARCD3 CDC25C CDK1 MTA3 ATAD5 CDC7 WNT10B CDC25B FBXO5 NPM1 RCC2 BRD4	up	*
GO_REGULATION_OF_WOUND_HEALING	0.0000495	0.0022276	0.5573322	-0.3597856	-1.781586	117	AJAP1 ADTRP WFDC1 WNT4 THBD CAV1 TBXA2R HMGCR CD9 TGFBR2 CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 CLEC7A ANXA5 NFE2L2 CRK PDGFA FOXC2 PLAUR THBS1 CDKN1A SELP HPSE TLR4 FCER1G PLEK UBASH3B KANK1 DUOX1 ENPP4 PRKCE CD34 SRSF6 EPPK1 TEC CLASP2 FGF2 TFPI CXCR4 EDN1 PTEN PRKG1 ANO6 SERPINE1 CDKN1B	down	**
GO_ENDOCRINE_PROCESS	0.0010880	0.0233101	0.4550599	-0.4144600	-1.780553	53	RAB11FIP1 ACE TBX3 IL1B HCAR2 RHOA FZD4 GATA3 CES1 TACR2 INHBA RAB8B CTSZ SUCNR1 MME CPA3 CRY1 EDN1 FGFR1 SMAD4 CYBA	down	*
GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION	0.0000000	0.0000005	0.7749390	0.3618089	1.780254	458	PKHD1 MCIDAS CEP72 SPICE1 KIF20A MDM1 CHEK2 NEK2 CCNB1 KIF18B NDC80 BRCA1 TUBB2B TTK RACGAP1 BRSK1 SPAG17 ASPM STIL MSTO1 TTC26 CEP70 PLK1 NUF2 AURKB CENPA ESPL1 TPX2 GAPDH FIGNL1 MYBL2 PRC1 EFNA5 XRCC2 CCNF CIB1 DCTN2 SPDL1 DNAI1 HAUS5 RANBP1 CEP250 WDR62 RSPH1 ARMC4 DLG1 MAP7 KIF23 CUL9 SPAG16 CUL7 BICD1 KIF3B CCDC13 AUNIP MAP10 AURKA ODF2 TPR KIF2C CENPW POC1A HYDIN TEKT2 FSD1 HOOK1 CCDC114 WDR73 KIF11 GPSM2 DNAH8 CHEK1 IFT172 MAD2L1 GAS8 CLIP3 DNAAF3 C2CD3 TRPV4 SPRY1 PARD3 CCDC40 PSRC1 MARK1 CCDC78 KNSTRN DRC1 NUSAP1 PAK1 LRGUK LRRC6 CDK1 CROCC CEP97 CENPJ BIRC5 KIAA0753 SUN1 KIF19 KIF2A SSX2IP CCDC88C SPAG5 SAPCD2 DNAH5 PRKAA2 FGFR1OP KPNB1 CEP63 SPEF1 CEP192 TUBG1 DNAH7 NINL TACC3 LLGL2 CCDC151 TUBB2A IQCG TRIM37 TUBA8 SPAG1 MAP6D1 TRAF3IP1 DNAJB13 SASS6 CKAP5 CDC20 TUBG2 AAAS TTLL3 EFHC1 CHMP4C CDK5RAP2 DYNC1LI2 CKAP2 DNAI2 HAUS6 STMN3 KATNB1 SKAP1 TTLL6 RCC1 HAUS4 RSPH4A NEFH CEP152 CNTN2 NUP62 CEP85 ALMS1 APC2 ULK4 NTMT1 NAV1 TUBGCP4 DNAH1 HOOK2 TUBA4B CCDC88B CHMP1A MARK4 CHMP2A CHD3 CDK5 LLGL1 BCAS3 CAMSAP3 CENPE	up	***
GO_SPECIFIC_GRANULE_MEMBRANE	0.0002943	0.0089700	0.4984931	-0.3840021	-1.780007	78	OLR1 HVCN1 RAB44 CLEC12A PTPRB CD36 SLC44A2 CD33 RAP1A STOM LAIR1 CD93 LAMTOR3 BST1 PLAUR ATP6V1D TMBIM1 CD53 DEGS1 CMTM6 HGSNAT SNAP23 ATP11A ALDH3B1 FPR2 TSPAN14 GPR84 ADAM10 P2RX1 ANO6 CYBA TMEM30A ITGAL RAB37	down	**
GO_NEGATIVE_REGULATION_OF_CELL_MOTILITY	0.0000006	0.0000605	0.6594444	-0.3197333	-1.779025	236	ANGPT4 ACVRL1 HMOX1 DLC1 PPARG ADTRP TIE1 WNT4 ENG CORO1C CITED2 TBXA2R TRIB1 RHOA APOD SEMA6D MIR146A MMRN2 PTPRM MCTP1 ADA ADIPOR1 ABHD6 DACH1 GATA3 RGCC NFE2L2 CRK SFRP1 NODAL RHOB ADARB1 DUSP3 KLF4 THBS1 ADAMTS9 CLDN5 CLIC4 MIR24-2 RECK DUSP1 SMAD7 TBX5 IL24 ARHGDIB STK24 GNRH1 SRF SRGAP2C KANK1 PODN MAGI2 MITF LRCH1 NOTCH1 PTGER4 RRAS FOXO3 EPPK1 CD74 WNT11 TGFB1 CYGB MIA3 KLRC4-KLRK1 MYOCD CLASP2 GPR18 LDLRAD4 FGF2 VASH1 SP100 LIMCH1 SCAI KLRK1 PTEN PRKG1 NRG1 STARD13 ACVR1C GREM1 SERPINE1 C5AR2 CX3CR1 C5 PIP5KL1 NOG MIR640 MIR2355 CALR	down	***
GO_SPINDLE	0.0000004	0.0000422	0.6749629	0.3720797	1.778590	302	PKHD1 DDX11 SPICE1 KIF20A CEP89 BUB1B NEK2 CCNB1 CENPF KIF18B TTK RACGAP1 KIF14 ASPM PLK1 CDCA8 AURKB ECT2 ESPL1 CDC6 TPX2 TFDP2 PRC1 DYNC1I1 SPDL1 HAUS5 WDR62 RSPH1 KIF23 BOD1 KIF15 KNTC1 KIF3B AUNIP FBF1 MAP10 AURKA CBX3 ODF2 TPR SNCG MAD1L1 POC1A TTLL12 NSUN2 DCDC2 WDR73 KIF11 GPSM2 YEATS2 WDR60 TOPBP1 MAD2L1 CKAP2L SPAG8 ERCC2 PSRC1 INCENP KNSTRN NUSAP1 IQCB1 CDK1 DIDO1 BIRC5 KIF2A SPAG5 TTC23L POC1B RAB11FIP4 CBX1 MAD2L2 KLHL22 RANGAP1 MZT2A MZT2B CEP63 TUBG1 DLGAP5 TACC3 KIF22 PKP4 CLTA KIF20B NUP85 CEP128 JTB POLB CDC7 TADA3 CENPV CKAP5 CDC20 TUBG2 AAAS EFHC1 CDK5RAP2 CKAP2 HAUS6 FAM161A KATNB1 HAUS4 NUP62 CEP85 MICAL3 ALMS1 SHCBP1 TUBGCP4 NUBP2 AGBL5 CTTN CENPE E4F1 GOLGA2 CDC25B DCDC1 MAP9 CLASP1 TMEM201 UNC119 DNAAF1 MAK KLHL42 PLK4 FAM110C PRPF19 DSN1 FBXO5 TUBGCP2 KIFAP3 MAD2L1BP NPM1 PARP4 RCC2	up	***
GO_ORGANELLAR_RIBOSOME	0.0001371	0.0049434	0.5188481	0.4421521	1.775968	80	MRPL46 MRPS35 MRPL15 MRPL3 MRPL27 MRPS11 MRPS30 MTG1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 CHCHD1 C12orf65 MRPL24 MRPS33 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPL55 MRPL9 MRPL21 MRPS27 MRPL20 MRPL48 MRPS26 MTG2 MRPS16 MRPL12 MRPL43 MRPL2 MRPS6	up	**
GO_PYRIMIDINE_RIBONUCLEOTIDE_METABOLIC_PROCESS	0.0030817	0.0477205	0.4317077	0.5948911	1.775894	20	UMPS NME1 NME9 NME5 CAD UCK2 UCKL1 UPP2 DHODH NME4 NME7	up	*
GO_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION	0.0015605	0.0301797	0.4550599	-0.4229638	-1.775002	50	SMAD6 ACVRL1 BMPER BMP2 ENG BMPR2 TGFBR3 TGFBR2 NODAL SDCBP DAB2 SMAD7 INHBA TGFB2	down	*
GO_MITOTIC_METAPHASE_PLATE_CONGRESSION	0.0019254	0.0343514	0.4550599	0.4991257	1.772758	42	CCNB1 NDC80 KIF14 NUF2 CDCA8 CDT1 SPDL1 BOD1 KIF2C MAD1L1 CDCA5 PSRC1 KPNB1 CDC23 KIF22 CHMP4C NUP62 CHMP1A CHMP2A CENPE RRS1 CHMP6	up	*
GO_4_IRON_4_SULFUR_CLUSTER_BINDING	0.0023356	0.0391219	0.4317077	0.5040323	1.771898	40	DDX11 PRIM2 POLE NDUFS2 BRIP1 ERCC2 TYW1 DNA2 POLD1 NDUFS7 NDUFV1 RTEL1 CDK5RAP1 NUBP2 RSAD1 NDUFS8 NUBPL CIAPIN1 CDKAL1 DPYD RSAD2	up	*
GO_PYRIMIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS	0.0014105	0.0278630	0.4550599	0.4955266	1.770602	44	CPS1 GPAT2 TYMS UMPS TAMM41 NME1 NME9 NME5 CAD UCK2 UCKL1 UPP2 MTOR DHODH TK1 DTYMK AGPAT5 LCLAT1	up	*
GO_CILIARY_BASAL_BODY	0.0002444	0.0079126	0.4984931	0.4231568	1.769325	97	PKHD1 RPGRIP1L CENPF MKS1 FANK1 IFT122 TTC26 CEP250 BBS1 FBF1 POC1A AGBL4 IFT172 GAS8 CBY1 RABEP2 C2CD3 DLG5 CENPJ KIF7 SSX2IP POC1B LCA5 IFT52 BBS5 TUBG1 CCDC151 TRAF3IP1 AGBL2 WDR34 ODF2L WDR35 NEK4 FAM161A TBC1D30 TTLL6 B9D1 ICK MARK4	up	**
GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION	0.0001415	0.0050669	0.5188481	0.4140530	1.765865	114	TRIP13 BUB1B CCNB1 CENPF NDC80 PIF1 BRCA1 TTK DNMT3B PLK1 AURKB PTTG1 ESPL1 MCM2 CDT1 SPDL1 SDR16C5 BUB1 TOP2A TPR MAD1L1 MAD2L1 XRCC1 PIH1D1 PRMT6 MNAT1 PARP1 MAD2L2 KLHL22 DNMT1 NOC2L SLX4 RAD50 KDM3A CDC20 TWIST1 HMGA1 CDK5RAP2	up	**
GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION	0.0000646	0.0027611	0.5384341	-0.3450663	-1.765161	132	SWAP70 PHACTR1 DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 INPP5K BAG4 BAIAP2 S1PR1 CDC42 NEDD9 RHOA SPIRE1 LCP1 RGCC SFRP1 SORBS3 RHOB ROCK2 ARRB1 SYNPO SORBS1 ROCK1 MYO1B PLEK ADD1 SRF FAM107A WASF2 SYNPO2 RHOBTB2 ARHGEF10 PTGER4 PIK3R1 PPM1F ESPNL WNT11	down	**
GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION	0.0000531	0.0023712	0.5573322	-0.3423130	-1.764428	142	FFAR4 RAB11FIP1 ADTRP IL1B INSIG1 INPP5K BAG4 HMGCR GAS6 CD22 APOD CD36 ANXA1 MIR146A CARD16 ANXA5 PPP3CA RGCC SFRP1 SRGN TXN IL10 REST KLF7 DPH3 MIR24-2 FRMD4A SNX3 PKIG CARD8 DNAJA1 PTGER4 UBAC2 PPM1F CD34 PKIA SERPINB1 LRRC32 SYT11 NLRP3 SP100 PSMD9 ENY2 BANK1 PIM3 ACVR1C CHP1 C5AR2 KCNE1 FKBP1B	down	**
GO_ENDOCYTIC_VESICLE_MEMBRANE	0.0000758	0.0031399	0.5384341	-0.3500899	-1.763155	124	RAB11FIP1 MCOLN1 HVCN1 WNT4 CAV1 MARCO CD9 LAMP1 SLC11A1 SCARF1 CD36 HBEGF RILP PICALM FZD4 WNT3A MSR1 NOSTRIN ATP6V0D2 EPS15 HLA-DQA1 ANXA3 TBC1D5 VAMP3 INPP5B SNAP23 RAB8B RAB31 RAC2 ATP6V0B RAPGEF1 RAB8A GRIA1 ATP6V0D1 UBB CD74 PIK3C3 ATP6V0C	down	**
GO_OUTER_DYNEIN_ARM_ASSEMBLY	0.0015748	0.0302342	0.4550599	0.6860340	1.763115	12	DNAI1 ARMC4 CCDC114 DNAH8 LRRC6 DNAH5 CCDC151 DNAI2 ZMYND10 DNAAF1 DNAL1	up	*
GO_CHEMOKINE_PRODUCTION	0.0006748	0.0168031	0.4772708	-0.3919369	-1.757648	67	HMOX1 IL1B LPL IL1RL1 APOD MIR146A ADAM17 CLEC7A FOXP1 SIRPA IL10 MEFV KLF4 SOCS5 TLR4 IL6 MBP CD74 CHIA IL18 RIPK2 HAVCR2 EPHA2 MCOLN2 EGR1 C5 TREM2 S100A8 MUL1 WNT5A	down	*
GO_CILIUM	0.0000000	0.0000027	0.7337620	0.3574710	1.754921	440	PKHD1 STRC KLC3 CNGA1 CEP89 DNAH2 PMFBP1 RPGRIP1L PROM1 CENPF IQCE CIB2 MKS1 SORD FANK1 IFT122 CATSPERB DAW1 SPAG17 TTC26 IFT27 DNAH3 GUCA1B KIF27 DNAH14 AK8 DNAI1 NPFFR1 CEP250 RSPH1 TTLL4 ARMC4 BBS1 SPAG16 TSGA10 KIF3B FBF1 AURKA IQCD ODF2 IFT43 HAVCR1 POC1A HYDIN AGBL4 WDR78 TEKT2 KISS1R CCDC114 PKM DCDC2 PEX6 WDR66 WDR60 NME5 DNAH8 SLC9A3R1 PROM2 IFT172 GAS8 KIF3C CBY1 CNGB1 DNAH11 RABEP2 C2CD3 TRPV4 DLG5 TULP3 CCDC40 DRC1 LRRC6 IQCB1 CROCC DNAH6 KIF5A CENPJ MERTK TTLL9 KIF19 SPAG6 TCTN2 KIF2A KIF7 SSX2IP DYNLL2 POC1B SMO LCA5 NAPEPLD AK7 DNAH5 LRRC56 TCTE1 ABCA4 TMEM231 IFT52 CATSPERG ELMOD3 SPEF1 EVC2 BBS5 CATSPER3 NPHP1 TUBG1 DNAH7 EFCAB2 MNS1 CCDC151 IQCG SPTBN5 TMEM237 CNGA4 TEKT3 SPA17 CEP128 TRAF3IP1 CLTB DNAJB13 EFCAB7 AGBL2 IQUB ROPN1B WDR34 TTLL3 EFHC1 TCTN1 CATSPER2 RPGRIP1 ODF2L FAM183A DNAI2 RAB15 ANKS3 WDR35 DYNC2H1 NEK4 FAM161A TBC1D30 TTLL6 RSPH4A UNC119B RAB34 SPAG4 TMEM17 CATSPER1 B9D1 ALMS1 ICK CEP164 CCDC181 CLUAP1 NUBP2 DNAH1 MARK4 ENKUR TBC1D32 TACR1 ADCY6 ANKMY2 ADAM15 PDZD7 DHRS3 UBXN10 ANKS6 TSSK4	up	***
GO_REGULATION_OF_CENTROSOME_CYCLE	0.0007501	0.0181424	0.4772708	0.4774011	1.754232	52	PKHD1 SPICE1 MDM1 NEK2 BRCA1 STIL CCNF RANBP1 CEP250 AURKA POC1A KIF11 CHEK1 CENPJ TRIM37 CHMP4C CDK5RAP2 NUP62 CEP85 ALMS1 CHMP1A MARK4 CHMP2A	up	*
GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS	0.0013663	0.0272032	0.4550599	0.4607658	1.754172	60	AK4 GMPS TYMS UMPS AK8 DNPH1 DLG1 CARD11 CAD LRGUK UCK2 ATIC AK7 UCKL1 UPP2 DHODH TK1 DTYMK NT5M RAD50 PFAS ENTPD8 LHPP PNKP GMPR2 PAICS TK2 DGUOK ADSL APRT AK9 SHMT1 CMPK2	up	*
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0002742	0.0085488	0.4984931	0.4303636	1.752708	86	HMGA2 TICRR BRCA1 BRSK1 PLK1 AURKB CDC6 ORC1 DTL ZFYVE19 CDK5RAP3 AURKA CLSPN TOPBP1 CHEK1 PSMD4 BLM CDK1 PSMB5 PSMC4 PSMA5 PSME2 FZR1 PSMD2 PSMB3 CHMP4C UIMC1 PSMB4	up	**
GO_MITOCHONDRIAL_LARGE_RIBOSOMAL_SUBUNIT	0.0007886	0.0187594	0.4772708	0.4761465	1.749622	52	MRPL46 MRPL15 MRPL3 MRPL27 MRPS30 MRPL36 MRPL37 MRPL17 MRPL11 MRPL52 MRPL4 C12orf65 MRPL24 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPL55 MRPL9 MRPL21 MRPL20 MRPL48 MRPL12 MRPL43 MRPL2 MRPL35 MRPL13 MRPL33 MRPL19 MRPL38 NSUN3 MRPL10 MRPL23	up	*
GO_SPINDLE_POLE	0.0000803	0.0032670	0.5384341	0.3950392	1.747976	145	DDX11 CEP89 NEK2 CCNB1 CENPF ASPM PLK1 AURKB CDC6 TPX2 PRC1 DYNC1I1 SPDL1 WDR62 BOD1 KNTC1 AUNIP FBF1 MAP10 AURKA ODF2 MAD1L1 POC1A WDR73 KIF11 GPSM2 WDR60 TOPBP1 MAD2L1 CKAP2L PSRC1 KNSTRN KIF2A SPAG5 POC1B KLHL22 CEP63 TUBG1 DLGAP5 TACC3 PKP4 KIF20B CEP128 CKAP5 CDC20 AAAS EFHC1 CDK5RAP2 CKAP2 FAM161A KATNB1 NUP62 CEP85 ALMS1 TUBGCP4 NUBP2	up	**
GO_GDP_BINDING	0.0016731	0.0315035	0.4550599	-0.3956919	-1.747870	61	ARL8B RHOA RRAGC RAP1A RAB14 RHOB RAB12 RIT1 RASL12 RAB8B RAB31 RAB8A RALB RRAS GNAI1 DYNC1LI1 GEM RAB5A	down	*
GO_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS	0.0031269	0.0477956	0.4317077	-0.4293299	-1.747810	45	TEK GATA2 RAMP2 ECSCR BMPR2 GAS6 GATA3 RGCC NFE2L2 IL10 THBS1 MIR24-2 CD160 NDNF	down	*
GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_CELL_CYCLE_CHECKPOINT	0.0005532	0.0147139	0.4772708	0.4515211	1.746908	67	CHEK2 CCNB1 BRCA1 E2F8 GTSE1 PLK1 TFDP2 DTL CASP2 AURKA PRKDC CDC25C SOX4 CHEK1 SOX11 MDM2 PML CNOT3 CDK1 E2F1 CNOT11 CNOT2 FZR1	up	*
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.0008369	0.0195671	0.4772708	-0.3722193	-1.745327	80	CD55 SPN TGFBR2 IL23A ANXA1 FOXP1 HLX GATA3 IL18R1 FUT7 SOCS5 SMAD7 NCKAP1L CD80 IL6 CD160 PTGER4 CD83 GPR183 MALT1 RC3H1 TBX21 RUNX3 CD86 CD81 IL18 SEMA4A RIPK2 NLRP3	down	*
GO_PRONUCLEUS	0.0020458	0.0354997	0.4317077	0.6779687	1.742387	12	CENPF SLC2A1 AURKA EZH2 CBX1 CCNA2	up	*
GO_COHESIN_COMPLEX	0.0020752	0.0358264	0.4317077	0.6778478	1.742076	12	DDX11 STAG3L2 STAG3 REC8 CDCA5 STAG3L4	up	*
GO_NEGATIVE_REGULATION_OF_TRANSPORT	0.0000000	0.0000072	0.7195128	-0.2996956	-1.741294	368	FFAR4 RAB11FIP1 CD300LF FOXF1 HMOX1 ADTRP SFRP4 IL1B PRKG2 P2RY1 PLA2G10 PID1 INSIG1 PCSK9 STXBP6 INPP5K BAG4 CAV1 NEDD4L HMGCR MIR27B GAS6 CD22 KCNAB1 APOD CD36 ANXA1 MIR146A CARD16 MCTP1 ADA CD33 HECW2 RAP1A RAB33B PICALM ANXA5 PPP3CA SIRPA RGCC SFRP1 SRGN TXN APOC1 IL10 FABP5 SDCBP TACR2 REST THBS1 KLF7 UBQLN1 DPH3 NFKB1 MIR24-2 FRMD4A PTGER3 INHBA OXSR1 GNAI2 TBC1D4 CALM2 SNX3 PKIG ARL6IP5 VAMP3 LRRTM2 APPL1 NOTCH1 CARD8 GSTO1 PTGER4 UBAC2 PRKCE OSM PXK PPM1F CD34 CALM1 ATG3 PKD2 PKIA CD74 EPHA3 NUP153 STXBP3 PEA15 SERPINB1 HECW1 MTMR2 LRRC32 IRS2 MPV17L LGALS3 ANKRD13A CRY1 ACTN2 RGS2 SYT11 GEM ICAM1 CTTNBP2NL OSR1 VPS4B NLRP3 SP100 ISCU BOK SREBF2 EDN1 PTEN NRG1 GRB10 PSMD9 ENY2 ATF4 BANK1 PIM3 KALRN ACVR1C CHP1 C5AR2 KCNE1 FKBP1B CRBN	down	***
GO_MITOCHONDRIAL_MATRIX	0.0000001	0.0000118	0.7049757	0.3564691	1.739197	396	CPS1 AK4 BDH1 GPT2 CCNB1 TSFM NMNAT3 TBRG4 THEM4 THEM5 MRPL46 FLAD1 TYMS GLDC SHMT2 MRPS35 COQ3 NDUFB8 NUDT1 MRPL15 PCCB NDUFS2 LARS2 COASY ERAL1 MRPL3 MRPL27 BLOC1S1 MCCC2 PYCR2 TARS2 SARS2 TRMT61B ACSF2 MRPS11 ETFA FDXR MRPS30 MTG1 TST IDH2 TRIT1 MRPL36 FASTK HARS2 MRPL37 CDK1 SSBP1 NUDT2 DMGDH GOT2 OAT ACP6 TRAP1 MCAT DNA2 MRPS2 MRPL17 PDK1 MECR MRPS12 LIPT2 ETFB ATAD3A UQCC2 HYKK PARS2 NADK2 NFS1 DNAJA3 PUS1 ALDH7A1 MRPS34 LONP1 MRPL11 MRPL52 DTYMK MRPL4 ACAD10 DAP3 GFM2 GSTK1 ELAC2 NT5M YARS2 DHTKD1 CHPF NAGS IARS2 CHCHD1 SIRT4 C12orf65 LRRC59 FAHD1 BCL2L1 NAT8L PHYKPL MRPL24 MRPS33 MRPL28 MRPL41 HIBADH ACOT11 SIRT5 MALSU1 MRPL53 PRODH NDUFS7 AMT MRPL51 SUOX PYCR1 MRPL14 SCO2 VDAC1 MRPL55 NME4 ABHD10 ACSF3 RAD51 GADD45GIP1 ATG4D OXCT1 ECHS1 MRPL9 MRPL21 NDUFS8 NUBPL ETHE1 PARG EARS2 MPG TP53 TIMM44 MRPS27 PDP1 BCAT2 MRPL20 MRPL48 TK2 MRPS26 TRUB2 ACAD8 CYP11A1 MTG2 RPUSD3 TFB1M SARDH BCKDK POLRMT MRPS16 ACSM3 DGUOK TOP3A PDK2 MRPL12 CLPP MRPL43 SDHAF1 MRPL2 MCEE GLRX5 COQ5 MPST TEFM GCSH MRPS6 D2HGDH MARS2 CS TXN2 PC LRPPRC MCCC1 MTHFD2	up	***
GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH	0.0003721	0.0107502	0.4984931	-0.3658531	-1.738857	91	SLC6A4 TNR RBP4 SEMA6B SEMA3G SEMA6A TGFBR2 SEMA6D WWC2 MYOZ1 SEMA3B ADRB1 ADRB2 SFRP1 WNT3A TRIM46 SOCS2 CDKN1A TBX5 MIR17HG IFRD1 RTN4R SAV1 MEIS1 RGS2 SEMA4A RTN4 PTCH1 ULK2 STK4 PTEN	down	*
GO_HARD_PALATE_DEVELOPMENT	0.0018650	0.0338100	0.4550599	0.8330175	1.738474	6	FOXE1 DLG1 SOX11	up	*
GO_INTRACILIARY_TRANSPORT	0.0018504	0.0336482	0.4550599	0.4838010	1.738394	46	IFT122 TTC26 IFT27 KIF3B IFT43 WDR60 IFT172 KIF3C SSX2IP DYNLL2 LCA5 IFT52 TRAF3IP1 WDR34 WDR35 DYNC2H1 ICK CLUAP1 TTC30B MAK KIFAP3 BBS12 KIF3A IFT81 IFT74 TCTEX1D2 SSNA1 IFT80 TTC30A LCA5L TUB IFT57 IFT140	up	*
GO_T_CELL_MIGRATION	0.0020924	0.0360612	0.4317077	-0.4098626	-1.737400	51	CXCL16 GPR15 SPN S1PR1 RHOA APOD ADAM17 CRK CCL3 XCL2 OXSR1 LRCH1 GPR183 DOCK8 ADAM10 CCL20 CCR6 ICAM1	down	*
GO_RESPONSE_TO_WOUNDING	0.0000000	0.0000001	0.8266573	-0.2926778	-1.736691	527	TNR AJAP1 CLEC1B EREG ACVRL1 IL1A FOXF1 HMOX1 PECAM1 CCM2L ADTRP HHEX GATA2 WFDC1 F2RL3 WNT4 P2RY1 LYVE1 THBD RCOR1 TRPC3 FOLR1 FYN MMRN1 CD44 CAV1 TBXA2R HMGCR FGF10 PRKAR1A CDC42 CD9 GAS6 SLC11A1 TGFBR2 SCARF1 HPS5 PEAR1 RHOA APOD CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 ADAM17 ENTPD1 CLEC7A CSRP1 ITGA5 HSPB1 ANXA5 SLC7A11 GATA3 PPP3CA JAM3 NFE2L2 NDEL1 GRN CRK WNT3A SGCA PDGFA FOXC2 PTPN12 GPR4 IL10 ARRB1 DGKE KLF4 PLAUR ID3 THBS1 MAFG MPL ITPK1 DOCK9 CDKN1A SELP AXL HPSE TLR4 CAPZA2 FCER1G ELK3 PLEK ADIPOR2 MATN2 GNAQ UBASH3B PIK3R5 C4BPB MAFF IL24 AKIRIN1 KREMEN1 VWF TGFB2 STK24 PROCR MTPN SRF NINJ1 PRCP KANK1 CNTF METAP1 IL6 LAMB2 NDNF JUN NOTCH1 ETS1 TYROBP DUOX1 ENPP4 IFRD1 PIK3R1 PABPC4 PRKCE RTN4R PRKACA DOCK8 AP3B1 YWHAZ MCAM CD34 PLCG2 CD151 EHD2 SRSF6 PRKCG EPPK1 MYL12A DGKG STXBP3 TGFB1 EHD1 VAV3 ITGA9 TEC NLRP6 MIA3 CD81 CCR1 CLASP2 GATA6 GNA13 MACF1 TSPO SMAD2 DOCK6 SYT11 FGF2 CPQ VASH1 TFPI ARRB2 RAB5A CXCR4 EPHA4 ACTB ADORA2A JMJD1C MAFK EDN1 SCUBE1 PTEN PRKG1 P2RX1 NRG1 ZFPM2 EHD3 ANO6 PAPSS2 IRF2 SERPINE1 CDKN1B FKBP1B TREML1 CAPZB CX3CR1 MAPK1 PRKCH MYH10 S100A8 ZFP36 CD109 NOG	down	***
GO_CENTROSOME_DUPLICATION	0.0009320	0.0211130	0.4772708	0.4608409	1.736149	58	PKHD1 CEP72 SPICE1 MDM1 BRCA1 BRSK1 STIL CCNF WDR62 POC1A C2CD3 CENPJ KIAA0753 CEP63 CEP192 TRIM37 SASS6 CKAP5 CHMP4C CDK5RAP2 CEP152 NUP62 ALMS1 CHMP1A CHMP2A	up	*
GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	0.0000259	0.0013739	0.5756103	-0.3350853	-1.736029	158	FOXF1 HMOX1 SCIMP GATA2 IL1B CLEC12B PRAM1 CD1C LAMP1 IL23A FGR DNASE1L3 CLCF1 SERPINB9 GATA3 IL18R1 TRAF6 CRK CRTAM TFRC IL10 PTAFR FAM49B CADM1 PTPRC TLR4 FCER1G SMAD7 IL7R C4BPB IL6 CD160 RAC2 STX7 MALT1 TBX21 TNFSF13 CR1 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT UNC13D IL18 IL18RAP ARRB2 NLRP3 HAVCR2 CD1E KLRK1	down	**
GO_LIGASE_ACTIVITY	0.0005438	0.0145599	0.4772708	0.4098955	1.734640	108	CPS1 UCHL1 SLC27A2 GMPS AACS LIG3 AARS2 TTLL4 BTRC PCCB SAE1 LARS2 MCCC2 TARS2 LIG1 SARS2 ASS1 ACSF2 MDM2 CAD HARS2 TTLL9 ACSBG2 LIPT2 RTCB PARS2 GSS AARSD1 ASNS ACSL6 NADSYN1 YARS2 PFAS IARS2 TTLL3 TTLL6 FARSA ACSF3 HLCS FARSB EARS2 MTHFD1 PAICS TTLL5 ACSL5 ACSBG1 ACSM3 SLC27A5 MARS2 NAE1 PC MCCC1 CARNS1 CTPS1 SLC27A1 DARS2 GCLC SUCLG1 NARS2 MTHFS GART TTLL1 ACSS2 UBA2 ACSS3	up	*
GO_DNA_POLYMERASE_ACTIVITY	0.0027224	0.0437919	0.4317077	0.5375168	1.733225	27	POLQ POLE POLM POLA2 POLD2 POLN TERC POLE2 TEP1 POLL POLD1 POLB	up	*
GO_WOUND_HEALING	0.0000000	0.0000004	0.7881868	-0.2989037	-1.730520	436	AJAP1 CLEC1B EREG ACVRL1 IL1A HMOX1 PECAM1 CCM2L ADTRP GATA2 WFDC1 F2RL3 WNT4 P2RY1 THBD RCOR1 TRPC3 FYN MMRN1 CD44 CAV1 TBXA2R HMGCR FGF10 PRKAR1A CDC42 CD9 GAS6 SLC11A1 TGFBR2 HPS5 PEAR1 RHOA APOD CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 ADAM17 ENTPD1 CLEC7A CSRP1 ITGA5 HSPB1 ANXA5 SLC7A11 GATA3 PPP3CA NFE2L2 CRK WNT3A SGCA PDGFA FOXC2 PTPN12 GPR4 ARRB1 DGKE PLAUR THBS1 MAFG MPL ITPK1 DOCK9 CDKN1A SELP AXL HPSE TLR4 CAPZA2 FCER1G ELK3 PLEK ADIPOR2 GNAQ UBASH3B PIK3R5 C4BPB MAFF IL24 AKIRIN1 VWF TGFB2 PROCR MTPN SRF NINJ1 PRCP KANK1 METAP1 IL6 NDNF NOTCH1 ETS1 DUOX1 ENPP4 IFRD1 PIK3R1 PABPC4 PRKCE PRKACA DOCK8 AP3B1 YWHAZ MCAM CD34 PLCG2 CD151 EHD2 SRSF6 PRKCG EPPK1 MYL12A DGKG STXBP3 TGFB1 EHD1 VAV3 ITGA9 TEC NLRP6 MIA3 CD81 CLASP2 GATA6 GNA13 MACF1 SMAD2 DOCK6 SYT11 FGF2 CPQ TFPI ARRB2 RAB5A CXCR4 ACTB ADORA2A JMJD1C MAFK EDN1 SCUBE1 PTEN PRKG1 P2RX1 NRG1 ZFPM2 EHD3 ANO6 PAPSS2 IRF2	down	***
GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT	0.0000244	0.0013157	0.5756103	-0.3307665	-1.730127	169	ANGPT4 TMEM100 ACVRL1 IL1A SASH1 HMOX1 TEK GATA2 IL1B TIE1 RAPGEF2 BMPER RAMP2 CDH5 ENG TBXA2R C5AR1 MIR27B TGFBR2 ANXA1 MIR146A RAP1A ITGA5 HSPB1 NFE2L2 GRN AKT3 FOXC2 NODAL RHOB IL10 TNFSF12 KLF4 THBS1 ITGAX PIK3C2A PTGIS ANXA3 BTG1 FLT1 NOTCH1 ETS1 JAK1 RHOJ	down	**
GO_MITOTIC_SPINDLE_MIDZONE_ASSEMBLY	0.0025715	0.0419642	0.4317077	0.8761283	1.729192	5	RACGAP1 AURKB KIF23 MAP10	up	*
GO_GALACTOLIPID_BIOSYNTHETIC_PROCESS	0.0025715	0.0419642	0.4317077	0.8759850	1.728909	5	UGT8 GAL3ST1 FA2H	up	*
GO_INTERSTRAND_CROSS_LINK_REPAIR	0.0025649	0.0419642	0.4317077	0.4800324	1.728714	45	FANCI UBE2T MCM8 FANCA EME1 ATR FANCD2 RAD51AP1 POLN RFWD3 FANCG DCLRE1C FANCF RAD51D SLX4 RPA1 FANCM RAD51 MUS81 ATRIP RNF8 DCLRE1B MSH6 DCLRE1A	up	*
GO_PROTEIN_LOCALIZATION_TO_CYTOSKELETON	0.0011476	0.0241867	0.4550599	0.4704282	1.728610	52	CEP72 NUDCD3 TTK ANLN CCDC14 STIL GOLGB1 DCTN2 CEP250 BICD1 AURKA C2CD3 ABHD17C KIAA0753 SPAG5 CEP192 KIF20B	up	*
GO_HAPTOGLOBIN_HEMOGLOBIN_COMPLEX	0.0027293	0.0438328	0.4317077	0.8748812	1.726731	5	HP HBA1 HBA2 HBB	up	*
GO_REGULATION_OF_COLLAGEN_METABOLIC_PROCESS	0.0027870	0.0442680	0.4317077	-0.4532760	-1.725804	33	PPARG WNT4 ENG RAP1A RGCC CST3 VIM IL6 MFAP4 TGFB1 CYGB ARRB2	down	*
GO_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.0000273	0.0014236	0.5756103	-0.3305807	-1.723283	173	RBP4 CCM2L TBX3 BMP2 SIK1 ENG S1PR1 PRKAR1A MEF2A CDC42 TGFBR3 TGFBR2 HEG1 JPH2 TBX2 LMNA WNT3A HNRNPU TCAP FOXC2 TNNC1 ADAMTS9 ID2 MIR24-2 SMAD7 ZMPSTE24 TBX5 MYH11 MIR17HG TGFB2 SRF RBPJ SLC8A1 NOTCH1 ADRA1A CREB1 NDUFV2 CACYBP SAV1 TGFB1 MIR23A PIM1 MEIS1 MYOCD GATA6 ACTN2 RGS2 RXRA FGF2 PDLIM5 FKBP1A ARRB2 EDN1 PTEN FGFR1 MIR548C NRG1 ZFPM2 SMAD4 GREM1 GJC1 MAPK1 MYH10 ITGB1 NOG EFNB2 CALR WNT5A PLN	down	**
GO_REGULATION_OF_MEMBRANE_REPOLARIZATION_DURING_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.0029817	0.0468473	0.4317077	0.8722094	1.721457	5	NOS1AP DLG1 KCNE3 RNF207	up	*
GO_CATALYTIC_ACTIVITY_ACTING_ON_A_TRNA	0.0011665	0.0244246	0.4550599	0.4183284	1.720923	91	METTL1 AARS2 QTRT1 LARS2 NSUN2 TRPT1 TARS2 SARS2 TRMT61B TRIT1 HARS2 DTD1 TYW1 PARS2 PUS1 AARSD1 TSEN54 ELAC2 YARS2 IARS2 DUS1L POP7 METTL2B NSUN6 DUS4L RPP38 DUS2 FARSA WDR4 FARSB TARBP1 EARS2 POP4 CDKAL1 DTD2	up	*
GO_INTERLEUKIN_12_PRODUCTION	0.0028533	0.0451804	0.4317077	-0.4141974	-1.717114	47	ACP5 SCIMP IL23A CD36 CLEC7A FOXP1 TRAF6 IL10 MEFV THBS1 NFKB1 TLR4 CCR7 IRF8 TIGIT IRF5 ARRB2 RIPK2	down	*
GO_LEUKOCYTE_HOMEOSTASIS	0.0011794	0.0245626	0.4550599	-0.3769168	-1.716824	74	GAPT HCAR2 ANXA1 SH2B3 ADA ADAM17 SLC7A11 JAM3 SLC46A2 MPL AXL FCER1G MIR17HG NCKAP1L IL6 SKIL GPR183 RC3H1 CD74 PDE4B LAT DOCK10 PMAIP1 PPP2R3C BCL10 HMGB1 RC3H2 CASP3 BAP1 FLT3	down	*
GO_POSITIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT	0.0017761	0.0327852	0.4550599	-0.4005311	-1.715927	56	HMGCR TGFBR3 TBX2 WNT3A ARNTL TBX5 CYP26B1 MIR17HG LMOD3 RBPJ NOTCH1 CREB1 TGFB1 PIM1 MYOCD GATA6 FGF2 ARRB2 EDN1 FGFR1 MIR548C NRG1 ZFPM2 GREM1 CDON MAPK1 EFNB2	down	*
GO_MITOCHONDRIAL_PROTEIN_COMPLEX	0.0000348	0.0017248	0.5573322	0.3722871	1.714533	207	CHCHD6 MRPL46 ANKZF1 NDUFS6 MRPS35 AGK NDUFB8 SDHA MRPL15 NDUFS2 MRPL3 MRPL27 MCCC2 TIMM50 MRPS11 MRPS30 MRPL36 MRPL37 DNA2 MRPS2 MRPL17 PDK1 MRPS12 CHCHD3 UQCRFS1 NDUFA11 SPG7 COA3 FOXRED1 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 DNAJC11 NDUFA13 TIMM13 C12orf65 MRPL24 MRPS33 MRPL28 MRPL41 ROMO1 MALSU1 MRPL53 NDUFS7 MRPL51 NDUFV1 MRPL14 VDAC1 MRPL55 UQCRC1 TOMM40L MCU MRPL9 MRPL21 MICU1 NDUFA8 NDUFS8 UQCRQ MRPS27 MRPL20 MRPL48 NDUFB7 MRPS26 IMMP2L BCKDK TOMM7 POLRMT MRPS16 PDK2 MRPL12 MRPL43 MRPL2 TOMM40 TIMM10 MRPS6 NDUFB2 TIMM9 MCCC1 COX6A1 NDUFA4L2 NDUFA9 SDHC WDR93 MRPS7 MRPL35 MRPL13 MRPL33 NDUFA10 BCKDHA MFN1 NDUFB10 TIMM23 IMMP1L NDUFS4	up	**
GO_MYOBLAST_DIFFERENTIATION	0.0015355	0.0298663	0.4550599	-0.3834909	-1.714149	68	EPAS1 SOSTDC1 TBX3 HMGCR KCNAB1 TBX2 RB1 TCF7L2 REST ID3 PLEKHM3 AKIRIN1 SRF BTG1 RBPJ NOTCH1 DDX17 IFRD1 DDX5 TGFB1 MYOCD MBNL1 IL18	down	*
GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.0000998	0.0038468	0.5384341	-0.3304240	-1.714010	143	SWAP70 GAPT SPN CD1C LAMP1 SLC11A1 IL23A ANXA1 CLCF1 ADA FOXP1 HLX LCP1 IFNK GATA3 IL18R1 TFRC IL10 SOCS5 PTPRC TLR4 FCER1G SMAD7 CD80 IL6 PSEN1 PTGER4 GPR183 MALT1 RC3H1 TBX21 ZNF683 PLCG2 TNFSF13 TGFB1 AP1G1 CD86 CD81 LGALS3 MFNG UNC13D CCR6 ICAM1 IL18 NBN SEMA4A RIPK2 NLRP3 HAVCR2 CD19 DOCK10 RORA	down	**
GO_NEGATIVE_REGULATION_OF_PEPTIDE_SECRETION	0.0004303	0.0121129	0.4984931	-0.3582763	-1.713169	98	FFAR4 RAB11FIP1 ADTRP IL1B HMGCR GAS6 CD22 ANXA1 MIR146A CARD16 ANXA5 PPP3CA RGCC SFRP1 SRGN IL10 REST KLF7 DPH3 MIR24-2 FRMD4A CARD8 PTGER4 CD34 CD74 SERPINB1 LRRC32 SYT11 NLRP3 PSMD9 ENY2 BANK1 PIM3 KALRN ACVR1C C5AR2 FKBP1B	down	*
GO_SM_LIKE_PROTEIN_FAMILY_COMPLEX	0.0016310	0.0309525	0.4550599	0.4469867	1.711861	63	LSM5 GEMIN7 GEMIN4 PRPF6 SNRPE EFTUD2 SNRPA GEMIN5 GEMIN6 CD2BP2 SNRPD1 LSM7 DDX23 LSM4 TXNL4A SF3A2 PRPF18 SNRPD2 TXNL4B USP39 PRPF31 SNRNP70 SNRNP200 ZMAT2 PRPF3 SNRPC SF3B2 SART1 SART3 GEMIN2 CLNS1A LUC7L3	up	*
GO_NODE_OF_RANVIER	0.0028994	0.0457670	0.4317077	0.6660430	1.711738	12	SPOCK1 DLG1 NFASC SCN8A ANK3 CNTN2 KCNQ3	up	*
GO_MEIOTIC_CHROMOSOME_SEGREGATION	0.0018527	0.0336482	0.4550599	0.4552161	1.711226	56	TRIP13 BUB1B TTK PLK1 NUF2 PTTG1 ESPL1 STAG3 BUB1 TOP2A EME1 REC8 SYCP2 FANCD2 HORMAD1 EME2 BRIP1 SUN1 CCNE1 SLX4 ANKRD31 MEI1 FANCM	up	*
GO_NEGATIVE_REGULATION_OF_LOCOMOTION	0.0000008	0.0000728	0.6594444	-0.3041976	-1.709501	275	ANGPT4 SEMA6B SEMA3G SEMA6A ACVRL1 HMOX1 DLC1 PPARG ADTRP TIE1 WNT4 ENG CORO1C CITED2 TBXA2R TRIB1 RHOA APOD SEMA6D MIR146A MMRN2 PTPRM MCTP1 SEMA3B ADA ADIPOR1 ABHD6 DACH1 GATA3 RGCC NFE2L2 CRK SFRP1 WNT3A NODAL RHOB ADARB1 DUSP3 PTPRO KLF4 THBS1 ADAMTS9 CLDN5 CLIC4 MIR24-2 RECK DUSP1 SMAD7 TBX5 IL24 ARHGDIB STK24 GNRH1 SRF SRGAP2C KANK1 PODN MAGI2 MITF LRCH1 NOTCH1 PTGER4 RRAS FOXO3 EPPK1 CD74 WNT11 TGFB1 CYGB MIA3 KLRC4-KLRK1 MYOCD CLASP2 GPR18 LDLRAD4 FGF2 VASH1 CHMP3 SEMA4A SP100 LIMCH1 ADORA2A SCAI KLRK1 PTEN PRKG1 NRG1 STARD13 ACVR1C GREM1 SERPINE1 C5AR2 CX3CR1 C5 PIP5KL1 NOG MIR640 MIR2355 CALR WNT5A ANGPT2 TRIM13 HMGB1	down	***
GO_LYSOSOMAL_LUMEN	0.0008607	0.0198233	0.4772708	-0.3686057	-1.708638	78	LIPA GPC5 MANBA FUCA1 HSPG2 MAN2B1 ARSB ASAH1 NAAA GM2A IFI30 PRELP PPT1 GAA TPP1 CTSD HPSE GLB1 HEXB CTSS	down	*
GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION	0.0000220	0.0012078	0.5756103	-0.3245047	-1.705690	177	SLC6A4 TNR DAB1 SEMA6B SEMA3G SEMA6A EDNRB DENND5A RAPGEF2 DDX6 CTDSP1 RHOA SEMA6D ASAP1 SEMA3B PAQR3 EIF4E PPP3CA WNT3A ZNF365 LRP4 PTPRO TRIM46 REST ID3 VIM ID2 PAFAH1B1 RUFY3 HES1 KREMEN1 SRGAP2C KANK1 MYLIP ID4 CNTF PSEN1 NOTCH1 CTSZ CNTN4 BAG5 IFRD1 LSM1 RTN4R TRAK2	down	**
GO_NEGATIVE_REGULATION_OF_MESODERM_DEVELOPMENT	0.0009896	0.0220419	0.4550599	0.9234753	1.703040	4	DKK1 TP63	up	*
GO_MICROTUBULE	0.0000003	0.0000311	0.6749629	0.3507614	1.701621	360	KIF1A SAA1 KIF12 KLC3 KIF20A MDM1 DNAH2 RPGRIP1L NEK2 KIF18B TUBB2B RACGAP1 GTSE1 KIF14 SPAG17 ASPM PLK1 AURKB TPX2 DNAH3 PRC1 DYNC1I1 CCT6A KIF27 CDK5RAP3 DNAH14 CCT2 DCTN2 DNAI1 HAUS5 TTLL4 DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 KNTC1 KIF3B MAP10 CCT5 AURKA ODF2 KIF2C MAP1LC3C TEKT2 FSD1 HOOK1 DCDC2 KIF11 DNAH8 GAS8 KIF3C DNAH11 TRPV4 PSRC1 INCENP KNSTRN NUSAP1 CDK1 DNAH6 KIF5A CENPJ BIRC5 CCT3 TTLL9 JAKMIP1 SCTR KIF19 SPAG6 KIF2A KIF7 DYNLL2 SPAG5 DNAH5 KLHL22 TUBG1 DNAH7 NINL TUBB2A TUBA3D KIF22 DNM1 TUBA8 KIF21A HID1 MAP6D1 KIF20B POLB CCT7 KLC2 KLC4 CKAP5 TUBG2 TTLL3 CDK5RAP2 DYNC1LI2 KIF21B EML6 TBCA CKAP2 DNAI2 HAUS6 DYNC2H1 FAM161A RAB3D KATNB1 SKAP1 TTLL6 HAUS4 APC2 NAV1 TUBGCP4 SYBU CCDC181 DNAH1 HOOK2 TUBA4B TPGS2 CDK5 TBCB BCAS3 CAMSAP3 CENPE MAP1LC3A SRPRB GOLGA2 TTC30B DCDC1 TUBA1C MAP9 DNM1L TTLL5 CLASP1 KIF24 MAP2K2 ROR2 DNAL4 SHROOM1 DYNC1H1 TEKT1 BAG2 GSK3A RUSC1 FAM110C PCNT TUBGCP2 KIFAP3 LZTS2 PARP4 RCC2 TPPP3 NDRG1 TMEM214 KIF6 TPPP LRPPRC REEP4 DYNLT1 CALM3 DNAH9 TUBGCP5 KIF3A STMN1 DCTN3 DNAL1 SKA3 SKA2	up	***
GO_HEART_VALVE_DEVELOPMENT	0.0031064	0.0477205	0.4317077	-0.3982432	-1.700907	54	SMAD6 BMP2 BMPR2 TGFBR2 PDE2A GATA3 RB1 ROCK2 SNAI1 ROCK1 ADAMTS9 TBX5 DCHS1 TGFB2 RBPJ NOTCH1	down	*
GO_ASTROCYTE_DIFFERENTIATION	0.0012527	0.0256458	0.4550599	-0.3791189	-1.700165	67	DAB1 TAL1 IL1B BMP2 C5AR1 CLCF1 GRN LAMC3 VIM ID2 TLR4 HES1 ID4 CNTF IL6 PSEN1 LAMB2 C1QA NOTCH1 IFNGR1 GPR37L1 FPR2 EPHA4 ADORA2A LDLR MAPK1 TREM2 S100A8 NOG	down	*
GO_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0000218	0.0011984	0.5756103	0.3641099	1.700150	237	HMGA2 FOXM1 CEP72 TICRR CHEK2 NEK2 CCNB1 CENPF STOX1 BRCA1 CDK4 BRSK1 GTSE1 DBF4B KIF14 CEP70 PLK1 AURKB CDC6 TPX2 CCNB2 CDC25A ORC1 DTL ZFYVE19 CDK5RAP3 DCTN2 HAUS5 CEP250 MELK HMMR BTRC SMARCD3 AURKA ODF2 SFI1 CLSPN CDC25C TOPBP1 CHEK1 PSMD4 PKMYT1 FBXL8 BLM MNAT1 SKP2 CDK1 CENPJ PSMB5 PSMC4 FGFR1OP CEP63 CEP192 TUBG1 NEK10 PSMA5 NINL PSME2 MTA3 AKAP8L FZR1 PSMD2 ATAD5 PPME1 CDC7 CKAP5 PSMB3 CHMP4C WNT10B CDK5RAP2 UIMC1 HAUS6 HAUS4 PSMB4 CEP152 ESRRB ALMS1 CCNA2	up	**
GO_SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX	0.0022622	0.0383137	0.4317077	0.4570122	1.699259	54	LSM5 GEMIN4 PRPF6 SNRPE EFTUD2 SNRPA CD2BP2 SNRPD1 LSM7 DDX23 LSM4 TXNL4A SF3A2 PRPF18 SNRPD2 TXNL4B USP39 PRPF31 SNRNP70 SNRNP200 ZMAT2 PRPF3 SNRPC SF3B2 SART1 SART3 LUC7L3	up	*
GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS	0.0000202	0.0011369	0.5756103	0.3640288	1.699168	234	HMGA2 DDX11 CDC45 CHEK2 CCNB1 PAGR1 STOX1 NDC80 BRCA1 CDK4 SMPD3 RACGAP1 E2F8 GTSE1 DBF4B KIF14 AURKB ECT2 ESPL1 CDC6 TFDP2 CDC25A DTL CDT1 RANBP1 CASP2 SMARCD3 KIF23 RHNO1 KIF3B MSX2 MAP10 AURKA TPR MSX1 POC1A CXCR5 CDCA5 GPSM2 CDC25C SOX4 EGFR MAD2L1 MDM2 PML CNOT3 STXBP4 NUSAP1 ANAPC5 CDK1 CENPJ E2F1 FEN1 EZH2 CNOT11 SPAG5 EGF RAB11FIP4 MTBP GIPC1 CCNE1 DLGAP5 CNOT2 MTA3 MYBBP1A PKP4 NUDT16 KIF20B ATAD5 CDC7 ANKRD31 SH2B1 CENPV	up	**
GO_NON_MOTILE_CILIUM_ASSEMBLY	0.0020402	0.0354635	0.4317077	0.4674579	1.697554	48	CEP89 RPGRIP1L MKS1 IFT122 CEP250 BBS1 CCDC13 POC1A IFT172 C2CD3 CENPJ VANGL2 IFT52	up	*
GO_CYTOKINE_RECEPTOR_BINDING	0.0000134	0.0008044	0.5933255	-0.3230976	-1.697502	184	SMAD6 CXCL3 CD300LF IL1A CXCL16 IL1B BMP2 CDH5 ENG CCL3L1 CCRL2 MYD88 TGFBR3 IL1RN TGFBR2 IL23A SH2B3 CLCF1 ADAM17 LIFR ITGA5 IFNK GATA3 TRAF6 NODAL IL10 CCL22 SDCBP TNFSF12 TNFSF15 SOCS2 TMBIM1 CCL3 CXCL2 CCL4 XCL2 SMAD7 INHBA TGFB2 CNTF IL6 BMP3 JAK1 PIK3R1 GRB2 OSM CXCL5	down	***
GO_CELLULAR_AMINO_ACID_BIOSYNTHETIC_PROCESS	0.0015902	0.0304054	0.4550599	0.4311940	1.697046	71	CPS1 GPT GPT2 BHMT PSPH NOXRED1 PHGDH ALDH18A1 PAH SHMT2 PYCR2 ASS1 CAD PLOD2 GOT2 OAT PSAT1 ASNS SLC1A3 NAGS NAT8L GAD1 PYCR1 MTHFD1 SEPHS1 BCAT2 FOLH1 DPYD ASL PLOD1 MTR SHMT1 MTRR PLOD3	up	*
GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_INVOLVED_IN_INFLAMMATORY_RESPONSE	0.0032423	0.0491885	0.4317077	-0.4002264	-1.696553	51	MYD88 APOD CD36 CLEC7A SIRPA GRN SLC7A2 MEFV TLR4 FCER1G PER1 IL17D SNAP23 APPL1 CHIA CD6	down	*
GO_REGULATION_OF_BLOOD_PRESSURE	0.0004350	0.0122118	0.4984931	-0.3376157	-1.696421	123	ACVRL1 HMOX1 ACE EDNRB PPARG EMP2 RAMP2 ADRA1D BMPR2 TBXA2R GAS6 CYP4A11 RHOA ATP2B1 ADRB1 ADRB2 CES1 PDE4D PTPRO PTAFR NPR3 ID2 PRCP SGK1 CTSZ ADRA1A NPR1 SUCNR1 CD34 GPR37L1 SLC4A5 MME CPA3	down	*
GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	0.0000000	0.0000000	0.9436322	-0.2742653	-1.695997	871	TNR FFAR4 SIGLEC11 SEMA6B AJAP1 SEMA3G GPR17 NLRC4 SEMA6A EREG ACP5 CD300LF IL17RB SASH1 FOXF1 SWAP70 FCN1 TEK EDNRB SCIMP SIGLEC16 PPARG ADTRP CD55 PGC WFDC1 IL1B FABP4 MNDA WNT4 THBD CDH5 FYN LPL LY86 SAMHD1 CLEC12B CAV1 CALCRL CDH13 MYD88 BMPR2 TBXA2R C5AR1 CLEC10A RBM14 S1PR1 HMGCR FGF10 MARCO CASP12 IL1RL1 CD9 GAS6 OTUD4 PSMD5 LAMP1 TGFBR2 SCARF1 TRIB1 RFTN1 IL23A FGR DNASE1L3 PDE2A APOD SEMA6D CD36 ANXA1 MIR146A MYOZ1 PLA2G7 SH2B3 CARD16 SEMA3B ADA FOXA2 ADAM17 CLEC7A TNIP3 HSPB1 ANXA5 RNF125 FOXP1 IFNK SERPINB9 GATA3 JAM3 SIRPA PLXNA4 RB1 TRAF6 NFE2L2 NDEL1 GRN CRK CRTAM WNT3A KANK2 UBE2D3 PDGFA CASP5 SLC7A2 IL10 DUSP3 BIRC2 PTPRO MEFV CASP1 BST1 SLC46A2 ZSWIM6 KLF4 PLAUR THBS1 CEBPA STX3 SOCS5 LY96 UBQLN1 CCL3 NFKB1 CDKN1A CADM1 NR1D2 PTPRC IRAK2 SELP HPSE CCL4 TLR4 PTGER3 SFTPD XCL2 FCER1G PER1 DUSP1 PLEK ZMPSTE24 OXSR1 UBASH3B PTGIS BACE1 AKIRIN1 KREMEN1 PIAS1 STK24 HCK NCKAP1L IL17D CNTF METAP1 IL6 MUC3A PDE6A CD160 CTSS PDE6B SOCS3 APPL1 SEC14L1 PSMA1 NOTCH1 ETS1 RAC2 CARD8 HSPA1B IFNGR1 JAK1 PTGER4 CCR7 ENPP4 DAPK2 PRKCE GPR183 OSM MALT1 RTN4R UNC13B PRKACA SUCNR1 CST7 PPM1F CD34 PLCG2 UBB PELI1 BCL6B CALM1 YTHDF3 PSMD12 ICAM2 PRKCG EPPK1 TREX1 CD74 CR1 PIK3AP1 SMPDL3B CCR4 TGFB1 AP1G1 CD1D CD6 TEC FPR2 YTHDF2 NLRP6 PIK3C3 CNOT7 CD81 KLRC4-KLRK1 CCR1 CLASP2 GPR18 GRK4 ADAM10 IFNLR1 SYT11 CCR6 FGF2 IL18 IL18RAP TFPI ARRB2 SEMA4A RTN4 TIAM1 CXCR4 EPHA4 TAB2 RIPK2 NLRP3 UBE2D1 HAVCR2 PSME4 CREBBP GRIN3A ICAM3 TLR10 SIN3A NFKBIA ADORA2A CTSC EDN1 PAK2 KLRK1 PTEN MTUS1 PRKG1 AIM2 FGFR1 RORA ITCH LDLR PSMD6 PSMD9 SFPQ IL16 PUM1	down	***
GO_FOCAL_ADHESION_ASSEMBLY	0.0008099	0.0190862	0.4772708	-0.3672649	-1.694854	77	ACVRL1 TEK DLC1 WNT4 CORO1C RHOA APOD SFRP1 ROCK2 DUSP3 SORBS1 LIMS1 ROCK1 THBS1 PEAK1 FAM107A MAP4K4 FERMT2 PPM1F EPHA3 TESK2 CLASP2 ACTN2 MACF1 EPB41L5 LIMCH1 PTEN IQGAP1	down	*
GO_METAL_CLUSTER_BINDING	0.0018928	0.0340704	0.4550599	0.4458842	1.694264	59	DDX11 PRIM2 POLE XDH CISD1 NDUFS2 BRIP1 ERCC2 TYW1 DNA2 UQCRFS1 NFS1 POLD1 NDUFS7 NDUFV1 CISD3 RTEL1 CDK5RAP1 NUBP2 RSAD1 NDUFS8 NUBPL CIAPIN1 CDKAL1 DPYD RSAD2 GLRX5	up	*
GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY	0.0003266	0.0096599	0.4984931	-0.3399375	-1.694012	120	RASIP1 HHEX IL1B INPP5K CAV1 HMGCR PRKAR1A HEG1 SH2B3 FBXO7 LATS2 HSPB1 HIPK3 PAQR3 RB1 SFRP1 SPRY2 MAPK8IP1 DUSP3 CEBPA CDKN1A MIR24-2 DUSP1 PKIG PPP2CA DNAJA1 DUSP8 IPO7 SPRY4 PKIA CHORDC1 DUSP5 MYOCD RGS2 KAT2B PP2D1 CDKN1C IPO5 PTEN DUSP7 SMPD1 CDKN1B DUSP6	down	**
GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION	0.0032492	0.0492185	0.4317077	0.5022943	1.693559	33	PARPBP TIMELESS POLQ FIGNL1 MAGEF1 TP53BP1 HELB CHEK1 RAD51AP1 RECQL5 PARP1 MAD2L2 UBQLN4 RTEL1 RAD51 SIRT6	up	*
GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY	0.0019922	0.0351383	0.4317077	-0.3606120	-1.693514	82	PHACTR1 DLC1 WNT4 GPR65 ARHGEF15 INPP5K BAG4 S1PR1 CDC42 RHOA RGCC SFRP1 SORBS3 ROCK2 ARRB1 SORBS1 ROCK1 SRF WASF2 ARHGEF10 PTGER4 PIK3R1 PPM1F WNT11 CLASP2 LIMCH1 CUL3 RAPGEF3 SYNPO2L	down	*
GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS	0.0000000	0.0000002	0.8012156	0.3358868	1.693112	711	HMGA2 TRIP13 TP63 DDX11 FOXM1 EGLN3 EYA1 RUVBL1 CDC45 TICRR PARPBP MCM10 FANCI CHEK2 EYA2 CCNB1 TIMELESS POLQ UBE2T PAGR1 CHCHD6 DDIT4 PIF1 BRCA1 BRSK1 E2F8 GTSE1 NPAS2 PMS2P5 POLE NABP2 PLK1 PTTG1 WDR70 TFDP2 FIGNL1 RBBP8 UHRF1 ACER2 MCM4 MCM2 RAD54B PMS2 XRCC2 DTL CIB1 MCM8 LIG3 MAP2K6 GINS4 SMUG1 MRPS35 CDK5RAP3 MAGEF1 IKBKE RUVBL2 CASP2 EXO1 NUDT1 CHAF1A C9orf116 TP53BP1 POLM RHNO1 FANCA CCDC13 BRAT1 EEF1E1 AUNIP TOP2A AURKA EME1 CBX3 REC8 ATR POLD2 IRF3 SMARCAL1 MCM7 ASCC2 MSX1 CLSPN SMYD2 MMS22L CDCA5 PRKDC TRRAP WDHD1 WNT1 HELB RAD54L FANCD2 MCM3 CHAF1B CDC25C SOX4 EGFR LIG1 EME2 MORC2 TOPBP1 CHEK1 NEK11 ACTL6A RAD51AP1 XRCC1 MDM2 PRMT6 MRPS11 BRIP1 RAD18 BLM PPP5C PML CNOT3 PLA2R1 ERCC2 MNAT1 STXBP4 RECQL5 DYRK2 PARP1 POLN CBX5 PAK1 ING4 CDK1 POLE2 RFWD3 ZNF652 EEPD1 E2F1 UNG DNA2 AP5Z1 NEIL3 FEN1 CNOT11 METTL3 OARD1 CBX1 MAD2L2 RECQL4 STK11 RNASEH2A POLR2H FANCG CEP63 INTS7 CDK3 DCLRE1C FANCF CNOT2 SPATA18 POLL MBD4 RAD9A MC1R KIF22 RAD51D SSRP1 COPS7B FBXO4 NFATC4 ESCO2 MGMT GINS2 FZR1 NUDT16 TCEA1 USP43 TRIM32 BCL2L12 POLD1 POLB ATAD5 PARP9 COPS6 SLX4 CDC7 RAD50 UBQLN4 SUPT16H PALB2 TWIST1 SIRT4 HMGA1 ASCC1 BCL2L1 RPA1 POLR2J BAD FANCM UBE2V2 MCM6 MGME1 THOC5 WRNIP1 PRMT1 XRCC4 MCM5 ANKRD1 TDP1 ZRANB3 UIMC1 NEK4 TFAP4 HMCES AATF POLR2I IGHMBP2 PMS2P1 MSH4 PMS1 MCRS1 MSH2 NFRKB DTX3L RTEL1 RFC5 WDR4 CEP164 INO80E RAD51 TNKS1BP1 EYA4 PAXIP1 NUDT16L1 WDR76 SIRT6 PNKP TONSL PARG BCL6 XPC MPG SWI5 TP53 NEIL1 APEX1 FBXO45 RAD1 E2F7 DDB2 MUC1 PIAS4 MRPS26 IMMP2L ACTR5 TMEM161A IFI16 TIPRL ERCC3 ALKBH2 PARP2 TTC5	up	***
GO_T_CELL_MEDIATED_IMMUNITY	0.0008092	0.0190862	0.4772708	-0.3644137	-1.693067	79	CD55 IL1B EMP2 CD1C SLC11A1 RFTN1 IL23A CD8A GATA3 IL18R1 TRAF6 FAM49B PTPRC PRF1 SMAD7 IL7R IL6 STX7 MALT1 TBX21 TREX1 CD1D ZBTB1 CD81 FCGRT ICAM1 IL18 IL18RAP NLRP3 CTSC CD1E	down	*
GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE	0.0000158	0.0009134	0.5756103	0.3565950	1.690548	281	HMGA2 TRIP13 BRINP1 TICRR CHEK2 BUB1B CCNB1 CENPF NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB PTTG1 CDC6 TFDP2 ORC1 ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 NLE1 KNTC1 BUB1 TOP2A AURKA EME1 TPR MAD1L1 CLSPN PRKDC TOM1L1 CDC25C SOX4 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 BLM PML CNOT3 PTPN3 CDKN2C CTDSP2 CDK1 RFWD3 E2F1 PSMB5 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 CNOT2 PSMA5 RAD9A PSME2	up	***
GO_TRANSFERASE_ACTIVITY_TRANSFERRING_SULFUR_CONTAINING_GROUPS	0.0018068	0.0332048	0.4550599	0.4580204	1.690309	53	SULT1C3 HS3ST1 CHST6 SULT1C2 CHST4 GAL3ST1 MOCOS HS3ST5 AMACR TST GAL3ST4 NFS1 CHST3 TRMU SULT1B1 CDK5RAP1 SULT1A3 OXCT1 CDKAL1 ACSM3 CTU2 MPST	up	*
GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	0.0023850	0.0397462	0.4317077	-0.3943279	-1.689352	56	TGFBR2 IL23A RHOA ANXA1 ADA HLX GATA3 SOCS5 SMAD7 NCKAP1L CD80 CD83 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 IL18 RIPK2 NLRP3 ZBTB16 HMGB1 RC3H2 IRF4 NFKBIZ CBFB PNP	down	*
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	0.0001155	0.0043351	0.5384341	0.3646507	1.688054	217	HMGA2 TRIP13 TICRR CHEK2 BUB1B CCNB1 CENPF NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 PLK1 AURKB CDC6 TFDP2 ORC1 DTL ZFYVE19 CDT1 CDK5RAP3 SPDL1 CASP2 BUB1 AURKA TPR MAD1L1 CLSPN PRKDC CDC25C SOX4 TOPBP1 CHEK1 MAD2L1 PSMD4 MDM2 BLM PML CNOT3 CDKN2C CTDSP2 CDK1 RFWD3 E2F1 PSMB5 EZH2 CNOT11 PSMC4 MAD2L2 KLHL22 CNOT2 PSMA5 PSME2 FZR1 PSMD2 PSMB3 CDC20 CHMP4C CDK5RAP2 PRMT1 UIMC1	up	**
GO_RESPONSE_TO_ESTROGEN	0.0026611	0.0430797	0.4317077	-0.3900599	-1.688009	59	SMAD6 ZNF366 HMOX1 TEK PPARG CAV1 CITED2 SFR1 TGFBR2 ARSB SERPINB9 ASH2L GATA3 SFRP1	down	*
GO_CHROMOSOME_ORGANIZATION	0.0000000	0.0000000	0.8753251	0.3312142	1.687251	927	HMGA2 TRIP13 TP63 DDX11 HELLS FOXA3 EYA1 DDX12P HJURP STAG3L2 RUVBL1 CDC45 BUB1B NUP107 NEK2 EYA2 CCNB1 SOX2 CENPF POLQ PAGR1 KIF18B NDC80 PRIM2 PIF1 BRCA1 TTK GINS1 RACGAP1 CABIN1 KIF14 L3MBTL1 TSPYL5 DNMT3B POLE NABP2 MSTO1 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 WDR70 ESPL1 CDC6 SOX9 UHRF1 MCM4 PRKCA MCM2 RAD54B PRC1 MSL3P1 CCT6A MCM8 MIS18A GINS4 SRPK1 RCCD1 NCAPD2 ZWINT CDT1 CCT2 SPDL1 TOP3B RUVBL2 SDR16C5 SMARCD3 EXO1 SMARCC1 KIF23 STAG3 CHAF1A FOXA1 MKI67 BOD1 HLTF BUB1 TOP2A MAP10 CCT5 CENPL GPER1 AURKA NUP155 CBX3 REC8 POLA2 SYCP2 ATR POLD2 TPR SMARCAL1 KIF2C MCM7 MAD1L1 CENPW SMYD2 TTLL12 CDCA5 PRKDC TRRAP BRPF3 HELB SETDB1 RAD54L FANCD2 MCM3 CHAF1B HORMAD1 YEATS2 CHD6 BRD9 MORC2 ZNHIT1 CHEK1 NEK11 ACTL6A MAD2L1 FBL CENPO XRCC1 PIH1D1 PRMT6 DSCC1 BRIP1 HSF4 BLM PPP5C PHB PML NAA40 TADA2A ERCC2 MNAT1 RECQL5 PARP1 PSRC1 INCENP KNSTRN NCAPG2 TERC NUSAP1 ASF1B PAK1 ANAPC5 ING4 CDK1 WDR5B SSBP1 POLE2 RFWD3 CENPH CCT3 SUN1 DIS3L2 ZMIZ2 NAV2 NPM3 NCAPG DNA2 FEN1 EZH2 SPAG5 TAF6 TRAPPC12 PRKAA2 MAD2L2 VPS72 KLHL22 RECQL4 CENPP TEP1 KPNB1 L3MBTL3 DNMT1 TELO2 CCNE1 PABPC1L CDC23 TUBG1 DCLRE1C DLGAP5 TRIM16 SATB2 SMG5 MRGBP TACC3 KIF22 HIRA RAD51D HMGN3 MTA3 TRIM37 SUDS3 COPS7B FBXO4 CHTF18 CENPQ AKAP8L HDAC1 ESCO2 GINS2 ANP32E NOC2L LRWD1 PRMT7 SAP30 ANAPC1 CHD5 KDM3B POLD1 ESR1 COPS6 SLX4 ZBTB7B CCT7 RAD50 KDM3A ANKRD31 CENPK BAZ2A TADA3 EP400 SUPT16H STAG3L4 CENPV MEI1 PPHLN1 L3MBTL2 BRD8 CDC20 CENPM YLPM1 TWIST1 TUBG2 HMGA1 ALKBH4 RPA1 CHMP4C PELO CDK5RAP2 MCM6 KDM4B DNMT3A CHTF8 CENPT PRMT1 MCM5 USP21 ZRANB3 UIMC1 PYGO2 NSD1 NFE2 KATNB1 IGHMBP2 PRKD2 SMARCC2 ZNF274 ATAD2 PRMT5 NUP62 MSH4 SUV39H2 MCRS1 MSH2 CCNA2 SMARCA4 NTMT1 PRIM1 DTX3L BANF1 RTEL1 RFC5 ZNF462 INO80E MLLT6 RAD51 HLCS TNKS1BP1 BRMS1 CHMP1A NOS1 EYA4 SUPT3H PAXIP1 CHMP2A CHD3 CDK5 SIRT6 SMC2 PNKP LIF BCL6 XPC MAU2 CENPE SRCAP TP53 KDM5B APEX1 NCAPD3 PWP1 SMARCB1 ATF7IP DDB2 RRS1 NAT10 MUC1 RCBTB1 ZFPM1 SART3 ACTR5 SS18L1 SETD5 ERCC3 NCAPH ACIN1 PCGF6 POGZ INO80B CHMP6 SETD1A PCGF2 MBTD1 MLH3 MAP3K12 SPHK2 TOP3A METTL4 DFFB DSN1 HDAC10 HR RBL1 FBXO5 LCMT1 HUWE1 SAFB NSL1 EXOSC10 MECOM SMYD3 NHP2 RAG1 NPM1 CHD8 RNF8 DCLRE1B MSH6 RNF40 HMG20B WDR5 DQX1	up	***
GO_CYTOKINE_BINDING	0.0010549	0.0229576	0.4550599	-0.3478924	-1.686643	106	ACVRL1 SOSTDC1 GREM2 ENG CCRL2 BMPR2 TGFBR3 IL1RL1 IL1RN TGFBR2 CD36 LTBP4 LIFR FZD4 IL18R1 CD93 TCAP THBS1 NRROS IL2RB IFNGR1 CCR7 ACKR3 CD74 CCR4 LRRC32 IFNAR1 CCR1 LTBP1 CCR6 CXCR4 CCR9 KIT LTBP3 NRP2 GREM1 GHR CX3CR1 ITGB1 ZFP36 CD109 NOG	down	*
GO_NUCLEOSIDE_METABOLIC_PROCESS	0.0009038	0.0206754	0.4772708	0.4129181	1.686456	87	AK4 PRTFDC1 GMPS UMPS DPYS NME1 DNPH1 DLG1 CARD11 NT5C1B NME9 NME5 AHCY CAD LRGUK UCK2 ATIC OARD1 UCKL1 UPP2 DHODH TK1 DTYMK NT5M APOBEC2 NME4 NME7 GMPR2 TK2 APOBEC3B DGUOK DPYD APRT OPA1 PRPSAP2 TYMP	up	*
GO_TRNA_BINDING	0.0029951	0.0469855	0.4317077	0.4619816	1.684843	49	SLFN13 METTL1 XPO5 XPOT AARS2 NSUN2 SARS2 EEFSEC DTD1 TRMU PUS1 YARS2 IARS2 NSUN6 IGHMBP2 FARSA CTU1 EARS2 MRPS27 DTD2	up	*
GO_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.0020234	0.0353681	0.4317077	-0.3819814	-1.684772	65	GPR17 EDNRB F2RL3 LHCGR P2RY1 GPR65 ADRA1D C5AR1 S1PR1 NMUR1 GPR4 NPR3 P2RY2 PTGER3 GNAQ GPR157 PTH1R HRH1 ADRA1A HOMER1 FPR2 ACTN2 GPR18 EDN1 LPAR6 C5AR2 CX3CR1 FPR1 FPR3 GPR55	down	*
GO_GOLGI_LUMEN	0.0028470	0.0451506	0.4317077	0.4319381	1.683404	68	MUC5B PCSK6 MUC13 HS3ST1 MUC4 MUC16 MUC5AC LHB PROC GPC2 MUC20 PROZ PODXL2 MUC6 WNT1 WNT5B PPIL2	up	*
GO_NUCLEOTIDYLTRANSFERASE_ACTIVITY	0.0013228	0.0265971	0.4550599	0.3974238	1.681860	108	POLQ PRIM2 NMNAT3 POLE FLAD1 TAMM41 POLR3A RPAP1 POLM POLA2 POLD2 COASY POLR3C POLN TERC CMAS POLE2 POLR3K POLR1C TEP1 NMNAT2 POLR2H POLL POLD1 POLB POLR2J GMPPA NMNAT1 POLR2J3 POLR2I POLR3E MAB21L1 PRIM1 POLR3B CTU1 POLR1B POLR1A GDPGP1 OAS3	up	*
GO_IMMUNOGLOBULIN_PRODUCTION	0.0002906	0.0089250	0.4984931	0.3848578	1.679704	130	IGLV4-69 IGLV3-27 IGKV3D-15 IGKV1-17 IGKV2D-29 IGLV1-36 IGKV3-15 POLQ IGKV1-6 IGKV1-16 GCNT3 IGKV1-27 PMS2P5 IGLV3-9 IGKV4-1 GPI PMS2 IGKV2D-28 IGLV3-10 EXO1 CARD11 TP53BP1 POLM IGLV1-44 PRKDC IGKV1-5 IGKV2-24 IGKV1D-33 IGLV1-40 IGKV1-9 UNG MAD2L2 IGLV7-43 IGLV6-57 POLL IGLV1-47 POLB ATAD5	up	**
GO_REGULATION_OF_CELL_ADHESION_MOLECULE_PRODUCTION	0.0030779	0.0477205	0.4317077	-0.9362989	-1.678616	3	IL1B CAV1	down	*
GO_LEUKOCYTE_MEDIATED_CYTOTOXICITY	0.0024096	0.0399647	0.4317077	-0.3658278	-1.677636	76	EMP2 CLEC12B CD1C LAMP1 IL23A DNASE1L3 SERPINB9 CRK CRTAM FAM49B CADM1 PTPRC PRF1 IL7R CD160 TYROBP STX7 AP1G1 CD1D KLRC4-KLRK1 FCGRT UNC13D ICAM1 IL18 IL18RAP ARRB2 HAVCR2 CTSC CD1E KLRK1 LYST	down	*
GO_MALE_GAMETE_GENERATION	0.0000039	0.0002887	0.6105269	0.3478826	1.677513	344	TSPAN8 TRIP13 TP63 SPATA24 SPATA25 MYCBPAP FOXA3 RUVBL1 PMFBP1 CCNB1 WFDC2 DPY19L2P1 GAL3ST1 CREB3L4 RACGAP1 CATSPERB SLC26A8 ASPM TTC26 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 SPINK1 CIB1 TDRKH MCM8 SRPK1 RSPH1 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA REC8 ODF2 SYCP2 POC1A DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 HORMAD1 CDC25C NME5 OAZ3 HSF2BP BRIP1 SPAG8 CCDC136 MEA1 ASF1B LRGUK MERTK SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 GOLGA3 FANCG CATSPERG CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 CTSV MNS1 ADAM28 IQCG MORN2 PCSK4 TSSK3 SPA17 SPATA32 SLC4A2 CHD5 TYRO3 KDM3A MEI1 ROPN1B BCL2L1 CATSPER2 BAD DNMT3A RAI14 GGT3P DPY19L2 PYGO2 GGT5 PHC2 PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1	up	***
GO_ALPHA_BETA_T_CELL_DIFFERENTIATION	0.0009749	0.0218086	0.4772708	-0.3528474	-1.677042	91	SPN TGFBR2 IL23A RHOA ANXA1 ADA FOXP1 HLX GATA3 IL18R1 FUT7 SOCS5 SMAD7 NCKAP1L CD80 IL6 PTGER4 CD83 GPR183 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 GPR18 IL18 SEMA4A RIPK2 NLRP3 RORA ZBTB16 TNFSF8 HMGB1 IRF1 RC3H2 IRF4 NFKBIZ CBFB PNP	down	*
GO_TUBE_MORPHOGENESIS	0.0000000	0.0000000	0.8634154	-0.2761148	-1.676857	707	TRIM71 ANGPT4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SOSTDC1 SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK DLC1 TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB BMP2 CDH5 ENG FOLR1 ECSCR SOX17 CAV1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 HSPG2 HEG1 RHOA ZEB2 APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM WNT2B RAP1A ITGA5 CLEC14A HSPB1 LUZP1 FZD4 FOXP1 ANPEP HLX GATA3 NR4A1 JAM3 RGCC TRAF6 NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A ZEB1 SPI1 TCAP MTHFR PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 ROCK2 AMOTL1 NRARP TBX4 NPNT TNFSF12 TSPAN12 KLF4 ROCK1 VASP THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HPSE ID2 MIR24-2 RECK PIK3C2A ELK3 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS DCHS1 HES1 PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ GZF1 HESX1 FLT1 AREG IL6 WASF2 PKNOX1 CD160 PSEN1 NDNF JUN NOTCH1 ETS1 CTSZ JUNB JAK1 RHOJ PODXL	down	***
GO_ALPHA_BETA_T_CELL_ACTIVATION	0.0005523	0.0147139	0.4772708	-0.3359668	-1.676568	119	CD55 SPN TGFBR2 IL23A RHOA ANXA1 ADA FOXP1 HLX GATA3 IL18R1 MAPK8IP1 FUT7 SOCS5 PTPRC SMAD7 NCKAP1L CD80 IL6 CD160 PTGER4 CD83 GPR183 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 CD81 GPR18 IL18 SEMA4A RIPK2 NLRP3 ADORA2A RORA ZBTB16 TNFSF8 HMGB1 CD3E IRF1 RC3H2 IRF4 NFKBIZ EBI3 CBFB PNP	down	*
GO_MYELOID_CELL_HOMEOSTASIS	0.0002920	0.0089387	0.4984931	-0.3328857	-1.675910	127	EPAS1 HMOX1 TAL1 KLF13 GATA2 HCAR2 TMOD3 TGFBR3 ANXA1 SH2B3 ADAM17 SLC7A11 GATA3 JAM3 RB1 SPI1 MPL AXL ID2 FCER1G LYAR INHBA ADD1 SRF NCKAP1L IL6 PKNOX1 ETS1 HSPA1B DNASE2 SP3 KLF2 FOXO3 EPB42 JMJD6	down	**
GO_CHROMOSOME_LOCALIZATION	0.0022848	0.0385260	0.4317077	0.4347116	1.674486	65	SPICE1 CCNB1 CENPF NDC80 KIF14 NUF2 CDCA8 CDT1 SPDL1 BOD1 KIF2C MAD1L1 CDCA5 PSRC1 SUN1 SPAG5 TRAPPC12 KPNB1 CDC23 DLGAP5 KIF22 CENPQ MEI1 CHMP4C KATNB1 NUP62 CHMP1A CHMP2A CENPE RRS1 CHMP6 DYNC1H1	up	*
GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS	0.0006620	0.0165651	0.4772708	0.3847898	1.673566	127	HKDC1 ENTPD2 AK4 NUP107 PGM2L1 DDIT4 GPI GAPDH ALDOC AK8 NME1 DLG1 CARD11 NUP155 TPR NME9 PKM NME5 PFKP ALDOA ENTPD5 GCKR LRGUK ALDOB BPGM NUP205 AK7 PRKAA2 EIF6 FOXK1 DTYMK NUDT16 NUP85 DHTKD1 ENTPD8 AAAS ENTPD3 BAD PFKFB4 ESRRB NUP62 NME4 HK2 SEC13 PFKM NME7 PGAM1 SIRT6 ENO1 NUP210 NUP93 PRKAG1	up	*
GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION	0.0012671	0.0258884	0.4550599	-0.3568496	-1.672876	85	ACVRL1 HMOX1 TEK GATA2 BMP2 CDH13 BMPR2 MIR27B MIR146A ADAM17 CAV2 NR4A1 AKT3 IL10 STAT5A NRARP TNFSF12	down	*
GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION	0.0000043	0.0003085	0.6105269	-0.2927877	-1.670684	294	SIRPB1 CD55 GATA2 IL1B FYN CAV1 FGF10 CDC42 IL1RL1 GAS6 LAMP1 TGFBR2 IL23A FGR RHOA ANXA1 CLCF1 CD5 ADA CLEC7A MAP3K8 HLX GATA3 SIRPA TRAF6 WNT3A TFRC ZMIZ1 IL10 BST1 PTAFR THBS1 CEBPA CLECL1 SOCS5 MPL FAM49B CCL3 CDKN1A PTPRC SELP AXL TLR4 IGFBP2 FCER1G PLEK IL7R HES1 NCKAP1L CD80 IL6 CD160 TYROBP CCR7 PIK3R1 CD83 GRB2 GPR183 MALT1 RPS6KA1 DOCK8 AP3B1 TBX21 PELI1 TNFSF13 RUNX3 CD74 TGFB1 VAV3 AP1G1 CD1D ZBTB1 CD6 CD86 IRS2 PDCD1 CD81 KLRC4-KLRK1 IGHV3-23	down	***
GO_MUSCLE_CELL_PROLIFERATION	0.0000700	0.0029320	0.5384341	-0.3193618	-1.670474	169	RBP4 EREG HMOX1 PPARG CALCRL CDH13 S1PR1 HMGCR PRKAR1A MIR27B TGFBR3 TGFBR2 TRIB1 APOD TBX2 HBEGF FOXP1 TRAF6 TCF7L2 FOXC2 CNN1 IL10 PTGIR PTAFR KLF4 THBS1 NPR3 ABCC4 CDKN1A ID2 TBX5 GNAI2 MIR17HG AKIRIN1 TGFB2 RBPJ IL6 JUN NOTCH1 NPR1 SAV1 PIM1 SOD2 MEIS1 NQO2 MYOCD GATA6 RXRA FGF2 IL18 SF1 EDN1 FOXJ2 PTEN PRKG1 FGFR1 MIR548C ZFPM2	down	**
GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY	0.0030955	0.0477205	0.4317077	-0.3897297	-1.669652	56	CLEC12B CD1C LAMP1 IL23A DNASE1L3 SERPINB9 CRK CRTAM FAM49B CADM1 PTPRC IL7R CD160 TYROBP STX7 AP1G1 CD1D KLRC4-KLRK1 FCGRT ICAM1 IL18RAP ARRB2 HAVCR2 CD1E KLRK1	down	*
GO_POSITIVE_REGULATION_OF_LOCOMOTION	0.0000000	0.0000033	0.7337620	-0.2837412	-1.669469	483	ANGPT4 SEMA6B SEMA3G SEMA6A SASH1 FOXF1 HMOX1 SWAP70 TEK CXCL16 PECAM1 GLIPR2 GATA2 SPN IL1B RDX RAPGEF2 BMP2 CDH5 BAG4 CAV1 MYADM CDH13 BMPR2 C5AR1 S1PR1 FGF10 MIR27B NEDD9 VAPA GAS6 TGFBR2 IL23A FGR RHOA NUMB SEMA6D ANXA1 MIR146A PLA2G7 SEMA3B HBEGF ADAM17 CLEC7A ITGA5 HSPB1 FOXP1 CAV2 GATA3 PPP3CA NFE2L2 GRN CRK AKT3 SPRY2 ARHGEF2 PDGFA FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 SNAI1 SDCBP TACR2 PTAFR DAB2 THBS1 STX3 SPAG9 CCL3 SSH1 ITGAX PTPRC SELP CCL4 JAM2 XCL2 PIK3C2A OXSR1 NUS1 GNAI2 RUFY3 ANXA3 AKIRIN1 MAPRE2 TGFB2 SRGAP2C NCKAP1L MYO1C FAM107A SLC8A1 FLT1 IL6 JUN NOTCH1 ETS1 RAC2 MAP4K4 ELP5 DUOX1 RHOJ PODXL CCR7 DAPK2 PIK3R1 ACKR3 PRKCE DOCK8 SUCNR1 PPM1F MCAM PLCG2 CD151 PTP4A1 CD74 WNT11 CCR4 TGFB1 FPR2 MIR23A MIA3 IRS2 SOD2 LGALS3 CCR1 CLASP2 PLAA SPOCK2 ADAM10 CCL20 CCR6 ICAM1 FGF2 EPB41L5 CHMP3 SEMA4A RTN4 IQSEC1 TIAM1 CXCR4 VPS4B	down	***
GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	0.0015753	0.0302342	0.4550599	-0.3601548	-1.669465	78	IL1B CD1C LAMP1 IL23A CLCF1 GATA3 IL18R1 TRAF6 CRTAM TFRC FAM49B CADM1 PTPRC FCER1G IL6 CD160 STX7 MALT1 TBX21 TNFSF13 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT IL18 IL18RAP NLRP3 CD1E KLRK1	down	*
GO_DEOXYRIBONUCLEASE_ACTIVITY	0.0024869	0.0409134	0.4317077	0.4541548	1.668813	52	POLE RBBP8 NME1 EXO1 EME1 EME2 XRCC1 DNA2 FEN1 DCLRE1C MBD4 RAD9A POLD1 SLX4 DNASE1 RAD50 MGME1 ZRANB3 APEX1 RAD1 MUS81 DNASE1L2 DFFB RAG1 DCLRE1B DCLRE1A	up	*
GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS	0.0000000	0.0000000	0.9545416	-0.2682157	-1.667699	932	SLC6A4 TNR FFAR4 SMAD6 LIMS2 ANGPT4 DAB1 RBP4 SEMA6B RAB11FIP1 SEMA3G SEMA6A ACP5 ACVRL1 NOVA2 SOSTDC1 HMOX1 TEK EDNRB DENND5A TAL1 KLF13 PPARG ADTRP HHEX GATA2 IL1B TIE1 WNT4 RAPGEF2 THBD BMP2 PCSK9 FIG4 ARHGEF15 ECSCR SOX17 DDX6 CORO1C CALCRL BMPR2 GTF2I CTDSP1 TBXA2R HMGCR MIR27B IL1RL1 CD9 GAS6 SLC11A1 TGFBR2 NFATC3 TRIB1 LILRB3 IL23A HSPG2 RHOA APOD SEMA6D ANXA1 TBX2 WWC2 MIR146A MMRN2 ATP2B1 SH2B3 FBXO7 ASAP1 PTPRM CARD16 SEMA3B ADA CD33 FOXA2 ADAM17 LMNA ANXA5 RNF125 PAQR3 HLX ADIPOR1 ABHD6 EIF4E ADRB1 GATA3 PPP3CA SIRPA RB1 RGCC ADRB2 IL18R1 NFE2L2 GRN SFRP1 SPRY2 WNT3A SRGN ARHGEF2 PDE4D ZNF365 APOC1 PDGFA FOXC2 NODAL CST3 LRP4 GPR4 IL10 ROCK2 ARRB1 SNAI1 NRARP FOXO1 KCNMA1 PTPRO MEFV TRIM46 DAAM2 TACR2 YBX3 KLF4 PLAUR REST ZNF423 ID3 ROCK1 THBS1 ARNTL ADAMTS9 SOCS2 CLDN5 SOCS5 KLF7 NPR3 CCL3 NFKB1 PDE3B PTPRC VIM AXL ID2 TLR4 MIR24-2 PTGER3 SFTPD SMAD7 INHBA TBX5 ZNF706 UBASH3B PAFAH1B1 GNAI2 RUFY3 HES1 MIR17HG AKIRIN1 KREMEN1 ARHGDIB TGFB2 GNRH1 PROCR SRF SRGAP2C NCKAP1L KANK1 MYLIP RBPJ WNT9A IL17D ID4 CNTF PPP2CA AREG IL6 CD160 PSEN1 HPGDS NOTCH1 LIMD1 GABPA CUL4A CTSZ ADRA1A PDE5A CARD8 CNTN4 TYROBP IFNGR1 PTGER4 BAG5 IFRD1 PIK3R1 CD83 LSM1 NPR1 RC3H1 RTN4R REL PRKACA TRAK2 FSTL3 TBX21 TIGIT IP6K1 CD34 GPR37L1 KLF2 RUNX3 SRSF6 EPPK1 CD74 WNT11 SAV1 TGFB1 ISM1 SERPINB1 MTMR2 LRRC32 PDCD1 GLRA1 MEIS1 MYOCD CCR1 TOB1 NPTN CRY1 GATA6 N4BP2L2 RGS2 GPR18 PDE4B TSPO SYT11 LDLRAD4 FGF2 PCM1 VASH1 TFPI EPN2 ARRB2 OSR1 SEMA4A RTN4 EPHA4 NLRP3 TOB2 DIXDC1 PTCH1 SP100 HAVCR2 EPHA2 ULK2 STK4 NFKBIA CTSC EDN1 FOXJ2 PTEN SKI LTBP3 PRKG1 GPR171 FGFR1 ITCH LDLR DOCK4 NRG1	down	***
GO_DNA_METABOLIC_PROCESS	0.0000000	0.0000004	0.7881868	0.3301826	1.666505	736	HMGA2 TRIP13 DDX11 FOXM1 HELLS EYA1 RUVBL1 CDC45 TICRR PARPBP MCM10 FANCI CHEK2 NEK2 EYA2 CENPF TIMELESS POLQ UBE2T PAGR1 STOX1 MND1 PRIM2 PIF1 BRCA1 GINS1 SMPD3 NPAS2 DNMT3B PMS2P5 POLE NABP2 AURKB PTTG1 WDR70 CDC6 FIGNL1 RBBP8 UHRF1 MCM4 MCM2 RAD54B TYMS PMS2 XRCC2 ORC1 DTL CIB1 TDRKH CCT6A MCM8 LIG3 MIS18A GINS4 SMUG1 CDT1 CCT2 MAGEF1 NME1 TOP3B RUVBL2 EXO1 NUDT1 CHAF1A TP53BP1 POLM RHNO1 FANCA AUNIP TOP2A CCT5 GPER1 EME1 REC8 POLA2 ATR POLD2 SMARCAL1 MCM7 ASCC2 CLSPN MMS22L CDCA5 PRKDC TRRAP WDHD1 HELB RAD54L FANCD2 MCM3 CHAF1B EGFR LIG1 EME2 TOPBP1 CHEK1 ORC6 ACTL6A RAD51AP1 DCTPP1 XRCC1 THAP10 PRMT6 DSCC1 BRIP1 RAD18 BLM GRHL2 PPP5C PHB PML ERCC2 MNAT1 RECQL5 PARP1 POLN TERC CDK1 POLE2 RFWD3 PICK1 CCT3 EEPD1 UNG DNA2 AP5Z1 NEIL3 FEN1 EZH2 MAD2L2 RECQL4 TEP1 RNASEH2A KPNB1 POLR2H DNMT1 FANCG TELO2 CCNE1 DCLRE1C SMG5 FANCF POLL MBD4 RAD9A MC1R LONP1 KIF22 RAD51D SSRP1 COPS7B FBXO4 TK1 CHTF18 ESCO2 MGMT GINS2 FZR1 NUDT16 TCEA1 USP43 LRWD1 PRMT7 KRBA2 POLD1 POLB ATAD5 PARP9 COPS6 SLX4 CCT7 CDC7 DNASE1 RAD50 ANKRD31 BAZ2A KLHDC3 SH2B1 UBQLN4 SUPT16H PGBD5 PALB2 YLPM1 TWIST1 HMGA1 ASCC1 ALKBH4 RPA1 POLR2J FANCM UBE2V2 MCM6 MGME1 DNMT3A CHTF8 WRNIP1 XRCC4 MCM5 NMNAT1 ANKRD1 TDP1 ZRANB3 UIMC1 GINS3 EXOSC5 POLR2I IGHMBP2 PRKD2 PRMT5 PMS2P1 MSH4 PMS1 MCRS1 APOBEC2 MSH2 PRIM1 ZNF93 NFRKB DTX3L BANF1 RTEL1 RFC5 STAT6 CEP164 INO80E RAD51 N6AMT1 TNKS1BP1 ST20 EYA4 PAXIP1 NUDT16L1 SIRT6 PNKP TONSL PARG BCL6 XPC ZNF91 TCF3 MPG SWI5 TP53 NEIL1 APEX1 PPIA RAD1 SMARCB1 ATF7IP DDB2 NAT10 PIAS4 HGF TK2 HEMK1 ACTR5 TMEM161A ERCC3 ALKBH2 PARP2 TTC5 APOBEC3B INO80B MUS81 DNASE1L2 SPIDR MLH3 TOP3A METTL4 C11orf80 GSK3A DFFB PRPF19 HDAC10 MYO18A HUWE1 ATRIP EXOSC10 CDC34 NHP2 RAG1 NPM1 RNF8 BATF PIWIL4 PARP4 DCLRE1B TEFM MSH6 MTRR DCLRE1A ASCC3 EHMT1 POT1 ZSWIM7 HERC2 RMI1 LOX XRCC5 ETAA1 TIPIN	up	***
GO_R2TP_COMPLEX	0.0024983	0.0410329	0.4317077	0.9018703	1.663197	4	RUVBL1 RUVBL2 PIH1D1	up	*
GO_REGULATION_OF_NUCLEAR_DIVISION	0.0002494	0.0079967	0.4984931	0.3707196	1.662799	162	TRIP13 BUB1B NEK2 CCNB1 CENPF NDC80 TTK SMPD3 L3MBTL1 ANLN PLK1 AURKB PTTG1 ESPL1 CDC6 CDT1 SPDL1 RANBP1 MKI67 CUL9 CUL7 FBXO43 KNTC1 BUB1 MSX2 AURKA TPR MAD1L1 MSX1 CDCA5 TOM1L1 KIF11 HORMAD1 CDC25C CHEK1 MAD2L1 PKMYT1 NUSAP1 ANAPC5 CEP97 EGF MTBP MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 FZR1 KIF20B ANAPC1 CDK13 SH2B1 CDC20 CHMP4C CDK5RAP2 RCC1 PRMT5 NUP62 CEP85 CHMP1A CHMP2A AURKAIP1 LIF CENPE UBE2C MAP9 RAD1	up	**
GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER	0.0004072	0.0115266	0.4984931	-0.3209379	-1.661927	145	RAMP3 AKAP5 LHCGR ADCY9 P2RY1 GPR65 ADCY4 RAPGEF2 RAMP2 CALCRL ADRA1D TBXA2R S1PR1 RXFP1 MARCO PDE2A ANXA1 SSTR1 ADRB1 ADRB2 PDE4D PTGIR GRK5 NPR3 PTGER3 GNAQ GNAI2 PTH1R S1PR4 ADCY2 WASF2 HRH1 ADRA1A PALM PTGER4 PTGER2 GPR37L1 GPR3 FPR2 GNAI1 CCR1 GNA13 RGS2	down	*
GO_INTERFERON_GAMMA_PRODUCTION	0.0010303	0.0226990	0.4550599	-0.3509724	-1.658135	86	SPN IL1B IL1RL1 GAS6 SLC11A1 IL23A CLEC7A GATA3 SIRPA IL18R1 PDE4D IL10 FAM49B AXL TLR4 MIR24-2 INHBA CD160 CCR7 IRF8 AZI2 KLRC4-KLRK1 PDE4B IL18 IL18RAP RIPK2 HAVCR2 KLRK1	down	*
GO_MONOSACCHARIDE_CATABOLIC_PROCESS	0.0027712	0.0441560	0.4317077	0.4511265	1.657685	52	FUT6 XYLB PGM2L1 SORD GPI GAPDH ALDOC PKM PFKP KHK FUT2 ALDOA ALDOB BPGM FOXK1 GALK2 BAD HK2 PFKM PGAM1 GLYCTK TP53 FUT10 ENO1	up	*
GO_VACUOLE	0.0000000	0.0000002	0.8012156	-0.2749623	-1.657646	633	ACP5 RAMP3 SIDT2 PEBP4 MCOLN1 ACE TMEM150B IL1B MNDA CAT RAB44 SPNS1 LIPA RAMP2 THBD GPC5 PCSK9 CTSW CALCRL TMEM138 CHIT1 CYB5R3 ARL8B SLC15A3 CDC42 MANBA NCF2 CD1C VAPA FUCA1 LAMP1 CBL SLC11A1 HSPG2 ANXA1 SLC44A2 DNAJC3 MAN2B1 RRAGC SLC3A1 ADA RILP ARSB PCYOX1 ASAH1 NAAA GM2A IFI30 PRELP LITAF CYB561A3 ANPEP CLN5 ABHD6 STOM ADRB2 GRN LAMTOR3 SRGN ATP6V1H RAB14 ATP6V1B2 CYBRD1 FABP5 ARRB1 RAB12 PPT1 AHNAK SDCBP MEFV PEG3 SLC12A4 CDIP1 DAB2 GAA DRAM1 MAP1LC3B STX3 ATP6V1D TPP1 PLBD1 SPAG9 UBQLN1 CTSD TMBIM1 LAPTM5 CTBS C9orf72 HPSE ATP6V0D2 M6PR SFTPD TM6SF1 PRF1 WDR48 GCA HTT GNAQ HLA-DQA1 NRBF2 BACE1 LMBRD1 CMTM6 PI4K2A ACTR2 GLB1 HEXB HCK HGSNAT TBC1D5 PRCP TMEM9B CTSS GABARAPL2 PSEN1 SNAP23 VAT1 SFTPB CTSZ ATP6V0B ATP11A OSTM1 DNASE2 VPS26A TBC1D12 SNX2 STX7 GLIPR1 DAPK2 IDS ENTPD4 SNX1 CAP1 AP3B1 UVRAG CLN3 CST7 CD34 TMEM192 SLC3A2 ATP6V0D1 CD164 NAPG CD74 SORT1 AP1G1 CD1D MILR1 VAMP4 SBF2 MTMR2 TMEM230 GNAI1 ATP6V1A IFNAR1 PIK3C3 GALC ATP6V0C GNB4 GABARAPL1 ORM2 BRI3 VPS39 MFSD12 CLCN6 PLA2G15 IST1 SYT11 UNC13D CPQ LAT BLOC1S2 PIP4K2A CXCR4 HSP90AA1 CALCOCO2 GIMAP5 HSPA8 NHLRC3 KIT CTSC CD1E SNAP29 MMD ANXA11 LDLR CREG1 WDFY3 RNF13 RAB2A LYZ SMPD1 FNBP1 ZFYVE26 EPG5 ATP6V0A1 USP4 CTSH SPPL2A TMEM30A KCNE1 ATP11B LNPEP MAPK1 FTL SH3GLB1 NCF1 RB1CC1 RAB37 ZFYVE1 DRAM2 FPR1 SLC26A11 NFAM1 PIK3CG YWHAB VPS36 WDR41 LAMP3 SNX14 HLA-DRB1 LAMTOR5	down	***
GO_PYRIMIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	0.0016981	0.0316924	0.4550599	0.4100057	1.656828	83	CPS1 GPAT2 THTPA TYMS UMPS SMUG1 DPYS TAMM41 NME1 NME9 NME5 DCTPP1 CAD UCK2 UNG ENPP3 UCKL1 UPP2 MTOR MBD4 DHODH TK1 DTYMK AGPAT5 LCLAT1 NT5M	up	*
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS	0.0000150	0.0008855	0.5933255	0.3490474	1.656200	285	HMGA2 TRIP13 MDM1 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 PLK1 AURKB PTTG1 ESPL1 CDC6 TFDP2 RBBP8 ORC1 CCNF DTL ZFYVE19 CDT1 CDK5RAP3 SPDL1 CASP2 FBXO43 BUB1 GPER1 AURKA CBX3 TPR MAD1L1 CLSPN RRM2 PRKDC TOM1L1 HORMAD1 CDC25C SOX4 TOPBP1 CHEK1 MAD2L1 PSMD4 MDM2 MGA BLM PML CNOT3 CDKN2C CBX5 CTDSP2 CDK1 RFWD3 E2F1 PSMB5 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 CNOT2 PSMA5 PSME2 TRIM37 FZR1 PSMD2 CDC7 L3MBTL2 PSMB3 CDC20 CHMP4C CDK5RAP2 PRMT1 UIMC1 TFAP4	up	***
GO_ENDOTHELIAL_CELL_PROLIFERATION	0.0003708	0.0107502	0.4984931	-0.3310079	-1.655236	125	ACVRL1 HMOX1 TEK PPARG GATA2 BMPER BMP2 CAV1 CDH13 BMPR2 MIR27B MIR146A PTPRM ADAM17 CAV2 NR4A1 RGCC AKT3 IL10 STAT5A NRARP TNFSF12 THBS1 MIR24-2	down	*
GO_REGULATION_OF_CELL_ADHESION	0.0000000	0.0000006	0.7749390	-0.2757288	-1.654239	579	TNR SIRPB1 LIMS2 DAB1 AJAP1 SEMA6A ACVRL1 FOXF1 SWAP70 TEK DLC1 CCM2L ADTRP CD55 SPN IL1B ATXN3 WNT4 LPXN EMP2 RDX BMP2 FYN CD44 BAG4 CAV1 CORO1C MYADM CITED2 CDH13 S1PR1 PRKAR1A CDC42 MIR27B NEDD9 CD9 IL1RN TGFBR2 IL23A RHOA APOD CD36 ANXA1 MIR146A SH2B3 CD5 ADA FOXA2 PLXNA2 ITGA5 MAP3K8 FZD4 HLX PAG1 GATA3 PPP3CA JAM3 SIRPA PLXNA4 RGCC TRAF6 CRK SFRP1 WNT3A TFRC FOXC2 NODAL ZMIZ1 IL10 ROCK2 NRARP DUSP3 NPNT PTPRO DENND6A LIMS1 BST1 PTAFR KLF4 ROCK1 THBS1 STX3 CLECL1 SOCS5 FAM49B PDE3B PTPRC JAM2 IGFBP2 SFTPD DUSP1 SMAD7 PEAK1 IL7R UBASH3B HES1 ARHGDIB TGFB2 GNRH1 SRF NCKAP1L NINJ1 KANK1 FAM107A CD80 PPP2CA IL6 CD160 UTRN NDNF NOTCH1 ETS1 PDE5A RAC2 MAP4K4 PODXL CCR7 PIK3R1 CD83 PRKCE GRB2 MALT1 RC3H1 HSD17B12 DOCK8 AP3B1 FSTL3 TBX21 TIGIT PPM1F PELI1 CD164 MBP RUNX3 CD74 EPHA3 TGFB1 VAV3 CD1D ZBTB1 CD6 YTHDF2 LRRC32 MIA3 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1 CLASP2 MACF1 SPOCK2 ADAM10 ABI3BP UNC13D ICAM1 IL18 ABL2 ARPC2 EPB41L5 CXCR4 DACT2 RIPK2 NLRP3 HAVCR2 EPHA2 RND1 LIMCH1 RET ADORA2A PAK2 KLRK1 PTEN PRKG1 CYTH1 TNFSF9	down	***
GO_MICROTUBULE_CYTOSKELETON	0.0000000	0.0000000	0.8634154	0.3232849	1.653758	1015	KIF1A CCNO SAA1 PKHD1 KIF12 KLC3 DDX11 CEP72 SPICE1 KIF20A MDM1 RUVBL1 CEP89 CDC45 DNAH2 RPGRIP1L BUB1B NEK2 ZNF12 CCNB1 CENPF STOX1 KIF18B NUDCD3 NDC80 MKS1 CCDC113 BRCA1 FANK1 TUBB2B TTK RACGAP1 BRSK1 GTSE1 IFT122 KIF14 SPAG17 CCDC14 CNTD2 ASPM STIL TTC26 CEP70 PLK1 IFT27 CDCA8 AURKB ECT2 ESPL1 CDC6 TPX2 GAPDH TFDP2 CCNB2 MCM2 DNAH3 PLEKHA7 PRC1 XRCC2 CCNF DTL DYNC1I1 CIB1 HNF4G CCT6A ZFYVE19 KIF27 SHMT2 CDK5RAP3 DNAH14 CCT2 DCTN2 SPDL1 WDR90 SPPL2B NME1 MICALL2 DNAI1 HAUS5 RANBP1 CEP250 WDR62 RSPH1 TTLL4 RUVBL2 HMMR DLG1 MAP7 KIF23 CEP55 BBS1 BOD1 CUL7 BICD1 KIF15 KNTC1 TSGA10 KIF3B CCDC13 CCDC77 AUNIP TOP2A FBF1 MAP10 CCT5 AURKA CBX3 ODF2 SFI1 IFT43 TPR SNCG KIF2C MAD1L1 POC1A AGBL4 WDR78 MPHOSPH9 TTLL12 MAP1LC3C TEKT2 FSD1 NSUN2 HOOK1 CCDC114 DCDC2 WDR73 KIF11 GPSM2 MCM3 YEATS2 WDR60 DNAH8 TOPBP1 CHEK1 NEK11 IFT172 CC2D1A MAD2L1 CKAP2L GAS8 KIF3C CBY1 TMEM63A DNAH11 SPAG8 RAD18 FNTB RABEP2 LRRC45 C2CD3 ERCC2 TRPV4 C4orf47 DLG5 PSRC1 INCENP MARK1 CCDC78 KNSTRN TTBK1 DRC1 NUSAP1 KRT18 LRGUK IQCB1 CDK1 CROCC DNAH6 CCDC61 CEP97 KIF5A SNX4 CENPJ DIDO1 BIRC5 CCT3 TTLL9 KIAA0753 JAKMIP1 POC5 E2F1 SCTR PSMB5 KIF19 ALDOB SPAG6 KIF2A ANKRD26 KIF7 SSX2IP CCDC88C DYNLL2 SPAG5 TTC23L POC1B RAB11FIP4 TRAF5 LCA5 DNAH5 CBX1 KCTD1 MAD2L2 KLHL22 FGFR1OP IFT52 RANGAP1 MZT2A MZT2B CEP63 BBS5 CCNE1 CEP192 EXOC7 TUBG1 DLGAP5 VPS41 DNAH7 NINL TACC3 CCDC151 TUBB2A TUBA3D KIF22 RAD51D IQCG DNM1 TUBA8 KIF21A CCDC146 HID1 PKP4 CLTA MAP6D1 KIF20B TEKT3 LRWD1 SMTNL1 NUP85 CEP128 JTB POLB TRAF3IP1 AAMP CCT7 CDC7 KLC2 SASS6 KLC4 TADA3 CENPV CKAP5 AGBL2 CDC20 WDR34 TUBG2 AAAS FTCD TTLL3 EFHC1 BCL2L1 UBXN6 CDK5RAP2 ODF2L DYNC1LI2 KIF21B EML6 TBCA CDC42BPG CKAP2 DNAI2 CAPRIN2 WDR35 HAUS6 DYNC2H1 NEK4 FAM161A TBC1D30 RAB3D TMUB1 KATNB1 NEURL4 SKAP1 ESRRA TTLL6 HAUS4 MARCKS TCHP CEP152 STRBP NUP62 CEP85 MICAL3 B9D1 ALMS1 APC2 TTC12 SHCBP1 NAV1 TUBGCP4 SYBU ICK CEP164 CCDC181 CLUAP1 NUBP2 DNAH1 HOOK2 TUBA4B CCDC88B RAD51 TPGS2 TRIP4 FBXW11 CHMP1A MARK4 NME7 CHD3 CDK5 AGBL5 CTTN TBCB BCAS3 CAMSAP3 CENPE DTNBP1 MAP1LC3A E4F1 SRPRB NEIL1 GOLGA2 APEX1 TTC30B CDC25B DCDC1 TUBA1C ZMYND10 MAP9 DNM1L RABL6 TTLL5 CLASP1 GSDMC BRSK2 TMEM201 KIF24 MAP2K2 NLRC5 ROR2 KIAA0586 MLLT11 DNAL4 UNC119 CEP290 SHROOM1 USP20 DNAAF1 DYNC1H1 MAK TEKT1 WRAP73 KLHL42 WDR63 BAG2 RPP25 PLK4 GSK3A FAM92B RUSC1 FAM110C PRPF19 AKAP9 PCNT DSN1	up	***
GO_BLOOD_MICROPARTICLE	0.0016891	0.0315820	0.4550599	0.4037695	1.652252	89	TF HP FGA IGKV1-17 HBA1 CP HBA2 IGKV3-15 CIB2 SLC2A1 IGKV4-1 HBB IGKV2D-28 APOL1 AGT FGG SERPINA3 OAZ3 HPR IGKV1-5 IGKV1D-33 PON1	up	*
GO_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	0.0011504	0.0241867	0.4550599	-0.3496414	-1.651846	86	HMOX1 SCIMP CD55 IL1B GAS6 SLC11A1 CD36 GATA3 IL18R1 TRAF6 IL10 TLR4 FCER1G SMAD7 TGFB2 IL6 CD160 MALT1 TBX21 CD74 TGFB1 CD81 MR1 IL18 IL18RAP NLRP3 KIT WNT5A BCL10 DDX21 SIRT1 NR4A3 CD226 CHGA TNFRSF1B TRIM6 ARG1 B2M	down	*
GO_MYELOID_LEUKOCYTE_MIGRATION	0.0001901	0.0063801	0.5188481	-0.3178518	-1.651420	157	CXCL3 IL1A SWAP70 EDNRB PECAM1 IL1B CCL3L1 C5AR1 CD9 IL1RN IL23A ANXA1 PLA2G7 JAM3 SIRPA PDE4D CCL22 PTPRO BST1 THBS1 CCL3 CXCL2 CCL4 MIR24-2 SFTPD XCL2 FCER1G DUSP1 AKIRIN1 TGFB2 NCKAP1L FLT1 IL6 HRH1 RAC2 RHOG PTGER4 CCR7 DAPK2 CXCL5 CD74 VAV3 ITGA9 FPR2 CD81 LGALS3 CCR1 PDE4B CCL20 WDR1 KIT EDN1 MTUS1 MCOLN2 ANO6 GREM1 SERPINE1 C5AR2 CX3CR1 C5 TREM2 S100A8	down	**
GO_NEGATIVE_REGULATION_OF_SECRETION	0.0001700	0.0058411	0.5188481	-0.3190497	-1.649638	159	FFAR4 RAB11FIP1 FOXF1 HMOX1 ADTRP IL1B P2RY1 STXBP6 HMGCR GAS6 CD22 ANXA1 MIR146A CARD16 ADA RAP1A RAB33B ANXA5 PPP3CA RGCC SFRP1 SRGN IL10 TACR2 REST KLF7 DPH3 MIR24-2 FRMD4A PTGER3 INHBA GNAI2 VAMP3 NOTCH1 CARD8 PTGER4 OSM CD34 CD74 STXBP3 SERPINB1 LRRC32 CRY1 SYT11 VPS4B NLRP3 EDN1 NRG1 PSMD9 ENY2 BANK1 PIM3 KALRN ACVR1C C5AR2 FKBP1B	down	**
GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	0.0012994	0.0263888	0.4550599	-0.3676769	-1.648599	69	HMOX1 SCIMP IL1B CD36 GATA3 IL18R1 TRAF6 IL10 TLR4 FCER1G SMAD7 TGFB2 IL6 CD160 MALT1 TBX21 CD74 TGFB1 CD81 IL18 NLRP3	down	*
GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION	0.0006308	0.0159311	0.4772708	-0.3184738	-1.648327	146	TNR SWAP70 CCM2L ADTRP SPN RDX BMP2 MYADM PRKAR1A CD9 IL1RN ANXA1 MIR146A SH2B3 HLX PAG1 RGCC IL10 NRARP DUSP3 KLF4 SOCS5 SFTPD SMAD7 UBASH3B GNRH1 CD80 PDE5A PODXL RC3H1 TBX21 TIGIT PPM1F PELI1 MBP RUNX3 CD74 TGFB1 YTHDF2 LRRC32 MIA3 CD86 LGALS3	down	*
GO_REGULATION_OF_ORGAN_GROWTH	0.0020007	0.0351383	0.4317077	-0.3554869	-1.647827	78	SLC6A4 RBP4 TGFBR3 TGFBR2 TBX2 WWC2 CACNA2D2 LATS2 HLX FOXC2 YBX3 TBX5 MIR17HG RBPJ NOTCH1 SAV1 PIM1 MEIS1 GATA6 RGS2 FGF2 ACACB STK4 EDN1 PTEN FGFR1 MIR548C ZFPM2 DUSP6 MAPK1 NOG	down	*
GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS	0.0000005	0.0000531	0.6594444	-0.2841315	-1.647633	367	GPR17 CD300LF FOXF1 HMOX1 TAL1 KLF13 PPARG ADTRP CD55 GATA2 SPN MNDA LPXN SAMHD1 CLEC12B PRKAR1A IL1RL1 OTUD4 CD22 TRIB1 LILRB3 FGR APOD ANXA1 MIR146A FBXO7 ADA RNF125 HLX PAG1 SERPINB9 NFE2L2 GRN CRK SFRP1 IL10 NRARP DUSP3 THBS1 SOCS5 LY96 UBQLN1 CCL3 PTPRC AXL ID2 TLR4 MIR24-2 SFTPD FCER1G DUSP1 SMAD7 INHBA IL7R UBASH3B HES1 C4BPB TGFB2 GNRH1 IL17D CD80 ELF1 CD160 APPL1 SEC14L1 PSMA1 LRCH1 NOTCH1 GABPA CUL4A PDE5A TYROBP PTGER4 PIK3R1 RC3H1 FSTL3 TBX21 CST7 TIGIT PELI1 YTHDF3 RUNX3 TREX1 CD74 CR1 SMPDL3B TGFB1 MILR1 YTHDF2 NLRP6 LRRC32 MIA3 CD86 CNOT7 PDCD1 LGALS3 MEIS1 KLRC4-KLRK1 N4BP2L2 GPR18	down	***
GO_PLASMA_MEMBRANE_RAFT	0.0015740	0.0302342	0.4550599	-0.3430151	-1.647087	95	HMOX1 DLC1 ADTRP EMP2 CAV1 CORO1C CDH13 BMPR2 ADCYAP1R1 PRKAR1A MAL CBL TGFBR2 SCN5A CD8A CAV2 MS4A1 LRP4 KCNMA1 PTGIS ADD1 HCK KCNA5 ADRA1A PRKACA CLN3 EHD2	down	*
GO_MEIOTIC_CELL_CYCLE_PROCESS	0.0005189	0.0141346	0.4772708	0.3772607	1.645812	129	TRIP13 BUB1B MND1 TTK ASPM PLK1 NUF2 PTTG1 ESPL1 FIGNL1 RAD54B CDC25A TDRKH NCAPD2 STAG3 FBXO43 BUB1 FANCA MSX2 TOP2A AURKA EME1 REC8 SYCP2 MSX1 NSUN2 RAD54L FANCD2 HORMAD1 CDC25C EME2 BRIP1 SUN1 CCNE1 TUBG1 RAD51D FZR1 SLX4 RAD50 ANKRD31 KLHDC3 MEI1 CDC20 TUBG2 FANCM	up	*
GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT	0.0000000	0.0000000	0.8986712	-0.2685362	-1.644564	844	ANGPT4 SEMA6B SEMA3G SEMA6A EREG MGAT3 ACVRL1 SASH1 FOXF1 HMOX1 SWAP70 TEK CXCL16 GCSAML ACE PHACTR1 DLC1 SGK3 PECAM1 PPARG ADTRP ROBO4 GLIPR2 GATA2 SPN IL1B TIE1 WNT4 EMP2 RDX RAPGEF2 BMPER BMP2 CDH5 ENG BAG4 LDB2 CAV1 CORO1C MYADM CITED2 CDH13 BMPR2 TBXA2R C5AR1 S1PR1 FGF10 MIR27B TGFBR3 NEDD9 CD9 GAS6 LAMP1 TGFBR2 TRIB1 SCN5A IL23A FGR RHOA NUMB APOD SEMA6D ANXA1 MIR146A MMRN2 PLA2G7 PTPRM MCTP1 SEMA3B HBEGF ADA ARSB ADAM17 LMNA PLXNA2 CLEC7A ITGA5 HSPB1 ANXA5 FOXP1 ADIPOR1 ABHD6 DACH1 GATA3 PPP3CA JAM3 PLXNA4 RGCC NFE2L2 GRN CRK SFRP1 AKT3 SPRY2 WNT3A ARHGEF2 PDE4D PDGFA FOXC2 NODAL RHOB ADARB1 MAP2K3 ROCK2 STAT5A AMOTL1 SNAI1 DUSP3 TNNC1 SDCBP PTPRO BST1 ZSWIM6 TRIM46 TACR2 PTAFR KLF4 ROCK1 DAB2 THBS1 ADAMTS9 CLDN5 CLIC4 SPAG9 CCL3 SSH1 ITGAX PTPRC SELP CCL4 JAM2 MIR24-2 RECK XCL2 DUSP1 PIK3C2A SMAD7 TBX5 OXSR1 NUS1 GNAI2 RUFY3 IL24 ANXA3 AKIRIN1 MAPRE2 ARHGDIB TGFB2 STK24 GNRH1 SRF SRGAP2C NCKAP1L PRCP KANK1 MYO1C FAM107A SLC8A1 FLT1 IL6 SGK1 APPL1 PODN MAGI2 JUN MITF LRCH1 NOTCH1 RHOBTB2 ETS1 RAC2 MAP4K4 ELP5 DUOX1 RHOG RHOJ PTGER4 PODXL CCR7 DAPK2 PIK3R1 ACKR3 PRKCE GPR183 DOCK8 PPM1F MCAM PLCG2 CD151 RRAS PTP4A1 FOXO3 EPPK1 CD74 WNT11 TTBK2 TGFB1 OSGIN1 FPR2 MIR23A CYGB MIA3 IRS2 CD81 SOD2 LGALS3 KLRC4-KLRK1 MYOCD CCR1 CLASP2 GNA13 MACF1 GPR18 PLAA SPOCK2 ADAM10 PDE4B CCL20 HACE1 CCR6 ICAM1 LDLRAD4 FGF2 ABL2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 TIAM1 CXCR4 ARHGAP18 SP100 EPHA2 RND1 GLUL LIMCH1 RET ABI3 KIT EDN1 DOCK10 SCAI KLRK1 PTEN MTUS1 PRKG1 FGFR1 NRP2 DOCK4 NRG1 RHOT1 IQGAP1	down	***
GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS	0.0031087	0.0477205	0.4317077	-0.3714894	-1.643932	64	HMOX1 TEK GATA2 SFRP4 RAMP2 ECSCR GAS6 GATA3 RGCC NFE2L2 TCF7L2 THBS1 MIR24-2 WFS1 IL6 CD160 NDNF SRSF6 SPOP SORT1 ICAM1 ARRB2 BOK ANO6 SERPINE1	down	*
GO_INTERLEUKIN_1_PRODUCTION	0.0023908	0.0397462	0.4317077	-0.3487184	-1.643573	84	NLRC4 ACP5 IL1B MNDA LPL GAS6 CD36 ANXA1 CARD16 CD33 CLEC7A HSPB1 FOXP1 SIRPA IL10 MEFV CASP1 CCL3 TLR4 CARD8 TYROBP CCR7 MALT1 SUCNR1 SERPINB1 ORM2 MR1 ARRB2 RIPK2 NLRP3 HAVCR2	down	*
GO_SPECIFIC_GRANULE	0.0006016	0.0154349	0.4772708	-0.3208399	-1.642732	131	SLPI OLR1 HVCN1 RAB44 CLEC12A PTPRB OSCAR CHIT1 CD36 SLC44A2 CD33 RAP1A PTX3 STOM LAIR1 CD93 LAMTOR3 BST1 PLAUR STX3 ATP6V1D CTSD TMBIM1 ERP44 NFKB1 HPSE CD53 DEGS1 ANXA3 CMTM6 HGSNAT SNAP23 CTSZ ATP11A ALDH3B1 TIMP2 STXBP3 FPR2 TSPAN14 GPR84 ORM2 ADAM10	down	*
GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	0.0028805	0.0455402	0.4317077	0.4067371	1.642340	82	HMGA2 DDX11 FOXM1 EYA1 EYA2 TIMELESS BRCA1 NPAS2 EEF1E1 ATR MSX1 PRKDC EGFR XRCC1 PLA2R1 PARP1 MAD2L2 RAD9A MGMT NUDT16 PARP9 UBE2V2 ANKRD1 UIMC1 DTX3L EYA4 PAXIP1 PIAS4 TMEM161A SPIDR HDAC10 SPRED3	up	*
GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE	0.0005734	0.0150935	0.4772708	-0.3336415	-1.641981	114	FFAR4 GPR17 ACP5 FOXF1 TEK PPARG WFDC1 CDH5 CALCRL APOD MIR146A ADA GATA3 SIRPA RB1 GRN IL10 MEFV KLF4 SOCS5 NFKB1 NR1D2 PTPRC PTGIS SOCS3 PSMA1 ETS1 PTGER4 CST7 SMPDL3B FPR2 NLRP6	down	*
GO_REGULATION_OF_CELL_ACTIVATION	0.0000000	0.0000071	0.7195128	-0.2785105	-1.640553	480	SIRPB1 CD300LF FOXF1 HMOX1 CD55 GATA2 SPN IL1B MNDA PLA2G10 THBD FYN CAV1 PRAM1 FGF10 PRKAR1A CDC42 IL1RL1 CD9 GAS6 LAMP1 CD22 TGFBR2 IL23A FGR RHOA ANXA1 SH2B3 CLCF1 FBXO7 CD5 ADA CLEC7A MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 GRN SFRP1 WNT3A ZEB1 MAPK8IP1 TFRC PDGFA SLC7A2 ZMIZ1 IL10 NRARP DUSP3 BST1 SLC46A2 PTAFR THBS1 CEBPA CLECL1 SOCS5 MPL FAM49B CCL3 CDKN1A PTPRC SELP AXL ID2 TLR4 IGFBP2 SFTPD FCER1G SMAD7 PLEK INHBA IL7R UBASH3B CYP26B1 HES1 MIR17HG GNRH1 NCKAP1L CD80 IL6 CD160 PDE5A RAC2 TYROBP CCR7 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 RPS6KA1 DOCK8 AP3B1 TBX21 ZNF683 CST7 TIGIT PELI1 TNFSF13 RUNX3 TREX1 CD74 CR1 TGFB1 VAV3 AP1G1 CD1D ZBTB1 MILR1 CD6 TEC CYGB LRRC32 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23	down	***
GO_COAGULATION	0.0000120	0.0007286	0.5933255	-0.2940697	-1.638642	260	CLEC1B ADTRP GATA2 F2RL3 P2RY1 THBD RCOR1 TRPC3 FYN MMRN1 CAV1 TBXA2R PRKAR1A CDC42 CD9 GAS6 HPS5 PEAR1 CD36 SH2B3 FOXA2 ENTPD1 CSRP1 HSPB1 ANXA5 SLC7A11 GATA3 NFE2L2 WNT3A PDGFA ARRB1 DGKE PLAUR THBS1 MAFG MPL ITPK1 DOCK9 SELP AXL HPSE TLR4 CAPZA2 FCER1G PLEK GNAQ UBASH3B PIK3R5 C4BPB MAFF VWF PROCR SRF PRCP METAP1 IL6 PSEN1 ENPP4 PIK3R1 PABPC4 PRKCE PRKACA DOCK8 AP3B1 YWHAZ CD34 PLCG2 EHD2 PRKCG MYL12A DGKG STXBP3 EHD1 VAV3 TEC GATA6 GNA13 DOCK6 TFPI ARRB2 RAB5A ACTB ADORA2A JMJD1C MAFK EDN1 SCUBE1 PRKG1 P2RX1 ZFPM2 EHD3 ANO6 PAPSS2 IRF2 SERPINE1 TREML1 CAPZB MAPK1 PRKCH	down	***
GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	0.0013194	0.0265813	0.4550599	-0.3439661	-1.638079	92	FOXF1 HMOX1 CD55 CLEC12B CD22 ANXA1 RNF125 HLX SERPINB9 GRN CRK IL10 SOCS5 PTPRC SMAD7 IL7R C4BPB TGFB2 APPL1 SEC14L1 RC3H1 TBX21 CR1 TGFB1 LGALS3	down	*
GO_REGULATION_OF_RNA_SPLICING	0.0006727	0.0167904	0.4772708	-0.3369878	-1.636910	110	PRX SRSF7 DYRK1A RBM7 TRA2B RBM4 SRSF2 CLK1 HNRNPU CWC22 AHNAK SRSF5 REST CLK4 SRSF3 CELF1 DDX17 WTAP PIK3R1 SMU1 DDX5 MBNL2 RBM22 CELF2 SRSF6 HNRNPA2B1 JMJD6 SRSF4 KHDRBS1 MAGOH MBNL1 HNRNPK NUP98 SRSF10 RPS13 THRAP3 HNRNPH1 ZNF326 YTHDC1 SETX RBMXL1 SAP18 FUS SNW1	down	*
GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA	0.0000606	0.0026237	0.5573322	-0.3012544	-1.633881	209	SMAD6 ACVRL1 CLEC3B WNT4 CDH5 ENG FOLR1 FYN CAV1 CITED2 NR3C1 TGFBR3 CBL TGFBR2 RHOA PDE2A LTBP4 ADAM17 NLK CAV2 CRK SFRP1 ZEB1 NODAL ROCK2 PRDM16 SDCBP NPNT LIMS1 ROCK1 DAB2 THBS1 CLDN5 SMAD7 VEPH1 HTRA4 MIR17HG TGFB2 NRROS ADAMTSL2 APPL1 JUN LTBP2 FERMT2 SKIL CREB1 FOS UBB RUNX3 TGFB1 PARD6A ZFYVE9 TGFB1I1 LRRC32 MYOCD LTBP1 SMAD2 LDLRAD4 EPB41L5 ARRB2 CDKN1C CREBBP ING2 EDN1 SKI LTBP3	down	**
GO_MICROTUBULE_ORGANIZING_CENTER	0.0000001	0.0000079	0.7195128	0.3249837	1.633117	643	CCNO PKHD1 DDX11 CEP72 SPICE1 MDM1 RUVBL1 CEP89 CDC45 RPGRIP1L BUB1B NEK2 ZNF12 CCNB1 CENPF STOX1 NDC80 MKS1 CCDC113 BRCA1 FANK1 BRSK1 IFT122 CCDC14 CNTD2 ASPM STIL TTC26 CEP70 PLK1 IFT27 AURKB ESPL1 CCNB2 PLEKHA7 XRCC2 CCNF DTL CIB1 HNF4G ZFYVE19 CDK5RAP3 DCTN2 SPDL1 WDR90 SPPL2B NME1 MICALL2 HAUS5 RANBP1 CEP250 WDR62 RUVBL2 HMMR KIF23 CEP55 BBS1 BOD1 CUL7 BICD1 KIF15 TSGA10 KIF3B CCDC13 CCDC77 AUNIP TOP2A FBF1 MAP10 CCT5 AURKA ODF2 SFI1 IFT43 SNCG KIF2C MAD1L1 POC1A AGBL4 MPHOSPH9 TTLL12 TEKT2 FSD1 HOOK1 DCDC2 GPSM2 MCM3 WDR60 TOPBP1 CHEK1 NEK11 IFT172 CC2D1A CKAP2L GAS8 CBY1 TMEM63A RAD18 RABEP2 LRRC45 C2CD3 C4orf47 DLG5 CCDC78 KNSTRN KRT18 IQCB1 CDK1 CROCC CCDC61 CEP97 CENPJ KIAA0753 POC5 E2F1 PSMB5 ALDOB KIF2A ANKRD26 KIF7 SSX2IP CCDC88C DYNLL2 SPAG5 TTC23L POC1B RAB11FIP4 TRAF5 LCA5 KCTD1 KLHL22 FGFR1OP IFT52 MZT2A MZT2B CEP63 BBS5 CCNE1 CEP192 EXOC7 TUBG1 DLGAP5 NINL TACC3 CCDC151 RAD51D CCDC146 KIF20B LRWD1 SMTNL1 CEP128 JTB TRAF3IP1 SASS6 CKAP5 AGBL2 CDC20 WDR34 TUBG2 AAAS FTCD EFHC1 BCL2L1 UBXN6 CDK5RAP2 ODF2L DYNC1LI2 CDC42BPG CKAP2 CAPRIN2 WDR35 HAUS6 NEK4 FAM161A TBC1D30 TMUB1 KATNB1 NEURL4 TTLL6 HAUS4 MARCKS TCHP CEP152 NUP62 CEP85 MICAL3 B9D1 ALMS1 TTC12 TUBGCP4 ICK CEP164 CLUAP1 NUBP2 HOOK2 CCDC88B RAD51 TRIP4 FBXW11 CHMP1A MARK4	up	***
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION	0.0000469	0.0021484	0.5573322	-0.3094170	-1.632433	185	SIRPB1 CD55 IL1B FYN CD44 CAV1 CDC42 TGFBR2 IL23A RHOA ANXA1 CD5 ADA MAP3K8 HLX GATA3 SIRPA TRAF6 TFRC ZMIZ1 PTAFR CLECL1 SOCS5 FAM49B PTPRC IGFBP2 IL7R HES1 NCKAP1L CD80 IL6 CD160 ETS1 CCR7 PIK3R1 CD83 GRB2 MALT1 DOCK8 AP3B1 RUNX3 CD74 CD1D ZBTB1 CD6 CD86 PDCD1 CD81 KLRC4-KLRK1 ICAM1 IL18 RIPK2 NLRP3 HAVCR2 PAK2 KLRK1 TNFSF9	down	**
GO_CENTROSOME	0.0000006	0.0000625	0.6594444	0.3304218	1.631901	501	CCNO PKHD1 DDX11 CEP72 SPICE1 MDM1 CEP89 CDC45 RPGRIP1L NEK2 ZNF12 CCNB1 CENPF STOX1 NDC80 MKS1 CCDC113 BRSK1 CCDC14 CNTD2 ASPM STIL TTC26 CEP70 PLK1 IFT27 AURKB ESPL1 CCNB2 PLEKHA7 XRCC2 CCNF DTL CIB1 HNF4G ZFYVE19 CDK5RAP3 DCTN2 SPPL2B NME1 HAUS5 RANBP1 CEP250 WDR62 RUVBL2 HMMR KIF23 CEP55 BBS1 BOD1 CUL7 BICD1 KIF15 KIF3B CCDC13 CCDC77 AUNIP FBF1 MAP10 CCT5 AURKA ODF2 SFI1 IFT43 SNCG KIF2C MAD1L1 POC1A FSD1 HOOK1 DCDC2 GPSM2 MCM3 WDR60 CHEK1 NEK11 CKAP2L TMEM63A RAD18 RABEP2 LRRC45 C2CD3 C4orf47 KNSTRN KRT18 IQCB1 CDK1 CROCC CCDC61 CEP97 CENPJ KIAA0753 POC5 E2F1 PSMB5 ALDOB KIF2A ANKRD26 SSX2IP CCDC88C DYNLL2 SPAG5 POC1B RAB11FIP4 TRAF5 KCTD1 KLHL22 FGFR1OP IFT52 MZT2A MZT2B CEP63 BBS5 CCNE1 CEP192 EXOC7 TUBG1 DLGAP5 NINL TACC3 RAD51D KIF20B JTB TRAF3IP1 SASS6 CKAP5 CDC20 TUBG2 AAAS EFHC1 BCL2L1 CDK5RAP2 ODF2L DYNC1LI2 CDC42BPG CKAP2 CAPRIN2 WDR35 HAUS6 FAM161A KATNB1 HAUS4 MARCKS TCHP CEP152 NUP62 CEP85 B9D1 ALMS1 TTC12 TUBGCP4 CEP164 CLUAP1 NUBP2 HOOK2 CCDC88B TRIP4 FBXW11 MARK4 NME7 CHD3	up	***
GO_SPINDLE_ASSEMBLY	0.0026690	0.0431383	0.4317077	0.3957219	1.631117	93	SPICE1 CHEK2 NEK2 RACGAP1 ASPM MSTO1 PLK1 AURKB TPX2 MYBL2 HAUS5 KIF23 KIF3B MAP10 AURKA TPR CENPW KIF11 GPSM2 CEP97 BIRC5 KIF2A SPAG5 KPNB1 CEP63 CEP192 CDC20 AAAS CHMP4C HAUS6 RCC1 HAUS4 TUBGCP4 CHMP1A CHMP2A GOLGA2 MAP9 CLASP1 DRG1 DYNC1H1 WRAP73 FBXO5 TUBGCP2 LZTS2	up	*
GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	0.0001436	0.0051107	0.5188481	-0.3127197	-1.630474	172	RBP4 FOXF1 HMOX1 SCIMP GATA2 PGC IL1B CD1C LAMP1 IL23A FGR CD36 ANXA1 CLCF1 RAP1A HLX GATA3 IL18R1 TRAF6 CRTAM TFRC PTAFR SOCS5 FAM49B CADM1 PTPRC TLR4 FCER1G CD80 IL6 CD160 RAC2 RAPGEF1 STX7 MALT1 TBX21 TNFSF13 CD74 TGFB1 AP1G1 CD1D ZBTB1 CD86 CD81 KLRC4-KLRK1 FCGRT UNC13D IL18 IL18RAP RIPK2 NLRP3 CD1E KLRK1	down	**
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION	0.0026914	0.0433964	0.4317077	-0.3635578	-1.630381	67	SPN IL23A ANXA1 FOXP1 HLX GATA3 IL18R1 FUT7 SOCS5 SMAD7 NCKAP1L CD80 IL6 PTGER4 CD83 GPR183 MALT1 RC3H1 TBX21 RUNX3 CD86 IL18 SEMA4A RIPK2 NLRP3	down	*
GO_CYTOPLASMIC_REGION	0.0001204	0.0044538	0.5384341	0.3558755	1.630008	202	KIF1A GRIK2 DNAH2 RPGRIP1L AP3B2 CENPF UCHL1 SPAG17 ANLN PCLO DNAH3 AK8 DNAI1 ARMC4 BBS1 SPAG16 KIF3B HYDIN WDR78 CCDC114 DCDC2 GPSM2 BLOC1S1 WDR66 DNAH8 IFT172 GAS8 DNAH11 TULP3 CCDC40 DRC1 KIF5A AP3D1 ERC2 KIF19 SPAG6 SAPCD2 LCA5 MYO5B DNAH5 RANGAP1 SPEF1 BBS5 SPG7 DNAH7 MNS1 CCDC151 HIP1R CLTA TRAF3IP1 CLTB DNAJB13 WDR34 TTLL3 EFHC1 AP3M2 RPGRIP1 BSN DNAI2 WDR35 DYNC2H1 NEK4 RSPH4A TCHP SYBU DNAH1 PPFIA3 TRAK1 WLS MAPK8IP3 DTNBP1 TTC30B RIMS1 ENO1 CLASP1 DNAAF1 DYNC1H1 MAK GLI3 WDR63	up	**
GO_LEUKOCYTE_MEDIATED_IMMUNITY	0.0000000	0.0000001	0.8140358	-0.2659400	-1.627856	675	SIRPB1 SLPI FOXF1 HMOX1 SWAP70 FCN1 OLR1 ACE SCIMP PECAM1 HVCN1 CD55 GAPT GATA2 IL1B MNDA LTA4H CAT RAB44 EMP2 CLEC12A PTPRB OSCAR CD44 CLEC12B PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA CD1C VAPA FUCA1 LAMP1 CBL SLC11A1 LILRB3 RFTN1 IL23A CD8A FGR RHOA DNASE1L3 CD36 SLC44A2 CLCF1 DNAJC3 MAN2B1 IGKV2-28 CD33 ARSB ADAM17 ASAH1 RAP1A GM2A ANPEP PTX3 SERPINB9 STOM LAIR1 GATA3 SIRPA IL18R1 TRAF6 CD93 GRN LAMTOR3 CRK CRTAM TFRC RAB14 CD58 CST3 IL10 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D FAM49B CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 CADM1 ITGAX PTPRC SELL HPSE TLR4 ARHGAP9 CD53 PRF1 FCER1G SMAD7 GCA KLRD1 IL7R C4BPB DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP IGLV2-11 IL6 CD160 CTSS PSEN1 SNAP23 C1QA VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG STX7 ENPP4 GLIPR1 GMFG MALT1 SERPINB6 CAP1 TBX21 IGKV3-20 TNFSF13 PSMD12 ALDH3B1 TREX1 CD74 KLRC2 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 TGFB1 AP1G1 DOK3 CD1D ZBTB1 MILR1 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 ORM2 BRI3 FCGRT PLEKHO2 ADAM10 IST1 IGKV1D-39 COMMD9 UNC13D CCR6 ICAM1 IL18 IL18RAP LAT WDR1 NBN ARRB2 HSP90AA1 NLRP3 HSPA8 HAVCR2 METTL7A CD19 NHLRC3 KIT SIGLEC9 CTSC CD1E ARPC5 KLRK1 LYST SNAP29 P2RX1 PSMD6 IQGAP1 CREG1	down	***
GO_REGULATION_OF_CELL_CELL_ADHESION	0.0000033	0.0002523	0.6272567	-0.2792949	-1.621086	341	TNR SIRPB1 SWAP70 CCM2L ADTRP CD55 SPN IL1B WNT4 RDX BMP2 FYN CD44 CAV1 MYADM CITED2 PRKAR1A CDC42 CD9 IL1RN TGFBR2 IL23A RHOA ANXA1 MIR146A SH2B3 CD5 ADA FOXA2 MAP3K8 HLX PAG1 GATA3 SIRPA RGCC TRAF6 WNT3A TFRC NODAL ZMIZ1 IL10 NRARP DUSP3 DENND6A PTAFR KLF4 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SFTPD SMAD7 IL7R UBASH3B HES1 GNRH1 NCKAP1L CD80 IL6 CD160 ETS1 PDE5A PODXL CCR7 PIK3R1 CD83 GRB2 MALT1 RC3H1 DOCK8 AP3B1 FSTL3 TBX21 TIGIT PPM1F PELI1 MBP RUNX3 CD74 TGFB1 CD1D ZBTB1 CD6 YTHDF2 LRRC32 MIA3 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1	down	***
GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	0.0000082	0.0005240	0.5933255	0.3326370	1.621015	388	HMGA2 TRIP13 CEP72 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF PAGR1 STOX1 NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 DBF4B KIF14 ANLN CEP70 PLK1 AURKB ESPL1 CDC6 TPX2 TFDP2 CDC25A ORC1 DTL ZFYVE19 CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 CEP250 CASP2 HMMR BTRC SMARCD3 KNTC1 BUB1 AURKA ODF2 SFI1 TPR MAD1L1 CLSPN CDCA5 PRKDC CDC25C SOX4 EGFR TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 BLM PML CNOT3 ERCC2 STXBP4 CDKN2C ANAPC5 CTDSP2 CDK1 CENPJ RFWD3 E2F1 PSMB5 ANAPC7 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 FGFR1OP CEP63 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 NINL PSME2 MTA3 FZR1 ANAPC1 PSMD2 ATAD5 CDC7 CKAP5 PSMB3 CDC20 CHMP4C WNT10B CDK5RAP2 PRMT1 UIMC1 HAUS6 TFAP4	up	***
GO_IMMUNE_RECEPTOR_ACTIVITY	0.0010479	0.0229437	0.4550599	-0.3377428	-1.620879	100	GPR17 IL17RB CD44 CCRL2 C5AR1 IL1RL1 LIFR FZD4 IL18R1 EPOR MPL FCER1G IL7R HLA-DQA1 CD160 IL2RB IFNGR1 CCR7 ACKR3 CD74 CR1 CCR4 IFNAR1 KLRC4-KLRK1 CCR1 MR1 IFNLR1 CCR6 IL18RAP CXCR4 CCR9 KLRK1 KLRF1 CSF2RB C5AR2 GHR CTSH CX3CR1	down	*
GO_POSITIVE_REGULATION_OF_CELL_ADHESION	0.0000062	0.0004277	0.6105269	-0.2782692	-1.617122	343	SIRPB1 LIMS2 FOXF1 TEK CD55 IL1B WNT4 EMP2 FYN CD44 BAG4 CAV1 MYADM CITED2 CDH13 CDC42 MIR27B NEDD9 TGFBR2 IL23A RHOA CD36 ANXA1 CD5 ADA FOXA2 ITGA5 MAP3K8 HLX GATA3 PPP3CA SIRPA TRAF6 CRK SFRP1 WNT3A TFRC FOXC2 NODAL ZMIZ1 IL10 NPNT DENND6A LIMS1 PTAFR ROCK1 STX3 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SMAD7 IL7R HES1 TGFB2 NCKAP1L NINJ1 CD80 IL6 CD160 UTRN NDNF ETS1 MAP4K4 PODXL CCR7 PIK3R1 CD83 PRKCE GRB2 MALT1 HSD17B12 DOCK8 AP3B1 FSTL3 PPM1F RUNX3 CD74 VAV3 CD1D ZBTB1 CD6 CD86 PDCD1 CD81 KLRC4-KLRK1 SPOCK2 ABI3BP UNC13D ICAM1 IL18 ARPC2 EPB41L5	down	***
GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME	0.0027811	0.0442444	0.4317077	-0.3441662	-1.616202	81	SRSF7 DYRK1A RBM7 TRA2B RBM4 SRSF2 HNRNPU CWC22 SRSF5 REST SRSF3 CELF1 DDX17 WTAP SMU1 DDX5 MBNL2 CELF2 SRSF6 HNRNPA2B1 JMJD6 SRSF4 KHDRBS1 MAGOH MBNL1 HNRNPK NUP98 SRSF10 THRAP3 YTHDC1 RBMXL1 SAP18	down	*
GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION	0.0000037	0.0002723	0.6272567	-0.2788561	-1.616202	358	POLR3H EREG IL17RB IL1A HMOX1 FCN1 SCIMP SIGLEC16 CCM2L SPN IL1B MNDA LRRFIP1 LPL MYD88 C5AR1 IL1RL1 IL1RN SLC11A1 IL23A FGR HEG1 CD36 ANXA1 TNFRSF8 ADAM17 CLEC7A HSPB1 RNF125 GATA3 RGCC IL18R1 TRAF6 SPTBN1 CRTAM WNT3A ARHGEF2 PDE4D CD58 NODAL IL10 ROCK2 BIRC2 CASP1 PTAFR THBS1 LY96 FAM49B CCL3 NFKB1 CADM1 PTPRC HPSE TLR4 FCER1G CLEC9A IL17D CD80 IL6 CD160 PSEN1 APPL1 SEC14L1 CARD8 TYROBP HSPA1B IFNGR1 PTGER4 CCR7 PIK3R1 CD83 IRF8 CREB1 OSM MALT1 TIGIT CD34 PLCG2 PELI1 MBP CD74 WNT11 IRF5 CHIA TGFB1 AKIRIN2 CD6 CD86 CD81 KLRC4-KLRK1 ORM2 PDE4B IL18 RIPK2 NLRP3 HAVCR2 CREBBP KLRK1 MCOLN2 AIM2 RORA PUM1 ATF4 FLT4 SPHK1 CSF2 CYBA EGR1 SERPINE1 ATF2 CLEC4E C5 TREM2 TBC1D23 NFAM1 POLR2L WNT5A BCL10 AKAP12 HMGB1 DDX21 EP300 CD3E IRF1	down	***
GO_MEIOTIC_CELL_CYCLE	0.0005837	0.0151676	0.4772708	0.3584788	1.614921	169	TRIP13 BUB1B NEK2 MND1 TTK SLC26A8 ASPM PLK1 NUF2 PTTG1 ESPL1 FIGNL1 RBBP8 RAD54B CDC25A XRCC2 TDRKH NCAPD2 RSPH1 EXO1 STAG3 FBXO43 BUB1 FANCA MSX2 TOP2A AURKA EME1 REC8 SYCP2 MSX1 NSUN2 RAD54L FANCD2 HORMAD1 CDC25C EME2 BRIP1 SUN1 METTL3 CCNE1 TUBG1 MNS1 RAD51D FZR1 SLX4 RAD50 ANKRD31 KLHDC3 MEI1 CDC20 TUBG2 RPA1 FANCM	up	*
GO_PLASMA_MEMBRANE_BOUNDED_CELL_PROJECTION_CYTOPLASM	0.0007289	0.0178856	0.4772708	0.3595574	1.614242	165	KIF1A GRIK2 DNAH2 RPGRIP1L AP3B2 CENPF UCHL1 SPAG17 DNAH3 AK8 DNAI1 ARMC4 BBS1 SPAG16 KIF3B HYDIN WDR78 CCDC114 DCDC2 BLOC1S1 WDR66 DNAH8 IFT172 GAS8 DNAH11 TULP3 CCDC40 DRC1 KIF5A AP3D1 KIF19 SPAG6 LCA5 DNAH5 RANGAP1 SPEF1 BBS5 SPG7 DNAH7 MNS1 CCDC151 HIP1R TRAF3IP1 DNAJB13 WDR34 TTLL3 EFHC1 AP3M2 RPGRIP1 DNAI2 WDR35 DYNC2H1 NEK4 RSPH4A SYBU DNAH1 TRAK1 WLS MAPK8IP3 DTNBP1	up	*
GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	0.0020723	0.0358264	0.4317077	-0.3278313	-1.612561	112	IL1B CLEC12B CD1C LAMP1 IL23A CLCF1 SERPINB9 GATA3 IL18R1 TRAF6 CRK CRTAM TFRC IL10 FAM49B CADM1 PTPRC FCER1G SMAD7 IL7R C4BPB IL6 CD160 STX7 MALT1 TBX21 TNFSF13 CR1 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT IL18 IL18RAP ARRB2 NLRP3 HAVCR2 CD1E KLRK1	down	*
GO_NUCLEOTIDE_PHOSPHORYLATION	0.0023177	0.0388873	0.4317077	0.3801711	1.609149	109	HKDC1 AK4 NUP107 PGM2L1 DDIT4 GPI GAPDH ALDOC AK8 NME1 NUP155 TPR NME9 PKM NME5 PFKP ALDOA ENTPD5 GCKR ALDOB BPGM NUP205 AK7 PRKAA2 EIF6 FOXK1 DTYMK NUP85 DHTKD1 AAAS PFKFB4 ESRRB NUP62 NME4 HK2 SEC13 PFKM NME7 PGAM1 SIRT6 PNKP ENO1 NUP210 NUP93 PRKAG1	up	*
GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS	0.0001465	0.0051716	0.5188481	0.3409866	1.607809	264	CPS1 GPT GPT2 BHMT ACMSD PSPH NOXRED1 SLC25A21 PHGDH GMPS ALDH18A1 GLDC PAH ACY1 SHMT2 DPYS AARS2 GFPT1 EEF1E1 IDO1 BPHL LARS2 GCAT MCCC2 AIMP2 PYCR2 TARS2 OAZ3 SARS2 ASS1 AHCY PSMD4 CAD TST HARS2 PLOD2 GOT2 OAT PSMB5 PSAT1 PSMC4 HYKK PARS2 SCLY FAH PSMA5 GSS ALDH7A1 AARSD1 PSME2 ENOSF1 ASNS PSMD2 SLC1A3 MAT1A YARS2 NAGS PFAS PSMB3 IARS2 HPD FTCD SIRT4 NAT8L PHYKPL ASRGL1 HIBADH PRODH AMT GGT5 PSMB4 GAD1 FARSA DDAH1 PYCR1 AGMAT FARSB NOS1 EARS2 MTHFD1 SEPHS1 PCBD1 BCAT2 FOLH1 ACAD8 NQO1 SARDH BCKDK NOS3 HGD DPYD PSMB10 PSME1 ASL MPST PLOD1 GCSH MTR SHMT1 MTRR MARS2 NIT2 PPA1 PLOD3 TXN2 AFMID MCCC1 PSMD3 HAL CARNS1 HAAO TPH1	up	**
GO_REGULATION_OF_CELL_CYCLE_PROCESS	0.0000002	0.0000251	0.6901325	0.3198433	1.606511	633	HMGA2 PKHD1 TRIP13 DDX11 FOXM1 CEP72 SPICE1 KIF20A MDM1 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF PAGR1 STOX1 NDC80 BRCA1 TTK CDK4 SMPD3 RACGAP1 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN STIL CEP70 PLK1 AURKB PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 TFDP2 RBBP8 CDC25A PRC1 ORC1 CCNF DTL ZFYVE19 CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 CASP2 HMMR BTRC SMARCD3 KIF23 MKI67 CUL9 CUL7 FBXO43 KNTC1 RHNO1 KIF3B BUB1 MSX2 MAP10 GPER1 AURKA CBX3 ODF2 SFI1 TPR MAD1L1 MSX1 POC1A CLSPN CXCR5 RRM2 CDCA5 PRKDC FSD1 TOM1L1 KIF11 GPSM2 HORMAD1 CDC25C SOX4 EGFR TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 AKT2 MGA PKMYT1 BLM PML CNOT3 ERCC2 STXBP4 PSRC1 INCENP KNSTRN CDKN2C NUSAP1 CBX5 ANAPC5 CTDSP2 CDK1 CEP97 CENPJ RFWD3 E2F1 PSMB5 ANAPC7 FEN1 EZH2 CNOT11 SPAG5 EGF RAB11FIP4 MTBP PSMC4 MAD2L2 KLHL22 FGFR1OP GIPC1 MYO19 ANKK1 CEP63 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 NINL TACC3 PSME2 MTA3 TRIM37 MYBBP1A FZR1 PKP4 NUDT16 KIF20B ANAPC1 SND1 CDK13 PSMD2 ATAD5 CDC7 ANKRD31 SH2B1 CENPV CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B BCL2L1 CHMP4C WNT10B CDK5RAP2	up	***
GO_REGULATION_OF_TUBE_SIZE	0.0017639	0.0326794	0.4550599	-0.3297511	-1.606506	109	SLC6A4 HMOX1 ACE EDNRB P2RY1 CAV1 ADRA1D BMPR2 TBXA2R HMGCR RHOA ATP2B1 PTPRM ADRB1 ADRB2 FOXC2 ROCK2 KCNMA1 PTAFR ROCK1 PER2 P2RY2 KCNMB1 PIK3C2A RAP1GDS1 KCNA5 SLC8A1 HRH1 ADRA1A	down	*
GO_CELL_CYCLE_PHASE_TRANSITION	0.0000007	0.0000643	0.6594444	0.3240005	1.606450	530	HMGA2 CCNO TRIP13 FOXM1 CEP72 CDC45 TICRR MCM10 CHEK2 BUB1B NEK2 CCNB1 CENPF TIMELESS PAGR1 STOX1 NDC80 PRIM2 BRCA1 TTK CDK4 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 ANLN POLE CNTD2 CEP70 PLK1 AURKB ESPL1 CDC6 TPX2 TFDP2 CCNB2 RBBP8 MCM4 MCM2 TYMS CDC25A ORC1 CCNF DTL MCM8 ZFYVE19 CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 CEP250 CASP2 MELK HMMR BTRC SMARCD3 KNTC1 BUB1 AURKA ODF2 POLA2 SFI1 TPR MCM7 MAD1L1 CLSPN RRM2 CDCA5 PRKDC MCM3 CDC25C SOX4 EGFR TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 MDM2 PKMYT1 FBXL8 BLM PML CNOT3 ERCC2 MNAT1 STXBP4 SKP2 CKS1B CDKN2C ANAPC5 CTDSP2 CDK1 POLE2 CENPJ RFWD3 GMNN E2F1 PSMB5 CCNJL ANAPC7 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP CEP63 CCNE1 CEP192 CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 NINL TACC3 PSME2 MTA3 AKAP8L FZR1 ANAPC1 PSMD2 ATAD5 PPME1 CDC7 CKAP5 PSMB3 CDC20 RPA1 CHMP4C WNT10B CDK5RAP2 MCM6 PRMT1 MCM5 UIMC1 HAUS6 TFAP4 RCC1 CCNG1 HAUS4 PSMB4	up	***
GO_GRANULOCYTE_MIGRATION	0.0013049	0.0264468	0.4550599	-0.3354038	-1.604810	97	CXCL3 IL1A PECAM1 IL1B CCL3L1 C5AR1 IL1RN IL23A ANXA1 JAM3 PDE4D CCL22 BST1 THBS1 CCL3 CXCL2 CCL4 XCL2 FCER1G AKIRIN1 TGFB2 NCKAP1L HRH1 RAC2 RHOG PTGER4 CCR7 DAPK2 CXCL5 CD74 VAV3 ITGA9 LGALS3 PDE4B CCL20 WDR1	down	*
GO_CAVEOLA	0.0023925	0.0397462	0.4317077	-0.3572469	-1.601832	69	HMOX1 DLC1 ADTRP EMP2 CAV1 CORO1C CDH13 BMPR2 ADCYAP1R1 CBL TGFBR2 SCN5A CAV2 KCNMA1 PTGIS HCK KCNA5 ADRA1A CLN3 EHD2	down	*
GO_NEUTROPHIL_MIGRATION	0.0023404	0.0391375	0.4317077	-0.3446419	-1.601207	79	CXCL3 IL1A PECAM1 IL1B CCL3L1 C5AR1 IL1RN IL23A JAM3 PDE4D CCL22 BST1 CCL3 CXCL2 CCL4 XCL2 FCER1G TGFB2 NCKAP1L RAC2 RHOG CCR7 DAPK2 CXCL5 CD74 VAV3 ITGA9 LGALS3 PDE4B CCL20 WDR1	down	*
GO_G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY	0.0000852	0.0033722	0.5384341	-0.2882414	-1.601200	240	FFAR4 HCRTR1 GPR17 RAMP3 GPR15 EDNRB PPARG F2RL3 LHCGR P2RY1 GPR65 RAMP2 HCAR2 CCRL2 INPP5K CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 SSTR1 FZD4 NMUR1 ADRB1 ADRB2 GPBAR1 GPR4 TAPT1 PTGIR TACR2 PTAFR NPR3 P2RY2 GPR85 PTGER3 GPR157 PTH1R S1PR4 HCAR3 GPR61 TAS1R1 HRH1 ADRA1A GPR141 PTGER4 CCR7 ACKR3 GPR183 PTGER2 NPR1 SUCNR1 OGFRL1 GPRC5A TPRA1 GPR37L1 GPR3 CCR4 FPR2 NLRP6 GPR84 MRGPRF CCR1 OR52B6 GPR18	down	**
GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM	0.0006320	0.0159311	0.4772708	-0.3115394	-1.599313	139	SLC6A4 HMOX1 TEK ACE EDNRB P2RY1 RAMP2 CDH5 CAV1 ADRA1D BMPR2 TBXA2R HMGCR RHOA PDE2A ATP2B1 PTPRM ADRB1 ADRB2 FOXC2 ROCK2 KCNMA1 TACR2 PTAFR ROCK1 PER2 P2RY2 KCNMB1 PIK3C2A RAP1GDS1 KCNA5 SLC8A1 HRH1 ADRA1A	down	*
GO_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	0.0010587	0.0229576	0.4550599	-0.3199707	-1.597929	122	ACP5 SPN LPL GAS6 IL23A CD36 TNFRSF8 CD33 CLEC7A HSPB1 FOXP1 SIRPA ARHGEF2 IL10 PTAFR THBS1 LY96 CCL3 PTPRC AXL TLR4 FCER1G PSEN1 TYROBP IFNGR1 PIK3R1 CD34 AZI2 TREX1 CD86 ORM2 GPR18 TSPO SYT11 ARRB2 RIPK2 HAVCR2 CYBA C5AR2 CX3CR1 TREM2 ZFP36 TBC1D23 WNT5A BCL10 AKAP12 HMGB1	down	*
GO_CIRCULATORY_SYSTEM_DEVELOPMENT	0.0000000	0.0000000	0.8753251	-0.2574712	-1.597019	901	SMAD6 ANGPT4 RBP4 EPAS1 SEMA6A EREG HSPB7 RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK PDLIM2 DLC1 TAL1 PECAM1 RASIP1 CCM2L PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB BMP2 SIK1 CDH5 ENG LYL1 ARHGEF15 FOLR1 ECSCR SOX17 CAV1 CITED2 FOSL1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 PRKAR1A MEF2A CDC42 MIR27B TGFBR3 TGFBR2 NFATC3 SCN5A HSPG2 HEG1 RHOA PDE2A KCNAB1 APOD JPH2 ANXA1 TBX2 MIR146A MMRN2 PTPRM LMNA RAP1A TMEM204 ITGA5 CLEC14A HSPB1 LUZP1 FZD4 ANPEP GATA3 NR4A1 JAM3 RB1 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A HNRNPU SPI1 TCAP TCF7L2 PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 MMP21 ROCK2 AMOTL1 SNAI1 NRARP TNNC1 FOXO1 TBX4 EPOR TNFSF12 TSPAN12 KLF4 REST ID3 ROCK1 ZFAND5 GAA THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 CDKN1A PDE3B ITGAX EPGN HPSE ID2 MIR24-2 RECK PIK3C2A ELK3 SMAD7 ZMPSTE24 ADIPOR2 MBD2 TBX5 SH2D2A MYH11 NUS1 PTGIS DCHS1 HES1 MIR17HG PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ SLC8A1 FLT1 IL6 WASF2 PKNOX1 CD160 PSEN1 SOCS3 NDNF JUN NOTCH1 ETS1 ADRA1A JUNB EPC1 JAK1 RHOJ RAPGEF1 ACKR3 CREB1 NPR1 TBX21 NDST1 NDUFV2 MCAM CD34 POGLUT1 RRAS KLF2 CACYBP GJA4 PKD2 TREX1 WNT11 SYPL2 SAV1 TGFB1 VAV3 ISM1 JMJD6 MIR23A PDLIM1 MIA3 PIM1 COL15A1 SOD2 MEIS1 MYOCD GATA6 GNA13 ACTN2 RGS2 LTBP1 KAT2B ADAM10 PRICKLE4 RXRA SMAD2 FGF2 IL18 PDLIM5 FKBP1A VASH1 EGFL7 EPN2 ARRB2 OSR1 SETDB2 SEMA4A RTN4 CXCR4 TAB2 PTCH1 SP100 ACACB EPHA2 PARVA GLUL STK4 RAPGEF3 KIT EDN1 SCUBE1 ETV2 FOXJ2 PTEN SYNPO2L FGFR1 RORA MIR548C LDLR NRP2 NRG1 NAA15 ZFPM2	down	***
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	0.0014711	0.0288355	0.4550599	-0.3296176	-1.596343	104	SCIMP GATA2 IL1B CD1C LAMP1 IL23A FGR CLCF1 GATA3 IL18R1 TRAF6 CRTAM TFRC PTAFR FAM49B CADM1 PTPRC FCER1G IL6 CD160 STX7 MALT1 TBX21 TNFSF13 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT IL18 IL18RAP NLRP3 CD1E KLRK1	down	*
GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS	0.0000560	0.0024763	0.5573322	-0.2903522	-1.595911	225	SMAD6 SEMA6A ACVRL1 SOSTDC1 HHEX SFRP4 IL1B WNT4 GREM2 BMPER CDH5 ENG FOLR1 CAV1 CITED2 BMPR2 FGF10 TGFBR3 TGFBR2 TMPRSS6 MIR146A MMRN2 LTBP4 ADAM17 TMEM204 ITGA5 FZD4 CAV2 GATA3 SFRP1 SPRY2 ZEB1 PRDM16 SDCBP NPNT ZNF423 DAB2 THBS1 SMAD7 VEPH1 HES1 HTRA4 MIR17HG NRROS RBPJ MYO1C FLT1 ADAMTSL2 NOTCH1 SKIL FSTL3 SPRY4 UBB TGFB1 TGFB1I1 MYOCD TOB1 NPTN LTBP1 SMAD2 LDLRAD4 FGF2 EPN2 CDKN1C CREBBP ING2 SKI FGFR1 GRB10 SMAD4 SKOR1	down	**
GO_TELOMERE_ORGANIZATION	0.0012937	0.0263691	0.4550599	0.3660830	1.595107	131	NEK2 PRIM2 PIF1 POLE NABP2 AURKB CCT6A CCT2 EXO1 CCT5 POLA2 ATR POLD2 SMARCAL1 PRKDC XRCC1 BLM PML PARP1 TERC POLE2 CCT3 DNA2 FEN1 RECQL4 TEP1 TELO2 CCNE1 DCLRE1C SMG5 RAD51D FBXO4 POLD1 SLX4 CCT7 RAD50 YLPM1 RPA1 PRIM1 RTEL1 RFC5 RAD51 TNKS1BP1 SIRT6 PNKP APEX1 NAT10 EXOSC10 NHP2 DCLRE1B DCLRE1A POT1 XRCC5 CTC1 POLD3 XRCC6 ZBTB48 HNRNPA1 RFC3 POLE4 RFC4 HUS1B SRC MAPKAPK5 PCNA	up	*
GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION	0.0005248	0.0142434	0.4772708	-0.3054050	-1.591798	163	CD300LF FOXF1 HMOX1 SPN MNDA THBD PRKAR1A CD9 FGR ANXA1 SH2B3 FBXO7 HLX PAG1 GRN SFRP1 PDGFA IL10 NRARP DUSP3 SOCS5 PTPRC AXL ID2 SFTPD SMAD7 INHBA UBASH3B GNRH1 CD80 PDE5A TYROBP RC3H1 TBX21 CST7 TIGIT PELI1 RUNX3 CD74 MILR1 CYGB LRRC32 CD86 LGALS3	down	*
GO_MITOTIC_CELL_CYCLE	0.0000000	0.0000019	0.7477397	0.3130963	1.590844	876	HMGA2 CCNO MCIDAS TRIP13 FOXM1 CEP72 SPICE1 BRINP1 KIF20A CDC45 TICRR MCM10 CHEK2 BUB1B NEK2 CCNB1 CENPF STOX1 PBK KIF18B NDC80 PRIM2 BRCA1 TUBB2B TTK GINS1 CDK4 SMPD3 RACGAP1 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN POLE CNTD2 NABP2 STIL MSTO1 CEP70 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 TFDP2 CCNB2 RBBP8 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 PRC1 XRCC2 ORC1 CCNF DTL CIB1 MCM8 ZFYVE19 NCAPD2 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 WDR62 CASP2 MELK HMMR BTRC SMARCD3 DLG1 NLE1 KIF23 CEP55 FOXA1 MKI67 CUL9 BOD1 CUL7 KIF15 KNTC1 KIF3B BUB1 LGMN TOP2A MAP10 AURKA EME1 ODF2 POLA2 SFI1 TPR KIF2C MCM7 MAD1L1 CENPW POC1A CLSPN RRM2 TTLL12 CDCA5 PRKDC WDHD1 FSD1 TOM1L1 KIF11 GPSM2 MCM3 CDC25C SOX4 EGFR LIG1 EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 MDM2 DSCC1 PKMYT1 FBXL8 BLM PPP5C PML CNOT3 ERCC2 MNAT1 SPRY1 SKP2 RECQL5 PSRC1 PTPN3 INCENP KNSTRN CKS1B AFAP1L2 CDKN2C NUSAP1 ANAPC5 CTDSP2 CDK1 POLE2 CEP97 CENPJ RFWD3 BIRC5 GMNN DIS3L2 E2F1 NCAPG PSMB5 CCNJL TMEM8B DNA2 KIF2A ANAPC7 EZH2 CNOT11 SPAG5 EGF SAPCD2 MTBP PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP KPNB1 CEP63 CCNE1 CEP192 RHOC CDC23 CDK3 TUBG1 DLGAP5 CNOT2 PSMA5 NINL TACC3 RAD9A TUBB2A PSME2 KIF22 HIRA MTA3 TUBA8 AKAP8L FZR1 KIF20B ASNS ANAPC1 CDK13 PSMD2 JTB ATAD5 PPME1 CDC7 CENPK SH2B1 TADA3 CKAP5 PSMB3 CDC20 TUBG2 AAAS GBF1 EFHC1 BCL2L1 RPA1 CHMP4C WNT10B CDK5RAP2 MCM6 DNMT3A CHTF8 STAMBP CENPT PRMT1 CKAP2 MCM5 HAUS6 NEK4 TFAP4 AATF KATNB1 RTKN RCC1 CCNG1 HAUS4 PSMB4 ANK3 CEP152 PRMT5 ESRRB NUP62 CEP85 ALMS1 MSH2 CCNA2 PRIM1 BANF1 RTEL1 ANAPC2 TUBGCP4 CEP164 LPIN1 TUBA4B RAD51 GADD45GIP1 TNKS1BP1 ZWILCH FBXW11 CHMP1A	up	***
GO_LEUKOCYTE_CELL_CELL_ADHESION	0.0000362	0.0017652	0.5573322	-0.2813819	-1.586325	283	SIRPB1 PECAM1 ADTRP CD55 SPN IL1B FYN CD44 CAV1 PRKAR1A CDC42 TGFBR2 IL23A RHOA ANXA1 MIR146A CD5 ADA ITGA5 MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 TFRC ZMIZ1 IL10 NRARP DUSP3 PTAFR KLF4 ROCK1 CLECL1 SOCS5 FAM49B PTPRC SELL SELP JAM2 IGFBP2 SFTPD SMAD7 IL7R HES1 GNRH1 NCKAP1L CD80 IL6 CD160 ETS1 PDE5A RAC2 CCR7 PIK3R1 CD83 GRB2 MALT1 RC3H1 DOCK8 AP3B1 TBX21 TIGIT PELI1 RUNX3 CD74 CD1D ZBTB1 CD6 LRRC32 MIA3 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1 ICAM1 SELPLG IL18 RIPK2 NLRP3 HAVCR2 ADORA2A PAK2 KLRK1 TNFSF9 CD70 ZBTB16 CX3CR1 ICOS ITGAL ITGB1 S100A8 HAS2 NDFIP1 EFNB2 BCL10 HMGB1 CD3E IRF1 RC3H2 TNFRSF13C DUSP22 NR4A3 CD4 CASP3 NFKBIZ EBI3 CBFB PNP FERMT3 PYCARD	down	**
GO_SYNAPSE_ASSEMBLY	0.0025833	0.0420217	0.4317077	0.3718860	1.586030	114	DKK1 EPHB3 GABRB3 SIX4 SDK2 COLQ PCLO SIX1 SLITRK5 EFNA5 EPHB1 PPP1R9A CLSTN3 TPBG CEL SDK1 OXTR SLITRK6 DLG5 DNER GABRB2 LRRC4 GNPAT ADNP LRFN3 EPHB2 SPTBN2 MDGA1 NRXN2 UBE2V2 BSN MUSK CDH1 DBNL NLGN2 CDK5 NTN1 EIF4G1 FBXO45 NLGN1 PLXNB1 GRIN1	up	*
GO_MICROTUBULE_BINDING	0.0004551	0.0126702	0.4984931	0.3434568	1.585649	210	KIF1A KIF12 KLC3 KIF20A MDM1 KIF18B RACGAP1 KIF14 PLK1 GAPDH PRC1 DYNC1I1 KIF27 WDR90 KIF23 KIF15 KIF3B MAP10 KIF2C MAP1LC3C FSD1 HOOK1 KIF11 GAS8 KIF3C CLIP3 SPAG8 PPP5C TRPV4 PSRC1 NUSAP1 KIF5A BIRC5 JAKMIP1 KIF19 KIF2A KIF7 CCDC88C SPAG5 MAST1 SPEF1 VPS41 KIF22 DNM1 KIF21A GAS2 S100A9 MAP6D1 KIF20B POLB TRAF3IP1 FTCD CDK5RAP2 KIF21B EML6 FAM161A KATNB1 SKAP1 HAUS4 NEFH STRBP ALMS1 APC2 JAKMIP3 TUBGCP4 SYBU CCDC181 HOOK2 CCDC88B MARK4 CAMSAP3 CENPE MAP1LC3A GOLGA2 DCDC1 MAP9 DNM1L CLASP1 KIF24	up	*
GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS	0.0000000	0.0000002	0.8012156	-0.2609417	-1.583335	744	SLC6A4 TNR SMAD6 LIMS2 ANGPT4 DAB1 RBP4 SEMA6B SEMA3G SEMA6A EREG ACVRL1 SOSTDC1 TEK EDNRB DENND5A TAL1 KLF13 PPARG HHEX TBX3 GATA2 IL1B TIE1 WNT4 RAPGEF2 BMP2 INSIG1 FIG4 BDNF ARHGEF15 ECSCR SOX17 DDX6 CAV1 CORO1C BMPR2 GTF2I CTDSP1 TBXA2R FGF10 MIR27B GAS6 TGFBR2 NFATC3 TRIB1 LILRB3 HSPG2 RHOA SEMA6D ANXA1 TBX2 WWC2 MIR146A MYOZ1 MMRN2 FBXO7 ASAP1 PTPRM SEMA3B FOXA2 ABCG1 PAQR3 HLX ADIPOR1 EIF4E ADRB1 GATA3 PPP3CA RB1 RGCC ADRB2 NFE2L2 SFRP1 AKT3 SPRY2 WNT3A ZEB1 SRGN ARHGEF2 HNRNPU ZNF365 FOXC2 NODAL CST3 LRP4 GPR4 ROCK2 SNAI1 NRARP FOXO1 PTPRO TRIM46 DAAM2 YBX3 KLF4 RUNX1T1 REST ID3 ROCK1 ZADH2 THBS1 ARNTL ADAMTS9 SOCS2 CLDN5 SOCS5 KLF7 CCL3 CDKN1A PDE3B VIM HOPX ID2 TLR4 MIR24-2 LBH SMAD7 INHBA PINK1 TBX5 ZNF706 UBASH3B PAFAH1B1 RUFY3 HES1 MIR17HG AKIRIN1 KREMEN1 ARHGDIB TGFB2 GNRH1 SRGAP2C KANK1 MYLIP RBPJ WNT9A IL17D ID4 CNTF PPP2CA AREG IL6 YBX1 CD160 MED28 PSEN1 VAT1 NOTCH1 LIMD1 GABPA CUL4A CTSZ CNTN4 BAG5 SKIL IFRD1 PIK3R1 LSM1 NPR1 RC3H1 RTN4R PRKACA TRAK2 FSTL3 TBX21	down	***
GO_CELL_PROJECTION_ASSEMBLY	0.0000042	0.0003070	0.6105269	0.3216199	1.583242	465	CCNO PKHD1 MCIDAS ONECUT2 ONECUT1 CCL19 CEP72 CEP89 RPGRIP1L ZMYND8 NEK2 AVIL NUDCD3 RAB3IP MKS1 CCDC113 STK36 IFT122 RHOV SPAG17 ANLN TENM2 TTC26 CEP70 PLK1 IFT27 KIF27 DCTN2 WDR90 EPS8L1 DNAI1 HAUS5 CEP250 RSPH1 PPP1R9A ARMC4 GOLPH3 BBS1 SPAG16 F2RL1 FOXJ1 TSGA10 KIF3B CCDC13 FBF1 MYO10 ODF2 SFI1 IFT43 CD2AP POC1A HYDIN TEKT2 WNT1 CCDC114 DCDC2 PFN2 WDR60 NME5 DNAH8 SLC9A3R1 CDC42EP1 IFT172 GAS8 KIF3C CBY1 DNAAF3 RABEP2 C2CD3 CCDC40 MYO1A TNIK DRC1 LRGUK LRRC6 IQCB1 CDK1 CROCC CEP97 CENPJ VANGL2 TCTN2 SSX2IP DYNLL2 POC1B DNAH5 TMEM231 FGFR1OP IFT52 CEP63 BBS5 PLEKHM1 CEP192 NPHP1 TUBG1 DNAH7 CCL21 MTOR NINL MNS1 CCDC151 IQCG TMEM237 SPAG1 TEKT3 TWF1 NUP85 TRAF3IP1 DNAJB13 SH2B1 C15orf62 CKAP5 IQUB PLD1 WDR34 TTLL3 TCTN1 CDK5RAP2 ODF2L PLEK2 DNAI2 WDR35 HAUS6 DYNC2H1 FAM161A TBC1D30 PIP5K1A HAUS4 RSPH4A NEFH TCHP UNC119B CEP152 TMEM17 B9D1 ALMS1 DBNL MIEN1 ICK CEP164 CLUAP1 DNAH1 MARK4 CELSR2 CTTN TBC1D32 TTC39C VDAC3 NTN1 BCAS3 RHOD UBXN10 CELSR3 ESPN SYNE2 TRPM2 TTC30B ZMYND10 NLGN1 CLASP1 KIF24 LPAR3 KIAA0586 CEP290 ARMC2 DNAAF1 INPPL1 DYNC1H1 MAK TEKT1 ABLIM3 WRAP73 WDR63 PLK4 HRAS FAM110C AKAP9 PCNT	up	***
GO_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING	0.0010811	0.0232105	0.4550599	-0.3159609	-1.579992	125	RAMP3 EDNRB LHCGR ADCY9 GPR65 ADCY4 RAPGEF2 RAMP2 CALCRL ADRA1D ADCYAP1R1 TBXA2R PRKAR1A RXFP1 PDE2A CD36 RAPGEF4 PEX5L ADRB1 ADRB2 PDE4D PTGIR THBS1 PDE3B PTGER3 UBE2B GNAQ GNAI2 PTH1R S1PR4 ADCY2 GPR61 ADRA1A PTGER4 PTGER2 NPR1	down	*
GO_LEUKOCYTE_CHEMOTAXIS	0.0003406	0.0100035	0.4984931	-0.3028081	-1.578121	171	CXCL3 IL1A SWAP70 CXCL16 EDNRB IL1B CCL3L1 C5AR1 S1PR1 IL1RN GAS6 IL23A ANXA1 PLA2G7 SBDS ADAM17 JAM3 PDE4D IL10 CCL22 PTPRO BST1 THBS1 CCL3 CXCL2 CCL4 SFTPD XCL2 FCER1G DUSP1 OXSR1 AKIRIN1 TGFB2 NCKAP1L FLT1 IL6 HRH1 RAC2 CCR7 DAPK2 GPR183 CXCL5 CD74 VAV3 ITGA9 FPR2 LGALS3 KLRC4-KLRK1 CCR1 GPR18 ADAM10 PDE4B CCL20 CCR6 CXCR4 KIT EDN1 KLRK1 MTUS1 LYST IL16 ANO6 GREM1 SERPINE1 C5AR2 CNR2 C5 S100A8 PIK3CG CALR WNT5A	down	*
GO_HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES	0.0000001	0.0000160	0.6901325	0.3126838	1.575671	709	KIF1A KIF12 ABCA13 KLC3 DDX11 ENTPD2 ABCC2 HELLS KIF20A DDX12P RUVBL1 CDC45 DNAH2 MYO3B POLQ KIF18B TTF2 MYH16 PIF1 TUBB2B GINS1 KIF14 RHOV ABCA12 GMPS PMS2P5 IFT27 RGS6 FIGNL1 THTPA MCM4 RAB36 MCM2 RAD54B DNAH3 PMS2 XRCC2 DYNC1I1 MCM8 GINS4 KIF27 MYL6B DNAH14 DCTN2 DNAI1 RUVBL2 TNNT2 NUDT1 KIF23 RND2 HLTF KIF15 KIF3B TOP2A MYO10 RAB19 GTPBP3 SMARCAL1 KIF2C MCM7 WDR78 ABCC5 RHOBTB3 HELB RAD54L ENTPD6 KIF11 MCM3 PEX6 PFN2 NUDT17 WDR60 CHD6 DNAH8 MORC2 ABCB6 KIF3C RAB13 DCTPP1 ABCB9 DSCC1 DNAH11 BRIP1 EEFSEC BLM MTG1 RGS4 ERCC2 MNAT1 ENTPD5 MYO1A RECQL5 DDX56 NSF DDX51 DNAH6 KIF5A GBP3 NUDT2 NAV2 DHX37 ABCC11 KIF19 DNA2 KIF2A DHX33 ENPP3 KIF7 DYNLL2 MYO5B RAB6B DNAH5 ABCA4 PSMC4 RECQL4 GBP5 EFTUD2 DHX34 MYO19 MOV10 ARFRP1 RHOC TUBG1 RGS17 RABL2A DNAH7 DHX40 FHIT LONP1 TUBB2A TUBA3D KIF22 RAD51D ARF5 DNM1 TUBA8 CHTF18 GBP6 KIF21A GINS2 NUDT16 KIF20B GFM2 CHD5 GNAZ ENPP2 ATAD5 RAB24 ATP13A1 RAD50 ABCC10 KLC2 KLC4 EP400 LSG1 ABCC9 ENTPD8 WDR34 TUBG2 ENTPD3 ABCC3 ABCA7 FANCM MCM6 CHTF8 MYO5C WRNIP1 DYNC1LI2 KIF21B DHX8 MCM5 DNAI2 GNG4 RAB15 ZRANB3 DDX23 DYNC2H1 RAB3D KATNB1 DOLPP1 MYH7B IGHMBP2 RHOBTB1 MYH3 RAP2B ABCD4 LHPP DDX55 ATAD2 TSR1 RAB34 GNAL MYH13 PMS2P1 MSH4 PMS1 MSH2 SMARCA4 DCPS DDX54 ABCF3 RTEL1 CANT1 RFC5 NUGGC GBP1 GTPBP2 ABCF2 DNAH1 TUBA4B BMS1 RAD51 ARHGAP5 GBP2 SNRNP200 CHD3 GNA14 RHOT2 GNA12 RAB43 RNF213 CENPE RHOD SRCAP MYO15A DDX52 HSPA7 CGN	up	***
GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY	0.0005934	0.0153789	0.4772708	-0.3044289	-1.574041	159	SMAD6 ACVRL1 CDH5 ENG FOLR1 CAV1 CITED2 TGFBR3 CBL TGFBR2 RHOA LTBP4 ADAM17 NLK CAV2 ZEB1 NODAL PRDM16 SDCBP NPNT DAB2 THBS1 CLDN5 SMAD7 VEPH1 HTRA4 MIR17HG TGFB2 NRROS ADAMTSL2 APPL1 JUN LTBP2 FERMT2 SKIL CREB1 FOS UBB TGFB1 PARD6A ZFYVE9 TGFB1I1 LRRC32 MYOCD LTBP1 SMAD2 LDLRAD4 ARRB2 CDKN1C CREBBP ING2 SKI LTBP3	down	*
GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	0.0007551	0.0182190	0.4772708	0.3478060	1.573146	177	HMGA2 DDX11 FOXM1 EYA1 PARPBP CHEK2 EYA2 TIMELESS POLQ BRCA1 NPAS2 WDR70 FIGNL1 MAGEF1 TP53BP1 EEF1E1 AUNIP ATR MSX1 SMYD2 PRKDC HELB EGFR CHEK1 RAD51AP1 XRCC1 MDM2 PML PLA2R1 RECQL5 PARP1 RFWD3 MAD2L2 RAD9A FBXO4 MGMT NUDT16 TRIM32 BCL2L12 ATAD5 PARP9 UBQLN4 TWIST1 BCL2L1 UBE2V2 THOC5 WRNIP1 ANKRD1 UIMC1 NEK4 DTX3L RTEL1 RAD51 EYA4 PAXIP1 NUDT16L1 WDR76 SIRT6 PARG TP53 MUC1 PIAS4 TMEM161A	up	*
GO_LEUKOCYTE_PROLIFERATION	0.0000811	0.0032861	0.5384341	-0.2841202	-1.572444	231	ACE CD55 HHEX GAPT SPN IL1B MNDA WNT4 FYN FGF10 PRKAR1A CD22 SLC11A1 TGFBR2 IL23A ANXA1 CLCF1 ADA MS4A1 IFNK TRAF6 WNT3A MAPK8IP1 TFRC IL10 BST1 CLECL1 MPL NPR3 CDKN1A PTPRC TLR4 IGFBP2 SFTPD IL7R HES1 GNRH1 NCKAP1L CD80 IL6 PDE5A RAC2 TYROBP GPR183 MALT1 RC3H1 DOCK8 CD151 PELI1 AZI2 CD74 VAV3 CD1D CD6 LRRC32 CD86 IRS2 CD81 LGALS3	down	**
GO_REGULATION_OF_CELL_SHAPE	0.0009196	0.0209882	0.4772708	-0.3078483	-1.571692	138	DLC1 FGD5 P2RY1 RDX FYN BAIAP2 CDC42EP2 CDC42 EPB41L3 FGR RHOA ANXA1 PLXNA2 PLXNA4 CRK ATP10A RHOB PARVB FMNL3 CCL3 WASF3 ZMPSTE24 HEXB HCK FMNL2 RHOBTB2 LIMD1 RAC2 RHOG RHOJ PALM FERMT2 PALMD RHOQ EPB42 GNA13 ICAM1 WDR1 SEMA4A CDC42EP3 ARHGAP18 BRWD1 RND1 PARVA KIT	down	*
GO_EPITHELIAL_CELL_APOPTOTIC_PROCESS	0.0029153	0.0459462	0.4317077	-0.3326670	-1.571652	86	HMOX1 TEK GATA2 SFRP4 RAMP2 ECSCR BMPR2 GAS6 TGFBR2 GATA3 RB1 RGCC NFE2L2 TCF7L2 IL10 THBS1 MIR24-2 WFS1 IL6 CD160 NDNF SRSF6 SPOP SORT1 ICAM1 ARRB2 BOK STK4 ANO6 SERPINE1 HIPK1 ZFP36 PIK3CG	down	*
GO_SMOOTH_MUSCLE_CELL_PROLIFERATION	0.0014995	0.0292793	0.4550599	-0.3154107	-1.568139	121	EREG HMOX1 PPARG CALCRL CDH13 S1PR1 HMGCR MIR27B TGFBR2 TRIB1 APOD HBEGF FOXP1 TRAF6 TCF7L2 CNN1 IL10 PTGIR PTAFR KLF4 THBS1 NPR3 ABCC4 CDKN1A ID2 GNAI2 IL6 JUN NPR1 SOD2 NQO2 MYOCD FGF2 IL18 SF1 EDN1 FOXJ2 PTEN PRKG1	down	*
GO_MUSCLE_STRUCTURE_DEVELOPMENT	0.0000002	0.0000221	0.6901325	-0.2641577	-1.567621	514	RBP4 EPAS1 EREG SOSTDC1 FOXF1 PDLIM2 EDNRB CCM2L TBX3 WNT4 RAMP2 BMP2 SIK1 ENG BDNF EGR2 TMOD3 CAV1 QKI GPCPD1 S1PR1 HMGCR FGF10 PRKAR1A MEF2A CDC42 TGFBR3 CD9 TGFBR2 NFATC3 HEG1 RHOA KCNAB1 JPH2 TBX2 MYOZ1 HBEGF CACNA2D2 LMNA CSRP1 TMEM204 BTG2 CAV2 HLX PPP3CA RBM4 RB1 WNT3A ZEB1 HNRNPU TCAP TCF7L2 SGCA SETD3 FOXC2 ADARB1 UNC45B TNNC1 NPNT BNIP2 YBX3 REST ID3 PLEKHM3 USP2 ARNTL CDK9 SPAG9 NR1D2 ATF3 MIR24-2 CD53 SMAD7 ZMPSTE24 TBX5 VAMP5 CYP26B1 MYH11 HES1 MAFF MIR17HG AKIRIN1 TANC1 TGFB2 LMOD3 PIAS1 MTPN SRF BTG1 RBPJ SLC8A1 CNTF TMOD1 YBX1 MED28 COPS2 UTRN NOTCH1 ADRA1A JPH1 DDX17 FOXN2 EPC1 IFRD1 DDX5 CREB1 HOMER1 ITGA11 FOS CACYBP CD164 EHD2 FLNC SYPL2 SORT1 SAV1 TGFB1 EHD1 MIR23A PDLIM1 PIM1 CD81 SOD2 MEIS1 MYOCD GATA6 ACTN2 RGS2 PRICKLE4 TAGLN MBNL1 RXRA FGF2 IL18 PDLIM5 FKBP1A WDR1 LMOD1 ARRB2	down	***
GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS	0.0000000	0.0000001	0.8140358	-0.2534657	-1.566946	882	TRIM71 ANGPT4 SLC24A4 RBP4 EPAS1 CLEC1B SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK DLC1 TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 DCSTAMP WNT4 EMP2 BMPER RAMP2 PTPRB BMP2 CDH5 ENG FIG4 FOLR1 EGR2 TMOD3 ECSCR SOX17 WDR74 CAV1 CITED2 CALCRL CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 PRKAR1A MEF2A CDC42 MIR27B TGFBR3 CD9 AGTPBP1 EPB41L3 TGFBR2 HSPG2 CASP9 RHOA ZEB2 APOD CD36 ANXA1 TBX2 MIR146A MYOZ1 MMRN2 PTPRM ADA FOXA2 ADAM17 WNT2B PLXNA2 CSRP1 ITGA5 CLEC14A HSPB1 LUZP1 ANPEP GATA3 NR4A1 JAM3 RGCC TRAF6 NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A SOX7 TCAP MTHFR PDGFA FOXC2 NODAL RHOB HIF3A GPR4 IL10 ROCK2 AMOTL1 SNAI1 NRARP FOXO1 TBX4 TNFSF12 TSPAN12 KLF4 ROCK1 VASP THBS1 ADAMTS9 CLDN5 MPL CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HOPX HPSE MIR24-2 RECK CD53 PIK3C2A ELK3 INHBA ADIPOR2 TBX5 SH2D2A PEF1 MYH11 PAFAH1B1 NUS1 PTGIS DCHS1 HES1 PLCD1 ANXA3 TANC1 TGFB2 MMP19 LMOD3 TOPORS MTPN SRF BTG1 PRCP RBPJ HESX1 FLT1 TMOD1 IL6 WASF2 PKNOX1 CD160 PSEN1 PIKFYVE NDNF JUN NOTCH1 GABPA ETS1 TYROBP JUNB JAK1 RHOJ PODXL SKIL SP3 ACKR3 HERC1 GRB2 KBTBD8 NPR1 RC3H1 PRKACA MCAM CD34 AGFG1 POGLUT1 RRAS KLF2 EHD2 WNT11 TGFB1 EHD1 VAV3 ISM1 JMJD6 MTMR2 MIR23A MMP15 MIA3 PIM1 CNTNAP1 COL15A1 CD81 MEIS1 CLASP2 GATA6 MFNG GNA13 ACTN2 CALB1 ETS2 SMAD2 ELF5 UNC13D FGF2 IL18 FKBP1A VASH1 WDR1 EGFL7 EPB41L5 LMOD1 EPN2 OSR1 SEMA4A RTN4 CXCR4 TMOD2 PTCH1 SP100 EPHA2 PARVA GLUL STK4 CUL3 RET RAPGEF3 EDN1 ETV2 FOXJ2 PTEN SKI SYNPO2L FGFR1 RORA NRP2	down	***
GO_HISTONE_BINDING	0.0022413	0.0380455	0.4317077	0.3483231	1.565693	164	HJURP ZMYND8 L3MBTL1 UHRF1 MCM2 NCAPD2 SMARCC1 TP53BP1 TTLL12 CHAF1B YEATS2 BRD9 PIH1D1 PRMT6 IPO9 CKS1B NCAPG2 CBX5 ASF1B ING4 WDR5B NPM3 VPS72 TRIM24 SSRP1 ANP32E NOC2L LRWD1 PRMT7 CHD5 PARP9 BAZ2A SUPT16H L3MBTL2 PWWP2A UIMC1 PYGO2 RCC1 SMARCC2 ATAD2 SMARCA4 DTX3L MLLT6 BCAS3 TONSL SRCAP SBNO2 KDM5B NCAPD3 PWP1 SART3 MBTD1 SPHK2 RAG1 NPM1 CHD8 RNF8 MSH6 MLLT3 WDR5 CXXC1 USP49 MTF2 BRD4 KMT2D SAP30L	up	*
GO_CELL_CYCLE_PROCESS	0.0000000	0.0000004	0.7881868	0.3047964	1.564721	1131	HMGA2 CCNO PKHD1 TRIP13 DDX11 FOXM1 CEP72 SPICE1 BRINP1 KIF20A MDM1 DDX12P STAG3L2 CDC45 TICRR MCM10 CHEK2 BUB1B NEK2 CCNB1 SOX2 CENPF TIMELESS PAGR1 STOX1 MND1 KIF18B NDC80 PRIM2 TBRG4 BRCA1 PHGDH TTK GINS1 CDK4 SMPD3 RACGAP1 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN POLE CNTD2 ASPM NABP2 STIL MSTO1 CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 TFDP2 CCNB2 FIGNL1 RBBP8 MCM4 PRKCA CYP27B1 MCM2 RAD54B TYMS CDC25A MYBL2 PRC1 XRCC2 ORC1 NOX5 CCNF DTL TDRKH MCM8 MAP2K6 ZFYVE19 NCAPD2 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 WDR62 CASP2 MELK HMMR BTRC SMARCD3 DLG1 KIF23 CEP55 STAG3 MKI67 CUL9 BOD1 CUL7 FBXO43 KNTC1 RHNO1 KIF3B BUB1 FANCA MSX2 AUNIP TOP2A MAP10 GPER1 AURKA EME1 CBX3 REC8 ODF2 POLA2 SYCP2 POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 MSX1 CENPW POC1A CLSPN CXCR5 IL12B RRM2 CDCA5 PRKDC FSD1 NSUN2 RAD54L TOM1L1 KIF11 FANCD2 GPSM2 MCM3 HORMAD1 CDC25C SOX4 EGFR LIG1 EME2 TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 MDM2 AKT2 DSCC1 MGA PKMYT1 BRIP1 FBXL8 BLM PML C2CD3 CNOT3 ERCC2 MNAT1 STXBP4 SPRY1 SLC39A5 SKP2 RECQL5 PSRC1 INCENP KNSTRN CKS1B CDKN2C NUSAP1 CBX5 ANAPC5 ING4 CTDSP2 CDK1 CROCC POLE2 CEP97 CENPJ RFWD3 BIRC5 KIAA0753 GMNN SUN1 DIS3L2 E2F1 NCAPG PSMB5 CCNJL DNA2 KIF2A ANAPC7 FEN1 SSX2IP EZH2 CNOT11 SPAG5 EGF RAB11FIP4 SAPCD2 TRAPPC12 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP STK11 IRF6 KPNB1 GIPC1 MYO19 ANKK1 CEP63 CCNE1 CEP192 RHOC CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 MTOR NINL TACC3 RAD9A LLGL2 PSME2 KIF22 HIRA RAD51D MTA3 TRIM37 MYBBP1A CENPQ AKAP8L ESCO2 GAS2 FZR1 PKP4 NUDT16 CGREF1 KIF20B LAMTOR2 SGSM3 ANAPC1 SND1 CDK13 POLD1 PSMD2 JTB ATAD5 PPME1 SLX4 CDC7 RAD50 ANKRD31 CENPK SASS6 KLHDC3 SH2B1 STAG3L4 CENPV MEI1 CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B ROPN1B TUBG2 AAAS EFHC1 ALKBH4 BCL2L1 RPA1 CHMP4C WNT10B FANCM CDK5RAP2 MCM6 CHTF8	up	***
GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE	0.0029619	0.0466088	0.4317077	0.3638181	1.564342	119	FOXM1 CHEK2 CCNB1 BRCA1 E2F8 GTSE1 PLK1 TFDP2 ACER2 DTL CASP2 EEF1E1 AURKA ATR MSX1 SMYD2 PRKDC WNT1 CDC25C SOX4 CHEK1 MDM2 PML CNOT3 PLA2R1 ING4 CDK1 E2F1 CNOT11 MAD2L2 CEP63 CNOT2 FZR1 ATAD5 TWIST1 PRMT1 ANKRD1 UIMC1 TFAP4	up	*
GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS	0.0016284	0.0309525	0.4550599	0.3502776	1.563481	158	CPS1 GPT GPT2 BHMT ACMSD PSPH NOXRED1 SLC25A21 PHGDH GMPS ALDH18A1 GLDC PAH SHMT2 GFPT1 IDO1 GCAT MCCC2 PYCR2 ASS1 AHCY CAD TST PLOD2 GOT2 OAT PSAT1 HYKK FAH ALDH7A1 ASNS MAT1A NAGS PFAS HPD FTCD SIRT4 PHYKPL ASRGL1 HIBADH PRODH AMT GAD1 DDAH1 PYCR1 AGMAT NOS1 MTHFD1 SEPHS1 PCBD1 BCAT2 ACAD8 SARDH NOS3 HGD ASL MPST PLOD1 GCSH MTR SHMT1 MTRR NIT2 PLOD3 AFMID MCCC1 HAL CARNS1 HAAO	up	*
GO_REGENERATION	0.0007632	0.0183265	0.4772708	-0.3019277	-1.563136	152	TNR HMOX1 PPARG FOLR1 C5AR1 FGF10 TGFBR3 CD9 GAS6 TGFBR2 SCARF1 APOD ANXA1 MYOZ1 RAP1A LCP1 PPP3CA JAM3 NDEL1 GRN SGCA PTPN12 IL10 SRSF5 KLF4 CDKN1A AXL MATN2 ANXA3 AKIRIN1 KREMEN1 STK24 MTPN NINJ1 CNTF LAMB2 JUN NOTCH1 IFRD1 RTN4R	down	*
GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE	0.0007668	0.0183268	0.4772708	-0.2997584	-1.560781	166	FFAR4 SIGLEC11 GPR17 ACP5 FOXF1 TEK PPARG WFDC1 CDH5 SAMHD1 CLEC12B CALCRL APOD MIR146A ADA RNF125 SERPINB9 GATA3 SIRPA RB1 GRN CRK IL10 MEFV KLF4 SOCS5 NFKB1 NR1D2 PTPRC PTGIS SOCS3 SEC14L1 PSMA1 ETS1 PTGER4 CST7 YTHDF3 TREX1 CR1 SMPDL3B FPR2 YTHDF2 NLRP6 CNOT7 SYT11 ARRB2 NLRP3 HAVCR2 ADORA2A RORA ITCH LDLR	down	*
GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS	0.0002382	0.0077358	0.5188481	-0.2858657	-1.558182	208	EPAS1 HMOX1 TAL1 KLF13 GAPT GATA2 LIPA HCAR2 TMOD3 TGFBR3 ANXA1 SH2B3 ADA ADAM17 SLC7A11 GATA3 JAM3 RB1 SPI1 SLC46A2 MPL AXL ID2 FCER1G WDR48 LYAR INHBA ILDR2 IL7R MIR17HG ADD1 SRF NCKAP1L IL6 PKNOX1 NOTCH1 ETS1 HSPA1B DNASE2 CCR7 SKIL SP3 GPR183 GCNT4 RC3H1 RASSF2 RRN3 KLF2 FOXO3 CD74 CCR4 EPB42 JMJD6	down	**
GO_TRANSLATIONAL_ELONGATION	0.0027425	0.0439063	0.4317077	0.3608587	1.554541	120	TSFM MRPL46 DIO2 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 EEFSEC MRPS30 MRPL36 MRPL37 MRPS2 MRPL17 DPH7 MRPS12 MRPS34 MRPL11 MRPL52 DPH2 MRPL4 DAP3 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 DPH5 MRPL14 MRPS25 MRPL55 GTPBP2 GADD45GIP1 MRPL9 SRP9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 MRPS16 MRPL12 ZNF598 MRPL43 MRPL2 MRPS6 ABTB1 EEF1D MRPS7 EEF2K MRPL35 MRPL13 MRPL33	up	*
GO_LEUKOCYTE_MIGRATION	0.0000067	0.0004543	0.6105269	-0.2665804	-1.553498	395	ANGPT4 CXCL3 IL1A HMOX1 SWAP70 TEK CXCL16 GCSAML OLR1 GPR15 EDNRB PECAM1 ADTRP SPN IL1B THBD FYN CD44 CCL3L1 CAV1 ESAM C5AR1 S1PR1 CDC42 CD9 IL1RN GAS6 IL23A RHOA APOD ANXA1 PLA2G7 IGKV2-28 ADA SLC7A7 SBDS ADAM17 ITGA5 SLC7A11 GATA3 JAM3 SIRPA CRK PDE4D CD58 IL10 CCL22 PTPRO BST1 PTAFR FUT7 ROCK1 SLC7A8 THBS1 CCL3 ITGAX CXCL2 SELL SELP CCL4 JAM2 MIR24-2 SFTPD XCL2 FCER1G DUSP1 OXSR1 AKIRIN1 TGFB2 HCK NCKAP1L IGLV2-11 FLT1 IL6 CD48 LRCH1 HRH1 RAC2 TREM1 RHOG PTGER4 CCR7 DAPK2 PIK3R1 GYPC GRB2 GPR183 DOCK8 CXCL5 TNFRSF10B TBX21 IGKV3-20 CD34 SLC3A2 CD74 TGFB1 VAV3 ITGA9 VPREB3 FPR2 MIA3 CD81 LGALS3 DOK2 KLRC4-KLRK1 IGHV3-23 CCR1 GPR18 ADAM10 PDE4B IGKV1D-39 CCL20 CCR6 ICAM1 SELPLG	down	***
GO_REGULATION_OF_CHEMOTAXIS	0.0005257	0.0142434	0.4772708	-0.2957718	-1.553408	178	SEMA6B SEMA3G SEMA6A SWAP70 CDH13 BMPR2 C5AR1 S1PR1 FGF10 GAS6 IL23A SEMA6D PLA2G7 SEMA3B ADAM17 HSPB1 JAM3 PLXNA4 WNT3A DUSP3 PTPRO BST1 ZSWIM6 THBS1 STX3 CCL3 CCL4 XCL2 DUSP1 OXSR1 AKIRIN1 NCKAP1L IL6 NOTCH1 RAC2 CCR7 DAPK2 GPR183 SUCNR1 PPM1F CD74 CCR4 TGFB1 FPR2 KLRC4-KLRK1 CCR1 GPR18 ADAM10 CCR6 FGF2 SEMA4A TIAM1 CXCR4 EDN1 KLRK1 MTUS1 FGFR1 IL16 ANO6 GREM1 SERPINE1 C5AR2 C5 TREM2 EFNB2 CALR WNT5A ANGPT2 HMGB1	down	*
GO_T_CELL_ACTIVATION	0.0000060	0.0004174	0.6105269	-0.2669899	-1.549477	390	SIRPB1 CD55 SPN IL1B WNT4 FYN CD44 CAV1 PRKAR1A CDC42 CD1C SLC11A1 TGFBR2 IL23A CD8A RHOA ANXA1 CD5 ADA ADAM17 CLEC7A MAP3K8 FOXP1 HLX PAG1 LCP1 IFNK GATA3 PPP3CA SIRPA IL18R1 TRAF6 ZEB1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 SLC46A2 FUT7 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SFTPD FCER1G SMAD7 IL7R CYP26B1 HES1 GNRH1 SRF NCKAP1L CD8B CD80 IL6 PKNOX1 CD160 PSEN1 PDE5A RAC2 PTGER4 CCR7 SP3 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 DOCK8 AP3B1 CD7 TBX21 ZNF683 TIGIT CD151 PELI1 AZI2 RUNX3 TREX1 CD74 CR1 CD1D ZBTB1 JMJD6 CD6 LRRC32 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1 GPR18 CCR6 ICAM1 IL18 LAT FKBP1A SEMA4A RIPK2 NLRP3 CCR9 HAVCR2 ADORA2A KIT CD3G PAK2 KLRK1 TNFSF9 RORA CCND3	down	***
GO_CARDIOCYTE_DIFFERENTIATION	0.0022807	0.0385217	0.4317077	-0.3101789	-1.549029	122	SOX18 TBX3 BMP2 SIK1 FOLR1 SOX17 MEF2A TGFBR3 TBX2 LMNA WNT3A HNRNPU TCAP REST MIR24-2 ZMPSTE24 TBX5 MYH11 HES1 TGFB2 SRF RBPJ SLC8A1 NOTCH1 ADRA1A CACYBP TGFB1 MIR23A MYOCD GATA6 ACTN2 RGS2 RXRA PDLIM5 ARRB2 EDN1 NRG1 SMAD4 GREM1 MAPK1 MYH10 ITGB1 EFNB2 CALR	down	*
GO_REGULATION_OF_PROTEIN_AUTOUBIQUITINATION	0.0007450	0.0181062	0.4772708	-0.9894301	-1.547906	2	SASH1	down	*
GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION	0.0002509	0.0080074	0.4984931	-0.2823350	-1.547323	220	SIRPB1 CD55 IL1B FYN CD44 CAV1 CITED2 CDC42 TGFBR2 IL23A RHOA ANXA1 CD5 ADA FOXA2 MAP3K8 HLX GATA3 SIRPA TRAF6 WNT3A TFRC NODAL ZMIZ1 IL10 DENND6A PTAFR CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SMAD7 IL7R HES1 NCKAP1L CD80 IL6 CD160 ETS1 PODXL CCR7 PIK3R1 CD83 GRB2 MALT1 DOCK8 AP3B1 FSTL3 RUNX3 CD74 CD1D ZBTB1 CD6 CD86 PDCD1 CD81 KLRC4-KLRK1 ICAM1 IL18 RIPK2 NLRP3 HAVCR2 PAK2 KLRK1 TNFSF9 PIEZO1 CD70 ZBTB16 ICOS HAS2 EFNB2 WNT5A BCL10 HMGB1 CD3E TNFRSF13C ITGA6 PDPN NR4A3 CD4 NFKBIZ EBI3 CBFB PNP ADAM19 PYCARD	down	**
GO_TUBE_DEVELOPMENT	0.0000000	0.0000002	0.8012156	-0.2508554	-1.546997	857	SMAD6 TRIM71 ANGPT4 DAB1 RBP4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SOSTDC1 SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK DLC1 EDNRB TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 CAT WNT4 EMP2 RAPGEF2 BMPER LIPA RAMP2 PTPRB BMP2 CDH5 ENG FOLR1 ECSCR SOX17 CAV1 CITED2 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 HSPG2 HEG1 RHOA ZEB2 APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM ADA WNT2B RAP1A PLXNA2 ITGA5 CLEC14A HSPB1 LUZP1 FZD4 FOXP1 ANPEP HLX SLC7A11 EIF4E GATA3 NR4A1 JAM3 RB1 RGCC TRAF6 NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A ZEB1 SPI1 TCAP MTHFR PDGFA TMEM38B FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 ROCK2 AMOTL1 NRARP TBX4 NPNT TNFSF12 TSPAN12 KLF4 ROCK1 VASP THBS1 ADAMTS9 CEBPA CLDN5 CLIC4 SEC24B ITPK1 FMNL3 CDKN1A PDE3B ITGAX EPGN HPSE ID2 MIR24-2 RECK SFTPD PIK3C2A ELK3 WDR48 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS DCHS1 HES1 MIR17HG PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ GZF1 HESX1 FLT1 AREG IL6 WASF2 PKNOX1 CD160 PSEN1 ADAMTSL2 NDNF HECA JUN NOTCH1 ETS1 CTSZ JUNB JAK1 RHOJ PODXL ATXN1L SP3 ACKR3	down	***
GO_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION	0.0002218	0.0073806	0.5188481	-0.2838628	-1.546743	211	SWAP70 DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 TMOD3 INPP5K BAG4 KANK3 MYADM BAIAP2 CDC42EP2 ESAM S1PR1 CDC42 CIT RHOA SPIRE1 RGCC SFRP1 SPTBN1 SORBS3 ROCK2 SYNPO ROCK1 VASP COTL1 C9orf72 ACTR3 CAPZA2 PLEK DSTN ADD1 ACTR2 LMOD3 HCK MTPN NCKAP1L KANK1 MYO1C TMOD1 WASF2 SYNPO2 ARHGEF10 PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 PPM1F SNX9 WNT11 WHAMMP3 CLASP2 ACTN2 ICAM1 ARPC2 WDR1 LMOD1 CDC42EP3 TMOD2 ARHGAP18 LIMCH1 RAPGEF3 ARPC5 SYNPO2L	down	**
GO_REGULATION_OF_INFLAMMATORY_RESPONSE	0.0000545	0.0024245	0.5573322	-0.2750032	-1.545437	275	FFAR4 GPR17 ACP5 IL17RB FOXF1 TEK EDNRB PPARG WFDC1 IL1B FABP4 CDH5 LPL CALCRL MYD88 CASP12 IL1RL1 IL23A DNASE1L3 PDE2A APOD ANXA1 MIR146A PLA2G7 ADA CLEC7A FOXP1 GATA3 SIRPA RB1 GRN CASP5 SLC7A2 IL10 BIRC2 MEFV CASP1 BST1 KLF4 CEBPA SOCS5 CCL3 NFKB1 NR1D2 PTPRC TLR4 PTGER3 FCER1G PER1 PTGIS HCK IL17D IL6 SOCS3 APPL1 PSMA1 ETS1 PTGER4 CCR7 OSM SUCNR1 CST7 BCL6B TREX1 PIK3AP1 SMPDL3B CD6 FPR2 NLRP6	down	**
GO_INFLAMMATORY_RESPONSE	0.0000002	0.0000239	0.6901325	-0.2583779	-1.543202	562	FFAR4 CXCL3 GPR17 NLRC4 ACP5 IL17RB IL1A FOXF1 HMOX1 TEK OLR1 EDNRB PPARG WFDC1 IL1B FABP4 LIPA BMP2 CDH5 LPL CD44 LY86 CCL3L1 CCRL2 CALCRL MYD88 TBXA2R C5AR1 CASP12 IL1RL1 IL1RN SLC11A1 NFATC3 IL23A HSPG2 ACER3 DNASE1L3 PDE2A APOD CD36 ANXA1 MIR146A PLA2G7 ADA CLEC7A TNIP3 FOXP1 PTX3 GATA3 JAM3 SIRPA RB1 IL18R1 NFE2L2 GRN CASP5 SLC7A2 IL10 MAP2K3 PTGIR CCL22 BIRC2 MEFV CASP1 BST1 PTAFR KLF4 AOC3 THBS1 CEBPA SOCS5 LY96 CCL3 NFKB1 NR1D2 PTPRC CXCL2 IRAK2 SELP AXL CCL4 TLR4 PTGER3 XCL2 FCER1G PER1 CYP26B1 PTGIS HCK NRROS PRCP RBPJ IL17D CNTF IL6 PSEN1 SOCS3 SNAP23 APPL1 C1QA JUN PSMA1 NOTCH1 ETS1 HRH1 TYROBP TREM1 IFNGR1 PTGER4 CCR7 OSM PTGER2 REL SUCNR1 CXCL5 CST7 PXK NDST1 FOS SIGLEC1 BCL6B TREX1 PIK3AP1 SMPDL3B CCR4 CHIA TGFB1 CD6 FPR2 NLRP6 CD81 ORM2 CCR1 PLAA CCL20 SYT11 UNC13D CCR6 ICAM1 IL18 IL18RAP LAT CXCR4 RIPK2 NLRP3 HAVCR2 EPHA2 PLGRKT TLR10 NFKBIA ADORA2A KIT CTSC SCUBE1 AIM2 P2RX1 RORA THEMIS2 ITCH LDLR ANO6 LYZ SPHK1 MS4A2 CYBA SERPINE1 C5AR2 CNR2 C5 CLOCK ITGAL TREM2 ZYX S100A8 FPR1 NDFIP1 TBC1D23 NFAM1 PTGS1 PIK3CG SIGLEC10 BDKRB2 FPR3	down	***
GO_EXOCYTOSIS	0.0000000	0.0000005	0.7749390	-0.2535201	-1.542197	727	SIRPB1 RAB11FIP1 SLPI FOXF1 HMOX1 FCN1 OLR1 PECAM1 HVCN1 CD55 GATA2 MNDA CLEC3B LTA4H CAT RAB44 P2RY1 CLEC12A RAB3C PTPRB OSCAR MMRN1 CD44 STXBP6 CTSW PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 STX11 MANBA VAPA CD9 FUCA1 GAS6 LAMP1 CBL SLC11A1 LILRB3 FGR RHOA CD36 ANXA1 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB RAPGEF4 ASAH1 RAP1A GM2A RAB33B ANXA5 ANPEP PRSS12 PTX3 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 SRGN PDGFA RAB14 CD58 CST3 FABP5 CFD RAB12 EXOC3L2 EXOC3L1 SDCBP LIN7C BST1 PTAFR PLAUR REST ROCK1 GAA OSTF1 THBS1 STX3 ATP6V1D FAM49B ABCC4 CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL SELP HPSE ARHGAP9 CD53 FCER1G PIK3C2A PLEK GCA GNAI2 DEGS1 ANXA3 BACE1 CMTM6 CPLX1 LIN7A VWF ACTR2 TGFB2 GLB1 HEXB HCK HGSNAT RAB6A NCKAP1L PRCP ARHGAP17 VAMP3 CTSS PSEN1 PHACTR2 NKD2 SNAP23 RAB8B PDCD6IP CYB5R1 VAT1 NOTCH1 RAB31 HK3 CTSZ ADRA1A RAC2 TYROBP HSPA1B ATP11A RHOG ENPP4 GLIPR1 GMFG RAB8A SERPINB6 UNC13B CAP1 RALB TAGLN2 BLOC1S6 CALM1 PSMD12 PRKCG ALDH3B1 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 TGFB1 TMX3 AP1G1 DOK3 MILR1 SERPINB1 FPR2 CDC37L1 TSPAN14 MIA3 DYNC1LI1 ATP6V0C GPR84 APLP2 LGALS3 EXOC1 ORM2 BRI3 CCR1 CLASP2 ACTN2 PLEKHO2 ADAM10 IST1 SYT11 COMMD9 UNC13D	down	***
GO_REGULATION_OF_SEROTONIN_SECRETION	0.0016604	0.0313933	0.4550599	-0.9838149	-1.539121	2	SLC6A4	down	*
GO_CYTOKINE_PRODUCTION	0.0000002	0.0000202	0.6901325	-0.2547178	-1.538997	608	POLR3H FFAR4 NLRC4 EREG ACP5 IL17RB IL1A HMOX1 FCN1 SCIMP SIGLEC16 CCM2L CD55 SPN IL1B FABP4 MNDA LIPA LRRFIP1 LPL JPH4 MYD88 C5AR1 IL1RL1 IL1RN GAS6 SLC11A1 NFATC3 RFTN1 IL23A FGR HEG1 APOD CD36 ANXA1 MIR146A TNFRSF8 ATP2B1 CARD16 CD33 ADAM17 CLEC7A HSPB1 RNF125 LITAF FOXP1 GATA3 SIRPA RGCC IL18R1 TRAF6 SPTBN1 CRTAM WNT3A SRGN ARHGEF2 PDE4D CD58 NODAL IL10 MAP2K3 ROCK2 ARRB1 BIRC2 MEFV CASP1 PTAFR KLF4 THBS1 CLECL1 SOCS5 LY96 FAM49B CCL3 NFKB1 CADM1 PTPRC AXL HPSE TLR4 MIR24-2 SFTPD FCER1G PER1 SMAD7 INHBA CLEC9A TGFB2 NRROS NCKAP1L RBPJ IL17D CD80 ELF1 IL6 CD160 PSEN1 APPL1 SEC14L1 NOTCH1 CARD8 TYROBP HSPA1B IFNGR1 PTGER4 CCR7 PIK3R1 CD83 IRF8 CREB1 OSM MALT1 REL SUCNR1 TBX21 TIGIT CD34 PLCG2 PELI1 KLF2 AZI2 MBP TREX1 CD74 WNT11 IRF5 CHIA TGFB1 AKIRIN2 SERPINB1 CD6 LRRC32 CD86 CD81 KLRC4-KLRK1 ORM2 NPTN GATA6 GPR18 LTBP1 PDE4B MR1 TSPO SYT11 IL18 IL18RAP ARRB2 RIPK2 NLRP3 HAVCR2 EPHA2 CREBBP TLR10 KIT KLRK1 LTBP3 MCOLN2 AIM2 FGFR1 RORA ITCH IQGAP1 PUM1 ATF4 SMAD4 BANK1 FLT4 SPHK1 CSF2 CYBA KAT5 EGR1 SERPINE1 C5AR2 ATF2 CX3CR1 CLEC4E C5 TREM2 S100A8 ZFP36 NDFIP1 TBC1D23 NFAM1 PIK3CG MUL1 POLR2L WNT5A SSC5D BCL10 AKAP12 HMGB1 DDX21 NMI EP300 CD3E IRF1	down	***
GO_REGULATION_OF_MITOTIC_CELL_CYCLE	0.0000052	0.0003685	0.6105269	0.3090862	1.536849	548	HMGA2 MCIDAS TRIP13 CEP72 BRINP1 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF STOX1 NDC80 BRCA1 TTK CDK4 SMPD3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN NABP2 CEP70 PLK1 AURKB PTTG1 ESPL1 CDC6 TPX2 TFDP2 PRKCA CDC25A ORC1 DTL ZFYVE19 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 CASP2 HMMR BTRC SMARCD3 DLG1 NLE1 FOXA1 MKI67 CUL9 CUL7 KNTC1 BUB1 LGMN TOP2A AURKA EME1 ODF2 SFI1 TPR MAD1L1 CLSPN TTLL12 CDCA5 PRKDC FSD1 TOM1L1 KIF11 GPSM2 CDC25C SOX4 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 PKMYT1 BLM PML CNOT3 ERCC2 PSRC1 PTPN3 INCENP CKS1B AFAP1L2 CDKN2C NUSAP1 ANAPC5 CTDSP2 CDK1 CEP97 CENPJ RFWD3 E2F1 PSMB5 TMEM8B ANAPC7 EZH2 CNOT11 EGF MTBP PSMC4 MAD2L2 KLHL22 FGFR1OP CEP63 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 CNOT2 PSMA5 NINL TACC3 RAD9A PSME2 MTA3 FZR1 KIF20B ASNS ANAPC1 CDK13 PSMD2 ATAD5 CDC7 SH2B1 CKAP5 PSMB3 CDC20 GBF1 BCL2L1 CHMP4C WNT10B CDK5RAP2	up	***
GO_MESENCHYME_DEVELOPMENT	0.0005778	0.0151311	0.4772708	-0.2806065	-1.535792	223	SEMA6B SEMA3G SEMA6A TMEM100 ACVRL1 FOXF1 EDNRB GLIPR2 IL1B WNT4 BMP2 ENG FOLR1 CORO1C CITED2 BMPR2 FGF10 TGFBR3 TGFBR2 ZEB2 SEMA6D TBX2 SEMA3B FOXA2 ADIPOR1 RGCC SFRP1 WNT3A TCF7L2 FOXC2 NODAL TAPT1 SNAI1 SDCBP DAB2 SMAD7 TBX5 ACTG2 PEF1 DCHS1 HES1 TGFB2 RBPJ PPP2CA IL6 NOTCH1 DDX17 DDX5 KBTBD8 POGLUT1 PKD2 WNT11 EPHA3 TGFB1 TGFB1I1 CLASP2 SMAD2 LDLRAD4 EPB41L5 OSR1 SEMA4A RTN4 TIAM1 S100A4 RET EDN1 PTEN FGFR1 NRP2 NRG1 ZFPM2 SMAD4	down	*
GO_GAMETE_GENERATION	0.0000457	0.0021039	0.5573322	0.3127775	1.535567	443	TSPAN8 TRIP13 TP63 SPATA24 SPATA25 MYCBPAP FOXA3 RUVBL1 PMFBP1 CCNB1 WFDC2 DPY19L2P1 GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 SPINK1 CIB1 TDRKH MCM8 SRPK1 RSPH1 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A AURKA REC8 ODF2 SYCP2 POC1A DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 OAZ3 CGB7 HSF2BP BRIP1 SPAG8 PTGDR2 CCDC136 MEA1 ASF1B LRGUK MERTK PICK1 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 MTOR CTSV MNS1 ADAM28 IQCG MORN2 PCSK4 GAS2 TSSK3 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 TYRO3 NR6A1 KDM3A PTN MEI1 ROPN1B BCL2L1 CATSPER2 BAD DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 GGT5 ETV6 PHC2 PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2	up	**
GO_ORGANELLE_ASSEMBLY	0.0000021	0.0001798	0.6272567	0.3048070	1.534223	679	CCNO PKHD1 MCIDAS ONECUT2 ONECUT1 CEP72 SPICE1 MDM1 CEP89 RPGRIP1L CHEK2 NEK2 CENPF AVIL NUDCD3 RAB3IP MKS1 CCDC113 BRCA1 SIX4 STK36 RACGAP1 IFT122 SPAG17 ANLN SNF8 ASPM STIL MSTO1 TTC26 CEP70 PLK1 IFT27 AURKB CENPA TPX2 MYBL2 GRB7 PLS1 PIP4K2C KIF27 DCTN2 WDR90 DNAI1 HAUS5 CEP250 WDR62 RSPH1 ARMC4 TNNT2 NLE1 KIF23 BBS1 SPAG16 BICD1 FOXJ1 KIF3B CCDC13 FBF1 MAP10 AURKA ODF2 SFI1 IFT43 TPR CENPW POC1A HYDIN MAP1LC3C WIPI2 TEKT2 ERAL1 CCDC114 DCDC2 FHOD3 KIF11 GPSM2 WDR60 NME5 DNAH8 IFT172 NEB GAS8 KIF3C CBY1 DNAAF3 MRPS11 RABEP2 CCDC136 C2CD3 CCDC40 CCDC78 HPS4 DRC1 LRGUK LRRC6 IQCB1 CDK1 CROCC CEP97 CENPJ CENPH BIRC5 KIAA0753 STX18 VANGL2 VPS28 MRPS2 TCTN2 KIF2A RUFY4 SSX2IP DYNLL2 SPAG5 POC1B TRAPPC12 DNAH5 PRKAA2 NOP2 TMEM231 FGFR1OP IFT52 KPNB1 EIF6 ULK1 CEP63 BBS5 CEP192 NPHP1 TUBG1 DNAH7 CNOT2 NINL MNS1 CCDC151 MRPL11 IQCG TRIM37 TMEM237 ATG9B VIL1 SPAG1 TEKT3 SMIM22 KRT19 TRAF3IP1 DNAJB13 CENPK PROX1 SASS6 CKAP5 VPS25 CDC20 IQUB WDR34 NPRL3 AAAS TTLL3 TCTN1 NRXN2 CHMP4C CDK5RAP2 KRT8 ODF2L CENPT DNAI2 WDR35 ANKRD1 HAUS6 DYNC2H1 FAM161A TBC1D30 RCC1 WDR45B HAUS4 LSM4 MYH3 RSPH4A SH3PXD2B TCHP UNC119B CEP152 RAB34 NUP62 TMEM17 B9D1 ALMS1 DBNL TUBGCP4 ICK CEP164 CLUAP1 DNAH1 CHMP1A MARK4 NLGN2 CHMP2A CELSR2 TBC1D32 TTC39C ATG2A VDAC3 CENPE MAP1LC3A UBXN10 LRSAM1 CELSR3 GOLGA2 HGS SYNE2 TTC30B CAPN9 MRPL20 ZMYND10 MAP9 RRS1 WIPI1 NLGN1 CLASP1 KIF24 BRIX1 TRAPPC6A POGZ KIAA0586 TPM1 CEP290 CHMP6 RPL23A ARMC2 MRTO4 DNAAF1 DRG1 DYNC1H1 MAK TEKT1 ABLIM3 WRAP73 WDR63 ARHGEF5 PLK4	up	***
GO_CELL_CHEMOTAXIS	0.0002352	0.0076900	0.5188481	-0.2782617	-1.533604	234	CXCL3 IL1A SWAP70 CXCL16 EDNRB IL1B CCL3L1 CCRL2 C5AR1 S1PR1 IL1RN GAS6 IL23A ANXA1 PLA2G7 HBEGF SBDS ADAM17 HSPB1 NR4A1 JAM3 CRK PDE4D IL10 CCL22 PTPRO BST1 THBS1 CCL3 CXCL2 CCL4 SFTPD XCL2 FCER1G DUSP1 OXSR1 AKIRIN1 TGFB2 NCKAP1L FLT1 IL6 NOTCH1 HRH1 RAC2 RHOG CCR7 DAPK2 ACKR3 GPR183 CXCL5 CD74 BIN2 CCR4 VAV3 ITGA9 FPR2 LGALS3 KLRC4-KLRK1 CCR1 GPR18 ADAM10 PDE4B CCL20 CCR6 FGF2 ARRB2 TIAM1 CXCR4 CCR9 EPHA2 PARVA KIT EDN1 KLRK1 MTUS1 LYST FGFR1 DOCK4 IL16 ANO6 GREM1 SERPINE1 C5AR2 CNR2 CX3CR1 C5	down	**
GO_TEMPERATURE_HOMEOSTASIS	0.0024466	0.0403154	0.4317077	-0.2956580	-1.531019	145	FFAR4 EPAS1 IL1A NOVA2 EDNRB IL1B FABP4 TRPV2 CAV1 CD36 ADAM17 ADIPOR1 ABHD6 ADRB1 RB1 ADRB2 IL18R1 FOXC2 FABP5 PRDM16 FOXO1 ZNF423 ARNTL NPR3 PER2 TLR4 PTGER3 ADIPOR2	down	*
GO_POLYMERIC_CYTOSKELETAL_FIBER	0.0000156	0.0009064	0.5756103	0.3097097	1.529855	509	KIF1A SAA1 KIF12 KLC3 KIF20A MDM1 KRT5 PKP2 DNAH2 RPGRIP1L NEK2 KIF18B PKP1 TUBB2B RACGAP1 GTSE1 KIF14 SPAG17 ASPM PLK1 KRT16 AURKB TPX2 DNAH3 PRC1 PLS1 DYNC1I1 CCT6A KIF27 CDK5RAP3 KRT15 DNAH14 CCT2 DCTN2 NME1 MICALL2 DNAI1 HAUS5 RSPH1 TTLL4 DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 KNTC1 KIF3B FBF1 MAP10 CCT5 GPER1 AURKA ODF2 FLG KIF2C CD2AP MAP1LC3C TEKT2 FSD1 HOOK1 DCDC2 KIF11 LMNB1 DNAH8 GAS8 KIF3C DNAH11 TRPV4 MYO1A PSRC1 INCENP KNSTRN NUSAP1 PAK1 KRT18 CDK1 DNAH6 KIF5A CENPJ BIRC5 CCT3 TTLL9 JAKMIP1 SCTR KIF19 SPAG6 KIF2A NARF KIF7 DYNLL2 SPAG5 DNAH5 KLHL22 EIF6 UPP2 TUBG1 DNAH7 DNAJA3 NINL LMNB2 MNS1 TUBB2A TUBA3D KIF22 DNM1 DBN1 TUBA8 KIF21A GAS2 HID1 MAP6D1 KIF20B SMTNL1 KRT19 TWF1 POLB CCT7 KLC2 KLC4 CKAP5 TUBG2 TTLL3 CDK5RAP2 KRT8 DYNC1LI2 KIF21B EML6 TBCA CKAP2 DNAI2 KPTN HAUS6 DYNC2H1 FAM161A RAB3D KATNB1 SKAP1 TTLL6 HAUS4 NEFH TCHP KRTAP5-9 MICAL3 APC2 DBNL NAV1 TUBGCP4 SYBU ACKR2 CCDC181 DNAH1 HOOK2 TUBA4B TPGS2 CDK5 CTTN TBCB BCAS3 CAMSAP3 CENPE MAP1LC3A SRPRB GOLGA2 ESPN TTC30B DCDC1 PNN KRT80 TUBA1C KRT17 MAP9 BFSP2 DNM1L TTLL5 CLASP1 KIF24 MAP2K2 CORO1B ROR2 TPM1 DNAL4 SHROOM1 VPS18 DYNC1H1 TEKT1 BAG2 GSK3A RUSC1 FAM110C PCNT TUBGCP2 KIFAP3 LZTS2 PARP4 RCC2 NCKIPSD TPPP3 NDRG1 TMEM214 KIF6 WIPF3 RAC3 KEAP1 TPPP LRPPRC FMN1 REEP4 DYNLT1 CALM3 DNAH9 DPYSL3 DSP TUBGCP5 DLGAP2 KIF3A PAWR	up	***
GO_RESPONSE_TO_BACTERIUM	0.0000023	0.0001864	0.6272567	-0.2622487	-1.527943	447	SMAD6 SIGLEC11 CXCL3 NLRC4 SLPI ACP5 KMO IL1A SASH1 EDNRB SCIMP SIGLEC16 CD55 SPN PGC IL1B FABP4 THBD BMP2 LPL LY86 CAV1 BAIAP2 MYD88 CHIT1 TBXA2R C5AR1 FGF10 IL1RN SLC11A1 PPM1D TRIB1 IL23A FGR CASP9 RHOA CD36 MIR146A CARD16 ADAM17 TNIP3 LITAF FOXP1 MS4A1 SERPINB9 SIRPA TRAF6 GRN PDE4D RAB14 GPM6A IL10 PTGIR MPEG1 CASP1 PTAFR ADAMTS9 LY96 CCL3 NFKB1 CXCL2 IRAK2 VIM SELP AXL TLR4 SFTPD FCER1G C4BPB IL24 ANXA3 GNRH1 HCK SNX3 RBPJ CD80 IL6 CD160 JUN NOTCH1 CARD8 JUNB PTGER4 CCR7 IRF8 PRKCE PTGER2 MALT1 UNC13B CXCL5 IGKV3-20 PLCG2 FOS PELI1 MAPK8 CCR4 IRF5 TGFB1 AKIRIN2 CD1D CD6 FPR2 NLRP6 IFNAR1 CD86 PLSCR4 KLRC4-KLRK1 IGHV3-23 PLAA PDE4B MR1 TSPO CCL20 SYT11 JUND ICAM1 IL18 VGF TFPI SCN7A TAB2 RIPK2 NLRP3 HAVCR2 MT1M EPHA2	down	***
GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	0.0001524	0.0053058	0.5188481	-0.2726382	-1.527481	271	SMAD6 TMEM100 ACVRL1 SOSTDC1 SFRP4 GREM2 BMPER BMP2 CDH5 ENG FOLR1 CAV1 CITED2 BMPR2 RBM14 FGF10 TGFBR3 CBL TGFBR2 RHOA TMPRSS6 LTBP4 ADAM17 NLK CAV2 SFRP1 SPTBN1 ZFYVE16 ZEB1 UBE2D3 NODAL PRDM16 SDCBP NPNT ZNF423 DAB2 THBS1 CLDN5 VIM SMAD7 INHBA VEPH1 HES1 HTRA4 MIR17HG TGFB2 NRROS RBPJ ADAMTSL2 APPL1 MAGI2 JUN NOTCH1 LTBP2 BMP3 FERMT2 SKIL DDX5 CREB1 FSTL3 FOS UBB TGFB1 PARD6A ZFYVE9 TGFB1I1 LRRC32 MYOCD TOB1 LTBP1 SMAD2 LDLRAD4 FKBP1A ARRB2 CDKN1C DACT2 UBE2D1 CREBBP ING2 ETV2 SKI LTBP3 SMAD4 SKOR1 ARHGEF18 ACVR1C EGR1 GREM1 DKK3 LNPEP ZYX CD109 NOG SNW1 CTDSPL2	down	**
GO_TISSUE_REMODELING	0.0019158	0.0343021	0.4550599	-0.2943722	-1.526998	143	EPAS1 ACP5 ACVRL1 IL1A ACE SNX10 DCSTAMP LIPA CAV1 BMPR2 S1PR1 FGF10 IL23A ANXA1 PPP3CA ADRB2 TRAF6 SFRP1 TFRC FOXC2 CST3 ROCK2 ROCK1 TPP1 TMBIM1 AXL UBASH3B PTH1R PDK4 RBPJ IL6 MITF RAC2	down	*
GO_PHAGOCYTOSIS	0.0002708	0.0084697	0.4984931	-0.2724026	-1.525533	270	SIRPB1 CD300LF FCN1 PECAM1 PPARG FCN3 GATA2 IL1B FYN CORO1C BAIAP2 MYD88 ELMO1 CDC42 MARCO NCF2 GAS6 SLC11A1 PEAR1 FGR CD36 ANXA1 IGKV2-28 RAP1A CLEC7A PTX3 SIRPA CD93 CRK RAB14 MSR1 THBS1 PTPRC AXL TLR4 CD302 ACTR3 SFTPD FCER1G LYAR C4BPB ANXA3 ACTR2 HCK NCKAP1L SNX3 IGLV2-11 MYO1C WASF2 IL2RB APPL1 RAB31 RAC2 TYROBP RHOG RAPGEF1 PIK3R1 IRF8 PRKCE GRB2 IGKV3-20 PLCG2 ATG3 PRKCG TREX1 BIN2 VAV3 JMJD6 FPR2 IGHV3-23 IGKV1D-39 SYT11 UNC13D ARPC2 XKR8 RAB5A HSP90AA1 ACTB ICAM3 ADORA2A CD3G ARPC5 PTEN ANXA11 LDLR ANO6 SPHK1 ABI1 CYBA IGKV2-30 MAPK1 ITGAL ITGB1 TREM2	down	**
GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT	0.0002318	0.0076261	0.5188481	-0.2743943	-1.524887	241	SLC6A4 TNR DAB1 SEMA6B SEMA3G SEMA6A EDNRB DENND5A IL1B RAPGEF2 FIG4 ARHGEF15 DDX6 CTDSP1 RHOA SEMA6D MIR146A ASAP1 SEMA3B PAQR3 EIF4E PPP3CA WNT3A ARHGEF2 ZNF365 LRP4 PTPRO TRIM46 DAAM2 REST ID3 VIM ID2 PAFAH1B1 RUFY3 HES1 KREMEN1 GNRH1 SRGAP2C KANK1 MYLIP ID4 CNTF IL6 PSEN1 NOTCH1 CTSZ CNTN4 BAG5 IFRD1 LSM1 RTN4R PRKACA TRAK2	down	**
GO_MYELOID_LEUKOCYTE_DIFFERENTIATION	0.0005800	0.0151477	0.4772708	-0.2894610	-1.524500	176	CD101 TAL1 PPARG GATA2 SNX10 DCSTAMP OSCAR PDE1B CDC42 TGFBR2 TRIB1 LILRB3 IL23A KLF10 FOXP1 GATA3 RB1 TRAF6 SFRP1 SPI1 TFRC EVI2B CEBPA CCL3 ID2 TLR4 FCER1G INHBA UBASH3B PAFAH1B1 NRROS RBPJ PSEN1 JUN MITF CUL4A TYROBP JUNB OSTM1 CCR7 SP3 PIK3R1 GPR183 CREB1 SIGLEC15 FSTL3 RASSF2 FOS CD74 TGFB1 CBFA2T3 CD81 CCR1	down	*
GO_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT	0.0020373	0.0354635	0.4317077	-0.3020090	-1.524360	128	TNR DAB1 SEMA6B SEMA3G SEMA6A DENND5A RAPGEF2 RHOA SEMA6D ASAP1 SEMA3B PAQR3 PPP3CA WNT3A ZNF365 LRP4 PTPRO TRIM46 VIM PAFAH1B1 RUFY3 KREMEN1 SRGAP2C KANK1 MYLIP PSEN1 CTSZ BAG5 IFRD1 RTN4R TRAK2	down	*
GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	0.0002848	0.0088005	0.4984931	-0.2878810	-1.523644	189	SMAD6 ACVRL1 SOSTDC1 SFRP4 GREM2 BMPER BMP2 CDH5 ENG FOLR1 CAV1 CITED2 BMPR2 FGF10 TGFBR3 TGFBR2 TMPRSS6 LTBP4 ADAM17 CAV2 SFRP1 SPTBN1 ZEB1 NODAL PRDM16 SDCBP NPNT ZNF423 DAB2 THBS1 SMAD7 INHBA VEPH1 HES1 HTRA4 MIR17HG TGFB2 NRROS RBPJ ADAMTSL2 MAGI2 NOTCH1 BMP3 SKIL FSTL3 UBB TGFB1 TGFB1I1 MYOCD TOB1 LTBP1 SMAD2 LDLRAD4 FKBP1A CDKN1C DACT2 CREBBP ING2 SKI SMAD4 SKOR1 GREM1 DKK3 CD109 NOG SNW1 CTDSPL2 WNT5A EP300 RNF111 WWTR1 GDF7	down	**
GO_FAT_CELL_DIFFERENTIATION	0.0004647	0.0128679	0.4984931	-0.2895438	-1.522761	180	FFAR4 SMAD6 OSBPL11 PPARG GATA2 LRRC8C FABP4 BMP2 INSIG1 LPL EGR2 FGF10 MIR27B ADRB1 GATA3 NR4A1 ADRB2 SFRP1 WNT3A HNRNPU TCF7L2 PRDM16 FOXO1 KLF4 RUNX1T1 ZADH2 ARNTL CEBPA GRK5 PER2 ID2 ARL4A HES1 MEDAG PIAS1 ID4 IL6 EBF2 CCDC3	down	*
GO_CIRCULATORY_SYSTEM_PROCESS	0.0000090	0.0005628	0.5933255	-0.2618124	-1.522259	409	SLC6A4 EPAS1 HSPB7 RAMP3 ACVRL1 HMOX1 TEK OLR1 ACE EDNRB PPARG P2RY1 EMP2 RAMP2 CDH5 FYN CAV1 NEDD4L ADRA1D BMPR2 CYB5R3 TBXA2R HMGCR FXYD2 MEF2A CDC42 GAS6 CYP4A11 SCN5A HEG1 RHOA PDE2A TBX2 ATP2B1 PTPRM HBEGF ADA CACNA2D2 KCNK3 ADRB1 DES ADRB2 CES1 TCAP PDE4D TMEM38B FOXC2 FLI1 MAP2K3 ROCK2 TNNC1 KCNMA1 PTPRO TACR2 PTAFR ROCK1 GAA NPR3 PER2 P2RY2 KCNMB1 ID2 XCL2 PIK3C2A SMAD7 ZMPSTE24 RAP1GDS1 FXYD7 GNAI2 CALM2 TGFB2 PRCP KCNA5 SLC8A1 SCN4B SGK1 HRH1 CTSZ ADRA1A PDE5A RCAN1 GSTO1 PTGER2 NPR1 PRKACA SUCNR1 CELF2 CD34 GPR37L1 CALM1 TREX1 SLC4A5 MME CPA3 FXYD6 TGFB1	down	***
GO_CHROMOSOME	0.0000000	0.0000014	0.7614608	0.2960946	1.522179	1222	HMGA2 SIM2 MNX1 PKHD1 TRIP13 ONECUT2 ONECUT1 HNF1A TP63 DDX11 FOXM1 HELLS FOXA3 HJURP STAG3L2 RUVBL1 CDC45 PARPBP MCM10 PAX9 ASCL5 TFAP2A CHEK2 BUB1B NUP107 HOXD8 NEK2 TRNP1 CCNB1 SOX2 CENPF TIMELESS POLQ HOXB6 ZFHX4 CPSF6 NPAS1 TSHZ2 THOC3 NDC80 PRIM2 PIF1 BRCA1 SPDEF CREB3L4 FOXD4 SIX4 FANK1 ZFHX2 TTK GINS1 CDCA2 CDK4 E2F8 FOXE1 L3MBTL1 NPAS2 POLE NABP2 IRX6 PLK1 NUF2 CDCA8 AURKB CENPA SIX1 EBF3 WDR70 TBX19 SOX9 E2F3 TFDP2 FIGNL1 RBBP8 UHRF1 MCM4 HOXB7 MCM2 GRHL3 SP5 MYBL2 XRCC2 ORC1 DTL DYNC1I1 HNF4G MCM8 ASXL3 MIS18A GINS4 RCCD1 NCAPD2 ZWINT CDT1 DCTN2 SPDL1 TOP3B RSPH1 RUVBL2 SDR16C5 SMARCD3 SMARCC1 SOX30 STAG3 CHAF1A FOXA1 MKI67 BOD1 TP53BP1 FOXJ1 KNTC1 RHNO1 BUB1 MSX2 AUNIP TOP2A CENPL AURKA EME1 CBX3 REC8 POLA2 SYCP2 ATR POLD2 TPR IRF3 SMARCAL1 KIF2C MCM7 MAD1L1 ZNF174 E2F2 MSX1 CENPW MMS22L CDCA5 PRKDC TRRAP WDHD1 CSRNP3 HOXC6 HELB SETDB1 FANCD2 MCM3 CHAF1B HORMAD1 SOX4 BRD9 EME2 MORC2 ZNHIT1 TOPBP1 CHEK1 ORC6 ACTL6A MAD2L1 NFYA SOX11 FBL CENPO CSRNP2 RAD51AP1 XRCC1 THAP10 HES6 SPC24 DSCC1 MGA EHF RAD18 HSF4 REPIN1 BLM GRHL2 PML HOXB5 TADA2A MEOX1 TFCP2 RECQL5 PARP1 PES1 INCENP KNSTRN NCAPG2 TERC NUSAP1 ETV7 CBX5 ASF1B PAK1 CDK1 CDK12 POLE2 RFWD3 CENPH BIRC5 ARPC1A PHF12 ZMIZ2 E2F1 TBX15 NCAPG PRRX2 STAT2 DNA2 POU5F1B FEN1 EZH2 SPAG5 THAP8 TRAPPC12 OARD1 TTI1 MTBP CBX1 MAD2L2 RECQL4 CENPP ARNT2 TEP1 IRF6 RANGAP1 TBX1 DNMT1 PELP1 TELO2 INTS7 ZGPAT OVOL3 FOXK1 TRIM24 TUBG1 DCLRE1C ALX4 SATB2 ADNP DVL3 MBD4 RAD9A KIF22 HIRA RAD51D HMGN3 MTA3 SALL4 SUDS3 SSRP1 C1orf131 CHTF18 NFATC4 CENPQ AKAP8L HDAC1 ESCO2 GINS2 ANP32E LIN37 LRWD1 OTX1 CHD5 KDM3B CDK13 POLD1 THRB NUP85 ESR1 ATAD5 ENC1 PARP9 SLX4 RAD50 NR6A1 CCDC137 ETV4 KDM3A ANKRD31 CENPK BAZ2A PROX1 KLHDC3 EP400 UBQLN4 SUPT16H STAG3L4 CENPV NFXL1 CKAP5 PPHLN1 BRD8 HNF1B CENPM TWIST1 HMGA1 RPA1 TFCP2L1 NOL6 MCM6 HOXA3 DNMT3A CHTF8 THOC5 WRNIP1 DYNC1LI2 ZNF446 CENPT MCM5 ZRANB3 TFAP4 NSD1 ADD3 HMCES NFE2 EXOSC5 ESRRA CREB3L2 ETV6 RCC1 PHC2 SMARCC2 GTPBP10 ESRRB ZNF580 MSH4 SUV39H2 LHX4 MCRS1 MSH2 SMARCA4 PRIM1 NFRKB GRHL1 BBX BANF1 MLXIP RTEL1 RFC5 STAT6 WDR4 INO80E RAD51 HLCS TNKS1BP1 BRMS1 ZWILCH SEC13 CHMP1A FOXD2 LLPH LBX2 PAXIP1 SOX12 CHMP2A CHD3 WDR76 HOXB2 MXD3 RBM19 SIRT6 SMC2 BCAS3 TONSL BCL6 XPC MAU2 CENPE TCF3 SRCAP SWI5 TP53 ZBTB32 NEIL1 LEMD2 APEX1 TAF4 NCAPD3 PWP1 RORC RAD1 SMARCB1 E2F7 RRS1 NAT10 MUC1 THAP3 HOXA6 CLASP1 ZFPM1 ASCL2 ACTR5 SS18L1	up	***
GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS	0.0006278	0.0159045	0.4772708	-0.2905857	-1.520061	175	LPIN2 PPARG CPEB2 IL1B PTPRE PID1 KL PCSK9 LPL INPP5K BAIAP2 VAMP2 ATP2B1 CAV2 ADIPOR1 NDEL1 ATP6V1H ATP6V1B2 FOXC2 RAB12 FOXO1 SRSF5 SORBS1 ATP6V1D PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 SLC25A33 PDK4 KANK1 MYO1C SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 RAB8A ATP6V0D1 RHOQ FOXO3 ATP6V1A IRS2 ATP6V0C	down	*
GO_MUSCLE_TISSUE_DEVELOPMENT	0.0001369	0.0049434	0.5188481	-0.2646100	-1.519188	306	RBP4 CCM2L TBX3 BMP2 SIK1 ENG EGR2 CAV1 GPCPD1 S1PR1 HMGCR PRKAR1A MEF2A CDC42 TGFBR3 TGFBR2 HEG1 RHOA KCNAB1 JPH2 TBX2 MYOZ1 LMNA CSRP1 BTG2 CAV2 HLX PPP3CA RB1 WNT3A HNRNPU TCAP FOXC2 TIPARP TNNC1 YBX3 ZFAND5 ARNTL ADAMTS9 NR1D2 ATF3 ID2 MIR24-2 SMAD7 ZMPSTE24 TBX5 VAMP5 CYP26B1 MYH11 MAFF MIR17HG AKIRIN1 TGFB2 LMOD3 MTPN SRF RBPJ SLC8A1 COPS2 NOTCH1 ADRA1A DDX17 FOXN2 IFRD1 DDX5 CREB1 HOMER1 NDUFV2 POGLUT1 FOS CACYBP PKD2 SAV1 TGFB1 MIR23A PIM1 MEIS1 MYOCD GATA6 ACTN2 RGS2 RXRA FGF2 PDLIM5 FKBP1A ARRB2 OSR1 EDN1 PTEN SKI FGFR1 MIR548C NRG1 ZFPM2 SMAD4 EGR1 GREM1 CDON CFL2 SVIL GJC1 MAPK1 MYH10 ITGB1 NOG EFNB2 CCNT2 CALR WNT5A PAX5 PLN	down	**
GO_CELL_DIVISION	0.0000377	0.0018180	0.5573322	0.3075384	1.518611	498	HMGA2 CCNO TP63 SPICE1 HELLS KIF20A CUZD1 RUVBL1 CHEK2 BUB1B NEK2 CCNB1 CENPF TIMELESS STOX1 KIF18B NDC80 CDCA2 CDK4 RACGAP1 E2F8 KIF14 ANLN ASPM PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 RBBP8 CDC25A PRC1 NOX5 CCNF CIB1 LIG3 MIS18A ZFYVE19 NCAPD2 ZWINT CDT1 SPDL1 LMLN HAUS5 KIF23 CEP55 BOD1 CUL7 KNTC1 KIF3B BUB1 TOP2A MAP10 AURKA THBS4 SYCP2 TPR KIF2C MAD1L1 CD2AP CENPW CXCR5 CDCA5 FSD1 NSUN2 KIF11 GPSM2 CDC25C MDK LIG1 ORC6 MAD2L1 SPC24 BRIP1 BLM ERCC2 PARD3 RECQL5 PSRC1 INCENP KNSTRN CKS1B NCAPG2 NUSAP1 ANAPC5 CDK1 CENPJ BIRC5 DIS3L2 NCAPG VANGL2 KIF2A ANAPC7 SPAG5 RAB11FIP4 SAPCD2 MAD2L2 KLHL22 GIPC1 MYO19 CEP63 CCNE1 RHOC CDC23 CDK3 TACC3 LLGL2 FZR1 PKP4 CLTA KIF20B ANAPC1 JTB CABLES2 CDC7 PTN CENPV CKAP5 CDC20 ROPN1B EFHC1 ALKBH4 BCL2L1 CHMP4C PELO STAMBP CENPT CKAP2 HAUS6 NEK4 KATNB1 RTKN RCC1 CCNG1 HAUS4 TXNL4A ANK3 ESRRB NUP62 MICAL3 CCNA2 ANAPC2 USP39 CEP164 ZWILCH CHMP1A MARK4 CHMP2A CDK5 SMC2 MAU2 CENPE E4F1 GOLGA2 CDC25B UBE2C DCDC1 NCAPD3 TUBA1C MAP9 E2F7 CLASP1 BRSK2	up	**
GO_SECRETORY_GRANULE	0.0000001	0.0000157	0.6901325	-0.2514414	-1.516859	636	SIRPB1 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 IL1B MNDA CLEC3B LTA4H SNX10 CAT RAB44 CLEC12A IZUMO1 PTPRB OSCAR MMRN1 CD44 CTSW CAV1 BAIAP2 CHIT1 CYB5R3 VAMP2 PAFAH1B2 TBXA2R C5AR1 YPEL5 CDC42 MANBA NCF2 VAPA CD9 FUCA1 GAS6 LAMP1 SLC11A1 LILRB3 FGR RHOA CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ASAH1 RAP1A GM2A ANPEP CAV2 PTX3 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 SRGN PDGFA RAB14 CD58 CST3 FABP5 CFD EXOC3L1 SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 THBS1 STX3 ATP6V1D MYRIP FAM49B ABCC4 SPAG9 CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL SELP HPSE ARC ARHGAP9 CD53 FCER1G GCA DEGS1 ANXA3 CMTM6 VWF ACTR2 TGFB2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP VAMP3 CTSS PSEN1 PHACTR2 EBAG9 SNAP23 CYB5R1 CAPN11 VAT1 NOTCH1 RAB31 SFTPB HK3 CTSZ TYROBP HSPA1B ATP11A RHOG STX7 SKIL ENPP4 GLIPR1 GMFG SERPINB6 CAP1 PRKACA TCP1 FSTL3 PSMD12 ALDH3B1 BIN2 CR1 MME CPA3 TIMP2 STXBP3 SIGLEC14 TGFB1 TMX3 DOK3 SFTPC SERPINB1 FPR2 CDC37L1 TSPAN14 DYNC1LI1 ATP6V0C SLIRP GPR84 APLP2 LGALS3 ORM2 BRI3 ACTN2 PLEKHO2 CSNK2A2 ADAM10 IST1 COMMD9 TCTEX1D4 UNC13D	down	***
GO_ADENYL_NUCLEOTIDE_BINDING	0.0000000	0.0000009	0.7614608	0.2944670	1.514971	1297	KIF1A ATP10B CPS1 KIF12 STYK1 TRIP13 HKDC1 ABCA13 DDX11 ENTPD2 ABCC2 HELLS EPHB3 KIF20A DDX12P RUVBL1 AK4 DNAH2 CHEK2 BUB1B SLFN13 MYO3B PPIP5K1 NEK2 XYLB FRK POLQ UBE2T PBK KIF18B TTF2 GUCY2C PIF1 NMNAT3 IP6K3 STK36 TTK CDK4 BRSK1 SLC27A2 KIF14 UBE2Z ABCA12 GMPS STK31 FLAD1 PLK1 AURKB ACAD9 ALDH18A1 PAK6 CDC6 WNK2 TRIB3 FIGNL1 MCM4 PRKCA MCM2 RAD54B DNAH3 PMS2 NWD1 XRCC2 ORC1 AACS CCT6A MCM8 PIP4K2C LIG3 MAP2K6 SGK2 SRPK1 KIF27 INSRR EPHB1 P2RX2 DNAH14 MPPED2 CCT2 AGK AK8 NME1 IKBKE AARS2 TTLL4 RUVBL2 MELK DYRK1B KIF23 MKI67 CUL9 SLFN5 HLTF KIF15 PCCB HS3ST5 MAP3K13 KIF3B BUB1 TOP2A CCT5 AURKA MYO10 ATR LARS2 SMARCAL1 KIF2C MCM7 COASY ABCC5 TTLL12 PRKDC RHOBTB3 HELB RAD54L PKM SBK1 EIF2AK1 PHKG2 KIF11 PASK MCM3 PEX6 MCCC2 TARS2 CHD6 EGFR DNAH8 LIG1 SARS2 RIPK4 MORC2 ABCB6 CHEK1 NEK11 ASS1 ACSF2 AHCY KIF3C EPHA10 PFKP ABCB9 HSP90AB2P MST1R KCNJ11 KHK AKT2 CNGB1 PKMYT1 DNAH11 BRIP1 DDR1 CAD BLM PPP5C ATAD3C ERCC2 TRPV4 HSPBP1 MYO1A TRIT1 RECQL5 DYRK2 DDX56 MARK1 TNIK IKBKB DCLK1 TTBK1 CBWD6 FASTK NSF DDX51 HARS2 PAK1 LRGUK CDK1 CDK12 DNAH6 EPHA1 KIF5A UCK2 MERTK STK32A CCT3 ATP2A1 TTLL9 TNK2 NAV2 DHX37 TRAP1 ABCC11 SYN3 MAP3K10 KIF19 DNA2 ACTR3C KIF2A DHX33 ACSBG2 KIF7 ITPKA KSR2 PDK1 NEK5 ACTR3B MYO5B AK7 ATAD3A DNAH5 PRKAA2 ABCA4 UCKL1 PSMC4 RTCB RECQL4 MAST1 ACVR1B STK11 TEP1 GAL3ST4 ULK1 DHX34 HSPA4L NMNAT2 MYO19 ACBD6 PARS2 MOV10 ANKK1 ILF2 CDK3 ATP7B DCAKD NEK10 NADK2 SPG7 DNAH7 DHX40 GALK2 TRMU MTOR GSS DNAJA3 ATP9A AARSD1 LONP1 TRIO KIF22 MAPK13 RAD51D EPHB2 ACBD4 UBE2Q1 TK1 DTYMK CHTF18 CNGA4 SCN8A KIF21A CSNK1G1 LMTK2 SLC22A5 HSP90B2P MAPK10 TSSK3 KIF20B NDUFA13 ASNS GK5 CHD5 CDK13 TTLL10 TWF1 ACSL6 SIL1 TYRO3 ATAD5 MAT1A ATP13A1 NADSYN1 CCT7 CDC7 IP6K2 YARS2 RAD50 ABCC10 TNK1 EP400 ACBD5 PFAS UBE2O ABCC9 ENTPD8 DGKA IARS2 ERBB3 POPDC2 TTLL3 ACLY ENTPD3 ABCC3 ABCA7 FANCM MCM6 MYO5C CKMT2 WRNIP1 DYNC1LI2 KIF21B CDC42BPG SRPK2 DHX8 MCM5 NMNAT1 ACOT11 ZRANB3 DDX23 DYNC2H1 NEK4 LANCL2 SCYL3 ADCK1 PIP5K1A MYH7B PFKFB4 LRRK1 TTLL6 IGHMBP2 MYH3 MAB21L1 MUSK ABCD4 PALM3 PRKD2 STK39 PI4KA STK35 DDX55 ATAD2 FARSA MYH13 ROS1 MSH4 PMS1 ATP6AP1 MSH2 MAP3K14 ME1 ADCY1 SMARCA4 ULK4 STK38 DDX54 ABCF3 RTEL1 CDC42BPA RFC5 CSNK1G2 NME4 PAK4 ICK ABCF2 ACSF3 NUBP2 DNAH1 HK2 BMS1 RAD51 HLCS FARSB STK25 MAP3K9 PFKM MARK4 SNRNP200 NME7 CHD3 CDK5 POMK ERBB2 NUBPL SMC2 PNKP ADCY6 CENPE EIF4G1 GNE SRCAP EARS2 MYO15A DDX52 HSPA7 GLYCTK MTHFD1 TP53 CBWD1 TSSK4 SEPHS1 PAICS TIMM44 EPHB4 UBE2C NPR2 RIPK3 ADCK2 OAS3 PI4KB NAT10 TK2 TTLL5 BRSK2 KIF24 MOK ALPK1 DDX41 MAP3K19 MAP2K2 ACSL5 NLRC5 ERCC3 PRKAG1 ROR2 SLFNL1	up	***
GO_REGULATION_OF_LYMPHOCYTE_ACTIVATION	0.0000198	0.0011195	0.5756103	-0.2606973	-1.513207	378	SIRPB1 CD55 SPN IL1B MNDA FYN CAV1 FGF10 PRKAR1A CDC42 GAS6 LAMP1 CD22 TGFBR2 IL23A FGR RHOA ANXA1 CLCF1 FBXO7 CD5 ADA CLEC7A MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 SFRP1 WNT3A ZEB1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 BST1 SLC46A2 CLECL1 SOCS5 MPL FAM49B CDKN1A PTPRC AXL ID2 TLR4 IGFBP2 SFTPD SMAD7 INHBA IL7R CYP26B1 HES1 MIR17HG GNRH1 NCKAP1L CD80 IL6 CD160 PDE5A RAC2 TYROBP CCR7 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 DOCK8 AP3B1 TBX21 ZNF683 TIGIT PELI1 TNFSF13 RUNX3 TREX1 CD74 CR1 TGFB1 VAV3 AP1G1 CD1D ZBTB1 CD6 LRRC32 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23	down	**
GO_CELLULAR_RESPONSE_TO_PEPTIDE_HORMONE_STIMULUS	0.0003947	0.0112050	0.4984931	-0.2708506	-1.512695	254	LPIN2 PPARG CPEB2 IL1B LHCGR ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A ATP2B1 ANXA5 CAV2 ADIPOR1 NR4A1 NFE2L2 NDEL1 CRK ATP6V1H ATP6V1B2 FOXC2 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 ROCK1 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 SLC25A33 PDK4 KANK1 MYO1C ADCY2 SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ FOXO3	down	*
GO_RESPONSE_TO_PEPTIDE_HORMONE	0.0000494	0.0022276	0.5573322	-0.2605470	-1.512269	341	EREG LPIN2 TEK EDNRB PPARG HHEX CPEB2 IL1B LHCGR CAT ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL EGR2 INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A TGFBR3 ANXA1 ATP2B1 BTG2 ANXA5 CAV2 ADIPOR1 NR4A1 NFE2L2 NDEL1 CRK EPM2AIP1 ATP6V1H ATP6V1B2 FOXC2 IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 ROCK1 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 GNRH1 BTG1 SLC25A33 PDK4 KANK1 MYO1C ADCY2 AREG SOCS3 APPL1 RAB8B STAT4 RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ CACYBP FOXO3 SRSF6 SORT1 STXBP3 SRSF4 GNAI1 ATP6V1A IRS2 ATP6V0C CRY1 ACTN2 KAT2B JUND ICAM1	down	**
GO_MOLECULAR_TRANSDUCER_ACTIVITY	0.0000001	0.0000077	0.7195128	-0.2461729	-1.510566	732	FFAR4 SMAD6 HCRTR1 CLEC1B GPR17 RAMP3 ACVRL1 IL17RB SOSTDC1 FCN1 TEK GPR15 EDNRB PPARG ROBO4 SPN TIE1 F2RL3 LHCGR P2RY1 LYVE1 GPR65 PTPRE RAMP2 THBD PTPRB ENG OSCAR FOLR1 CD44 HCAR2 CCRL2 INPP5K CALCRL CRY2 ADRA1D BMPR2 ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 MARCO NR3C1 TGFBR3 IL1RL1 TGFBR2 SCARF1 IGSF6 PEAR1 LILRB3 CD8A CD36 PKHD1L1 TNFRSF8 SSTR1 PTPRM LTBP4 CD5 CD33 LIFR CHRNE PLXNA2 CLEC7A FZD4 NMUR1 ANPEP PAQR3 ADIPOR1 ADRB1 NR4A1 PLXNA4 TMEM123 ADRB2 IL18R1 CD93 GPBAR1 GPR4 TAPT1 PTGIR EPOR PTPRO CLEC1A GPA33 TACR2 PTAFR PLAUR PAQR5 MPL NPR3 LY96 P2RY2 ITGAX NR1D2 PTPRC GPR85 AXL TLR4 CD302 RECK M6PR PTGER3 FCER1G RNF139 CD300C SMAD7 EVI2A ADIPOR2 KLRD1 CUL5 UNC5A GPR157 IL7R HLA-DQA1 CRIM1 PTH1R PROCR CD8B TRGC2 S1PR4 HCAR3 CD80 FLT1 GPR61 CD160 KLRB1 IL2RB TAS1R1 CD48 NOTCH1 HRH1 ADRA1A TREM1 IFNGR1 GPR141 PTGER4 CCR7 ACKR3 GPR183 PTGER2 NPR1 RTN4R GRIA1 SUCNR1 CD7 TNFRSF9 OGFRL1 TNFRSF10B GPRC5A ITGA11 TPRA1 GRIK1 FGFR4 GPR37L1 GPR3 CD74 KLRC2 CR1 CCR4 EPHA3 SORT1 NR2C1 JMJD6 GLRA3 FPR2 NLRP6 IFNAR1 CD86 CNTNAP1 GPR84 GLRA1 KLRC4-KLRK1 MRGPRF CCR1 CRY1 OR52B6 GPR18 LTBP1 MR1 TSPO IFNLR1 RXRA SMAD2 CCR6 NR2E3 ICAM1 INTS6 IL18RAP OPN3 HTR6 SEC63 CXCR4 EPHA4 CCR9 PTCH1 BCAM EPHA2 GRIN3A TLR10 RET ADORA2A KIT CD3G KLRK1 MMD GPR171 P2RX1 OR1K1 FGFR1 RORA NRP2 NR3C2 LPAR6 SMAD4 FLT4 TNFRSF10D FCRL1 SPHK1 KLRF1 ACVR1C CSF2RB C5AR2 GHR CTSH CDKN1B CNR2 NR4A2 CX3CR1 CLEC4E ITGAL ITGB1 TREM2 GPR153	down	***
GO_NEGATIVE_REGULATION_OF_GROWTH	0.0005293	0.0143041	0.4772708	-0.2783068	-1.509591	202	SLC6A4 TNR RBP4 SEMA6B SEMA3G SEMA6A ACVRL1 PPARG WFDC1 FBP1 DCSTAMP SOX17 BMPR2 TGFBR2 SEMA6D WWC2 MYOZ1 SEMA3B ADIPOR1 ADRB1 ADRB2 SFRP1 WNT3A PPT1 TRIM46 SOCS2 CDKN1A ST7L INHBA ADIPOR2 TBX5 MIR17HG CDKN2AIP TGFB2 BTG1 SERTAD2 PPP2CA PRDM11 NOTCH1 HSPA1B APBB2 IFRD1 NPR1 RTN4R WNT11 SAV1 TGFB1 OSGIN1 APBB1 MEIS1 RGS2 SEMA4A RTN4 PTCH1 MT1M ULK2 STK4 PTEN MT2A SMAD4 GREM1 CDKN1B ING1 DCUN1D3 OSGIN2 NOG MT1E MUL1 WNT5A	down	*
GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING	0.0019606	0.0347363	0.4317077	-0.2941842	-1.505734	140	EREG RAMP3 TEK ENG KL FYN BAG4 FGF10 GAS6 HBEGF GATA3 SPRY2 TCF7L2 TXN PDGFA THBS1 CCL3 EPGN AXL HPSE PINK1 PIK3R5 CD80 AREG RAC2 RHOG CCR7 PIK3R1 GRB2 OSM FGFR4 KLB PIK3AP1 TGFB1 CD86 IRS2 FGF2 IL18 ARRB2 RTN4 HSP90AA1 CD19 RET KIT FGFR1 NRG1	down	*
GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	0.0015600	0.0301797	0.4550599	0.3215054	1.501216	237	TP63 FOXM1 CHEK2 CCNB1 DDIT4 BRCA1 E2F8 GTSE1 L3MBTL1 AURKB TPX2 TFDP2 RBBP8 ACER2 CDK5RAP3 CASP2 EXO1 RHNO1 EEF1E1 AURKA ATR E2F2 MSX1 SMYD2 CDC25C SOX4 TOPBP1 CHEK1 MDM2 PRMT6 PERP BRIP1 BLM PML CNOT3 PLA2R1 DYRK2 ING4 CDK1 E2F1 DNA2 CNOT11 TAF6 PRKAA2 NOP2 STK11 TRIM24 CNOT2 FHIT RAD9A SSRP1 MYBBP1A HDAC1 NOC2L BCL2L12 CHD5 ATAD5 RAD50 SUPT16H TWIST1 RPA1 PRMT1 ANKRD1 TFAP4 PRMT5 MSH2 RFC5 TNKS1BP1 PAXIP1 CHD3 CDK5 TP53 TAF4 RAD1 E2F7 RRS1 MUC1 IFI16 PRKAG1 TTC5 RFFL PPP1R13L TOP3A PDK2 SPRED3 HINT1 ATRIP NPM1 BATF NDRG1 PCBP4 EHMT1 RMI1 ELL3 E2F4 TP53RK	up	*
GO_REGULATION_OF_LEUKOCYTE_MIGRATION	0.0022076	0.0376638	0.4317077	-0.2878099	-1.500090	163	HMOX1 SWAP70 GCSAML ADTRP SPN C5AR1 CD9 GAS6 IL23A RHOA APOD ANXA1 PLA2G7 ADA ADAM17 JAM3 CRK BST1 PTAFR THBS1 CCL3 SELP CCL4 JAM2 MIR24-2 XCL2 DUSP1 OXSR1 AKIRIN1 NCKAP1L IL6 LRCH1 RAC2 RHOG PTGER4 CCR7 DAPK2 DOCK8 CD74 FPR2 MIA3 CD81 LGALS3 KLRC4-KLRK1 CCR1 GPR18 ADAM10 CCL20 CCR6 ICAM1 EDN1 KLRK1 MTUS1 ANO6 GREM1 SERPINE1 C5AR2 CX3CR1 C5 TREM2	down	*
GO_CYTOPLASMIC_SIDE_OF_MEMBRANE	0.0019606	0.0347363	0.4317077	-0.2895772	-1.499196	152	PRMT8 AJAP1 AKAP5 STAC FYN SHANK3 FGR RHOA KCNAB1 ATP2B1 GM2A GNGT2 LITAF CAV2 PPP3CA GNG7 TRAF6 EPM2AIP1 DIABLO BIRC2 CDIP1 PTPRC GNAQ GNAI2 GNRH1 HCK DNAJA1 PALM FERMT2 SNX9 PTP4A1 PKD2 GNAI1 GNG5 EXOC1 GNA13 RGS2 GEM FKBP1A RAB5A TIAM1 ESYT1 TRAF1 SRMS KIT PTEN CYTH1 IQGAP1 HTRA2 CNR2 SPPL2A	down	*
GO_REGULATION_OF_CHROMOSOME_ORGANIZATION	0.0010272	0.0226786	0.4550599	0.3149434	1.497360	286	TRIP13 DDX11 CDC45 BUB1B NEK2 CCNB1 CENPF NDC80 PIF1 BRCA1 TTK DNMT3B NABP2 PLK1 AURKB PTTG1 WDR70 ESPL1 CDC6 MCM2 CCT6A CDT1 CCT2 SPDL1 RUVBL2 SDR16C5 MKI67 BUB1 TOP2A CCT5 ATR TPR MAD1L1 CDCA5 SETDB1 MORC2 ZNHIT1 CHEK1 MAD2L1 XRCC1 PIH1D1 PRMT6 PML NAA40 TADA2A MNAT1 PARP1 ANAPC5 CCT3 FEN1 TRAPPC12 MAD2L2 KLHL22 DNMT1 CDC23 DLGAP5 SMG5 TACC3 HIRA FBXO4 AKAP8L NOC2L ANAPC1 SLX4 ZBTB7B CCT7 RAD50 KDM3A TADA3 CENPV PPHLN1 CDC20 YLPM1 TWIST1 HMGA1 ALKBH4 CDK5RAP2 PYGO2 NSD1 PRKD2 ZNF274 ATAD2 RTEL1 MLLT6 NOS1 PAXIP1 SIRT6 PNKP LIF BCL6 CENPE TP53 SMARCB1 ATF7IP NAT10 MUC1 SART3 SETD5	up	*
GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION	0.0018037	0.0332048	0.4550599	-0.2893420	-1.495917	160	PHACTR1 DLC1 WNT4 GPR65 ARHGEF15 TMOD3 INPP5K BAG4 S1PR1 PRKAR1A MEF2A CDC42 EPB41L3 CIT RHOA MYOZ1 CSRP1 RGCC SFRP1 TCAP CNN1 SORBS3 EPB41L2 ROCK2 ARRB1 SORBS1 ROCK1 MYH11 LMOD3 SRF TMOD1 WASF2 PDCD6IP ARHGEF10 PTGER4 PIK3R1 PPM1F WNT11 CLASP2 ACTN2 WDR1 EPB41L5 LMOD1 TMOD2 LIMCH1 CUL3 RAPGEF3 EDN1 EPB41L4A SYNPO2L CNN2 SMAD4 CFL2 MYH10 FHOD1 ITGB1 ZYX CDC42BPB PPFIA1 TRPM7 LDB3	down	*
GO_SECOND_MESSENGER_MEDIATED_SIGNALING	0.0001458	0.0051665	0.5188481	-0.2595482	-1.494812	314	RAMP3 TMEM100 MCOLN1 EDNRB LHCGR ADCY9 GPR65 ADCY4 RAPGEF2 RAMP2 JPH4 CCRL2 CALCRL CDH13 ADRA1D ADCYAP1R1 INPP5A TBXA2R PRKAR1A RXFP1 CD22 NFATC3 PDE2A CD36 JPH2 MYOZ1 MCTP1 ADA RAPGEF4 NMUR1 CAMTA1 PEX5L ADRB1 PPP3CA ADRB2 PDE4D TMEM38B PPP3CC PTGIR BST1 THBS1 CCL3 PDE3B PTPRC SELP CCL4 PTGER3 UBE2B PLEK ZMPSTE24 HTT GNAQ GNAI2 CALM2 PTH1R S1PR4 SLC8A1 PPP2CA ADCY2 GPR61 NDNF HRH1 ADRA1A PDE5A JPH1 RCAN1 GSTO1 PTGER4 CCR7 ACKR3 PTGER2 NPR1 PRKACA PLCG2 GPR3 LMCD1 CALM1 PKD2 CCR4 FPR2 GNAI1 PPP3R1 CCR1 GNA13 RGS2 CCL20 CCR6 LAT FKBP1A CXCR4 CCR9 MT1M RAPGEF3 ADORA2A EDN1 PDE4A	down	**
GO_DRUG_BINDING	0.0000000	0.0000004	0.7881868	0.2902840	1.494608	1416	KIF1A ATP10B CPS1 KIF12 STYK1 TRIP13 HKDC1 ABCA13 DDX11 NPC1L1 ENTPD2 ABCC2 HELLS EPHB3 KIF20A DDX12P CYP19A1 GPT RUVBL1 AK4 DNAH2 GPT2 HBA1 CHEK2 BUB1B SLFN13 MYO3B HBA2 PPIP5K1 NEK2 XYLB FRK POLQ UBE2T PBK KIF18B TTF2 GUCY2C PIF1 CHRNG NMNAT3 IP6K3 STK36 TTK CDK4 BRSK1 SLC27A2 KIF14 UBE2Z ABCA12 GMPS STK31 FLAD1 CHRNA7 PLK1 AURKB ALDH18A1 PAK6 SLC6A3 CDC6 WNK2 TRIB3 FIGNL1 MCM4 PRKCA MCM2 RAD54B TYMS DNAH3 PMS2 NWD1 GLDC XRCC2 ORC1 AACS HBB CCT6A MCM8 PIP4K2C LIG3 MAP2K6 SGK2 SRPK1 KIF27 SHMT2 MOCOS INSRR EPHB1 P2RX2 DNAH14 MPPED2 AOC1 CCT2 DPYS AGK AK8 CYP3A5 NME1 IKBKE AARS2 TTLL4 RUVBL2 MELK DYRK1B KIF23 MKI67 CUL9 SLFN5 HLTF KIF15 PCCB MAP3K13 KIF3B BUB1 TOP2A CCT5 AURKA MYO10 ATR LARS2 SMARCAL1 KIF2C MCM7 COASY ABCC5 TTLL12 PRKDC RHOBTB3 SGPL1 GCAT HELB RAD54L PKM SBK1 EIF2AK1 PHKG2 KIF11 PASK MCM3 PEX6 MCCC2 TARS2 CHD6 EGFR DNAH8 LIG1 SARS2 RIPK4 MORC2 ABCB6 CHEK1 NEK11 ASS1 ACSF2 KIF3C EPHA10 PFKP ABCB9 HSP90AB2P MST1R KCNJ11 KHK AKT2 OXER1 PKMYT1 DNAH11 BRIP1 DDR1 CAD BLM PPP5C ATAD3C GLE1 ERCC2 TRPV4 MYO1A TRIT1 RECQL5 DYRK2 DDX56 PPIL1 MARK1 TNIK IKBKB DCLK1 TTBK1 CBWD6 FASTK NSF DDX51 MB HARS2 PAK1 LRGUK CDK1 CDK12 DNAH6 EPHA1 LRP2 PPIC KIF5A UCK2 MERTK STK32A CCT3 ATP2A1 TTLL9 TNK2 GOT2 NAV2 OAT DHX37 TRAP1 ABCC11 SYN3 MAP3K10 KIF19 DNA2 ACTR3C KIF2A DHX33 ACSBG2 KIF7 ITPKA KSR2 PDK1 NEK5 ACTR3B METTL3 SMO MYO5B AK7 ATAD3A DNAH5 PRKAA2 ABCA4 UCKL1 PSMC4 RTCB RECQL4 MAST1 ACVR1B STK11 TEP1 ITPR3 ULK1 DHX34 HSPA4L NMNAT2 MYO19 PARS2 MOV10 ANKK1 ILF2 CDK3 ATP7B DCAKD NEK10 NADK2 NFS1 SPG7 DNAH7 DHX40 GALK2 TRMU MTOR GSS DNAJA3 ATP9A AARSD1 LONP1 DHODH TRIO KIF22 MAPK13 RAD51D EPHB2 UBE2Q1 TK1 DTYMK CHTF18 SCN8A KIF21A CSNK1G1 LMTK2 SLC22A5 HSP90B2P GRIN3B MAPK10 TSSK3 XPR1 KIF20B NDUFA13 ASNS GK5 CHD5 CDK13 TTLL10 TWF1 ACSL6 TYRO3 ATAD5 MAT1A ATP13A1 NADSYN1 CCT7 CDC7 IP6K2 YARS2 RAD50 ABCC10 TNK1 EP400 PFAS UBE2O ABCC9 ENTPD8 DGKA IARS2 ERBB3 FTCD TTLL3 ACLY FIBCD1 ENTPD3 ABCC3 PHYKPL ABCA7 FANCM MCM6 MYO5C CKMT2 WRNIP1 DYNC1LI2 KIF21B CDC42BPG PRMT1 SRPK2 DHX8 MCM5 NMNAT1 ZRANB3 DDX23 DYNC2H1 NEK4 LANCL2 SCYL3 CUBN CHRNA3 CYP2D6 ADCK1 PIP5K1A MYH7B PFKFB4 LRRK1 TTLL6 IGHMBP2 MYH3 MAB21L1 MUSK ABCD4 PALM3 PRKD2 STK39 PI4KA GAD1 STK35 CHRNA5 DDX55 ATAD2 FARSA MYH13 ROS1 MSH4 SUV39H2 PMS1 ATP6AP1 MSH2 MAP3K14 ADCY1 SMARCA4 ULK4 STK38 DDX54 ABCF3 RTEL1 CDC42BPA RFC5 CSNK1G2 NME4 PAK4 ICK ABCF2 ACSF3 NUBP2 DNAH1 HK2 BMS1 RAD51 HLCS FARSB STK25 MAP3K9 PFKM NOS1 CHRFAM7A MARK4 SNRNP200 NME7 CHD3 CDK5 POMK ERBB2 NUBPL SMC2 PNKP ADCY6 CENPE HBG2 EIF4G1 GNE SRCAP EARS2 MYO15A DDX52 HSPA7 GLYCTK MTHFD1 TP53 CBWD1 TSSK4 SEPHS1 PAICS TIMM44 SIGMAR1 PPIA EPHB4 UBE2C NPR2 RIPK3 ADCK2 OAS3 PI4KB NAT10 TK2 TTLL5 BRSK2 KIF24 MOK ALPK1 DDX41 MAP3K19 MAP2K2 GRIN1 ACSL5 NLRC5 ERCC3 PRKAG1 ROR2 SLFNL1	up	***
GO_PYRUVATE_FAMILY_AMINO_ACID_METABOLIC_PROCESS	0.0003926	0.0112050	0.4984931	0.9900062	1.491220	2	GPT GPT2	up	*
GO_REGULATION_OF_T_CELL_ACTIVATION	0.0002528	0.0080074	0.4984931	-0.2668917	-1.490117	267	SIRPB1 CD55 SPN IL1B FYN CAV1 PRKAR1A CDC42 TGFBR2 IL23A RHOA ANXA1 CD5 ADA MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 ZEB1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 SLC46A2 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SFTPD SMAD7 IL7R CYP26B1 HES1 GNRH1 NCKAP1L CD80 IL6 CD160 PDE5A RAC2 CCR7 PIK3R1 CD83 GRB2 MALT1 RC3H1 DOCK8 AP3B1 TBX21 ZNF683 TIGIT PELI1 RUNX3 TREX1 CD74 CR1 CD1D ZBTB1 CD6 LRRC32 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1	down	**
GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION	0.0015887	0.0304054	0.4550599	-0.2837160	-1.490090	178	LIMS2 AJAP1 ACVRL1 FOXF1 TEK DLC1 ATXN3 WNT4 EMP2 CORO1C MYADM CDH13 CDC42 NEDD9 RHOA APOD CD36 ITGA5 FZD4 CRK SFRP1 ROCK2 DUSP3 NPNT PTPRO LIMS1 BST1 ROCK1 THBS1 PEAK1 NINJ1 KANK1 FAM107A UTRN NDNF NOTCH1 RAC2 MAP4K4 CCR7 PIK3R1 PRKCE HSD17B12 PPM1F EPHA3 CLASP2 MACF1 SPOCK2 ABI3BP UNC13D ARPC2 EPB41L5	down	*
GO_TUBULIN_BINDING	0.0010591	0.0229576	0.4550599	0.3139214	1.489667	282	KIF1A KIF12 KLC3 KIF20A MDM1 KIF18B BRCA1 RACGAP1 BRSK1 KIF14 CEP70 PLK1 GAPDH PRC1 DYNC1I1 KIF27 WDR90 NME1 TTLL4 KIF23 KIF15 KIF3B MAP10 CCT5 TPR KIF2C AGBL4 TTLL12 MAP1LC3C PDCD5 FSD1 HOOK1 KIF11 GAS8 KIF3C CLIP3 SPAG8 PPP5C ALDOA TRPV4 PSRC1 NUSAP1 KIF5A CENPJ BIRC5 JAKMIP1 KIF19 KIF2A KIF7 CCDC88C SPAG5 MAST1 VBP1 SPEF1 VPS41 ADNP KIF22 RAD51D DNM1 KIF21A GAS2 S100A9 MAP6D1 KIF20B POLB TRAF3IP1 FTCD EFHC1 CDK5RAP2 KIF21B EML6 TBCA FAM161A STMN3 KATNB1 SKAP1 TTLL6 HAUS4 NEFH STRBP ALMS1 APC2 JAKMIP3 TUBGCP4 SYBU CCDC181 HOOK2 CCDC88B MARK4 AGBL5 BCAS3 CAMSAP3 CENPE MAP1LC3A GOLGA2 DCDC1 MAP9 DNM1L CLASP1 KIF24	up	*
GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS	0.0025047	0.0410723	0.4317077	0.3231222	1.486763	206	AK4 ELOVL6 GPAT2 ACMSD GUCY2C NMNAT3 GMPS FLAD1 TYMS UMPS GUCA1B AK8 TAMM41 NME1 IDO1 COASY RRM2 NME9 PKM NME5 CAD IDH2 ALDOA PARP1 UCK2 ATIC SLC25A13 ACSBG2 PDK1 AK7 UCKL1 QPRT NMNAT2 UPP2 DCAKD NADK2 SLC26A2 DHODH TK1 DTYMK AGPAT5 LCLAT1 ACSL6 PARP9 NADSYN1 RAD50 SLC26A1 PFAS ENTPD8 STOML2 ACLY PPCDC NMNAT1 LHPP ME1 ADCY1 NME4 ACSF3 ELOVL4 COX5B NOS1 NME7 VPS9D1 SLC35B3 PNKP ADCY6 MTHFD1 PAICS NNMT PDP1 RNLS NPR2 ENO1 TK2 ACSL5 ACSBG1 NOS3 DGUOK SPHK2 PDK2 ADSL APRT PANK4 PRPSAP2 AK9 SHMT1 NADK PARP16 CMPK2 AFMID HAAO	up	*
GO_RESPONSE_TO_GROWTH_FACTOR	0.0000025	0.0002053	0.6272567	-0.2480106	-1.485281	578	SMAD6 TRIM71 SEMA6A TMEM100 ACVRL1 SOSTDC1 HHEX SFRP4 IL1B CLEC3B CAT WNT4 P2RY1 GREM2 RDX RAPGEF2 BMPER RAMP2 BMP2 CDH5 ENG KL BDNF FOLR1 FYN CD44 INPP5K BAG4 CAV1 BAIAP2 CITED2 TBC1D7 BMPR2 FGF10 MIR27B NR3C1 TGFBR3 GAS6 CBL TGFBR2 IER2 RHOA PDE2A TMPRSS6 ANXA1 MIR146A MMRN2 LTBP4 ADAM17 RAP1A TMEM204 ITGA5 HSPB1 NLK FZD4 CAV2 GATA3 NR4A1 CRK SFRP1 SPRY2 ZFYVE16 ZEB1 UBE2D3 RAB14 NODAL PTPN12 IL10 MAP2K3 ROCK2 PRDM16 DUSP3 SDCBP NPNT LIMS1 KLF4 ZNF423 ROCK1 DAB2 THBS1 CLDN5 PDE8A CEP57 SMAD7 VEPH1 NUS1 HES1 HTRA4 MIR17HG ANXA3 TGFB2 NRROS RBPJ MYO1C FLT1 ADAMTSL2 APPL1 MAGI2 JUN NOTCH1 LTBP2 BMP3 SHOC2 RAPGEF1 FERMT2 SKIL DDX5 GRB2 CREB1 FSTL3 NDST1 FGFR4 FOS SPRY4 UBB KLB RUNX3 SORT1 TGFB1 EHD1 PARD6A TGIF1 ZFYVE9 MIR23A TGFB1I1 LRRC32 MYOCD TOB1 NPTN GATA6 LTBP1 SMAD2 LDLRAD4 FGF2 EPB41L5 EPN2 ARRB2 ACAP2 CDKN1C UBE2D1 EPHA2 CREBBP ING2 GTF2F2 EDN1 ETV2 PTEN SKI LTBP3 KIF1B FGFR1 NRP2 GRB10 IQGAP1 EHD4 SMAD4 FEZ1 FLT4 SPHK1 SKOR1 HNRNPH1 ADAMTS7 ARHGEF18 SETX HTRA2 ACVR1C EGR1 GREM1 DUSP6 DKK3 CX3CR1 MAPK1 ZYX HAS2 ZFP36 CD109 NOG	down	***
GO_SKIN_DEVELOPMENT	0.0021220	0.0364487	0.4317077	0.3221904	1.484184	208	DKK1 PCSK6 TP63 LIPM KRT5 PKP2 PKP1 FOXE1 FA2H ABCA12 KRT16 SOX9 SLITRK5 CYP27B1 LSR GRHL3 FERMT1 KRT15 ITGA2 CLDN1 HRNR MSX2 ITGB4 FLG NSUN2 TGM1 EGFR ABCB6 PERP GRHL2 FLNB ERCC2 IGFBP5 KRT18 VANGL2 GJB3 COL3A1 CDH3 TMEM79 NF1 SMO ACVR1B IRF6 LGR5 ST14 COL1A1 COL1A2 ALX4 TRIM16 CTSV TRADD PKP3 COL5A2 HDAC1 PKP4 KRT19 PPHLN1 WNT10B KRT8 COMP COL5A3 SPINK5 EDAR PIP5K1A OVOL2 KRTAP5-9 PRSS8	up	*
GO_CELLULAR_RESPONSE_TO_PEPTIDE	0.0001220	0.0044808	0.5384341	-0.2566625	-1.483798	310	LPIN2 PPARG CPEB2 IL1B LHCGR ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A CD36 MIR146A ATP2B1 ANXA5 KLF10 CAV2 ADIPOR1 NR4A1 ADRB2 NFE2L2 NDEL1 CRK ARHGEF2 ATP6V1H ATP6V1B2 FOXC2 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 KLF4 ROCK1 KLF11 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 VIM ATP6V0D2 TLR4 PIK3C2A GNAI2 TBC1D4 BACE1 SLC25A33 PDK4 KANK1 MYO1C ADCY2 PSEN1 SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ KLF2 FOXO3	down	**
GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS	0.0000000	0.0000046	0.7337620	-0.2403728	-1.480825	889	TNR LIMS2 ANGPT4 DAB1 SEMA6B AJAP1 SEMA3G SEMA6A TMEM100 ACVRL1 WTIP IL1A SASH1 HMOX1 TEK DLC1 FGD5 PPARG HHEX GATA2 IL1B TIE1 DCSTAMP WNT4 P2RY1 EMP2 RDX DPYSL2 RAPGEF2 BMPER RAMP2 PID1 BMP2 TRPV2 CDH5 ENG BDNF FYN SHANK3 CD44 ECSCR CORO1C MYADM NEDD4L BAIAP2 CITED2 BMPR2 GTF2I CDC42EP2 TBXA2R C5AR1 FGF10 CDC42 MIR27B NEDD9 IL1RN PSMD5 EPB41L3 TGFBR2 HSPG2 FGR RHOA ZEB2 SEMA6D CD36 ANXA1 TBX2 MIR146A MMRN2 PTPRM SEMA3B ADA TTL FOXA2 HECW2 WNT2B RAP1A PLXNA2 ITGA5 HSPB1 FZD4 FOXP1 GATA3 PPP3CA ZMYM6 PLXNA4 RGCC ISLR2 NFE2L2 NDEL1 GRN CRK SFRP1 AKT3 SPRY2 WNT3A ITSN2 PDGFA FOXC2 NODAL CST3 ATP10A RHOB LRP4 GPR4 IL10 AGO4 ROCK2 NRARP PTPRO LIMS1 ZSWIM6 TRIM46 TNFSF12 TSPAN12 KLF4 ROCK1 DAB2 PARVB THBS1 ADAMTS9 CLDN5 MPL SEC24B TMBIM1 FMNL3 CCL3 PDE3B ITGAX ARC MIR24-2 RECK SS18L2 CD53 WASF3 PIK3C2A ZMPSTE24 PINK1 TBX5 PRICKLE2 PAFAH1B1 PTGIS RUFY3 HES1 ANXA3 ACTR2 TGFB2 HEXB HCK SRF BTG1 KANK1 RBPJ FMNL2 CNTF FLT1 IL6 CD160 DDHD1 PSEN1 MAGI2 PSMA1 VAT1 NOTCH1 RHOBTB2 LIMD1 ETS1 RAC2 TYROBP RHOG JAK1 RHOJ PALM FERMT2 SKIL IFRD1 NPR1 RC3H1 RTN4R ZNRF3 TRAK2 PALMD CD34 POGLUT1 RHOQ RRAS KLF2 MBP PSMD12 EHD2 SRSF6 WNT11 BTBD7 TGFB1 EPB42 EHD1 PARD6A DDHD2 ISM1 ZRANB1 HECW1 MIR23A PIM1 CLASP2 GATA6 GNA13 MACF1 PLAA ADAM10 IST1 RXRA UNC13D ICAM1 FGF2 PDLIM5 ARPC2 VASH1 WDR1 EPN2 ARRB2 OSR1 SEMA4A RTN4 CDC42EP3 TIAM1 CXCR4 EPHA4 ARHGAP18 SP100 BRWD1 PSME4 EPHA2 RND1 ULK2 PARVA GLUL SIN3A RET RAPGEF3 KIT EDN1 FOXJ2 PTEN	down	***
GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION	0.0003737	0.0107577	0.4984931	-0.2626401	-1.480667	283	HCRTR1 GPR17 RAMP3 CD52 SWAP70 MCOLN1 EDNRB CD55 GATA2 F2RL3 P2RY1 GPR65 TRPC3 FYN JPH4 CCRL2 CAV1 ADRA1D GTF2I ADCYAP1R1 TBXA2R C5AR1 S1PR1 CD36 JPH2 ATP2B1 KCNK3 MS4A1 PDE4D TMEM38B GPR4 SYNPO PTGIR CCL3 PTPRC PTGER3 HTT GPR157 UBASH3B CALM2 PLCD1 PTH1R KCNA5 S1PR4 SLC8A1 PDE6A PDE6B ADRA1A JPH1 GSTO1 PTGER4 CCR7 ACKR3 PRKCE PTGER2 GRIA1 PRKACA CLN3 PLCG2 CALM1 PKD2 CCR4 FPR2 SLC8A3 CCR1 NPTN GNA13 GPR18 CALB1 CCR6 FGF2 ABL2 FKBP1A CXCR4 CCR9 BOK CD19 EDN1 MCOLN2 P2RX1	down	*
GO_RESPONSE_TO_CYTOKINE	0.0000000	0.0000006	0.7749390	-0.2388090	-1.479604	953	GPD1 CXCL3 GPR17 EREG ACP5 KMO CD300LF IL17RB IL1A FOXF1 HMOX1 CXCL16 PPARG IL1B FABP4 MNDA SNX10 DCSTAMP GREM2 PLA2G10 PID1 FYN CD44 PDE1B CCL3L1 SOX17 CCRL2 INPP5K SAMHD1 ST3GAL6 BAG4 CAV1 FOSL1 MYD88 CDC42EP2 SRSF7 PCOLCE2 S1PR1 CDC42 IL1RL1 IL1RN GAS6 OTUD4 PSMD5 CBL SLC11A1 IL23A RHOA PDE2A CD36 ANXA1 MIR146A TNFRSF8 SSTR1 SH2B3 CLCF1 CARD16 FOXA2 ADAM17 LIFR ASAH1 MAP3K8 IFI30 FZD4 LCP1 IFNK ADIPOR1 GATA3 SIRPA IL18R1 TRAF6 NFE2L2 HNRNPDL CRK SFRP1 SPRY2 ZEB1 ARHGEF2 HNRNPU SPI1 TFRC MCL1 MTHFR CD58 PTPN12 IL10 STAT5A CCL22 TLE4 RAB12 FOXO1 BIRC2 EPOR NPNT MEFV CASP1 LIMS1 TNFSF12 YBX3 PTAFR KLF4 CDIP1 TNFSF15 THBS1 CEBPA STX3 SOCS2 CDK9 VRK2 SOCS5 MPL CCL3 LAPTM5 NFKB1 PMM1 CDKN1A ITGAX PTPRC CXCL2 IRAK2 VIM AQP4 AXL CCL4 TLR4 MIR24-2 ACTR3 XCL2 TAF9 FCER1G DUSP1 SMAD7 ADIPOR2 MPC1 OXSR1 IL7R PAFAH1B1 PRDM5 BCLAF1 CA1 PTGIS HLA-DQA1 IL24 AFF3 ACTR2 PIAS1 HCK SRF MYO1C CREBRF VAMP3 CD80 CNTF ELF1 IL6 YBX1 SOCS3 IL2RB APPL1 OASL SRSF3 ETV3 JUN PSMA1 CCDC3 LRCH1 STAT4 ETS1 CARD8 HSPA1B DUOX1 JUNB IFNGR1 JAK1 RAPGEF1 GSTO1 CCR7 SKIL PIK3R1 ACKR3 IRF8 GRB2 CREB1 OSM RC3H1 REL PRKACA DOCK8 CXCL5 TCP1 TNFRSF9 YWHAZ GFPT2 ACSL1 FOS UBB PELI1 KLF2 CACYBP TNFSF13 YTHDF3 PSMD12 FOXO3 MAPK8 TREX1 CD74 ZFAND6 MME CCR4 IRF5 TIMP2 UBXN2A STXBP3 TGFB1 HNRNPA2B1 TEX14 TEC YTHDF2 PDE12 IFNAR1 CD86 IRS2 CNOT7 PIM1 SOD2 CCR1 KYNU PGGT1B SPOCK2 ADAM10 IFNLR1 CCL20 PITPNA JUND CCR6 ICAM1 SELPLG FGF2 IL18 IL18RAP TFPI CEBPD CXCR4 HSP90AA1 CALCOCO2 TAB2 RIPK2 CCR9 HSPA8 SP100 BRWD1 PSME4 TRAF1 DAPK1 NFKBIA KIT TIMP3 EDN1 PAK2 B3GNT2 TNFSF9 AIM2 RORA NRP2 PSMD6 MT2A PSMD9 IL16 EIF4A2 CNN2 SMAD4 SPHK1 IRF2 CSF2 ADAMTS7 LRRC70 UBE2V1 CYBA HTRA2 EGR1 CD70 CSF2RB	down	***
GO_VACUOLAR_MEMBRANE	0.0001211	0.0044629	0.5384341	-0.2547319	-1.478517	341	SIDT2 MCOLN1 TMEM150B RAB44 SPNS1 THBD PCSK9 TMEM138 ARL8B SLC15A3 MANBA VAPA LAMP1 SLC44A2 MAN2B1 RRAGC SLC3A1 RILP LITAF CYB561A3 ANPEP CLN5 ABHD6 STOM GRN LAMTOR3 ATP6V1H RAB14 ATP6V1B2 CYBRD1 ARRB1 RAB12 AHNAK SLC12A4 CDIP1 DAB2 GAA DRAM1 MAP1LC3B ATP6V1D SPAG9 CTSD TMBIM1 LAPTM5 HPSE ATP6V0D2 M6PR TM6SF1 GNAQ HLA-DQA1 LMBRD1 CMTM6 PI4K2A HGSNAT PRCP TMEM9B GABARAPL2 PSEN1 ATP6V0B ATP11A OSTM1 STX7 GLIPR1 ENTPD4 AP3B1 UVRAG CLN3 TMEM192 SLC3A2 ATP6V0D1 CD164 NAPG CD74 SORT1 AP1G1 CD1D SBF2 MTMR2 GNAI1 ATP6V1A ATP6V0C GNB4 GABARAPL1 BRI3 VPS39 MFSD12 CLCN6 BLOC1S2 CALCOCO2 GIMAP5 HSPA8 SNAP29 MMD LDLR WDFY3 RNF13 RAB2A ZFYVE26 ATP6V0A1 SPPL2A TMEM30A ATP11B LNPEP SH3GLB1 RAB37 DRAM2 FPR1 SLC26A11 NFAM1 YWHAB WDR41 LAMP3 SNX14 HLA-DRB1 LAMTOR5 GPR137B	down	**
GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION	0.0000026	0.0002084	0.6272567	-0.2466585	-1.477145	550	SLC6A4 SMAD6 LIMS2 RBP4 EREG ACVRL1 IL1A HMOX1 DLC1 KLF13 PPARG GATA2 SFRP4 SPN WFDC1 IL1B MNDA RAPGEF2 BMP2 CDH5 CCL3L1 CAV1 FOSL1 CDH13 BMPR2 FGF10 PRKAR1A TGFBR3 CD9 TGFBR2 PPM1D TRIB1 APOD MIR146A TNFRSF8 SSTR1 SH2B3 PTPRM CD33 LMNA BTG2 ZNF503 KLF10 CAV2 IFNK DACH1 GATA3 RB1 RGCC SFRP1 SPRY2 BNIPL KANK2 ZEB1 SOX7 BTG3 KRT4 NODAL CNN1 ADARB1 IL10 PTGIR KLF4 REST KLF9 KLF11 THBS1 CEBPA BCHE NPR3 PER2 CDKN1A ID2 MIR24-2 SFTPD DUSP1 RNF139 INHBA PPP2R5C TBX5 ADAMTS8 HES1 MIR17HG IL24 AKIRIN1 PTH1R TGFB2 GNRH1 SRF BTG1 RPS6KA2 RBPJ WNT9A PRKRA CD80 FLT1 IL6 DDX20 PODN MAGI2 ETV3 JUN HPGDS NOTCH1 ETS1 ADRA1A PDE5A TYROBP HSPA1B RAPGEF1 OSM NPR1 RC3H1 MORC3 TNFRSF9 TINF2 PELI1 CD164 RUNX3 PKD2 EPPK1 WNT11 TIMP2 SAV1 TGFB1 PBRM1 STRN PDS5B TGFB1I1 CBFA2T3 LRRC32 CD86 TBRG1 CNOT7 SOD2 MEIS1 MYOCD TOB1 KAT2B TSPO IFNLR1 SMAD2 NR2E3 VASH1 CGRRF1 SF1	down	***
GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE	0.0000164	0.0009466	0.5756103	-0.2541023	-1.476168	406	SLC6A4 TNR SEMA6B SEMA3G SEMA6A HMOX1 SWAP70 SLC12A6 ACE EDNRB P2RY1 RDX DPYSL2 TRPV2 BDNF SHANK3 TMOD3 BAG4 KANK3 CAV1 MYADM BAIAP2 ADRA1D BMPR2 CDC42EP2 ESAM TBXA2R HMGCR CIT RHOA SEMA6D ATP2B1 PTPRM SEMA3B RILP TTL PICALM SPIRE1 ADRB1 PLXNA4 TMEM123 ADRB2 ISLR2 NDEL1 SPTBN1 WNT3A FOXC2 ROCK2 KCNMA1 TRIM46 PTAFR SLC12A4 ROCK1 VASP PER2 COTL1 P2RY2 KCNMB1 AQP4 ACTR3 CAPZA2 PIK3C2A PLEK DSTN RAP1GDS1 IL7R PAFAH1B1 RUFY3 ADD1 ACTR2 LMOD3 HCK MTPN CLN8 SRF NCKAP1L KCNA5 KANK1 MYO1C SLC8A1 TMOD1 HRH1 ADRA1A PPP1R15A CCR7 IFRD1 GMFG PRKCE GRB2 CREB1 NPR1 RTN4R	down	***
GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	0.0006155	0.0156722	0.4772708	-0.2673862	-1.475093	230	CD101 TAL1 GATA2 DCSTAMP GAS6 TGFBR2 TRIB1 LILRB3 IL23A RHOA ANXA1 FBXO7 ADA KLF10 FOXP1 HLX GATA3 RB1 TRAF6 SFRP1 ZEB1 ZMIZ1 EVI2B NRARP SLC46A2 SOCS5 CCL3 PTPRC AXL ID2 TLR4 SMAD7 INHBA IL7R UBASH3B CYP26B1 MIR17HG NCKAP1L CD80 JUN MITF CUL4A TYROBP PIK3R1 CD83 CREB1 MALT1 SIGLEC15 RC3H1 AP3B1 FSTL3 TBX21 RASSF2 ZNF683 FOS RUNX3 CD74 CR1 TGFB1 ZBTB1	down	*
GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY	0.0000017	0.0001507	0.6435518	-0.2436394	-1.472061	608	CXCL3 GPR17 EREG CD300LF IL17RB IL1A HMOX1 PPARG IL1B GREM2 FYN CD44 CCL3L1 CCRL2 SAMHD1 BAG4 CAV1 MYD88 S1PR1 CDC42 IL1RL1 IL1RN GAS6 OTUD4 PSMD5 CBL IL23A CD36 ANXA1 MIR146A TNFRSF8 SH2B3 CLCF1 CARD16 ADAM17 LIFR MAP3K8 IFI30 FZD4 LCP1 IFNK ADIPOR1 GATA3 IL18R1 TRAF6 HNRNPDL CRK ZEB1 SPI1 MCL1 IL10 STAT5A CCL22 FOXO1 BIRC2 EPOR CASP1 LIMS1 TNFSF12 PTAFR CDIP1 TNFSF15 CEBPA STX3 SOCS2 VRK2 SOCS5 MPL CCL3 NFKB1 CDKN1A ITGAX PTPRC CXCL2 IRAK2 VIM AXL CCL4 MIR24-2 XCL2 FCER1G ADIPOR2 OXSR1 IL7R PAFAH1B1 CA1 HLA-DQA1 IL24 PIAS1 HCK CREBRF CD80 CNTF ELF1 IL6 SOCS3 IL2RB APPL1 OASL PSMA1 CCDC3 STAT4 CARD8 HSPA1B DUOX1 JUNB IFNGR1 JAK1 RAPGEF1 GSTO1 CCR7 PIK3R1 ACKR3 IRF8 GRB2 OSM PRKACA CXCL5 TCP1 TNFRSF9 YWHAZ ACSL1 FOS UBB PELI1 TNFSF13 YTHDF3 PSMD12 FOXO3 TREX1 CD74 CCR4 IRF5 TGFB1 HNRNPA2B1 TEC YTHDF2 IFNAR1 CD86 IRS2 CNOT7 PIM1 SOD2 CCR1 IFNLR1 CCL20 PITPNA CCR6 ICAM1 FGF2 IL18 IL18RAP CEBPD CXCR4 HSP90AA1 TAB2 RIPK2 CCR9 HSPA8 SP100 BRWD1 PSME4 TRAF1 NFKBIA KIT EDN1 PAK2 TNFSF9 AIM2 RORA PSMD6 MT2A PSMD9 IL16 CNN2 SMAD4 SPHK1 IRF2 CSF2 UBE2V1 EGR1 CD70 CSF2RB GHR TNFSF8 SPPL2A	down	***
GO_IMMUNE_EFFECTOR_PROCESS	0.0000000	0.0000004	0.7881868	-0.2391953	-1.471139	986	POLR3H SIRPB1 RBP4 SLPI FOXF1 HMOX1 SWAP70 FCN1 OLR1 ACE SCIMP PECAM1 HVCN1 CD55 FCN3 GAPT GATA2 SPN PGC IL1B MNDA LTA4H CAT RAB44 EMP2 CLEC12A PTPRB OSCAR FYN CD44 SAMHD1 CLEC12B BAIAP2 PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 ELMO1 CDC42 MANBA CD1C VAPA FUCA1 LAMP1 CBL CD22 SLC11A1 LILRB3 RFTN1 IL23A CD8A FGR RHOA DNASE1L3 CD36 ANXA1 SLC44A2 CLCF1 DNAJC3 MAN2B1 IGKV2-28 ADA CD33 ARSB ADAM17 ASAH1 RAP1A GM2A MASP1 RNF125 FOXP1 ANPEP PTX3 HLX LCP1 IFNK SERPINB9 STOM LAIR1 GATA3 SIRPA RGCC IL18R1 TRAF6 CD93 GRN LAMTOR3 CRK CRTAM TFRC RAB14 CD58 CST3 ADARB1 IL10 FABP5 CFD BIRC2 SDCBP BST1 PTAFR PLAUR FUT7 ROCK1 GAA OSTF1 ATP6V1D SOCS5 FAM49B CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 CADM1 ITGAX PTPRC SELL HPSE TLR4 ARHGAP9 ACTR3 CD53 PRF1 FCER1G SMAD7 ZMPSTE24 GCA KLRD1 IL7R C4BPB DEGS1 ANXA3 CMTM6 ACTR2 TGFB2 GLB1 HEXB HCK HGSNAT RAB6A NCKAP1L PRCP IGLV2-11 MYO1C CD80 IL6 WASF2 CD160 CTSS PSEN1 SNAP23 APPL1 OASL SEC14L1 C1QA VAT1 RAB31 HK3 CTSZ RAC2 DDX17 TYROBP HSPA1B ATP11A RHOG RAPGEF1 PTGER4 STX7 ENPP4 GLIPR1 PIK3R1 GMFG PRKCE GRB2 GPR183 MALT1 RC3H1 SERPINB6 CAP1 SUCNR1 TBX21 ZNF683 IGKV3-20 PLCG2 TNFSF13 PSMD12 ALDH3B1 TREX1 CD74 KLRC2 BIN2 ZNF175 CR1 MME IRF5 TIMP2 STXBP3 SIGLEC14 TGFB1 VAV3 AP1G1 DOK3 CD1D ZBTB1 MILR1 SERPINB1 FPR2 PDE12 TSPAN14 CD86 DYNC1LI1 CNOT7 ATP6V0C GPR84 CD81 LGALS3 KLRC4-KLRK1 EXOC1 IGHV3-23 ORM2 BRI3 FCGRT MFNG PLEKHO2 ADAM10 SERINC3 IFNLR1 IST1 IGKV1D-39 COMMD9 UNC13D CCR6 ICAM1 BNIP3L IL18 IL18RAP LAT ARPC2 WDR1 NBN ARRB2 SEMA4A HSP90AA1 RIPK2 NLRP3 HSPA8 ACTB HAVCR2 METTL7A CD19 NHLRC3 SIN3A KIT SIGLEC9 CTSC CD1E DOCK10 CD3G ARPC5 KLRK1 LYST SNAP29 AIM2 P2RX1 RORA ITCH PSMD6 IQGAP1 CREG1	down	***
GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS	0.0001471	0.0051753	0.5188481	0.2978171	1.469634	491	CPS1 HKDC1 ENTPD2 AK4 GMDS ELOVL6 NUP107 SULT1C2 GPAT2 PRTFDC1 ACMSD PGM2L1 DDIT4 GUCY2C NMNAT3 THEM4 THEM5 GMPS FLAD1 GPI ACOT8 GAPDH SMPDL3A TYMS UMPS XDH ALDOC GUCA1B PDE9A SMUG1 DPYS AK8 TAMM41 NME1 DNPH1 NUDT1 DLG1 GFPT1 CARD11 IDO1 NUP155 TPR COASY RRM2 NT5C1B NME9 PKM ENTPD6 MCCC2 NUDT17 NME5 ACSF2 AHCY PFKP DCTPP1 CAD GNPDA1 IDH2 ALDOA ENTPD5 PARP1 GCKR LRGUK UCK2 ATIC UNG ALDOB DGAT2 SLC25A13 BPGM GNPNAT1 ENPP3 ACSBG2 PDK1 NUP205 OARD1 AK7 PRKAA2 UCKL1 QPRT EIF6 NMNAT2 MPI UPP2 ACBD6 FOXK1 DCAKD NADK2 SLC26A2 MTOR FHIT MBD4 DHODH TK1 DTYMK NUDT16 AGPAT5 LCLAT1 ACSL6 NUP85 PARP9 NADSYN1 NT5M SULT1B1 RAD50 DHTKD1 SLC26A1 PFAS TSTA3 ENTPD8 STOML2 AAAS ACLY ENTPD3 BAD PPCDC NMNAT1 ACOT11 SLC35A3 PTHLH PFKFB4 LHPP ESRRB NUP62 APOBEC2 ME1 ADCY1 AMDHD2 NME4 ACSF3 ELOVL4 HK2 SEC13 COX5B SULT1A3 PFKM NOS1 NME7 VPS9D1 SLC35B3 PGAM1 SIRT6 ENTPD7 PNKP PARG GMPR2 ADCY6 GNE MTHFD1 NEIL1 PAICS BPNT1 NNMT PDP1 RNLS NPR2 ENO1 NUP210 TK2 NUP93 ACSL5 PRKAG1 APOBEC3B ACSBG1 NOS3 ACSM3 DGUOK SPHK2 PDK2 GSK3A ADSL DPYD APRT HINT1 OPA1 PANK4 PRPSAP2	up	**
GO_POSITIVE_REGULATION_OF_CELL_CYCLE	0.0016761	0.0315035	0.4550599	0.3067619	1.469263	308	HMGA2 DDX11 CDC45 CHEK2 CCNB1 PAGR1 STOX1 NDC80 BRCA1 CDK4 SMPD3 RACGAP1 E2F8 GTSE1 DBF4B KIF14 AURKB ECT2 ESPL1 CDC6 TFDP2 PRKCA CDC25A DTL CDT1 RANBP1 CASP2 SMARCD3 KIF23 FOXA1 RHNO1 KIF3B LGMN MSX2 MAP10 GPER1 AURKA TPR MSX1 POC1A CXCR5 CDCA5 GPSM2 CDC25C SOX4 TGM1 EGFR CHEK1 MAD2L1 MDM2 PML CNOT3 MNAT1 STXBP4 PSRC1 CKS1B NUSAP1 ANAPC5 CDK1 CENPJ E2F1 FEN1 EZH2 CNOT11 SPAG5 EGF RAB11FIP4 MTBP GIPC1 CCNE1 DLGAP5 CNOT2 MTA3 MYBBP1A PKP4 NUDT16 KIF20B TRIM32 ASNS ATAD5 CDC7 ANKRD31 PROX1 SH2B1 CENPV	up	*
GO_POSITIVE_REGULATION_OF_HEMOPOIESIS	0.0019485	0.0346415	0.4550599	-0.2839583	-1.469261	162	CD101 TAL1 GATA2 DCSTAMP GAS6 TGFBR2 TRIB1 IL23A RHOA ANXA1 ADA KLF10 HLX GATA3 RB1 TRAF6 ZMIZ1 EVI2B SOCS5 MPL PTPRC AXL ID2 INHBA IL7R NCKAP1L CD80 JUN ETS1 TYROBP HSPA1B ATXN1L CD83 CREB1 MALT1 AP3B1 FOS RUNX3 FOXO3 CD74 TGFB1 ZBTB1 CD86 CCR1 N4BP2L2 IL18 RIPK2 NLRP3	down	*
GO_REGULATION_OF_LIPID_METABOLIC_PROCESS	0.0002688	0.0084328	0.4984931	-0.2552984	-1.467465	323	SC5D ABHD5 TEK PPARG IL1B WNT4 BMP2 SIK1 INSIG1 HCAR2 CAV1 IDI1 HMGCR ALAS1 CDC42 MIR27B CYP4A11 FGR APOD CD36 ANXA1 STARD4 LACTB ASAH1 ABCG1 ADIPOR1 ABHD6 RB1 APOC1 PDGFA FABP5 SNAI1 SORBS1 ACSL3 KLF4 REST SOCS2 SOCS5 NFKB1 PDE3B NR1D2 ID2 ZMPSTE24 CPT1A ADIPOR2 PPP2R5A PIK3R5 NRBF2 NCOA1 PDK4 FLT1 NSMAF DDX20 HSD17B13 SOCS3 DHH CCDC3 MTMR9 CCR7 GLIPR1 PIK3R1 PRKCE CREB1 PANK2 FGFR4 ACSL1 PNPLA2 TREX1 CD74 TGFB1 VAV3 FPR2 MTMR2 IRS2 NFYC CD81 CPT2 ACADL TSPO RXRA RBL2 FGF2 SF1 ORMDL1 ACACB CREBBP CD19 SREBF2 SIN3A ACADM KIT FDFT1 RORA LDLR	down	**
GO_MYELOID_CELL_DIFFERENTIATION	0.0000867	0.0034199	0.5384341	-0.2531524	-1.465321	334	EPAS1 CLEC1B CD101 TAL1 KLF13 PPARG GATA2 SNX10 DCSTAMP OSCAR PDE1B TMOD3 CDC42 TGFBR3 TET2 TGFBR2 TRIB1 LILRB3 IL23A CASP9 SH2B3 RASGRP4 KLF10 FOXP1 ASH2L GATA3 RB1 TRAF6 SFRP1 SPI1 TFRC FLI1 EVI2B AGO4 AGO3 THBS1 CEBPA MPL CCL3 ID2 TLR4 FCER1G LYAR INHBA UBASH3B PAFAH1B1 ADD1 SRF NRROS NCKAP1L RBPJ WASF2 PKNOX1 PSEN1 JUN MITF GABPA CUL4A ETS1 TYROBP HSPA1B JUNB OSTM1 DNASE2 CCR7 SP3 PIK3R1 PABPC4 IRF8 GPR183 CREB1 SIGLEC15 FSTL3 RASSF2 SNRK FOS KLF2 FOXO3 KAT8 CD74 TGFB1 EPB42 JMJD6 CBFA2T3 CD81 LGALS3 MEIS1 CCR1	down	**
GO_SIDE_OF_MEMBRANE	0.0000131	0.0007919	0.5933255	-0.2524199	-1.465261	431	PRMT8 AJAP1 AKAP5 STAC FCN1 ACE PECAM1 GPIHBP1 BTNL9 CDH5 ENG PCSK9 FOLR1 FYN SHANK3 CCRL2 CLEC12B CDH13 S1PR1 TGFBR3 IL1RL1 CD1C CD9 LAMP1 TGFBR2 ABCB1 CD8A FGR HEG1 RHOA KCNAB1 CD36 ANXA1 ATP2B1 CD5 ADA CD33 LIFR GM2A ABCG2 GNGT2 ITGA5 CLEC14A ANXA5 LITAF ABCG1 ANPEP CAV2 MS4A1 PPP3CA GNG7 TMEM123 TRAF6 EPM2AIP1 TFRC DIABLO BIRC2 CDIP1 THBS1 ABCC4 PTPRC AQP4 SELL SELP TLR4 FCER1G KLRD1 GNAQ IL7R GNAI2 HLA-DQA1 GNRH1 HCK CD80 IL2RB DNAJA1 PALM FERMT2 CCR7 ACKR3 CD83 RTN4R TNFRSF9 MCAM CD34 SNX9 PTP4A1 PKD2 CD74 CCR4 CD1D CD6 GNAI1 CD86 PDCD1 GNG5 GLRA1 KLRC4-KLRK1 EXOC1 IGHV3-23 CCR1 FCGRT GNA13 RGS2 MR1 CCR6 GEM ICAM1 FKBP1A RAB5A TIAM1 CXCR4 ESYT1 ITGAE CCR9 HSPA8 BCAM TRAF1 CD19 SRMS KIT CD1E CD3G SCUBE1 KLRK1 PTEN CYTH1 P2RX1 LDLR IQGAP1	down	***
GO_MESENCHYMAL_CELL_DIFFERENTIATION	0.0008274	0.0194555	0.4772708	-0.2774245	-1.463646	185	SEMA6B SEMA3G SEMA6A TMEM100 EDNRB GLIPR2 IL1B WNT4 BMP2 ENG FOLR1 CORO1C FGF10 TGFBR3 TGFBR2 ZEB2 SEMA6D SEMA3B FOXA2 ADIPOR1 RGCC SFRP1 TCF7L2 FOXC2 TAPT1 SNAI1 SDCBP DAB2 SMAD7 TBX5 PEF1 HES1 TGFB2 RBPJ PPP2CA IL6 NOTCH1 DDX17 DDX5 KBTBD8 WNT11 EPHA3 TGFB1 TGFB1I1 CLASP2 SMAD2 LDLRAD4 EPB41L5 OSR1 SEMA4A RTN4 TIAM1 S100A4 RET EDN1 PTEN FGFR1 NRP2 NRG1 SMAD4	down	*
GO_POSITIVE_REGULATION_OF_TOOTH_MINERALIZATION	0.0031879	0.0485812	0.4317077	0.9705934	1.461979	2	TFAP2A ENAM	up	*
GO_ACTIN_FILAMENT_ORGANIZATION	0.0002528	0.0080074	0.4984931	-0.2543179	-1.456587	319	SWAP70 PHACTR1 DLC1 WNT4 EMP2 RDX GPR65 ARHGEF15 SHANK3 TMOD3 CGNL1 INPP5K BAG4 KANK3 CORO1C MYADM BAIAP2 CDC42EP2 ESAM S1PR1 CDC42 NEDD9 CIT RHOA CORO6 SPIRE1 LCP1 RGCC SFRP1 SPTBN1 ARHGEF2 TCAP SORBS3 RHOB ROCK2 ARRB1 SYNPO SORBS1 ROCK1 VASP MYO1B COTL1 C9orf72 ACTR3 CAPZA2 WASF3 PLEK DSTN RUFY3 ADD1 ACTR2 LMOD3 HCK MTPN SRF NCKAP1L ARHGAP17 KANK1 MYO1C FAM107A TMOD1 WASF2 SYNPO2 RHOBTB2 RAC2 ARHGEF10 RHOG RHOJ PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 CAP1 PPM1F ESPNL SNX9 RHOQ	down	**
GO_ENDOCYTIC_VESICLE	0.0016549	0.0313466	0.4550599	-0.2613028	-1.456584	242	FFAR4 RAB11FIP1 MCOLN1 SCIMP HVCN1 WNT4 RAPGEF2 CAV1 HEATR5B CDC42EP2 CDC42 MARCO NCF2 CD9 LAMP1 SLC11A1 SCARF1 CD36 HBEGF RILP RAP1A PICALM FZD4 WNT3A RAB14 MSR1 RAB12 MPEG1 NOSTRIN VIM ATP6V0D2 SFTPD EPS15 HLA-DQA1 ANXA3 LMBRD1 TBC1D5 SNX3 MYO1C VAMP3 INPP5B SNAP23 APPL1 RAB8B RAB31 SFTPB RAC2 ATP6V0B RAPGEF1 STX7 RAB8A GRIA1 UNC13B UVRAG ATP6V0D1 UBB CD74 STXBP3 SFTPC PIK3C3 ATP6V0C STX12 SYT11 EPN2 ARRB2 RAB5A HSP90AA1 PTCH1	down	*
GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION	0.0000055	0.0003853	0.6105269	-0.2441374	-1.452940	545	SLC6A4 TNR SMAD6 DAB1 SEMA6B SEMA3G SEMA6A EREG ACVRL1 SOSTDC1 EDNRB DENND5A TAL1 KLF13 PPARG TBX3 GATA2 IL1B WNT4 RAPGEF2 BMP2 INSIG1 BDNF DDX6 CAV1 CORO1C CTDSP1 FGF10 MIR27B NFATC3 TRIB1 LILRB3 RHOA SEMA6D ANXA1 MIR146A FBXO7 ASAP1 SEMA3B FOXA2 ABCG1 PAQR3 HLX ADIPOR1 EIF4E GATA3 PPP3CA RB1 NFE2L2 SFRP1 WNT3A ZEB1 ARHGEF2 HNRNPU ZNF365 NODAL LRP4 SNAI1 NRARP FOXO1 PTPRO TRIM46 DAAM2 RUNX1T1 REST ID3 ZADH2 ARNTL SOCS5 CCL3 VIM HOPX ID2 TLR4 LBH SMAD7 INHBA TBX5 UBASH3B PAFAH1B1 RUFY3 HES1 AKIRIN1 KREMEN1 TGFB2 GNRH1 SRGAP2C KANK1 MYLIP RBPJ WNT9A ID4 CNTF PPP2CA AREG IL6 YBX1 MED28 PSEN1 NOTCH1 LIMD1 GABPA CUL4A CTSZ CNTN4 BAG5 SKIL IFRD1 PIK3R1 LSM1 RC3H1 RTN4R TRAK2 FSTL3 TBX21	down	***
GO_CYTOKINE_SECRETION	0.0021714	0.0371705	0.4317077	-0.2764101	-1.452630	181	FFAR4 NLRC4 IL17RB IL1A FCN1 IL1B LPL IL1RL1 GAS6 FGR CD36 ANXA1 MIR146A CARD16 FOXP1 GATA3 RGCC SPTBN1 CRTAM SRGN CD58 IL10 CASP1 CLECL1 CCL3 CADM1 TLR4 MIR24-2 CLEC9A RBPJ CD160 NOTCH1 CARD8 IFNGR1 PTGER4 CCR7 OSM CD34 MBP CHIA SERPINB1 LRRC32 ORM2 SYT11 RIPK2 NLRP3 HAVCR2 TLR10 MCOLN2 AIM2	down	*
GO_HEART_MORPHOGENESIS	0.0013907	0.0275668	0.4550599	-0.2661615	-1.450290	211	SMAD6 RBP4 TMEM100 ACVRL1 FOXF1 SOX18 TEK DLC1 CCM2L TBX3 BMP2 ENG FOLR1 SOX17 CITED2 BMPR2 S1PR1 TGFBR3 TGFBR2 HEG1 TBX2 GATA3 WNT3A TCAP FOXC2 NODAL ZMIZ1 SNAI1 TNNC1 GAA CLDN5 SEC24B ID2 SMAD7 ZMPSTE24 TBX5 DCHS1 HES1 MIR17HG TGFB2 SRF RBPJ PSEN1 JUN NOTCH1	down	*
GO_CELL_SURFACE	0.0000018	0.0001543	0.6435518	-0.2401427	-1.448823	669	TNR SIRPB1 SIGLEC11 AJAP1 RAMP3 ACVRL1 IL17RB FCN1 TEK ACE PECAM1 ADTRP GPIHBP1 CD55 SFRP4 SPN DCSTAMP WNT4 P2RY1 EMP2 CLDND1 BTNL9 RAMP2 THBD BMP2 TRPV2 CDH5 GPC5 ENG PCSK9 FOLR1 LPL CD44 CCRL2 FCER1A CLEC12B CDH13 BMPR2 ADCYAP1R1 C5AR1 S1PR1 FGF10 TGFBR3 MSLN IL1RL1 CD1C CD9 DSCAML1 LAMP1 CD22 TGFBR2 SCN5A ABCB1 CD8A HEG1 CD36 ANXA1 CD5 HBEGF ADA CD33 ARSB ADAM17 LIFR ABCG2 CLEC7A ITGA5 CLEC14A PICALM ANXA5 FZD4 ABCG1 ANPEP SLC7A11 MS4A1 SIRPA TMEM123 ISLR2 TNS1 CD93 SFRP1 WNT3A HNRNPU TFRC PDGFA KRT4 CD58 LRP4 GLDN SLC46A2 MSLNL AOC3 PLAUR THBS1 ADAMTS9 MPL CLIC4 ABCC4 ERP44 ITGAX PTPRC AQP4 SELL SELP AXL JAM2 TLR4 CD53 FCER1G CLEC9A KLRD1 VAMP5 IL7R BACE1 PROCR NRROS KCNA5 CD8B VAMP3 CD80 AREG PSEN1 IL2RB SLCO2B1 HCST NOTCH1 CTSZ TYROBP DUOX1 FERMT2 CCR7 ACKR3 CD83 CLEC17A RTN4R GRIA1 TNFRSF9 TNFRSF10B TIGIT MCAM CD34 CD151 SLC3A2 MBP CD74 CR1 MME CCR4 SORT1 TIMP2 TGFB1 TMX3 CD1D CD6 VAMP4 TSPAN14 LRRC32 KCNN2 CD86 PDCD1 GLRA1 LGALS3 KLRC4-KLRK1 IGHV3-23 CCR1 FCGRT SCARA5 NPTN ADAMTS15	down	***
GO_CATALYTIC_ACTIVITY_ACTING_ON_RNA	0.0018119	0.0332048	0.4550599	0.3022660	1.446075	310	DDX12P SLFN13 DROSHA PRIM2 PIF1 METTL1 DGCR8 RAD54B AARS2 POLR3A EXO1 RPAP1 QTRT1 LARS2 NSUN2 TRPT1 EMG1 TARS2 ANG SARS2 POLR3C TRMT61B FBL TRMT2A BRIP1 TRIT1 DDX56 DDX51 HARS2 EXOSC2 DTD1 DIS3L2 TYW1 POLR3K CMTR1 DHX37 DHX33 FEN1 POLR1C METTL3 NOP2 RTCB RNASEH2A DHX34 POLR2H PARS2 MOV10 CNOT2 DHX40 PUS1 AARSD1 USB1 NUDT16 TSEN54 SND1 ELAC2 YARS2 IARS2 PPP1R8 DUS1L POP7 POLR2J FANCM METTL2B NSUN6 DHX8 NOB1 DDX23 POLR2J3 EXOSC5 DUS4L POLR2I POLR3E RNASET2 IGHMBP2 RPP38 DDX55 DUS2 FARSA PRPF18 RRNAD1 PRIM1 DCPS DDX54 POLR3B WDR4 FARSB TARBP1 SNRNP200 POLR1B POLR1A EARS2 DDX52 POP4 APEX1 CDKAL1 DTD2 AZGP1 DDX41 FTSJ3 TFB1M DHX57 POLRMT	up	*
GO_RESPONSE_TO_PEPTIDE	0.0000906	0.0035593	0.5384341	-0.2476404	-1.445134	412	EREG RAMP3 LPIN2 TEK EDNRB PPARG HHEX CPEB2 IL1B LHCGR CAT ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL EGR2 INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A TGFBR3 CD36 ANXA1 MIR146A ATP2B1 BTG2 ANXA5 KLF10 CAV2 ADIPOR1 NR4A1 ADRB2 NFE2L2 NDEL1 CRK ARHGEF2 EPM2AIP1 ATP6V1H ATP6V1B2 FOXC2 IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 KLF4 ROCK1 KLF11 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 VIM ATP6V0D2 TLR4 PIK3C2A GNAI2 TBC1D4 BACE1 GNRH1 BTG1 SLC25A33 PDK4 KANK1 MYO1C ADCY2 AREG PSEN1 SOCS3 APPL1 RAB8B STAT4 NOTCH1 RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ KLF2 CACYBP FOXO3 SRSF6 IRF5 SORT1 STXBP3 SRSF4 FPR2 GNAI1 ATP6V1A IRS2 ATP6V0C	down	**
GO_ERK1_AND_ERK2_CASCADE	0.0024463	0.0403154	0.4317077	-0.2579576	-1.441511	243	FFAR4 HCRTR1 SEMA6A RAMP3 TEK SCIMP GLIPR2 IL1B P2RY1 RAPGEF2 BMPER BMP2 CD44 CCL3L1 C5AR1 HMGCR APIP FGF10 MIR27B MARCO GAS6 CD36 RAP1A RANBP9 SIRPA SPRY2 PDGFA NODAL ARRB1 DUSP3 CCL22 NPNT KLF4 PDE8A CCL3 PTPRC ATF3 CCL4 TLR4 MIR24-2 XCL2 DUSP1 GNAI2 DNAJC27 JUN NOTCH1 ADRA1A RAPGEF1 PTGER4 CCR7 ACKR3 GPR183 FGFR4 SPRY4 RRAS CD74 TGFB1 FPR2 MIR23A NLRP6 NQO2 CCR1 NPTN CCL20 ICAM1 FGF2 ARRB2 TIAM1 RIPK2 HAVCR2 EPHA2	down	*
GO_SECRETORY_VESICLE	0.0000007	0.0000638	0.6594444	-0.2364793	-1.434903	744	SIRPB1 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 IL1B MNDA CLEC3B LTA4H SNX10 CAT RAB44 CLEC12A IZUMO1 RAB3C PTPRB OSCAR BDNF MMRN1 CD44 CTSW CAV1 BAIAP2 CHIT1 CYB5R3 VAMP2 PAFAH1B2 TBXA2R C5AR1 YPEL5 STX11 CDC42 MANBA NCF2 VAPA CD9 FUCA1 GAS6 LAMP1 SLC11A1 LILRB3 FGR RHOA CD36 SLC44A2 DNAJC3 MAN2B1 MCTP1 CD33 ARSB ASAH1 RAP1A GM2A PICALM ANPEP CAV2 PTX3 STOM LAIR1 SIRPA NDEL1 CD93 GRN LAMTOR3 SRGN PDGFA RAB14 CD58 CST3 FABP5 CFD RAB12 EXOC3L1 PPT1 SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 THBS1 STX3 ATP6V1D MYRIP FAM49B ABCC4 SPAG9 CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL SELP HPSE ARC ARHGAP9 CD53 FCER1G GCA WFS1 DEGS1 ANXA3 BACE1 CMTM6 COPS4 VWF ACTR2 TGFB2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP VAMP3 CTSS PSEN1 PHACTR2 NKD2 EBAG9 SNAP23 RAB8B CYB5R1 CAPN11 VAT1 NOTCH1 RAB31 SFTPB HK3 CTSZ TYROBP HSPA1B ATP11A RHOG STX7 SKIL ENPP4 GLIPR1 GMFG RAB8A SERPINB6 GRIA1 UNC13B CAP1 PRKACA TCP1 FSTL3 CLN3 WDR7 ATP6V0D1 CTTNBP2 PSMD12 ALDH3B1 BIN2 CR1 SYPL2 MME CPA3 TIMP2 STXBP3 SIGLEC14 TGFB1 TMX3 DOK3 SFTPC SERPINB1 VAMP4 FPR2 MTMR2 CDC37L1 TMEM230 TSPAN14 DYNC1LI1 ATP6V0C SLIRP GPR84 APLP2 LGALS3 ORM2 BRI3 STX12 ACTN2 PLEKHO2 CSNK2A2 ADAM10 PDE4B IST1 SYT11 COMMD9 TCTEX1D4 UNC13D	down	***
GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	0.0000686	0.0028958	0.5384341	-0.2420491	-1.434741	501	NLRC4 EREG CD300LF IL17RB SASH1 SWAP70 FCN1 SCIMP SIGLEC16 PGC IL1B FABP4 MNDA THBD FYN LPL LY86 CAV1 CDH13 MYD88 BMPR2 C5AR1 CLEC10A RBM14 S1PR1 FGF10 MARCO IL1RL1 GAS6 OTUD4 PSMD5 LAMP1 SCARF1 RFTN1 IL23A PDE2A CD36 MIR146A PLA2G7 ADAM17 CLEC7A TNIP3 HSPB1 RNF125 IFNK TRAF6 NDEL1 GRN CRTAM UBE2D3 BIRC2 SLC46A2 THBS1 CEBPA STX3 LY96 UBQLN1 CCL3 NFKB1 CADM1 IRAK2 CCL4 TLR4 PTGER3 SFTPD XCL2 FCER1G OXSR1 AKIRIN1 HCK NCKAP1L IL17D CNTF IL6 MUC3A CD160 CTSS APPL1 SEC14L1 PSMA1 ETS1 RAC2 HSPA1B PTGER4 CCR7 DAPK2 PRKCE OSM MALT1 UNC13B PRKACA SUCNR1 PPM1F PLCG2 UBB PELI1 PSMD12 ICAM2 CD74 PIK3AP1 SMPDL3B CCR4 TGFB1 AP1G1 CD1D CD6 FPR2 NLRP6 PIK3C3 CD81 KLRC4-KLRK1 CCR1 ADAM10 CCR6 FGF2 IL18 IL18RAP ARRB2 RTN4 TIAM1 CXCR4 TAB2 RIPK2 UBE2D1 HAVCR2 PSME4 CREBBP ICAM3 TLR10 SIN3A NFKBIA CTSC EDN1 PAK2 KLRK1 AIM2 FGFR1 ITCH LDLR PSMD6 PSMD9 SFPQ IL16 PUM1	down	**
GO_CELL_JUNCTION_ASSEMBLY	0.0018893	0.0340677	0.4550599	-0.2636272	-1.434284	213	LIMS2 ACVRL1 TEK ACE DLC1 PECAM1 IL1B WNT4 RAPGEF2 RAMP2 CDH5 CAV1 CORO1C CDH13 ESAM CDC42 CD9 EPB41L3 HEG1 RHOA APOD RAP1A ITGA5 JAM3 TNS1 SFRP1 GPBAR1 ROCK2 SNAI1 DUSP3 SORBS1 PTPRO LIMS1 ROCK1 VASP TJP1 THBS1 CLDN5 SMAD7 PEAK1 SRF MYO1C FAM107A PDCD6IP MAP4K4 RAPGEF1 FERMT2 PRKACA PPM1F CD151 GJA4 WNT11 FLNC EPHA3 PARD6A STRN TESK2 CNTNAP1 CLASP2 ACTN2 MACF1	down	*
GO_RESPONSE_TO_INSULIN	0.0015974	0.0304287	0.4550599	-0.2620034	-1.432034	219	LPIN2 PPARG CPEB2 IL1B CAT PTPRE PID1 KL PCSK9 LPL EGR2 INPP5K BAIAP2 VAMP2 ATP2B1 CAV2 ADIPOR1 NDEL1 EPM2AIP1 ATP6V1H ATP6V1B2 FOXC2 IL10 RAB12 FOXO1 SRSF5 SORBS1 ATP6V1D PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 SLC25A33 PDK4 KANK1 MYO1C SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 RAB8A ATP6V0D1 RHOQ FOXO3 SRSF6 SORT1 STXBP3 SRSF4 ATP6V1A IRS2 ATP6V0C CRY1 KAT2B	down	*
GO_SEXUAL_REPRODUCTION	0.0004571	0.0126912	0.4984931	0.2878725	1.427646	538	TSPAN8 SYT8 TRIP13 TP63 SPATA24 SPATA25 MYCBPAP FOXA3 PPP1R1B RUVBL1 PMFBP1 SPINK13 CCNB1 WFDC2 DPY19L2P1 CLGN GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 NOX5 SPINK1 CIB1 TDRKH MCM8 SRPK1 CCT2 RSPH1 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A CCT5 AURKA REC8 ODF2 SYCP2 POC1A IL12B DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 OAZ3 CGB7 HSF2BP MST1R OXTR BRIP1 GNPDA1 SPAG8 PTGDR2 CCDC136 ALDOA MEA1 ASF1B LRGUK CDK1 MERTK PICK1 CCT3 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 MTOR CTSV MNS1 ADAM28 IQCG MORN2 UBE2Q1 PCSK4 GAS2 TSSK3 SPAG1 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 THRB TYRO3 CCT7 NR6A1 KDM3A PTN MEI1 ROPN1B AAAS BCL2L1 CATSPER2 BAD DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 PKDREJ GGT5 ETV6 PHC2 PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2	up	*
GO_CELL_SUBSTRATE_ADHESION	0.0008380	0.0195671	0.4772708	-0.2488825	-1.426967	308	SMAD6 LIMS2 AJAP1 LYPD5 ACVRL1 FOXF1 TEK DLC1 PECAM1 ATXN3 WNT4 LYVE1 EMP2 CD44 RADIL CORO1C MYADM CDH13 CDC42 MSLN NEDD9 GAS6 RHOA APOD CD36 ITGA5 PARVG FZD4 JAM3 CRK SFRP1 SORBS3 ROCK2 SNED1 TIMM10B DUSP3 SORBS1 NPNT PTPRO LIMS1 BST1 MSLNL ROCK1 PARVB THBS1 ADAMTS9 LAMC3 AXL HPSE PEAK1 VWF SRF NINJ1 TECTA KANK1 FAM107A VAMP3 UTRN LAMB2 NDNF NOTCH1 RAC2 MAP4K4 FERMT2 CCR7 PIK3R1 PRKCE HSD17B12 ITGA11 PPM1F CD34 SIGLEC1	down	*
GO_RIBONUCLEOTIDE_BINDING	0.0000001	0.0000075	0.7195128	0.2767223	1.426422	1571	KIF1A ATP10B CPS1 PDE11A KIF12 STYK1 TRIP13 HKDC1 ABCA13 DDX11 ENTPD2 ABCC2 HELLS EPHB3 KIF20A CNGA1 DDX12P RUVBL1 AK4 DNAH2 CHEK2 BUB1B SLFN13 MYO3B PPIP5K1 NEK2 XYLB FRK POLQ UBE2T PBK KIF18B TTF2 GUCY2C PIF1 NMNAT3 IP6K3 STK36 TUBB2B TTK CDK4 BRSK1 SLC27A2 KIF14 UBE2Z RHOV ABCA12 GMPS STK31 FLAD1 PLK1 IFT27 AURKB ACAD9 ALDH18A1 PAK6 CDC6 WNK2 TRIB3 FIGNL1 MCM4 PRKCA RAB36 MCM2 RAD54B DNAH3 PMS2 NWD1 XRCC2 ORC1 AACS CCT6A MCM8 PIP4K2C LIG3 MAP2K6 SGK2 SRPK1 KIF27 INSRR EPHB1 P2RX2 DNAH14 MPPED2 CCT2 AGK AK8 SCG5 NME1 IKBKE AARS2 TTLL4 RUVBL2 MELK DYRK1B KIF23 MKI67 CUL9 SLFN5 RND2 HLTF KIF15 PCCB HS3ST5 MAP3K13 KIF3B BUB1 TOP2A CCT5 AURKA MYO10 HHAT ATR RAB19 GTPBP3 LARS2 SMARCAL1 KIF2C MCM7 IFI44L COASY ABCC5 TTLL12 PRKDC RHOBTB3 HELB RAD54L ERAL1 PKM SBK1 EIF2AK1 PHKG2 KIF11 PASK MCM3 PEX6 MCCC2 TARS2 CHD6 EGFR DNAH8 LIG1 SARS2 RIPK4 MORC2 ABCB6 CHEK1 NEK11 ASS1 ACSF2 KIF3C EPHA10 RAB13 PFKP ABCB9 HSP90AB2P MST1R KCNJ11 KHK AKT2 CNGB1 PKMYT1 DNAH11 BRIP1 DDR1 EEFSEC CAD BLM MTG1 PPP5C ATAD3C ARL16 ERCC2 TRPV4 MYO1A TRIT1 RECQL5 DYRK2 DDX56 MARK1 TNIK IKBKB DCLK1 TTBK1 CBWD6 FASTK NSF DDX51 HARS2 PAK1 LRGUK CDK1 CDK12 DNAH6 EPHA1 KIF5A UCK2 GBP3 MERTK STK32A CCT3 ATP2A1 NUDT2 TTLL9 TNK2 NAV2 TYW1 DHX37 TRAP1 ABCC11 SYN3 MAP3K10 KIF19 DNA2 ACTR3C KIF2A DHX33 ACSBG2 KIF7 ITPKA KSR2 PDK1 NEK5 ACTR3B MYO5B RAB6B AK7 ATAD3A DNAH5 PRKAA2 ABCA4 UCKL1 PSMC4 RTCB RECQL4 MAST1 ACVR1B GBP5 STK11 TEP1 GAL3ST4 ULK1 EFTUD2 DHX34 HSPA4L NMNAT2 MYO19 ACBD6 PARS2 MOV10 ANKK1 ILF2 ARFRP1 RHOC CDK3 TUBG1 ATP7B RABL2A DCAKD NEK10 NADK2 SPG7 DNAH7 DHX40 GALK2 TRMU MTOR GSS DNAJA3 ATP9A AARSD1 LONP1 DHODH TRIO TUBB2A TUBA3D KIF22 MAPK13 RAD51D EPHB2 ARF5 ACBD4 DNM1 UBE2Q1 TK1 DTYMK TUBA8 CHTF18 GBP6 CNGA4 SCN8A URGCP KIF21A CSNK1G1 LMTK2 SLC22A5 HSP90B2P NUDT16 MAPK10 TSSK3 SPAG1 KIF20B DAP3 NDUFA13 ASNS GFM2 GK5 CHD5 CDK13 TTLL10 TWF1 ACSL6 GNAZ TYRO3 ATAD5 RAB24 MAT1A ATP13A1 NADSYN1 CCT7 CDC7 IP6K2 YARS2 RAD50 ABCC10 TNK1 EP400 ACBD5 PFAS LSG1 UBE2O ABCC9 ENTPD8 DGKA IARS2 ERBB3 TUBG2 POPDC2 TTLL3 ACLY ENTPD3 ABCC3 ABCA7 FANCM MCM6 MYO5C CKMT2 WRNIP1 DYNC1LI2 KIF21B CDC42BPG SRPK2 DHX8 MCM5 NMNAT1 RAB15 ACOT11 ZRANB3 DDX23 DYNC2H1 NEK4 LANCL2 SCYL3 RAB3D ADCK1 PIP5K1A MYH7B PFKFB4 RTKN LRRK1 TTLL6 IGHMBP2 RHOBTB1 MYH3 MAB21L1 RAP2B MUSK ABCD4 PALM3 PRKD2 STK39 PI4KA STK35 DDX55 ATAD2 TSR1 DUS2 GTPBP10 RAB34 GNAL FARSA NDUFV1 MYH13 ROS1 MSH4 PMS1 ATP6AP1 MSH2 MAP3K14 ME1 ADCY1 SMARCA4 ULK4 STK38 DDX54 ABCF3 RTEL1 CDC42BPA RFC5 CSNK1G2 NUGGC GBP1 NME4 PAK4 GTPBP2 ICK ABCF2 ACSF3 NUBP2 DNAH1 HK2 TUBA4B BMS1 RAD51 HLCS ARL17B FARSB STK25 MAP3K9 PFKM ARHGAP5 NOS1 MARK4 GBP2 SNRNP200 NME7 CHD3 CDK5 GNA14 POMK RHOT2 ERBB2 NUBPL SMC2 GNA12 RAB43 PNKP ADCY6 CENPE EIF4G1 RHOD GNE SRCAP EARS2 MYO15A DDX52 HSPA7 GLYCTK NDOR1 MTHFD1 TP53 RAB25 SRPRB CBWD1 TSSK4 SEPHS1 PAICS TIMM44 EPHB4 UBE2C GPN1 NPR2 RIPK3 ADCK2 OAS3 TUBA1C PI4KB NAT10 DNM1L RABL6 TK2 TTLL5 BRSK2 KIF24 MOK ALPK1 DDX41 MTG2 MAP3K19 MAP2K2 ACSL5 NLRC5 ERCC3 PRKAG1 ROR2 SLFNL1	up	***
GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS	0.0000002	0.0000181	0.6901325	-0.2300957	-1.424610	908	SIRPB1 RBP4 NLRC4 EREG CD300LF FOXF1 HMOX1 SWAP70 FCN1 CD101 GCSAML SCIMP TAL1 CD55 FCN3 GATA2 SPN PGC IL1B MNDA DCSTAMP LPXN BTNL9 FYN HCAR2 CAV1 BAIAP2 PRAM1 MYD88 ELF2 PLEKHA1 C5AR1 CLEC10A RBM14 FGF10 ELMO1 CDC42 MARCO IL1RL1 CD1C GAS6 OTUD4 PSMD5 LAMP1 CD22 SLC11A1 TGFBR2 TRIB1 RFTN1 IL23A FGR RHOA CD36 ANXA1 MIR146A PLA2G7 SPG21 CLCF1 IGKV2-28 CD5 ADA ADAM17 RAP1A CLEC7A MASP1 TNIP3 MAP3K8 RNF125 KLF10 FOXP1 HLX PAG1 MS4A1 IFNK GATA3 SIRPA RB1 RGCC IL18R1 TRAF6 CRK CRTAM WNT3A PDE4D UBE2D3 TFRC ZMIZ1 EVI2B IL10 CFD DUSP3 BIRC2 BST1 SLC46A2 PTAFR THBS1 CEBPA CLECL1 SOCS5 MPL LY96 FAM49B UBQLN1 CCL3 NFKB1 CDKN1A CADM1 PTPRC IRAK2 SELP AXL ID2 CCL4 JAM2 TLR4 IGFBP2 ACTR3 SFTPD XCL2 FCER1G INHBA OXSR1 IL7R HLA-DQA1 HES1 C4BPB AKIRIN1 ACTR2 TGFB2 HCK NCKAP1L IGLV2-11 MYO1C CD80 ELF1 IL6 WASF2 MUC3A CD160 CTSS PSEN1 APPL1 AQP3 SEC14L1 C1QA JUN PSMA1 ETS1 RAC2 TYROBP HSPA1B RAPGEF1 CCR7 STX7 ATXN1L DAPK2 PIK3R1 CD83 PRKCE GRB2 GPR183 CREB1 MALT1 RC3H1 PRKACA DOCK8 AP3B1 TBX21 IGKV3-20 PLCG2 FOS UBB PELI1 TNFSF13 PSMD12 RUNX3 FOXO3 ICAM2 TREX1 CD74 CR1 PIK3AP1 SMPDL3B TGFB1 VAV3 AP1G1 CD1D ZBTB1 CD6 TEC FPR2 NLRP6 MIA3 PIK3C3 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 BAG6 CCR1 FCGRT N4BP2L2 ADAM10 PDE4B IGKV1D-39 CCL20 UNC13D CCR6 ICAM1 TRAC IL18 IL18RAP LAT ARPC2 ARRB2 RTN4 HSP90AA1 TAB2 RIPK2 NLRP3 UBE2D1 ACTB HAVCR2 PSME4 CREBBP ICAM3 CD19 TLR10 SIN3A NFKBIA CTSC CD1E EDN1 CD3G ARPC5 PAK2 KLRK1 TNFSF9 AIM2 THEMIS2 ITCH PSMD6 PSMD9 SFPQ	down	***
GO_REGULATION_OF_SYSTEM_PROCESS	0.0000582	0.0025662	0.5573322	-0.2444530	-1.423796	424	TNR RAB11FIP1 EPAS1 HSPB7 TMEM100 SCN4A ACE EDNRB IL1B EMP2 FIG4 TRPC3 SHANK3 HCAR2 INPP5K CAV1 BAIAP2 CALCRL ADRA1D BMPR2 TBXA2R FXYD2 FGF10 MEF2A GAS6 SCN5A RHOA TBX2 ATP2B1 HBEGF ADA CACNA2D2 LMNA KCNK3 PBX3 GLS ADRB1 DES PPP3CA ADRB2 PDE4D SGCA SETD3 TMEM38B CNN1 IL10 FABP5 ROCK2 TNNC1 FOXO1 KCNMA1 NPNT PTPRO TACR2 PTAFR KLF4 ROCK1 GAA CDK9 CCL3 SSH1 PER2 ITGAX PTGER3 WASF3 SMAD7 ZMPSTE24 INHBA FXYD7 GNAI2 CALM2 MIR17HG TGFB2 MTPN SRF KCNA5 SLC8A1 SCN4B SGK1 RAB8B UTRN NOTCH1 HRH1 ADRA1A PDE5A GSTO1 PTGER2 NPR1 UNC13B PRKACA HOMER1 CST7 CELF2 LMCD1 CALM1 FOXO3 TSHZ3	down	**
GO_LYMPHOCYTE_ACTIVATION	0.0000117	0.0007154	0.5933255	-0.2363248	-1.422709	573	SIRPB1 SWAP70 CD55 HHEX GAPT SPN IL1B MNDA WNT4 LYL1 FYN CD44 CAV1 FGF10 PRKAR1A CDC42 CD1C GAS6 LAMP1 CD22 SLC11A1 TGFBR2 IL23A CD8A FGR RHOA ANXA1 CLCF1 FBXO7 CD5 ADA ADAM17 CLEC7A MAP3K8 FOXP1 KLF6 HLX PAG1 MS4A1 LCP1 IFNK GATA3 PPP3CA SIRPA IL18R1 TRAF6 SFRP1 WNT3A ZEB1 SPI1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 BST1 SLC46A2 FUT7 CLECL1 SOCS5 MPL FAM49B CDKN1A PTPRC AXL ID2 TLR4 IGFBP2 SFTPD PRF1 FCER1G SMAD7 INHBA IL7R CYP26B1 HES1 MIR17HG GNRH1 SRF NCKAP1L CD8B RBPJ CD80 IL6 PKNOX1 CD160 PSEN1 PDE5A RAC2 TYROBP PTGER4 CCR7 SP3 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 DOCK8 AP3B1 CD7 TBX21 ZNF683 TIGIT PLCG2 CD151 PELI1 AZI2 TNFSF13 RUNX3 TREX1 CD74 CR1 TGFB1 VAV3 AP1G1 CD1D ZBTB1 JMJD6 CD6 LRRC32 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 BAG6 MFNG GPR18 UNC13D CCR6 ICAM1 IL18 LAT FKBP1A NBN SEMA4A RIPK2 NLRP3 CCR9 HAVCR2 CD19 ADORA2A KIT DOCK10 CD3G PAK2 KLRK1 DNAJB9 TNFSF9 SAMSN1 RORA CCND3	down	***
GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION	0.0030149	0.0472233	0.4317077	-0.2705167	-1.421913	177	CD55 HHEX SPN IL1B MNDA FGF10 PRKAR1A CD22 TGFBR2 IL23A ANXA1 CLCF1 ADA TRAF6 WNT3A MAPK8IP1 TFRC IL10 BST1 CLECL1 MPL CDKN1A PTPRC TLR4 IGFBP2 SFTPD HES1 GNRH1 NCKAP1L CD80 IL6 PDE5A RAC2 TYROBP GPR183 RC3H1 PELI1 CD74 VAV3 CD1D CD6 LRRC32 CD86 IRS2 CD81 LGALS3	down	*
GO_MUSCLE_CELL_DIFFERENTIATION	0.0006268	0.0159045	0.4772708	-0.2486670	-1.420081	288	EREG FOXF1 EDNRB TBX3 WNT4 RAMP2 BMP2 SIK1 ENG BDNF TMOD3 QKI FGF10 PRKAR1A MEF2A CDC42 CD9 NFATC3 TBX2 MYOZ1 CACNA2D2 LMNA CSRP1 TMEM204 CAV2 PPP3CA RBM4 RB1 WNT3A ZEB1 HNRNPU TCAP SETD3 NPNT BNIP2 CDK9 SPAG9 MIR24-2 CD53 ZMPSTE24 TBX5 CYP26B1 MYH11 HES1 TANC1 LMOD3 PIAS1 MTPN SRF RBPJ SLC8A1 TMOD1 YBX1 MED28 NOTCH1 ADRA1A EPC1 IFRD1 HOMER1 CACYBP EHD2 FLNC SYPL2 SORT1 TGFB1 EHD1 MIR23A CD81 SOD2 MYOCD GATA6 ACTN2 RGS2 RXRA PDLIM5 WDR1 LMOD1 ARRB2 TMOD2 KIT EDN1 SKI SYNPO2L RORA NRG1	down	*
GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION	0.0030928	0.0477205	0.4317077	-0.2604201	-1.412413	209	ANGPT4 EREG ACE TAL1 PECAM1 BDNF FYN CD44 CAV1 FGF10 NEDD9 GAS6 CBL IL23A CD36 MIR146A SH2B3 CLCF1 HBEGF ADAM17 ITGA5 SFRP1 WNT3A ARHGEF2 PDGFA LRP4 BST1 SOCS5 PTPRC EPGN HES1 IL24 CD80 CNTF PPP2CA AREG IL6 PSEN1 SOCS3 SH3BP5 ADRA1A PRKCE OSM GPRC5A CD74 TGFB1 TEC CNOT7 CD81 ICAM1 IL18 ARRB2 EPHA4 RIPK2 KIT PAK2 SAMSN1 NRG1 IQGAP1 EHD4 BANK1 CSF2 ABI1 GREM1 GHR	down	*
GO_ORGANELLE_INNER_MEMBRANE	0.0013414	0.0268644	0.4550599	0.2880745	1.410526	420	CPS1 BDH1 COA1 CHCHD6 SLC25A21 THEM4 MRPL46 NDUFS6 ACAD9 ALDH18A1 SFXN1 NNT TYMS COX6B2 SHMT2 P2RX2 MRPS35 COQ3 COX11 AGK UQCC1 TAMM41 FAM169A NDUFB8 SDHA DPY19L2P2 MRPL15 DPY19L1 CBX3 NDUFS2 TMEM177 GCAT ERAL1 MRPL3 MRPL27 LMNB1 SLC25A39 TIMM50 MRPS11 FDXR MRPS30 MTG1 PHB SLC25A10 UQCR11 COQ9 MRPL36 MRPL37 GOT2 SUN1 TRAP1 L2HGDH MRPS2 SLC25A13 MRPL17 MRPS12 TMEM120B ATAD3A UQCC2 CHCHD3 UQCRFS1 NDUFA11 SPG7 COA3 FOXRED1 LMNB2 SLC25A18 MRPS34 DHODH MRPL11 MRPL52 COX7C PPOX MRPL4 DAP3 DNAJC11 NDUFA13 COX10 TIMM13 STOML2 CHCHD1 SIRT4 MRPS23 BCL2L1 MRPL24 MRPS33 CKMT2 MRPL28 MRPL41 ROMO1 SIRT5 DPY19L2 MRPL53 PRODH NDUFS7 MRPL51 SPAG4 NDUFV1 MRPL14 SCO2 MRPS25 MRPL55 NME4 UQCRC1 COX5B SLC25A29 MCU MRPL9 MRPL21 MICU1 NDUFA8 NDUFS8 CPOX AURKAIP1 UQCRQ TIMM44 LEMD2 MRPS27 SIGMAR1 SFXN4 MRPL20 MRPL48 NDUFB7 COX6B1 MRPS26 IMMP2L TMEM201 CYP11A1 MTG2 NDUFAF6 MRPS16 UCP3 SPHK2 DPY19L3 MRPL12 CRAT PARL MRPL43 OPA1 RSAD2 MRPL2 TOMM40 TIMM10 COQ5 MRPS6 NDUFB2 SMAD3 LRPPRC COX15 TIMM9 COX6A1 SLC25A35 COQ4 NDUFA4L2 COX6C ABCB8 NDUFA9 SDHC SLC27A1 WDR93 MRPS7 MRPL35 SMAD1 MRPL13 GATM MRPL33 NDUFA10 PET100 LEMD3 COX16 SRC PSEN2 NDUFB10 TIMM23 IMMP1L NDUFS4 ERN1 CYP2E1 PLA2G4B	up	*
GO_CELL_CYCLE	0.0000004	0.0000466	0.6749629	0.2732469	1.407453	1523	HMGA2 CCNO PKHD1 MCIDAS TRIP13 DDX11 FOXM1 CEP72 SPICE1 BRINP1 HELLS KIF20A MDM1 DDX12P HJURP STAG3L2 CUZD1 RUVBL1 CDC45 TICRR MCM10 FANCI CHEK2 BUB1B NEK2 TRNP1 CCNB1 SOX2 CENPF TIMELESS PAGR1 PDCD2L STOX1 MND1 PBK KIF18B NDC80 PRIM2 TBRG4 BRCA1 PHGDH TUBB2B TTK GINS1 CDCA2 CDK4 SMPD3 RACGAP1 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN SLC26A8 POLE CNTD2 ASPM NABP2 STIL MSTO1 CEP70 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 E2F3 TFDP2 CCNB2 FIGNL1 RBBP8 UHRF1 MCM4 PRKCA CYP27B1 MCM2 RAD54B TYMS CDC25A MYBL2 PRC1 XRCC2 ORC1 NOX5 CCNF DTL CIB1 TDRKH MCM8 LIG3 MIS18A MAP2K6 ZFYVE19 NCAPD2 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 LMLN HAUS5 RANBP1 CEP250 WDR62 RSPH1 CASP2 MELK HMMR BTRC SMARCD3 EXO1 DLG1 NLE1 KIF23 CEP55 STAG3 CHAF1A FOXA1 MKI67 CUL9 BOD1 CUL7 KIF15 TP53BP1 FBXO43 KNTC1 RHNO1 KIF3B BUB1 FANCA LGMN MSX2 AUNIP TOP2A MAP10 GPER1 AURKA EME1 CBX3 REC8 ODF2 POLA2 SYCP2 ATR POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 E2F2 MSX1 CD2AP CENPW POC1A CLSPN CXCR5 IL12B RRM2 TTLL12 CDCA5 PRKDC WDHD1 FSD1 NSUN2 RAD54L TOM1L1 KIF11 FANCD2 GPSM2 MCM3 CHAF1B HORMAD1 CDC25C SOX4 TGM1 EGFR LIG1 EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 SOX11 MDM2 SPC24 AKT2 DSCC1 MGA PKMYT1 BRIP1 FBXL8 SPAG8 BLM PPP5C PML C2CD3 CNOT3 ERCC2 MNAT1 STXBP4 SPRY1 PARD3 SLC39A5 SKP2 RECQL5 PES1 PSRC1 PTPN3 INCENP KNSTRN CKS1B TTBK1 NCAPG2 AFAP1L2 CDKN2C NUSAP1 CBX5 KRT18 ANAPC5 ING4 CTDSP2 CDK1 CROCC CDK12 POLE2 CEP97 CENPJ RFWD3 BIRC5 KIAA0753 GMNN SUN1 DIS3L2 POC5 E2F1 NCAPG PSMB5 CCNJL TMEM8B DNA2 KIF2A STEAP3 ANAPC7 FEN1 SSX2IP EZH2 CNOT11 SPAG5 EGF TAF6 METTL3 RAB11FIP4 SAPCD2 TRAPPC12 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP STK11 IRF6 KPNB1 GIPC1 MYO19 ANKK1 CEP63 INTS7 CCNE1 CEP192 RHOC CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 MTOR NINL TACC3 MNS1 RAD9A LLGL2 TUBB2A PSME2 KIF22 HIRA MAPK13 RAD51D MTA3 TRIM37 FBXO4 TUBA8 CHTF18 MYBBP1A CENPQ AKAP8L URGCP ESCO2 GAS2 FZR1 PKP4 NUDT16 CGREF1 CLTA KIF20B LAMTOR2 LIN37 SMIM22 TRIM32 ASNS SGSM3 ANAPC1 SND1 CDK13 POLD1 PSMD2 JTB ATAD5 PPME1 SLX4 CABLES2 CDC7 RAD50 ANKRD31 CENPK PROX1 SASS6 KLHDC3 SH2B1 TADA3 STAG3L4 CENPV MEI1 CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B ROPN1B TUBG2 AAAS GBF1 EFHC1 ALKBH4 BCL2L1 RPA1 CHMP4C PELO WNT10B FANCM CDK5RAP2 MCM6 DNMT3A CHTF8 BLCAP THOC5 STAMBP MRPL41 CENPT PRMT1 CKAP2 SRPK2	up	***
GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY	0.0022986	0.0386939	0.4317077	-0.2589311	-1.405058	215	RASIP1 HHEX IL1B FABP4 INPP5K CAV1 CORO1C HMGCR PRKAR1A CBL TRIB1 HEG1 SH2B3 DNAJC3 FBXO7 FOXA2 LATS2 HSPB1 HIPK3 PAQR3 RB1 SFRP1 SPRY2 HNRNPU MAPK8IP1 ADARB1 ITPRIP DUSP3 CEBPA SOCS5 CDKN1A PTPRC MIR24-2 DUSP1 PPP2R5A GNAQ UBASH3B PKIG PPP2CA PSEN1 SOCS3 SH3BP5 DNAJA1 DUSP8 IPO7 GMFG GPRC5A PPM1F SPRY4 PKIA CHORDC1 SMCR8 DUSP5 IRS2 MYOCD RGS2 KAT2B DBNDD2 PP2D1 CDKN1C IPO5 ADORA2A PAK2 PTEN DUSP7	down	*
GO_AMIDE_BINDING	0.0018339	0.0335458	0.4550599	-0.2519072	-1.403700	260	HCRTR1 CD300LF RAMP3 COL25A1 EDNRB TRHDE PPARG RAMP2 FOLR1 GLTPD2 CALCRL ADCYAP1R1 MARCO CD1C HSPG2 CD36 SSTR1 PICALM ANXA5 FZD4 NMUR1 ANPEP PEX5L PPP3CA ADRB2 SLC19A1 CST3 KPNA5 MSR1 SCP2 ITM2B SLC7A8 BCHE TPP1 NPR3 TLR4 INHBA KPNA3 HLA-DQA1 BACE1 PTH1R TGFB2 PLEKHA3 C1QA APBB2 PIK3R1 NPR1 RTN4R GRIA1 GPR37L1 ECI2 CD74 PNPLA3 MME NUP153 GSAP CD1D FPR2 APBB1 PPP3R1 PPIG NQO2 ACADL PGGT1B PPID PCCA RXRA TIMM22 GLTP EPHA4 ALDH6A1 DLGAP3 IPO5 ACACB NUP98 SOAT1 KPNA4 NFKBIA CD1E GNMT	down	*
GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT	0.0021097	0.0362984	0.4317077	-0.2506353	-1.402831	258	SLC6A4 TNR DAB1 SEMA6B SEMA3G SEMA6A EDNRB DENND5A IL1B RAPGEF2 DDX6 CORO1C CTDSP1 RHOA SEMA6D MIR146A ASAP1 SEMA3B PAQR3 EIF4E PPP3CA WNT3A ARHGEF2 ZNF365 NODAL LRP4 PTPRO TRIM46 DAAM2 REST ID3 VIM ID2 PAFAH1B1 RUFY3 HES1 KREMEN1 GNRH1 SRGAP2C KANK1 MYLIP ID4 CNTF IL6 PSEN1 NOTCH1 CTSZ CNTN4 BAG5 IFRD1 LSM1 RTN4R TRAK2	down	*
GO_CELL_LEADING_EDGE	0.0015261	0.0297409	0.4550599	-0.2407996	-1.400911	345	AKAP5 ARHGAP31 SWAP70 DLC1 SCIMP FGD5 KCNA2 RDX CD44 CCDC88A INPP5K LDB2 CORO1C MYADM BAIAP2 PLEKHA1 CDC42 NEDD9 EPB41L3 FGR RHOA ATP2B1 PTPRM ADAM17 ITGA5 LCP1 NDEL1 SPTBN1 SPRY2 ARHGEF2 ATP6V1B2 AMOTL1 MTMR6 PTPRO MEFV ROCK1 PARVB VASP STX3 SSH1 VIM ARHGEF26 ARAP3 ACTR3 WASF3 PLEK ACTG2 UNC5A PAFAH1B1 RUFY3 ACTR2 KANK1 MYO1C FAM107A WASF2 APPL1 MTMR14 RAC2 DUOX1 MTMR9 APBB2 PALM FERMT2 SNX2 PODXL SNX1 GRIA1 DOCK8 SNX9 SPRY4 PKD2 PARD6A APBB1 GABARAPL1 CLASP2 MACF1 ARPC2 EPB41L5 RAB5A TIAM1 CXCR4 USH2A EPHA2 PARVA RAPGEF3 ABI3 ADORA2A PDE4A ARPC5 SAMSN1 IQGAP1 SHISA6 ATF4 SPATA13 PIEZO1	down	*
GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.0000251	0.0013393	0.5756103	-0.2326654	-1.400679	573	FFAR4 CXCL3 HCRTR1 GPR17 EREG RAMP3 AKAP5 FCN1 CXCL16 GPR15 EDNRB PPARG F2RL3 LHCGR ADCY9 P2RY1 GPR65 ADCY4 RAPGEF2 RAMP2 PDE1B HCAR2 CCL3L1 NXPH3 RGS9 CCRL2 INPP5K CAV1 CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 MARCO PDE4C PDCL RHOA PDE2A ANXA1 SSTR1 ADA RAPGEF4 RASGRP4 GNGT2 FZD4 NMUR1 ABHD6 ADRB1 GNG7 ADRB2 ARHGEF2 GPBAR1 PDE4D RHOB GPR4 TAPT1 ROCK2 ARRB1 PTGIR CCL22 DGKE TACR2 PTAFR PRKD3 ROCK1 GRK5 NPR3 PDE8A CCL3 PDE3B P2RY2 GPR85 CXCL2 ARHGEF26 CCL4 PTGER3 XCL2 PLEK GNAQ GPR157 PIK3R5 GNAI2 CALM2 PTH1R GNRH1 S1PR4 HCAR3 METAP1 ADCY2 AREG WASF2 GPR61 PDE6A PDE6B RGS18 TAS1R1 HRH1 ADRA1A RAC2 GPR141 PALM PTGER4 CCR7 PIK3R1 ACKR3 GPR183 PTGER2 NPR1 HOMER1 SUCNR1 CXCL5 PREX2 OGFRL1 RGS13 GPRC5A TPRA1 GPR37L1 GPR3 CALM1 DGKG DAGLA CCR4 SORT1 VAV3 GLRA3 FPR2 NLRP6 GNAI1 GNG5 GPR84 APLP2 GLRA1 MRGPRF CCR1 CRY1 GNA13 ACTN2 OR52B6 RGS2 GPR18 GRK4 PDE4B QRFP CCL20 CCR6	down	**
GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS	0.0012254	0.0251896	0.4550599	-0.2444639	-1.400365	321	SWAP70 TEK DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 TMOD3 CCDC88A INPP5K BAG4 KANK3 CAV1 MYADM BAIAP2 CDC42EP2 ESAM S1PR1 CDC42 CIT SCN5A RHOA SPIRE1 JAM3 RGCC CRK SFRP1 SPTBN1 PDE4D PDGFA SORBS3 RHOB ROCK2 SYNPO TNNC1 BST1 ROCK1 VASP COTL1 C9orf72 ACTR3 CAPZA2 PLEK DSTN ADD1 ARHGDIB ACTR2 LMOD3 HCK MTPN NCKAP1L ARHGAP17 KANK1 MYO1C FAM107A TMOD1 WASF2 SYNPO2 RHOBTB2 RAC2 ARHGEF10 RHOG RHOJ PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 SIGLEC15 PPM1F SNX9 RHOQ WNT11 WHAMMP3 EPHA3 CLASP2 ACTN2 PDE4B ICAM1 ABL2 ARPC2 WDR1 LMOD1 CDC42EP3 TMOD2 ARHGAP18 DIXDC1 RND1 LIMCH1 RAPGEF3 EDN1 ARPC5	down	*
GO_NUCLEAR_CHROMOSOME	0.0000593	0.0025783	0.5573322	0.2752959	1.398207	864	HMGA2 SIM2 MNX1 ONECUT2 ONECUT1 HNF1A TP63 DDX11 FOXM1 FOXA3 RUVBL1 CDC45 MCM10 PAX9 ASCL5 TFAP2A BUB1B HOXD8 NEK2 TRNP1 CCNB1 SOX2 TIMELESS HOXB6 ZFHX4 CPSF6 NPAS1 TSHZ2 THOC3 NDC80 PRIM2 PIF1 BRCA1 SPDEF CREB3L4 FOXD4 SIX4 ZFHX2 GINS1 E2F8 FOXE1 NPAS2 POLE NABP2 IRX6 PLK1 NUF2 AURKB CENPA SIX1 EBF3 TBX19 SOX9 E2F3 TFDP2 FIGNL1 UHRF1 MCM4 HOXB7 MCM2 GRHL3 SP5 ORC1 HNF4G ASXL3 GINS4 NCAPD2 RSPH1 RUVBL2 SMARCD3 SMARCC1 SOX30 STAG3 CHAF1A FOXA1 TP53BP1 FOXJ1 BUB1 MSX2 TOP2A AURKA EME1 CBX3 REC8 POLA2 SYCP2 ATR POLD2 IRF3 SMARCAL1 MCM7 ZNF174 E2F2 MSX1 MMS22L CDCA5 PRKDC TRRAP WDHD1 CSRNP3 HOXC6 HELB MCM3 CHAF1B HORMAD1 SOX4 BRD9 EME2 ZNHIT1 TOPBP1 CHEK1 ORC6 ACTL6A NFYA SOX11 CENPO CSRNP2 RAD51AP1 XRCC1 THAP10 HES6 MGA EHF HSF4 REPIN1 BLM GRHL2 PML HOXB5 MEOX1 TFCP2 PARP1 INCENP ETV7 CBX5 ASF1B CDK1 CDK12 POLE2 BIRC5 PHF12 ZMIZ2 E2F1 TBX15 PRRX2 STAT2 DNA2 POU5F1B FEN1 EZH2 THAP8 TTI1 CBX1 ARNT2 IRF6 TBX1 TELO2 ZGPAT OVOL3 FOXK1 TRIM24 TUBG1 DCLRE1C ALX4 SATB2 ADNP DVL3 RAD9A HIRA RAD51D MTA3 SUDS3 SSRP1 NFATC4 HDAC1 ESCO2 GINS2 ANP32E LRWD1 OTX1 CHD5 CDK13 POLD1 THRB ESR1 ENC1 SLX4 RAD50 NR6A1 ETV4 CENPK PROX1 KLHDC3 EP400 NFXL1 BRD8 HNF1B TWIST1 RPA1 TFCP2L1 NOL6 MCM6 HOXA3 DNMT3A THOC5 WRNIP1 ZNF446 MCM5 ZRANB3 TFAP4 ADD3 NFE2 ESRRA CREB3L2 ETV6 RCC1 SMARCC2 ESRRB ZNF580 MSH4 LHX4 MCRS1 MSH2 SMARCA4 PRIM1 NFRKB GRHL1 BBX MLXIP STAT6 INO80E RAD51 TNKS1BP1 BRMS1 CHMP1A FOXD2 LBX2 SOX12 CHD3 HOXB2 MXD3 SIRT6 SMC2 TONSL TCF3 SRCAP SWI5 TP53 ZBTB32 APEX1 TAF4 NCAPD3 RORC RAD1 SMARCB1 E2F7 RRS1 NAT10 MUC1 THAP3 HOXA6 ZFPM1 ASCL2 ACTR5 SS18L1	up	**
GO_REGULATION_OF_IMMUNE_RESPONSE	0.0000015	0.0001344	0.6435518	-0.2283496	-1.396212	841	GPR17 NLRC4 EREG CD300LF FOXF1 HMOX1 FCN1 GCSAML SCIMP PPARG CD55 FCN3 GATA2 PGC IL1B MNDA LPXN BTNL9 OSCAR FYN SAMHD1 FCER1A CLEC12B CAV1 BAIAP2 PRAM1 MYD88 ELF2 CD300E PLEKHA1 C5AR1 CLEC10A RBM14 ELMO1 CDC42 MARCO IL1RL1 CD1C OTUD4 PSMD5 LAMP1 CD22 SLC11A1 NFATC3 PILRA RFTN1 IL23A CD8A FGR CD36 ANXA1 MIR146A SPG21 CLCF1 IGKV2-28 ADA CD33 RAP1A CLEC7A MASP1 TNIP3 RNF125 FOXP1 HLX PAG1 MS4A1 IFNK SERPINB9 LAIR1 GATA3 PPP3CA RGCC IL18R1 TRAF6 GRN CRK CRTAM PDE4D UBE2D3 TFRC IL10 CFD DUSP3 BIRC2 SLC46A2 PTAFR SOCS5 LY96 FAM49B UBQLN1 NCR3LG1 NFKB1 CADM1 PTPRC IRAK2 SELL TLR4 ACTR3 SFTPD FCER1G CD300C SMAD7 KLRD1 IL7R HLA-DQA1 C4BPB CD300LB ACTR2 TGFB2 PIAS1 HCK NCKAP1L CD8B IGLV2-11 MYO1C CD80 ELF1 IL6 WASF2 MUC3A CD160 KLRB1 CTSS PSEN1 SOCS3 APPL1 HCST SEC14L1 CD48 C1QA JUN PSMA1 RAC2 TYROBP TREM1 HSPA1B DNASE2 IFNGR1 JAK1 RAPGEF1 CCR7 STX7 PIK3R1 PRKCE GRB2 MALT1 RC3H1 PRKACA TBX21 ZNF683 IGKV3-20 CD34 PLCG2 FOS UBB PELI1 CALM1 TNFSF13 YTHDF3 PSMD12 ICAM2 MAPK8 TREX1 CD74 CR1 PIK3AP1 SMPDL3B TGFB1 VAV3 AP1G1 CD1D ZBTB1 TEC FPR2 YTHDF2 NLRP6 PIK3C3 CD86 CNOT7 PDCD1 PPP3R1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 BAG6 FCGRT CLEC2B PDE4B IGKV1D-39 UNC13D ICAM1 TRAC IL18 IL18RAP LAT ARPC2 FKBP1A ARRB2 RTN4 HSP90AA1 TAB2 RIPK2 NLRP3 UBE2D1 ACTB HAVCR2 PSME4 CREBBP ICAM3 CD19 TLR10 SIN3A NFKBIA KIT SIGLEC9 CD1E CD3G ARPC5 PAK2 KLRK1 AIM2 SAMSN1 THEMIS2 ITCH PSMD6 PSMD9 SFPQ PUM1 MS4A2 KLRF1 ABI1 UBE2V1 CYBA EPG5 PPP2R3C IGKV2-30 C5AR2 C1QB CTSH SPPL2A TREML1 CLEC4E C5 MAPK1 PRKCH ITGAL ITGB1 TREM2 S100A8 FPR1 NDFIP1 NFAM1 MUL1 FPR3 CD79B HLA-DRB1 WNT5A PAX5 UBE2N BCL10 MATR3 HMGB1 DDX21 FCGR3A NMI EP300 CD3E IRF1	down	***
GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION	0.0014489	0.0284549	0.4550599	-0.2467402	-1.395628	280	SWAP70 DLC1 WNT4 RDX GPR65 CDH5 ARHGEF15 SHANK3 TMOD3 INPP5K BAG4 KANK3 MYADM BAIAP2 CDC42EP2 ESAM S1PR1 DYRK1A CDC42 CIT RHOA SPIRE1 SLAIN2 RB1 RGCC SFRP1 SPTBN1 ARHGEF2 SORBS3 ROCK2 SYNPO ROCK1 VASP COTL1 C9orf72 ACTR3 CAPZA2 PLEK DSTN ADD1 ACTR2 LMOD3 HCK MTPN NCKAP1L KANK1 MYO1C TMOD1 WASF2 SYNPO2 PSEN1 HSPA1B ARHGEF10 PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 PPM1F SNX9 WNT11 TTBK2 WHAMMP3 CLASP2 ACTN2 ICAM1 ARPC2 WDR1 LMOD1 CDC42EP3 TMOD2 ARHGAP18 HSPA8 LIMCH1 RAPGEF3 EDN1 ARPC5 SYNPO2L CAMSAP2 LDLR	down	*
GO_MUSCLE_SYSTEM_PROCESS	0.0009452	0.0213338	0.4772708	-0.2403501	-1.395042	341	SCN4A HMOX1 STAC EDNRB IL1B P2RY1 TRPC3 TMOD3 CAV1 NEDD4L CALCRL ADRA1D TBXA2R MEF2A SCN5A RHOA MYOZ1 ATP2B1 ADA LMNA CHRNE NMUR1 DES PPP3CA ADRB2 TCAP PDE4D SGCA SETD3 TMEM38B CNN1 SORBS3 MAP2K3 ROCK2 TNNC1 FOXO1 KCNMA1 SORBS1 NPNT TACR2 PTAFR KLF4 ROCK1 GAA CDK9 VIM MIR24-2 PTGER3 PIK3C2A SMAD7 RAP1GDS1 ACTG2 MYH11 CALM2 MIR17HG LMOD3 MTPN SRF KCNA5 SLC8A1 SCN4B TMOD1 UTRN NOTCH1 ADRA1A PDE5A GSTO1 PRKACA HOMER1 LMCD1 CALM1 FOXO3 MYL12A MIR23A KCNN2 SLC8A3 GLRA1 MYOCD GATA6 ACTN2 RGS2 PDE4B PDLIM5 SCN7A LMOD1 TIAM1 CXCR4 TMOD2 GPD1L KIT EDN1 PRKG1 P2RX1 DOCK4 SMAD4 EHD3 SPHK1 CYBA KLF15 KCNE1 FKBP1B GJC1	down	*
GO_TAXIS	0.0000960	0.0037434	0.5384341	-0.2349754	-1.394732	507	TNR DAB1 SEMA6B SEMA3G CXCL3 SEMA6A IL1A SWAP70 CXCL16 EDNRB ROBO4 SPN IL1B DPYSL2 PLA2G10 BDNF FYN SHANK3 EGR2 CCL3L1 ECSCR CCRL2 FOSL1 CDH13 BMPR2 C5AR1 S1PR1 FGF10 DSCAML1 IL1RN GAS6 IL23A RHOA SEMA6D ANXA1 PLA2G7 PTPRM SEMA3B HBEGF SBDS ADAM17 PLXNA2 HSPB1 RANBP9 GATA3 NR4A1 JAM3 PLXNA4 CRK SPTBN1 WNT3A PDE4D PDGFA IL10 DUSP3 CCL22 PTPRO BST1 ZSWIM6 PTAFR PLAUR PSPN VASP THBS1 STX3 KLF7 CCL3 CXCL2 ID2 CCL4 SFTPD XCL2 FCER1G DUSP1 MATN2 OXSR1 UNC5A AKIRIN1 SIAH1 TGFB2 NCKAP1L FLT1 IL6 LAMB2 NOTCH1 HRH1 RAC2 CNTN4 RHOG APBB2 CCR7 DAPK2 PIK3R1 ACKR3 GRB2 GPR183 CREB1 SUCNR1 CXCL5 PPM1F CD74 BIN2 CCR4 EPHA3 TGFB1 VAV3 ITGA9 FPR2 IRS2 LGALS3 DOK2 KLRC4-KLRK1 CCR1 NPTN GPR18 ADAM10 PDE4B CCL20 CCR6 FGF2 ARRB2 SEMA4A TIAM1 CXCR4 EPHA4 CCR9 PTCH1 EPHA2 PARVA PLGRKT RET KIT EDN1 KLRK1 B3GNT2 MTUS1 LYST FGFR1 NRP2 DOCK4 NRG1 GRB10 IL16 SMAD4 FEZ1 ANO6 FEZ2 RAP1GAP GREM1 SERPINE1 C5AR2 CNR2 CX3CR1 C5 MAPK1 MYH10 TREM2 S100A8 FPR1 NOG EFNB2 PIK3CG CALR FPR3 BSG	down	**
GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS	0.0001887	0.0063548	0.5188481	-0.2375723	-1.389854	417	SIGLEC11 NLRC4 EREG CD300LF SASH1 FCN1 SCIMP SIGLEC16 PPARG CD55 PGC IL1B MNDA FYN LY86 SAMHD1 CLEC12B CAV1 MYD88 CLEC10A RBM14 MARCO OTUD4 PSMD5 LAMP1 TRIB1 RFTN1 IL23A FGR CD36 MIR146A CARD16 CLEC7A TNIP3 RNF125 FOXP1 IFNK SERPINB9 TRAF6 GRN CRK CRTAM UBE2D3 BIRC2 SLC46A2 LY96 UBQLN1 NFKB1 CADM1 IRAK2 TLR4 SFTPD FCER1G ZMPSTE24 PIAS1 HCK MUC3A CD160 CTSS SOCS3 APPL1 SEC14L1 PSMA1 CARD8 HSPA1B IFNGR1 JAK1 PRKCE MALT1 UNC13B PRKACA PLCG2 UBB PELI1 YTHDF3 PSMD12 ICAM2 TREX1 CR1 PIK3AP1 SMPDL3B AP1G1 CD1D FPR2 YTHDF2 NLRP6 PIK3C3 CNOT7 KLRC4-KLRK1 IFNLR1 SYT11 IL18RAP ARRB2 RTN4 TAB2 RIPK2 UBE2D1 HAVCR2 PSME4 CREBBP ICAM3 TLR10 SIN3A NFKBIA PAK2 KLRK1 AIM2 ITCH PSMD6 PSMD9 SFPQ PUM1	down	**
GO_MITOCHONDRIAL_ENVELOPE	0.0005647	0.0149604	0.4772708	0.2779767	1.389131	590	CPS1 HKDC1 BIK CEP89 BDH1 GPAT2 FLVCR1 COA1 CHCHD6 SLC25A21 SORD THEM4 MRPL46 ANKZF1 MSTO1 NDUFS6 TOMM34 ACAD9 ALDH18A1 SFXN1 NNT PRKCA CYP27B1 TYMS COX6B2 SHMT2 MRPS35 COQ3 COX11 AGK UQCC1 TAMM41 NME1 IKBKE NDUFB8 CISD1 GOLPH3 SDHA QTRT1 MRPL15 CYP24A1 GPER1 BPHL NDUFS2 TMEM177 COASY GCAT AKAP1 ERAL1 MRPL3 MRPL27 BLOC1S1 LETMD1 BRI3BP ABCB6 ASS1 COX19 SLC25A39 TIMM50 MRPS11 FDXR MRPS30 MTG1 PHB SLC25A10 UQCR11 COQ9 THOP1 MRPL36 MRPL37 GOT2 TRAP1 L2HGDH MRPS2 SLC25A13 MRPL17 COA4 MRPS12 ATAD3A NLN UQCC2 CPT1B CHCHD3 NRGN ULK1 CHCHD2 MYO19 IFI27L2 UQCRFS1 GNPAT NDUFA11 SPG7 COA3 FOXRED1 SPATA18 MTOR SLC25A18 MRPS34 DHODH C19orf12 MRPL11 MRPL52 COX7C PPOX DTYMK MRPL4 AGPAT5 DAP3 DNAJC11 NDUFA13 ACSL6 COX10 TIMM13 STOML2 CHCHD1 SIRT4 MRPS23 BCL2L1 BAD NAT8L MRPL24 MRPS33 CKMT2 MRPL28 MRPL41 ROMO1 SIRT5 MRPL53 HAX1 PRODH NDUFS7 MRPL51 SUOX PLEKHN1 NDUFV1 MRPL14 SCO2 MLXIP VDAC1 MRPS25 MRPL55 NME4 UQCRC1 LPIN1 HK2 TOMM40L COX5B SLC25A29 MCU MRPL9 TRAK1 MRPL21 AIFM2 MICU1 NDUFA8 NDUFS8 RHOT2 CPOX AURKAIP1 VDAC3 UQCRQ CIAPIN1 CPT1C TIMM44 FIS1 MRPS27 SFXN4 SFXN5 MRPL20 MRPL48 PI4KB NDUFB7 COX6B1 DNM1L MRPS26 IMMP2L COX17 CYP11A1 MTG2 ACSL5 CYB5B TOMM7 RTN4IP1 NDUFAF6 SFXN2 BMF MRPS16 UCP3 SPHK2 MRPL12 CRAT PARL MRPL43 OPA1 RSAD2 BAK1 MRPL2 TOMM40 TIMM10	up	*
GO_LEUKOCYTE_DIFFERENTIATION	0.0002367	0.0077130	0.5188481	-0.2386810	-1.389093	430	CD101 TAL1 PPARG HHEX GATA2 SPN SNX10 DCSTAMP WNT4 OSCAR LYL1 PDE1B CDC42 GAS6 TGFBR2 TRIB1 LILRB3 IL23A CD8A RHOA ANXA1 CLCF1 FBXO7 ADA ADAM17 KLF10 FOXP1 KLF6 HLX MS4A1 IFNK GATA3 RB1 IL18R1 TRAF6 SFRP1 ZEB1 SPI1 TFRC ZMIZ1 EVI2B IL10 NRARP SLC46A2 FUT7 CEBPA SOCS5 CCL3 PTPRC AXL ID2 TLR4 FCER1G SMAD7 INHBA IL7R UBASH3B CYP26B1 PAFAH1B1 MIR17HG SRF NRROS NCKAP1L RBPJ CD80 IL6 PKNOX1 PSEN1 JUN MITF CUL4A TYROBP JUNB OSTM1 PTGER4 CCR7 SP3 PIK3R1 CD83 GPR183 CREB1 MALT1 SIGLEC15 RC3H1 AP3B1 FSTL3 TBX21 RASSF2 ZNF683 PLCG2 FOS RRAS AZI2 RUNX3 CD74 CR1 TGFB1 CD1D ZBTB1 JMJD6 CBFA2T3 CD86 CD81 CCR1 MFNG GPR18 CCR6 IL18 SEMA4A RIPK2 NLRP3 TOB2 CCR9 EPHA2 CD19 KIT DOCK10 CD3G DNAJB9 TNFSF9 RORA	down	**
GO_RESPONSE_TO_HORMONE	0.0000087	0.0005476	0.5933255	-0.2262844	-1.388694	767	SLC6A4 HCRTR1 EREG ZNF366 RAMP3 LPIN2 TEK EDNRB PPARG ADTRP HHEX SFRP4 CPEB2 WFDC1 IL1B LHCGR CAT ADCY9 RDX ADCY4 PTPRE RAMP2 PID1 ENG KL PCSK9 FYN LPL EGR2 LMO2 RGS9 INPP5K CAV1 BAIAP2 FOSL1 CRY2 VAMP2 ADCYAP1R1 TBXA2R RBM14 FGF10 PRKAR1A RXFP1 NR3C1 TGFBR3 IL1RN CBL TGFBR2 CASP9 RHOA TXNIP ANXA1 SSTR1 ATP2B1 LATS2 BTG2 ANXA5 ABCG1 FOXP1 CAV2 ADIPOR1 EIF4E NR4A1 RB1 NFE2L2 NDEL1 CRK SFRP1 KANK2 EPM2AIP1 HNRNPU ATP6V1H ATP6V1B2 FOXC2 NODAL IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 PTAFR REST KLF9 ROCK1 DAB2 THBS1 ARNTL BCHE SOCS2 ATP6V1D NFKB1 CDKN1A PDE3B NR1D2 SIK2 ATP6V0D2 IGFBP2 LBH PER1 DUSP1 PIK3C2A INHBA ADIPOR2 MBD2 GNAQ GNAI2 TBC1D4 ANXA3 NCOA1 TGFB2 MMP19 GLB1 PIAS1 GNRH1 SRF BTG1 PRCP SLC25A33 PDK4 UFM1 KANK1 MYO1C FAM107A CREBRF ADCY2 AREG IL6 CTSS SOCS3 APPL1 RAB8B RWDD1 JUN DHH STAT4 NOTCH1 RAB31 USO1 GAS2L1 ETS1 ADRA1A DDX17 ATP6V0B JUNB DNAJA1 PTGER4 CCR7 PIK3R1 DDX5 PRKCE GRB2 CREB1 PTGER2 RAB8A MT-ND3 PRKACA EGLN2 ACSL1 FOS ATP6V0D1 RHOQ CACYBP FOXO3 SRSF6 FOSB DDX18 HNRNPD SORT1 TIMP2 STXBP3 TGFB1 NR2C1 SRSF4 TGFB1I1 GNAI1 ATP6V1A MMP15 IRS2	down	***
GO_REPRODUCTION	0.0000447	0.0020793	0.5573322	0.2707800	1.383174	1006	TSPAN8 SYT8 PRLR TRIP13 TP63 ABCC2 BRINP1 SPATA24 SPATA25 MYCBPAP FOXA3 BIK PPP1R1B CYP19A1 RUVBL1 PMFBP1 FBXW8 SPINK13 BUB1B NUP107 NEK2 CCNB1 WFDC2 NPAS1 MND1 DPY19L2P1 SLC2A1 CLGN SORD GAL3ST1 CREB3L4 SIX4 ZP3 TTK RACGAP1 LHB E2F8 CATSPERB SLC26A8 SPP1 ASPM EIF2B5 TTC26 PLK1 NUF2 IFT27 PTTG1 ESPL1 B4GALNT1 SOX9 FIGNL1 STC2 RBBP8 CYP27B1 SPINT2 RAD54B CDC25A UMPS XRCC2 NOX5 CCNF APOL2 SPINK1 CIB1 TDRKH MCM8 MAP2K6 SRPK1 INSRR NCAPD2 CCT2 TNC DNAI1 RSPH1 ITGA2 ZSCAN2 OSBP2 CASP2 EXO1 NUDT1 STRA6 DLG1 SMARCC1 SOX30 STAG3 RPL39L FOXA1 SPAG16 DPY19L2P2 CUL7 FBXO43 FOXJ1 TSGA10 FRS2 PAFAH1B3 BUB1 FANCA MSX2 TOP2A IDO1 CCT5 AURKA EME1 AGT REC8 ODF2 SYCP2 VASH2 MSX1 POC1A IL12B DPCD MDFI PRKDC SPEF2 RHOBTB3 TEKT2 SGPL1 PCDHGA4 NSUN2 HOOK1 RAD54L FANCD2 PLTP WDR66 HORMAD1 CDC25C ANG MDK NME5 EGFR OAZ3 EME2 CGB7 SPINT1 HSF2BP GAS8 RAB13 MST1R OXTR DNAH11 BRIP1 DDR1 CAD GNPDA1 SPAG8 PTGDR2 GRHL2 CCDC136 ALDOA CCDC40 BMP5 MEA1 IGFBP5 ASF1B LRGUK LRRC6 CDK1 LRP2 MERTK PICK1 CCT3 GOT2 SUN1 E2F1 ITGB8 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 SEMA3A DNAH5 TCTE1 RTCB ACVR1B SRD5A1 STK11 LGR5 GOLGA3 FANCG CATSPERG CCNE1 ST14 PABPC1L CATSPER3 NPHP1 TUBG1 VIPAS39 GGT2 TSNAXIP1 ADNP MTOR CTSV MNS1 ADAM28 DHODH RAD51D IQCG MORN2 UBE2Q1 PCSK4 GAS2 FZR1 TSSK3 SPAG1 MMP7 TEKT3 TAC4 SPA17 PRMT7 SPATA32 SLC4A2 KRT19 GNRH2 CHD5 THRB ESR1 TYRO3 SLX4 CCT7 RAD50 NR6A1 KDM3A ANKRD31 EPN1 KLHDC3 PTN MEI1 CDC20 ROPN1B TUBG2 AAAS BCL2L1 CATSPER2 RPA1 BAD TFCP2L1 FANCM KRT8 DNMT3A	up	**
GO_REGULATION_OF_DEFENSE_RESPONSE	0.0000263	0.0013870	0.5756103	-0.2289450	-1.381841	610	FFAR4 SIGLEC11 GPR17 NLRC4 EREG ACP5 CD300LF IL17RB FOXF1 FCN1 TEK EDNRB SCIMP SIGLEC16 PPARG PGC WFDC1 IL1B FABP4 MNDA CDH5 FYN LPL SAMHD1 CLEC12B CAV1 CALCRL MYD88 CLEC10A RBM14 MARCO CASP12 IL1RL1 OTUD4 PSMD5 LAMP1 RFTN1 IL23A FGR DNASE1L3 PDE2A APOD CD36 ANXA1 MIR146A PLA2G7 ADA CLEC7A TNIP3 RNF125 FOXP1 IFNK SERPINB9 GATA3 SIRPA RB1 TRAF6 GRN CRK CRTAM UBE2D3 CASP5 SLC7A2 IL10 BIRC2 MEFV CASP1 BST1 SLC46A2 KLF4 CEBPA SOCS5 LY96 UBQLN1 CCL3 NFKB1 CADM1 NR1D2 PTPRC IRAK2 TLR4 PTGER3 SFTPD FCER1G PER1 ZMPSTE24 PTGIS PIAS1 HCK IL17D IL6 MUC3A CD160 CTSS SOCS3 APPL1 SEC14L1 PSMA1 ETS1 HSPA1B IFNGR1 JAK1 PTGER4 CCR7 PRKCE OSM MALT1 UNC13B PRKACA SUCNR1 CST7 PLCG2 UBB PELI1 BCL6B YTHDF3 PSMD12 ICAM2 TREX1 CR1 PIK3AP1 SMPDL3B AP1G1 CD1D CD6 FPR2 YTHDF2 NLRP6 PIK3C3 CNOT7 CD81 KLRC4-KLRK1 IFNLR1 SYT11 IL18 IL18RAP ARRB2 RTN4 TAB2 RIPK2 NLRP3 UBE2D1 HAVCR2 PSME4 CREBBP ICAM3 TLR10 SIN3A NFKBIA ADORA2A CTSC PAK2 KLRK1 AIM2 RORA ITCH LDLR PSMD6 PSMD9 SFPQ PUM1	down	**
GO_REGULATION_OF_CELL_CYCLE	0.0000531	0.0023712	0.5573322	0.2695857	1.378046	1008	HMGA2 CCNO PKHD1 MCIDAS TRIP13 DDX11 FOXM1 CEP72 SPICE1 BRINP1 KIF20A MDM1 CDC45 TICRR CHEK2 BUB1B NEK2 TRNP1 CCNB1 SOX2 CENPF TIMELESS PAGR1 STOX1 NDC80 TBRG4 BRCA1 TTK CDK4 SMPD3 RACGAP1 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN CNTD2 ASPM NABP2 STIL CEP70 PLK1 AURKB PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 E2F3 TFDP2 CCNB2 FIGNL1 RBBP8 PRKCA CDC25A MYBL2 PRC1 ORC1 CCNF DTL MAP2K6 ZFYVE19 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 CASP2 HMMR BTRC SMARCD3 DLG1 NLE1 KIF23 FOXA1 MKI67 CUL9 CUL7 TP53BP1 FBXO43 KNTC1 RHNO1 KIF3B BUB1 LGMN MSX2 TOP2A MAP10 GPER1 AURKA EME1 CBX3 ODF2 ATR SFI1 TPR MAD1L1 E2F2 MSX1 POC1A CLSPN CXCR5 IL12B RRM2 TTLL12 CDCA5 PRKDC FSD1 NSUN2 TOM1L1 KIF11 GPSM2 HORMAD1 CDC25C SOX4 TGM1 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 SOX11 MDM2 AKT2 MGA PKMYT1 BRIP1 FBXL8 BLM PML CNOT3 ERCC2 MNAT1 STXBP4 SKP2 PES1 PSRC1 PTPN3 INCENP KNSTRN CKS1B TTBK1 AFAP1L2 CDKN2C NUSAP1 CBX5 ANAPC5 ING4 CTDSP2 CDK1 CDK12 CEP97 CENPJ RFWD3 GMNN E2F1 PSMB5 CCNJL TMEM8B DNA2 ANAPC7 FEN1 EZH2 CNOT11 SPAG5 EGF TAF6 METTL3 RAB11FIP4 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 FGFR1OP STK11 IRF6 GIPC1 MYO19 ANKK1 CEP63 INTS7 CCNE1 CEP192 CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 MTOR NINL TACC3 RAD9A PSME2 RAD51D MTA3 TRIM37 FBXO4 MYBBP1A GAS2 FZR1 PKP4 NUDT16 CGREF1 KIF20B LAMTOR2 LIN37 SMIM22 TRIM32 ASNS SGSM3 ANAPC1 SND1 CDK13 PSMD2 ATAD5 CABLES2 CDC7 ANKRD31 PROX1 SH2B1 CENPV CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B	up	**
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE	0.0011311	0.0240742	0.4550599	0.2771998	1.374404	530	HMGA2 TRIP13 FOXM1 BRINP1 MDM1 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 SOX2 CENPF TIMELESS NDC80 TBRG4 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB PTTG1 ESPL1 CDC6 TFDP2 RBBP8 ORC1 CCNF DTL MAP2K6 ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 NLE1 TP53BP1 FBXO43 KNTC1 RHNO1 BUB1 TOP2A GPER1 AURKA EME1 CBX3 ATR TPR MAD1L1 CLSPN IL12B RRM2 PRKDC NSUN2 TOM1L1 HORMAD1 CDC25C SOX4 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 SOX11 MDM2 AKT2 MGA BRIP1 BLM PML CNOT3 PTPN3 CDKN2C CBX5 ING4 CTDSP2 CDK1 RFWD3 GMNN E2F1 PSMB5 DNA2 EZH2 CNOT11 TAF6 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 STK11 IRF6 CEP63 INTS7 CNOT2 PSMA5 MTOR RAD9A PSME2 TRIM37 FBXO4 MYBBP1A GAS2 FZR1 CGREF1 KIF20B LAMTOR2 SGSM3 PSMD2 CDC7 PROX1 L3MBTL2 PSMB3 CDC20 BCL2L1 CHMP4C WNT10B CDK5RAP2 THOC5	up	*
GO_RESPONSE_TO_LIPID	0.0000188	0.0010693	0.5756103	-0.2270524	-1.373848	720	SLC6A4 SMAD6 RBP4 CXCL3 SLPI ACP5 KMO ZNF366 RAMP3 IL1A SASH1 EDNRB SCIMP PPARG ADTRP CD55 GATA2 WFDC1 IL1B TIE1 CAT RAMP2 THBD PID1 INSIG1 ENG LPL LY86 RGS9 CAV1 FOSL1 CRY2 MYD88 ADCYAP1R1 TBXA2R C5AR1 FGF10 NR3C1 TGFBR3 IL1RN CBL SLC11A1 TGFBR2 TRIB1 CASP9 RHOA TXNIP BRINP3 CD36 ANXA1 MIR146A SSTR1 ATP2B1 CARD16 ADAM17 TNIP3 FZD4 LITAF ABCG1 FOXP1 EIF4E NR4A1 SIRPA RB1 TRAF6 SFRP1 WNT3A KANK2 HNRNPU PDE4D NODAL IL10 ROCK2 PTGIR FOXO1 CASP1 PTAFR KLF4 REST ID3 KLF9 DAB2 THBS1 ARNTL BCHE SOCS2 LY96 CCL3 NFKB1 CDKN1A NR1D2 KCNMB1 CXCL2 IRAK2 VIM SELP AXL TLR4 IGFBP2 LBH PER1 DUSP1 INHBA CPT1A MBD2 CYP26B1 IL24 ANXA3 NCOA1 TGFB2 GLB1 PIAS1 GNRH1 HCK PDK4 UFM1 WNT9A FAM107A CREBRF CD80 ADCY2 AREG IL6 RWDD1 AQP3 JUN DHH NOTCH1 ETS1 DDX17 CARD8 JUNB DNAJA1 PTGER4 CCR7 IRF8 DDX5 PRKCE CREB1 PTGER2 MALT1 MT-ND3 CXCL5 EGLN2 ACSL1 PLCG2 FOS ADNP2 PELI1 MAPK8 FOSB WNT11 DDX18 HNRNPD EPHA3 TGFB1 AKIRIN2 NR2C1 CD6 TGFB1I1 GNAI1 MMP15 IFNAR1 CD86 PIM1 PLSCR4 KLRC4-KLRK1 WBP2 CRY1 PLAA PDE4B TSPO RXRA SMAD2 JUND NR2E3 ICAM1 IL18 ABL2 TFPI ARRB2 OSR1 VPS4B TAB2 RIPK2 NLRP3 PTCH1 HAVCR2	down	**
GO_ENDOSOME	0.0000039	0.0002898	0.6105269	-0.2266653	-1.373419	742	SLC6A4 RAB11FIP1 SLC31A2 MCOLN1 ACE GPR15 SGK3 OSBPL11 FGD5 OSBPL1A TMEM150B LHCGR SNX10 DCSTAMP PTP4A2 RAPGEF2 HSD17B6 RAB3C PCSK9 ARRDC4 FIG4 FOLR1 FYN SNX32 PLEKHF2 CAV1 CORO1C NEDD4L CALCRL MYD88 ADCYAP1R1 S1PR1 ARL8B CD1C LAMP1 CD22 SLC11A1 RFTN1 GGA2 RHOA NUMB ANXA1 SPG21 RRAGC MCTP1 RILP RAP1A CHMP1B ZDHHC2 PICALM LITAF ABCG1 CYB561A3 ABHD6 ADRB1 ADRB2 TRAF6 GRN LAMTOR3 WNT3A ZFYVE16 UBE2D3 TFRC RAB14 RHOB ARRB1 RAB12 DENND6A AOC3 ITM2B LEPROTL1 CDIP1 UHRF1BP1L MVB12B MYO1B GAPVD1 LY96 CTSD TMBIM1 IRAK2 AQP4 C9orf72 ATP6V0D2 TLR4 ARC M6PR SFTPD PLEKHB2 PRF1 EPS15 WDR48 HTT VAMP5 TM9SF2 FKBP15 HLA-DQA1 BACE1 CMTM6 PI4K2A RASGEF1B SIAH1 TBC1D5 SNX3 TMEM9B CD8B VAMP3 FLT1 WASF2 VPS37A GPR61 CTSS KIF13A PSEN1 IL2RB INPP5B APPL1 MAGI2 RAB8B PIKFYVE RAB31 SFTPB OSBPL9 ATP6V0B ATP11A VPS26A JAK1 TBC1D12 RAPGEF1 SNX2 STX7 EEA1 ACKR3 PI4K2B GRB2 RAB8A SNX1 GRIA1 TRAK2 UVRAG APH1B CLN3 CST7 OCIAD1 FGFR4 TMEM192 ATP6V0D1 UBB CD164 PTP4A1 EHD2 TRAPPC10 CD74 MME EPHA3 SORT1 EHD1 NIPA2 AP1G1 SFTPC CD1D VAMP4 ZFYVE9 SBF2 MTMR2 TMEM230 IFNAR1 PIK3C3 ATP6V0C ANKRD13A FCGRT STX12 VPS39 CLCN6 SYT11 UNC13D LDLRAD4 ARPC2 SLC31A1 CHMP3 ARRB2 PARM1 RAB5A ACAP2 TPT1 ATP9B CXCR4 VPS4B EPHA4 TAB2 GIMAP5	down	***
GO_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE	0.0015945	0.0304287	0.4550599	-0.2436178	-1.372304	274	FCN1 ACE PECAM1 GPIHBP1 BTNL9 CDH5 ENG PCSK9 FOLR1 CCRL2 CLEC12B CDH13 S1PR1 TGFBR3 IL1RL1 CD1C CD9 LAMP1 TGFBR2 ABCB1 CD8A HEG1 CD36 ANXA1 CD5 ADA CD33 LIFR ABCG2 ITGA5 CLEC14A ANXA5 ABCG1 ANPEP MS4A1 TMEM123 TFRC THBS1 ABCC4 PTPRC AQP4 SELL SELP TLR4 FCER1G KLRD1 IL7R CD80 IL2RB CCR7 ACKR3 CD83 RTN4R TNFRSF9 MCAM CD34 CD74 CCR4 CD1D CD6 CD86 PDCD1 GLRA1 KLRC4-KLRK1 IGHV3-23 CCR1 FCGRT MR1 CCR6 ICAM1 CXCR4 ITGAE CCR9 BCAM CD19 KIT CD1E CD3G SCUBE1 KLRK1 P2RX1 LDLR	down	*
GO_PROTEIN_HETERODIMERIZATION_ACTIVITY	0.0019948	0.0351383	0.4317077	-0.2392496	-1.371805	307	PRMT8 RBP4 EPAS1 TAL1 PPARG SLC51B P2RY1 BMP2 CAV1 PAFAH1B2 MEF2A BCL2A1 VAPA CLCF1 FBXO7 RRAGC SLC3A1 FZD4 ABCG1 CAV2 ADIPOR1 ADRB1 PPP3CA NR4A1 JAM3 MCL1 PDGFA SDCBP AOC3 ARNTL MAFG NFKB1 NPAS3 ITGAX ATF3 IRAK2 AXL JAM2 TLR4 TAF9 GCA INHBA ADIPOR2 PEF1 ADD1 ANO2 TAF13 TGFB2 HEXB SRGAP2C TFAP2E PPP2CA ADCY2 PKNOX1 TAS1R1 JUN GABPA ADRA1A SNX2 PIK3R1 MAPK4 SNX1	down	*
GO_PHOSPHOLIPID_METABOLIC_PROCESS	0.0012059	0.0248379	0.4550599	-0.2368921	-1.366579	352	GPD1 LPIN2 PNPLA6 ABHD5 TEK PLA2G10 MBOAT2 TTC7B PCSK9 FIG4 LPL INPP5K PTPMT1 GPCPD1 PLEKHA1 INPP5A IDI1 CDC42 AGPAT4 FGR PLA2G7 SLC44A2 SGMS2 SERINC1 ABHD6 APOC1 PDGFA TMEM38B RAB14 FABP5 MTMR6 DGKE PIP5K1B ACSL3 KLF4 SOCS2 SOCS5 PLBD1 CDS2 PIK3C2A PLEK PAFAH1B1 PIK3R5 NUS1 PLCD1 EFR3A PI4K2A HEXB SACM1L CLN8 FLT1 DDHD1 SOCS3 INPP5B PLEKHA3 PIKFYVE MTMR14 MTMR9 CCR7 PNPLA8 PIK3R1 PI4K2B LPCAT2 IP6K1 PLCG2 PNPLA3 SMPDL3B CHPT1 TGFB1 DDHD2 VAV3 ENPP6 DPM1 FPR2 MTMR2 PIK3C3 CD81 GATA6 PLAA CSNK2A2 SERINC3 PLA2G15 FGF2 RAB5A PIP4K2A GPD1L CD19 CEPT1 KIT PTEN FDFT1 FAM126B LDLR	down	*
GO_RECEPTOR_REGULATOR_ACTIVITY	0.0017594	0.0326794	0.4550599	-0.2388984	-1.364295	288	ANGPT4 SEMA6B SEMA3G CXCL3 SEMA6A EREG IL1A CXCL16 ENDOU GPIHBP1 IL1B WNT4 GREM2 BMP2 KL PCSK9 BDNF CCL3L1 CLEC12B CDC42EP2 FGF10 IL1RN GAS6 IL23A SEMA6D CLCF1 BMP1 SEMA3B HBEGF MTRNR2L8 IFNK GRN WNT3A PDGFA NODAL IL10 MTRNR2L3 CCL22 TNFSF12 PSPN TNFSF15 CCL3 EPGN CXCL2 CCL4 XCL2 INHBA INSL6 IL24 TGFB2 GNRH1 WNT9A IL17D CNTF AREG IL6	down	*
GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS	0.0001189	0.0044311	0.5384341	-0.2285843	-1.364257	542	HCRTR1 ZNF366 RAMP3 LPIN2 PPARG ADTRP CPEB2 IL1B LHCGR ADCY9 RDX ADCY4 PTPRE RAMP2 PID1 KL PCSK9 FYN LPL LMO2 INPP5K CAV1 BAIAP2 CRY2 VAMP2 PRKAR1A RXFP1 NR3C1 CASP9 RHOA ANXA1 SSTR1 ATP2B1 LATS2 ANXA5 FOXP1 CAV2 ADIPOR1 EIF4E NR4A1 RB1 NFE2L2 NDEL1 CRK SFRP1 KANK2 HNRNPU ATP6V1H ATP6V1B2 FOXC2 NODAL IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 REST KLF9 ROCK1 DAB2 ARNTL SOCS2 ATP6V1D NFKB1 PDE3B NR1D2 SIK2 ATP6V0D2 IGFBP2 LBH PER1 DUSP1 PIK3C2A INHBA ADIPOR2 GNAQ GNAI2 TBC1D4 NCOA1 PIAS1 PRCP SLC25A33 PDK4 UFM1 KANK1 MYO1C FAM107A CREBRF ADCY2 CTSS SOCS3 APPL1 RAB8B RWDD1 JUN NOTCH1 RAB31 USO1 GAS2L1 DDX17 ATP6V0B JUNB DNAJA1 PTGER4 PIK3R1 DDX5 PRKCE GRB2 CREB1 PTGER2 RAB8A MT-ND3 PRKACA EGLN2 ACSL1 FOS ATP6V0D1 RHOQ FOXO3 FOSB DDX18 HNRNPD NR2C1 TGFB1I1 ATP6V1A IRS2 ATP6V0C WBP2 CRY1 GATA6 ACTN2 KAT2B RXRA JUND NR2E3 ICAM1	down	**
GO_STRUCTURAL_MOLECULE_ACTIVITY	0.0027513	0.0439774	0.4317077	0.2757894	1.360934	491	COL17A1 TFPI2 FGA MYBPH KRT5 COL24A1 LAD1 NUP107 CENPF MUC4 PKP1 COL27A1 ZP3 MRPL46 TUBB2B MUC5AC COLQ COL28A1 ENAM PCLO COL7A1 YEATS4 KRT16 COL22A1 PLS1 COPB2 VILL MRPS35 MYL6B KRT15 TNC CLDN1 MUC6 DLG1 MAP7 LAMC2 RPL39L BICD1 MRPL15 COPG2 COPG1 MYBPC2 SPTB NUP155 ODF2 TPR FLG FGG CD2AP MRPL3 MRPL27 LMNB1 NEB MRPS11 MRPS30 KLHL3 CLDN9 MYOT MRPL36 LAMB4 CLDN15 MRPL37 KRT18 CROCC ERC2 MRPS2 MRPL17 COL3A1 NUP205 MRPS12 IMPG2 NPHP1 COL1A1 TUBG1 COL1A2 COL9A2 MRPS34 TUBB2A TUBA3D MRPL11 COL5A2 MRPL52 TUBA8 PRG4 SPTBN2 MRPL4 CLTA DAP3 KRT19 CHADL EPB41L4B NUP85 CLTB COL11A1 VPS25 TUBG2 HMGA1 MRPS23 MRPL24 UPK1B MRPS33 COMP MRPL28 MRPL41 RPL7L1 COL5A3 BSN ADD3 CLDN16 MRPL51 ANK3 NEFH NUP62 SPAG4 MRPL14 RPS26 MRPS25 MRPL55 TUBGCP4 TUBA4B ANK2 SEC13 FBN2 COPA FMOD MRPL9 MRPL21 LLGL1 CPOX VWA1	up	*
GO_SUPRAMOLECULAR_POLYMER	0.0011469	0.0241867	0.4550599	0.2699787	1.360086	694	KIF1A SAA1 KIF12 KLC3 KIF20A MYBPH MDM1 KRT5 PKP2 DNAH2 RPGRIP1L NEK2 TNNI1 KIF18B PKP1 COL27A1 SLC2A1 TUBB2B RACGAP1 GTSE1 KIF14 SPAG17 ASPM PLK1 KRT16 AURKB TPX2 CMYA5 DNAH3 PRC1 PLS1 DYNC1I1 CCT6A KIF27 MYL6B CDK5RAP3 KRT15 DNAH14 CCT2 DCTN2 NME1 MICALL2 DNAI1 HAUS5 RSPH1 TTLL4 TNNT2 NOS1AP DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 KNTC1 KIF3B FBF1 IDO1 MAP10 MYBPC2 CCT5 GPER1 AURKA ODF2 FLG KIF2C CD2AP MAP1LC3C TEKT2 FSD1 HOOK1 DCDC2 FHOD3 KIF11 LMNB1 DNAH8 NEB GAS8 KIF3C DNAH11 FLNB ALDOA TRPV4 MYO1A PSRC1 INCENP KNSTRN MYOT NUSAP1 PAK1 KRT18 CDK1 DNAH6 KIF5A CENPJ BIRC5 CCT3 TTLL9 JAKMIP1 SCTR TNNI2 KIF19 SPAG6 KIF2A NARF KIF7 COL3A1 DYNLL2 SPAG5 DNAH5 KLHL22 EIF6 UPP2 COL1A1 TUBG1 COL1A2 DNAH7 DNAJA3 NINL LMNB2 MNS1 TUBB2A TUBA3D KIF22 KY COL5A2 DNM1 DBN1 TUBA8 SCN8A KIF21A GAS2 HID1 MAP6D1 KIF20B TRIM32 SMTNL1 KRT19 FHL2 AHNAK2 TWF1 POLB CCT7 COL11A1 KLC2 KLC4 CKAP5 ABCC9 TUBG2 TTLL3 FBXO22 CDK5RAP2 KRT8 DYNC1LI2 KIF21B EML6 TBCA CKAP2 COL5A3 DNAI2 KPTN ANKRD1 HAUS6 DYNC2H1 FAM161A RAB3D KATNB1 SKAP1 MYH7B TTLL6 HAUS4 MYH3 ANK3 NEFH TCHP KRTAP5-9 MYH13 MICAL3 APC2 SCO2 DBNL NAV1 TUBGCP4 SYBU ACKR2 CCDC181 DNAH1 HOOK2 TUBA4B ANK2 TPGS2 NBR1 NOS1 FBN2 CDK5 CTTN TBCB BCAS3 CAMSAP3 CENPE MAP1LC3A SRPRB GOLGA2 ESPN SYNE2 TTC30B DCDC1 PNN KRT80 ENO1 TUBA1C KRT17 MAP9 BFSP2 DNM1L TTLL5 CLASP1 KIF24	up	*
GO_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE	0.0031930	0.0485860	0.4317077	-0.2444098	-1.359919	236	RAMP3 AKAP5 STAC PRKG2 P2RY1 EMP2 RDX RAPGEF2 RAB3C RAMP2 PID1 TTC7B INPP5K BAG4 MYADM PRAM1 VAMP2 SYS1 GAS6 EPB41L3 GGA2 NUMB CNST RAP1A PICALM SPTBN1 WNT3A ROCK2 RAB12 SORBS1 ACSL3 ROCK1 DAB2 STX3 TMBIM1 FCER1G PPP2R5A VAMP5 DCHS1 EFR3A VAMP3 KIF13A NKD2 APPL1 RAB8B RAB31 RHOG PALM STX7 PIK3R1 PRKCE GRASP RAB8A RHOQ EHD2 EPHA3 TGFB1 TSPAN14 CD81 LGALS3 CLASP2 ACTN2 MACF1	down	*
GO_MULTICELLULAR_ORGANISM_REPRODUCTION	0.0030284	0.0473608	0.4317077	0.2729437	1.357557	555	TSPAN8 TRIP13 TP63 BRINP1 SPATA24 SPATA25 MYCBPAP FOXA3 PPP1R1B RUVBL1 PMFBP1 CCNB1 WFDC2 NPAS1 DPY19L2P1 GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 SPP1 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 STC2 CYP27B1 NOX5 APOL2 SPINK1 CIB1 TDRKH MCM8 MAP2K6 SRPK1 RSPH1 ZSCAN2 OSBP2 CASP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A AURKA REC8 ODF2 SYCP2 POC1A DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 EGFR OAZ3 CGB7 HSF2BP OXTR BRIP1 SPAG8 PTGDR2 CCDC136 MEA1 ASF1B LRGUK MERTK PICK1 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 ADNP MTOR CTSV MNS1 ADAM28 IQCG MORN2 UBE2Q1 PCSK4 GAS2 TSSK3 MMP7 TEKT3 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 THRB ESR1 TYRO3 NR6A1 KDM3A PTN MEI1 ROPN1B BCL2L1 CATSPER2 BAD DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 GGT5 ETV6 PHC2 SH3PXD2B PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2	up	*
GO_ANCHORING_JUNCTION	0.0000475	0.0021706	0.5573322	-0.2231540	-1.356900	687	SLC6A4 LIMS2 AJAP1 WTIP ARHGAP31 TEK TSPAN4 PDLIM2 DLC1 PECAM1 RASIP1 KCNA2 CAT LPXN RDX RAPGEF2 CDH5 ENG CD44 TMOD3 CGNL1 STXBP6 DDX6 CAV1 CORO1C MYADM BAIAP2 CDH13 BMPR2 ESAM ADCYAP1R1 CDC42 NEDD9 IL1RL1 VAPA CD9 CBL EPB41L3 SCN5A HSPG2 HEG1 RHOA NUMB ANXA1 PTPRM ADAM17 CSRP1 TMEM204 ITGA5 HSPB1 PARVG ANXA5 FZD4 PCDH12 CAV2 LCP1 DES PPP3CA JAM3 TNS1 LAMTOR3 ARHGEF2 SGCA CNN1 SORBS3 EPB41L2 RHOB PTPN12 AMOTL1 SYNPO AHNAK SDCBP SORBS1 LIMS1 LIN7C YBX3 PLAUR KLF11 DAB2 PARVB VASP TJP1 STX3 CLDN5 CLIC4 CADM1 PTPRC VIM JAM2 FRMD4A ACTR3 CD53 SMAD7 PEAK1 VAMP5 ADD1 MAPRE2 LIN7A ACTR2 HCK PROCR ARHGAP17 KCNA5 FAM107A SLC8A1 SCN4B FLT1 WASF2 SYNPO2 SNAP23 MAGI2 PIKFYVE PDCD6IP AQP3 NOTCH1 LIMD1 RAC2 MAP4K4 HSPA1B RHOG RPL9 JAK1 FERMT2 PODXL PIK3R1 GRB2 CAP1 PDZD2 YWHAZ ITGA11 MCAM FGFR4 CD151 SPRY4 RRAS GJA4 PKD2 PRKCG EPPK1 FLNC MME PARD6A STRN TGFB1I1 PDLIM1 ATP6V0C CNTNAP1 CD81 CLASP2 GNA13 ACTN2 ADAM10 PRICKLE4 ICAM1 PDLIM5 LAT ARPC2 WDR1 EPB41L5 XIRP1 DCTN4 TIAM1 EPHA4 DIXDC1 ARL14EP HSPA8 ACTB HNRNPK EPHA2 RND1 RPS13 PARVA	down	**
GO_REGULATION_OF_BODY_FLUID_LEVELS	0.0004784	0.0131750	0.4984931	-0.2339765	-1.353145	386	CLEC1B EDNRB ADTRP GATA2 F2RL3 ADCY9 P2RY1 EMP2 ADCY4 THBD RCOR1 TRPC3 FYN MMRN1 INPP5K CAV1 TBXA2R FGF10 PRKAR1A CDC42 CD9 GAS6 CYP4A11 HPS5 PEAR1 HEG1 CD36 SH2B3 ADA FOXA2 ENTPD1 CSRP1 HSPB1 ANXA5 SLC7A11 GATA3 NFE2L2 WNT3A PDGFA FLI1 STAT5A ARRB1 DGKE PTPRO PLAUR THBS1 SOCS2 MAFG MPL NPR3 ITPK1 DOCK9 P2RY2 AQP4 SELP AXL HPSE TLR4 CAPZA2 FCER1G PLEK WFS1 GNAQ UBASH3B CYP26B1 PIK3R5 GNAI2 C4BPB MAFF VWF NCOA1 PROCR SRF PRCP METAP1 ADCY2 IL6 AQP3 ENPP4 PIK3R1 PABPC4 PRKCE CREB1 NPR1 PRKACA DOCK8 AP3B1 YWHAZ CD34 PLCG2 EHD2 PRKCG SLC4A5 MYL12A DGKG STXBP3 EHD1 VAV3 TEC NLRP6	down	*
GO_ORGANELLE_LOCALIZATION	0.0018446	0.0336206	0.4550599	0.2721018	1.351458	544	KIF1A CEP72 SPICE1 CPLX2 CEP89 RPGRIP1L AP3B2 PDCD6 NEK2 CCNB1 CENPF UCHL1 C17orf75 NDC80 RAB3IP MKS1 BET1 BRSK1 KIF14 ASPM PCLO MSTO1 COL7A1 CEP70 PLK1 NUF2 CDCA8 CENPA ESPL1 DYNC1I1 CDT1 DCTN2 SPDL1 HAUS5 CEP250 DLG1 KIF23 SYTL2 BOD1 BICD1 COPG2 COPG1 KIF3B BRAT1 FBF1 EXOC4 AURKA ODF2 YKT6 SFI1 KIF2C MAD1L1 CDCA5 GPSM2 BLOC1S1 AP1M2 SLC9A3R1 MAD2L1 KIF3C RAB13 C2CD3 SPRY1 PARD3 MYO1A PSRC1 MARK1 NUSAP1 NSF IQCB1 CDK1 CROCC CLMN CEP97 KIF5A CD300A SNX4 CENPJ AP3D1 ATP2A1 SUN1 SYN3 TCTN2 CDH3 SPAG5 KXD1 SAPCD2 TRAPPC12 FGFR1OP STK11 KPNB1 EIF6 MYO19 CEP63 BBS5 PLEKHM1 PABPC1L CEP192 NPHP1 CDC23 TUBG1 DLGAP5 SEC16B NINL LLGL2 KIF22 DNM1 CENPQ SYT1 S100A13 MEI1 CKAP5 KCNB1 TMEM106B GBF1 TCTN1 AP3M2 PPP6R1 CHMP4C CDK5RAP2 DYNC1LI2 RAB15 HAUS6 RABEPK CLUH LTV1 RAB3D KATNB1 HAUS4 NEFH GOSR2 CEP152 RAB34 NUP62 B9D1 ATP6AP1 ALMS1 SYBU CEP164 VPS33B TRAPPC9 STK25 SEC13 PPFIA3 CHMP1A MARK4 NLGN2 TRAK1 CHMP2A CDK5 TMED9 LLGL1 RHOT2 NTN1 GOSR1 CENPE DTNBP1 GOLGA2 TSNARE1 SYNE2 RASGRP1 RRS1 DNM1L WIPI1 NLGN1 CLASP1 BRSK2 TMEM201 KIF24 PLIN5 TRAPPC6A ESYT3 SNAP25 F5 CEP290 CHMP6 VPS18 DYNC1H1 SPHK2 TFG PLK4 PDZD8 AKAP9 PCNT	up	*
GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT	0.0007385	0.0179909	0.4772708	-0.2323803	-1.350081	438	SIRPB1 CD300LF FOXF1 HMOX1 PPARG GATA2 SFRP4 IL1B P2RY1 RDX RAB3C INSIG1 PCSK9 STXBP6 CAV1 NEDD4L PRAM1 CDH13 VAMP2 MIR27B GAS6 LAMP1 CBL CD22 SLC11A1 FGR NUMB CD36 ANXA1 CNST MCTP1 RAPGEF4 RAP1A CLEC7A RAB33B PICALM PTX3 PPP3CA SIRPA WNT3A ZFYVE16 MAPK8IP1 APOC1 PPP3CC ARRB1 RAB12 PPT1 SDCBP ACSL3 PTAFR REST ROCK1 DAB2 SEC24B PTPRC AXL ARC SFTPD FCER1G RNF139 LYAR GNAI2 TBC1D4 C4BPB BACE1 CPLX1 HCK NCKAP1L TBC1D5 SNX3 SAR1A LRRTM2 IL2RB APPL1 MAGI2 RAB8B PDCD6IP NOTCH1 RAB31 ADRA1A RAC2 RAPGEF1 GRASP RAB8A UNC13B RALB PLCG2 CD151 EHD2 ATG3 PRKCG EPHA3 STXBP3 EHD1 AP1G1 VAMP4 FPR2 MTMR2 PCDH17 LGALS3 ANKRD13A STON1 CLASP2 ACTN2 PLAA SYT11 UNC13D BMP2K ABL2 CHMP3 ARRB2 RAB5A VPS4B	down	*
GO_CELLULAR_RESPONSE_TO_LIPID	0.0003270	0.0096599	0.4984931	-0.2288203	-1.349338	488	SLC6A4 CXCL3 KMO ZNF366 RAMP3 IL1A SASH1 EDNRB SCIMP PPARG ADTRP CD55 IL1B PID1 INSIG1 LPL LY86 CRY2 MYD88 TBXA2R NR3C1 IL1RN TRIB1 CASP9 RHOA BRINP3 CD36 ANXA1 MIR146A SSTR1 ATP2B1 CARD16 TNIP3 FZD4 LITAF FOXP1 EIF4E NR4A1 SIRPA RB1 TRAF6 SFRP1 WNT3A KANK2 HNRNPU PDE4D NODAL IL10 ROCK2 FOXO1 CASP1 PTAFR KLF4 REST ID3 KLF9 DAB2 ARNTL LY96 CCL3 NFKB1 NR1D2 KCNMB1 CXCL2 IRAK2 VIM AXL TLR4 LBH PER1 INHBA CPT1A CYP26B1 IL24 NCOA1 PIAS1 HCK PDK4 UFM1 WNT9A FAM107A CREBRF CD80 ADCY2 IL6 RWDD1 DDX17 CARD8 DNAJA1 PTGER4 IRF8 DDX5 PRKCE CREB1 PTGER2 MALT1 MT-ND3 CXCL5 EGLN2 ADNP2 MAPK8 WNT11 DDX18 HNRNPD EPHA3 TGFB1 NR2C1 CD6 TGFB1I1 GNAI1 CD86 PIM1 PLSCR4 KLRC4-KLRK1 WBP2 CRY1 PLAA PDE4B TSPO RXRA NR2E3 ICAM1 IL18 ABL2 TFPI ARRB2 OSR1 RIPK2 NLRP3 PTCH1 HAVCR2 FDX1 NFKBIA RET EDN1 KLRK1 RORA LDLR NR3C2	down	**
GO_REGULATION_OF_CELL_MORPHOGENESIS	0.0011740	0.0245307	0.4550599	-0.2303510	-1.346284	415	TNR LIMS2 DAB1 SEMA6B SEMA3G SEMA6A WTIP DLC1 FGD5 P2RY1 RDX DPYSL2 RAPGEF2 TRPV2 BDNF FYN SHANK3 CD44 CORO1C MYADM NEDD4L BAIAP2 BMPR2 CDC42EP2 CDC42 NEDD9 EPB41L3 FGR RHOA ZEB2 SEMA6D ANXA1 SEMA3B TTL HECW2 PLXNA2 FZD4 PPP3CA ZMYM6 PLXNA4 ISLR2 NDEL1 CRK WNT3A ITSN2 ATP10A RHOB LRP4 AGO4 PTPRO LIMS1 ZSWIM6 TRIM46 PARVB MPL FMNL3 CCL3 ARC SS18L2 WASF3 ZMPSTE24 PAFAH1B1 RUFY3 ACTR2 HEXB HCK SRF KANK1 FMNL2 PSEN1 RHOBTB2 LIMD1 RAC2 RHOG RHOJ PALM FERMT2 SKIL IFRD1 RTN4R TRAK2 PALMD RHOQ EPB42 ZRANB1 HECW1 GNA13 MACF1 PLAA ADAM10 IST1 UNC13D ICAM1 PDLIM5 ARPC2 WDR1 SEMA4A RTN4 CDC42EP3 TIAM1 CXCR4 EPHA4 ARHGAP18 BRWD1 RND1 ULK2 PARVA SIN3A RET KIT PTEN	down	*
GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS	0.0008501	0.0197861	0.4772708	0.2657830	1.345157	777	CCNO STYK1 HKDC1 EPHB3 AK4 CHEK2 BUB1B MYO3B PPIP5K1 NEK2 XYLB CCNB1 FRK POLQ PBK PGM2L1 GUCY2C PRIM2 NMNAT3 TBRG4 IP6K3 STK36 TTK EFNA3 CDK4 BRSK1 STK31 POLE CNTD2 FLAD1 PLK1 EFNA4 AURKB ALDH18A1 CCL8 PAK6 WNK2 CCNB2 PRKCA CCNF PIP4K2C MAP2K6 SGK2 SRPK1 INSRR EPHB1 AGK AK8 TAMM41 NME1 IKBKE POLR3A MELK DLG1 DYRK1B RPAP1 CARD11 POLM MAP3K13 BUB1 AURKA POLA2 ATR POLD2 COASY PRKDC NME9 PKM SBK1 EIF2AK1 PHKG2 PASK TRPT1 NME5 EGFR POLR3C RIPK4 CHEK1 NEK11 EPHA10 PFKP MST1R KHK AKT2 PKMYT1 DDR1 CAD ERCC2 MNAT1 PIGO DYRK2 MARK1 POLN TNIK IKBKB FGGY DCLK1 TTBK1 TERC CMAS FASTK PAK1 LRGUK CDK1 CDK12 EPHA1 POLE2 PI4KAP1 UCK2 MERTK STK32A TNK2 POLR3K MAP3K10 CCNJL ITPKA KSR2 PDK1 NEK5 POLR1C AK7 PRKAA2 UCKL1 MAST1 ACVR1B STK11 TEP1 ULK1 HYKK NMNAT2 POLR2H ANKK1 CCNE1 TRIM24 CDK3 DCAKD NEK10 NADK2 GALK2 MTOR POLL TRIO PIGG MAPK13 EPHB2 TK1 DTYMK PIPSL CSNK1G1 LMTK2 MAPK10 TSSK3 GK5 CDK13 POLD1 TYRO3 POLB CDC7 IP6K2 RAD50 TNK1 FN3KRP DGKA ERBB3 POLR2J GMPPA CKMT2 CDC42BPG SRPK2 NMNAT1 NEK4 POLR2J3 ADCK1 PIP5K1A PFKFB4 POLR2I LRRK1 POLR3E CCNG1 MAB21L1 MUSK PRKD2 STK39 PI4KA STK35 ROS1 PI4KAP2 PMS2P1 ATP6AP1 MAP3K14 CCNA2 ULK4 PRIM1 STK38 CDC42BPA POLR3B CSNK1G2 NME4 PAK4 CTU1 ICK HK2 STK25 MAP3K9 PFKM MARK4 NME7 CDK5 POMK ERBB2 POLR1B PNKP POLR1A GNE GLYCTK GDPGP1 TSSK4 SEPHS1 EPHB4 NPR2 RIPK3 ADCK2 OAS3 PI4KB TK2 BRSK2 MOK ALPK1 MAP3K19 MAP2K2 ERCC3 PRKAG1 ROR2	up	*
GO_RESPONSE_TO_NITROGEN_COMPOUND	0.0000071	0.0004701	0.6105269	-0.2174413	-1.342549	875	SLC6A4 GPD1 EREG RAMP3 LPIN2 TEK EDNRB PPARG ADTRP GPIHBP1 HHEX CPEB2 IL1B ATXN3 LHCGR CAT ADCY9 P2RY1 ADCY4 RAPGEF2 PTPRE THBD PID1 KL PCSK9 TRPC3 FOLR1 FYN LPL EGR2 PDE1B RGS9 INPP5K CAV1 BAIAP2 FOSL1 AQP9 CDH13 MYD88 VAMP2 C5AR1 PRKAR1A TGFBR3 CD9 RFTN1 RHOA DNAJB14 PDE2A EDEM1 CD36 ANXA1 MIR146A ATP2B1 DNAJC18 RRAGC ADA RAP1A BTG2 ANXA5 KLF10 CAV2 IFNK ADIPOR1 PPP2R2A PPP3CA NR4A1 ADRB2 NFE2L2 NDEL1 LAMTOR3 CRK SFRP1 ZEB1 ARHGEF2 EPM2AIP1 PDE4D ATP6V1H MTHFR TMEM38B ATP6V1B2 FOXC2 IL10 ROCK2 STAT5A RAB12 FOXO1 SGTB SRSF5 BIRC2 SORBS1 RNFT1 PTAFR KLF4 RRM2B ROCK1 KLF11 BCHE SOCS2 ATP6V1D SOCS5 ABCC4 UBQLN1 ATG7 SSH1 NFKB1 CDKN1A PDE3B P2RY2 SIK2 VIM SELL ATP6V0D2 TLR4 FCER1G PER1 DUSP1 RNF139 PIK3C2A WFS1 GNAQ GNAI2 TBC1D4 BACE1 ACTR2 MMP19 GNRH1 BTG1 USP25 SLC25A33 PDK4 KANK1 MYO1C SLC8A1 ADCY2 AREG IL6 PSEN1 SOCS3 APPL1 RAB8B JUN STAT4 NOTCH1 CPEB4 GABPA RAB31 USO1 HRH1 ATP6V0B DUOX1 JUNB PALM RAPGEF1 DHX15 CCR7 PIK3R1 UBAC2 PRKCE GRB2 CREB1 RAB8A PRKACA HOMER1 RALB SLC3A2 FOS ATP6V0D1 RHOQ PELI1 KLF2 CACYBP FOXO3 PKD2 SRSF6 PRKCG TREX1 FOSB MARC2 HNRNPD IRF5 SORT1 STXBP3 PEA15 SRSF4 GLRA3 FPR2 PDE12 GNAI1 ATP6V1A MIA3 PIK3C3 IRS2 ATP6V0C SLC8A3 CD81 GLRA1 BAG6 KYNU CRY1 ACTN2 RGS2 KAT2B PDE4B TSPO JUND ICAM1 SESN1 VGF HTR6 ARRB2 TIAM1 CXCR4 SEC61B EPHA4 RIPK2 NLRP3 ACTB IPO5 MBD5 SREBF2 FDX1 SIN3A NFKBIA MARC1 RAPGEF3 ADORA2A EDN1 PTEN DNAJB9 P2RX1 LDLR CCND3 GRB10 IQGAP1 ATF4 PMAIP1 SMPD1 CYBA EPG5 ATP6V0A1 HERPUD1 KLF15 ACVR1C EGR1 UBR2 GHR CDKN1B CNR2 UBXN8 KCNE1 ZNF106 HMGCS1 NR4A2 MAPK1 CNGA3 ITGB1 TREM2	down	***
GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS	0.0020004	0.0351383	0.4317077	0.2667940	1.342398	664	TSPAN8 SYT8 PRLR TRIP13 TP63 ABCC2 SPATA24 SPATA25 MYCBPAP FOXA3 PPP1R1B RUVBL1 PMFBP1 SPINK13 CCNB1 WFDC2 DPY19L2P1 SLC2A1 CLGN GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 SPP1 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 STC2 CYP27B1 UMPS NOX5 APOL2 SPINK1 CIB1 TDRKH MCM8 SRPK1 CCT2 RSPH1 ITGA2 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A IDO1 CCT5 AURKA AGT REC8 ODF2 SYCP2 POC1A IL12B DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 OAZ3 CGB7 HSF2BP MST1R OXTR BRIP1 DDR1 CAD GNPDA1 SPAG8 PTGDR2 CCDC136 ALDOA MEA1 IGFBP5 ASF1B LRGUK CDK1 MERTK PICK1 CCT3 GOT2 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 ACVR1B STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 MTOR CTSV MNS1 ADAM28 DHODH IQCG MORN2 UBE2Q1 PCSK4 GAS2 TSSK3 SPAG1 MMP7 TEKT3 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 THRB ESR1 TYRO3 CCT7 NR6A1 KDM3A EPN1 PTN MEI1 ROPN1B AAAS BCL2L1 CATSPER2 BAD TFCP2L1 DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 PKDREJ PTHLH GGT5 ETV6 PHC2 SH3PXD2B PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2 ADM	up	*
GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS	0.0009504	0.0214033	0.4772708	-0.2304112	-1.341454	394	SLC24A4 HCRTR1 GPR17 RAMP3 CD52 SWAP70 MCOLN1 EDNRB CD55 GATA2 F2RL3 SNX10 P2RY1 GPR65 CDH5 KL TRPC3 FYN JPH4 CCRL2 CAV1 ADRA1D GTF2I SLC39A8 ADCYAP1R1 TBXA2R C5AR1 S1PR1 SLC11A1 CD36 JPH2 ATP2B1 KCNK3 ANXA5 MS4A1 PDE4D TMEM38B GPR4 SYNPO PTGIR RMDN3 CCL3 PTPRC PTGER3 RAP1GDS1 WFS1 HTT GPR157 UBASH3B CALM2 PLCD1 PTH1R HEXB KCNA5 S1PR4 SLC8A1 PDE6A PSEN1 PDE6B CNNM2 ADRA1A JPH1 GSTO1 PTGER4 CCR7 ACKR3 PRKCE PTGER2 GRIA1 ATP13A3 PRKACA SLC10A7 CLN3 PLCG2 CALM1 PKD2 SYPL2 CCR4 FPR2 MCUR1 SLC24A1 SLC8A3 CCR1 NPTN GNA13 GPR18 CALB1 CCR6 FGF2 ABL2 FKBP1A SLC24A5 TPT1 CXCR4 CCR9 MT1M BOK CD19 EDN1 MCOLN2 P2RX1 MT2A LPAR6 ATF4 CYBA HERPUD1 C5AR2 FKBP1B CX3CR1 S100A8 FPR1 ATP1B1 PIK3CG MT1E CALR BDKRB2 FPR3 TRPM7 WNT5A PLN GPR55 HMGB1	down	*
GO_OTHER_ORGANISM_PART	0.0013540	0.0270100	0.4550599	0.9990714	1.333090	1	LTF	up	*
GO_MOTOR_LEARNING	0.0020099	0.0352387	0.4317077	0.9987619	1.332677	1	DKK1	up	*
GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY	0.0009234	0.0210278	0.4772708	0.2617997	1.326766	795	PRLR SCIN FGA HELLS HJURP RUVBL1 CDC45 NUP107 BAIAP2L2 COIL CENPF CPSF6 COA1 AVIL PRRT2 CABIN1 TSPYL5 ANLN NDUFS6 BAIAP2L1 CENPA ACAD9 SOX9 MCM4 MCM2 EFNA5 EIF3B MIS18A ARHGAP40 CAND1 SRPK1 VILL CDT1 CCT2 UQCC1 MICALL2 DNAI1 PPP1R9A RUVBL2 ARMC4 NDUFB8 DLG1 NLE1 CHAF1A WASF1 CENPL SPTB NDUFS2 ATR FGG MCM7 CENPW TEKT2 ZNHIT6 ERAL1 CCDC114 PCDHGA3 FHOD3 MCM3 CHAF1B PFN2 ANG PSMG4 DNAH8 CDC42EP1 PSMD4 CENPO COX19 CLIP3 PIH1D1 DNAAF3 MRPS11 GEMIN7 NOL3 ERCC2 TRPV4 MNAT1 CCDC40 PARP1 PSRC1 GEMIN4 TTBK1 DRC1 ASF1B PAK1 LRRC6 CENPJ CENPH ARPC1A PICK1 GMNN ERC2 ALDOB PRPF6 ACTR3C DHX33 NUP205 ACTR3B EGF TAF6 COA4 TRAPPC12 SNRPE DNAH5 UQCC2 NOP2 PSMC4 DIAPH3 CENPP GBP5 EIF6 VBP1 TAPBP CEP192 TUBG1 NDUFA11 TAPBPL COA3 VPS41 DNAH7 FOXRED1 CCL21 MTOR TRIM9 LONP1 CCDC151 MRPL11 HIRA SPTBN5 COPS7B ADAR DBN1 CENPQ MSRB2 HIP1R SPTBN2 GEMIN5 VIL1 CLTA SPAG1 NDUFA13 PRMT7 TM9SF4 COG4 TWF1 ESR1 COX10 CLTB CENPK BAZ2A GEMIN6 CENPV C15orf62 CKAP5 HNF1B CENPM TUBG2 RPA1 WNT10B CDK5RAP2 CLINT1 MCM6 TBCA CELF4 CENPT SRPK2 FCHSD1 MCM5 DNAI2 CD2BP2 SNRPD1 DDX23 SNAP47 EIF3D ADD3 SRSF1 HAX1 CHRNA3 NDUFS7 LSM4 TXNL4A SF3A2 EIF3K PRMT5 NDUFV1 AP2S1 PRPF18 SMARCA4 SCO2 DBNL SNRPD2 DENR TUBGCP4 USP39 WDR77 PRPF31 DNAH1 RAD51 FMOD GTF3C5 SOX12 NDUFA8 SNRNP200 CHMP2A NDUFS8 CTTN NUBPL SNUPN TARBP2 XPC CAMSAP3 CENPE EIF4G1 ADRM1 SWI5 TP53 PRPF3 GOLGA2 ALOX15 SNRPC UBE2C MSRB1 UBTF MRPL20 SART1 ZMYND10 SMARCB1 ATF7IP DDB2 NDUFB7 RRS1 DNM1L IMMP2L CLASP1 NUP93 COX17 SART3 BRIX1 RANGRF CORO1B ERCC3 GEMIN2 SNAP25 PMEPA1 CLNS1A POGZ NDUFAF6 EIF2D RPL23A VPS18 EID2 MRTO4 DNAAF1 LUC7L3 DRG1 SHQ1 VPS16 WDR63 AXIN1 PRPF19 AKAP9	up	*
GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION	0.0011199	0.0238937	0.4550599	-0.2254541	-1.318358	420	RTKN2 SEMA6A WTIP OTUD7A DLC1 RASIP1 IL1B FBP1 CD44 CGNL1 INPP5K CAV1 MYADM TBC1D7 PLEKHA1 HMGCR DYRK1A USP47 CD22 HEG1 PPM1N RHOA PDE2A WWC2 MIR146A MYOZ1 SH2B3 TNIP3 HSPB1 RANBP9 RNF125 LITAF HIPK3 PAQR3 ADIPOR1 SIRPA NFE2L2 SFRP1 SPRY2 ARHGEF2 MAPK8IP1 PDE4D MCL1 ARRB1 SNAI1 DUSP3 FOXO1 YBX3 KLF4 PLAUR RRM2B THBS1 ARNTL EPM2A PDE3B PTPRC ATF3 TLR4 UBE2B TAF9 PER1 DUSP1 PLEK PINK1 PPP2R5C WFS1 PAFAH1B1 GNAI2 CALM2 MARK3 TGFB2 KANK1 PPP2CA RNF149 MAGI2 SEC14L1 LIMD1 ADRA1A CARD8 DNAJA1 DUSP8 RCAN1 RAPGEF1 GSTO1 BAG5 ACKR3 RASSF2 RRN3 SPRY4 CALM1 PKD2 CD74 PPP2CB TIMP2 KCTD10 NLRP6 DUSP5 SOD2 RGS2 PHLPP2 SESN1 ABL2 ARRB2 TPT1 PP2D1 NLRP3 GPD1L EPHA2 ING2 CUL3 TIMP3 SCAI FNIP2 PTEN DUSP7 RORA ITCH MAPKAP1 SMAD4 BANK1 SMPD1 HERPUD1 HTRA2 CHP1 UBR2	down	*
GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS	0.0019215	0.0343439	0.4550599	-0.2264670	-1.317829	366	GPD1 TRIM71 HMOX1 ABHD5 IL1B ATXN3 RDX PCSK9 ECSCR SOX17 CAV1 NEDD4L PAFAH1B2 TRIB1 RCHY1 EDEM1 FBXO7 RILP HECW2 BTG2 RNF144B FAM122A ADRB2 NFE2L2 ZYG11B TIPARP FBXL5 ROCK2 RAB12 FOXO1 MEFV TNFSF12 RNFT1 ROCK1 DAB2 CEBPA SOCS5 EPM2A UBQLN1 ATG7 C9orf72 RNF139 SMAD7 CPT1A PINK1 HTT C4BPB CNOT6L PIAS1 MYLIP IL6 PSEN1 NKD2 HSPA1B PLK3 PRKCE STX5 RC3H1 SNX1 UVRAG EGLN2 RALB SNX9 GRSF1 PNPLA2 YTHDF3 FOXO3 HNRNPD TFEB SMCR8 METTL14 HECW1 YTHDF2 CBFA2T3 ZC3H12D IRS2 CNOT7 CD81 BAG6 TOB1 HACE1 BNIP3L SESN1 PIP4K2A HSP90AA1 CALCOCO2 RIPK2 ARIH1 ULK2 DAPK1 CTSC PTEN ITCH LDLR CNOT8 ZFAND2A PUM1	down	*
GO_MITOCHONDRION	0.0002313	0.0076261	0.5188481	0.2554618	1.314583	1268	CPS1 PPM1H TP63 HKDC1 BBOX1 PTGES BIK HJURP AK4 CEP89 BDH1 GPT2 EYA2 CCNB1 GPAT2 FLVCR1 COA1 CHCHD6 DDIT4 TSFM SLC25A21 PIF1 NMNAT3 SORD IFI27L1 TBRG4 THEM4 CREB3L4 THEM5 MRPL46 ANKZF1 NIPSNAP1 MSTO1 NDUFS6 FLAD1 TOMM34 ACAD9 ALDH18A1 SFXN1 TFDP2 NNT PRKCA CYP27B1 TYMS GLDC TDRKH LIG3 COX6B2 SHMT2 MRPS35 COQ3 COX11 AGK UQCC1 TAMM41 NME1 IKBKE AARS2 CASP2 NOS1AP NDUFB8 NUDT1 CISD1 GOLPH3 XPNPEP3 SDHA QTRT1 MRPL15 PCCB CYP24A1 GPER1 BPHL NDUFS2 PSENEN TMEM177 YKT6 GTPBP3 LARS2 COASY GCAT AKAP1 AMACR ERAL1 MRPL3 PKM MRPL27 BLOC1S1 MCCC2 SOX4 PYCR2 TARS2 FAM162A LETMD1 LIG1 BRI3BP SARS2 HEBP2 ABCB6 ASS1 TRMT61B ACSF2 COX19 SLC25A39 DCTPP1 TIMM50 KCNJ11 MRPS11 PERP ETFA FDXR MRPS30 MTG1 PHB TST NOL3 ATAD3C IDH2 SLC25A10 UQCR11 COQ9 TRIT1 PARP1 THOP1 PON2 GCKR MRPL36 FASTK HARS2 URI1 MRPL37 PPM1E CDK1 SSBP1 PICK1 ATP2A1 CCM2 NUDT2 DMGDH GOT2 ZMIZ2 OAT E2F1 ACP6 UNG TRAP1 TMEM8B L2HGDH MCAT DNA2 DGAT2 MRPS2 SLC25A13 MRPL17 POU5F1B ACSBG2 PDK1 FEN1 MECR COA4 MRPS12 TNRC18 LIPT2 ETFB ATAD3A NLN UQCC2 CPT1B STK11 CHCHD3 NRGN ULK1 CHCHD2 HYKK MYO19 PARS2 FANCG IFI27L2 UQCRFS1 GNPAT DLGAP5 ATP7B NADK2 NDUFA11 NFS1 SPG7 COA3 FOXRED1 SPATA18 TRMU MTOR DNAJA3 PUS1 ALDH7A1 FHIT ADAM28 SLC25A18 UROS MRPS34 LONP1 DHODH PTGES2 C19orf12 MRPL11 MRPL52 COX7C PPOX DTYMK MSRB2 HIP1R MRPL4 ACAD10 AGPAT5 MAPK10 DAP3 ENOSF1 TMEM186 DNAJC11 NDUFA13 GFM2 GSTK1 GK5 ACSL6 JTB COX10 PARP9 NAIF1 ELAC2 NT5M YARS2 NIF3L1 DHTKD1 KLC2 CHPF P4HA1 NAGS C15orf62 TIMM13 BRD8 STOML2 IARS2 CHCHD1 SIRT4 GBF1 C12orf65 LRRC59 FAHD1 MRPS23 BCL2L1 BAD NAT8L NOL6 PHYKPL MRPL24 MGME1 MRPS33 CKMT2 MRPL28 MRPL41 HIBADH ROMO1 CAPRIN2 HEATR1 ACOT11 SIRT5 MALSU1 TFAP4 MRPL53 HAX1 PRODH CYP2D6 NDUFS7 AMT MRPL51 LRRK1 SUOX TCHP PLEKHN1 DOK7 NDUFV1 PYCR1 MRPL14 AGMAT ME1 SCO2 DCPS CISD3 ECH1 MLXIP VDAC1 MRPS25 PDF MRPL55 NME4 CDK5RAP1 ABHD10 UQCRC1 LPIN1 ACSF3 HK2 ANK2 RAD51 HLCS GADD45GIP1 CAPN10 NBR1 MTIF3 TOMM40L COX5B SLC25A29 ATG4D NOS1 MCU OXCT1 RSAD1 ECHS1 ZNF217 MRPL9 TRAK1 MRPL21 AIFM2 MICU1 NDUFA8 NDUFS8 RHOT2 METAP1D NUBPL CPOX ETHE1 AURKAIP1 VDAC3 UQCRQ CIAPIN1 PNKP CPT1C PARG XPC PFDN4 EARS2 MPG GLYCTK ZNF205 MTHFD1 TP53 NMT1 TRUB1 TIMM44 FIS1 APEX1 SYNE2 MRPS27 GPN1 PDP1 ARMC10 SFXN4 BCAT2 SFXN5 MRPL20 RIPK3 MRPL48 PI4KB NDUFB7 COX6B1 DNM1L TK2 MRPS26 IMMP2L GSDMC TRUB2 PLIN5 COX17 ACAD8 HEMK1 CYP11A1 MTG2 C12orf10 MAP2K2 ACSL5 CYB5B RPUSD3 TFB1M SARDH BCKDK TOMM7 RTN4IP1 NDUFAF6 POLRMT TNFRSF1A SFXN2 BMF MRPS16 ACSM3 UCP3 DGUOK SPHK2 TOP3A PDK2 GSK3A PPARGC1B PDZD8 MRPL12 CRAT NIT1 PARL GSTP1 CLPP SRI MRPL43 SDHAF1 FASTKD3 OPA1 RSAD2 BAK1 MRPL2 TOMM40 MCEE TIMM10 GLRX5 COQ5 MPST TEFM PGAM5 GCSH XAF1 MRPS6 DHRS4 D2HGDH DHX32 STXBP1 ABCD3 HINT2 MARS2 CS NDUFB2 TXN2 TPPP CMPK2 PC LRPPRC COX15 TIMM9 MCCC1 DYNLT1 PPP2R1A MTHFD2 BOLA3 CALM3 BNIP1 TMEM102 COX6A1 METTL17 SLC44A1 SLC25A35 FIBP COQ4 TFAP2C CAPN1 NDUFA4L2 TMEM14A BECN1 COA6 PNPLA7 MIEF1 NDRG4 ACOT7 COX6C ECHDC2 ABCB8 PTCD2 IDE NDUFA9 GRAMD4 SDHC RNASEL SLC27A1 WDR93 MRPS7 CHCHD5 ACADS MRPL35 MRPL13 DARS2 STPG1 TXNRD3 DHX30 GATM CLPB NOD2 PDSS2 CNR1 MRPL33 GCLC GSR DNAJC5 NDUFA10	up	**
GO_ENDOSOME_MEMBRANE	0.0020277	0.0353681	0.4317077	-0.2246115	-1.307947	400	SLC6A4 MCOLN1 OSBPL11 TMEM150B SNX10 DCSTAMP HSD17B6 PCSK9 FIG4 PLEKHF2 CAV1 CORO1C MYD88 ARL8B CD1C LAMP1 SLC11A1 GGA2 ANXA1 SPG21 RILP CHMP1B ZDHHC2 LITAF CYB561A3 ABHD6 ADRB2 TRAF6 LAMTOR3 WNT3A ZFYVE16 UBE2D3 TFRC RAB14 RHOB RAB12 ITM2B CDIP1 MVB12B MYO1B LY96 CTSD TMBIM1 IRAK2 AQP4 ATP6V0D2 TLR4 ARC PLEKHB2 EPS15 TM9SF2 HLA-DQA1 BACE1 CMTM6 TBC1D5 SNX3 TMEM9B CD8B VAMP3 VPS37A GPR61 KIF13A PSEN1 INPP5B APPL1 RAB8B PIKFYVE RAB31 OSBPL9 ATP6V0B VPS26A SNX2 STX7 EEA1 RAB8A SNX1 GRIA1 APH1B ATP6V0D1 UBB CD164 EHD2 SORT1 EHD1 CD1D ZFYVE9 SBF2 MTMR2 ATP6V0C FCGRT STX12 VPS39 CLCN6 LDLRAD4 CHMP3 PARM1 RAB5A ACAP2 VPS4B EPHA4 TAB2 GIMAP5 BOK STAM2 RET MCOLN2 MMD ITCH LDLR EHD4 RNF13 EHD3 SPHK1 RABGEF1 ATP6V0A1 UBAP1	down	*
GO_VESICLE_MEMBRANE	0.0009334	0.0211130	0.4772708	-0.2154189	-1.307811	626	SIRPB1 RAB11FIP1 EREG OLR1 MCOLN1 PECAM1 HVCN1 CD55 WNT4 RAB44 CLEC12A IZUMO1 RAB3C PTPRB FOLR1 CD44 CAV1 VAMP2 C5AR1 MARCO MANBA VAPA CD9 LAMP1 SLC11A1 SCARF1 LILRB3 RHOA CD36 ANXA1 SLC44A2 MCTP1 HBEGF CD33 RILP RAP1A PICALM FZD4 SPIRE1 ANPEP CAV2 STOM LAIR1 SIRPA ADRB2 CD93 LAMTOR3 WNT3A TFRC RAB14 CD58 MSR1 FABP5 ARRB1 MPEG1 NOSTRIN BST1 PTAFR PLAUR DAB2 GAA STX3 ATP6V1D CLIC4 ABCC4 SEC24B TMBIM1 ITGAX PTPRC EPGN SELL SELP ATP6V0D2 M6PR CD53 FCER1G EPS15 WFS1 HTT VAMP5 IL7R PEF1 HLA-DQA1 DEGS1 ANXA3 BACE1 SEC31A CMTM6 HGSNAT RAB6A NCKAP1L TBC1D5 PRCP MYO1C VAMP3 AREG SAR1A PSEN1 PHACTR2 INPP5B SNAP23 APPL1 RAB8B PIKFYVE CYB5R1 NECAP1 SH3BP5 RAB31 USO1 RAC2 ATP6V0B TYROBP ATP11A RHOG RAPGEF1 ENPP4 GLIPR1 GRB2 RAB8A STX5 SERPINB6 GRIA1 UNC13B AP3B1 SNX22 GPRC5A SNX9 ATP6V0D1 UBB MFSD10 PKD2 ALDH3B1 CD74 CR1 SYPL2 MME SORT1 SIGLEC14 TMX3 AP1G1 DOK3 VAMP4 FPR2 TSPAN14 PIK3C3 DYNC1LI1 ATP6V0C GPR84 APLP2 LGALS3 GABARAPL1 BRI3 STX12 GPR18	down	*
GO_SUPRAMOLECULAR_COMPLEX	0.0013764	0.0273495	0.4550599	0.2553002	1.301032	943	KIF1A SAA1 KIF12 KLC3 MEX3A KIF20A MYBPH MDM1 HJURP KRT5 PKP2 DNAH2 RPGRIP1L BUB1B NUP107 NEK2 CCNB1 CENPF TNNI1 KIF18B PKP1 COL27A1 SLC2A1 NDC80 TUBB2B TTK RACGAP1 GTSE1 KIF14 SPAG17 ASPM COL7A1 PLK1 NUF2 KRT16 AURKB CENPA TPX2 CMYA5 DNAH3 PMS2 PRC1 GRB7 PLS1 DYNC1I1 TDRKH CCT6A KIF27 ZWINT MYL6B CDT1 CDK5RAP3 KRT15 DNAH14 CCT2 DCTN2 SPDL1 NME1 MICALL2 DNAI1 HAUS5 RSPH1 TTLL4 TNNT2 NOS1AP DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 TP53BP1 KNTC1 KIF3B BUB1 FBF1 IDO1 MAP10 MYBPC2 CCT5 GPER1 AURKA REC8 ODF2 TPR FLG KIF2C MAD1L1 CD2AP CENPW MAP1LC3C TEKT2 FSD1 NSUN2 HOOK1 DCDC2 FHOD3 KIF11 LMNB1 DNAH8 MAD2L1 NEB CENPO GAS8 KIF3C SPC24 DNAH11 SYMPK FLNB CNOT3 ALDOA TRPV4 PARD3 MYO1A BTBD2 PSRC1 INCENP KNSTRN MYOT NUSAP1 CBX5 PAK1 KRT18 CDK1 DNAH6 KIF5A CENPJ CENPH BIRC5 CCT3 TTLL9 JAKMIP1 DIS3L2 SCTR TNNI2 KIF19 SPAG6 KIF2A NARF KIF7 LARP1 COL3A1 DYNLL2 SPAG5 TRAPPC12 MTBP DNAH5 PRKAA2 KLHL22 SNCAIP KPNB1 EIF6 RANGAP1 UPP2 MOV10 PABPC1L COL1A1 TUBG1 COL1A2 DNAH7 CNOT2 DNAJA3 NINL LMNB2 MNS1 TUBB2A TUBA3D KIF22 KY COL5A2 DNM1 DBN1 TUBA8 CENPQ SCN8A KIF21A GAS2 HID1 MAP6D1 KIF20B LRWD1 TRIM32 SMTNL1 KRT19 FHL2 AHNAK2 TWF1 NUP85 POLB CCT7 CENPK COL11A1 KLC2 KLC4 CENPV CKAP5 ABCC9 CENPM TUBG2 TTLL3 FBXO22 CDK5RAP2 KRT8 DYNC1LI2 KIF21B EML6 TBCA CENPT CKAP2 COL5A3 DNAI2 KPTN ANKRD1 HAUS6 DYNC2H1 FAM161A HAX1 RAB3D KATNB1 SKAP1 MYH7B TTLL6 HAUS4 LSM4 MYH3 ANK3 NEFH TCHP KRTAP5-9 CKAP4 MYH13 MICAL3 APC2 SCO2 DCPS DBNL NAV1 TUBGCP4 SYBU ACKR2 CCDC181 DNAH1 HOOK2 TUBA4B ANK2 CARHSP1 TPGS2 NBR1 ZWILCH SEC13 NOS1 FBN2	up	*
GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION	0.0000400	0.0019109	0.5573322	-0.2133972	-1.300436	822	FFAR4 RTKN2 HCRTR1 GPR17 EREG RAMP3 IL1A SASH1 HMOX1 TEK SCIMP GLIPR2 IL1B C18orf32 F2RL3 CAT P2RY1 GPR65 RAPGEF2 BMPER BMP2 ENG KL FYN CD44 CCL3L1 BAG4 CAV1 CDH13 MYD88 ADCYAP1R1 C5AR1 HMGCR FGF10 CDC42 MIR27B MARCO VAPA IL1RN GAS6 CBL IL23A FGR RHOA ZEB2 AVPI1 CD36 JPH2 SLC44A2 RRAGC CARD16 HBEGF ADA RAP1A RASGRP4 MAP3K8 FZD4 LITAF CAV2 CAMTA1 GATA3 ADRB2 IL18R1 TRAF6 LAMTOR3 CRK SPRY2 MAPK8IP1 TCF7L2 TXN MCL1 PDGFA NODAL SORBS3 GPR4 MAP2K3 ROCK2 ARRB1 CCL22 AGO3 BIRC2 EPOR SDCBP NPNT CASP1 LIMS1 SLC46A2 ROCK1 TNFSF15 THBS1 SPAG9 PDE8A CCL3 PTPRC EPGN IRAK2 SELP AXL HPSE CCL4 TLR4 MIR24-2 XCL2 PINK1 HTT PIK3R5 BCLAF1 GNAI2 CALM2 MAPRE2 SIAH1 TGFB2 TMEM9B ARL6IP5 PRKRA CD80 FLT1 AREG IL6 DNAJC27 GPR61 PSEN1 HCST JUN NOTCH1 ZFP91 ADRA1A HIC1 PDE5A RAC2 MAP4K4 HSPA1B RHOG SHOC2 RAPGEF1 GSTO1 CCR7 SKIL PIK3R1 ACKR3 DDX5 PRKCE GRB2 GPR183 OSM MALT1 NPR1 RC3H1 RTN4R REL TNFRSF10B RASSF2 NDST1 FGFR4 GPR37L1 UBB PELI1 LMCD1 CALM1 KLB PKD2 CD74 WNT11 PIK3AP1 SPOP TIMP2 TGFB1 PEA15 SMCR8 FPR2 MIR23A SH3RF3 DUSP5 CD86 IRS2 MAP3K2 RELL1 TERF2IP CD81 NQO2 CCR1 NPTN GPR18 SERINC3 CCL20 ICAM1 FGF2 IL18 MIER1 FKBP1A HTR6 ARRB2 RTN4 TIAM1 CXCR4 HSP90AA1 EPHA4 TAB2 RIPK2 SIK3 HAVCR2 S100A4 BOK MAP3K4 CD19 RET COPS8 KIT EDN1 PTEN DUSP7 SYNPO2L FGFR1 NRG1 NR3C2 IQGAP1 LPAR6 SFPQ PUM1 RNF13 BANK1 FLT4 PMAIP1 SPHK1 UBE2V1 GREM1 CDON C5AR2 GHR DUSP6 CX3CR1 C5 MAPK1 ICOS ITGB1 TREM2 NCF1 RB1CC1 S100A8 FPR1 NDFIP1 PIK3CG CALR MUL1 IFIT5 WNT5A LAMTOR5 UBE3A MAP4K2 UBE2N KIDINS220 BCL10 TRIM13 AKAP12 GPR55 HMGB1 DDX21 PDE6G EP300 CD3E	down	**
GO_NEGATIVE_REGULATION_OF_CELL_DEATH	0.0001039	0.0039751	0.5384341	-0.2116042	-1.290912	776	FFAR4 PTCRA SMAD6 LIMS2 ANGPT4 RTKN2 IL1A HMOX1 TEK EDNRB SGK3 TBX3 GATA2 IL1B CAT WNT4 RAMP2 BDNF FYN CD44 BAG4 CAV1 CITED2 MYD88 ADCYAP1R1 C5AR1 HMGCR APIP FGF10 BCL2A1 GAS6 CBL USP47 RHOA ANXA1 ARHGAP10 MIR146A CLCF1 DNAJC3 FBXO7 CARD16 ADA LMNA MTRNR2L8 ITGA5 BTG2 HSPB1 RNF144B ANXA5 FOXP1 HIPK3 BFAR SLC7A11 SERPINB9 GATA3 RB1 TRAF6 NFE2L2 GRN SFRP1 SPRY2 WNT3A KANK2 ARHGEF2 MAPK8IP1 TCF7L2 TXN BAG1 MCL1 FOXC2 EVI2B IL10 AGO4 MTRNR2L3 ARRB1 SNAI1 ITPRIP PPT1 FOXO1 BIRC2 BNIP2 SLC46A2 AGR3 YBX3 KLF4 PLAUR NES HYPK REST RRM2B ROCK1 DAB2 THBS1 SOCS2 GRK5 ATG7 TMBIM1 PDE8A NFKB1 CDKN1A AXL MIR24-2 CCND2 UBE2B TAF9 FCER1G DUSP1 PINK1 WFS1 HTT IL7R GNAI2 MIR17HG PIAS1 GNRH1 HCK TOPORS CLN8 NCKAP1L PDK4 UFM1 WNT9A CNTF IL6 PSEN1 SOCS3 IL2RB NDNF JUN MITF NOTCH1 CPEB4 MAP4K4 HSPA1B PLK3 DNAJA1 APBB2 BAG5 CCR7 PIK3R1 ACKR3 CREB1 MALT1 RPS6KA1 REL DOCK8 YWHAZ TNFRSF10B CLN3 CD34 PLCG2 GPR37L1 RRN3 ADNP2 UBB PELI1 CACYBP SRSF6 PRKCG MAPK8 CD74 NAA16 WNT11 ZFAND6	down	**
GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION	0.0031029	0.0477205	0.4317077	-0.2232274	-1.288986	387	SMAD6 SEMA6A RASIP1 HHEX IL1B FABP4 FBP1 PID1 ENG INPP5K CAV1 CORO1C MYADM CTDSP1 HMGCR PRKAR1A CBL TRIB1 HEG1 RHOA MIR146A SH2B3 DNAJC3 FBXO7 FOXA2 LATS2 PPP1R15B HSPB1 RANBP9 HIPK3 PAQR3 SIRPA RB1 SFRP1 SPRY2 HNRNPU MAPK8IP1 PDE4D ADARB1 ARRB1 ITPRIP DUSP3 FOXO1 KLF4 CEBPA SOCS5 CDKN1A PTPRC ATF3 C9orf72 TLR4 MIR24-2 UBE2B PER1 DUSP1 SMAD7 INHBA PINK1 PPP2R5A GNAQ UBASH3B PAFAH1B1 CALM2 PKIG PPP2CA RNF149 PSEN1 SOCS3 JUN SH3BP5 DNAJA1 DUSP8 RAPGEF1 IPO7 GMFG RASSF2 GPRC5A PPM1F SPRY4 CALM1 PKIA CHORDC1 TGFB1 PARD6A SMCR8 PDE12 NLRP6 DUSP5 CBFA2T3 IRS2 TERF2IP MYOCD RGS2 KAT2B DBNDD2 ANKLE2 LDLRAD4 ARRB2 PP2D1 CDKN1C IPO5 GPD1L ADORA2A TIMP3 PAK2 PTEN DUSP7 SAMSN1 ITCH	down	*
GO_POSITIVE_REGULATION_OF_MAPK_CASCADE	0.0020580	0.0356507	0.4317077	-0.2208115	-1.285075	426	FFAR4 HCRTR1 RAMP3 IL1A SASH1 TEK SCIMP GLIPR2 IL1B P2RY1 RAPGEF2 BMPER BMP2 KL CD44 CCL3L1 C5AR1 HMGCR FGF10 CDC42 MIR27B MARCO IL1RN GAS6 ZEB2 AVPI1 CD36 RAP1A MAP3K8 FZD4 CAV2 ADRB2 TRAF6 LAMTOR3 CRK SPRY2 MAPK8IP1 PDGFA NODAL SORBS3 MAP2K3 ROCK2 ARRB1 CCL22 SDCBP NPNT ROCK1 THBS1 SPAG9 PDE8A CCL3 PTPRC EPGN IRAK2 CCL4 TLR4 MIR24-2 XCL2 PIK3R5 GNAI2 TGFB2 ARL6IP5 FLT1 IL6 DNAJC27 PSEN1 JUN NOTCH1 ADRA1A PDE5A RAPGEF1 CCR7 ACKR3 PRKCE GPR183 OSM RASSF2 NDST1 FGFR4 GPR37L1 UBB KLB CD74 TIMP2 TGFB1 PEA15 FPR2 MIR23A SH3RF3 DUSP5 MAP3K2 RELL1 CD81 NQO2 CCR1 NPTN CCL20 ICAM1 FGF2 ARRB2 TIAM1 CXCR4 EPHA4 TAB2 RIPK2 HAVCR2 MAP3K4 RET KIT EDN1 PTEN DUSP7 FGFR1 NRG1 IQGAP1 BANK1 FLT4 SPHK1 UBE2V1 CDON C5AR2 GHR DUSP6 C5 MAPK1 TREM2 NCF1 RB1CC1 FPR1 PIK3CG MUL1 WNT5A MAP4K2 UBE2N KIDINS220 AKAP12 GPR55 HMGB1 PDE6G	down	*
GO_POSITIVE_REGULATION_OF_TRANSPORT	0.0002608	0.0082327	0.4984931	-0.2095448	-1.278544	766	SLC6A4 SIRPB1 RBP4 KMO CD300LF RAMP3 IL17RB IL1A STAC FCN1 EDNRB PPARG GATA2 SFRP4 IL1B F2RL3 SLC51B P2RY1 RDX PLA2G10 TRPV2 PCSK9 TRPC3 FYN LPL SHANK3 HCAR2 RGS9 INPP5K CAV1 NEDD4L VAMP2 ADCYAP1R1 MEF2A CDC42 IL1RL1 GAS6 LAMP1 CBL CYP4A11 SLC11A1 SCN5A ABCB1 FGR EDEM1 CD36 JPH2 ANXA1 CNST ATP2B1 CD33 RAP1A CLEC7A ABCG1 PTX3 STOM GATA3 PPP3CA SIRPA RGCC ADRB2 NFE2L2 SPTBN1 PPP1R13B CRTAM WNT3A MAPK8IP1 TCF7L2 UBE2D3 CD58 PPP3CC IL10 ARRB1 PPT1 SCP2 SDCBP SORBS1 CASP1 TRIM46 TACR2 ACSL3 PTAFR DAB2 MYRIP CCL3 CADM1 P2RY2 PTPRC KCNMB1 AXL CCL4 TLR4 ARC FRMD4A SFTPD FCER1G LYAR INHBA CLEC9A ADIPOR2 PINK1 WFS1 HTT GNAI2 RUFY3 TP53BP2 CALM2 TGFB2 NCKAP1L TBC1D5 MYO1C SCN4B IL6 SAR1A CD160 SGK1 CTSS PSEN1 IL2RB APPL1 MAGI2 RAB8B PDCD6IP RAB31 GLUD1 RAC2 CARD8 PLK3 IFNGR1 RAPGEF1 GSTO1 PTGER4 PIK3R1 PRKCE CREB1 OSM NPR1 UNC13B RBM22 PRKACA HOMER1 YWHAZ CD34 PLCG2 CD151 RHOQ CALM1 MBP EHD2 PKD2 MAPK8 CHIA AZIN1 TGFB1 EHD1 PARD6A AP1G1 FPR2 MTMR2 KHDRBS1 APBB1 IRS2 PPP3R1 CD81 LGALS3 EXOC1 ORM2 CCR1 CLASP2 ACTN2 PLAA CSNK2A2 PPID TSPO ARPP19 UNC13D HSPA2 PCM1 ARRB2 RAB5A VPS4B RIPK2 NLRP3 PTCH1 ACTB HAVCR2 IPO5 GPD1L HNRNPK BOK CD19 SREBF2 GLUL NFKBIA RAPGEF3 ADORA2A RAB2B EDN1	down	**
GO_METAL_ION_HOMEOSTASIS	0.0031004	0.0477205	0.4317077	-0.2152523	-1.275035	504	SLC24A4 EPAS1 HCRTR1 GPR17 SLC31A2 RAMP3 CD52 HMOX1 SWAP70 SLC12A6 MCOLN1 EDNRB CD55 GATA2 F2RL3 SNX10 P2RY1 GPR65 CDH5 KL TRPC3 FYN JPH4 CCRL2 CAV1 NEDD4L ADRA1D GTF2I SLC39A8 ADCYAP1R1 TBXA2R C5AR1 S1PR1 CYP4A11 SLC11A1 CD36 JPH2 TMPRSS6 ATP2B1 KCNK3 ABCG2 PICALM ANXA5 MS4A1 SLC25A37 PDE4D TFRC TMEM38B FBXL5 GPR4 CYBRD1 SYNPO PTGIR KCNMA1 SLC12A4 SLC7A8 RMDN3 CCL3 PTPRC PTGER3 RAP1GDS1 WFS1 HTT GPR157 UBASH3B GNAI2 CALM2 PLCD1 PTH1R HEXB KCNA5 S1PR4 SLC8A1 PDE6A PSEN1 PDE6B CNNM2 ADRA1A JPH1 GSTO1 PTGER4 CCR7 ACKR3 PRKCE PTGER2 NPR1 GRIA1 ATP13A3 PRKACA SLC10A7 CLN3 PLCG2 ATP6V0D1 CALM1 PKD2 SYPL2 CCR4 EPB42 FPR2 ATP6V1A MCUR1 SLC24A1 SLC8A3 CCR1 SCARA5 NPTN GNA13 GPR18 CALB1 CCR6 FGF2 ABL2 FKBP1A SLC31A1 SCN7A SLC24A5 TPT1 CXCR4 CCR9 MT1M ISCU BOK CD19 ADORA2A EDN1 MCOLN2 P2RX1 MT2A LPAR6 ATF4 SMAD4	down	*
GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS	0.0002951	0.0089700	0.4984931	-0.2068123	-1.274191	885	GPD1 FFAR4 ANGPT4 DAB1 HCRTR1 EREG RAMP3 ACVRL1 IL1A SASH1 TEK ACE DLC1 EDNRB SCIMP TAL1 PECAM1 ADTRP GLIPR2 IL1B LHCGR ADCY9 P2RY1 EMP2 ADCY4 RAPGEF2 BMPER PID1 BMP2 CDH5 ENG KL BDNF FYN SH2D3C CD44 CCL3L1 CCDC88A BAG4 CAV1 BMPR2 ADCYAP1R1 C5AR1 HMGCR FGF10 PRKAR1A CDC42 MIR27B MARCO NEDD9 IL1RN GAS6 SLC11A1 TGFBR2 MOB1B IL23A FGR RHOA ZEB2 AVPI1 CD36 CLCF1 HBEGF CD33 ADAM17 RAP1A PPP1R15B ITGA5 MAP3K8 FZD4 CAV2 CAMTA1 IFNK RGCC ADRB2 TRAF6 LAMTOR3 CRK SPRY2 WNT3A ARHGEF2 MAPK8IP1 TXN PDGFA NODAL SORBS3 LRP4 MAP2K3 ROCK2 ARRB1 CCL22 SDCBP NPNT ACSL3 PTAFR PLAUR ROCK1 DAB2 TNFSF15 THBS1 CDK9 SPAG9 PDE8A CCL3 CDKN1A PTPRC EPGN IRAK2 KCTD20 CCL4 TLR4 MIR24-2 CCND2 XCL2 PLEK INHBA PINK1 PPP2R5A OXSR1 PIK3R5 GNAI2 HES1 CALM2 IL24 PTH1R TGFB2 STK24 NCKAP1L ARL6IP5 CD80 CNTF PPP2CA FLT1 CCNY ADCY2 AREG IL6 DNAJC27 BCAR3 PSEN1 SOCS3 MAGI2 JUN NOTCH1 ZFP91 HRH1 ADRA1A PDE5A BMP3 MAP4K4 MTMR9 PPP1R15A RAPGEF1 CCR7 ACKR3 PRKCE GPR183 OSM MALT1 PRKACA TNFRSF10B RASSF2 GPRC5A RALB NDST1 FGFR4 ACSL1 GPR37L1 SNX9 UBB CALM1 KLB PKD2 CD74 WNT11 TIMP2 TGFB1 VAV3 PEA15 TEC FPR2 MIR23A SH3RF3 DUSP5 MAP3K2 RELL1 TERF2IP CD81 NQO2 CCR1 NPTN CCL20 ICAM1 ANKLE2 HSPA2 FGF2 IL18 NEK1 LAT NBN ARRB2 TIAM1 CXCR4 HSP90AA1 EPHA4 TAB2 RIPK2 HAVCR2 ISCU MAP3K4 CD19 LIMCH1 STK4 RET COPS8 RAPGEF3 KIT EDN1 PAK2 FNIP2 PTEN DUSP7 MMD FGFR1 DAZAP2 NRG1 CCND3 IQGAP1 MAPKAP1 EHD4 SMAD4 BANK1 FLT4 SMPD1 SPHK1 CSF2 ABI1 UBE2V1 EGR1 PPP2R3C GREM1 CDON C5AR2 GHR CDKN1B DUSP6	down	**
GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION	0.0007308	0.0178880	0.4772708	-0.2129454	-1.271052	589	FFAR4 RBP4 RAB11FIP1 SIDT2 IL17RB IL1A FCN1 ADTRP IL1B SLC51B NUP54 INSIG1 FYN LPL HCAR2 INPP5K BAG4 VAMP2 HMGCR CDC42 IL1RL1 GAS6 CD22 FGR NUMB EDEM1 APOD CD36 ANXA1 MIR146A CNST CARD16 CD33 CACNA2D2 FOXA2 RAPGEF4 RAP1A ANXA5 ABCG1 FOXP1 SLC7A11 LCP1 STOM GATA3 PPP3CA RGCC TRAF6 NDEL1 SFRP1 SPTBN1 PPP1R13B CRTAM SRGN TCF7L2 UBE2D3 TXN CD58 PPP3CC IL10 ARRB1 CASP1 ACSL3 REST ARNTL KLF7 GAPVD1 MYRIP CTSD CCL3 DPH3 PER2 CADM1 TLR4 ARC MIR24-2 FRMD4A CPT1A CLEC9A PINK1 RUFY3 TP53BP2 TGFB2 SNX3 KCNA5 PKIG MYO1C IL6 DNAJC27 SAR1A CD160 PSEN1 GLUD1 RAC2 CARD8 PLK3 DNAJA1 IFNGR1 PTGER4 CCR7 PIK3R1 UBAC2 PRKCE OSM GRASP RAB8A UNC13B RBM22 PRKACA TCP1 YWHAZ PPM1F CD34 MBP MAPK8 PKIA CHIA TGFB1 PARD6A SERPINB1 LRRC32 APBB1 PIK3C3 IRS2 PPP3R1 CD81 EXOC1 ORM2 CSNK2A2 PPID SYT11 BNIP3L PCM1 EPB41L5 TIAM1 RIPK2 NLRP3 HSPA8 SP100 HAVCR2 IPO5 SREBF2 GLUL TLR10 RAPGEF3 ADORA2A AIM2 PSMD9 ENY2 BANK1 PMAIP1 PIM3 DISP1 HTRA2 ACVR1C CHP1 C5AR2 EXPH5 TMEM30A KCNE1 FKBP1B CLEC4E C5 MAPK1 CLOCK MYH10 TREM2 SH3GLB1	down	*
GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND	0.0000823	0.0033073	0.5384341	-0.2045383	-1.268216	936	SLC6A4 GPD1 CXCL3 KMO RAMP3 SIDT2 LPIN2 IL1A SASH1 EDNRB SCIMP PPARG CD55 CPEB2 IL1B LHCGR ADCY9 P2RY1 ADCY4 RAPGEF2 PTPRE PID1 INSIG1 KL PCSK9 FOLR1 FYN LPL LY86 RGS9 INPP5K CAV1 BAIAP2 CALCRL AQP9 MYD88 VAMP2 PLEKHA1 TBXA2R HMGCR PRKAR1A NR3C1 IL1RN GAS6 TRIB1 CASP9 RHOA PDE2A BRINP3 CD36 ANXA1 MIR146A SSTR1 ATP2B1 TRA2B RRAGC CARD16 FOXA2 RAP1A CLEC7A TNIP3 ANXA5 FZD4 LITAF KLF10 CAV2 ADIPOR1 EIF4E PPP3CA NR4A1 SIRPA ADRB2 TRAF6 NFE2L2 NDEL1 LAMTOR3 CRK SFRP1 WNT3A KANK2 ZEB1 ARHGEF2 SPI1 PDE4D TXN ATP6V1H ATP6V1B2 FOXC2 RHOB IL10 ROCK2 STAT5A ARRB1 RAB12 FOXO1 SRSF5 SORBS1 CASP1 PTAFR KLF4 ID3 KLF9 ROCK1 KLF11 SOCS2 ATP6V1D KLF7 LY96 PDE8A CCL3 SSH1 NFKB1 PDE3B P2RY2 SIK2 KCNMB1 CXCL2 IRAK2 VIM AXL ATP6V0D2 TLR4 PIK3C2A INHBA CPT1A PINK1 GNAQ CYP26B1 GNAI2 TBC1D4 IL24 BACE1 ACTR2 HCK SRF SLC25A33 PDK4 KANK1 MYO1C WNT9A SLC8A1 CD80 ADCY2 IL6 PSEN1 SOCS3 ESD APPL1 RAB8B RWDD1 JUN CPEB4 GABPA RAB31 USO1 ETS1 HRH1 ATP6V0B CARD8 PALM RAPGEF1 PTGER4 PIK3R1 IRF8 PRKCE GRB2 CREB1 PTGER2 MALT1 RAB8A UNC13B PRKACA CXCL5 GPR37L1 FOS ATP6V0D1 ADNP2 RHOQ KLF2 FOXO3 PKD2 MAPK8 TREX1 WNT11 DDX18 HNRNPD EPHA3 TGFB1 CD6 FPR2 GNAI1 ATP6V1A CD86 IRS2 PIM1 ATP6V0C PLSCR4 SLC8A3 GLRA1 SOD2 KLRC4-KLRK1 ACTN2 PLAA KAT2B PDE4B TSPO SOD3 ICAM1 SESN1 IL18 IL18RAP ABL2 TFPI HTR6 ARRB2 OSR1 TIAM1 EPHA4 RIPK2 NLRP3 PTCH1 ACTB HAVCR2 IPO5 OSER1 MBD5 DAPK1 FDX1 SIN3A NFKBIA GLRX2 RET RAPGEF3 EDN1 KLRK1 PTEN	down	**
GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY	0.0001062	0.0040443	0.5384341	-0.2064363	-1.266345	856	SMAD6 TRIM71 ANGPT4 SEMA6A EREG TMEM100 ACVRL1 SOSTDC1 TEK HHEX SFRP4 IL1B TIE1 WNT4 GREM2 RAPGEF2 PTPRE BMPER PID1 BMP2 CDH5 ENG KL BDNF FOLR1 FYN INPP5K CAV1 BAIAP2 CITED2 CDH13 BMPR2 PLEKHA1 RBM14 FGF10 ELMO1 CDC42 TGFBR3 NCF2 GAS6 CBL TGFBR2 CD8A FGR RHOA TXNIP SH2D6 APOD TMPRSS6 MIR146A MMRN2 SH2B3 LTBP4 HBEGF ADAM17 LIFR RASGRP4 TMEM204 ITGA5 HSPB1 NLK FZD4 CAV2 ADIPOR1 GATA3 ADRB2 NDEL1 CRK SFRP1 SPTBN1 SPRY2 ZFYVE16 ZEB1 UBE2D3 ATP6V1H PDGFA RAB14 ATP6V1B2 FOXC2 NODAL TIPARP PTPN12 ROCK2 CSRNP1 PRDM16 STAT5A PTGIR DUSP3 FOXO1 SDCBP SORBS1 NPNT PLAUR ZNF423 ROCK1 DAB2 ZFAND5 MVB12B THBS1 SOCS2 ATP6V1D CLDN5 SOCS5 SIK2 EPGN VIM AXL ATP6V0D2 IGFBP2 CEP57 ACTR3 EPS15 PIK3C2A SMAD7 INHBA CUL5 MATK SH2D2A UBASH3B VEPH1 NUS1 GNAI2 HES1 HTRA4 MIR17HG CRIM1 ACTR2 TGFB2 HCK NRROS NCKAP1L PDK4 CD8B KANK1 RBPJ MYO1C FLT1 AREG WASF2 PSEN1 SOCS3 ADAMTSL2 APPL1 MAGI2 JUN NOTCH1 LTBP2 BMP3 ATP6V0B SHOC2 RAPGEF1 FERMT2 SKIL PIK3R1 DDX5 GRB2 CREB1 NPR1 CD7 FSTL3 RASSF2 APH1B GPRC5A NDST1 FGFR4 FOS SPRY4 ATP6V0D1 RHOQ UBB KLB FOXO3 EPHA3 SORT1 TGFB1 PARD6A VAV3 ZFYVE9 TGFB1I1 ATP6V1A LRRC32 IRS2 ATP6V0C DOK2 MYOCD TOB1 NPTN LTBP1 SMAD2 LDLRAD4 FGF2 ARPC2 FKBP1A EPN2 ARRB2 RTN4 TIAM1 CDKN1C HSP90AA1 DACT2 EPHA4 UBE2D1 ACTB EPHA2 CREBBP MBD5 SRMS STAM2 ING2 RET GTF2F2 KIT ARPC5 PAK2 ETV2 PTEN SKI LTBP3 FGFR1 NRP2 NRG1 CCND3 GRB10 IQGAP1 SMAD4 FLT4 SKOR1 HNRNPH1 ARHGEF18 ABI1 SETX CYBA ATP6V0A1 KALRN ACVR1C EGR1 GREM1	down	**
GO_IMMUNE_SYSTEM_DEVELOPMENT	0.0001564	0.0054275	0.5188481	-0.2064176	-1.262054	808	EPAS1 RTKN2 CLEC1B SWAP70 CD101 TEK ACE TAL1 KLF13 PPARG HHEX GATA2 SPN SNX10 DCSTAMP WNT4 OSCAR LYL1 PDE1B LMO2 TMOD3 SAMHD1 CITED2 EML1 FGF10 CDC42 TGFBR3 GAS6 TET2 PSMD5 TGFBR2 TRIB1 LILRB3 IL23A CD8A CASP9 RHOA ANXA1 SH2B3 CLCF1 FBXO7 ADA SBDS ADAM17 WNT2B RASGRP4 PICALM KLF10 FOXP1 KLF6 HLX MS4A1 IFNK ASH2L GATA3 JAM3 RB1 IL18R1 TRAF6 NFE2L2 SFRP1 WNT3A ZEB1 SPI1 TFRC ARL11 TIPARP FLI1 ZMIZ1 EVI2B IL10 AGO4 MMP21 NRARP AGO3 SLC46A2 KLF4 REST FUT7 THBS1 CEBPA SOCS5 MPL CCL3 PTPRC AXL KIRREL3 ID2 TLR4 FCER1G SMAD7 PLEK ZMPSTE24 LYAR INHBA IL7R UBASH3B CYP26B1 PAFAH1B1 HES1 MIR17HG ADD1 TGFB2 SRF NRROS NCKAP1L RBPJ IL17D CD80 IL6 WASF2 PKNOX1 PSEN1 JUN PSMA1 MITF NOTCH1 GABPA CUL4A ETS1 TYROBP HSPA1B JUNB OSTM1 DNASE2 PTGER4 CCR7 ATXN1L SP3 PIK3R1 PABPC4 CD83 IRF8 GPR183 CREB1 OSM MALT1 SIGLEC15 RC3H1 ZBTB24 AP3B1 FSTL3 TBX21 RASSF2 ZNF683 SNRK WDR7 CD34 PLCG2 FOS RRAS KLF2 CD164 AZI2 TNFSF13 PSMD12 RUNX3 FOXO3 TREX1 KAT8 CD74 CR1 CCR4 TGFB1 EPB42 CD1D ZBTB1 JMJD6 YTHDF2 CBFA2T3 CD86 PDCD1 PIM1 SLC8A3 CD81 LGALS3 MEIS1 CCR1 MFNG N4BP2L2 GPR18 KAT2B CCR6 IL18 WDR1 NBN SEMA4A CEBPD PIP4K2A CDKN1C MFAP5 DACT2 RIPK2 NLRP3 TOB2 CCR9 HAVCR2 PSME4 EPHA2 CREBBP CD19 STK4 SIN3A NFKBIA RET KIT DOCK10 CD3G ETV2 DNAJB9 TNFSF9 GPR171 RORA ITCH PSMD6	down	**
GO_CELLULAR_COMPONENT_MORPHOGENESIS	0.0001775	0.0060370	0.5188481	-0.2022722	-1.249828	925	TNR LIMS2 WEE1 DAB1 SEMA6B SEMA3G CLEC1B SEMA6A SIDT2 WTIP COL25A1 TEK PHACTR1 DLC1 TAL1 PECAM1 FGD5 ROBO4 P2RY1 RDX DPYSL2 RAPGEF2 PLA2G10 LIPA PID1 TRPV2 CDH5 FIG4 BDNF FYN SHANK3 EGR2 CD44 TMOD3 SOX17 RADIL CORO1C MYADM NEDD4L BAIAP2 CDH13 BMPR2 CDC42EP2 PRKAR1A MEF2A CDC42 NEDD9 CD9 DSCAML1 EPB41L3 SCARA3 FGR HEG1 CASP9 RHOA ZEB2 NUMB SEMA6D ANXA1 MYOZ1 PTPRM SEMA3B TTL HECW2 PLXNA2 CSRP1 RANBP9 PARVG PICALM FZD4 GATA3 PPP3CA ZMYM6 PLXNA4 RB1 ISLR2 NDEL1 CRK SPTBN1 WNT3A ARHGEF2 ITSN2 TCAP ZNF365 GPM6A NODAL ATP10A RHOB LRP4 ADARB1 AGO4 PTPRO LIMS1 ZSWIM6 TRIM46 NES PSPN ROCK1 PARVB VASP KLF7 MPL CLIC4 SEC24B FMNL3 LAMC3 CCL3 SSH1 C9orf72 ARHGEF26 AXL KIRREL3 ID2 ARC SS18L2 WASF3 ZMPSTE24 MATN2 PEAK1 UNC5A IL7R MYH11 PAFAH1B1 RUFY3 HES1 ADD1 ACTR2 SIAH1 TGFB2 LMOD3 HEXB HCK SRF NCKAP1L KANK1 FMNL2 VAMP3 FRY TMOD1 WASF2 SGK1 PSEN1 CABP4 PIKFYVE LAMB2 NOTCH1 RHOBTB2 LIMD1 RAC2 MAP4K4 CNTN4 RHOG APBB2 RHOJ PALM FERMT2 SNX2 SKIL IFRD1 PIK3R1 GRB2 FRYL CREB1 RAB8A RTN4R SNX1 CAP1 TRAK2 PREX2 PALMD PANK2 AGFG1 RHOQ UBB KLF2 EPHA3 EPB42 ZRANB1 HECW1 MTMR2 YTHDF2 TGFB1I1 APBB1 IRS2 CNTNAP1 SLIRP C8orf37 DOK2 NPTN CLASP2 GNA13 ACTN2 MACF1 PLAA ADAM10 IST1 PITPNA UNC13D ICAM1 PDLIM5 ARPC2 WDR1 EPB41L5 LMOD1 SEMA4A RTN4 CDC42EP3 TIAM1 CXCR4 HSP90AA1 DACT2 TMOD2 EPHA4 ARHGAP18 PTCH1 ACTB MEGF9 BRWD1 EPHA2 SSH2 RND1 ULK2 PARVA NEK3 STK4 CUL3 SIN3A RET ADORA2A KIT EDN1 DOCK10 PTEN B3GNT2	down	**
GO_ACTIN_FILAMENT_BASED_PROCESS	0.0018759	0.0339477	0.4550599	-0.2057253	-1.243937	632	SWAP70 TEK PDLIM2 PHACTR1 DLC1 FGD5 ATXN3 WNT4 EMP2 RDX GPR65 ARHGEF15 SHANK3 TMOD3 CGNL1 CCDC88A INPP5K BAG4 KANK3 CAV1 CORO1C MYADM NEDD4L BAIAP2 CDC42EP2 ESAM S1PR1 FGF10 PRKAR1A MEF2A ELMO1 CDC42 NEDD9 EPB41L3 CIT SCN5A RHOA ANXA1 MYOZ1 CORO6 CSRP1 PARVG SPIRE1 LCP1 DES JAM3 RGCC CRK SFRP1 SPTBN1 ARHGEF2 TCAP PDE4D SETD3 PDGFA CNN1 SORBS3 EPB41L2 RHOB ROCK2 AMOTL1 ARRB1 SYNPO TNNC1 SDCBP SORBS1 BST1 DAAM2 ROCK1 PARVB VASP MYO1B FMNL3 SSH1 COTL1 VIM C9orf72 ACTR3 CAPZA2 WASF3 PLEK DSTN RAP1GDS1 MYH11 PAFAH1B1 RUFY3 ADD1 ARHGDIB ACTR2 LMOD3 HCK MTPN SRF NCKAP1L ARHGAP17 KCNA5 KANK1 MYO1C FAM107A FMNL2 SCN4B TMOD1 WASF2 SYNPO2 PDCD6IP RHOBTB2 RAC2 TYROBP ARHGEF10 RHOG RHOJ PTGER4 CCR7 IQSEC3 PIK3R1 GMFG PRKCE GRB2 SIGLEC15 CAP1 THSD7B PPM1F GAS2L3 ESPNL SNX9 RHOQ EHD2 WNT11 WHAMMP3 EPHA3 TESK2 PDLIM1 KCNN2 CLASP2 ACTN2 PDE4B PRICKLE4 ICAM1 PDLIM5 ABL2 ARPC2 WDR1 EPB41L5 LMOD1 XIRP1 IQSEC1 CDC42EP3 TMOD2 ARHGAP18 DIXDC1 ACTB GPD1L SSH2 RND1 SDAD1 PARVA LIMCH1 CUL3 RAPGEF3 KIT EDN1 ARPC5 EPB41L4A	down	*
GO_REGULATION_OF_GROWTH	0.0032952	0.0498411	0.4317077	-0.2088088	-1.242913	529	SLC6A4 TNR RBP4 SEMA6B SEMA3G SEMA6A ACVRL1 IL17RB CXCL16 SGK3 PPARG WFDC1 FBP1 DCSTAMP DPYSL2 TRPV2 BDNF SOX17 KIAA1109 NEDD4L BMPR2 CDC42 TGFBR3 NEDD9 GAS6 USP47 EPB41L3 TGFBR2 RFTN1 RHOA SEMA6D TBX2 WWC2 MYOZ1 LTBP4 SEMA3B HBEGF CACNA2D2 TTL ADAM17 LATS2 HLX ADIPOR1 ADRB1 FAM122A PLXNA4 RB1 ADRB2 ISLR2 NDEL1 SFRP1 WNT3A BNIPL ITSN2 FOXC2 EXOSC9 STAT5A PPT1 SDCBP TRIM46 YBX3 SOCS2 SOCS5 KIF26A CDKN1A ST7L IGFBP2 TAF9 ZMPSTE24 INHBA ADIPOR2 TBX5 WFS1 PAFAH1B1 RUFY3 MIR17HG CDKN2AIP TGFB2 MTPN SRF BTG1 SLC25A33 SERTAD2 RBPJ FAM107A PPP2CA PRDM11 SGK1 EBAG9 SOCS3 NOTCH1 HSPA1B EPC1 APBB2 IFRD1 CREB1 OSM NPR1 RTN4R RPS6KA1 EGLN2 PPM1F MORF4L1 ADNP2 EPPK1 WNT11 ING3 CHPT1 SAV1 TGFB1 OSGIN1 APBB1 PIM1 MEIS1 MYOCD GATA6 MACF1 RGS2 PLAA ADAM10 IST1 FGF2 INO80 SEMA4A RTN4 CXCR4 LRP12 PTCH1 ACACB MT1M ULK2 MBD5 ING2 STK4 SIN3A EDN1 PAK2 PTEN FGFR1 MIR548C ITCH ZFPM2 MT2A CREG1 SMAD4 SPHK1 EIF4G2 CYBA KAT5 HTRA2 GREM1 GHR CDKN1B DUSP6 MAPK1 ING1 DCUN1D3 OSGIN2 S100A8 CPNE9 NOG	down	*
GO_INNATE_IMMUNE_RESPONSE	0.0012958	0.0263691	0.4550599	-0.2043212	-1.242577	692	POLR3H SIRPB1 NLRC4 SLPI EREG CD300LF FCN1 CXCL16 SCIMP SIGLEC16 PPARG CD55 FCN3 MNDA FYN CD44 LY86 CCL3L1 SAMHD1 CLEC12B CAV1 MYD88 CDC42EP2 CD300E CLEC10A RBM14 CDC42 MARCO NCF2 OTUD4 PSMD5 LAMP1 SLC11A1 RFTN1 IL23A FGR CD36 ANXA1 MIR146A CLEC7A MASP1 TNIP3 IFI30 RNF125 PTX3 IFNK SERPINB9 GATA3 SIRPA TRAF6 GRN CRK CRTAM ARHGEF2 UBE2D3 CD58 ADARB1 CFD CCL22 RAB12 BIRC2 MEFV MPEG1 CASP1 SLC46A2 PTAFR LY96 UBQLN1 CCL3 NFKB1 CADM1 IRAK2 VIM AQP4 AXL CCL4 TLR4 ACTR3 SFTPD XCL2 CAPZA2 FCER1G KLRD1 HLA-DQA1 C4BPB CD300LB ACTR2 PIAS1 HCK MYO1C VAMP3 MUC3A CD160 CTSS SOCS3 APPL1 OASL PPP6C SEC14L1 C1QA PSMA1 TYROBP TREM1 HSPA1B IFNGR1 JAK1 IPO7 IRF8 PRKCE MALT1 SIGLEC15 PRKACA ZNF683 PLCG2 UBB PELI1 YTHDF3 PSMD12 ICAM2 TREX1 KLRC2 CR1 PIK3AP1 SMPDL3B IRF5 STXBP3 SIGLEC14 AKIRIN2 AP1G1 CD1D ZBTB1 CD6 FPR2 YTHDF2 PDE12 NLRP6 IFNAR1 PIK3C3 CNOT7 LGALS3 KLRC4-KLRK1 IGHV3-23 KYNU SERINC3 MR1 IFNLR1 CCL20 UNC13D ICAM1 IL18 IL18RAP ARRB2 RTN4 CALCOCO2 TAB2 RIPK2 NLRP3 UBE2D1 SP100 HAVCR2 PSME4 G3BP2 CREBBP ICAM3 DAPK1 TLR10 SIN3A NFKBIA EDN1 PAK2 KLRK1 LYST MCOLN2 AIM2 ITCH PSMD6 MT2A PSMD9 SFPQ PUM1 IRF2 UBE2V1 CYBA EPG5 EGR1 C1QB TREML1 CX3CR1 CLEC4E C5 TREM2 NCF1 ZYX S100A8 PIK3CG SIGLEC10 MUL1 IFIT5 HLA-DRB1 WNT5A SSC5D MAP4K2 UBE2N BCL10 TRIM13 CAPZA1 MATR3 ANKHD1 HMGB1 DDX21 NMI EP300 IRF1	down	*
GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM	0.0011574	0.0242831	0.4550599	-0.1999231	-1.225704	815	POLR3H SIRPB1 SIGLEC11 NLRC4 SLPI EREG ACP5 CD300LF FCN1 CXCL16 SCIMP SIGLEC16 PPARG CD55 FCN3 SPN PGC IL1B MNDA FYN CD44 LY86 CCL3L1 SAMHD1 CLEC12B CAV1 MYD88 CDC42EP2 CD300E C5AR1 CLEC10A RBM14 CDC42 MARCO NCF2 OTUD4 PSMD5 LAMP1 SLC11A1 RFTN1 IL23A FGR CD36 ANXA1 MIR146A DNAJC3 ADAM17 CLEC7A MASP1 TNIP3 IFI30 RNF125 FOXP1 PTX3 IFNK SERPINB9 GATA3 SIRPA TRAF6 GRN CRK CRTAM ARHGEF2 UBE2D3 RAB14 CD58 ADARB1 IL10 CFD CCL22 RAB12 BIRC2 MEFV MPEG1 CASP1 SLC46A2 PTAFR LY96 UBQLN1 ATG7 CCL3 NFKB1 COTL1 CADM1 PTPRC IRAK2 VIM AQP4 SELP AXL CCL4 TLR4 ACTR3 SFTPD XCL2 CAPZA2 PRF1 FCER1G ZMPSTE24 KLRD1 HLA-DQA1 C4BPB ANXA3 CD300LB ACTR2 PIAS1 HCK RBPJ MYO1C VAMP3 IL6 MUC3A CD160 CTSS SOCS3 APPL1 OASL PPP6C SEC14L1 C1QA PSMA1 DDX17 TYROBP TREM1 HSPA1B IFNGR1 JAK1 IPO7 IRF8 PRKCE MALT1 SIGLEC15 UNC13B PRKACA ZNF683 IGKV3-20 PLCG2 UBB PELI1 YTHDF3 PSMD12 ICAM2 TREX1 KLRC2 ZNF175 CR1 PIK3AP1 SMPDL3B IRF5 STXBP3 SIGLEC14 AKIRIN2 AP1G1 CD1D ZBTB1 CD6 FPR2 YTHDF2 PDE12 NLRP6 IFNAR1 PIK3C3 CNOT7 LGALS3 KLRC4-KLRK1 EXOC1 IGHV3-23 KYNU SERINC3 MR1 IFNLR1 CCL20 SYT11 UNC13D ICAM1 BNIP3L IL18 IL18RAP VGF ARRB2 RTN4 CALCOCO2 TAB2 RIPK2 NLRP3 UBE2D1 SP100 HAVCR2 PSME4 EPHA2 G3BP2 CREBBP ICAM3 DAPK1 TLR10 SIN3A NFKBIA EDN1 PAK2 KLRK1 LYST MCOLN2 AIM2 ITCH PSMD6 MT2A PSMD9 SFPQ PUM1	down	*
GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION	0.0007941	0.0188470	0.4772708	-0.2011246	-1.216783	797	LIMS2 DAB1 SEMA6A TMEM100 ACVRL1 CD101 TAL1 PPARG GLIPR2 GATA2 SFRP4 IL1B DCSTAMP WNT4 RAPGEF2 PLA2G10 RAMP2 BMP2 TRPV2 CDH5 ENG FIG4 BDNF FYN LPL SHANK3 SOX17 MYADM NEDD4L BAIAP2 BMPR2 MEF2A CDC42 NEDD9 GAS6 TGFBR2 SCARF1 TRIB1 IL23A RHOA ZEB2 NUMB BRINP3 CD36 ANXA1 MIR146A CLCF1 ADA ARSB RAP1A PLXNA2 CLEC7A FZD4 KLF10 HLX GATA3 RBM4 PLXNA4 RB1 RGCC ISLR2 TRAF6 NFE2L2 NDEL1 GRN CRK SFRP1 WNT3A ZEB1 ARHGEF2 HNRNPU ITSN2 TCF7L2 ZNF365 CYB5D2 SETD3 ZMIZ1 EVI2B MSR1 PRDM16 SNAI1 SDCBP NPNT BNIP2 LIMS1 REST DAB2 ARNTL ADAMTS9 CEBPA SOCS2 CLDN5 SOCS5 MPL SPAG9 CCL3 NFKB1 PTPRC AXL ID2 SS18L2 CD53 INHBA TBX5 IL7R CYP26B1 PAFAH1B1 RUFY3 HES1 ADD1 AKIRIN1 MEDAG ACTR2 NCOA1 TGFB2 LMOD3 PIAS1 SRF SRGAP2C BTG1 NCKAP1L SNX3 RBPJ WNT9A CD80 CNTF IL6 PSEN1 SOCS3 MAGI2 NDNF JUN CCDC3 NOTCH1 RASSF10 ETS1 PDE5A TYROBP HSPA1B JUNB RAPGEF1 SKIL CD83 ZNF804A CREB1 MALT1 RPS6KA1 AP3B1 CD34 BLOC1S6 FOS RRN3 RUNX3 EHD2 FOXO3 CD74 MME EPHA3 TIMP2 SAV1 TGFB1 EHD1 TCF4 ZBTB1 TGFB1I1 APBB1 CD86 SOD2 MYOCD CCR1 NPTN GATA6 MACF1 RGS2 PLAA TSPO IST1 SMAD2 JUND UNC13D FGF2 IL18 ABL2 ARPC2 ARRB2 CEBPD TIAM1 CXCR4 EPHA4 RIPK2 NLRP3 PTCH1 STK4 SIN3A RET KIT EDN1 ETV2 PTEN LTBP3 TNFSF9 MMD C21orf91 FGFR1	down	*
GO_CHEMICAL_HOMEOSTASIS	0.0015591	0.0301797	0.4550599	-0.1934413	-1.206473	904	SLC24A4 RBP4 EPAS1 HCRTR1 GPR17 SLC31A2 RAMP3 SIDT2 CD52 HMOX1 SWAP70 ABHD5 SLC12A6 MCOLN1 EDNRB PPARG GPIHBP1 CD55 GATA2 SFRP4 FABP4 F2RL3 SNX10 ADCY9 P2RY1 GPR65 ADCY4 PLA2G10 CDH5 INSIG1 KL PCSK9 TRPC3 FYN LPL JPH4 CCRL2 INPP5K CAV1 NEDD4L AQP9 CRY2 ADRA1D GTF2I SLC39A8 ADCYAP1R1 TBXA2R C5AR1 S1PR1 HMGCR PRKAR1A MIR27B GAS6 ACSM1 CYP4A11 SLC11A1 TLCD2 SCN5A ACOXL CD36 JPH2 TMPRSS6 MIR146A ATP2B1 TRA2B FOXA2 KCNK3 RAP1A ABCG2 PICALM ANXA5 ABCG1 GLS MALL SLC7A11 MS4A1 ADIPOR1 CLN5 PPP3CA SLC25A37 GRN PDE4D TCF7L2 TFRC ATP6V1H TMEM38B ATP6V1B2 FBXL5 GPR4 CYBRD1 FABP5 ARRB1 SYNPO PTGIR PPT1 FOXO1 KCNMA1 SLC12A4 SLC7A8 CEBPA ATP6V1D MAFG KLF7 RMDN3 CLIC4 CCL3 P2RY2 NR1D2 PTPRC AQP4 ATP6V0D2 PTGER3 SFTPD SMAD7 ADIPOR2 RAP1GDS1 WFS1 HTT GPR157 UBASH3B CYP26B1 NUS1 GNAI2 CALM2 PLCD1 PTH1R HEXB SRF PRCP KCNA5 PDK4 MYLIP S1PR4 SLC8A1 ADCY2 PDE6A PSEN1 PDE6B AQP3 SLC9B1 CNNM2 HK3 ADRA1A JPH1 ATP6V0B GSTO1 PTGER4 CCR7 PIK3R1 ACKR3 PRKCE PTGER2 NPR1 GRIA1 UNC13B ATP13A3 PRKACA SLC10A7 HOMER1 SUCNR1 CLN3 FGFR4 PLCG2 ATP6V0D1 PNPLA2 CALM1 FOXO3 PKD2 SLC4A5 SYPL2 PNPLA3 CCR4 SPOP STXBP3 EPB42 EHD1 FPR2 ATP6V1A MCUR1 IRS2 SLC24A1 ATP6V0C SLC8A3 SOD2 CCR1 SCARA5 NPTN CRY1 GNA13 GPR18 CALB1 TSPO COMMD9 CCR6 ICAM1 FGF2 IL18 SLC34A2 ABL2 FKBP1A SLC31A1 VGF SCN7A ELOVL1 RTN4 SLC24A5 TPT1 TIAM1 CXCR4 CYB5R4 ORMDL1 CCR9 PTCH1 MT1M GPD1L SOAT1 ISCU BOK MBD5 CD19 SREBF2	down	*
GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS	0.0010482	0.0229437	0.4550599	-0.1910247	-1.176444	980	FFAR4 ANGPT4 DAB1 HCRTR1 EREG RAMP3 ACVRL1 IL1A SASH1 TEK ACE DLC1 EDNRB SCIMP TAL1 PECAM1 ADTRP GLIPR2 IL1B SLC51B ADCY9 P2RY1 EMP2 ADCY4 RAPGEF2 BMPER BMP2 CDH5 ENG KL ARRDC4 BDNF FYN SH2D3C CD44 CCL3L1 CCDC88A BAG4 CAV1 TBC1D7 BMPR2 C5AR1 HMGCR FGF10 DYRK1A PRKAR1A CDC42 MIR27B MARCO NEDD9 IL1RN GAS6 SLC11A1 TGFBR2 RCHY1 IL23A RHOA ZEB2 AVPI1 CD36 CLCF1 HBEGF CD33 ADAM17 LMNA RAP1A PPP1R15B ITGA5 MAP3K8 FZD4 CAV2 CAMTA1 IFNK GATA3 RGCC ADRB2 TRAF6 LAMTOR3 CRK SPRY2 WNT3A ARHGEF2 MAPK8IP1 TXN PDGFA NODAL SORBS3 LRP4 MAP2K3 ROCK2 ARRB1 CCL22 BIRC2 SDCBP NPNT PLAUR ROCK1 DAB2 TNFSF15 THBS1 ARNTL CDK9 SPAG9 UBQLN1 ATG7 PDE8A CCL3 CDKN1A PTPRC EPGN IRAK2 TADA2B CCL4 TLR4 MIR24-2 CCND2 XCL2 WDR48 SMAD7 INHBA PINK1 WFS1 PPP2R5A OXSR1 PEF1 PIK3R5 PRDM5 GNAI2 HES1 CALM2 IL24 TGFB2 PIAS1 STK24 TOPORS NCKAP1L ARL6IP5 FAM107A CD80 CNTF PPP2CA FLT1 CCNY ADCY2 AREG IL6 DNAJC27 BCAR3 PSEN1 SOCS3 MAGI2 JUN NOTCH1 ZFP91 ADRA1A PDE5A BMP3 MAP4K4 PPP1R15A RAPGEF1 CCR7 ACKR3 PRKCE GPR183 OSM MALT1 PRKACA TNFRSF10B RASSF2 GPRC5A RALB NDST1 FGFR4 ACSL1 GPR37L1 SNX9 UBB PELI1 CALM1 KLB PKD2 CD74 WNT11 TIMP2 TGFB1 PEA15 TEC FPR2 MIR23A SH3RF3 DUSP5 MAP3K2 RELL1 TERF2IP PHF19 CD81 NQO2 CCR1 WBP2 NPTN CRY1 CCL20 ICAM1 ANKLE2 HSPA2 FGF2 IL18 NEK1 LAT FKBP1A NBN ARRB2 TIAM1 CXCR4 HSP90AA1 EPHA4 TAB2 RIPK2 UBE2D1 HAVCR2 MAP3K4 ING2 LIMCH1 STK4 CUL3 RET COPS8 RAPGEF3 KIT EDN1 PAK2 FNIP2 PTEN DUSP7 MMD FGFR1 DAZAP2 NRG1 CCND3 IQGAP1 MAPKAP1 EHD4 SMAD4 BANK1 BMI1 FLT4 SMPD1 SPHK1 DCUN1D2 CSF2 ABI1 UBE2V1 KAT5 JDP2 EGR1 PPP2R3C GREM1 CHP1 CDON C5AR2 GHR CDKN1B DUSP6 AKTIP CX3CR1 C5 MAPK1 DCUN1D3 TREM2 NCF1 RB1CC1 CCNK FPR1 KMT2E NDFIP1 SNW1 CCNT2 PIK3CG MUL1 WNT5A UBE3A MAP4K2 UBE2N KIDINS220 BCL10 CTR9 PRDM6 AKAP12 GPR55 HMGB1 IL5 NMI PDE6G CD3E PAXBP1 TNFSF18 ATP2B4 MAP3K1 RNF111 CNTN1 GDF7 CSF3 CCNYL1 RAB1A WDFY2 CTF1 SIRT1 FNIP1 DUSP22 PLA2G5 CSPG4 CFLAR PTGS2	down	*

C6 oncogenic Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
RPS14_DN.V1_UP	0.0000000	0.0000000	0.8266573	-0.4373064	-2.323931	159	SLC31A2 KMO IL1B MNDA LPXN PTPRE PID1 LY86 ST3GAL6 RASAL2 FLVCR2 BCL2A1 NCF2 CD9 FUCA1 IGSF6 PILRA PLA2G7 ADA CLEC7A ANPEP SIRPA CRTAM TFEC PDE4D PDGFA RHOB EVI2B PTPRO CASP1 BST1 STX3 MPL LY96 CDKN1A ITGAX TM6SF1 EVI2A SH2D2A ANXA3 CRIM1 VWF HCK FRY HESX1 CTSS SH3BP5 RAB31 KCTD12 TYROBP CSTA PTGER4 GPR183 TNFRSF9 NKG7 RIN2 CR1	down	***
STK33_UP	0.0000000	0.0000000	0.9653278	-0.4114223	-2.320325	256	CXCL3 NLRC4 KMO IL1A HMOX1 SLC12A6 CD101 OLR1 CPEB2 IL1B FABP4 GPR65 MIR22HG THBD PID1 EGR2 OTUD1 AQP9 C5AR1 BCL2A1 NCF2 CD9 TRIB1 ZEB2 CD36 ANXA1 NCEH1 HBEGF HECW2 BTG2 KLF6 SLC7A11 CRK TFEC BTG3 RHOB CYBRD1 CSRNP1 RAB12 PTPRO MPEG1 COQ10B TNFSF15 LY96 RIT1 CDKN1A NKIRAS1 CXCL2 CCL4 DUSP1 MAFF CREBRF RNF149 SGK1 RNF141 NECAP1 JUN ARL5B CPEB4 C20orf194 TYROBP TREM1 JUNB OSTM1 MTMR9 DUSP8 PPP1R15A GLIPR1 KBTBD8 FAM177A1 GPRIN3 FOS PELI1 RIN2 BTBD7 MILR1 TGIF1 CDC37L1 DUSP5 MEIS3P1 ATXN1 HBP1 PPP3R1 WBP2 KYNU HINT3 ANKRD12 STX12 NBEAL1 RGS2 CLEC2B ICAM1 TRAC TFPI RTN1 TTLL7 HAVCR2 DAPK1 STAM2 TLR10	down	***
STK33_NOMO_UP	0.0000000	0.0000000	0.9969862	-0.4140711	-2.318521	261	EPAS1 CXCL3 ACP5 KMO IL1A HMOX1 SLC12A6 OLR1 IL1B FABP4 DCSTAMP MIR22HG THBD PID1 EGR2 OTUD1 AQP9 C5AR1 ZEB2 NCEH1 HECW2 CLEC7A BTG2 MAP3K8 KLF6 PTX3 CRK TFEC BTG3 RHOB IL10 CSRNP1 RAB12 PTPRO COQ10B DAB2 TNFSF15 STK17B LY96 RIT1 CADM1 NR1D2 NKIRAS1 CXCL2 CCL4 TM6SF1 DUSP1 CD300C IL7R MAFF LACC1 CREBRF HCAR3 CD80 RNF149 SGK1 RAB8B NECAP1 JUN ARL5B CPEB4 C20orf194 TREM1 JUNB OSTM1 MTMR9 PPP1R15A GLIPR1 KBTBD8 GPRIN3 FOS PELI1 RIN2 BTBD7 KIAA0232 TGIF1 CDC37L1 DUSP5 MEIS3P1 HBP1 PPP3R1 WBP2 KYNU HINT3 ANKRD12 STX12 RGS2 CLEC2B CCL20 ICAM1 CTTNBP2NL CGRRF1 HAVCR2 ULK2 DAPK1 STAM2 TBCEL SIGLEC9	down	***
RPS14_DN.V1_DN	0.0000000	0.0000000	0.8012156	0.4928272	2.203948	152	TRIP13 KIF20A MCM10 PBK DEPDC1 SLC25A21 TBRG4 TUBB2B AGFG2 E2F8 PLK1 ECT2 ESPL1 CDC6 CCNB2 MYBL2 PRC1 ORC1 EXO1 ZNF74 NLE1 KIF23 MKI67 KIF15 TRIM29 SPTB NUP155 SLC29A2 LARS2 KIF2C CAD ERCC2 PES1 GEMIN4 INCENP ISOC2 KIF5A MRPS2 PSAT1 STEAP3 MYO19 TUBG1 DLGAP5 TUBB2A TSPO2 TK1 COLEC11 IL15RA GINS2 SRD5A3 LRRC20 ASNS ELMO3 POLD1 CDC20 DGCR11 SIRT4 GPATCH4 CDR2 MCM5 NEFH SH3TC2 ATAD2 EPCAM KLHL7 PYCR1 SUV39H2 MSH2 IL7 TUBGCP4 ZWILCH ARHGAP11A LLPH RPUSD2 CENPE RRS1 NCAPH MRTO4 SRM BAG2 MRPL12 FBXO5 TLN2 LGR4	up	***
HINATA_NFKB_IMMU_INF	0.0001184	0.0020343	0.5384341	-0.7453313	-2.179084	13	CXCL3 OLR1 IL1B PTX3 NFKB1 CXCL2 IL6 CD83 ICAM1 NFKBIA	down	**
HOXA9_DN.V1_UP	0.0000000	0.0000011	0.7195128	-0.3892703	-2.079826	164	SGK3 PECAM1 MNDA SNX10 PTPRE THBD FYN SAMHD1 ST3GAL6 ZCCHC2 NCF2 AGTPBP1 FUCA1 FRAT1 IFI30 PAQR3 ZFYVE16 TFEC FBXL5 BST1 KLF4 COQ10B UHRF1BP1L LY96 HPSE CLK4 FCER1G AKIRIN1 TDRD7 FRY PHTF2 SERPINB8 MAP4K4 TYROBP OSTM1 TMEM251 PTGER4 GLIPR1 GPR183 ENTPD4 TNFRSF10B FOS KIAA0232 CD86 GALC ATXN1 FCGRT TOB1 STX12 CRY1 ACYP2 GPR18 PLAA SESN1 SLC35D2 VASH1 IER5 MS4A4A IFFO1 SCPEP1 ICAM3 THEMIS2 LPAR6	down	***
RB_P107_DN.V1_UP	0.0000002	0.0000063	0.6901325	0.4784325	2.070075	118	CDC45 PRIM2 E2F8 GTSE1 POLE MCM2 PRC1 CCNF COX6B2 GINS4 NCAPD2 WDR90 RPL39L PAQR4 FANCA SNCG MCM7 RRM2 WDHD1 CHAF1B LIG1 DNAJC9 ORC6 MAD2L1 IPO9 SAMD10 PML NAA40 EDN2 INCENP ASF1B POLE2 CENPH GMNN E2F1 DNA2 FEN1 CCNE1 COL1A1 TUBG1 COL1A2 POLD1 CENPK RPA1 MCM6 MCM5 HMCES TMEM45B CDH11 PRIM1 RFC5 BLVRB	up	***
STK33_SKM_UP	0.0000000	0.0000002	0.7614608	-0.3562349	-1.989859	235	NLRC4 KMO IL1A HMOX1 SLC12A6 CD101 OLR1 OSBPL11 SOWAHC CPEB2 IL1B FABP4 LPXN GPR65 MIR22HG THBD PID1 C5AR1 BCL2A1 NCF2 CD9 TRIB1 FGR CD36 ANXA1 SH2B3 PTPRM HBEGF HECW2 BTG2 KLF6 SLC7A11 RGCC CRK TFEC CD58 RHOB CYBRD1 PTPRO MPEG1 LY96 RIT1 CDKN1A CCL4 CD53 DUSP1 EMP3 CREBRF SGK1 RNF141 NECAP1 ARL5B CPEB4 TYROBP JUNB DUSP8 SKIL GLIPR1 GPR183 SUCNR1 FAM177A1 ZNF407 FOS BTBD7 NAPSB MILR1 CDC37L1 DUSP5 TGFB1I1 CD86 TMEM107 HINT3 STX12 NBEAL1 RGS2 EPB41L5 CALHM2 TFPI RTN1 CDKN1C TMOD2 TTLL7 STAM2 TLR10 NFKBIA	down	***
CSR_LATE_UP.V1_UP	0.0000545	0.0011453	0.5573322	0.4028577	1.786296	143	TRIP13 FOXM1 CHEK2 CCDC34 PBK ANLN TOMM34 NUF2 YEATS4 CDCA8 CDC6 UHRF1 UMPS MYBL2 EIF3B ZWINT CASP2 C19orf48 FANCA EEF1E1 CLSPN RRM2 MCM3 ACTL6A DCTPP1 RAD18 PPP5C KRT18 CDK1 BIRC5 DCBLD1 GMNN POLR3K FEN1 EZH2 PA2G4 ILF2 TUBG1 LMNB2 YIPF3 KIF22 DTYMK NOC2L POLD1 PSMD2 CDC7 ASB6 CKAP2 GINS3 PRMT5 FARSA PRIM1 SHCBP1 FARSB ZWILCH CDK5 CIAPIN1 MTHFD1 PAICS UBE2C	up	**
CSR_EARLY_UP.V1_UP	0.0001432	0.0021853	0.5188481	-0.3419629	-1.778811	134	USP12 KLF13 GATA2 NUP54 ZBTB2 MOB1B TBX2 EIF4A1 HBEGF CD33 KLF10 HLX ZNF697 SPRY2 PTPN12 MAP2K3 SNAI1 PLAUR REST ID3 ACTR3 DNTTIP2 ELK3 CCDC59 SMAD7 INHBA BCAR3 ETS1 DNAJA1 SPRY4 PTP4A1 UTP3 PHLPP2 TIMM22 AMD1 ITPRIPL2 SRP72 RIPK2 KPNA4 C21orf91 EHD4 FJX1 ZNF800 MSANTD3 UBE2N DDX21 TRMT10C SREK1IP1 PTGS2 YOD1 CBFB PNP ST3GAL1 FAM107B GNL2 EIF4A3 RNPS1 DIS3 MYO9B PTPN1 TNFRSF12A TOP1	down	**
TGFB_UP.V1_UP	0.0000276	0.0006529	0.5756103	-0.3306802	-1.763913	165	SMAD6 DLC1 TBX3 WNT4 RAPGEF2 RCOR1 BMPR2 PLEKHA1 IL1RL1 SLCO2A1 TRIB1 CLCF1 UBL3 ITGA5 ABCG1 KLF10 HLX RGCC PDGFA CASP5 RHOB SNAI1 KLF4 PXDC1 ID3 KLF7 ATF3 JAM2 ELK3 CYP26B1 KANK1 HCAR3 SGK1 JUN LTBP2 HRH1 JUNB FERMT2 SKIL NDST1 LMCD1 CDK17 PKIA WNT11 TFEB JMJD6 TAGLN ETS2 ANKLE2 TNFAIP8 LRP12 EPHA4 MAP3K4 JMJD1C CD1E EDN1 CYTH1 MMD FLT4 SPHK1 SPSB1 TBPL1	down	***
PRC2_EED_UP.V1_DN	0.0001179	0.0020343	0.5384341	0.3828890	1.732015	168	CA9 HELLS CDC45 MCM10 BUB1B PAGR1 ANKZF1 DBF4B PLK1 CDCA8 MCM2 MYBL2 ORC1 ACY1 AP1G2 MICALL2 TOP3B KIF23 QTRT1 FRS2 ODF2 POLA2 CLSPN LIPE RAD54L PCDHGA3 PHKG2 CHAF1B ABCB9 TRMT2A CAD FADS2 SYMPK GLE1 IDH2 ERCC2 BTBD2 INCENP APLP1 ASF1B EXOSC2 C1orf112 PACS1 TNK2 RECQL4 RANGAP1 SLC35C2 CHST3 TACC3 DLK2 PRMT7 LRRC20 POLD1 SLC26A1 TNS4 ZNF446 MCM5 SURF2	up	**
KRAS.KIDNEY_UP.V1_DN	0.0015533	0.0154517	0.4550599	0.4061562	1.696189	89	SLC9A3 B3GALT5 NPC1L1 ZDHHC8P1 SLC5A5 IGKV3D-15 CHRNG GPR35 TENM2 KLHDC8A SGK2 LILRB4 VILL LRRC31 CETP NPFFR1 CXCL10 SLC6A20 FOXA1 IFI44L LIPE MDFI EDN2 CXCL11 DDX51	up	*
RB_P130_DN.V1_UP	0.0021741	0.0205448	0.4317077	0.3896599	1.660137	101	HMGA2 SIM2 KIF20A CHCHD6 RACGAP1 AURKB CCNB2 SLC7A9 ORC1 B4GALT4 FAM220A RUVBL2 QTRT1 AURKA POLD2 ICA1 DCTPP1 FADS2 ANAPC5 CDK1 EXOSC2 BIRC5 ATP2A1 EFTUD2 PARS2 CRLF1 KIF22 RAD51D TK1 CASP7 SGSM3 CDC7 SULT1B1 ZNF428 RABEPK STMN3 POLR2I LSM4	up	*
WNT_UP.V1_UP	0.0007003	0.0082728	0.4772708	0.3789704	1.655777	133	CPS1 ENTPD2 HS3ST1 GRIN2D GALNT6 EYA2 UGT8 TFF3 STK36 LCN2 CHRNA7 AURKB DPYSL4 INSRR AP1G2 POLD2 IL12B KDELR2 THYN1 MST1R FNTB LTB4R HPS4 NF1 MYO5B FOXK1 ADAM28 RAD9A MC1R TSPO2 KCNC3 FXYD3 THRB DNAJB13 STRN4 CXCL1 CKMT2 CYP2S1 LANCL2 HTRA3 CKAP4 AP2S1	up	**
MYC_UP.V1_UP	0.0006325	0.0079692	0.4772708	0.3697610	1.639543	143	HP SLC29A4 TSFM SORD C12orf66 ECE2 METTL1 SLC27A2 C5orf46 NR2C2AP C19orf48 NLE1 QTRT1 EEF1E1 PUS7 B3GNTL1 SMYD5 DCTPP1 CAPS LRRC61 REPIN1 ALG3 PES1 CCDC78 ISOC2 UNG DGAT2 FAM86C1 PUS1 UBE3D GEMIN5 CGREF1 RRP9 NOL6 WDR83 VWA3B NOC4L EXOSC5 NEFH MMP16 WDR4 FARSB MICU1 VPS9D1	up	**
CAMP_UP.V1_DN	0.0001503	0.0021853	0.5188481	-0.3058875	-1.636899	175	LRRFIP1 INSIG1 MED4 NCF2 EPB41L3 ANXA1 ATP2B1 BZW1 SERINC1 GLS EIF4E SRSF2 AKT3 CLK1 ZMIZ1 TJP1 MYO15B TMBIM1 NFKB1 UBE2E2 PTPRC ID2 CCND2 PLEK MBD2 PINK1 GNAQ IL7R BACE1 SNN FOXN3 FRY CD160 RGS18 RAB31 MAP4K4 DNAJA1 MTMR9 MPZL3 CD83 IDS CELF2 PELI1 CALM1 FOSB PKIA TIMP2 TSC22D1 BAG6 SPOCK2 ETS2 PRDM8 SYT11 GEM RNF138 MIR155HG HSP90AA1 ESYT1 CCR9 HSPA8	down	**
BMI1_DN_MEL18_DN.V1_UP	0.0004710	0.0063579	0.4984931	-0.3167017	-1.600297	123	WEE1 IL1A TEK SIK1 FOSL1 CDH13 CDC42EP2 KCNN3 ZEB2 TNFRSF8 HBEGF ITGA5 TNIP3 SLC7A11 LCP1 ADRB2 SLC19A1 TFEC BST1 PLAUR KLF7 ATF3 INHBA ARL4A IL7R ANXA3 TGFB2 FAM189A1 C2CD2 APBB2 PODXL TNFRSF9 OGFRL1 GFPT2 EHD1 PIM1 TAGLN TIMP3 EDN1 TNFSF9 COL13A1 NRP2 PIEZO1 CSF2 GREM1 FJX1 FADS3 LHFPL2 HAS2 PIK3CG	down	**
PRC2_EZH2_UP.V1_DN	0.0025549	0.0219493	0.4317077	0.3546613	1.575425	146	HELLS CDH17 HJURP CDC45 MCM10 CENPF NPAS1 PSPH SCN3A DEPDC1 TTK AURKB ECT2 MCM2 CDC25A MYBL2 CDT1 HAUS5 HMMR KIF15 KNTC1 BUB1 PUS7 RAD54L LMNB1 MST1R OXTR DSCC1 LRRC61 SKP2 PSRC1 THOP1 APLP1 GNB1L DNA2 EZH2	up	*
DCA_UP.V1_UP	0.0035818	0.0282066	0.4317077	0.3624785	1.568367	118	NPC1L1 PTPRT CDC45 GRIN2D IGKV3D-15 EYA2 COLQ CABIN1 CATSPERB AURKB SIX1 ZNF117 CLCN2 AOC1 KREMEN2 TNNT2 CASP2 MDK KLHL3 GABRB2 MCTP2 BCAS4 GIPR ALG1L2 GDPD3 FMO6P LRFN3 ZSWIM1 NTN3 TYRO3 RAI1 TTLL3 TNS4 NRXN2 ANKRD1 CUBN INSL3 ZNF91 ADARB2 COPZ2 MIR600HG LPAR3 SARDH DNAL4 INO80B OVGP1	up	*
PRC2_EZH2_UP.V1_UP	0.0013660	0.0143425	0.4550599	-0.2991511	-1.563792	147	SLPI EREG TMEM100 KLF13 KCNA2 PRKG2 PTPRB BMP2 AATK FLVCR2 CDH13 MTMR10 IL1RL1 TRIB1 MCTP1 HBEGF ANPEP MALL RGCC PDGFA CDADC1 DUSP3 KIAA0513 KLF4 NES PAQR5 KLF11 RASL12 SLC14A1 KCTD12 OSTM1 DUSP8 IRF8 IDS GFPT2 PKIA FXYD6 OSGIN1 ATXN1 CCDC68 KYNU CLEC2B SLC35D2 OPN3 PAMR1 TTLL7 MEGF9 EDN1 COL13A1 NR3C2 CD70 CLIP1 NR4A2 CLEC4E SLC19A2 EYA3 YRDC OTUB2 FPR3	down	*
AKT_UP_MTOR_DN.V1_DN	0.0035154	0.0282066	0.4317077	0.3452975	1.547663	155	COL17A1 CPLX2 BDH1 PROM1 COIL JPH3 PKP1 IRS1 ACY1 MOCOS SMARCD3 KCNN4 POLM PUS7 ZNF112 POLD2 MSX1 CHAD SARS2 ASS1 CBY1 MGAT4B TULP3 HARS2 MERTK TYW1 STEAP1 PSAT1 KRBA1 DNAJA3 SLC37A4 COL5A2 CENPQ MSRB2 AGPAT5 CADM3 MCM6 PLEK2 UTP20 LANCL2 RTKN IL7 STAB1 CAP2 CDC42BPA BLVRB VPS33B GNA14 MTHFD1 KCNAB3 PARP2 ISYNA1 ZC3HC1 DPYD ZNF771 CES2 AP2B1 FMO3 TYMP RPS6KB2 MRPS6 CDPF1 SHMT1 TIPIN IL17RC	up	*
E2F1_UP.V1_UP	0.0046020	0.0347914	0.4070179	0.3402806	1.529182	162	MCM10 UBE2T PRIM2 MRPL46 E2F8 STIL AURKB E2F3 MCM4 TYMS PRC1 UQCC1 RND2 BUB1 TOP2A POLA2 WDHD1 CHAF1B LMNB1 SLC9A3R1 CHEK1 DCTPP1 CAD ERCC2 HSPBP1 PARP1 THOP1 DRC1 ARHGAP39 UCK2 PACS1 PHF12 DNA2 KIF2A FEN1 SSX2IP EZH2 TAF6 EIF6 SPEF1 DLGAP5 TK1 CASP7 PKP4	up	*
CSR_LATE_UP.V1_DN	0.0023479	0.0211314	0.4317077	-0.3009532	-1.514046	122	ACVRL1 SC5D HHEX IL1B CLEC3B INSIG1 BACH1 LONRF1 CDC42EP2 IDI1 HMGCR GAS6 STARD4 ADAM17 OLFML2A BTG2 MOB3C ANKRD29 DAAM2 DRAM1 VAMP5 PLCD1 DDX60L SFTPB PDE5A GYPC RASSF2 MSMO1 MME IRS2 SOD2 MRGPRF PAMR1 KIT FDFT1 LDLR C1orf52 C1orf115	down	*
TBK1.DF_UP	0.0010116	0.0112468	0.4550599	-0.2614934	-1.459393	243	IL1A HMOX1 SWAP70 SNX10 LPXN ADCY9 PID1 PLEKHF2 EML1 EOGT TEX2 KIAA0355 HBEGF CSGALNACT2 ANPEP PAQR3 SIRPA RB1 TMEM41B ZFYVE16 BTG3 PPP3CC CYBRD1 DUSP3 AGO3 SAP30BP PLAUR PXDC1 CDIP1 KLF11 DAB2 TMED5 STX3 ITPK1 NFKB1 RIT1 CXCL2 ATF3 UXS1 ARAP3 GCA TP53BP2 DEGS1 NRBF2 BTG1 EMP3 SERTAD2 VAMP3 CREM PKNOX1 PHTF2 SNAP23 PHF10 OSTM1 FERMT2 CD83 TRAK2 TNFRSF10B PELI1 RRAS RIN2 LSM6 DUSP5 MAP3K2 CCDC68 STX12 HSPA2 TNFAIP8 CGRRF1 OPN3 NT5C2 CDC42EP3 LRP12 TMEM184B RNF38 FEZ1 TRIM36 DCUN1D2 RABGEF1 TMEM50A CHIC2 TBPL1 FKBP1B ATP11B ENDOD1	down	*

C7 immunologic Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.2545135	-0.5757645	-3.016973	165	CXCL3 EREG IL1A DENND5A USP12 ADTRP IL1B RAPGEF2 OTUD1 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 PSMD5 IL23A STARD4 ATP2B1 PTS HECW2 PPP1R15B TNIP3 MAP3K8 PTX3 ADRB2 NFE2L2 TXN CASP5 EIF1B IL10 CSRNP1 STAT5A DUSP3 PLAUR DRAM1 NFKB1 CXCL2 ID2 CCL4 TAF9 DUSP1 PLEK INHBA TP53BP2 MAFF RASGEF1B KANK1 AREG RYBP NSMAF SOCS3 SERPINB8 JUN ARL5B STAT4 PLK3 PPP1R15A ELOVL7 CCR7 CD83 OSM REL CXCL5 GPRC5A DENND4A ACSL1 SNX9 PELI1 PTP4A1 HIVEP2 PIK3AP1 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 ETS2 CCL20 GEM ICAM1 LDLRAD4 IL18 ABL2 MIR155HG RIPK2 NLRP3 RND1 MAP3K4 HNRNPC NFKBIA EDN1 FNIP2 B3GNT2 TNFSF9 PMAIP1 PIM3 NAF1 EGR1 FJX1 DCUN1D3 MSANTD3 YRDC DNAJB4	down	***
GSE29618_BCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.2378967	-0.5520681	-2.930187	178	SLC31A2 HMOX1 DENND5A PECAM1 LTA4H FBP1 DPYSL2 MIR22HG PID1 HSD17B11 CD44 RTN3 MYD88 C5AR1 EPB41L3 TRIB1 PILRA LILRB3 RHOA MCTP1 HBEGF CD33 SLC7A7 BEST1 IFI30 PICALM ANXA5 PTX3 STOM CD93 TCF7L2 ATP6V1B2 FBXL5 ZMIZ1 SDCBP KIAA0513 CASP1 BST1 PTAFR KLF4 PLAUR ITM2B ZFAND5 CEBPA TPP1 COTL1 CXCL2 VIM HPSE TLR4 CAPZA2 PLEK GNAQ VAMP3 CTSS RAB31 TREM1 RHOG IFNGR1 GSTO1 GMFG ACSL1 ALDH3B1 RIN2 PEA15 ATP6V1A TSPAN14 ATP6V0C GNG5 SOD2 CCR1 RXRA SELPLG ARPC2 FKBP1A RTN1 RTN4 CDC42EP3 CEBPD TIAM1 NLRP3 UBE2D1 ULK2 DAPK1 CREG1 GIMAP4 WDFY3 GRPEL1 PPP2R3C CHP1 DUSP6 SVIL AOAH FTL NDFIP1 QSOX1	down	***
GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.1866510	-0.5574899	-2.922667	163	CXCL3 IL1A DENND5A USP12 ADTRP IL1B LRRC8C RAPGEF2 OTUD1 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 OTUD4 IL23A STARD4 ATP2B1 HECW2 PPP1R15B BTG2 TNIP3 MAP3K8 PTX3 ZNF697 ADRB2 TXN CASP5 EIF1B IL10 CSRNP1 STAT5A PLAUR DRAM1 NFKB1 CXCL2 ID2 CCL4 TAF9 DUSP1 PLEK INHBA TP53BP2 MAFF RASGEF1B KANK1 AREG IL6 RYBP SOCS3 SERPINB8 JUN ARL5B PLK3 PPP1R15A ELOVL7 CCR7 CD83 DDX5 REL DENND4A ACSL1 SNX9 PELI1 PTP4A1 NIPAL4 PIK3AP1 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 ETS2 CCL20 GEM ICAM1 LDLRAD4 IL18 ABL2 MIR155HG RIPK2 NLRP3 RND1 MAP3K4 HNRNPC NFKBIA EDN1 FNIP2 B3GNT2 PMAIP1 PIM3 NAF1 EGR1 FJX1 DCUN1D3 MSANTD3 YRDC DNAJB4	down	***
GSE29618_MONOCYTE_VS_MDC_UP	0.0000000	0.0000000	1.2295041	-0.5490198	-2.914008	178	SIRPB1 SLC31A2 HMOX1 ABHD5 FCN1 LTA4H CYP27A1 MIR22HG EGR2 CD44 BACH1 RTN3 C5AR1 MKNK1 MARCO BCL2A1 NCF2 LAMP1 SLC11A1 PILRA LILRB3 FGR CD36 PLA2G7 SLC7A7 BEST1 ASAH1 EIF1 BTG2 IFI30 ADIPOR1 CD93 TCF7L2 FBXL5 CFD SDCBP KIAA0513 BST1 ITM2B DRAM1 KLF7 CTSD RIT1 RBMS1 CXCL2 HPSE TLR4 FCER1G EVI2A MBD2 LIN7A NINJ1 HCAR3 FRY CTSS PGD MAP4K4 TYROBP TREM1 GMFG PTGER2 ACSL1 SPRY4 PELI1 PNPLA2 TNFSF13 RIN2 BIN2 CR1 FXYD6 IRS2 ATXN1 APLP2 SOD2 CCR1 RXRA BNIP3L CDC42EP3 TIAM1 GIMAP5 NLRP3 UBE2D1 IFFO1 SCPEP1 S100A4 GLUL NFKBIA MARC1 LDLR CREG1 DMXL2 EGR1 DUSP6 AOAH FTL S100A8 FPR1	down	***
GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.1953445	-0.5533809	-2.901627	166	CXCL3 EREG IL1A DENND5A USP12 ADTRP IL1B RAPGEF2 OTUD1 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 PSMD5 IL23A STARD4 CLCF1 PTS HECW2 PPP1R15B BTG2 TNIP3 MAP3K8 PTX3 NR4A1 RGCC NFE2L2 ARHGEF2 BTG3 TFRC TXN CASP5 EIF1B IL10 CSRNP1 STAT5A PLAUR NFKB1 CXCL2 ID2 CCL4 DUSP1 CCDC59 PLEK INHBA HES1 TP53BP2 MAFF AREG IL6 RYBP SOCS3 SERPINB8 JUN ARL5B PLK3 PPP1R15A WTAP PTGER4 CCR7 CD83 DDX5 REL CXCL5 DENND4A ACSL1 PELI1 PTP4A1 HIVEP2 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 PDE4B ETS2 CCL20 ICAM1 IL18 MIR155HG NBN LMOD1 RIPK2 NLRP3 UBE2D1 RND1 MAP3K4 HNRNPC NFKBIA EDN1 B3GNT2 PIM3 NAF1 EGR1 NR4A2 DCUN1D3 MSANTD3 YRDC DNAJB4	down	***
GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.2210538	-0.5428203	-2.886017	180	SLC31A2 ABHD5 MNDA FBP1 SNX10 PTPRE COQ2 CCDC88A BACH1 CORO1C FLVCR2 SLC15A3 TBC1D2 MANBA NCF2 SLC11A1 FAM49A IGSF6 PILRA LILRB3 FGR CD36 SH2B3 MCTP1 CD33 SLC7A7 ASAH1 CLEC7A IFI30 PICALM SIRPA CD93 GRN ATP6V1B2 ZMIZ1 DUSP3 SDCBP CASP1 PTAFR CPVL ZFAND5 STX3 TPP1 PLBD1 LY96 ATG7 LAPTM5 KCNMB1 GCA FKBP15 GLB1 HEXB VAMP3 PGD MTMR14 KCTD12 HK3 ATP6V0B IFNGR1 CSTA TBC1D12 STX7 TNFRSF10B ACSL1 ATP6V0D1 RHOQ TNFSF13 RIN2 TIMP2 PEA15 ATP6V1A APLP2 LGALS3 EXOC1 CCR1 STX12 RXRA PDLIM5 RTN1 SEMA4A CDC42EP3 CEBPD NLRP3 UBE2D1 SCPEP1 DAPK1 GLUL SIGLEC9 CREG1 FEZ2 DMXL2 CSF2RB CTSH DUSP6 FTL FPR1 PTGS1	down	***
GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.2039752	-0.5402401	-2.867408	178	SLC31A2 HMOX1 ABHD5 FCN1 MNDA FBP1 PTPRE COQ2 BACH1 CORO1C FLVCR2 C5AR1 SLC15A3 TBC1D2 MANBA NCF2 SLC11A1 FAM49A IGSF6 PILRA LILRB3 FGR CD36 MCTP1 CD33 SLC7A7 ASAH1 CLEC7A IFI30 SIRPA CD93 GRN CST3 ZMIZ1 DUSP3 SDCBP PTAFR KLF4 CPVL PLBD1 LY96 ATG7 LAPTM5 KCNMB1 FCER1G GCA HEXB HCK VAMP3 CTSS PGD MTMR14 RAB31 KCTD12 TYROBP IFNGR1 CSTA TBC1D12 IRF8 TNFRSF10B ACSL1 PLCG2 TNFSF13 RIN2 TIMP2 ATP6V1A APLP2 LGALS3 EXOC1 CCR1 ADPGK STX12 CLCN6 RXRA RTN1 SEMA4A CDC42EP3 CEBPD DAPK1 GLUL SIGLEC9 CREG1 FEZ2 LYZ DMXL2 CSF2RB CTSH DUSP6 FTL S100A8 FPR1 PTGS1 QSOX1 PPFIA1 MFSD1 CAPZA1	down	***
GSE29618_MONOCYTE_VS_PDC_UP	0.0000000	0.0000000	1.1866510	-0.5414862	-2.860342	174	SLC31A2 HMOX1 PTP4A2 CD44 LY86 C5AR1 P2RY13 MARCO BCL2A1 NCF2 IL1RN EPB41L3 TRIB1 PILRA LILRB3 FGR IER2 ANXA1 DPEP2 PLA2G7 HBEGF CD33 SLC7A7 BEST1 ASAH1 ENTPD1 CLEC7A CSRP1 SIRPA CD93 SPI1 TCF7L2 CD58 RHOB FBXL5 EVI2B TLE4 SDCBP CASP1 BST1 TNFSF12 YBX3 ITM2B KLF11 CEBPA PLBD1 ITPK1 ITGAX PTPRC HPSE TLR4 MBD2 SLC6A6 LIN7A ARHGDIB HCK HCAR3 CTSS SEC14L1 RAB31 TYROBP TREM1 GMFG ACSL1 PELI1 ALDH3B1 RIN2 TIMP2 GSAP CD1D TSPAN14 CD86 IRS2 APLP2 SOD2 LGALS3 TSPO RXRA BNIP3L CDC42EP3 NLRP3 UBE2D1 MEGF9 SCPEP1 S100A4 LYST HEBP1 CREG1 WDFY3	down	***
GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.1601796	-0.5353948	-2.844375	179	SLC31A2 ABHD5 FCN1 MNDA FBP1 SNX10 PTPRE COQ2 CORO1C FLVCR2 C5AR1 SLC15A3 TBC1D2 MANBA NCF2 SLC11A1 FAM49A IGSF6 PILRA LILRB3 FGR CD36 SH2B3 SLC7A7 ASAH1 CLEC7A IFI30 KLF10 SIRPA CD93 GRN SPI1 ZMIZ1 DUSP3 SDCBP CASP1 YBX3 KLF4 TPP1 PLBD1 LY96 KCNMB1 FCER1G GCA FKBP15 GLB1 HEXB HCK VAMP3 CTSS PGD MTMR14 RAB31 KCTD12 HK3 ATP6V0B IFNGR1 CSTA TBC1D12 STX7 IRF8 TNFRSF10B PLCG2 FOS ATP6V0D1 TNFSF13 RIN2 TIMP2 ATP6V1A LGALS3 EXOC1 CCR1 STX12 NPTN CLCN6 RXRA PDLIM5 SEMA4A CDC42EP3 CEBPD UBE2D1 MEGF9 SCPEP1 DAPK1 GLUL GLRX2 SIGLEC9 CREG1 FEZ2 LYZ DMXL2 CSF2RB CTSH DUSP6 FTL S100A8 FPR1 PTGS1 PPFIA1 MFSD1 CAPZA1	down	***
GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP	0.0000000	0.0000000	1.1601796	-0.5351173	-2.842900	179	SIRPB1 SASH1 HMOX1 FCN1 MCOLN1 ASGR1 LTA4H CYP27A1 CD44 RTN3 C5AR1 MKNK1 MARCO MANBA NCF2 GIMAP6 FUCA1 LAMP1 SLC11A1 PILRA RHOA CD36 DPEP2 PLA2G7 SLC7A7 BEST1 ASAH1 NAAA CLEC7A BTG2 SERINC1 PTX3 LAIR1 TCF7L2 ATP6V1B2 FBXL5 SDCBP KIAA0513 BST1 ITM2B DRAM1 GRK5 KLF7 PLBD1 CTSD TMBIM1 RBMS1 CXCL2 ARAP3 DUSP1 EVI2A MBD2 CLIP4 LIN7A NINJ1 HCAR3 VAMP3 FRY CTSS PGD UTRN TREM1 SNX2 PTGER2 ACSL1 AGFG1 PELI1 KLF2 RIN2 BIN2 CR1 FXYD6 TSPAN14 ATXN1 APLP2 SOD2 LGALS3 ICAM1 BNIP3L CDC42EP3 GIMAP5 UBE2D1 IFFO1 SCPEP1 GLUL NFKBIA MARC1 THEMIS2 CREG1 GIMAP4 DMXL2 EGR1 DUSP6 LHFPL2 FTL S100A8	down	***
GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP	0.0000000	0.0000000	1.1421912	-0.5285625	-2.800069	175	PHACTR1 USP12 PPARG DCSTAMP MIR22HG PTPRE CLDND1 THBD RRN3P2 LPL EGR2 GFOD1 ST3GAL6 FOSL1 GPCPD1 TBC1D7 TBC1D2 NR3C1 TRIB1 CNST RRAGC B3GNT5 HBEGF SGMS2 HECW2 LINC01010 ZBTB21 KLF10 NR4A1 RGCC SPRY2 CRTAM ZFYVE16 TFRC TXN TMEM38B ATP6V1B2 CSRNP1 MOAP1 DUSP3 ADO ACSL3 PLAUR COQ10B TNFSF15 STX3 MAFG SPAG9 RIT1 CDKN1A CXCL2 ATF3 ZBTB43 TAF9 DUSP1 INHBA EFR3A RASGEF1B MMP19 NRROS ETF1 RYBP NSMAF SGK1 JUN SH3BP5 HIC1 TMEM251 FERMT2 DDX5 KBTBD8 HOMER1 GPRC5A SNX9 SLC3A2 PTP4A1 TGIF1 OSGIN1 DUSP5 COL15A1 TMEM70 GNA13 ETS2 GEM ABL2 HAVCR2 TMEM217 JMJD1C MAFK EDN1 FNIP2	down	***
GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN	0.0000000	0.0000000	1.0768682	-0.5348954	-2.798141	158	CXCL3 KMO IL1A DENND5A ZC3H12C IL1B SNX10 RAPGEF2 PLEKHF2 CCRL2 AQP9 SFR1 BCL2A1 PSMD5 ATF7IP2 IL23A CLCF1 PPP1R15B TNIP3 MAP3K8 RNF144B KLF6 PTX3 ARHGEF2 BTG3 IL10 CSRNP1 STAT5A TBC1D9 LINC00528 PPM1K PLAUR DRAM1 CLIC4 CXCL2 IRAK2 ID2 CCL4 CCSER2 PLEK TP53BP2 NINJ1 HCAR3 FLT1 IL6 SYNPO2 SOCS3 ARL5B PLK3 PPP1R15A WTAP ELOVL7 CCR7 CD83 OSM TNFRSF9 DENND4A ACSL1 PELI1 PTP4A1 SAV1 EHD1 TEX14 GPR84 PHF19 SOD2 ADORA2A-AS1 ETS2 CCL20 ICAM1 IL18 TNFAIP8 MIR155HG NBN GIMAP5 RIPK2 NLRP3 TRAF1 TTC32 MAP3K4 HNRNPC NFKBIA ADORA2A PMAIP1 CSF2 PIM3 NAF1 CLEC4E DCUN1D3 ZFP36 MSANTD3 YRDC RCSD1 CSF3 GJB2 CFLAR PTGS2 HIVEP1 NFKBIZ DUSP2 RNF19B	down	***
GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.0959293	-0.5297102	-2.773177	162	CXCL3 IL1A DENND5A USP12 ADTRP IL1B RAPGEF2 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 PSMD5 IL23A STARD4 CLCF1 PTS HECW2 PPP1R15B BTG2 TNIP3 MAP3K8 PTX3 RGCC BTG3 TFRC TXN EIF1B IL10 CSRNP1 STAT5A PLAUR DRAM1 CDKN1A CXCL2 ID2 CCL4 CCSER2 DUSP1 PLEK INHBA HES1 TP53BP2 MAFF AREG IL6 RYBP SYNPO2 SOCS3 SERPINB8 ARL5B PLK3 PPP1R15A WTAP PTGER4 CCR7 CD83 DDX5 REL FAM177A1 DENND4A ACSL1 PELI1 PTP4A1 HIVEP2 FOXO3 RIN2 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 ETS2 ICAM1 IL18 MIR155HG RIPK2 NLRP3 UBE2D1 RND1 MAP3K4 HNRNPC NFKBIA EDN1 B3GNT2	down	***
GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN	0.0000000	0.0000000	1.1330899	-0.5242638	-2.763489	172	SLC31A2 HMOX1 FCN1 PECAM1 SNX10 COQ2 LMO2 CORO1C C5AR1 SLC15A3 MARCO NCF2 IL1RN SLC11A1 EPB41L3 FAM49A IGSF6 PILRA LILRB3 CD36 SPG21 SLC7A7 ASAH1 GM2A CLEC7A IFI30 ANPEP HLX SIRPA CD93 GRN TFEC ATP6V1B2 CST3 CFD DUSP3 SDCBP KLF4 PLAUR GAA CEBPA TPP1 CLIC4 CTSD ERP44 ITGAX FCER1G GCA DSE HEXB HCK RAB31 KCTD12 HK3 ATP6V0B TYROBP IFNGR1 CSTA IRF8 OGFRL1 ACSL1 PLCG2 RHOQ TNFSF13 ALDH3B1 CD74 RIN2 TIMP2 PEA15 MILR1 CD86 APLP2 LGALS3 CCR1 FCGRT KYNU RXRA CEBPD NLRP3 ALDH2 DAPK1	down	***
GSE11057_CD4_CENT_MEM_VS_PBMC_DN	0.0000000	0.0000000	1.1330899	-0.5239418	-2.761791	172	SIRPB1 SLC31A2 SIDT2 ABHD5 HVCN1 LTA4H FBP1 DPYSL2 PTPRE OSCAR TMEM170B CCDC88A BACH1 GFOD1 MYD88 SLC15A3 CD9 EPB41L3 IGSF6 LILRB3 NCEH1 MAN2B1 B3GNT5 MCTP1 SLC7A7 ARSB ASAH1 RASGRP4 RNF144B PICALM RB1 CES1 SRGN SPI1 ADAMTSL4 FBXL5 CFD DUSP3 KIAA0513 PIP5K1B PTAFR TNFSF15 DRAM1 CEBPA FAM49B KCNMB1 TLR4 TM6SF1 PLEK TM9SF2 PRCP FMNL2 CD160 SNAP23 CTSZ SNX2 OGFRL1 LGALS2 WDFY4 ACSL1 RHOQ TNFSF13 DGKG CPA3 SORT1 TFEB FPR2 ATP6V1A PDLIM1 APLP2 MEIS1 FCGRT RXRA BMP2K ITPRIPL2 RTN1 SEMA4A SCPEP1 CD19	down	***
GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP	0.0000000	0.0000000	1.0959293	-0.5243219	-2.747417	165	IL1A USP12 ADTRP DCSTAMP RAPGEF2 MIR22HG CCRL2 ST3GAL6 NEDD4L FOSL1 TBC1D7 SFR1 IL23A STARD4 CLCF1 PTS HBEGF HECW2 PPP1R15B MAP3K8 KLF10 KLF6 NR4A1 RGCC SPRY2 TFRC TXN ATP6V1H TMEM38B IL10 CSRNP1 MOAP1 ACSL3 PLAUR COQ10B TNFSF15 STX3 SPAG9 RIT1 CDKN1A CXCL2 ID2 LBH DUSP1 CCDC59 INHBA HES1 TP53BP2 RASGEF1B NRROS FLT1 IL6 RYBP SYNPO2 NSMAF SGK1 PHACTR2 SOCS3 JUN ARL5B PLK3 TMEM251 PTGER4 FERMT2 CCR7 HOMER1 GPRC5A DENND4A SNX9 SLC3A2 PTP4A1 SAV1 OSGIN1 DUSP5 PIM1 ADORA2A-AS1 ETS2 GEM IL18 ABL2 MIR155HG RIPK2 FBXO30 NLRP3 MAFK EDN1 FNIP2 B3GNT2 PMAIP1 RABGEF1 PIM3 EGR1 NR4A2 SLC19A2 OSGIN2 HES4 SLC38A2 MSANTD3 DNAJB4	down	***
GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN	0.0000000	0.0000000	1.1421912	-0.5160808	-2.743850	180	FBP1 CAT DPYSL2 PTPRE RCOR1 LMO2 SAMHD1 FCER1A ST3GAL6 MYD88 CLEC10A APIP P2RY13 CD1C IL1RN IGSF6 ANXA1 EIF4A1 SH2B3 MCTP1 CD33 LMNA CLEC7A CSGALNACT2 KLF10 SIRPA RGCC GRN MCL1 CST3 TIPARP ARRB1 DUSP3 PPT1 AHNAK CASP1 LIMS1 KLF4 CPVL STX3 PLBD1 COTL1 ITGAX ATF3 VIM ID2 CD302 FCER1G GNAQ RUFY3 HEXB RAB31 KCTD12 TYROBP CSTA RCAN1 PSTPIP2 OGFRL1 LGALS2 CST7 TNFSF13 ATG3 SORT1 PEA15 CD1D CD86 GNG5 FCGRT TOB1 ETS2 ICAM1 LDLRAD4 IL18 CPQ FKBP1A RTN1 SEMA4A RTN4 CEBPD ALDH2 ACTB S100A4 DAPK1 CD1E CREG1 RNH1 GRPEL1 CACNA2D3 CHP1 TMEM43 AOAH NDFIP1 ATP1B1	down	***
GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP	0.0000000	0.0000000	1.1239150	-0.5165242	-2.741532	178	SLC31A2 HMOX1 FCN1 LTA4H PTP4A2 PID1 HSD17B11 CD44 FLVCR2 C5AR1 NCF2 IL1RN EPB41L3 IGSF6 TRIB1 PILRA LILRB3 FGR DPEP2 SPG21 ASAP1 HBEGF CD33 SLC7A7 BEST1 ASAH1 ENTPD1 CLEC7A IFI30 PICALM SIRPA CD93 TCF7L2 FBXL5 PTPN12 ARRB1 KIAA0513 CASP1 YBX3 ITM2B KLF11 CEBPA DENND3 PLBD1 TMBIM1 HPSE ARAP3 EVI2A LIN7A HCK HCAR3 SGK1 CTSS TREM1 SNX2 GMFG PTGER2 SERPINB6 RALB PPM1F ACSL1 AGFG1 PELI1 TNFSF13 ATG3 ALDH3B1 RIN2 CD1D TGIF1 CD86 APLP2 SOD2 RXRA RTN1 CDC42EP3 CEBPD NLRP3 UBE2D1 MEGF9 SCPEP1 ICAM3 LYST CREG1 WDFY3	down	***
GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN	0.0000000	0.0000000	1.1239150	-0.5106911	-2.723400	182	SIRPB1 SLC31A2 HMOX1 MIR22HG PID1 RCOR1 ST3GAL6 FLVCR2 C5AR1 STX11 IL1RN TRIB1 PILRA LILRB3 EIF4A1 MCTP1 HBEGF LMNA EMILIN2 KLF10 SIRPA RGCC GRN MCL1 CD58 CST3 FBXL5 ARRB1 AHNAK SDCBP KIAA0513 BST1 TNFSF12 PLAUR ITM2B GAA CEBPA CTSD ATF3 VIM HPSE ID2 CD302 ARAP3 EVI2A GNAQ LIN7A HEXB HCAR3 SGK1 PHACTR2 PGD TYROBP TREM1 PTGER2 OGFRL1 LGALS2 ACSL1 TNFSF13 ALDH3B1 SORT1 TIMP2 CD86 GABARAPL1 CCR1 FCGRT RXRA ICAM1 CPQ FKBP1A RTN1 SEMA4A CDC42EP3 CEBPD TIAM1 NLRP3 ALDH2 UBE2D1 ULK2 DAPK1 SIGLEC9 CREG1 WDFY3 DUSP6 AOAH FTL ZYX FPR1 NDFIP1	down	***
GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP	0.0000000	0.0000000	1.0768682	-0.5184900	-2.716858	165	CXCL3 PHACTR1 PPARG DCSTAMP P2RY1 MIR22HG INSIG1 LPL EGR2 CCRL2 GFOD1 ST3GAL6 CORO1C NEDD4L FOSL1 GPCPD1 TBC1D7 TBC1D2 TRIB1 EIF4A1 B3GNT5 SGMS2 HECW2 LINC01010 ZBTB21 KLF10 EIF4E CRTAM ZFYVE16 TXN TMEM38B TUBB6 FABP5 CSRNP1 NRARP MOAP1 DUSP3 ADO ACSL3 DAB2 TNFSF15 SPAG9 RIT1 CDKN1A CXCL2 M6PR ZBTB43 TAF9 DUSP1 INHBA UBASH3B RASGEF1B MMP19 ETF1 BCAR3 NSMAF SGK1 JUN SH3BP5 HIC1 TMEM251 FERMT2 KBTBD8 HOMER1 GPRC5A SNX9 SLC3A2 ADNP2 AKIRIN2 DUSP5 COL15A1 TMEM70 GNA13 ETS2 CCL20 GEM ABL2 CDC42EP3 HAVCR2 TMEM217 JMJD1C EDN1 FNIP2	down	***
GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN	0.0000000	0.0000000	1.0672100	-0.5151273	-2.711172	169	CXCL3 IL1A DENND5A IL1B RAPGEF2 PLEKHF2 AQP9 QKI SFR1 STX11 BCL2A1 PSMD5 EPB41L3 FAM49A IGSF6 PILRA IL23A CLCF1 ADA PPP1R15B MTF1 TNIP3 MAP3K8 RNF144B PTX3 NFE2L2 EPM2AIP1 BTG3 CASP5 EIF1B IL10 STAT5A ARRB1 LINC00528 BIRC2 DRAM1 CLIC4 NFKB1 CXCL2 IRAK2 ID2 CCL4 PNRC1 HCK HCAR3 IL6 SYNPO2 SOCS3 OASL SERPINB8 ARL5B PLK3 DNAJA1 CD83 TNFRSF9 TNFRSF10B DENND4A ACSL1 PELI1 HIVEP2 RIN2 PIK3AP1 AZIN1 SAV1 EHD1 NAB1 GPR84 KCNA3 SOD2 TAGAP ADORA2A-AS1 PDE4B CCL20 ICAM1 IL18 TNFAIP8 MIR155HG NBN IER5 TAB2 GIMAP5 RIPK2 NLRP3 TRAF1 RND1 HNRNPC NFKBIA MCOLN2 SAMSN1 LDLR PMAIP1 FNBP1 PIM3	down	***
GSE11057_PBMC_VS_MEM_CD4_TCELL_UP	0.0000000	0.0000000	1.0574636	-0.5146845	-2.696917	165	SIRPB1 SLC31A2 CD300LF HMOX1 SWAP70 ASGR1 HVCN1 LTA4H CYP27A1 TUBB1 OSCAR TMEM170B CCDC88A FCER1A C5AR1 SLC15A3 P2RY13 CD1C IL1RN TET2 EPB41L3 FAM49A IGSF6 LILRB3 ZEB2 TNFRSF8 PLA2G7 B3GNT5 SIRPB2 SLC7A7 SGMS2 ASAH1 IFI30 RNF144B HDC ANPEP PTX3 CES1 TFEC SRGN SPI1 ARL11 CYBRD1 BST1 SLC46A2 PIP5K1B PTAFR CEBPA TLR4 TM6SF1 CD300LB CD8B RBP7 FMNL2 CD160 CTSS RAB31 HK3 TREM1 LPCAT2 CXCL5 LGALS2 WDFY4 SORT1 TCF4 FPR2 CD86 CCR1 FCGRT KYNU RXRA BMP2K IL18 ITPRIPL2 RTN1 SCPEP1 CD19 LYST CACNA2D3 FCRL1 ATP6V0A1 DUSP6 CLEC4E AOAH NFAM1 PTGS1 GNG11	down	***
GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP	0.0000000	0.0000000	1.0768682	-0.5162300	-2.693554	168	SIRPB1 CXCL3 EREG CD52 FCN1 OLR1 ASGR1 PPARG GLIPR2 IL1B LTA4H PTP4A2 PTPRE MBOAT2 SIK1 LPL CCRL2 PRAM1 AQP9 CLEC10A ARL8B MARCO BCL2A1 CD1C IL1RN FRAT1 FGR EDEM1 DPEP2 ADA SGMS2 TNIP3 LITAF CSGALNACT2 ZNF697 NDEL1 SLC25A37 ZMIZ1 MAP2K3 FABP5 ITPRIP SLC46A2 PLAUR STK17B ITGAX CXCL2 SELL MMP19 ETF1 S1PR4 HCAR3 FRY AREG CD48 TREM1 CSTA WTAP GPR183 OSM PTGER2 MALT1 GRASP CXCL5 TNFRSF10B LGALS2 TAGLN2	down	***
GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP	0.0000000	0.0000000	1.2295041	0.5960907	2.679134	178	FOXM1 KIF20A CDC45 TICRR PARPBP MCM10 BUB1B NEK2 CENPF MND1 PBK KIF18B DEPDC1 PIF1 TTK CDCA2 RACGAP1 E2F8 GTSE1 ANLN POLE ASPM STIL PLK1 NUF2 AURKB CENPA ECT2 CDC6 TPX2 CCNB2 UHRF1 MYBL2 ORC1 CCNF DTL MUC20 CCT2 SPDL1 ITGA2 MELK HMMR EXO1 KIF23 CEP55 MKI67 BUB1 AUNIP TOP2A AURKA EME1 CLSPN RRM2 CDCA5 PASK FANCD2 MCM3 CDC25C LIG1 CHEK1 MAD2L1 CKAP2L RAD51AP1 SPC24 BRIP1 CCDC138 PSRC1 INCENP KNSTRN CKS1B NCAPG2 CBX5 CDK1 FAM221A CENPH BIRC5 FAM114A1 NCAPG DNA2 KIF2A PSAT1 FEN1 NUP205 SPAG5 CENPP NMRAL1 TACC3 KIF22 TK1 ESCO2 KIF20B CENPK CKAP5 CENPM MCM6 CKAP2 PRSS16 CCNA2 PRIM1 PRR11 SHCBP1 RFC5 RAD51 ZWILCH ARHGAP11A NDUFS8 CPOX MXD3 SMC2 SYNRG CENPE PFDN4 UBE2C MRPL20 E2F7 NUP93 KIF24	up	***
GSE10325_CD4_TCELL_VS_MYELOID_DN	0.0000000	0.0000000	1.0476265	-0.5108978	-2.677075	165	SLC31A2 KMO SIDT2 TSPAN4 OSBPL11 HHEX LTA4H SNX10 SLC6A12 FIG4 LYL1 LY86 LMO2 CCDC88A GFOD1 CORO1C AQP9 MYD88 SLC15A3 P2RY13 CD1C SLC11A1 FAM49A TRIB1 LILRB3 FGR SLC7A7 ENTPD1 GM2A CLEC7A IFI30 SIRPA TUBB6 MSR1 MAP2K3 TBC1D9 YBX3 PLAUR DENND3 CLIC4 CDKN1A ITGAX KCNMB1 PLEK DSE HEXB HCK PRCP RNF141 MTMR14 RAB31 STX7 IRF8 PLCG2 RHOQ TNFSF13 DGKG RIN2 IRF5 PEA15 CD1D CBFA2T3 CD86 APLP2 CCR1 KYNU RGS2 RXRA ICAM1 OPN3 CDKN1C ALDH2 MEGF9 SCPEP1 METTL7A LYST P2RX1 THEMIS2	down	***
GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN	0.0000000	0.0000000	1.0768682	-0.5018223	-2.668408	185	SOWAHC ZC3H12C IL1B FABP4 CLDND1 BMP2 EGR2 OTUD1 CCRL2 CITED2 CDC42EP2 STX11 BCL2A1 IER2 CCNL1 SDE2 BTG2 MAP3K8 PICALM KLF6 NDEL1 SPRY2 SRGN ARHGEF2 MCL1 TIPARP IL10 CSRNP1 TLE4 FOXO1 ACSL3 PLAUR ID3 ZFAND5 KLF7 P2RY2 ATF3 VIM C9orf72 ID2 CCL4 PNRC1 FRMD4A DUSP1 PLEK SPRYD7 USP16 RASGEF1B NRROS RBM39 ETF1 SLC25A25 RYBP SGK1 ETV3 JUN MTMR14 KCTD12 HSPA1B RAPGEF1 DHX15 SKIL IFRD1 CD83 DDX5 OSM MALT1 ATL2 REL FOS CDK17 MAPK8 EHD1 TGIF1 DUSP5 PIM1 PLSCR4 GPR84 SOD2 TOB1 GTF2B GEM ICAM1 IER5 RIPK2 PTCH1 MEX3C TNFSF9 DNAJA2 MAN1C1 RABGEF1 HERPUD1 ZNF800 CLEC4E SLC38A2 ZNF654 DNAJB4 CD69 WDR47 BCL10 TRIM13 IRF1	down	***
GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN	0.0000000	0.0000000	1.0672100	-0.5026107	-2.665189	181	SLC31A2 HMOX1 MCOLN1 ASGR1 PECAM1 FBP1 PTPRE ST3GAL6 FLVCR2 C5AR1 TBC1D2 MARCO NCF2 IL1RN LAMP1 SLC11A1 EPB41L3 IGSF6 PILRA LILRB3 CD36 SPG21 SLC7A7 BEST1 CLEC7A ITGA5 ANPEP SIRPA CD93 TCF7L2 ATP6V1B2 CST3 ZMIZ1 CFD SDCBP KIAA0513 KLF4 PLAUR ZCCHC24 GAA CEBPA CTSD ATG7 P2RY2 KCNMB1 HPSE FCER1G GNAQ HEXB VAMP3 RAB31 KCTD12 HK3 TYROBP RHOG IFNGR1 PSTPIP2 CAP1 ALDH3B1 RIN2 MILR1 GALC APLP2 LGALS3 DOK2 FCGRT TSPO ETS2 RXRA ARRB2 RTN4 NLRP3 ALDH2 ACTB S100A4 DAPK1 GLUL HEBP1 CREG1 LPAR6 WDFY3 FEZ2 DMXL2	down	***
GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP	0.0000000	0.0000000	1.1953445	0.5893013	2.643505	173	HJURP KCNK5 PARPBP MCM10 GMDS BDH1 GPT2 ELOVL6 CHEK2 BUB1B CCNB1 UBE2T KIF18B NDC80 PIF1 IFI27L1 DEPDC1B CDCA7 TTK CDCA2 E2F8 SLC27A2 ANLN ASPM NUF2 YEATS4 AURKB ECT2 CDC6 SFXN1 TPX2 RBBP8 TYMS CDC25A PRC1 DTL XPOT MELK EXO1 MKI67 KIF15 BUB1 TOP2A CENPL AURKA VANGL1 POLA2 SAE1 KIF2C POC1A RAD54L KIF11 CHEK1 ORC6 MAD2L1 CENPO SPC24 INPP4B MBOAT1 MNAT1 THOP1 CKS1B TMEM106C ASF1B CDK1 UCK2 BIRC5 TESC PSAT1 EZH2 SPAG5 DIAPH3 CCNE1 DLGAP5 TACC3 LMNB2 KIF22 TMEM237 DTYMK GINS2 TCEA1 LRRC20 SAP30 RNF187 LIMA1 FAF1 MCM6 MCM5 WDYHV1 ALG8 SUV39H2 CCNA2 PRIM1 DCPS BLVRB RAD51	up	***
GSE11057_CD4_EFF_MEM_VS_PBMC_DN	0.0000000	0.0000000	1.0276699	-0.4961729	-2.616151	173	SLC31A2 CD300LF MS4A7 HVCN1 LTA4H CAT PTPRE TMEM170B CCDC88A GFOD1 CORO1C AQP9 SLC15A3 MEF2A CD9 TET2 EPB41L3 LILRB3 ACER3 TNFRSF8 B3GNT5 SLC7A7 ARSB ASAH1 GNGT2 SRGN SPI1 ADAMTSL4 ATP6V1B2 FBXL5 CFD SDCBP KIAA0513 PIP5K1B TPP1 ITGAX C9orf72 TLR4 TM6SF1 CD300C PLEK SNN PRCP FMNL2 CD160 PGD SNAP23 RGS18 HK3 CTSZ TREM1 STX7 LGALS2 WDFY4 ACSL1 RHOQ TNFSF13 CD74 SORT1 TCF4 PEA15 NAPSB ATP6V1A PDLIM1 APLP2 RXRA BMP2K BNIP3L RTN1 SCPEP1 DAPK1 SIGLEC9 ARPC5 LYST CREG1 LYZ ATP6V0A1 DUSP6 AOAH FTL PLXDC2 NFAM1 PTGS1 MFSD1 DAPP1	down	***
GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN	0.0000000	0.0000000	1.0175448	-0.4928836	-2.598808	173	IL1A DENND5A IL1B SNX10 RAPGEF2 PLEKHF2 AQP9 QKI SFR1 STX11 BCL2A1 PSMD5 FAM49A PILRA IL23A CLCF1 ADA PPP1R15B MTF1 TNIP3 MAP3K8 RNF144B PTX3 TMEM123 NFE2L2 EPM2AIP1 BTG3 TCF7L2 EIF1B IL10 STAT5A LINC00528 BIRC2 PPM1K PTAFR DRAM1 CLIC4 NFKB1 CXCL2 IRAK2 CCL4 PNRC1 CCSER2 HCK HCAR3 IL6 SYNPO2 SOCS3 OASL SERPINB8 PLK3 DNAJA1 FOXN2 CD83 PI4K2B TNFRSF9 TNFRSF10B ACSL1 PELI1 RIN2 PIK3AP1 AZIN1 SAV1 EHD1 NAB1 KCNA3 SOD2 TAGAP ADORA2A-AS1 CCL20 ICAM1 TNFAIP8 NBN TAB2 GIMAP5 RIPK2 NLRP3 TRAF1 RND1 MAP3K4 HNRNPC NFKBIA MCOLN2 SAMSN1 LDLR PMAIP1 FNBP1 PIM3 FJX1 CLEC4E DCUN1D3	down	***
GSE22886_NAIVE_CD8_TCELL_VS_DC_DN	0.0000000	0.0000000	1.0376962	-0.4867302	-2.588158	185	RAB11FIP1 SLC31A2 PNPLA6 STAC HHEX MNDA CAT RAPGEF2 RCOR1 EGR2 LMO2 CORO1C FLVCR2 HMGCR ARL8B SPG21 MAN2B1 ENTPD1 CLEC7A IFI30 ANXA5 ABHD6 LAMTOR3 TXN TUBB6 ATP6V1B2 CD58 CST3 ZMIZ1 FABP5 DUSP3 PPT1 DAB2 SLC7A8 CEBPA PLBD1 LY96 RIT1 VIM M6PR TM6SF1 CAPZA2 FCER1G GCA DSE HTT MPC1 HLA-DQA1 CRIM1 PI4K2A SNX3 VAMP3 CTSS PSEN1 PGD RAB31 ATP6V0B TBC1D12 SNX2 CD83 ZNF804A GRB2 SNX1 AP3B1 NDUFV2 PLCG2 SLC3A2 CD74 ATP6V1A GNG5 TMEM70 CCR1 NPTN CLASP2 RXRA TIAM1 SOAT1 DAPK1 GLUL GLRX2 CREG1 WDFY3 RNH1 FEZ2 CTSH FTL ATP1B1 PTGS1 CYP51A1 HLA-DRB1 MFSD1 GPR137B DLD RCBTB2 ZFYVE21	down	***
GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP	0.0000000	0.0000000	1.1421912	0.5754935	2.581565	173	HELLS KIF20A CDC45 PARPBP MCM10 BUB1B NEK2 POLQ PBK KIF18B NDC80 DEPDC1 BRCA1 TTK GINS1 RACGAP1 IQGAP3 GTSE1 ASPM STIL PLK1 NUF2 CDCA8 AURKB CENPA ESPL1 CDC6 TPX2 CCNB2 FIGNL1 RBBP8 UHRF1 MCM2 RAD54B MYBL2 PRC1 MUC20 SPDL1 MELK HMMR KIF23 CEP55 KNTC1 BUB1 AUNIP TOP2A AURKA KIF2C MCM7 CENPW RRM2 RAD54L KIF11 PASK CDC25C PSMG4 LIG1 MAD2L1 CKAP2L RAD51AP1 SPC24 DSCC1 PPIL1 KNSTRN CKS1B C12orf75 NUSAP1 ASF1B CDK1 CENPH BIRC5 C1orf112 GMNN NCAPG DNA2 NEIL3 FEN1 SPAG5 DIAPH3 CENPP UQCRFS1 ALDH7A1 KIF22 TK1 ESCO2 GINS2 SPAG1 FHL2 ATAD5 CDC20 CENPM CKAP2 MCM5 CD2BP2	up	***
GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN	0.0000000	0.0000000	1.0276699	-0.4839901	-2.568535	176	FCN1 IL1B MNDA PTP4A2 PID1 FYN LY86 CLEC10A P2RY13 NCF2 CD1C IL1RN AGTPBP1 IGSF6 PILRA FGR ANXA1 ATP2B1 ASAP1 CD33 LMNA ASAH1 ENTPD1 CLEC7A CSRP1 ITGA5 IFI30 PICALM ANXA5 SIRPA RGCC TMEM123 CST3 EPB41L2 ARRB1 CASP1 LIMS1 YBX3 KLF11 PLBD1 COTL1 ITGAX ID2 EVI2A HCK EMP3 PRCP RBPJ SGK1 SEC14L1 C2CD2 RAB31 KCTD12 RHOG CSTA PTGER4 PSTPIP2 GMFG SERPINB6 CST7 PPM1F ATG3 CD1D PDLIM1 CD86 APLP2 LGALS3 DOK2 MFNG IL18 SLC35D2 RTN1 SEMA4A CEBPD NLRP3 MEGF9 S100A4 ICAM3 CD1E LYST RNH1 CNN2 CACNA2D3 EGR1 CTSH CDKN1B AOAH TUBA1A ATP1B1 PTGS1	down	***
GSE10325_BCELL_VS_MYELOID_DN	0.0000000	0.0000000	1.0276699	-0.4869350	-2.566722	172	SLC31A2 SASH1 HMOX1 ASGR1 OSBPL1A FBP1 PTPRE COQ2 LMO2 CCDC88A FCER1A RTN3 AQP9 MYD88 C5AR1 CLEC10A P2RY13 NCF2 IL1RN SLC11A1 IGSF6 PILRA LILRB3 TNFRSF8 SH2B3 HBEGF SLC7A7 NAAA CLEC7A ANXA5 SIRPA CD93 SRGN TCF7L2 CYBRD1 CFD PTGIR KIAA0513 CASP1 KLF4 PLAUR CPVL DRAM1 CEBPA PLBD1 COTL1 KCNMB1 CD302 TM6SF1 DUSP1 HEXB OASL KCTD12 HK3 CSTA LGALS2 FOS TNFSF13 RIN2 GALC LGALS3 CCR1 FCGRT RGS2 RXRA ICAM1 CEBPD CDKN1C NLRP3 ALDH2 MEGF9 S100A4 DAPK1	down	***
GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN	0.0000000	0.0000000	1.0276699	-0.4803919	-2.554103	180	ACP5 SASH1 OSBPL1A MNDA CAT ADCY9 ENG HSD17B11 LMO2 BACH1 SLC15A3 P2RY13 TBC1D2 MKNK1 MANBA LAMP1 AGPAT4 SLC11A1 EPB41L3 FAM49A CD36 DPEP2 ARHGAP10 PLA2G7 MCTP1 CD33 ASAH1 RNASE1 ADIPOR1 STOM LAIR1 TFEC IL10 ARRB1 DUSP3 PPT1 ITM2B PXDC1 KLF11 DAB2 ATP6V1D LY96 RIT1 CDKN1A TM6SF1 PLEK GCA DSE IL7R TDRD7 HEXB HCK NINJ1 TMEM9B CYB5R1 SERPINB8 C2CD2 C1QA KCTD12 CTSZ ATP6V0B MOB1A TNFSF13 CD74 RIN2 BAZ2B CD86 LGALS3 SERINC3 CLEC2B BMP2K IL18 CALHM2 SEMA4A CEBPD MEGF9 METTL7A CTSC PTEN DNAJB9 MMD CREG1 EMC3 EHD4	down	***
GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP	0.0000000	0.0000000	1.0276699	0.5862499	2.550531	131	TICRR MCM10 TROAP BUB1B CENPF POLQ UBE2T KIF18B TTF2 PIF1 BRCA1 TTK CDCA2 RACGAP1 E2F8 GTSE1 KIF14 ANLN POLE ASPM PLK1 CDCA8 ECT2 CDC6 TPX2 UHRF1 RAD54B PRC1 XRCC2 CCNF NCAPD2 PODXL2 KIF23 STAG3 MKI67 KIF15 KNTC1 TOP2A AKAP1 KIF11 FANCD2 LIG1 SARS2 CKAP2L BRIP1 INCENP NCAPG2 ANAPC5 HDGF CENPJ RFWD3 GMNN DNA2 SEC61G NEIL3 EZH2 NUP205 SPAG5 TACC3 MNS1 AARSD1 KIF22 CHTF18 ESCO2	up	***
GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_UP	0.0000000	0.0000000	1.1239150	0.5678323	2.548666	177	TRIP13 LINC00342 FOXM1 CDC45 FANCI TROAP CHEK2 BUB1B NEK2 CCNB1 TIMELESS FAM153B CLGN NDC80 PRIM2 BRCA1 PHGDH TTK GINS1 GTSE1 SLC27A2 KIF14 GMPS POLE STIL CENPA ESPL1 CDC6 TPX2 CCNB2 RBBP8 UMPS COCH XRCC2 CCNF ZWINT MELK HMMR EXO1 NUDT1 KIF23 CHAF1A RPL39L HLTF KNTC1 BUB1 FANCA TOP2A AURKA NUP155 KIF2C RRM2 KIF11 GPSM2 CDC25C LIG1 CHEK1 RAD51AP1 PKMYT1 BLM SKP2 CKS1B EFCAB11 CDKN2C TMEM106C CDK1 POLE2 DNA2 NUP205 SPAG5 FGFR1OP RNASEH2A NRGN NET1 FANCG CCNE1 TUBG1 DLGAP5 ALDH7A1 KIF22 SLC37A4 TK1 DTYMK ANP32E KIF20B	up	***
GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP	0.0000000	0.0000000	0.9759947	-0.4859121	-2.546151	165	PHACTR1 TUBB1 SIK1 INSIG1 EGR2 OTUD1 BACH1 C5AR1 YPEL5 ARL8B STX11 PPM1D RBM7 SH2B3 B3GNT5 HBEGF TACC1 TM2D3 CHMP1B BTG2 NR4A1 TRAF6 NFE2L2 UBE2D3 TIPARP RHOB ZMIZ1 CSRNP1 CDADC1 MTMR6 ITPRIP ATP11A-AS1 COQ10B ZFAND5 CDKN1A CXCL2 ATF3 DUSP1 ARL4A SMNDC1 RASGEF1B SIAH1 USP25 ETF1 HCAR3 DCP1A GZF1 TMOD1 AREG SGK1 SOCS3 RAB8B UTRN ETV3 ARL5B JUNB PTGER4 MCM9 BAG5 CD83 GPR183 N4BP3 OSM FSD1L REL FOS PTP4A1 YTHDF3 FOSB CHORDC1 ABHD13 PDE12 CRY1 GNA13 RGS2 CLEC2B CCL20 NR2E3 RNF138 DCTN4 CXCR4 RIPK2 MEX3C CUL3 MAFK C20orf203 DNAJB9 SAMSN1 CNTNAP3B	down	***
GSE29618_PDC_VS_MDC_DN	0.0000000	0.0000000	1.0175448	-0.4785731	-2.539787	176	FCN1 MNDA PTP4A2 PID1 LY86 LMO2 CLEC10A P2RY13 STX11 BCL2A1 NCF2 CD1C IL1RN TRIB1 PILRA FGR ANXA1 ATP2B1 SPG21 ASAP1 CD33 LMNA ENTPD1 CLEC7A IFI30 PICALM ANXA5 STOM CD93 SPI1 CST3 TIPARP RHOB FBXL5 PTPN12 ARRB1 PPT1 CASP1 YBX3 KLF11 PLBD1 ITPK1 TMBIM1 COTL1 ITGAX PTPRC ID2 ARHGDIB HCK EMP3 RBPJ YBX1 SGK1 C2CD2 PHF10 RAB31 JUNB RHOG CSTA PTGER4 PSTPIP2 GMFG SERPINB6 LGALS2 NDST1 SLC25A24 ATG3 CD1D SERPINB1 PDLIM1 CD86 LGALS3 RTN1 CEBPD MEGF9 S100A4 ICAM3 CD1E IQGAP1 CREG1 RNH1 CNN2	down	***
GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN	0.0000000	0.0000000	1.0376962	-0.4791976	-2.538701	186	SASH1 ZC3H12C IL1B FABP4 NUP54 RAPGEF2 BMP2 EGR2 CCRL2 CAV1 CITED2 CDC42EP2 SLC15A3 STX11 BCL2A1 IL1RN IL23A IER2 CCNL1 HBEGF SBDS SDE2 BTG2 MAP3K8 KLF6 SLAIN2 NDEL1 SRGN MCL1 TIPARP IL10 CSRNP1 TLE4 RAB12 PLAUR COQ10B ID3 ZFAND5 KLF7 ATF3 C9orf72 ID2 CCL4 PNRC1 DUSP1 PLEK SPRYD7 MAFF USP16 RASGEF1B BTG1 RBM39 GPBP1 ETF1 SLC25A25 ETV3 ARL5B MTMR14 KCTD12 HSPA1B DUSP8 PTGER4 CD83 OSM MALT1 REL FOS CDK17 TREX1 EHD1 TGIF1 DUSP5 ZBTB11 GPR84 SOD2 GTF2B RNF2 ICAM1 ABL2 IER5 RIPK2 FBXO30 PTCH1 TRAF1 JMJD1C TNFSF9 NABP1 DNAJA2 RABGEF1 PIM3 HERPUD1 SERPINE1 ZNF800 CLEC4E OSGIN2 SLC38A2	down	***
GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP	0.0000000	0.0000000	0.9653278	-0.4834884	-2.533451	165	CD300LF HMOX1 CXCL16 PPARG MNDA CYP27A1 THBD OSCAR TMEM170B AATK LMO2 CORO1C ALAS1 NCF2 SLC11A1 EPB41L3 IGSF6 PILRA LILRB3 HBEGF LIFR ASAH1 GM2A IFI30 ANXA5 ANPEP SIRPA SLC25A37 GRN TFEC ARHGEF2 ATP6V1B2 UNC45B MSR1 MPEG1 PTAFR VRK2 TPP1 CLIC4 LY96 HPSE GCA DSE LIN7A HCK HCAR3 RAB31 CTSZ ATP6V0B GSTO1 PSTPIP2 LGALS2 ZBED5 NOP10 ALDH3B1 IRF5 TCF4 DOK3 FPR2 TSC22D1 CD86 GNB4 LGALS3 BRI3 FCGRT KYNU SLC8A1-AS1 SLC43A2 GLUL BCAT1 TMCC3 NRP2 DOCK4 CREG1 WDFY3 DMXL2 CSF2RB LHFPL2 AOAH FTL FPR1 WDR41 C6orf62 MFSD1 DAPP1	down	***
GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN	0.0000000	0.0000000	1.0073180	-0.4811146	-2.532493	170	SLC31A2 HMOX1 FCN1 MCOLN1 OSBPL1A MNDA CYP27A1 CAT LIPA FIG4 CCRL2 SAMHD1 CITED2 P2RY13 MARCO MANBA NCF2 SLC11A1 EPB41L3 PILRA FGR MAN2B1 SLC7A7 IFI30 ABCG1 KLF6 STOM LAIR1 RB1 SPRY2 EVI2B GPA33 CPVL RUNX1T1 DAB2 DRAM1 THBS1 LY96 ERP44 CDKN1A ITGAX SELL CCL4 CD302 FCER1G FKBP15 GLB1 HCK KANK1 VAMP3 PGD C1QA KCTD12 LTBP2 PSTPIP2 FOS EPPK1 RIN2 SORT1 GSAP CD1D APLP2 CCR1 FCGRT KYNU CLEC2B RXRA OPN3 MS4A4A GIMAP5 SLC2A9 THEMIS2 LPAR6 RNH1 MAN1C1 TMEM50A CLEC4E AOAH S100A8 KBTBD11	down	***
GSE29618_BCELL_VS_MDC_DN	0.0000000	0.0000000	0.9969862	-0.4773364	-2.531166	181	RAB11FIP1 CD101 FBP1 CAT DPYSL2 LMO2 CCDC88A FCER1A ST3GAL6 CLEC10A PRKAR1A CD1C TRIB1 EIF4A1 ASAP1 CD33 LMNA IFI30 PICALM ANXA5 LCP1 STOM IL18R1 CD93 GRN TXN CST3 TIPARP ARRB1 DUSP3 CASP1 KLF4 DAB2 TPP1 PLBD1 ITPK1 COTL1 ITGAX VIM AXL ID2 CAPZA2 CPT1A GNAQ GNAI2 CALM2 PRCP RBPJ RAB31 KCTD12 RHOG RCAN1 GSTO1 GLIPR1 PSTPIP2 GMFG CAP1 GRSF1 ATG3 MYL12A PEA15 CD1D GNG5 TOB1 ETS2 SELPLG IL18 ARPC2 FKBP1A WDR1 RTN1 SEMA4A RTN4 CEBPD ACTB S100A4 CD1E ARPC5	down	***
GSE34156_TLR1_TLR2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP	0.0000000	0.0000000	0.9653278	-0.4816921	-2.525293	163	CXCL3 CD300LF HMOX1 CXCL16 PPARG CYP27A1 PTPRE OSCAR LMO2 CCDC88A CORO1C NCF2 SLC11A1 EPB41L3 IGSF6 PILRA LILRB3 ASAH1 GM2A IFI30 ANXA5 ANPEP SIRPA SLC25A37 CD93 GRN TFEC ATP6V1B2 MSR1 DUSP3 MEFV MPEG1 LIMS1 PTAFR VRK2 CLIC4 CTSD KCNMB1 HPSE TLR4 DSE GPR157 ACTR2 HCK LACC1 HCAR3 KLRB1 HPGDS RAB31 CTSZ TYROBP IFNGR1 PSTPIP2 PRKCE ATP13A3 LGALS2 CD151 RIN2 IRF5 CHIA DOK3 FPR2 CD86 GNB4 LGALS3 BRI3 CCR1 FCGRT KYNU PLEKHO2 PITPNA RAB5A ACTB GLUL BCAT1 TMCC3 NRP2 DOCK4 NABP1 CREG1 WDFY3 RAB2A DMXL2 CSF2RB DUSP6 CLEC4E LHFPL2 FTL	down	***
GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	0.0000000	0.0000000	0.9969862	-0.4794697	-2.523834	170	ACP5 CD52 HVCN1 DPYSL2 FIG4 FYN CCDC88A MANBA CD9 IL23A TXNIP CD36 DPEP2 CORO6 GM2A CSGALNACT2 TTYH2 RNASE1 LAIR1 C1orf162 RGCC NFE2L2 SORBS3 EVI2B CYBRD1 AHNAK SDCBP RRM2B ID3 TPP1 PLBD1 TMBIM1 PDE3B LBH EVI2A CRIM1 HGSNAT NCKAP1L PRCP PDK4 SLC8A1 ELF1 CTSS RAB8B UTRN AQP3 MITF STAT4 GSTO1 GCNT4 SNRK PELI1 TIMP2 LGALS3 TOB1 DECR1 PRDM8 CALHM2 RTN1 ARRB2 ACAP2 NLRP3 METTL7A CD3G CREG1 LYZ ARRDC2 SPPL2A SH3BGRL3 CLEC4E C5 ZYX RAB37 CD109 NFAM1 PDE7B RCSD1 RCBTB2 PPFIBP1 UEVLD LRP1 CD4 FAM111A ANKRD44 GSN	down	***
GSE22886_NAIVE_TCELL_VS_DC_DN	0.0000000	0.0000000	0.9865463	-0.4712515	-2.520419	183	EPAS1 SLC31A2 KMO STAC PTPRE LIPA RCOR1 CCDC88A CORO1C FLVCR2 EPB41L3 IGSF6 CD36 PLA2G7 SPG21 MAN2B1 ASAP1 ADAM17 ENTPD1 ANPEP ABHD6 SIRPA NFE2L2 ZMIZ1 PPT1 SDCBP DAB2 GAA SLC7A8 CEBPA PLBD1 LY96 ATG7 RIT1 VIM M6PR PLEKHB2 GCA DSE SLC6A6 TM9SF2 DEGS1 CRIM1 PI4K2A GLB1 HGSNAT SNX3 VAMP3 BCAR3 PGD SLCO2B1 C1QA MTMR14 MITF KCTD12 CTSZ ATP6V0B IFNGR1 TBC1D12 ZNF804A SNX1 AP3B1 NDUFV2 PEA15 KYNU ZNF267 VASH1 LRP12 CYB5R4 ALDH2 DAPK1 STAM2 GLRX2 ARPC5 DOCK4 CREG1 WDFY3 EHD4 RNH1 FEZ2 ZFYVE26 LHFPL2 TREM2 FTL ATP1B1 PTGS1 CYP51A1 MFSD1 GPR137B MPV17	down	***
GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP	0.0000000	0.0000000	1.0864405	0.5589115	2.510807	171	TRIP13 HJURP CDC45 FANCI ELOVL6 CCNB1 CENPF PTPRN2 GINS1 SNF8 CDCA8 AURKB CENPA PTTG1 TPX2 CCNB2 RBBP8 MCM4 MCM2 TYMS MYBL2 PRC1 DTL SHMT2 ZWINT CDT1 AGK MELK EXO1 CEP55 RPL39L EMC9 KIF15 KNTC1 BUB1 AURKA KLHL25 KIF2C MCM7 RRM2 WDHD1 KIF11 LMNB1 LIG1 PDZK1IP1 MRPS11 PTGDR2 BLM IDH2 PSRC1 CKS1B NCAPG2 PPIL2 NUSAP1 TMEM106C CBX5 BIRC5 C1orf112 GMNN FEN1 EZH2 SPAG5 MRPS12 RALGPS1 RNASEH2A FANCG UBFD1 DPP3 DLGAP5 KIF22 MRPL11 ZNF544 TK1 PKP4 IGHM CCDC51 NTN3 COG4 COX10 CDC7 CDC20 CENPM PPCDC LANCL2 RCC1 ATAD2 CCNA2 RAD51 TPGS2 ZWILCH WDR76 UQCRQ CENPE GGCX CDC25B UBE2C ZMYND10 RAD1	up	***
GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN	0.0000000	0.0000000	0.9214260	-0.4785608	-2.503444	158	CXCL3 ACVRL1 CXCL16 SGK3 PPARG AATK LMO2 CORO1C NCF2 EPB41L3 IGSF6 PILRA LILRB3 ASAH1 GM2A EMILIN2 IFI30 ANXA5 ANPEP ZNF697 SIRPA SLC25A37 CD93 GRN TFEC ATP6V1B2 PTPN12 MSR1 CYBRD1 MPEG1 LIMS1 PTAFR CLIC4 CTSD HPSE DSE GPR157 HCK LACC1 HCAR3 KLRB1 KIF13A PGD FOXP1-IT1 SLC35E4 RAB31 CTSZ TYROBP PSTPIP2 ATP13A3 LGALS2 ACSL1 CD151 RIN2 IRF5 DOK3 FPR2 CD86 EWSR1 GNB4 LGALS3 BRI3 CCR1 KYNU PLEKHO2 SLC8A1-AS1 PITPNA SLC43A2 ACTB HAVCR2 GLUL BCAT1 SIGLEC9 TMCC3 NRP2 CREG1 ANO6 DMXL2 CSF2RB AQP5 LHFPL2 FTL	down	***
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN	0.0000000	0.0000000	1.0768682	0.5573423	2.501456	174	FOXM1 KIF20A CDC45 MCM10 BDH1 FANCI ELOVL6 BUB1B CCNB1 POLQ APOLD1 GBAP1 PBK TTF2 TTK HILPDA TRAIP ASPM STIL CDCA8 CENPA PTTG1 ESPL1 CDC6 CCNB2 RBBP8 MCM2 TYMS CDC25A UMPS DTL MIS18A ZWINT MYL6B NME1 HMMR CISD1 CEP55 MKI67 KIF15 KIF3B BUB1 LGMN TOP2A AURKA POLA2 KIF2C MCM7 RRM2 RAD54L KIF11 AIMP2 CHEK1 RAD51AP1 DCTPP1 TST CKS1B NUSAP1 TMEM106C POLE2 BIRC5 GMNN NCAPG NEIL3 FEN1 SPAG5 POLR2H UBFD1 DPP3 TUBG1 DLGAP5 FAH LMNB2 RAD51D TK1 DTYMK MLEC GINS2 CCDC51 SAP30 PFAS CKAP5 CDC20 CENPM ZNF248 PPCDC MCM5	up	***
GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN	0.0000000	0.0000000	0.9436322	-0.4720198	-2.484292	169	SLC31A2 CD300LF SWAP70 CXCL16 MNDA CYP27A1 PTPRE TMEM170B LMO2 CORO1C ALAS1 NCF2 SLC11A1 EPB41L3 MOB1B IGSF6 PILRA LILRB3 ASAH1 GM2A EMILIN2 IFI30 ANXA5 ANPEP ZNF697 SIRPA SLC25A37 GRN TFEC ARHGEF2 ATP6V1B2 UNC45B RAB12 MPEG1 MED11 PTAFR TPP1 CLIC4 LY96 HPSE CAPZA2 GCA DSE GPR157 LIN7A HCK CD8B PGD RAB31 KCTD12 VPS26A TMEM251 PSTPIP2 LGALS2 ZBED5 NOP10 ALDH3B1 IRF5 TIMP2 TCF4 DOK3 FPR2 TSC22D1 CD86 GNB4 LGALS3 BRI3 KYNU SLC8A1-AS1 PITPNA GLUL BCAT1 SIGLEC9 NRP2 DOCK4 CREG1 WDFY3 DMXL2 CSF2RB LHFPL2 AOAH FTL	down	***
GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP	0.0000000	0.0000000	0.9325952	-0.4712371	-2.472576	161	CXCL3 IL1A USP12 PPARG ADTRP IL1B DCSTAMP P2RY1 RAPGEF2 INSIG1 CCRL2 ST3GAL6 NEDD4L FOSL1 AQP9 TBC1D7 SFR1 OTUD4 IL23A STARD4 ATP2B1 SGMS2 HECW2 PPP1R15B TNIP3 MAP3K8 RGCC ADRB2 SPRY2 TXN IL10 CSRNP1 MOAP1 ACSL3 PLAUR TNFSF15 SPAG9 RIT1 CXCL2 ID2 TAF9 DUSP1 PLEK INHBA TP53BP2 RASGEF1B MMP19 RYBP SYNPO2 NSMAF JUN ARL5B PLK3 TMEM251 FERMT2 CCR7 HOMER1 GPRC5A DENND4A SNX9 SLC3A2 PTP4A1 NIPAL4 SAV1 TEX14 DUSP5 ADORA2A-AS1 ETS2 CCL20 GEM LDLRAD4 IL18 ABL2 MIR155HG FBXO30 NLRP3	down	***
GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN	0.0000000	0.0000000	0.9436322	-0.4710830	-2.469721	171	SLPI SLC31A2 ABHD5 FCN1 DENND5A MNDA MIR22HG PPP4R1 RTN3 AQP9 C5AR1 P2RY13 BCL2A1 NCF2 FRAT1 IGSF6 TRIB1 PILRA LILRB3 CLEC7A LITAF HLX NDEL1 SRGN TXN MCL1 ATP6V1B2 CD58 CFD PPT1 KIAA0513 BST1 VASP STX3 PLBD1 LY96 FAM49B ITPK1 TMBIM1 CTBS ID2 CD302 ARAP3 FCER1G PLEK EVI2A GCA PPP2R5A NRBF2 ANXA3 HCK NINJ1 S1PR4 HCAR3 SEC14L1 RAB31 TYROBP TREM1 CSTA SPATA2L RASSF2 RALB ACSL1 NOP10 BIN2 MME	down	***
GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP	0.0000000	0.0000000	1.0276699	0.5505188	2.466922	167	HELLS CDC45 BUB1B CENPF PBK NDC80 DEPDC1 BRCA1 TTK GINS1 RACGAP1 E2F8 KIF14 POLE ASPM PLK1 NUF2 CDCA8 AURKB ECT2 CDC6 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 PRC1 NCAPD2 HMMR KIF23 CEP55 MKI67 KIF15 BUB1 AUNIP TOP2A AURKA EME1 MCM7 CENPW CLSPN RRM2 WDHD1 RAD54L KIF11 MCM3 CHAF1B LMNB1 CDC25C LIG1 TOPBP1 CHEK1 ORC6 MAD2L1 RAD51AP1 SPC24 MRPS11 BRIP1 TADA2A INCENP CKS1B CBX5 ASF1B ANAPC5 CDK1 CENPH BIRC5 NCAPG DNA2 NEIL3 SPAG5 CENPP CCNE1 DLGAP5 TACC3 TK1 ESCO2 ANP32E FHL2 ATAD5 CKAP2 MCM5 CORO2A APOBEC2 CCNA2 PRIM1 PRR11 HDLBP SHCBP1 RAD51 ARHGAP11A WDR76 CPOX SMC2 CENPE ZBTB32	up	***
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN	0.0000000	0.0000000	1.0574636	0.5482754	2.462449	175	TRIP13 KIF20A HJURP KCNK5 CDC45 MCM10 CCNB1 GBAP1 KIF18B SORD BRCA1 RACGAP1 HILPDA ASPM CDCA8 AURKB CENPA ESPL1 TPX2 CCNB2 RBBP8 MCM4 MCM2 TYMS UMPS DTL ACY1 LIG3 SRPK1 MYL6B UQCC1 NME1 HMMR CISD1 KIF23 CEP55 CHAF1A MKI67 TP53BP1 FANCA LGMN TOP2A PUS7 VANGL1 POLA2 KIF2C MCM7 RRM2 RAD54L KIF11 CDC25C AIMP2 LIG1 DCTPP1 BLM CKS1B NCAPG2 NUSAP1 TMEM106C POLE2 UCK2 BIRC5 NCAPG FEN1 SPAG5 FANCG CCNE1 TUBG1 FAH LMNB2 RAD51D TK1 DTYMK GINS2 CCDC51 ZNF282 PFAS TIMM13 CKAP5 CDC20 PALB2 CENPM PPCDC MCM5 SRSF1 GINS3 IL12RB2	up	***
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN	0.0000000	0.0000000	1.0476265	0.5478664	2.462131	176	TRIP13 FOXM1 KIF20A HJURP MCM10 BDH1 FANCI BUB1B CCNB1 CENPF TIMELESS TUBB2B CDK4 RACGAP1 ASPM AURKB CENPA ESPL1 CDC6 TPX2 CCNB2 RBBP8 MCM4 MCM2 TYMS DTL MIS18A ZWINT MYL6B NME1 MELK HMMR NUDT1 KIF23 CEP55 MKI67 EMC9 MRPL15 TP53BP1 PCCB TOP2A AURKA APOL1 NDUFS2 SMARCAL1 MCM7 RRM2 KIF11 GNPDA1 BLM COMMD4 CKS1B NCAPG2 NUSAP1 TMEM106C POLE2 UCK2 CCT3 GOT2 UNG NCAPG PSMB5 FEN1 SPAG5 FADD FOCAD RNASEH2A SNRNP25 FANCG CCNE1 DPP3 TUBG1 DLGAP5 FAH MRPL11 RAD51D TK1 GINS2 TRIM32 CCDC51 PSMD2 LIMA1 CKAP5 CDC20 CENPM FAM50B MCM5 SRSF1 HAUS4 CCNA2 RAD51 ZWILCH GBP2 PGAM1 SNUPN SMC2 MTHFD1 PAICS UBE2C TUBA1C LXN NUP93	up	***
GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP	0.0000000	0.0000000	0.9653278	-0.4656427	-2.459707	174	MCOLN1 PPARG MIR22HG LPL GFOD1 SEC22C CORO1C GPCPD1 TBC1D7 ZCCHC2 TBC1D2 TSHZ1 TRIB1 GGA2 AVPI1 TXNIP CNST FBXO7 RRAGC LINC01010 IFI30 ABCG1 ZBTB21 SPRY2 CRTAM TMEM38B CD37 ATP6V1B2 RHOB FBXL5 MOAP1 ACSL3 ID3 DAB2 TNFSF15 MAP1LC3B STX3 TMBIM1 ITGAX ATF3 ZBTB43 UBASH3B FKBP15 AFF1 NRBF2 PI4K2A MMP19 HEXB CLN8 NRROS BCAR3 SGK1 SH3BP5 HIC1 TMEM251 KBTBD8 KLF2 RNASEK CD164 AKIRIN2 TGIF1 COL15A1 LGALS3 DOK2 TMEM70 BRI3 CCR1 PLEKHO2 AMD1 SERTAD1	down	***
GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP	0.0000000	0.0000000	1.0376962	0.5429162	2.438379	175	TRIP13 KIF20A EYA1 HJURP CDC45 TICRR PARPBP MCM10 BDH1 BUB1B NEK2 CENPF MPP6 MND1 KIF18B NDC80 PIF1 BRCA1 TTK GINS1 E2F8 POLE ASPM STIL NUF2 AURKB CENPA ESPL1 CDC6 CCNB2 FIGNL1 UHRF1 XRCC2 CCNF NCAPD2 WDR90 MELK EXO1 KIF23 CEP55 PAQR4 BUB1 TOP2A EME1 CLSPN RRM2 TTLL12 CDCA5 AKAP1 RAD54L MCM3 LIG1 CKAP2L SPC24 DSCC1 PKMYT1 BRIP1 FNTB CKS1B NCAPG2 C12orf75 NUSAP1 ASF1B BIRC5 GMNN PSAT1 NEIL3 EZH2 SPAG5 CENPP SPEF1 DLGAP5 SNRPA MNS1 GALNS KIF22 TK1 ESCO2 PKP4 KIF20B	up	***
GSE3982_NEUTROPHIL_VS_NKCELL_UP	0.0000000	0.0000000	0.9325952	-0.4649877	-2.437766	171	SLPI SLC31A2 SLC12A6 DENND5A TBX3 MIR22HG LYL1 AATK PPP4R1 BACH1 FOSL1 CDC42EP2 C5AR1 MSRA NEDD9 CD9 IL1RN ANPEP PCDH12 HLX ADIPOR1 LHX6 SPI1 UBE2D3 ATP6V1B2 FBXL5 AGO4 CFD SDCBP UHRF1BP1L DENND3 KLF7 SNIP1 ERP44 CD302 IGFBP2 ACTR3 TM6SF1 B9D2 ARL4A PINK1 SLC6A6 GNAQ TM9SF2 ANXA3 NCOA1 FOXN3 BTG1 SGK1 RNF141 PPP6C SEC14L1 ATP11A REL CAP1 RNF24 OGFRL1 ACSL1 PELI1 KLF2 PNPLA3 FPR2 GNG5 CCR1 ADAM10 SERINC3 XKR8 IQSEC1 TAB2 NLRP3 ICAM3 ARPC5 DNAJB9 CNTNAP3B DAZAP2	down	***
GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP	0.0000000	0.0000000	0.9436322	-0.4664024	-2.433567	168	RAB11FIP1 CD52 HMOX1 FCN1 PECAM1 MNDA LTA4H FBP1 GPR65 LRRFIP1 HSD17B11 LY86 INPP5K MYD88 C5AR1 YPEL5 TMX4 DPEP2 TACC1 ASAH1 NR4A1 CD37 CST3 EVI2B PPT1 SCP2 KIAA0513 BST1 KLF4 ZCCHC24 ITM2B PLBD1 CTSD LAPTM5 COTL1 CD302 EVI2A CARS2 MPC1 MAPRE2 ARHGDIB PRCP TECR CTSS IFNGR1 RASSF2 PPM1F CELF2 FOS KLF2 TIMP2 RPL21 CD86 FCGRT RGS2 TSPO JUND EIF3F SELPLG CCDC69 ARRB2 MS4A4A ALDH2 SCPEP1 RPS13 S100A4 ICAM3 THEMIS2 EID1 CNN2 LYZ PHYH CHP1 CRTAP NR4A2 CRBN EIF3L ZFP36	down	***
GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP	0.0000000	0.0000000	0.9436322	-0.4620404	-2.432090	170	SLC31A2 PPARG CD55 FBP1 RAPGEF2 MIR22HG PTPRE CLDND1 CD44 CCRL2 BACH1 AQP9 PAFAH1B2 NR3C1 IL1RL1 BCL2A1 CD1C ATP2B1 EIF1 EIF5 KLF10 KLF6 CLK1 UBE2D3 TXN MCL1 MOAP1 BNIP2 ADO MAP1LC3B TMED5 CDKN1A PAPSS1 CCND2 ZBTB43 CD53 RNF139 VAMP5 RUFY3 MAFF BTG1 SERTAD2 RBPJ ELF1 JUN SHOC2 RPL9 IFRD1 HSPA13 RGS13 RALB SNRK RRN3 ICAM2 ING3 TGIF1 HECW1 CTNNAL1 MEIS3P1 HBP1 GNG5 MAGOH GATA6 ZNF267 ETS2 GEM BNIP3L ABL2 ARPC2	down	***
GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN	0.0000000	0.0000000	0.8753251	-0.4728631	-2.428419	141	SEMA6B FCN1 MIR22HG FLVCR2 SLC15A3 IL1RN SLC11A1 CD36 EIF1 CLEC7A EMILIN2 IFI30 KLF10 ANPEP ADIPOR1 SIRPA CD93 GRN TFEC SRGN SPI1 CYBRD1 DUSP3 PPT1 SDCBP BST1 PLAUR ZFAND5 PLBD1 CTSD CDKN1A P2RY2 VIM HPSE PLEK DSE NINJ1 VAMP3 PGD SOCS3 IFNGR1 PPP1R15A ACSL1 SORT1 FXYD6 TIMP2 SERPINB1 APLP2 SOD2 LGALS3 CTIF RXRA ICAM1 BNIP3L CDC42EP3 SREBF2 GLUL DAZAP2 NRG1 CREG1 LYZ EGR1 ZYX S100A8 FPR1	down	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP	0.0000000	0.0000000	0.9436322	-0.4577897	-2.427516	181	SMAD6 CD52 SASH1 SWAP70 DENND5A TAL1 HHEX GATA2 PTPRE RAMP2 ARRDC4 FYN CD44 LY86 LMO2 SAMHD1 MYADM AQP9 MEF2A TGFBR2 TLCD2 ANXA1 MAN2B1 UBL3 CD33 ADAM17 PCYOX1 ENTPD1 ZNF503 LITAF PPP3CA SIRPA IL18R1 TFEC ARRB1 AHNAK ST3GAL2 TJP1 SOCS5 ITIH5 ITGAX C9orf72 PTGER3 SMAD7 PLEK KLRD1 ANXA3 TDRD7 HCK PROCR PRCP RNF149 RGS18 MITF RAB31 KCTD12 TYROBP GLIPR1 CD7 OGFRL1 CD34 MOB1A RHOQ RRAS IRF5 ZNF521 VAV3 ITGA9 TSC22D1 CD86 CD81 PLA2G15 GEM IL18RAP IER5 S100A4 SAMSN1 RORA THEMIS2 HEBP1 EID1 FCRL1	down	***
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN	0.0000000	0.0000000	0.8986712	-0.4661357	-2.426814	156	DPYSL2 ST6GALNAC3 SIK1 RGS9 DDX6 CITED2 IL1RL1 AGPAT4 ZEB2 STARD4 ATP2B1 BTG2 SERINC1 FZD4 KLF6 GATA3 NR4A1 RGCC IL18R1 ATP10A RHOB IL10 AHNAK ZFAND5 OSTF1 ATF3 HOPX ARC DUSP1 TBC1D4 HGSNAT SLC25A3 ELF1 NEK7 SLC35E4 STAT4 CUL4A ETS1 GLUD1 PLK3 JUNB EEA1 GPR183 PTGER2 GRASP COBLL1 GPRIN3 MBP FOSB JMJD6 DCK KCTD10 PIM1 TAGAP THAP11 RGS2 SPOCK2 SYT11 HSPA2 IL18RAP RAB5A HSP90AA1 ULK2 ADORA2A KLRK1 FDFT1 RORA NABP1 IQGAP1 ZFAND2A TOX2 ATF4 ENDOD1 HIPK1 ITGB1 ARL4D TUBA1A CD69 DNAJB1 ATP2B4 PLCB4 SIRT1 EBI3 MYO1F EMP1 PNP FAM107B	down	***
GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN	0.0000000	0.0000000	0.9436322	-0.4561408	-2.425500	185	ARHGAP31 IL1A CXCL16 HVCN1 SOWAHC ZC3H12C GPR65 RAPGEF2 CCRL2 BCL2A1 IL1RN IGSF6 FGR IER2 SEMA6D RBM7 ADAM17 ITGA5 BTG2 MAP3K8 HDC SERPINB9 NR4A1 NFE2L2 MCL1 PTPN12 CSRNP1 STAT5A PTGIR CCL22 FOXO1 PTPRO REST VASP CDKN1A CXCL2 PNRC1 DUSP1 N4BP1 PIK3R5 KPNA3 MAFF HCK AREG IL6 DDHD1 EBAG9 SOCS3 JUNB PTGER4 SKIL IFRD1 GLIPR1 CD83 SMU1 PSTPIP2 OSM GRASP RBM22 FAM177A1 ACSL1 UBXN2A EHD1 GSAP TGIF1 DUSP5 NAB1 IFNAR1 CD86 PIM1 GPR84 SOD2 TAGAP PLEKHO2 ETS2 ICAM1 SPIB NLRP3 TRAF1 MCOLN2 TNFSF9 SAMSN1 SPATA13 HERPUD1 CSF2RB NR4A2 CX3CR1	down	***
GSE14415_NATURAL_TREG_VS_TCONV_DN	0.0000000	0.0000000	0.9969862	0.5406398	2.411397	162	PRLR HELLS CDC45 BUB1B TRNP1 CENPF IGF2BP3 PBK NDC80 BRCA1 TTK GINS1 AGFG2 IQGAP3 E2F8 KIF14 ASPM PLK1 NUF2 CDCA8 TPX2 CCNB2 UHRF1 MCM4 MCM2 PRC1 NCAPD2 HMMR KIF23 CEP55 KIF15 BUB1 AUNIP TOP2A AURKA MCM7 CLSPN RRM2 WDHD1 RAD54L KIF11 MCM3 CHAF1B LMNB1 CDC25C LIG1 TOPBP1 CHEK1 MAD2L1 CKAP2L SPC24 BRIP1 BLM NRTN CKS1B CBX5 ASF1B CDK1 CENPH BIRC5 XRRA1 NCAPG NEIL3 SPAG5 CENPP DLGAP5 TACC3 OSBPL3 TK1 CHTF18 ESCO2	up	***
GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000000	0.0000000	0.9101197	-0.4598981	-2.411083	171	KRT81 SWAP70 ABHD5 PECAM1 HHEX GPR65 PTPRE AATK LMO2 PPP4R1 BACH1 RHOA ANXA1 DPEP2 SH2B3 CD33 SERINC1 LUZP1 HDC CAV2 ZFYVE16 BAG1 FLI1 ZMIZ1 PTPN12 EVI2B TLE4 BST1 FAM124B CDIP1 DRAM1 MAP1LC3B TM6SF1 CLK4 TAF9 PPP2R5A TM9SF2 LMBRD1 FRY AREG BCAR3 PSEN1 CRNKL1 SF3B1 DHX15 STX7 PSTPIP2 YWHAZ RALB NDUFV2 PLCG2 RHOQ PELI1 PTP4A1 AZI2 NOP10 CHPT1 VAV3 MILR1 SERPINB1 BAZ2B GALC HBP1 PLAA OPN3 CYB5R4 ESYT1 ALDH2 OSER1 CD19 MARC1 KIT DAZAP2 CREG1 LYZ HTRA2 CHP1 SVIL ZNF106 OSGIN2 TREM2 SH3GLB1 RB1CC1 KBTBD11	down	***
GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP	0.0000000	0.0000000	1.0175448	0.5332642	2.408828	185	TRIP13 HELLS KIF20A HJURP CDC45 FANCI CCNB1 CENPF TIMELESS POLQ NDC80 PHGDH RACGAP1 SLC27A2 GMPS PMS2P5 ASPM STIL PLK1 CDCA8 CENPA PTTG1 ESPL1 TPX2 CCNB2 GOLGB1 RBBP8 MCM4 MCM2 PRC1 DTL SRPK1 ZWINT CDT1 MELK HMMR NUDT1 CEP55 KIF15 KNTC1 AURKA POLA2 KIF2C MCM7 MPHOSPH9 RRM2 RAD54L KIF11 CDC25C MCCC2 SLC9A3R1 MAD2L1 RAD51AP1 BLM IDH2 NUSAP1 CDK1 GMNN NCAPG NEIL3 FEN1 FGFR1OP IFT52 FANCG CCNE1 VIPAS39 DLGAP5 TACC3 LMNB2 KIF22 MRPL11 TK1 DTYMK GINS2 RNF187 CKAP5 CDC20 CENPM FAF1 CDR2 MCM6 TDP1 SNRPD1 GINS3 CREB3L2 STK39 CCNA2 PRIM1 DCPS TTC31 RAD51 TPGS2 GRAMD1B	up	***
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN	0.0000000	0.0000000	1.0175448	0.5361621	2.406517	177	TRIP13 KIF20A HJURP MCM10 BDH1 FANCI BUB1B CCNB1 CENPF CDK4 RACGAP1 HILPDA ASPM AURKB CENPA ESPL1 CDC6 TPX2 GAPDH CCNB2 MCM4 MCM2 TYMS CDC25A DTL SRPK1 ZWINT MYL6B SPDL1 NME1 RANBP1 MELK HMMR NUDT1 CEP55 EMC9 KIF15 MRPL15 TP53BP1 TOP2A AURKA KIF2C MCM7 RRM2 KIF11 AIMP2 CHEK1 RAD51AP1 DCTPP1 TBC1D8 BLM PHB CKS1B NCAPG2 TMEM106C POLE2 UCK2 CCT3 GOT2 POLR3K UNG NCAPG TRAP1 PSMB5 FEN1 SPAG5 LRRC42 RNASEH2A POLR2H FANCG DPP3 TUBG1 DLGAP5 FAH LMNB2 MRPL11 TK1 MSRB2 GINS2	up	***
GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	0.9325952	-0.4532655	-2.403526	181	SLC31A2 PNPLA6 KLF13 MNDA PTPRE RTN3 C5AR1 TBC1D2 NCF2 SLC11A1 LILRB3 ANXA1 SLC7A7 ASAH1 CLEC7A IFI30 PICALM KLF10 CD93 GRN SRGN TCF7L2 RAB14 ZMIZ1 DUSP3 PPT1 SDCBP CASP1 VASP TPP1 PLBD1 LY96 CTSD VIM ID2 FCER1G EVI2A GCA HEXB HCK VAMP3 SGK1 PGD MTMR14 RAB31 KCTD12 TYROBP RHOG IFNGR1 CSTA SERPINB6 RPS6KA1 TNFRSF10B TNFSF13 ATG3 RIN2 TIMP2 ATP6V1A ATP6V0C ATXN1 LGALS3 RXRA ARRB2 SEMA4A RTN4 CDC42EP3 S100A4 GLRX2 SNAP29 THEMIS2 CREG1 RNH1 FEZ2 LYZ CSF2RB TMEM50A DUSP6 SVIL HIPK1 ITGAL FTL S100A8	down	***
GSE45365_WT_VS_IFNAR_KO_BCELL_DN	0.0000000	0.0000000	0.9436322	0.5393145	2.386474	151	SLC16A14 FOXM1 KIF20A ADH1C PCDHGA10 PARPBP C1QTNF6 TROAP CENPF POLQ UBE2T KIF18B SLC2A1 NDC80 DEPDC1 DEPDC1B TTK CDCA2 KIF14 FOXE1 ANLN NIPSNAP1 NUF2 AURKB CENPA PTTG1 ESPL1 CCNB2 BCL2L14 IGFBPL1 ALDOC KIF27 ZNF608 COQ3 CEP55 MKI67 EMC9 CYP24A1 BUB1 TOP2A CDCA5 TMEM45A WDHD1 PCDHGB7 KIF11 CKAP2L RAD51AP1 SPC24 DPY19L1P1 SLITRK6 SLC28A2 TST THPO FLNB FGGY NUSAP1 ASF1B DNER BIRC5 ENPP3 NEIL3 FEN1 SPAG5 SLC35F3 DIAPH3 CASC1 FGFR1OP	up	***
GSE16266_CTRL_VS_LPS_STIM_MEF_UP	0.0000000	0.0000000	0.9101197	-0.4488858	-2.384781	179	SMAD6 LPIN2 HMOX1 SWAP70 OLR1 DLC1 TMEM52B ENG COQ2 BMPR2 INPP5A MEF2A IER2 ZBTB4 SLC7A7 ITGA5 KLF10 CD58 ZMIZ1 MOAP1 LIMS1 SLC46A2 ZSWIM6 REST ID3 THBS1 CEBPA DENND3 FMNL3 SSH1 KCNMB1 ID2 ARAP3 DUSP1 ELK3 SMAD7 GPR157 RASGEF1B BTG1 SPIN1 RYBP SLCO2B1 NOTCH1 DESI2 PLK3 JUNB DNASE2 SKIL IDS MORC3 GPRIN3 CDK17 RUNX3 TFEB ZRANB1 TGIF1 KCTD10 MAP3K2 GNB4 STK40 GNA13 PLEKHO2 SLC43A2 VASH1 MIR155HG SERTAD1 CEP170 ITPRIPL2 CALHM2 BLOC1S2 CXCR4 HAVCR2 PSME4 ISCU NFKBIA SIGLEC9 SKI TMCC3 GRB10 TRIM36	down	***
GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP	0.0000000	0.0000000	0.9101197	-0.4499220	-2.383469	175	SLC31A2 USP12 ZC3H12C CLDND1 TMOD3 CORO1C GPCPD1 CDC42 WBP4 SNHG5 EIF4A1 CHMP1B EIF1 SDE2 AHRR CSGALNACT2 ZBTB21 PTX3 BFAR RGCC NFE2L2 NDEL1 BTG3 PPP3CC ZMIZ1 PLAUR MAP1LC3B SEC24B PER2 LRRC40 ATF3 ID2 CCL4 MAFF RSRC2 ZDHHC20 CLN8 SERTAD2 MCMBP PPIL4 CREBRF SGK1 NEK7 ETV3 JUN ARL5B PTGER4 REL TAGLN2 GAS2L3 AGFG1 RRN3 CDK17 PPTC7 MAPK8 SAV1 EHD1 ZBTB1 ZFAS1 DUSP5 EWSR1 ZNF136 MAP3K2 PPIL3 LGALS3 TOB1 GNA13 ZNF267 CTTNBP2NL SERTAD1 RAB5A CDC42EP3 LRP12 BRWD1 KPNA4 MAFK DNAJB9 CYTH1 NAA15 C1orf52 CNOT8 SPATA5L1 EHD4 TRIM36 MED17 PIM3	down	***
GSE18893_TCONV_VS_TREG_24H_TNF_STIM_UP	0.0000000	0.0000000	0.9759947	0.5331962	2.380395	164	HELLS TICRR TROAP CCDC34 C21orf58 CMTM1 PRIM2 BRCA1 DEPDC1B CDCA7 GINS1 RACGAP1 SLC27A2 PTTG1 CDC6 FIGNL1 UHRF1 MCM4 MCM2 CDC25A MYBL2 CCNF RCCD1 COQ3 CDT1 RANBP1 NUDT1 C19orf48 KIF15 KNTC1 NUP155 POLA2 MCM7 TTLL12 CDCA5 PRKDC CHAF1B ACTL6A RAD51AP1 SPC24 BRIP1 CAD ETFA COQ9 PSRC1 CKS1B FAHD2A CENPJ GMNN GOT2 E2F1 TRAP1 SAPCD2 ETFB DDT RTCB RNASEH2A CHCHD2 ILF2 CDC23 GSS NMRAL1 SLC37A4 C1orf131 CHTF18 ESCO2 MRPL4 PKP4 BCL2L12 POLD1 CABLES2 VPS25 DCUN1D5 WDR34 PPCDC MRPL41 GINS3 LSM4 ERGIC3 CBR1	up	***
GSE22886_NAIVE_CD4_TCELL_VS_DC_DN	0.0000000	0.0000000	0.9325952	-0.4435788	-2.365505	182	SLC31A2 ACP5 STAC MNDA LIPA FLVCR2 ARL8B PRKAR1A NCF2 AVPI1 SPG21 MAN2B1 CLEC7A IFI30 ANXA5 NFE2L2 GRN LAMTOR3 ATP6V1B2 CD58 CST3 ZMIZ1 MTMR6 DUSP3 PPT1 SDCBP LIMS1 YBX3 SLC7A8 CEBPA ATP6V1D CLIC4 LY96 ITGAX VIM M6PR TM6SF1 PLEKHB2 ZMPSTE24 HTT TM9SF2 CALM2 PI4K2A GLB1 VAMP3 PSEN1 PGD RAB31 ATP6V0B CYCS IFNGR1 CSTA TBC1D12 STX7 ZNF804A SNX1 PLCG2 CD74 GNG5 EXOC1 CCR1 FCGRT NPTN CLASP2 ZNF267 RXRA OPN3 MGAT2 DAPK1 STAM2 GLRX2 CTSC SNAP29 CREG1 WDFY3 RNH1	down	***
GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN	0.0000000	0.0000000	0.8513391	-0.4472588	-2.342196	157	SCN4A OLR1 NUP54 RAPGEF2 PTPRE CD44 HCAR2 CCRL2 MYD88 AGPAT4 IGSF6 CCNL1 RBM7 SBDS SDE2 BTG2 FOXP1 TREH CLN5 NFE2L2 TFEC AGO3 MEFV PTAFR PLAUR TNFSF15 KLF7 NFKB1 IRAK2 CCL4 PNRC1 PLEK DSE PIK3R5 NCKAP5 IKZF5 LMBRD1 FAM102B HCK NINJ1 MITF PTGER4 SKIL MALT1 RC3H1 GRIA1 REL BTBD7 EHD1 GSAP KCNA3 GNA13 PDE4B GTF2B RNF2 ICAM1 NLRP3 CCR9 MEX3C TRAF1 RND1 NFKBIA EDN1 DOCK10 MCOLN2 SAMSN1	down	***
GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN	0.0000000	0.0000000	0.8986712	-0.4400620	-2.335408	176	ACP5 CD52 SLC12A6 MNDA CCDC88A MYADM CITED2 BMPR2 MANBA CD9 FUCA1 AVPI1 TXNIP DPEP2 NCEH1 MCTP1 CD5 SIRPB2 ASAH1 ITGA5 LITAF TTYH2 RNASE1 LAIR1 RGCC NFE2L2 GRN SPTBN1 ZFYVE16 SORBS3 ZMIZ1 CPED1 MSR1 CYBRD1 ARRB1 AHNAK SDCBP CPVL ITM2B RRM2B ID3 TPP1 PLBD1 TMBIM1 TLR4 LBH ARHGAP9 PRCP PDK4 ELF1 CTSS NEK7 UTRN AQP3 MITF GCNT4 TPP2 SIGLEC1 TIMP2 RGS2 BNIP3L RTN1 ARRB2 IQSEC1 ESYT1 NLRP3 METTL7A DAPK1 ANXA11 CAMSAP2 CREG1 TLK1 IL16 LYZ ARRDC2 MDS2 CLEC4E C5 ZYX	down	***
GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN	0.0000000	0.0000000	0.9653278	0.5196337	2.330988	173	TRIP13 FOXM1 KIF20A FAM81A TICRR PARPBP MCM10 NEK2 XYLB CENPF TG MND1 PBK KIF18B DEPDC1B TTK RACGAP1 E2F8 ANLN GMPS ASPM STIL PLK1 NUF2 CDC6 TPX2 E2F3 CCNB2 FIGNL1 UHRF1 SPATS2 MYBL2 CCNF DTL MELK EXO1 CEP55 BUB1 TOP2A AURKA IFT43 KIF2C POC1A CLSPN CXCR5 MMS22L CDCA5 KIF11 FANCD2 CDC25C LIG1 CHEK1 AHCY RAD51AP1 SPC24 PERP CKS1B CDKN2C C12orf75 NUSAP1 PLOD2 CDK1 BIRC5 ARPC1A GMNN DNA2 FEN1 LRRC42 RECQL4 CCNE1 TUBG1 FAH ALDH7A1 SNRPA KIF22 MFSD2A ESCO2 SAP30 FBXO44	up	***
GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN	0.0000000	0.0000000	0.9101197	-0.4340567	-2.319514	191	SLC31A2 LPIN2 FABP4 SNX10 BMP2 EGR2 OTUD1 PDE1B CITED2 SLC15A3 BCL2A1 IL1RN IGSF6 IER2 CCNL1 RBM7 HBEGF ADAM17 SDE2 BTG2 SLC7A11 CLN5 PPP2R2A NDEL1 SLC25A37 TFEC SRGN MCL1 TIPARP SLC7A2 IL10 MAP2K3 CSRNP1 STAT5A RAB12 AHNAK AOC3 PLAUR COQ10B ID3 VASP STX3 SOCS5 KLF7 CLIC4 CXCL2 ATF3 IRAK2 C9orf72 GSDMA ID2 DUSP1 SPRYD7 USP16 PTH1R RPS6KA2 AREG KCTD12 DENND4A CLN3 SLC3A2 CD74 IRF5 GNA13 GTF2B VASH1 NLRP3 TBC1D1 KATNA1 EDN1 B3GNT2 MCOLN2 TLK2 MT2A DNAJA2 CSF2 SLC16A10 HERPUD1 EGR1 SERPINE1 ZNF800 HIPK1 DCUN1D3 ZFP36 CD69 SERP1 IRF1 NFIL3 HIVEP1 IRF4 EBI3 DUSP2 C15orf48 SENP6 ST3GAL1 SLAMF7 FEM1C TANK	down	***
GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN	0.0000000	0.0000000	0.8870750	-0.4374610	-2.305936	172	GCOM1 SLC12A6 PECAM1 LRRC8C PTPRE TUBB1 CTSW TBXA2R CBL PPM1D PDE2A SEMA6D C1orf21 ABCG2 CYB561A3 TMEM123 AKT3 FLI1 CCDC82 MPEG1 TCP11L2 STK17B DENND3 LAPTM5 PDE3B SELL HPSE KLRD1 N4BP2L1 AFF1 ARHGDIB HEXB EMP3 MYLIP CREBRF S1PR4 CTSS HCST ETS1 MSRB3 TYROBP GMFG FRYL N4BP3 LPCAT2 AP3B1 RASSF2 IP6K1 KLF2 C19orf38 CD1D DCK BAZ2B SERINC3 HELZ JUND BMP2K SELPLG BNIP3L CDC42EP3 SSH2 ABI3 CD3G CYTH1 CCND3 LPAR6 CNN2 BANK1 ARHGEF18 CDON CNR2 LNPEP PLEKHA2 RNF167 PIK3CG SIGLEC10 MAP4K2 RCSD1	down	***
GSE27434_WT_VS_DNMT1_KO_TREG_DN	0.0000000	0.0000000	0.8986712	-0.4331834	-2.305353	184	SMAD6 CXCL3 IL1A CPEB2 IL1B EGR2 GTF2E2 IL1RL1 IL1RN MOB1B IER2 TRA2B SLC25A17 CSRP1 BTG2 EIF5 MAP3K8 PAG1 PPP3CA NR4A1 NFE2L2 NDEL1 SRGN BTG3 UBE2D3 ATP6V1H PDGFA RHOB IL10 LIN7C PLAUR STX3 SOCS2 PDE8A CDKN1A CXCL2 SELP DUSP1 INHBA DSTN PROCR SPIN1 ETF1 SGK1 SOCS3 KCTD12 JUNB DNAJA1 EPC1 AK1 PPP1R15A WTAP IFRD1 EEA1 CD83 DDX5 GMFG ATP13A3 FOS RHOQ PELI1 EHD1 TGIF1 CD86 PIM1 STK40 ETS2 IST1 ICAM1 TNFAIP8 SERTAD1 HSP90AA1 ARIH1 RBM18 HNRNPK NFKBIA PTEN MCOLN2 TNFSF9 ATF4 PPP1CB YTHDC1 EGR1 SERPINE1 CLEC4E ZFP36 EFNB2 SRSF11 UBE2N DLD IRF1	down	***
GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000000	0.0000000	0.8634154	-0.4385941	-2.299748	166	PNPLA6 SWAP70 PECAM1 CD55 GPR65 PTPRE LRRFIP1 COQ2 GFOD1 BCL2A1 FUCA1 FRAT1 TGFBR2 TRIB1 FGR TACC1 ASAH1 SERINC1 MAP3K8 ANPEP SLC7A11 IL18R1 ATP6V1B2 ZMIZ1 PTPN12 EVI2B PTAFR THBS1 ERP44 PNRC1 CLK4 SMAD7 ADIPOR2 GNAQ CMTM6 SNN TMEM9B MCMBP AREG PSEN1 PGD CRNKL1 SEC14L1 HK3 PPP1R15A RNF24 RALB PPM1F ACSL1 FOS ATP6V0D1 RHOQ PELI1 TNFSF13 MBP CHIA TFEB EHD1 CTNNAL1 APLP2 GABARAPL1 CCNH SELPLG EPN2 MEGF9 OSER1 KIT PTEN CREG1 RABGEF1 KAT5 CHP1 AOAH RB1CC1 KBTBD11	down	***
GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN	0.0000000	0.0000000	0.8634154	-0.4333291	-2.295569	175	SLC47A1 MNDA FBP1 PTPRE LIPA TRPV2 LMO2 CLEC10A STX11 ALAS1 NCF2 CD9 AGPAT4 FRAT1 SLC11A1 EPB41L3 ZEB2 CLCF1 MAN2B1 CD33 LMNA ITGA5 IFI30 GRN TLE4 SDCBP ACSL3 DAB2 PLBD1 CLIC4 ITGAX FCER1G GCA CLIP4 IL7R PI4K2A NCKAP1L NINJ1 RPS6KA2 PRCP VAMP3 C1QA RAB31 HK3 CTSZ IFNGR1 RHOQ SLC22A1 ATG3 SAV1 MILR1 FPR2 CD81 APLP2 LGALS3 GABARAPL1 CCR1 NPTN TSPO MOB3B PDLIM5 SLC31A1 CEP170 RTN1 MS4A4A ALDH2 SLC2A9 MEGF9 SCPEP1 SOAT1 DAPK1 GLUL CAMSAP2 THEMIS2 CREG1 EHD4 RNF13 LYZ	down	***
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP	0.0000000	0.0000000	0.8634154	-0.4332196	-2.294988	175	SIK1 CITED2 CRY2 ELF2 YPEL5 DYRK1A FRAT1 TMX4 CCNL1 TXNIP ANXA1 ATP2B1 SH2B3 UBL3 BTG2 KLF6 STOM JAM3 RGCC TMEM123 NDEL1 TMEM41B CLK1 TIPARP MOAP1 KIAA0513 COQ10B LEPROTL1 KLF11 MED6 KLF7 MGAT4A CLK4 PER1 DUSP1 CCDC59 ARL4A IL7R VCPKMT MYLIP KLRB1 SGK1 HECA PLK3 JUNB PTGER4 PIK3R1 MBNL2 GPR183 ENTPD4 UVRAG TSPYL1 FOS PELI1 KLF2 PTP4A1 YTHDF3 FOSB TSC22D1 IRS2 ZNF136 FCGRT TOB1 KANSL2 HAUS3 RLF CXCR4 EPHA4 NLRP3 CREBBP RASSF8 DNAJB9 RORA DAZAP2 NR3C2 NUP160 PPP1CB ARHGEF18	down	***
GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN	0.0000000	0.0000000	0.9436322	0.5066900	2.290496	188	TRIP13 LINC00342 FOXM1 CDC45 BDH1 BUB1B CCNB1 CENPF TIMELESS FAM153B TTF2 NDC80 PRIM2 PHGDH TTK GINS1 CDK4 GTSE1 SLC27A2 GMPS POLE STIL CENPA ESPL1 CDC6 TPX2 UMPS GLDC ZWINT NME1 RANBP1 MELK HMMR EXO1 NUDT1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A CCT5 NUP155 KIF2C AKAP1 KIF11 GPSM2 CDC25C LIG1 CHEK1 AHCY PKMYT1 BLM SKP2 CKS1B EFCAB11 TMEM106C CDK1 POLE2 ATIC OAT NPM3 UNG TRAP1 SPAG5 ETFB LAPTM4B RNASEH2A NET1 FANCG CCNE1 TUBG1 DLGAP5 GSS ALDH7A1 SLC37A4 TK1 DTYMK ANP32E KIF20B	up	***
GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN	0.0000000	0.0000000	0.8634154	-0.4293781	-2.283191	185	EPAS1 SLC31A2 HVCN1 LTA4H CAT MIR22HG ENG CD9 LILRB3 ACER3 SH2B3 B3GNT5 MCTP1 SLC7A7 ARSB RASGRP4 GNGT2 MAP3K8 RNF144B STOM IL18R1 ADAMTSL4 PTPN12 FABP5 CFD LIMS1 PIP5K1B FUT7 TMED5 DENND3 LY96 CDKN1A C9orf72 TM6SF1 ZMPSTE24 SLC6A6 TM9SF2 GNAI2 EMP3 VAMP3 RNF149 PGD SNAP23 CTSZ ATP6V0B CCDC50 GSTO1 GRB2 RAB8A REL AP3B1 RALB WDFY4 TNFSF13 DGKG AKIRIN2 PEA15 DUSP5 TGFB1I1 PDLIM1 GALC MEIS1 RGS2 NBN RTN1 CEBPD ACTB GLUL PDE4A LYST TMCC3 FEZ2 SLFN11 IRF2 CYBA HERPUD1 CHP1 CSF2RB SH3BGRL3	down	***
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN	0.0000000	0.0000000	0.8513391	-0.4309259	-2.282837	175	WEE1 CXCL3 CXCL16 SOWAHC IL1B CCRL2 BACH1 CITED2 FOSL1 IDI1 SLC15A3 NUDT9 BCL2A1 TRIB1 CLCF1 MAP3K8 PPP2R2A SRGN MCL1 LRP4 CSRNP1 LRRC57 MEFV LAPTM5 CDKN1A C9orf72 CCL4 IGFBP2 DUSP1 PLEK MAFF CMTM6 RASGEF1B LACC1 SRF NRROS NINJ1 AREG IL6 RYBP SOCS3 ETV3 JUN CUL4A FOXN2 PPP1R15A PTGER4 DHX15 ENPP4 IFRD1 DDX5 GRASP HNRNPD EHD1 TGIF1 TESK2 DUSP5 IRS2 PCDH17 TAGAP STK40 PDE4B ETS2 GEM ICAM1 SERTAD1 IER5 CXCR4 HNRNPK EPHA2 TRAF1 NFKBIA MRPL32 ANXA11 PURB PIM3 YTHDC1 JDP2 EGR1 CHP1	down	***
GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN	0.0000000	0.0000000	0.8634154	-0.4293529	-2.278575	176	MS4A7 GIMAP8 MIR22HG PTPRE RRN3P2 BACH1 YPEL5 TET2 ZEB2 ATP2B1 UBL3 LATS2 SERINC1 MS4A1 C1orf162 ZFYVE16 TCF7L2 PTPN12 TCP11L2 RNFT1 PLEKHM3 ZFAND5 THBS1 SCAF4 SSH1 MGAT4A C9orf72 PNRC1 LBH CLK4 PLEK PPP2R5C CUL5 EFR3A BTG1 CREBRF FRY NXF1 HECA ETV3 DDX17 TREM1 RABGAP1 CSTA FBXO11 PNPLA8 FAM43A CD7 OGFRL1 RNF146 BTBD7 BAZ2B ZNF844 MAP3K2 HBP1 APLP2 ADPGK PHF11 ANKRD12 ATAD2B IST1 CDC42EP3 CXCR4 TRAPPC8 EPHA4 NLRP3 DDX59 CREBBP STK4 FNIP2 TMCC3 THEMIS2 DAZAP2 SLC35A1 ZBTB44 ARRDC2 CBX7	down	***
GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN	0.0000000	0.0000000	0.8513391	-0.4334980	-2.272677	171	PAN3-AS1 ZC3H12C RRN3P2 OTUD1 BACH1 YPEL5 NCF2 TET2 FRAT1 ABCB1 ZEB2 AVPI1 ATP2B1 UBL3 SERINC1 PICALM DACH1 AKT3 ZFYVE16 SRGN EPM2AIP1 TCF7L2 ZSWIM6 TCP11L2 PLAUR THBS1 SOCS5 LAPTM5 PDE3B NR1D2 C9orf72 PNRC1 CLK4 DUSP1 IL7R BTG1 CREBRF HCAR3 FRY HECA USO1 IFNGR1 CSTA CCR7 PNPLA8 GPR183 IDS OGFRL1 TSPYL1 PELI1 FOXO3 TGIF1 FAM228B BAZ2B HBP1 APLP2 KYNU N4BP2L2 RGS2 SLC43A2 CXCR4 EPHA4 SIK3 NLRP3 CREBBP METTL7A PAIP2 THEMIS2 ZBTB44 ARRDC2 DMXL2 ZNF106 ITGB1 RB1CC1 ZFYVE1 ZFP36 SLC26A11 PIAS2 TSC22D2 ATP8A1 CCPG1 RAB11FIP2 SIRT1 DUSP22	down	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP	0.0000000	0.0000000	0.8390889	-0.4310974	-2.260439	166	SC5D DENND5A SECISBP2L MIR22HG ST6GALNAC3 CITED2 BMPR2 PLEKHA1 INPP5A YPEL5 GNPTAB PDCL HEG1 TXNIP ZBTB4 DPEP2 FBXO7 PTPRM ASAH1 SPTBN1 SOX7 PPP3CC FBXL5 EVI2B ITPRIP SGTB PSTK MGAT4A CTBS C9orf72 DUSP1 IL7R UBASH3B PIK3R5 C16orf54 MYLIP SGK1 MAML2 AQP3 SNX29 MAP4K4 JUNB ATXN1L PNPLA8 KLF2 YPEL2 XYLT1 BIN2 NAP1L5 FAM204A VAV3 ABHD13 TSC22D1 IRS2 KCNA3 GABARAPL1 HELZ GPX3 ABL2 CGRRF1 EPHA4 TTC32 OSER1 TTC28 DNAJB9 ZFAND2A LYZ TNFSF8 NR4A2 FAM8A1 ASH1L-AS1 SPTY2D1 ATP8A1 MEF2D ITGA6 BBIP1 CEP68 PTGS2 YOD1 CD4 NFKBIZ MYO1F	down	***
GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN	0.0000000	0.0000000	0.8266573	-0.4291470	-2.258648	169	PPARG SOWAHC DCSTAMP MIR22HG PTPRE LPL GFOD1 ST3GAL6 CORO1C NEDD4L FOSL1 GPCPD1 TBC1D7 TBC1D2 ZBTB2 MOB1B TRIB1 CNST RRAGC ZBTB21 SPRY2 CRTAM TXN ATP6V1H TMEM38B ATP6V1B2 RHOB FBXL5 NRARP MOAP1 ACSL3 ANKRD10 DAB2 TNFSF15 STX3 ATP6V1D ITGAX ATF3 LBH ZBTB43 FKBP15 MMP19 NRROS SERTAD2 BCAR3 SGK1 SH3BP5 TMEM251 SIGLEC15 SNX9 SLC3A2 RNASEK AKIRIN2 TSC22D1 COL15A1 BRI3 CCR1 CRY1 GNA13 GEM RLF CDC42EP3 TEX10 HAVCR2 MAFK EDN1 FNIP2 RABGEF1 GPALPP1 SERPINE1 NR4A2 SLC19A2 LHFPL2 HES4 RB1CC1	down	***
GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN	0.0000000	0.0000000	0.8513391	-0.4270824	-2.256016	174	PPARG SOWAHC DCSTAMP PTPRE LPL EGR2 GFOD1 ST3GAL6 CORO1C GPCPD1 TBC1D7 ZCCHC2 TBC1D2 MOB1B TRIB1 RRAGC LINC01010 SPRY2 CRTAM ATP6V1H TMEM38B ATP6V1B2 RHOB FBXL5 MOAP1 ACSL3 ANKRD10 DAB2 TNFSF15 STX3 ATP6V1D ITGAX ATF3 ATP6V0D2 LBH ZBTB43 PPP2R5A UBASH3B FKBP15 HTRA4 EFR3A PI4K2A RASGEF1B MMP19 CLN8 NRROS SERTAD2 BCAR3 SGK1 PHACTR2 SH3BP5 TMEM251 EEA1 SIGLEC15 SNX9 SLC3A2 AKIRIN2 COL15A1 LGALS3 BRI3 CCR1 CRY1 GNA13 GEM RLF CDC42EP3 TEX10 HAVCR2 AMZ2P1 MAFK EDN1 FNIP2 MT2A RABGEF1 SERPINE1 NR4A2 LHFPL2 HES4 MT1E PPFIA1 TRPM7	down	***
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP	0.0000000	0.0000000	0.8390889	-0.4295975	-2.255453	167	SC5D SGK3 RBMS2 GPR65 RAPGEF2 PTPRE IBA57 DDX6 CRY2 IDI1 YPEL5 ZBTB2 ABCB1 ATP2B1 CLCF1 DNAJC3 LTBP4 UBL3 CACNA2D2 ITGA5 LUZP1 RNF125 NFE2L2 TCF7L2 ITPRIP LINC00528 ARNTL NR1D2 PER1 DNTTIP2 SMAD7 ELMSAN1 IL7R TP53BP2 IKZF5 CNOT6L TOPORS DCTN6 ETV3 PLK3 IFNGR1 EPC1 PIK3R1 HSPA13 HERC1 RC3H1 ENTPD4 REL FAM177A1 ACSL1 AGFG1 PTP4A1 FOXO3 FOSB TGFB1 ZRANB1 ZBTB11 MIA3 MAP3K2 PDE4B SERTAD1 EPHA4 PSME4 RNF38 C1orf115 LYZ RABGEF1 RB1CC1 ZFP36 TBC1D23 FAM53B PIAS2 CCDC93 TSC22D2 CHKA SETD2	down	***
GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN	0.0000000	0.0000000	0.8513391	-0.4245004	-2.255229	179	ACP5 KMO SLC47A1 MNDA DCSTAMP PTPRE LIPA LPL CCDC88A CRY2 SLC15A3 P2RY13 MEF2A MARCO MANBA CD9 TEX2 KIAA0355 PLA2G7 ASAH1 GM2A RNASE1 HLX SIRPA ZFYVE16 KDSR ARRB1 CCL22 PLAUR PLBD1 LY96 CDKN1A DCHS1 MAFF HEXB HCK KANK1 CTSS CYB5R1 C1QA KCTD12 CTSZ TYROBP IFNGR1 CSTA SNX2 IRF8 TNFRSF10B ACSL1 FOS RHOQ TIMP2 TCF4 TSC22D1 GOLGA8H LGALS3 FCGRT KYNU PLA2G15 IL18 RTN1 CXCR4 LRP12 NLRP3 ALDH2 SCPEP1 CTSC MMD CREG1 LPAR6 FEZ2 LYZ SERPINE1 CTSH LHFPL2 FTL ATP1B1 FPR3 UBE2W WNT5A	down	***
GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN	0.0000000	0.0000000	0.8753251	-0.4227778	-2.254578	182	SLC31A2 KMO HMOX1 TSPAN4 OSBPL1A FABP4 MNDA FBP1 CYP27A1 CAT LIPA ENG LPL GFOD1 AQP9 CLEC10A SLC15A3 CD9 FUCA1 IGSF6 PILRA FGR AVPI1 MAN2B1 CD33 SLC7A7 LMNA CLEC7A IFI30 ANPEP RNASE1 STOM SIRPA GRN TFEC APOC1 TUBB6 CEBPA PLBD1 LY96 CDKN1A ITGAX TM6SF1 INHBA BACE1 HCK C1QA VAT1 RAB31 HK3 CTSZ TYROBP ACSL1 RHOQ TNFSF13 SORT1 TIMP2 CD86 APLP2 CCR1 FCGRT TFPI RTN1 MS4A4A RIPK2 NLRP3 TBC1D1 SCPEP1 GLUL SIGLEC9 CTSC CREG1 LPAR6 PAPSS2 C1QB LHFPL2 TREM2 FTL S100A8 QSOX1 FPR3	down	***
GSE14415_INDUCED_VS_NATURAL_TREG_DN	0.0000000	0.0000000	0.8870750	0.5046353	2.250807	162	TRIP13 CDC45 BUB1B CENPF IGF2BP3 MPP6 PBK BRCA1 DEPDC1B CDCA7 TTK GINS1 E2F8 KIF14 NOL12 ASPM PLK1 NUF2 CDCA8 CENPA ECT2 TPX2 CCNB2 MCM2 NME1 MELK HMMR EXO1 NUDT1 KIF23 CEP55 MKI67 KIF15 BUB1 TOP2A SAE1 KIF2C MPO CLSPN WDHD1 RAD54L KIF11 GPR146 MCM3 LMNB1 CDC25C CKAP2L DCTPP1 SPC24 ALDOA INCENP CKS1B NCAPG2 ASF1B ANAPC5 CDK1 CENPH BIRC5 ADAP1 NCAPG NEIL3 EZH2 DLGAP5 TACC3 AARSD1 KIF22 ARL6IP4	up	***
GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN	0.0000000	0.0000000	0.8753251	0.5015682	2.239196	164	ALDH3B2 TRIP13 HELLS KIF20A HJURP CPLX2 CDC45 FANCI TROAP BUB1B NEK2 CCNB1 CENPF FAM153A PHGDH GINS1 RACGAP1 E2F8 IFT122 KIF14 POLE ASPM PTTG1 ESPL1 CCNB2 TYMS PRC1 DTL ZWINT HAUS5 MELK HMMR EXO1 MUC6 STRA6 CEP55 CHAF1A PAQR4 MKI67 TOP2A AURKA POLA2 RRM2 PRKDC RAD54L KIF11 GPSM2 DNAJC9 RAD51AP1 REPIN1 NCAPG2 NUSAP1 CDK1 TNFRSF21 GMNN NCAPG EZH2 SPAG5 DNMT1 CDK3 TUBG1 DLGAP5	up	***
GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_DN	0.0000000	0.0000000	0.8140358	-0.4249888	-2.236763	169	FCN1 CD101 PHACTR1 LTA4H THBD HSD17B11 INPP5K SRSF7 YPEL5 FRAT1 IER2 TOE1 ANXA1 CHMP1B NR4A1 CD37 CPED1 EVI2B SNAI1 TLE4 MEFV BST1 KLF4 CDK9 MYO15B TLR4 DUSP1 RSL24D1 MAPRE2 RPL17 MYLIP ELF1 OASL SRSF3 SFTPB JUNB PIK3R1 GPR183 TAGLN2 SNRK FOS KLF2 PTP4A1 ICAM2 SRSF6 FOSB FAM204A RPL21 APLP2 JUND EIF3F LDLRAD4 NEK1 CEBPD CXCR4 RPS13 S100A4 ICAM3 P2RX1 C5AR2 CRTAP NR4A2 CX3CR1 EIF3L ZFP36 CD69 FXYD5	down	***
GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN	0.0000000	0.0000000	0.8390889	-0.4208283	-2.235721	179	ACP5 HMOX1 MNDA PTPRE LIPA EGR2 CD44 BACH1 CORO1C PLEKHA1 CLEC10A NCF2 CD9 SLC11A1 EPB41L3 SYNC FGR AVPI1 MMRN2 PLA2G7 SPG21 ARSB GM2A CLEC7A IFI30 HLX SIRPA RGCC TNS1 SPRY2 TMEM41B TFEC ATP6V1H PTPN12 CCL22 KIAA0513 DAB2 SLC7A8 CEBPA CDS2 PLEK DSE PI4K2A ARHGAP17 VAMP3 SGK1 CTSS C1QA TYROBP HOMER1 PPM1F RRAS TNFSF13 RIN2 SAV1 TSC22D1 CD86 CD81 APLP2 FCGRT PLEKHO2 MFSD12 CLCN6 SLC31A1 ELOVL1 RIPK2 TBC1D1 SCPEP1 TTC28 SYNPO2L KIF1B DOCK4 NR3C2 LPAR6 RNF13 ATP6V0A1 SERPINE1 C1QB BHLHE41 LHFPL2 FUS	down	***
GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN	0.0000000	0.0000000	0.8390889	-0.4198510	-2.232531	185	DENND5A ZC3H12C SNX10 LYL1 HSD17B11 LMO2 MYADM INPP5A CD9 WBP4 CD22 GGA2 ANXA1 SPG21 PTS UBL3 SLC7A7 ENTPD1 RAP1A MAP3K8 PBX3 MS4A1 SRGN UBE2D3 MCL1 RAB14 TUBB6 TIPARP EPB41L2 ARRB1 AHNAK MPEG1 RNFT1 KLF4 PLAUR ROCK1 PLBD1 FAM49B PDE8A PLEKHB2 EPS15 EVI2A HLA-DQA1 HCK SACM1L MTPN PKIG ASNSD1 LIMD1 RAB31 ETS1 SNX2 STX7 EEA1 CD83 NDST1 PLCG2 RHOQ CD74 STXBP3 TCF4 AP1G1 VAMP4 SBF2 ACADL ADAM10 PPID IST1 SPIB VPS4B ARIH1 S100A4 CD19 CTSC DNAJB9	down	***
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_DN	0.0000000	0.0000000	0.8390889	0.5083845	2.228126	140	TRIP13 FOXM1 KIF20A HJURP TROAP NEK2 CCNB1 CENPF ZFHX4 PBK KIF18B DEPDC1 GINS1 ANLN ASPM PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 TBX19 TPX2 CCNB2 PRC1 SLC7A9 DTL KIF27 MYL6B DNAH14 CLDN1 MELK HMMR CEP55 MKI67 TSGA10 MAP10 AURKA METTL7B MYO10 C1orf226 RRM2 CDCA5 MGLL PLOD2 CDK1 BIRC5 PSAT1 ZNF789 SPAG5 DIAPH3 ITGA2B BBS5 TUBG1 DLGAP5 ZMAT5 RGS22 ZNRF2P1 C9orf152 TK1 ESCO2	up	***
GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP	0.0000000	0.0000000	0.8390889	-0.4197347	-2.225722	181	CD300LF SWAP70 MCOLN1 PECAM1 SOWAHC LTA4H KCTD9 SH2D3C LMO2 TMOD3 BACH1 KIAA1109 INPP5A DYRK1A FUCA1 SLC11A1 HEG1 SLC44A2 ASAH1 RNF144B SLAIN2 GPBAR1 RAB14 EVI2B CYBRD1 MAP2K3 MTMR6 DENND6A REST PTPRC CDS2 PAPSS1 SFTPD CLK4 FCER1G MBD2 SLC6A6 N4BP1 UBASH3B MRVI1 CMTM6 ZDHHC20 RBP7 NEK7 CPEB4 HK3 OSTM1 NXPE3 SP3 PIK3R1 APH1B PRORSD1P RRAS ING3 KIAA0232 FPR2 DUSP5 ZBTB11 SOD2 ME2 SESN1 IER5 DHRS12 SCPEP1 DAPK1 DUSP7 P2RX1 DAZAP2 SPOPL MAN1C1 ZBTB16 DUSP6 KCNE1 LNPEP ITGB1 HEY1 CD79B GPR137B MAN1A1	down	***
GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_DN	0.0000000	0.0000000	0.8513391	0.5016727	2.225327	156	TRIP13 CDC45 BUB1B IGF2BP3 MPP6 PSPH PBK BRCA1 GINS1 RACGAP1 E2F8 KIF14 AP1S1 PLK1 NUF2 CDCA8 CENPA TPX2 CCNB2 FIGNL1 UHRF1 MCM2 PRC1 DTL NCAPD2 NUDT1 KIF23 CEP55 KIF15 KNTC1 BUB1 SAE1 CLSPN RRM2 WDHD1 KIF11 MCM3 CDC25C CHEK1 THYN1 MAD2L1 AHCY DCTPP1 SPC24 DSCC1 BRIP1 ALDOA NCAPG2 CBX5 ANAPC5 CDK1 CENPH BIRC5 NCAPG NOP2 CENPP PA2G4 DLGAP5 TACC3 SNRPA AARSD1 ARL6IP4 ANP32E ATAD5 CDC7 PPP1R8 LRRC59 MCM6 LANCL2 ATAD2 TCERG1 CCNA2 SHCBP1 COX5B ARHGAP11A WDR76 SMC2 ZMAT2 EPSTI1	up	***
GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP	0.0000000	0.0000000	0.8513391	0.4977403	2.224655	165	HELLS CDC45 CCDC34 CENPF SRGAP3 BRCA1 TTK KIF14 POLE ASPM PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA ECT2 TPX2 CCNB2 FIGNL1 RBBP8 PRC1 XDH NCAPD2 CXCL10 HMMR MKI67 KIF15 BUB1 AUNIP TOP2A KIF2C MCM7 CLSPN RRM2 WDHD1 HOOK1 KIF11 MCM3 CDC25C LIG1 CHEK1 MAD2L1 NEB RAD51AP1 BRIP1 INPP4B INCENP CKS1B NCAPG2 PLOD2 CBX5 CDK1 CENPH NCAPG PSAT1 NEIL3 EZH2 ETFB OCIAD2 CCNE1 KIF22 ESCO2 LCLAT1 ATAD5 USP18 RPA1 MCM6 CKAP2 SUOX ANK3 CORO2A APOBEC2 CCNA2 PRIM1 DZIP3 PRR11	up	***
GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN	0.0000000	0.0000000	0.8140358	-0.4108506	-2.197374	183	ARHGAP31 SWAP70 EDNRB HVCN1 ZC3H12C IL1B PTPRE EGR2 HCAR2 CCRL2 LONRF1 FXYD2 SLC15A3 STX11 ALAS1 BCL2A1 PILRA SEMA6D HBEGF ADAM17 PLXNA2 ANXA5 SERPINB9 NFE2L2 PDGFA RHOB SLC7A2 SLC7A8 VASP KLF7 CXCL2 ATF3 ID2 DUSP1 PLEK HTT UBASH3B KPNA3 TLL1 RASGEF1B PROCR IL6 IL2RB MTMR14 PLK3 JUNB RCAN1 SKIL PSTPIP2 MALT1 TAGLN2 ACSL1 SMPDL3B GSAP FPR2 FEM1B DUSP5 CD86 GPR84 PLEKHO2 GEM WDR1 RIPK2 NLRP3 TRAF1 EDN1 TNFSF9 NRP2 ATF4 SLC16A10 HERPUD1 JDP2 EGR1 CD70	down	***
GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN	0.0000000	0.0000000	0.8266573	0.4901804	2.195795	169	TRIP13 HELLS KCNK5 CDC45 GPT2 CCNB1 UBE2T PHGDH CDCA7 METTL1 TTK HILPDA TOMM34 ACAD9 ESPL1 RBBP8 UHRF1 MCM4 CYP27B1 DTL ACY1 LIG3 SHMT2 ZWINT AGK C19orf48 CHAF1A KIF3B AURKA POLD2 TTLL12 CHEK1 ORC6 PFKP TIMM50 FNTB BLM DDX56 THOP1 KNSTRN DDX51 POLE2 UCK2 NPM3 TRAP1 EZH2 NOP2 PA2G4 POFUT1 PDCD11 MRPS34 MAPK13 DPH2 MYBBP1A MFSD2A GINS2 MRPL4 SPAG1 TIMM13 CDC20 NPRL3 RRP9 BCL2L1 NOL6 UTP20 NOC4L CLUH GINS3 IL12RB2 SLC1A5 NEFH MED27 FARSA SUV39H2 NTMT1 ABCF2 ZWILCH TRIP6 ST20 SNX8 LIF POLR1A ALG1 PCBD1 TIMM44 SNRPC SFXN4 KCNK6 C9orf40 F5	up	***
GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP	0.0000000	0.0000000	0.8012156	-0.4141873	-2.194164	175	MCOLN1 PPARG LPL GFOD1 CORO1C GPCPD1 TBC1D7 ZCCHC2 TBC1D2 TRIB1 TXNIP EIF4A1 CNST FBXO7 RRAGC LINC01010 IFI30 CRTAM TMEM38B ATP6V1B2 RHOB FBXL5 FABP5 MOAP1 ACSL3 DAB2 TNFSF15 MAP1LC3B TMED5 STX3 ATP6V1D TMBIM1 ATF3 PPP2R5A UBASH3B FKBP15 CD300LB EFR3A PI4K2A MMP19 HEXB CLN8 NRROS TMEM9B BCAR3 SGK1 SH3BP5 HIC1 TMEM251 SNX9 KLF2 RNASEK CD164 TGIF1 COL15A1 LGALS3 TMEM70 BRI3 CCR1 GNA13 PLEKHO2 AMD1	down	***
GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP	0.0000000	0.0000000	0.8140358	-0.4137171	-2.193813	181	RAB11FIP1 PECAM1 LTA4H LIPA LRRFIP1 HSD17B11 BAIAP2 C5AR1 YPEL5 MANBA NEDD9 AGTPBP1 CASP9 TACC1 ASAH1 CLEC7A RAB33B NR4A1 CD37 RHOB FLI1 EVI2B SRSF5 KIAA0513 KLF4 ITM2B DENND3 PLBD1 COTL1 TLR4 CD302 DUSP1 EVI2A SPIN1 MYLIP ELF1 SF3B1 OSBPL9 IFNGR1 PTGER4 PIK3R1 RASSF2 SNRK PPM1F CELF2 KLF2 RUNX3 PHF3 ZBTB1 GOLGA8H CBFA2T3 CD86 MAP3K2 CSDE1 ADPGK RGS2 TSPO JUND GPX3 CCDC69 IQSEC1 CEBPD ALDH2 SCPEP1	down	***
GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_DN	0.0000000	0.0000000	0.8012156	0.4961681	2.187036	148	TRIP13 KIF20A HJURP MCM10 TROAP BUB1B NEK2 PRTFDC1 POLQ UBE2T KIF18B IFI27L1 DEPDC1B PLK1 NUF2 CENPA PTTG1 ESPL1 CCNB2 NBR2 MCM2 GLDC LIME1 COQ3 CLDN1 CEP55 RPL39L MKI67 EMC9 TSGA10 LGMN AURKA KIF2C CDCA5 KISS1R RAD54L MAD2L1 CKAP2L DPY19L1P1 MGLL DDX51 TMEM106C PLOD2 ASF1B EPHA1 BIRC5 C1orf112 PSAT1 NEIL3 FEN1 SSX2IP SPAG5 DIAPH3 ITGA2B NRGN CCNE1 DLGAP5 ESCO2 LIPC GNAZ DENND5B	up	***
GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP	0.0000000	0.0000000	0.8513391	0.4848113	2.178988	178	CDC45 BDH1 FANCI BUB1B NEK2 CCNB1 CENPF TIMELESS TTF2 NDC80 SORD PHGDH TTK CDK4 SLC27A2 PTTG1 GPI ESPL1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 ALDOC SHMT2 XPOT NCAPD2 CDT1 NME1 RUVBL2 HMMR KIF3B EEF1E1 TOP2A CCT5 AURKA POLD2 KIF2C RRM2 PKM KIF11 MCM3 AHCY RAB13 RAD51AP1 ALDOA THOP1 CKS1B TMEM106C CDK1 POLE2 NPM3 EZH2 TUBG1 GNPAT GALK2 RAD51D TK1 ASNS SAP30 ZBTB7B CDC7 AHCYL1 STAMBP FAM161A HAX1 FARSA PYCR1 CCNA2 PRIM1 VDAC1 ATOX1 VDAC3 SMC2 MTHFD1 TP53 PAICS BCAT2 ENO1 MUC1 NCAPH CYB5B CFI SRM BAG2 NIT1 GSTP1 VLDLR TOMM40	up	***
GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP	0.0000000	0.0000001	0.7749390	-0.4147739	-2.176315	161	WEE1 EDNRB FIG4 SH2D3C PLEKHF2 TMOD3 CRY2 S1PR1 MEF2A ALAS1 FBXO3 IL1RN PILRA GGA2 CASP9 LTBP4 SEMA3B RAPGEF4 SERINC1 HSPB1 PRELP PAG1 NFE2L2 NDEL1 AKT3 PER3 TBX4 NPNT FMO2 FUT7 USP2 CLIC4 ATG7 PER2 CADM1 VIM AXL CD302 DUSP1 ARL4A AKIRIN1 SNX3 RYBP PSEN1 ARL6IP6 CYP2A6 HSPA1B DNAJA1 HOMER1 TAGLN2 SLC25A24 CACYBP PPP2CB MR1 LDLRAD4 NEK1 CEBPD ESYT1 METTL7A SNAP29 IL16 DNAJA2 CEND1 RAP1GAP SDHAF2 SLC25A38 PRKCH NDFIP1 DNAJB4 DNAJB1	down	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN	0.0000000	0.0000000	0.8012156	-0.4127203	-2.176134	173	ACP5 FCN1 CD101 SIGLEC16 HHEX FABP4 MNDA LTA4H FBP1 GPR65 LIPA INPP5K SAMHD1 CD1C CD9 FUCA1 TEX2 GGA2 AVPI1 TXNIP CD36 TACC1 CLEC7A ZNF503 REV3L RNASE1 ABHD6 C1orf162 EVI2B TIMM10B PPT1 KIAA0513 SLC46A2 CD302 CPT1A RAP1GDS1 MPC1 UBASH3B CD300LB PRCP PDK4 RBP7 SLCO2B1 OASL UTRN GLUD1 LPCAT2 VMO1 GAS2L3 FOS SORT1 KIAA0232 CD1D GALC MFNG GNA13 MACF1 PLA2G15 SLC31A1 CALHM2 SLC25A20 PIP4K2A ARHGAP18 METTL7A CD1E DOCK10 RHOT1 LPAR6	down	***
GSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN	0.0000000	0.0000000	0.8266573	0.4875858	2.174188	163	TRIP13 TP63 DDX11 FOXM1 HELLS KIF20A CDC45 TROAP NEK2 CCNB1 CENPF PHGDH GINS1 E2F8 IFT122 KIF14 ASPM TPX2 CCNB2 TYMS CDC25A PRC1 PLS1 DTL ZWINT DZANK1 MELK EXO1 CHAF1A RPL39L MKI67 KIF15 AUNIP TOP2A AURKA POLA2 KIF2C RRM2 PRKDC RHOBTB3 KIF11 RAD51AP1 PKMYT1 BRIP1 REPIN1 NUSAP1 TMEM106C ASF1B CDK1 POLE2 TNFRSF21 UCK2 GMNN NCAPG EZH2 SPAG5 ABCA4 DNMT1 DLGAP5	up	***
GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_DN	0.0000000	0.0000000	0.8012156	-0.4101212	-2.158798	170	SLC31A2 EREG FCN1 HVCN1 KL EGR2 BACH1 INPP5A ARL8B TBC1D2 AGTPBP1 FUCA1 LAMP1 ARHGAP29 CD36 SPG21 B3GNT5 CARD16 SGMS2 ASAH1 HLX GPBAR1 TCF7L2 ARL11 EVI2B CFD TLE4 GCHFR CLIC4 CTSD UXS1 TLR4 EVI2A GCA CARS2 PINK1 LIN7A NCOA1 ZDHHC20 RBP7 FRY KIF13A NEK7 CPEB4 MAP4K4 TYROBP OGFRL1 ACSL1 RHOQ AZI2 CR1 ING3 DOK3 KIAA0232 SERPINB1 FPR2 GALC ATXN1 SOD2 TSPO NLRP3 UBE2D1 SCPEP1 PAK2 ITCH RHOT1 GRB10 TOX2 EVI5 DUSP6 CLIP1 KCNE1 ITGB1 PLXDC2 PPIP5K2	down	***
GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_UP	0.0000000	0.0000001	0.7749390	-0.4113915	-2.158567	161	EREG FCN1 OLR1 LTA4H CYP27A1 FYN CD44 BACH1 AQP9 FLVCR2 NCF2 CD9 RFTN1 CD5 PBOV1 BTG2 EIF5 ANPEP SLC7A11 LCP1 AKT3 PTGIR CCL22 NFKB1 PDE3B ATF3 PNRC1 ARAP3 DUSP1 HLA-DQA1 CRIM1 VWF HCK UTRN DDX17 JUNB CCR7 GLIPR1 CD83 GPR183 IDS PTGER2 CGGBP1 CST7 GRIK1 PPM1F MOB1A FOXO3 NAB1 GNG5 SOD2 KYNU PDE4B PHLPP2 TPT1 CXCR4 ITGAE TRAF1 SRSF10 NFKBIA DNAJB5 LYZ ZBTB44 AFTPH CSF2RB C5AR2 TMEM43 CLEC4E GNG11 LAMP3 HLA-DRB1 DDX21 IRF1 STARD5 CFLAR IRF4 MSC DUSP2 SLAMF7 IL10RA CYTIP TANK	down	***
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP	0.0000000	0.0000000	0.8012156	-0.4061983	-2.157997	179	SIK1 HSD17B11 CRY2 INPP5A MTMR10 YPEL5 DYRK1A FRAT1 TMX4 CCNL1 TXNIP ANXA1 DPEP2 ATP2B1 UBL3 RGCC TMEM123 NDEL1 TMEM41B CLK1 TIPARP EVI2B MOAP1 KIAA0513 LEPROTL1 KLF11 MED6 KLF7 MGAT4A LAPTM5 PER1 DUSP1 ARL4A MAPRE2 BTG1 MYLIP KLRB1 SGK1 AQP3 HECA CD48 JUN PTGER4 PIK3R1 GPR183 ENTPD4 TSPYL1 TNFRSF10B FOS PELI1 KLF2 PTP4A1 FOSB TRAPPC10 IRS2 ZNF136 TOB1 KANSL2 RLF TPT1 CXCR4 EPHA4 SIK3 NLRP3 RBM48 DNAJB9 CYTH1 RORA DAZAP2 NR3C2 NUP160 PPP1CB ARHGEF18	down	***
GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN	0.0000000	0.0000000	0.8140358	-0.4046317	-2.157809	182	CXCL3 SLC31A2 IL1A SWAP70 OLR1 ZC3H12C IL1B CCRL2 CDC42EP2 STX11 SEMA6D SLC44A2 ADAM17 ITGA5 SERPINB9 NR4A1 ZEB1 CSRNP1 STAT5A PTGIR CCL22 SPNS3 MEFV VASP NFKB1 IRAK2 CCL4 CCSER2 DUSP1 N4BP1 MAFF MOB3A RASGEF1B SNN HCK PKIG CHDH SOCS3 MTMR14 JUNB RCAN1 PPP1R15A PTGER4 CCR7 SKIL CD83 PSTPIP2 REL NOL7 DENND4A EHD1 FPR2 DUSP5 CD86 PIM1 GPR84 SOD2 TAGAP PLEKHO2 PDE4B ETS2 GEM ICAM1 NLRP3 TRAF1 NFKBIA TNFSF9 SAMSN1 MIER3 DNAJA2 SPATA13 FNBP1 HERPUD1 EGR1 CLEC4E ZFP36 CD69 HLA-DRB1 IRF1 B3GALNT2 FCHSD2 NR4A3 CFLAR PTGS2 JARID2 NFKBIZ DUSP2 RNF19B	down	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_UP	0.0000000	0.0000001	0.7881868	-0.4101730	-2.147604	160	IL1A DENND5A USP12 SOWAHC IL1B NR3C1 NEDD9 BCL2A1 AGPAT4 SCARF1 RFTN1 LRRFIP2 HBEGF HECW2 MTF1 TNIP3 RNF144B SLC25A37 AKT3 PTPN12 TBC1D9 PLAUR PRKD3 TNFSF15 MAP1LC3B DENND3 SOCS2 CLIC4 NFKB1 CXCL2 CCL4 DNTTIP2 PROCR KANK1 IL6 PGD SOCS3 SH3BP5 HRH1 TREM1 CSTA WTAP ELOVL7 OSM FSD1L TNFRSF9 ACSL1 MAPK8 SAV1 EHD1 GSAP FPR2 SOD2 PDE4B ETS2 CCL20 MIR155HG NBN IER5 CDC42EP3 DIXDC1 PLGRKT MAP3K4 BCAT1 NFKBIA RASSF8 TMCC3 PURB TRIM36 RABGEF1 MZT1 DCUN1D3 OSGIN2 MSANTD3 YRDC HEY1	down	***
GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP	0.0000000	0.0000000	0.8140358	0.4785316	2.147572	172	TRIP13 RUVBL1 CDC45 KIF18B PIF1 TBRG4 BRCA1 DEPDC1B MRPL46 IQGAP3 ASPM STIL ECT2 CCNB2 RAD54B TYMS UMPS CA12 SHMT2 NCAPD2 NME1 NDUFB8 KIF23 MKI67 QTRT1 BUB1 CCT5 KIF2C CLSPN MRPL3 MRPL27 PASK MCM3 LIG1 ZNHIT1 C7orf50 CBY1 DSCC1 PSRC1 NUSAP1 ASF1B POLE2 CENPH NUDT2 PSMB5 DNA2 PSAT1 RECQL4 DLGAP5 TAPBPL TACC3 SNRPA LMNB2 MNS1 GALNS ANP32E SGSM3 CNDP2 CDC7 NIF3L1 CDC20 STOML2 LRRC59 GPATCH4 BCL2L1 FANCM MCM5 TMEM147 NOC4L FFAR2 TSR1 NUP62 LRP11 CCNA2 PRIM1 SHCBP1 RFC5 HK2 RAD51 FARSB ARHGAP11A ACP1 NUBPL SEPHS1 PAICS	up	***
GSE45365_WT_VS_IFNAR_KO_CD11B_DC_MCMV_INFECTION_DN	0.0000000	0.0000002	0.7477397	0.4984567	2.139886	121	CEACAM1 TRIP13 FOXM1 KIF20A CYP19A1 CENPF FRK MND1 DEPDC1 NPY6R GINS1 E2F8 DAW1 ASPM OTOGL NUF2 CDCA8 PLD5 TPX2 CCNB2 BCL2L14 PRC1 TMEM132D DTL KHDC1 CLDN1 MELK HMMR CEP55 MKI67 TOP2A AURKA MYO10 REC8 SLC2A10 CDCA5 HELB CDC25C PAK1 CDK1 ENPP3 PSAT1 SPAG5 DLGAP5 ZNRF2P1 ARF5 TK1 GAS2 TSSK3 KDELR3 CDC20 UPK1B GADD45G BCL9 SHCBP1 ZNF462 MCU GNA14 CENPE UBE2C DCDC1 NLGN1 TK2 UMODL1 TMEM169 ESYT3	up	***
GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN	0.0000000	0.0000001	0.7749390	-0.4066715	-2.135088	167	CXCL3 IL1A USP12 ZC3H12C RAPGEF2 INSIG1 CCRL2 STX11 FAM49A ADA BTG2 MAP3K8 RNF144B TTYH2 ZNF697 BTG3 TCF7L2 CSRNP1 PLAUR PXDC1 DRAM1 KLF7 NFKB1 CDKN1A CXCL2 ATF3 ZBTB43 DUSP1 TP53BP2 SRF BTG1 HCAR3 IL6 SAR1A SOCS3 PLEKHA3 OASL ETV3 ARL5B STAT4 PLK3 JUNB PPP1R15A PTGER4 CCR7 IRF8 LYRM1 GPR183 FSD1L REL ACSL1 PELI1 FXYD6 EHD1 DUSP5 LRRC32 KCNA3 GEM ICAM1 ARAP2 IL18RAP TNFAIP8 MIR155HG RIPK2 NUP98 TRAF1 NFKBIA EDN1 LDLR NABP1 PIM3 NR4A2 DCUN1D3 HES4 DNAJB4 MT1E LAMP3 DAPP1 IRF1 NR4A3 CFLAR PTGS2 HIVEP1 NFKBIZ DUSP2 C15orf48 SLAMF7 RASSF5 IL10RA C2orf15 SLAMF1	down	***
GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000000	0.0000000	0.8012156	-0.4010921	-2.134566	184	SLC31A2 KMO SLC47A1 PECAM1 PPARG FBP1 DCSTAMP MIR22HG FCER1A FOSL1 PCOLCE2 C5AR1 SLC15A3 TBC1D2 CD1C CD9 FUCA1 WBP4 LAMP1 AGPAT4 IGSF6 FGR NUMB CD36 CD33 ABCG2 ANPEP ABHD6 GRN SPRY2 PDGFA CASP5 FABP5 CFD BST1 STX3 ATP6V1D TPP1 CTSD CDKN1A TM6SF1 MATK PRCP TMEM9B FLT1 CYB5R1 RAB31 HK3 CTSZ ATP6V0B CD83 IRF8 RALB PLCG2 ATP6V0D1 SORT1 FXYD6 MCUR1 CPT2 KYNU	down	***
GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP	0.0000000	0.0000001	0.7881868	-0.4045465	-2.133036	173	PAN3-AS1 OTUD1 CD44 BACH1 CIR1 YPEL5 NCF2 TET2 FRAT1 ZEB2 ATP2B1 ASAP1 UBL3 SERINC1 PICALM LITAF RGCC AKT3 ZFYVE16 SRGN TCF7L2 LINC00528 ZSWIM6 TCP11L2 PLAUR DAB2 THBS1 SOCS5 SCAF4 PDE3B PNRC1 CLK4 UBE2B DUSP1 IL7R PI4K2A BTG1 MED28 RABGAP1 IFNGR1 CSTA SKIL PNPLA8 DDX5 HOMER1 OGFRL1 TSPYL1 ZNF350 FOXO3 TGIF1 FAM228B BAZ2B MAP3K2 HBP1 APLP2 KYNU N4BP2L2 RGS2 CSNK2A2 CXCR4 EPHA4 NLRP3 PAIP2 THEMIS2 LYZ ARRDC2 CBX7 TMEM43 ZNF106 AOAH RB1CC1 ZFYVE1 ZFP36 SLC26A11 MTSS1 SNRPN RAB11FIP2 SIRT1 DUSP22 NR4A3 CFLAR MAT2B	down	***
GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP	0.0000000	0.0000000	0.7881868	-0.3989492	-2.132208	188	SIDT2 HMOX1 SWAP70 SOWAHC LPXN PPP4R1 GFOD1 YPEL5 SYS1 GGA2 EDEM1 ATP2B1 B3GNT5 ZBTB21 SLAIN2 NR4A1 NFE2L2 PPP1R13B ZEB1 BTG3 GMEB1 MAP2K3 ROCK2 CSRNP1 DUSP3 BIRC2 PXDC1 MAP1LC3B FBXL3 RBMS1 UBE2B CCSER2 DUSP1 PIK3C2A PLEK GNAQ PAFAH1B1 ANXA3 CD300LB VWF FOXN3 RYBP GABPA UHRF2 ATXN1L IFRD1 PNPLA8 MPZL3 CD83 HSPA13 PCGF5 RNF24 RHOQ CDK17 AZI2 ITGA9 RELL1 ATP6V0C MEIS1 WBP2 JUND C3orf38 IL18RAP LAT ITPRIPL2 ZNF438 MEX3C EPHA2 KPNA4 MAFK ARPC5 TLK2 PAIP2 NABP1 FCRL1 PUS3 TBPL1 TMEM43	down	***
GSE2706_UNSTIM_VS_2H_R848_DC_DN	0.0000000	0.0000002	0.7614608	-0.4063773	-2.130452	163	CXCL3 IL1A USP12 GREB1 ZC3H12C IL1B RAPGEF2 MIR22HG INSIG1 CCRL2 STX11 CLCF1 SGMS2 BTG2 MAP3K8 RNF144B TTYH2 ZNF697 SERPINB9 BTG3 MAP2K3 CSRNP1 PLAUR PXDC1 TNFSF15 DRAM1 DENND3 NFKB1 CXCL2 IRAK2 CCL4 ZBTB43 PLEK INHBA PIK3R5 TP53BP2 MAFF BTG1 NINJ1 SLC25A25 IL6 SOCS3 ARL5B STAT4 CELF1 PLK3 PPP1R15A PTGER4 IRF8 LYRM1 FSD1L REL ACSL1 FXYD6 EHD1 DUSP5 LRRC32 STK40 GEM ICAM1 TNFAIP8 MIR155HG TRAF1 NFKBIA EDN1 MCOLN2 NABP1 PMAIP1 PIM3	down	***
GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP	0.0000000	0.0000002	0.7614608	-0.4064033	-2.128245	157	USP12 LRRC8C MMRN1 SRSF7 INPP5A USP47 PDCL DNAJB14 ASAP1 MAP3K8 ZBTB21 ZNF410 ADIPOR1 ZEB1 SRGN BTG3 SDCBP DENND6A THBS1 MED6 SPAG9 PAFAH1B1 TP53BP2 USP16 FAM76B RABGGTB NINJ1 TECTA AREG DNAJC27 SGK1 SOCS3 SEC14L1 ARL5B MITF SH3BP5 CPEB4 SHOC2 IFNGR1 ELOVL7 PNPLA8 GPR183 KBTBD8 FSD1L REL UVRAG DLEU2 AGFG1 GPRIN3 CLUHP3 PELI1 PSMD12 VAV3 AP1G1 CCNH GEM INTS6 RAB5A ARIH1 TXNDC11 SSH2 OSER1 JMJD1C DNAJB9 MMD ZNF165 EHD4 PIM3 MB21D2 ICOS KMT2E C6orf62 PIAS2	down	***
GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN	0.0000000	0.0000000	0.8140358	0.4728003	2.125004	178	CDC45 BDH1 FANCI CCNB1 CENPF SORD BRCA1 PHGDH TTK GINS1 CDK4 AURKB PTTG1 GPI ESPL1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS UMPS MYBL2 SHMT2 NCAPD2 NME1 RUVBL2 MELK EXO1 NUDT1 MKI67 AP4M1 KIF3B EEF1E1 CCT5 AURKA POLD2 RRM2 RGL1 WDHD1 RAD54L PKM KIF11 MCM3 CDC25C ABCB6 AHCY RAD51AP1 ALDOA THOP1 TMEM106C EXOSC2 FEN1 EZH2 MRPS12 LAPTM4B TUBG1 DLGAP5 FAH PSMA5 SAP30 PSMB3 CDC20 AHCYL1 STAMBP MRPL28 MCM5 SLC1A5 LSM4 NEFH CCNA2 SERPINI2 TPGS2 PFKM SMC2 PAICS UBE2C ENO1 PPP2R5D CALU CYB5B RNF14	up	***
GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_DN	0.0000000	0.0000002	0.7614608	0.4792289	2.123418	157	FOXM1 HJURP TROAP XYLB PLEKHA5 MUC16 DEPDC1 BRCA1 GTSE1 DBF4B TRAIP DNMT3B PTTG1 E2F3 CCNB2 TYMS MYBL2 CCNF PLS1 SPPL2B HAUS5 WDR62 MELK EXO1 CLSPN RRM2 GCAT RAD54L ORC6 CC2D1A LRRC61 PKMYT1 PTGDR2 FADS2 TST NAA40 SLC25A10 HSPBP1 CDKN2C FASTK NUSAP1 ETV7 ASF1B CDK1 TNFRSF21 ATP2A1 E2F1 RECQL4 STK11 ZNF500 GSS PTGES2 TK1 PINLYP ATAD5 EPN1 KLHL23 CENPM AAAS TTLL3 CDK5RAP2 MRPL28 KPTN SLC1A5 NEFH SPON2 CEP85 MICAL3 RTEL1 DOHH CEP164 CAPN10 RHOT2 MXD3	up	***
GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP	0.0000000	0.0000001	0.7749390	-0.4037282	-2.119635	167	SC5D DENND5A GPR65 OTUD1 ARIH2OS YPEL5 AGTPBP1 HEG1 IER2 PDE2A ZBTB4 DPEP2 CNST PTPRM ASAH1 CLEC7A RNF125 PPP3CA SPTBN1 PDE4D TCF7L2 PPP3CC ITPRIP AHNAK PSTK KLF4 COQ10B KLF11 ST7L NR1D2 C9orf72 DUSP1 PLEK UBASH3B MAFF PKIG MYLIP SOCS3 UTRN AQP3 HCST SNX29 MAP4K4 ATXN1L SKIL PNPLA8 MBNL2 GPR183 FOS PTP4A1 BIN2 NAP1L5 FAM204A FAM228B TSC22D1 ZNF844 IRS2 PIM1 KCNA3 GABARAPL1 TOB1 HELZ EPHA4 TTC32 CD3G DNAJB9 ITCH ZFAND2A CFL2 MDS2 NR4A2 FAM8A1 DRAM2 ASH1L-AS1 MICAL1	down	***
GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP	0.0000000	0.0000001	0.7614608	-0.3986979	-2.117798	177	CD52 SIK1 HSD17B11 SAMHD1 CITED2 CRY2 YPEL5 MSRA DYRK1A ANAPC15 FRAT1 TMX4 CCNL1 TXNIP ANXA1 PPP3CA CLK1 PDE4D EVI2B MOAP1 ITM2B LEPROTL1 MED6 MGAT4A NPAS3 PER1 ALOX5AP CCDC59 EVI2A ARL4A MAPRE2 ARHGDIB BTG1 KLRB1 PIKFYVE AQP3 HECA CD48 JUN JUNB PIK3R1 MBNL2 ENTPD4 UVRAG TSPYL1 SNRK FOS KLF2 PTP4A1 YTHDF3 MYL12A TSPAN14 IRS2 HBP1 TOB1 KANSL2 CLEC2B HAUS3 BNIP3L SLC35D2 RLF EPHA4 S100A4 ICAM3 NR3C2 NUP160 CNN2 PPP1CB ARHGEF18 NR4A2 RB1CC1 FAM8A1 FAM53B CD69 DNAJB1 PIAS2	down	***
GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP	0.0000000	0.0000000	0.7881868	-0.3965542	-2.114734	182	SEMA6B EPAS1 ABHD5 OLR1 TAL1 LPXN THBD PID1 RCOR1 AATK PPP4R1 GFOD1 RTN3 INPP5A C5AR1 MSRA CD9 AGPAT4 USP47 PFDN1 PPM1D TRIB1 CASP9 AVPI1 HBEGF LMNA CHMP1B ANXA5 REV3L PDE4D TIPARP ZMIZ1 FOXO1 PAQR5 DAB2 SLC7A8 SSH1 PDE3B VIM IL7R MMP19 HGSNAT CLN8 PKIG SOCS3 HECA PHF10 LTBP2 MAP4K4 IFNGR1 GPR183 UNC13B APH1B	down	***
GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP	0.0000000	0.0000007	0.7337620	-0.4041068	-2.113961	158	SC5D MIR22HG HSD17B11 OTUD1 CITED2 BMPR2 YPEL5 PDCL TMX4 ANXA1 DPEP2 CNST DNAJC3 FBXO7 PTPRM UBL3 ASAH1 NAAA BTG2 RNF125 FBXL5 EVI2B ITPRIP ZNF423 SELL SNORA28 DUSP1 RNF139 PLEK GNAQ IL7R VCPKMT SNN KLRB1 SGK1 AQP3 ETV3 SNX29 MAP4K4 TYROBP JUNB FYTTD1 ATXN1L SKIL FOS KLF2 YPEL2 PTP4A1 TRAPPC10 BIN2 GSAP ZRANB1 ABHD13 IRS2 PIM1 KCNA3 KANSL2 MEGF6 PDE4B EPHA4 EPB41L4A LYZ DCUN1D2 CDC14A TNFSF8 NR4A2 FAM8A1 SLC26A11 CD69 DNAJB1 SPTY2D1 SNRPN MEF2D ITGA6 PTGS2 YOD1 NFKBIZ FBXO33 WHAMM	down	***
GSE2706_UNSTIM_VS_2H_LPS_DC_DN	0.0000000	0.0000002	0.7614608	-0.4031257	-2.113405	163	CXCL3 IL1A USP12 RAPGEF2 INSIG1 OTUD1 CCRL2 STX11 IL23A ADA BTG2 TNIP3 MAP3K8 RNF144B TTYH2 ZNF697 EPM2AIP1 BTG3 GMEB1 IL10 MAP2K3 CSRNP1 PTGIR PLAUR PXDC1 NFKB1 CDKN1A P2RY2 CXCL2 ATF3 IRAK2 INHBA PIK3R5 TP53BP2 BTG1 NINJ1 HCAR3 CD80 IL6 SAR1A SOCS3 OASL ETV3 ARL5B PTGER4 IRF8 GPR183 FAM43A REL ACSL1 PELI1 FXYD6 EHD1 DUSP5 LRRC32 SOD2 GATA6 GEM ICAM1 IL18RAP TNFAIP8 MIR155HG RIPK2 NUP98 TRAF1 NFKBIA EDN1 LDLR NABP1 PIM3 ZNF385B DCUN1D3 HES4 MSANTD3 LAMP3 SLC43A3 IRF1 NR4A3 CFLAR HIVEP1 NFKBIZ DUSP2 C15orf48	down	***
GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP	0.0000000	0.0000004	0.7477397	-0.4027548	-2.110834	159	SPN SNX10 TTC7B CD44 MYADM MEF2A IL1RL1 GNPTAB ZEB2 ANXA1 ATP2B1 CYP17A1 LATS2 ENTPD1 ZDHHC2 LITAF LAIR1 IL18R1 DUSP3 PPT1 AHNAK PLEKHM3 OSTF1 CLIC4 CTSD ITGAX HOPX ATP6V0D2 ID2 TEF PRF1 IL7R PIK3R5 CALM2 EMP3 MYLIP CD80 HCST NDNF CD48 CCDC50 EEA1 DAPK2 COBLL1 TBX21 GPRIN3 NKG7 KLRC2 PIK3AP1 SMPDL3B CHPT1 GSAP ATXN1 LGALS3 POLK IL18RAP ARHGAP18 HAVCR2 KLRK1 RORA CX3CR1 UBA6 ITGAL ITGB1 PIK3CG S1PR5 ATP2B4 RPA2 DOCK5 CD226 TTC39B RNF19B BMPR1A MYO1F MYO5A EMP1 TNFRSF1B F2RL2 GZMK SOS2	down	***
GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP	0.0000000	0.0000008	0.7337620	-0.4033655	-2.107397	154	CPEB2 SIK1 BAIAP2 PRAM1 VAMP2 CCNL1 SBDS BTG2 EIF5 NR4A1 ADRB2 HNRNPDL CLK1 MTHFR GPR4 CSRNP1 AGO3 KLF4 SPAG9 NR1D2 ATF3 CLK4 SMAD7 ELMSAN1 GCA MAFF SLC25A25 CREM SF3B1 ARL5B PLK3 UHRF2 DUSP8 SKIL DDX5 FRYL STX5 REL HOMER1 TNFRSF10B TINF2 SLC3A2 TGIF1 CDC37L1 TAGAP CRY1 TAGLN SERTAD1 TRAF1 RND1 KATNA1 FNBP4 PDE4A TTC19 ZFAND2A EIF4A2 HNRNPH1 YTHDC1 EGR1 NR4A2 GAS5 SLC38A2	down	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP	0.0000000	0.0000001	0.7749390	-0.3970069	-2.107176	178	SMAD6 CD52 SASH1 TSPAN4 DENND5A HHEX GATA2 GPR65 PTPRE RAMP2 HSD17B11 SH2D3C CD44 MYADM AQP9 MANBA CD9 TLCD2 ANXA1 LACTB HBEGF CD33 ASAH1 LUZP1 LITAF SIRPA SPI1 TUBB6 CST3 PTPN12 ST3GAL2 TJP1 TMBIM1 ITIH5 ITGAX PTGER3 PLEK KLRD1 MAPRE2 HCK PROCR PRCP RNF149 CABLES1 RAB31 KCTD12 TYROBP SELENBP1 OGFRL1 DYM TAGLN2 CD34 ACSL1 CD151 RHOQ RRAS IRF5 SERPINB1 TSC22D1 CD81 GABARAPL1 PLA2G15 CALHM2 S100A4 GLUL RORA THEMIS2 WDFY3 RNH1 CNN2	down	***
GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN	0.0000000	0.0000001	0.7881868	-0.3958502	-2.106669	184	CXCL3 ADTRP SOWAHC ZC3H12C LHCGR EGR2 CCRL2 BAG4 CITED2 CDC42EP2 IER2 CCNL1 BTG2 MAP3K8 KLF6 MCL1 TIPARP IL10 CSRNP1 TLE4 ACSL3 AOC3 ID3 ZFAND5 CXCL2 ATF3 ID2 CCL4 PNRC1 DUSP1 MAFF RASGEF1B PROCR NRROS RPS6KA2 SLC25A25 RYBP SGK1 SOCS3 ETV3 JUN ARL5B HSPA1B JUNB RCAN1 PPP1R15A PTGER4 SKIL IFRD1 OSM MALT1 ATL2 REL FOS PELI1 CDK17 MAPK8 ATPAF1 EHD1 TGIF1 TEX30 DUSP5 PIM1 GPR84 TOB1 PDE4B PHLPP2 SMAD2 C3orf38 CTTNBP2NL IER5 SETDB2 MEX3C GPD1L TRAF1 NFKBIA TLK2 TNFSF9 NABP1 ARFGAP3 DNAJA2 HERPUD1 EGR1 ATF2 CLEC4E OSGIN2 SLC38A2 ZFP36 YRDC DNAJB4 CD69 TRIM13 IRF1 CHKA CFLAR PTGS2 NFKBIZ DUSP2 RNF19B ST3GAL1 SLAMF7 IL10RA FEM1C	down	***
GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP	0.0000000	0.0000001	0.7614608	-0.3989612	-2.103587	173	EPAS1 PECAM1 PTPRE TUBB1 CCRL2 GFOD1 CBL TGFBR2 PDE2A PLA2G7 ABCG2 HLX ADIPOR1 TMEM123 AKT3 FLI1 SDCBP TCP11L2 ITM2B ROCK1 ZFAND5 STK17B THBS1 LAPTM5 PDE3B PTPRC SELL HPSE LBH ELMSAN1 ARL4A CPT1A KLRD1 ARHGDIB HEXB MYLIP CREBRF SLCO2B1 HCST HECA MSRB3 TYROBP RAB8A LPCAT2 AP3B1 RASSF2 RHOQ HIVEP2 WNT11 CD1D DCK BAZ2B GNB4 ANKRD13A JUND BMP2K SELPLG BNIP3L WDR1 CDC42EP3 TPT1 SSH2 ABI3 CD3G RNF38 HEBP1 CNN2 ARFGAP3 PPP1CB ARHGEF18 CNR2 LNPEP RB1CC1	down	***
GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_DN	0.0000000	0.0000001	0.7749390	-0.3980300	-2.102550	174	FFAR4 RBP4 SLC31A2 LPIN2 OLR1 DLC1 TMEM52B LTA4H SNX10 APIP SYS1 SLC7A7 ECHDC1 FAM89A ANXA5 ABCG1 KLF10 LAIR1 ZMYM6 IL18R1 GRN CD58 ZMIZ1 MOAP1 PPT1 LIMS1 SLC46A2 RNFT1 PLAUR GCHFR ID3 RMDN3 ID2 DUSP1 ELK3 SMAD7 ARL4A CLIP4 GPR157 HES1 BTG1 SLC8A1 GABARAPL2 SLCO2B1 TREM1 DNASE2 TMEM251 SKIL GRB2 GPRIN3 AZI2 BIN2 TFEB DOK3 TESK2 MAP3K2 GPR84 GNB4 ADPGK SLC43A2 MIR155HG CEP170 BLOC1S2 PSME4 SSH2 ISCU GLUL NFKBIA SKI RHOT1 GRB10	down	***
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP	0.0000000	0.0000001	0.7614608	0.4693064	2.102289	169	CCL19 KIF20A FANCI AP3B2 BUB1B CCNB1 TTK RACGAP1 E2F8 CDCA8 AURKB PTTG1 AKR1C1 ESPL1 TPX2 CCNB2 MCM2 TYMS COCH DTL ZWINT AGK MELK NDUFB8 HMMR KIF23 MKI67 CUL9 EMC9 KIF15 IGLV1-44 KIF2C ABCC5 RRM2 RGL1 RBM28 KIF11 CHEK1 FBL RAD51AP1 AKT2 WNT5B IDH2 MNAT1 NUSAP1 TMEM106C CBX5 CDK1 POLE2 BIRC5 NCAPG SLC25A13 FEN1 SPAG5 SNRNP25 DLGAP5 UROS TK1 DTYMK GINS2 GALNT3 CDC20 MCM6 TDP1 LANCL2 RHOBTB1 STK39 NEDD8 CCNA2 SLC2A5 STAB1 TTC31 CAPN10 SEC13 AGBL5 UQCRQ OSGEP BCAS3 CDC25B UBE2C MZF1 C12orf10 CCL13 PARP2	up	***
GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000000	0.0000000	0.8012156	0.4687959	2.101293	170	KIF20A MCM10 FANCI BUB1B IGF2BP3 TIMELESS UBE2T MPP6 CPSF6 KIF18B NDC80 PRIM2 GINS1 POLE STIL AURKB CENPA PTTG1 ECT2 RBBP8 XPNPEP1 NUDT1 CISD1 CEP55 SMAGP KNTC1 TOP2A CENPL MCM7 CENPW MMS22L FANCD2 MCM3 PFN2 LIG1 ORC6 MAD2L1 CKAP2L RAD51AP1 XRCC1 WNT5B NCAPG2 CDKN2C NUSAP1 ASF1B GMNN POLR3K NCAPG DNA2 CENPP TSNAXIP1 SNRPA HMGN3 ESCO2 GINS2 ASNS ATAD5 DNASE1 CENPK LIMA1 ASRGL1 ZRANB3 GINS3 HMCES GNAL PRR11 SNRPD2 BLVRB ZWILCH ARHGAP11A MXD3 VDAC3 SLC12A2 SMC2 PGPEP1 TMEM256	up	***
GSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_UP	0.0000000	0.0000003	0.7477397	-0.4006455	-2.099359	165	SLC31A2 CD300LF HMOX1 FABP4 LIPA ARL8B SLC15A3 FUCA1 LAMP1 ACER3 NCEH1 UBL3 CD33 ADAM17 HLX STOM NDEL1 APOC1 PDGFA RAB14 IL10 SDCBP DAB2 MAFG ID2 PLEKHB2 PRF1 PLEK UBASH3B ANXA3 LACC1 FMNL2 SNAP23 SLCO2B1 JUN SNX29 PLK3 EEA1 ATP6V0D1 TIMP2 CRYZL1 SBF2 CD86 PLEKHO2 SLC43A2 IL18 CGRRF1 CEP170 MS4A4A SAMSN1 TMCC3 THEMIS2 NRP2 DOCK4 EHD4 PHYH DUSP6 SPPL2A CAPZB TREM2 PTGS1 FXYD5 PDE7B SERP1 ATP8A1 FNDC3A SKAP2 CPNE2 PDPN CFLAR LRP1 SLC29A3	down	***
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_DN	0.0000000	0.0000000	0.8012156	0.4672378	2.098980	171	MDM1 HJURP MCM10 GMDS FANCI CHEK2 BUB1B GGCT PHF14 DEPDC1B TTK CDCA2 SLC27A2 ANLN CCDC14 ASPM WDR70 CCNB2 TYMS CDC25A MYL6B COQ3 HMMR DNPH1 EXO1 RPL39L KIF15 KNTC1 TOP2A AURKA VANGL1 TTLL12 PKM FANCD2 B3GNTL1 MAD2L1 CENPO BLM MNAT1 CCDC138 PSRC1 CKS1B CDKN2C ASF1B BCAS4 BIRC5 ATIC POC5 NCAPG TRAP1 TMEM79 SPAG5 SRD5A1 RNASEH2A CHCHD3 GNPAT PSME2 MGMT ANP32E PKP4 FUCA2 MAGOHB RNF187	up	***
GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP	0.0000000	0.0000001	0.7749390	0.4668847	2.095302	172	HELLS CDC45 NEK2 CENPF SLC9A2 BRCA1 DEPDC1B ECE2 CDCA2 E2F8 CDC6 E2F3 TYMS CDC25A UMPS MYBL2 ZWINT AGK LSM5 HAUS5 BZW2 NOP9 TOP2A AURKA EME1 SAE1 CLSPN RAD54L PKM GPSM2 MCM3 CDC25C L3HYPDH THYN1 CKAP2L PPP5C ALG3 GEMIN4 CDKN2C NUSAP1 ASF1B EXOSC2 CENPJ BIRC5 ATIC NCAPG CMTR1 DNA2 EZH2 MTBP NOP2 DGCR6 UBFD1 ILF2 MBD4 KIF20B TM9SF4 CHADL MAGOHB ATAD5 C16orf58 HAUS6 URB1 POLR3E STK39 ATAD2 DUS2 CCNA2 ABCF2 WDR4 SNX7 ZWILCH ARHGAP11A UHRF1BP1 TMEM101 NUBPL GMPR2 UBE2C ERRFI1 RAD1 NAT10 TMEM201 CALU NQO1 PARP2 PCGF6	up	***
GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP	0.0000000	0.0000002	0.7614608	-0.3952711	-2.093955	175	HMOX1 USP12 IL1B MIR22HG ENG BMPR2 CDC42 HEG1 LMNA BTG2 ANPEP SERPINB9 RBM4 SRSF2 CRK CLK1 PDGFA TIPARP RHOB MAP2K3 FABP5 HNRNPA3 LIMS1 PXDC1 THBS1 CCL3 NFKB1 CDKN1A RBMS1 CXCL2 ATF3 CCL4 DUSP1 TP53BP2 SRF EMP3 PRKRA CREM OASL SRSF3 SERPINB8 SH3BP5 RAB31 JUNB PPP1R15A DHX15 CD83 ATP13A3 YWHAZ RUNX3 TEX30 DUSP5 CD86 PIM1 PPP3R1 MACF1 GEM ICAM1 SP100 TRAF1 S100A4 BCAT1 SFPQ DNAJB5 SERPINE1 FUS S100A8 ZFP36 CD69 DNAJB1 LAMTOR5 TRIM25 MSC CD4 KRT10 DUSP2 RNF19B EMP1 IVNS1ABP PNP	down	***
GSE3982_MAC_VS_TH2_UP	0.0000000	0.0000001	0.7749390	-0.3959170	-2.091388	174	DNAH17 SWAP70 FCN1 TSPAN4 SLC47A1 USP12 WFDC1 FABP4 ENG FIG4 HSD17B11 EGR2 PLEKHF2 CCRL2 RASAL2 FUCA1 FRAT1 SLC11A1 DPEP2 MAN2B1 SLC7A7 ANPEP LAMTOR3 SPRY2 CCL22 LIN7C CPVL UBTD1 MVB12B MAP1LC3B SOCS5 SPAG9 CDKN1A P2RY2 PAPSS1 FRMD4A CAPZA2 CCSER2 INHBA SMNDC1 NRBF2 CLN8 TBC1D5 PRCP HCAR3 PDHX PSEN1 RHOBTB2 TREM1 ENPP4 SPATA2L MORF4L1 SLC25A24 AZI2 CD74 PPP2CB STXBP3 VAV3 GALC HBP1	down	***
GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP	0.0000000	0.0000001	0.7749390	-0.3920539	-2.086466	184	IL1A SOWAHC GLIPR2 IL1B SNX10 CAV1 MYADM CALCRL PLEKHA1 BCL2A1 IL1RN MOB1B IER2 TRA2B SLC7A7 SLC25A17 PPP1R15B MAP3K8 SRGN PDGFA RHOB IL10 MSR1 STAT5A RAB12 PLAUR VASP NFKB1 CDKN1A CXCL2 SELP C9orf72 CCND2 DSTN N4BP1 KPNA3 PROCR UFM1 PNO1 SOCS3 MTMR14 KCTD12 MAP4K4 HSPA1B JUNB WTAP IFRD1 DDX5 ACSL1 AGFG1 RHOQ PELI1 YTHDF3 PBRM1 EHD1 IFNAR1 PIM1 STK40 IST1 ICAM1 SLC31A1 SERTAD1 CEBPD HSP90AA1 TAB2 RBM18 HNRNPK MCOLN2 TNFSF9 NAA15 MT2A PPP1CB HNRNPH1 SERPINE1 SSB EFNB2 UBE2N KCMF1 TES DLD FNDC3A PDPN PTGS2 NFKBIZ DUSP2 RNF19B	down	***
GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000000	0.0000003	0.7477397	-0.3921435	-2.082982	177	CXCL16 DENND5A GPR65 RAPGEF2 YPEL5 STX11 USP47 HPS5 PDE2A EIF4A1 TNFRSF8 B3GNT5 SLC36A4 BZW1 MAP3K8 NFE2L2 TMEM41B PDE4D TFRC TIPARP DIABLO ZMIZ1 MAP2K3 CDADC1 PLAUR MAFG SNIP1 CDKN1A GGTLC1 C9orf72 PLEKHB2 DNTTIP2 OXSR1 N4BP1 PIK3R5 MAFF SEC31A TAF13 LACC1 EMP3 PPP2CA PSEN1 RAB8B ETV3 MAP4K4 WTAP PNPLA8 CD83 HSPA13 ATP13A3 HIVEP2 RBKS ZBTB1 DUSP5 CTNNAL1 PHF19 SOD2 THAP9 ZNF267 PDE4B RLF WDR1 IER5 METTL21A ARIH1 TXNDC11 NUP98 G3BP2 NFKBIA MAFK	down	***
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN	0.0000000	0.0000004	0.7477397	0.4748139	2.080994	140	TRIP13 SLC16A14 HP FOXM1 KIF20A HJURP CENPF FRK MND1 KIF18B DEPDC1B TTK GINS1 E2F8 KIF14 ANLN ASPM OTOGL CDCA8 TBX19 GAPDH BCL2L14 SLC7A9 TMEM132D DTL KIF27 MYL6B CLDN1 MELK HMMR CEP55 MKI67 KIF15 BUB1 AURKA METTL7B MYO10 SLC2A10 C1orf226 KIF2C CDCA5	up	***
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP	0.0000000	0.0000001	0.7614608	0.4663868	2.075445	161	STRC CEACAM1 TICRR BUB1B CENPF PBK CLGN NDC80 SRGAP3 TTK KIF14 ANLN ASPM NUF2 CDCA8 PTTG1 TPX2 TFDP2 CCNB2 RAD54B PRC1 CCNF HMMR CEP55 GFPT1 MKI67 KIF15 KNTC1 BUB1 TOP2A CLSPN RRM2 RAD54L KIF11 GPSM2 CDC25C CHEK1 CKAP2L NEB CCDC136 INCENP GPX8 CKS1B NCAPG2 PLOD2 CDK1 PPIC BIRC5 ADAP1 NCAPG NEIL3 OCIAD2 RTP4 HSPA4L TACC3 KIF22 CCDC146 LCLAT1	up	***
GSE14415_INDUCED_TREG_VS_TCONV_UP	0.0000000	0.0000003	0.7477397	0.4670679	2.071827	156	TRIP13 CEP72 CDC45 MCM10 TROAP POLQ PBK KIF18B PRIM2 PHGDH GINS1 TRAIP PLK1 NUF2 CDCA8 AURKB CCNB2 FIGNL1 SHMT2 SPDL1 NME1 RANBP1 HMMR NUDT1 MKI67 KIF15 BUB1 AURKA MCM7 RRM2 CDC25C MAD2L1 CKAP2L RAD51AP1 SPC24 DSCC1 PPIL1 CKS1B CDKN2C ASF1B CDK1 POLE2 BIRC5 GMNN ADAP1 POLR3K SLC25A13 PSAT1 NEIL3 SPAG5 ETFB CENPP PSMA5 SNRPA POLL KIF22 CHTF18	up	***
GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP	0.0000000	0.0000002	0.7614608	0.4663577	2.069885	158	TRIP13 DDX11 FOXM1 HJURP TROAP XYLB PLEKHA5 POLQ APOLD1 MUC16 DEPDC1 SORD GTSE1 DBF4B TRAIP DNMT3B ASPM ESPL1 TPX2 CCNB2 TYMS CDC25A MYBL2 CCNF SPPL2B HAUS5 WDR62 MELK EXO1 MKI67 FANCA KIF2C CLSPN RRM2 RAD54L ORC6 CC2D1A PKMYT1 PTGDR2 SNAPC4 FADS2 SLC25A10 HSPBP1 CDKN2C FASTK NUSAP1 ASF1B CDK1 CEP97 ATP2A1 RECQL4 SERHL2 NRGN DLGAP5 GSS PTGES2 TK1 LRRC20 ATAD5 PPME1 CENPM AAAS GBF1 MRPL28 KPTN CACNB3 CHRNA3 ETV6 SLC1A5 SPAG4 CEP85 MICAL3	up	***
GSE3982_MAC_VS_TH1_UP	0.0000000	0.0000002	0.7614608	-0.3899539	-2.069741	178	SIDT2 SASH1 HMOX1 SWAP70 FCN1 CD101 ACE PHACTR1 DENND5A USP12 ATXN3 SLC6A12 ENG HSD17B11 PLEKHF2 RASAL2 NTM P2RY13 EOGT TMX4 RGCC SPRY2 EVI2B AGO4 PXDC1 KLF9 DRAM1 CEBPA SOCS5 SPAG9 ITGAX TLR4 GCA N4BP2L1 GNAQ EFR3A CLN8 TMEM9B SNAP23 VAT1 SNX29 TMEM251 SDHD OGFRL1 PPM1F SLC25A24 FOXO3 VAV3 IFNAR1 GALC APLP2 PLEKHO2 SERINC3 BMP2K SESN1 CEP170 CALHM2 RTN1 CHMP3 CES3 UBE2D1 SCPEP1 COMMD8 TMX2 MMD KIF1B CREG1 RABGEF1 PHYH ARHGEF17 CTSH MAPK1 CLOCK KCNJ1 TUBA1A CCNT2	down	***
GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP	0.0000000	0.0000002	0.7614608	-0.3899289	-2.069608	178	WEE1 ARHGAP31 PNPLA6 ACE CLDND1 FYN PDE1B PPP4R1 FLVCR2 TGFBR3 RFTN1 GGA2 ZEB2 SH2B3 PTPRM ENTPD1 TNIP3 LUZP1 TTYH2 CAMTA1 STOM RB1 SRGN MAP2K3 KIF1C AHNAK THBS1 MIR24-2 EPS15 LYAR KLRD1 PPP2R5C SH2D2A CRIM1 CNOT6L PI4K2A GLB1 TSPAN18 MYO1C PHACTR2 IL2RB OASL SEC14L1 ATP6V0B RAPGEF1 MPZL3 GPR183 GTDC1 TBX21 TIGIT CCR4 SAV1 AKIRIN2 ATXN1 GABARAPL1 RGS2 RXRA SYT11 IL18RAP CALHM2 NLRP3 RBMS3 AIM2 IQGAP1 PIEZO1 SLFN11	down	***
GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_UP	0.0000000	0.0000001	0.7749390	0.4599653	2.067317	178	CEACAM1 KIF20A CDH17 CHEK2 C21orf58 GGCT TBRG4 CDCA2 SLC27A2 STIL PLK1 CCNB2 HOXB7 MCM2 CDC25A MYBL2 CCNF ANKRD36B COQ3 CDT1 DNAH14 RANBP1 NDUFB8 EXO1 KNTC1 EME1 TMEM177 POLA2 E2F2 POC1A C1RL ERAL1 CKAP2L SPC24 GLE1 COQ9 CKLF MRPL37 ULBP2 PSAT1 SAPCD2 SLC12A8 DIAPH3 LAPTM4B MYO19 IFI27L2 SNRPA COL9A2 COMMD7 TMEM237 KIF20B KLHL23 WDR34 MGME1 PPCDC ROMO1 HAX1 SUOX LSM4 RRP36 SUV39H2 LRP11 CISD3 CCDC167 FARSB TPGS2 ZWILCH COX5B ARHGAP11A PAXIP1 NDUFA8 IKZF4 SNUPN ARHGEF39 MTHFD1 BCAT2 E2F7 C4orf46 MLLT11 ZDHHC13 MRPL12 EIF2B1 COMTD1 FAM111B DCLRE1B WDR5 TMEM214 HINT2 LRP8 XRCC5 HNRNPAB DHPS TMEM14A PUSL1 SKA3 ITPA NDUFA9 HMBS	up	***
GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_DN	0.0000000	0.0000003	0.7477397	-0.3890937	-2.067126	179	RAB11FIP1 NLRC4 KMO OLR1 OSBPL11 SECISBP2L GAPT IL1B TMEM170B DNAJB14 PBX3 CSGALNACT2 ADIPOR1 C1orf162 PPP3CA MPHOSPH6 TCF7L2 FBXL5 HMGN1 EFCAB14 TAPT1 MTMR6 PRKD3 PLEKHM3 THBS1 TM6SF1 ZMPSTE24 PINK1 SLC6A6 CNOT6L NCOA1 HAUS1 GZF1 FLT1 CDC40 GABARAPL2 HECA C2CD2 DESI2 MED30 DDX17 CARD8 TMEM251 UBAC2 PTGER2 ATP13A3 TRAK2 ZCCHC9 ZBED5 GAS2L3 PKD2 ATG2B ZBTB1 MILR1 KYNU SERINC3 CCNH PCM1 CPQ CEP170 MEGF9 CUL3 PAIP2 CAMSAP2 SPATA5L1 SPOPL HAT1 SLC19A2 MAPK1 ITGB1 FBXW2 XPO7 UBE3A HMGB1 PAXBP1 KLHL9 SRP14 SDCCAG8 DOCK5	down	***
GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP	0.0000001	0.0000031	0.6901325	-0.3986714	-2.066774	148	SIRPB1 LPIN2 ABHD5 CD101 DLC1 ADTRP LPXN PTPRE PPP4R1 RASAL2 SLC39A8 S1PR1 KCNN3 IL1RN NFATC3 CD8A HBEGF ADAM17 CRTAM CD58 EVI2B IL10 CASP1 USP2 CCL3 SELL CCL4 WASF3 ELK3 EVI2A TP53BP2 RABGGTB CD8B RBPJ FLT1 JUN LRCH1 GSTO1 IFRD1 GPR183 LSM1 CXCL5 RHOQ BCAS2 TCF4 STRN TEX30 KHDRBS1	down	***
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP	0.0000000	0.0000001	0.7749390	0.4598224	2.065183	175	FOXM1 HELLS FANCI NUP107 NEK2 IGF2BP3 CIB2 PBK KIF18B TTF2 TSPYL5 STIL ECT2 CDC6 TFDP2 MCM4 CCT6A ZWINT STAG3 CHAF1A MKI67 TP53BP1 BUB1 CCT5 AURKA CBX3 WDHD1 CHAF1B SOX4 YEATS2 SALL2 TOPBP1 CHEK1 ORC6 MAD2L1 PSMD4 BLM PABPN1 HDGF ATIC AAGAB LARP1 FEN1 SSX2IP NF1 SF3B3 ETFB PA2G4 IFT52 CHCHD3 DPP3 ALDH7A1 ARHGAP32 SPAG1 CCDC51 ZNF282 ENPP2 GALNT7 MARCKSL1 CDC7 CDC20 CENPM POP7 ASRGL1 PEX5 MCM6 PRMT1 CKAP2	up	***
GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN	0.0000000	0.0000002	0.7614608	-0.3890313	-2.064844	178	ABHD5 TSPAN4 DENND5A SNX10 CLDND1 HSD17B11 CD44 CTSW SAMHD1 ST3GAL6 MYADM AQP9 BCL2A1 CD22 ABCB1 ANXA1 ASAH1 MAP3K8 PBX3 LITAF PRSS12 MS4A1 SERPINB9 GATA3 IL18R1 CRTAM CYP4V2 PPP3CC AHNAK CASP1 OSTF1 SOCS2 PLBD1 ITGAX ID2 CCL4 RECK PLEKHB2 PRF1 EVI2A DSTN N4BP1 PLCD1 MAPRE2 CD160 GABARAPL2 SLC35E4 LIMD1 KCTD12 GSTO1 STX7 EEA1 DAPK2 IRF8 SERPINB6 CST7 KRTCAP2 CHPT1 LGALS3 FCGRT DBNDD2 RNF138 IL18RAP SEMA4A CYB5R4 TRAF1 S100A4 PALD1 KLRK1 CHCHD7 MCOLN2 CCND3	down	***
GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_UP	0.0000000	0.0000002	0.7614608	-0.3887599	-2.063404	178	MIR22HG SIK1 EGR2 FCER1A BCL2A1 GIMAP6 TRIB1 IER2 CCNL1 CD5 RILP PPP1R15B SDE2 MAP3K8 RNF125 GATA3 NR4A1 FAM122A CES1 SRGN BTG3 FBXO8 EVI2B CSRNP1 ITPRIP CASKIN2 COQ10B ID3 STK17B PER2 NKIRAS1 ATF3 CCL4 PNRC1 PER1 DUSP1 SH2D2A MAFF SRF NRROS ETF1 VAMP3 SLC25A25 ETV3 ARL5B PLK3 JUNB RHOG PPP1R15A MALT1 FOS FOSB CCR4 TGIF1 CD6 DUSP5 MAGOH IST1 ELF5 GEM SELPLG SFT2D1 LRP12 TOB2 MEX3C TRAF1 ISCU GPR171 SAMSN1 NABP1 ATF4 EGR1 DUSP6 ATP11B NR4A2 ZFP36 YRDC CD69 DPF3 SGIP1 TRIM13 TSC22D2 RAB1A FASTKD5 NR4A3 NFKBIZ KBTBD2 DUSP2	down	***
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN	0.0000000	0.0000008	0.7195128	-0.3912209	-2.059039	169	CXCL3 EREG ASGR1 ADPRH GATA2 LY86 CORO1C ZCCHC2 ARL8B OTUD4 RBM7 HSPE1 PLA2G7 RRAGC MAP3K8 CAV2 SLC7A11 SERPINB9 PPP3CA ZFYVE16 TFRC MAP2K3 FAM49B SNIP1 CDS2 TLR4 ZBTB43 CD53 MARK3 NCOA1 MMP19 TDRD7 SAR1A CD48 NOTCH1 PPP1R15A GSTO1 DHX15 HSPA13 GRB2 ATP13A3 RNF24 CGGBP1 HIVEP2 FOXO3 ICAM2 PRKCG ITGA9 FPR2 CTNNAL1 SOD2 GABARAPL1 NPTN MFSD12 IL18RAP LRP12 NLRP3 SP100 HNRNPC C21orf91 DOCK4 EMC3 RNF13 SPHK1 SPSB1 C1QB CHIC2 ZFP36 MT1E IFIT5 CD69 WNT5A	down	***
GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP	0.0000000	0.0000001	0.7749390	0.4585673	2.058135	174	TRIP13 HS3ST1 RUVBL1 CDC45 NOXRED1 KIF18B TBRG4 BRCA1 DEPDC1B CDK4 IQGAP3 ASPM STIL ECT2 CCNB2 RBBP8 RAD54B TYMS SHMT2 NCAPD2 C2orf81 NME1 KIF23 MKI67 FANCA CCT5 CENPL KIF2C CENPW MRPL3 MRPL27 PASK MCM3 ZNHIT1 C7orf50 CBY1 CAD MNAT1 PSRC1 NUSAP1 ASF1B SLC39A11 POLE2 POLR3K DNA2 NEIL3 RECQL4 NPHP1 TUBG1 SNRPA LMNB2 GALNS DTYMK MYBBP1A GINS2 ANP32E AGPAT5 TSSK3 SGSM3 CNDP2 CDC20 CHCHD1 LRRC59 GPATCH4 BCL2L1 MCM5 NOC4L LANCL2 FFAR2 TSR1 NUP62 CCNA2 PRIM1 PRR11 SHCBP1 RFC5 HK2 RAD51 ARHGAP11A ZMYND19	up	***
GSE34515_CD16_POS_MONOCYTE_VS_DC_DN	0.0000000	0.0000005	0.7337620	-0.3868618	-2.054927	177	SIDT2 SASH1 PDLIM2 DENND5A CPEB2 THBD BMP2 LMO2 CCRL2 NEDD4L C5AR1 S1PR1 ANAPC15 FUCA1 TGFBR2 ZBTB4 MCTP1 MAP3K8 RNF144B KLF6 ADIPOR1 CD93 CLK1 CYP4V2 MCL1 AGO4 PPT1 TCP11L2 PLEKHM3 CD302 ARAP3 ALOX5AP N4BP2L1 IL7R FAM76B RASGEF1B NCKAP1L NINJ1 MYLIP RNF149 NOTCH1 IRF8 PSTPIP2 WDFY4 PLCG2 RRAS PIK3AP1 ZC3H12D RELL1 BRI3 NBEAL1 KANSL2 DBNDD2 BNIP3L CXCR4 ARHGAP18 FNIP2 FNBP1 HTRA2 ITGAL ZFYVE1 EYA3 CCNT2 PIK3CG GPR137B STX16 EP300 PAXBP1 ATP8A1	down	***
GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_UP	0.0000000	0.0000002	0.7614608	0.4581169	2.052862	167	STYK1 KIF20A C21orf58 PSPH CMTM1 PLK1 CCNF COQ3 WDR90 RANBP1 FBXO43 KNTC1 TMEM177 E2F2 POC1A C1RL GPSM2 CDC25C ZNHIT1 CENPO RAD51AP1 SPC24 CAD INPP4B CKLF INCENP MRPL37 E2F1 REEP6 SDR42E1 METTL3 SAPCD2 LAPTM4B FGFR1OP CHCHD2 NET1 SNRNP25 IFI27L2 TSPAN17 GSS SNRPA DHODH DTYMK C1orf131 ESCO2 GINS2 KIF20B ASNS FBXO44 TCEA2 VPS25 STOML2 WDR34 MGME1 PPCDC ROMO1 NOC4L GGT5 LSM4 CHRNA5 RRP36 FARSB AIFM2 PAXIP1 WDR76 SNUPN ARHGEF39 LIF CENPE BCAT2 E2F7 C4orf46 CALU MLLT11 EIF2D DRG1 MRPS16 ZDHHC13 MRPL12 DSN1 COMTD1 FAM111B	up	***
GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN	0.0000000	0.0000010	0.7195128	-0.3909454	-2.048532	165	CLIC3 PHACTR1 LYVE1 GPR65 PTPRB FYN RGS9 CTSW GFOD1 TGFBR3 ABCB1 CD8A GGA2 ZEB2 CACNA2D2 C1orf21 BZW1 MAP3K8 LITAF ADRB2 CRTAM PDGFA PTPN12 YBX3 MVB12B ITPK1 RIT1 ID2 CCL4 PRF1 PLEK KLRD1 MATK SH2D2A CRIM1 CD8B PKIG CD160 IL2RB GTDC1 HOMER1 TNFRSF9 TBX21 CASZ1 CST7 CDK14 PLCG2 RHOQ UBB RUNX3 NKG7 VAV3 TCF4 PDLIM1 CLCN6 SPARCL1 SEMA4A SPIB CD19 PDE4A KLRK1 ITCH FEZ1 SPHK1 KLRF1	down	***
GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_DN	0.0000000	0.0000003	0.7477397	-0.3859426	-2.048450	178	EREG OSBPL11 U2AF1 CYP27A1 LPXN CLDND1 EGR2 RTN3 SLC11A1 SH2B3 SPG21 PICALM REV3L LCP1 PPP3CA SETD3 CD37 CD58 RHOB ZMIZ1 CCL22 AHNAK HNRNPA3 RNFT1 ZFAND5 THBS1 COTL1 PAPSS1 TM6SF1 ALOX5AP HTT ZNF706 CALM2 ATP6V0B CARD8 IFNGR1 DYM CST7 SLC3A2 FOS ATP6V0D1 TFEB GSAP PEA15 KIAA0232 TGIF1 VAMP4 TMEM230 NAB1 GALC ADAM10 RXRA PITPNA SEC63 CXCR4 ITGAE IFFO1 MAP3K4 PDE4A RNH1 VPS13D HERPUD1 CHP1 USP4 C5AR2 SH3BGRL3 EIF3L SLC38A2 FPR1 PTGS1 CALR HMGN2 POLR2L SERP1 PCMT1 RCBTB2 WDR26 PLCB2 KRT10 TPST2 GPATCH2L EMP1 ZCCHC14 BICD2 CPPED1 PYCARD	down	***
GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN	0.0000000	0.0000008	0.7337620	0.4565275	2.047525	168	TRIP13 MDM1 CDC45 GPT2 BUB1B PDCD2L TTF2 PRIM2 ALDH1L1 DNMT3B TTC26 CEP70 TPX2 TFDP2 SLC4A4 PRC1 INTS1 MELK RPAP1 KNTC1 IGF2BP2 CARD10 KIF2C E2F2 CLSPN WDHD1 PYCR2 LIG1 ORC6 MAD2L1 CKAP2L BRIP1 BLM FADS2 KNSTRN EFCAB11 BIRC5 GNB1L C1orf112 GMNN VANGL2 L2HGDH CENPP FOCAD RAPGEF5 DGCR6 KCNH3 CCNE1 DCLRE1C ALDH7A1 NMRAL1 LMNB2 MNS1 ZNF239 EDARADD KIF20B TRIM32 CD27-AS1 C15orf41 CEP128 PLEKHB1 SASS6 PTER CCDC30 ARVCF MYO5C HIBADH BSN NFE2 HTRA3 PRIM1 PRR11 TTC12 SHCBP1	up	***
GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_DN	0.0000000	0.0000001	0.7749390	0.4556928	2.045233	174	CEP89 CDC45 MCM10 ELOVL6 NEK2 PSPH BRCA1 TTK RACGAP1 E2F8 ANLN CDCA8 AURKB ECT2 CDC6 SFXN1 CCNB2 UHRF1 MCM2 MYBL2 PRC1 ORC1 DTL CDT1 TAMM41 RANBP1 EXO1 NUDT1 CISD1 KIF23 TOP2A AURKA MCM7 RRM2 RGL1 CDCA5 PDCD5 MRPL27 KIF11 CDC25C RBP1 KDELR2 CHEK1 ORC6 MAD2L1 AHCY BLM CKS1B DRC1 NUSAP1 CBX5 ASF1B CDK1 BIRC5 POLR3K E2F1 SSX2IP DIAPH3 KIF22 ZNF239 SAP30 CENPK PSMB3 CDC20 MRPL41 CKAP2 ROMO1 SURF2 NFE2 MRPL51 AP2S1 RPS26 CCNA2 RFC5 HK2 RAD51 SEC13 PGAM1 UQCRQ CENPE	up	***
GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN	0.0000000	0.0000003	0.7477397	-0.3845734	-2.044664	180	SASH1 INSIG1 ENG COQ2 LPL CD44 AQP9 SLC39A8 NR3C1 BCL2A1 OTUD4 FAM49A IGSF6 PFDN1 RFTN1 ADA SLC7A7 PTX3 SERPINB9 LAIR1 TFEC EPM2AIP1 BTG3 TFRC ATP6V1H STAT5A TBC1D9 CASP1 PTAFR NFKB1 KCNMB1 CCL4 M6PR N4BP1 CRIM1 RABGGTB HCK ZNF330 KANK1 HCAR3 CD80 PDHX FLT1 SOCS3 NECAP1 CD48 STAT4 RAC2 IFNGR1 GRB2 ZBTB24 DENND4A NDUFV2 CDK14 RHOQ RIN2 ZNF175 DDX18 EHD1 SERPINB1 NAB1 UTP3 KYNU PDE4B IL18 TNFAIP8 NBN RIPK2 UBE2D1 MAP3K4 NFKBIA ADORA2A PTEN DMXL2 FNBP1 ZFYVE26	down	***
GSE15767_MED_VS_SCS_MAC_LN_UP	0.0000000	0.0000010	0.7195128	-0.3899932	-2.044596	171	ACP5 ACVRL1 SASH1 OSBPL11 TMEM150B PID1 LY86 LMO2 C5AR1 CLEC10A FXYD2 MEF2A GAS6 EPB41L3 FAM49A ZEB2 ERG SLC7A7 ASAH1 CLEC7A ANXA5 HLX LRP4 MSR1 AGO4 MTMR6 PTPRO THBS1 PLBD1 SELL TLR4 FCER1G DSE DSTN HLA-DQA1 CLN8 NCKAP1L NINJ1 PKIG MYO1C RAB31 INMT ATP6V0B IRF8 SELENBP1 HOMER1 RALB MORF4L1 FOS SIGLEC1 TREX1 CPA3 NIPA2 FPR2 CPQ B3GALNT1 HSP90AA1 DACT2 EPHA4 ALDH2 ARPC5 TMCC3 NRP2 DOCK4 CREG1 FCRL1 PHOSPHO1 CSF2RB CAPZB MYH10 NCF1 HLA-DRB1 MFSD1 FCGR3A SKAP2 STARD5 KLHL9 BFSP1 CTF1 CLVS1 FNIP1 DUSP22 LRP1 METRNL	down	***
GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP	0.0000001	0.0000015	0.7049757	-0.3900225	-2.044104	159	USP12 CD55 CPEB2 TTC7B RUNDC3B OTUD1 CD44 PDE1B NEDD4L TBXA2R S1PR1 CD9 ZBTB2 FAM49A PDE2A ATP2B1 CYP17A1 RAPGEF4 LATS2 C1orf21 ACOT2 FOXP1 NR4A1 SGTB ZSWIM6 KLF4 PDE8A SELL SMAD7 PIK3R5 CRIM1 S1PR4 DNAJC27 SOCS3 SH3BP5 ETS1 MAP4K4 JAK1 CCR7 PIK3R1 FRYL GPR183 COBLL1 CD7 KLF2 MBP BIN2 C19orf38 SMPDL3B VAV3 PDLIM1 GNA13 RXRA AMD1 RNF138 IQSEC1 CXCR4 MEX3C GPD1L SSH2 KIF1B CCND3 ZBTB40 ARHGEF18 TNFSF8 CNR2 ATP11B CX3CR1	down	***
GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN	0.0000000	0.0000002	0.7477397	0.4574695	2.040435	162	TRIP13 FOXM1 PARPBP GPT2 BUB1B CCNB1 CENPF PBK CCDC113 TTK GINS1 E2F8 KIF14 NUF2 PTTG1 CDC6 TPX2 CCNB2 SPATS2 MCM2 TYMS GLDC DTL ZWINT MYL6B CLPTM1L MELK HMMR CEP55 SDHA MKI67 EMC9 KIF15 BUB1 AURKA IGLV1-44 RRM2 KIF11 IGKV1-5 CHEK1 ANKRD16 NUSAP1 CDK1 DMGDH NCAPG SPAG5 TUBG1 DLGAP5 IGHM FKBP14 CEP128 DENND5B CDC20 EFHC1 CLINT1 CREB3L2 NT5DC2 SLC2A5 DCPS SHCBP1 CCDC167 SMC2 MTHFD1 IGLV3-19 SRPRB CBWD1 ZC3HAV1L BFSP2 CD38 RTN4IP1 C11orf80 MRPL12 DSN1 FBXO5	up	***
GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN	0.0000000	0.0000001	0.7749390	0.4528484	2.039346	182	TRIP13 FOXM1 KIF20A RUVBL1 CDC45 MCM10 FANCI CCNB1 PBK DDIT4 TSFM DEPDC1 PHGDH CDK4 RACGAP1 ASPM AURKB PTTG1 ALDH18A1 ESPL1 CDC6 CCNB2 RBBP8 SMPDL3A SPATS2 XPNPEP1 ORC1 DTL NCAPD2 SPDL1 NME1 MELK KIF23 PAQR4 MKI67 KIF15 LGMN CCT5 MCM7 RAD54L KIF11 AIMP2 MAD2L1 RAD51AP1 DCTPP1 IPO9 NCAPG2 CBX5 MCTP2 RFWD3 NCAPG FEN1 EZH2 SPAG5 FGFR1OP ITPR3 DNMT1 DPP3 TUBG1 DLGAP5 TACC3 TUBB2A GINS2 ANP32E CLTA POLD1 CDC20 HMGA1 ZNF160 LANCL2 SRSF1 HMCES LRRK1 NT5DC2 AP2S1 RER1 SMARCA4 BANF1 SHCBP1 LPIN1 ATOX1 RARRES1 PGAM1 TNS3 SMC2 CENPE SEPHS1 PPIA UBE2C ADCK2 PLIN3	up	***
GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN	0.0000000	0.0000003	0.7477397	-0.3829525	-2.036046	180	CXCL3 MS4A7 KLF13 ZC3H12C FABP4 GREM2 CITED2 SLC15A3 IL1RN CBL CD22 FAM49A PLA2G7 NFIX ADAM17 PLXNA2 ANXA5 KLF6 TFRC CWC22 FABP5 CASP1 ITM2B AIRN ZFAND5 DRAM1 KLF7 ATF3 HPSE PLEK N4BP1 RUFY3 HGSNAT LACC1 NINJ1 RBPJ FMNL2 DDHD1 CYB5R1 SERPINB8 SNX29 USO1 CTSZ PTGER4 SNX2 PSTPIP2 HNRNPD AZIN1 SAV1 EHD1 ITGA9 FPR2 MCUR1 NAB1 IFNAR1 C16orf72 GPR84 SOD2 BRI3 STK40 ETS2 RNF2 ICAM1 NLRP3 TRAF1 PLGRKT NFKBIA MCOLN2	down	***
GSE3982_DC_VS_BCELL_UP	0.0000000	0.0000006	0.7337620	-0.3835778	-2.035647	176	GPD1 SLC31A2 TAL1 FBP1 LRRFIP1 CCRL2 SAMHD1 FOSL1 CLEC10A ALAS1 TGFBR3 CD1C FUCA1 LAMP1 PILRA CD36 ANXA1 ARHGAP10 ARSB ABHD6 RGCC TNS1 SPRY2 SLC19A1 CRTAM ATP6V1H SETD3 PDGFA TUBB6 ARRB1 BST1 STX3 SOCS2 TPP1 CDKN1A ATF3 CDS2 PAPSS1 ZBTB43 TM6SF1 MMP19 CLN8 SCEL PHACTR2 RAB8B MITF RAB31 HK3 TYROBP RCAN1 PODXL CD83 LSM1 AGPS SORT1 PEA15 CTNNAL1 MCUR1 CD86 RXRA SLC31A1 MS4A4A NLRP3 ALDH2 SLC2A9 ULK2 DAPK1 CD1E PDE4A	down	***
GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP	0.0000000	0.0000005	0.7337620	-0.3853242	-2.031113	172	GPR65 ARRDC4 EGR2 FGF10 GIMAP6 TRIB1 IER2 CD5 SBDS TM2D3 PPP1R15B MAP3K8 ADIPOR1 NR4A1 ADRB2 TMEM41B CLK1 SRGN TFRC FBXO8 ITPRIP ADO AOC3 COQ10B UBTD1 STK17B ADAMTS9 CCL4 CD302 PNRC1 PER1 DUSP1 ELMSAN1 MAFF SRF ETF1 VAMP3 LRRTM2 KIF13A PHACTR2 ETV3 ARL5B PLK3 JUNB DNAJA1 PPP1R15A PTGER4 GPR183 PTGER2 GRASP PREX2 FOS FOSB TGIF1 TSC22D1 DUSP5 KYNU ADAMTS15 EMC4 GEM MGAT2 SEC63 TOB2 RBM18 TTC19 GTPBP8 GPR171 NABP1 MS4A2 PIM3 EGR1 FKBP1B PNLDC1 ZFP36 CD69 DNAJB1	down	***
GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000000	0.0000003	0.7477397	-0.3804407	-2.028804	182	SMAD6 SEMA6A KMO SC5D SLC47A1 PECAM1 PPARG DCSTAMP CAT RDX THBD CCRL2 CCDC88A CYB5R3 SLC15A3 ALAS1 FUCA1 IGSF6 CD36 MAN2B1 HBEGF CD33 ANPEP ADIPOR1 ABHD6 TNS1 SLC19A1 ATP6V1H RAB14 CST3 CFD ZCCHC24 TPP1 CDKN1A ATF3 TM6SF1 CLIP4 HCK CLN8 PRCP VAMP3 C2CD2 MITF TYROBP PABPC4 CD83 APH1B PSMD12 RIN2 TIMP2 TCF4 PEA15 CTNNAL1 MCUR1 MEIS3P1 LGALS3 KYNU CCNH RXRA CPQ FKBP1A NLRP3 SCPEP1 DAPK1 BCAT1 CTSC CD1E ANXA11 EHD4	down	***
GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN	0.0000002	0.0000040	0.6901325	-0.3875727	-2.027467	158	CLEC1B IL17RB USP12 KLF13 DYRK1A TGFBR3 SYS1 IGSF6 TMX4 TXNIP LATS2 ENTPD1 RNF125 GATA3 PPP3CA TMEM123 TRAF6 PPP1R13B SRGN SPI1 ZYG11B AHNAK ZSWIM6 COQ10B KLF7 PLBD1 ID2 ARHGAP9 RNF139 CLEC9A PIK3R5 TANC1 GABARAPL2 DCTN6 TYROBP CCR7 PNPLA8 RC3H1 LPCAT2 ZNRF3 WDR7 WDFY4 CELF2 XYLT1 ZFAND6 DCAF5 DUSP5 MIA3 C16orf72 TOB1 TSPO RNF138 IER5 MAFK RORA THEMIS2 IQGAP1 RNF13 FEZ2 FNBP1	down	***
GSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP	0.0000001	0.0000016	0.7049757	-0.3864190	-2.024813	165	CXCL3 DENND5A CCM2L IL1B INSIG1 AQP9 ZCCHC2 SLC39A8 CD22 TNFRSF8 ATP2B1 SLC7A7 TNIP3 MAP3K8 RNF144B PTX3 LCP1 ARHGEF2 TCF7L2 CASP5 ZMIZ1 STAT5A SGTB LIMS1 ST3GAL2 THBS1 FMNL3 CXCL2 PNRC1 DSE SLC6A6 PIAS1 BTG1 IL6 NSMAF SOCS3 MAML2 OASL ZNF835 CD48 CELF1 MAP4K4 RCAN1 PTGER4 SKIL HSPA13 OSM ATP13A3 RASSF2 FPR2 IRS2 SOD2 RGS2 CCL20 CEBPD TAB2 TMEM184B PCBP1-AS1 HNRNPC TNFSF9 SAMSN1 CNN2 LINC00884 AFTPH VPS13D ADAM33 PRKCH S100A8 FPR1 MSANTD3 EBF1	down	***
GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_DN	0.0000000	0.0000005	0.7337620	-0.3812990	-2.023804	178	SMAD6 CXCL3 IL1A HMOX1 CPEB2 IL1B F2RL3 EGR2 GTF2E2 GPCPD1 IL1RN MOB1B IER2 SPG21 TRA2B SLC25A17 BTG2 MAP3K8 NR4A1 NDEL1 TMEM41B SRGN SOX7 BTG3 ATP6V1H PDGFA IL10 RAB12 LIN7C PLAUR SOCS2 FAM49B CDKN1A CXCL2 SELP CCND2 DUSP1 DSTN PLAC9 COPS4 PROCR ETF1 SGK1 SOCS3 KCTD12 JUNB DNAJA1 RCAN1 PPP1R15A IFRD1 EEA1 CD83 DDX5 FOS PELI1 EHD1 CD86 PIM1 TMEM70 STK40 ETS2 IST1 ICAM1 HSP90AA1 RBM18 NFKBIA TIMP3 MCOLN2 TNFSF9 MT2A YTHDC1 EGR1 SERPINE1	down	***
GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP	0.0000000	0.0000005	0.7337620	-0.3785622	-2.018786	182	IL1A SWAP70 SOWAHC EGR2 CD44 VAMP2 YPEL5 ZBTB2 CCNL1 ADAM17 ANXA5 ZBTB21 KLF6 PTX3 FOXJ3 NR4A1 MED26 NFE2L2 HNRNPDL LAMTOR3 PPP1R13B ZEB1 BTG3 UBE2D3 CSRNP1 MOAP1 DUSP3 COQ10B CDIP1 KLF7 ATF3 DUSP11 JAM2 UBE2B DUSP1 RPF1 PIK3R5 MAFF ANXA3 ZNF330 ETF1 MAP4K4 HSPA1B SHOC2 TBC1D12 PPP1R15A GLIPR1 THUMPD1 ZNF597 RNF24 ADNP2 IRS2 WBP2 GNA13 ETS2 ICAM1 C3orf38 ABL2 SERTAD1 IER5 RTN4 THAP6 MEX3C EPHA2 RASSF8 MAFK MRPL32 GNMT TLK2 PAIP2 SMAD4 PIM3 YTHDC1 CFL2 TMEM43	down	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP	0.0000000	0.0000008	0.7337620	-0.3863375	-2.015809	168	RAPGEF2 MIR22HG SAMHD1 BMPR2 PLEKHA1 TRIB1 HEG1 TOE1 ANXA1 DPEP2 CNST ASAH1 NAAA CLEC7A TRAF6 TCF7L2 ITPRIP AHNAK PSTK CASP1 KLF4 COQ10B NR1D2 SNORA28 DUSP1 RNF139 PLEK IL7R UBASH3B PIK3R5 MAFF NCOA1 SNN SLC25A33 TMEM9B SGK1 SOCS3 JUN MAP4K4 TYROBP JUNB RAPGEF1 FYTTD1 SKIL CD83 KLF2 PTP4A1 TRAPPC10 NAP1L5 VAV3 GSAP CHRAC1 ABHD13 TSC22D1 IRS2 PIM1 TOB1 RGS2 KTI12 INO80 USPL1 EPHA4 POLR2M SOAT1 EPB41L4A MTUS1 ZFAND2A SETX EXOG CDC14A TNFSF8 NR4A2 S100A8 SLC26A11 YRDC CD69 MFSD1	down	***
GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP	0.0000000	0.0000007	0.7337620	-0.3823209	-2.015282	172	ARHGAP31 GAPT ENG PLEKHF2 QKI MYD88 CDC42EP2 STX11 EPB41L3 TGFBR2 FAM49A IL23A ADA MTF1 TNIP3 MAP3K8 RNF144B LAIR1 SIRPA TMEM123 NFE2L2 EPM2AIP1 STAT5A ARRB1 PTAFR VASP STK17B THBS1 KLF7 CLIC4 TLR4 PNRC1 CCSER2 N4BP1 PIK3R5 CMTM6 LACC1 HCAR3 SYNPO2 PSEN1 OASL DNAJA1 RHOG ACKR3 PSTPIP2 GRB2 RBM22 TNFRSF9 TNFRSF10B ACSL1 RIN2 PIK3AP1 EHD1 SERPINB1 FPR2 KCNA3 PDE4B IER5 TAB2 NLRP3 RND1 MCOLN2 SAMSN1 CNN2 FNBP1 FJX1 CLEC4E DCUN1D3 EYA3 SRSF11 FPR3 UBE2W SERP1 IRF1 ADH1B CSF3 FAM89B NFKBIZ EBI3 RNF19B	down	***
GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN	0.0000000	0.0000006	0.7337620	-0.3790061	-2.015064	180	CXCL3 EREG KMO TSPAN4 DENND5A IL1B ADCY9 CDH5 FYN CITED2 BCL2A1 FAM49A OLFML2A MTF1 MAP3K8 RNASE1 PTX3 IL18R1 CRK ARHGEF2 MAP2K3 STAT5A CPVL SLC7A8 THBS1 CXCL2 DNTTIP2 IL7R TP53BP2 MARK3 BTG1 RPS6KA2 SERTAD2 KANK1 TECR IL6 BCAR3 UTRN MITF CTSZ MAP4K4 WTAP PTGER4 IRF8 GYPC AGFG1 PTP4A1 YTHDF3 SRSF6 RIN2 TIMP2 EHD1 UTP3 CCL20 GEM ICAM1 ANKLE2 CPQ WDR1 CDC42EP3 VPS4B NLRP3 TRAF1 DAPK1 BCAT1 ADORA2A	down	***
GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN	0.0000000	0.0000005	0.7337620	-0.3777164	-2.014276	182	HMOX1 IL1B MIR22HG INSIG1 FYN TRIB1 LMNA BTG2 KLF6 RNASE1 PTX3 HLX SLC7A11 LAIR1 RBM4 SRSF2 MAP2K3 SLC7A8 VASP THBS1 CCL3 NFKB1 CDKN1A RBMS1 CCL4 IL7R TP53BP2 SNN EMP3 RPS6KA2 SERTAD2 KANK1 TECR CREM OASL SERPINB8 SH3BP5 CTSZ MAP4K4 PPP1R15A WTAP PTGER4 FERMT2 IRF8 TCP1 TNFRSF9 YWHAZ DENND4A CLN3 SLC3A2 ATP6V0D1 PTP4A1 HIVEP2 TIMP2 TEX30 DUSP5 PIM1 APLP2 CCR1 GEM ICAM1 ABL2 CPQ CGRRF1 TRAF1 S100A4 BCAT1 DOCK10 PMAIP1 SERPINE1 TNFSF8 FUS ABHD14A DNAJC8 MTSS1 MAN1A1 IRF1 ATP8A1 TRIM25 MSC KRT10 DUSP2 RNF19B EMP1 PNP ADAM19 TNFRSF1B ZFHX3 EIF4A3 EZR C15orf39 CD47 PRPF4 APBB3 VNN2 TGFBI STX2 IFIT3 IFIT2 TUBB4B TNFAIP2 RGS16 ELL2 PHLDB1 PMP22 P2RX7 FCGR2A UAP1 RGS1	down	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP	0.0000001	0.0000028	0.7049757	-0.3843341	-2.012673	157	SC5D PGC GPR65 SIK1 HSD17B11 OTUD1 SAMHD1 CITED2 ELF2 YPEL5 AGTPBP1 BTG2 SPTBN1 PDE4D TCF7L2 ITPRIP AHNAK SGTB KLF4 COQ10B DENND3 KLF7 C9orf72 DUSP1 RNF139 UBASH3B MYH11 PIK3R5 MAFF C16orf54 PKIG MYLIP SGK1 SOCS3 SNX29 MAP4K4 JUNB ATXN1L SKIL PNPLA8 FOS YPEL2 BIN2 ADPRM FAM228B TSC22D1 IRS2 RELL1 KCNA3 TOB1 RGS2 KAT2B HAUS3 BNIP3L CCDC69 EPHA4 BRWD1 TTC32 OSER1 ING2 SIN3A DNAJB9 ITCH ZFAND2A	down	***
GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN	0.0000000	0.0000008	0.7195128	-0.3856382	-2.012160	168	DENND5A PECAM1 SECISBP2L RAPGEF2 PTPRE ENG MMRN1 LMO2 ST3GAL6 NR3C1 CD9 SCARF1 ERG EDEM1 UBL3 ADA EIF1 ITGA5 KLF10 GLS HLX FOXJ3 AKT3 ZFYVE16 PPP3CC ZMIZ1 PTPN12 STAT5A SRSF5 YBX3 ROCK1 SOCS2 KLF7 NPAS3 CDS2 CTBS RECK CCND2 WFS1 GNAQ AFF1 CRIM1 S1PR4 RYBP AK1 SERPINB6 CD34 ACSL1 FOXO3 TTBK2 MME BAZ2B N4BP2L2 PDE4B SEC63 CALCOCO2 BRWD1 TMEM87A THEMIS2 WDFY3 BMI1 DMXL2	down	***
GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000000	0.0000011	0.7195128	-0.3781211	-2.008832	179	MGAT3 ABHD5 PECAM1 CD55 FBP1 LMO2 CCDC88A P2RY13 FUCA1 WBP4 RHOA SH2B3 NDUFAF1 CD33 SERINC1 PBX3 CAV2 ADIPOR1 SPTBN1 CLK1 ZFYVE16 ATP6V1B2 ROCK2 TLE4 SDCBP FAM124B OSTF1 DENND3 SOCS5 CXCL2 TM6SF1 ALOX5AP CCDC59 TM9SF2 NRBF2 LMBRD1 ZCWPW1 VAMP3 FRY WASF2 PHTF2 ADAMTSL2 CRNKL1 PIKFYVE JAK1 PSTPIP2 TINF2 NDUFV2 PSMD12 BTBD7 CHPT1 SRSF4 MILR1 PIK3C3 PIM1 HBP1 PLAA SERINC3 ARPC2 LMOD1 LRP12 CYB5R4 OSER1 MARC1 NFU1 ANXA11 C21orf91 CREG1 EID1	down	***
GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP	0.0000000	0.0000005	0.7337620	0.4468646	2.008436	178	KLC3 CDC45 TICRR BUB1B NEK2 MND1 NDC80 PIF1 DEPDC1B ANLN STIL MSTO1 PLK1 CDC6 TPX2 RBBP8 SPATS2 RAD54B PRC1 DTL NCAPD2 DCTN2 TNC MELK EXO1 AURKA REC8 RAB19 POC1A RAD54L ANKRD13B KIF11 FANCD2 CHAF1B BRI3BP CHEK1 MAD2L1 AHCY RAD51AP1 SPC24 PERP BRIP1 PML RNF216 NCAPG2 C12orf75 ASF1B CDK1 STON2 CENPH ARPC1A DNA2 SAPCD2 UQCC2 DIAPH3 FGFR1OP TACC3 TK1 ADAR ANP32E LIN37 FHL2 NFE2 RNASET2 SUOX MARCKS ALMS1 CCNA2 SHCBP1 HK2 FARSB PFKM ARHGAP11A MXD3 DTNBP1 PAICS NDUFB7 COX6B1 C4orf46 CYP11A1	up	***
GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_UP	0.0000001	0.0000019	0.7049757	0.4486175	2.007447	166	FOXM1 HJURP CEP89 NEK2 CENPF PRIM2 BRCA1 RACGAP1 IQGAP3 E2F8 TRAIP POLE ASPM STIL IFT27 CDCA8 PTTG1 ESPL1 CCNB2 RBBP8 NCAPD2 TAMM41 WDR62 KIF23 MKI67 CENPL HHAT SNCG MCM7 E2F2 POC1A KCNV2 CHAF1B TOPBP1 MAD2L1 CKAP2L PIH1D1 MRPS11 PKMYT1 GLE1 PSRC1 CKS1B NCAPG2 NUSAP1 CDK1 KCNE3 CENPH BIRC5 E2F1 SPAG5 CENPP CAPS2 TACC3 KIF22 TUBA8 CHTF18 CENPQ GINS2 CEP128 CENPV CENPM ABCA7 MCM5 HEATR1 HAUS6 HAUS4 TC2N PRR11 RTEL1 RFC5 ARHGAP11A NDUFS8 CDC25B UBE2C GPN1 NUP210 DDB2 KIF24 PTPN13 TEX9	up	***
GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_DN	0.0000000	0.0000010	0.7195128	-0.3782248	-2.007239	176	CLIC3 PECAM1 CTSW TGFBR3 RFTN1 ABCB1 CD8A ZEB2 PTS CACNA2D2 C1orf21 BZW1 MAP3K8 LITAF KLF10 PPP3CA ADRB2 CRTAM TIPARP MAP2K3 FABP5 YBX3 MVB12B FAM49B ITPK1 HOPX ID2 CCL4 PRF1 SMAD7 PLEK ADIPOR2 KLRD1 MATK SH2D2A MAFF CRIM1 PROCR CD8B SAR1A CD160 IL2RB IDS LSM1 GTDC1 HOMER1 TBX21 CST7 UBB MFSD10 RUNX3 NKG7 JMJD6 GATA6 SYT11 PIP4K2A PTCH1 KLRK1 LYST MT2A IQGAP1 KLRF1 CHP1 CX3CR1 AOAH ITGAL MT1E CALR	down	***
GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000003	0.0000064	0.6749629	-0.3833925	-2.005600	158	ACVRL1 CPEB2 CDH5 HCAR2 CALCRL YPEL5 FAM49A ZEB2 UBL3 CD33 CYB5A MAP3K8 PICALM MS4A14 ITSN2 PPP3CC ARRB1 AHNAK PLAUR PXDC1 ZADH2 CEBPA FMNL3 UBE2E2 HPSE FRMD4A N4BP2L1 HES1 USP25 SCEL PSEN1 SOCS3 IL2RB UTRN SERPINB8 RAB31 KCTD12 PDE5A RHOG ENPP4 EGLN2 PXK NDST1 NKG7 RIN2 FCGRT KYNU IL18 PIP4K2A ORMDL1 SP100 S100A4 THEMIS2 GIMAP4 SMAD4 RNF13 EHD3 FCRL1 ABI1 CTSH ICOS RNF167 MICAL1 SGIP1 NMI STARD5 SLC25A45	down	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP	0.0000001	0.0000020	0.7049757	-0.3829235	-2.004929	160	SC5D MCOLN1 SECISBP2L MIR22HG SIK1 OTUD1 INPP5A HEG1 IER2 DPEP2 CNST DNAJC3 BMP1 PTPRM UBL3 NAAA CLEC7A TIPARP EVI2B ITPRIP AHNAK PSTK KLF4 KLF11 C9orf72 DUSP1 RNF139 PLEK IL7R MYH11 MAFF VCPKMT SNN HCK MYLIP KLRB1 SGK1 SOCS3 JUN SNX29 MAP4K4 TYROBP ATXN1L SKIL KLF2 PTP4A1 TRAPPC10 FAM204A VAV3 GSAP ZRANB1 FAM228B TSC22D1 IRS2 PIM1 KCNA3 TOB1 RIMKLB MEGF6 KAT2B EPHA4 TTC28 EPB41L4A DNAJB9 ZFAND2A LYZ GREM1 TNFSF8 MDS2 NR4A2 FAM8A1 MUL1 DNAJB1 SPTY2D1	down	***
GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN	0.0000004	0.0000080	0.6749629	-0.3832579	-2.002344	154	USP12 RASAL2 PRAM1 INPP5A CTDSP1 GAS6 ARHGAP29 ANXA1 WWC2 MAN2B1 LIFR LATS2 EIF1 CLEC14A CYYR1 HSPB1 JAM3 TNS1 CD93 CRK CDADC1 UBTD1 FMO2 ID3 THBS1 ADAMTS9 MYO1B ATF3 DSE TDRD7 TOPORS PDK4 MYLIP PRKRA SLC25A25 SGK1 MAGI2 PDE5A ARHGEF10 GPR141 RCAN1 KLRC2 C19orf38 DUSP5 GNAI1 LRRC32 TOB1 NBEAL1 PGGT1B TAGLN IL18 ORMDL1 ULK2 KLRK1 CECR2 NDUFAF5 FEZ2 KALRN DUSP6 RB1CC1 GNG11 AKAP12 ATP8A1 TNFSF18	down	***
GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	0.0000000	0.0000011	0.7195128	-0.3784385	-1.995378	173	SC5D ABHD5 RAPGEF2 INPP5K S1PR1 ANXA1 ASAH1 BTG2 MAP3K8 SRSF2 TCF7L2 CSRNP1 MTMR6 MOAP1 ITPRIP FOXO1 PSTK COQ10B LEPROTL1 DUSP11 CD302 DNTTIP2 UBASH3B PIK3R5 MIR17HG IKZF5 TMEM9B CCNY DDX20 NXF1 HECA ETV3 NOTCH1 PTGER4 PIK3R1 TPP2 OGFRL1 ZNF350 ADNP2 PELI1 SRSF6 TRAPPC10 NAP1L5 AZIN1 VAV3 TCF4 SMCR8 ADPGK KTI12 GTF2B IQSEC1 CXCR4 USPL1 TXNDC11 TMEM184B SOAT1 NFKBIA JMJD1C RNF38 TTC19 ZNF791 DNAJB9	down	***
GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN	0.0000000	0.0000012	0.7195128	-0.3824009	-1.995269	168	CXCL3 KMO CD55 HHEX MKNK1 ZEB2 UBL3 ASAH1 SERINC1 MAP3K8 ABCG1 GLS HLX TOR1AIP1 TRAF6 ZFYVE16 FBXL5 EFCAB14 KLF7 DOCK9 CXCL2 SMAD7 GCA CRIM1 HCK RPS6KA2 MOB4 MYO1C ARL6IP5 VAMP3 PSEN1 MAGI2 RABGAP1 IFNGR1 STX7 IFRD1 KLHL18 MORC3 RPS6KA1 GRSF1 YTHDF3 BAZ2B VAMP4 MIA3 GALC HBP1 TERF2IP FCGRT STX12 SBSPON N4BP2L2 CLCN6 ATAD2B ARAP2 CEBPD ESYT1 METTL7A DAPK1 CD19 RASSF8 LYST CYTH1 DOCK4 IL16 RNF13 EVI5 FEZ2 LYZ SETX FAM8A1 ZFP36 CD69 C6orf62 MTSS1 TRIM13	down	***
GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	0.0000001	0.0000033	0.6901325	0.4448992	1.992956	169	CEP72 CDC45 TICRR POLQ KIF18B BRCA1 ECE2 E2F8 CDCA8 AURKB ACAD9 SLC6A3 FIGNL1 MCM4 MCM2 EIF3B MIS18A CCDC150 NLE1 DPY19L2P2 RHNO1 POLD2 GPSM2 CHAF1B BRI3BP BLM CCDC136 PSRC1 NCAPG2 DDX51 MRPL37 SERTAD4 ATIC UNG MRPS2 FEN1 SSX2IP ACTR3B SPAG5 SNRNP25 MYO19 TUBG1 DHODH SLC37A4 UBE3D DOK4 DTYMK HDAC1 TJAP1 NRF1 NUP85 KLHL32 GPATCH4 POP7 MCM6 MALSU1 DDX23 LTV1 EXOSC5 STK39 AP4B1 WDYHV1 GLO1 CISD3 CCDC167 ZWILCH MRPL9 LLPH TARBP2 MTHFD1 SEPHS1 CHERP	up	***
GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_DN	0.0000000	0.0000006	0.7337620	0.4433604	1.991248	175	BDH1 FANCI BUB1B CENPF GGCT TTF2 SORD PHGDH TTK GINS1 CDK4 SLC27A2 TRAIP NIPSNAP1 PLK1 AURKB ESPL1 GAPDH MCM4 MCM2 TYMS UMPS MYBL2 ORC1 CCT6A SHMT2 XPOT NCAPD2 ZWINT MELK NDUFB8 HMMR CHAF1A EEF1E1 TOP2A AURKA RAD54L PKM MCM3 RAD51AP1 BLM IDH2 PARP1 THOP1 CKS1B UNG EZH2 MRPS12 FADD ST14 TUBG1 FAH PSMA5 SNRPA CDC7 PFAS AHCYL1 MRPL28 FAM161A HAX1 SLC1A5 NEFH GOSR2 AP2S1 PYCR1 PRIM1 ECHS1 TMED9 CPOX MTHFD1 TP53 PCBD1 SNRPC BCAT2 ENO1 CYB5B SRM BAG2 PLK4 GSTP1 ADSL TOMM40 PMVK CRYZ	up	***
GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0000000	0.0000010	0.7195128	-0.3742264	-1.989652	180	ZMYND15 OLR1 OSBPL11 SNX10 COQ2 YPEL5 PPM1D PILRA TMX4 PTS TACC1 LATS2 RASGRP4 ZNF410 LCP1 SERPINB9 C1orf162 TOR1AIP1 SIRPA SPI1 CD58 TAPT1 MAP2K3 CDADC1 ZSWIM6 NFKB1 P2RY2 KCTD20 TLR4 ARAP3 TM6SF1 DUSP1 DSE MYH11 KPNA3 CALM2 CNOT6L CDKN2AIP HCK CREM OASL HCST OSBPL9 TYROBP SKIL FRYL TMEM167B CDK17 AZIN1 VAV3 SERPINB1 NAB1 IFNAR1 STK40 XKR8 TAB2 SP100 PSME4 GNMT GIMAP4 SMAD4 DNAJA2 JDP2 CHIC2 CLIP1 SLC19A2 MAPK1 FHOD1 FAM8A1 UBE2W DR1 ATP2B4 MAP3K1 WDR26	down	***
GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP	0.0000001	0.0000019	0.7049757	-0.3738211	-1.985987	179	SMAD6 CXCL3 IL1A CPEB2 IL1B F2RL3 EGR2 GTF2E2 IL1RN MOB1B IER2 SPG21 TRA2B BTG2 EIF5 PPP3CA NR4A1 NFE2L2 NDEL1 SRGN BTG3 ATP6V1H PDGFA RHOB IL10 RAB12 LIN7C PLAUR CDKN1A CXCL2 DUSP1 ZNF706 COPS4 CPLX1 ETF1 SGK1 SOCS3 C2CD2 STAT4 KCTD12 JUNB DNAJA1 PPP1R15A DHX15 IFRD1 EEA1 CD83 DDX5 ATP13A3 FOS PELI1 EHD1 TGIF1 PIM1 STK40 ETS2 IST1 ARPP19 ICAM1 HSP90AA1 RBM18 HNRNPK NFKBIA TNFSF9 EGR1 SERPINE1 CLEC4E NUP88 PIAS2 KCMF1 TES DLD IRF1 CUL2 MEF2D	down	***
GSE29618_BCELL_VS_PDC_UP	0.0000000	0.0000012	0.7195128	-0.3770453	-1.984692	170	SWAP70 CD55 LY86 PLEKHF2 BACH1 BCL2A1 CD22 IER2 TXNIP DPEP2 ATP2B1 MS4A1 CD37 RHOB PTPN12 EIF1B SYNPO FOXO1 YBX3 KLF7 CLIC4 LAPTM5 PTPRC DUSP1 HES1 IL24 ARHGDIB BTG1 PKIG ELF1 PHTF2 RAB8B PIKFYVE CD48 JUN SH3BP5 JUNB SNX2 CD83 TRAK2 IGKV3-20 CDK14 PLCG2 PELI1 KLF2 PTP4A1 CR1 GSAP PDLIM1 IRS2 KCNA3 MACF1 BMP2K CCR6 IER5 CDC42EP3 SP100 SCPEP1 ICAM3 CD19 NFKBIA LYST MMD AIM2 BANK1 PMAIP1 EGR1 CDKN1B NR4A2 PLEKHA2 TUBA1A CD69 CD79B PAX5 MTSS1	down	***
GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0000002	0.0000041	0.6901325	0.4427254	1.983218	169	TRIP13 KIF20A ASB4 PARPBP TROAP CHEK2 BUB1B NEK2 IGF2BP3 UBE2T CPSF6 KIF18B GAL3ST1 ZP3 GINS1 CDCA2 CDK4 ANLN POLE STIL IFT27 PTTG1 ECT2 E2F3 UHRF1 HOXB7 LSM5 EXO1 KCNN4 SMAGP CENPL PCDHGC4 RAD54L KIF11 FANCD2 CDC25C PFN2 PYCR2 LIG1 ORC6 MSI1 DSCC1 PPIL1 KNSTRN NCAPG2 CDKN2C FAM135A GMNN UNG NCAPG IGHG1 CENPP PA2G4 SPEF1 CCNE1 ESCO2 PKP4 ASNS NT5M CENPK CENPV TMCO4 SMIM6 C5orf22 C1orf122 ALG8 JAKMIP3 CCNA2 PRIM1 PRR11 ACKR2 RAD51 ZWILCH ARHGAP11A MXD3 VDAC3 SLC12A2 RASGRF1 ANKMY2 NEIL1 TMEM256 LXN ERLIN1 NCAPH TFB1M RTN4IP1	up	***
GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN	0.0000000	0.0000009	0.7195128	-0.3712743	-1.979922	182	SIDT2 FAM167A FYN BACH1 S1PR1 ZBTB2 FAM49A ACER3 KIAA0355 SLC44A2 ATP2B1 RRAGC UBL3 MAP3K8 REV3L FOXJ3 BNIPL EPB41L2 ITPRIP DUSP3 REST TMED5 CLIC4 NR1D2 TEF M6PR ADIPOR2 DEGS1 AFF1 CNOT6L SRF BTG1 SLC25A25 RYBP RBM34 SH3BP5 CUL4A PLK3 EPC1 WTAP IFRD1 IRF8 MSANTD2 GTDC1 DENND4A CEBPZ ZBED5 MAPK8 CD74 DCAF5 SERPINB1 VPREB3 TEC TSC22D1 NAB1 STK40 NBEAL1 CDC16 RIPK2 BRWD1 SCPEP1 PLGRKT TBCEL MAFK DOCK10 C21orf91 GIMAP4 ZFAND2A DNAJB5	down	***
GSE22886_NAIVE_BCELL_VS_DC_DN	0.0000001	0.0000013	0.7195128	-0.3718654	-1.979025	184	EPAS1 SLC31A2 HMOX1 RAPGEF2 TRPV2 CCDC88A RTN3 CITED2 FLVCR2 MKNK1 EPB41L3 PILRA CD36 PLA2G7 MAN2B1 CLEC7A IFI30 KLF10 GLS SLC7A11 ABHD6 SIRPA ZMYM6 TFEC SRGN CD58 ZMIZ1 MTMR6 GAA SLC7A8 CEBPA PLBD1 RIT1 TM6SF1 PLEKHB2 FCER1G PINK1 DSE TM9SF2 IL7R VAMP3 PGD SLCO2B1 PPA2 MITF RHOG SDHD SNX1 TNFSF13 PEA15 ATXN1 NQO2 GABARAPL1 FCGRT ZNF267 GPX3 VASH1 ARRB2 RTN4 TIAM1 LRP12 SOAT1 GLRX2 SNAP29 SAMSN1 DOCK4 HEBP1 EHD4 FEZ2 ZFYVE26	down	***
GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	0.0000001	0.0000033	0.6901325	0.4414198	1.972930	165	DDX11 KIF20A DEPTOR BUB1B CCDC34 POLQ DEPDC1 PIF1 TTK ANLN NUF2 CENPA ECT2 CCNB2 UHRF1 SLC35E3 XPNPEP1 CDC25A PRC1 ORC1 ZFYVE19 ZWINT SPDL1 WDR90 SDR16C5 MELK BUB1 AURKA EME1 IQCD MPHOSPH9 WDHD1 GPSM2 CDC25C TOPBP1 ORC6 HES6 SPC24 PSRC1 NCAPG2 NUSAP1 KCTD7 E2F1 NCAPG NEIL3 LRRC37A2 SAPCD2 FANCG CCNE1 CEP192 DCLRE1C TACC3 TK1 CHTF18 PCDH9 SASS6 PGBD5 CDC20 PEX5 RAB15 ATAD2 CYTH2 SLC2A5 ZMYND19 AGBL5 MXD3 CENPE SYNE2 SFXN4 E2F7 ZNF831 DDB2 ZNF367 ALPK1	up	***
GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN	0.0000002	0.0000052	0.6749629	-0.3762530	-1.972524	163	CD55 INPP5K YPEL5 STX11 CCNL1 TOE1 CHMP1B BTG2 KLF10 NR4A1 CD37 TIPARP MAP2K3 CFD PRDM16 SRSF5 SAP30BP TPSG1 ZCCHC24 CPVL MAP1LC3B TLR4 DUSP1 RSL24D1 AKIRIN1 BTG1 S1PR4 ELF1 OASL SRSF3 MAP4K4 TREM1 PPP1R15A PTGER4 IFRD1 PABPC4 OSM SNRK KLF2 PTP4A1 USP7 ICAM2 FOSB CD74 RPL21 GABARAPL1 RNF2 JUND EIF3F CXCR4 SP100 SCPEP1 RPS13 ICAM3 DNAJA2 PMAIP1 AQP5 NR4A2 CRBN EIF3L	down	***
GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP	0.0000002	0.0000037	0.6901325	-0.3752752	-1.970848	164	ABHD5 SPN SNX10 PTPRE CD44 MYADM FAM49A IER2 ZEB2 ANXA1 ENTPD1 ZDHHC2 SERPINB9 LAIR1 NR4A1 IL18R1 MPHOSPH6 SRGN BAG1 AHNAK CASP1 YBX3 COQ10B MAP1LC3B ITGAX ID2 CCL4 PRF1 PLEK DSTN INSL6 CALM2 MTPN CD48 CCDC50 IFNGR1 GMFG COBLL1 TBX21 NKG7 KLRC2 PIK3AP1 GIMAP1 SMPDL3B CHPT1 GSAP DUSP5 ATP6V0C NQO2 PHF11 GEM IL18RAP YAF2 CDC42EP3 ARHGAP18 ING2 TNFSF9 RORA PMAIP1 CX3CR1 ITGAL ITGB1 ZYX S100A8 NDFIP1 MICAL1 SPTY2D1 S1PR5 GPR55 CRIPT ATP2B4 NFIL3 RPA2 ATF6 DOCK5 TTC39B MYO1F KLRC1 F2RL2 SLAMF7 LEPROT	down	***
GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP	0.0000002	0.0000045	0.6901325	-0.3759597	-1.968468	160	HSPB7 ATXN3 BACH1 YPEL5 RPL23AP53 KCNN3 NR3C1 NUMB EIF4A1 CHMP1B PICALM ANXA5 SIRPA NFE2L2 AKT3 TMEM41B ZFYVE16 BTG3 UBE2D3 MOAP1 MEFV SNIP1 PNRC1 ZBTB43 UBE2B PER1 DNTTIP2 MATK IL7R SMNDC1 USP16 TOPORS NINJ1 DCP1A FLT1 IL6 COPS2 GABPA PHF10 ARHGEF10 DHX15 AGFG1 SLC3A2 ADNP2 AZI2 USP7 NAPG BTBD7 TEX14 PIK3C3 GATA6 PHF2 RXRA ZNF143 CEP170 SF1 MEX3C NABP1 SFPQ DNAJB5 RABGEF1 ADAMTS7 UBAP1 UBA6 ZYX ECD ZNF654 UBE2W UBE3A DDX21	down	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP	0.0000002	0.0000048	0.6901325	-0.3758114	-1.967475	162	IL1A DENND5A USP12 AQP9 SFR1 BCL2A1 AGPAT4 FAM49A RFTN1 SLC7A7 MTF1 TNIP3 RNF144B PTX3 SLC25A37 AKT3 CASP5 IL10 TBC1D9 TNFSF15 DENND3 SOCS2 CLIC4 NFKB1 P2RY2 CXCL2 ZBTB43 HES1 TP53BP2 IL24 PROCR KANK1 HCAR3 FLT1 IL6 SOCS3 STAT4 SH3BP5 HRH1 WTAP ELOVL7 ENPP4 HSPA13 OSM FSD1L TNFRSF9 ACSL1 AZIN1 SAV1 EHD1 SERPINB1 FPR2 PIM1 ETS2 CCL20 MIR155HG IER5 CDC42EP3 PLGRKT MAP3K4 BCAT1 NFKBIA MAGI2-AS3 MCOLN2 TRIM36 RABGEF1 SLC16A10 SVIL DCUN1D3 OSGIN2 MSANTD3 YRDC HEY1	down	***
GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP	0.0000001	0.0000017	0.7049757	-0.3723810	-1.967062	174	EREG TMEM52B RDX RTN3 QKI BMPR2 LAMP1 TGFBR2 FAM49A HBEGF RAP1A SERINC1 CNTD1 SLAIN2 NDEL1 GRN AKT3 ZEB1 FBXL5 ZMIZ1 ACSL3 KLF9 GAPVD1 UBQLN1 UBE2B RNF139 MFSD11 HTT PIK3R5 IL24 ANXA3 AKIRIN1 FAM102B NCKAP1L RAB8B VPS26A DHX15 FBXO11 SKIL ENPP4 CD83 MBNL2 ATL2 SLC10A7 HSF5 BTBD7 STXBP3 TAGAP MFSD12 KAT2B CCR6 EXOC2 ZNF583 TRAPPC8 PTCH1 ULK2 PAK2 ST6GAL2 LYST AIM2 IQGAP1	down	***
GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN	0.0000001	0.0000017	0.7049757	-0.3722642	-1.966445	174	HMOX1 MS4A7 SGK3 PECAM1 PPARG FABP4 HSD17B11 SLC25A30 TGFBR3 BCL2A1 GIMAP6 PILRA TXNIP EDEM1 RAPGEF4 SERINC1 PICALM PAG1 SIRPA RGCC TFEC TFRC MCL1 CST3 EPB41L2 AGO4 EPOR SDCBP PTPRO MEFV KLF4 STK17B C9orf72 RNF139 CD300C RPL17 MYO1C FRY CTSZ CELF1 JAK1 CDK2AP2 NDST1 PLCG2 SLC3A2 KLF2 SRSF6 SPOP IRF5 SORT1 AKIRIN2 KANSL2 RGS2 CPQ METTL7A STK4 JMJD1C CD3G SNAP29 CYTH1 MT2A RSU1 SMAD4 ARHGEF18 UBAP1 HIPK1 FTL ZFP36 FAM53B RNF167	down	***
GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN	0.0000001	0.0000028	0.7049757	-0.3704620	-1.966042	176	ZC3H12C GPR65 EGR2 GTF2E2 CITED2 FOSL1 CYB5R3 MKNK1 MARCO NEDD9 BCL2A1 IER2 PPP1R15B EIF1 MTF1 BTG2 MAP3K8 KLF6 NR4A1 NDEL1 CLK1 TIPARP RHOB IL10 SRSF5 BIRC2 RNFT1 ZFAND5 RMDN3 SNIP1 ATF3 CCL4 DUSP1 EVI2A SH2D2A BTG1 SLC25A25 AREG IL6 SGK1 SOCS3 KCTD12 PLK3 JUNB PPP1R15A FOS PELI1 JMJD6 TGIF1 IRS2 TPMT CCR1 KAT2B ETS2 GEM SERTAD1 CXCR4 TBCEL NFKBIA MAFK LYST DNAJB9 TLK2 TNFSF9 LDLR NABP1 SFPQ YTHDC1 EGR1 DUSP6 PRKCH SLC38A2 ZFP36 MT1E DNAJB1 TMEM11 BCL10 IRF1 NFIL3 TAF1D FASTKD5	down	***
GSE3982_DC_VS_TH1_UP	0.0000001	0.0000032	0.6901325	-0.3696032	-1.961484	176	SMAD6 SIDT2 CD52 TAL1 THBD SLC6A12 LYL1 FCER1A RASAL2 PCOLCE2 C5AR1 CLEC10A SLC15A3 IGSF6 PILRA FGR LRRFIP2 CD36 ANXA1 CYB5A ANPEP ABHD6 RGCC SPI1 CFD ARRB1 MVB12B DRAM1 TPP1 TMBIM1 PDE8A CLIP4 GNAQ RUFY3 LMBRD1 CLN8 TMEM9B FLT1 CTSS C1QA CUL4A GAS2L1 PDE5A ZNF804A CR1 PEA15 CD1D CTNNAL1 CSDE1 ADPGK KYNU RGS2 SESN1 IL18 CES3 PARM1 IFFO1 SCPEP1	down	***
GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN	0.0000001	0.0000019	0.7049757	-0.3719456	-1.961143	173	SLPI ABHD5 GPR15 FABP4 SLC6A12 EGR2 CCRL2 AKAP7 SLC25A30 S1PR1 SLC15A3 P2RY13 MARCO NR3C1 FGR PLA2G7 SGMS2 GNGT2 TMEM204 EIF5 AHRR ZNF503 LITAF PAG1 SPRY2 SRGN BTG3 TUBB6 FBXL5 MSR1 FABP5 RAB12 BST1 PLBD1 NR1D2 CEP57 GCA INHBA MBD2 IL7R NUS1 PLEKHA3 SERPINB8 JUNB FAM43A OSM PTGER2 CD164 AZI2 CD74 UBXN2A CD1D TCP10L TGIF1 FPR2 CD86	down	***
GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP	0.0000012	0.0000208	0.6435518	-0.3787809	-1.960536	145	RAB11FIP1 EREG IL1A OLR1 SOWAHC PGC IL1B LRRC8C NUP54 EGR2 CRY2 FXYD2 SLC15A3 DYRK1A LRRFIP2 CD33 ZDHHC2 SLC7A11 NR4A1 SRGN SLC7A2 CSRNP1 BST1 SLC12A4 PDE8A CCL3 MGAT4A CXCL2 CCL4 HTRA4 KREMEN1 RBPJ FMNL2 NOTCH1 TREM1 DUSP8 OSM RNF24 EGLN2 ACSL1 AGFG1 SIGLEC1 MBP CD74	down	***
GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000002	0.0000045	0.6901325	-0.3690593	-1.960364	177	ZMYND15 OLR1 MCOLN1 DENND5A INSIG1 QKI TBC1D7 SLC15A3 BCL2A1 HPS5 EDEM1 EIF4A1 B3GNT5 LATS2 KLF10 TFRC DIABLO ZMIZ1 DUSP3 SGTB PLAUR MAP1LC3B SPAG9 NR1D2 C9orf72 ADIPOR2 OXSR1 FKBP15 MAFF SEC31A SNN RBPJ GZF1 RAB8B ARL5B STAT4 SKIL CD83 ATP13A3 SUCNR1 CLN3 SLC3A2 HIVEP2 AZIN1 SAV1 ZBTB1 NAB1 SOD2 LGALS3 GABARAPL1 NBEAL1 RIMKLB MFSD12 PDE4B BNIP3L IER5 ZBTB25 TXNDC11	down	***
GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN	0.0000001	0.0000019	0.7049757	-0.3723860	-1.960167	170	SLC31A2 ACP5 KMO TSPAN4 PECAM1 PTPRE LIPA ENG FIG4 PLEKHA1 YPEL5 IGSF6 TXNIP SLC7A7 CLEC7A IFI30 HLX SIRPA GRN ARRB1 CCL22 SRSF5 DAAM2 CDKN1A CD302 LBH FCER1G PIK3C2A PLEK PINK1 HCK VAMP3 CTSS CD48 CTSZ TYROBP CD83 HERC1 RHOQ TNFSF13 KAT8 TIMP2 MILR1 TSC22D1 CD86 CD81 LGALS3 CCR1 FCGRT N4BP2L2 ARAP2 RTN1 CXCR4 RIPK2 DHRS12 TBC1D1 METTL7A LIMCH1	down	***
GSE8515_IL1_VS_IL6_4H_STIM_MAC_UP	0.0000009	0.0000159	0.6594444	-0.3746248	-1.959734	158	CXCL3 DENND5A IL1B CCRL2 CDH13 PAFAH1B2 STX11 ALAS1 NCF2 SCARF1 RFTN1 LYRM4 BTG2 PTX3 SERPINB9 BTG3 TCF7L2 PPP3CC NFKB1 DOCK9 CXCL2 CCL4 UXS1 CCSER2 PLEK TP53BP2 MAFF SNN BTG1 KANK1 PKIG HCAR3 FRY CD80 IL6 FAM189A1 PSEN1 STAT4 PLK3 JUNB WTAP PTGER4 CCR7 CD83 REL ACSL1 EHD1 PDE4B CCL20 ICAM1 RIPK2 SIK3 TRAF1 MAP3K4 NFKBIA TNFSF9 GPR171 SYNPO2L	down	***
GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN	0.0000002	0.0000043	0.6901325	0.4383544	1.959229	165	FOXM1 KIF20A CEP89 CDC45 PARPBP NUP107 PRIM2 PIF1 TTK GTSE1 POLE STIL MSTO1 CDCA8 ECT2 UHRF1 MCM4 PMS2 MIS18A NCAPD2 MELK NUDT1 CEP55 TSGA10 CENPL NUP155 MPHOSPH9 WDHD1 FANCD2 CDC25C TOPBP1 CHEK1 AHCY CENPO RAD51AP1 SLC25A39 SPC24 FBXL8 CBX5 RFWD3 GMNN NEIL3 EZH2 DDT CENPP ULK1 PIAS3 DHX40 LMNB2 KIF22 GINS2 ANP32E KIF20B LRWD1 CEP128 ATAD5 CENPT CD2BP2 LANCL2 LSM4 ERGIC3 STK35 WDYHV1 ATAD2 STK38 ARHGAP11A CENPE PAICS SIAE TTC9C RIPK3 PPP2R5D C4orf46 NCAPH C9orf40 CNPY4	up	***
GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP	0.0000006	0.0000124	0.6594444	-0.3778947	-1.959100	146	SNX10 TTC7B CD44 MYADM IL1RL1 GNPTAB FAM49A ZEB2 ANXA1 CYP17A1 ARSB LATS2 ZDHHC2 LAIR1 IL18R1 PPT1 AHNAK TRIM46 PLEKHM3 CTSD ITGAX VIM HOPX ID2 CCL4 TEF PRF1 CALM2 EMP3 NDNF CCDC50 EEA1 DAPK2 COBLL1 TBX21 GPRIN3 NKG7 KLRC2 XYLT1 SMPDL3B CHPT1 GSAP ATXN1 LGALS3 POLK IL18RAP MS4A4A ARHGAP18 TOB2 HAVCR2 KLRK1 RORA GIMAP4 RSU1 CX3CR1 ITGAL ITGB1 PIK3CG ARHGEF12 ATP2B4 NFIL3 RPA2 DOCK5 CD226 TTC39B MYO1F MYO5A EMP1 TNFRSF1B ZC3H7A F2RL2 GZMK	down	***
GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP	0.0000000	0.0000008	0.7195128	0.4363986	1.958737	177	CEACAM1 TRIP13 HJURP BDH1 ELOVL6 NEK2 POLQ BRCA1 TTK TRAIP GMPS PLK1 MYBL2 CCT6A NCAPD2 CDT1 RUVBL2 EXO1 MKI67 EMC9 KNTC1 PUS7 FSD1 B3GNTL1 DNAJC9 CAD PHB PON2 FAHD2A UCK2 POLR3K NEIL3 CCDC88C EZH2 LRRC42 RNASEH2A ILF2 OSBPL3 MRPL11 SSRP1 CENPQ ASNS MAGOHB CCT7 RAD50 GEMIN6 SUPT16H PFAS TIMM13 MRPL28 PPCDC HEATR1 TDP1 LANCL2 DUS4L PSMB4 TCERG1 SUV39H2 PRIM1 RAD51 GRAMD1B SEPHS1 PAICS SNRPC NCAPD3 RAD1 PPP1R14B BRIX1 CYB5B AVEN MRPS16 DGUOK C12orf43 RWDD2B AP2B1 TIMM10	up	***
GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN	0.0000001	0.0000023	0.7049757	0.4356978	1.958041	176	GMDS NEK2 CCDC34 MPP6 PBK PIF1 TTK E2F8 ANLN CDCA8 AURKB DIO2 MCM4 TYMS CA12 PRC1 GLDC NCAPD2 SPDL1 NME1 RANBP1 MELK HMMR MRPL15 KNTC1 EME1 CDCA5 RAD54L CHEK1 ASS1 C7orf50 ACTL6A MAD2L1 RAD51AP1 DCTPP1 GNPDA1 FLNB PTPN3 INCENP RNF216 CKS1B CXCL14 RFWD3 CENPH C1orf112 SDCBP2 NEIL3 SPAG5 ETFB CCNE1 TACC3 OSBPL3 KIF22 TRIM37 TK1 DTYMK CASP7 GINS2 SAP30 MAGOHB HLA-A CDC20 ASRGL1 CKAP2 MCM5	up	***
GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN	0.0000006	0.0000124	0.6594444	0.4415652	1.954206	154	SLC16A14 CEP89 FBXW8 HOXD8 NEK2 APOLD1 SRGAP3 RACGAP1 E2F8 POLE STIL EFNA4 ESPL1 BCL2L14 SHMT2 FSTL4 CLSTN3 KNTC1 TOP2A EME1 NDUFS2 IFT43 CDCA5 SLC4A11 KIF11 KDELR2 MAD2L1 SPC24 PML FADS2 PPIL1 TXLNB NCAPG2 TMEM106C ASF1B CLMN C1orf112 NUDT2 SSX2IP CXCL17 HYKK DNMT1 CCNE1 KIF22 MLEC GINS2 ETV4 CDC20 HPD MGME1 ADAMTS12 CENPT CACNB3 GGT5 UNC119B LHX4 PRIM1 ACSF3 ARHGAP11A SUPT3H TONSL GMPR2 LOXL4 FAM78B MRPL20 KIF24 CASKIN1 PCGF2 HRAS GSTT2 KHDRBS2 LTK TOMM40 STARD10 PMVK	up	***
GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP	0.0000002	0.0000037	0.6901325	0.4358792	1.953212	167	MDM1 TROAP BUB1B IGF2BP3 KIF18B DEPDC1 DEPDC1B CDCA7 TTK IQGAP3 E2F8 GTSE1 ANLN PLK1 CDCA8 CENPA ESPL1 TPX2 FIGNL1 MCM2 ACY1 MAP2K6 NCAPD2 KIF23 MKI67 AURKA POLA2 SMARCAL1 KIF2C CDCA5 KIF11 SOX4 CKAP2L PIH1D1 PPP5C FADS2 INCENP ASF1B CDK1 POLE2 SUN1 E2F1 ANAPC7 SPAG5 VPS72 EIF6 DPP3 NMRAL1 SSRP1 TK1 CHTF18 HDAC1 EDARADD POLD1 RNF187 CKAP5 CDC20 MGME1 MED24 EIF3D IL12RB2 POLR2I LSM4	up	***
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN	0.0000001	0.0000024	0.7049757	-0.3703271	-1.949329	170	SLC31A2 ACP5 CD52 HMOX1 CD101 OSBPL11 PECAM1 HHEX MNDA LTA4H HSD17B11 MYD88 MSRA FUCA1 FRAT1 TMX4 CD36 TNS1 GRN EVI2B KIAA0513 KLF11 ARNTL VRK2 ITPK1 PAPSS1 EVI2A CPT1A MBD2 MPC1 VAMP5 KBTBD4 HEXB NCKAP1L PRCP ARL6IP5 RNF141 IDS RASSF2 CELF2 ICAM2 BIN2 SORT1 TIMP2 RPL21 CD86 MAP3K2 THAP11 CLEC2B PCCA COMMD9 BMP2K VASH1 CALHM2 CEBPD ALDH2 TBC1D1 IFFO1 METTL7A GLUL THEMIS2 CNOT8	down	***
GSE20715_WT_VS_TLR4_KO_LUNG_UP	0.0000002	0.0000040	0.6901325	-0.3687588	-1.943794	172	RBP4 EPAS1 TMEM100 LRRC8C FIG4 TMOD3 PCOLCE2 PRKAR1A MEF2A CD9 SEMA6D CD36 ANXA1 SSTR1 RAPGEF4 SERINC1 HSPB1 EIF4E BTG3 UBE2D3 PDGFA FBXO8 MTMR6 TBX4 NPNT ST3GAL2 ITM2B MAP1LC3B CLIC4 VIM CD302 CD53 CPT1A RNF149 SNAP23 GLUD1 JAK1 SNX2 PIK3R1 DDX5 MME SERPINB1 KCTD10 FPR2 ORC2 CSDE1 MR1 MBNL1 SOD3 GPX3 RTN4 CUL3 SAMSN1 TMCC3 GSPT1 GIMAP4 RNF13 DNAJA2	down	***
GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN	0.0000003	0.0000064	0.6749629	-0.3656588	-1.942301	177	CXCL3 STAC PHACTR1 SOWAHC IL1B RDX TXNL1 CCRL2 ARL8B IL1RN AGPAT4 RFTN1 PLA2G7 RRAGC HBEGF LMNA GM2A MTF1 SLC7A11 CLN5 ZFYVE16 TXN ATP6V1H TUBB6 CCL22 PXDC1 DAB2 ATP6V1D MAFG CDKN1A CXCL2 CCL4 ZBTB43 INHBA IL7R MAFF CRIM1 PI4K2A MMP19 CLN8 NINJ1 IL6 MITF STAT4 SH3BP5 GSTO1 WTAP CCR7 UNC13B ATP13A3 SLC3A2 RHOQ HIVEP2 TSC22D1 PIM1 SOD2 KYNU ZNF267 ETS2 ANKLE2 TEX10 TRAF1 BCAT1 GLRX2 PDE4A CAMSAP2 DOCK4 MT2A	down	***
GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_UP	0.0000001	0.0000019	0.7049757	0.4324282	1.942149	175	TRIP13 FANCI TROAP CCDC34 UBE2T CPSF6 NDC80 DEPDC1 DEPDC1B IQGAP3 GTSE1 IFT122 KIF14 STIL CDCA8 ECT2 ESPL1 TPX2 ARHGAP33 TYMS PRC1 CCNF DCTN2 CCDC150 MELK SPAG16 EME1 SAE1 KIF2C E2F2 POC1A CDCA5 RAD54L GPSM2 WDR66 CDC25C CKAP2L PKMYT1 CKS1B CDKN2C HPS4 NUSAP1 CBX5 HDGF CENPJ BIRC5 SPAG5 SAPCD2 DIAPH3 RANGAP1 CCNE1 TRIM24 DLGAP5 TACC3 DTYMK GINS2 TCEA1 SPA17 TAPT1-AS1 CDC7 PEX5 UBL7-AS1 MRPL51 CYTH2 PRDM10 CARHSP1 ARHGAP11A SRP9 RPRD2 MXD3 TCF3 SEPHS1 CDC25B TUBA1C ZNF367	up	***
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_DN	0.0000003	0.0000058	0.6749629	0.4346215	1.938015	163	TRIP13 CDC45 MCM10 TROAP CCDC34 PBK PRIM2 DEPDC1 MRPL46 GINS1 CDK4 SNF8 PLK1 NUF2 CDCA8 AURKB SFXN1 CCNB2 FIGNL1 SHMT2 SPDL1 NME1 RANBP1 HMMR MKI67 KIF15 BUB1 AURKA EME1 MCM7 RRM2 ORC6 MAD2L1 CKAP2L RAD51AP1 SPC24 DSCC1 CKS1B ASF1B CDK1 POLE2 UCK2 BIRC5 GMNN ADAP1 POLR3K SLC25A13 PSAT1 SPAG5 ETFB CENPP TUBG1 PSMA5 KIF22 AGPAT5 PRMT7	up	***
GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN	0.0000002	0.0000047	0.6901325	-0.3676253	-1.937819	172	SLPI PECAM1 LPXN THBD LMO2 GPCPD1 S1PR1 STX11 GNPTAB CD22 NFATC3 CD36 B3GNT5 ZDHHC2 RANBP9 FOXP1 RB1 TMEM123 CD93 HERC3 FBXL5 TAPT1 DGKE PRKD3 PLEKHM3 ATP6V1D CCND2 PPP2R5A HLA-DQA1 AFF3 SNN PIAS1 ARHGAP17 PKIG ELF1 WASF2 CTSS SLC14A1 OSTM1 WTAP CCR7 STX7 UBAC2 PRKCE FRYL TINF2 GPR3 PRKCG CD74 FAM204A PIK3AP1 VAV3 KCNA3 RGS2 GPR18 BMP2K ANKLE2 HSPA2 ALDH1B1 SPIB RIPK2 B3GNT2 CECR2 CYTH1	down	***
GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN	0.0000002	0.0000048	0.6901325	-0.3647368	-1.935658	176	HSD17B11 LMO2 CCRL2 ST3GAL6 BCL2A1 CD22 ANXA1 SPG21 ENTPD1 PPP1R15B SERPINB9 GATA3 IL18R1 SRGN BTG3 UBE2D3 RAB14 AHNAK MPEG1 RNFT1 ITM2B ARNTL SOCS2 GRK5 PLBD1 FAM49B HOPX ID2 PLEKHB2 PRF1 EVI2A VAMP5 IL7R SMNDC1 HLA-DQA1 ACTR2 HGSNAT SACM1L ASNSD1 NXF1 KCTD12 ETS1 PTGER4 EEA1 RASSF2 RIN2 IRF5 AP1G1 SBF2 RELL1 DOK2 GNA13 RGS2 SERINC3 PPID ICAM1 IL18RAP SFT2D1 ARIH1 G3BP2 OSER1 CD19 CUL3 KLRK1 DNAJB9 NABP1 SPATA13 EIF4G2 CYBA CTSH	down	***
GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP	0.0000016	0.0000274	0.6435518	-0.3688944	-1.929758	158	SIK1 OTUD1 LDB2 YPEL5 CCNL1 RBM7 HBEGF TM2D3 SDE2 BTG2 ZBTB21 NR4A1 MED26 NFE2L2 NDEL1 TIPARP CSRNP1 ITPRIP COQ10B ARNTL ATF3 BCLAF1 SMNDC1 ANXA3 RASGEF1B SIAH1 CREBRF ETF1 DCP1A GZF1 TMOD1 NECAP1 ETV3 PLK3 JUNB DHX15 GPR183 N4BP3 OSM REL SNRK FOS PTP4A1 PSMD12 PPTC7 CHORDC1 PHF3 SRSF4 SKIDA1 RGS2 PDE4B IST1 CCL20 JUND NR2E3 CXCR4 JMJD1C MAFK C20orf203 DNAJB9 CNTNAP3B ZNF326 PIM3 YTHDC1 ICOS EXOC8 ZFP36 CD69 LAMP3 TSC22D2 ZBTB46 MEF2D RAB1A NR4A3 JARID2 KBTBD2 SREK1 IVNS1ABP WHAMM SNX29P2 RELT FEM1C CYTIP KLHL29 PLCL1	down	***
GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP	0.0000009	0.0000163	0.6594444	-0.3673935	-1.926078	163	ABHD5 SNX10 PTPRE TTC7B CD44 CTSW MYADM AQP9 SLC39A8 IL1RL1 GIMAP6 GNPTAB ZEB2 ANXA1 ATP2B1 CYP17A1 ARSB LATS2 ZDHHC2 LAIR1 IL18R1 PPT1 AHNAK PLEKHM3 CTSD ITGAX VIM ATP6V0D2 ID2 PRF1 DSTN IL7R PIK3R5 CALM2 EMP3 MYLIP HCST CCDC50 PTGER4 EEA1 DAPK2 COBLL1 TBX21 NKG7 KLRC2 XYLT1 PIK3AP1 SMPDL3B GSAP ATXN1 LGALS3 IL18RAP SEMA4A ARHGAP18 RIPK2 HAVCR2 KLRK1 RORA GIMAP4 CX3CR1 UBA6 ITGAL ITGB1 ARL4D S1PR5 ATP2B4 RPA2 DOCK5 GZMB MYO1F KLRC1 MYO5A TNFRSF1B F2RL2 SLAMF7 GZMK	down	***
GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN	0.0000003	0.0000058	0.6749629	-0.3653804	-1.925986	172	SMAD6 OLR1 PPARG IL1B MIR22HG THBD ENG FYN AATK RBM14 MEF2A EIF4A1 ADA LMNA CSRP1 ANPEP PTX3 LAIR1 SRSF2 MPHOSPH6 CRK TMEM41B TIPARP FABP5 HNRNPA3 LIMS1 PLAUR THBS1 CCL3 NFKB1 CXCL2 ATF3 CCL4 ZBTB43 DUSP1 ARL4A MATK ANXA3 PI4K2A SRF EMP3 KANK1 SERPINB8 SH3BP5 GAS2L1 MN1 RHOG PPP1R15A CD83 GPR183 YWHAZ PPM1F CALM1 FOSB	down	***
GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN	0.0000005	0.0000103	0.6594444	-0.3614443	-1.919915	177	DENND5A SIK1 ST3GAL6 S1PR1 MAL LAMP1 HEG1 TXNIP TOE1 ADA EIF1 BTG2 LITAF HNRNPDL CLK1 SRGN PDE4D CD37 MOAP1 SRSF5 SDCBP TPP1 LAPTM5 RBMS1 UBE2B PER1 RNF139 BCLAF1 AFF1 NCOA1 BTG1 RBM39 S1PR4 PPP2CA ELF1 SGK1 NXF1 PLK3 JUNB JAK1 DUSP8 WTAP DDX5 THUMPD1 HERC2P3 CLN3 SNRK CALM1 SRSF6 HBP1 HNRNPH3 FCGRT TOB1 RGS2 PDE4B RBL2 CCDC69 TPT1 CXCR4	down	***
GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP	0.0000001	0.0000026	0.7049757	0.4275703	1.919112	177	RUVBL1 CDC45 MCM10 CENPF NUDCD3 TSFM GINS1 RACGAP1 POLE TTC26 PLK1 CDCA8 CENPA GAPDH MYBL2 DTL CDT1 CCT2 SPDL1 HAUS5 BZW2 EXO1 MKI67 KNTC1 POLD2 RBM28 PDCD5 LIG1 BLM MEOX1 CNPY2 CKS1B NCAPG2 TMEM106C PABPN1 EXOSC2 ATIC POLR3K FBXO41 MCAT MRPL17 MRPS12 RNASEH2A ILF2 ATP6V0E2 TACC3 LONP1 DTYMK SPAG1 MAGOHB CCT7 RAD50 SUPT16H NPRL3 DUS1L POP7 FAM136A BCL2L1 MRPL24 NOC4L GINS3 LSM4 PRKD2 PRMT5 MICAL3 PMS1 GRAMD1B RPUSD2 CIAPIN1 TARBP2 LIF NMT1 NCAPD3 ENO1 NUP210 DNM1L NUP93 COX17 WRAP73 SRM BAG2 CLPP HINT1 TMPO IMP4 DCLRE1A CS HNRNPAB CRCP NUP37 FIBP CTPS1 TMEM14A	up	***
GSE7852_LN_VS_FAT_TCONV_DN	0.0000007	0.0000130	0.6594444	-0.3619283	-1.917322	175	SEMA3G CXCL3 DENND5A SIK1 PLEKHF2 MYADM SRSF7 IL1RL1 BCL2A1 AGPAT4 ABCB1 ENTPD1 NR4A1 BTG3 TXN IL10 CFD DGKE CASP1 KLF9 STX3 SOCS2 SNIP1 TMBIM1 CDKN1A ATF3 HOPX PLEK PRKRA HCST KCTD12 SNHG8 UHRF2 PPP1R15A HSPA13 COBLL1 TBX21 DENND4A TAGLN2 HIVEP2 RUNX3 PKD2 FOSB NKG7 DCAF5 TSC22D1 ZCCHC10 DUSP5 SOD2 TOB1 ACYP2 RGS2 RXRA SPARCL1 CDC42EP3 CXCR4 FBXO30 HIGD1C S100A4 TTC19 SAMSN1 RORA IQGAP1 EHD4 ATF4 NR4A2 ITGB1 TRIM13 TSC22D2 ATP2B4 NFIL3 IMPACT AKAP13 METRNL NFKBIZ GZMB RNF19B MYO1F SLC25A28 PNP DENND4C KLRG1 EFEMP1 HSPA5 ZC2HC1A FARP1 FASLG TMEM64	down	***
GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP	0.0000002	0.0000047	0.6901325	-0.3629385	-1.917183	174	ACP5 KMO USP12 SPN CAT RDX ARHGEF15 HSD17B11 SAMHD1 ST3GAL6 CORO1C CALCRL SLC39A8 PLEKHA1 SYS1 CD36 SLC44A2 MAN2B1 ARSB LIFR ABCG2 RNF125 CD93 SPI1 STAT5A DUSP3 DGKE PXDC1 KLF7 VIM TM6SF1 AKIRIN1 CNRIP1 TMEM9B S1PR4 ASNSD1 PSEN1 HECA STAT4 APBB2 PALM PI4K2B GMFG GYPC FAM43A ACSL1 YPEL2 EHD2 EPPK1 ALDH3B1 PPP2CB KCTD10 VPREB3 GALC ATXN1 COL15A1 STK40 ARPC2 ARHGAP18 GPD1L SCPEP1 FNIP2 MCOLN2 GPR171 LPAR6 BANK1 MAN1C1 CHP1 UBR2	down	***
GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP	0.0000003	0.0000065	0.6749629	-0.3611907	-1.916838	176	SIDT2 MYO7B SGK3 PECAM1 PTP4A2 FYN VAMP2 MKNK1 ZBTB2 IL23A GINM1 ATP2B1 TACC1 EIF1 ACOT2 RNF125 CSGALNACT2 FOXP1 ADRB2 HNRNPDL CD93 IL10 ITPRIP MAFG KLF7 CEP57 CLK4 ELMSAN1 IL7R USP16 IKZF5 CDKN2AIP FAM102B NRROS GPBP1 MOB4 NXF1 NECAP1 ETS1 EPC1 SKIL UBAC2 RC3H1 TMEM167B REL SNRK CELF2 AZI2 SRSF6 ING3 BAZ2B CDC37L1 DUSP5 ADPGK SERINC3 TAGLN GEM PCM1 SF1 TOB2 CREBBP ULK2 CEPT1 SKI DAZAP2 PUM1 ZNF326 KALRN CDKN1B	down	***
GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN	0.0000007	0.0000140	0.6594444	-0.3610899	-1.912880	175	IL1A CXCL16 SNX10 INSIG1 TBC1D7 ZCCHC2 CIR1 BCL2A1 SCARF1 RCHY1 PILRA FGR ZEB2 RRAGC CARD16 MCTP1 SLC7A7 ADAM17 MTF1 RNF144B TFRC EIF1B STAT5A MAFG NPR3 ATG7 NFKB1 PNRC1 PRF1 CCDC59 INHBA PIK3R5 PROCR LACC1 ELF1 MAML2 SERPINB8 PSMA1 ARL5B SH3BP5 CPEB4 HRH1 MAP4K4 OSTM1 WTAP PNPLA8 PTGER2 CXCL5 ADNP2 PIK3AP1 DUSP5 SOD2 ETS2 ZNF438 IER5 MS4A4A HSP90AA1 TAB2 RBM18 G3BP2 HNRNPC CEPT1 LINC00884 SLFN11 SPHK1 RABGEF1 SLC16A10 MB21D2	down	***
GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP	0.0000003	0.0000057	0.6749629	-0.3597602	-1.912740	180	CXCL3 KMO SC5D CLIC3 IL1A STAC SLC12A6 OLR1 IL1B FBP1 LPL RASAL2 CORO1C ALAS1 BCL2A1 NCF2 IL1RN IGSF6 FGR HEG1 ASAP1 TNIP3 RGCC BTG3 TXN ATP6V1H TMEM38B TUBB6 EPB41L2 PTPN12 CCL22 ADO PTAFR PLAUR CLIC4 RIT1 VIM CCL4 ALOX5AP INHBA MAFF CRIM1 CD80 IL6 IL2RB PPA2 JUN MAP4K4 CYCS	down	***
GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_UP	0.0000002	0.0000051	0.6901325	-0.3633532	-1.912620	170	ACP5 PDLIM2 LRRC8C LIPA FCER1A FLVCR2 CYB5R3 TET2 TGFBR2 SPCS3 PLA2G7 STARD4 LATS2 HSPB1 HLX ZMYM6 TXN TAPT1 AHNAK LIMS1 SLC46A2 TMED5 MGAT4A ID2 DSTN CALM2 DEGS1 CMTM6 FAM102B RBPJ RYBP PHTF2 UTRN CYB5R1 C20orf194 TYROBP HSPA13 FRYL ZBTB24 ENTPD4 FAM177A1 RNF24 SLC25A24 BTBD6 CALM1 ZFAND6 LGALS3 RGS2 ZNF267 RAB5A PIP4K2A DAPK1 TLR10 DOCK10 DAZAP2 TRIM36 CYBA CSF2RB C1QB CTSH CAPZB CLOCK ZYX EXOC8 KMT2E ATP1B1 CALR MICAL1 RGS12 GLIS2 ZFYVE21 CCNYL1 NTAN1	down	***
GSE12366_GC_VS_MEMORY_BCELL_DN	0.0000003	0.0000059	0.6749629	-0.3592753	-1.910162	180	CLIC3 SLC12A6 CD55 RDX GPR65 BACH1 PLEKHA1 LAMP1 IL23A SPCS3 TXNIP MAN2B1 ASAH1 ENTPD1 NAAA PARVG JAM3 KPNA5 RHOB ZMIZ1 DGKE PTPRO ITM2B ZADH2 ITPK1 CDKN1A CCND2 DUSP1 N4BP2L1 SNN SERTAD2 S1PR4 CD48 LIMD1 IFNGR1 CCR7 GPR183 SERPINB6 TSPYL1 KLF2 FOSB CR1 RPL21 ATXN1 ADPGK MACF1 N4BP2L2 PLEKHO2 POLK PDE4B CCR6 MOB3B SESN1 IER5 ISCU DOCK10 SKI LTBP3 NABP1 EIF4A2 BMI1 PHYH PLAG1 CRTAP CLIP1 TGOLN2 ITGB1 RAB37 DRAM2 NDFIP1 CSNK1G3 TES FNDC3A STARD5 MAP3K1 KLHDC1 ATF6 DUSP22 CFLAR FAM89B MYO1F	down	***
GSE3039_CD4_TCELL_VS_B1_BCELL_DN	0.0000013	0.0000230	0.6435518	-0.3640454	-1.908525	163	SIRPB1 SLPI SLC31A2 MCOLN1 GLIPR2 IL1B CD44 KCNN3 CD9 IL1RN LAMP1 SLC11A1 RHOA TXNIP CD33 CLEC7A ANXA5 ADIPOR1 ADRB1 STOM SIRPA CD93 MCL1 TMEM38B FOXC2 SDCBP MEFV MPEG1 BST1 ITM2B USP2 FAM49B CTSD CCL4 CD302 CD53 FCER1G CD300C HTRA4 BTG1 CABLES1 HPGDS TYROBP STX7 LPCAT2 CAP1 ZBED5 MCAM PIK3AP1 TIMP2 ATP6V0C CNTNAP1 SOD2 CCR1 MR1 TCTEX1D4 TNFAIP8 GSTM5	down	***
GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN	0.0000006	0.0000120	0.6594444	0.4277452	1.903488	161	TRIP13 SLC16A14 COL24A1 GPT2 BUB1B CCNB1 PBK CCDC113 PHGDH GINS1 E2F8 STIL NUF2 IGKV4-1 PTTG1 CDC6 CCNB2 SPATS2 GLDC MYL6B CLPTM1L HMMR MKI67 BUB1 IGLV1-44 RRM2 KDELR2 CHEK1 PERP PHB EFCAB11 CDK1 NCAPG SPAG5 DLGAP5 IGLV6-57 GALK2 TIGD6 IGHM FKBP14 CEP128 DENND5B CDC20 CENPM EFHC1 FAM174A NT5DC2 SLC2A5 DCPS DOCK3 SHCBP1 RNF121 OSBPL10 GADD45GIP1 FAIM IGLV3-19 SRPRB ZBTB32 CBWD1	up	***
KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN	0.0000002	0.0000053	0.6749629	-0.3585965	-1.903307	178	WEE1 DENND5A LRRC8C SNX10 CLDND1 TTC7B CD44 CTSW ST3GAL6 AQP9 CYB5R3 BCL2A1 FGR ANXA1 KLF10 KLF6 PRSS12 GATA3 IL18R1 CRTAM TXN PPP3CC AHNAK CASP1 YBX3 KLF4 BCHE CTSD ITGAX HOPX ID2 CCL4 RECK PRF1 MBD2 SH2D2A N4BP1 IL7R MAPRE2 CD160 GABARAPL2 GSTO1 EEA1 DAPK2 CD7 DYM CST7 FOS KRTCAP2 FOSB CHPT1 PIM1 FCGRT TOB1 JUND RNF138 IL18RAP	down	***
GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN	0.0000003	0.0000064	0.6749629	-0.3602893	-1.903189	174	SASH1 TAL1 HHEX GLIPR2 LPXN GPR65 SIK1 OTUD1 HEATR5B MYD88 S1PR1 HSPE1 NFIX RNF144B ABCG1 BFAR SPRY2 PPP1R13B CWC22 ITPRIP CASP1 SLC7A8 ARNTL SOCS2 ITPK1 PDE8A MGAT4A CDKN1A AXL RSL24D1 SNN TDRD7 HCK USP25 ARHGAP17 MCMBP PLEKHA3 NECAP1 ETV3 OSM MORC3 FOS PELI1 CD164 AZI2 RIN2 TCF4 AP1G1 KHDRBS1 GNB4 UTP3 KAT2B TSPO IL18 XKR8 PUS10 G3BP2 FNBP4 CYTH1 TMCC3 FEZ2 DNAJA2 SPATA13 HAT1 PHYH ZNF800 ENDOD1 PLEKHA2 SNW1 PPIP5K2 XRN2	down	***
GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN	0.0000003	0.0000056	0.6749629	-0.3584844	-1.902712	178	SNX10 RAPGEF2 CLDND1 CD44 TXNL1 LONRF1 SLC39A8 ARL8B WBP4 LYRM4 WWC2 DNAJC18 BMP1 CARD16 ADA TNIP3 RANBP9 CLN5 NDEL1 BTG3 ATP6V1H CD58 PTPN12 CSRNP1 CASP1 PLAUR PLEKHM3 DRAM1 SOCS2 VRK2 CLIC4 FMNL3 NFKB1 CDS2 IRAK2 PNRC1 INHBA N4BP1 CMTM6 HCK BTG1 SLC25A25 INO80C ETV3 PSMA1 WTAP IFRD1 LYRM1 PSTPIP2 OSM TNFRSF9 TAGLN2 ACSL1 CALM1 PIK3AP1 CPA3 DUSP5 LRRC32 GPR84 PHF11 TNFAIP8 DIXDC1 TRAF1 PLGRKT NFKBIA ITCH NABP1 SPHK1 IRF2 CSF2RB SERPINE1 CLEC4E DCUN1D3 EYA3	down	***
GSE3982_CTRL_VS_LPS_4H_MAC_DN	0.0000010	0.0000174	0.6594444	-0.3590974	-1.902324	175	KMO SASH1 DENND5A USP12 CD55 LYVE1 BACH1 DDX6 CAV1 MYD88 ARL8B IL1RN IL23A CYB5A HIPK3 KLF6 NDEL1 BTG3 TUBB6 TIPARP EIF1B ROCK2 TBC1D9 BIRC2 CLIC4 ERP44 CCSER2 PLEK PIK3R5 MAFF TDRD7 HCAR3 DCP1A CD80 SAR1A NEK7 OASL CD48 MTMR9 RCAN1 IRF8 CREB1 ATP13A3 REL HIVEP2 RUNX3 MME CCR4 TFEB EWSR1 KCNA3 PDE4B PITPNA ABL2 NBN CEBPD LRP12 SP100 TRAF1 HNRNPC FAM13C SFPQ RAB2A PMAIP1 LYZ SPHK1 IRF2 SPSB1	down	***
GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN	0.0000003	0.0000061	0.6749629	-0.3587145	-1.902152	181	GPR17 SLC31A2 CXCL16 EDNRB HVCN1 SOWAHC U2AF1 RAPGEF2 PTPRE WDR74 ALAS1 BCL2A1 IL1RN FAM49A FGR PLXNA2 SDE2 KLF10 PTX3 SLC7A11 ABHD6 SRGN SPI1 PDGFA RAB12 PLAUR REST SOCS2 GPR85 IRAK2 ID2 CCL4 PNRC1 GCA SPRYD7 HCK PROCR NINJ1 SERTAD2 GPBP1 CD80 ETV3 PLK3 PPP1R15A IFRD1 PSTPIP2	down	***
GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN	0.0000046	0.0000684	0.6105269	0.4425407	1.899837	121	TFPI2 SLC16A14 NDC80 DEPDC1 TTK ANLN ECT2 CDC6 GAPDH FIGNL1 MCM4 BCL2L14 MCM8 NME1 RANBP1 HMMR EXO1 C9orf116 POLA2 MSX1 ICA1 SMYD2 RAD54L KIF11 C7orf50 KCNJ11 BLM TSHR PLA2R1 GEMIN4 EFCAB11 TNFRSF21 POLR3K REEP6 EIF6 DENND6B HMGN3 TRIM37 ESCO2 SYT1 CABLES2 LRRC59 MCM5 NMNAT1 TMEM198 ALG8 ESRRB SHCBP1 ACSF3 COX5B FAM118B MRPS27 COPZ2 MRPL20 ERRFI1 SLC1A7 NQO1	up	***
GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN	0.0000002	0.0000045	0.6901325	-0.3562490	-1.899795	182	ST3GAL6 ELF2 VAMP2 S1PR1 MAL LAMP1 TGFBR2 HEG1 TXNIP ASAH1 EIF1 BTG2 EIF5 LITAF SRGN PDE4D MCL1 CD37 EFCAB14 MOAP1 SDCBP LEPROTL1 TPP1 LAPTM5 RRP8 IL7R FOXN3 BTG1 RBM39 AREG NXF1 JUNB DUSP8 WTAP SP3 DDX5 THUMPD1 GPR183 HERC2P3 YWHAZ CLN3 SNRK MOB1A CDK17 CALM1 SRSF6 ZBTB1 HBP1 TOB1 RGS2 SPOCK2 PDE4B MBNL1 GTF2B CCDC69 CXCR4 EPHA4 ALDH2 BRWD1 IFFO1 CYTH1 DAZAP2 MT2A EIF4G2 ARHGEF18 CDC14A USP4	down	***
GSE7852_THYMUS_VS_FAT_TREG_DN	0.0000005	0.0000105	0.6594444	-0.3640856	-1.899704	168	MIR22HG INSIG1 STX11 TSHZ1 ABCB1 GINM1 ARSB ASAH1 GM2A ZDHHC2 ZNF503 FZD4 ADRB2 NDEL1 CYP4V2 TIPARP RHOB KDSR ARRB1 DUSP3 SORBS1 UHRF1BP1L DRAM1 CDKN1A NR1D2 PER1 ELMSAN1 GNAQ MAFF HGSNAT RBPJ ELF1 FAM189A2 WSCD2 IFNGR1 ENPP4 NPR1 FAM177A1 DENND4A SNX9 YPEL2 PKD2 PRKCG CCR4 IRF5 APBB1 PHF19 BMP2K IL18RAP YAF2 CEP170 ITPRIPL2 ARL14EP S100A4 EPB41L4A TNFSF9 SAMSN1 RORA MT2A ATF4 TRIM36 CBX7 PIM3 HERPUD1 JDP2	down	***
GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_UP	0.0000004	0.0000084	0.6749629	-0.3591169	-1.896996	174	MIR22HG LYL1 EGR2 PDE1B PLEKHF2 RCHY1 IER2 PDE2A STARD4 B3GNT5 EMILIN2 TMEM74B LITAF KLF10 TIPARP MAP2K3 FABP5 GAA USP2 MYO1B PLBD1 SPAG9 LAPTM5 LBH M6PR CD53 PER1 PLEK ELMSAN1 SH2D2A IL7R RPS6KA2 RBPJ MYO1C CABLES1 HIC1 FOXN2 PTGER4 KLHL18 GPR183 MALT1 REL RGS13 CST7 TPRA1 ATP6V0D1 FOSB CD74 TGFB1 PEA15 VPREB3 TSC22D1 NAB1 CD86 IRS2 RGS2 CCR6 LAT TOB2 UBE2D1 MMD FNBP1 CBX7 CYBA ATP6V0A1 EGR1	down	***
GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_UP	0.0000016	0.0000280	0.6435518	-0.3617780	-1.896638	163	RAB11FIP1 NLRC4 PPARG SOWAHC SNX10 CD44 PDE1B CAV1 IL23A CCNL1 RBM7 MCTP1 SBDS C16orf89 PPP1R15B MAP3K8 CRK PTPN12 RAB12 TNFSF15 VASP RMDN3 FBXL3 NFKB1 ATF3 IRAK2 PLEK GCA SPRYD7 KPNA3 FAM102B ETF1 SLC25A25 VPS37A PPP6C MITF CPEB4 FOXN2 PPP1R15A MALT1 PELI1 PTP4A1 MAPK8 TREX1 PIK3AP1 SORT1 EHD1 TMX3 SMCR8 CRY1 PLEKHO2 PDE4B ABL2 XKR8 NLRP3 NFKBIA MRPL32 TLK2 GSPT1 SPATA13 SLC16A10 UBAP1	down	***
GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP	0.0000017	0.0000291	0.6435518	0.4272423	1.895168	156	KIF20A CDC45 DEPTOR TROAP NEK2 UCHL1 TG KIF18B IGFBP6 AURKB LAMP5 PTTG1 TPX2 CCNB2 TYMS GLDC CDT1 MELK EXO1 MKI67 EMC9 TRIM29 TOP2A APOL1 E2F2 RRM2 RAD54L SEC61A1 KDELR2 IGKV1-5 ASS1 SCAMP5 COMMD4 WNT5B PSRC1 CDK1 NCAPG COL3A1 SPAG5 IGLV6-57 LMF1 TK1 DTYMK GINS2 IFNAR2 NOC2L MAT1A KDELR3 CDC20 DYNC1LI2 XRCC4 SSH3 HAX1 GINS3 DOLPP1 PDIA4 NT5DC2 CEACAM5 CEP85 B9D1 CCNA2 HDLBP ARSA GTF3C5 WDR76 IGLV3-19 UBE2C DHRS9 CALU CD38 BCKDK	up	***
GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_UP	0.0000025	0.0000409	0.6272567	-0.3640045	-1.895094	156	LPIN2 EGR2 C5AR1 CLEC10A FXYD2 NUDT9 C3orf70 MOB1B SPG21 NAAA SDE2 C1orf21 BTG2 PBX3 STOM TMEM38B CST3 ATP10A PTPRO CASP1 BST1 DRAM1 MARVELD1 TLR4 CD302 SLC6A6 CMTM6 PRCP SERTAD2 RBPJ OASL SERPINB8 C1QA RAC2 CCDC50 OSTM1 UBAC2 RNF24 SIGLEC1 RRAS MBP CD74 NUP153 KCTD10 IQSEC1 SP100 TRAF1 S100A4 TTC28 B3GNT2 SNAP29 MMD TMCC3 NRP2 NCF1 SLC38A2 FPR1 PLEKHA2 PLXDC2 NFAM1 PPWD1 PPIP5K2 SURF6	down	***
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP	0.0000010	0.0000183	0.6435518	-0.3565245	-1.893782	177	WEE1 CXCL3 RAMP3 SOWAHC IL1B TMEM170B CCRL2 ST3GAL6 HMGCR SLC15A3 VAPA HSPE1 EIF4A1 EIF1 MAP3K8 NLK PPP3CA FAM122A CSRNP1 C9orf72 ID2 ELK3 ELMSAN1 DSE MATK PPP2R5A PAFAH1B1 MAFF USP25 PRKRA IL6 RYBP SOCS3 RAB8B PPA2 LRCH1 MSRB3 ATP11A FOXN2 PPP1R15A GSTO1 FBXO11 ENPP4 PCGF5 TSPYL1 ATP6V0D1 EHD1 ZRANB1 TGIF1 CD86 IRS2 PPIG ADAM10 PDE4B ETS2 GEM ICAM1 NT5C2 IER5 IQSEC1 CXCR4 HNRNPK EPHA2 TRAF1 TMEM109 GPR171 ANXA11 LDLR ENY2	down	***
GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP	0.0000003	0.0000061	0.6749629	0.4205714	1.892522	179	HP KIF20A CDC45 MCM10 NEK2 UBE2T BRCA1 TTK IQGAP3 E2F8 ANLN ASPM CDCA8 AURKB CENPA ECT2 CDC6 CCNB2 TYMS PRC1 CCNF DTL SPDL1 CISD1 SMARCC1 KIF23 CHAF1A MKI67 BUB1 TOP2A AURKA KIF2C RRM2 KIF11 LMNB1 CDC25C LIG1 CHEK1 MAD2L1 RAD51AP1 PERP INCENP CKS1B CDKN2C NUSAP1 ASF1B CDK1 POLE2 UCK2 BIRC5 GMNN SUN1 DNA2 EZH2 CBX1 IFI27L2 DLGAP5 PSMA5 TACC3 KIF22 TK1 GALNT3 RHD DHRS1 CKAP5 CDC20	up	***
GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN	0.0000006	0.0000124	0.6594444	0.4216163	1.892145	172	TRIP13 BDH1 PAGR1 PDCD2L TPX2 RBBP8 CDC25A UMPS MYBL2 PRC1 APOL2 MELK DNPH1 EXO1 STAP2 EMC9 AUNIP AURKA POLA2 CDCA5 RAD54L CHAF1B B3GNTL1 ZNF443 CHEK1 TRMT2A BRIP1 BLM PPIL1 CKS1B TMEM106C EXOSC2 CENPJ UCK2 BIRC5 POLR3K NCAPG SMG9 PGBD2 MRPL17 SF3B3 RNASEH2A LZTR1 SNRNP25 PARS2 CCNE1 DNAJC17 RAD51D DTYMK ZNF239 JMJD4 LRWD1 RAD50 GEMIN6 PFAS CENPM FBXO22 PRMT1 GINS3 RCC1 ZNF780A CCNA2 SCO2 DCPS PDAP1 WDR77 TUBA4B ATOX1 RAD51 ZWILCH PFKM CDK5 LIF	up	***
GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP	0.0000005	0.0000099	0.6594444	-0.3573640	-1.887736	174	IL1A MIR22HG CCRL2 NEDD4L CDC42EP2 INPP5A NR3C1 IL23A ATP2B1 HBEGF MTF1 TNIP3 ANPEP KLF6 PTX3 HLX SERPINB9 SLC25A37 CD93 EPM2AIP1 MCL1 IL10 PTGIR PPP6R3 ZBTB43 CLK4 DNTTIP2 INHBA IL24 NINJ1 EMP3 PKIG HCAR3 DCP1A IL6 OASL NXF1 SERPINB8 STAT4 HRH1 PLK3 RHOG PPP1R15A FERMT2 CCR7 ENTPD4 TNFRSF9 HIVEP2 FOXO3 ING3 EHD1 SOD2 PDE4B ETS2 CCL20 ICAM1 TNFAIP8 NBN RIPK2 SIK3 NLRP3 TRAF1 OSER1 MAP3K4 NFKBIA CYTH1 DAZAP2 IL16 TRIM36 PMAIP1 SNW1 LAMP3 WNT5A MTSS1 ANKHD1 STARD5 NKTR DUSP22 CFLAR PTGS2 JARID2 IL32 AKAP13 KBTBD2 EBI3	down	***
GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP	0.0000007	0.0000129	0.6594444	0.4194331	1.885145	178	KIF20A FANCI BUB1B PBK TTF2 TBRG4 TOMM34 CENPA ESPL1 CCNB2 TYMS PRC1 SRPK1 ZWINT CDT1 NLE1 PON3 KIF15 KIF3B TOP2A PUS7 WDR3 TTLL12 CAD INPP4B MNAT1 SKP2 TMEM106C CDK1 POLE2 CEP97 UCK2 MCAT EZH2 POLR1C FGFR1OP KPNB1 EIF6 SNRNP25 MRPS34 LONP1 OSBPL3 TK1 DTYMK ANAPC1 MAGOHB MARCKSL1 YARS2 SUPT16H TIMM13 TSTA3 CENPM MYO5C STAMBP CKAP2 GINS3 STK39 SHCBP1 WDR77 RAD51 MRPL9 SMC2 DDX52 MTHFD1 PAICS UBE2C NCAPD3 TUBA1C PPP1R14B COX17 BRIX1 FBXL18 ERCC3 NCAPH F5 EIF2D AVEN POLRMT MRTO4 C12orf43 PTPRK MRPL12 CLPP HINT1	up	***
GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN	0.0000005	0.0000102	0.6594444	0.4167085	1.884146	187	TRIP13 PARPBP GMDS BUB1B DOC2A CCDC34 PBK GINS1 E2F8 PLK1 CDCA8 AURKB E2F3 CCNB2 FIGNL1 UHRF1 MCM4 TYMS PRC1 ORC1 DTL RANBP1 MELK EXO1 NUDT1 KNTC1 CDCA5 WDHD1 RAD54L LMNB1 CHEK1 ORC6 MAD2L1 GNPDA1 PPIL1 INCENP CKS1B CXCL14 RFWD3 NPM3 SLC25A13 SDCBP2 PSAT1 NEIL3 FEN1 DYNLL2 CCNE1 PSMA5 ALDH7A1 KIF22 COL5A2 TRIM37 TK1 CASP7 MLEC GINS2 SAP30 MAGOHB HLA-A CDC7 CLDN12 CDC20 FAF1 ASRGL1 DYNC1LI2 PRMT1 CKAP2 MCM5 RCC1 RAB34 CCNA2 PRIM1 RFC5 HK2 RAD51 ZWILCH SEC13 ARHGAP11A	up	***
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_DN	0.0000022	0.0000364	0.6272567	0.4257147	1.883793	151	HELLS CEP89 MCM10 NEK2 CENPF IGF2BP3 MPP6 DEPDC1B GINS1 RACGAP1 IQGAP3 E2F8 GMPS AURKB CDC6 TPX2 CCNB2 KNOP1 ORC1 MELK HMMR EXO1 KIF23 MKI67 KIF15 DPY19L1 MED12L SAE1 MPO RRM2 MRPL27 KIF11 CDC25C CCDC58 AHCY RAD51AP1 BRIP1 CXCL9 NCAPG2 RNPC3 CENPH BIRC5 NEIL3 SPAG5 GBP5 PA2G4 TUBG1 TACC3 ARL6IP4 LRWD1 GALNT3 ATAD5 COX10	up	***
GSE3982_DC_VS_TH2_UP	0.0000005	0.0000091	0.6749629	-0.3578235	-1.883513	170	GPD1 SMAD6 SLC31A2 TAL1 DCSTAMP THBD ENG LYL1 LMO2 C5AR1 CLEC10A SLC15A3 FUCA1 PILRA CD36 ANXA1 MAN2B1 CD33 SLC7A7 ABCG2 LITAF ANPEP PTX3 TNS1 ATP6V1H SETD3 CST3 CCL22 BST1 CPVL COQ10B UBTD1 MAP1LC3B ARNTL TPP1 TMBIM1 PDE8A CDKN1A MATK HLA-DQA1 CLN8 MITF HK3 CTSZ PPP1R15A CD83 PLCG2 FAM204A SORT1 CD1D TSC22D1 RGS2 PITPNA SESN1 PARM1 NLRP3 SLC2A9 ULK2 TMEM87A FAM13C C1orf115 CACNA2D3 UBAP1 CTSH	down	***
GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0000006	0.0000121	0.6594444	-0.3541657	-1.882996	180	CD300LF ST8SIA6 RDX GPR65 GIMAP8 HSD17B11 TMOD3 BACH1 GPCPD1 TET2 FAM49A RHOA B3GNT5 UBL3 MALAT1 GM2A ABCG1 CYB561A3 CLN5 SLC25A37 BTG3 EVI2B ITM2B KLF7 PLBD1 MGAT4A ELAC1 VIM EVI2A ADD1 AFF3 SNN TBC1D5 EMP3 MYLIP SGK1 KCTD12 RCAN1 CCR7 GPR183 FAM43A LPCAT2 KLF2 FOXO3 CD1D ATXN1 CD81 LGALS3 KYNU GPR18 SERINC3 CCR6 SELPLG CALHM2 ESYT1 CTSC FOXJ2 GIMAP4 RSU1 RNF13 ARHGEF18 FUS NCF1 KMT2E MAN1A1 MAP3K1 KLHDC1 TRIM25 CCPG1 JARID2 ST3GAL1 MFHAS1 ANXA6 RASSF5 MFSD8 CAPG DPP4 MYO1H ATP10D	down	***
GSE3982_EOSINOPHIL_VS_BCELL_DN	0.0000011	0.0000204	0.6435518	0.4200794	1.882412	167	FAT2 APOLD1 GBAP1 RACGAP1 E2F8 NIPSNAP1 UMPS GLDC MAP2K6 VILL SHMT2 AGK TOP2A LARS2 KLHDC4 MCM3 ACTL6A FBL PERP CAD SLC35E2B MRPS30 NAA40 CNPY2 TRIT1 ZNF32 CBX5 PPM1E AP3D1 NUP205 ETFB DNMT1 GOLGA3 FANCG CCNE1 TRADD OSBPL3 MYBBP1A CASP7 JMJD4 IL15RA ACAD10 AGPAT5 DAP3 IGHM ASNS DNMBP FN3KRP PLCH2 PFAS STOML2 MRPS33 MAB21L1 ABCD4 PRMT5 PMS2P1 FAM3C SMARCA4 SYBU ABCF2 MAP3K9 NDUFA8 INSL3 TCF3 PWP1 RRS1 IFI16 AKR7A2 KCNH4 DHX57 SLC38A10 UTP18 PSME1 PRPSAP2 TCFL5 PMVK	up	***
GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_DN	0.0000029	0.0000462	0.6272567	0.4201638	1.880124	166	C1GALT1 KIF20A MDM1 RUVBL1 CDC45 TICRR BUB1B CENPF PBK KIF18B NDC80 PRIM2 GINS1 CDCA2 AGFG2 RACGAP1 NUF2 CDCA8 CENPA ESPL1 TPX2 FIGNL1 PRC1 CCNF DTL HMMR EXO1 CEP55 MKI67 TOP2A AURKA KIF2C WDR78 RRM2 CDCA5 GPSM2 LIG1 MAD2L1 CKAP2L CBY1 SKP2 KNSTRN NUSAP1 ASF1B BIRC5 GMNN NCAPG EZH2 CENPP CHCHD3 CCNE1 ALDH7A1 MNS1 TUBB2A TK1 IGHM PLEKHB1 ATAD5	up	***
GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN	0.0000007	0.0000132	0.6594444	-0.3530969	-1.877313	180	CXCL3 EREG ACP5 IL1B MIR22HG ENG HEG1 GGA2 EIF4A1 ADA LMNA ANPEP RNASE1 PTX3 SLC7A11 LAIR1 SRSF2 FABP5 AHNAK HNRNPA3 ID3 DAB2 SLC7A8 VASP THBS1 CCL3 NFKB1 CCL4 ALOX5AP DNTTIP2 CD300C GNAQ IL7R TP53BP2 PI4K2A EMP3 RPS6KA2 SERTAD2 KANK1 TECR SAR1A OASL SERPINB8 SH3BP5 LTBP2 MAP4K4 PPP1R15A FERMT2 SNX2 PIK3R1 YWHAZ SLC3A2 CALM1 TIMP2 EWSR1 APLP2 LGALS3 PLEKHO2 CPQ ARRB2 TOB2 TRAF1 TMEM184B S100A4 DOCK10 DLST	down	***
GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP	0.0000009	0.0000163	0.6594444	0.4153376	1.876138	185	FOXM1 CENPF TSFM TTK GMPS NABP2 PLK1 ECT2 ESPL1 RBBP8 MCM2 RAD54B TYMS MYBL2 SHMT2 CDT1 SPDL1 RANBP1 MELK EXO1 KIF23 KIF15 PUS7 NUP155 KIF2C MCM7 RRM2 RBM28 PDCD5 LMNB1 MAD2L1 DSCC1 EHF CNPY2 SKP2 PABPN1 GMNN GOT2 TRAP1 MCAT ITPKA FEN1 EZH2 CHCHD3 KIF22 DTYMK PKP4 FHL2 TRAF3IP1 ELAC2 CDC7 RAD50 GEMIN6 TIMM13 CKAP5 CENPM FAF1 LRRC59 PELO THOC5 PRMT1 CKAP2 GINS3 IL12RB2 RCC1 STK39 KLHL7 GLO1 RFC5 PAXIP1 SMC2 NMT1 NCAPD3 TUBA1C RAD1 DNM1L PPP1R14B COX17 BRIX1 CORO1B C9orf40	up	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP	0.0000007	0.0000132	0.6594444	-0.3547286	-1.873815	174	CD300LF CD52 SASH1 DENND5A TAL1 HHEX PTPRE LPL LMO2 MYADM TGFBR2 PEAR1 ANXA1 CD33 ADAM17 ZNF503 BFAR PPP3CA IL18R1 TCF7L2 CYP4V2 PTPN12 EVI2B TACR2 ST3GAL2 STX3 PLBD1 ITIH5 ID2 TEF PLEK KLRD1 N4BP2L1 PRDM5 HLA-DQA1 HCK MYLIP RNF149 CTSS RGS18 RAB31 TYROBP GLIPR1 IRF8 PRKCE PTGER2 CD34 ACSL1 RHOQ PKD2 SPOP DDHD2 VAV3 TSC22D1 CD86 CD81 MEIS1 GEM IL18 IL18RAP	down	***
GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP	0.0000024	0.0000388	0.6272567	-0.3575413	-1.872365	157	SIDT2 BAIAP2 SLC15A3 NR3C1 GNPTAB CCNL1 SH2B3 PPP2R2A RGCC CLK1 ADARB1 CSRNP1 FOXO1 ZSWIM6 MAFG SPAG9 CCL3 NFKB1 ZBTB43 CLK4 FXYD7 SH2D2A BTG1 NINJ1 RNF149 ETV3 ARL5B PLK3 EPC1 DUSP8 CD83 PTGER2 MIR23B TNFRSF10B TINF2 PIM1 CLDND2 GABARAPL1 ICAM1 ABL2 USPL1 SIK3 BRWD1 TRAF1 ADORA2A JMJD1C TTC19 RORA MT2A ZFAND2A ATF4 RABGEF1 HERPUD1 CCNK CD69 SLC25A19 ZBTB46 FNIP1 NR4A3 HIVEP1 AKAP13 NFKBIZ DUSP2 FEM1C KANSL3 RASA2 ANKRD17 ITK BCL2L11 ABTB2 PPP1R16B SESN2 RARA ATG16L2 NFAT5 VPS37B RELB ELL2 TNFAIP3 DNAJB2 CMIP PAN3	down	***
GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN	0.0000007	0.0000127	0.6594444	-0.3530339	-1.872029	181	KLF13 ZC3H12C EGR2 FOSL1 HMGCR VAPA MOB1B IER2 SLC7A7 EIF1 PPP2R2A GATA3 NR4A1 SRGN BTG3 ATP6V1H IL10 MAP2K3 ROCK2 STAT5A SDCBP RNFT1 RMDN3 NFKB1 ATF3 CCL4 CCND2 SH2D2A ACTG2 BTG1 ETF1 METAP1 RNF149 IL6 NOTCH1 KCTD12 ST6GALNAC4 FYTTD1 IRF8 HSD17B12 AGFG1 FOS RHOQ PELI1 MSMO1 DDX18 PDCD1 GABARAPL1 CCR1 MAGOH CSNK2A2 RXRA FKBP1A CUL3 BCAT1 NFKBIA B3GNT2 GIMAP4 PIM3 EGR1 TNFSF8 DUSP6 FIP1L1 CENPC AQR BCL10 SLC25A19 IL5 TES FNDC3A SRXN1 TTC39B DUSP2 OTUD7B ARID3B GGNBP2 MTDH AGO2 DNAJB6 ZNF281 MAPK6 IQGAP2 PTPN1 ZC3H14 NFATC1 ZC3H11A CINP EIF2S1 NCOA3	down	***
GSE45837_WT_VS_GFI1_KO_PDC_DN	0.0000004	0.0000075	0.6749629	0.4171054	1.871064	173	UBE2Z NIPSNAP1 NDUFS6 SHMT2 NME1 NDUFB8 DNPH1 NUDT1 KCNN4 RFXANK SAE1 PDCD5 AHCY PSMD4 PFKP MRPS11 C7orf26 UQCR11 ZNF32 FASTK RBCK1 NPM3 TCF20 ETFB UCKL1 DDT MPI SNRNP25 MZT2A MZT2B TRADD MRPS34 HDHD3 ARF5 ARL6IP4 LAMTOR2 DAP3 COG4 AAMP COPS6 CCT7 YARS2 STOML2 ZNF428 CLASRP TBCA PRMT1 SRPK2 MCM5 CD2BP2 LSM7 NDUFS7 POLR2I EIF3K COPZ1 SNRPD2 PRPF31 ETHE1 UQCRQ GNA12 MPG MTHFD1 COX6B1 HEMK1 RANGRF MRPS16 DFFB PARL ADSL LCMT1 AP2B1 PLEKHJ1 SLC35C1 DDX49 GRHPR EBNA1BP2 XRCC6 TRAPPC2L DRAP1 PSMD8	up	***
GSE22886_DC_VS_MONOCYTE_DN	0.0000016	0.0000279	0.6435518	-0.3562140	-1.870178	167	FCN1 KLF13 CD55 U2AF1 PTP4A2 PID1 FYN HSD17B11 KIAA1109 INPP5A NEDD9 AGTPBP1 SLC11A1 LILRB3 IER2 SLC7A7 KLF6 CD93 TCF7L2 MCL1 CD37 GMEB1 MAP2K3 CFD CASP1 KLF4 P2RY2 SELL HPSE DUSP1 ELK3 GCA BTG1 CD48 CSTA FOS PELI1 KLF2 ICAM2 FAM204A ING3 CD1D IRS2 N4BP2L2 RGS2 CDC42EP3 CEBPD SIK3 SP100 MEGF9 CREBBP LYST THEMIS2 PMAIP1 DUSP6 CX3CR1 ING1 ITGAL FPR1 ZFP36	down	***
GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP	0.0000009	0.0000168	0.6594444	-0.3538375	-1.865665	173	SIDT2 LPXN BAIAP2 ZCCHC2 IDI1 HMGCR NEDD9 ZBTB2 ENTPD1 NAAA RNF125 KLF10 SERPINB9 PDE4D ZYG11B RHOB TJP1 CLIC4 FMNL3 CCL3 DOCK9 COTL1 ATF3 CCL4 PNRC1 SMAD7 ELMSAN1 SH2D2A SERTAD2 RBPJ SOCS3 JUN ARL5B HPGDS PLK3 IFNGR1 PPP1R15A PTGER4 SKIL MALT1 TINF2 PIK3AP1 CD86 PDCD1 TOB1 PDE4B ETS2 AMD1 GEM SF1 HSP90AA1 TOB2 HAVCR2 MEX3C NUP98 TMEM184B NFKBIA GPR171 TRIM36 PMAIP1 SLC16A10 HERPUD1 EGR1 DUSP6 SLC38A2 ZFP36 DNAJB4 QSOX1 CYP51A1 DNAJB1 TSC22D2 FNDC3A NFIL3 SIRT1 CASP3 GZMB DUSP2 ZFP1 ADAM19 TNFRSF1B	down	***
GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN	0.0000004	0.0000091	0.6749629	0.4154035	1.863429	173	SLC2A1 MUC16 CDCA7 POLE DGCR8 KCNQ5 CDC6 MCM2 XPO5 NME1 NLE1 KNTC1 PUS7 POLD2 AKAP1 ENTPD6 TARS2 SLC12A7 FAM162A LIG1 ABCB6 PFKP CAD PPP5C IDH2 PARP1 PES1 THOP1 E2F1 DNA2 PDK1 SMO SF3B3 UQCC2 DNMT1 PUS1 AARSD1 MC1R HIRA TRIM37 C9orf152 GBP6 GEMIN5 PKP4 SND1 PFAS UBE2O KIAA0100 RRP9 GPATCH4 TBCA LPCAT4 HEATR1 EXOSC5 DPH5 HDLBP PRPF31 HK2 HLCS RDH10 MRPL21 OSGEP POLR1B RPN1 DTNBP1 TRUB1 SYNE2 CISH RASGRP1 FAM185A IMMP2L HEMK1 AVEN ISYNA1 SRM TIMM10 NDRG1 LRP8 MTHFD2 COX6A1 PFKL IPO4 ABCC1 PUSL1 SLC29A1 TXNRD3 RPSA RAD51B	up	***
GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP	0.0000020	0.0000341	0.6272567	-0.3505915	-1.862267	177	MCOLN1 MIR22HG TRPV2 SMIM12 FLVCR2 GAS6 LAMP1 TRIB1 HEG1 CD36 RRAGC C1orf21 BTG2 TNIP3 ZNF410 HIPK3 HLX SERPINB9 STOM LAIR1 CRK PDGFA CASP5 RHOB COQ10B DRAM1 CDK9 MAFG RBMS1 FRMD4A CD53 DSE IL7R DCHS1 KREMEN1 SPIN1 SLC8A1 VPS37A CREM SOCS3 SLCO2B1 PLEKHA3 LRCH1 CPEB4 HK3 HRH1 VPS26A AGFG1 SNX9 PIK3AP1 JMJD6 KCTD10 FPR2 PIM1 GNA13 RIMKLB GPR18 SERTAD1 DCTN4 MS4A4A PLGRKT KATNA1 GRB10 NABP1 PSMD9 WDFY3 PUS3 SLC16A10	down	***
GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN	0.0000041	0.0000630	0.6105269	0.4148655	1.860671	168	RIBC2 CCDC34 CENPF GGCT SORD FGF11 EFNA4 UMPS PRC1 CCNF ACY1 KHDC1 C5orf34 RUVBL2 BZW2 EXO1 TP53BP1 PCCB WDR3 SYNE4 WDHD1 SDHAP1 KDELR2 BRIP1 FNTB INPP4B IDH2 CKLF MRPL37 CENPJ UCK2 WDR54 SMG9 TRAP1 KIF2A LRRC42 OARD1 ETFB MAD2L2 RECQL4 SNRNP25 PARS2 DNAJC17 FAH DNAJA3 HDAC1 ANP32E ATAD5 PARP9 NIF3L1 SASS6 NFXL1 FAF1 FAHD1 ROMO1 TDP1 HMCES LSM4 ZNF780A CEP152 RRNAD1 DCPS VDAC1 MICU1 CHMP2A PAICS PPP1R14B HEMK1 CORO1B ALKBH2 CYB5B C9orf40 BCKDK	up	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_UP	0.0000019	0.0000326	0.6272567	-0.3543723	-1.860509	167	IL1A USP12 OTUD1 NEDD4L AQP9 SFR1 BCL2A1 AGPAT4 SCARF1 RFTN1 SLC7A7 MTF1 TNIP3 PTX3 SLC25A37 AKT3 EIF1B IL10 TBC1D9 TNFSF15 SOCS2 SEC24B PDE8A P2RY2 ZBTB43 UBE2B HES1 TP53BP2 KANK1 FLT1 IL6 SOCS3 MAML2 STAT4 HRH1 WTAP ELOVL7 FERMT2 ENPP4 PNPLA8 SIGLEC15 FSD1L TNFRSF9 GFPT2 AGFG1 PIK3AP1 AZIN1 SAV1 EHD1 SERPINB1 FPR2 PIM1 ETS2 MIR155HG IER5 CDC42EP3 PLGRKT MAP3K4 BCAT1 NFKBIA RASSF8 PTEN MCOLN2 TRIM36 PAPSS2 SLC16A10 FJX1 SVIL DCUN1D3 OSGIN2 MSANTD3 YRDC HEY1 CCDC93 GPR137B	down	***
GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN	0.0000021	0.0000351	0.6272567	-0.3499166	-1.858682	177	CXCL3 IL1B SNX10 LPXN FIG4 C5AR1 CD9 IL1RN AGPAT4 CD5 LIFR RAP1A EMILIN2 LITAF HDC HIPK3 SIRPA TIPARP PTPN12 TBC1D9 DUSP3 AGO3 COQ10B TMED5 PDE8A ERP44 VIM ID2 DUSP1 AKIRIN1 RAB6A CD80 SNAP23 PLEKHA3 JUN RAB31 CTSZ PTGER4 STX7 PSTPIP2 PRKCG EMC7 AZIN1 NIPA2 ZC3H12D PIM1 ATXN1 ADPGK GEM YAF2 SLC31A1 NLRP3 ALDH2 MCOLN2 NRP2 NR3C2 NABP1 CSF2RB CLEC4E SLC38A2 FXYD5 MTSS1 NFIL3 ATF6 RC3H2 ECHDC3 CLVS1 PTGS2 ST3GAL1 CYTIP PSMD14 RNPS1 SCAMP1 NOP58 FGL2 ZNF281 PTPN1 BCAP29 S100A10 CCR5 EIF2S1 RILPL2	down	***
GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN	0.0000079	0.0001122	0.5933255	-0.3557070	-1.858404	154	CD300LF FAM167A ABHD5 MS4A7 PDLIM2 ZC3H12C RUNDC3B S1PR1 RXFP1 CD9 EDEM1 CD36 DNAJC3 GM2A CYB561A3 LAIR1 C1orf162 SIRPA GRN PDE4D HERC3 FBXL5 TBC1D9 SPNS3 ST3GAL2 PLBD1 LY96 PDE8A MGAT4A UBE2E2 RUFY3 RASGEF1B HCK BCAR3 UTRN HCST TYROBP ACKR3 RALB NDST1 ZC3H12D ATXN1 CD81 MICU3 BMP2K PIP4K2A RPS13 PLGRKT CTSC DOCK10 NRP2	down	***
GSE25677_MPL_VS_R848_STIM_BCELL_DN	0.0000046	0.0000691	0.6105269	-0.3540104	-1.855916	163	CD55 LMO2 SAMHD1 MYADM IER2 PDE2A B3GNT5 RAB33B PICALM KLF6 SLAIN2 PPP3CA AKT3 ITSN2 FLI1 ROCK2 FOXO1 LAPTM5 VIM SELL LBH GNAI2 CALM2 FAM76B ADD1 LMBRD1 AFF3 MTPN MYLIP FRY WASF2 STAT4 SH3BP5 JAK1 SNX2 IRF8 GMFG RAB8A TRAK2 SNX9 XYLT1 CC2D2B VPREB3 TEC ZCCHC10 IFNAR1 GNA13 PDE4B BRWD1 SSH2 SREBF2 IQGAP1 EHD4 CNN2 IRF2 ARHGEF18 ATP6V0A1 KMT2E PLEKHA2 TUBA1A ATP1B1 CSNK1G3 PIK3CG TRIM25 FCHSD2 ANKRD44 FAM107B RDH12 RFC1 CYTIP RASGRP3 SLAMF1 AIDA GTF2A1 PGAP1 TMEM64 SYNJ1 MED13 S100A10 BPTF LSP1 MAPK11 ARHGAP25 JAK2 RASGRP2 DMXL1	down	***
GSE22935_WT_VS_MYD88_KO_MACROPHAGE_UP	0.0000013	0.0000225	0.6435518	-0.3486467	-1.853653	180	FAM167A HVCN1 DCSTAMP TRPV2 PPP4R1 SAMHD1 SLC15A3 STX11 MARCO NCF2 GNPTAB LAMP1 CBL IGSF6 PILRA PDCL EDEM1 ANXA1 PLA2G7 ASAH1 EMILIN2 ITGA5 IFI30 LITAF TMEM123 CD37 SDCBP MEFV TPP1 ITGAX HPSE M6PR FCER1G ELK3 HCK NCKAP1L CD80 PGD RAB8B CD48 C1QA TYROBP SKIL GLIPR1 PTGER2 RAB8A SNX1 LPCAT2 AP3B1 MOB1A MFSD10 TMX3 DOK3 TGIF1 TGFB1I1 CCR1 SLC43A2 SELPLG	down	***
GSE3982_BASOPHIL_VS_TH1_DN	0.0000016	0.0000276	0.6435518	0.4125164	1.853154	171	HELLS ELOVL6 CHEK2 BUB1B NEK2 GGCT DDIT4 NUDCD3 TTC26 ALDH18A1 XRCC2 GLB1L2 MIS18A NME1 IKBKE RANBP1 SYTL2 AURKA SFI1 RSRC1 GCAT CHAF1B MORC2 CHEK1 DNAJC9 CC2D1A OGFOD2 BLM MTG1 PHB SPRY1 TMED3 PSMB5 CCNJL SPAG5 HMGXB3 PSMC4 UBFD1 TUBG1 DHODH MRPL11 DPH2 MRPL4 LRRC20 SCNN1G LIMA1 HMGA1 RRP9 CDR2 RAI14 STK39 CBR1 TCERG1 PRMT5 MSH2 SLC2A5 DCPS DOHH ABCF2 ELOVL4 RAD51 ZWILCH PPFIA3 ADRM1 CHL1 MTHFD1 PAICS ENO1 WIZ RANGRF NQO1 MLLT11 MRTO4 SHQ1 PRPF19 RWDD2B TOMM40 RPS6KB2 NETO2 STXBP1 MRC2	up	***
GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN	0.0000008	0.0000158	0.6594444	-0.3481526	-1.852828	184	ACP5 SC5D CTSW VAMP2 MAL LAMP1 TGFBR2 HEG1 TXNIP ATP2B1 EIF1 BTG2 LITAF HNRNPDL MCL1 CD37 SORBS3 CCNI MOAP1 SDCBP LEPROTL1 TPP1 SPAG9 LAPTM5 RBMS1 PER1 RNF139 PLCD1 NCOA1 FOXN3 BTG1 RBM39 AREG SGK1 NXF1 WTAP DDX5 HERC2P3 SNRK MOB1A CALM1 SRSF6 ZBTB1 FCGRT TOB1 RGS2 PDE4B TPT1 CXCR4 IFFO1 RPS13 OSER1 ICAM3 CYTH1 DAZAP2 MT2A SFPQ	down	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP	0.0000024	0.0000398	0.6272567	-0.3487044	-1.852243	177	CD300LF SASH1 DENND5A TAL1 OSBPL1A ST6GALNAC3 RAMP2 CD44 LMO2 SAMHD1 MYADM AQP9 ESAM S1PR1 MAN2B1 B3GNT5 CD33 PCYOX1 PPP3CA SIRPA IL18R1 PTPN12 ARRB1 CASP1 ST3GAL2 GRK5 SOCS5 MPL ITIH5 PER2 NR1D2 VIM CD302 PLEK KLRD1 NRROS PRCP CTSS MITF RAB31 IRF8 CD7 OGFRL1 CD34 SNX9 ITGA9 TSC22D1 CD86 CD81 MEIS1 RNF2 GEM ICAM1 CPQ PIP4K2A ARHGAP18 CCR9 PAIP2 THEMIS2 HEBP1 GRB10 MT2A	down	***
GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP	0.0000017	0.0000293	0.6435518	0.4121478	1.852207	176	TRIP13 ELOVL6 CHEK2 NEK2 PSPH TTK RACGAP1 ANLN ASPM CDCA8 PTTG1 CDC6 CCNB2 EIF3B DTL CDT1 NUDT1 CISD1 MKI67 BUB1 TOP2A AURKA POLD2 MCM7 CPD RGL1 CDCA5 PDCD5 MRPL27 KIF11 LMNB1 LIG1 KDELR2 CHEK1 ORC6 MAD2L1 BLM CKS1B DRC1 NUSAP1 CBX5 ASF1B CDK1 UCK2 BIRC5 POLR3K SEC61G SSX2IP NRGN DLGAP5 TACC3 DTYMK ZNF239 GEMIN5 CENPK SASS6 DHRS1 PSMB3 CDC20 MRPL41 MRPL51 NEDD8 MARCKS UNC119B RPS26 DCPS ECH1 MIEN1 RFC5 PRPF31 SEC13	up	***
GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN	0.0000012	0.0000207	0.6435518	-0.3489536	-1.851897	176	EREG KMO SC5D IL1A TUBD1 OSBPL11 SOWAHC ZC3H12C IL1B CCRL2 TMEM138 HEG1 ADAM17 SWT1 ITGA5 SIRPA MOB3C NFE2L2 CES1 BTG3 PDGFA TUBB6 ATP6V1B2 CD58 PTPN12 ST3GAL2 DAB2 STX3 MYO1B UXS1 PLEKHB2 KBTBD4 PAFAH1B1 PIK3R5 CRIM1 INO80C GABARAPL2 PSEN1 CRNKL1 PDCD6IP SERPINB8 DNAJA1 GSTO1 TPRA1 HIVEP2 MSMO1 BTBD7 TSC22D1 KYNU ANKRD12 ITPRIPL2 HSPA8 KIF1B CAMSAP2 CREG1 LINC00884 RNF13 ARFGAP3 MED31 PIM3 FADS3 ITGB1 ZFYVE1 EYA3 YRDC CYP51A1	down	***
GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP	0.0000010	0.0000179	0.6435518	-0.3517369	-1.851474	170	KMO ARHGAP31 SC5D IL1A MCOLN1 ZC3H12C IL1B CCRL2 FLVCR2 TMEM138 CD22 HPS5 PLA2G7 LACTB RRAGC ADAM17 ITGA5 SERINC1 CLN5 MOB3C NFE2L2 LAMTOR3 CES1 BTG3 PDGFA TUBB6 CD58 ST3GAL2 DAB2 STX3 MYO1B NFKB1 RIT1 IRAK2 PLEKHB2 PIK3R5 MMP19 PSEN1 CRNKL1 PDCD6IP SERPINB8 DNAJA1 GSTO1 PNPLA8 TINF2 SNX9 MSMO1 BTBD7 TSC22D1 EWSR1 CD81 KYNU WDR1 ITPRIPL2 SEC61B HSPA8 STAM2 FNIP2 KIF1B NABP1 CREG1 ARFGAP3 CYBA HMGCS1 OSGIN2 ZFYVE1 EYA3	down	***
GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN	0.0000052	0.0000781	0.6105269	-0.3530872	-1.851076	163	CD300LF SGK3 OSBPL11 LIPA TRPV2 HSD17B11 LY86 S1PR1 MEF2A ANAPC15 MAN2B1 RRAGC UBL3 CLEC7A RNF144B ABCG1 TTYH2 STOM ARL11 APOC1 ATP6V1B2 ATP10A AHNAK EPOR KIAA0513 CEBPA LAPTM5 COTL1 ATF3 ATP6V0D2 VWF HEXB MYLIP CTSS PHACTR2 SLCO2B1 HPGDS VAT1 ADRA1A TYROBP IRF8 MIR23B MBP MSMO1 XYLT1 DCK ATP6V1A APLP2 RGS2 PLA2G15 GPX3 IQSEC1 LRP12 HAVCR2 TMEM184B SKI CYTH1 MMD ZFAND2A RNH1 CNR2 HMGCS1 CX3CR1 CD109 PTGS1 HEY1	down	***
GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN	0.0000006	0.0000124	0.6594444	0.4124157	1.850026	173	TRIP13 KLC3 HELLS MCM10 NDC80 POLE CDCA8 ECT2 CDC6 E2F3 MCM4 RUNDC3A MCM8 MELK EXO1 TP53BP1 KNTC1 TOP2A IFI44L CENPW CLSPN WDR78 RRM2 MMS22L CDCA5 AKAP1 RAD54L SOX4 SALL2 LIG1 CHEK1 MAD2L1 CKAP2L DSCC1 PTGFRN BLM PML CKS1B NCAPG2 PLOD2 ASF1B PAK1 CDK1 BIRC5 GMNN E2F1 EZH2 CNOT11 RTP4 CENPP HSPA4L IFI27L2 ATP9A LMF1 TK1 ATAD5 PARP9 CENPK GTF3C1 CENPM DNMT3A MCM5 ALMS1 PRR11 SHCBP1 ZWILCH SMC2 ENTPD7 ADCY6 RNF213 SMPD4 CHL1	up	***
GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN	0.0000024	0.0000389	0.6272567	-0.3522587	-1.849972	164	LPIN2 ABHD5 SNX10 TTC7B CD44 CTSW MYADM AQP9 GNPTAB FAM49A ZEB2 PDE2A ANXA1 ATP2B1 ENTPD1 ZDHHC2 LAIR1 IL18R1 PPP3CC AHNAK CASP1 PLEKHM3 FAM49B CTSD ITGAX VIM HOPX ATP6V0D2 ID2 PRF1 DSTN UNC5A IL7R PIK3R5 CALM2 CNOT6L HCST CAPN11 CCDC50 IFNGR1 PTGER4 EEA1 DAPK2 TBX21 CST7 NKG7 KLRC2 SMPDL3B CHPT1 GSAP ATXN1 POLK IL18RAP ARHGAP18 S100A4 KLRK1 RORA GIMAP4 TNFSF8 UBA6 ITGAL ITGB1 ARL4D S1PR5 ATP2B4 RPA2 DOCK5 CD226 IMPACT TTC39B MYO1F KLRC1 MYO5A ADAM19 TNFRSF1B F2RL2 SLAMF7 GZMK SOS2	down	***
GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	0.0000010	0.0000179	0.6435518	0.4121573	1.849932	177	RUVBL1 CDC45 TICRR MCM10 TIMELESS POLQ BRCA1 ASPM AURKB EBF3 MCM2 CCNF EIF3B MCM8 MIS18A NCAPD2 CCDC150 CHAF1A TRIM29 KNTC1 POLA2 COASY TTLL12 CDCA5 DNAJC9 TIMM50 DSCC1 BLM PSRC1 NCAPG2 NUSAP1 MRPL37 SERTAD4 CENPJ ATIC RBCK1 UNG FEN1 EZH2 SPAG5 SF3B3 RECQL4 KPNB1 POLR2H SNRNP25 MRPS34 UBE3D DOK4 DTYMK TJAP1 ANAPC1 NUP85 RBM33 CPSF4 CDC20 LRRC59 MGME1 MCM5 MALSU1 DDX23 SLC1A5 STK39 CORO2A PMS1 GLO1 PRR11 CISD3 CCDC167 WDR4	up	***
GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP	0.0000017	0.0000287	0.6435518	-0.3540962	-1.847582	168	CXCL3 IL1A GLIPR2 CPEB2 IL1B RAPGEF2 HCAR2 CCRL2 GFOD1 RASAL2 SLC15A3 STX11 ALAS1 IL1RL1 IL1RN TET2 TNIP3 MAP3K8 PICALM HDC FOXP1 SLC7A11 SLC25A37 IL10 UHRF1BP1L CLIC4 CCL3 NFKB1 CXCL2 C9orf72 CCL4 DUSP1 PLEK OXSR1 IL7R PIK3R5 HTRA4 PROCR FMNL2 RNF149 IL6 SOCS3 INPP5B OASL TREM1 ELOVL7 MALT1 TNFRSF9 PTP4A1 HIVEP2 RIN2 SMPDL3B PIM1 SOD2 STK40 GNA13 PDE4B IER5 RIPK2 RND1 NFKBIA EDN1 MCOLN2 TNFSF9 SAMSN1 NRG1 MT2A	down	***
GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN	0.0000009	0.0000168	0.6594444	-0.3477161	-1.845557	178	WEE1 DENND5A LRRC8C SNX10 CLDND1 TTC7B CD44 CTSW ST3GAL6 AQP9 CYB5R3 BCL2A1 FRAT1 FGR ANXA1 KLF10 KLF6 PRSS12 GATA3 IL18R1 CRTAM TXN PPP3CC AHNAK CASP1 YBX3 KLF4 CTSD ITGAX HOPX ID2 CCL4 RECK PRF1 MBD2 SH2D2A N4BP1 MAPRE2 CD160 GABARAPL2 SLC35E4 GSTO1 EEA1 DAPK2 CD7 DYM CST7 FOS KRTCAP2 FOSB CHPT1 PIM1 TOB1 JUND RNF138 IL18RAP	down	***
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN	0.0000033	0.0000520	0.6272567	-0.3520734	-1.844844	165	SGK3 EGR2 BMPR2 YPEL5 BCL2A1 AGPAT4 TEX2 WWC2 UBL3 BTG2 LUZP1 FOXP1 TRAF6 CRK CRTAM ZFYVE16 EFCAB14 LEPROTL1 MGAT4A CCL4 TEF CCSER2 SH3BP5-AS1 PPP2R5C CLIP4 IL7R RUFY3 AKIRIN1 VAMP3 MN1 PIK3R1 HERC1 RC3H1 ENTPD4 HOMER1 GFPT2 ASTE1 FOS TRAPPC10 ZRANB1 BAZ2B TSC22D1 ZBTB11 MIA3 MAP3K2 RIMKLB PDE4B ARAP2 PDLIM5 IL18RAP SERTAD1 EPHA4 PSME4 SOAT1 KLRK1 RORA EHD3 ZBTB40 ZBTB44 RABGEF1 VPS13D DKK3 FAM53B TSC22D2 ATP8A1 SNRPN SETD2 TMEM170A NR4A3 DUSP2 USP33 ZCCHC14	down	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN	0.0000013	0.0000237	0.6435518	-0.3489216	-1.843140	174	ACP5 FCN1 CD101 HHEX FABP4 LTA4H FBP1 LIPA TMEM170B SAMHD1 MKNK1 CD9 FUCA1 GGA2 AVPI1 TXNIP CD36 NCEH1 TACC1 CLEC7A ZNF503 REV3L RNASE1 ABHD6 C1orf162 EVI2B TIMM10B PPT1 KIAA0513 MARVELD1 EVI2A RAP1GDS1 MPC1 UBASH3B CD300LB PRCP RBPJ RBP7 SLCO2B1 GLUD1 LPCAT2 VMO1 GAS2L3 FOS SORT1 VAV3 GALC MFNG PLA2G15 CALHM2 ARHGAP18 S100A4 METTL7A CD1E DOCK10 RHOT1 DISP1 C5AR2 CRTAP CCDC112 TREM2 DRAM2 PLXDC2 FPR3 MPV17 RCBTB2 SKAP2 SMIM4 CHKA WDFY2	down	***
GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN	0.0000016	0.0000274	0.6435518	0.4087426	1.839293	179	TRIP13 FOXM1 KCNK5 CDC45 FANCI CENPF TIMELESS POLQ GGCT BRCA1 TTK NDUFS6 PTTG1 ESPL1 CCNB2 TRIB3 KNOP1 TYMS ALDOC SHMT2 COQ3 TOP2A AURKA TMEM177 RRM2 FSD1 GPSM2 MCM3 DCTPP1 MRPS11 BLM CDK1 POLE2 BIRC5 PLA2G2A GMNN NCAPG SEC61G KIF2A RTCB RNASEH2A EIF6 CHCHD2 UQCRFS1 DLGAP5 GSS MRPS34 PTGES2 SSRP1	up	***
GSE6259_CD4_TCELL_VS_CD8_TCELL_DN	0.0000042	0.0000641	0.6105269	-0.3510165	-1.837869	160	SLC31A2 LPIN2 PPP4R1 DYRK1A TET2 SLC11A1 RFTN1 ARHGAP10 IFI30 STOM C1orf162 LAMTOR3 IL10 ITM2B ATP6V1D ATL3 CDS2 ATP6V0D2 FRMD4A CD300C DSE PEAK1 IL7R HTRA4 CD300LB SNN USP25 PRCP ARHGAP17 RNF149 BCAR3 SNAP23 PDCD6IP CD48 HPGDS RAB31 PDE5A GPR141 JAK1 STX7 CAP1 RIN2 PIK3AP1 GSAP DOK3 SMCR8 ZC3H12D STX12 KAT2B ICAM1 MOB3B CTTNBP2NL TIAM1 NUP98 KLRK1 FNIP2 THEMIS2 DOCK4 EHD4 IRF2	down	***
GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP	0.0000060	0.0000880	0.6105269	-0.3536604	-1.834383	151	SLC31A2 MS4A7 FBP1 TUBB1 EGR2 SAMHD1 STX11 RXFP1 LAMP1 ASAH1 CHMP1B NAAA LITAF PRSS12 STOM C1orf162 GPBAR1 TCF7L2 CST3 RHOB ZFAND5 ATF3 PLEK KLRD1 MBD2 VAMP5 INSL6 CALM2 CMTM6 FAM102B SRGAP2C ARL6IP5 CREBRF FMNL2 SCEL IL6 RGS18 GLUD1 RHOG IQSEC3 SUCNR1 MOB1A AGPS ALDH3B1 PIK3AP1 NPTN ARPC2 CDKN1C CALCOCO2 S100A4 COMMD8 CTSC PDE4A FNIP2	down	***
GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN	0.0000021	0.0000345	0.6272567	0.4065885	1.833495	181	TRIP13 PSPH PRIM2 BRCA1 METTL1 ANLN NDUFS6 IFT27 ACAD9 ALDH18A1 MCM2 CCT6A XPOT TAMM41 NUDT1 CISD1 KIF23 MKI67 TOP2A POLD2 LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD PHB CNPY2 CKS1B MRPL37 CDK1 BIRC5 CCT3 GMNN POLR3K MRPL17 TSPAN31 NOP2 TPD52L2 TUBG1 TACC3 MNS1 TRIM37 DUSP12 NUP85 RAD50 CENPK CKAP5 CDC20 RRP9 LRRC59 RPL7L1 CKAP2 MCM5 HAX1 NEURL4 RCC1 PDIA4 HAUS4 GADD45G RFC5 PDAP1 WDR77 INO80E HK2 PGAM1 SPR RPN1 POLR1A DDX52 CHERP DTD2 CYB5B RCN2 MRTO4 SRM PLK4 HRAS MRPL2 COQ5 GCSH ABCD3 PPA1 TIMM9 CRCP MTHFD2	up	***
GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000040	0.0000607	0.6105269	-0.3500746	-1.832736	162	EPAS1 PHACTR1 PECAM1 CD55 LRRFIP1 COQ2 GFOD1 RTN3 MEF2A BCL2A1 FUCA1 TGFBR2 TRIB1 GGA2 SERINC1 IL18R1 RAB14 ATP6V1B2 ZMIZ1 SDCBP PTAFR ZCCHC24 THBS1 ERP44 CXCL2 CD302 UBE2B SLC6A6 GNAQ RSL24D1 SNN MED28 CTSS PSEN1 PGD CRNKL1 PIKFYVE DAPK2 RPS6KA1 DENND4A RALB TINF2 ACSL1 FOS BTBD7 SORT1 OSGIN1 PIK3C3 RXRA SELPLG RLF CYB5R4 TBC1D1 ACACB OSER1 DAPK1 THEMIS2 CREG1 SFPQ PPP1CB DCUN1D2 RABGEF1 HAT1	down	***
GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP	0.0000018	0.0000309	0.6435518	-0.3451295	-1.830115	181	FAM167A FYN CCRL2 NEDD4L RTN3 PRKAR1A GIMAP6 RFTN1 CCNL1 DNASE1L3 PDE2A KIAA0355 EIF5 MAP3K8 LITAF BFAR NFE2L2 KDSR STK17B GAPVD1 NR1D2 M6PR ELMSAN1 GNAQ NUS1 USP16 BTG1 NINJ1 ARHGAP17 RYBP SGK1 RBM34 CPEB4 ST6GALNAC4 FOXN2 EPC1 TBC1D12 BAG5 ATXN1L IFRD1 GMFG GPR183 ATP6V0D1 CD164 AZI2 CD74 AZIN1 PEA15 VPREB3 CDC37L1 IRS2 RELL1 STK40 RNF2 RLF SFT2D1 RIPK2 PLGRKT RBM48 LYSMD3 MAFK CYTH1 ZFAND2A BANK1 FNBP1 CNR2 MZT1 OSGIN2 SLC26A11 CSNK1G3 PTDSS1 GPR137B SERP1 FCHSD2 MAPK7 KCTD18 C15orf48 EIF4E3 CBFB RANBP2 WHAMM CCNT1 GNL2 FEM1C TANK EZR MAT2A FGL2 EXOC5 PDS5A CMTM7	down	***
GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP	0.0000111	0.0001505	0.5933255	0.4088045	1.829294	166	GRIA4 KCNK5 MCM10 GMDS FBXW8 TG BRCA1 DEPDC1B GINS1 CDCA2 CDK4 IQGAP3 ANLN POLE SNF8 ASPM NUF2 ECT2 GPI GRIN2A FIGNL1 DTL MIS18A KIF23 EME1 SAE1 RAB19 IFT43 CLSPN PASK BRI3BP DNAJC9 CKAP2L PFKP RAD51AP1 ABCB9 MRPS11 CAD GNPDA1 THOP1 KNSTRN KIF2A ETFB DDT SNRNP25 TACC3 AARSD1 TRIM37 LRWD1 FBXO44 ORMDL2 AAAS	up	***
GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN	0.0000022	0.0000366	0.6272567	-0.3440858	-1.828013	179	CXCL3 LPIN2 ADPRH SOWAHC ZC3H12C FABP4 FYN RGS9 BAIAP2 MYD88 NUDT9 LMNA ANXA5 LITAF HDC FOXP1 SERPINB9 NDEL1 TIPARP MAP2K3 PTGIR RAB12 NPNT STX3 CDKN1A M6PR SLC6A6 ETF1 CD80 EBF2 ESD RAB8B STAT4 PTGER4 IFRD1 PIK3R1 CD83 SLC3A2 HIVEP2 EHD1 TGIF1 KCTD10 TEC ATP6V1A ATP6V0C GABARAPL1 GNA13 TSPO IST1 FKBP1A SF1 NBN SLC25A20 TRAF1 ULK2 NFKBIA ADORA2A MAFK CYTH1 TNFSF9 RORA LDLR	down	***
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN	0.0000016	0.0000274	0.6435518	-0.3443876	-1.827891	178	EPAS1 LPIN2 LPXN GPR65 PLEKHA1 S1PR1 NEDD9 FUCA1 ATF7IP2 ABCB1 IER2 SH2B3 SLC7A7 CACNA2D2 TMEM204 KLF10 SERPINB9 TOR1AIP1 SPTBN1 CRTAM PDGFA ADARB1 PTPN12 FOXO1 LEPROTL1 ID3 COTL1 PTPRC LBH CD53 SMAD7 EVI2A PPP2R5A DCHS1 ARL6IP5 SGK1 IL2RB INPP5B RAB8B RAC2 JAK1 CCR7 GPR183 RASSF2 HIVEP2 CD6 DOK2 SPOCK2 PDE4B PHLPP2 GIMAP5 PTCH1 G3BP2 ULK2 CAMSAP2 GRB10 GIMAP4 IL16 EHD4 MAN1C1 SMPD1 HNRNPH1 EGR1 PRKCH ICOS	down	***
GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN	0.0000033	0.0000517	0.6272567	0.4061814	1.825585	178	TRIP13 CDC45 MCM10 ELOVL6 GGCT PBK CDK4 CDC6 SFXN1 RBBP8 MCM4 MCM2 PRC1 ORC1 DTL CCT6A SHMT2 XPOT MRPS35 CDT1 CCT2 NME1 RANBP1 MRPL15 EEF1E1 CCT5 POLD2 MCM7 CPD TOPBP1 DNAJC9 MAD2L1 RAD51AP1 DCTPP1 BLM CKS1B GMNN POLR3K PSMB5 MRPL17 FEN1 NUP205 PSMC4 PA2G4 POLR2H DNMT1 VBP1 DPP3 TUBG1 LMNB2 MLEC GINS2 ASNS POLD1 CCT7 CDC20 STOML2 BCL2L1 MCM6 MCM5	up	***
GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_DN	0.0000026	0.0000415	0.6272567	-0.3463231	-1.825532	172	CXCL3 SLC31A2 ZMYND15 SWAP70 ZC3H12C PID1 SLC6A12 CAV1 MYD88 STX11 ALAS1 MARCO IGSF6 PILRA PDE2A KCNAB1 ANXA1 PLA2G7 NDUFAF1 MAP3K8 SPI1 TFRC MCL1 SYNPO KCNMA1 VASP NFKB1 GSDMA CD302 N4BP1 PIK3R5 TLL1 ARHGDIB GLB1 HCK RBPJ SRSF3 SERPINB8 MTMR14 LIMD1 CTSZ HSPA1B JUNB PTGER4 MOB1A CD74 SMPDL3B TGFB1 EHD1 GSAP FPR2 IFNAR1 GPR84 SOD2 GPR18 PDE4B ICAM1 PDLIM5	down	***
GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000017	0.0000291	0.6435518	-0.3436872	-1.824173	178	CXCL16 OLR1 DENND5A PTP4A2 GPR65 INSIG1 NEDD9 BCL2A1 HPS5 EDEM1 B3GNT5 SLC36A4 LATS2 BZW1 KLF10 TMEM41B SRGN TFRC TIPARP DIABLO ZMIZ1 MAP2K3 PLAUR SPAG9 NFKB1 CDKN1A GGTLC1 SIK2 ADIPOR2 OXSR1 PIK3R5 MAFF SNN NINJ1 RBPJ GZF1 ETV3 STAT4 CD83 ENTPD4 ATP13A3 SLC3A2 CDK17 RUNX3 AZIN1 ZBTB1 GPR84 SOD2 NBEAL1 ZNF267 PDE4B CCNH ICAM1 RLF IER5 RAB5A ZBTB25 TXNDC11 G3BP2 NFKBIA SAMSN1 DOCK4 DNAJA2 SPHK1 AFTPH	down	***
GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN	0.0000018	0.0000309	0.6435518	0.4060850	1.822677	177	CDC45 FANCI NEK2 CCNB1 GGCT SORD PHGDH TTK GINS1 NIPSNAP1 AURKB CDC6 TPX2 MCM4 ORC1 CCT6A MYL6B CDT1 NME1 CHAF1A MKI67 PCCB EEF1E1 TOP2A POLD2 KIF2C WDHD1 RAD54L PKM CDC25C AIMP2 IDH2 MNAT1 PARP1 THOP1 TMEM106C CDK1 HDGF NPM3 UNG TRAP1 FADD ETFB SRD5A1 DNMT1 CCNE1 DLGAP5 FAH GALK2 PSMA5 SNRPA LMNB2 SSRP1 FHL2 PFAS CKAP5 AHCYL1 STAMBP MCM5 AP2S1 PYCR1 PRIM1 GBP1 ECHS1 CPOX ETHE1 VDAC3 OSGEP PCBD1 MRPS27 BCAT2 ENO1 RAD1	up	***
GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_UP	0.0000056	0.0000829	0.6105269	-0.3439393	-1.822024	175	EPAS1 PDLIM2 ASGR1 OSBPL11 PECAM1 OSBPL1A CAT THBD LYL1 SAMHD1 FCER1A RTN3 SLC25A30 IL1RN TGFBR2 SYNC CD36 DPEP2 SPG21 RNF125 TMEM38B EVI2B PPT1 SDCBP CASP1 KLF4 DAB2 TPP1 PAPSS1 CD302 SFTPD SS18L2 PINK1 WFS1 LMBRD1 HEXB ARHGAP17 PRKRA TECR CYB5R1 SH3BP5 RAB31 KCTD12 TMEM251 GMFG PTGER2 MBP VAV3 DECR1 CLEC2B CCNH RXRA MOB3B PCM1 CPQ CCDC69 ALDH6A1 GPD1L S100A4 ARPC5 CCND3 EMC3 RNF13	down	***
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN	0.0000026	0.0000417	0.6272567	-0.3428647	-1.821526	179	SASH1 USP12 OTUD1 LMO2 BACH1 NEDD4L AQP9 SFR1 BCL2A1 IL23A TNFRSF8 SLC7A7 MTF1 C1orf21 TNIP3 KLF6 PTX3 HLX SLC25A37 TFRC CASP5 IL10 SAP30BP REST FBXL3 PDE8A ATL3 P2RY2 CXCL2 IL7R HES1 TP53BP2 IL24 KANK1 HCAR3 FLT1 IL6 SOCS3 PIKFYVE ETV3 STAT4 MAP4K4 WTAP FERMT2 ENPP4 PNPLA8 SIGLEC15 FSD1L GTDC1 GFPT2 AGFG1 PELI1 SLC22A1 PIK3AP1 SERPINB1 FPR2 PIM1 ANKLE2 TNFAIP8 MIR155HG MGAT2 IER5 CDC42EP3 TRAF1 RND1 PLGRKT MAP3K4 PTEN B3GNT2 THRAP3 SAMSN1 TRIM36 PAPSS2 CSF2 SLC16A10 FJX1 SVIL HMGCS1	down	***
GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN	0.0000042	0.0000636	0.6105269	-0.3426179	-1.819913	177	NLRC4 SLC31A2 MS4A7 PHACTR1 SOWAHC FABP4 CAT P2RY1 TMEM170B CAPN14 CITED2 AQP9 MYD88 SLC15A3 DNAJB14 CD36 STARD4 ADAM17 PPP1R15B CYB5A C1orf162 ITPRIP COQ10B KLF11 STK17B TLR4 DUSP1 ELK3 SLC6A6 OXSR1 IL7R BCLAF1 SMNDC1 DEGS1 BTG1 PDK4 CD80 RAB8B FOXN2 GSTO1 PTGER2 HSD17B12 GTDC1 CAP1 TOM1L2 FOS DDHD2 KCNA3 PDLIM5 MIR155HG CEP170 OPN3 NBN TFPI RTN4 CEBPD MEGF9 MMD THEMIS2 EIF4G2 CHML DCUN1D3 CMPK1 DRAM2 HEY1 MFSD1 GABPB1 SERP1 NMI	down	***
GSE25677_MPL_VS_R848_STIM_BCELL_UP	0.0000086	0.0001206	0.5933255	-0.3490410	-1.819512	155	CD300LF ABHD5 PDLIM2 ZC3H12C PGC RUNDC3B PLEKHA1 S1PR1 RXFP1 CD9 FUCA1 EDEM1 CD36 PLA2G7 GM2A MS4A14 MS4A1 LAIR1 C1orf162 GRN PDE4D HERC3 PER3 TBC1D9 PLBD1 FMNL3 PDE8A UBE2E2 ID2 UXS1 CARS2 DSE MATK RUFY3 RASGEF1B HCK BCAR3 UTRN TYROBP ACKR3 LPCAT2 NDST1 TCF4 NAB1 CD86 ATXN1 CD81 CCR1	down	***
GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN	0.0000044	0.0000657	0.6105269	-0.3464343	-1.819384	164	LPIN2 SWAP70 SNX10 CD44 MYADM SFR1 GNPTAB ZEB2 ANXA1 ARHGAP10 ARSB ENTPD1 ZDHHC2 SERPINB9 LAIR1 NR4A1 IL18R1 MPHOSPH6 SRGN BAG1 AHNAK CASP1 YBX3 CLIC4 CCL3 ITGAX HOPX ID2 CCL4 PRF1 PLEK DSTN INSL6 CALM2 CD80 CD48 CCDC50 IFNGR1 DAPK2 COBLL1 TBX21 TIGIT SLC25A24 NKG7 KLRC2 PIK3AP1 SMPDL3B CHPT1 GSAP DUSP5 ATXN1 GABARAPL1 PHF11 NPTN GEM IL18RAP	down	***
GSE30083_SP3_VS_SP4_THYMOCYTE_UP	0.0000142	0.0001848	0.5933255	0.4111005	1.819381	154	TFPI2 KCNMB2 ABCC2 MEX3A COL27A1 TOX3 TUBB2B GINS1 TTC26 CHRNA7 BCL2L14 GRHL3 LDHB KIF23 RND2 CBLC CBX3 SSPO ABCC5 TEKT2 TMEM45A ADM2 DUSP23 TRIM11 WDR60 ARMC12 PKMYT1 IPO9 SLC45A3 PLOD2 CROCC CCDC61 ABHD17C TNK2 CTXN1 TTC23L SMO TMEM120B CBX1 SPEF1 ALDH7A1 JMJD4 TJAP1 EDARADD CCDC159 DHTKD1 ABCC9 VWA3B NMNAT1 FFAR2 MARCKS ANK3 ZNF286A FLRT1 CAPN10 TCTEX1D1 SOX12 F13A1 CTTN PTPRF CHL1 ZNF354B PTOV1 BFSP2	up	***
GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN	0.0000059	0.0000864	0.6105269	-0.3471785	-1.819195	165	KMO SIDT2 SWAP70 HHEX SIK1 FIG4 LY86 CORO1C MEF2A CD1C CD22 FAM49A FGR GGA2 SLC7A7 GM2A MAP3K8 IFI30 MS4A1 GNG7 GRN TUBB6 CD37 TBC1D9 PIP5K1B YBX3 DENND3 CLIC4 HLA-DQA1 HCK PRCP SNX3 PKIG RAB31 STX7 IRF8 GRB2 COBLL1 IGKV3-20 CDK14 PLCG2 RHOQ CD74 TFEB TCF4 CD1D VPREB3 PDLIM1 CBFA2T3 CD86 KYNU TAGLN OPN3 SPIB ITGAE SCPEP1 METTL7A CD19 EHD3 BANK1 CSF2RB CTSH BHLHE41	down	***
GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000200	0.0002482	0.5756103	0.4127609	1.818901	144	KRT5 XYLB PBK CDCA2 ESPL1 CCNB2 KNOP1 MCM2 CCNF PVT1 NME1 RANBP1 DNPH1 EXO1 C19orf48 MKI67 ANO7 EME1 CDCA5 RAD54L PDZK1IP1 AHCY PFKP DCTPP1 SNAPC4 PPP5C THOP1 NCAPG2 NUP205 RAB11FIP4 MYO19 C19orf44 SSRP1 KCNC3 MYBBP1A MFSD2A AGPAT5 NRF1 POLD1 ELAC2 RAD50 CHPF CDC20 CENPM RRP9 NOB1 LSM4 NEFH PYCR1 PRIM1 RTEL1 MRPL55 PDAP1 WDR4 NUBP2	up	***
GSE9988_LPS_VS_LOW_LPS_MONOCYTE_DN	0.0000411	0.0004547	0.5573322	0.4255962	1.818380	119	RIBC2 BBOX1 HS3ST1 FAM182B PAX9 SLFN13 MYO3B SOX2 PAGR1 RHOV CATSPERB STIL KRT16 CDC6 GRHL3 GRB7 ASXL3 GSDMB KIF15 C20orf197 BPHL AURKA GPR182 MYRFL ZYG11A NOL3 ATAD3C ARL16 PRRT3 ISOC2 KIF19 UQCC2 LINC00173 GAL3ST4 LGR5 TMTC2 RGS7BP ZBTB7B BCDIN3D-AS1 STAG3L4 SKAP1 TMEM254 SHCBP1 BMP8B TNKS1BP1 PPP6R2 PNKP MPG ANKS6 FRZB MUC1 ISLR ZNF740 NOS3 MORN3 PPARGC1B PNPO LGR4	up	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN	0.0000016	0.0000276	0.6435518	0.4053551	1.818353	173	EGLN3 BDH1 CCDC34 PIF1 PTTG1 GPI PRC1 ACY1 RUVBL2 HLTF TP53BP1 AURKA WDR3 POLD2 TMEM45A WDHD1 KISS1R CDC25C SALL2 SARS2 THYN1 SPC24 BRIP1 OGFOD2 FNTB COMMD4 IDH2 PSRC1 CASP6 CKS1B C12orf75 MEA1 TMEM106C CENPJ UCK2 WDR54 GOT2 TRAP1 MRPL17 KIF2A FEN1 EZH2 LRRC42 SAPCD2 ETFB IGSF3 POLR2H SNRNP25 DNAJC17 FAH OSBPL3 RAD51D DTYMK FAF1 MCM5 TDP1 TMUB1 HAUS4 LSM4 TXNL4A ZNF780A CEP152 PRIM1 ELOVL4 ATOX1 ZWILCH POP4 SEPHS1 PCBD1 BCAT2 MRPS26 CORO1B C9orf40	up	***
GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000124	0.0001642	0.5933255	0.4097009	1.817187	155	KIF18B NDC80 DEPDC1 TTK CDCA2 RACGAP1 GTSE1 KIF14 ANLN STIL NUF2 CDCA8 AURKB ECT2 TPX2 FIGNL1 PRC1 ALDOC DTL ITGA2 HMMR KIF23 PON3 MKI67 KIF15 KNTC1 BUB1 TOP2A E2F2 CLSPN DPCD CDCA5 RAD54L KIF11 CDC25C MAD2L1 CKAP2L GPX8 CDKN2C ASF1B CDK1 BIRC5 PLCH1 KCTD13 NEIL3 SPAG5 SEMA4F HSPA4L DLGAP5 TACC3 KIF22 ARL6IP4 CASP7 ESCO2 HID1 SPAG1 GALNT3 POLD1 TRAF3IP1	up	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN	0.0000028	0.0000455	0.6272567	0.4042516	1.815600	175	CCDC34 ASPM FLAD1 TTC26 EFNA4 TPX2 ACY1 CCT6A SRPK1 RUVBL2 DNPH1 NLE1 WDR3 POLA2 WDHD1 CHAF1B LMNB1 THYN1 ACTL6A RAD51AP1 TIMM50 BRIP1 OGFOD2 CKLF PPIL1 CKS1B MEA1 TMEM106C CENPJ BIRC5 GOT2 FEN1 EZH2 FADD LRRC42 OARD1 SF3B3 ETFB RNASEH2A SNRNP25 COA3 DNAJA3 SLC37A4 MRPL52 TK1 DTYMK ZNF239 ASNS SAP30 SND1 NIF3L1 VPS25 CENPM STOML2 MRPS33 MCM5 TDP1 LSM4 ZNF780A SUV39H2 CCNA2 PRIM1 DCPS ATOX1 ZWILCH GBP2 CDK5 MTHFD1 PAICS ZC3HAV1L TPRN ZNF367 PPP1R14B FTSJ3 RPP25 MRPL12 GSTP1 CLPP PSMB10 RNF8 DCLRE1B HDDC3 ARMC6 RMI1 TIPIN NUDCD1 ORC5 CCDC124 CTPS1 TMEM14A PSMD8 MPLKIP	up	***
GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN	0.0000028	0.0000455	0.6272567	0.4042073	1.815401	175	PCSK6 TRIP13 CDC45 FANCI BUB1B CENPF PBK PIF1 BRCA1 DEPDC1B E2F8 SLC27A2 ANLN SPP1 CDCA8 KNOP1 SMPDL3A XDH NCAPD2 CDT1 KIF23 STAG3 MKI67 SLFN5 KNTC1 TOP2A SAE1 MCM7 TPCN1 RRM2 TTLL12 CDCA5 WDHD1 CCDC89 SBK1 KIF11 GPR146 SEC61A1 LIG1 HES6 PKMYT1 SLC25A10 PSRC1 INCENP CKS1B TMEM106C ANAPC5 KCNE3 SPAG5 CENPP QPRT CEP192 KIF22 ARL6IP4 HIP1R POLD1 CDC7 CENPM ARHGAP22 CENPT CEP152 CKAP4 PRIM1 CDH1 PRR11 SHCBP1 ZWILCH RNF213 CENPE POLR1A CDC25B NELFA ZBP1 NLRC5 NCAPH	up	***
GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_UP	0.0000743	0.0007684	0.5384341	0.4356484	1.814420	100	KIF1A KIF12 RIBC2 KLC3 PTPRT SPATA24 MYBPH PPP1R1B PAX9 DCST1 WFDC2 CHST4 SDK2 DIO2 SLC4A8 LAMC2 PCDHGB7 WDR72 LINC00265 PROM2 OXER1 GRHL2 C9orf163 PPIC PANX2 OVOL3 SEC16B S100A16 TTLL10 FTCD MADCAM1 ACOT11 VWA3A CCDC60 CNTN2 ELFN2 MEP1B ARHGEF39 TRIM67 FAM78B UBTF AQP4-AS1 KCNH4 ZNF740	up	***
GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN	0.0000144	0.0001861	0.5933255	0.4045149	1.814249	168	HJURP FBXW8 SLFN13 NEK2 MND1 PHGDH GINS1 CDK4 ANLN PLK1 CENPA MYBL2 PRC1 GJB7 AACS LIME1 ZWINT GOLPH3L CLPTM1L TMEM41A GOLPH3 KIF23 MKI67 TOP2A E2F2 PLXNA1 MAD2L1 AHCY TMED3 MRPL37 CDK1 GMNN PSMB5 SDR42E1 SEC61G RNF181 PSMC4 UBN2 GOLGA3 TUBG1 DLGAP5 PSMA5 MRPS34 PSME2 TMEM237 ASNS SIL1 KDELR3 STOML2 AAAS CLINT1 PRMT1 TMEM147 NDUFS7 KATNB1 MRPL51 CCNG1 CEP152 CCNA2 ECH1 BMP8B RDH10 ADRM1 PAICS GOLGA2	up	***
GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000063	0.0000912	0.6105269	-0.3423742	-1.813733	175	OLR1 DENND5A CLDND1 TBC1D2 HPS5 TRIB1 ZEB2 PTS SLC36A4 PPP1R15B BZW1 GPBP1L1 NR4A1 NFE2L2 LAMTOR3 HNRNPU RNFT1 MAP1LC3B SPAG9 GGTLC1 CXCL2 IRAK2 PNRC1 ADIPOR2 OXSR1 FKBP15 SNX3 RBPJ PPIL4 ETF1 RYBP GABARAPL2 RAB8B ARL5B SH3BP5 NSMCE2 PTGER4 HSPA13 OSM MALT1 TPRA1 SLC3A2 AKIRIN2 NDUFA5 ADPGK CRY1 RXRA ICAM1 TTC21A NUP98 G3BP2 GLUL NFKBIA EDN1 ZDHHC5 DNAJB9 ANXA11 RABGEF1 SERPINE1 HMGCS1 ATF2 ING1 CCNK ZNF654 CD69 CCDC93	down	***
GSE27786_CD4_TCELL_VS_NKCELL_DN	0.0000029	0.0000465	0.6272567	-0.3413924	-1.813704	179	SNX10 MIR22HG APIP MSRA MKNK1 TET2 HPS5 SCARA3 GGA2 KIAA0355 NFIX ARSB C1orf21 MAP3K8 PICALM ADIPOR1 TOR1AIP1 SPRY2 CRTAM TMEM38B EPB41L2 LRP4 PTPN12 BNIP2 ITM2B PLEKHM3 TMED5 FMNL3 PTPRC CTBS PAPSS1 TM6SF1 PRF1 KLRD1 PPP2R5A SLC6A6 TM9SF2 HES1 HEXB CDC40 SNAP23 OASL ARL6IP6 LIMD1 ATP6V0B VPS26A UBAC2 SMU1 MBNL2 FAM43A ATL2 REL YWHAZ ATG3 RIN2 TFEB CRYZL1 GEM CPQ ITPRIPL2 RTN1 TOB2 ITCH NABP1 MAPKAP1 NIPSNAP3A CYBA UBAP1 PHYH FHL5 CHML CMPK1 ARL4D FAR1 YWHAB	down	***
GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP	0.0000092	0.0001280	0.5933255	-0.3440919	-1.810993	169	IL1A SIK1 EGR2 CCRL2 FLVCR2 ESAM WWC2 PTPRM HBEGF LATS2 BTG2 CYYR1 NR4A1 TNS1 CD93 SPRY2 PDE4D CSRNP1 TSPAN12 PLAUR FAM76A ID3 OSTF1 THBS1 CXCL2 ATF3 UXS1 PER1 DUSP1 MAFF RASGEF1B FOXN3 SLC25A33 SLC25A25 CREM SGK1 SLCO2B1 JUN OXNAD1 ARL5B PLK3 JUNB RCAN1 PPP1R15A ACKR3 HOMER1 CD151 FOS SPRY4 FOSB ZFYVE9 DUSP5 TGFB1I1 ADPGK SLC10A6 ETS2 GEM CEBPD DAPK1 EDN1 TMCC3 JDP2 KALRN EGR1 SERPINE1 DUSP6 NR4A2 ARL4D ZFP36 VSTM4 ANGPT2 ADHFE1 AKAP12 TNFSF18 TRIM25 NR4A3 PTGS2 NTF3 RNF19B	down	***
GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN	0.0000039	0.0000594	0.6105269	-0.3435126	-1.810717	172	CLIC3 DENND5A OSBPL1A CD55 HHEX MNDA SIK1 FXYD2 DNASE1L3 ZEB2 SH2B3 MAN2B1 GM2A LITAF CD93 GRN TFEC TPP1 LY96 CD302 FCER1G ALOX5AP GLB1 ARHGAP17 KANK1 CTSS UTRN STAT4 KCTD12 ST6GALNAC4 TYROBP PPP1R15A STX7 GLIPR1 IRF8 GPR183 MFAP4 RPS6KA1 TNFSF13 FOSB CD74 TCF4 PEA15 MILR1 SERPINB1 BAZ2B ACYP2 RGS2 OPN3 IQSEC1 SPIB MS4A4A ALDH2 GPD1L TMEM184B CTSC DUSP7 THEMIS2 RSU1 FEZ2 HERPUD1 CSF2RB CTSH	down	***
GSE19512_NAUTRAL_VS_INDUCED_TREG_DN	0.0000087	0.0001221	0.5933255	-0.3458904	-1.809715	153	SIRPB1 RBP4 EPAS1 EREG NOVA2 ABHD5 OLR1 DENND5A FCN3 LPXN PTPRE INSIG1 PPP4R1 NR3C1 CD5 PBX3 SERPINB9 CRTAM CD58 KIAA0513 CASP1 GCHFR CCL3 NPAS3 CXCL2 CCL4 UBE2B ELK3 RAP1GDS1 GNAQ HEXB RBPJ FLT1 LRRTM2 PSEN1 IL2RB KCTD12 BMP3 GSTO1 PABPC4 REL CD7 TNFRSF10B SLC25A24 NAPG	down	***
GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP	0.0000034	0.0000534	0.6272567	-0.3430007	-1.808526	173	EPAS1 PECAM1 RBMS2 GIMAP8 TRPV2 SH2D3C IDI1 NUDT9 MKNK1 TMX4 RBM7 KLHL30 B3GNT5 HBEGF ARSB C1orf21 PBX3 PAQR3 SERPINB9 HERC3 BAG1 CD37 ZYG11B RHOB EIF1B ZADH2 FAM49B RIT1 COTL1 CTBS PTGER3 TM6SF1 ANXA3 ADD1 MYLIP TECR AREG ASNSD1 EBAG9	down	***
GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP	0.0000056	0.0000831	0.6105269	-0.3449535	-1.808469	171	SEMA6B EREG PID1 BCL2A1 SLC11A1 ATP2B1 CARD16 MCTP1 SIRPB2 ASAH1 SWT1 CAMTA1 SLAIN2 TOR1AIP1 TCF7L2 TMEM38B FBXL5 PTPN12 AGO3 PPP6R3 LIMS1 BST1 PLAUR DAB2 MAFG LAPTM5 ARAP3 TM6SF1 ALOX5AP PINK1 FKBP15 IL24 MAPRE2 KREMEN1 CNRIP1 STK24 FLT1 DDX60L KIF13A PDCD6IP SERPINB8 SH3BP5 MED30 CARD8 TMEM251 PNPLA8 YWHAZ SNX9 RUNX3 MYL12A VAV3 TGIF1 TSC22D1 CCL20 BNIP3L ATP9B C7orf31 BCAT1 RAB2B DAZAP2 CHIC2 DUSP6 LINC00922 SLC19A2 PRKCH ICOS SH3GLB1 SLC38A2 YRDC	down	***
GSE3982_BASOPHIL_VS_NKCELL_UP	0.0000082	0.0001162	0.5933255	-0.3450492	-1.808038	165	KRT81 EREG OSBPL11 LYL1 BACH1 MYD88 NTM MANBA ANXA1 WWC2 NDUFAF1 NLK SPTBN1 UBE2D3 MCL1 FLI1 FBXL5 SDCBP KIAA0513 FAM124B UHRF1BP1L TM6SF1 TM9SF2 ACTR2 RAB6A BTG1 ZCWPW1 AREG BCAR3 PPP6C RAB31 GSTO1 LYRM1 YWHAZ NDUFV2 PTP4A1 NOP10 RBKS MARC2 AZIN1 CHPT1 MIA3 CNOT7 PIM1 UTP3 CCR1 ADAM10 SERINC3 PDLIM5 TNFAIP8 LMOD1 TPT1 LRP12 CYB5R4 ESYT1 NLRP3 GLUL MARC1 C21orf91 DAZAP2 GRB10 EID1 SVIL CRBN OSGIN2 TREM2 SH3GLB1 ZNF654	down	***
GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP	0.0000032	0.0000506	0.6272567	-0.3399034	-1.807167	180	LYL1 LY86 LDB2 MYADM FUT1 ADCYAP1R1 DYRK1A MKNK1 NCF2 ANAPC15 CD22 GGA2 SLC44A2 SH2B3 UBL3 TM2D3 IFI30 MS4A1 NDEL1 SPI1 MCL1 RAB14 CCL22 SELL EPS15 PER1 WFS1 HLA-DQA1 HCK PKIG ASNSD1 PHTF2 CTSS LIMD1 KCTD12 PLK3 SNX2 IRF8 RALB PLCG2 SNX9 RHOQ HIVEP2 CD74 IRF5 TCF4 TEC CBFA2T3 NFYC CD81 WBP2 KANSL2 SERINC3 PITPNA BMP2K CCR6 ZNF143 SPIB CD19 IQGAP1 EIF4A2 EIF4G2 CTSH CFL2 CNR2	down	***
GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN	0.0000122	0.0001634	0.5933255	-0.3462077	-1.804742	155	TMEM170B CD44 HMCN2 TMOD3 CALCRL CDC42EP2 SLC15A3 NR3C1 SCARF1 CCNL1 ANXA1 TNIP3 MAP3K8 COX18 FOXP1 KLF6 CLN5 MTHFR CSRNP1 CASP1 LIMS1 PTAFR PLAUR VASP KLF7 FBXL3 NFKB1 IRAK2 SELL PNRC1 PIK3R5 KREMEN1 TDRD7 USP25 MITF CCDC50 PI4K2B PCGF5 RC3H1 SYPL2 KCNA3 KAT2B RNF2 XKR8 ALDH1B1 EDN1 TLK2 TNFSF9 AIM2 MIER3 IRF2	down	***
GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_UP	0.0000193	0.0002423	0.5756103	0.4109504	1.804423	141	LTF TRIP13 CDC45 BRCA1 LCN2 TTK KIF14 POLE PLK1 NUF2 CDCA8 CENPA ECT2 TPX2 PRC1 NUDT1 TOP2A CLSPN KIF11 CHAF1B LIG1 CHEK1 DNAJC9 MAD2L1 SPC24 INCENP CKS1B NCAPG2 CBX5 CDK1 CENPH BIRC5 JAKMIP1 NCAPG NEIL3 DLGAP5 TACC3 KIF22 HDAC1 ANP32E IGHM PPP1R8 RPA1 GMPPA MCM6 CD2BP2 SUOX CCNA2 RAD51 COX5B ARHGAP11A UQCRQ RPN1 SEPHS1 TTC9C PIGQ TRPC4AP ACSL5 COPE PLAC8 PRRC1	up	***
GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN	0.0000017	0.0000291	0.6435518	-0.3405927	-1.804398	186	IL1A SOWAHC GLIPR2 IL1B SNX10 MYADM MYD88 PLEKHA1 BCL2A1 IL1RN IER2 TRA2B MAP3K8 ZEB1 SRGN UBE2D3 PDGFA RHOB IL10 MSR1 STAT5A RAB12 PLAUR VASP NFKB1 CDKN1A CXCL2 SELP CCND2 CD53 DUSP1 N4BP1 KPNA3 PROCR RNF149 SOCS3 INPP5B MTMR14 MAP4K4 JUNB IFRD1 ATP13A3 ACSL1 AGFG1 GPR3 RHOQ PELI1 YTHDF3 PBRM1 EHD1 NAB1 IFNAR1 PIM1 STK40 LTBP1 ETS2 IST1 ICAM1 SLC31A1 SERTAD1 CEBPD HSP90AA1 HNRNPK SRSF10 MCOLN2 TNFSF9 SPATA13 HNRNPH1 HERPUD1 SERPINE1 CLEC4E PIAS2 KCMF1 TES DLD FNDC3A PDPN PTGS2 HIVEP1 JARID2 NFKBIZ RNF19B	down	***
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN	0.0000040	0.0000608	0.6105269	-0.3392996	-1.802586	179	CXCL3 EREG IL1A HMOX1 ZCCHC2 CCNL1 DNASE1L3 HSPE1 CLCF1 PTS ADA PICALM ANPEP RNASE1 ZFYVE16 UBE2D3 PTPN12 MAP2K3 HNRNPA3 PLAUR SNIP1 CDS2 ZBTB43 CD53 DNTTIP2 MARK3 NCOA1 MMP19 TDRD7 NINJ1 PSEN1 CD48 DUOX1 OSTM1 PPP1R15A PTGER4 PSTPIP2 GRB2 ATP13A3 OGFRL1 CLN3 ACSL1 CALM1 YTHDF3 FOXO3 ICAM2 ITGA9 PHF11 MFSD12 IL18RAP ABL2 CEBPD LRP12 RIPK2 NLRP3 SP100 G3BP2 DOCK4 SFPQ WDFY3 DNAJB5 SPHK1 SPSB1 C1QB	down	***
GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN	0.0000114	0.0001540	0.5933255	-0.3420208	-1.800093	169	HMOX1 LRRC8C DCSTAMP BACH1 CORO1C BAIAP2 SLC25A30 FXYD2 STX11 NCF2 CD9 AGPAT4 ACER3 AVPI1 ANXA1 STARD4 SPG21 PICALM LUZP1 LITAF KLF6 SLC7A11 TMEM123 ATP6V1H TBC1D9 ITPRIP SDCBP VIM HPSE ACTR3 ALOX5AP UBASH3B HLA-DQA1 CMTM6 ZDHHC20 SOCS3 RAB8B HCST CD48 C1QA RAB31 PLK3 SKIL PTGER2 MALT1 ZCCHC9 TMEM128 MOB1A RUNX3 PKD2 CD86 CCR1 PITPNA TNFAIP8 ARPC2 ELOVL1 PIP4K2A RIPK2 SOAT1 ANKRD49 NFKBIA	down	***
GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN	0.0000081	0.0001143	0.5933255	0.4043858	1.799537	161	CA9 CDCA7 FLAD1 ALDH18A1 SPATS2 COCH GLDC MIS18A ZWINT UQCC1 CLPTM1L RPAP1 KIF3B IGLV1-44 MCM7 RRM2 MCM3 SEC61A1 MCCC2 KDELR2 ZKSCAN1 BLM MRPL37 PKD1P1 TCTN2 POU5F1B MRPS12 METTL3 TRAPPC12 ZNF692 PABPC1L GNPAT PDCD11 IGLV6-57 SLC26A2 MAMSTR CCT7 KLHDC3 MRPL24 MED24 PIGU HAX1 PDIA4 PPP1R3E PMS1 HDLBP ECH1 TYSND1 AURKAIP1 UQCRQ MTHFD1 IGLV3-19 SETD5 TFB1M CD38 APEH MRTO4 NSUN5 DGUOK MAP3K12 ALG6 HDDC3 CYSLTR2 MEN1 SLC44A1 OIP5 HM13 NSUN5P1 C11orf24 NVL DDB1 FKBP2 ST6GAL1 METTL5 NDUFB10	up	***
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP	0.0000153	0.0001965	0.5756103	-0.3470644	-1.799268	146	SLPI SECISBP2L CD55 LRRC8C ST6GALNAC3 FYN PLEKHA1 NEDD9 ZBTB2 ZEB2 LATS2 UNC45B CASP1 AIRN CCND2 DUSP1 GCA N4BP2L1 VAMP5 ZDHHC20 RPL17 TBC1D5 FRY NSMAF PHACTR2 PRAP1 DDX17 JUNB DAPK2 CD7 CST7 KLF2 FOXO3 NKG7 GIMAP1 ADPRM AKIRIN2 VAV3 BAZ2B TEC RGS2 SYT11 GEM RBL2 SERTAD1 SP100 ULK2 CD3G THEMIS2 TOX2 IRF2 PHYH CX3CR1 ING1 S1PR5 EP300 CD3E CCPG1 DOCK5 CD226 CCNC NIPAL3	down	***
GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP	0.0000035	0.0000537	0.6272567	-0.3387720	-1.797863	176	FCN1 CD101 OLR1 LTA4H LPXN PTP4A2 MIR22HG CLDND1 PID1 BACH1 ST3GAL6 AQP9 CYB5R3 RBM14 HMGCR CD5 MTF1 ANXA5 REV3L SLC7A11 SRSF2 IL18R1 SLC25A37 PDE4D CD58 HNRNPA3 CASP1 THBS1 ARAP3 CD53 BTG1 FRY PGD PSMA1 DDX17 MAP4K4 TREM1 RHOG IFNGR1 CCR7 GLIPR1 IDS CDK2AP2 CST7 GRIK1 MOB1A SLC3A2 FOS HNRNPA2B1 TPMT KYNU PITPNA JUND ITGAE HNRNPK TRAF1 ENY2 DNAJB5 ZBTB44 PPP1CB C5AR2 DUSP6 TMEM43 PRKCH GPR153 FPR1 BBS7 A4GALT GNG11 FPR3 LAMP3	down	***
GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP	0.0000028	0.0000455	0.6272567	-0.3384342	-1.796292	178	SIDT2 ST8SIA6 KLF13 SPNS1 LIPA IL1RL1 ZBTB2 PDE2A CHMP1B BTG2 FOXP1 PPP3CA TMEM123 BTG3 ADAMTSL4 ZYG11B CCNI PPM1K STK17B SELL PNRC1 CCND2 CD53 PIK3C2A SMAD7 MBD2 UBASH3B DEGS1 AFF3 NRROS CD8B CREBRF S1PR4 ELF1 UTRN ETV3 JUN LIMD1 NXPE3 UBAC2 GMFG OSM IDNK TNFRSF9 RNF146 PLCG2 PELI1 CD164 TGIF1 PDLIM1 MFNG EIF3F IL18RAP LAT TAB2 SSH2 S100A4 PTEN LPAR6 GIMAP4 EHD3 EGR1 CDKN1B FAM8A1 KBTBD11 SNX14 KIDINS220 STX16 RNF111 TRIM25 SLC25A45 MAT2B AKAP13 KLRC1 ANKH FBXO33 CRLF3	down	***
GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000029	0.0000465	0.6272567	-0.3383191	-1.795681	178	SLPI DENND5A GPR65 RAPGEF2 PTPRE LRRFIP1 FOSL1 ZCCHC2 CDC42EP2 SLC15A3 AGTPBP1 RRAGC ANPEP KLF6 ADIPOR1 SIRPA TCF7L2 CD37 ATP6V1B2 CFD TLE4 YBX3 STK17B MAP1LC3B CEBPA DENND3 MAFG KLF7 LY96 COTL1 HPSE EVI2A B9D2 PPP2R5A SLC6A6 NRBF2 ANXA3 NCOA1 SRF PRCP PGD RNF141 SEC14L1 CYB5R1 HK3 RHOG IFNGR1 PALM PSTPIP2 RPS6KA1 TNFSF13 NOP10 BAZ2B APLP2 NQO2 ZNF267 CCNH BMP2K ICAM1 XKR8 DHRS12 CUL3 PTEN DAZAP2 IRF2 ZNF106 CLEC4E FTL SH3GLB1 ZYX HAS2	down	***
GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP	0.0000177	0.0002243	0.5756103	-0.3432408	-1.795559	158	CXCL3 KMO ASGR1 TRHDE RBMS2 DCSTAMP CLDND1 SIK1 RUNDC3B RCOR1 CAV1 BAIAP2 OTUD4 ATP2B1 SH2B3 FOXA2 ABCG2 BZW1 CSGALNACT2 GLS NDEL1 CRTAM BTG3 MCL1 PDGFA KRT4 MAP2K3 KLF4 SOCS2 PER2 ARC MATK SLC25A32 ADAMTS8 ZNF706 NINJ1 VPS37A UBQLN3 ADAMTSL2 NXF1 SERPINB8 AK1 PELI1 EHD2 BTBD7 MRPL39 TSC22D1 NAB1 GATA6 ACTN2	down	***
GSE3982_MAC_VS_TH2_DN	0.0000060	0.0000880	0.6105269	0.4000094	1.795177	172	RUVBL1 C17orf75 GPR35 ANKZF1 SAP30L-AS1 UMPS PRC1 ORC1 GINS4 NCAPD2 COQ3 HMMR DLG1 NLE1 KIF23 DPY19L2P2 STAP2 KIF15 NUP155 TFR2 MRPL3 MCM3 CDC25C CC2D1A DCTPP1 MEOX1 ERCC2 CKS1B DDX51 ASF1B DIDO1 BIRC5 GOLGA8A ALDOB ZNF692 DHX34 DAP3 GALNT3 NRF1 RMND5B RDH16 TSTA3 DGKA CDR2 KIF21B MED24 TDP1 EXOSC5 POLR2I ATAD2 KRTAP5-9 DPH5 PMS2P1 CCNA2 SNRPD2 CAPN10 PPP6R2 RHOT2 HOXB2 PNKP SRCAP DDX52 SYNE2 CLASP1 CFI ZDHHC13 NSUN5 BAG2 FAF2	up	***
GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP	0.0000023	0.0000384	0.6272567	-0.3363104	-1.793467	182	SIDT2 FCN1 CD101 ASGR1 PECAM1 MNDA LTA4H CAT LY86 LMO2 SAMHD1 MYD88 P2RY13 AGTPBP1 FUCA1 FRAT1 CD36 DPEP2 CD33 ENTPD1 CD37 CST3 RHOB CFD KIAA0513 CPVL KLF11 PLBD1 SELL CD302 HK3 FOS KLF2 ICAM2 CD74 BIN2 CHPT1 CD1D CBFA2T3 RPL21 DOK2 RGS2 MBNL1 HELZ RBL2 CCDC69 CEBPD ALDH2 SCPEP1 S100A4 METTL7A ICAM3 GIMAP4 DUT PIEZO1 SLC35A1	down	***
GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN	0.0000029	0.0000465	0.6272567	0.3996997	1.792984	173	FOXM1 CEP72 SPATA24 CDC45 TICRR GMDS BUB1B NEK2 CCDC34 CENPF TG UBE2T MND1 TTK GINS1 IQGAP3 IFT122 TRAIP ESPL1 MYBL2 MIS18A CISD1 SAE1 MRPL27 WDR66 TOPBP1 PIH1D1 HES6 BRIP1 RAD18 FADS2 CNPY2 PPIL1 EFCAB11 CDKN2C SLC25A13 SSX2IP DYNLL2 SAPCD2 MTBP RECQL4 PA2G4 SPEF1 DPP3 TUBG1 DHX40 MBD4 SUDS3 CHTF18 GINS2 PKP4 KIF20B LRWD1	up	***
GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN	0.0000065	0.0000940	0.6105269	0.3986255	1.791625	178	KIF20A PARPBP GINS1 SNF8 ESPL1 ACOT8 TPX2 CCNB2 GOLGB1 RBBP8 PRC1 MYL6B DCTN2 NME1 MELK EXO1 CISD1 RPL39L KIF15 KNTC1 BUB1 CCT5 AURKA KIF2C MCM7 COASY RRM2 PLTP TARS2 KDELR2 BLM TST ALDOA PARP1 CKS1B NUSAP1 TMEM106C CBX5 BIRC5 C1orf112 POLR3K NEIL3 FEN1 EZH2 MRPS12 IGSF3 LAPTM4B SNRNP25 DPP3 FAH PSMA5 MLEC FHL2 CDC7 DHTKD1 LIMA1 CDC20 ORMDL2 MCM6 PPCDC TDP1 LSM4 ATAD2 NUP62 RFC5 WDR77 RAD51 UQCRQ CENPE MTHFD1 PAICS PPIA BCAT2 RAD1 DDB2 DNM1L ILVBL IFI16 AKR7A2	up	***
GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP	0.0000065	0.0000941	0.6105269	0.3991749	1.791432	172	GMDS CHEK2 CENPF FBXO27 MPP6 THOC3 CDK4 GTSE1 SNF8 STIL EIF2B5 PLK1 NUF2 PTTG1 GPI ESPL1 TPX2 UHRF1 WDR90 MKI67 TOP2A EME1 SAE1 RAB19 DPCD RRM2 RAD54L KIF11 PASK CHAF1B ZNHIT1 CHEK1 ABCB9 PRMT6 BLM PPP5C ALDOA PTPN3 CDKN2C ASF1B EXOSC2 RFWD3 CENPH NCAPG ETFB DGCR6 DNMT1 MZT2B CCNE1 DPP3 KIF22 MRPL11 CHTF18 LRWD1	up	***
GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_UP	0.0001446	0.0013495	0.5188481	0.4420468	1.790682	82	HMGA2 UNC5CL TG CHRNG FOXE1 TSPYL5 STK31 CHRNA7 SIX1 RUNDC3A TRIM29 SLC16A8 CSRNP3 RSPO4 C7orf50 GAS8 LINGO1 SPAG6 SDCBP2 KY MMP7 TAC4 ANKRD1 EDAR TMEM17 YBX2 PAK4 NPTX1 FAM78B DPP10 ASCL2 TMEM169 CHMP6 ACSBG1 CRYGS LRIT3 HMG20B C1orf194 WIPF3	up	**
GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP	0.0000078	0.0001119	0.5933255	-0.3409265	-1.790458	164	CXCL16 IL1B MIR22HG SIK1 EGR2 BACH1 TMEM138 GPCPD1 S1PR1 YPEL5 FRAT1 ANXA1 BTG2 EIF5 SRGN SORBS3 DGKE LEPROTL1 KLF11 TADA2B CYP20A1 ID2 SNORA28 RNF139 SH3BP5-AS1 SLC25A32 MYH11 PIK3R5 IKZF5 VCPKMT SLC25A33 CCNY AREG DNLZ IFNGR1 PTGER4 ATXN1L CD83 RC3H1 TPP2 TSPYL1 ADNP2 KLF2 SRSF6 FAM204A CDC37L1 IRS2 TBRG1 KANSL2 SF1 IQSEC1 TXNDC11 PSME4 EDN1 ZNF791 DNAJB9 CYTH1 DAZAP2 C1orf52 SFPQ ZNF326 TNFSF8 ZFP36 TRPM7 SPTY2D1 NOL9 ZNF14 DDX21	down	***
GSE11386_NAIVE_VS_MEMORY_BCELL_UP	0.0000252	0.0003041	0.5756103	0.3990915	1.789925	168	TRIP13 MDM1 CDC45 BUB1B CCDC34 CENPF UBE2T PBK PGM2L1 NDC80 CDCA2 ASPM CDCA8 FIGNL1 PRC1 DTL MCM8 LILRB4 GINS4 SPDL1 MELK NDUFB8 KIF23 CEP55 KIF15 KNTC1 BUB1 AUNIP TOP2A MCM7 DPCD RRM2 RAD54L CDC25C RAD51AP1 PIH1D1 CDK1 GBP3 POLR3K NCAPG RAB11FIP4 CENPP EFTUD2 EDEM3 GALK2 GSS TUBB2A KIF22 HID1 KIF20B PSMD2	up	***
GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN	0.0000075	0.0001081	0.6105269	0.3972813	1.788471	183	TRIP13 PSPH PRIM2 BRCA1 ANLN NDUFS6 IFT27 ACAD9 ALDH18A1 MCM2 CCT6A XPOT TAMM41 NUDT1 CISD1 KIF23 MKI67 TOP2A POLD2 LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD CNPY2 CKS1B NUSAP1 MRPL37 CDK1 BIRC5 CCT3 GMNN POLR3K MRPL17 TSPAN31 EZH2 CBX1 NOP2 TPD52L2 TUBG1 TACC3 MNS1 TRIM37 DUSP12 NUP85 RAD50 CENPK CKAP5 CDC20 RPRD1B RRP9 RPL7L1 CKAP2 MCM5 HAX1 RCC1 PDIA4 HAUS4 RFC5 NME4 PDAP1 WDR77 INO80E HK2 PGAM1 SPR RPN1 POLR1A DDX52 CHERP DTD2 DDX41 CYB5B RCN2 MRTO4 LUC7L3 SRM PLK4 HRAS MRPL2 COQ5 GCSH ABCD3 PPA1 TIMM9 CRCP MTHFD2 POLD3 CTPS1 ACOT7 NUDT19 HMBS	up	***
GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN	0.0000100	0.0001375	0.5933255	-0.3403136	-1.786699	167	CD52 PNPLA6 STAC PECAM1 OSBPL1A HHEX MNDA CLEC3B ATXN3 LTA4H RUNDC3B LYL1 LY86 NXPH3 FCER1A CIR1 FUCA1 TGFBR2 GGA2 TXNIP UBL3 ABCG1 APOC1 FBXL5 TNFSF12 ZCCHC24 CPVL ACTR3 PINK1 HTT ADD1 PRCP FRY LRRTM2 LAMB2 KCTD12 DNASE2 BAG5 CAP1 NDUFV2 PLCG2 FOS RIN2 CTNNAL1 ATXN1 DOK2 NPTN PLA2G15 GPX3 FKBP1A VASH1 WDR1 ESYT1 HSPA8 S100A4 METTL7A CD1E P2RX1 NRG1 RNH1 EVI5 INTS10	down	***
GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_DN	0.0000301	0.0003511	0.5756103	0.3984239	1.784766	169	TICRR CHEK2 TIMELESS KIF18B BRCA1 TMC1 ASPM EBF3 TPX2 CCNB2 PRKCA CCNF RCCD1 NLE1 CHAF1A MKI67 KNTC1 POLD2 IGLV1-44 CDCA5 NT5C1B RPS2P45 SLC25A39 TIMM50 SPC24 DSCC1 BLM PSRC1 MRPL37 SERTAD4 C1orf112 E2F1 UNG SSX2IP EZH2 SPAG5 EFTUD2 C3orf67 POLR2H SNRNP25 MYO19 DNMT1 TUBG1 PUS1 RAD9A TJAP1 KIF20B ANAPC1 NUP85 PFAS CDC20 POP7 MGME1 MCM5 ACOT11 DDX23 SNAP47 SRSF1 SLC1A5 TCHP UNC119B GLO1 PRR11 CISD3 TXNL4B TARBP1 WDR76 TARBP2 CGN ALG1 PRPF3 SART3 KIAA0586 ZNF511 MRTO4 RNF126 ZC3HC1 TOMM40 SNHG17 TLE2 DUS3L GLRX5 URB2 TRIM59 RMI1 TBC1D2B CTPS1 TLE1 SKA2 MMP12 SLC39A3 SLC29A1 NRP1 TXNRD3 NVL GSR	up	***
GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN	0.0000095	0.0001312	0.5933255	0.3961278	1.783606	180	AK4 BDH1 BUB1B CCNB1 CENPF TTF2 SORD PHGDH NIPSNAP1 PLK1 CDC6 TPX2 CCNB2 TYMS MYBL2 CCT6A SHMT2 MYL6B NME1 RUVBL2 NDUFB8 HMMR CHAF1A PCCB CCT5 AURKA WDHD1 KIF11 MCM3 CDC25C CHEK1 AHCY IDH2 PARP1 TMEM106C HDGF NPM3 UNG PSMB5 FEN1 EZH2 SPAG5 FADD SRD5A1 CCNE1 TUBG1 GNPAT DLGAP5 SPTSSA CDC7 CKAP5 STAMBP MRPL28 HAX1 SLC1A5 NEFH FARSA AP2S1 PYCR1 PRIM1 GBP1 ATOX1 TMED9 ETHE1 VDAC3 CENPE MTHFD1 TP53 PAICS UBE2C BCAT2 ENO1 CYB5B SRM TOMM40 NHP2 PMVK CRYZ CCDC6 HNRNPAB MTHFD2 COX6A1 GRHPR EBNA1BP2 LAG3 CTPS1 PSMD8 ACOT7 ACTN4 COL6A3 SLC29A1 RFC3	up	***
GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0000104	0.0001426	0.5933255	-0.3366117	-1.783206	175	NLRC4 CXCL16 COQ2 CD44 MYD88 ELF2 STX11 FGR IER2 SH2B3 TACC1 RASGRP4 ANPEP SERPINB9 C1orf162 PPP3CA CD93 SPI1 MCL1 CST3 TLE4 ZSWIM6 RRM2B LINC00324 NFKB1 P2RY2 SELL HPSE KCTD20 ARAP3 TM6SF1 CD53 DUSP1 DSE CNOT6L FLT1 CTSS OASL UTRN DNAJA1 IPO7 FRYL RAB8A PLCG2 ADNP2 NOP10 USP7 TREX1 VAV3 SERPINB1 NAB1 IFNAR1	down	***
GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_UP	0.0000215	0.0002663	0.5756103	-0.3399596	-1.782254	163	GPD1 ANGPT4 LPIN2 SASH1 SLC12A6 PECAM1 LMO2 CYB5R3 PLEKHA1 RCHY1 ABCB1 DNASE1L3 CLCF1 SIRPA UBE2D3 KRT4 EFCAB14 MEFV ST3GAL2 OSTF1 MYO1B EPM2A ITGAX UBE2E2 PTPRC ARHGAP9 B9D2 MATK RNF149 OXNAD1 HPGDS SLC14A1 HRH1 MED30 TREM1 RAB8A STX5 TUBGCP3 NDST1 YTHDF3 KANSL2 IST1 CCR6 TNFAIP8 RTN1 PIP4K2A ILKAP FNBP4 THEMIS2 USP48 FCRL1	down	***
GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_DN	0.0000032	0.0000498	0.6272567	-0.3385214	-1.781910	170	PECAM1 GLIPR2 PTPRE LMO2 MEF2A TXNIP KLHL30 ANXA1 CD5 SERINC1 IL18R1 TNS1 TAPT1 ITM2B RIT1 PLEKHB2 FCER1G ALOX5AP KLRD1 CD300LB MOB3A AFF3 SNN NRROS EMP3 SNX3 HPGDS NOTCH1 MN1 ATP6V0B TYROBP IFNGR1 RPS6KA1 TMEM167B DOCK8 FAM177A1 UVRAG CST7 WDR7 GPRIN3 ECI2 NKG7 CRYZL1 CBFA2T3 NAB1 ATP6V0C NQO2 GABARAPL1 DECR1 BMP2K SLC43A2 LDLRAD4 CALHM2 SRP72 HNRNPC ABI3 KIT DOCK10 PTEN EVI5 ARFGAP3 SLC35A1 CYBA TNFSF8 ITGAL MAMDC2 NCF1 TBC1D23 C6orf62 FXYD5	down	***
GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN	0.0000129	0.0001695	0.5933255	-0.3395839	-1.779400	165	PECAM1 HHEX PTPRE LIPA FYN MMRN1 LMO2 ST3GAL6 TBXA2R NR3C1 SCARF1 ERG EDEM1 UBL3 ADA ITGA5 KLF10 GLS HLX ZFYVE16 PPP3CC ZMIZ1 KDSR EFCAB14 STX3 SOCS2 KLF7 CDS2 RECK ALOX5AP GNAQ AFF1 ARL6IP5 MAP4K4 AK1 GYPC PTGER2 SERPINB6 PPM1F ACSL1 FOXO3 BAZ2B PDE4B ETS2 SYT11 ARAP2 SLC31A1 SEC63 CALCOCO2 TMEM87A GPR171 THEMIS2 CREG1 BMI1 LYZ DMXL2	down	***
GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN	0.0000105	0.0001435	0.5933255	0.3951871	1.779371	180	TRIP13 CDC45 MCM10 NUP107 GGCT CDK4 ALDH18A1 ESPL1 CDC6 MCM4 MCM2 CDC25A PRC1 CCT6A SHMT2 XPOT CDT1 CCT2 NME1 RANBP1 HMMR EXO1 EEF1E1 AUNIP WDR3 POLD2 MCM7 MRPL3 PKM CHEK1 DNAJC9 DCTPP1 BLM CKS1B EXOSC2 UCK2 GMNN SMG9 PSMB5 MRPL17 FEN1 PA2G4 POLR2H TUBG1 SCLY LMNB2 TUBA3D MLEC GINS2 ASNS CCT7 CDC20 STOML2 BCL2L1 NOL6 MCM6 GINS3 SLC1A5 SHCBP1 ABCF2 MTHFD1 TP53 PAICS CISH ENO1 TUBA1C SMARCB1 RRS1 NUP93 KLHL2	up	***
GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN	0.0000125	0.0001652	0.5933255	-0.3398038	-1.778965	162	CXCL3 EREG IL1A OLR1 IL1B EMP2 PTPRE CLDND1 NEDD4L CYB5R3 FXYD2 NCF2 IL1RN NUMB SLC44A2 ENTPD1 CSGALNACT2 RGCC SLC25A37 EVI2B MAP2K3 PAQR5 VASP PTPRC CXCL2 SELL CD53 FCER1G PIK3C2A EVI2A AFF1 CLN8 EMP3 RAC2 TREM1 PLK3 FAM43A CXCL5 FOS KLF2 PKD2 TSHZ3 PIK3AP1 FXYD6 NUP153 PDS5B TSPAN14 GPR84 ADPGK ETS2 CCL20 MIR155HG MS4A4A TAB2	down	***
GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN	0.0000108	0.0001477	0.5933255	0.3949431	1.778272	180	CDC45 MCM10 UBE2T TTK CDK4 ASPM EIF2B5 ECT2 CDC6 SFXN1 PRC1 CCNF EIF3B DTL RUVBL2 POLD2 MCM7 RRM2 PKM MRPL27 KIF11 ZNHIT1 TOPBP1 MAD2L1 AHCY ALDOA UQCR11 SSBP1 PSAT1 EZH2 DYNLL2 MRPS12 UQCC2 DDT EIF6 UBFD1 DPP3 GNPAT COA3 UBAC1 PSMA5 LONP1 KIF22 MRPL11 DTYMK POLD1 MARCKSL1 TIMM13 CPSF4 STOML2 LRRC59 MRPS33 MRPL51 NUP62 FARSA BANF1 MRPS25 PDAP1 PRPF31 SEC13 OXCT1 NDUFA8 ACP1 SMC2 GPN1 NDUFB7 NUP93 COX17 NCAPH DRG1 MRPL12 EIF2B1 CLPP TNPO3 EXOSC10 TMPO CDC34 TRIM59 ARL1 MTHFD2 PFKL COPS7A STMN1 ITPA EXOSC7 MRPL35 MRPL13	up	***
GSE7852_LN_VS_THYMUS_TCONV_DN	0.0000080	0.0001132	0.5933255	0.3951656	1.778199	179	PARPBP MCM10 CCDC34 IGF2BP3 TIMELESS PBK DEPDC1 TTK E2F8 PLK1 CENPA ECT2 ESPL1 CDC6 NNT FIGNL1 UHRF1 STRIP2 PRC1 CCNF MELK TOP2A SFI1 KIF2C MCM7 E2F2 CDCA5 RAD54L SOX4 PFKP RAD51AP1 DSCC1 PTGFRN BLM SKP2 CKS1B NCAPG2 NUSAP1 ASF1B CDK1 ABHD17C AAGAB EZH2 RALGPS1 CBX1 CENPP ALDH7A1 TRIM37 ITFG2 GK5 ATAD5 ATP13A1 SASS6 SUPT16H CDC20 RPL7L1 CENPT RAB3D SUOX MARCKS ZNF212 PRIM1 PRR11 DBNL CAP2 RAD51 PTPRF CENPE FRMD6 UBE2C C4orf46 NCAPH TTC5 RNF14 CEP290	up	***
GSE3982_BASOPHIL_VS_TH2_UP	0.0000179	0.0002263	0.5756103	-0.3376390	-1.777031	169	EPAS1 ABHD5 OSBPL11 PECAM1 PTPRE FIG4 LYL1 PLEKHF2 ST3GAL6 AGTPBP1 EPB41L3 PILRA ANXA1 CD33 EIF1 NLK PTX3 SIRPA CLK1 ZFYVE16 BST1 DRAM1 TMED5 SOCS5 NPR3 CCSER2 PIK3C2A N4BP2L1 DSE PPP2R5A PAFAH1B1 TDRD7 TMOD1 PDCD6IP NECAP1 ARHGEF10 JAK1 PSTPIP2 RASSF2 RHOQ CALM1 MBP CHPT1 GSAP BAZ2B GALC MACF1 N4BP2L2 SERINC3 ARAP2 LRP12 CYB5R4 ACTB MEGF9 OSER1 KIT TMEM87A CREG1 DCUN1D2 UBAP1 SVIL OSGIN2 ZBTB7C PTGS1	down	***
GSE23925_DARK_ZONE_VS_NAIVE_BCELL_DN	0.0000123	0.0001635	0.5933255	-0.3381426	-1.775301	167	EGR2 VAMP2 BCL2A1 TRIB1 IER2 CCNL1 SH2D6 PPP1R15B CSRP1 GATA3 NR4A1 JAM3 SRGN MAPK8IP1 BTG3 EIF1B CSRNP1 ITPRIP PTPN21 CASKIN2 ID3 STK17B CCL4 PNRC1 PER1 DUSP1 ELMSAN1 SH2D2A MAFF MOB3A SRF ETF1 SENP3 ETV3 ARL5B PLK3 JUNB KLHL18 EGLN2 SLC3A2 FOS FOSB DUSP5 AOX1 ATP6V0C MFNG TMA7 KTI12 UNC13D GEM SELPLG TOB2 ISCU GPR171 CCND3 HPCAL4 MED31 PIM3 EGR1 DUSP6 NR4A2 EYA3 ZFP36 YRDC CD69 DNAJB1 BCL10 TRMT10C NCOA7 NFKBIZ KBTBD2 DUSP2 ZCCHC14 FBXO33	down	***
GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_UP	0.0000155	0.0001987	0.5756103	0.3987710	1.774552	161	CA9 FAM153A CLGN DEPDC1 BRCA1 LCN2 COLQ TRAIP POLE CEP70 GPI TFDP2 ARHGAP33 SMARCC1 BUB1 TOP2A AURKA POLD2 PRKDC RAD54L MRPL3 MCM3 C11orf16 POLR3C DNAJC9 CC2D1A BRIP1 FNTB REPIN1 IDH2 MGLL HSPBP1 SKP2 TNFRSF21 ATP2A1 TRIM2 EZH2 STK11 MYO19 TUBG1 ALDH7A1 NINL MLF2 SNRPA TK1 KRI1 ZSWIM1 ZNF282 POLD1 ATAD5 PFAS CXCL1 THOC5 METTL2B LRRC17 NOC4L CLUH U2AF2 MICAL3 GLO1 ABCF2 CARHSP1 ZWILCH FAIM BCAT2 WIZ NCAPH ACSBG1 PRSS50 BAG2 PLK4 TBC1D10B HINT1 VAC14 GLRX5 DCLRE1B MSH6	up	***
GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN	0.0000122	0.0001634	0.5933255	-0.3384698	-1.774477	171	RTKN2 IL17RB PDLIM2 SGK3 GLIPR2 ANXA1 KIAA0355 DNAJC3 HBEGF PCYOX1 CLN5 PLXNA4 HNRNPDL TXN LINC00528 CASP1 SOCS2 MAFG TMBIM1 SELP UXS1 PLEKHB2 TDRD7 DDX60L CHDH ATP6V0B LYRM1 IDS PTGER2 TIGIT CLUHP3 KLF2 ICAM2 ABHD13 SBF2 IRS2 RIMKLB N4BP2L2 ZNF267 MEGF6 KAT2B HAUS3 CCR6 PDLIM5 CDC42EP3 CXCR4 TAB2 G3BP2 DNAJB9 CYTH1 NR3C2 LPAR6 IL16 TNFRSF10D ACVR1C CDC14A ITGB1 FTL SLC26A11 HLA-DRB1 CCDC93 ARHGEF12 RCBTB2	down	***
GSE12366_GC_VS_MEMORY_BCELL_UP	0.0000352	0.0003988	0.5573322	0.3959819	1.773827	169	HELLS KIF20A GALNT14 MCM10 CENPF TIMELESS APOLD1 PBK DEPDC1B GINS1 CDCA2 TPX2 E2F3 UHRF1 MCM4 SPATS2 SLC35E3 MCM2 ARHGAP33 XPNPEP1 DTL ZNF608 SCG5 C5orf34 FBXO43 SAE1 MCM7 WDR78 CDCA5 RAD54L MCM3 WDR66 LMNB1 YEATS2 RNFT2 CHEK1 SPC24 PARP1 PSRC1 C12orf75 TMEM106C ENPP3 PEG10 SPAG5 ZNF827 NET1 DNMT1 ST14 TUBB2A TK1 CDC7 DNASE1 CDC20 CENPM ASRGL1 ROMO1 DPY19L2 LRIG1 ATAD2 CEP152 ESRRB SYBU RAD51 ZWILCH	up	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP	0.0000092	0.0001280	0.5933255	-0.3339011	-1.773611	177	LPIN2 SASH1 SWAP70 TSPAN4 HHEX RAMP2 CD44 LMO2 ESAM CLEC10A S1PR1 CD9 TGFBR2 ZEB2 ANXA1 NFIX CD33 IL18R1 CD93 MAP2K3 KLF4 STX3 SOCS5 TMBIM1 MARVELD1 UBE2E2 VIM C9orf72 SMAD7 VAMP5 PRDM5 PROCR PRCP MYO1C VAMP3 RNF149 ASNSD1 PSMA1 GLUD1 TYROBP PTGER2 CST7 RHOQ SERPINB1 CRYZL1 TSC22D1 ORC2 CD81 DOK2 MEIS1 PLA2G15 YAF2 ARRB2 KIT NFU1 THEMIS2 GRB10 MT2A EHD4 RNH1 FCRL1 NIPSNAP3A	down	***
GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN	0.0000632	0.0006632	0.5384341	0.4062277	1.773341	134	CECR7 IGF2BP3 PDCD2L SLC5A1 STK31 ENAM PTTG1 PLEKHA7 APOL2 KCNJ8 LIG3 AK8 GPX2 SIPA1L3 HAUS5 C6orf132 PPP1R9A C1orf220 FANCA APOL1 HORMAD1 SP140L ARHGEF34P PES1 MIPOL1 DCLK1 C2orf50 CDK12 IGHG1 ACSBG2 RANGAP1 ARFRP1 HNRNPA1L2 RHOC PSME2 OSBPL3 C19orf12 RGS22 SLC9C2 S100A13 HLA-A ZNF202 CDR2 TRIM56 ACTRT3 KPTN MYH3 TMEM253 ZNF257 GBP1 OXCT1 GBP2 VPS9D1 DNPEP ENPP5 CASC2 TRIB2 PIGL CLDN10 ENO1 E2F7 WIZ NLRC5	up	***
GSE24142_DN2_VS_DN3_THYMOCYTE_UP	0.0000041	0.0000629	0.6105269	-0.3366943	-1.772293	170	CD52 IL17RB TSPAN4 TAL1 HHEX PTPRE LYL1 SH2D3C CD44 MYADM AQP9 CLEC10A CD9 ANXA1 LACTB HBEGF GM2A LITAF SRGN SPI1 RHOB SLC7A8 ITGAX VIM CD302 PTGER3 ALOX5AP MAPRE2 PROCR CABLES1 RGS18 TAS1R1 CD48 RAB31 TYROBP GLIPR1 SELENBP1 PI4K2B HSD17B12 OGFRL1 TAGLN2 CST7 CD34 CD151 SLC25A24 CPA3 IRF5 VAV3 SERPINB1 CRYZL1 CTNNAL1 PIM1	down	***
GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_UP	0.0000165	0.0002107	0.5756103	0.3969359	1.772076	164	KIF20A CDC45 ELOVL6 NPAS1 PSPH NDC80 RACGAP1 E2F8 ANLN TENM2 CDCA8 AURKB CENPA CDC6 CCNB2 UHRF1 PRC1 CCT6A CDT1 RANBP1 EXO1 NUDT1 KIF23 TOP2A POLA2 RRM2 MRPL27 CDC25C SOX4 RBP1 EGFR CHEK1 DNAJC9 ORC6 MAD2L1 AHCY GAS8 XRCC1 TULP3 CKS1B DRC1 NUSAP1 CDK1 POLE2 BIRC5 SRCIN1 EZH2 DIAPH3 COL1A2 KIF22 TK1 CENPK SLC26A1 CDC20 CKAP2 SURF2 LSM7 NFE2 RPS26 CCNA2 PRIM1	up	***
GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN	0.0000381	0.0004279	0.5573322	0.3990897	1.771322	158	SLCO5A1 SPICE1 EYA1 SPOCK1 CDC45 TROAP UCHL1 KIF18B PLK1 IGKV4-1 LAMP5 TPX2 CDC25A SPINK1 CDT1 TNC EXO1 SOX30 RAD54L OAZ3 SARS2 KDELR2 IGKV1-5 ASS1 SCAMP5 GAS8 EHHADH BLM TSHR ASF1B CDK1 EFCAB6 BIRC5 SPAG5 QPRT NRGN EFCAB2 KIF22 TK1 NOC2L COG4 ZNF814 MAT1A CHPF ASRGL1 SSH3 RABEPK LANCL2 HAX1 YIPF2 SUOX MYH3 NT5DC2 PYCR1 CEP85 HOXB2 CTTN TIMM44 UBE2C COPZ2 DHRS9 ZBP1 CALU	up	***
GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN	0.0000060	0.0000880	0.6105269	-0.3325621	-1.768135	180	EPAS1 NLRC4 EREG CD300LF CD52 ABHD5 DENND5A DCSTAMP LPXN ENG PRAM1 ARIH2OS FLVCR2 GPCPD1 TBC1D2 LAMP1 FGR GGA2 CASP9 DNAJC5B ADAM17 ABCG2 FAM89A ABHD6 APOC1 LCMT2 BST1 PLBD1 CTSD ATF3 TLR4 MFSD11 WFS1 IL7R FKBP15 HEXB CABLES1 NXPE3 PRKCE SIGLEC15 SERPINB6 ACSL1 GPRIN3 HIVEP2 CR1 PNPLA3 MME TGFB1 CD1D TSC22D1 TMEM230 APLP2 GABARAPL1 FCGRT DECR1	down	***
GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN	0.0000088	0.0001226	0.5933255	-0.3303172	-1.766653	183	HHEX SOWAHC ZC3H12C LYL1 LY86 LMO2 TMOD3 MYADM INPP5A NCF2 FUCA1 CD22 GGA2 ANXA1 PLA2G7 SH2B3 SLC7A7 GM2A MAP3K8 IFI30 PBX3 MS4A1 PPP3CA ADRB2 CD93 CD37 PPP3CC CDIP1 PLBD1 CLIC4 PER2 PDE1C HLA-DQA1 HCK MTPN TCTE3 PKIG LIMD1 KCTD12 CTSZ ATP6V0B SNX2 CD83 IRF8 PRKCE PXK PLCG2 SNX9 RHOQ IRF5 TCF4 SERPINB1 TEC CBFA2T3 CD81 BMP2K CCR6 SLC31A1 SPIB CXCR4 ALDH2 CD19 CTSC MCOLN2 IQGAP1 EVI5	down	***
GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_DN	0.0000172	0.0002193	0.5756103	0.3968971	1.766213	161	SLC2A1 TBRG4 PHGDH NIPSNAP1 TRIB3 PLS1 IKBKE NR2C2AP CHAF1A PAFAH1B3 MSX2 LARS2 PDCD5 AKAP1 TRPT1 AIMP2 SALL2 EEFSEC FNTB STXBP4 CXCL11 ISOC2 DDX51 PGBD2 PSAT1 GAL3ST4 PARS2 PDCD11 ZNF671 RAD51D DPH2 ZNF239 TRIM32 KRBA2 PEX10 TCEA2 ZFP69B PFAS TIMM13 L3MBTL2 SIRT4 RRP9 FAM50B ZSWIM8 SURF2 RAB15 ZBTB9 RCC1 LHPP FARSA ZNF224 AGMAT DTHD1 ABCF2 WDR77 ZNF71 EARS2 ROBO1 TMEM256 TMEM161A ALKBH2 PHRF1 CYHR1 ZNF511 SCRN2 PDK2 TMEM229B ZNF514 ZKSCAN4 LZTS2 MSH6 FCGBP NCOA5 ELP6 LFNG COQ4 IPO4 ZNF235	up	***
GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP	0.0000079	0.0001124	0.5933255	-0.3348825	-1.765721	173	CXCL3 EREG IL1A CD55 IL1B CLDND1 PID1 COQ2 BCL2A1 SLC11A1 STARD4 ATP2B1 PTPRM CARD16 ADAM17 EIF1 SWT1 RAB33B MPHOSPH6 TCF7L2 TMEM38B AGO3 CASP1 PLAUR SOCS2 CXCL2 ALOX5AP PINK1 OXSR1 IL24 KREMEN1 STK24 PKIG FMNL2 FLT1 DDX60L RNF149 SH3BP5 CELF1 CARD8 PNPLA8 ZBED5 CDK14 SNX9 HIVEP2 TGIF1 FAM228B TEX30 DUSP5 RIMKLB INO80D CCL20 BNIP3L CDC42EP3 GIMAP5 BCAT1 RAB2B	down	***
GSE7852_THYMUS_VS_FAT_TCONV_DN	0.0000064	0.0000932	0.6105269	-0.3321996	-1.763201	178	LPXN PTPRB SIK1 RUNDC3B CAV1 MYADM BCL2A1 AGPAT4 B3GNT5 LATS2 ZDHHC2 LUZP1 LITAF IL18R1 CD93 BTG3 IL10 CFD AGO3 DGKE STX3 TMBIM1 NR1D2 SIK2 ATF3 HOPX PLEK ARL4A CPT1A SPRYD7 BCLAF1 MAFF CRIM1 MAPRE2 FLT1 TAS1R1 SNHG8 PPP1R15A PTGER4 REL DENND4A TAGLN2 CST7 RRAS HIVEP2 MBP RUNX3 FOSB AKIRIN2 TEC TSC22D1 RELL1 RGS2 BMP2K ITPRIPL2 CDC42EP3 CXCR4 TAB2 DAPK1 DNAJB9 SAMSN1 LDLR NAF1 SLC38A2 EFNB2 TSC22D2 ATP2B4 NFIL3 ATF6 IMPACT MRPL16 AKAP13 NFKBIZ GZMB MYO1F ZCCHC14 PNP PLXNC1 KLRG1	down	***
GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP	0.0000233	0.0002834	0.5756103	-0.3346657	-1.761382	169	EPAS1 ACE SLC47A1 PECAM1 ZC3H12C FBP1 CLEC10A MSRA MKNK1 NCF2 ANAPC15 SPCS3 DNASE1L3 ASAP1 SGMS2 TACC1 LMNA ABCG2 BTG2 PARVG PTX3 C1orf162 CD93 TAPT1 MAP2K3 PPT1 PRKD3 ABCC4 TM6SF1 HTT PEAK1 UBASH3B ARHGDIB CYB5R1 SNX29 GLIPR1 GMFG ATP13A3 HOMER1 CLN3 SRSF6 TPMT STX12 PLEKHO2 MBNL1 RXRA ABL2 CDC42EP3 ESYT1 ALDH6A1 MEGF9 GPD1L S100A4 ICAM3 CBX7 ZNF106 ATP11B PLXDC2 ATP1B1 PTGS1 FXYD5 NXN ATP8A1 SKAP2 NCOA7 TTC39B NFKBIZ CYP1B1 GALM GSN PYCARD UQCRB	down	***
GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN	0.0000118	0.0001596	0.5933255	0.3912861	1.760741	179	TG PSPH SLC2A1 DDIT4 PRIM2 BRCA1 ANLN NDUFS6 ACAD9 ALDH18A1 TRIB3 MCM2 XPNPEP1 XDH XPOT TAMM41 CISD1 KIF23 MKI67 PAFAH1B3 BUB1 TOP2A LMNB1 FAM162A LIG1 CHEK1 MAD2L1 RAD51AP1 CNPY2 CKS1B NUSAP1 CDK1 BIRC5 GMNN POLR3K MRPL17 PSAT1 TSPAN31 EZH2 SPAG5 TPD52L2 SNRNP25 DNMT1 ELMOD3 TUBG1 TACC3 SLC37A4 TRIM37 HIP1R SAP30 RAD50 CENPK CKAP5 CDC20 CKAP2 MCM5 HAX1 RCC1 PDIA4 HAUS4 STK39 UNC119B KLHL7 NDUFV1 RFC5 HK2 PGAM1 RPN1 DDX52 DTD2 LXN NCAPH CYB5B RNF14 UNC119 RCN2 MRTO4 PLK4 HRAS TRAFD1 CYTH3 APBA3 PTGR1 CCDC6 MLLT3 CMPK2 TIMM9 CRCP MTHFD2	up	***
GSE45365_NK_CELL_VS_CD11B_DC_DN	0.0000101	0.0001390	0.5933255	-0.3286499	-1.757735	183	SIRPB1 CD300LF OLR1 IL1B CD44 FOSL1 SLC15A3 STX11 IL1RN PILRA EIF4A1 HBEGF PPP1R15B CLEC7A BTG2 PTX3 STOM SPI1 TUBB6 TIPARP PTPN12 CSRNP1 STAT5A MEFV MPEG1 VASP ADAMTS9 PLBD1 CLIC4 EPGN CXCL2 CCL4 DUSP1 MAFF CD300LB ARHGDIB NRROS RNF149 IL6 RAB31 TREM1 JUNB JAK1 OSM GPRC5A SLC3A2 FOS TGFB1 FPR2 DUSP5 CD86 PIM1 PDE4B ETS2 IST1 ICAM1 SELPLG ADAMTS4 IER5 RND1 NFKBIA ZFAND2A JDP2 EGR1 CSF2RB SERPINE1 CLEC4E S100A8 ZFP36	down	***
GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN	0.0000149	0.0001920	0.5933255	-0.3317875	-1.757650	175	IL17RB ASGR1 HVCN1 HMGCR BCL2A1 CD9 MOB1B HEG1 LACTB LMNA MAP3K8 CSGALNACT2 PAG1 LAIR1 C1orf162 PLXNA4 PDE4D KPNA5 ADARB1 ARRB1 ITPRIP SGTB SDCBP PLAUR DOCK9 RIT1 HOPX FXYD7 UBASH3B PTGIS COPS4 FOXN3 NRROS SERTAD2 ARHGAP17 SPIN1 RAB8B CD48 ETV3 GAS2L1 MPZL3 PSTPIP2 OSM MORC3 SIGLEC17P MBP MSMO1 ZNF575 GIMAP1 RELL1 TAGAP STK40 JUND IL18 TNFAIP8 CALCOCO2 HAVCR2 S100A4 SCAI SAMSN1 TLK1 MAN1C1	down	***
GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN	0.0000821	0.0008364	0.5384341	0.4023195	1.756281	134	CPNE4 FOXM1 KIF20A BUB1B CCNB1 CENPF PBK RGMB-AS1 GINS1 E2F8 KIF14 STK31 CEP70 NUF2 CCNB2 MCM2 TYMS GRHL3 GLDC DTL KHDC1 ZWINT CLPTM1L HMMR CEP55 SDHA MKI67 EMC9 KIF15 AURKA IGLV1-44 MSX1 RRM2 ANKRD16 SPC24 WWC1 CDK1 DMGDH NCAPG STEAP1 SPAG5	up	***
GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN	0.0000256	0.0003083	0.5756103	-0.3334912	-1.755201	169	CXCL3 EREG SPN CLDND1 EGR2 HCAR2 PRPF38A STX11 MARCO TSHZ1 TRIB1 HEG1 TMPRSS6 ITGA5 TNIP3 TMEM123 SLC7A2 PTPN12 TAPT1 BIRC2 TNFSF15 DRAM1 TMED5 RMDN3 ITGAX GPR85 GCA N4BP1 PIK3R5 HTRA4 KREMEN1 TDRD7 PROCR FMNL2 PPP2CA PHTF2 DDHD1 PNO1 APPL1 CPEB4 SHOC2 DUSP8 HSD17B12 ECI2 TAGAP GPR18 AMD1 IL18 VASH1 WDR1 XKR8 EPHA4 RIPK2 MEX3C POLR2M SDAD1 ZDHHC5 SAMSN1 MIER3 SPATA13 SLC16A10 ABI1 SERPINE1 ITGAL DCUN1D3 DYNC1I2 PIK3CG	down	***
GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_DN	0.0000143	0.0001861	0.5933255	0.3899265	1.754623	179	TRIP13 KIF20A HJURP BUB1B CENPF PBK DDIT4 PRIM2 STIL PLK1 AURKB TPX2 MCM2 XPNPEP1 NCAPD2 CLPTM1L MELK CISD1 MKI67 TOP2A SAE1 MCM7 MPO KIF11 MCM3 CHAF1B LIG1 MAD2L1 AHCY RAD51AP1 INCENP TMED3 CKS1B NUSAP1 CBX5 HDGF RFWD3 GMNN GOT2 DNA2 SDCBP2 TSPAN31 ETFB DIAPH3 CCNE1 DPP3 DLGAP5 FANCF SNRPA TRIM37 DTYMK MRPL4 ANP32E CENPV CDC20 POPDC2 PELO MCM6 SRSF1 LRRK1 STK39 APOBEC2 ZWILCH TBCB SMC2 RPN1 MTHFD1 ZBTB32 NDUFB7 COX17 ACSL5 ESM1 ACSBG1 SLC38A10 PLK4 FAM120A	up	***
GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP	0.0000074	0.0001063	0.6105269	-0.3299787	-1.754400	180	HHEX ZC3H12C SNX10 LYL1 HSD17B11 LMO2 TMOD3 MYADM GGA2 PTS UBL3 SLC7A7 SBDS ENTPD1 IFI30 PBX3 MS4A1 RB1 TMEM123 NDEL1 SPI1 MCL1 RAB14 TUBB6 TIPARP ARRB1 MPEG1 CASP1 KLF4 PLBD1 PDE8A SELL EPS15 HLA-DQA1 HCK MTPN PKIG ASNSD1 PHTF2 CTSS LIMD1 GABPA CTSZ SNX2 STX7 PRKCE RHOQ CD74 IRF5 TCF4 TEC WBP2 SERINC3 PPID IL18 SPIB VPS4B CD19 DNAJB9 MCOLN2 IQGAP1 RNF13 KLC1 CTSH ZNF106 DRAM2 LMO7 CD79B GPR137B FCRLA ITGA6 RNGTT WDFY2	down	***
GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP	0.0000058	0.0000858	0.6105269	-0.3294726	-1.753416	184	ZC3H12C LYL1 LY86 INPP5A DYRK1A BCL2A1 NCF2 WBP4 CYP4A11 CD22 GGA2 SH2B3 UBL3 LATS2 PPP1R15B MS4A1 SRGN UBE2D3 MCL1 RAB14 EPB41L2 MPEG1 PLBD1 FAM49B SELL PLEKHB2 SMNDC1 HLA-DQA1 HCK SACM1L MTPN PKIG ASNSD1 LIMD1 KCTD12 ETS1 RCAN1 SNX2 SKIL EEA1 CD83 RASSF2 PLCG2 SNX9 RHOQ CD74 IRF5 TCF4 AP1G1 SERPINB1 VAMP4 TEC GNA13 ADAM10 SERINC3 IST1 CCR6 ICAM1 SPIB ARIH1 CD19 CTSC DNAJB9 EID1 EVI5 DNAJA2 EIF4G2 CTSH CNR2	down	***
GSE3982_NKCELL_VS_TH2_DN	0.0000134	0.0001749	0.5933255	0.3901655	1.752336	175	KIF20A FANCI GGCT KIF18B TSFM STIL CENPA PTTG1 ESPL1 SFXN1 E2F3 CCNB2 RBBP8 TYMS CDC25A DTL CCT6A GINS4 NCAPD2 COQ3 LDHB MRPL15 AURKA POLA2 KIF2C RRM2 PDCD5 RAD54L MRPL3 KIF11 MDM2 INPP4B SYMPK NOL3 CKS1B NCAPG2 NUSAP1 TMEM106C SSBP1 POLE2 BIRC5 C1orf112 GMNN NCAPG PSMB5 SNRPE RTCB LONP1 GINS2 KIF20B DAP3 CCT7 CKAP2 UTP20 MCM5 HEATR1 TDP1 SRSF1 ATAD2 MSH2 CCNA2 HK2 RAD51 LRRC8B GRAMD1B RPUSD2 TNS3 SMC2	up	***
GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP	0.0000127	0.0001673	0.5933255	-0.3323246	-1.751743	172	WEE1 CD52 SWAP70 USP12 CD55 LY86 PLEKHF2 S1PR1 BCL2A1 CD22 TXNIP ATP2B1 ENTPD1 MS4A1 CD37 EPB41L2 RHOB SYNPO FOXO1 YBX3 DENND3 CLIC4 DOCK9 LBH SS18L2 MBD2 HES1 IL24 BTG1 PHTF2 PIKFYVE JUN JUNB SNX2 CD83 IGKV3-20 CDK14 PLCG2 RHOQ PELI1 KLF2 CR1 GSAP VPREB3 PDLIM1 IRS2 GPR18 SPOCK2 CCR6 MOB3B TNFAIP8 CDC42EP3 SP100 ICAM3 CD19 LYST CNN2 BANK1 AFTPH ARHGEF18 EGR1 CDKN1B NUP88 PLEKHA2 TUBA1A CD69 CD79B PAX5 MTSS1 GABPB1	down	***
GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN	0.0000187	0.0002350	0.5756103	-0.3340694	-1.751678	166	SC5D ZC3H12C LRRC8C RAPGEF2 STX11 MOB1B FAM49A IGSF6 PILRA TRA2B SBDS EIF1 SDE2 ITGA5 HDC MOB3C TMEM123 NDEL1 TMEM38B ATP10A CSRNP1 COQ10B ZFAND5 UBQLN1 KPNA3 PROCR CLIC5 GPBP1 ETF1 SAR1A PHTF2 SOCS3 OASL LIMD1 WTAP PCGF5 HSD17B12 AP3B1 ECI2 EHD1 JMJD6 TSC22D1 CSDE1 TAGAP PHF11 AMD1 XKR8 SETDB2 SEMA4A RIPK2	down	***
GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN	0.0000380	0.0004279	0.5573322	0.3928039	1.751547	163	TRIP13 GMDS TROAP CENPF POLQ NUDCD3 ANKZF1 ALDH18A1 FIGNL1 STC2 UHRF1 HPS3 RCCD1 MAGEF1 RUVBL2 HLTF FSD1 B3GNTL1 BRI3BP SLC9A3R1 THYN1 CBY1 PIH1D1 BRIP1 FNTB PHB DLG5 FGGY C12orf75 ASF1B UCK2 ATIC POLR3K ZNF775 MAD2L2 DIAPH3 ITPR3 ZNF692 PIAS3 MRPS34 MRPL11 MTA3 PINLYP FUCA2 DHTKD1 P4HA1 TIMM13 CENPM ACLY RABEPK SNAP47 GINS3 HAUS4 DPH5 SUV39H2 ABHD10 GBP2 CDK5 WDR76 ETHE1 PCBD1 NCAPD3 DDB2 CYHR1 AKR7A2 HEXIM2 MRPS16 PM20D2 FAM120A JAKMIP2 SRI PSMB10	up	***
GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN	0.0000129	0.0001695	0.5933255	0.3885959	1.749993	182	TRIP13 PSPH PRIM2 BRCA1 METTL1 ANLN NDUFS6 ACAD9 ALDH18A1 MCM2 XPNPEP1 CCT6A XPOT TAMM41 NUDT1 CISD1 KIF23 MKI67 TOP2A LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD CNPY2 CKS1B MRPL37 CDK1 BIRC5 CCT3 GMNN POLR3K MRPL17 TSPAN31 EZH2 CBX1 NOP2 TPD52L2 DNMT1 TUBG1 TACC3 MNS1 TRIM37 DUSP12 NUP85 POLB RAD50 CENPK CKAP5 RRP9 RPL7L1 MCM5 HAX1 RCC1 PDIA4 HAUS4 KLHL7 RFC5 PDAP1 WDR77 INO80E HK2 PGAM1 SPR RPN1 POLR1A CHERP DTD2 DDX41 CYB5B RCN2 MRTO4 LUC7L3 SRM PLK4 HRAS MRPL2 COQ5 GCSH ABCD3 PPA1 TIMM9 CRCP MTHFD2	up	***
GSE27859_MACROPHAGE_VS_DC_UP	0.0000267	0.0003193	0.5756103	-0.3343633	-1.749405	153	NLRC4 SNX10 RAPGEF2 ARRDC4 CALCRL SUSD2 SLC15A3 TET2 IGSF6 CCNL1 RBM7 B3GNT5 PPP1R15B EIF1 TNIP3 MAP3K8 PPP2R2A FAM122A RAB12 MEFV PTAFR SLC12A4 VASP CCL3 NFKB1 ATF3 IRAK2 JAM2 GCA PTCHD4 DSTN SPRYD7 KPNA3 TANC1 KREMEN1 HCK VPS37A CPEB4 HSPA13 MALT1 HIVEP2 TREX1 PIK3AP1 CCR4 TMX3 SMCR8 IFNAR1 TAGAP PLEKHO2 ABL2 RAB5A NLRP3 CCR9 TRAF1 MCOLN2 GSPT1 SPATA5L1	down	***
GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_UP	0.0000196	0.0002452	0.5756103	-0.3336042	-1.749238	166	SLPI GLIPR2 LRRFIP1 FLVCR2 GPCPD1 AGTPBP1 IGSF6 ZEB2 LRRFIP2 ASAP1 MALAT1 RASGRP4 LITAF KLF10 SPI1 ADAMTSL4 ARL11 CASP5 DUSP3 ST3GAL2 OSTF1 VASP MAFG KLF7 PLBD1 ERP44 LAPTM5 SNORA28 FCER1G ARL4A DSE AFF1 RBPJ CREBRF SLC8A1 VAMP3 CPEB4 RAB31 WTAP SORT1 SERPINB1 GNG5 GPR84 RXRA BMP2K ITPRIPL2 UBE2D1 S100A4 GLUL GCNT7 ITCH EGR1 CHP1 USP4 SH3BGRL3 AOAH ZYX S100A8 FPR1 ZFP36 C6orf62 DAPP1 ZBED6 ATP2B4 WDFY2 CFLAR RNF19B CYP1B1 GPATCH2L	down	***
GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN	0.0000659	0.0006891	0.5384341	0.3940975	1.748144	156	TRIP13 BRINP1 CNGA1 MDM1 PMFBP1 BUB1B NUP107 NDC80 PRIM2 GTSE1 ECT2 WDR70 RBBP8 MCM4 SP5 CHRDL2 DTL NCAPD2 STRA6 IDO1 CEL MAD1L1 TPCN1 TEKT2 FAM216B MCM3 ASS1 ZNF786 C7orf50 RAD51AP1 KNSTRN MB KCNE3 POLR3K NPM3 NCAPG SCTR CCDC88C SPAG5 NF1 TACC3 ARF5 DBN1 ATG9B TEKT3 SRD5A3 SAP30 MAT1A ANKRD6 PELO CDK5RAP2 MCM6 ZNF446 IFITM10 CUBN PDIA4 AKAP6 PRR11 MEP1B WDR76 SIGMAR1 UBE2C ADARB2 MSRB1 B3GNT4 PLIN5	up	***
GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN	0.0000148	0.0001904	0.5933255	-0.3290673	-1.747935	177	WEE1 RAB11FIP1 SNX10 CLDND1 TGFBR3 RFTN1 ANXA1 ATP2B1 UBL3 TTYH2 KLF6 STOM GATA3 SRGN CD58 EVI2B AHNAK LIMS1 COTL1 EPS15 RNF139 SLC6A6 GNAI2 DEGS1 GLB1 PHTF2 KLRB1 PHACTR2 IL2RB AQP3 RAPGEF1 GLIPR1 GPR183 TAGLN2 TIGIT GPRIN3 CD74 AKIRIN2 PEA15 DUSP5 ATXN1 LGALS3 CCR6 SLC35D2 CDC42EP3 EPHA4 ARHGAP18 ACTB S100A4 MCOLN2 KIF1B RORA NABP1 IQGAP1 EHD4 RSU1 MIS18BP1 PMAIP1 PIEZO1 HERPUD1 SPPL2A SH3BGRL3 ENDOD1 ITGB1 HLA-DRB1 RNF214 ATP2B4 NCOA7 RNF19B MYO1F MYO5A CBLL1 ADAM19 PLXNC1 TNFRSF1B GZMK IL10RA TANK EZR ZC2HC1A TMEM64 IQGAP2	down	***
GSE1460_DP_VS_CD4_THYMOCYTE_DN	0.0000148	0.0001904	0.5933255	-0.3289844	-1.747495	177	EPAS1 ACP5 LPIN2 CD55 GPR65 SIK1 CD44 LY86 PLEKHA1 S1PR1 BCL2A1 FUCA1 SCN5A PBOV1 SLC7A7 PCYOX1 ASAH1 TMEM204 KLF10 GNG7 SPTBN1 PDE4D ZNF365 PDGFA KDSR ADARB1 ARRB1 CASP1 COTL1 SELL CCND2 CD53 ELK3 SMAD7 TBC1D4 HGSNAT EMP3 ARL6IP5 IL2RB RAB8B CCR7 KLF2 CPA3 EHD1 PDE4B RNF2 JUND BMP2K CPQ WDR1 IQSEC1 TPT1 SP100 ULK2 ABCA8 GPR171 CAMSAP2 THEMIS2 GRB10 IL16 MAN1C1	down	***
GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN	0.0000302	0.0003511	0.5756103	-0.3351818	-1.747266	155	EPAS1 SWAP70 SNX10 CD44 CLYBL MYADM GNPTAB FAM49A ZEB2 GINM1 LRRFIP2 ANXA1 ATP2B1 SBDS C1orf21 MAP3K8 SERPINB9 SRGN BAG1 CST3 AHNAK PSTK PLEKHM3 ITGAX HOPX ID2 CCL4 PRF1 DSTN SMNDC1 INSL6 MTPN GABARAPL2 STAT4 PRKCE COBLL1 TCP1 CST7 SLC25A24 NKG7 KLRC2 PIK3AP1 SMPDL3B GSAP PHF11 ACADL NPTN SERINC3 GEM IL18RAP ING2 SAMSN1 RORA PMAIP1 JDP2 PPP2R3C NR4A2 ICOS ITGAL	down	***
GSE21033_CTRL_VS_POLYIC_STIM_DC_1H_DN	0.0000320	0.0003697	0.5573322	-0.3376864	-1.746684	150	GATA2 COQ2 AQP9 YPEL5 KCNN3 SCARF1 EIF4A1 CD5 LMNA COQ7 CHMP1B BZW1 GLS CRK AKT3 CLK1 BTG3 GPM6A SORBS3 YBX3 PSPN SNIP1 NFKB1 DOCK9 RBMS1 KCNMB1 HPSE LRRC3 DCP1A BCAR3 PPP6C SRSF3 HECA PHF10 LTBP2 JUNB ARHGEF10 HSPA13 REL AGFG1 SLC3A2 AZI2 USP7 ING3 PDLIM1 MEIS3P1 PHLPP2 DOCK6 PITPNA IL18 ARIH1 MEX3C PKNOX2 ITCH NRG1 SFPQ GIMAP4	down	***
GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	0.0000093	0.0001290	0.5933255	-0.3300544	-1.743476	174	GFOD1 S1PR1 OTUD4 IL23A IER2 ANXA1 SH2B3 RRAGC UBL3 NR4A1 PDGFA CSRNP1 MTMR6 LEPROTL1 TMBIM1 DUSP11 PLEKHB2 SMAD7 PLEK RPF1 DSE SLC25A32 IL7R UBASH3B MIR17HG MAPRE2 MYLIP CREM HCFC2 NXF1 NOTCH1 KCTD12 OSTM1 PTGER4 CD83 REL RASSF2 CEBPZ ZNF350 ADNP2 PTP4A1 NIPA2 VAV3 CD6 MAP3K2 TAGAP TMEM70 GPR18 KTI12 SDCBP2-AS1 NBN CDC42EP3 ARIH1 NUP98 EPB41L4A TTC19 MTUS1	down	***
GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN	0.0000278	0.0003295	0.5756103	-0.3319990	-1.740553	171	SASH1 HVCN1 PLEKHF2 RGS9 CALCRL SUSD2 PRPF38A NR3C1 USP47 NUMB EIF4A1 ADAM17 LATS2 SERINC1 KLF6 DACH1 FAM122A CRK AKT3 ZFYVE16 BTG3 PLAUR VASP PDE8A GPR85 ATF3 LBH UBE2B WDR48 NUS1 RUFY3 PIAS1 SACM1L UFM1 CD80 DDHD1 PPP6C NXF1 GABPA ACKR3 PI4K2B RAB8A HSD17B12 CST7 PELI1 MAPK8 SAV1 IFNAR1 STX12 HACE1 LDLRAD4 ARL14EP SRSF10 NFKBIA C21orf91 MT2A BMI1 RABGEF1 PIM3 UBXN8 TBPL1 ATF2 MSANTD3 ATP1B1 SRSF11 MFSD1 UBE3A ALKBH3 ADHFE1 IRF1	down	***
GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_DN	0.0000892	0.0008922	0.5384341	0.3940355	1.739922	149	COL17A1 TRIP13 KCNMB2 GRIK2 FOXM1 IGSF9 NXPH4 MCM10 SLC9A2 PBK BRCA1 GINS1 SLC27A2 FCER2 PAK6 E2F3 TRIB3 CHRDL2 KIAA0895 SMARCC1 ZNF572 KNTC1 KIF2C PFN2 CAPN12 MST1R MTG1 PON1 INCENP EFCAB6 POLR3K UNG TNNI2 PSAT1 POLR1C AK7 ABCA4 NRIP2 LMNB2 HMGN3 ATAD5 CACNG8 NOC4L ADCK1 LRRC46 ALG8 SPAG4 AGMAT SCRG1 SNX7 MAP3K9 PPFIA3 FBN2 ARHGAP11A AGBL5 HOXB2 MXD3 TIMM44 APEX1 NSUN7 E2F7 TRUB2 MRAP	up	***
GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP	0.0000266	0.0003188	0.5756103	0.3870285	1.736921	172	CEP72 AK4 CHEK2 COIL DNAJC12 TBRG4 IFT122 NUF2 RAD54B CDC25A CCNF ASPHD2 SRPK1 C5orf34 CCDC150 GFPT1 HLTF EME1 ODF2 POLA2 KIF2C MPHOSPH9 CHAF1B FAM162A BRI3BP TOPBP1 MAD2L1 DSCC1 RAD18 PPP5C MNAT1 PTPN3 CBX5 RFWD3 GMNN DNA2 MRPL17 FEN1 SEMA3A PA2G4 RNASEH2A HSPA4L POLR2H ILF2 CCNE1 GNPAT ARHGAP11B FAH PSMA5 METTL22 DHTKD1 SASS6 CKAP5 CPSF4 HNF1B AAAS BCL2L1 CDK5RAP2 DNAJC21 PFKFB4 PRMT5 SEC13 NME7 SMC2 ADRM1 DHRS3 ZBTB32 SEPHS1 NCAPD3 MSRB1	up	***
GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN	0.0000349	0.0003968	0.5573322	0.3839594	1.734398	185	TRIP13 HELLS FAM81A NEK2 MPP6 DDIT4 GMPS CDC6 TFDP2 CCNB2 FIGNL1 UHRF1 SPATS2 UMPS GLDC XRCC2 DTL TAMM41 RANBP1 CXCL10 MELK EXO1 PAQR4 BUB1 SMYD2 HOOK1 RAD54L FANCD2 CCDC58 CHEK1 MAD2L1 RAD18 INPP4B BLM FLNB KNSTRN NCAPG2 C12orf75 PLOD2 SLC25A13 PSAT1 FEN1 SPAG5 DIAPH3 RTP4 CENPP NRGN ST14 AKR1E2 KIF22 HMGN3 C9orf152 GAS2 CEP128 ATAD5 CENPK	up	***
GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP	0.0000344	0.0003926	0.5573322	-0.3308676	-1.733727	165	SIRPB1 SMAD6 CD52 PNPLA6 FCN1 CD55 SPN LTA4H FBP1 FIG4 INPP5K PSMD5 TGFBR2 FGR IER2 TXNIP HBEGF SLC7A7 MASP1 HSPB1 ASH2L HMGN1 CCL22 KIAA0513 BST1 CEBPA CDKN1A RRP8 DUSP1 HTT VAMP5 HLA-DQA1 HES1 HCAR3 SGK1 GAS2L1 JUNB GRB2 WDR7 NDUFV2 PPM1F PLCG2 UBB ALDH3B1 PEA15 JMJD6	down	***
GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP	0.0000532	0.0005711	0.5573322	-0.3448205	-1.733259	129	SLC24A4 IL1A TBX3 BMP2 EGR2 CCRL2 FLVCR2 TRIB1 IER2 HBEGF ITGA5 BTG2 FZD4 NR4A1 CD93 SPRY2 ID3 ADAMTS9 ATF3 DUSP1 SMAD7 MAFF SLC25A33 SLC25A25 SGK1 OASL SF3B1 JUN JUNB DUSP8 RCAN1 PPP1R15A FERMT2 FOS LMCD1 FOSB DUSP5 TGFB1I1 ACADL ADAMTS15 MACF1 NR2E3 OPN3 CEBPD EDN1 EGR1 SERPINE1 ACSM5 DUSP6 NR4A2 ARL4D ZFP36 FAM53B PIAS2 AKAP12 TNFSF18 NR4A3 PTGS2 GABRD LRRC18 COL4A2 MFHAS1 CYTIP TNFAIP6 GRM8	down	***
GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN	0.0000344	0.0003926	0.5573322	-0.3307668	-1.733199	165	SC5D ST6GALNAC3 INSIG1 CCRL2 CLYBL SUSD2 NR3C1 IL1RL1 TEX2 SEMA6D ANXA1 BTG2 PBX3 RNF125 NMUR1 GATA3 NR4A1 RGCC MAPK8IP1 TUBB6 AHNAK SCP2 COQ10B MAFG CDKN1A ATF3 ID2 ARL4A CNOT6L CREM NSMAF ARL5B STAT4 KCTD12 PLK3 UHRF2 GPR183 MALT1 COBLL1 TNFRSF9 DENND4A TIGIT FOSB TTBK2 EHD1 MIR23A IRS2 PLSCR4 RGS2 SERINC3 ARAP2 IL18 IL18RAP ITPRIPL2 CCR9 NFKBIA SAMSN1 LDLR TOX2 EVI5 TRIM36 PMAIP1	down	***
GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP	0.0000121	0.0001628	0.5933255	-0.3263787	-1.732306	178	HHEX ZC3H12C LYL1 LMO2 TMOD3 MYADM INPP5A NCF2 FUCA1 CD22 GGA2 ANXA1 SLC7A7 LIFR ENTPD1 GM2A MAP3K8 IFI30 PBX3 LITAF MS4A1 PPP3CA CYP4V2 TUBB6 CD37 PPP3CC TIPARP MPEG1 KLF4 PLBD1 CLIC4 PDE8A EVI2A HCK MTPN PKIG LIMD1 RAB31 KCTD12 CTSZ GSTO1 SNX2 IRF8 PRKCE NDST1 RHOQ TCF4 SBF2 CBFA2T3 LGALS3 CCR1 ACADL IL18 SPIB ALDH2 S100A4 CD19 CTSC DNAJB9 MCOLN2 IQGAP1 RNH1 EVI5	down	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN	0.0000390	0.0004353	0.5573322	-0.3322590	-1.732030	155	OSBPL1A GPR65 EGR2 IBA57 PRPF38A S1PR1 BCL2A1 DENND2C PPM1D PDCL IER2 BTG2 ZNF410 PRSS12 ZBTB8A NR4A1 NFE2L2 ADO EVI2A MIR17HG RASGEF1B C2orf69 CREM CRNKL1 ETV3 ARL5B CYCS PALM PNPLA8 KLHL18 MBNL2 GPR183 KBTBD8 NUDT15 NAA30 HSF5 VPREB3 C4orf36 CNTNAP1 TAGAP GPR18 FAM98B CCNH GEM SLC31A1 TXNDC15 IER5 FBXO30 DNAJB9 LPAR6 PUS3 EGR1 NR4A2 YRDC DNAJB4 CD69 CYP51A1 CHAC2 BCL10 TRMT10C FNIP1 NR4A3 ZNF331 DUSP2 ENPEP FBXO33 CSTF2T	down	***
GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000264	0.0003181	0.5756103	-0.3269318	-1.731927	175	SEMA6A SLC12A6 DENND5A PTPRE LRRFIP1 LINC00472 LMO2 ZCCHC2 ELF2 RRAGC SIRPA NDEL1 MCL1 MTMR6 SRSF5 SDCBP UHRF1BP1L OSTF1 CEBPA DENND3 MAFG ERP44 COTL1 ITGAX ARAP3 FRMD4A TM6SF1 CAPZA2 EVI2A SLC6A6 GNAQ NCOA1 PRCP CYB5R1 PLK3 JUNB IFNGR1 PPP1R15A DAPK2 PSTPIP2 OSM CAP1 RALB PELI1 SLC22A1 FOXO3 SORT1 NAB1 ATP6V0C GNG5 NQO2 ZNF267 SERINC3 BMP2K XKR8 NLRP3 ICAM3 PAK2 DOCK4	down	***
GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP	0.0000277	0.0003294	0.5756103	-0.3294352	-1.730109	164	SEMA3G EPAS1 NLRC4 MGAT3 CD52 GLIPR2 LPXN TRPV2 ARRDC4 GGA2 ADAM17 ABCG2 PARVG ANXA5 MS4A14 C1orf162 ADARB1 KLF11 VASP STK17B TLR4 GNAQ IL7R NCOA1 PRCP TECR CABLES1 AQP3 ETS1 KLHL18 SIGLEC15 NPR1 SNX1 CD151 LMCD1 SIGLEC1 PNPLA3 TGFB1 TSC22D1 ANKRD13A FCGRT DECR1 EGFL7 CALHM2 IQSEC1 PIP4K2A OSER1 LTBP3 TOMM5 EHD4 DISP1 SVIL KCNE1 ATP11B	down	***
GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP	0.0000187	0.0002350	0.5756103	-0.3281434	-1.729703	172	CXCL3 CD300LF CPEB2 LIPA EGR2 MYADM PLEKHA1 STX11 CD9 TRIB1 SPCS3 ZEB2 SEMA3B SLC7A7 LIFR EIF1 LITAF HDC HIPK3 GLS SIRPA TIPARP IL10 TBC1D9 AHNAK PDE8A CXCL2 VIM ID2 CCND2 UBASH3B STK24 SERTAD2 JUN RAB31 PTGER4 STX7 PSTPIP2 OSM TAGLN2 YPEL2 NIPA2 TCF4 DUSP5 CD86 PIM1 CCR1 GEM CCR9 MCOLN2 NR3C2 GIMAP4 RNF13 DMXL2 CSF2RB SLC38A2 CD69 SORCS2 FXYD5 SPTY2D1 GPR137B	down	***
GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP	0.0000276	0.0003292	0.5756103	-0.3262687	-1.728414	175	ACP5 MS4A7 DCSTAMP PID1 ENG LY86 CORO1C ACER3 GGA2 PDE2A EDEM1 WWC2 CD33 LIFR SLC7A11 DENND6A PXDC1 KLF7 FMNL3 MGAT4A ATF3 CCL4 ARAP3 FCER1G IL7R GLB1 ST6GALNAC6 SLC25A33 CTSS MAGI2 C1QA STAT4 HRH1 RAC2 TYROBP ACKR3 GPR183 NDST1 TIMP2 RELL1 GPR84 DOK2 ACYP2 ETS2 ARAP2 SCPEP1 EDN1 B3GNT2 DLST KIF1B HTRA2 C1QB CX3CR1 DRAM2 PLXDC2 MTSS1 PDE7B MAN1A1 FCGR3A PDPN PTGS2 IRF4 SRXN1 SLC29A3	down	***
GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN	0.0000140	0.0001827	0.5933255	-0.3270461	-1.727585	174	ADPRH DENND5A FYN CD44 BMPR2 AGTPBP1 TET2 TEX2 HBEGF REV3L RGCC TRAF6 CSRNP1 FOXO1 SPAG9 MGAT4A NFKB1 SELP CD53 EPS15 MBD2 RAP1GDS1 IL7R TP53BP2 AFF1 IL24 ANXA3 BTG1 GPBP1 RYBP SOCS3 UTRN LYRM1 OSM PTGER2 COBLL1 ZNRF3 AP3B1 RRAS CDK17 ZC3H12D GALC PIM1 TMEM107 NRN1 GTF2B BMP2K ANKLE2 MIER1 YAF2 TMEM184B SSH2 FDX1 DOCK10 LYST CAMSAP2 NABP1 ICOS DCUN1D3 SH3GLB1 DRAM2 HEY1 POLI MAN1A1 ITGA6 FNIP1 DUSP22 NR4A3 CCNC IRF4 AKAP13 RNF19B	down	***
GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_DN	0.0001146	0.0010948	0.5384341	0.3923675	1.726728	145	BBOX1 PTPRT SPICE1 CDH17 SPOCK1 PARPBP DGCR5 BRCA1 METTL1 SPP1 TPX2 CDC25A LIME1 CDT1 MANSC1 ITGA2 EXO1 EMC9 DPY19L1 APOL1 RAD54L SARS2 KDELR2 GAS8 EHHADH PKMYT1 TSHR PLA2R1 PSRC1 ASF1B CDK1 PDK1 SPAG5 G6PC3 ALDH7A1 PKP3 BTN2A3P POLD1 KDELR3 CLINT1 ASRGL1 DYNC1LI2 IGHMBP2 B9D1 RCN3 HDLBP ARSA PCSK5 GTF3C5 IGLV3-19 UBE2C COPZ2 FOLH1	up	**
GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN	0.0000114	0.0001540	0.5933255	-0.3257005	-1.725502	186	USP12 RBMS2 SNX10 SPNS1 GIMAP8 PTPRE CALCRL INPP5A CCNL1 PDE2A GINM1 CHMP1B CYB5A HLX GPBP1L1 CRK UBE2D3 ATP6V1H ATP10A PPM1K CASP1 COQ10B UHRF1BP1L SELL PIK3C2A KLRD1 MBD2 UBASH3B C16orf54 SLC25A33 PPIL4 CREBRF ETF1 S1PR4 SENP3 CD160 SNAP23 PLEKHA3 STAT4 RHOBTB2 KCTD12 UBAC2 KBTBD8 YWHAZ CEBPZ RNF146 AZI2 PPTC7 HBP1 ANKRD13A KTI12 PITPNA GLTP C3orf38 SEC63 VPS4B TRAPPC8 ESYT1 TBC1D1 G3BP2 SDAD1	down	***
GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN	0.0000233	0.0002834	0.5756103	-0.3306711	-1.725356	168	KMO LPIN2 IL1A ADPRH BACH1 QKI MYD88 ZCCHC2 GTF2I ARL8B GIMAP6 SCARF1 IGSF6 IER2 CCNL1 RBM7 TXN BAG1 CASP5 IL10 PLAUR CLIC4 CCL4 CCSER2 INHBA N4BP1 C4BPB AFF1 USP25 HCAR3 OASL SERPINB8 DHX15 CCR7 COBLL1 NDUFV2 ACSL1 AGFG1 CD164 PIM1 GNG5 KCNA3 SOD2 STX12 GATA6 PDE4B GEM ICAM1 IL18RAP TNFAIP8 NBN HSP90AA1 NLRP3 TRAF1 B3GNT2 GPR171 LDLR MT2A GIMAP4 EHD4 TRIM36 PMAIP1	down	***
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN	0.0000222	0.0002740	0.5756103	-0.3247433	-1.724967	177	SLC24A4 EPAS1 ACP5 HHEX FABP4 MNDA CLEC3B KL LY86 CLEC10A AVPI1 DPEP2 CARD16 ASAH1 GNGT2 ECHDC1 M1AP RB1 GRN APOC1 SORBS3 CYBRD1 CFD DUSP3 AHNAK CPVL SLC7A8 ZADH2 TPP1 LINC00324 BACE1 SPIN1 CCNY CTSS SNX29 DDX17 BTD PIK3R1 MBNL2 SIGLEC15 OGFRL1 GAS2L3 FXYD6 ITGA9 CD1D ZBTB1 FAM228B BAZ2B EXOC1 VPS39 PLA2G15 IST1 CEBPD PIP4K2A SLC2A9 METTL7A NHLRC3 LPAR6 CNOT8 SPOPL MIS18BP1 SLC35A1 STARD13 ATP6V0A1 HERPUD1 NR4A2 C5 TREM2	down	***
GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN	0.0000755	0.0007796	0.5384341	-0.3382576	-1.724681	138	FCN1 BAG4 FLVCR2 IL1RN CD36 CD33 ENTPD1 EIF1 ADIPOR1 SLC25A37 CD93 GRN SPI1 ZMIZ1 CYBRD1 PTGIR DUSP3 PPT1 SDCBP BST1 KLF4 PLAUR TPP1 PLBD1 CTBS CD302 PLEK GNAQ VAMP3 CTSS PGD SOCS3 SERPINB8 IFNGR1 GRB2 DEDD ACSL1 FOS SORT1 TIMP2 SERPINB1 APLP2 LGALS3 CTIF STX12 TSPO BNIP3L GPX3 CHMP3 MS4A4A GLUL DAZAP2 WDFY3 EGR1 CSF2RB CRTAP ZYX S100A8 FPR1 QSOX1 CYP51A1 TRIM25 RAB1A CCPG1 RNF19B CYP1B1 MYL9 GSN HBS1L	down	***
GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP	0.0000565	0.0006048	0.5573322	-0.3429554	-1.723884	129	IL1A TBX3 GPR65 EGR2 CCRL2 TRIB1 IER2 HBEGF BTG2 LITAF NR4A1 CD93 SPRY2 RHOB IL10 KLF4 COQ10B CXCL2 ATF3 DUSP1 PIK3C2A MAFF SLC25A33 SLC25A25 CD80 PRDM11 IL6 DDHD1 SGK1 JUN PLK3 JUNB RCAN1 PTGER4 FOS SPRY4 RBKS FOSB DUSP5 LRRC32 RGS2 GEM CEBPD EDN1 NRG1 MT2A PMAIP1 EGR1 SERPINE1 DUSP6 NR4A2 KIAA2026 ARL4D ZFP36 ADAMTSL3 AKAP12 HMGB1 TNFSF18 NFIL3 NR4A3 PTGS2 IMPACT NFKBIZ DUSP2	down	***
GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN	0.0000241	0.0002923	0.5756103	-0.3300315	-1.722019	168	CD52 PDLIM2 FYN LY86 WDR74 MYD88 ZCCHC2 INPP5A YPEL5 MSRA FRAT1 TGFBR2 HPS5 GGA2 LCP1 ATP6V1H STK17B MAP1LC3B LAPTM5 RBMS1 SELL LBH CD53 ALOX5AP SNN PKIG METAP1 WASF2 CDC40 INPP5B RNF141 PIKFYVE CD48 HMBOX1 CD83 RASSF2 TNFSF13 BTBD7 DCK TGIF1 PHF11 PIP4K2A RIPK2 SP100 OSER1 CD19 JMJD1C DOCK10 PAK2 DLST CCND3 IL16 BANK1 FNBP1 ARHGEF18	down	***
GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP	0.0000383	0.0004289	0.5573322	-0.3275387	-1.719629	167	KLF13 HSD17B11 KIAA1109 INPP5A NEDD9 AGTPBP1 FRAT1 IER2 TOE1 TNFRSF8 KLF6 CD93 CLK1 EPM2AIP1 MCL1 CFD SRSF5 SAP30BP CASP1 KLF4 CPVL DENND3 PTPRC SELL CLK4 DUSP1 WDR48 EVI2A S1PR4 NXF1 JUNB CSTA PPM1F PELI1 KLF2 ICAM2 ING3 CD1D CBFA2T3 RGS2 HELZ SEMA4A CEBPD SIK3 NLRP3 ICAM3 FNBP4 LYST DAZAP2 IL16 MIS18BP1 SETX DUSP6 CX3CR1 CRBN ING1 ZFP36 MTSS1 DAPP1 SECISBP2 DUSP22 JARID2 ARGLU1 MYO1F CRLF3 TNFRSF1B IL10RA PNISR PELI2 C15orf39 SYF2 VNN2 STK10	down	***
GSE3982_DC_VS_NKCELL_UP	0.0000242	0.0002930	0.5756103	-0.3237017	-1.719434	177	GPD1 SLC31A2 KMO SLC47A1 TAL1 PPARG CAT CCDC88A FCER1A FOSL1 CYB5R3 ALAS1 CD9 IL1RN LAMP1 SCARF1 IGSF6 GM2A ANPEP HLX ABHD6 RGCC TNS1 SLC19A1 ATP6V1H CCL22 DRAM1 CDKN1A ATF3 ARL4A FKBP15 MMP19 CLN8 SGK1 ESD SLCO2B1 MITF RAB31 CTSZ PODXL PABPC4 CD83 NPR1 PSMD12 PEA15 CTNNAL1 MCUR1 LRRC32 UTP3 LGALS3	down	***
GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN	0.0000230	0.0002822	0.5756103	-0.3241361	-1.718793	181	ACP5 RAMP3 SWAP70 HVCN1 GPR65 CALCRL IDI1 SLC15A3 GIMAP6 AGPAT4 EDEM1 CLCF1 HBEGF SBDS SGMS2 ADAM17 MAP3K8 KLF10 NFE2L2 TUBB6 SLC7A2 IL10 RAB12 REST PNRC1 N4BP1 MAPRE2 PROCR RPS6KA2 RNF149 SYNPO2 SOCS3 OASL ARL5B ST6GALNAC4 HSPA1B JUNB ATP11A EEA1 GPR183 DENND4A CDK17 UBXN2A VAV3 TGIF1 DUSP5 IFNAR1 STK40 GNA13 PLEKHO2 GTF2B RNF2 CTTNBP2NL SETDB2 IQSEC1 RIPK2 RASSF8 ADORA2A KIT NRP2 SPATA13 PAPSS2 CSF2 SUGT1 CD70 CDC14A CX3CR1 OSGIN2 HLA-DRB1 DAPP1 UBE2N RCSD1 CSF3 SH3BP2 PDPN NR4A3 NCOA7 EBI3 ST3GAL1 TNFRSF1B SLAMF7	down	***
GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN	0.0000452	0.0004927	0.5573322	-0.3278989	-1.718171	165	RAB11FIP1 GCOM1 ARHGAP31 OLR1 ZC3H12C LRRC8C SNX10 MIR22HG INSIG1 TMEM170B HCAR2 CALCRL ATF7IP2 SIRPA NDEL1 NODAL PTPN12 REST PLEKHM3 ZFAND5 VASP KLF7 NFKB1 IRAK2 AQP4 CCL4 DUSP1 PLEK SH2D2A N4BP1 PIK3R5 KPNA3 MAFF RASGEF1B FAM102B SOCS3 MITF CPEB4 NXPE3 FOXN2 WTAP MALT1 REL EHD1 CRY1 PDE4B ETS2 ICAM1 CEBPD NLRP3 MEX3C NFKBIA KIT ZDHHC5 TNFSF9 SAMSN1 GSPT1	down	***
GSE7219_WT_VS_NIK_NFKB2_KO_DC_DN	0.0000397	0.0004414	0.5573322	-0.3279026	-1.716848	160	CD55 SPN CLDND1 LRRFIP1 PPP4R1 AQP9 S1PR1 ELMO1 GNPTAB NFATC3 FAM49A PDE2A ATP2B1 CYP17A1 B3GNT5 GM2A C1orf21 ECHDC1 FOXP1 LAIR1 IL18R1 CRTAM PSTK ZSWIM6 SELL CD302 PLEK PPP2R5C IL7R PIK3R5 MOB3A CNOT6L UTRN SH3BP5 CD7 TAGLN2 KLRC2 XYLT1 BIN2 SMPDL3B PDLIM1 ZC3H12D CLDND2 EXOC1 MACF1 ME2 IL18RAP SP100 GPD1L CCND3 SMAD4 ARHGEF18 SETX TNFSF8 ATP11B	down	***
GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN	0.0000198	0.0002467	0.5756103	-0.3234560	-1.716581	176	DENND5A RAPGEF2 CCRL2 MYD88 CIR1 RBM14 ALAS1 CDC42 MARCO BCL2A1 RFTN1 PLA2G7 DNAJC3 HBEGF CYB5A LITAF LCP1 STOM PDE4D TFRC TXN CASP5 MAP2K3 PLAUR DENND3 GMPR CCL3 RIT1 ATF3 DUSP1 INHBA VAMP5 N4BP1 CRIM1 FLT1 OASL CD48 SH3BP5 DNAJA1 RCAN1 PPP1R15A WTAP CCR7 IFRD1 CD83 CXCL5 PPP2CB TESK2 DUSP5 PIM1 KYNU ANKRD12 GEM ICAM1 SLC31A1 NBN	down	***
GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP	0.0000360	0.0004068	0.5573322	-0.3239407	-1.716081	175	EPAS1 CD101 OSBPL1A HHEX FABP4 CLEC3B CAT LY86 CLEC10A TBC1D2 CD9 AVPI1 TXNIP DPEP2 PCYOX1 GRN CYB5D2 APOC1 SORBS3 FABP5 CFD PPT1 CPVL SLC7A8 ZADH2 CEBPA KLF7 LINC00324 CADM1 NR1D2 CD302 BACE1 CD300LB MAPRE2 CNRIP1 RPS6KA2 PDK4 SPIN1 CCNY SGK1 SNX29 PABPC4 SIGLEC15 OGFRL1 WDR7 GAS2L3 ECI2 SPOP FAM228B LGALS3 GNA13 PLA2G15 SESN1 HAVCR2 METTL7A ING2 ACADM STARD13 HERPUD1 PHYH CRTAP TREML1 EIF3L TREM2 PLEKHA2 KCNJ1 ATP1B1 HLA-DRB1 ABHD14A METTL25	down	***
GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN	0.0000122	0.0001634	0.5933255	-0.3222154	-1.714794	184	TMEM126A U2AF1 RCOR1 ST3GAL6 GTF2E2 PRPF38A NEDD9 BCL2A1 CD9 PTS ASAH1 LITAF CYP4V2 AHNAK CASP1 YBX3 RRM2B ITIH5 NFKB1 ID2 ARAP3 EVI2A CPT1A KLRD1 TM9SF2 IL7R MAPRE2 CREBRF CD160 KCTD12 TYROBP SHOC2 GSTO1 EEA1 DAPK2 CREB1 RAB8A SNX1 CST7 OCIAD1 SNX9 GRSF1 RHOQ CHPT1 TCF4 TGIF1 PDS5B VAMP4 TSC22D1 GABARAPL1 ACADL DECR1 RGS2 ARPP19 TFPI OSER1 KIT B3GNT2 CHCHD7 MCOLN2 DAZAP2 RHOT1 GIMAP4 EID1 KLC1 HERPUD1 PHYH	down	***
GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP	0.0000446	0.0004885	0.5573322	-0.3270425	-1.714568	171	HHEX RAPGEF2 THBD SIK1 CTSW ST3GAL6 VAMP2 MAL HEG1 TXNIP TOE1 EIF1 BTG2 LITAF CLK1 SORBS3 TIPARP MOAP1 LEPROTL1 TPP1 LAPTM5 RRP8 UBE2B PER1 IL7R PLCD1 NCOA1 BTG1 KCNA5 AREG CD48 JUNB DUSP8 CCR7 DDX5 YWHAZ SRSF6 ZBTB1 HBP1 GABARAPL1 TOB1 PDE4B JUND RBL2 CXCR4 IFFO1 RPS13 CYTH1 EIF4A2 ARHGEF18 CDC14A LHFPL2 HAS2 TUBA1A TSC22D2 MATR3 CHKA FCHSD2 RANBP2 TERF1 PNISR FASN HOXA5 EPHB6 RPL32 JOSD1 PADI2 PYGM RPS15A USP34 VIPR1 CD59	down	***
GSE3982_NKCELL_VS_TH1_DN	0.0000478	0.0005179	0.5573322	0.3806648	1.713983	180	ABCC2 HELLS NEK2 GGCT DEPDC1 PHGDH E2F8 CENPA PTTG1 ESPL1 SFXN1 TPX2 CCNB2 CDC25A GINS4 AURKA NUP155 KIF2C RRM2 PDCD5 KIF11 SMYD5 BLM TST SYMPK NOL3 SPRY1 PARP1 CASP6 CKS1B NCAPG2 TMEM106C POLE2 BIRC5 GMNN POLR3K NCAPG STEAP1 PSMB5 RECQL4 QPRT SNRNP25 TUBG1 EFCAB2 DBN1 IL15RA GINS2 KIF20B LRRC20 ENPP2 TCEA2 CKAP5 PELO MCM5 GLO1 MSH2 FAM3C PRIM1 RAD51 N6AMT1 LRRC8B OXCT1 NME7 TNS3 SMC2 POP4 PAICS UBE2C BCAT2 OAS3	up	***
GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP	0.0000288	0.0003401	0.5756103	0.3806269	1.712776	179	KIF20A FAM81A CDC45 BUB1B POLQ MND1 TTF2 PIF1 GTSE1 TRAIP MSTO1 FLAD1 PAK6 TPX2 SMPDL3A PRC1 CCNF DTL MCM8 LIME1 NCAPD2 MELK EXO1 PAQR4 PAFAH1B3 AUNIP EXOC4 BRI3BP AHCY RAD51AP1 ABCB9 SPC24 PERP BRIP1 PML ERCC2 KNSTRN RNF216 DCLK1 CBX5 ASF1B STON2 CENPH ARPC1A ADAP1 DNA2 AP5Z1 SAPCD2 RTP4 ABHD4 SERHL2 SLC37A4 FHL2 CENPK DHRS1 POPDC2 NEK4 PYGO2 HMCES IL12RB2 B9D1 SHCBP1 LPGAT1 CARHSP1 MXD3 VDAC3 UQCRQ LIF UBE2C COX6B1 NUP93 CYP11A1 TEX9 LYPLA1	up	***
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP	0.0000193	0.0002419	0.5756103	-0.3239084	-1.711010	174	SC5D FCN1 CD101 HHEX FBP1 DCSTAMP LPXN LIPA TMEM170B SAMHD1 GFOD1 RASAL2 NCF2 CD9 AVPI1 TXNIP CD36 NCEH1 CLEC7A CAMTA1 ABHD6 RGCC SPRY2 PPT1 KIAA0513 ADO KLF9 LAPTM5 PAPSS1 TM6SF1 EVI2A RAP1GDS1 UBASH3B CD300LB PRCP RBPJ PGD MITF MALT1 LPCAT2 VMO1 FOS TGFB1 GABARAPL1 DECR1 GNA13 PLA2G15 ARHGAP18 TBC1D1 SCPEP1 CD1E DOCK10 CAMSAP2 ENY2 HAT1 DISP1 GREM1 SERPINE1 C5AR2	down	***
GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_UP	0.0000309	0.0003579	0.5573322	0.3804233	1.709636	176	CEP89 NUP107 CCDC34 PSPH PBK KIF18B TTF2 DEPDC1B E2F8 GTSE1 KCNQ5 RAD54B TYMS MCM8 SHMT2 TAMM41 RANBP1 CISD1 KIF23 MKI67 FANCA TOP2A CENPL E2F2 RRM2 SMYD2 CDCA5 MRPL27 SMYD5 ZNHIT1 AHCY DSCC1 KNSTRN CBX5 C1orf112 NUDT2 GMNN SEC61G NUP205 MZT2B LMNB2 DTYMK MYBBP1A MFSD2A GINS2 DAP3 FUCA2 C12orf73 NUP85 DCUN1D5 MRPL41 NMNAT1 SNRPD1 LANCL2 KATNB1 POLR2I ETV6 CCNA2 SMARCA4 PRIM1 HDLBP RNF157 MRPL21 NDUFS8 CISH NDUFB7 ZNF367 PPP1R14B NCAPH GEMIN2 TEX9	up	***
GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN	0.0000481	0.0005186	0.5573322	-0.3255469	-1.709171	167	LPXN PID1 CD44 CTSW ST3GAL6 MYADM STX11 BCL2A1 PEAR1 ABCB1 PDE2A ATP2B1 B3GNT5 ZDHHC2 PRSS12 IL18R1 GRN PPP3CC NRARP AHNAK CASP1 YBX3 GAA OSTF1 PDE8A CDKN1A ID2 MATK IL7R MAPRE2 IL2RB RAB8B NDNF ATXN1L PTGER2 TBX21 CST7 GPRIN3 NKG7 SMPDL3B ZC3H12D TBRG1 C8orf37 SPOCK2 SYT11 IL18RAP EPB41L5 CDC42EP3 HIGD1C TRAF1 HES2 S100A4 METTL7A ADORA2A RORA GSG1 TOX2 JDP2 ENDOD1 ICOS ITGB1 SLC26A11 MICAL1 ABHD14A	down	***
GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_UP	0.0001166	0.0011086	0.5384341	-0.3271150	-1.709024	154	EREG KMO USP12 RAPGEF2 INSIG1 BACH1 AQP9 CDC42EP2 STX11 BCL2A1 FAM49A TOE1 TRA2B RRAGC BTG2 MAP3K8 PTX3 NR4A1 JAM3 AKT3 CNN1 PRDM16 TPSG1 VASP CLIC4 DNTTIP2 MAFF AKIRIN1 SNN NINJ1 KANK1 PPP2CA PSEN1 PPP1R15A WTAP PODXL TAGLN2 TOM1L2 TPRA1 IP6K1 ACSL1 GPR37L1 CDK17 ICAM2 SOD2 IST1 RNF2 ANKLE2 TNFAIP8 RAB5A CALCOCO2 NUP98 RPS13 KCNK7 TLK2 ATF4 DNAJB5 ARFGAP3	down	**
GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN	0.0000218	0.0002698	0.5756103	-0.3233149	-1.707876	174	OSBPL11 PRKG2 SNX10 ENG KL PRPF38A PDCL RBM7 PCYOX1 IFI30 ANXA5 ZEB1 TMEM38B ATP10A TIMM10B BNIP2 AGR3 ARC PNRC1 N4BP2L1 PPP2R5A RABGGTB MCMBP DDHD1 HSD17B13 PGD PLEKHA3 ETV3 NOTCH1 DDX17 APBB2 SNX2 IRF8 NAA30 TPRA1 MOB1A MBP EMC7 STXBP3 PARD6A NAB1 GALC WBP2 CTTNBP2NL MGAT2 IQSEC1 CXCR4 RIPK2 G3BP2 KATNA1 FNBP4 KLRK1 SKI THRAP3 C1orf52 ZFAND2A UBXN8 CHIC2 CLEC4E PRKCH TRMT1L DRAM2 KMT2E RNF167 GNG11 SNX14 CAPZA1	down	***
GSE17721_12H_VS_24H_LPS_BMDC_UP	0.0000420	0.0004626	0.5573322	-0.3223698	-1.707760	175	SGK3 ZC3H12C PRKG2 TMOD3 MYD88 PRPF38A MKNK1 FGR CCNL1 KCNAB1 ABCG2 KLF10 KLF6 PPP2R2A ARHGEF2 ITSN2 KIF1C CCL22 RAB12 BNIP2 DENND6A SLC7A8 VRK2 RBMS1 UBE2E2 PTPRC GPR85 ATF3 ELAC1 PLEK SPRYD7 FKBP15 MAPRE2 NRROS RPS6KA2 IL6 NEK7 NXF1 SERPINB6 MORC3 PXK SLC3A2 SAV1 GPR84 APLP2 PDLIM5 WDR1 ALDH1B1 IER5 PLGRKT KATNA1 NFKBIA	down	***
GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP	0.0000297	0.0003476	0.5756103	-0.3214550	-1.707500	177	SEMA6B SWAP70 OLR1 PHACTR1 PPP4R1 CD9 HEG1 PDE2A SH2B3 LMNA PKD2L2 EIF1 SERINC1 AKT3 SPTBN1 TLE4 AGO3 SAP30BP CADM1 TAF9 IL7R PAFAH1B1 AKIRIN1 CDKN2AIP MMP19 TDRD7 EMP3 SAR1A ESD RAB8B RHOG FERMT2 PODXL UNC13B RNF24 YWHAZ CGGBP1 TPRA1 AMD1 MOB3B OPN3 B3GALNT1 SNX15 ITCH NRP2 IQGAP1 SFPQ GSPT1 PAPSS2 HTRA2 SSB ZNF654 DNAJC8 KIDINS220 GABPB1 ACTR1A EP300 TRIM25 SH3BP2 UEVLD MPDZ KRT10 HS3ST2 CYP1B1 APOBR CBLL1 MFHAS1 PPP2R5B TRNAU1AP BCAP29 TOP1 PLEKHM2 S100A10 CDC27 IL1R1 VEZF1 SLC25A44	down	***
GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN	0.0000226	0.0002781	0.5756103	-0.3230696	-1.706580	174	GLIPR2 DPYSL2 RGS9 CALCRL OTUD4 USP47 CCNL1 RBM7 FAM89A ZNF503 DACH1 FAM122A ZFYVE16 TXN ATP10A PLAUR OSTF1 THBS1 ST7L GPR85 PAPSS1 CLK4 WDR48 NUS1 EFR3A KREMEN1 PIAS1 TDRD7 USP25 UFM1 CD80 PPP2CA INO80C NXF1 GABPA ATP6V0B GMFG MORC3 TPP2 TMEM128 MAPK8 SPOP EMC7 AZIN1 ZBTB1 KCTD10 TSC22D1 FEM1B YTHDF2 CNOT7 HNRNPH3 GEM EPHA4 ARL14EP TBC1D1 LYSMD3 NFKBIA KLRK1 COL13A1 PPP1CB PIM3 CFL2 BHLHE41 TBPL1 SPPL2A	down	***
GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_UP	0.0001653	0.0015256	0.5188481	0.3860884	1.706170	152	SPATA24 CHEK2 NEK2 CCDC34 TIMELESS UBE2T DEPDC1 CDK4 RACGAP1 IFT27 ESPL1 E2F3 FIGNL1 UHRF1 GINS4 SPDL1 TAMM41 DNPH1 KNTC1 BUB1 NUP155 POLA2 POC1A CDCA5 WDHD1 LIG1 ORC6 MAD2L1 DSCC1 RAD18 NCAPG2 CDKN2C NSF GMNN PSMB5 GNPNAT1 PSAT1 NEIL3 TAF6 RANGAP1 NMRAL1 MNS1 TUBB2A TK1 ANP32E CEP128 TDP1 LANCL2 GINS3 ALG8 ECH1 UQCRC1 CCDC181 CHMP2A NDUFS8 VDAC3 SWI5 PPIA COX6B1 KIF24 TRPC4AP ACSL5	up	**
GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP	0.0000591	0.0006260	0.5573322	-0.3240792	-1.705665	169	CLEC1B HSPB7 OLR1 TUBB1 SH2D3C LDB2 STX11 ALAS1 NEDD9 IL23A CCNL1 SGMS2 HECW2 ENTPD1 KLF10 SLC7A11 SLC25A37 SPRY2 ITSN2 PTPN12 SNED1 SORBS1 BST1 USP2 FMNL3 UBE2B CD53 PLEK N4BP1 RASGEF1B PIAS1 BTG1 NINJ1 MYLIP ATP6V0B CNTN4 SKIL MPZL3 ZNF597 ACSL1 PELI1 PRKCG PIK3AP1 NAB1 PIM1 TAGAP XKR8 IQSEC1 SIK3 SSH2 GRIN3A LYSMD3 MTUS1	down	***
GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP	0.0000231	0.0002832	0.5756103	-0.3213141	-1.705424	178	SWAP70 SNX10 CAT FYN LY86 QKI ZCCHC2 SRSF7 VAMP2 MKNK1 CD1C CD22 FGR GGA2 KIAA0355 ENTPD1 ATP6V1H ATP6V1B2 SRSF5 DENND3 LAPTM5 GCA RAP1GDS1 TBC1D4 MAPRE2 SNN STK24 RPL17 USP25 PKIG MYLIP FRY CDC40 PHTF2 SNAP23 PIKFYVE PDCD6IP STX7 DDX5 MORC3 REL UVRAG SLC25A24 AGPS MYL12A VAV3 TSC22D1 KYNU PPID RBL2 TRAC TNFAIP8 ZBTB25 ARPC5 PAK2 LYST PDE8B AIM2 DAZAP2 CNOT8 SMAD4	down	***
GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN	0.0000781	0.0008009	0.5384341	-0.3390387	-1.704196	129	RAB11FIP1 ZC3H12C MIR22HG GFOD1 B3GNT5 NR4A1 CLK1 MAPK8IP1 RHOB CSRNP1 IRAK2 ZBTB43 CLK4 TP53BP2 SLC25A33 CREBRF HCAR3 AREG CREM DNAJC27 ETV3 PTGER4 OSM KBTBD8 GRASP MFAP4 HOMER1 DENND4A PELI1 FOXO3 TGIF1 IRS2 RIMKLB RGS2 PDE4B GEM ABL2 MIR155HG DDX59 TMEM217 TRAF1 TTC32 FNBP4 MAFK ZNF165 PURB PMAIP1 DCUN1D2 PIM3 NR4A2 SLC19A2 EFNB2 PATL2 DNAJB1 TPSD1 IRF1 SIRT1 NR4A3 PTGS2 METRNL IVNS1ABP ZCCHC14	down	***
GSE3982_EOSINOPHIL_VS_TH1_DN	0.0000293	0.0003441	0.5756103	0.3798222	1.703817	173	FOXM1 CEP72 RUVBL1 ELOVL6 APOLD1 METTL1 PTTG1 TYMS CAND1 SHMT2 CCT2 NME1 LDHB KNTC1 EEF1E1 PUS7 APOL1 VANGL1 ZNHIT6 ABCB6 KDELR2 PHB TST ERCC2 CNPY2 PLOD2 ASF1B BIRC5 AAGAB GOLGA8A MRPL17 NEIL3 SPAG5 METTL3 PA2G4 RNASEH2A RANGAP1 SNRNP25 DNMT1 DNAJA3 ATP9A DPH2 GINS2 MRPL4 AGPAT5 KIF20B DAP3 ASNS COPS6 FN3KRP PFAS BAD MRPL24 UBE2V2 MRPS33	up	***
GSE17721_0.5H_VS_8H_CPG_BMDC_DN	0.0000290	0.0003408	0.5756103	-0.3232297	-1.703802	172	SASH1 MS4A7 DENND5A C18orf32 NUP54 OSCAR CAV1 IDI1 PRPF38A DSCAML1 PILRA ABCB1 RBM7 ANXA1 SERINC1 COX18 ZBTB21 TOR1AIP1 CLK1 ZEB1 CASP1 SLC7A8 RMDN3 CLIC4 ELK3 MBD2 MPC1 MTPN MOB4 ARL6IP6 TREM1 DNAJA1 ENPP4 LYRM1 PRKCE CREB1 REL PHOSPHO2 PSMD12 CCR4 UBXN2A HBP1 ICAM1 ARAP2 SLC31A1 SFT2D1 EPHA4 ARL14EP TBC1D1 KPNA4 TLK2 THEMIS2 PPP2R3C SERPINE1 TNFSF8 CLIP1 SLC38A2 FAM8A1 DRAM2 DYNC1I2 EYA3	down	***
GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN	0.0000328	0.0003790	0.5573322	-0.3207016	-1.703498	177	GCOM1 PECAM1 HSD17B11 EGR2 INPP5K GPCPD1 VAMP2 DYRK1A MKNK1 NR3C1 PDE2A NUMB SLC44A2 UBL3 EIF1 RAB33B GNGT2 BTG2 RANBP9 FOXP1 GLS ADRB2 NFE2L2 MAFG KLF7 FAM49B CDS2 CEP57 GNAQ TAF13 AFF3 RPL17 PIKFYVE NXF1 VAT1 ZFP91 KCTD12 ETS1 IFRD1 UBAC2 RHOQ AZI2 HIVEP2 SRSF6 DUSP5 TOB1 SERINC3 LAT SFT2D1 ING2 STK4 CEPT1 ARPC5 SCAI SKI CYTH1 SPATA13 ARHGEF18 LNPEP TUBA1A RNF167 SRSF11 BCL10 RCSD1 STX16	down	***
GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN	0.0000450	0.0004910	0.5573322	-0.3242055	-1.702643	164	ADTRP C18orf32 HCAR2 PLEKHF2 GTF2E2 GPCPD1 SLC15A3 STX11 IL23A LYRM4 ENTPD1 MTF1 PICALM HDC PAG1 PPP2R2A FAM122A IL18R1 NDEL1 CLK1 MCL1 FLI1 CPED1 SNAI1 FMNL3 PTPRC CDS2 IRAK2 CD300C N4BP1 LRRC3 CMTM6 HGSNAT NXPE3 IFNGR1 SKIL EEA1 UBAC2 CREB1 PTGER2 PXK ASTE1 ADNP2 CDK17 ETS2 IFNLR1 PDLIM5 IL18RAP RLF THAP6 G3BP2 GRIN3A KATNA1 MTUS1 MACROD2 SUGT1 CNR2 ITGAL TRMT1L S100A8	down	***
GSE24210_RESTING_TREG_VS_TCONV_UP	0.0000266	0.0003188	0.5756103	-0.3204708	-1.700738	176	SLC12A6 KLF13 HHEX CYP27A1 ARRDC4 MYADM C8orf58 MANBA SPATA1 GIMAP6 SYS1 CD22 ANXA1 CNST SH2B3 RAPGEF4 NAAA CYB561A3 TMEM123 ZEB1 EVI2B AGO4 ARRB1 MTMR6 CCDC82 ITM2B ROCK1 PTPRC MRVI1 AFF3 FRY MTMR14 CPEB4 JAK1 RAPGEF1 FRYL COBLL1 AP3B1 PXK KLF2 YPEL2 CD164 AZI2 NAPG KYNU SERINC3 UNC13D SESN1 SLC35D2 CHURC1 CDC42EP3 TRAPPC8 ARHGAP18 FBXO25 METTL7A JMJD1C CYTH1 PAPSS2 CTSH SH3BGRL3 ING1 ITGAL NCF1 PLEKHA2 PIK3CG WDR47 SGPP1 EP300 MEF2D CCPG1 FAM78A	down	***
GSE3982_EOSINOPHIL_VS_TH2_DN	0.0000390	0.0004353	0.5573322	0.3782965	1.700077	176	RIBC2 RUVBL1 CDC45 FAT2 COIL APOLD1 KIF18B PLK1 PTTG1 CCT6A COX11 CCT2 DNPH1 DLG1 SMARCC1 AUNIP PUS7 NDUFS2 TMEM177 P4HTM VANGL1 MPHOSPH9 GPSM2 ACTL6A FBL PERP CAD PHB CNPY2 CMAS NUSAP1 BIRC5 NCAPG CPNE1 NUP205 MRPS12 PA2G4 RANGAP1 DNMT1 FANCG ATP6V0E2 DPH2 IL15RA MRPL4 KIF20B SPA17 AAMP PFAS BAD LSM7 NEK4 TBC1D16 LSM4 MAB21L1 PRMT5 CCNA2 NFRKB SNRPD2 RNF123 NDUFA8 DNAJC10 DHRS3 MRPS27 PWP1 ENO1	up	***
GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP	0.0000282	0.0003335	0.5756103	-0.3199256	-1.697845	176	WEE1 GCOM1 HHEX ZC3H12C HSD17B11 LMO2 MYADM NEDD4L CD22 GGA2 CASP9 PTS UBL3 SLC7A7 RAP1A MAP3K8 LITAF TMEM123 MCL1 TUBB6 TIPARP MPEG1 CASP1 TACR2 YBX3 KLF4 PLAUR PLBD1 CLIC4 SELL EPS15 EVI2A RABGGTB HSDL2 HCK PKIG PHTF2 LIMD1 RAB31 KCTD12 PRKCE HOMER1 KLF2 TCF4 TGIF1 SBF2 PIM1 CCR1 SLC31A1 CD19 FDX1 CTSC MCOLN2 FAM126B RSU1 CTSH SLC38A2 DRAM2 TUBA1A EBF1 ABHD14A UBE3A GPR137B SERP1 MAN1A1 NFIL3 MAP3K1	down	***
GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP	0.0000583	0.0006200	0.5573322	-0.3238002	-1.697570	171	TEK PDLIM2 USHBP1 LIPA BMP2 SH2D3C LDB2 CAV1 MYADM NCF2 FUCA1 PILRA MAN2B1 ASAP1 PTPRM NAAA RASGRP4 CLEC7A PARVG CAV2 ADRB1 DES PPP3CA EPB41L2 EVI2B MTMR6 SCP2 RUNX1T1 PLBD1 COTL1 ITGAX PAPSS1 RECK ARHGAP9 EVI2A HGSNAT PRCP TECR ID4 CYB5R1 PRKACA SUCNR1 UVRAG CYP4A22 ALDH3B1 TIMP2 ZNF521 TGFB1 TEC TSC22D1 PLEKHO2 ESYT1 ARHGAP18 SREBF2 LIMCH1 CD3G RNF38 ITCH ACAT1 CBX7 SVIL CX3CR1 ITGAL FPR1	down	***
GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN	0.0000741	0.0007684	0.5384341	0.3755868	1.696578	185	UCHL1 PRIM2 BRCA1 NDUFS6 IFT27 ACAD9 MCM2 XPNPEP1 XPOT TAMM41 CISD1 KIF23 MKI67 BUB1 TOP2A POLD2 GCAT CHAF1B LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD CNPY2 INCENP CKS1B NUSAP1 CDK1 BIRC5 GMNN ZMIZ2 POLR3K MRPL17 TSPAN31 EZH2 ETFB SNRNP25 DNMT1 MZT2B TUBG1 TACC3 MNS1 MBD4 TRIM37 NUP85 MARCKSL1 RAD50 CENPK CKAP5 CDC20 CKAP2 MCM5 RCC1 HAUS4 MARCKS GADD45G NDUFV1 RFC5 NME4 INO80E HK2 TRAK1 PGAM1 RPN1 CHERP DTD2 NCAPH CYB5B RNF14 UNC119 RCN2 MRTO4	up	***
GSE9988_LPS_VS_LOW_LPS_MONOCYTE_UP	0.0002319	0.0019892	0.5188481	0.3961313	1.695528	120	STYK1 FANCI DEPTOR MPP6 ZNF138 E2F8 PCDHGB6 IGSF11 CDCA8 LAMP5 GLDC LRRC31 PCDHGB8P ZNF485 HHIP-AS1 WDR78 TTC22 SDHAP1 TRMT61B KLHL3 FBXO16 C12orf75 GABRB2 TRAP1 ZNF789 DIAPH3 SEMA4F AMPH DHRS4-AS1 PKP3 ZNF544 GBP6 HMGB3P22 ZNF320 PTHLH STRBP ME1 TMEM72 PARG CGN ZNF204P SLC38A4 TLR5 SLC1A7 MED22 WDR63 PLK4	up	**
GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN	0.0000438	0.0004802	0.5573322	0.3772546	1.694350	175	MDM1 HJURP BRCA1 RACGAP1 E2F8 GTSE1 CENPA TPX2 MCM2 COX6B2 SHMT2 NCAPD2 SPDL1 WDR90 WDR62 EXO1 PAQR4 CCDC77 CENPL EME1 KIF2C MAD1L1 POC1A MPHOSPH9 RAD54L KIF11 FAM162A GET4 CKAP2L DCTPP1 IPO9 INCENP CBX5 HDGF CENPJ RFWD3 NCAPG NUP205 DYNLL2 SAPCD2 CCNE1 TUBG1 UBAC1 TACC3 AARSD1 MBD4 SSRP1 ESCO2 GINS2 ANP32E RAD50 GEMIN6 PRMT1 TDP1 SIRT5 MRPL51 NEFH ATAD2 ECH1 SNRPD2 TPGS2 ZWILCH SUPT3H PAXIP1 VDAC3 DTNBP1 POP4 SEPHS1 DNM1L ILVBL NCAPH TFB1M	up	***
GSE41867_DAY8_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP	0.0003059	0.0025046	0.4984931	0.3980787	1.693585	117	PRR15 MYBPH ABCA17P PHGDH LYPD6B ANKRD24 FBXL19-AS1 DZANK1 ZNF607 GPR37 NLE1 SMAGP TIGD4 FBF1 SLC4A11 CHAF1B RNFT2 ARHGEF34P SCAMP5 LRRC61 BLM PARD3 LAMB4 RNF207 CXCL17 LINC00173 TBX1 CADM4 ITFG2 DLK2 LCN12 RHD CHADL CHRD COL26A1 NSUN6 CEP152 ALMS1 TMC5 ZNF70 ACKR2 ZFP14 PTPRF BCAS3 SH3GL1P2 ZSCAN20 SNAP25 TMEM132B INO80B ANO8 DNAAF1 DNM1P46 SMYD3 AMH THY1 GDF11 CEACAM19	up	**
GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN	0.0000885	0.0008869	0.5384341	-0.3229896	-1.692785	159	SIRPB1 RAB11FIP1 CXCL3 SLC31A2 ACP5 OLR1 ZC3H12C IL1B SNX10 NUP54 TMEM170B HCAR2 RGS9 MS4A15 CDC42EP2 BCL2A1 PILRA HDC SLC7A11 BNIPL TFEC NODAL PTPN12 CCL22 MEFV REST VASP KLF7 CCL4 PLEK N4BP1 FAM102B HCK KANK1 SOCS3 SERPINB8 NXPE3 FOXN2 UBAC2 ACSL1 RHOQ SMPDL3B EHD1 GSAP SOD2 PDE4B ETS2 SLC34A2 SEMA4A CEBPD USPL1 NLRP3 TRAF1 NFKBIA ADORA2A ZDHHC5 SAMSN1	down	***
GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_DN	0.0001719	0.0015654	0.5188481	-0.3264169	-1.692195	148	OSBPL1A TMEM126A GPR65 GLTPD2 EGR2 IBA57 IDI1 PRPF38A BCL2A1 PPM1D IER2 PKHD1L1 RAPGEF4 BTG2 KLF10 ZNF410 PRSS12 ZBTB8A NR4A1 NFE2L2 SPI1 EVI2A MIR17HG RASGEF1B AREG CREM CRNKL1 ETV3 ARL5B HPGDS IFRD1 PNPLA8 GPR183 NUDT15 NAA30 HSF5 TEX30 CNTNAP1 TAGAP LEKR1 GPR18 GEM EXOC2 SLC31A1 TXNDC15 IER5 DCTN4 FBXO30 USH2A DNAJB9 DOCK4 EGR1 CFL2 LRRC63 NR4A2 ICOS YRDC CD69 ANKHD1 TRMT10C NR4A3 YOD1 ZNF331 DUSP2 FBXL13	down	**
GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP	0.0000337	0.0003874	0.5573322	0.3771719	1.691929	173	FOXM1 MDM1 TICRR PARPBP ACY3 BUB1B CENPF CIB2 DEPDC1B TTK GINS1 CDCA2 RACGAP1 ASPM STIL CCNB2 TYMS XDH TMCC1 GINS4 B4GALT4 TP53BP1 AP4M1 BUB1 CCDC77 TOP2A RAD54L KIF11 L3HYPDH HEBP2 MAD2L1 CKAP2L EHHADH XRCC1 SPC24 BLM TTYH3 INCENP CDKN2C CBX5 CTDSP2 CDK1 CENPJ CENPH KRBA1 EZH2 TRAPPC12 ANKRD39 ZNF606 ARHGEF16 URGCP ANP32E CCDC51 PTER SUPT16H CENPM ANKRD6	up	***
GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_UP	0.0000651	0.0006822	0.5384341	0.3768497	1.691240	172	GRIA4 MCM10 BDH1 ELOVL6 ZDHHC4 CHEK2 BUB1B GINS1 CDCA2 IQGAP3 GTSE1 ABCA12 NUF2 ACAD9 MCM8 XPOT EXO1 POLD2 KIF2C WDHD1 FANCD2 MAD2L1 CKAP2L IPO9 BLM SLC18B1 FADS2 IDH2 ALG3 SLC25A10 WWC1 PARP1 CBX5 ASF1B MRPL37 ANAPC5 ARHGAP39 POLE2 PEG10 PDK1 POC1B TRIM24 DLGAP5 SLC35C2 LMNB2 DTYMK SLC4A2 ATAD5 UBQLN4 LIMA1 L3MBTL2 TMEM106B PIGU UTP20 PRODH CUBN RAB34 STRBP PRIM1 RTEL1 VDAC1 CDC42BPA TPGS2 PPP6R2	up	***
GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP	0.0000903	0.0008965	0.5384341	0.3800081	1.691055	161	EIF2B5 GLDC SHMT2 RCCD1 MRPS35 NME1 LDHB NR2C2AP DNPH1 C19orf48 NOP9 PDCD5 EMG1 FAM162A DCTPP1 MRPS30 ALDOA HSPBP1 DHRS13 DDX51 DTD1 ESRP1 ATIC MRPL17 KLHDC9 PSMG3 HMGXB3 TPD52L2 ILF2 SMG5 JOSD2 AARSD1 COL9A2 MRPL11 GINS2 ELAC2 ETV4 KLHDC3 TIMM13 STOML2 CHCHD1 ZNF428 NAT8L SSH3 RABEPK SNAP47 EIF3D ADCK1 TXNL4A VDAC1 ACSF3 HOOK2 TYSND1 ALKBH6 RAD1 CYB5B NDUFAF6 TEAD3 FURIN RPL36 HDAC10 VAC14 NHP2 BATF LOX SPRYD4 PFKL ACOT7 NUDT19 MRPS7 CHCHD5 CDH26 DHX30 PDSS2 TRIM28 C1orf174 SUSD3 CUEDC2 DRG2 RBFA POLR2C MYLK4 PECR TRMT1 SLC7A1 DBH OAS1 PGP SIAH2	up	***
GSE13547_WT_VS_ZFX_KO_BCELL_UP	0.0001822	0.0016376	0.5188481	-0.3247451	-1.690946	147	SLPI ARHGAP31 SOSTDC1 CD101 ACE ENDOU SECISBP2L CD55 CPEB2 ST6GALNAC3 FYN PLEKHA1 YPEL5 NEDD9 DNASE1L3 ZEB2 LRRFIP2 ZBTB4 LATS2 AKT3 IL10 CCL4 LBH CCND2 SNN PIAS1 TBC1D5 CREBRF FRY NSMAF SNX29 JAK1 DAPK2 CD83 PTGER2 CD7 STRN BAZ2B TEC HNRNPH3 RGS2 SYT11 RNF2 RBL2	down	**
GSE8835_HEALTHY_VS_CLL_CD4_TCELL_DN	0.0002298	0.0019774	0.5188481	0.3874251	1.690922	135	RIBC2 HELLS SLC13A3 ELOVL6 DEPTOR B3GAT1 FCER2 CCNB2 LMLN BUB1 CCT5 MMS22L CSRNP3 HOXC6 ARMC12 RAD51AP1 TBC1D8 PTGDR2 BLM HOXB5 FBXO16 MBOAT1 SLC25A10 INCENP C12orf75 GMNN SMG9 GDAP1L1 BBS5 AMPH DNAH7 TSNAXIP1 ADAM28 MAPK13 EPHB2 CNGA4 PRG4 ZSWIM1 DDIT4L GBF1 ZNF76 ARVCF KDM4B TIAM2	up	**
GSE2706_R848_VS_LPS_8H_STIM_DC_DN	0.0000868	0.0008776	0.5384341	-0.3287759	-1.690750	142	RAB11FIP1 FOXF1 CPEB2 SNX10 LY86 PLEKHF2 GNPTAB EPB41L3 LATS2 ABCG1 STOM SLC25A37 TFEC BTG3 LINC00528 GPA33 KLF4 SPAG9 SNIP1 ERP44 C4orf33 PNRC1 PEAK1 N4BP1 RUFY3 HCAR3 CD80 DDX60L SAR1A HRH1 MAP4K4 GYPC OSM STX5 TNFRSF9 PELI1 GJA4 ICAM2 SRSF4 MFSD12 TCF7L1 UNC13D MIR155HG NBN TMOD2 TAB2 STK4 CYTH1 AIM2 NRP2 GRB10 GIMAP4 PMAIP1	down	***
GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN	0.0000478	0.0005179	0.5573322	0.3763143	1.690126	175	KIF20A GALNT14 NUP107 KIF18B SORD TTK UBE2Z ASPM MCM2 CDC25A PRC1 EIF3B CAND1 SHMT2 CCT2 UQCC1 BUB1 CCT5 LARS2 KIF2C MCM7 MPHOSPH9 TMEM45A MRPL3 KIF11 SEC61A1 SDHAP1 TOPBP1 CHEK1 AHCY C7orf26 GEMIN4 THOP1 BIRC5 C1orf112 SUN1 E2F1 TRAP1 RANGAP1 TUBG1 PKP4 AHNAK2 NRF1 POLD1 KDM3A PFAS HMGA1 LRRC59 RPA1 PPP6R1 MCM6 PRMT1 TDP1 DOLPP1 C1QTNF3 PRMT5 COG5 CAPN15 PRDM10 TXNL4B PAK4 TUBGCP4 SMC2 TCF3 NCAPD3 ADCK2 BTN2A1 NUP93 FTSJ3	up	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP	0.0000350	0.0003974	0.5573322	-0.3182413	-1.689115	178	KMO CD52 SASH1 ABHD5 DENND5A TAL1 OSBPL1A PTPRE RAMP2 LY86 LMO2 MYADM AQP9 CYB5R3 GIMAP6 EPB41L3 SH2B3 MAN2B1 BMP1 NAAA MAP3K8 IL18R1 GRN SPRY2 CYP4V2 RAB14 PTPN12 BNIP2 PLAUR ST3GAL2 STK17B KLF7 PLBD1 TMBIM1 ITGAX KLRD1 PRDM5 MAPRE2 HCK CTSS CABLES1 TYROBP APBB2 IRF8 SELENBP1 PRKCE SPOP DDHD2 CRYZL1 TSC22D1 CBFA2T3 GNB4 CD81 MEIS1 RGS2 GEM ICAM1 IL18 PIP4K2A ALDH6A1 S100A4 NFKBIA LTBP3 DNAJB9 THEMIS2	down	***
GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP	0.0001762	0.0015930	0.5188481	-0.3377872	-1.687694	126	OTUD1 BACH1 NEDD4L CRY2 CD9 DENND2C TEX2 PDE2A RASGRP4 ADRB2 RHOB CYBRD1 ARRB1 TCP11L2 ID3 ITIH5 PRF1 DUSP1 TANC1 HEXB SLC25A33 FAM107A SCEL SGK1 JUN VAT1 BTD PPP1R15A GSTO1 TINF2 SNX9 FOS EHD2 FOSB TSC22D1 DUSP5 TGFB1I1 IRS2 NFYC ADPGK RGS2 GIMAP5 DAPK1 PAIP2 ATF4 ACVR1C PRKCH ZFP36 ATP1B1 SORCS2 DNAJB1	down	**
GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP	0.0000330	0.0003801	0.5573322	-0.3178072	-1.686603	176	FCN1 CXCL16 NUP54 GPR65 SIK1 BACH1 ELF2 ARL8B TGFBR2 MOB1B TRIB1 ANXA1 SH2B3 MOAP1 GPA33 PRKD3 FBXL3 DUSP11 ZMPSTE24 RPF1 SLC25A32 IL7R IKZF5 VCPKMT SLC25A33 PPIL4 CCNY DDX20 NOTCH1 MTMR9 FYTTD1 ATXN1L IFRD1 REL SNX9 ASTE1 ADNP2 PTP4A1 FOSB NAP1L5 SMCR8 IRS2 TAGAP CRY1 KANSL2 GEM IER5 IQSEC1 USPL1 CUL3 TTC19 DNAJB9 ZNF165 PUS3 ZNF326 SVIL CRBN ZFP36 TBC1D23 CD69 SPTY2D1 WDR47 DDX21 ITGA6 SECISBP2 HIVEP1	down	***
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_UP	0.0002135	0.0018671	0.5188481	0.3768542	1.686324	166	BBOX1 KIF20A MDM1 TICRR BHMT TIMELESS CIB2 NDC80 AGFG2 RACGAP1 DNMT3B ASPM ECT2 CCNB2 ARHGAP33 PRC1 SMUG1 CDT1 KIF23 CEP55 TOP2A CCT5 AURKA CD2AP MMS22L GPSM2 CDC25C TXNDC5 SPC24 IDH2 DET1 KNSTRN CBX5 CDK1 POLE2 BIRC5 SPAG5 LCA5 VPS72 RAPGEF5 RNASEH2A DNMT1 DLGAP5 SNRPA KIF20B KCNB1 CCDC30 SLFN12 CDR2 ASRGL1 MRPS33 CKAP2 HAUS6	up	**
GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN	0.0000933	0.0009221	0.5384341	0.3751493	1.685289	171	EGLN3 MCM10 FANCI PBK METTL1 GINS1 RACGAP1 TRAIP POLE SPP1 STIL NUF2 CDC6 TPX2 TFDP2 UMPS TDRKH COQ3 NUDT1 CPD DPCD RRM2 CDCA5 RAD54L CHEK1 IFT172 COX19 DCTPP1 DSCC1 MTG1 PSRC1 CKS1B NCAPG2 ASF1B NCAPG PSAT1 CENPP INTS7 UBE3D ASNS CNDP2 CENPK GEMIN6 CPSF4 SLFN12 METTL2B MRPL41 HAX1 ATAD2 ZNF580 TIGD2 STAB1 SHCBP1 PRPF31 LPGAT1 RAD51 OXCT1 UHRF1BP1	up	***
GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN	0.0001135	0.0010939	0.5384341	0.3773540	1.684655	164	TRIP13 SPICE1 PARPBP CCDC34 CENPF PBK C6orf141 CDCA2 ASPM AURKB ECT2 CCNB2 CYP27B1 TYMS DTL RANBP1 MELK MKI67 BUB1 DPY19L1 HAVCR1 E2F2 CENPW SMYD2 GCAT SBK1 GPSM2 CDC25C CHEK1 SPC24 EHF INCENP NCAPG2 NUSAP1 ASF1B UCK2 BIRC5 FAM114A1 DNA2 ITPKA ACTR3B CENPP ZNF606 HDHD3 KIF22 ZNF239 ENPP2 CNDP2 CDC20 EML6 ZRANB3 HAX1 PRSS16 GNAL GADD45G CCNA2 NME4 CPOX SMC2 CENPE EPSTI1 BPNT1 UBE2C KCNK6 TTC5 AVEN COMTD1 NOD1 HINT1 TMPRSS4 KIAA1841 HSD17B7	up	**
GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_DN	0.0000940	0.0009250	0.5384341	-0.3213338	-1.683771	165	CXCL3 ACE RASIP1 TIE1 PTPRE CCRL2 ST3GAL6 INPP5A SFR1 LMNA LIFR ACOT2 RNASE1 NR4A1 RGCC NDEL1 CD93 SPTBN1 SRGN SORBS1 PLAUR ID3 THBS1 LAPTM5 NFKB1 CXCL2 HOPX ACTR3 SS18L2 CMTM6 STK24 FOXN3 ETF1 CD80 AREG IL6 SOCS3 PABPC4 CEBPZ RALB NDST1 HIVEP2 SRSF6 MAPK8 FOSB EHD1 NAB1 STK40 SELPLG GPX3 SLC25A20 CD19 NFKBIA CYTH1 ZFAND2A	down	***
GSE12366_NAIVE_VS_MEMORY_BCELL_UP	0.0001032	0.0010040	0.5384341	-0.3227257	-1.682911	152	LIMS2 PTPRE FIG4 LYL1 MYADM SLC39A8 PLEKHA1 S1PR1 NFATC3 RFTN1 ABCB1 DNASE1L3 SWT1 FOXP1 PCDH12 LAIR1 MAPK8IP1 HIF3A YBX3 TM6SF1 GCA PEAK1 AFF1 IL6 DDHD1 ADAMTSL2 FOXP1-IT1 GAS2L1 ARHGEF10 CD83 PRKCE RC3H1 OGFRL1 XYLT1 HSF5 ADPRM CHPT1 GNB4 APLP2 CRY1 MEGF6 XIRP1 PSME4 FNBP4 CEPT1 EDN1 FDFT1 MMD P2RX1 MROH6 EHD4 FCRL1 ATP6V0A1 DUSP6 KBTBD11 PLEKHA2 FAM53B GNG11 CD79B PDE7B	down	**
GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_DN	0.0002763	0.0022968	0.4984931	0.3827100	1.677325	140	DNAJC22 SLC2A1 ASIC1 LAMP5 DTL NCAPD2 WDR90 FANCA POLA2 MCM7 SMYD2 KIF11 CHAF1B XXYLT1 TOPBP1 C7orf50 SLC25A39 CAD PPIC FAM135A E2F1 UNG KCTD13 GJB3 DHX33 MECR SF3B3 SNRPE ZMAT5 DAP3 SGSM3 RHD PPME1 CHPF RNF187 TSTA3 CENPM ERBB3 TUBG2 DNMT3A MCM5 TMEM147 ALG8 PRIM1 DBNL NDUFA8 MXD3 TBL3 MSRB1 CSTF1 TOMM7 MED22 RPL36 TMPO RASAL1 NPM1 PRCC ARFIP2 CDPF1 SHMT1 GDF11 E2F4 CALM3 PPP4C SAMD14 PFKL	up	**
GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN	0.0000364	0.0004101	0.5573322	-0.3171479	-1.675299	174	SLC24A4 PTPRE EGR2 CD44 WDR74 RASAL2 SRSF7 NCF2 GALNT18 LRRFIP2 HBEGF DNAJC5B LITAF TTYH2 SLC7A11 ZFYVE16 SRGN BTG3 TUBB6 TAPT1 TBC1D9 ADO PLBD1 PAPSS1 ATP6V0D2 ARAP3 PLEK PLCD1 NRROS ARL6IP5 BCAR3 SNAP23 CD48 HK3 CCR7 CD83 LGALS2 OCIAD1 CDK14 CR1 EHD1 PEA15 CD86 KYNU MOB3B RIPK2 TRAF1 PLGRKT TIMP3 ANXA11 C1orf115 PMAIP1 RAP1GAP AFTPH CSF2RB MB21D2 SVIL ITGAL TBC1D23 TUBA1A ATP1B1 NFAM1 PTGS1 ZBTB46 SLC25A45 FCHSD2 CYTL1 NR4A3 MSC PPP1R14A SLC29A3 CYP1B1	down	***
GSE360_CTRL_VS_L_MAJOR_DC_DN	0.0000760	0.0007824	0.5384341	-0.3199616	-1.675270	160	SIRPB1 SLPI FOXF1 GPR15 ADPRH PPARG FCN3 THBD SLC39A8 IL1RN TRIB1 IL23A BMP1 CD5 HSPB1 LITAF KLF6 CAMTA1 SERPINB9 ITSN2 IL10 DENND3 SOCS2 GMPR ID2 DNTTIP2 ARL4A VAMP5 SMNDC1 TDRD7 BTG1 S1PR4 SLC14A1 CCR7 FRYL PTGER2 RAB8A CELF2 RHOQ CDK17 SFTPC DUSP5 IRS2 PIM1 ATP6V0C SOD2 KYNU ETS2 CCR6	down	***
GSE24726_WT_VS_E2_2_KO_PDC_DAY4_POST_DELETION_UP	0.0000683	0.0007114	0.5384341	-0.3159437	-1.673717	175	SLC31A2 KMO SC5D PECAM1 LRRC8C C18orf32 RAPGEF2 CLDND1 AKAP7 CDC42EP2 NR3C1 LAMP1 AGPAT4 SLC11A1 DNAJC3 COQ7 PAG1 CLN5 NFE2L2 SPRY2 TFEC MTHFR FABP5 MAFG RMDN3 PLBD1 IRAK2 C9orf72 HPSE RAP1GDS1 HLA-DQA1 MMP19 LACC1 NINJ1 METAP1 VPS37A DDHD1 JUN USO1 PSTPIP2 HSD17B12 HOMER1 NOP10 CD74 CDC37L1 IFNAR1 DYNC1LI1 STK40 TSPO SEMA4A CEBPD FBXO30 CEPT1 SAMSN1 NRP2 CCND3	down	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN	0.0001141	0.0010939	0.5384341	-0.3193689	-1.673474	165	DNAH17 DLC1 HHEX FABP4 MNDA FBP1 DCSTAMP LPXN GPR65 LIPA GFOD1 RASAL2 LINC00622 NCF2 AVPI1 TXNIP CD36 NCEH1 CLEC7A RGCC KIAA0513 ADO KLF9 MAP1LC3B PAPSS1 TM6SF1 RAP1GDS1 UBASH3B CD300LB MRVI1 PRCP RBPJ PGD OASL MITF CPEB4 TREM1 MALT1 CELF2 FOS TAGAP GABARAPL1 GNA13 MBNL1 IL18 BRWD1 CD1E DOCK10 CAMSAP2 HAT1 DISP1 SERPINE1 C5AR2 GJC1 TBC1D23 PLXDC2 FPR3 HMGN2	down	**
GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP	0.0000302	0.0003511	0.5756103	-0.3147147	-1.673246	180	CD300LF MS4A7 GLIPR2 ZC3H12C RAPGEF2 ST6GALNAC3 KIAA1109 GTF2I RFTN1 TMX4 DNASE1L3 EDEM1 CNST FAM89A PBX3 LITAF REV3L SIRPA RGCC TXN IL10 MPEG1 KLF4 PLAUR COQ10B STK17B TMED5 VRK2 MGAT4A PDE3B DUSP1 PLEK ARL4A RSRC2 LACC1 CD80 CHDH BCAR3 HIC1 MN1 HSPA1B JUNB DUSP8 FSD2 TPP2 DOCK8 TBX21 SLC3A2 PNPLA2 UBXN2A EHD1 GSAP TEX30 SBF2 CTNNAL1 CD86 IFNLR1 RNF138 HSPA2 HSPA8 FDX1 GPR171 SAMSN1 C21orf91 NRP2 EHD3 BMI1	down	***
GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP	0.0001603	0.0014848	0.5188481	-0.3196738	-1.672275	158	RAB11FIP1 HHEX RCOR1 FOLR1 RTN3 MTMR10 YPEL5 AGTPBP1 TGFBR2 FAM49A TMX4 CHMP1B NDEL1 SLC25A37 TLE4 AOC3 ST3GAL2 OSTF1 COTL1 PTPRC ARAP3 PPP2R5C GNAI2 NRBF2 PRCP RYBP NEK7 GLIPR1 DOCK8 TAGLN2 CELF2 TIMP2 ZRANB1 BAZ2B IRS2 MAP3K2 HBP1 APLP2 ACTN2 PHF2 BNIP3L XKR8 TOB2 TBC1D1 METTL7A KIT ARPC5 PTEN FAM126B CYTH1 PAIP2 IQGAP1 SPOPL HIPK1 CX3CR1 MAPK1 RAB37 NFAM1 FAR1 FAM160B1 STX16 MAP3K1 TRIM25 WDFY2	down	**
GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN	0.0002782	0.0023091	0.4984931	0.3728083	1.672045	168	FOXM1 KCNK5 BDH1 NUP107 CCNB1 POLQ PAGR1 ANKZF1 TRAIP TRIB3 UHRF1 EXOC3 RCCD1 ASTN2 KCNN4 EMC9 PAFAH1B3 FANCA EME1 NDUFS2 LETMD1 SARS2 EHHADH BRIP1 GNPDA1 GLE1 MEOX1 NUDT2 UNG ZNF775 MECR COA4 ETFB DIAPH3 QPRT RNASEH2A PSMA5 LMNB2 RAD51D FBXO4 FUCA2 GEMIN6 TADA3 DHRS1 LINC00467 HMGA1 RABEPK CACNB3 FBXO36 MRPL51 CCNG1 HAUS4 GLO1 PFKM ZSCAN22 GBP2 ETHE1 SNUPN KDM5B NCAPD3 ENO1 PRKAG1 NCAPH CYB5B HEXIM2 TRAFD1 MRPL12 CBLN3 MSH6 DHX32 STXBP1 CDPF1 SHMT1 KEAP1 TXN2 POLD3 METTL9 STMN1 COA6 RMI2 SKA3 SLC29A1 MRPL35 AJUBA	up	**
GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP	0.0001158	0.0011045	0.5384341	-0.3206705	-1.671620	155	CXCL3 PPARG ZC3H12C FABP4 LPL EGR2 SAMHD1 ZCCHC2 ELF2 ALAS1 CD9 IL1RN CD36 LMNA ENTPD1 CLEC7A CYB5A TNIP3 RNF144B ANXA5 ANPEP TTYH2 TFRC AHNAK MED11 CLIC4 ATF3 HPSE ATP6V0D2 GPR157 SPRYD7 CD300LB VWF VAT1 CPEB4 CCDC50 CD83 FOS CD74 LGALS3 GABARAPL1 BRI3 MFSD12	down	**
KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN	0.0000428	0.0004710	0.5573322	-0.3133039	-1.670779	182	LPIN2 DENND5A SNX10 CLDND1 KCTD9 TTC7B CD44 ST3GAL6 MYADM AQP9 BCL2A1 FGR ANXA1 ENTPD1 RAB33B LITAF KLF10 SERPINB9 IL18R1 CRTAM SRGN TXN AHNAK SORBS1 CASP1 YBX3 SOCS2 CTSD LAPTM5 ITGAX HOPX ID2 CCL4 RECK PRF1 KLRD1 MBD2 DSTN MAPRE2 EMP3 CD160 GABARAPL2 SLC35E4 EEA1 DAPK2 GMFG RHOQ KRTCAP2 CHPT1 LGALS3 FCGRT IL18RAP ACTB S100A4 ADORA2A KLRK1 RORA CCND3 RSU1 NR4A2 ITGAL ITGB1 ALG2 POLR2L RPA2 ATF6 DOCK5 FAM89B CD4 CASP3 GZMB RNF19B MYO1F KLRC1 EMP1 KLRG1 TERF1 GZMK IL10RA	down	***
GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN	0.0000416	0.0004592	0.5573322	-0.3173931	-1.670695	170	CXCL3 EREG KMO DENND5A ROBO4 RAPGEF2 BMP2 SLC39A8 CDC42EP2 OTUD4 LRRFIP2 ADA EIF1 BZW1 LITAF SLC7A11 RBM4 ARHGEF2 CASP5 MAP2K3 STAT5A SNAI1 PTGIR TJP1 SOCS2 SNIP1 CXCL2 TP53BP2 MARK3 AKIRIN1 NINJ1 CD80 SAR1A PSEN1 RAB8B PPP1R15A PTGER4 GRB2 REL PELI1 HIVEP2 PRKCG RIN2 EHD1 ITGA9 FPR2 PHF11 MFSD12 PDE4B GTF2B ARAP2 ABL2 NBN DCTN4 LRP12	down	***
GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP	0.0000864	0.0008756	0.5384341	-0.3186321	-1.670475	171	CXCL3 EREG EDNRB TBX3 RBMS2 CPEB2 FIG4 PPP4R1 CCRL2 MTMR10 TRIB1 SEMA6D PKHD1L1 LITAF PTX3 TOR1AIP1 CD93 TUBB6 IL10 FOXO1 DGKE NPNT KLF4 PLAUR DAB2 ZFAND5 CXCL2 CCL4 N4BP1 HLA-DQA1 TULP2 SOCS3 OASL ETV3 SLC14A1 KCTD12 ARHGEF10 RHOJ RCAN1 PRKCE REL CLN3 FOS EPPK1 RIN2 PIK3AP1 SAV1 PDLIM1 BMP2K GEM FGF2 B3GALNT1 TIAM1 TDRP TBC1D1 ING2 EDN1 EPB41L4A CYTH1 THEMIS2 MT2A ZBTB44 RABGEF1	down	***
GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN	0.0002047	0.0018068	0.5188481	-0.3207765	-1.670039	156	SLC6A4 SOWAHC TUBB1 IL1RN TOE1 RBM7 ANXA1 MAN2B1 LATS2 CHMP1B EIF4E JAM3 CD93 HNRNPU MCL1 EIF1B CDADC1 ID3 THBS1 ADAMTS9 CXCL2 ATF3 ELAC1 SELP HOPX UBE2B CLEC9A VWF PROCR SLC25A25 PDE5A GPR141 FERMT2 SKIL MBNL2 HOMER1 CXCL5 RNF24 KLRC2 CCR4 SMCR8 TOB1 ARPP19 RTN4 NLRP3 KLRK1 PAIP2 EIF4G2 CBX7 JDP2 GNG11 PTDSS1 SPTY2D1 ABHD14A AKAP12 DR1 NR4A3 CFLAR NFKBIZ SKP1 KLRC1 FBXO33 RFC1 TNFAIP6 PLCL1 TRPC6 ADAMTS1 EEF1A1 WDR75 SNX20 RBPMS2 WDFY1 ALOX12	down	**
GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP	0.0000903	0.0008965	0.5384341	-0.3179444	-1.669762	164	GPR65 MIR22HG SIK1 LDB2 CITED2 YPEL5 TXNIP ANXA1 DPEP2 BTG2 CLK1 TCF7L2 ITPRIP PSTK KLF4 COQ10B LEPROTL1 DUSP1 IL7R MYH11 PIK3R5 MAFF MYLIP WASF2 KLRB1 SGK1 HCST MAP4K4 TYROBP JUNB SKIL FOS KLF2 YPEL2 ZNF669 BIN2 ADPRM VAV3 TGIF1 FAM228B ZNF844 IRS2 KCNA3 TOB1 RGS2 PDE4B EPHA4 OSER1 RORA ITCH ZFAND2A TNFRSF10D ARRDC2 CDC14A TNFSF8 MDS2 NR4A2 CLEC4E GPR153 FAM8A1 SLC26A11 ASH1L-AS1 MICAL1	down	***
GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP	0.0000787	0.0008041	0.5384341	-0.3198513	-1.668901	168	SC5D KLF13 SIK1 FYN HSD17B11 ELF2 PLEKHA1 S1PR1 TGFBR2 IER2 KIAA0355 DPEP2 BTG2 RNF125 LITAF CLK1 PPP3CC ARRB1 FOXO1 SRSF5 BNIP2 GPA33 ITM2B PSPN COQ10B LEPROTL1 ARNTL MGAT4A SMAD7 BRF2 PIAS1 ID4 CD48 DNASE2 WTAP PTGER4 PIK3R1 GYPC HIVEP2 CD6 CDC37L1 TSPAN14 TOB1 ACYP2 KANSL2 KAT2B PDE4B EPN2 CXCR4 OSER1 ICAM3 JMJD1C CYTH1 DAZAP2 IL16 ZBTB40 SMPD1 ARHGEF18 ACSM5	down	***
GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP	0.0000577	0.0006162	0.5573322	-0.3147225	-1.668875	181	HCAR2 CCRL2 SLC39A8 STX11 VAPA TET2 IER2 PPP1R15B HDC KLF6 TFEC CSRNP1 STAT5A PLAUR SLC12A4 ZFAND5 CLIC4 TMBIM1 MGAT4A P2RY2 MYH11 SPRYD7 KPNA3 AFF1 RSRC2 KREMEN1 SNN FLT1 RYBP APPL1 ETV3 LRCH1 RCAN1 DHX15 ACKR3 CD83 HSPA13 LGI4 RBM22 REL HNRNPA2B1 PIM1 GNA13 MICU3 PDE4B FAM98B GTF2B MOB3B INO80 ADAMTS4 RIPK2 IPO5 RND1 EDN1 TTC19 SFPQ TRIM36 SPATA13 SPHK1 YTHDC1 JDP2 RBMXL1 DCUN1D3 ZFP36 WAC FANCC DR1 NFIL3 PPFIBP1 FCHSD2 JARID2	down	***
GSE7509_DC_VS_MONOCYTE_DN	0.0000864	0.0008756	0.5384341	-0.3182613	-1.668531	171	CXCL3 SLPI ACP5 OLR1 SNX10 CCRL2 AQP9 PRPF38A MARCO MOB1B FGR IER2 RHOA ADA SLC7A7 RAB33B CYB5A ABCG1 SLC7A11 MS4A1 RGCC SPI1 TXN RHOB PTGIR KLF4 KLF7 CLIC4 MARVELD1 CD302 INHBA CPT1A HLA-DQA1 TANC1 HCK PROCR PSEN1 GMFG FSTL3 ACSL1 KRTCAP2 KLF2 ECI2 SRSF6 FPR2 NAB1 SOD2 MAGOH PLAA TSPO ETS2 CCR6 TRAF1 NFKBIA EPB41L4A C1orf52 GIMAP4 ATF4 SMPD1 RAP1GAP FKBP1B CLEC4E S100A8 FPR1	down	***
GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP	0.0001800	0.0016231	0.5188481	0.3715946	1.667785	174	MEGF10 TROAP BUB1B ANKFN1 CENPF PBK KIF18B RACGAP1 IQGAP3 DGCR8 PLK1 NUF2 NNT CCNB2 CCNF XPO5 MIS18A FSTL4 SLC4A8 TAMM41 MKI67 PCCB COPG1 KIF2C MCM7 KIF11 FANCD2 TRMT2A CAD IPO9 BLM IDH2 WWC1 PARP1 CMAS ANAPC5 PEG10 POC1B NOP2 DNMT1 INTS7 DLGAP5 C19orf44 ADAM12 SND1 NRF1 NADSYN1 L3MBTL2 KDELR3 TMEM106B BEND6 NOL6 WDR35 CLUH PRODH RAB34 CDC42BPA SHCBP1 NAV1 RAD51 R3HDM4	up	**
GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP	0.0000881	0.0008846	0.5384341	-0.3179633	-1.666969	171	SC5D ADCY9 CTSW ST3GAL6 MAL LAMP1 TGFBR2 TXNIP HBEGF ADA BTG2 HNRNPDL SORBS3 TIPARP CCNI SDCBP BNIP2 LEPROTL1 STX3 SPAG9 UBE2B PER1 RNF139 IL7R PLCD1 FOXN3 BTG1 RBM39 AREG CREM SGK1 JUNB PPP1R15A CCR7 SNRK SRSF6 GABARAPL1 FCGRT CLEC2B PDE4B JUND RBL2 TPT1 RPS13 CYTH1 FGFR1 DAZAP2 MT2A EIF4A2	down	***
GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP	0.0000787	0.0008041	0.5384341	-0.3142869	-1.664940	175	CD300LF ADTRP OSBPL1A HHEX GATA2 SPN TTC7B BAIAP2 CRY2 GPCPD1 SLC25A30 CD9 IL1RN MOB1B CD5 HIPK3 SIRPA HNRNPDL TFEC TMEM38B CCNI ROCK2 DGKE CASP1 BST1 USP2 GRK5 SOCS5 COTL1 PIK3C2A CPT1A CMTM6 MCMBP TECR RAB8B DDX47 DESI2 JAK1 IPO7 EEA1 NAA30 CD1D VAMP4 CSDE1 GNA13 ADAM10 PLA2G15 ATAD2B RBL2 CPQ INO80 RTN4 FNBP4 CTSC B3GNT2 IQGAP1 DUT MACROD2 BMI1 UBAP1 NAF1 PRKCH ITGB1 FTL	down	***
GSE22886_NAIVE_VS_MEMORY_TCELL_DN	0.0000342	0.0003920	0.5573322	-0.3131272	-1.664805	180	ACP5 IL17RB GPR15 CD44 TMOD3 CITED2 SLC39A8 EDEM1 RAP1A TMEM123 FLI1 EVI2B LIMS1 ITM2B FUT7 DOCK9 UXS1 CCND2 ELK3 DSTN TP53BP2 DEGS1 SEC31A LMBRD1 PHTF2 PPP6C AQP3 HECA PSMA1 FOXN2 WTAP TSPYL1 YWHAZ TAGLN2 CALM1 HIVEP2 ICAM2 CR1 CCR4 TEX14 TPMT NFYC ORC2 N4BP2L2 CCR6 SESN1 ACAP2 EPHA4 TAB2 CCR9 MEX3C DUSP7 SNX15 SAMSN1 LPAR6 EHD4 EID1 DNAJA2 EIF4G2 CRTAP CMPK1 YWHAB KCMF1 MATR3 RAD21 RCBTB2 TRAT1 BMPR1A CBFB IVNS1ABP CBLL1 MFHAS1 ISCA1 KDM4C CAPG SLAMF1 AIDA CD47 CREBL2 PDS5A	down	***
GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP	0.0000455	0.0004943	0.5573322	-0.3161701	-1.664257	170	RAB11FIP1 SLC31A2 ARHGAP31 EDNRB PECAM1 SPN LRRC8C DCSTAMP RAPGEF2 PID1 SIK1 HCAR2 MYD88 CDC42EP2 IL1RN SCARF1 HEG1 ITGA5 FBXL5 MEFV DRAM1 VASP KLF7 MYO1B NFKB1 GPR85 CD302 N4BP1 PIK3R5 HCK LACC1 SH3BP5 KCTD12 ETS1 NXPE3 GMFG MALT1 LPCAT2 TNFRSF10B RRAS GSAP JMJD6 KCNA3 SOD2 GPR18 PDE4B	down	***
GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_UP	0.0000486	0.0005223	0.5573322	-0.3155431	-1.660957	170	ARHGAP31 OLR1 FABP4 CALCRL MEF2A NEDD9 DSCAML1 SLC25A17 EIF1 FOXP1 SLC7A11 SERPINB9 FOXJ3 FAM122A SLC25A37 IL10 SLC12A4 KLF9 STK17B CLDN5 CDKN1A P2RY2 GPR85 DUSP1 WDR48 SPRYD7 KREMEN1 GPBP1 JUN HPGDS STAT4 EPC1 IFRD1 IRF8 GYPC REL ACSL1 FOS GIMAP1 AZIN1 GLRA3 TGIF1 KCTD10 FEM1B CD86 IRS2 AOX1 TPMT KCNA3 ZNF296 ETS2 ICAM1 PDLIM5 SLC25A20 PTCH1 TRAF1 PKNOX2 LTBP3 MMD MT2A HTRA2 BHLHE41 CHIC2	down	***
GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP	0.0001639	0.0015149	0.5188481	-0.3153872	-1.659917	169	AKAP5 MS4A7 LRRFIP1 TGFBR3 ZEB2 DNAJB14 ATP2B1 SIRPB2 LATS2 EIF1 C1orf21 ABCG2 ADRB2 IL18R1 ERP44 LAPTM5 P2RY2 CCL4 SNORA28 PRF1 FCER1G DSE SH2D2A ACTR2 CREBRF C20orf194 SHOC2 WTAP PTGER4 PSTPIP2 ZNF683 RUNX3 NKG7 SERPINB1 FAM228B DUSP5 SYT11 NEK1 ITPRIPL2 HAVCR2 S100A4 BCAT1 PDE4A PAK2 CREG1 PAPSS2 EGR1 DUSP6 SH3BGRL3 NR4A2 CLOCK KMT2E ATP1B1 C6orf62 FBXW12 ZBED6 TSC22D2 S1PR5 ATP2B4 KATNAL1 METRNL GZMB CYP1B1 GPATCH2L ZNF80 RANBP2 IL10RA ANKRD17 AP5B1 TRA2A DUSP10 BCAP29 HIP1 SESN2 WAC-AS1 SNTB2 RAP2A TLR3 PHF20 SMURF2	down	**
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP	0.0001042	0.0010117	0.5384341	-0.3159784	-1.659437	164	SC5D DENND5A SIK1 HSD17B11 SAMHD1 LDB2 YPEL5 AGTPBP1 PTPRM PDE4D ARRB1 ITPRIP AHNAK PSTK DENND6A KLF4 ST7L DUSP1 RNF139 UBASH3B PIK3R5 MAFF C16orf54 SNN TBC1D5 AREG SOCS3 AQP3 JUN MAP4K4 JUNB ATXN1L SKIL OGFRL1 TAGLN2 FOS PTP4A1 ZNF669 TRAPPC10 BIN2 NAP1L5 FAM204A ADPRM GSAP TSC22D1 ZNF844 IRS2 KCNA3 DOK2 TOB1 RGS2 KAT2B HAUS3 CCDC69 CGRRF1 ARRB2 EPHA4 ZBTB25 TTC32 ITCH ZFAND2A PIEZO1 CFL2 MDS2	down	**
GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	0.0000988	0.0009646	0.5384341	-0.3179257	-1.658854	168	ATXN3 INPP5K S1PR1 IL23A SDE2 BTG2 MED19 PAG1 CRK CSRNP1 MTMR6 PSTK DENND6A COQ10B LEPROTL1 TADA2B UBE2B WDR48 SLC25A32 IL7R UBASH3B MYLIP CCNY CREM DCTN6 PLK3 IFNGR1 MTMR9 FYTTD1 CCR7 CD83 ENTPD4 CEBPZ ZNF350 PELI1 SRSF6 ADPRM SMCR8 SH3RF3 CDC37L1 TSPAN14 MAP3K2 RELL1 KTI12 GEM INO80 NBN USPL1 UBE2D1 NUP98 RNF38 EPB41L4A MTUS1 ZNF791 PUS3 RBMXL1 CDC14A TNFSF8 RB1CC1 YRDC CSNK1G3 CD69 NOL9 SLU7 RAB11FIP2 NR4A3 HIVEP1	down	***
GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN	0.0000933	0.0009221	0.5384341	0.3690360	1.658461	176	TRIP13 FOXM1 KIF20A FAM81A MCM10 FBXW8 MND1 PBK BRCA1 TTK GINS1 CDK4 GTSE1 CENPA ECT2 CDC6 UHRF1 SMPDL3A CCNF DTL LIME1 COQ3 MANSC1 MELK PCDHGC4 KIF2C CPD MORN1 TRPT1 BRI3BP AHCY DSCC1 PERP PML FLNB SPRY1 NUSAP1 STON2 CENPH DNA2 TTC16 ABHD4 IFT52 ALDH7A1 NMRAL1 MNS1 C9orf152 ESCO2 GINS2 HIP1R CENPK DHRS1 CKAP5	up	***
GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN	0.0002184	0.0019004	0.5188481	0.3693652	1.657779	174	TRIP13 EGLN3 AK4 KNOP1 CA12 EIF3B ACY1 CASP2 MRPL15 EXOC4 SAE1 ASCC2 COASY TTLL12 GCAT PKM XXYLT1 DCTPP1 SLC39A11 SSBP1 L2HGDH DGAT2 NUP205 DDT DPP3 CDC23 GNPAT GPR68 MLF2 SPTSSA DUSP12 DNAJC11 NDUFA13 TRIM32 ASNS SAP30 C15orf41 TSEN54 SND1 SIL1 C12orf73 MAGOHB CENPV IARS2 ZNF428 METTL2B UTP20 TDP1 POLR2I GRHL1 HLCS GRAMD1B SUPT3H ACP1 CPOX UQCRQ XPC PFDN4 NDOR1 TRUB1 SIGMAR1 TAF4 FBXO45 NDUFAF6 ZNF511 ISYNA1 C7orf25 RPP25 HRAS PPARGC1B ZNF771 NHP2 CCDC6 GCSH NETO2 LRP8	up	**
GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN	0.0000398	0.0004417	0.5573322	-0.3116449	-1.656925	180	IL1B RAPGEF2 LRRFIP1 RBM14 BCL2A1 VAPA HPS5 ATP2B1 TRA2B LTBP4 ADAM17 RANBP9 PAQR3 SPRY2 CD58 EVI2B MAP2K3 ADO NFKB1 ATF3 CDS2 HOPX CCL4 MATK SH2D2A PPP2CA NSMAF PNO1 SERPINB8 CYCS RHOG TMEM251 IPO7 IFRD1 EEA1 SP3 IDS ZBTB24 REL DLEU2 ACSL1 HIVEP2 FEM1B DUSP5 NAB1 GNG5 ZNF267 PGGT1B MBNL1 GEM IL18RAP WDR1 CDC42EP3 NLRP3 UBE2D1 TRAF1 PSMD9 NUP160 FEZ2 NUP88 TUBA1A WDR47 BCL10 TSC22D2 GABPB1 KLHL9 SRR IRF4 DUSP2 CYP1B1 IVNS1ABP PNP RANBP2 TNFRSF1B GNL2 SUCLA2 EIF4A3 PSMD14 EZR AGO2 FASLG PTPN22 SACS SEC62 PRNP	down	***
GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP	0.0000961	0.0009425	0.5384341	0.3686578	1.655739	175	SPATA24 CPLX2 CDC45 BUB1B TSFM DEPDC1 IRS1 TUBB2B TTK E2F8 CDCA8 IGLC7 ESPL1 KIAA0895 MELK EME1 KLHL25 KIF2C CENPW GPSM2 PPP1R35 ZNHIT1 CKAP2L CBY1 COX19 SPC24 GLE1 KNSTRN FAM221A TRIM2 NEIL3 SPAG5 STK11 LGR5 DLGAP5 TACC3 EFCAB2 AARSD1 ZMAT5 DUSP12 ARF5 ESCO2 PPME1 NAT9 CKAP5 CDC20 CENPM ZCCHC17 KLHL32 ZNF428 ASCC1 TDP1 DNAJC21 ENOX1 SMARCA4 ABCF2 WDR4 CARHSP1 F13A1 WLS RBM19 PNKP TRIB2 UBE2C MSRB1 ZFPM1 NCAPH CD38	up	***
GSE3982_BASOPHIL_VS_TH1_UP	0.0001264	0.0011890	0.5188481	-0.3153593	-1.655685	167	SWAP70 LYL1 PLEKHF2 RTN3 NTM P2RY13 CD9 AGTPBP1 FRAT1 FGR RHOA SH2B3 EMILIN2 SERINC1 PBX3 CLK1 FBXL5 SCP2 SDCBP SORBS1 KLF9 MAP1LC3B PLBD1 PTPRC TLR4 DUSP1 RNF139 DSE PPP2R5A BCLAF1 LMBRD1 ARHGDIB HCK USP25 ZCWPW1 WSCD2 GRIA1 CD164 MBP ICAM2 SRSF6 BIN2 CR1 BTBD7 BAZ2B TSC22D1 GALC HBP1 EXOC1 N4BP2L2 SERINC3 PRDM8 IQSEC1 MEGF9 S100A4 MARC1 KIT FAM13B EIF4A2	down	**
GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_UP	0.0000897	0.0008946	0.5384341	-0.3116934	-1.655648	177	OLR1 OSBPL11 CAT LRRFIP1 LY86 RTN3 CITED2 QKI CTDSP1 MKNK1 CD9 PILRA TXNIP DPEP2 TACC1 PBX3 ABHD6 PPP3CA CD37 EPB41L2 ZMIZ1 BST1 RNFT1 PRKD3 SLC7A8 KLF7 ITPK1 CARS2 HTT FKBP15 LMBRD1 SIAH1 HGSNAT NCKAP1L TBC1D5 RPS6KA2 ARHGAP17 CDC40 IFNGR1 PIK3R1 APH1B CACYBP CD74 KIAA0232 VAMP4 ADAM10 HELZ SELPLG RPP30 FKBP1A MS4A4A MTO1 ITGAE ALDH6A1 SLC2A9 BRWD1 IFFO1	down	***
GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN	0.0002747	0.0022914	0.4984931	0.3704247	1.655617	165	DDIT4 SORD STIL SPINT2 CCNF SHMT2 GSDMB MAGEF1 PAQR4 STAP2 COPG2 AURKA NDUFS2 MPHOSPH9 SLC9A3R1 CBX5 ASF1B CD300A DTD1 POLR3K KIF2A FEN1 CBX1 RECQL4 FOCAD CHCHD3 SNRNP25 DNMT1 RHOC GNPAT GALK2 GSS SLC37A4 MTA3 PRMT7 GFM2 COPS6 NADSYN1 P4HA1 ANKRD6 FBXO22 SIRT5 TMUB1 CCNA2 SNRPD2 ARHGAP11A MICU1 WDR76 TMEM101 ETHE1 VDAC3 PAICS PCBD1 SPATA20 DDB2 C4orf46 LINC00888 PRKAG1 CLNS1A TFB1M CD38 APEH EIF2D ZDHHC13 CLPP SRI MCEE MPST RNF144A	up	**
GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN	0.0000609	0.0006422	0.5573322	-0.3138958	-1.655066	173	SASH1 EDNRB USP12 SOWAHC LTA4H SOX17 DDX6 SRSF7 GIMAP6 VAPA NFATC3 LACTB CORO6 CHMP1B AHRR MAP3K8 COX18 TMEM123 CRK MCL1 ZYG11B FLI1 ZADH2 FAM49B ID2 KLRD1 KBTBD4 TM9SF2 MYH11 MARK3 HCK MTPN ELF1 LRRTM2 EBAG9 HMBOX1 ETS1 ELOVL7 FERMT2 DDX5 NAA30 TSPYL1 RHOQ CD164 HIVEP2 STXBP3 NIPA2 AOX1 GLRA1 ABI3BP RTN4 ALDH6A1 DAPK1 STAM2 FAM126B KIF1B FCRL1 PAPSS2	down	***
GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP	0.0000940	0.0009250	0.5384341	-0.3123497	-1.654678	175	ARHGAP31 GAPT PLEKHF2 QKI CDC42EP2 EPB41L3 TGFBR2 FAM49A IL23A ADA RAP1A MTF1 MAP3K8 RNF144B LAIR1 NFE2L2 EPM2AIP1 ARRB1 BIRC2 PPM1K PTAFR VASP STK17B THBS1 KLF7 CLIC4 TLR4 PNRC1 CCSER2 PIK3R5 HCK LACC1 HCAR3 SYNPO2 SOCS3 OASL DNAJA1 FOXN2 GRB2 RBM22 TNFRSF9 TNFRSF10B NDUFV2 ACSL1 MYL12A RIN2 PIK3AP1 EHD1 FPR2	down	***
GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP	0.0000481	0.0005186	0.5573322	-0.3108217	-1.653295	187	SC5D SNX10 PTP4A2 RCOR1 GTF2E2 PLEKHA1 BCL2A1 CD9 RRAGC UBL3 ASAH1 SRGN UBE2D3 EPB41L2 ARRB1 AHNAK LIN7C RNFT1 ITM2B PRKD3 ROCK1 OSTF1 SNIP1 ITIH5 RECK ARAP3 PLEKHB2 EPS15 KLRD1 PPP2R5C TM9SF2 IL7R SMNDC1 DEGS1 RNF149 KCTD12 IFNGR1 EEA1 SMU1 RAB8A SNX9 RHOQ PELI1 YTHDF3 VAMP4 RGS2 ADAM10 SERINC3 PPID HAUS3 VPS4B HNRNPK OSER1 B3GNT2 DNAJB9 DAZAP2 NABP1 EID1 RSU1 RAB2A PPP1CB PHYH TMEM30A HMGCS1 PRKCH	down	***
GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP	0.0002115	0.0018596	0.5188481	-0.3153536	-1.653256	163	MYO7B OLR1 DENND5A FCER1A ADRA1D SLC39A8 VAMP2 MAL CD1C ABCB1 DNASE1L3 TOE1 TRA2B LMNA EIF1 ITGA5 ADIPOR1 CLK1 MOAP1 MVB12B LRRC40 ELK3 DSE MATN2 GNAQ MAFF TOPORS BTG1 AREG ASNSD1 KIF13A UBQLN3 SRSF3 ETV3 GAS2L1 PTGER4 CCR7 IFRD1 N4BP3 NIPSNAP3B IP6K1 RUNX3 SRSF6 PKIA TGFB1 VAV3 JMJD6 CD6 TGFB1I1 ZNF136 GABARAPL1 TOB1 CCNH SESN1 RTN1	down	**
GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_DN	0.0004180	0.0032896	0.4984931	0.3693881	1.652915	166	SPATA24 CPLX2 CENPF APOLD1 CLGN BRCA1 GINS1 SLC27A2 COLQ DGCR8 UHRF1 UMPS MYBL2 LSM5 KIF23 CEP55 AUNIP EME1 CDCA5 SBK1 FANCD2 ANG SMYD5 CKAP2L SPC24 INCENP THOP1 C1orf112 POLR3K TRIM2 TTC16 CBX1 RECQL4 CENPP RAPGEF5 NMNAT2 MYO19 LGR5 GOLGA3 DLGAP5 ATP6V0E2 TACC3 CENPQ GAS2 SAP30 CHADL CEP128 ZNF428 SNRPD1 HAUS6 MYEF2 STRBP ADM PRR11 WDR4 BRMS1 RNF7 POP4 NMT1 TBL3 E2F7 DDX41 SLC1A7 DLEU7 LONRF2	up	**
GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP	0.0000581	0.0006192	0.5573322	-0.3127831	-1.652243	174	CD52 CD101 OSBPL1A HHEX FABP4 CLEC3B CAT LY86 RASAL2 MEF2A VAPA CD9 AVPI1 TXNIP DPEP2 ATP2B1 ECHDC1 REV3L TNS1 GRN APOC1 ZYG11B SORBS3 FABP5 CFD PPT1 CPVL SLC7A8 ZADH2 CEBPA CADM1 CD302 TAF9 BACE1 CDKN2AIP CNRIP1 RPS6KA2 PRCP TECR CCNY SNX29 PABPC4 WDR7 GAS2L3 GRSF1 TIMP2 CD86 LGALS3 CLEC2B PLA2G15 GPX3 HAVCR2 AMZ2P1 ACADM CD1E FAM13B STARD13 CRTAP TREML1 C5 TREM2 ATP1B1 CBR4	down	***
GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_DN	0.0000977	0.0009556	0.5384341	-0.3110468	-1.652214	177	OTUD1 KLHL8 BACH1 CRY2 INPP5A NR3C1 ZBTB2 FAM49A DENND2C NUMB LATS2 CHMP1B TMEM204 TTYH2 KLF6 SETD3 RHOB ARRB1 CCDC82 LEPROTL1 CDIP1 RRM2B KLF7 MARVELD1 CDS2 ELAC1 SMAD7 DEGS1 RPS6KA2 SERTAD2 RYBP PDCD6IP ETV3 ETS1 CELF1 SHOC2 BAG5 RASSF2 LETM2 RNF146 PNPLA2 PHF3 CD1D KCTD10 TEC PIK3C3 TAGAP NBEAL1 RGS2 INO80 IER5 DAPK1 RBM48 RASSF8 TTC28 DNAJB9 RSU1 SMAD4 MAN1C1 SPPL2A TMEM43 LNPEP PATL2 RNF167	down	***
GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN	0.0000589	0.0006249	0.5573322	-0.3124882	-1.650685	174	SIRPB1 SMAD6 LIMS2 ACP5 IL1A HMOX1 MCOLN1 OSBPL11 PECAM1 FABP4 SNX10 THBD NEDD4L GPCPD1 TGFBR3 IL1RN AVPI1 ECHDC1 PICALM ABCG1 KLF10 ATP6V1B2 TBC1D9 UHRF1BP1L KLF11 PDE3B NR1D2 IRAK2 AXL ATP6V0D2 PLEKHB2 CPT1A PRICKLE2 USP16 HSDL2 ELF1 UTRN MED30 PTGER2 ATP13A3 SNX9 ECI2 SORT1 NIPA2 VAV3 NR2C1	down	***
GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_UP	0.0001957	0.0017339	0.5188481	-0.3149494	-1.650646	159	SLC31A2 EREG PID1 FYN MS4A15 MARCO BCL2A1 SLC11A1 MCTP1 SIRPB2 ASAH1 AHRR NFE2L2 BTG3 TCF7L2 TMEM38B FBXL5 LIMS1 BST1 PLAUR DAB2 STX3 ARAP3 ALOX5AP EVI2A PINK1 FKBP15 IL24 KREMEN1 PROCR HCAR3 DDX60L VPS37A NSMAF PDCD6IP ARL5B SH3BP5 CCDC50 TMEM251 GSTO1 PNPLA8 NDST1 TINF2 SNX9 RUNX3 MYL12A ZFAND6 VAV3 TSC22D1 IRS2 BRI3 LTBP1 CCL20 BNIP3L ATP9B ING2 BCAT1 RET B3GNT2 MROH6 IL16	down	**
GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN	0.0000997	0.0009717	0.5384341	-0.3130852	-1.650329	172	SLC6A4 TAL1 PTPRE HCAR2 CAV1 NUDT9 DYRK1A NR3C1 IL1RN PPP1R15B ABCG2 RAB33B MAP3K8 ZNF410 MCL1 TMEM38B FUT7 VRK2 CDKN1A ATF3 GCA ZDHHC20 NINJ1 ARHGAP17 MCMBP SYNPO2 ESD PDCD6IP ETV3 IRF8 IDS HOMER1 NAA30 MOB1A TMEM192 BLOC1S6 CD164 MRPL39 EXOC1 GNA13 HACE1 SERTAD1 RTN4 TAB2 G3BP2 CTSC ZDHHC5 KLRK1 LDLR PPP1CB HAT1 HTRA2 FHL5 CD70 CHIC2 TBPL1 ENDOD1 ITGB1 NOG PIAS2 UBE2N PDE7B	down	***
GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP	0.0000594	0.0006282	0.5573322	-0.3134285	-1.649826	170	USP12 SIK1 RUNDC3B TMOD3 CALCRL CTDSP1 NR3C1 DENND2C ZBTB4 CNST PKD2L2 GM2A FOXP1 PAG1 LAIR1 PPP3CA BTG3 DENND6A PRKD3 GAPVD1 NR1D2 PPP2R5A IL7R PIK3R5 TP53BP2 FAM102B BTG1 CREBRF SGK1 IFNGR1 PTGER4 CCR7 DDX5 GPR183 RC3H1 CD7 RNF24 RUNX3 MTMR2 PHF2 CLCN6 SESN1 MIER1 IER5 ALDH2 TDRP ZNF471 FAM13B SMAD4 ZBTB40 CFL2 CDKN1B ATP11B ALG2 ATP1B1 ATP8A1 RCBTB2 SMIM4 KLHDC1 ITGA6 NEXN FAM78A CD226 CFLAR ZFP1 BICD2 RCAN3 ARID3B ATP10D LATS1 TMEM64 AMPD3 PADI2 RARA XPO4 VIPR1 RASSF3 BCL11B IFIT2 STAR AMZ1 VPS37B PPM1B IL27RA IL6ST NRIP1 AAK1	down	***
GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP	0.0002474	0.0021066	0.4984931	0.3694036	1.649162	164	CDHR2 STAC2 GPT PKP2 MCM10 ELOVL6 NEK2 APOLD1 KIF18B CDCA7 RACGAP1 ANLN ABCA12 BCAS1 AURKB CENPA TPX2 MYBL2 MIS18A MYL6B MKI67 DCBLD2 KIF2C CHAF1B LMNB1 XXYLT1 AIMP2 BRI3BP TXNDC5 CKAP2L TIMM50 PERP EEFSEC IDH2 MBOAT1 SLC25A10 PPIL1 CDK1 E2F1 CTXN1 KPNB1 NET1 CRLF1 CCNE1 DLGAP5 NEK10 NADK2 LMF1 ROGDI DNM1 TYRO3 LSM14B CKAP5 TUBG2 BEND6 CDR2	up	**
GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_UP	0.0001193	0.0011304	0.5384341	-0.3149005	-1.648771	160	TMEM150B CPEB2 FABP4 LPXN CGNL1 MYD88 BMPR2 CTDSP1 IL1RN GAS6 FRAT1 LMNA NAAA HSPB1 RNF144B PAG1 ANKRD29 TFRC CSRNP1 CCDC82 SORBS1 AFAP1L1 TMBIM1 DUSP1 ALOX5AP CCDC59 ADIPOR2 USP25 UFM1 DDHD1 JUN MTMR14 IFNGR1 STX5 CD164 STXBP3 NAB1 GATA6 ABL2 CXCR4 VPS4B ZNF471 SSH2 ULK2 CEPT1 DOCK10 EIF4A2 CNN2 KLF15 CHP1 HIPK1 SLC26A11 MT1E FAM160B1 SNX14 MFSD1 MTSS1 RCSD1 ARHGEF12 ATP8A1 RAB39A WDR26	down	**
GSE3982_MAST_CELL_VS_MAC_DN	0.0001826	0.0016383	0.5188481	-0.3146294	-1.648640	165	EPAS1 KMO USP12 FABP4 SLC6A12 ENG BAG4 PCOLCE2 EPB41L3 SCARF1 DDO PILRA TEX2 GGA2 DNAJB14 CD36 MAN2B1 MTF1 HLX TUBB6 PPT1 DAB2 SLC7A8 TMED5 RMDN3 SPAG9 CAPZA2 INHBA MATK CLIP4 ZNF706 RABGGTB CTSS PHACTR2 RAB8B SERPINB8 JUN MITF ZNF804A CXCL5 RHOQ PSMD12 FOXO3	down	**
GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP	0.0000620	0.0006527	0.5384341	-0.3119852	-1.648028	174	OSBPL11 THBD S1PR1 TBC1D2 GAS6 LAMP1 WWC2 RRAGC SLC36A4 RNF144B ABCG1 CD93 SPRY2 TMEM41B ATP6V1B2 FBXO8 RHOB LRP4 PTPN21 KIAA0513 LEPROTL1 CEBPA NR1D2 CDS2 TM6SF1 CD300C MFSD11 CPT1A NRBF2 ANXA3 PI4K2A CNRIP1 VWF GLB1 MYLIP PGD CD48 SLC10A7 APH1B WDR7 SLC3A2 ATP6V0D1 YPEL2 C19orf38 TIMP2 TESK2 TEC TMEM230 NQO2 RGS2 MFSD12 PLA2G15 ZNF438 MTO1 METTL21A G3BP2 HEBP1 LPAR6 EHD4 PHYH TMEM50A ZBTB16	down	***
GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0002848	0.0023514	0.4984931	0.3741820	1.647242	146	TICRR IGF2BP3 KIF18B FOXD4 TTK PLK1 FIGNL1 KNOP1 UMPS MCM8 NCAPD2 PUS7 AURKA IL12B WDHD1 FANCD2 ORC6 CBY1 SPC24 PPP5C CNPY2 TXLNB CENPH PSAT1 KSR2 LIPT2 KPNB1 EIF6 EFTUD2 MZT2B NPHP1 PSMA5 PUS1 MLF2 MRPL52 IQCG HMGN3 FAM207A TIMM13 WDR34 GPATCH4 THOC5 UTP20 TMEM147 CLUH SRSF1 LSM4 PRMT5 GRHL1 UQCRC1 SEC13 OXCT1 ZMYND19 TARBP1 PGAM1 TARBP2 MTHFD1 NMT1 TBL3 TMEM42 FTSJ3 TMEM161A BCKDK EIF2B1 ZC3HC1 LCMT1 PSME1	up	**
GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN	0.0001139	0.0010939	0.5384341	0.3664069	1.645630	175	KIF1A CNGA1 ADH1C ELOVL6 PSPH BRCA1 RACGAP1 ANLN CDCA8 CCNB2 MCM2 MYBL2 PRC1 HAUS5 RANBP1 BZW2 NUDT1 F2RL1 TOP2A MCM7 MPHOSPH9 MRPL27 CDC25C SLC12A7 RBP1 CHEK1 MAD2L1 AHCY PFKP XRCC1 CKS1B DRC1 NUSAP1 CDK1 BIRC5 SRCIN1 TCF20 PSAT1 PDK1 EZH2 SEMA4F COL1A2 PSME2 KIF22 SSRP1 MYBBP1A MMP7 HLA-A ZBTB7B CENPK CPSF4 PSMB3 CDC20 MRPL41 CKAP2 NFE2 CBR1 AP2S1 CCNA2 MRPL55 RFC5 LPIN1 RAD51 UQCRQ GOSR1 NPTX1 DHRS3 FRMD6	up	**
GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP	0.0000703	0.0007305	0.5384341	-0.3120635	-1.645405	173	SLC6A4 EPAS1 SECISBP2L FABP4 ENG TMOD3 SAMHD1 BAIAP2 MYD88 TLCD2 CHRNE PBX3 FOXP1 RGCC MTHFR RAB12 FOXO1 KCNMA1 NES STX3 VRK2 CCL4 PNRC1 WASF3 ARL4A CPT1A SH2D2A TANC1 KREMEN1 NCOA1 NSMAF MED28 COPS2 NXF1 INMT ST6GALNAC4 GSTO1 SNX2 CD83 STX5 TSPYL1 CD164 RUNX3 RELL1 PIM1 SLIRP BRI3 IST1 JUND ICAM1 TAB2 UBE2D1 TBC1D1 FBXO25 PSME4 STAM2 KATNA1	down	***
GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN	0.0004523	0.0035086	0.4984931	0.3670420	1.644189	169	EGLN3 CCDC34 CENPF DDIT4 ANKZF1 TRIB3 SPINT2 CDC25A CCNF DNAH14 RUVBL2 EXO1 SPAG16 CENPW WDHD1 PLTP CHAF1B DNAJC9 BLM GLE1 IDH2 PAK1 MRPL37 DTD1 CENPJ TRAP1 MRPL17 KIF2A FEN1 FADD LRRC42 SAPCD2 MAD2L2 RECQL4 POLR2H DNMT1 VBP1 DNAJC17 RHOC MTA3 TK1 DTYMK SND1 POLB YARS2 P4HA1 DHRS1 NFXL1 IARS2 ZCCHC17 FAF1 FBXO22 PPCDC MCM5	up	**
GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN	0.0000768	0.0007891	0.5384341	-0.3097892	-1.644051	176	SLC6A4 OLR1 SNX10 HCAR2 PLEKHF2 TXNL1 GTF2E2 USP47 ZEB2 GINM1 ANXA1 SSTR1 PPP1R15B CHMP1B NMUR1 BFAR GPBP1L1 SERPINB9 MCL1 TMEM38B KCNMA1 BNIP2 CDIP1 GCA CPT1A WFS1 PPP2R5A PEF1 CMTM6 KREMEN1 PI4K2A TDRD7 CREBRF WASF2 NKD2 ESD PLEKHA3 MTMR14 SNHG8 SNX2 FBXO11 HOMER1 TSPYL1 GFPT2 TMEM192 BLOC1S6 CACYBP	down	***
GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP	0.0001197	0.0011322	0.5384341	-0.3100527	-1.642509	175	TMEM126A HSD17B11 EGR2 NEDD9 BCL2A1 CD9 ANXA1 PTS ASAH1 ABCG2 LITAF CD93 CRTAM CYP4V2 TMEM38B EPB41L2 AHNAK CASP1 YBX3 ITIH5 NFKB1 ARAP3 FCER1G EVI2A CPT1A ADIPOR2 N4BP1 NUS1 HSDL2 RBPJ PHTF2 CD160 NSMAF GABARAPL2 SNAP23 SH3BP5 KCTD12 ETS1 TYROBP VPS26A GSTO1 EEA1 IRF8 SNX1 AP3B1 TNFRSF9 AGFG1 RHOQ IRF5 TSC22D1 KHDRBS1 PDCD1 CD81 GABARAPL1 ACADL DECR1	down	**
GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN	0.0001497	0.0013923	0.5188481	0.3657445	1.641613	177	KIF20A CDC45 MCM10 NEK2 UBE2T PRIM2 BRCA1 TTK E2F8 ANLN ASPM CDCA8 AURKB CENPA IGLC7 ECT2 CDC6 CCNB2 TYMS PRC1 CCNF DTL CISD1 CHAF1A MKI67 BUB1 TOP2A AURKA KIF2C CDCA5 GCAT KIF11 CDC25C LIG1 CHEK1 MAD2L1 PERP GNPDA1 INCENP CKS1B CDKN2C NUSAP1 ASF1B CDK1 BIRC5 GMNN EZH2 DLGAP5 TACC3 KIF22 TK1 GALNT3 FHL2 RHD	up	**
GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN	0.0002560	0.0021613	0.4984931	0.3652533	1.640833	171	NUP107 POLQ SORD ACAD9 SFXN1 UHRF1 HPS3 RCCD1 GSDMB MAGEF1 GOLPH3L KCNN4 EME1 SYNE4 FSD1 PKM EIF2AK1 LMNB1 B3GNTL1 LETMD1 CAPN12 BRI3BP SARS2 PSMD4 RAB13 PIH1D1 GEMIN7 NOL3 DLG5 C12orf75 CMAS NSF UCK2 NUDT2 ACP6 ZNF775 MAD2L2 SRD5A1 ANKRD39 UNC45A RHOC C12orf45 COMMD7 MTA3 ARF5 PINLYP TCEA1 FUCA2 NUP85 STOML2 ASCC1 ZNF558 GINS3 CEP152 ABHD10 UQCRC1 ZSCAN22 MICU1 CDK5 ETHE1 ALKBH6 CDC25B MRPL48 PARP2 CLNS1A CAMK2G JAKMIP2 SRI PSMB10 MTMR4 RNF144A TCEA3 DHX32 STXBP1 CS TXN2	up	**
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_DN	0.0005331	0.0039776	0.4772708	0.3745824	1.640672	139	PPM1H CCL19 HNF1A SLC16A14 BDH1 LHB C5orf46 TTC26 EFNA4 BCL2L14 XDH CDT1 SLC4A8 THBS4 SYCP2 POC1A RHOBTB3 HOOK1 AMACR SMYD5 DNAH8 KLHL35 SAMD10 DNAH6 MCTP2 WDR54 SPACA4 FAM98C ENPP3 FEN1 TMEM79 MTBP TMEM51 TAPBPL ARHGAP32 ZMAT5 CADM4 CASP7 PCDH9 ATP13A1 NR6A1 SLC26A1 RRP9	up	**
GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP	0.0000951	0.0009344	0.5384341	0.3657234	1.640573	173	FOXM1 CDC45 FANCI IGF2BP3 KIF18B CLGN SORD BRCA1 E2F8 TSPYL5 STIL COPB2 MIS18A MYL6B STAG3 RPL39L KIF15 TP53BP1 PCCB NUP155 POLA2 MCM7 LMNB1 SALL2 PSMD4 DSCC1 TSHR EFCAB11 CBX5 CEP97 TNFRSF21 FAT1 PLCH1 C1orf112 GMNN SPAG5 FADD TMEM231 KPNB1 CHCHD3 TAPBPL PSMA5 ARHGAP32 SAP30 DNMBP SND1 MARCKSL1 CDC20 ASRGL1 PEX5	up	***
GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP	0.0001139	0.0010939	0.5384341	-0.3111909	-1.640343	172	CD52 SWAP70 ACE CD55 HHEX CYP27A1 LPXN GPR65 LIPA SLC6A12 CD44 LY86 RGS9 CD1C GGA2 SIGLEC6 NDUFAF1 SLC7A7 NAAA MAP3K8 IFI30 HSPB1 MS4A1 TFRC TXN TBC1D9 PTPN21 AHNAK KLF9 STX3 LY96 SELL CCL4 ALOX5AP PLEK EVI2A MATK PKIG PNO1 SNAP23 CD48 SH3BP5 MAP4K4	down	**
GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN	0.0001217	0.0011491	0.5384341	-0.3105933	-1.637193	172	OLR1 TMEM170B WDR74 AQP9 IL1RN OTUD4 EPB41L3 MOB1B RFTN1 RBM7 NFIX TRA2B CLN5 TCF7L2 MTHFR FOXC2 PTPN12 PPM1K TJP1 SOCS2 PER2 CDKN1A GPR85 CCND2 WFS1 UNC5A BACE1 RSRC2 PIAS1 PHTF2 APPL1 SRSF3 MITF ETS1 ELP5 FOXN2 TBC1D12 SKIL ZCCHC9 TMEM128 GPRIN3 PDS5B CD86 C16orf72 STK40 MICU3 PGGT1B PTCH1 RND1 NRP2 ZFPM2 MT2A ATF4 DNAJA2 PPP1CB CSF2 PSIP1	down	**
GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN	0.0001341	0.0012592	0.5188481	-0.3137135	-1.636876	168	GPR15 USP12 SOWAHC OTUD1 TMOD3 CCRL2 ST3GAL6 HEATR5B GTF2E2 PAFAH1B2 TRIB1 ABCB1 SEMA6D FAM89A JAM3 NDEL1 TIPARP CSRNP1 PTPRO PPM1K PLAUR TMED5 CLIC4 GPR85 ATF3 VIM AXL CCND2 FRMD4A RNF139 HSDL2 PI4K2A RASGEF1B IL6 OASL CPEB4 RHOG ENPP4 GLIPR1 CGGBP1 TOM1L2 STXBP3 GSAP PDCD1 TAGAP TSPO SETDB2 SETD4 TRAF1 TMEM184B KATNA1 LYST TNFSF9 SYNPO2L THEMIS2 GIMAP4	down	**
GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN	0.0000881	0.0008846	0.5384341	-0.3083751	-1.636546	176	SNX10 HSD17B11 DDX6 INPP5A DYRK1A BCL2A1 CD9 CD22 SPG21 RANBP9 MS4A1 IL18R1 CYP4V2 MCL1 EPB41L2 AHNAK CASP1 ITM2B RRM2B ATP6V1D SELL M6PR EPS15 DUSP1 PPP2R5A VAMP5 IL7R HLA-DQA1 NXF1 ETS1 ATP11A SNX2 CCR7 CD83 ENTPD4 RASSF2 RRN3 CD6 SBF2 RELL1 TOB1 PPID PDE4B CCR6 GLTP RNF138 WDR1 TPT1 SLC25A20 ARIH1 CREBBP CD19 ARPC5 SKI DNAJB9 IL16 EIF4A2 SMAD4 DNAJA2 EIF4G2 CTSH ITGB1 ZFP36 AKAP12 MATR3 SKAP2 ITGA6 RNGTT CFLAR PKD1 TTC39B CD4 ANKH MFHAS1 IL10RA CYTIP RCAN3 TMEM71 CD47 FASLG B2M LUC7L	down	***
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP	0.0013211	0.0085006	0.4550599	0.3755812	1.635552	133	STYK1 HHLA2 VWDE HELLS UGT8 IGF2BP3 TOX3 FABP6 PLD5 GLDC PLS1 AK8 GPX2 APOL1 POLA2 FNDC5 SP140L EGFR PERP STAT2 CDH3 NAPEPLD GBP5 SNCAIP CHST3 PSME2 ENAH ZNF239 ATG9B FHL2 IQCH POLB CCDC137 MDGA1 HHLA3 PARP14 RGMB SCO2 GBP1 TUBA4B GBP2 DNPEP WDR76 TRIB2 LINC00205 LRRC4C SLC35G1 RIMS1 NLRC5 KCNK6 DYNC1H1 TRAFD1 ST6GALNAC1 TMEM229B HINT1 ZNF276 PSMB10 RSAD2 BAK1	up	**
GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN	0.0001143	0.0010939	0.5384341	0.3643691	1.634497	173	EGLN3 CCDC34 DROSHA SORD ANKZF1 CDC6 STC2 SPINT2 APOL2 EXO1 SPAG16 DPY19L2P2 STAP2 FANCA LGMN MPHOSPH9 PKM CHAF1B ORC6 MAD2L1 ETFA REPIN1 BLM GLE1 SKP2 ASF1B PAK1 DTD1 KIF2A MAD2L2 ITPR3 UNC45A CHCHD2 PIAS3 SNRNP25 VBP1 GNPAT SNRPA LMNB2 OSBPL3 MRPL52 TMEM237 GFM2 P4HA1 CENPM FBXO22 ZNF248 MCM5 SIRT5 TMUB1 FARSA LRP11 CCNA2 VDAC1 SHCBP1 UQCRC1 WDR76 VDAC3 GMPR2 PAICS NCAPD3 E2F7 C4orf46 IFI16 CLNS1A TFB1M APEH DRG1 MRPS16 FAM120A TRAFD1 CRAT MTMR4 HDAC3 TIPIN PLEKHJ1 KEAP1 TXN2 NUP37 PFKL RBX1 COA6	up	**
GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN	0.0000675	0.0007044	0.5384341	-0.3070434	-1.633198	187	WEE1 RAB11FIP1 OSBPL11 GPR65 RAPGEF2 CLDND1 TGFBR3 TRIB1 ANXA1 UBL3 ENTPD1 PICALM TTYH2 STOM AKT3 SRGN CD58 EVI2B AHNAK LIMS1 ARNTL VRK2 SPAG9 ITPK1 COTL1 PAPSS1 FXYD7 SLC6A6 DEGS1 KLRB1 PHACTR2 AQP3 RAPGEF1 GPR183 TAGLN2 TIGIT GPRIN3 CD74 AKIRIN2 PEA15 DUSP5 ATXN1 TERF2IP LGALS3 CCR6 CDC42EP3 EPHA4 ARHGAP18 S100A4 CTSC KIF1B RORA NABP1 IQGAP1 EMC3 EHD4 RSU1 PIEZO1 HERPUD1 SPSB1 SPPL2A SH3BGRL3 ITGB1 SH3GLB1 FAM53B HLA-DRB1 RNF214 ATP2B4 MAP3K1 NCOA7 RNF19B MYO1F MYO5A CBLL1 ADAM19	down	***
GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN	0.0005730	0.0042363	0.4772708	0.3648660	1.632681	166	MMP13 FOXM1 HELLS MCM10 NUP107 MND1 AGFG2 IQGAP3 EBF3 PTTG1 CUEDC1 RAD54B TYMS DLGAP1 WDR90 TNC LDHB RUVBL2 NOS1AP EXO1 ZFYVE27 AGT MCM7 ABCC5 RAD51AP1 PIH1D1 PKMYT1 BRIP1 RAD18 BLM ZCRB1 CKS1B LRRC6 FAT1 E2F1 EZH2 SEMA4F MOV10 INTS7 CEP192 DCAKD LMNB2 TRIM37 SUDS3 COPS7B GINS2 POLD1 CCT7 SH2B1 CENPT SNX11 TMUB1 CDH11 CEP152 DTNB ARRDC1 TNKS1BP1	up	**
GSE36826_WT_VS_IL1R_KO_SKIN_DN	0.0001846	0.0016537	0.5188481	-0.3113578	-1.632590	166	CD101 OLR1 SPN PID1 EMCN BACH1 AQP9 C5AR1 RBM14 CDC42 RFTN1 CD5 MTF1 ANPEP SLC7A11 LCP1 SLC25A37 MCL1 CD58 THBS1 SCAF4 CDKN1A COTL1 VIM CD53 DUSP1 DSE SRF EMP3 FRY PSMA1 TREM1 RHOG PPP1R15A IDS CDK2AP2 REL CGGBP1 CST7 PPM1F CDK14 SLC3A2 HNRNPA2B1 NAB1 PITPNA TXNDC15 MGAT2 ITGAE ACTB TRAF1 SRSF10 PDE4A DNAJB5 EIF4G2 PPP1CB AFTPH DUSP6 SH3BGRL3 TMEM43 FHOD1 FPR1 PTGS1 GNG11 LAMP3 DDX21 TES STARD5 IRF4 MSC GPATCH2L EMP1 PNP	down	**
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_DN	0.0008974	0.0061232	0.4772708	0.3718094	1.632561	141	SYT8 GRIK2 FOXA3 CUZD1 KCNK5 GABRB3 FAT2 GPR35 BAIAP2L1 C4orf19 ARHGAP33 MARVELD3 DZANK1 MYL6B SHC2 RSPH1 CYP24A1 TIMD4 MSX1 TRPV6 SDK1 TOM1L1 OAZ3 HHIPL1 GEMIN7 SPAG8 RECQL5 NRTN C2CD4C SPATA6L DNAH6 C16orf71 ANKRD55 ATP7B HIRA PAPLN ZNF239 KIF21A HIP1R MAP6D1 ACSL6 DHTKD1 CADM3 HPD	up	**
GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN	0.0001672	0.0015345	0.5188481	-0.3113842	-1.632477	171	SLPI ARHGAP31 IL1A CXCL16 FBP1 LONRF1 FLVCR2 BCL2A1 IL1RN SCARF1 HPS5 ZEB2 HSPE1 EIF4A1 RRAGC B3GNT5 MCTP1 ADAM17 MTF1 STOM TXN LIMS1 PLAUR ATP6V1D UBQLN1 DPH3 CD53 PRF1 PROCR KLRB1 GABARAPL2 PHACTR2 PSMA1 STAT4 GIMAP2 GSTO1 WTAP PI4K2B ATP13A3 RRN3 PIK3AP1 DDX18 AZIN1 PDE12 LRRC32 SOD2 KYNU ETS2 PITPNA MOB3B HSP90AA1 SRSF10 NFKBIA CD1E FNIP2 SMPD1 SLFN11 SPHK1 MB21D2 C1QB CLEC4E COX20 CALR FPR3 CCDC93 SERP1 IRF1	down	**
GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0004881	0.0037158	0.4984931	0.3716354	1.631909	143	SPATA24 MCM10 NEK2 IQCE PBK THOC3 IFT122 KIF14 CDC6 UHRF1 ARHGAP33 FERMT1 MKI67 TSGA10 CCDC77 MPO TGM1 PPP5C FADS2 SYMPK BTBD2 PARP1 PES1 TMED3 ASF1B HDGF EXOSC2 RAPGEFL1 IGSF3 CBX1 CHST3 NMRAL1 SSRP1 HECTD1 SLC22A23 SEC14L2 EPN1 CENPV GID8 TMEM147 ZRANB3 RFC5 CARHSP1 PPP6R2 TAB1 TARBP1 CPOX UQCRQ SIRT6 ADCY6 TMEM256 SNRPC UBTF ZFPM1 SLC40A1 TUBGCP2 STARD10 GLRX5 ABCD3 CS PPA1 COX6A1 RAB3IL1 EXOSC7 BUB3 EDC3 GATM CLPB	up	**
GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN	0.0001058	0.0010251	0.5384341	-0.3071641	-1.631861	179	EPAS1 ACP5 STAC PPARG FBP1 CYP27A1 DCSTAMP TRPV2 ENG CORO1C ALAS1 LAMP1 PFDN1 AVPI1 HSPE1 NDUFAF1 ARSB LMNA GM2A CSRP1 CYB5A HSPB1 CRTAM TFRC SETD3 FABP5 ACSL3 PXDC1 PARVB ATP6V1D RMDN3 CLIC4 CTSD PAPSS1 EFR3A PI4K2A HEXB TECR MITF VAT1 ST6GALNAC4	down	**
GSE6259_BCELL_VS_CD8_TCELL_DN	0.0001672	0.0015345	0.5188481	-0.3111577	-1.631290	171	AKAP5 MS4A7 TAL1 RAPGEF2 PTPRE LONRF1 IDI1 CIR1 YPEL5 FRAT1 ERG TNIP3 PICALM NLK FZD4 TFEC MYCT1 PPM1K YBX3 ST3GAL2 NR1D2 HES1 AFF1 TANC1 MAPRE2 FAM102B NRROS BTG1 CREBRF HECA GAS2L1 CARD8 IFNGR1 PNPLA8 MBNL2 HERC1 RHOQ YPEL2 IRS2 HBP1 TAGAP MEIS1 PHLPP2 BMP2K IER5 CEBPD CXCR4 FBXO25 NUP98 METTL7A NPAT STK4 FDFT1 GRB10 ZBTB44 PSIP1 DUSP6 CCDC112 SLC38A2 FAM8A1 KIAA2026 PIK3CG	down	**
GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN	0.0000877	0.0008841	0.5384341	-0.3058740	-1.631157	182	LRRFIP1 EGR2 GTF2E2 RBM14 S1PR1 BCL2A1 HPS5 ATP2B1 HBEGF PAQR3 EIF4E IL18R1 NFE2L2 NDEL1 SRGN CD58 MAP2K3 ADO PER2 NFKB1 ATF3 CCL4 SH2D2A PPP2CA PNO1 GABPA CYCS RHOG TMEM251 IPO7 IFRD1 SP3 NOL7 ACSL1 BAZ2B TEX30 DUSP5 GNAI1 ATP6V1A NAB1 GNG5 CD81 UTP3 PGGT1B MBNL1 GEM ANKLE2 IL18RAP WDR1 CDC42EP3 RIPK2 UBE2D1 TRAF1 STK4 ZNF165 PSMD9 NUP160 FEZ2 ARFGAP3 EIF4G2 SNRPG ICOS WDR47 GABPB1 KLHL9 CFLAR GTF2H1 IVNS1ABP PNP RANBP2 TNFRSF1B GNL2 SUCLA2 KLRG1 CYTIP PSMD14 TRPC6 EZR AGO2 PGAP1 CD47 PTPN22 SACS SEC62	down	***
GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_DN	0.0015643	0.0095783	0.4550599	0.3915378	1.630509	99	GPR156 FAM83B GRIK2 HOXD8 RGMB-AS1 TTK BRSK1 TMEM254-AS1 DTL KHDC1 DNAI1 WDR62 GPR37 CBLC ZNF112 FSD1 HHIPL1 SOX11 SPC24 GRHL2 SYMPK APLP1 DMGDH NCAPG STEAP1 KSR2 PRR22 UPP2 COL5A2 TSPO2 AKAP8L GINS2 CHRD KCNB1 CD2BP2 MMP24 FRY-AS1 ZNF257 TMC2 FRZB CNTNAP3 BFSP2 C4orf46	up	**
GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN	0.0000835	0.0008498	0.5384341	-0.3097387	-1.630404	170	LPIN2 SLC12A6 GIMAP8 OTUD1 LMO2 YPEL5 C8orf58 HPS5 RCHY1 GGA2 CASP9 PDE2A ZBTB4 B3GNT5 LATS2 KLF6 MS4A1 CLK1 HERC3 RRM2B STK17B CDS2 HPSE PNRC1 CLK4 CD53 MBD2 LMBRD1 HEXB BTG1 MYLIP CREBRF FRY GZF1 C20orf194 ETS1 OSBPL9 DDX17 EPC1	down	***
GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN	0.0001225	0.0011544	0.5188481	0.3632127	1.629310	173	HJURP FAM81A RUVBL1 GMDS FBXW8 CDK4 SPP1 EIF2B5 PMS2 EIF3B SHMT2 SIMC1 TMEM41A NUDT1 MKI67 F2RL1 WDR3 POC1A TRRAP PASK FANCD2 SLC12A7 GLE1 PPP1R37 GPX8 CKS1B C1orf112 ACP6 SCTR KIAA1211L ATAD3A KCTD1 DAP TELO2 TACC3 LONP1 OSBPL3 PTGES2 SSRP1 MLEC FHL2 ELAC2 GTF3C1 DGKA ACLY MCM6 WDR83 LTV1 HMCES SKAP1 TXNL4B NME7 SMPD4 MON2 GPX7 SYNE2 ANKRD46 NELFA CNPY4 EIF2D POLRMT RANBP10 ZNF598 HINT1 MEX3D SNHG17 NHP2 RCC2 WDR89 TXN2 PPP2R1A NBAS EBNA1BP2 CTPS1 PRRC2B MIEF1 MPLKIP	up	**
GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN	0.0003091	0.0025269	0.4984931	0.3661308	1.629301	161	LINC00342 CABIN1 MSTO1 PTTG1 SPATS2 GLDC GON4L LIME1 COQ3 LDHB P4HTM GTPBP3 IGLV1-44 MCM7 MPHOSPH9 FANCD2 CHD6 ORC6 ADCY10P1 COX19 TMEM63A AKT2 SYMPK ETV7 DDX51 VN1R1 TNFRSF25 PKD1P1 IGHG1 PAXIP1-AS1 PDK1 C16orf71 METTL3 HMGXB3 FGFR1OP ZNF500 GRAMD1A PABPC1L IGLV6-57 SPG7 MSI2 HECTD1 ITFG2 ENOSF1 DENND5B FAM71E1 DGKA SRSF1 STMN3 PDIA4 ZNF274 AMN1 GABPB1-AS1 GTF3C2 CDK5RAP1 SNRNP70 SNRNP200 TCF3 IGLV3-19	up	**
GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP	0.0001738	0.0015755	0.5188481	0.3625276	1.629212	176	FOXM1 HELLS CDC45 MCM10 BUB1B DNAJC12 CENPF POLQ PBK BRCA1 PHGDH E2F8 HILPDA AURKB ECT2 ESPL1 CDC6 SFXN1 TRIB3 CDC25A COCH CCNF DTL ZWINT MYL6B COQ3 TNC KIF23 AURKA THBS4 WDHD1 GPSM2 CHEK1 MAD2L1 DLG5 CBX5 MCTP2 DNA2 SPAG5 DLGAP5 SCLY TRADD KIF22 GINS2 FHL2 ELAC2 IP6K2 PPCDC NOC4L SUOX MARCKS CCNA2 SHCBP1 RAD51 TPGS2 SUPT3H NME7 SMC2 COPZ2 GPN1 RASGRP1	up	**
GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN	0.0002999	0.0024596	0.4984931	0.3616723	1.628467	180	NEK2 C17orf75 MPP6 PBK KIF18B PIF1 TBRG4 E2F8 ANLN POLE AURKB TYMS UMPS PRC1 GLDC GRB7 NME1 RANBP1 MRPL15 CLHC1 EME1 POLA2 PDCD5 AKAP1 RAD54L KIF11 AIMP2 LIG1 CHEK1 MAD2L1 GNPDA1 PPIL1 INCENP CKS1B RFWD3 CENPH SRCIN1 SDCBP2 ETFB CENPP CCNE1 ALDH7A1 TACC3 KIF22 TRIM37 CASP7 SCN8A MLEC HLA-A PROX1 GEMIN6 HNF1B ASRGL1 NMNAT1 MALSU1 LHPP RAB34 CCNA2 CISD3 BANF1 RFC5 RAD51	up	**
GSE7509_DC_VS_MONOCYTE_UP	0.0001501	0.0013928	0.5188481	-0.3061955	-1.626445	177	TSPAN4 LTA4H THBD LPL HSD17B11 LY86 SRSF7 ARL8B ALAS1 ANXA1 HBEGF ENTPD1 GM2A ANXA5 LITAF CST3 FABP5 NES DAB2 PLBD1 CTSD CADM1 ITGAX ATF3 PER1 ACTG2 IL7R PTGIS PI4K2A GLB1 HGSNAT RPS6KA2 DCTN6 C1QA ST6GALNAC4 UVRAG CEBPZ FOXO3 NDUFA5 TEC UTP3 LGALS3 GABARAPL1 RGS2 GTF2B SESN1 GSTM5 CDC16 CDKN1C TMEM109 TIMP3 PSMD6 CREG1 CNN2 UBAP1 SPSB1 CSF2RB C1QB CRTAP CTSH	down	**
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN	0.0000898	0.0008946	0.5384341	-0.3089721	-1.626369	170	ABHD5 MNDA SNX10 TRPV2 MYD88 STX11 ALAS1 IL1RN PSMD5 SPG21 GRN TXN TUBB6 ATP6V1B2 TBC1D9 KIAA0513 CASP1 PTAFR PLAUR STX3 RMDN3 CLIC4 CDKN1A CDS2 INHBA DSE USP25 PGD RAB31 HK3 ATP6V0B TYROBP DNAJA1 KLHL18 OGFRL1 CGGBP1 ACSL1 RHOQ ATG3 RIN2 SORT1 DUSP5 CD86 ATP6V0C SOD2 CCR1 KYNU GEM SLC31A1 RTN1 LRP12 CALCOCO2 NLRP3 GLRX2 MT2A CREG1	down	***
GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP	0.0003717	0.0029593	0.4984931	-0.3179802	-1.626236	139	KLF13 EGR2 RASAL2 KIAA1109 STX11 TRIB1 SLC44A2 MAP3K8 NR4A1 UBE2D3 ADAMTSL4 MEFV FAM124B SNORA30 NFKB1 PER1 CPT1A PTH1R ETV3 ARL5B DDX17 PPP1R15A PTGER4 GPR183 CREB1 REL DEDD MCAM FOS GSAP TGIF1 NAB1 PDCD1 TAGAP GPR18 DBNDD2 ICAM1 ARAP2 YAF2 SSH2 SDAD1 NFKBIA CTSC TTC19 SAMSN1 VPS13D EGR1 FPR1 NDFIP1 CSNK1G3 CD69	down	**
GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_UP	0.0005268	0.0039540	0.4772708	-0.3268314	-1.625679	123	SLC6A4 SMAD6 TMEM100 FGD5 OSBPL1A MMRN1 SH2D3C KCNAB1 HBEGF SLC7A7 ZBTB8A TCF7L2 APOC1 SLC46A2 KCNK17 GCHFR SLC38A11 ID3 CEBPA RMDN3 EPM2A ID2 ALOX5AP SMAD7 INSL6 SPIN1 SCN4B CNNM2 INMT DNASE2 SKIL	down	**
GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN	0.0001663	0.0015315	0.5188481	-0.3068222	-1.625396	175	TUBD1 OSBPL1A MMRN1 ASAP1 MCTP1 MTF1 KLF6 MPHOSPH6 CRK CCNI ROCK2 DUSP3 CASP1 RNFT1 DAB2 KLF7 SCAF4 PDE8A RBMS1 SELP KCTD20 CD53 ADIPOR2 GNAQ KPNA3 LMBRD1 NCOA1 PIAS1 TBC1D5 MOB4 RBPJ ARL6IP5 CDC40 GABARAPL2 ESD PSMA1 GSTO1 FBXO11 GMFG REL AP3B1 UVRAG POGLUT1 SPOP SAV1 STRN MR1 SYT11 CPQ ARPC2 CALCOCO2 C21orf91 PAPSS2 AFTPH PUS3 TMEM50A SAP18 EXPH5 CLOCK	down	**
GSE3982_DC_VS_BASOPHIL_UP	0.0001802	0.0016231	0.5188481	-0.3097449	-1.623883	171	KMO SIDT2 PPARG LTA4H TRPV2 CYB5R3 PCOLCE2 CD1C DDO CD36 MAN2B1 ASAP1 HBEGF GM2A ABHD6 RGCC TNS1 GRN SPRY2 ATP6V1B2 ATP10A IL10 SNED1 CCL22 ADO GAA DRAM1 ATP6V1D PDE8A LAMC3 PER2 ATF3 ZBTB43 INHBA MATK CLIP4 ZNF706 GLB1 HCK ESD C1QA HUNK CD83	down	**
GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP	0.0002102	0.0018518	0.5188481	0.3616026	1.623022	177	KIF20A HJURP CDC45 FANCI CCNB1 NDC80 RACGAP1 E2F8 SPP1 ALDH18A1 GPI TPX2 CCNB2 MCM2 CDC25A ZWINT RANBP1 CEP55 MKI67 PCCB SLC22A18AS GPSM2 DNAJC9 DET1 COQ9 PARP1 NCAPG2 NUSAP1 ATIC NCAPG MRPS12 PSMC4 VBP1 ILF2 DPP3 TUBG1 AARSD1 TUBB2A PSME2 TUBA3D ROGDI TK1 CLTA MAGOHB PEX10 TSTA3 ACLY MCM5 AATF NT5DC2 PRIM1 HK2 TTC1 SEC13 COX5B PGAM1 UQCRQ SPR NMT1 PAICS UBE2C COX17 APOBEC3B APEH LASP1 PSTPIP1 FBXO5 ABHD2 BAK1 TMPO GTF2F1 COX6A1 EIF4G3 P2RY6 COPS7A IPO4 PSMD8 DEF6 ACOT7 COX6C P4HA2 WDR12	up	**
GSE30083_SP3_VS_SP4_THYMOCYTE_DN	0.0001129	0.0010915	0.5384341	-0.3076177	-1.621963	173	FAM167A ST8SIA6 HHEX ZC3H12C SNX10 CD44 LY86 CTSW CLEC10A IL1RL1 TEX2 GM2A LITAF CYB561A3 LAIR1 IL18R1 GRN SPRY2 CYP4V2 RHOB EVI2B AHNAK MPEG1 CASP1 RNFT1 RRM2B HOPX HPSE PLEK KLRD1 DSE UBASH3B TDRD7 TBC1D5 S1PR4 SGK1 IL2RB STAT4 TYROBP IRF8 FAM43A TBX21 RHOQ NKG7 RIN2 PEA15 KCTD10 KCNN2 ZC3H12D TAGAP N4BP2L2 RXRA GEM IL18RAP IER5 ITGAE	down	**
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP	0.0001900	0.0016890	0.5188481	-0.3093664	-1.621898	171	MCOLN1 TSPAN4 CYP27A1 DPYSL2 FIG4 MSRA CD1C FUCA1 GAS6 EOGT IGSF6 TRIB1 PILRA PLA2G7 SH2B3 MAN2B1 ASAP1 LMNA RNASE1 HLX LAIR1 SIRPA SLC19A1 TUBB6 CST3 EPB41L2 ZMIZ1 YBX3 CPVL GAA SOCS2 CD302 HLA-DQA1 SIAH1 HCK NINJ1 SLCO2B1 VAT1 IFNGR1 CSTA SNX2 CD83 TNFRSF9 RASSF2 PLCG2 TNFSF13 TCF4 MILR1 CD86 ATP6V0C CD81 BMP2K MS4A4A DAPK1 LIMCH1 MAFK MMD CREG1 EHD4	down	**
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN	0.0001932	0.0017148	0.5188481	-0.3092669	-1.621377	171	NLRC4 KMO TMEM52B CYP27A1 TMEM170B FYN CCDC88A NEDD4L DNAJB14 ASAH1 PBX3 CAMTA1 ADIPOR1 SLAIN2 PPP3CA MPHOSPH6 TCF7L2 TAPT1 AGO3 THBS1 PDE8A NR1D2 PINK1 FAM76B CNOT6L CDKN2AIP HAUS1 CDC40 RAB8B C2CD2 DESI2 MED30 UBAC2 PTGER2 SNX1 PRKACA TRAK2 ZBED5 GAS2L3 ECI2 ATG2B CD81 SERINC3 CCNH INTS6 CPQ CEP170 TRAPPC8 MEGF9 MEX3C CEPT1 NFU1 SPATA5L1 SPOPL CHML SLC19A2 MAPK1 MZT1	down	**
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP	0.0007253	0.0051810	0.4772708	0.3613445	1.620629	168	HABP2 BUB1B NUP107 TIMELESS TRAIP PMS2P5 SAYSD1 DNAH3 DPYSL4 ORC1 DTL LIME1 MRPS35 CHAF1A KCNMB3 SETDB1 RAD54L SALL2 WDR60 SLC9A3R1 DET1 ANAPC5 TNFRSF25 AAGAB EZH2 ETFB CCDC57 PA2G4 ZNF606 DCLRE1C TAPBPL DHX40 ADAM28 MC1R ARHGAP32 SLC37A4 SCN8A MGMT ACAD10 DAP3 ENOSF1 CDK13 CNDP2 CCT7 PPP1R8 MCM6 ZNF248 TRANK1 MCM5 HMCES EDAR C1QTNF3 ALOX12P2 MSH2 TM7SF3 TUBGCP4 CDK5RAP1 ABHD10 TRAPPC9 MICU1 SNRNP200 CELSR2	up	**
GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN	0.0002446	0.0020871	0.4984931	-0.3089556	-1.619994	166	CD55 LMO2 SAMHD1 MYADM CITED2 GGA2 PDE2A B3GNT5 PICALM KLF6 LCP1 PPP3CA FLI1 AHNAK FOXO1 RRM2B ID3 VIM SELL LBH ADD1 LMBRD1 AFF3 NCOA1 EMP3 FRY WASF2 SGK1 STAT4 SH3BP5 SNX29 MAP4K4 JAK1 SNX2 GMFG PXK SNX9 KLF2 BIN2 TGFB1 CC2D2B TEC LGALS3 CCR6 CXCR4 LRP12 TBC1D1 BRWD1 RNF38 CCND3 IQGAP1 GIMAP4 IRF2 ARHGEF18 ATP6V0A1 EGR1 CTSH TUBA1A ATP1B1 CSNK1G3 CD69 RAD21 TRIM25 SH3BP2 TNFRSF13C FCHSD2	down	**
GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP	0.0001676	0.0015348	0.5188481	-0.3046247	-1.618101	177	WTIP ARHGAP31 SWAP70 ADCY4 HSD17B11 EMCN LY86 INPP5K CALCRL ELMO1 FAM49A TXNIP TMEM204 MAP3K8 GATA3 PPP1R13B KANK2 TFEC HERC3 MTHFR CD37 TIPARP EFCAB14 FUT7 ITIH5 PDE8A CCL4 TLR4 PNRC1 RECK TM6SF1 WFS1 UBASH3B NCKAP1L MYLIP FMNL2 CHDH RGS18 MITF STAT4 OSBPL9 IRF8 DOCK8 RNF24 CDK14 RRAS	down	**
GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP	0.0002799	0.0023152	0.4984931	0.3609876	1.618062	170	CEP72 MCM10 POLQ PBK PRIM2 GINS1 CDK4 AURKB SFXN1 CCNB2 UMPS SHMT2 RANBP1 NUDT1 CISD1 AURKA EME1 POLD2 MCM7 RRM2 SMYD2 CCDC58 ORC6 FBL SPC24 DSCC1 CAD RAD18 PPIL1 CKS1B ASF1B CDK1 POLE2 UCK2 BIRC5 GMNN ADAP1 MECR NF1 PSMC4 CENPP POLL TK1 MFSD2A GEMIN5 AGPAT5 PRMT7 POLD1 POLB CLTB GEMIN6 FAM136A SNRPD1 LSM7 PRIM1 BANF1 RFC5 RAD51 SEC13 ZMYND19	up	**
GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	0.0001167	0.0011086	0.5384341	-0.3061764	-1.617344	174	WEE1 ARHGAP31 PTP4A2 FYN PDE1B KIAA1109 CORO1C FLVCR2 NR3C1 TGFBR3 GGA2 TMX4 ASAP1 PTPRM CD5 C1orf21 PICALM CAMTA1 RB1 CD58 EFCAB14 AGO4 KIF1C DENND3 COTL1 EPS15 ALOX5AP PPP2R5C SLC6A6 CRIM1 MYO1C PHACTR2 CPEB4 GTDC1 TNFRSF9 CCR4 SAV1 BAZ2B ATXN1 SYT11 MGAT2 NLRP3 GLUL CCDC92 ABI3 AIM2 KIF1B IQGAP1 LPAR6 PIEZO1 SLFN11 KLRF1 SPSB1 UBR2 ZBTB16 CCDC112 AOAH KIAA2026 FAM53B RCBTB2 ATP2B4 KATNAL1 USP45 CFLAR AKAP13 FAM89B BMPR1A MYO5A GALM	down	**
GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN	0.0001708	0.0015581	0.5188481	-0.3044410	-1.617125	177	CD300LF IL1A SOWAHC F2RL3 LYVE1 HCAR2 BACH1 MYD88 FGR NDUFAF1 PLXNA2 ITGA5 HDC SERPINB9 TOR1AIP1 AKT3 TXN TUBB6 TIPARP IL10 MEFV BST1 THBS1 SOCS2 CLIC4 CDKN1A SELL CCL4 CCND2 MAFF PROCR ETF1 IL6 DDHD1 PNO1 SOCS3 JUNB ATP11A RHOJ IRF8 OGFRL1 CST7 TMEM192 FOS STXBP3 FPR2 BRI3 ADPGK IL18 ADAMTS4 RIPK2 TMEM184B FNBP4	down	**
GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP	0.0002799	0.0023152	0.4984931	0.3604419	1.615616	170	CUZD1 TICRR JPH3 PSPH KIF18B TTK CDCA2 GTSE1 KIF14 STIL IGSF11 CCNF CCT6A WDR62 NDUFB8 EXO1 KIF23 BUB1 AUNIP MCM7 ZNF146 MRPL27 PASK FANCD2 CHAF1B SPC24 BRIP1 IDH2 HDGF CENPJ UCK2 SPAG5 RAB11FIP4 DIAPH3 PA2G4 CCNE1 TSPAN17 ST14 NMRAL1 MBD4 HIRA CLTA SAP30	up	**
GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP	0.0002509	0.0021261	0.4984931	-0.3075839	-1.614863	167	DNAH17 SEMA6A INSIG1 ST3GAL6 CORO1C RPL23AP53 NR3C1 IL1RN IER2 LRRFIP2 SH2B3 CHMP1B ANXA5 EIF4E BTG3 UBE2D3 ZNF365 MAP2K3 MOAP1 SRSF5 DNTTIP2 RABGGTB TOPORS PRKRA DCP1A FLT1 IL6 SOCS3 NXF1 GABPA ELP5 JUNB CSTA PPP1R15A FBXO11 HUNK DLEU2 TSPYL1 GPRC5A AGFG1 SLC3A2 AZI2 USP7 MAPK8 TFEB OSGIN1 PIK3C3 ZNF143 TAB2 G3BP2 RBM48 SKI TMEM87A AIM2 ITCH SFPQ MED17 PPP1CB	down	**
GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN	0.0003615	0.0028965	0.4984931	-0.3081996	-1.613974	157	ABHD5 SLC12A6 PLEKHF2 SLC25A30 PPM1D TXNIP BTG2 RANBP9 PARVG ABCG1 CLK1 ITSN2 TFRC CCNI TLE4 CDKN1A ATF3 ARHGAP9 CLK4 N4BP2L1 CLIP4 C16orf54 BTG1 AXDND1 PPIL4 SLC25A25 PHTF2 UTRN HCST DOCK8 ZNF597 MEAF6 RHOQ CDK17 ZFAND6 DUSP5 ZBTB11 C16orf72 DOK2 ADAM10 HELZ JUND TRAC PIP4K2A ESYT1 MEGF9 MEX3C CREBBP RNF38 FOXJ2 SKI LYST MMD	down	**
GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP	0.0002604	0.0021949	0.4984931	-0.3072671	-1.613200	167	CXCL3 SCN4A SECISBP2L CD55 PTPRE ELF2 DNASE1L3 ZEB2 SH2B3 UBL3 EIF1 SERINC1 ABCG1 GLS HLX TRAF6 SPTBN1 CLK1 GPM6A FLI1 PTPN12 MTMR6 SRSF5 YBX3 KLF7 DOCK9 CXCL2 CTBS SMAD7 ADIPOR2 CRIM1 HCK RPS6KA2 MOB4 MYO1C PSEN1 NEK7 ZNF548 MAGI2 APBB2 STX7 ENPP4 RPS6KA1 AGFG1 BAZ2B VAMP4 MIA3 SLC24A1 HBP1 SBSPON N4BP2L2 CEBPD CREBBP DAPK1 RASSF8 LYST DNAJB9 CYTH1 IL16 RNF13 EVI5 ABI1 SH3GLB1 RB1CC1 FAM8A1 ZFP36	down	**
GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN	0.0001478	0.0013772	0.5188481	-0.3039072	-1.612835	176	SLC31A2 SIDT2 TUBD1 SGK3 ADPRH CLEC12A TXNL1 NEDD9 MTF1 ZNF410 ABHD6 CRK TCF7L2 SETD3 CD58 GMEB1 CASP1 RNFT1 VRK2 DPH3 CYP20A1 TLR4 ZMPSTE24 SMNDC1 FMNL2 DDX60L CRNKL1 DESI2 PI4K2B NAA30 ZCCHC9 BLOC1S6 GRSF1 SIGLEC1 CD164 AZI2 MSMO1 ZCCHC10 IFNAR1 THAP9 CCR1 PHF11 ACYP2 POLK ME2 BMP2K SLC31A1 NT5C2 METTL21A CYP2U1 HAVCR2 TMX2 CTSC FNIP2 HEBP1 CNOT8 SCLT1 PPP2R3C DUSP6 ZNF106 SNW1 IFIT5 LAMP3 SNX14 UNC50 C11orf54 BCL10 NMI CCNYL1 NTAN1	down	**
GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN	0.0002131	0.0018669	0.5188481	-0.3079683	-1.612298	162	GIMAP8 LRRFIP1 SLC6A12 CDH13 MEF2A ALAS1 FRAT1 NFATC3 SCARF1 STARD4 TACC1 ENTPD1 PARVG TCF7L2 EVI2B VAMP5 HLA-DQA1 MAFF ZDHHC20 CLN8 MYO1C DDHD1 OASL UTRN MITF GSTO1 PCGF5 MALT1 DOCK8 BLOC1S6 LMCD1 ICAM2 AKIRIN2 TGFB1I1 ATP6V1A CBFA2T3 ATP6V0C HBP1 DECR1 KAT2B CLEC2B TAGLN MBNL1 CCL20 SELPLG CCDC69 BLOC1S2 SCPEP1 RAD9B CTSC EDN1 LPAR6 ATP6V0A1 CSF2RB SPPL2A CLEC4E ITGAL SLC38A2 FAR1 DNAJB4 ANKHD1 NMI ZBTB46	down	**
GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP	0.0002131	0.0018669	0.5188481	-0.3079614	-1.612261	162	PRMT8 TMEM100 ABHD5 P2RY1 BACH1 SPATA1 HPS5 RCHY1 PDE2A APOD RRAGC HBEGF ABCG2 LAMTOR3 TIPARP ZMIZ1 IL10 CSRNP1 TLE4 KLF9 ZFAND5 SCAF4 TANC1 CLN8 PRCP GZF1 BCAR3 CABLES1 SH3BP5 CPEB4 ST6GALNAC4 RABGAP1 VPS26A OSM ATP13A3 GPRC5A GAS2L3 SMCR8 ZFYVE9 FEM1B ANKRD12 N4BP2L2 ABL2 CEP170 THAP6 SLC2A9 BCAM OSER1 STAM2 RAD9B JMJD1C MAFK FNIP2 SNX15 ZFAND2A SPHK1 RABGEF1 NAF1 ACVR1C	down	**
GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP	0.0005010	0.0037960	0.4772708	0.3592003	1.612032	172	TFPI2 SCIN TICRR CCDC34 MPP6 NDC80 DEPDC1 GINS1 CDCA2 IQGAP3 PTTG1 CDC6 ARHGAP33 DTL CCT2 NME1 WDR62 C9orf116 RND2 MCM7 RAD54L KIF11 POLR3C THYN1 CKAP2L RAD51AP1 SPC24 PKMYT1 PSRC1 KNSTRN CKS1B NCAPG2 CDKN2C CENPH SCTR SEC61G PEG10 SPAG5 CENPP CCNE1 DLGAP5 CHTF18 ESCO2 GAS2	up	**
GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN	0.0002478	0.0021066	0.4984931	0.3586019	1.611569	176	HMGA2 CCDC162P CDC45 CCDC127 THOC3 NDUFS6 GPI MCM8 ZFYVE19 COQ3 DCTN2 TAMM41 MRPL15 EME1 CBX3 POLD2 RAB19 CDC25C ABCB6 CKAP2L TIMM50 CMAS POLR3K ACTR3B OCIAD2 KCTD1 VIPAS39 GNPAT SCLY MRPL11 TRIM37 DTYMK C1orf131 DAP3 LIN37 TEKT3 CENPM STOML2 ZCCHC17 FAF1 CKAP2 TDP1 SNRPD1 MALSU1 EIF3D EIF3K SHCBP1 PRPF31 HOOK2 MRPL9 NDUFS8 WDR76 NMT1 NUP93 PPP1R14B VNN1 MAP2K2 ACSL5 TRAPPC6A TIPRL DRG1 PLK4 DFFB LCMT1 TOMM40 KIAA1841 MCEE HSD17B7 TLCD1	up	**
GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN	0.0001740	0.0015755	0.5188481	-0.3032862	-1.610991	177	CXCL3 SCN4A MS4A7 TBX3 LPXN LY86 FUT1 MYD88 PRPF38A GNPTAB ZBTB2 PDCL ARHGAP10 RRAGC COX18 KLF6 SERPINB9 TIPARP IL10 MPEG1 ITM2B C9orf72 CCND2 WFS1 SLC6A6 KBTBD4 IL7R SPRYD7 SMNDC1 CMTM6 HCK PROCR USP25 PKIG SGK1 STAT4 SH3BP5 ATP11A PRKCE GRASP MORC3 OGFRL1 CDK14 TMEM128 SPOP EPHA3 STXBP3 NR2C1 CD86 GNB4 RNF2 TAB2 NSUN4 FNBP4 TIMP3 KLRK1 CYTH1 SMAD4 IRF2 AFTPH SPSB1 KLF15	down	**
GSE2585_CD80_HIGH_VS_LOW_MTEC_UP	0.0007726	0.0054790	0.4772708	0.3700907	1.610736	132	COL17A1 SHISA3 ZNF12 CIB2 COL27A1 GCNT3 THEM5 IRS1 ABCA12 BCAS1 ENAM LAMP5 SLC6A3 CYP27B1 ASPHD2 CCDC150 SDR16C5 ANO9 RND2 TSGA10 FLG TOM1L1 DCDC2 ASB16 PROB1 NRG4 DLG5 FAT1 SCTR TMEM182 POLR1C C9orf43 LAPTM4B ILF2 ASGR2 OS9 PCDH9	up	**
GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN	0.0004722	0.0036301	0.4984931	0.3585922	1.609428	174	EGLN3 ELOVL6 CENPF PHGDH TTK CDCA2 AP1S1 PTTG1 GPI ACOT8 CCNB2 STC2 MCM4 SPPL2B RUVBL2 CISD1 RND2 KNTC1 FANCA MSX1 CLSPN RAD54L CMBL PYCR2 CKAP2L CBY1 DCTPP1 MTG1 UQCR11 THOP1 KCNE3 TTLL9 UNG CMTR1 DNA2 FAM98C SAPCD2 AARSD1 MRPL52 ESCO2 IGHM LRWD1 PRMT7 COX10 TIMM13 MCM5 CAPRIN2 NDUFS7 HAUS4 NEFH LHPP CBR1 B9D1 MSH2 DCPS CCDC88B UQCRQ CLEC11A PNKP CENPE MPG UBE2C C12orf10 TEX9 COPE OVGP1 MAN2C1 RAB40C SIGIRR PPARGC1B RPL36 PSMB10 MRPL2 LZTS2	up	**
GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_UP	0.0002642	0.0022192	0.4984931	0.3575937	1.609130	179	SAA1 CDH17 PHGDH ECE2 METTL1 ALDH18A1 CDC6 CDC25A ACY1 CCT6A MCM8 SHMT2 EXO1 C19orf48 IDO1 WDR3 CCDC58 AIMP2 C7orf50 DNAH11 ALG3 DDX56 MRPL37 HDGF EXOSC2 DTD1 CCT3 ATIC UNG MRPS2 ATAD3A NOP2 DDT FAH YDJC C12orf45 DBN1 ZNF239 MFSD2A DNAJC11 MAGOHB AHCYL1 GPATCH4 PRMT1 BSN TMEM147 SURF2 CLUH DUS4L POLR2I POLR3E SF3A2 TSR1 PRMT5 USP39 WDR77 HK2 POLR1B MRPS27 MUC1 FTSJ3 PCGF6 CLNS1A MRTO4 WDR55 MED22 SFXN2 SHQ1 SRM PARL ADSL APRT SNHG17 TIMM10 SAMD11 MRPS6 RBM8A TIMM9 EBNA1BP2 COQ4 CTPS1 EEF1D EXOSC7 DNAJC2 GRWD1 NUP43 RRP1B IDH3A CHCHD4 PUS7L HTR7 AEN PECR PLSCR1 GART PSME3	up	**
GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN	0.0002751	0.0022914	0.4984931	0.3570507	1.606686	179	RIBC2 GMDS BDH1 TIMELESS KIF14 TTC26 PLK1 CENPA TYMS ACY1 SPDL1 AGK KIF23 KIF15 TOP2A RRM2 RAD54L MRPL3 CDC25C KDELR2 ORC6 EHHADH DCTPP1 ETFA BLM CKS1B EFCAB11 NCAPG2 CDK1 UNG PSMB5 OARD1 SNRPE RTCB PA2G4 RNASEH2A VBP1 UQCRFS1 TACC3 MRPL11 HIRA GINS2 KIF20B LAMTOR2 PRMT7 POLD1 MARCKSL1 AAMP MRPS33 MCM5 TDP1 PDIA4 LSM4 U2AF2 CCNA2 ADM PRIM1 PRDM10 CDC42BPA ECHS1 GTF3C5 NME7 ETHE1 PFDN4 TP53	up	**
GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP	0.0008841	0.0060755	0.4772708	0.3620062	1.606640	159	SAA2 KIF20A ADH1C LAD1 CEP89 MCM10 BDH1 PSPH SCN3A COLQ SFXN1 FIGNL1 ANKRD22 RBBP8 SMPDL3A EIF3B MYL6B NUB1 CASP2 HMMR COPG2 CEL RAD54L KIF11 SIDT1 KHK SLC45A3 EDN2 BTBD2 CDKN2C CDK1 ZMIZ2 OAT NEIL3 OARD1 TRAF5 TCTE1 MNS1 ARL6IP4 FBXO4 MRPL4 SND1 COPS6 CHTF8 SLC41A3 CATSPER1 MRPL14 HLCS RDH10 NDUFA8 NDUFS8 AGBL5 UBAP2L	up	**
GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_DN	0.0002951	0.0024287	0.4984931	-0.3059702	-1.606391	167	HMOX1 CLDND1 BACH1 ST3GAL6 NEDD4L CITED2 CYB5R3 NR3C1 ZBTB2 ITGA5 MAP3K8 IFI30 ANPEP RNASE1 STOM SRGN TCAP TIPARP ZFAND5 UBQLN1 RBMS1 P2RY2 CCL4 SFTPD PIK3C2A MATN2 GNAQ AFF1 RSRC2 IL17D JUN ST6GALNAC4 JUNB PTGER4 PCGF5 UNC13B SNRK AGFG1 CD164 TGFB1 EHD1 TEC NAB1 CD86 PIM1 BAG6 CCR1 ETS2 CEBPD SOAT1 HNRNPC LYST MCOLN2 TNFSF9 RHOT1 RNH1	down	**
GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN	0.0006896	0.0049550	0.4772708	-0.3229486	-1.606365	123	TRHDE KCNA2 GIMAP8 INSIG1 GPC5 TMEM170B SH2D3C GFOD1 FOSL1 NEDD9 AGPAT4 TTL FAM89A TMEM74B PRSS12 RHOB FABP5 CFD ITPRIP PLAUR ID3 KLF11 DRAM1 SPAG9 DUSP1 CPT1A GPR157 MAFF NINJ1 IL6 VPS37A MN1 RBKS ISM1 SH3RF3 DUSP5 PDCD1 C8orf37 GEM MRPL1 NLRP3 ST6GAL2 B3GNT2 GCNT7 ZFPM2	down	**
GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN	0.0005730	0.0042363	0.4772708	0.3576721	1.605174	172	CEP72 BDH1 CCDC34 SORD NIPSNAP1 TRIB3 RBBP8 UHRF1 CDC25A APOL2 SHMT2 DCTN2 CISD1 STAP2 MCM7 PKM ORC6 KHK IDH2 NSF MRPL37 POLE2 DTD1 GMNN UNG MRPL17 KIF2A LRRC42 SF3B3 MAD2L2 RECQL4 UNC45A POLR2H VBP1 MOV10 GALK2 PSMA5 SNRPA LMNB2 TUBA3D MRPL52 TMEM237 MAGOHB RAB24 ANKRD6 FAF1 FBXO22 TMUB1 PIGX GLO1 LRP11 CCNA2 RFC5 GBP2 PAXIP1 FRMD6 GPX7 NAT10 WIPI1 CORO1B PRKAG1 TFB1M	up	**
GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN	0.0002614	0.0021998	0.4984931	-0.3060370	-1.604443	171	CXCL3 IL1A SOWAHC ARRDC4 MOB1B EDEM1 RBM7 MALAT1 CYB5A PARVG CAV2 STOM SLAIN2 TNS1 ITSN2 ARRB1 MTMR6 PPT1 ZADH2 TMED5 FBXL3 NFKB1 MARVELD1 GCA N4BP2L1 MPC1 RUFY3 MEDAG GLB1 SPIN1 ELF1 PHTF2 PHACTR2 MTMR14 SH3BP5 ENPP4 HERC1 MSANTD2 HOMER1 DEDD CELF2 TCF4 CNOT7 HINT3 GTF2B GEM PDLIM5 NBN B3GALNT1 RIPK2 TMEM184B FNBP4 STK4 CYTH1 ITCH CBX7 MRPS28 SERPINE1 CLIP1 ENDOD1 DYNC1I2 CHAC2 MPV17 RCSD1 IRF1 TRIM25 CCPG1 CASP3 ANKRD44 IVNS1ABP ZC3H7A CAAP1 SPAG7 HBS1L IL10RA	down	**
GSE20715_0H_VS_48H_OZONE_LUNG_UP	0.0002341	0.0020044	0.5188481	-0.3074132	-1.604003	168	CD52 PDLIM2 PTPRE FIG4 LYL1 LY86 LMO2 INPP5K NEDD4L PLEKHA1 YPEL5 SLCO2A1 TLCD2 SLC44A2 CLEC14A ACOT2 SRGN CD37 FBXO8 EVI2B SRSF5 PTPRO PTPRC SLC6A6 SEC31A ARHGDIB ACTR2 RPS6KA2 MYLIP MYO1C HMBOX1 RAB31 SNX2 DAPK2 IRF8 EHD2 GIMAP1 SORT1 ZNF521 SERPINB1 IFNAR1 CD81 DECR1 RGS2 PCCA ELF5 ARAP2 SESN1 CXCR4 PTCH1 CD19 LIMCH1 EMC3 GIMAP4 CNN2 CNR2 FKBP1B PXMP4	down	**
GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN	0.0001995	0.0017641	0.5188481	-0.3018943	-1.603598	177	ACP5 SIDT2 USP12 TMEM126A C18orf32 SNX10 GIMAP8 PTPRE LIPA TMOD3 SAMHD1 BACH1 CALCRL SYS1 CYB5A LAMTOR3 ZYG11B ATP10A EVI2B PRKD3 SELL DUSP11 LBH CLK4 SMAD7 UNC5A AKIRIN1 LMBRD1 RSRC2 SLC25A33 S1PR4 SNAP23 RHOBTB2 KCTD12 TYROBP OSTM1 UBAC2 GMFG GRB2 RC3H1 RPS6KA1 YWHAZ SNRK PLCG2 CD164 SRSF6 HBP1 ACADL MFNG IL18RAP SEC63 TRAPPC8 ESYT1 TAB2 GIMAP4 EHD3 FEZ2 IRF2 YTHDC1 EGR1	down	**
GSE14415_INDUCED_VS_NATURAL_TREG_UP	0.0006820	0.0049226	0.4772708	-0.3145051	-1.603573	138	CD55 CALCRL CIR1 NR3C1 ZBTB2 ZEB2 LATS2 EIF1 C1orf21 SWT1 RGCC ADRB2 CLK1 FOXC2 NRARP CASP1 COQ10B NKIRAS1 CCL4 DUSP1 DNTTIP2 N4BP2L1 TBC1D4 MRVI1 ZDHHC20 TMEM9B AREG VPS37A CREM NDNF JUNB EPC1 TBC1D12 CD7 EPC2 KLF2 FOXO3 KLRC2 ADPRM CHPT1 ZRANB1 BAZ2B RNF2 GEM YAF2 CDC42EP3 POLR2M ULK2 CD3G DNAJB9	down	**
GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN	0.0004297	0.0033498	0.4984931	-0.3044791	-1.602507	169	LRRC8C GPR65 MIR22HG EGR2 FLVCR2 SLC15A3 LAMP1 IER2 AVPI1 GM2A EMILIN2 TMEM74B SERPINB9 SRGN BTG3 TIPARP CSRNP1 SYNPO LEPROTL1 GAA STX3 ATF3 JAM2 ARC PLEK SH2D2A UBASH3B DEGS1 CMTM6 ST6GALNAC6 RPS6KA2 RBPJ RAB8B HIC1 ATP6V0B PLK3 PPP1R15A PTGER4 EEA1 MALT1 CRYM TSSK6 PREX2 TBX21 RGS13 CLN3 CST7 AGFG1 SLC3A2 ATP6V0D1 TGFB1 SERPINB1 ATP6V0C TAGAP BRI3 CLCN6 CCR6	down	**
GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN	0.0002264	0.0019521	0.5188481	-0.3021439	-1.602175	181	DNAH17 SIDT2 LPIN2 SGK3 PECAM1 INPP5K DDX6 MKNK1 NR3C1 CBL PDE2A UBL3 EIF1 CSGALNACT2 NFE2L2 SPTBN1 MCL1 CD37 CCNI SRSF5 RNFT1 MAFG KLF7 HPSE PLEKHB2 GNAQ RPL17 RYBP NEK7 NXF1 VAT1 KCTD12 RAPGEF1 CCR7 IRF8 COBLL1 STX5 SRSF6 ING3 ZFAND6 GSAP DUSP5 FCGRT TOB1 JUND LAT TRAPPC8 FBXO30 ING2 CEPT1 ABI3 CYTH1 IQGAP1	down	**
GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN	0.0001705	0.0015581	0.5188481	-0.3013792	-1.601127	179	LIPA LRRFIP1 THBD SIK1 KIAA1109 MEF2A IL1RN OTUD4 PFDN1 ANXA1 COQ7 MAP3K8 HSPB1 KLF10 PPP2R2A RB1 NDEL1 CD58 CASP5 TMED5 STX3 VRK2 VIM ZBTB43 DUSP1 N4BP1 FKBP15 TDRD7 PROCR PDHX ELF1 NSMAF DCTN6 OASL TMEM251 PPP1R15A CGGBP1 GRSF1 AGPS CD164 PTP4A1 NUP153 BCAS2 GSAP TGIF1 TOB1 DECR1 GPR18 PGGT1B CGRRF1 NT5C2 SP100 ISCU MAP3K4 CTSC DOCK10 CREG1 IRF2 SETX PHYH	down	**
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN	0.0005002	0.0037956	0.4772708	-0.3058311	-1.599861	158	USP12 KLF13 EMP2 CLDND1 NXPH3 CAV1 TSHZ1 IL23A CLCF1 FBXO7 CACNA2D2 LUZP1 TTYH2 NR4A1 IL18R1 ARHGEF2 PDE4D RHOB ZMIZ1 SYNPO PIP5K1B SLC12A4 MVB12B ZADH2 SSH1 MATN2 DSTN HES1 ST6GALNAC6 PDK4 CREM KIF13A IFRD1 UBAC2 PRKCE GRASP FSTL3 TPRA1 PKIA TGIF1 CD86 RGS2 PDE4B CXCR4 TMOD2 ALDH2 AMZ2P1 CYTH1 PAIP2	down	**
GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_DN	0.0038735	0.0196578	0.4317077	0.3903208	1.598293	86	RIBC2 SLC5A5 SPATA24 PPP1R1B PAX9 DCST1 MIR205HG CHST4 MKS1 PCLO CMYA5 TMEM132D C2orf81 SLC34A3 PCDHGB7 WDR72 C11orf16 SMYD5 EGFR LINC00265 AFAP1L2 KRT18	up	*
GSE17721_CTRL_VS_CPG_4H_BMDC_DN	0.0005057	0.0038091	0.4772708	-0.3048448	-1.598163	163	SNX10 PTPRE CLDND1 TXNL1 CDH13 MYD88 PRPF38A DSCAML1 IL1RN IL23A CCNL1 GINM1 TNFRSF8 RAB33B FOXP1 BFAR CLN5 SFRP1 TXN PIP5K1B RNFT1 OSTF1 NFKB1 ATF3 DUSP11 RUFY3 AFF1 TANC1 PI4K2A TDRD7 RPS6KA2 MTMR14 ADRA1A APBB2 GYPC GRB2 CST7 POGLUT1 PIK3AP1 HNRNPD STXBP3 SOD2 PLAA PDE4B IL18 SERTAD1 IER5 TAB2 G3BP2 KATNA1 ZDHHC5 SAMSN1 LDLR SLC22A3 MACROD2	down	**
GSE42724_NAIVE_VS_MEMORY_BCELL_DN	0.0005057	0.0038091	0.4772708	-0.3045829	-1.596790	163	PEBP4 EDNRB SGK3 USP12 SNX10 FYN KIAA1109 MSRA CCNL1 ANXA1 GLS HLX BFAR PPP2R2A PPM1K GCHFR PRKD3 DRAM1 CLIC4 SEC24B MGAT4A RBMS1 FRMD4A KLRD1 PINK1 PPP2R5A N4BP1 AFF1 NRBF2 LRCH1 HMBOX1 CPEB4 GLUD1 RCAN1 CD83 YWHAZ NUP153 SAV1 PIM1 GPR84 HINT3 STX12 CLASP2 PGGT1B PDE4B IST1 SETDB2 TPT1 PIP4K2A RIPK2 SREBF2 KATNA1 LDLR SPSB1 RBMXL1 C1QB ZYX FAR1 PPIP5K2 CD69	down	**
GSE3039_B2_VS_B1_BCELL_DN	0.0010981	0.0072989	0.4550599	0.3597756	1.596740	159	SCIN CEP89 TICRR BUB1B CCDC127 ECE2 METTL1 IQGAP3 POLE BAMBI CDCA8 GPI COQ3 RANBP1 RSPH1 IGF2BP2 HOMER3 KIF2C MAD1L1 CLSPN ICA1 AKAP1 RAD54L ANKRD13B CHEK1 DCTPP1 SPC24 TST CNOT3 ALDOA PSRC1 ASF1B GOT2 SLC16A13 HMGXB3 RAPGEF5 ILF2 CCNE1 SCLY SNRPA C19orf12 TMEM237 KCNC3 MLEC CENPM CENPT CLUH SLC1A5 SH3PXD2B CKAP4 PPP6R2 CPT1C SMPD4 TP53 FRMD6 APEX1 NOMO1 E2F7 NDUFB7	up	**
GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP	0.0004550	0.0035246	0.4984931	0.3551329	1.596147	178	PPM1H MDM1 BDH1 PAGR1 NPY6R HILPDA ECT2 COX11 MPPED2 ZNF74 HLTF HOMER3 MCM7 ABCC5 PASK CHAF1B RNFT2 TRMT61B CBY1 KHK C2CD3 TRPV4 GOLGA8A VPS72 STK11 POLR2H SNRNP25 NFS1 ATP6V0E2 LRRC8D JTB OLFML2B GALNT7 TNK1 DGKA RPA1 MCM6 MCM5 TBC1D16 LRIG1 KATNB1 CREB3L2 POLR3E PRKD2 NT5DC2 UNC119B SPSB3 MSH2 GTF3C2 RFC5 USP39 NDUFA8 CDK5 SYNRG SEPHS1 FGFBP1 PPP2R5D ZER1 PARP2 ESM1 RCN2 SHQ1 PCNT PARL RWDD2B TMPO NCKIPSD STXBP1 PCBP4 HDAC3 MIEF1 NINJ2 TTC3 GRAMD4 HMBS NSUN5P1	up	**
GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN	0.0013918	0.0087833	0.4550599	0.3620852	1.596018	148	TICRR NUP107 NEK2 SRGAP3 SORD CDCA7 DGCR8 NUF2 EXOC3 MCM2 CDC25A PRC1 XDH DTL COPB2 ITGA2 MELK SDHA TOP2A KIF2C MPHOSPH9 GPSM2 MCM3 CHAF1B MAD2L1 AKT2 IPO9 NCAPG2 CBX5 RFWD3 PSAT1 NUP205 DNMT1 CCNE1 DLGAP5 TACC3 TRIM37 SSRP1 GALNT7 KIAA0100 MAN2A1 FBXO22 MCM6 WDR35 LANCL2 GINS3 LRRK1 MSH4 VDAC1 ANAPC2 VDAC3 PRPF3 SEPHS1 BPNT1 SF3B2 RCBTB1	up	**
GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP	0.0001356	0.0012705	0.5188481	-0.3011986	-1.595695	186	LPIN2 PNPLA6 GLIPR2 SPN ADCY9 RDX FYN PPP4R1 CCRL2 FLVCR2 IDI1 NR3C1 NEDD9 ARHGAP10 SH2B3 PTPRM C1orf21 TNIP3 ANXA5 SPIRE1 GATA3 PPP3CA AHNAK OSTF1 RMDN3 SIK2 EPS15 MBD2 PPP2R5C SH2D2A SLC6A6 PI4K2A PHACTR2 PRKCE IDS GTDC1 GFPT2 TIGIT RUNX3 NKG7 PEA15 ATXN1 GABARAPL1 STK40 PHF2 PDE4B RXRA ARAP2 CALHM2 SEMA4A SIK3 RBMS3 CCDC92 AIM2 NABP1 PMAIP1 PIEZO1 SLFN11 FNBP1	down	**
GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP	0.0003584	0.0028769	0.4984931	-0.3038776	-1.595404	167	RAB11FIP1 DENND5A HHEX FYN LY86 PLEKHF2 WDR74 CYB5R3 ZCCHC2 SLC15A3 BCL2A1 CD1C FRAT1 NFATC3 SH2B3 LAIR1 JAM3 GPM6A KLF4 DENND3 GRK5 SCAF4 SSH1 PER2 NFKB1 TM6SF1 TP53BP2 IL24 SNN INPP5B RNF141 PIKFYVE CD83 REL RASSF2 RUNX3 CD74 SAV1 DCK SERPINB1 MACF1 ATAD2B DIXDC1 SP100 OSER1 CD19 PAK2	down	**
GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0003967	0.0031373	0.4984931	-0.3075770	-1.595355	151	SLPI SGK3 KCNA2 TRPV2 PDE1B SAMHD1 IL1RL1 FAM49A STARD9 HBEGF RAPGEF4 ZDHHC2 SPIRE1 ANPEP STOM SLC25A37 ITSN2 MSR1 MEFV TCP11L2 FAM49B SELL ARHGAP9 FRMD4A CD300C CLEC9A PEAK1 HES1 MOB3A PRCP TMEM9B PHACTR2 HCFC2 SLC14A1 ETS1 PODXL COBLL1 CDK14 KLF2 YPEL2 SORT1 TFEB ZBTB1 CD81 KYNU CALHM2 BRWD1 SOAT1 TTC32 MBD5 TMEM109	down	**
GSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_DN	0.0014764	0.0091984	0.4550599	0.3619686	1.595076	144	TFPI2 GABRP FAM153A PTPRR PTPRH MST1L SLC7A9 DYNC1I1 GON4L INSRR CEL AGT MPO SETDB1 FHOD3 BRD9 GPR135 FUT2 ZNF512B DCLK1 FASTK HARS2 PABPN1 ITGB8 NOP2 ULK1 POLR2H ATP7B DNAJA3 MNS1 ZNF239 PRRG2 NAT9 RDH16 DUS1L WNT10B BSN MVP SPSB3 ARFGAP1 KRTAP5-9 GTF3C2 ATOX1 R3HDM4 FMOD MAU2 TIMM44 BCAT2 ARHGEF10L ZBP1 TMEM161A RANGRF KLK10 SNTA1 BRD4 BNIP1 MEN1 SAP30L DHPS KLF5 PDE1A TCHH	up	**
GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_DN	0.0004174	0.0032896	0.4984931	0.3536879	1.592789	182	FOXM1 CDC45 POLQ GMPS ESPL1 MCM4 SPINT2 EIF3B DTL MYL6B CCT2 SPDL1 MELK EXO1 MKI67 KIF15 KNTC1 CCT5 PUS7 ODF2 POLD2 COASY RBM28 RAD54L SLC35G2 KDELR2 MAD2L1 RAB13 BLM IDH2 TFCP2 EXOSC2 TNFRSF21 CCT3 POLR3K MCAT MRPL17 MRPS12 LAPTM4B CCNE1 DPP3 PSMA5 TACC3 PSME2 MRPL11 CASP7 AGPAT5 CCT7 CDC7 RAD50 SUPT16H NPRL3 LRRC59 FAM136A BCL2L1	up	**
GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	0.0001381	0.0012919	0.5188481	-0.2994686	-1.592187	180	SASH1 SOX18 LRRC8C GIMAP8 CDH5 RASAL2 AKAP7 ESAM CASP12 GIMAP6 SLCO2A1 AGPAT4 FAM49A PEAR1 ERG ARHGAP29 LUZP1 ABCG1 KANK2 TCF7L2 CYP4V2 GPR4 CSRNP1 PRKD3 MPL ITIH5 AXL CCL4 CCND2 PPP2R5C AFF3 PROCR CREBRF FRY RNF149 PHTF2 UTRN SH3BP5 EPC1 APBB2 GRASP COBLL1 CLN3 FOXO3 ZFAND6 GIMAP1 TCF4 NR2C1 TSC22D1 TSPAN14 DOK2 SESN1 GIMAP5 TBC1D1 NHLRC3 TTC28 SPOPL FNBP1 MAP4 EXPH5 MAMDC2 PLEKHA2 CSNK1G3 PTGS1 C11orf54 IRF1 RCBTB2 TRIM25 FCHSD2 CEP68 PKD1 ARHGAP30 LRRC28 ST3GAL1 MYLK MFHAS1 ZFHX3	down	**
GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN	0.0022311	0.0126835	0.4317077	0.3664173	1.591954	130	LEMD1 HABP2 ADH1C HJURP AP3B2 PROM1 NRG2 CDCA2 AURKB MST1L ESPL1 THTPA ZNF862 GTPBP3 RRM2 PASK PYCR2 CLDN9 ACVR2B-AS1 AFAP1L2 EPHA1 NPM3 LRRC4 PEG10 ANAPC7 C22orf15 MTA3 DPH2 PINLYP JTB KIAA1549 CENPV DGKA HMGB3P22 WNT10B IGFL2 CHTF8 COL5A3 USP21 HHLA3 AGMAT ZNF93 TYSND1 LINC00240 RELL2 TCF3 FGFBP1 SLC35G1 TMEM201 APOBEC4 PDK2 MST1 HUWE1 AP2B1 LTK	up	*
GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN	0.0003175	0.0025748	0.4984931	0.3528041	1.591900	184	ELOVL6 PDCD6 CCNB1 UCHL1 SLC2A1 TBRG4 BET1 RACGAP1 SFXN1 TYMS UMPS PRC1 CCT6A SHMT2 XPOT CCT2 RANBP1 KCNN4 CHAF1A MRPL15 EEF1E1 MCM7 RBM28 ERAL1 CHAF1B ACTL6A MAD2L1 ALDOA MCTP2 GMNN POLR3K DNA2 FEN1 SNRPE RTCB FOCAD RANGAP1 CCNE1 FAH DVL3 CCDC51 CCT7 CDC7 RAD50 SUPT16H LIMA1 CDC20 STOML2 PPP1R8 TMEM147 GNG4 CLUH ESRRA NT5DC2 MED27 ATOX1 BMS1 RAD51 MTHFD1 SEPHS1 CISH COX17 SART3 C12orf10 ERLIN1 CSTF1 DHDDS CXorf40A BAG2	up	**
GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP	0.0003711	0.0029593	0.4984931	-0.3031784	-1.591733	167	SLC47A1 CYP27A1 USHBP1 GREM2 SH2D3C KANK3 CRY2 CDH13 GAS6 IER2 CD36 TBX2 KCNK3 BTG2 HLX LAIR1 SLC25A37 CD93 TCAP PDGFA PER3 NPNT FUT7 STK17B CLDN5 ATG7 NR1D2 PTPRC SELL TEF CPT1A KLRD1 PEAK1 ADD1 TMEM9B MYLIP S1PR4 STAT4 IRF8 PALMD PELI1 ICAM2 NKG7 SERPINB1 ZBTB11-AS1 GABARAPL1 DOCK6 SLC2A9 PALD1 CD19 CD3G ABCA8 IL16 CEND1	down	**
GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP	0.0005530	0.0041132	0.4772708	0.3542846	1.591558	171	CEP72 SPATA24 HJURP CDC45 FANCI NEK2 SRGAP3 GTSE1 CENPA SRPK1 NCAPD2 MRPS35 SPDL1 WDR90 CASP2 DNPH1 NUDT1 KIF23 CUL7 CCDC77 SAE1 MAD1L1 MPHOSPH9 CPD WDHD1 BRD9 AHCY DCTPP1 XRCC1 BRIP1 ALDOA EFCAB11 NEIL3 ANAPC7 FEN1 DYNLL2 MTBP DAP RNASEH2A CCNE1 TRIM24 PSMA5 NMRAL1 MBD4 IQCG ANP32E CLTA RAD50 GEMIN6 PTER MAN2A1 RPUSD1 PIGU SNRPD1	up	**
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP	0.0004282	0.0033433	0.4984931	-0.3034891	-1.591331	166	CXCL3 EREG IL1A IL1B AQP9 CDH13 SLC15A3 BCL2A1 AGPAT4 IL23A SLC7A7 MTF1 TNIP3 PTX3 NDEL1 BTG3 TFRC TXN ATP6V1H PPP3CC IL10 PLAUR MYO1B NPR3 PDE8A CXCL2 CCL4 UXS1 INHBA MAFF IL24 CRIM1 SNN NINJ1 FLT1 IL6 SOCS3 ETV3 STAT4 CUL4A HRH1 PLK3 WTAP LYRM1 ATP13A3 CXCL5 ACSL1 UBB RIN2 EHD1 SERPINB1 FPR2 SOD2 ETS2 CCL20 TRAF1 PLGRKT MAP3K4 DNAJB9 MT2A FLT4 ARFGAP3 PMAIP1 MYH10 CYB5R2 YRDC HEY1 MT1E LAMP3 GPR137B SLC43A3 CFLAR PTGS2 PCID2 EBI3 DUSP2 MT1X ST3GAL1 TNFRSF1B SLAMF7	down	**
KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP	0.0002958	0.0024303	0.4984931	0.3544316	1.589919	173	CDC45 COIL PRIM2 RACGAP1 IQGAP3 E2F8 CCNB2 TYMS PRC1 XDH CIB1 SPDL1 NUDT1 MKI67 TOP2A RRM2 CDCA5 MRPL27 KIF11 LMNB1 CDC25C LIG1 PERP GNPDA1 ALDOA CKS1B CDKN2C CMAS NUSAP1 ASF1B CDK1 BIRC5 ETFB DDT DAP DLGAP5 PSMA5 TACC3 MNS1 KIF22 CASP7 CNDP2 DHRS1 TIMM13 USP18 CDC20 MRPL41 MCM5 EIF3D NFE2 ERGIC3 EIF3K DCPS BANF1 HK2 NDUFA8 RPN1 ADAM8 LXN COX17 ACSL5 NCAPH PLAC8 PRRC1 ISYNA1 NAT1 GSTT2 MRPL43 CDC34 BATF PTGR1	up	**
GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP	0.0003961	0.0031373	0.4984931	-0.3066505	-1.589752	146	GPR15 HHEX CLDND1 SLC6A12 CCDC88A DDX6 PRAM1 SUSD2 SFR1 AGPAT4 C11orf94 MALAT1 ITGA5 STOM IL18R1 REST UHRF1BP1L DENND3 MGAT4A RIT1 ARHGEF26 FCER1G TM9SF2 IL7R ARHGDIB AFF3 SENP3 CTSS SNAP23 RABGAP1 DOCK8 CD7 CELF2 ACSL1 PLCG2 CD74 ZFAND6 TEC HNRNPH3 MACF1 GPR18 ABI3BP PDE4B CCR6	down	**
GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_UP	0.0029460	0.0157206	0.4317077	0.3832463	1.586687	92	PKHD1 PRLR PTGES GRIA4 GPT FRK WDR88 LPAL2 SAYSD1 XDH MARVELD3 TRIM16L SYT12 CBLC ICA1 BLOC1S1 HHIPL1 KLHL35 HOXB5 SLC25A10 PTPN3 CAPN8 CRB2 SCTR PRR22 AKAP8L IL15RA	up	*
GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP	0.0009114	0.0062018	0.4772708	-0.3046884	-1.586281	156	ABHD5 SNX10 CD44 MYADM SYS1 FAM49A ZEB2 LRRFIP2 ANXA1 C1orf21 SERPINB9 DACH1 LAIR1 IL18R1 MPHOSPH6 SRGN BAG1 CST3 AHNAK CASP1 YBX3 COQ10B ITGAX NR1D2 HOPX CCL4 PRF1 SMNDC1 INSL6 CALM2 GABARAPL2 IFNGR1 COBLL1 TBX21 CST7 NKG7 KLRC2 SMPDL3B GSAP DUSP5 GABARAPL1 PHF11 ACADL NPTN RGS2 GEM IL18RAP ARHGAP18 GTF2F2 RORA THEMIS2 PMAIP1 CX3CR1 ITGB1 ZYX S100A8 MICAL1 SPTY2D1 UBE2N S1PR5 ATP2B4 NFIL3 ATF6	down	**
GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP	0.0004264	0.0033402	0.4984931	0.3529436	1.586141	176	ZG16B AK4 KIF18B IFI27L1 PHGDH E2F8 TRAIP NABP2 NUF2 TRIB3 RAD54B TDRKH XPO5 ZFP64 DCTN2 TNFRSF11A EMC9 COPG1 EME1 ODF2 RRM2 ERAL1 MRPL27 TOPBP1 DCTPP1 PIH1D1 PKMYT1 MRPL37 UNG RNF181 NARF NUP205 LRRC42 RECQL4 IFI27L2 RHOC DPP3 FAH CLTA GALNT3 POLD1 CENPM BCL2L1 CDK5RAP2 SNRPD1 PFKFB4 RTKN HAUS4 STK39 FARSA TM7SF3 RFC5 TPGS2 NME7 WDR76 CPOX SMC2 RPN1 ADRM1 ZBTB32 PCBD1 TUBA1C E2F7 KIF24 PRKAG1 NQO1	up	**
GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN	0.0002517	0.0021288	0.4984931	-0.2988234	-1.585855	176	CXCL3 IL1A ZC3H12C GPR65 CITED2 BCL2A1 KLF6 PAG1 NR4A1 NFE2L2 CST3 RHOB IL10 AHNAK ID3 ERP44 RBMS1 CXCL2 KCTD20 UBE2B DUSP1 PI4K2A VWF RBM39 SLC8A1 SGK1 NEK7 HMBOX1 ATP11A FOXN2 GSTO1 PTGER4 IFRD1 STX5 ATP13A3 CGGBP1 CDK14 AGFG1 GPR37L1 PELI1 DDX18 EHD1 TGIF1 FPR2 SBF2 TSC22D1 FEM1B TMEM230 BRI3 STX12 ATAD2B BMP2K RNF138 TRAF1 KPNA4 OSER1 MCOLN2 ZFAND2A SMAD4 BMI1 EGR1 ZBTB16 CLEC4E SLC38A2 NOG EFNB2 FXYD5 SNX14	down	**
GSE3982_BASOPHIL_VS_TH2_DN	0.0004739	0.0036301	0.4984931	0.3536091	1.584989	170	TP63 ELOVL6 PROM1 TTF2 TOMM34 ESPL1 SPATS2 DNAI1 HAUS5 SYTL2 AURKA RSRC1 MCCC2 ORC6 ACTL6A CAD INPP4B BLM MTG1 PHB GEMIN4 TMED3 NUSAP1 PSMB5 TMEM8B SPAG5 LRRC42 SNRPE PSMC4 FOCAD VBP1 MRPL11 LRRC8D CENPQ MRPL4 SPA17 SCNN1G SEC14L2 PFAS MED24 CKAP2 SLC41A3 MSH2 DCPS BANF1 DOHH ABCF2 HOOK2 RPUSD2 NDUFA8 SNUPN ADRM1 PFDN4 MTHFD1 TP53 APEX1 SIGMAR1 ADCK2 ENO1 WIZ CHMP6 MRTO4 PRSS50 TOP3A TOMM40 RNF8 KCNK1 TIPIN ZAP70 WNT16 E2F4	up	**
GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	0.0005820	0.0042833	0.4772708	0.3525848	1.584695	178	TFPI2 CEACAM1 RUVBL1 SORD C12orf66 CDK4 ALDH18A1 EIF3B CCT2 RANBP1 F2RL1 PUS7 WDR3 POLD2 LMNB1 AHCY DCTPP1 CAD PHB DYRK2 PPIL1 CCT3 ATIC TRAP1 NARF LARP1 PDK1 NUP205 POLR1C NOP2 TSPAN17 SULT1B1 PFAS GPATCH4 CXCL1 NOL6 UTP20 HEATR1 EXOSC5 WDYHV1 PMS1 MRPS25 RNF157 CLUAP1 APBA2 FARSB POLR1B BCL6 POLR1A DTNBP1 EIF4G1 CMTM8 TP53 SRPRB PAICS SBNO2 EPHB4 CISH SFXN4 ENO1 RRS1 MRTO4 SFXN2 SRM URB2 C3 LRP8 TSPAN3 CEP112 HNRNPAB UBE3C NUDCD1 DHPS CTPS1 GTPBP4 WDR12 GTF3A HIF1A	up	**
GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP	0.0011964	0.0078135	0.4550599	0.3537724	1.583040	166	TF KIF20A CDC45 TICRR BUB1B CENPF PBK KIF18B PKP1 CHCHD6 DEPDC1B AGFG2 ASPM NUF2 CDCA8 CDC6 CCNB2 SPATS2 PRC1 TNC LDHB HMMR EXO1 MKI67 AURKA KIF2C RRM2 CDCA5 SGPL1 KIF11 PLTP CDC25C LIG1 MAD2L1 CKAP2L SPC24 KNSTRN CDKN2C C12orf75 ASF1B KRT18 FEN1 TMEM51 OCIAD2 ADAM12 CTSV ALDH7A1 MNS1	up	**
GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP	0.0002206	0.0019090	0.5188481	-0.3002140	-1.582926	173	CXCL3 IL1A SIGLEC16 SOWAHC IL1B MIR22HG PID1 TMEM138 SLC39A8 NCF2 HPS5 RFTN1 ACER3 PPM1N ASAP1 MTF1 TNIP3 SLC7A11 BTG3 TXN CD58 PTPN12 PLAUR SOCS2 P2RY2 CXCL2 IRAK2 CCL4 FCER1G N4BP1 PIK3R5 TP53BP2 HCK PROCR SOCS3 MAML2 PLEKHA3 HRH1 HIC1 MN1 TREM1 PLK3 ELOVL7 ACKR3 PSTPIP2 FSD1L CXCL5 TNFRSF9 PXK AZIN1 GSAP FPR2 GPR84 SOD2 KYNU CCL20 ICAM1 TNFAIP8	down	**
GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN	0.0002206	0.0019090	0.5188481	-0.3001607	-1.582645	173	USP12 HVCN1 PGC RUNDC3B HSD17B11 CALCRL S1PR1 NR3C1 TGFBR2 ARHGAP29 SH2B3 BTG2 ABCG1 BFAR CLK1 ZYG11B CDADC1 FOXO1 TCP11L2 ID3 MARVELD1 NR1D2 SELL FRMD4A AFF3 SNN RPL17 BTG1 UTRN SH3BP5 RABGAP1 SKIL RC3H1 CD7 CEBPZ LETM2 FOXO3 MTMR2 ZBTB11-AS1 CLCN6 IER5 IQSEC1 SSH2 ABI3 JMJD1C ACADM SKI TLK2 CAMSAP2 SPATA5L1 ZBTB40 REEP1 SETX CDKN1B CNR2 FAM8A1 KBTBD11	down	**
GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP	0.0003818	0.0030348	0.4984931	-0.3018171	-1.582320	171	SEMA6B CD300LF CD101 SGK3 CPEB2 DPYSL2 TRPV2 LMO2 PRAM1 P2RY13 NCEH1 MAN2B1 ARSB NAAA GM2A RNF144B SPRY2 PDE4D ADAMTSL4 ARL11 PPT1 EPOR DAB2 USP2 CEBPA COTL1 AXL HPSE CD300C SMAD7 CPT1A HEXB CABLES1 CYB5R1 HPGDS RCAN1 SNX1 WDR7 TPRA1 CD34 RUNX3 XYLT1 SORT1 TSPAN14 CCR1 FCGRT RGS2 PLA2G15 GPX3 TNFAIP8 SSH2 ULK2 JMJD1C CYTH1 MMD CAMSAP2 LPAR6	down	**
GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN	0.0001730	0.0015724	0.5188481	-0.2967156	-1.582317	182	ACP5 CXCL16 SGK3 PECAM1 KLF13 GAPT PTP4A2 GIMAP8 ENG SH2D3C MYD88 FUCA1 FRAT1 TGFBR2 TACC1 C1orf162 GRN ARRB1 MPEG1 PTAFR RRM2B MGAT4A COTL1 EVI2A ELMSAN1 PINK1 PIK3R5 STK24 HCK ARL6IP5 SEC14L1 HECA LTBP2 DDX17 RHOG GRB2 RPS6KA1 RASSF2 NDST1 PPM1F RUNX3 PIK3AP1 GIMAP1 TFEB ANKRD13A MR1 GLTP CALHM2 ELOVL1 IFFO1 SIN3A DUSP7 PAIP2	down	**
GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP	0.0004594	0.0035531	0.4984931	0.3520496	1.582123	176	CEACAM1 AK4 MCM10 CHEK2 NUP107 DNAJC12 DDIT4 PHGDH TRAIP NUF2 ECT2 GPI CDC25A ALDOC ASPHD2 MIS18A SRPK1 LSM5 CCDC150 EME1 ODF2 KIF2C RRM2 WDHD1 FAM162A BRI3BP RAD18 MNAT1 SLC25A10 PTPN3 POLE2 GMNN DNA2 MRPL17 NARF PA2G4 RNASEH2A HSPA4L POLR2H FANCG TUBG1 FAH MLF2 LMNB2 TK1 GEMIN5 POLD1 SASS6 PSMB3 HNF1B RPRD1B ACLY PFKFB4 ATAD2 PRMT5 FAM3C VDAC1 RFC5 HK2 FARSB SEC13 SCOC WDR76 ADRM1 DHRS3 ZBTB32 NSUN7 NCAPD3 MSRB1 ENO1 C4orf46 TIPRL	up	**
GSE14350_TREG_VS_TEFF_UP	0.0002199	0.0019090	0.5188481	-0.2980395	-1.581891	178	SECISBP2L FYN NEDD4L GPCPD1 PLEKHA1 MTMR10 MEF2A C3orf70 TMX4 SLC44A2 ABCG2 CYB5A BTG2 ABCG1 CSGALNACT2 CLN5 CRTAM RAB14 STAT5A ITPRIP CASP1 FBXL3 NKIRAS1 TBC1D4 PIAS1 NXF1 VPS26A ATXN1L CD83 RBM22 DOCK8 SNRK CELF2 MOB1A ASTE1 CDK17 YPEL2 TMEM230 TBRG1 MAP3K2 DBNDD2 ATP9B MEGF9 SSH2 MBD5 SCAI PTEN SKI PUM1 MED17 HERPUD1 CLOCK RNF167 WDR41 CD79B MTSS1 KIDINS220 TRAT1 SLC25A45 RAB11FIP2 ZFP1 SCAF8 GALM TNFRSF1B CSTF2T PHIP	down	**
GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	0.0003713	0.0029593	0.4984931	-0.3020645	-1.581564	160	KMO ARHGAP31 CAT CLEC12A PID1 SLC6A12 SIK1 CAV1 CDC42EP2 PLEKHA1 HEG1 CD36 ADAM17 CYB5A ANPEP MS4A1 SLC7A2 MEFV LIMS1 ZADH2 KLF7 INHBA N4BP1 PIK3R5 SPRYD7 FAM102B PROCR LACC1 CD80 RNF149 STAT4 ETS1 CCDC50 NXPE3 CD83 CST7 KRTCAP2 GSAP NAB1 KCNA3 STK40 PDE4B ICAM1 WDR1 NLRP3 TRAF1 NFKBIA SAMSN1 ATF4	down	**
GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP	0.0001868	0.0016695	0.5188481	-0.3004170	-1.581336	170	LTA4H PTPRB MYADM RTN3 PLEKHA1 VAPA FRAT1 ZBTB2 ABCB1 RAP1A SERINC1 RB1 RGCC HNRNPDL CLK1 UBE2D3 RHOB FABP5 MED11 KLF4 SLC12A4 HNRNPUL2 ARHGAP9 PRF1 KLRD1 NUS1 CNOT6L DDHD1 PPP6C SF3B1 STAT4 CTSZ TYROBP SP3 DDX5 THUMPD1 TPP2 RHOQ ICAM2 CHORDC1 EPHA3 AZIN1 IRS2 ACTN2 RGS2 RNF2 CCR6 RPP30 PIP4K2A HSP90AA1 S100A4 RORA MIS18BP1 RNF13 SNRPG DRAM2 UBE2N BCL10 MATR3 MAN1A1 PAXBP1 MAP3K1 WDR26	down	**
GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP	0.0002301	0.0019774	0.5188481	-0.2997415	-1.580435	173	KMO OLR1 GAPT TMEM170B LYL1 CITED2 SPG21 SIRPB2 RAP1A PBX3 CSGALNACT2 LINC00909 MPHOSPH6 FBXL5 HMGN1 MTMR6 PLEKHM3 CD302 PINK1 SLC6A6 CDKN2AIP NCOA1 GZF1 CDC40 GABARAPL2 HECA PHF10 DDX17 TMEM251 PTGER2 ATP13A3 TUBGCP3 ZCCHC9 ZBED5 NDUFV2 GAS2L3 ATG2B MILR1 METTL14 IRS2 TBRG1 CD81 BRI3 KYNU SERINC3 BNIP3L CPQ FGF14-IT1 RTN1 DOCK10 PAIP2 TRAPPC11 SPOPL ZBTB44 CENPC MAPK1 ITGB1 FBXW2 PPWD1 HMGB1 PAXBP1 KLHL9 WDSUB1 PDPN SDCCAG8 DOCK5	down	**
GSE3982_MAST_CELL_VS_TH2_UP	0.0001899	0.0016890	0.5188481	-0.2991640	-1.580301	174	TBX3 FBP1 TIE1 EMCN PLEKHF2 PCOLCE2 IL1RN FRAT1 TGFBR2 CD36 ANXA1 ASAH1 PTX3 CAMTA1 SPRY2 CLK1 SPI1 ATP6V1H SORBS1 BST1 ZCCHC24 CPVL ITM2B DAB2 ARNTL TPP1 SOCS5 CLIC4 NPR3 GMPR PAPSS1 DSTN AFF1 LMBRD1 TMOD1 CYB5R1 HERC1 ZNF804A WDR7 ZNF175 GSAP AP1G1 KIAA0232 ZFYVE9 GNAI1 GALC HBP1 CCDC68 ABI3BP SERINC3 DOCK6 EPN2 GLUL TIMP3 TMEM87A TTC19 DNAJB9 SAMSN1 COL13A1 GRB10 EMC3 LYZ KLC1 PHYH CRTAP	down	**
GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP	0.0001899	0.0016890	0.5188481	-0.3000759	-1.579541	170	SLC16A4 MYD88 RPL23AP53 NR3C1 IL1RL1 RCHY1 RFTN1 IL23A ABCB1 IER2 ZEB2 HBEGF MAP3K8 KLF10 BTG3 PDGFA CD58 ADARB1 FABP5 PPT1 FOXO1 ADO GRK5 ATF3 TAF9 SMAD7 AFF1 RPL17 RBPJ JUN KCTD12 DDX17 IFNGR1 GSTO1 IPO7 CD83 REL TNFRSF9 ACSL1 CDK17 PKD2 STXBP3 TGIF1 CD6 GNG5 GABARAPL1 MACF1 PGGT1B CCL20 GEM ZNF143 SLC31A1 CEP170 SPARCL1 RAB5A TIAM1 DIXDC1 OSER1 MMD ZNF165 PUM1 NR4A2 SNW1 CYP51A1 UNC50 UBE3A TSC22D2 HMGB1 TES ATP8A1	down	**
GSE10325_CD4_TCELL_VS_BCELL_UP	0.0003421	0.0027593	0.4984931	-0.2978102	-1.579195	181	TRPV2 FYN SAMHD1 SLC39A8 MAL TGFBR3 GIMAP6 ANXA1 STOM GATA3 ZMYM6 RGCC TMEM123 SRGN PDE4D ATP10A ARRB1 LEPROTL1 ARNTL SOCS2 MGAT4A DOCK9 PDE3B VIM ID2 CCND2 PRF1 CCSER2 SH2D2A GNAQ VAMP5 TBC1D4 KLRB1 PHACTR2 IL2RB AQP3 STAT4 PLK3 PIK3R1 PTGER2 CALM1 CD6 PIM1 TOB1 SELPLG WDR1 TIAM1 PIP4K2A GIMAP5 GPD1L S100A4 CD3G DUSP7 RORA CCND3 LPAR6 GIMAP4 TNFSF8 SVIL TMEM43 AKTIP PRKCH ICOS	down	**
GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN	0.0032194	0.0167933	0.4317077	0.3730835	1.578680	111	ATP10B TICRR SIX4 TTK ANLN EIF2B5 LAMP5 PROC ECT2 CUEDC1 GAPDH SPATS2 XPNPEP1 RANBP1 POLA2 CLSPN SMYD2 RAD54L ANKRD13B EGFR PDZK1IP1 TBC1D8 DSCC1 PERP CAD THOP1 TNFRSF21 PODNL1 EFTUD2 TSNAXIP1 NHLRC1 PSME2 CCDC159 FAM71F2 CDC42BPG LRRC15 GNAL CES4A TTC12 TXNL4B SYBU APBA2 COX5B PGAM1 UQCRQ	up	*
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_UP	0.0005301	0.0039671	0.4772708	-0.3012032	-1.578287	165	CXCL3 IL1A DLC1 IL1B TRIB1 IL23A SLC19A3 RAPGEF4 MTF1 TNIP3 PRSS12 PTX3 SLC7A11 BTG3 PTAFR PLAUR SOCS2 MYO1B CLIC4 NFKB1 CXCL2 CCL4 DNTTIP2 INHBA IL7R PRDM5 HCK PROCR NINJ1 HCAR3 CD80 IL6 SOCS3 STAT4 TREM1 DNAJA1 WTAP TNFRSF9 ACSL1 EHD1 SERPINB1 FPR2 DUSP5 EWSR1 SOD2 ETS2 CCL20 ICAM1 HSPA2 TNFAIP8 IER5 MT1M NUP98 TRAF1 MAP3K4 NFKBIA SIGLEC9 FEZ1 DNAJB5 REEP1 FJX1 BHLHE41	down	**
GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN	0.0002392	0.0020443	0.5188481	-0.2972176	-1.577529	178	SLPI ST8SIA6 GLIPR2 SPN CLDND1 THBD INSIG1 MYADM GPCPD1 ZBTB2 IER2 EDEM1 SPG21 RRAGC ASAP1 UBL3 PICALM SRGN COQ10B TMED5 MAFG ERP44 ATF3 UBE2B PLEKHB2 PLEK PI4K2A LIN54 EMP3 SLC25A33 RYBP NEK7 IL2RB VAT1 SH3BP5 JUNB SKIL PNPLA8 TPP2 TBX21 ZCCHC9 ATP6V0D1 PIK3AP1 TGIF1 DUSP5 ATP6V1A CD86 GNA13 SYT11 PITPNA RNF2	down	**
GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP	0.0007955	0.0055928	0.4772708	0.3516899	1.575953	167	CCNO B3GALT5 FUT6 CDC45 GABRP EPN3 DEPTOR PBK NDC80 DNMT3B COL7A1 ESPL1 CUEDC1 SLITRK5 MCM2 TYMS COCH DTL INTS1 CEP55 ITGB4 SAE1 E2F2 ERAL1 SMYD5 RIPK4 SLC9A3R1 B3GNT3 TRMT2A GNPDA1 PML GEMIN4 NUSAP1 CBX5 FBXO41 ZNF500 PIAS3 PELP1 COG2 KIF22 SPTBN2 CCDC51 KRT19 MADCAM1 SPINK5 NSD1 LRRC14 BCL9 APOBEC2 TSC2 ANAPC2 ERBB2 UBAP2L ZNF142 PNKP CENPE IDUA MRPS27 FAM222B TRPC4AP MED16 GLI3 RUSC1 CNKSR1 KHDRBS2	up	**
GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP	0.0002224	0.0019211	0.5188481	-0.2973051	-1.575068	186	PLEKHF2 CTSW BMPR2 SLC39A8 ARL8B IL1RN FAM49A TMX4 UBR3 CACNA2D2 ASAH1 PBX3 KLF10 GRN CRK ZEB1 ARHGEF2 ATP6V1H REST PRKD3 KLF9 GAPVD1 SNIP1 MGAT4A NFKB1 CDS2 ELK3 HTT UBASH3B PAFAH1B1 SIAH1 FAM102B NCKAP1L SGK1 RNF141 NOTCH1 PIK3R1 GFPT2 BLOC1S6 NUP153 TSC22D1 NAB1 CD86 TAGAP GNA13 CSNK2A2 KAT2B TSPO BMP2K CDC16 TIAM1 PTCH1 MAP3K4 NPAT FNIP2 RORA IQGAP1 TOX2 DNAJB5 TMEM30A SVIL DYNC1I2 PLEKHA2 XRN2 MTSS1 FNDC3A POLR2B WDR26 C15orf48 CBFB PGF ALDH3A2 GSN BICD2	down	**
GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP	0.0008650	0.0059863	0.4772708	0.3491895	1.574656	181	SYT8 GGCT PHF14 SDK2 TSPYL5 MSTO1 FLAD1 IFT27 SRPK1 MAP7 WDR3 PSMG4 ZNF443 SLC25A39 RPAP2 CAD ZNF229 MRPL36 ERC2 DHX33 COA4 METTL3 TNRC18 CDC23 THNSL1 SLC35C2 FANCF WDR53 DNAJA3 PUS1 COG2 ZNF544 CCDC51 MAGOHB NAIF1 PALB2 YLPM1 FAHD1 MGME1 THOC5 DDX23 C1orf109 URB1 ESRRA SUOX DUS2 INTS8 MSH2 PRIM1 DZIP3 MRPS25 VPS33B SEC13 SUPT3H RPUSD2 TARBP2 RELL2 ZSCAN29 TRUB1 TAF4 MRPS26 RANGRF ALKBH2 KIAA0586 RTN4IP1 RCN2 MRPL12 EIF2B1 RBL1 MCEE URB2 GXYLT1 RMI1 TP53RK SWSAP1	up	**
GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN	0.0006665	0.0048462	0.4772708	-0.3006086	-1.574221	157	ACP5 SASH1 LY86 P2RY13 NCF2 CD22 SLC11A1 NCEH1 ADAM17 MS4A14 TTYH2 LAIR1 FOXJ3 PLXNA4 LAMTOR3 TCF7L2 ITM2B ZFAND5 TPP1 MGAT4A FCER1G DUSP1 DSE RUFY3 GZF1 SLCO2B1 SEC14L1 HPGDS CPEB4 HK3 CTSZ TYROBP LPCAT2 ATP13A3 ACSL1 TIMP2 ZFYVE9 SBF2 IRS2 GALC MACF1 ADAM10 SERINC3 PLA2G15	down	**
GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN	0.0003144	0.0025617	0.4984931	-0.2963497	-1.574146	177	EPAS1 HMOX1 EDNRB OSBPL11 ENG MYD88 SLC44A2 ASAP1 ADA MAP3K8 LITAF NDEL1 FABP5 STAT5A TIMM10B CCL22 CASP1 DAB2 ZFAND5 SELP C9orf72 CCL4 CD53 HTT CMTM6 INPP5B RAB8B JUN ST6GALNAC4 MAP4K4 PIK3R1 SNX1 UNC13B TINF2 AGFG1 KRTCAP2 CD86 MAP3K2 PIM1 ATP6V0C CCR1 STX12 TSPO IST1 BMP2K TNFAIP8 CEBPD HSPA8 CTSC MCOLN2 TLK2 NABP1	down	**
GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP	0.0014764	0.0091984	0.4550599	0.3605367	1.573883	134	CDHR2 SLCO5A1 CYP19A1 LAD1 AK4 GRIN2D RBBP8NL PRSS2 BRCA1 GAL3ST1 IGKV4-1 SIX1 EFNA5 NUB1 TMEM41A MUC6 IDO1 REC8 IFI44L PASK CC2D1A WWC1 STAT2 TNPO2 ZNF827 ZGPAT DTX2 MC1R CADM4 SPTBN2 TMEM30B MDGA1 USP18 DGKA LRRC17 GNG4 PARP14 MMP24 CES4A ADCY1	up	**
GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN	0.0004275	0.0033433	0.4984931	-0.3001492	-1.573576	171	RAB11FIP1 OSBPL11 MYADM FGR DNASE1L3 KIAA0355 DPEP2 SH2B3 GM2A JAM3 HNRNPDL HNRNPU ITSN2 ARL11 RAB14 KPNA5 DENND3 RBMS1 PTPRC ACTR3 SNN SERTAD2 IL6 WASF2 SNX29 CELF1 CCDC50 IFNGR1 DHX15 EEA1 IRF8 GMFG PRKCE FRYL FAM43A UVRAG KLF2 MBP XYLT1 HSF5 ADPRM RPL21 GNB4 ANKRD13A MBNL1 CCR6 ARAP2 OPN3 SIK3 TOB2 HNRNPK TLR10 CEPT1 PTEN	down	**
GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP	0.0004663	0.0036001	0.4984931	-0.2996961	-1.573451	167	CD55 TTC7B CD44 NEDD4L AQP9 S1PR1 ELMO1 CD9 GNPTAB NFATC3 FAM49A PDE2A ATP2B1 CYP17A1 RAPGEF4 C1orf21 ECHDC1 FOXP1 LAIR1 ZSWIM6 SELL PIK3R5 CNOT6L FRY SH3BP5 ETS1 ELOVL7 CCR7 PIK3R1 FRYL COBLL1 CD7 DYM TAGLN2 ICAM2 BIN2 C19orf38 SMPDL3B VAV3 PDLIM1 ZC3H12D RXRA RNF138 IL18 IL18RAP GPD1L B3GNT2 CYTH1 CCND3 SMAD4 ARHGEF18 TNFSF8 CX3CR1 KBTBD11 FAM53B	down	**
GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP	0.0006785	0.0049043	0.4772708	-0.3003664	-1.572953	157	IL1B SNX10 CCDC88A MYADM SLC15A3 PILRA ZEB2 PLA2G7 C1orf21 MPHOSPH6 LAMTOR3 ZFYVE16 SRGN PDE4D BAG1 NRARP MPEG1 BST1 COQ10B ITIH5 HOPX ID2 CCL4 PRF1 SMNDC1 INSL6 MTPN AREG CREM SAR1A TREM1 EEA1 LYRM1 COBLL1 NKG7 KLRC2 XYLT1 CHPT1 NAB1 GABARAPL1 PHF11 ACADL RNF2 GEM ARAP2 IL18RAP NFKBIA AIM2 RORA EMC3 EHD4 PMAIP1 SCLT1 TSTD3 NR4A2 CX3CR1 ICOS ITGB1 SH3GLB1	down	**
GSE3982_DC_VS_TH1_DN	0.0006596	0.0048036	0.4772708	0.3498062	1.572206	178	ABCC2 ASB4 CENPF POLQ PBK PMS2P5 CENPA PTTG1 SFXN1 CCNB2 STC2 TYMS ORC1 GINS4 AGK CLDN1 HMMR BUB1 AURKA KIF2C PASK CHAF1B CHEK1 DNAJC9 THYN1 PERP PARP1 DNAH6 BIRC5 TESC RBCK1 FGFR1OP UNC45A HSPA4L DLGAP5 PINLYP PRMT7 FKBP14 MAGOHB COX10 SUPT16H YLPM1 TWIST1 PELO MYO5C THOC5 PRMT1 PRODH PIP5K1A DOLPP1 LSM4 ATAD2 GLO1	up	**
GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP	0.0002172	0.0018932	0.5188481	-0.2953229	-1.570855	187	CXCL16 MCOLN1 KLF13 DDX6 ZCCHC2 PAFAH1B2 CTDSP1 TBC1D2 CBL FRAT1 GGA2 TXNIP FBXO7 LINC01010 IFI30 ZNF503 BFAR UBE2D3 ARL11 FABP5 REST FKBP15 NUS1 NRBF2 CD300LB PI4K2A STK24 ST6GALNAC6 TMEM9B MED28 SH3BP5 CAP1 KIAA0232 FEM1B DOK2 TMEM70 CCR1 PLEKHO2 TMA7 AMD1 SERTAD1 ELOVL1 ARRB2 BLOC1S2 ACTB SP100 HAVCR2 G3BP2	down	**
GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN	0.0006707	0.0048636	0.4772708	0.3494622	1.570660	178	FOXM1 TICRR TROAP BUB1B TTK RACGAP1 E2F8 CCDC14 POLE PLK1 CDCA8 FIGNL1 THTPA PRKCA XRCC2 TMCC1 ZFYVE19 GINS4 WDR90 CCDC77 EME1 MCM7 CDCA5 RAD54L PASK HEBP2 PDZK1IP1 ORC6 CKS1B CBX5 PPIC POLE2 CCDC61 CENPJ C1orf112 SPAG5 TTC23L TRAF5 DIAPH3 FANCG OR10AD1 FANCF RHBDD3 KIF20B CCDC51 POLD1 ATAD5 PALB2 CENPM FAF1 CKAP2 TDP1 NFE2 PSMB4 STK39 MSH2 LRP11 PRIM1 DZIP3 RFC5 TPGS2 MCU	up	**
GSE27786_LIN_NEG_VS_NKCELL_UP	0.0009213	0.0062426	0.4772708	0.3517615	1.570400	164	CEP72 BDH1 CCDC34 C12orf66 EIF2B5 DIO2 CCNF KIAA0895 CCDC150 KNTC1 FBF1 NUP155 METTL7B SAE1 SYCP2 GPSM2 MORC2 TOPBP1 BACE2 PPP5C PES1 CDK1 CENPH C1orf112 LRRC42 DIAPH3 PPP1R36 OR10AD1 MGMT DAP3 RHD RPRD1B IARS2 SIRT4 SRRT WNT10B MGME1 ODF3B NOB1 LANCL2 PRODH CREB3L2 RHOBTB1 STRBP FARSA BLVRB MLLT1 AGBL5 SMPD4 ZNF205 PWP1 MRPL48 NUP93 GSDMC CLNS1A PDXP ZDHHC13 HRAS PCNT ADSL ZNF771 FOXRED2 TEFM AP1B1 LRP8 AP2A1 TIPIN TXN2 DTX4 TIMM9 SLC28A3 INTS9	up	**
GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP	0.0004471	0.0034742	0.4984931	-0.2994026	-1.569662	171	SLC6A4 CXCL3 ABHD5 CLDND1 HSD17B6 SIK1 CDH5 FOLR1 EGR2 NEDD4L QKI PRPF38A CCNL1 EDEM1 SLC44A2 ASAP1 SLC25A17 CLEC7A CSRP1 RANBP9 BFAR GPBP1L1 ZBTB8A PRKD3 SLC7A8 STX3 VRK2 ITGAX ARL4A SPRYD7 PTH1R HEXB PKIG SLC25A25 PHTF2 CTSZ GYPC MSANTD2 NAP1L5 TIMP2 SAV1 NDUFA5 VPREB3 RGS2 ATAD2B NEK1 SLC34A2 NBN CALHM2 TBC1D1 G3BP2 STK4	down	**
GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP	0.0003901	0.0030957	0.4984931	-0.2976709	-1.569077	172	CD52 PECAM1 DDX6 YPEL5 MAL FRAT1 ATF7IP2 DPEP2 MALAT1 PPP3CA AGO4 TLE4 LINC00528 DENND6A LEPROTL1 STK17B ARNTL LAPTM5 NR1D2 PNRC1 SH3BP5-AS1 PINK1 IL7R PIK3R5 CNOT6L C16orf54 ARHGDIB SNN PIAS1 CREBRF KLRB1 UTRN AQP3 AK1 GLIPR1 PIK3R1 HERC1 IDS ENTPD4 KLF2 YPEL2 MBP FOXO3 GSAP TSC22D1 HBP1 GPR18 SPOCK2 SLC35D2 CXCR4 EPHA4 IFFO1 SSH2 CYTH1 ZBTB40 ARRDC2 ARHGEF18	down	**
GSE17721_CTRL_VS_LPS_1H_BMDC_DN	0.0003521	0.0028306	0.4984931	-0.2996898	-1.568958	162	EREG OSBPL1A SOWAHC ZC3H12C F2RL3 DDX6 CITED2 MTMR10 IGSF6 IL23A IER2 CCNL1 MAP3K8 LUZP1 PTX3 NR4A1 NFE2L2 BTG3 TIPARP MEFV CDKN1A ATF3 AQP4 C9orf72 ID2 INHBA MAFF NRBF2 PROCR MTPN KIF13A OASL JUN PPP1R15A PTGER4 FOS SLC4A5 RIN2 CHORDC1 EPHA3 EHD1 DPM1 SBF2 TSC22D1 IRS2 CCR1 KIF17 CALB1 TAGLN CCR6 ICAM1 OSR1 PIP4K2A RIPK2 KCNJ9 B3GNT2 DNAJB9 NABP1 BHLHE41 CHIC2 CLEC4E FPR1 ZFP36 EFNB2 DNAJB4 SYCP3 TOR2A GABPB1 DLD NKD1 CLVS1 UFSP2 CFLAR EBI3 DUSP2	down	**
GSE3982_NEUTROPHIL_VS_TH2_UP	0.0005275	0.0039540	0.4772708	-0.2997766	-1.568446	153	NOVA2 STAC SLC12A6 DENND5A FBP1 LRRFIP1 ZCCHC2 SPATA1 SLC11A1 DPEP2 SLC7A7 RAB33B DACH1 TOR1AIP1 TRAF6 CLK1 UBE2D3 EVI2B CFD KLF4 CEBPA SPAG9 SEC24B LAPTM5 CDS2 ACTR3 CAPZA2 EVI2A ARL4A GNAQ MARK3 FOXN3 NECAP1 SH3BP5 LTBP2 HK3 RAC2 TREM1 PSTPIP2 OGFRL1 APH1B	down	**
GSE34515_CD16_POS_MONOCYTE_VS_DC_UP	0.0002727	0.0022847	0.4984931	-0.2947583	-1.567359	185	ACVRL1 LPIN2 FYN LONRF1 AKAP7 BMPR2 SFR1 TEX2 TRA2B CD5 LMNA KLF6 NDEL1 HNRNPDL ZMIZ1 KIF1C ITM2B STK17B FMNL3 PER1 B9D2 PRICKLE2 KPNA3 TP53BP2 NRBF2 LMBRD1 ACTR2 SACM1L MOB4 SAR1A PHTF2 DDX17 JUNB MCM9 FYTTD1 TTC14 IDS ATL2 DYM EPC2 AGFG1 NKG7 RIN2 BAZ2B CEP76 KHDRBS1 NAB1 CSDE1 PPIG CRY1 SPOCK2 SERINC3 MIER1 ABL2 TNFAIP8 ITPRIPL2 HSP90AA1 LYSMD3 FDX1 NFKBIA PRKG1 ANXA11 NR3C2 PPP1CB FNBP1 CHIC2 TMEM30A ZNF800 FUS ITGAL CMPK1	down	**
GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_DN	0.0013503	0.0086447	0.4550599	-0.3123111	-1.567087	131	KRT81 SEMA6B EPAS1 CYP27A1 RAMP2 CD44 RTN3 DDO LMNA EIF1 FOXC2 CYBRD1 MAP2K3 YBX3 PINK1 MATN2 MPC1 CMTM6 SLC25A3 VAMP3 NXF1 RAB31 ATP6V0B PABPC4 SPATA2L MFAP4 BTBD7 SMPDL3B EPB42 SOD2 RGS2 TMA7 DOCK6 PITPNA EIF3F BNIP3L ALDH1B1 PKNOX2 NRG1 DNAJB5 TNFRSF10D RABGEF1 EXOG CHP1 EIF3L AOAH EFNB2	down	**
GSE10325_CD4_TCELL_VS_BCELL_DN	0.0004782	0.0036575	0.4984931	-0.2985572	-1.566526	161	KMO SWAP70 HHEX LTA4H LYL1 LY86 PLEKHF2 LMO2 GFOD1 SLC15A3 MEF2A CD1C CD22 GGA2 SLC7A7 ENTPD1 GM2A MS4A1 GNG7 TUBB6 TBC1D9 SYNPO YBX3 DENND3 CLIC4 HLA-DQA1 TBC1D5 SNX3 ARHGAP17 PKIG RNF141 JUN RHOBTB2 STX7 CD83 IRF8 CDK14 PLCG2 RHOQ IRF5 TFEB VAV3 TCF4 CD1D VPREB3 PDLIM1 CLCN6 OPN3 SPIB SCPEP1 METTL7A CD19 AIM2 EHD3 BANK1	down	**
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN	0.0025081	0.0138700	0.4317077	0.3626350	1.565021	126	PKHD1 LAD1 DCST1 CBY3 SOX2 MUC16 GUCY2C MRPL46 ASPM ANKRD22 RAB36 DPYS TMEM184A WDR73 C11orf16 SARS2 PLXNA1 EHHADH AFAP1L2 MEA1 KCNE3 TNFRSF25 SYN3 BPGM COL3A1 NPHP1 UQCRFS1 VWA5B2 MNS1 NGFR SPAG1 DNAJC11 CLTB ZNF248 NOB1 SIRT5 PKDREJ MYH3 CDH11 PRSS53 TMEM17 BCL9 ALMS1 JAKMIP3	up	*
GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN	0.0014097	0.0088845	0.4550599	-0.3021686	-1.563998	145	OLR1 ZC3H12C SNX10 SAMHD1 PAFAH1B2 IL1RN DNASE1L3 SBDS PPP1R15B ITGA5 NDEL1 SRGN ATP10A ZFAND5 TNFSF15 RMDN3 ATF3 PIK3R5 PROCR IL6 ENPP4 PCGF5 GYPC MALT1 AP3B1 HIVEP2 TREX1 SAV1 MRPL39 NAB1 SOD2 GNA13 IST1 ALDH1B1 SETDB2 ATP9B TRAF1 MAFK EDN1 AIM2 SAMSN1 MIER3 RABGEF1 SPSB1 SERPINE1 TNFSF8 SNW1 CD69 SSC5D NMI IRF1 SLC23A2 ROBO2 CFLAR NFKBIZ RNF19B	down	**
GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP	0.0002155	0.0018813	0.5188481	-0.2938675	-1.563929	184	EGR2 BCL2A1 CD9 HPS5 ATP2B1 LTBP4 ADAM17 GLS EIF4E IL18R1 NFE2L2 NDEL1 ZFYVE16 SRGN CD58 EVI2B MAP2K3 ACSL3 PRKD3 VASP SPAG9 PER2 NFKB1 ATF3 CDS2 VIM CCL4 MATK CALM2 MAPRE2 PPP2CA NSMAF PNO1 CD48 GABPA CYCS RHOG TMEM251 IPO7 SP3 IDS HOMER1 NOL7 HIVEP2 PEA15 DUSP5 GNAI1 ATP6V1A PDCD1 GNG5 UTP3 PHLPP2 CCL20 AMD1 WDR1 CEP170 UBE2D1 TRAF1 COPS8	down	**
GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN	0.0003286	0.0026546	0.4984931	-0.2965272	-1.563487	173	CXCL3 IL1A IL1B ARRDC4 PDE1B CALCRL C5AR1 HMGCR IL1RN TNFRSF8 HBEGF SLC25A17 ITGA5 RBM4 MAP2K3 STAT5A TNNC1 PLAUR ITPK1 PER2 CDKN1A CCL4 PER1 DUSP1 AFF1 MAPRE2 ACTR2 PROCR NCKAP1L RPS6KA2 MYO1C TULP2 SOCS3 SKIL THUMPD1 ENTPD4 TNFRSF9 SNRK RRN3 EHD1 PIM1 TMEM70 STK40 RIMKLB POLK ETS2 IL18RAP TIAM1 TRAF1 NFKBIA GTF2F2 MT2A PSMD9 PIM3 EGR1 SERPINE1 CNR2 HIPK1 ZFP36 MT1E	down	**
GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP	0.0013708	0.0087298	0.4550599	-0.3066113	-1.563325	138	CXCL3 EREG PRX IL1A SASH1 DENND5A USP12 ZC3H12C RAPGEF2 STX11 BCL2A1 LIFR LATS2 MAP3K8 TTYH2 NPNT TNFSF15 DRAM1 KLF7 NFKB1 IRAK2 ZBTB43 DUSP1 LRRC3 CPLX1 RASGEF1B SNN KANK1 HESX1 DDX60L IL6 OASL STAT4 PTGER4 SKIL PI4K2B PALMD ACSL1 PELI1 GPR84 ADORA2A-AS1 GEM ARAP2 IL18RAP MIR155HG PUS10 ADORA2A MCOLN2 TNFSF9 AIM2 C21orf91 NRP2 GSG1	down	**
GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_UP	0.0003154	0.0025656	0.4984931	-0.2922891	-1.563265	183	EPAS1 SLPI ACP5 KMO RAMP3 ACVRL1 LIPA LY86 GTF2I CLEC10A MSRA TGFBR3 TGFBR2 DNASE1L3 ARHGAP29 ARSB RAPGEF4 ANXA5 RGCC CRTAM SCP2 MPEG1 OSTF1 ZADH2 PDE3B ID2 PRF1 FCER1G ALOX5AP KLRD1 PPP2R5A HLA-DQA1 TANC1 SNN TMEM9B PKNOX1 SGK1 SNHG8 TYROBP ELOVL7 CCR7 GMFG GPR183 RASSF2 WDFY4 RUNX3 ICAM2 C19orf38 TEC TSPAN14 ANKRD13A FCGRT GPR18 PDE4B PITPNA SPIB SETD4 TDRP COMMD8 DUSP7 LYST THEMIS2 EHD3 FEZ2 SUGT1 SPSB1 CTSH	down	**
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_UP	0.0023267	0.0131170	0.4317077	0.3609204	1.563205	128	GABRB3 PRTFDC1 C6orf141 PMS2P5 ASPM C1orf220 BTRC RPAP1 CENPL ZNF766 SYCP2 ANKRD52 RBM28 IL20RB ZNHIT6 XXYLT1 BMS1P1 GET4 HSF2BP C4orf47 NRG4 MYOT PPM1E MCTP2 KCTD7 ULBP2 ANKRD54 SLC35F3 L3MBTL3 ZNRF2P1 DTYMK PLAC4 WDR34 SIRT4 ZNF76 ZSWIM8 TMEM147 LRRC73 AMT TMEM253 LINC00964 TUBGCP4 VPS9D1 PTPRF ENPP5 CHPF2 DCAF11 E2F7 ZNF253 ACTR5 PHRF1 VPS18 PTPRK LOXL1-AS1	up	*
GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP	0.0003264	0.0026414	0.4984931	-0.2941241	-1.562584	179	SGK3 USP12 CTDSP1 TBXA2R S1PR1 NR3C1 DENND2C RFTN1 TXNIP ZBTB4 CNST CLCF1 GM2A FOXP1 PAG1 EPM2AIP1 MCL1 TIPARP CDADC1 FOXO1 TCP11L2 KLF7 NR1D2 SELL CD302 PNRC1 SHE IL7R ADD1 MCMBP SNHG8 RPL9 WTAP ELOVL7 CCR7 ATXN1L SKIL ENPP4 RC3H1 CEBPZ LETM2 FOXO3 ICAM2 ZRANB1 PHF2 CLCN6 PDE4B	down	**
GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP	0.0017373	0.0103474	0.4550599	0.3488214	1.562569	169	HELLS ELOVL6 TROAP BUB1B XYLB KIF18B CDCA2 ANLN PLK1 CDCA8 ECT2 NCAPD2 TTLL4 C19orf48 KIF23 OSBPL2 AURKA SLC29A2 IDH2 KCNJ2 SKP2 CDKN2C PABPN1 KCNE3 AP3D1 GMNN OAT SLC25A13 EZH2 NUP205 POC1B RNF150 FGFR1OP PLEKHG3 TK1 PKP4 ATAD5 SLX4 NAT9 NR6A1 PFAS CDC20 ACLY ZRANB3 URB1 SLC41A3 CCNA2 TRERF1 DNPEP SNX8 PNKP EIF4G1 FRMD6 TRUB2 KIF24 NCAPH POLRMT USP20 MLH3 CRAT HDAC10 TRPS1 TLCD1 GAK SAFB2 SMAD3 NLRC3 REEP4	up	*
GSE3982_NKCELL_VS_TH2_UP	0.0009597	0.0064761	0.4772708	-0.2980563	-1.562110	159	EDNRB WFDC1 IL1B F2RL3 PTPRE FYN CD44 FCER1A PCOLCE2 C5AR1 CLEC10A MANBA AGPAT4 FAM49A ANXA1 PTX3 GPBP1L1 STOM GPR4 CLEC1A KLF4 DRAM1 CEBPA DENND3 TPP1 NPR3 MYO15B FRMD4A IL7R SNN PROCR WASF2 CD160 KLRB1 CYB5R1 LTBP2 HK3 RAC2 AK1 ENPP4 MARC2 VAV3 TSC22D1 CDC37L1 ACTN2 RXRA ZNF143 XKR8 MFAP5 GLUL DAZAP2 NRG1 ZBTB44 DCUN1D2 UBAP1 AOAH ITGAL KCNJ1 FAM53B	down	**
GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0017778	0.0105371	0.4550599	0.3489933	1.561654	166	PRLR PARPBP BUB1B ZNF280B MPP6 PHGDH BET1 GINS1 ANLN AP1S1 SHMT2 NCAPD2 ZFP64 CDK5RAP3 EXO1 KCNN4 POLD2 TTLL12 GCAT PKM KIF11 TRPT1 SEC61A1 PYCR2 KDELR2 DSCC1 ALG3 TMED3 CDKN2C UCK2 GOT2 PSMB5 BPGM UBFD1 ST14 ALDH7A1 NMRAL1 SND1 COPS6 CENPK RNF187 MAN2A1 STAMBP PYCR1 ZWILCH SLC12A2 ENTPD7 DNAJC10 NMT1 SRPRB NCAPD3 KCNK6 NCAPH DHDDS TFG EIF2B1 PNPO TM9SF1 PTGR1 TMEM214 ALPK2 TIPIN PLOD3 NUDCD1	up	*
GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_DN	0.0006160	0.0044929	0.4772708	0.3478956	1.561499	177	HJURP BUB1B NEK2 NDC80 BET1 RACGAP1 KIF14 ANLN POLE TPX2 PRC1 EIF3B TNC WDR62 CISD1 MKI67 KNTC1 AURKA E2F2 MMS22L CKAP2L URI1 HDGF CENPH C1orf112 TNFRSF25 AAGAB POC5 FEN1 NUP205 SF3B3 SNRNP25 NMRAL1 MNS1 XYLT2 TRIO C15orf41 NADSYN1 TSTA3 CDC20 RRP9 CKAP2 TFAP4 ALG8 ZNF286A RTEL1 FKTN ARHGAP11A RPRD2 NDUFS8 UQCRQ SMC2 NMT1 UBE2C NPEPL1 KCNK6 RPL23A TNFRSF1A VPS16	up	**
GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_DN	0.0007057	0.0050633	0.4772708	0.3467072	1.561352	182	HELLS RUVBL1 CHCHD6 MRPL46 CCT2 RANBP1 C19orf48 NLE1 QTRT1 WDR3 POLD2 WDHD1 AIMP2 SLC25A39 TRMT2A EEFSEC SNAPC4 MTG1 MRPL36 HDGF CCT3 GMNN ZMIZ2 E2F1 MRPS2 ANKRD26 LIPT2 UQCC2 PA2G4 TELO2 POFUT1 EXOC7 PDCD11 PUS1 SNRPA UROS COPS7B METTL22 GK5 POLD1 COX10 ELAC2 PFAS PPHLN1 ROMO1 CAPRIN2 LSM7 NEK4 NEURL4 RCC1 ABCD4 C1orf122 SF3A2 TSR1 LRRC14 DCPS MRPL55 PCBD2 CLUAP1 ZSCAN22 ACP1 DTNBP1 SMPD4 PPP1R14B PCTP GEMIN2 POLRMT SHQ1 EIF2B1 CAMK2G SDHAF1 OPA1 URB2 DHRS4 SHMT1 HDAC3 HNRNPAB NCOA5 LRPPRC TP53RK BNIP1 DHPS	up	**
GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN	0.0004726	0.0036301	0.4984931	-0.2958839	-1.559657	172	RAB11FIP1 RTKN2 SC5D IL17RB SWAP70 SNX10 CLDND1 TBC1D2 NEDD9 TRIB1 RFTN1 HBEGF MAP3K8 RANBP9 TFRC MAP2K3 TNFSF12 UHRF1BP1L SOCS2 ERP44 IRAK2 SMAD7 GCA MBD2 STK24 PHTF2 SGK1 IL2RB HCST SH3BP5 DESI2 RAC2 LYRM1 OSM TNFRSF9 RALB TAGLN2 RUNX3 PKD2 MYL12A PEA15 KAT2B PDE4B LDLRAD4 CTTNBP2NL MIR155HG ELOVL1 SEC61B METTL7A COPS8 PDE4A DLST ETFDH CSF2RB CTSH ZBTB8OS	down	**
GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_UP	0.0015641	0.0095783	0.4550599	0.3524637	1.559657	151	MUC13 HP SLCO5A1 CNGA1 FOXA3 BIK CEP89 HOXD8 HOXB6 SLC2A1 TBRG4 IQGAP3 TRAIP CHRNA7 PTTG1 FIGNL1 AGR2 FAM220A ITGB4 SYNE4 SMYD2 SNHG11 CDC25C TARS2 SMYD5 KCNJ11 POLR1C MECR ALX4 SLC35C2 ATP9A MBD4 YIPF3 DHODH ASGR2 PTGER1 FHL2 LIPC ENPP2 MAT1A CDC20 FAHD1 TIAM2 EXOSC5 IL7 MMP16 RCN3 TMEM141 GTPBP2	up	**
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN	0.0008385	0.0058441	0.4772708	-0.2963094	-1.559509	169	GPATCH11 PAN3-AS1 TUBD1 GLTPD2 EGR2 PRPF38A S1PR1 BCL2A1 PPM1D IL23A KLF10 ZNF410 MED19 NR4A1 LCMT2 ADO TACR2 EVI2A SH2D2A SLC25A32 MIR17HG GLB1 CREM CRNKL1 ARL5B ELP5 GPR183 KBTBD8 FAM177A1 EPC2 GIMAP1 BAZ2B NAB1 C16orf72 GPR18 ZNF267 FAM98B GEM EXOC2 MIR155HG TXNDC15 TEX10 FBXO30 USH2A ZNF165 NABP1 LPAR6 DNAJA2 PUS3 TMEM184C EGR1 ALG2 CHAC2 BCL10 ZNF347 TRMT10C TMEM165 FNIP1 NR4A3 IRF4	down	**
GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_DN	0.0045749	0.0226515	0.4070179	0.3678122	1.558995	114	AK4 SLFN13 ANKFN1 CHRNG IFT27 SAMD15 H19 SLC4A8 CLDN1 NLE1 TIMD4 PMS2P4 KLHDC7A CACNA1G MPHOSPH9 TOM1L1 LINC00857 FAM151A NEK11 C7orf50 FDXR MIPOL1 LINC00894 SLC25A13 FAM205A RTP4 ANKRD45 TBX1 ZNF233 CCDC130 HECTD1 PROCA1 TMEM72 ZNF436 DLEC1 CAPN10 KCNQ3 VWA1 TONSL IGLV3-19 TRUB2 PCGF6 DHX57 AKAP9 TLE2 RAG1 DCAF4L1 DHX32 SOCS2-AS1 CACTIN ZNF17 FGF1 DPYSL3 PACRG	up	*
GSE24726_WT_VS_E2_2_KO_PDC_DN	0.0004459	0.0034704	0.4984931	-0.2934677	-1.558837	177	SLC31A2 ACP5 PECAM1 HVCN1 EGR2 HCAR2 GTF2E2 AKAP7 SLC11A1 DNAJC3 ADAM17 CYB5A EMILIN2 LITAF PAG1 CLN5 TOR1AIP1 NFE2L2 TIMM10B BNIP2 DRAM1 KLF7 MGAT4A PLEK RAP1GDS1 UBASH3B PIK3R5 FKBP15 HLA-DQA1 MMP19 ST6GALNAC6 METAP1 RNF149 VPS37A PKNOX1 CNNM2 JAK1 SDHD FAM177A1 TAGLN2 TRAPPC10 TESK2 NFYC STK40 ME2 FAM98B RLF CEBPD TXNDC11 ZDHHC21 TRAF1 ISCU PLGRKT SAMSN1 NRP2 ARRDC2 CYBA EGR1 ING1 AOAH	down	**
GSE13522_WT_VS_IFNG_KO_SKIN_DN	0.0024860	0.0137631	0.4317077	-0.3313647	-1.558195	85	MGAT3 NOVA2 SOSTDC1 FBP1 PTPRE THBD FUT1 FBXO3 ACSM1 CBL RBM7 RAB33B NLK SLC25A37 ZYG11B PTPRO PEG3 ADAMTS9 NPAS3	down	*
GSE39556_CD8A_DC_VS_NK_CELL_DN	0.0002729	0.0022847	0.4984931	-0.2949560	-1.558073	174	CXCL3 KMO CD55 SIK1 FIG4 FOLR1 S1PR1 CD22 TGFBR2 TMX4 DNASE1L3 ZEB2 KIAA0355 ATP2B1 SH2B3 TACC1 GRN MCL1 GPM6A ADARB1 MTMR6 PTPN21 BNIP2 PIP5K1B PTAFR TJP1 CXCL2 SMAD7 HCK BTG1 EMP3 RPS6KA2 MYO1C SERPINB8 APBB2 STX7 CRYM UVRAG DENND4A XYLT1 NIPA2 PDLIM1 AOX1 APLP2 SBSPON RGS2 GPR18 TNFAIP8 CCDC69 SPIB ESYT1 TBC1D1 SP100 METTL7A CD19 LYST CYTH1 RNF13 EVI5 SETX HERPUD1	down	**
GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP	0.0002939	0.0024228	0.4984931	-0.2930496	-1.558059	180	GCOM1 FYN INPP5K IL1RL1 NCF2 UBL3 EIF1 RAB33B GNGT2 PPP3CA CCNI ZMIZ1 REST FAM49B CDS2 HPSE CEP57 ZBTB43 PLEKHB2 GNAQ IKZF5 CDKN2AIP AFF3 PIAS1 NRROS PIKFYVE SF3B1 CPEB4 KCTD12 IDS COBLL1 TPRA1 CELF2 AZI2 SRSF6 UBXN2A TGFB1 TFEB CD1D VPREB3 DUSP5 RNF138 SF1 SFT2D1 THAP6 TAB2 TOB2 SSH2 PLGRKT CEPT1 CD3G SKI TTC19 CYTH1 RPL18A CNOT8 BANK1 PPP1CB RABGEF1 ZNF326 DUSP6 HCFC1R1 FAM8A1 TUBA1A ATP1B1 RNF167 BCL10 RCSD1 STX16	down	**
GSE360_CTRL_VS_T_GONDII_DC_UP	0.0005931	0.0043479	0.4772708	-0.2966251	-1.557327	167	CD52 PNPLA6 STAC PECAM1 OSBPL1A HHEX LTA4H LYL1 LPL EGR2 FUCA1 TGFBR2 GGA2 TXNIP UBL3 PICALM SLC19A1 CRTAM APOC1 RAB14 ADARB1 EXOSC9 EFCAB14 MSR1 TNFSF12 ZCCHC24 CPVL PINK1 HEXB NCKAP1L PRCP KLRB1 LRRTM2 PIKFYVE CAPN11 KCTD12 DNASE2 BAG5 PPM1F PLCG2 ALDH3B1 RIN2 KIAA0232 ZBTB1 CTNNAL1 ATXN1 DOK2 CLEC2B PLA2G15 RXRA GPX3 VASH1 ESYT1 S100A4 METTL7A CD1E P2RX1	down	**
GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP	0.0004853	0.0037059	0.4984931	-0.2954131	-1.557176	172	ACVRL1 OLR1 HVCN1 WFDC1 MYD88 CLEC10A PRPF38A FGR RBM7 ARHGAP10 SSTR1 TTL CLEC7A KLF10 ANPEP NFE2L2 EPB41L2 ATP10A RHOB PTGIR DUSP3 MEFV BNIP2 CDKN1A RBMS1 ITGAX RRP8 SS18L2 DUSP1 INHBA BCLAF1 KCNA5 TMEM9B SLC25A25 APBB2 CD151 SLC3A2 ATG3 KLRC2 TIMP2 UBXN2A CBFA2T3 GNA13 KTI12 GEM ICAM1 MOB3B	down	**
GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	0.0004210	0.0033083	0.4984931	-0.2933773	-1.556953	176	ARHGAP31 PECAM1 BDNF INPP5K QKI CRY2 AKAP7 AGPAT4 ZBTB2 RCHY1 PDE2A CD36 CD33 CSGALNACT2 STOM LAIR1 HNRNPDL SRGN AGO4 TBC1D9 LRRC57 KLF7 ZBTB43 CPT1A FAM76B RSRC2 SERTAD2 SRSF3 HERC1 ZCCHC9 SLC3A2 NOP10 FAM204A TFEB CHRAC1 SMCR8 MIA3 NFYC BRI3 WBP2 ATAD2B GTF2B GEM PCM1 PIP4K2A GPD1L JMJD1C KIT FOXJ2 THRAP3 MCOLN2 TMCC3 ITCH PUM1 SMAD4 NIPSNAP3A MED31 AFTPH SETX HIPK1 ANKS1A DNAJB1 MAP4K2 MTSS1 RCSD1	down	**
GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_DN	0.0003668	0.0029346	0.4984931	-0.2949584	-1.555215	173	EPAS1 ST8SIA6 GPR65 HSD17B11 KLHL8 ST3GAL6 CLYBL NEDD4L TBXA2R DNAJB14 TXNIP ZBTB4 CLCF1 BMP1 BTG2 SERINC1 ACOT2 FOXP1 KLF6 PRSS12 PAG1 LAIR1 CYP4V2 PPM1K TCP11L2 PDE8A MGAT4A MARVELD1 ID2 IL7R PIK3R5 SGK1 RNF141 NDNF RHOBTB2 CCR7 GLIPR1 DDX5 LETM2 KLF2 MBP FOXO3	down	**
GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP	0.0021296	0.0122066	0.4317077	0.3512892	1.554678	154	PRR15 TFPI2 FOXM1 NEK2 SLC5A1 GTSE1 UBE2Z TENM2 ASPM AP1S1 CENPA LSR GALNT10 HNF4G SPPL2B DNPH1 TP53BP1 COPG1 CENPL SYNE4 CHAF1B CDC25C CAD REPIN1 PPP5C FLNB NRTN THOP1 ZNF32 POLE2 E2F1 MECR SPAG5 LMNB2 RAD51D TK1 CDC7 KLC2 CENPV TUBG2 RRP9 BLCAP PIGU CACNB3 DOLPP1 PDIA4 PI4KA MRPL55 FARSB STK25 ACP1 ADCY6 CAPN9 NELFA SART1 RAD1 AZGP1	up	*
GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_DN	0.0007754	0.0054854	0.4772708	-0.2966940	-1.554660	165	FCN1 SGK3 PID1 AATK INPP5A SFR1 RBM14 PRPF38A CD36 TNFRSF8 TACC1 ZDHHC2 AHRR PARVG REV3L CYB561A3 ZNF410 CRTAM ATP10A GMEB1 MSR1 CASP1 BST1 ERP44 HPSE TLR4 ARAP3 CCDC59 PIK3R5 MARK3 IKZF5 NCOA1 RBP7 CD48 ZNF555 SNRK ASTE1 ATP6V0D1 ATPAF1 ING3 CHRAC1 TESK2 HNRNPH3 DOK2 CHMP3 CDKN1C CREBBP ANKRD49 GSG1 LPAR6 SETX JDP2 CHML TNFSF8 CCDC112	down	**
GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP	0.0006103	0.0044577	0.4772708	-0.2965379	-1.554643	171	GPR17 HVCN1 PTP4A2 ARRDC4 COQ2 ELF2 SFR1 MTMR10 MOB1B RBM7 CACNA2D2 ARSB SWT1 RAB33B ZDHHC2 RANBP9 CRTAM AHNAK HNRNPA3 STK17B ABCC4 UBQLN1 TMBIM1 LRRC40 ZBTB43 ARL4A MATN2 UBASH3B BACE1 CDKN2AIP SRF BTG1 MYLIP YBX1 RHOBTB2 MAP4K4 THUMPD1 CD7 NAA30 CDK17 FAM204A C19orf38 ZBTB1 TSC22D1 TOB1 LTBP1 DISP2 SRSF10 SDAD1 MAP3K4 KLRK1 THRAP3 GPR171 DUT PIEZO1 HNRNPH1	down	**
GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN	0.0003127	0.0025517	0.4984931	-0.2934353	-1.554566	186	ST8SIA6 ACE TSPAN4 CD44 SEC22C LONRF1 QKI CTDSP1 HMGCR P2RY13 RFTN1 HEG1 CLCF1 DNAJC3 ABCG1 PAG1 LAIR1 RGCC TXN ZMIZ1 HNRNPA3 PIP5K1B RIT1 PDE3B HNRNPUL2 VIM MPC1 HCK PLEKHA3 SH3BP5 PHF10 CUL4A OSBPL9 RPL9 PI4K2B IDS RBM22 ATP13A3 TRAK2 PPM1F MBP TRAPPC10 STXBP3 SAV1 KCTD10 NFYC CD81 PGGT1B SERINC3 POLK DOCK6 BMP2K B3GALNT1 ATP9B FBXO25 IFFO1	down	**
GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP	0.0002746	0.0022914	0.4984931	-0.2951952	-1.553850	170	HSPB7 USP12 BMPR2 BCL2A1 DNAJB14 GNGT2 LCP1 SIRPA CRK RAB14 KIF1C CSRNP1 MTMR6 VASP DENND3 VRK2 MARVELD1 IRAK2 ARHGAP9 MBD2 MARK3 CMTM6 NCOA1 HCK MTPN NCKAP1L CREBRF FMNL2 LIMD1 HRH1 GLUD1 EPC1 FBXO11 WNT11 PIK3AP1 SPOP FPR2 CD86 GNB4 STX12 PGGT1B IST1 BMP2K ITPRIPL2 RTN1 ATP9B TRAPPC8 TBC1D1 ABI3 ITCH RPL18A IQGAP1 EIF4A2 UBAP1 HERPUD1 CDC14A CX3CR1 FHOD1 ESCO1 FCRLA TES GLIS2 PIP5K1C ABCA3 USP45 IRX5 JARID2 GPATCH2L ANKH EIF4E3 IVNS1ABP MFHAS1 PPFIBP2 PYCARD FEM1C TAOK3 RNF145 TMEM127 ACRBP APBB3 MYO9B	down	**
GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP	0.0020287	0.0117443	0.4317077	0.3467432	1.553259	169	DDX11 GPT ZMYND8 KIF18B DEPDC1B COL7A1 PLK1 KNOP1 RAD54B KCNMB4 TNC NOS1AP RPAP1 COPG2 CENPL VANGL1 NEB CENPO RAD51AP1 ANKRD16 CXCL9 CCDC136 STXBP4 ZNF512B ANAPC5 FAT1 PICK1 TNK2 STAT2 DPH7 SF3B3 IGSF3 HMGXB3 ZNF692 TBX1 ARFRP1 BCL2L12 KDM3B NRF1 BAZ2A RNF187 STRN4 CKAP5 CENPM FITM2 SRRT TIAM2 CHTF8 KIF21B RNF215	up	*
GSE3982_MAST_CELL_VS_TH2_DN	0.0008350	0.0058292	0.4772708	0.3455808	1.553052	176	RIBC2 TRIP13 FOXM1 GPT CDC45 GABRB3 TIMELESS PLK1 SFXN1 CDC25A MIS18A MYL6B COQ3 AURKA TPR RSRC1 MCM3 LMNB1 LIG1 ORC6 DCTPP1 INPP4B BLM SLC25A10 CKS1B APLP1 DDX51 BIRC5 GMNN GOLGA8A MRPS2 PDK1 SPAG5 FADD ETFB PA2G4 MRPL11 SSRP1 KIF20B IGHM POLD1 NUP85 DGKA RPA1 TDP1 URB1 ATAD2 CEP152 TCERG1 MSH2 GBP1 USP39 PPP6R2 PAXIP1 ETHE1 ADRM1	up	**
GSE22886_IL2_VS_IL15_STIM_NKCELL_UP	0.0040406	0.0204333	0.4070179	0.3565202	1.552547	133	ATP6V0A4 PTPRZ1 EGLN3 ASB4 DGCR9 GUCY2C ABCA12 PCDHGB6 SEC14L5 THTPA SGK2 INSRR SCG5 ITGB4 HAVCR1 WDR78 SYT2 MCCC2 B3GNT3 SCAMP5 BACE2 PSRC1 RNF216 DCLK1 ZNF480 KIAA0556 ING4 ESRP1 KCNJ14 RAPGEF5 IGLV6-57 ADAM12 FMO6P COL5A2 TPO SPTBN5 OS9 TYRO3 PTN KCNB1 TFCP2L1 TIAM2 C1orf56 RAB3D MMP24 FSCN2 PMS2P1 ME1 FKBP9 MAP3K9 RARRES1	up	*
GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN	0.0017239	0.0103248	0.4550599	0.3507633	1.552132	151	TRNP1 NPAS1 PPP1R14D CABIN1 CA12 DPYS C6orf132 NEURL2 BPIFB1 FAM171A2 MAD1L1 HEBP2 MARK1 CXCL11 GPX8 CBX5 GOT2 AP5Z1 COA4 RNF207 SEMA4F ITGA2B EFTUD2 MZT2B MLF2 NGFR MRPL11 SALL4 TK1 SPTBN2 USP43 FHL2 IQCH NAGS ZNF428 ZNF558 CCSER1 LRIG1 OVOL2 LSM4 NEFH EIF3K CAPN10 R3HDM4 FOXD2 BCL6 POLR1A COPZ2 NUP210 RABL6 PPP1R14B MOK SLC1A7 NELL2 KCNK6 RPUSD3 GLIPR1L1 PAQR8 PRSS50 HRAS	up	*
GSE45365_WT_VS_IFNAR_KO_CD11B_DC_UP	0.0018223	0.0107745	0.4550599	0.3497453	1.551405	156	UNC5CL STYK1 THEM4 CABIN1 NIPSNAP1 MSTO1 EIF3B ACY1 LIME1 AARS2 ANO9 RPL39L LINC00954 KLHDC4 ANKEF1 SBK1 SMYD5 MTG1 ALG3 HPS4 PPIL2 DDX51 TNFRSF25 JAKMIP1 TCF20 CMTR1 GNPNAT1 PEG10 NOP2 ZNF827 FAM102A GIPC1 PELP1 YDJC TRMU LMF1 KRI1 NAT9 L3MBTL2 C12orf65 UTP20 NOSIP SURF2 WDR35 CLUH ANXA2P1 ANK3 GLO1 MAP3K14 MRPS25 TYSND1 SOX12	up	*
GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_UP	0.0041330	0.0208175	0.4070179	0.3562546	1.551390	133	SLC26A4 PTPRT ACY3 APOLD1 TRIM17 CHCHD6 CHST4 PIF1 NIPSNAP1 SEC14L5 KCNT1 XDH LRRC27 NLE1 MYBPC2 GPR182 ANKRD52 ASPHD1 WDR73 EEPD1 WDR31 TMEM231 TSPAN1 MYO19 RABL2A ACBD4 POMT2 CEP128 ENPP2 CLTB ABCC9 RABEPK CH25H ANK3 MED27 CNTN2 CAP2 TMEM141 INO80E MTIF3 PPP6R2 KIAA0825 F13A1 ALKBH6 PGPEP1 CELSR3 KRT80 FUT10 PARP2 GLIPR1L1 POLRMT DRG1 ITGB5 FAM110C	up	*
GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP	0.0010276	0.0068770	0.4550599	-0.2947296	-1.551195	169	SOSTDC1 GLIPR2 F2RL3 SNX10 CD9 TMX4 PDE2A RBM7 PTS RAPGEF4 LATS2 GM2A RAB33B ADRB2 FBXO8 FLI1 EVI2B ARRB1 AHNAK PPM1K ATL3 COTL1 CAPZA2 KLRD1 HLA-DQA1 CRIM1 C16orf54 EMP3 NSMAF EBAG9 SOCS3 PLEKHA3 LIMD1 PDE5A FOXN2 GMFG GPR183 GRASP RTN4R LPCAT2 TBX21 PELI1 PNPLA2 NKG7 IRF5 GPR18 SERINC3 SELPLG SESN1 C3orf38 RIPK2 GPD1L SCPEP1 TTC32	down	**
GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_UP	0.0007723	0.0054790	0.4772708	0.3456572	1.550559	173	BDH1 BUB1B POLE ASPM DGCR8 CCT6A RCCD1 MRPS35 FAM220A AP4M1 GTPBP3 WIPI2 PRKDC RAD54L TOPBP1 CHEK1 TIMM50 RAD18 IPO9 SLC28A2 PHB IDH2 STXBP4 GCKR ZNF32 KIAA0753 ANKRD54 ACP6 MECR KXD1 RNASEH2A SNRNP25 MZT2B GNPAT FANCF AARSD1 LRRC8D LMF1 METTL22 PKP4 CCDC51 SASS6 PRODH DNAJC21 POLR2I SLC1A5 RRP36 TCHP CBR1 BANF1 SNRPD2 CSNK1G2 WDR77 HOOK2 SNX7 MLLT1 ATG2A SMC2 MAPK8IP3 SWI5 SMPD4 DNAJC10 ZMAT2 PGPEP1 FRMD6 TRUB1 SLC35G1 RRS1 CALU BCKDK RCN2 LUC7L3	up	**
GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP	0.0013225	0.0085006	0.4550599	0.3443386	1.550420	180	HELLS CDC45 BUB1B NEK2 UBE2T TTF2 SRGAP3 CDCA2 NIPSNAP1 POLE STIL ESPL1 CDC6 TPX2 MCM4 ARHGAP33 TYMS AP1G2 HOMER3 DPY19L1 AURKA LARS2 RAD54L LMNB1 CENPO RAD51AP1 DCTPP1 KHK HES6 SPC24 ZCRB1 KNSTRN HPS4 IQCB1 CENPH PACS1 TNNI2 SSX2IP SNCAIP DNMT1 SLC35C2 CENPQ ATAD5 NFXL1 PALB2 OLFML3 CENPT SH3BP5L NEDD8 STK35 GLIS3 PRIM1 TRIP6 PFKM ARHGAP11A OXCT1 LBX2 TNS3 CPT1C KIAA1522 PPIA GPN1 CCDC91 ZNF367 KIF24 APOBEC3B APEH SLC38A10 FURIN BCL7A FASTKD3 ZNF579 TMEM9 HSD17B7 MMP14 LRP8 MAP3K5 LOX	up	**
GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP	0.0008522	0.0059144	0.4772708	0.3457213	1.549634	170	FOXM1 POM121L9P CDC45 FANCI CHEK2 BUB1B NEK2 FAM153B PRIM2 BRCA1 IRS1 TTK SLC27A2 KIF14 SPP1 STIL ESPL1 COCH CCNF MELK RPL39L DPY19L2P2 WASF1 BUB1 FANCA DPY19L1 RRM2 CDC25C RAD51AP1 BLM RGS4 MGLL CDKN2C DNA2 SPAG5 RAPGEF5 NRGN CCNE1 DLGAP5 AGL TRIM9 ANP32E KIF20B SPA17 POLD1 GNAZ CDC7 TADA3 RDH16	up	**
GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP	0.0003427	0.0027595	0.4984931	-0.2912817	-1.548660	180	SLC6A4 SWAP70 MS4A7 LY86 LONRF1 ALAS1 BCL2A1 NCF2 GALNT18 SLCO2A1 ANXA1 CLEC7A IFI30 LITAF CYB561A3 SERPINB9 GRN SFRP1 SRGN CST3 FABP5 DUSP3 CCL22 AHNAK GRK5 GMPR AXL FCER1G PLEK ACTG2 MYH11 HLA-DQA1 HEXB ATP6V0B HSPA1B STX7 CD83 IRF8 PSTPIP2 LPCAT2 OGFRL1 SERPINB1 TEC TSC22D1 CD86 GNB4 APLP2 LGALS3 DECR1 TAGLN DBNDD2 ICAM1 PARM1 CDC42EP3 ISCU S100A4 NRP2 GRB10 EHD4 RNH1 PAPSS2	down	**
GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_UP	0.0023147	0.0130827	0.4317077	0.3472116	1.548656	162	TRIP13 MCM10 IGF2BP3 MPP6 CPSF6 DEPDC1 RACGAP1 E2F8 GMPS AP1S1 CDC6 CCNB2 FIGNL1 KNOP1 MCM4 DTL EXO1 KIF23 DPY19L1 SAE1 ATR RRM2 AKAP1 KLHDC4 MCM3 CDC25C CCDC58 BRI3BP THYN1 MAD2L1 AHCY TIMM50 SPC24 BRIP1 CENPH BIRC5 CENPP PA2G4 TACC3 SNRPA ARL6IP4 GALNT3 ATAD5 COX10 CDC7 PPP1R8 UTP20 SNRPD1 LTV1 SLC35A3 PRMT5 BANF1 RAD51 COX5B WDR76 PGAM1 CLNK DDX52 ZBTB32	up	*
GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN	0.0007852	0.0055280	0.4772708	-0.2991815	-1.548471	149	IL1A FCN1 TRHDE IL1B F2RL3 GREM2 PTPRE CDC42EP2 CDC42 PDE4C PILRA RHOA BTG2 MCL1 MYOZ3 MAP2K3 CASKIN2 HAUS2 PLBD1 HPSE KCTD20 TLR4 PRF1 WASF3 OXSR1 CA1 TAF13 EMP3 HECA MTMR14 ETS1 PPP1R15A TNFRSF9 RASSF2 ZNF407 BIN2 MME EHD1 JMJD6 TESK2 FPR2 TERF2IP RGS2 CES3 IQSEC1 CYB5R4 KCNJ9 SYNPO2L FLT4 SETX FHL5 CHIC2 AKTIP OSGIN2	down	**
GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN	0.0003176	0.0025748	0.4984931	-0.2930773	-1.548149	174	IL1A MS4A7 CCRL2 CD300E CD9 LAMP1 IER2 NFIX PTPRM BTG2 CYYR1 LITAF NR4A1 SPRY2 PDE4D LRP4 GPR4 IL10 KLF4 PLAUR ID3 ZFAND5 CCL3 ATF3 PER1 DUSP1 CD300C MAFF LACC1 SLC25A33 SLC25A25 IL6 MED28 ADAMTSL2 JUN OXNAD1 PLK3 JUNB RCAN1 PTGER4 ACKR3 FOS SPRY4 PKD2 FOSB EHD1 DUSP5 NFYC PLEKHO2 PLA2G15 FAM98B GTF2B HSPA2	down	**
GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN	0.0005036	0.0038091	0.4772708	-0.2913765	-1.547729	177	CD101 BAIAP2 TGFBR3 NEDD9 TRIB1 RFTN1 ARSB ENTPD1 BTG2 ZYG11B PPP3CC CCNI RHOB PIP5K1B MVB12B TJP1 CLIC4 FMNL3 DOCK9 CDKN1A ATF3 CCL4 RBPJ RNF149 CREM JUN HPGDS PPP1R15A PTGER4 SKIL TIGIT SNX9 SLC3A2 ATP6V0D1 MFSD10 PIK3AP1 EHD1 CD86 PDCD1 APLP2 GABARAPL1 RGS2 PDE4B ETS2 ICAM1 IER5 TOB2 ITGAE NUP98 NFKBIA GPR171 SLC16A10 HERPUD1 EGR1 PRKCH ICOS ZFP36 QSOX1 CYP51A1 DNAJB1 SPTY2D1 ARHGEF12 FNDC3A ATP2B4 NFIL3 SIRT1 NR4A3 IRF4 DUSP2 ZFP1 ADAM19 TNFRSF1B	down	**
GSE4590_SMALL_VS_LARGE_PRE_BCELL_UP	0.0008889	0.0060911	0.4772708	-0.2952873	-1.547288	165	DAB1 GCOM1 MS4A7 GAPT ZC3H12C CYP4B1 HCAR2 NEDD4L SLC15A3 CD8A ZEB2 PLA2G7 IFI30 LAIR1 C1orf162 RB1 SLC25A37 CD93 PDE4D FBXL5 TBC1D9 SPNS3 PTAFR PXDC1 VASP CCL3 ERP44 CCDC38 CXCL2 C9orf72 HPSE PRF1 EPS15 HCK ATP6V0B TYROBP TMPRSS11D PTGER4 ACKR3 LUZP2 NKG7 PIK3AP1 VPREB3 DUSP5 NAB1 PHF19 RGS2 IL18 LAT	down	**
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN	0.0006883	0.0049550	0.4772708	-0.2948677	-1.547168	161	ABHD5 ASGR1 MIR22HG HSD17B6 SLC6A12 EGR2 BACH1 EML1 BCL2A1 NCF2 IL1RN FAM49A SYNC SIGLEC6 LRRFIP2 ADIPOR1 RGCC ATP6V1H ATP6V1B2 KIAA0513 PTAFR CLIC4 SPAG9 ATF3 CDS2 B9D2 DCHS1 CLN8 RPS6KA2 PGD ETV3 SH3BP5 KLHL18 PSTPIP2 HOMER1 RNF24 RALB TAGLN2 TIMP2 SAV1 TGIF1 TSC22D1 CD86 KYNU VPS39 ELOVL1 IQSEC1 ALDH2 GLRX2 CAMSAP2 DOCK4 NRG1 GREM1 C5AR2 DUSP6 EXPH5 TMEM43	down	**
GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN	0.0014115	0.0088845	0.4550599	0.3443891	1.547105	171	HMGA2 MDM1 GMDS GABRP DEPTOR NEK2 CCDC34 TIMELESS PRIM2 DEPDC1 CDCA2 RACGAP1 C4orf19 RAD54B TYMS EME1 POLA2 ICA1 BRI3BP CKAP2L FADS2 ASF1B RFWD3 EEPD1 GOT2 TMEM8B SSX2IP SPAG5 SRD5A1 KPNB1 DNMT1 AGL ESCO2 CLTA FUCA2 KIAA1549 CCDC137 CENPM NAT8L C16orf58 ZNF446 RAI14 CKAP2 BSN CCNA2 CDH1 HDLBP RNF157 ZWILCH SCOC SOX12 TBC1D32 RNF7 POLR1A SEPHS1	up	**
GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP	0.0008889	0.0060911	0.4772708	-0.2952420	-1.547051	165	HHEX LRRC8C HSD17B11 SH2D3C INPP5K P2RY13 FRAT1 RCHY1 PDE2A BEST1 TACC1 GNGT2 HLX PPP3CA RB1 CCDC82 PTPRO ID3 MARVELD1 PNRC1 LBH ELMSAN1 MYO1C PRKRA WASF2 HECA KCTD12 MSRB3 RASSF2 KLF2 WNT11 TFEB BAZ2B APLP2 ANKRD13A JUND UNC13D BNIP3L SESN1 CDC42EP3 SPIB TPT1 CD19 RNF38 CCND3 EVI5 IRF2 C1QB CNR2 C16orf95 RB1CC1 RNF167 MAP4K2 GPR137B RCSD1 SERP1 MAN1A1 FCRLA	down	**
GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP	0.0008096	0.0056756	0.4772708	-0.2950431	-1.547045	166	SMAD6 CXCL3 HMOX1 FABP4 BMP2 GTF2E2 AQP9 C5AR1 SLC11A1 ZBTB2 FGR KCNAB1 WWC2 SLC44A2 SH2B3 ENTPD1 PLXNA2 ITGA5 COX18 STOM RGCC SLC19A1 PPP3CC MSR1 MAP2K3 NES UBQLN1 CADM1 VIM HOPX IL7R PEF1 TANC1 PROCR NINJ1 PDK4 PHTF2 ESD RAB8B SLC35E4 INMT PLK3	down	**
GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP	0.0007331	0.0052297	0.4772708	-0.2946233	-1.546818	167	SLC12A6 PHACTR1 SPNS1 EGR2 PLEKHF2 BMPR2 GIMAP6 LAMP1 CD22 MTF1 FOXP1 HIPK3 CD93 LAMTOR3 ATP6V1B2 CST3 LRRC57 TCP11L2 MAP1LC3B ARNTL LAPTM5 N4BP2L1 CNOT6L NCOA1 CREBRF ELF1 SGK1 RHOBTB2 CPEB4 RAC2 ATP6V0B OSTM1 PTGER4 CCR7 IRF8 GMFG COBLL1 STX5 DOCK8 SNRK CELF2 ATP6V0C C8orf37 GPR18 ADAM10 TXNDC15 NT5C2 TMEM184B COMMD8 SNAP29 ANXA11 FCRL1 IRF2 EGR1 PXMP4 ITGAL FAM8A1	down	**
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP	0.0011032	0.0073129	0.4550599	-0.2938516	-1.546573	169	SEMA3G PTPRE SIK1 ELF2 YPEL5 RPL23AP53 ATF7IP2 TMX4 TXNIP ANXA1 DPEP2 GATA3 SLC7A2 MOAP1 CADM1 ZBTB43 DUSP1 ARL4A GNAQ MYH11 AFF1 PLCD1 NCOA1 SLC8A1 SGK1 AQP3 JUN PTGER4 THUMPD1 PREX2 TSPYL1 TNFRSF10B FOS KLF2 PTP4A1 XYLT1 FAM204A CBFA2T3 IRS2 FCGRT TOB1 RLF IQSEC1 USPL1 EPHA4 NLRP3 PTCH1 ACACB OSER1 RBM48 DNAJB9 P2RX1 RORA DAZAP2 NR3C2 PPP1CB SLC16A10 ARHGEF18 ATP6V0A1 NR4A2 ITGB1 FAM8A1 FPR1 CD69 DPF3 DNAJB1 LDB3	down	**
GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_UP	0.0028401	0.0152525	0.4317077	0.3486641	1.546465	155	PRIM2 DGCR8 RAD54B ZWINT TAMM41 GOLPH3L CASP2 TMEM41A TOP2A COASY ANKRD52 FAM162A SMYD5 IPO9 ALG3 SKP2 RNF216 CBX5 ASF1B POLE2 EZH2 MECR SF3B3 LIPT2 SNRPE HSPA4L MYO19 DNMT1 FANCG TELO2 THNSL1 DCAKD DPH2 AGPAT5 C12orf73 TADA3 PSMB3 MED24 TDP1 NDUFS7 RFC5 ICK WDR77 LPGAT1 MCU TARBP1 SMC2 POLR1B NMT1 RASGEF1A BCKDK PDXP MUS81 DHDDS APRT APBA3 NFE2L1 NPM1 TLCD1 ARFIP2 TRIM59 NDUFB2 TXN2 MTHFD2 POLD3 NUDT19 WDR12 SDHC KHSRP EIF4EBP1 GRWD1 AMPD2 NUP43	up	*
GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0005614	0.0041633	0.4772708	-0.2933720	-1.546417	172	ACP5 SPN FOLR1 CLYBL PLEKHA1 ELMO1 ZBTB2 FAM49A PPM1N TMX4 PDE2A CACNA2D2 LATS2 PPP1R15B NAAA GM2A NFE2L2 CRTAM HERC3 APOC1 FBXO8 FLI1 ARRB1 TCP11L2 STK17B CTSD ELAC1 DUSP11 MOB3A EFR3A EMP3 TMEM9B ELF1 PLEKHA3 LIMD1 OSBPL9 FOXN2 IDNK TAGLN2 RRAS MBP ICAM2 TEC GPR18 ME2 SELPLG MOB3B SESN1 SLC35D2 C3orf38 XKR8 SETD4 GIMAP5 RIPK2 TDRP GPD1L TTC32 RBM48 MAFK CNN2 MAN1C1 SETX HERPUD1	down	**
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_DN	0.0009393	0.0063474	0.4772708	-0.2951152	-1.546386	165	SIK1 AKAP7 HMGCR NR3C1 UBL3 NAAA PBX3 KLF10 KLF6 GRN TFRC KDSR ADARB1 MAP2K3 SDCBP SORBS1 NPNT TRIM46 ST3GAL2 UHRF1BP1L CDKN1A ATF3 HPSE ID2 CPT1A RBPJ SEC14L1 GLUD1 MALT1 LPCAT2 NIPSNAP3B YPEL2 CCR4 TEC IRS2 GALC RELL1 PIM1 ATXN1 GNB4 STX12 SPOCK2 PLA2G15 RTN4 FBXO30 TOB2 ARL14EP KIT DUSP7 EHD4 TRIM36 PMAIP1 RABGEF1 ATP6V0A1 HERPUD1 TMEM30A CCDC112 TMEM43 HMGCS1 YWHAB AKAP12 IL5 SLC43A3 ATP2B4 WDR26 DOCK5 EBI3 MYO1F FBXO33 ANXA6 IL10RA CAPG EZR ZC2HC1A TLN1 FARP1	down	**
GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN	0.0008096	0.0056756	0.4772708	-0.2949160	-1.546379	166	HSPA12B IL17RB BMP2 ARRDC4 BDNF STXBP6 KANK3 MANBA IL1RL1 PEAR1 SPCS3 EDEM1 KCNK3 ENTPD1 ZDHHC2 AHRR PBX3 PPP2R2A ANKRD29 EFCAB14 PER3 NRARP BST1 GAA ARNTL BCHE C9orf72 AXL HPSE ATP6V0D2 MBD2 N4BP1 UBASH3B PPIL4 METAP1 NDNF PNPLA8 PSTPIP2 WDR7 CCR4 TIMP2 EHD1 NIPA2	down	**
GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP	0.0005614	0.0041633	0.4772708	-0.2918865	-1.546274	175	TMEM100 TUBD1 GPR65 ST3GAL6 THAP2 MSRA LAMP1 CBL PPM1D DNASE1L3 CNST STARD4 TRAF6 CCNI KDSR CPED1 FOXO1 ACSL3 USP2 SCAF4 SPAG9 ERP44 HPSE CCSER2 ELMSAN1 MBD2 TBC1D4 NRBF2 HSDL2 MAPRE2 GLB1 MTPN EBAG9 HECA GABPA ETS1 PIK3R1 ZNF597 PPM1F CDK17 YPEL2 ZNF521 SAV1 BAZ2B VAMP4 KHDRBS1 ANKLE2 RNF138 SFT2D1 TRAPPC8 LTBP3 CECR2 ABCA8	down	**
GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP	0.0011032	0.0073129	0.4550599	-0.2937110	-1.545834	169	LIMS2 ACP5 PHACTR1 TRHDE FOLR1 CD44 IER2 PLA2G7 CACNA2D2 ENTPD1 MTF1 APOC1 TUBB6 TBC1D9 AHNAK PTPRO CASP1 REST PDE8A CXCL2 IGFBP2 CCND2 FCER1G HES1 HCK FLT1 IL6 TYROBP DNASE2 CCR7 IQSEC3 SKIL GPR183 POGLUT1 KLF2 TNFSF13 MBP FOXO3 GSAP TGIF1 CLEC2B CCR6 OPN3 SCN7A ICAM3 FNBP4 NFKBIA LTBP3 MT2A BANK1 LYZ	down	**
GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN	0.0002506	0.0021261	0.4984931	-0.2904503	-1.545743	184	HSD17B11 DDX6 NEDD4L AQP9 SRSF7 VAMP2 PLEKHA1 LAMP1 HSPE1 EIF1 EIF5 NLK ABCG1 KLF6 PRSS12 GATA3 RGCC ADRB2 RHOB ARRB1 KLF4 NR1D2 SELL PNRC1 CCND2 DUSP1 SMAD7 IL7R BTG1 RBM39 CTSS SOCS3 RNF141 DDX47 JUN NOTCH1 KCTD12 GSTO1 CCR7 PABPC4 DDX5 CD7 DYM DEDD SLC3A2 FOS MBP FOSB NR2C1 PIM1 TOB1 KANSL2 RGS2 ETS2 JUND SESN1 PCM1 TDRP TRAF1 RNF38 SKI MCOLN2	down	**
GSE14000_4H_VS_16H_LPS_DC_UP	0.0017348	0.0103452	0.4550599	-0.2966615	-1.544491	156	EPAS1 ZC3H12C LTA4H SAMHD1 RTN3 MSRA MKNK1 CBL SPCS3 DNASE1L3 CD33 BTG2 PARVG REV3L GPBAR1 GPM6A EFCAB14 SCP2 LIMS1 RRM2B KLF9 GAPVD1 PLEKHB2 HTT MPC1 UBASH3B ACTR2 ZNF426 TBC1D5 TECR FLT1 OASL SNX29 GLIPR1 ATP13A3 HOMER1 NIPA2 OSGIN1 TPMT ATXN1 MBNL1 RXRA ABL2 IQSEC1 RAB5A ESYT1 MEGF9 RPS13 S100A4 TMX2	down	*
GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN	0.0005931	0.0043479	0.4772708	-0.2928388	-1.543606	172	TAL1 OSBPL11 CLDND1 CLYBL NR3C1 PDCL SSTR1 RAB33B HIPK3 BFAR ASH2L CCNI PTPRO BNIP2 OSTF1 ZADH2 VRK2 NFKB1 CDKN1A ATF3 C9orf72 IGFBP2 PPP2R5A N4BP1 LMBRD1 EFR3A ZDHHC20 TDRD7 USP25 RPS6KA2 ETF1 TECR PDE6B PLEKHA3 MITF RAB31 USO1 PPP1R15A CST7 BLOC1S6 NKG7 NIPA2 TSC22D1 ATAD2B PDLIM5 SERTAD1 CHMP3 TIAM1 NFKBIA ZDHHC5 KLRK1 TNFSF9 IRF2 UBAP1 UBXN8 CHIC2 ZNF106 ENDOD1 DRAM2 PLEKHA2 CCNT2 XRN2 C6orf62 UBE2N POLR2B STARD5	down	**
GSE36826_WT_VS_IL1R_KO_SKIN_UP	0.0007459	0.0053051	0.4772708	-0.2939432	-1.543247	167	ACP5 FABP4 CYP27A1 HSD17B11 CRY2 CLEC10A DPEP2 NAAA ABCG1 SLC7A11 APOC1 CST3 EPB41L2 FLI1 CYBRD1 CFD PER3 SRSF5 KCNMA1 CPVL CTSD ITGAX WDR48 CLIP4 HLA-DQA1 PI4K2A VWF STK24 BTBD18 MYLIP BCAR3 CTSS MITF DNASE2 PABPC4 COBLL1 RNF146 FOXO3 TCF4 CD86 IRS2 HBP1 CD81 RGS2 CLEC2B SEMA4A CEBPD TPT1 CXCR4 CDKN1C ISCU LTBP3 LYZ ZBTB40 CBX7 ACSM5 BHLHE41	down	**
GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP	0.0013224	0.0085006	0.4550599	-0.2943898	-1.542894	159	FIG4 OTUD1 MYADM VAT1L BMPR2 LINC00622 MANBA NEDD9 FRAT1 ABCB1 SWT1 BTG2 SERINC1 PICALM HDC LCP1 CLK1 PTPN21 OSTF1 DUSP1 ACTG2 CLIP4 RUFY3 SPIN1 ARL6IP5 CPAMD8 CREM PSEN1 CYB5R1 MTMR9 ZNF540 PIK3R1 GRB2 FSD1L FSTL3 RALB XYLT1 TSC22D1 HBP1 CCDC68 EXOC1 CLASP2 LTBP1 TAGLN BNIP3L CTTNBP2NL ITPRIPL2 LMOD1 RTN1 CEBPD TRAPPC8 MMD FAM13B EHD3 RAB2A REEP1 VPS13D TMEM30A CLIP1 PRKCH ITGB1 DYNC1I2 COX20 WDR47 KIDINS220	down	**
GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_DN	0.0074634	0.0333097	0.4070179	0.3703672	1.542813	96	MNX1 GRIA4 GALNT14 CUZD1 PAX9 C5orf46 C12orf40 ANKRD22 FBXL19-AS1 ASXL3 CDT1 ANKUB1 SLC34A3 PCDHGA3 SYT2 MCM3 CLIP3 KCNJ11 FBXO16 TMEM106C LRRN2 VN1R1 SRCIN1 SEC61G KSR2 TMEM79 ABCA4 VBP1	up	*
GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP	0.0005421	0.0040387	0.4772708	-0.2901095	-1.541000	177	ADPRH CPEB2 LPXN KIAA1109 MYD88 GNPTAB ZBTB2 ABCB1 CSRP1 COX18 KLF6 M1AP ABHD6 PPP2R2A ARHGEF2 TXN CST3 SLC7A8 CLIC4 CDKN1A NR1D2 PNRC1 WDR48 INSL6 KREMEN1 PIAS1 ST6GALNAC6 USP25 SGK1 PPP1R15A CCR7 MORC3 HOMER1 OGFRL1 TAGLN2 TPRA1 POGLUT1 CD164 ICAM2 MARC2 SPOP STXBP3 MTMR2 HBP1 ACYP2 NR2E3 PDLIM5 SERTAD1 NSUN4 TRAF1 FNBP4 SIN3A NFKBIA THRAP3 CYTH1 AIM2 EHD4 CNN2 BMI1 JDP2 SERPINE1 TNFSF8 TMEM30A NR4A2 ENDOD1 CRBN	down	**
GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN	0.0004944	0.0037579	0.4772708	-0.2922324	-1.540842	173	CD300LF SIDT2 SWAP70 PECAM1 HSD17B11 CALCRL VAMP2 NR3C1 ZBTB2 FAM49A HPS5 PDE2A ATP2B1 UBL3 GNGT2 RNF125 CSGALNACT2 FOXP1 GLS MAFG KLF7 ELMSAN1 IL7R PIAS1 FOXN3 SRF RNF141 NXF1 NECAP1 VAT1 JUNB CCR7 RC3H1 TMEM167B ACSL1 AZI2 TFEB ZBTB11 DYNC1LI1 ATAD2B INO80D SF1 SSH2 ARPC5 SKI CYTH1 FAM13B BANK1 SPATA13 CDC14A ENDOD1 LNPEP CLOCK ITGAL	down	**
GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_UP	0.0011915	0.0077920	0.4550599	-0.2926521	-1.540260	169	CPEB2 SNX10 GPR65 PTPRE RUNDC3B ARRDC4 CALCRL BMPR2 SLC39A8 STX11 ANXA1 CYP17A1 RNF182 AHNAK AIRN LEPROTL1 DRAM1 TJP1 TMBIM1 PDE3B VIM HOPX ID2 ARHGAP9 FRMD4A PRF1 ELK3 ADIPOR2 PDE1C NRBF2 ADD1 CNOT6L EMP3 MED28 MED30 ATP11A JAK1 GLIPR1 RPS6KA1 TSHZ3 TIMP2 GLRA1 POLK RXRA RBL2 YAF2 ELOVL1 ATP9B ORMDL1 ITGAE MBD5 KIT FNIP2 MMD GIMAP4	down	**
GSE3982_MAC_VS_TH1_DN	0.0027709	0.0149334	0.4317077	0.3438211	1.540169	169	PRB3 TIMELESS DGCR8 ALDH18A1 GPI SFXN1 TFDP2 KLHDC8A PRC1 XRCC2 ORC1 GINS4 HMMR KIF23 F2RL1 KNTC1 PAFAH1B3 NUP155 ODF2 CLSPN TFR2 EIF2AK1 KDELR2 PERP PKMYT1 ERCC2 NCAPG2 NUSAP1 ASF1B DNAH6 BIRC5 GOLGA8A RBCK1 TRAF5 DNAJC7 DNAJA3 SNRPA DUSP12 TK1 STOML1 CSNK1G1 NR6A1 TSTA3 DGKA PPP1R8 CDR2	up	*
GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN	0.0010595	0.0070808	0.4550599	-0.2977202	-1.539959	150	SLPI SASH1 ABHD5 ENDOU IL1B MNDA DCSTAMP ARHGEF15 AATK AQP9 P2RY13 BCL2A1 IGSF6 LITAF SLC7A11 LHX6 TNS1 ATP6V1B2 SDCBP MEFV BST1 DRAM1 STX3 DENND3 PLBD1 LY96 ITIH5 P2RY2 CTBS TLR4 ARAP3 GCA LMBRD1 HCAR3 RNF141 TREM1 IFNGR1 APH1B RALB CDK14 DGKG MME TFEB SOD2 STON1 NRN1 FGF2 XKR8 CYB5R4 MEGF9 STAM2 MARC1 ARPC5	down	**
GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN	0.0007204	0.0051538	0.4772708	-0.2920028	-1.539199	172	SLC31A2 DENND5A MYD88 STX11 EDEM1 ATP2B1 ADA TNIP3 SERPINB9 PPP2R2A UBE2D3 PDGFA ATP10A PPM1K GMPR CDKN1A CCSER2 N4BP1 IL7R TDRD7 SRGAP2C DCP1A HESX1 IL6 PSEN1 SOCS3 MAML2 RAB8B STAT4 ELOVL7 IQSEC3 FSD1L RNF24 DENND4A GFPT2 PELI1 HIVEP2 ADPRM SAV1 AKIRIN2 TEX30 DUSP5 SOD2 ICAM1 RNF138 C3orf38 TNFAIP8 NBN IER5 LRP12 TRAF1 NFKBIA MCOLN2 TNFSF9 SSB OSGIN2 ASH1L-AS1 LAMP3 FAM160B1 WNT5A NMI IRF1 PTGS2 NCOA7 MSC EBI3 RNF19B SLC25A28 CDC42EP4 IL10RA FEM1C SLC5A10	down	**
GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP	0.0005259	0.0039538	0.4772708	-0.2898356	-1.538348	178	SMAD6 KRT81 SECISBP2L LPXN LIPA MYADM PAFAH1B2 SEMA6D KLHL30 B3GNT5 AKT3 EPB41L2 KIF1C MPEG1 NOSTRIN CASP1 KLF4 FAM76A MVB12B LAPTM5 NFKB1 CTBS C9orf72 ID2 MBD2 MATN2 PAFAH1B1 PIK3R5 DCHS1 MTPN PKIG RBPJ HESX1 NEK7 RNF141 CRNKL1 PDCD6IP ARL6IP6 SH3BP5 MN1 MSRB3 JUNB GPR183 HIVEP2 STX12 ATAD2B ANKLE2 EGFL7 OPN3 DDX59 SSH2 TMEM109 TLK2 CAMSAP2 NABP1 PURB BANK1 EIF4G2 ACVR1C CHML	down	**
GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP	0.0006708	0.0048636	0.4772708	-0.2927996	-1.537708	164	GPD1 OLR1 USP12 IL1B PTP4A2 SLC39A8 MAL SLC11A1 CD8A HSPE1 WNT2B LITAF STOM CLK1 BTG3 TXN TRPC2 CFD HNRNPA3 SOCS2 CCL3 NFKB1 SELL INHBA KLRD1 MBD2 N4BP1 PTGIS CRIM1 BTG1 NINJ1 IL6 KLRB1 STAT4 PPP1R15A WTAP CCR7 HERC2P3 ENTPD4 DENND4A CELF2 FOXO3 PPP2CB EHD1 CCP110 PIM1 SOD2 ANKRD12 ICAM1 BNIP3L CXCR4 TOB2	down	**
GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_UP	0.0011828	0.0077454	0.4550599	-0.2936041	-1.537540	157	EREG PRX NEDD4L STX11 OTUD4 MCTP1 MASP1 TNIP3 MAP3K8 RNF144B IL18R1 MAP2K3 CSRNP1 STAT5A BIRC2 SORBS1 CCL4 PLEK IL7R PIK3R5 SNN TDRD7 NINJ1 DDX60L IL6 OASL NXF1 MAP4K4 PLK3 PPP1R15A WTAP SKIL CD83 PI4K2B GPR183 PTGER2 PELI1 FXYD6 EHD1 SERPINB1 DUSP5 ARAP2 ANKLE2 C3orf38 IL18RAP MIR155HG EGFL7 RIPK2 ADORA2A AIM2 EHD4 PIM3 RBMXL1 SERPINE1	down	**
GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_DN	0.0009135	0.0062071	0.4772708	0.3423223	1.537459	175	CA9 TICRR DEPTOR UBE2T PSPH PBK TTK DGCR8 IFT27 CDC6 ACY1 CCT6A SDHA NUP155 MCM7 WDR78 MMS22L AKAP1 AMACR CHAF1B ORC6 CKAP2L RAD51AP1 SLC25A39 BLM GRHL2 MTG1 PPP5C DET1 CLDN15 FAM221A NPM3 SMO ILF2 CDC23 CNOT2 UROS LRRC8D GAS2 KIF20B CCDC51 CNDP2 SULT1B1 SASS6 DUS1L MUSK PATZ1 SPAG4 FARSA DDX54 RTEL1 MCU F13A1 WDR76 DNAJC10 FRMD6 SLC35G1 HGF CYP11A1 PCGF6 DLEU7 F5 TOMM7 METTL18 WDR55 PRRC1 PEX11A LCMT1 MRPL2 TIMM10 DUS3L GLRX5 TCN2 DHRS4 KLHL12 NAE1 NUDCD1 MTHFD2 QSOX2	up	**
GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP	0.0015599	0.0095783	0.4550599	0.3442888	1.537039	164	FOXM1 KCNK5 CDC45 POLQ CLGN KIF14 PMS2P5 TPX2 SLC35E3 MIS18A NCAPD2 SPDL1 CLDN1 STAG3 NUP155 VANGL1 KIF2C MPHOSPH9 GPSM2 SOX4 POLR3C KCNJ2 CKS1B NCAPG2 CBX5 HDGF C1orf112 ATIC AAGAB AP5Z1 FEN1 METTL3 SNRPE FOCAD RNASEH2A ULK1 GOLGA3 INTS7 NINL KIF22 SSRP1 ITFG2 PPME1 DHTKD1 PELO KRT8 TXNL4A CORO2A C1QTNF3 CCNA2 SMARCA4 RNF121	up	**
GSE18893_TCONV_VS_TREG_2H_CULTURE_DN	0.0004863	0.0037075	0.4984931	-0.2892746	-1.536820	179	LPIN2 ADPRH ARRDC4 SUSD2 GPCPD1 INPP5A AGPAT4 TGFBR2 SERPINB9 NFE2L2 CRK RAB14 IL10 NRARP RAB12 ITPK1 MGAT4A CDKN1A VIM CTBS ID2 PIK3C2A ARL4A RAP1GDS1 WFS1 MARK3 MYO1C VAMP3 SGK1 SOCS3 SNX2 CCR7 TBX21 CGGBP1 SNX9 RRAS PNPLA2 RUNX3 DAGLA STXBP3 EHD1 FEM1B CYGB STX12 GPR18 KAT2B ICAM1 ARAP2 G3BP2 CTSC NABP1 CYBA CRTAP CFL2 SLC19A2 DCUN1D3 SH3GLB1 NCF1 PLEKHA2 PCMT1 MAN1A1 IRF1 FNDC3A RAB1A	down	**
GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_UP	0.0022263	0.0126709	0.4317077	0.3470145	1.535544	151	HJURP NEK2 DROSHA PDCD2L NOVA1 PHF14 ZFP62 ZNF285 UMPS HNF4G ZNF850 CCDC13 ZNF485 RIPK4 RGS4 GUCY1B2 PSRC1 FRMD5 ZNF45 ZNF260 NAV2 TTI1 TNRC18 NAPEPLD ACVR1B PARS2 FANCF WDR53 ZNF234 ZNF544 GEMIN5 CCDC51 NAIF1 RMND5B SASS6 EFCAB7 CKMT2 NMNAT1 HAUS6 ZSCAN32 URB1 ZBTB9 RSPH4A INTS8 CEP85 NCDN PRIM1 DZIP3 ZNF70 RUNDC1 SLC35B3 ZSCAN29 SYNE2 MRPS26 PLXNB1 CSTF1 PAQR8 ZNF319 MLH3	up	*
GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP	0.0029801	0.0158588	0.4317077	0.3459567	1.535409	159	KLC3 LAD1 CHEK2 BUB1B TRIM17 NOVA1 PLEKHH1 TBRG4 GMPS BCAS1 EFNA5 KCNJ8 XPO5 TMEM81 DZANK1 HAUS5 TSGA10 TPBG CCDC77 GPSM2 PDZK1IP1 ASS1 PES1 PSRC1 KNSTRN PLOD2 AP5Z1 TRAPPC12 FOCAD LZTR1 ZNF354A SCLY PKP3 OSBPL3 FBXO4 COG4 SEC14L2 ABCC3 NOC4L USP21 FARSA ZNF622 CCNA2 CDH1 DTNB VPS33B ANK2 TNKS1BP1 ARHGAP5 MROH1 RHOT2 TBC1D32 ARHGEF39 POLR1B ZSCAN29 C1orf159 GGCX KHNYN ZFPM1 TIPRL LASP1 ZKSCAN4 MECOM DUS3L LZTS2 RNF40 ARMC6 IGDCC4 NDRG1 CNTNAP2 TMEM181 WDR25 FIBP IPO4 SLCO4C1 TTC3	up	*
GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN	0.0005935	0.0043479	0.4772708	-0.2889484	-1.534832	177	SIDT2 DENND5A KLF13 CALCRL MKNK1 NR3C1 GIMAP6 CBL FAM49A NUMB ANXA1 UBL3 CHMP1B EIF1 RAB33B RNF125 GLS HNRNPDL IL10 MAFG FAM49B NFKB1 RBMS1 CLK4 PAFAH1B1 AFF1 CRIM1 CDKN2AIP TAF13 FOXN3 VAMP3 VPS37A SAR1A PIKFYVE NXF1 NECAP1 SF3B1 KCTD12 N4BP3 REL NDST1 AZI2 TFEB CDC37L1 VPS39 PCM1 SF1 SFT2D1 IQSEC1 FBXO30 CREBBP SSH2 NHLRC3 SKI TTC19 FAM13B NIPSNAP3A CDKN1B DUSP6 ENDOD1 CDC42BPB ATP1B1 RNF167 SRSF11	down	**
GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN	0.0013225	0.0085006	0.4550599	0.3410956	1.532895	176	DDIT4 PRIM2 BRCA1 RACGAP1 ANLN NDUFS6 IFT27 CENPA ACAD9 ACOT8 CCNB2 XDH TAMM41 CISD1 KIF23 MKI67 F2RL1 PAFAH1B3 BUB1 TOP2A AURKA LMNB1 FAM162A MAD2L1 CNPY2 CKS1B NUSAP1 CDK1 BIRC5 GMNN POLR3K TRIM41 TSPAN31 EZH2 SNRNP25 DNMT1 ACBD6 ELMOD3 TUBG1 TACC3 MNS1 SLC37A4 TRIM37 HIP1R LCLAT1 POLB RAD50 CENPK CKAP5 CDC20 CKAP2 PDIA4 UNC119B RFC5 HK2 TRAK1 PGAM1 RPN1 DDX52 DTD2 LXN NCAPH CYB5B RNF14 UNC119 RCN2 LUC7L3 PLK4 CYTH3 RBL1 TMEM229B TMPO PTGR1 CCDC6 MLLT3	up	**
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP	0.0023260	0.0131170	0.4317077	0.3436678	1.532445	163	LTF ZDHHC4 CHODL SLC5A1 SAYSD1 C4orf19 ACY1 SPDL1 ZNF862 PCCB KNTC1 P4HTM MCM3 MCCC2 THYN1 TBC1D8 RABEP2 REPIN1 BLM SLC35E2B NAA40 TNIK TMED3 FASTK UCK2 ATIC KCTD13 TRAPPC12 NRGN G6PC3 DNAJA3 UROS PIGG PPOX SCNN1G TCEA2 KDELR3 MRPS33 USP21 HAX1 MMP24 POLR2I CCNG1 HAUS4 ENOX1 SPON2 PRIM1 SCNM1 TTC31 WDR77 TRAPPC9 RSAD1 DHRS3 MRPL48 ACAD8 MAP2K2 NCAPH CLNS1A INPPL1 SHQ1 CXorf40A AXIN1 TRAFD1	up	*
GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP	0.0010973	0.0072989	0.4550599	0.3418393	1.532233	170	NOVA1 STK36 ANKZF1 GMPS DGCR8 TFDP2 EXOC3 MIS18A CCDC77 RFXANK ZNF174 SETDB1 ZNF226 IFT172 SLC25A39 TRMT2A PRMT6 NCAPG2 KIAA0556 EEPD1 LRRC37A2 NRGN EFTUD2 INTS7 CNOT2 FOXRED1 TACC3 DHRS4-AS1 PLEKHG7 MTA3 LRRC8D CCDC159 NADSYN1 NIF3L1 CCDC137 NAGS FAM50B PPP1R3D MRPL41 MCM5 WDR35 LANCL2 PYGO2 PRKD2 MVP ZNF519 COG5 RRNAD1 RBM42 ZNF436 COX5B RNF123 PFKM RHOT2 ADRM1 LXN APEH TOP3A TYK2 SLC2A4RG PRCC KCNK1 SHKBP1 XRCC5 DHX38 MEN1 BBS12 GLCE MSH3 TTC38 PRRG4 BUB3 RALGAPA2 CHCHD5 RABGGTA SUSD3 TXK USP32P2 EMC10 RALGAPB	up	**
GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP	0.0005774	0.0042577	0.4772708	-0.2904794	-1.531599	173	LRRC8C MYADM RTN3 INPP5A C8orf58 TSHZ1 PEAR1 TXNIP SLC36A4 TTL CYB5A ANXA5 RB1 MCL1 ZMIZ1 AGO4 AHNAK FOXO1 TCP11L2 PXDC1 SOCS5 KLF7 ADD1 MAPRE2 AFF3 NCOA1 ZDHHC20 HEXB FRY WASF2 C20orf194 RAB31 KCTD12 PTGER4 CD83 GTDC1 SLC25A24 TESK2 SBF2 HBP1 ADAM10 SLC35D2 TXNDC15 ARHGAP18 MEGF9 LYST ANO6 SLC16A10 GJC1 SLC19A2 ING1 SLC38A2 FAM8A1 KBTBD11 TUBA1A ATP1B1 MICAL1 SNX14 MTSS1 GPR137B	down	**
GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0021080	0.0120965	0.4317077	-0.3003688	-1.531496	138	NUP54 BACH1 GTF2E2 DENND2C TRIB1 CCNL1 RBM7 SDE2 CSRP1 HSPB1 KLF6 CD93 FAM76A MAFG UBQLN1 DPH3 CXCL2 USP44 MIR24-2 DEGS1 MIR17HG CNOT6L TAF13 BTG1 CAPN11 PLK3 TMEM251 TMEM167B TNFRSF10B PTP4A1 PHF19 MAGOH ZBTB25 TOB2 MEX3C SCPEP1 KPNA4 ADORA2A MAFK CAMSAP2 ATF4 DNAJA2 BHLHE41 CLEC4E PIP5KL1	down	*
GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN	0.0005972	0.0043689	0.4772708	-0.2884540	-1.530825	176	WEE1 SLC31A2 FCN1 CD55 CAT LMO2 RTN3 ANXA1 ASAP1 CYB5A SLC25A37 CLK1 CFD DENND3 CLIC4 SCAF4 SIK2 HOPX HPSE MBD2 PPP2R5A BCLAF1 RAB6A SACM1L EMP3 SERTAD2 TMEM251 IRF8 DDX5 REL UVRAG KLF2 AZI2 PKD2 PPP2CB CHPT1 GSAP SERPINB1 BAZ2B GALC LGALS3 THAP11 USPL1 ALDH2 SCPEP1 NFU1 RHOT1 CSF2RB HMGCS1 SSB CLOCK CMPK1 ANKS1A SNW1 HLA-DRB1 WAC DAPP1 WDR47 TSC22D2 TES SLC23A2 ECHDC3 RAB11FIP2 SECISBP2	down	**
GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP	0.0027526	0.0148679	0.4317077	0.3450176	1.530434	156	PDE11A CA9 HP DEPTOR NEK2 CENPF WFDC2 COL27A1 PHGDH CDK4 RACGAP1 TRAIP DIO2 PAK6 XRCC2 ALDOC TMEM41A SMARCC1 KIF23 STAG3 BUB1 MDFI CHAD ANKRD13B CHAF1B LMNB1 MCCC2 PDZK1IP1 ORC6 INCENP CBX5 HDGF E2F1 NCAPG GDAP1L1 DGCR6 MOV10 OR10AD1 CCL21 LMNB2 AARSD1 DNM1 SGSM3 C12orf73 ATAD5 RAD50 KRT8 CKAP2 ODF3B LSM7 RTKN GAD1 CHRNA5	up	*
GSE27786_CD8_TCELL_VS_NKCELL_DN	0.0005320	0.0039750	0.4772708	-0.2880245	-1.530179	179	FFAR4 P2RY1 MIR22HG HSD17B11 RTN3 AKAP7 CLEC10A MKNK1 NEDD9 NFIX TOR1AIP1 RB1 ARHGEF2 TMEM38B LRP4 PRKD3 KLF9 PLEKHM3 RIT1 C9orf72 AXL HPSE FRMD4A INHBA ADIPOR2 SLC6A6 ANXA3 VCPKMT VAMP3 WASF2 PHTF2 KIF13A OASL SERPINB8 ATP6V0B SNX2 ATXN1L MBNL2 PRKACA YWHAZ SNX9 SOD2 BRI3 ACADL ACYP2 GEM HSPA2 CPQ DCTN4 SPIB ARHGAP18 ALDH2 ACTB TMCC3 SPATA13 KLC1 ZNF326 CYBA CHP1 TMEM30A	down	**
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP	0.0010136	0.0067929	0.4550599	-0.2918167	-1.530127	166	SC5D PTPRB SIK1 HSD17B11 SAMHD1 CITED2 DPEP2 TNFRSF8 PTS PTPRM SLC7A7 ASAH1 NAAA PDE4D PPP3CC CDADC1 ITPRIP SGTB PSTK KLF11 TPP1 ST7L DUSP1 RNF139 UBASH3B MYH11 MAFF SNN TBC1D5 JUN OXNAD1 LIMD1 SNX29 ATXN1L SUGT1P3 FBXL16 SLC10A7 OGFRL1 TAGLN2 PTP4A1 BIN2 FAM204A FAM228B IRS2 KCNA3 TOB1 COMMD9 HAUS3 CGRRF1 EPHA4 BRWD1 TTC32 TTC28	down	**
GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_DN	0.0096030	0.0405074	0.3807304	0.3722846	1.530026	87	MNX1 ATP6V0A4 GPR156 SLC5A5 GRIA4 EPHB3 HOXB-AS3 FAM81A SPINK13 TMC1 LPAL2 ALDH1L1 C5orf46 CHRDL2 GLB1L2 FHOD3 KCNJ11 PKMYT1 PON1 PANX2 SLC24A2 TCTE1	up	*
GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN	0.0023119	0.0130822	0.4317077	0.3475291	1.529910	146	TRIP13 BIK HJURP SPINK13 PRSS2 UCHL1 TM4SF18 IFI27L1 ILDR1 LAMP5 PTTG1 AKR1C1 SFXN1 TYMS MYBL2 IGFBPL1 COPB2 LILRB4 ZWINT SCG5 NME1 LGMN VASH2 HYDIN RRM2 CDCA5 SLC37A3 KDELR2 MGLL SEC61G PSAT1 PSMA5 TK1 SIL1 CEP128 CHPF KDELR3 LRRC59 PPCDC CREB3L2 PDIA4 ZNF195 FARSB SEC13 RPN1 CENPE IGLV3-19	up	*
GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN	0.0013809	0.0087715	0.4550599	0.3380577	1.529263	186	PAGR1 MPP6 NDC80 BRCA1 GMPS GINS4 CCT2 MELK CISD1 KNTC1 PUS7 LARS2 COASY RBM28 AIMP2 EMG1 KDELR2 DNAJC9 CAD PHB IDH2 DDX56 HDGF POLE2 CCT3 PSMB5 MCAT MRPS2 NEIL3 PSMC4 RTP4 KPNB1 RANGAP1 DNAJC17 DPP3 GSS LONP1 CASP7 ANAPC1 FHL2 CCT7 RAD50 RNF187 ORMDL2 PPP1R8 HMGA1 FAM136A HEATR1 DUS4L RCC1 GLO1 DOHH BLVRB NDUFA8 CDK5 CENPE PPIA NCAPD3 RAD1 DDB2 NAT10 DNM1L ILVBL PPP1R14B ACSL5 PRKAG1 ERLIN1 CYB5B CD38 RNF14 AVEN MUS81 CLPP RWDD2B TMPO BATF TEFM	up	**
GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN	0.0008743	0.0060251	0.4772708	-0.2914301	-1.529130	161	CXCL3 IL17RB SWAP70 TSPAN4 DENND5A PPARG MYADM IL1RL1 SLC44A2 ENTPD1 PAQR3 PAG1 TRAF6 GPM6A EXOSC9 PTGIR AHNAK KLF11 SOCS2 NFKB1 CDKN1A DUSP11 SHE MATK GNAQ N4BP1 AFF1 RPL17 AREG IL6 APPL1 ARL5B SH3BP5 KCTD12 PTGER4 SKIL COBLL1 PIM1 LGALS3 CCR1 KAT2B SERINC3 RXRA BMP2K TPT1 FBXO30 ITGAE	down	**
GSE10325_MYELOID_VS_LUPUS_MYELOID_DN	0.0004242	0.0033284	0.4984931	-0.2865023	-1.527852	182	KMO AQP9 QKI FLVCR2 ZCCHC2 SLC39A8 MARCO IL1RN LAMP1 EPB41L3 IGSF6 ADAM17 GM2A ZNF410 HLX LAIR1 SLC25A37 TNS1 TFEC TXN ATP10A ADO KLF9 VRK2 CTSD ATG7 GMPR CDS2 CTBS PLEK PEF1 PAFAH1B1 HESX1 PHACTR2 RAB8B OASL GABPA ACSL1 SIGLEC1 CALM1 PTP4A1 EMC7 MILR1 CRYZL1 DPM1 PIM1 ADPGK KYNU	down	**
GSE42724_NAIVE_VS_B1_BCELL_DN	0.0022251	0.0126709	0.4317077	0.3403378	1.527380	172	GGCT GPR35 MRPS35 DCTN2 NEURL2 SPDYE1 EEF1E1 POLD2 PRKDC FBL DCTPP1 TIMM50 LRRC45 PES1 TMED3 MRPL36 MEA1 EXOSC2 MRPS2 ZNF584 NRGN OVOL3 ATP6V0E2 LMNB2 MRPS34 ARL6IP4 DPH2 S100A9 MRPL4 ANAPC1 SND1 MRPL24 PRMT1 TMEM147 RABEPK EIF3K ALG8 JAKMIP3 TMEM117 DOCK3 GTF3C2 SNRPD2 CCDC167 HLCS COX5B SLC25A29 PFKM RHOT2 AURKAIP1 TIMM44 APEX1 MRPS27 PTOV1 NUP210 MRPL48 TMEM161A TPM1 EIF2D PPARGC1B MRPL12	up	*
GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP	0.0006770	0.0049009	0.4772708	-0.2874547	-1.526897	177	SIDT2 DENND5A SNX10 CAT LY86 S1PR1 MANBA CD1C TGFBR2 GGA2 KIAA0355 ITSN2 ATP6V1B2 SRSF5 GCA RAP1GDS1 MAPRE2 ARHGDIB SNN STK24 RPL17 USP25 PKIG FRY CDC40 KIF13A RBM34 ESD HMBOX1 IRF8 PSTPIP2 MORC3 REL EGLN2 SLC25A24 PKIA CD74 GSAP DCK CRYZL1 TSC22D1 DYNC1LI1 SLC24A1 KYNU ZNF267 PPID RBL2 TNFAIP8 ESYT1 LYST FAM13B WDFY3 ENDOD1 ING1 BBS7 CD79B PAX5 SGPP1 ZNF22 PNRC2 RNF111 RPA2	down	**
GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN	0.0015567	0.0095783	0.4550599	-0.2912080	-1.524992	157	CXCL3 EREG IL1A CD55 IL1B LTA4H PID1 COQ2 FYN RADIL BCL2A1 ATP2B1 PTPRM CARD16 FAM124A MPHOSPH6 BNIPL TCF7L2 AGO3 CASP1 PLAUR STK17B STX3 CXCL2 ALOX5AP PINK1 IL24 KREMEN1 PROCR FMNL2 DDX60L NSMAF SH3BP5 CELF1 CCDC50 PNPLA8 ZBED5 SNX9 TGIF1 TSC22D1 IRS2 CCL20 BNIP3L CDC42EP3 ING2 BCAT1 RET IL16 RABGEF1 LINC00922 CRBN CLEC4E SLC19A2	down	**
GSE3982_MAST_CELL_VS_BASOPHIL_DN	0.0008935	0.0061052	0.4772708	-0.2922692	-1.524985	168	EPAS1 ABHD5 ARHGEF15 MYD88 YPEL5 GIMAP6 PILRA DNAJC3 SPTBN1 ZFYVE16 TCAP PDE4D MAP1LC3B DENND3 PTPRC DUSP11 DUSP1 ALOX5AP CCDC59 RPF1 N4BP2L1 PPP2R5A LMBRD1 HSDL2 ARHGDIB ZCWPW1 WASF2 BCAR3 UTRN NECAP1 CD48 RAB31 JAK1 RASSF2 DYM UBB PELI1 VAMP4 TMEM230 HBP1 EXOC1 MACF1 ETS2 ARAP2 SELPLG CCDC69 ACTB MARC1 RNF38 FOXJ2 DAZAP2 CCND3 PMAIP1 CSF2 HTRA2 CDC14A TMEM50A ZNF106 CX3CR1 OSGIN2 RB1CC1	down	**
GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP	0.0008449	0.0058722	0.4772708	-0.2911836	-1.524593	160	FCN1 IL1B MIR22HG SIK1 LDB2 YPEL5 TRIB1 IER2 ANXA1 DNAJC3 ASAH1 CLEC7A RNF125 TCF7L2 FBXL5 ITPRIP KLF4 COQ10B KLF11 ID2 SNORA28 DUSP1 RNF139 IL7R C16orf54 VCPKMT HCK SLC25A33 TMEM9B SGK1 JUN SNX29 RAPGEF1 ATXN1L SKIL CD83 GRASP KLF2 PTP4A1 ZNF669 BIN2 NAP1L5 GSAP ABHD13 ZNF844 IRS2 GABARAPL1 KANSL2 RGS2	down	**
GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_UP	0.0015670	0.0095783	0.4550599	0.3390703	1.523793	176	GGCT AGFG2 ASIC1 AP1S1 TTC26 CDCA8 CENPA TPX2 E2F3 CCNB2 HMMR NLE1 MCM7 RAD54L KIF11 DCTPP1 SYMPK FAHD2A BIRC5 ATIC MRPL17 ARNT2 PIAS3 SNRNP25 MZT2B UQCRFS1 COA3 PUS1 MLF2 PINLYP PKP4 ZNF768 CCDC51 RNF187 PTER TIMM13 STOML2 IARS2 FAM136A BCL2L1 MRPL24 BLCAP PRMT1 NFE2 ESRRA STK39 PYCR1 PPFIA3 CHMP1A RSAD1 EYA4 VDAC3 GGCX SRPRB PPP2R5D TK2 PCTP CYB5B DNAL4 CAMK2N1 ACSBG1 EIF2B1 PRPF19 DSN1 CAMK2G NHP2 MTMR4 PRCC RFX7	up	**
GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN	0.0008413	0.0058554	0.4772708	-0.2875919	-1.523523	175	IL1B LRRFIP1 BAIAP2 RBM14 BCL2A1 HPS5 ATP2B1 LTBP4 HBEGF ADAM17 PAQR3 GLS NFE2L2 NDEL1 SPRY2 ZFYVE16 SRGN MAP2K3 ADO NFKB1 ATF3 CDS2 VIM HOPX MATK EMP3 NSMAF PGD PNO1 CYCS RHOG TMEM251 IPO7 SP3 HOMER1 NOL7 CDK17 HIVEP2 PEA15 BAZ2B ATP6V1A NAB1 PDCD1 GNG5 CD81 MBNL1 GEM ANKLE2 WDR1 UBE2D1 IPO5 TRAF1 COPS8 ZNF165 PSMD9 NUP160 FEZ2 SNRPG BCL10 TSC22D2 GABPB1 KLHL9 ORC4 CFLAR GTF2H1 DUSP2 IVNS1ABP SENP6 ADAM19 GNL2 SUCLA2 EIF4A3 PSMD14 EZR AGO2 FASLG PTPN22 SACS SEC62 PRNP	down	**
GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_UP	0.0015670	0.0095783	0.4550599	0.3389924	1.523444	176	SPATA24 C1GALT1 NUP107 SLFN13 DNAJC12 MND1 KIF18B THOC3 NDC80 PIF1 SORD BAIAP2L1 NUF2 CDCA8 ESPL1 TFDP2 CCNF SMARCC1 KIF23 KCNN4 MKI67 WDR78 KLHDC4 KIF11 GPSM2 PFN2 CKAP2L XRCC1 SPC24 IDH2 RASSF6 CMAS CTDSP2 CDK1 NCAPG ANAPC7 PLCG1 RTCB NADK2 DHX40 MBD4 TRIM37 LRWD1 SLX4 CDC7 SASS6 BRD8 MAN2A1	up	**
GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP	0.0005776	0.0042577	0.4772708	-0.2867203	-1.523250	179	SIDT2 CD52 SWAP70 SLC47A1 MIR22HG TRPV2 COQ2 BACH1 FOSL1 PCOLCE2 FUCA1 EOGT TEX2 EIF4A1 HSPB1 PICALM LAIR1 SIRPA CES1 CYBRD1 PPT1 ACSL3 CPVL PXDC1 UHRF1BP1L SLC7A8 CEBPA STX3 ERP44 ITGAX TM6SF1 INHBA MATK HCAR3 CTSS TREM1 CD83 CXCL5 NDUFV2 ACSL1 AZI2 NOP10 PSMD12 FXYD6 TSC22D1 GALC CPT2 APLP2 CLASP2 CLEC2B PLA2G15 AMD1 CEP170 RTN1	down	**
GSE360_L_DONOVANI_VS_T_GONDII_DC_DN	0.0034563	0.0178760	0.4317077	0.3440994	1.522859	154	KIF1A ALDH3B2 FOXM1 HABP2 RUVBL1 AP3B2 BUB1B PROM1 IGF2BP3 IQCE EIF2B5 NDUFS6 SIX1 CCL8 ACOT8 ALDOC NME1 CYP24A1 AURKA POLA2 IGLV1-44 WIPI2 PDZK1IP1 MAD2L1 FBL XRCC1 CDK1 IGSF3 CCNE1 MTOR MLF2 LMTK2 MARCKSL1 RPA1 MCM6 PRMT1 MCM5 CHRNA5 MSH2 MMP16 NME4 ANK2 GNE TBL3 NELFA VNN1 SARDH BEAN1 IFI44 GSTP1 CADPS NHP2 MTMR4 MTR DYNLT1 CALM3 IGF1R STMN1 IGLV3-25 ACTN4 TNFSF4	up	*
GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_UP	0.0067172	0.0308155	0.4070179	0.3676792	1.522237	92	MNX1 KLC3 SPATA24 PPP1R1B KRT5 PCLO PYY2 DIO2 GRIN2A SAMD15 SLITRK5 SLC34A3 FHOD3 WDR72 C11orf16 EGFR LINC00265 PKMYT1 GRHL2 C9orf163 PANX2 SEC16B FNDC4 EDARADD DNAJB13 IQUB TNS4 CDCP1 VWA3A ELFN2 ZNF257	up	*
GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP	0.0026947	0.0146526	0.4317077	0.3443220	1.522072	153	MUC4 PBK BRCA1 DIO2 CCNF GOLPH3L SOX30 TP53BP1 KNTC1 EXOC4 TMEM184A KIF2C POC1A CDCA5 HOXC6 WNT1 CHAD FAM162A NUDT17 B3GNT3 TIMM50 SPATA17 GEMIN7 PML NAA40 SPACA4 VANGL2 OARD1 LRRC56 DIAPH3 PYROXD2 MYO19 C19orf18 CCNE1 SCLY NMRAL1 TJAP1 SGSM3 ANAPC1 TRAF3IP1 CLTB SULT1B1 SASS6 KRT8 KDM4B GID8 USP21 LANCL2 C1orf109 VWA3A PRR11 STAB1 CARHSP1 LLGL1 MXD3 ESPN SIAE ARHGEF10L C4orf46 LUC7L3 CRYGS SH3RF2 PCNT CYP8B1 XAF1 DHX32 AP1B1 GCNT1 GOLT1A CMPK2	up	*
GSE17721_0.5H_VS_4H_POLYIC_BMDC_UP	0.0031237	0.0164706	0.4317077	0.3401174	1.521937	166	PTPRZ1 TP63 FOXM1 SPICE1 BDH1 EPN3 ELOVL6 CREB3L4 CDK4 INTS1 TOP3B CEP250 SAE1 MCM7 MAD1L1 GPR146 MCM3 CCDC58 FAM162A KDELR2 GET4 CC2D1A FBL MSI1 TIMM50 SAMD10 PPP1R37 MEA1 TAF6 LZTR1 POLR2H DPH2 PCSK4 SLC26A1 GTF3C1 CPSF4 ORMDL2 BCL2L1 MADCAM1 CYP4F12 HAUS4 ERGIC3 CORO2A CEP85 LHX4 GTF3C2 TRIP4 ENPP5 EARS2 GPX7 CDKAL1 NPR2 MRPL48 NCAPH BMF SPHK2 PNPO LCMT1 NHP2 SHMT1 ZNF790 SPRYD4 SRSF9 HAAO TPH1 PPP4C C15orf40	up	*
GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP	0.0018723	0.0110164	0.4550599	-0.3017358	-1.521720	132	SOSTDC1 PLEKHF2 CGNL1 STX11 NR3C1 NFATC3 PEAR1 FGR ANXA1 ATP2B1 DNAJC3 LTBP4 RNF125 STOM SLAIN2 GRN GPA33 ARNTL KIF26A CDKN1A UXS1 PIK3C2A PLCD1 PTH1R NCOA1 MYO1C FRY NDNF C1QA NDST1 XYLT1 IRF5 CNTNAP1 KCNA3 APLP2 SPOCK2 PHLPP2 CCR6 GPX3 TIAM1 ADORA2A B3GNT2 IQGAP1 LPAR6 PMAIP1 EGR1 C1QB	down	*
GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_UP	0.0047523	0.0233164	0.4070179	0.3535779	1.521252	124	CDHR2 BHMT AP3B2 CHEK2 DNAJC22 DEPDC1B C6orf141 ASIC1 FA2H ANKRD24 LAMP5 CCNB2 CYP27B1 ARHGAP33 CDC25A EME1 AGT ADM2 AMACR MYRFL C22orf46 FDXR FUT2 BMP5 C2orf50 SPATA6L DMGDH CDH3 EFCAB1 LINC00649 CPXM1 EVC2 FER1L5 COL9A2	up	*
GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN	0.0004732	0.0036301	0.4984931	-0.2860526	-1.520858	180	RAB11FIP1 ZC3H12C PTPRE FIG4 LMO2 TXNL1 GFOD1 HEATR5B PLEKHA1 P2RY13 ZEB2 ATP2B1 RNF144B RNF125 PTX3 GPBP1L1 ASH2L MOB3C PPM1K FBXL3 CXCL2 PLEK MIR17HG AFF1 NRROS SERTAD2 ARHGAP17 GPBP1 PRKRA SLC25A25 PKNOX1 BCAR3 C2CD2 MTMR14 CELF1 FOXN2 GPR183 PTGER2 SUCNR1 TCP1 NDUFV2 GRSF1 ATG3 PPTC7 GSAP RSBN1L MIA3 CD86 KYNU KTI12 ARAP2 SETDB2 UBE2D1 MEGF9 RAB2B NRP2 EHD4 STARD13 DUSP6 CCDC112 ATF2 LIN52 MZT1 ANKS1A	down	**
GSE7852_LN_VS_THYMUS_TREG_UP	0.0008804	0.0060585	0.4772708	-0.2870489	-1.520647	175	CXCL3 ARHGAP31 GPR15 HVCN1 SPN LPXN RUNDC3B PEAR1 ABCB1 PDE2A ARSB MS4A1 SRGN CYP4V2 ARRB1 SYNPO AGO3 CASP1 ATP6V1D ABCC4 TMBIM1 NR1D2 HOPX SHE ELMSAN1 BRF2 GNAQ UBASH3B MYH11 BCLAF1 HLA-DQA1 TANC1 HGSNAT FOXN3 RPS6KA2 KIF13A WSCD2 ST6GALNAC4 PTGER4 PRKCE PTGER2 SH2D4B CST7 NDST1 SNX9	down	**
GSE7852_TREG_VS_TCONV_UP	0.0004732	0.0036301	0.4984931	-0.2860031	-1.520595	180	SWAP70 DENND5A CLDND1 ARRDC4 LONRF1 BMPR2 RXFP1 C3orf70 LYRM4 MAP3K8 PAQR3 TMEM123 TFRC PIP5K1B YBX3 ST3GAL2 SOCS2 SOCS5 ITIH5 NFKB1 CYP20A1 SHE PLEKHB2 ELK3 B9D2 MATN2 MATK GNAQ N4BP1 UBASH3B NCKAP5 SACM1L SNX3 PRKRA CD80 PHTF2 KIF13A ELP5 GSTO1 CD83 IRF8 TNFRSF9 OGFRL1 ZBED5 YPEL2 PDCD1 CD81 NRN1 POLK CCR6 CALHM2 TIAM1 ITGAE	down	**
GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN	0.0009881	0.0066403	0.4550599	-0.2883622	-1.520009	172	LPIN2 FYN DDX6 CORO1C GTF2E2 IDI1 APIP NUDT9 CD9 IL1RN ANXA5 LITAF SLC7A11 LCP1 PPP2R2A NDEL1 LAMTOR3 SRGN TUBB6 STAT5A SORBS1 CDIP1 ARNTL ATP6V1D SOCS5 FBXL3 CDKN1A ID2 M6PR EXOSC8 IL7R EBF2 RAB8B DHH STAT4 MAP4K4 PTGER4 IFRD1 CD74 EHD1 AP1G1 KCTD10 C16orf72 GABARAPL1 STX12 CRY1 GNA13 CSNK2A2 FKBP1A SLC31A1 ARIH1 ACTB TDRP	down	**
GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	0.0004074	0.0032170	0.4984931	-0.2855780	-1.519814	184	FBP1 CYP27A1 LY86 C8orf58 MSRA ALAS1 ELMO1 NCF2 TGFBR2 FAM49A PDE2A EDEM1 SLC44A2 ARSB GM2A CLEC7A LITAF BFAR TFEC TUBB6 CD37 SORBS3 PPT1 SPNS3 FUT7 TMBIM1 ITIH5 COTL1 PTPRC VIM TLR4 ELK3 WFS1 ZNF706 ARHGDIB NRROS RPS6KA2 SOCS3 APPL1 RGS18 MITF STAT4 SH3BP5 RAC2 BTD TREM1 PTGER2 CD34 CDK14 NKG7 DGKG SMPDL3B TESK2 TEC	down	**
GSE7852_TREG_VS_TCONV_FAT_UP	0.0008611	0.0059676	0.4772708	-0.2863295	-1.518316	181	ARHGAP31 SWAP70 PPARG LRRC8C TMEM170B MTMR10 STX11 ANXA1 EIF4A1 GM2A ZNF503 CYP4V2 KDSR ARRB1 SORBS1 NPNT ZCCHC24 TMBIM1 CDKN1A ATF3 HOPX M6PR DUSP1 GNAQ SNX3 ELF1 AREG ARL5B MITF IFNGR1 ENPP4 COBLL1 SERPINB6 ATP13A3 TNFRSF9 APH1B SNX9 YPEL2 IRF5 TGIF1 GALC PDCD1 DBNDD2 FAM98B GEM SESN1 IL18 ITPRIPL2 ARL14EP SAMSN1 EHD4 PIEZO1 RABGEF1 DMXL2 HERPUD1 JDP2	down	**
GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN	0.0015708	0.0095783	0.4550599	0.3377475	1.518009	178	DDX11 MDM1 RUVBL1 BUB1B FLAD1 PLK1 ALDH18A1 KNOP1 PRC1 PIP4K2C RANBP1 NDUFB8 ZNF443 TRMT61B DSCC1 SNAPC4 PPP5C HPS4 HARS2 ZNF45 ING4 BIRC5 ATIC GMNN POLR3K LARP1 FEN1 SSX2IP MRPS12 PLCG1 GOLGA5 RNASEH2A FAM86C1 MPI SNRNP25 ZGPAT UQCRFS1 TUBG1 VPS41 FMO6P GINS2 MRPL4 KDM3B PTER CENPM YLPM1 RPA1 BAD BLCAP RABEPK LSM4 TXNL4A WDYHV1 UNC119B	up	**
GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN	0.0005059	0.0038091	0.4772708	-0.2854667	-1.517743	180	MIR22HG CLDND1 STX11 RFTN1 TMX4 ANXA1 UBL3 TTYH2 STOM SRGN BTG3 TXN CD58 EVI2B AGO4 LIMS1 COTL1 HOPX EPS15 ALOX5AP LACC1 RNF149 PHTF2 KLRB1 PHACTR2 AQP3 SH3BP5 GLIPR1 CDK2AP2 OGFRL1 TBX21 TIGIT CD74 AKIRIN2 PEA15 DUSP5 ATXN1 LGALS3 CCR6 TRAC SLC35D2 CALHM2 CDC42EP3 ARHGAP18 S100A4 CTSC KIF1B RORA NABP1 IQGAP1 SPOPL MIS18BP1 PIEZO1 SH3BGRL3 ITGB1 MTSS1 ATP2B4 CD226 MYO1F CBLL1 ADAM19 PLXNC1 MFHAS1 CPPED1 GZMK IL10RA CAPG ZC2HC1A TMEM64 GZMA IQGAP2	down	**
GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN	0.0008351	0.0058292	0.4772708	-0.2898361	-1.517371	162	GIMAP8 CD44 TMOD3 AKAP7 IDI1 HMGCR TNFRSF8 STARD4 LMNA NAAA KLF10 CAV2 GPBAR1 TUBB6 RHOB FBXL5 ARRB1 DUSP3 SCP2 ZCCHC24 KLF11 ARNTL IRAK2 CYP20A1 ID2 MIR24-2 CCND2 PLEKHB2 PLEK ZMPSTE24 ARL4A C16orf54 SPIN1 SGK1 C2CD2 ARL5B PLK3 DNAJA1 GRB2 CAP1 RALB PTP4A1 TTBK2 ZFAND6 EHD1 GALC PDCD1 ATXN1 DOK2 POLK CYB5R4 ARHGAP18 ARL14EP OSER1	down	**
GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_UP	0.0073559	0.0329377	0.4070179	0.3577108	1.517109	115	PDE11A PTPRT FGA FUT6 KRT5 ADRA2A STAB2 PPP1R14D ECE2 ALDH1L1 SLC4A3 B4GALNT1 SYT12 NPFFR1 SLC6A20 STRA6 GPR37 F2RL1 TRIM29 HAVCR1 RAD54L SALL2 NEK11 THPO NRSN2 ASF1B TRIM2 CDH3	up	*
GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN	0.0013685	0.0087298	0.4550599	-0.2924453	-1.516869	151	RAB11FIP1 IL1A ZC3H12C HCAR2 CCRL2 CDC42EP2 PRPF38A STX11 IGSF6 BTG2 MAP3K8 FOXP1 HIPK3 PLXNA4 BIRC2 ZFAND5 FBXL3 NFKB1 GPR85 ATF3 C9orf72 CCL4 PLEK N4BP1 SPRYD7 RASGEF1B DDHD1 SOCS3 MTMR14 NXPE3 CD83 MALT1 REL ACSL1 PELI1 HIVEP2 NAB1 CNOT7 PIM1 SOD2 TAGAP BRI3 GPR18 RNF2 ICAM1	down	**
GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_1H_UP	0.0104309	0.0427772	0.3807304	0.3641330	1.516844	96	TF ASB4 WFDC2 ARMC4 DYRK1B C9orf116 SLC34A3 ANO7 TIMD4 AGT SMYD5 TRPV4 WWC1 PARD3 BTBD2 KIF5A PLA2G2A MAP3K10 KCNJ2-AS1 CRLF1 CYP2C8 ADAM28 SALL4 CHTF18 HID1 HNF1B WDR34 SMIM6 LINC00471 CCDC181 PTPRF LIF TMEM38A SNAP25 INO80B ARMC2 DNAAF1 CASC15 NOXA1 CYP3A7 CDH4 WNT8B KCND3 STAG3L1 LINC00654 STPG1 TAS2R5 EFNB3 ZNF546 PIEZO2	up	*
GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP	0.0011156	0.0073750	0.4550599	-0.2888730	-1.516628	167	SEMA3G SIK1 HSD17B11 SAMHD1 AKAP7 ELF2 YPEL5 MSRA RPL23AP53 FRAT1 ATF7IP2 TMX4 TXNIP ANXA1 DPEP2 LAIR1 SPTBN1 PDE4D MOAP1 TLE4 GPA33 ITM2B MGAT4A ARL4A PLCD1 MAPRE2 TBC1D5 AQP3 HECA CD48 JUN AK1 BAG5 NUDT15 UVRAG TSPYL1 FOS KLF2 PTP4A1 MMP15 IRS2 FCGRT TOB1 KANSL2 BNIP3L RLF IQSEC1 ZBTB25 NLRP3 ACACB S100A4 OSER1 RBM48 DAZAP2 NR3C2 PPP1CB ARHGEF18 ITGB1 FAM8A1 ZFP36 DNAJB1 PIAS2 LDB3	down	**
GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN	0.0023289	0.0131170	0.4317077	0.3407853	1.516512	161	MDM1 CHRNG PLK1 UHRF1 NLE1 IDO1 SLC29A2 YKT6 POC1A EIF2AK1 PPP1R35 SARS2 AKT2 NAA40 THOP1 CKS1B KCNE3 TNFRSF25 DCBLD1 NCAPG NF1 CHCHD2 G6PC3 TELO2 NINL ARF5 ATG9B MRPL4 SMTNL1 NTN3 ZBTB45 PPHLN1 LIPG C16orf58 TBCA CDC42BPG TFAP4 PYGO2 CUBN ESRRA C1orf122 RPS26 PRR11 R3HDM4 TOMM40L TAB1 TMED9 TMEM101 ETHE1 CIAPIN1 EIF4G1 C1orf159 ZMAT2 ALG1 SRPRB FBXO34 SIGMAR1	up	*
GSE3982_DC_VS_TH2_DN	0.0014217	0.0089377	0.4550599	0.3382739	1.516252	170	TRIP13 KIF20A FANCI TROAP CENPF POLQ TFF3 PTTG1 SFXN1 CCNB2 BCL2L14 TYMS ORC1 GINS4 AGK HMMR DPY19L2P2 KIF15 THBS4 TPR KIF2C MPHOSPH9 PDCD5 PASK GPSM2 DNAJC9 PERP MB ASF1B BIRC5 TESC PSMC4 LAPTM4B DLGAP5 SPTBN2 GALNT3 COX10 MARCKSL1 AAMP SUPT16H TWIST1 KIF21B GINS3 DOLPP1 ATAD2 CCNA2 ARHGAP5 ARHGAP11A PAXIP1 ZNF142 EIF4G1 E4F1 SEPHS1 SYNE2	up	**
GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN	0.0007150	0.0051226	0.4772708	-0.2856076	-1.515719	176	KMO AKAP5 CYP27A1 LMO2 TMOD3 ST3GAL6 NEDD9 HEG1 CASP9 CD36 STARD9 IFI30 CNTD1 CYB561A3 FOXP1 MS4A1 SLAIN2 PPM1K REST FAM49B ZBTB43 RNF139 PLEK HLA-DQA1 MTPN RBM39 HCST HECA SF3B1 KCTD12 DHX15 FYTTD1 RBM22 MOB1A CDK17 MBP ICAM2 BAZ2B PDE4B EMC4 ATAD2B BMP2K BLOC1S2 IQSEC1 CUL3 CEPT1 CYTH1 PAIP2 LDLR NABP1 LPAR6 GIMAP4	down	**
GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP	0.0015332	0.0095182	0.4550599	-0.2879271	-1.515392	169	RBP4 CXCL16 PPARG LRRC8C P2RY1 EMP2 GPR65 BMP2 LY86 AQP9 GAS6 CBL HBEGF NLK GRN SRGN RHOB AHNAK MED11 ST3GAL2 NES PRKD3 ITGAX CDS2 EPS15 SPRYD7 DEGS1 TANC1 CNRIP1 VWF HEXB RAB6A SACM1L NINJ1 TMOD1 ESD C20orf194 ETS1 APBB2	down	**
GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN	0.0006887	0.0049550	0.4772708	-0.2849064	-1.513613	179	PECAM1 PPARG LTA4H DCSTAMP P2RY1 STXBP6 CCDC88A CLYBL ZCCHC2 ESAM PAFAH1B2 TGFBR3 TXNIP ANXA1 ARHGAP10 CLCF1 CHMP1B ZBTB21 ZNF697 TFRC ATP6V1H ZADH2 SOCS5 CLIC4 RBMS1 DUSP11 MATK PRICKLE2 ZNF706 PTGIS LMBRD1 ARL6IP5 PPIL4 S1PR4 SLC25A25 ESD PLEKHA3 NXF1 PPA2 CNNM2 AK1 GYPC	down	**
GSE43863_NAIVE_VS_TH1_EFF_CD4_TCELL_D6_LCMV_DN	0.0075409	0.0335826	0.4070179	0.3575579	1.512985	111	CNGA1 BIK ASB4 C1QTNF6 C2CD4A GUCY2C MKS1 NAALADL2 SAMD15 RAB36 SLC7A9 IDO1 CHAD INPP4B ATP6V0E2-AS1 ZNF419 DPH7 RTP4 WDR24 PPP1R36 GBP5 POLR2H ZNF687 TSNAXIP1 PSME2 PTGER1 KRBA2 ZNF502 ASB6 PRODH NTN5 ESRRB SPAG4 NCDN FLRT1 RNF213 EPSTI1 FGFBP1 KIF24 CYP11A1	up	*
GSE35543_IN_VIVO_NTREG_VS_IN_VITRO_ITREG_UP	0.0040133	0.0203252	0.4070179	0.3502902	1.512830	127	PKHD1 PRLR FAM83F CCL19 KCNMB2 GRIA4 MDM1 LAD1 NAALADL2 DPYS FAM169A STAG3 CBLC METTL7B SOX11 TBC1D8 FBXL8 OSBPL7 C2orf50 CD300A SERTAD4 PLA2G2A ESRP1 CCT3 VPS28 WDR86 CCL21 KY MROH9 HECTD1 SEMA4G PLEKHB1 C15orf62 KIAA0100 SMIM6 RSPH4A ALMS1 MMP16 SCRG1	up	*
GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_12H_UP	0.0013909	0.0087833	0.4550599	0.3368276	1.512781	175	TRIP13 SCIN RUVBL1 MCM10 BUB1B C17orf75 TRIM17 PRIM2 ESPL1 RBBP8 ORC1 CCT6A VILL SPDL1 WDR62 EME1 POLD2 KIF11 PASK CHAF1B SPINT1 MRPS11 ETFA ZCRB1 NUSAP1 ANAPC5 SPATA6L CENPJ GNB1L C1orf112 NPM3 DNA2 WDR31 SPAG5 NF1 CHCHD3 C19orf44 FOXRED1 MORN2 ZNF239 SYT1 PRMT7 LRRC20 NRF1 NUP85 ATAD5 CENPK PSMB3 BRD8 RPA1 KPTN LSM4 CEP152 MSH2 MCU WDR76 AURKAIP1 NTN1 CENPE SWI5 NMT1 EPHB4 SMARCB1 C4orf46 NUP93 PARP2 RCN2 UTP18 ZC3HC1 HINT1 FOXRED2	up	**
GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN	0.0010109	0.0067836	0.4550599	-0.2899221	-1.512738	168	ACP5 PLEKHA1 STX11 NR3C1 MANBA EPB41L3 KIAA0355 SH2B3 NDUFAF7 IFI30 NLK ADARB1 PTGIR DRAM1 MAP1LC3B PDE3B SIK2 CD302 CLK4 DUSP1 PLEK N4BP2L1 GNRH1 HCK FOXN3 MYLIP RBPJ DCP1A PDE6B BTD CCR7 DAPK2 TNFRSF9 ZBED5 POGLUT1 PNPLA2 SPOP TGIF1 TSPAN14 HBP1 CPT2 N4BP2L2 SYT11 BNIP3L TIAM1 PTCH1 MEGF9 NFU1 AFTPH CD70 CSF2RB NR4A2 CX3CR1 AOAH PDCD2 TREM2 GPR137B STX16 IL5 ATP8A1 ZFYVE21	down	**
GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN	0.0019047	0.0111667	0.4550599	-0.2885991	-1.512545	159	ARRDC4 PDE1B AKAP7 EML1 PAFAH1B2 AGPAT4 MOB1B STARD4 LMNA CAV2 GATA3 TFRC TUBB6 FBXL5 KDSR DUSP3 LRRC57 PXDC1 ITIH5 ATF3 IRAK2 MIR24-2 SHE GNAQ UBASH3B STK24 SPIN1 C2CD2 GLUD1 RPS6KA1 TNFRSF9 YWHAZ APH1B GFPT2 YPEL2 CRYZL1 TEC TSC22D1 LGALS3 SETDB2 RTN4 RAB5A ARL14EP CCR9 KIT PSMD6 ATP6V0A1 TMEM30A TMEM43 HMGCS1 ZFP36 FAR1 PTGS1 CD69 SLC25A19 ARHGEF12 ATP8A1 KATNAL1 PLCB4 SRXN1 ZFP1 EIF4E3 PNP PLCL1 MTDH SCAMP1 DCTD TMEM64 STK10 STX2 PADI2 SLC37A2	down	*
GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_DN	0.0007373	0.0052515	0.4772708	-0.2868106	-1.512255	173	ARHGAP31 CD52 ARRDC4 LPL LY86 SAMHD1 ALAS1 PILRA DNASE1L3 NAAA CLEC7A IFI30 SERPINB9 TFEC TXN CASP1 DRAM1 VASP STX3 RMDN3 PLBD1 ABCC4 ITGAX HOPX AXL GCA INSL6 HSDL2 USP25 INPP5B HK3 ELP5 IRF8 CST7 CD164 CD74 SMPDL3B ADPRM CD1D FPR2 GNB4 SOD2 STK40 PLAA PCCA IL18RAP ALDH1B1 SEMA4A EDN1 DOCK10 KLRK1 THEMIS2	down	**
GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN	0.0015950	0.0096896	0.4550599	0.3366671	1.511101	177	NUP107 GGCT RACGAP1 POLE ALDH18A1 CCNB2 CCNF ZWINT MYL6B RUVBL2 EXO1 KNTC1 BUB1 ERAL1 MCM3 THYN1 ORC6 PFKP PKMYT1 ETFA MNAT1 CKS1B CMAS GMNN MCAT MRPL17 FADD SNRPE RTCB FOCAD CHCHD2 GNPAT FAH GINS2 CCDC51 PSMD2 ENPP2 PSMB3 BCL2L1 PELO STAMBP MCM5 SNRPD1 LSM4 KLHL7 NUP62 NDUFV1 DCPS ATOX1 RAD51 CPOX EIF4G1 POP4 SEPHS1 PPIA COX17 ERLIN1 TBC1D10B FASTKD3 BATF GCNT1 MTHFD2 COX6A1 SMC4 CTPS1 PSMD8 ACOT7 P4HA2 HMBS MRPL35 MRPL13 EDC3 RFC3 CNOT6 GALK1 TARDBP GIGYF2 PSMC2 SNRPB SDC4 PARK7	up	**
GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_DN	0.0085228	0.0370504	0.3807304	0.3728601	1.510414	82	NPC1L1 FAM227A CPLX2 FER1L6 CBY3 MUC4 ILDR1 DPYS ARMC4 KREMEN2 METTL7B MARK1 CLMN FCRL6 SYN3 KSR2 ARTN LRRC56 CADM4 PINLYP GNAZ MAT1A IQUB KCNIP3 NAT8L GNAL ROS1 ADCY1 ABO CELSR3 APOBEC4 KCTD19	up	*
GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_DN	0.0018705	0.0110164	0.4550599	-0.2881439	-1.508946	157	STAC GLIPR2 TRPV2 EGR2 PCOLCE2 ANAPC15 GGA2 ABCG2 ANXA5 FOXP1 PTX3 C1orf162 ADRB2 TIPARP KLF11 STK17B GNAQ IL7R HGSNAT PRCP S1PR4 SCEL AQP3 SLC35E4 DNAJA1 PODXL KLHL18 SNX1 CAP1 PREX2 EGLN2 WDFY4 CTTNBP2 UBB HNRNPA2B1 DYNC1LI1 DOK2 ANKRD13A ADAMTS15 OPN3 CALHM2 RTN4 PIP4K2A CALCOCO2 EXD3 MEGF9 GPD1L	down	*
GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN	0.0046525	0.0228730	0.4070179	0.3453266	1.508821	137	EYA1 GABRB3 BHMT DNAJC22 GINS1 CDK4 ASIC1 FOXE1 FA2H ANKRD24 CALML6 KNOP1 CYP27B1 CDC25A CXCL10 DLG1 BOD1 CXCR5 AMACR CCDC58 FUT2 CXCL11 CCDC61 DMGDH GJB3 EFCAB1 CPXM1 EVC2 DVL3 COL9A2 COX7C C1orf131 CASP7 COLEC11 GEMIN5 DAP3	up	*
GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN	0.0011152	0.0073750	0.4550599	-0.2891303	-1.508607	168	CXCL3 ARHGAP31 TMOD3 BCL2A1 IL1RN CCNL1 FBXO7 NFIX MAP3K8 CNTD1 AKT3 TFEC SRGN IL10 BIRC2 RMDN3 CLIC4 LY96 MGAT4A CDKN1A UBE2E2 GPR85 ATF3 HTT SPRYD7 PIAS1 FLT1 PODN MITF LRCH1 CPEB4 KCTD12 JUNB SKIL CD83 PHOSPHO2 CGGBP1 DEDD ZNF407 ACSL1 AGFG1 HIVEP2 TCF4 ATAD2B GTF2B MIER1 XKR8 ALDH1B1 TIAM1 DOCK10 TNFSF9 FEZ2 MIER3 CSF2RB ZNF800 DYNC1I2 PLEKHA2 CHAC2 EXOC6 FCF1 SLU7 HIVEP1 NCOA7 SLC25A28 RANBP2 WHAMM IL10RA TANK	down	**
GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN	0.0019449	0.0113752	0.4550599	0.3356586	1.508461	176	KLC3 FOXM1 FAM81A CDC45 UBE2T KIF18B PIF1 DEPDC1B IQGAP3 E2F8 POLE STIL FIGNL1 TYMS WDR62 MELK HMMR EXO1 BUB1 TPBG POC1A ICA1 CPD PASK CDC25C CHEK1 ORC6 CKAP2L RAD51AP1 BRIP1 BLM SLC25A10 INCENP KNSTRN ADAP1 DNA2 SLC12A8 DAP RAPGEF5 SNRNP25 INTS7 HMGN3 CASP7 GINS2 KIF20B LCLAT1 FHL2 ERBB3 RPA1 HMCES IL12RB2 RCC1 STK39 NUP62 CYTH2 MMP16 AMDHD2 CARHSP1 RPP25L KIAA1522 ZBTB32 FAXC RORC NUP93 CYP11A1 CYB5B ESM1	up	*
GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_DN	0.0020917	0.0120172	0.4317077	-0.2886625	-1.508128	154	WEE1 TMEM52B GPR65 CCRL2 PLEKHA1 KCNN3 ACER3 PDCL SPCS3 TRA2B C10orf25 RANBP9 SLAIN2 BNIP2 DENND6A MVB12B ACTR3 ELK3 FAM76B CMTM6 TYROBP FOXN2 RC3H1 MORC3 GFPT2 BLOC1S6 AGFG1 YTHDF3 PSMD12 ZFAND6 PDS5B PDE12 TMEM230 ATXN1 CLASP2 DCTN4 VPS4B FBXO30 RBM18 G3BP2 CREBBP COPS8 ACADM SCAI FAM13B EIF4A2 ANO6 BMI1 EXPH5 HIPK1 ATF2 DYNC1I2 CSNK1G3	down	*
GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP	0.0009091	0.0061946	0.4772708	-0.2838104	-1.507540	177	CXCL3 RAMP3 IL1A RBMS2 ZC3H12C F2RL3 LYVE1 CDH5 SUSD2 IL1RN TRIB1 SBDS ITGA5 LITAF SERPINB9 NFE2L2 AKT3 RHOB SLC7A2 IL10 MOAP1 SOCS2 CDKN1A CXCL2 ATF3 CCL4 KPNA3 MAFF PROCR PDK4 IL6 INPP5B RAB8B ELP5 ATP11A RHOJ CCR7 IFRD1 CD83 EGLN2 SLC3A2 TREX1 ADPRM SAV1 SOD2 PDE4B ICAM1 SESN1 CTTNBP2NL ADAMTS4 NSUN4 SIN3A TIMP3 EDN1 NAA15 MT2A SPHK1 JDP2 SPSB1 CD70 SERPINE1	down	**
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN	0.0015561	0.0095783	0.4550599	0.3362131	1.507015	170	BDH1 FANCI PDCD2L GGCT SORD CDK4 TRIB3 SPINT2 GLB1L2 XPOT ZWINT RUVBL2 DNPH1 NLE1 TP53BP1 ZNF485 POLD2 RBM28 SLC37A3 FAM162A MAD2L1 FNTB BLM UCK2 GOT2 SMG9 MCAT DGAT2 MRPL17 GNPNAT1 FEN1 FADD OARD1 POLR2H SNRNP25 VBP1 SMG5 COA3 DNAJA3 OSBPL3 RAD51D SPTSSA DPH2 MLEC SPAG1 NIF3L1 LIMA1 ORMDL2 AAAS RRP9 POP7 MCM5 C1orf109 RCC1 VDAC1 ATOX1 ARHGAP11A TARBP2 PAICS RRS1 MRPS26 PPP1R14B BRIX1 FTSJ3 TMCO6	up	**
GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_UP	0.0023448	0.0131395	0.4317077	-0.3024536	-1.506884	122	SOWAHC TBX3 HSD17B6 EGR2 CCRL2 IER2 BTG2 NR4A1 SPRY2 MYOZ3 COQ10B ADAMTS9 CXCL2 ATF3 MAFF TGFB2 PROCR SLC25A33 SLC25A25 AREG IL6 KCTD12 PLK3 DUSP8 PPP1R15A REL HOMER1 FOS FOSB WNT11 PARD6A MIR23A DUSP5 IRS2 CEBPD TOB2 HES2 EDN1 TMCC3 NRG1 ELFN1 PMAIP1 EGR1 SERPINE1 NR4A2 ARL4D ZFP36 KCNJ1 DNAJB4 DPF3 AKAP12 NFIL3 NR4A3 PTGS2 IMPACT NFKBIZ	down	*
GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN	0.0015702	0.0095783	0.4550599	-0.2889613	-1.506841	152	CLEC1B FABP4 LPL ARL8B CD9 ATP2B1 RRAGC LMNA ENTPD1 CLEC7A TTYH2 STOM TFRC MTHFR ATP6V1B2 ATP10A AHNAK PTPRO CLIC4 SPAG9 NR1D2 ATF3 CDS2 ATP6V0D2 IL7R CALM2 CNOT6L VWF OASL CPEB4 HK3 MBNL2 GPR183 GAS2L3 PNPLA2 TREX1 TSC22D1 RELL1 APLP2 LGALS3 GABARAPL1 BRI3 ANKRD12	down	**
GSE14000_UNSTIM_VS_4H_LPS_DC_UP	0.0026678	0.0145712	0.4317077	0.3356972	1.506671	174	DEPTOR MSTO1 CCT6A SPDL1 TAMM41 GTPBP3 POC1A WIPI2 AIMP2 B4GALT7 OGFOD2 NAA40 DHRS13 DDX51 EXOSC2 MCAT FEN1 EFTUD2 SATB2 NADK2 SLC26A2 TACC3 ZNF544 NUDT16 CPSF4 POP7 UBXN6 PEX5 KDM4B THOC5 HAUS6 SNAP47 RAB3D GINS3 AATF TCHP ZSCAN16 SPSB3 SMARCA4 MLXIP POLR3B CLUAP1 RSAD1 GTF3C5 BCAS3 KDM5B NCAPD3 RRS1 NAT10 FTSJ3 C12orf10 ALKBH2 ZNF630 DCAF16 POLRMT PSTPIP1 MBTD1 SHQ1 SPHK2 BCL7A ATRIP ZNF77 SHB SLC7A6OS KCTD6 SWSAP1 HENMT1 EPS15L1 PRDM15 DEF6 ZBTB48 MPLKIP WDR12 SLC27A1 RFC3 CROT	up	*
GSE27786_BCELL_VS_NKCELL_DN	0.0008724	0.0060203	0.4772708	-0.2838994	-1.506654	176	GATA2 CYP27A1 MIR22HG CD44 RTN3 BMPR2 CTDSP1 SLC15A3 SLCO2A1 PDE2A NCEH1 DNAJC3 MCTP1 ADIPOR1 SPRY2 RAB14 ZMIZ1 ARRB1 PTGIR SGTB KLF9 MAP1LC3B ITPK1 RIT1 RECK FRMD4A TM6SF1 DSE NCOA1 EMP3 TMEM9B VAMP3 PRKRA NSMAF KIF13A INPP5B PDCD6IP CYB5R1 OSTM1 ATXN1L MBNL2 HSD17B12 RALB	down	**
GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_2H_UP	0.0080216	0.0354372	0.3807304	0.3610130	1.506314	102	ANKRD36C PTPRT HELLS PAX9 NEK2 PDCD2L NOVA1 LCN2 TMC1 DNMT3B LINC00689 STAP2 FBXO43 TMEM177 LIPE ASPHD1 ASS1 RGS4 FRMD5 GABRB2 CRB2 TTLL11-IT1 STK32A NAV2 MECR MOV10 CCDC151 PRB1 CCZ1 SULT1B1 KDELR3 HNF1B IQUB	up	*
GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN	0.0070161	0.0317388	0.4070179	0.3462234	1.506275	131	CPS1 DNAJC12 SOX2 SAP30L-AS1 MYBL2 MRPS35 SPPL2B GSDMB CLSTN3 SOX30 STAG3 VASH2 CLSPN CSRNP3 OAZ3 ZNHIT1 EHF BRIP1 OGFOD2 TTC9 PPIL2 PPM1E CTDSP2 CDK12 CLMN UCK2 C1orf112 IGHG1 TNNI2 TMEM120B NRIP2 ALX4 PUS1 SSRP1 DTYMK GNRH2 ESR1	up	*
GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN	0.0011281	0.0074387	0.4550599	-0.2840189	-1.506064	181	ADCY9 PTP4A2 FYN PPP4R1 GFOD1 CTDSP1 TGFBR3 AGPAT4 ZEB2 MAP3K8 TTYH2 STOM ADRB2 SRGN CD58 AGO4 AHNAK TNFSF12 DENND3 HOPX CCL4 PRF1 SMAD7 KLRD1 MATK PIK3R5 IL2RB SH3BP5 BTD TBX21 CST7 TIGIT MBP NKG7 PIK3AP1 ATXN1 DOK2 STK40 PLEKHO2 KAT2B CLEC2B SYT11 PITPNA TMEM184B S100A4 CTSC PDE4A MCOLN2 PIEZO1 SLFN11 MAP4 ITGAL ITGB1 TOR2A MAN1A1 ATP2B4 KATNAL1 CD226 SRXN1 GZMB TNFRSF1B SLAMF7 KLRG1 IL10RA PIK3R3 JAZF1 RALGDS GZMA	down	**
GSE30083_SP2_VS_SP4_THYMOCYTE_DN	0.0011413	0.0075039	0.4550599	-0.2842404	-1.505769	175	FAM167A ST8SIA6 HVCN1 HHEX TMEM150B SPN SNX10 LY86 IBA57 CLEC10A S1PR1 CLCF1 ARSB GM2A CYB561A3 LAIR1 IL18R1 GRN CYP4V2 PPP3CC RHOB EVI2B AHNAK MPEG1 CASP1 RRM2B PDE3B HOPX HPSE PLEK N4BP2L1 DSE S1PR4 SGK1 CTSS SOCS3 IL2RB AQP3 STAT4 IFNGR1 IRF8 FAM43A TBX21 RHOQ RIN2 PEA15 KCNN2 ACADL GEM SELPLG IER5 GIMAP5 ZBTB25 ITGAE	down	**
GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN	0.0013708	0.0087298	0.4550599	-0.2907753	-1.504963	149	EPAS1 CXCL3 IL17RB TIE1 SIK1 CCRL2 MYADM CALCRL NR3C1 SEMA6D LMNA KLF6 GATA3 NR4A1 RB1 RGCC CSRNP1 SORBS1 AFAP1L1 ZFAND5 SLC7A8 STK17B MYO1B CDKN1A DUSP1 PLCD1 PLAC9 RBPJ SLC25A3 AREG CREM KCTD12 GLUD1 JUNB PPP1R15A SKIL LPCAT2 ATP13A3 PTP4A1 CPA3 ISM1 ZCCHC10 IRS2 MYOCD ETS2	down	**
GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN	0.0020338	0.0117443	0.4317077	0.3348240	1.504711	176	ADH1C CDC45 RAB3IP TTK ANLN ASPM PTTG1 CDC6 MCM2 PRC1 XDH PDE9A RANBP1 NUDT1 KIF23 MKI67 TOP2A POLD2 MCM7 MPHOSPH9 CDCA5 KLHDC4 LMNB1 SLC12A7 PFKP BLM DRC1 ASF1B CDK1 PPIC UCK2 BIRC5 ACP6 PSAT1 PDK1 SSX2IP EZH2 NRGN DNMT1 SSRP1 DTYMK GEMIN5 PKP4 CNDP2 CENPK SASS6 PSMB3 RPA1 MRPL41	up	*
GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN	0.0033059	0.0171162	0.4317077	0.3417557	1.504494	146	ENTPD2 CPLX2 SLC6A3 PCDHGB4 GOLGB1 RAB36 DPYSL4 BPHL NUP155 EIF2AK1 GPSM2 SEC61A1 SLC9A3R1 CLIP3 ZKSCAN1 HSF4 PTGDR2 SNAPC4 SLC28A2 ERCC2 NRTN EFCAB11 KRT18 ATP2A1 SUN1 MCAT SSX2IP NF1 SRD5A1 CDK3 CCL21 COG2 DNMBP COPS6 SEC14L2 CLINT1 TFAP4 HMCES KATNB1 RHOBTB1 ANK3 EPCAM MICAL3 ALMS1 ZNF212 STK38 ZNF169 CSNK1G2 ABCF2 CCDC9 BMS1	up	*
GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN	0.0011674	0.0076650	0.4550599	-0.2883064	-1.504308	168	SLPI PNPLA6 ST8SIA6 KLF13 HSD17B11 PDE1B BACH1 MEF2A TMX4 KCNAB1 CNST RAB33B FOXP1 CD37 ITPRIP RAB12 TCP11L2 STK17B LBH RAP1GDS1 KREMEN1 FAM102B HECA SF3B1 ETV3 MITF VPS26A CCR7 PRKCE FRYL IP6K1 RNF146 TTBK2 SPOP ZRANB1 BAZ2B HBP1 FCGRT TAGLN LAT TRAPPC8 BRWD1 CREBBP TTC19 SNX15 PAIP2 RHOT1 C1orf52 SMAD4 HNRNPH1 CBX7	down	**
GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP	0.0009249	0.0062583	0.4772708	-0.2832821	-1.503378	176	KLF13 HVCN1 SPN SLC6A12 LPL LMO2 RASAL2 BMPR2 FXYD2 ALAS1 NFATC3 C11orf94 STARD9 TACC1 RAP1A AHRR IFI30 HLX LCP1 UBE2D3 PTPN12 EFCAB14 CSRNP1 MED11 ST3GAL2 RRM2B PLEKHM3 UHRF1BP1L CTSD LAPTM5 PTPRC SMAD7 PPP2R5C TBC1D4 NCOA1 NRROS HRH1 RHOG RAPGEF1 IDS NOL7 OGFRL1 AGPS AZI2 RUNX3 ATPAF1 ZNF175 AZIN1	down	**
GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP	0.0024496	0.0136547	0.4317077	0.3354912	1.503365	167	FANCI ZNF280B NUDCD3 ALDOC GINS4 NCAPD2 MYL6B DLG1 RPAP1 FRS2 CCDC77 FBF1 TMEM177 SNHG11 SLC45A1 ACSF2 XRCC1 TBC1D8 MGA ZNF605 COQ9 FAHD2A CCT3 KCTD13 SNAPC1 PRPF6 MAD2L2 ZKSCAN5 SMG5 FANCF NFS1 COPS7B SLC22A5 KRI1 LRWD1 NAT9 PTER VPS25 IARS2 TUBG2 ASCC1 BAD UBE2V2 BLCAP MYH3 RCN3 MANBAL PCBD2 GTPBP2 ATOX1 RELL2 POLR1A PRPF3 ARMC10 DTD2 PIGQ ACAD8 MIR600HG C12orf10	up	*
GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP	0.0047152	0.0231580	0.4070179	0.3392885	1.503355	157	SIM2 KRT5 FANCI PBK TTK COL7A1 TYMS CA12 EIF3B GUCA1B CEP55 ITGB4 POLA2 TMEM132A TPCN1 LIPE TRRAP ERAL1 BRD9 CHEK1 GEMIN4 RNF216 NCAPG2 HDGF TCF20 NEIL3 ZNF500 PIAS3 SPG7 ARHGAP32 COG2 CCDC51 TADA3 NSD1 POLR3E LHPP GOSR2 BCL9 MMP16 TSC2 ABCF3 ANAPC2 ERBB2 PNKP CENPE IDUA CDC25B NAT10 FAM222B TRPC4AP ERCC3 ACIN1 ADRA2B GRIP2 DAZAP1 KLK10 TEAD3 RUSC1 DSN1 CNKSR1	up	*
GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_UP	0.0016848	0.0101211	0.4550599	-0.2881735	-1.502732	152	ACE LINC00472 CD44 CBL TGFBR2 SCARF1 LRRFIP2 SH2B3 ADA LMNA MTF1 TMEM74B ADRB2 CLK1 MOAP1 AGO3 SRSF5 YBX3 CLDN5 ACTR3 DCP1A CREM SAR1A ADRA1A ELP5 PLK3 ARHGEF10 DNAJA1 IPO7 CASZ1 GPR3 LMCD1 MSMO1 MLANA RXRA PITPNA AMD1 ARIH1 SP100 MEX3C PKNOX2 TMEM87A DLST P2RX1 NRG1 CNN2 CSF2 AFTPH KLC1 MAPK1 ING1 ZYX ECD CDC42BPB FPR3	down	*
GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_DN	0.0029817	0.0158588	0.4317077	0.3345557	1.501548	174	DEPTOR NUP107 UBE2T PGM2L1 SIX4 POLE ALDH18A1 PMS2 MRPS35 CLPTM1L TTLL4 CEP55 AUNIP RAD54L YEATS2 ORC6 NFYA GAS8 RAD51AP1 RPAP2 BRIP1 CAD PPP5C GLE1 KCNE3 SLC25A13 ANKRD26 LIPT2 RNF150 ABHD4 PLEKHG3 MRPL52 SPTSSA DTYMK GALNT3 PSMD2 NUP85 TIMM13 IARS2 ZCCHC17 RRP9 CACNG8 TDP1 RHOBTB1 SLC1A5 SH3PXD2B CEP152 FARSA SUV39H2 JAKMIP3 CCNA2 HLCS SCOC SNX8 PARP2 MFSD3 CLNS1A FAM120A DFFB NELFB EIF2B1 ADSL IL1RL2 MRPL2 SNHG17 TIMM10 RCC2 GCSH DGKZ IMP3 ZSWIM7 PARP16 SRSF9 PRKAB2 ZNF664 PPM1G BUB3 TRIM28 JKAMP DAGLB DDX31 DVL2 TIMM23 DRG2 DPY30 NAA38 SSNA1 SENP5 GTF2A2 TAZ	up	*
GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP	0.0061491	0.0287785	0.4070179	0.3406349	1.501066	144	TF HKDC1 FUT6 BDH1 JPH3 DGCR9 PBK LCN2 LHB IFT122 EIF2B5 HOXB7 FERMT1 PAH PLS1 ACY1 HNF4G TSGA10 MCM7 ZNF443 KHK C7orf26 PTPN3 ZNF512B ZNF45 EPHA1 PLA2G2A NAV2 IGSF3 SNCAIP GIPC1 LGR5 NFATC4 METTL22 ECEL1 EPB41L4B CCZ1 ZNF76 TFCP2L1 ZNF223 DHX8 TBC1D30 ZSCAN32 SUGP1 ZKSCAN7 TXNL4B YBX2 PRSS22 MAP3K9	up	*
GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN	0.0020560	0.0118545	0.4317077	0.3334038	1.500278	179	TRIP13 GPT2 CCNB1 TBRG4 PHGDH ACAD9 ALDH18A1 ESPL1 SPINT2 ORC1 DTL LIG3 C19orf48 CISD1 GFPT1 QTRT1 PCCB CCT5 COASY FSD1 NSUN2 WDR73 SLC25A39 HSPBP1 DDX56 THOP1 SNX4 ARPC1A TRAP1 POLR1C POFUT1 DNAJA3 LMNB2 SSRP1 ZNF239 MFSD2A GINS2 XPR1 SND1 MAGOHB CCDC137 PFAS VPS25 ORMDL2 CENPM KIAA0100 FAM136A CREB3L2 SLC1A5 SUV39H2 CISD3 DDX54 POLR3B ATOX1 CDK5 RBM19 SMC2 ZBTB32 PCBD1 SFXN4 RRS1 TRUB2 ALKBH2 RNF14 SRM TOMM40 TIMM10 TLCD1 URB2 NETO2 LRP8 RBM8A CCDC86	up	*
GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_UP	0.0069843	0.0316392	0.4070179	0.3471832	1.500064	125	TF PTPRR STC2 HOXB7 PLS1 ACY1 TDRKH TOP3B MYBPC2 KIF2C B3GNTL1 RIPK4 CDC42EP1 GPR135 KHK PTGDR2 RGS4 C7orf26 PTPN3 ZNF512B IGFBP5 NAV2 IGSF3 ZKSCAN5 LGR5 TELO2 TUBG1 MSRB2 EPB41L4B ERBB3 ZNF428 NRXN2 UBXN6 TFCP2L1 METTL2B LPCAT4 DHX8 KPTN DUS2 MYH13 YBX2 PCSK5 PRSS22 MAP3K9 ST20 TACR1 BPNT1 BFSP2 SETD5 WDR55 RNF126	up	*
GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP	0.0012749	0.0082710	0.4550599	-0.2828237	-1.499726	181	HMOX1 TSPAN4 PPARG MIR22HG LY86 FOSL1 TRIB1 GGA2 LMNA NDEL1 TMEM41B SETD3 RHOB MOAP1 AHNAK ACSL3 ZFAND5 SPAG9 RIT1 CDS2 CD302 DUSP1 SLC6A6 DEGS1 PRCP SERTAD2 VAMP3 RYBP BCAR3 PGD SRSF3 JUN IDS STX5 YWHAZ IP6K1 SLC3A2 FOS ATP6V0D1 STRN KIAA0232 JMJD6 MEIS3P1 ATP6V0C PLEKHO2 TSPO ME2 PITPNA CDKN1C ARIH1 JMJD1C DNAJB9 NRG1 GRB10 CREG1 TLK1 RNH1	down	**
GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN	0.0013108	0.0084814	0.4550599	-0.2873155	-1.499138	168	RBP4 SASH1 IL1B FABP4 MIR22HG DDX6 CDC42EP2 SCARF1 COQ7 ANPEP GLS SERPINB9 SRSF2 BAG1 FABP5 LIMS1 THBS1 CCL3 ERP44 NFKB1 ATF3 SELL CCL4 TP53BP2 MARK3 RABGGTB RSRC2 LIN7A HCK CD80 BCAR3 NECAP1 PSMA1 STAT4 SNX29 MN1 JUNB CD83 GYPC ZNF804A IDS LSM1 AGFG1 EHD1 PIK3C3 GEM SRP72 TRAF1 SRSF10 ULK2 NPAT NFKBIA ADORA2A PDE8B ITCH MT2A DNAJB5	down	**
GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP	0.0008911	0.0060979	0.4772708	-0.2842784	-1.498903	173	FFAR4 SIRPB1 GCOM1 GPR15 GATA2 SPN SAMHD1 FCER1A SUSD2 CLEC10A STX11 MARCO IL1RL1 APOD PPP1R15B NAAA HDC SERPINB9 RGCC IL18R1 AKT3 MTHFR ATP10A STAT5A CCL22 SELL KLRD1 EMP3 DDHD1 OASL RGS18 OSBPL9 PCGF5 GYPC PRKCE PXK TMEM192 AGFG1 ICAM2 CPA3 SPOP SMCR8 FPR2 GNB4 LGALS3 TSPO IER5 SETDB2 SEMA4A TIAM1 ESYT1 ACTB KATNA1 CD3G KLRK1 B3GNT2 NRP2	down	**
GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP	0.0029016	0.0155347	0.4317077	-0.2877060	-1.497867	156	KMO SLC12A6 SOX18 PECAM1 FCER1A AQP9 PLEKHA1 WBP4 CD22 DNASE1L3 OLFML2A PBX3 SERPINB9 LAIR1 ADARB1 AGO4 FOXO1 BST1 YBX3 KLF9 MYO15B KCTD20 UXS1 PER1 BTG1 PRCP MITF LRCH1 IFNGR1 MTMR9 OSM ZNF350 SPRY4 XYLT1 EPHA3 VAV3 CCP110 IRS2 AOX1 TPMT ZNF136 APLP2 GRK4 SESN1 INTS6 CXCR4 MFAP5 TTC28 LYST P2RX1 NR3C2 HEBP1 EHD4 ATP6V0A1 EXOG ZBTB16 CHML	down	*
GSE27786_BCELL_VS_ERYTHROBLAST_DN	0.0043069	0.0215215	0.4070179	0.3404892	1.497864	142	PCSK6 FAM83F EPN3 TTF2 NDC80 TFF3 THEM5 ALDH1L1 PLEKHA7 SLC7A9 KIF27 SPPL2B PLEKHS1 C6orf132 SPAG16 GPR182 HOXC6 CHAD B3GNT3 ABCB9 TIMM50 SPATA17 FADS2 FUT2 WWC1 PARD3 CXCL14 RFWD3 TTLL9 SPACA4 VANGL2 LRRC56 EPHB2 SAP30 C15orf41 USP18 RPUSD1 HOXA3 USP21 VWA3A AGMAT HAS1 OSBPL10 SCOC SMPD4 UBXN10 ESPN FUT10 CRYGS HR PNPO ROPN1L GLRX5 MTR DHRS4 AP1B1 IL17RC SIX5 TPPP SYNDIG1L USP50 HHIP ZNF473 ACOX2 TUFT1 GADD45A	up	*
GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP	0.0012814	0.0083018	0.4550599	-0.2841361	-1.497732	172	RAB11FIP1 DENND5A SNX10 MYD88 INPP5A ELMO1 FRAT1 CD22 TGFBR2 TMX4 ZEB2 PBX3 ASH2L SLC25A37 C14orf132 KLF4 PXDC1 SCAF4 ITPK1 HOPX LBH ALOX5AP HLA-DQA1 IL24 TDRD7 HCK ARHGAP17 WASF2 PIKFYVE RABGAP1 TNFRSF10B RASSF2 PPM1F TNFSF13 RUNX3 CD74 ZNF136 ATAD2B TIMM22 IQSEC1 TPT1 SIK3 VSIG10 CD19 CCDC92 TNFSF9 DLST AIM2 IL16 ZFYVE26 PLAG1	down	**
GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP	0.0036278	0.0185465	0.4317077	0.3321018	1.497600	181	TTF2 TBRG4 KIF14 IFT27 GPI TRIB3 UMPS MIS18A GINS4 CISD1 MKI67 STAP2 EEF1E1 DCTPP1 PKMYT1 TADA2A ALDOA MNAT1 HDGF GOT2 STEAP1 RECQL4 EIF6 VBP1 UQCRFS1 TRIM24 CDC23 COA3 DNAJA3 PUS1 DHODH PSME2 MRPL11 TK1 MYBBP1A ASNS POLD1 JTB RAD50 TSTA3 POP7 GMPPA KPTN LSM7 NDUFS7 LSM4 TCERG1 PRIM1 SNRPD2 RFC5 BMS1 GADD45GIP1 NDUFA8 DNPEP CPOX SLC12A2 SMC2 POP4 SF3B2 PWP1 MRPL48 DNM1L COX17 CALU RANGRF GEMIN2 MRPL12 PRPF19 CLPP TOMM40 NCKIPSD CS NIT2 RMI1 REEP4 CALM3 BNIP1 COX6A1	up	*
GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_DN	0.0081104	0.0357266	0.3807304	0.3617239	1.497581	92	MNX1 ONECUT1 BIK FAM24B CHCHD6 SDK2 CATSPERB DAW1 IRX6 C4orf19 AGR2 GUCA1B RSPO4 TRPT1 MST1R MEOX1 C4orf47 GUCY1B2 KIF7 EVC2 NFASC LRFN3 C9orf50 COLEC11 PTN NAGS CENPV RAB3D MYH7B APC2 ME1 TRIP6 TBC1D32	up	*
GSE12366_GC_VS_NAIVE_BCELL_UP	0.0017533	0.0104046	0.4550599	0.3337667	1.497220	173	HELLS BIK BUB1B MND1 CDCA7 GINS1 BAIAP2L1 PLK1 ESPL1 SOX9 GAPDH CCNB2 UHRF1 MCM4 MCM2 TYMS DTL GFPT1 GPER1 MPHOSPH9 CDCA5 PRKDC RAD54L FHOD3 MCM3 RNFT2 CHEK1 HES6 NCAPG2 TMEM106C ASF1B BCAS4 ENPP3 PEG10 RAPGEF5 CCNE1 KIF22 HMGN3 ANP32E AAMP CKAP5 CENPM RPA1 ROMO1 TDP1 DPY19L2 GINS3 CEP152 MCRS1 SLC2A5 CCDC167 PFKM SRP9 CTTN SMC2 BCL6 CENPE CBWD1 SYNE2 MRPS27 UBE2C NCAPD3 NPR2 SMARCB1	up	*
GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN	0.0009736	0.0065515	0.4772708	-0.2817843	-1.496778	177	DAB1 LPIN2 HSD17B11 GPCPD1 BCL2A1 IL1RN HSPE1 UBL3 ADAM17 LMNA LATS2 LITAF SLC7A11 SERPINB9 PPP2R2A RGCC TRAF6 SRGN UBE2D3 TUBB6 CWC22 FABP5 AHNAK HNRNPA3 YBX3 CDIP1 STX3 CDKN1A M6PR KPNA3 ANXA3 MARK3 PDK4 PPP6C STAT4 MAP4K4 EEA1 PIK3R1 CD83 AGFG1 SNX9 HIVEP2 STXBP3 HNRNPA2B1 TGIF1 SLIRP RNF2 RPP30 IL18RAP SERTAD1 RAB5A VPS4B TRAF1 B3GNT2 ANXA11 LDLR GSPT1 DNAJA2 SUGT1 CENPC FTL C6orf62 WAC KCMF1 SMARCA5 WDR26 PDPN GJB2 CFLAR CCNC IRF4 SRXN1 TPST2	down	**
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP	0.0022170	0.0126477	0.4317077	0.3329960	1.496653	178	TRIP13 RUVBL1 RPGRIP1L TIMELESS SCN3A GINS1 STIL MYBL2 PRC1 ORC1 COPB2 MIS18A ZWINT MYL6B PCCB CCT5 CBX3 KIF2C CD2AP RNFT2 TOPBP1 ORC6 MAD2L1 DET1 PON2 TNFRSF21 UCK2 C1orf112 AAGAB GMNN GOT2 FEN1 CBX1 FOCAD PA2G4 CHCHD3 VIPAS39 NINL MRPL11 TCEA1 SPAG1 SND1 CCT7 CDC20 MCM6 TDP1 TCERG1 CFH MSH2 TM7SF3 CCNA2 PRR11 DENR ABHD10 TPGS2 MICU1 NUBPL SMC2 FAIM GMPR2 CENPE SCN9A PAICS SIGMAR1	up	*
GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_UP	0.0051040	0.0247182	0.4070179	0.3354849	1.496352	162	MCM10 E2F8 TRAIP ILDR1 CEP70 CDC6 NNT UMPS CCT6A CLCN2 KIAA0895 RANBP1 TTLL4 TNNT2 PCCB TMEM177 KIF2C TFR2 WDHD1 MRPL3 WDR66 YEATS2 C7orf50 RAD51AP1 SPC24 PKMYT1 IDH2 CKS1B FAHD2A HARS2 KCTD7 ERC2 PSMG3 GIPC1 GRAMD1A ATP7B NDUFA11 YDJC TSNAXIP1 LONP1 KIF22 ZMAT5 SLC22A23 SGSM3 ACSL6 CENPK TNK1 SASS6 ASB6 PLEK2 LSM7 ENOX1 LPIN1 VPS33B GADD45GIP1 GTF3C5 MAPK8IP3 TRIM67 PIGQ NOS3 SFXN2 SRM MRPL2 RASAL1 COL5A1 STARD10 SCUBE3 MLLT3 MMP14	up	*
GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP	0.0014550	0.0091066	0.4550599	-0.2867697	-1.496290	168	SIDT2 SPN LRRC8C RAPGEF2 SAMHD1 USP47 ABCB1 NUMB UBR3 PPP1R15B CYB5A PAG1 TOR1AIP1 EPM2AIP1 RAB14 PTPN21 UHRF1BP1L GAA ZADH2 SCAF4 WDR48 EXOSC8 PEAK1 TM9SF2 PAFAH1B1 NRBF2 STK24 HGSNAT NCKAP1L DCP1A APPL1 NECAP1 CELF1 OSTM1 EPC1 CREB1 MORC3 CGGBP1 TRAPPC10 FAM204A PHF3 TEX14 VAMP4 POLK PLA2G15 SLC43A2 FKBP1A CYB5R4 BRWD1 CEPT1 DOCK10 RORA NABP1 GIMAP4 FEZ2 CBX7 ATP11B ITGAL FAM8A1 ZFYVE1 HP1BP3 CCNT2 MICAL1	down	**
GSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_UP	0.0037955	0.0193227	0.4317077	0.3427174	1.496095	134	CEP72 IGSF9 CDCA7 DAW1 CDK5RAP3 ZNF850 STAP2 ZNF485 P4HTM CLSPN MPHOSPH9 PKM ANKRD13B TOPBP1 ARHGEF38 PIH1D1 ZKSCAN1 HSF4 CNOT3 ZNF32 KCNE3 ZNF789 RNASEH2A TRIM16 COL9A2 TUBA3D SLC4A2 GNAZ ZBTB7B PROX1 TMEM106B SLC52A1 CHTF8 WRNIP1 CENPT RNF215 DPY19L2 PYGO2 NDUFS7 PIP5K1A POLR3E ERGIC3 DDX55 MCRS1 STAT6 ZNF404 ZNF384 ARHGAP5 TP53 RAB25 SBNO2	up	*
GSE3982_NEUTROPHIL_VS_TH1_UP	0.0019598	0.0114214	0.4317077	-0.2868743	-1.495957	152	SLC12A6 PDLIM2 MIR22HG LRRFIP1 MSRA AGTPBP1 DNAJC3 ASAP1 PLXNA2 RAB33B HLX UBE2D3 MCL1 CCNI SORBS1 KLF4 NPR3 SEC24B CD53 NRBF2 MARK3 ARHGDIB PIAS1 RNF141 LTBP2 RAC2 ATP6V0B SNRK BIN2 BTBD7 BAZ2B APLP2 EXOC1 SLC34A2 PARM1 SEMA4A ACAP2 EXD3 MBD5 KCNK7 DOCK4 RAB2A DCUN1D2 CDC14A USP4 MAPK1 HEY1 LRRC2 SCAF11 CAPZA1 SERP1 OCLM WDR26 SETD2	down	*
GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN	0.0007757	0.0054854	0.4772708	-0.2805082	-1.495887	182	ACE LTA4H PTP4A2 BMP2 RUNDC3B BACH1 CDC42EP2 FAM49A IGSF6 ABCB1 TXNIP SLC44A2 RAP1A IFI30 SPIRE1 HLX PAG1 PTPN12 CASP1 PLAUR ST3GAL2 NR1D2 CD53 ELK3 MPC1 IL7R TBC1D4 DEGS1 CD300LB CNOT6L CLN8 ARL6IP5 PHTF2 GLUD1 RAC2 RAPGEF1 GPR183 ENTPD4 NDST1 CDK17 NAPG NIPA2 VAMP4 TEC	down	**
GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_UP	0.0019640	0.0114319	0.4317077	-0.2841914	-1.495731	169	SWAP70 DENND5A SH2D3C CTSW SAMHD1 AQP9 ZEB2 ANXA1 ENTPD1 BTG2 LAIR1 PPP3CA ARHGEF2 PTGIR YBX3 MVB12B SOCS2 TMBIM1 CDKN1A ITGAX VIM AQP4 ID2 TM6SF1 PLEK KLRD1 PDHX SGK1 IL2RB TYROBP IFNGR1 RHOJ ELOVL7 CD7 NKG7 PIK3AP1 DUSP5 CLDND2 LGALS3 NQO2 ACTN2 RGS2 RXRA RBL2 SELPLG ARHGAP18 CTSC KLRK1 LYST SAMSN1 USP48 SMPD1 CSF2 ZYX SSC5D S1PR5 RCBTB2 NFIL3 RPA2 DOCK5 METRNL GZMB MYO1F KLRC1 C15orf48 APOBR EIF4E3 F2RL2 SLAMF7 ANXA6 KLRG1 CAPG CD47 SNAI3 GZMA IQGAP2	down	*
GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN	0.0007802	0.0055035	0.4772708	-0.2831201	-1.495551	174	SEMA6A ACVRL1 OLR1 RAPGEF2 CYP4B1 STX11 CDC42 IL1RN FAM49A ADA MTF1 PRELP ZNF410 LCP1 TXN MAP2K3 KCNMA1 SLC12A4 DENND3 VRK2 GMPR NFKB1 CCL4 DUSP1 ARL4A VAMP5 TP53BP2 SRSF3 CD48 DNAJA1 RCAN1 PPP1R15A WTAP PTGER4 CCR7 CD83 CXCL5 CST7 MSMO1 DUSP5 ANKRD12 KAT2B SOD3 ICAM1 CGRRF1 RTN1 TRAF1 GLUL STK4 BCAT1 NFKBIA LDLR MT2A ABI1 CSF2RB DUSP6 ENDOD1 S100A8 MT1E SLC9A3R2 LAMTOR5 FCGR3A PDPN NR4A3 MSC RNF19B CYP1B1 ADAM19 PLXNC1 CRLF3 SERPING1 IL10RA SQLE MT1G CRYBA1	down	**
GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP	0.0042995	0.0215065	0.4070179	0.3371467	1.495520	156	SAA2 BHMT DOC2A CLGN NIPSNAP1 EFNA4 LAMP5 EBF3 ACAD9 RGS6 ZFP64 SMARCC1 FOXA1 TPBG NUP155 MPHOSPH9 TPCN1 SMYD2 LPIN3 TMEM45A FAM162A ARMC12 TOPBP1 PTGDR2 LINGO1 SRCIN1 DNAH5 TCTE1 SMG5 PUS1 LMNB2 HDHD3 KY ZNF239 METTL22 NUDT16 GRIN3B IFNAR2 NIF3L1 NOL6 CAPRIN2 HMCES LRRK1 POLR3E WDR45B PSMB4 PRMT5 LRRC14 PRSS22 MRPL9 IKZF4 GNE SRCAP TRIB2 GOLGA2 SLC38A4 MRPL20 CEP290 APRT RALGPS2 CHD8 PARP4 CRYZ DCLRE1A ZAP70 UBE3C CRCP SLC44A1 SLC25A35 ZBTB48 C1orf43 RPS10 OPN1SW GLB1L ASPRV1	up	*
GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP	0.0027642	0.0149136	0.4317077	0.3337272	1.495460	167	HELLS DEPDC1 PIF1 BRCA1 RACGAP1 E2F8 ANLN DGCR8 PLK1 ESPL1 UHRF1 MCM4 NCAPD2 IKBKE WDR62 KIF15 CENPL EME1 POLA2 TPR MPHOSPH9 RRM2 WDHD1 GPSM2 CKAP2L PIH1D1 MDM2 ANKRD16 ZCRB1 CDKN2C PLOD2 CENPH TRAP1 DNA2 DYNLL2 TNPO2 GBP5 TEP1 GRAMD1A MAN1B1 PPOX CHTF18 ESCO2 MLEC SLC4A2 ATAD5 GALNT7 CKAP5 DYNC1LI2 UTP20 IL12RB2 ATAD2 RTEL1 TUBGCP4 RAD51 SNRNP70 MAPK8IP3 PRPF3 NCAPD3 RASGRP1 DNM1L THAP3 NCAPH ACIN1 PCGF6	up	*
GSE7460_TCONV_VS_TREG_LN_DN	0.0009698	0.0065353	0.4772708	-0.2812242	-1.495392	185	CXCL3 GPR15 DENND5A ZC3H12C LPXN CCRL2 C3orf70 ABCB1 ENTPD1 MAP3K8 KLF6 CYP4V2 AHNAK AGR3 ST3GAL2 SOCS2 SOCS5 HOPX AXL SHE UBE2B ELK3 MATN2 PEAK1 UBASH3B TBC1D4 CNRIP1 TDRD7 PRKRA PHTF2 KIF13A IL2RB RAB8B ST6GALNAC4 PTGER4 CD83 IRF8 TNFRSF9 DENND4A ZBED5 CD86 ZC3H12D CD81 GABARAPL1 STON1 SERINC3 RXRA BMP2K CCR6 GEM SESN1	down	**
GSE17721_CTRL_VS_POLYIC_4H_BMDC_DN	0.0017298	0.0103278	0.4550599	-0.2851605	-1.495226	166	ZC3H12C CLDND1 SIK1 HCAR2 CAV1 NUDT9 NR3C1 IL1RN MOB1B CCNL1 TXNIP SSTR1 PAG1 ATP10A DAB2 OSTF1 CDKN1A ATF3 CAPZA2 PPP2R5A N4BP1 SPRYD7 CMTM6 TDRD7 PROCR USP25 RAB8B MTMR14 MITF PPP1R15A IRF8 NPR1 BLOC1S6 PIK3AP1 EHD1 GSAP TSC22D1 IFNAR1 ZNF296 PDE4B ETS2 IL18RAP SERTAD1 CEBPD TAB2 ARL14EP G3BP2 FNBP4 KLRK1 TNFSF9	down	*
GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP	0.0062563	0.0292521	0.4070179	0.3370890	1.495125	155	PCSK6 FAM83F GRIA4 KCNK5 EPN3 CP ANLN DGCR8 LMLN FAM169A CUL9 EEF1E1 NUP155 WIPI2 ASPHD1 CCL28 RPAP2 C2CD3 CBX5 CDK1 C1orf112 VANGL2 POLR1C LRRC56 GAL3ST4 UNC45A SNRNP25 TRIO OSBPL3 ACBD4 DNM1 TSSK3 SGSM3 C15orf41 TNK1 SASS6 TUBG2 KRT8 ARVCF GAD1 TCHP STRBP APOBEC2 CCNA2 PRR11 MSS51 RNF123 NME7 CENPE SMPD4 ZMAT2	up	*
GSE6875_TCONV_VS_TREG_DN	0.0051448	0.0248171	0.4070179	0.3382992	1.494984	152	PRR15 RUVBL1 POLQ NOVA1 PPP1R14D DGCR8 CDC25A SLC4A4 CCNF DNAI1 TNNT2 AP4M1 CLHC1 CCT5 WDR3 MPO AKAP1 CHAD BRI3BP PLXNA1 HEBP2 TOPBP1 WNT5B PON1 UQCR11 ATIC GOT2 ACSBG2 ACTR3B RNF207 ETFB ATAD3A RNASEH2A IFI27L2 MZT2B SALL4 TUBA8 MRPL4 SYT1 IQCH ZBTB7B NAGS RRP9 TTC34 EXOSC5 POLR2I LSM4	up	*
GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_DN	0.0064461	0.0299385	0.4070179	0.3473371	1.494401	124	PLAT VWDE HOXB-AS3 IGF2BP3 ZNF280B PTTG1 APOL2 DTL AK8 GPX2 ZNF572 MAP10 APOL1 IL20RB RNFT2 ARHGEF34P PTPN3 C2orf50 RBCK1 IGHG1 ACSBG2 RAB6B RTCB HNRNPA1L2 PSME2 ZNF239 ESCO2 IQCH SND1 HLA-A ZNF202 GMPPA TRIM56 TMEM253 GBP1 TUBA4B OXCT1 ENKUR VPS9D1 DNPEP PTPRF MCF2L2 NOMO3 SH3GL1 FAM219A NLRC5 DYNC1H1 HGD TRAFD1 LOXL1-AS1 BAK1 ARFIP2 BTN3A1 TMEM214 KEAP1 ARHGEF26-AS1	up	*
GSE3982_MAST_CELL_VS_NKCELL_UP	0.0017810	0.0105434	0.4550599	-0.2849855	-1.494308	166	EPAS1 LIPA LYL1 FCER1A RTN3 FOSL1 ALAS1 LAMP1 SIGLEC6 HSPE1 WWC2 MCTP1 LMNA CAMTA1 ABHD6 EPB41L2 SORBS1 TPSG1 ADO DRAM1 SOCS5 CLIC4 ABCC4 GMPR M6PR ARAP3 RPF1 GNAQ RSL24D1 TBC1D4 SNN FRY PPP2CA ESD PPP6C MITF IPO7 ZNF804A MOB1A RBKS PSMD12 LSM6 TSC22D1 UTP3 SERINC3 HSPA2 CHMP3 LRP12 GLUL BCAT1 TIMP3 P2RX1 CAMSAP2 GRB10 EVI5	down	*
GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP	0.0007806	0.0055035	0.4772708	-0.2810543	-1.494283	180	EREG IL1B SIK1 RTN3 AQP9 STX11 ELMO1 TRIB1 IER2 HBEGF PTX3 HNRNPU MCL1 HNRNPA3 BNIP2 VASP CDK9 CTSD LAPTM5 COTL1 P2RY2 CXCL2 DUSP1 ARL4A CARS2 TP53BP2 ACTR2 AREG CREM SGK1 SOCS3 NECAP1 CTSZ GLUD1 TREM1 PLK3 JUNB PPP1R15A BAG5 PABPC4 CD83 RAB8A SPATA2L YWHAZ ATP6V0D1 ADNP2 MFSD10 FOSB TESK2 FPR2 DUSP5 TSPAN14 NPTN PLEKHO2 JUND CXCR4 HNRNPK G3BP2 SCPEP1 ICAM3 GLUL NFKBIA PAK2 SFPQ EHD4 ATP6V0A1 HERPUD1	down	**
GSE17721_LPS_VS_CPG_6H_BMDC_UP	0.0024687	0.0137260	0.4317077	-0.2849753	-1.493996	163	SLC12A6 ADPRH RBMS2 LRRC8C SNX10 SLC10A1 FYN CCRL2 SAMHD1 PRPF38A TLCD2 BFAR FAM122A AKT3 ATP10A MAP2K3 TBX4 STX3 LY96 SEC24B ATL3 GPR85 ARL4A KLRD1 PI4K2A SAR1A PHACTR2 APPL1 HSPA1B TSPYL1 SNRK CDK14 CACYBP CD164 CCR4 DOK3 SERPINB1 KCNN2 TMEM70 ACADL CRY1 GNA13 SMAD2 IQSEC1 UBE2D1 FNBP4 STK4 MAFK KLRK1 TNFSF9 BMI1 SUGT1 TNFSF8 CDKN1B ATP11B	down	*
GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_DN	0.0119198	0.0476012	0.3807304	0.3438399	1.493864	130	ATP10B MUC13 MROH3P GRIK2 FOXA3 SPOCK1 HOXD8 NPAS1 LHB C4orf19 ARHGAP33 MYL6B SYT12 MED12L SYNE4 CACNA1G MSX1 ADM2 PROM2 C2orf72 DDR1 URI1 SPATA6L KXD1 SLC35F3 ELMOD3 ATP7B MAPK13 ZNF239 COLEC11 LRRC20 HLA-A KIAA1549 SLC26A1 TNS4 DNAI2 BTN1A1 DYNC2H1 ZNF563	up	*
GSE20727_CTRL_VS_H2O2_TREATED_DC_UP	0.0009168	0.0062209	0.4772708	-0.2831532	-1.492970	173	RAB11FIP1 SIDT2 PDLIM2 MNDA PTP4A2 PLEKHF2 HEATR5B MEF2A MANBA CD1C ZDHHC2 RNF144B PARVG ABCG1 PTPN12 STAT5A SDCBP KLF4 SLC38A11 ID3 RBMS1 ELMSAN1 SLC6A6 MAPRE2 PI4K2A HCK BTG1 TBC1D5 SERTAD2 CCNY RAB8B CELF1 IFNGR1 GRB2 GTDC1 HOMER1 UVRAG EGLN2 TFEB GSAP CD1D IRS2 CD81 GNA13 CCR6 MOB3B SF1 BLOC1S2 SIK3 ACTB	down	**
GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	0.0034749	0.0179338	0.4317077	0.3325788	1.492675	174	EGLN3 FANCI PBK KIF18B GINS1 RACGAP1 TRAIP POLE SPP1 STIL NUF2 ALDH18A1 CDC6 TFDP2 CCNB2 UMPS TMCC1 TDRKH MAP7 MKI67 TOP2A CPD DPCD RRM2 CDCA5 PASK SPRY1 KNSTRN CKS1B NUSAP1 ASF1B CDK1 DNA2 RNF181 PSAT1 ABHD4 FGFR1OP HSPA4L DGCR6 AKR1E2 KIF22 KY ASNS LCLAT1 CENPK SLFN12 MCM5 CREB3L2 ATAD2 ZNF580 TMEM17 CCNA2 TIGD2 STAB1 LPGAT1 FBXW11 IKZF4 GMPR2 SEPHS1 CISH PPP1R16A NCAPH CD38 METTL4 DSN1 SMYD3 MPZL1 COG6 GCSH MRPS6 TMEM214 ALPK2 TXN2	up	*
GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0012004	0.0078289	0.4550599	-0.2810944	-1.491767	176	KMO GIMAP8 TMOD3 MTMR10 CIR1 TET2 FAM49A UBR3 B3GNT5 UBL3 SERINC1 ACOT2 FOXP1 PRSS12 CLN5 SLC25A37 TIPARP PTPN12 PXDC1 SOCS5 PLBD1 ARHGAP9 ARL4A ADD1 AFF3 STK24 TDRD7 HCK NRROS MYLIP CREBRF SOCS3 TYROBP RCAN1 CCR7 FAM43A LPCAT2 CEBPZ SNRK RNF146 FOXO3 DDX18 CD1D CD81 FCGRT CRY1 VPS39 PLA2G15 TXNDC15 ALDH2 NFKBIA TTC28 LPAR6 GIMAP4 RNF13 FEZ2 SPATA13 FCRL1	down	**
GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN	0.0036094	0.0184909	0.4317077	0.3321566	1.490780	174	DDX11 HJURP ZMYND8 TTK NIPSNAP1 EIF2B5 UMPS CAND1 VILL COQ3 CETP NUDT1 DPY19L2P2 TOP2A PUS7 MRPL3 PASK MCM3 SIDT1 TMEM63A PERP PHB ZNF32 CBX5 URI1 PKD1P1 CMTR1 STEAP1 SYN3 ITPR3 PELP1 LRRC8D COPS7B ZNF544 AGPAT5 DAP3 COPS6 SULT1B1 PFAS TSTA3 LIMA1 KLHL23 IARS2 MRPL24 MRPS33 NOSIP USP21 ADD3 ABCD4 COPZ1 INTS8 DZIP3 CLUAP1 ERBB2 TRIB2 DHRS3 NELFA PWP1 CORO1B CD38 TMEM62 EIF2D NSUN5 TFG RPL36	up	*
GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_UP	0.0014333	0.0089985	0.4550599	-0.2840807	-1.490568	161	CD52 SOWAHC SNX10 PTPRE LYL1 LDB2 CYB5R3 NCF2 PLA2G7 MAN2B1 BMP1 SLC7A7 ENTPD1 CHRNE PPP1R15B BTG2 ANXA5 LCP1 SPI1 EPB41L2 HIF3A FUT7 ZFAND5 VASP NPR3 COTL1 ITGAX CD302 ARHGAP9 CD300C DSTN CLIP4 ANXA3 SLC8A1 RNF149 PDE6B JUN GRB2 RBM22 CD74 NR2C1 SBF2 CD81 RGS2 PDE4B RTN1 SEMA4A MFAP5 TRAF1 KIT MAFK PAK2 ITCH	down	**
GSE45365_NK_CELL_VS_CD11B_DC_UP	0.0063681	0.0296611	0.4070179	0.3437577	1.490493	129	PDE11A MUC16 SRGAP3 PTPRR B3GAT1 TRAIP SP5 ASPHD2 CUL9 MSX2 IDO1 ABCC5 KIF11 SOX11 CYP2W1 BTBD2 C2orf50 SPACA4 CCNJL KCNK12 STEAP3 GDAP1L1 ZNF606 MBD4 ASGR2 PCSK4 GINS2 VIL1 NUDT16 MMP7 CCDC51 PROX1 L3MBTL2 COL26A1 RPUSD1 KRT8 MAB21L3 CHRNA3 VWA3A ZNF212 DTNB ZFP14 SIRT6 TRIM62 PIGL SLC35G1 ASCL2 ZNF619 TMEM63C WDR63 HDAC10 PRR12 ROPN1L ZNF414 DRD4 LZTS2	up	*
GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_DN	0.0019918	0.0115522	0.4317077	0.3317533	1.489991	175	GRIK2 BDH1 NUP107 NEK2 CCDC34 CENPF PAIP1 BRCA1 MRPL46 METTL1 TRAIP ECT2 TPX2 PRC1 AACS TMCC1 ZFP64 TMEM81 COX11 WDR62 BUB1 TMEM177 POC1A WDHD1 AKAP1 KIF11 FANCD2 GPSM2 ANG ABCB6 MTG1 C2CD3 CENPH POLR3K USP42 NLN CBX1 LGR5 ILF2 GBP6 GEMIN5 FZR1 GK5 ATAD5 CENPK PPHLN1 CHCHD1 ZNF428 SLFN12 TDP1 PYGO2 DNAJC21 ADM FAM3C WDR4 RAD51 ARHGAP11A	up	*
GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP	0.0043132	0.0215308	0.4070179	0.3339223	1.488989	163	LEMD1 CEP89 PARPBP PRIM2 BET1 TTK CDK4 ANLN PLK1 AURKB TPX2 FIGNL1 PRC1 MCM8 CAND1 NCAPD2 MAGEF1 RUVBL2 TOP2A YKT6 KIF2C E2F2 C14orf93 ERAL1 GPSM2 TARS2 ASS1 DNAJC9 ORC6 TIMM50 ZMIZ2 EFCAB1 VPS72 EFTUD2 ACBD6 ILF2 C19orf47 NMRAL1 TK1 MGMT MAGOHB TDP1 HAUS6 STK35 INTS8 CCNA2 DENR MRPL55 PDAP1 ABHD10 CLUAP1 ZWILCH PPFIA3 MXD3 VDAC3 SMC2 GLYCTK CDC25B FBXO45 E2F7 C4orf46 SCAF1 SPIDR METTL4 PLK4 RBL1 ZNF771	up	*
GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP	0.0008704	0.0060152	0.4772708	-0.2818655	-1.488924	174	MCOLN1 TSPAN4 LTA4H LPXN SEC22C GTF2I S1PR1 FRAT1 PCYOX1 C1orf21 ACOT2 TTYH2 KANK2 ARL11 FLI1 PER3 DUSP3 MPEG1 KIAA0513 STX3 TLR4 LBH ALOX5AP CD300C MFSD11 PINK1 PEAK1 IL7R MMP19 CREBRF FRY CYB5R1 SNX29 RHOJ IRF8 TPRA1 CELF2 MBP TEC CD81 NQO2 RGS2 MFSD12 SESN1 TIAM1 PIP4K2A GLUL FNIP2 SKI DUSP7 MAN1C1 ZFYVE26 ATP6V0A1 PLAG1 CNR2 BHLHE41 PXMP4 HIPK1 HP1BP3 PTGS1 EXOC6 SGPP1 MAP3K1 ITGA6 CCPG1 DUSP22	down	**
GSE27786_LSK_VS_NEUTROPHIL_UP	0.0029889	0.0158799	0.4317077	0.3322393	1.488793	167	PLEKHA6 BRCA1 GINS1 DGCR8 IFT27 CCT6A TRIM45 EXO1 TMEM177 SAE1 TTLL12 HOOK1 FAM162A THYN1 RAD51AP1 FLNB MRPL36 C12orf75 CENPH ZNF260 ZMIZ2 SLC25A13 MECR METTL3 TRAPPC12 RNF150 ZNF623 MZT2B ST14 LONP1 SLC37A4 LMF1 SLC22A5 GSTK1 TSEN54 ESR1 RAI1 NPRL3 RRP9 C16orf58 MRPL28 MYEF2 LSM4 HAGHL MRPS25 INO80E ZSCAN22 DTNBP1 TRUB1 SHISA2 RAD1 IMMP2L CYB5B ISLR PAQR8 AKAP9 PSMB10 MRPL2 DUS3L GLRX5 POT1 TXN2 NUP214 TUBGCP5 KIF3A PPM1G NDUFA9 TUFT1	up	*
GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP	0.0011348	0.0074711	0.4550599	-0.2803788	-1.488154	178	SLC31A2 ZC3H12C LIPA HCAR2 MYD88 ZCCHC2 ZBTB2 TGFBR2 ACER3 JPH2 ANXA1 PLXNA2 COX18 SERPINB9 NFE2L2 CWC22 FABP5 ZFAND5 MAFG RMDN3 ATF3 HPSE CCL4 IL7R DEGS1 TDRD7 LACC1 NRROS RBPJ SOCS3 OASL SRSF3 ST6GALNAC4 PPP1R15A ENPP4 PCGF5 HSD17B12 CDK14 DDX18 SAV1 TMEM230 NAB1 IFNAR1 CD86 ATP6V0C PLEKHO2 PDE4B PCCA SERTAD1 CDKN1C LRP12	down	**
GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN	0.0071696	0.0322832	0.4070179	0.3354705	1.487946	155	BBOX1 SLCO5A1 SPICE1 KIF20A DGCR5 UCHL1 CIB2 KIF18B TTC39A METTL1 AURKB TPX2 CCNB2 CCNF SPINK1 LIME1 CDT1 EXO1 KCNMB3 TMEM177 POLA2 RAD54L SARS2 IGKV1-5 ZKSCAN1 PKMYT1 WNT5B ASF1B CDK1 GJB3 ANKRD26 PDK1 FER1L4 G6PC3 FAH SLC37A4 TK1 IL15RA IGHM DHRS1 CLINT1 DYNC1LI2 XRCC4 RABEPK LANCL2 GADD45G PYCR1 APOBEC2 ARSA GTF3C5 WDR76 CHPF2 ZNF91 TIMM44 UBE2C COPZ2 DHRS9 ANKRD11 DNAAF1 DHDDS GSTP1 CNKSR1 BAK1 CDC34	up	*
GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN	0.0017250	0.0103248	0.4550599	-0.2937625	-1.487107	135	CPEB2 IL1B CAV1 ADRA1D YPEL5 NR3C1 SLCO2A1 ZBTB2 ZEB2 KLHL30 LATS2 EIF1 C1orf21 AKT3 C3orf62 CASP1 COQ10B NKIRAS1 CCL4 PNRC1 N4BP2L1 FOXN3 PPIL4 AREG DNAJC27 NKD2 NDNF TBC1D12 CD7 EPC2 KLRC2 BAZ2B VAMP4 GNG5 ANKRD12 RNF2 GEM CDC42EP3 THAP6 MAFK CD3G DNAJB9 AIM2	down	*
GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN	0.0016909	0.0101454	0.4550599	-0.2849794	-1.486949	168	EPAS1 IL1A DENND5A PECAM1 GPR65 MIR22HG AKAP7 MYD88 BCL2A1 TMX4 CD36 EIF4A1 SH2B3 CD5 PICALM RGCC IL18R1 SPTBN1 KLF4 SCAF4 SLC25A32 MPC1 C4BPB MAPRE2 HCAR3 KLRB1 TULP2 STAT4 CYCS DNAJA1 MALT1 SNRK KLF2 PSMD12 ZBTB1 TGIF1 MIA3 MAP3K2 NFYC PIM1 CLASP2 GPR18 ICAM1 RLF SP100 SCPEP1 GSPT1 PMAIP1 PPP1CB AFTPH CHP1 NR4A2 ENDOD1 FUS ECD	down	*
GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN	0.0031049	0.0163890	0.4317077	0.3308470	1.486838	176	TRIP13 TBRG4 CDK4 EIF2B5 ALDH18A1 CDC6 PMS2 RUVBL2 NDUFB8 DNPH1 EXO1 CISD1 BUB1 AURKA MCM7 RRM2 ZNHIT1 CHEK1 ORC6 MRPS11 MRPL36 CCT3 POLR3K MRPS2 MRPL17 LARP1 TSPAN31 EZH2 MRPS12 UQCC2 EIF6 EFTUD2 EDEM3 DPP3 SNRPA KIF22 MRPL11 ZSWIM1 MARCKSL1 TIMM13 CPSF4 RPRD1B STOML2 DUS1L MRPS33 CKAP2 HAX1 UNC119B FARSA RER1 USP39 PRPF31 NDUFA8 ACP1 SMC2 RPN1 SNRPC DTD2 MRPL20 NDUFB7 NUP93 COX17 NCAPH LUC7L3 DRG1 MRPL12 CLPP EXOSC10 TOMM40 CDC34 GCSH TIPIN MTHFD2 PFKL ITPA PTCD2 EXOSC7 MRPS7 MRPL35 MRPL13 UGDH RRP1B PRDX2 TARDBP DPY30 PMPCB PLSCR1 GART SSNA1 DDX1 UBE2M	up	*
GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_UP	0.0059970	0.0282022	0.4070179	0.3354501	1.486348	157	SHISA3 BRINP1 CHEK2 ARMC3 CIB2 ZP3 FABP6 DTX3 TMCC1 GON4L AP1G2 SMARCD3 IDO1 PCDHGC4 TPCN1 CCDC58 ZNF786 PERP DDR1 GNPDA1 EFCAB6 SRCIN1 NCAPG TCTN2 NEK5 TNPO2 TCTE1 QPRT HDHD3 ARF5 L1TD1 CCDC146 PEX10 ZBTB45 PLCH2 ZNF446 FBXO36 DUS4L SUOX PATZ1 CEP85 DZIP3 ICK TMEM44 TRAPPC9 LBX2 CTTN TACR1 RHOD ZMAT2 PGPEP1 LRSAM1 CAPN9 NLGN1	up	*
GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN	0.0022643	0.0128423	0.4317077	0.3311067	1.486144	177	FOXM1 SPOCK1 ELOVL6 CHEK2 BUB1B NEK2 CENPF TIMELESS PBK BRCA1 CDK4 PTTG1 ESPL1 CCNB2 RAD54B TYMS RANBP1 KNTC1 BUB1 DPY19L1 AURKA NUP155 APOL1 RRM2 ORC6 BLM PHB ERCC2 CKS1B POLE2 BIRC5 GMNN NCAPG PSMB5 SEC61G QPRT RNASEH2A SNRNP25 FANCG DLGAP5 FAH MRPS34 DBN1 PKP4 SAP30	up	*
GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_UP	0.0070650	0.0319097	0.4070179	0.3360468	1.485981	150	ZMYND8 S100A2 DNAJC12 SLC2A1 COL28A1 NDUFS6 ACAD9 GPI GAPDH PLEKHA7 NME1 SDHA ASCC2 PLTP XXYLT1 ARMC12 LINC00664 COQ9 DDX56 NRTN PON2 DDX51 PAK1 KRT18 DMGDH MCAT GNPNAT1 KCNK12 ANAPC7 NUP205 POLR2H DNMT1 DPP3 WDR53 MTOR PTGES2 HDAC1 CCDC159 COPS6 FAM136A LRRC55 PI4KA LINC00937 CISD3 MRPS25 SLC12A2 ALG1 PIGL DTD2 FAM53A ULBP3 E2F7 MRPS26 TRUB2 EID2 WDR64 UBAP1L CLPP LCMT1 ATRIP NHP2 PMVK NCKIPSD C11orf65	up	*
GSE30083_SP1_VS_SP4_THYMOCYTE_UP	0.0038428	0.0195228	0.4317077	0.3310509	1.485702	172	MUC5B KCNMB2 MEX3A GABRB3 UCHL1 SORD TUBB2B WDR70 CDC25A TDRKH VILL AARS2 SMARCC1 SYTL2 BBS1 CBLC HHAT TMEM132A ABCC5 AKAP1 KLHDC4 REPIN1 SLC45A3 PLOD2 PAK1 PLA2G2A CCT3 ABHD17C TNK2 CTXN1 REEP6 CNOT11 LRRC42 SMO TMEM120B CBX1 LAPTM4B ANKRD45 ALDH7A1 L1TD1 EDARADD MARCKSL1 RPL7L1 CCSER1 WDR35 MARCKS STRBP SERPINI2 ICK WDR4 CAPN10 GTF3C5 TCTEX1D1 F13A1 RBM19 CHL1	up	*
GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP	0.0064867	0.0300697	0.4070179	0.3353623	1.484191	154	TRIP13 BUB1B IGF2BP3 CDCA2 E2F8 GTSE1 SLC27A2 ANLN STIL NUF2 ECT2 TPX2 PRC1 CCNF DTL NCAPD2 HMMR KIF23 MKI67 KIF15 KNTC1 CLSPN CPD MMS22L KIF11 CDC25C LIG1 CD24 TXNDC5 CKAP2L DET1 INCENP CKS1B ASF1B POLE2 CENPH NUP205 ETFB	up	*
GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP	0.0019860	0.0115328	0.4317077	-0.2830446	-1.484131	166	EPAS1 DLC1 PPARG OSBPL1A CD55 PTPRE KCTD9 FYN GPCPD1 SLC39A8 RBM14 RXFP1 TRIB1 HEG1 C12orf76 STARD4 ASAP1 UBL3 RNF125 DACH1 GATA3 ZYG11B EVI2B KIAA0513 UHRF1BP1L CLECL1 CLDN5 CPT1A FAM102B STAT4 RCAN1 GPR183 RNF146 ENPP6 TEX30 ZFYVE9 CTNNAL1 GNAI1 SMAD2 NFU1 DNAJB9 NRP2 NABP1 MIER3 GPALPP1 DMXL2 DUSP6 SVIL FAM13A-AS1 HIPK1 ZNF677	down	*
GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN	0.0018496	0.0109093	0.4550599	-0.2862461	-1.483971	146	SLPI SOSTDC1 MS4A7 GLIPR2 SNX10 DPYSL2 CTSW MYD88 STX11 IGSF6 RBM7 MAN2B1 ENTPD1 C1orf21 ZDHHC2 PBX3 CAV2 NOSTRIN RIT1 CADM1 ATP6V0D2 PLEKHB2 GCA PINK1 C16orf54 GLB1 PHACTR2 CYB5R1 STAT4 RAB31 TBX21 GFPT2 SLC3A2 PKIA GSAP CD6 CD81 STX12 SYT11	down	*
GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_UP	0.0065515	0.0302528	0.4070179	0.3365078	1.483277	148	HABP2 ACY3 TSHZ2 CREB3L4 BCL2L15 STC2 SPATS2 PRKCA TAMM41 CBLC ZNF112 THBS4 RRM2 KISS1R HEBP2 ZKSCAN1 DDR1 CKLF GABRB2 CD300A CCM2 PACSIN1 NARF PLVAP MYO19 KCNH3 INTS7 POFUT1 DLGAP5 S100A16 TUBA8 CHTF18 S100A9 CGREF1 POLD1 TYRO3 PARP9 MARCKSL1 CENPK KLHDC3 NAGS CENPV	up	*
GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0011283	0.0074387	0.4550599	-0.2791394	-1.482729	177	ARHGAP31 TMEM126A PTPRE PPP4R1 MYADM AKAP7 ELMO1 IL1RL1 CD22 PDE2A LATS2 RAP1A FAM89A HSPB1 KLF10 LCP1 TIPARP IL10 ARRB1 ADO GCHFR SHE M6PR TM6SF1 PLEK PPP2R5A PEAK1 VAMP5 UBASH3B ACTR2 SLC25A33 S1PR4 CHDH CD48 NXPE3 ATXN1L GLIPR1 COBLL1 TBX21 RNF146 CD74 CCR4 SERPINB1 TEC LGALS3 STX12 SESN1 IL18	down	**
GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN	0.0024708	0.0137260	0.4317077	-0.2815719	-1.481944	169	RAMP3 OLR1 LTA4H GPR65 CD44 CITED2 IDI1 IL1RN FUCA1 FAM49A SCARF1 RCHY1 CASP9 EDEM1 HSPE1 EIF4A1 HBEGF RAB14 PXDC1 PER2 CDKN1A ITGAX CCND2 PLEKHB2 CD53 ALOX5AP N4BP1 SNX3 ARL6IP5 HCAR3 IL2RB SEC14L1 STAT4 STX7 LYRM1 ZBTB24 NDUFV2 PLCG2 NKG7 DUSP5 NAB1 PIM1 ATXN1 PDE4B ETS2 ARAP2 TNFAIP8 CEP170 PAMR1 TPT1	down	*
GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP	0.0035732	0.0183634	0.4317077	0.3306100	1.481492	167	HELLS MDM1 KCNK5 CEP89 PARPBP PAGR1 GINS1 CDCA2 UHRF1 SLC35E3 EXO1 POC1A BRPF3 MRPL3 TRIM11 BRD9 MRPS11 EEFSEC UQCR11 PSRC1 PPIL2 KIAA0556 ING4 CTDSP2 AAGAB GDPD1 IFT52 RP9 TUBG1 MLF2 TRIM37 DTYMK AGPAT5 LRWD1 KDM3B CCT7 LSM14B ZNF841 CKAP5 BRD8 RPA1 BAD WDR83 CKAP2 POLR2I MRPL51 CREB3L2 WDR27 HDLBP TTC12 SCNM1 DOHH TRAK1 MXD3 PGPEP1 SBNO2 RANBP3	up	*
GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_DN	0.0013184	0.0085006	0.4550599	-0.2791340	-1.481364	176	KLF13 HHEX QKI PLEKHA1 CIR1 HMGCR FXYD2 PDCL MCTP1 RAP1A C1orf21 ZBTB8A CCNI AGO4 MTMR6 TCP11L2 CPVL LEPROTL1 ALOX5AP N4BP2L1 ZDHHC20 STK24 BTG1 FRY CCNY SNAP23 HECA ARL5B STAT4 ZNF597 RNF146 YPEL2 ING3 ZFAND6 TBRG1 KANSL2 CXCR4 SSH2 TBCEL ACADM PAIP2 MT2A IL16 RSU1 HERPUD1 NCF1 FAR1 MT1E PIAS2 WAC DR1 RAB1A UFSP2 ANKRD44 IVNS1ABP ZCCHC14 FAM107B	down	**
GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0015336	0.0095182	0.4550599	-0.2795597	-1.480972	175	OLR1 MCOLN1 CLDND1 INSIG1 QKI TBC1D2 HPS5 EDEM1 B3GNT5 BZW1 NR4A1 PDE4D DIABLO ZMIZ1 ATP6V1D MAFG SPAG9 GGTLC1 CXCL2 PLEKHB2 ADIPOR2 FKBP15 SNN GPBP1 RBPJ HCAR3 RYBP DDHD1 RAB8B HCST ARL5B STAT4 SH3BP5 NSMCE2 MALT1 SIGLEC15 REL RBKS RUNX3 SAV1 ZBTB1 CTNNAL1 GALC CRY1 ZNF267 ICAM1 TNFAIP8 SLC31A1 ARHGAP18 TXNDC11 G3BP2	down	**
GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_DN	0.0026678	0.0145712	0.4317077	0.3297011	1.479835	177	PHGDH E2F8 HILPDA NABP2 MCM4 EIF3B MYL6B CISD1 KIF15 POLD2 MCM7 TTLL12 EMG1 ORC6 MRPS30 ALDOA ALG3 MNAT1 DDX56 STX18 MRPS2 PSAT1 NEIL3 MRPS12 ETFB SNRPE RTCB POLR2H DPP3 TUBG1 PDCD11 PSME2 TUBA3D MRPL52 DPH2 CLTA NOC2L STOML2 IARS2 HMGA1 THOC5 CLUH C1orf109 GINS3 VCAM1 AATF POLR2I PDIA4 LSM4 ATAD2 ALG8 PRIM1 DCPS PDAP1 WDR77 HK2 GADD45GIP1 ZWILCH UQCRQ PWP1 NAT10 CALU PARP2 UTP18 PRPF19 RWDD2B FASTKD3 NHP2 URB2 DDX49 SMC4 GTPBP4 XRCC6 PSMD8 PPM1G DNAJC2 PMM2 RPSA CLPB RAC1	up	*
GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP	0.0016486	0.0099652	0.4550599	-0.2825607	-1.479445	160	EPAS1 SLPI FCN1 ADTRP FABP4 LTA4H CYP27A1 LYVE1 BTNL9 THBD SEC22C GAS6 TRIB1 PDE2A ANXA1 MCTP1 LATS2 DACH1 NR4A1 EPM2AIP1 PDE4D TMEM38B MEFV MARVELD1 PTPRC ARHGAP9 DUSP1 CD300C DSTN BACE1 S1PR4 HCST HK3 OSM MAPK4 FOSB TFEB SERPINB1 ADPGK ANKRD12 ABI3BP IFNLR1	down	**
GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN	0.0015860	0.0096590	0.4550599	-0.2791667	-1.478891	175	SEMA6B SC5D CLIC3 SECISBP2L PTPRE RASAL2 CAV1 CITED2 MEF2A MARCO IL1RN IGSF6 IL23A CCNL1 NUMB RBM7 TNFRSF8 CLCF1 SBDS NDUFAF7 SERINC1 NDEL1 TFEC BTG3 BNIP2 PAFAH1B1 SPRYD7 MAFF SRF RPS6KA2 MYLIP ETF1 FLT1 WASF2 SYNPO2 INO80C HSD17B13 SOCS3 SNAP23 PLEKHA3 MTMR14 HSPA1B GRASP LGI4	down	**
GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN	0.0034623	0.0178878	0.4317077	0.3289221	1.478187	176	NMNAT3 METTL1 GTSE1 ALDH18A1 WDR70 TRIB3 XPOT SIMC1 NOP9 QTRT1 SLC29A2 PDCD5 MRPL3 AIMP2 FAM162A AHCY DCTPP1 PRMT6 PHB ALG3 THOP1 HDGF ATIC KIF2A DHX33 GNPNAT1 NUP205 POLR1C DYNLL2 MYO19 GEMIN5 MAGOHB COPS6 GEMIN6 PPHLN1 RPL7L1 PIGU SURF2 SNRPD1 CLUH HAX1 DUS4L RCC1 SLC1A5 MARCKS NEFH ALG8 BANF1 WDR77 PRPF31 LPIN1 SUPT3H PPIA TBL3 FAM185A PPP1R14B CALU PMEPA1 WDR55 UTP18 CLPP HINT1 TIMM10 NHP2 GLRX5 NPM1	up	*
GSE3039_NKT_CELL_VS_B2_BCELL_DN	0.0016273	0.0098486	0.4550599	-0.2802424	-1.477208	172	CXCL3 IL1B EMCN HCAR2 CCRL2 LDB2 CAV1 FOSL1 AQP9 SLC15A3 SCN5A B3GNT5 EMILIN2 CRTAM ZMIZ1 CPED1 CSRNP1 SORBS1 DAB2 KLF7 CDKN1A RBMS1 CCL4 PNRC1 ELK3 SMAD7 LYAR IL7R TP53BP2 MAFF PROCR SLC25A33 RBP7 CD80 RNF149 ADRA1A TREM1 APBB2 WTAP STX7 PCGF5 TEC IRS2 SOD2 LGALS3 BRI3 ETS2 ARPP19 SERTAD1 EPHA2 MAFK EDN1 SKI CYTH1	down	**
GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP	0.0073148	0.0328458	0.4070179	0.3337407	1.477015	154	C1QTNF6 NUDCD3 SDK2 CDK4 SPP1 SAYSD1 SFXN1 KIAA0895 SHMT2 AP1G2 LMLN LDHB BZW2 CUL9 TSGA10 TIMD4 HAVCR1 FANCD2 MCCC2 ANKRD16 FNTB KLHL3 RECQL5 TRAP1 ANKRD26 NLN GAL3ST4 NET1 MPI CCNE1 AKR1E2 ATP6V0E2 FHIT UBE3D ACBD4 L1TD1 TCEA2 SULT1B1 PFAS ABCA7 NOSIP ZNF563 DPH5 HOOK2 METAP1D PAICS RANBP3 TLR5 CDC25B SFXN5 UBTF NAT10 MRPS26 NELL2 PRKAR1B F5 XPO6 RPL23A LRRN1 PPARGC1B PTPRK PRPF19 PNPO ECE1 TCEA3 PPA1 OLFM2 LRPPRC	up	*
GSE22033_WT_VS_PPARG_KO_MEF_DN	0.0069106	0.0315249	0.4070179	0.3310375	1.476515	162	DEPTOR BUB1B APOLD1 HOXB6 GGCT NDC80 FLAD1 TTC26 ECT2 PRC1 GRB7 XRCC2 GALNT10 RUNDC3A AOC1 KIF23 CEP55 BUB1 EEF1E1 MPHOSPH9 WDHD1 HOXC6 PTGDR2 MEA1 CDK1 SPATA6L SNRPE ABHD4 CHCHD3 NET1 CEP63 NFASC PLEKHG3 TK1 SPAG1 ZNF814 POLB PTER ZNF76 ZNF248 TBCA MRPL41 TDP1 CHRNA3	up	*
GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN	0.0035070	0.0180612	0.4317077	0.3285080	1.476326	176	KCNK5 BDH1 GPT2 SLC2A1 TBRG4 TRIB3 STC2 EIF3B CAND1 XPOT ZNF608 CLPTM1L NLE1 EEF1E1 POLD2 SMYD2 HOOK1 SMYD5 C7orf50 FBL ZNF507 PHB SPRY1 GEMIN4 ZCRB1 EXOSC2 UCK2 CCT3 ATIC LARP1 ATAD3A NOP2 YDJC DNAJA3 SNRPA MYBBP1A MFSD2A NOC2L ASNS SND1 CNDP2 PPHLN1 ACLY BCL2L1 PRMT1 NOC4L GADD45G DPH5 DDX54 PRPF31 HK2 BMS1 FARSB ZMYND19 ERGIC1 FAM118B MTHFD1 CISH HEMK1 NSUN5 SRM UTP18 ADSL SNHG17 NHP2 HSD17B7 GCSH SHMT1 LRP8 CCDC86 PC MTHFD2 EBNA1BP2 CTPS1 CDCA7L SLC4A7 EXOSC7	up	*
GSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP	0.0032430	0.0168440	0.4317077	-0.2816872	-1.476320	159	LPIN2 PTP4A2 PTPRE TTC7B FYN SNX32 GFOD1 DDX6 CRY2 YPEL5 CD22 ZEB2 ACOXL SEMA6D UBR3 CYP17A1 ENTPD1 CHRNE PPP3CA CTSD HPSE KLRD1 PEAK1 CRIM1 NCOA1 CREBRF VAMP3 NDNF RAPGEF1 PTGER4 FRYL PKD2 NKG7 PIK3AP1 GSAP DCAF5 PHLPP2 RXRA HACE1 ICAM1 ARAP2 IL18RAP	down	*
GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_DN	0.0022447	0.0127461	0.4317077	0.3291066	1.476316	173	KIF1A C1GALT1 BDH1 GPT2 TOMM34 GPI COX6B2 LIME1 NUB1 C5orf34 BTRC COPG1 RFXANK NUP155 LIPE WIPI2 ZNF146 LMNB1 TRIM11 SIDT1 PPP5C COMMD4 NAA40 ALDOA EDN2 PPIL2 SUPT5H SPATA6L RNF181 GNPNAT1 LRRC42 ELMOD3 UBE2Q1 BCL2L12 PPME1 KLHDC3 EFHC1 DYNC1LI2 MED24 ANKRA2 CYP2D6 HMCES KATNB1 PLEKHN1 ECH1 INO80E PNKP NEIL1 SIGMAR1 NPR2 TMEM38A SMARCB1 DDB2 TTLL5 APEH KCNJ15 VPS18 DHDDS NELFB NIT1 TM9SF1 ZNF414 CCS CMTM3 CHKB CCDC65 METTL17 TNFRSF11B LAG3 TMEM183A CHCHD5 ACADS DCTN5 FBXO2 DECR2 RANBP17 PRKCSH GALT STAU1 GIGYF2 WRN GPS1	up	*
GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN	0.0016529	0.0099789	0.4550599	-0.2800633	-1.476264	172	GPR15 HHEX SOWAHC ZC3H12C CLDND1 EGR2 CCRL2 BMPR2 SLC15A3 STX11 IL1RL1 BCL2A1 SEMA6D ZDHHC2 FAM89A MAP3K8 LITAF SRGN SYNPO KLF4 DRAM1 TMBIM1 ITIH5 HOPX HPSE ATP6V0D2 SHE PLEKHB2 ACTG2 CD80 NSMAF RAB8B EEA1 HSPA13 PTGER2 TNFRSF9 SNX9 RIN2 GSAP TSC22D1 ZC3H12D PDCD1 GABARAPL1 ACADL CCR6 ICAM1 IL18RAP ITPRIPL2 ITGAE S100A4 TMEM87A MMD SAMSN1 EHD4 FCRL1 EXPH5 NR4A2 ENDOD1 NDFIP1 ATP2B4 SKAP2 PPFIBP1 GJB2 TTC39B CASP3 GZMB FAM111A EBI3	down	**
GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP	0.0024708	0.0137260	0.4317077	-0.2816499	-1.475829	165	PDLIM2 LYL1 AATK AKAP7 MSRA KBTBD3 DSCAML1 TACC1 CYB561A3 RAB14 FBXO8 KDSR FABP5 SCP2 NOSTRIN ACSL3 KLF9 DAB2 STK17B TPP1 FMNL3 LAPTM5 MARVELD1 TEF ARHGAP9 FRMD4A MBD2 SLC6A6 CNOT6L GZF1 CTSS GLUD1 OSBPL9 MTMR9 PALM SNX2 ATXN1L	down	*
GSE3982_EOSINOPHIL_VS_TH2_UP	0.0032430	0.0168440	0.4317077	-0.2815399	-1.475548	159	PECAM1 CD55 PTPRE LRRFIP1 KL CD44 PLEKHF2 DDX6 MYD88 MEF2A BCL2A1 FUCA1 TRIB1 ANXA1 TM2D3 EIF1 RAB33B LITAF CAMTA1 NFE2L2 CLK1 MTHFR ARRB1 BIRC2 PTAFR ZFAND5 SMNDC1 RAB6A BTG1 TBC1D5 HCAR3 PSEN1 INPP5B ZNF835 HK3 PPM1F CALM1 TNFSF13 VAV3 GSAP AP1G1 KIAA0232 CES3 CYB5R4 BRWD1 KIT PTEN GRB10 CREG1 CNN2 C1orf115 RABGEF1 CHP1 C5AR2 CNR2 SVIL CLOCK	down	*
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP	0.0008317	0.0058222	0.4772708	-0.2772363	-1.475420	184	DPYSL2 SIK1 RTN3 QKI YPEL5 SPCS3 ANXA5 KLF10 HNRNPU FLI1 HNRNPA3 BNIP2 YBX3 KLF9 KLF11 OSTF1 STK17B LAPTM5 COTL1 ATF3 EPS15 MBD2 MAFF AKIRIN1 SEC31A ACTR2 CREM JUN GLUD1 JUNB WTAP PIK3R1 PABPC4 CXCL5 YWHAZ ADNP2 AGPS PTP4A1 USP7 NAPG HNRNPD AZIN1 TESK2 FEM1B DUSP5 TERF2IP TOB1 NPTN HAUS3 IER5 SEC63 CXCR4 ILKAP G3BP2 SCPEP1 GLUL NFKBIA RNF38 PAK2 PTEN DAZAP2 SFPQ DUT ATF4 DNAJA2 PPP1CB	down	**
GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP	0.0023483	0.0131395	0.4317077	0.3282961	1.474464	175	RUVBL1 CPSF6 MND1 PBK GINS1 CEP70 E2F3 SLC35E3 MYBL2 CLCN2 KIAA0895 HAUS5 EXO1 NUP155 TMEM132A CLSPN LIG1 ORC6 CENPO FADS2 MGAT4B SLC25A10 CCDC40 DHRS13 ZNF229 NCAPG2 TMEM106C ANAPC5 CENPH ARPC1A ABHD17C SLC25A13 ANKRD26 ETFB ATAD3A UQCC2 SPEF1 TELO2 ILF2 TRIM24 NADK2 SNRPA DTYMK GINS2 C12orf73 PSMD2 MAGOHB RAD50 PFAS STOML2 ACLY ASRGL1 MCM5 SNRPD1 HAX1 AATF	up	*
GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP	0.0019531	0.0113955	0.4550599	-0.2825497	-1.474271	168	CXCL3 ZC3H12C F2RL3 CLDND1 CD44 CITED2 FOSL1 IDI1 HMGCR BCL2A1 TEX2 NUMB HBEGF EIF1 SERPINB9 SRGN IL10 CFD SLC12A4 RBMS1 CCND2 M6PR SH2D2A ACTG2 CLN8 BTG1 AREG IL6 ST6GALNAC4 EEA1 PRKCE HSD17B12 AGFG1 MSMO1 MAPK8 TGFB1 MIA3 TBRG1 KCNA3 CCR1 ADPGK SOD3 GEM TRAF1 PALD1 FDFT1 LDLR FNBP1 PIM3 DUSP6 HMGCS1 CYP51A1 IL5 TES PAXBP1 FNDC3A ATF6 PLA2G5 CFLAR CCNC TTC39B CASP3 EMP1 KLRG1 CYTIP SQLE SRP19 NRAS ANKRD17 PTPN22 MAPK6	down	*
GSE20715_0H_VS_24H_OZONE_LUNG_UP	0.0010896	0.0072622	0.4550599	-0.2790847	-1.474235	174	PECAM1 USHBP1 EMP2 TRPV2 CDH5 FIG4 LMO2 TMOD3 CYB5R3 YPEL5 TLCD2 CD36 TBX2 CLEC7A CSRP1 FOXP1 ADRB1 ARHGEF2 PDGFA PPT1 FMNL3 PTPRC SELL CD53 ELK3 SLC6A6 TANC1 ARHGDIB TGFB2 SERTAD2 MYLIP DCTN6 HCST ETS1 RAC2 TYROBP SNX2 PTGER2 CD7 RALB PLCG2 ICAM2 ADPRM SERPINB1 CD6 GNB4 BAG6 RGS2 ARAP2 RNF138 EPB41L5 SCN7A RTN1 CXCR4 CD19 CD3G THEMIS2 NRP2	down	**
GSE557_WT_VS_CIITA_KO_DC_DN	0.0013843	0.0087734	0.4550599	-0.2774423	-1.473959	179	SLPI HVCN1 GLIPR2 CPEB2 LRRC8C STX11 C3orf70 GAS6 TRIB1 RFTN1 ARHGAP29 ASAP1 RASGRP4 LITAF TTYH2 PPP2R2A NDEL1 SRGN DUSP3 CCL22 SORBS1 COQ10B STK17B ERP44 PLEK RSRC2 MAPRE2 NCOA1 LIN54 EMP3 IL2RB SH3BP5 HIC1 DUSP8 SKIL TBX21 ING3 UBXN2A VAMP4 DUSP5 PDLIM1 BRI3 FCGRT GNA13 RGS2 PLEKHO2 IFNLR1 SYT11 HSPA2 SERTAD1 EPN2 RIPK2 ARIH1 ITGAE SCPEP1 VSIG10	down	**
GSE3982_MAST_CELL_VS_NEUTROPHIL_DN	0.0032917	0.0170609	0.4317077	-0.2811343	-1.473422	159	SLC31A2 SEMA6A SLC12A6 DENND5A MIR22HG LRRFIP1 LINC00472 SH2D3C CDC42EP2 C5AR1 SLC15A3 NEDD9 SLC11A1 ASAP1 SERINC1 ADIPOR1 ZEB1 SPI1 HERC3 PTAFR UHRF1BP1L VASP ARNTL NPR3 SPAG9 ARAP3 EVI2A GNAQ MARK3 PRCP S1PR4 AQP3 TYROBP JUNB ZNF407 IP6K1 ACSL1 MBP AOX1 PIM1 KCNA3 PPIG KAT2B SELPLG RLF XKR8 MARC1 KCNK7 JMJD1C ZNF165 DAZAP2	down	*
GSE14415_INDUCED_TREG_VS_TCONV_DN	0.0023490	0.0131395	0.4317077	-0.2841948	-1.473337	146	CD55 ST6GALNAC3 SMIM12 OTUD1 YPEL5 FAM49A B3GNT5 LATS2 CHMP1B FOXP1 PRSS12 ADRB2 SPRY2 PPP1R13B CRTAM PPP3CC PSTK TCP11L2 PLEKHM3 KLF7 NR1D2 CCND2 DNTTIP2 IL7R CRIM1 MYLIP GABARAPL2 MAML2 SNX29 JUNB ELOVL7 BAG5 FOXO3 KLRC2 ZRANB1 PIK3C3 TBRG1 MICU3 IQSEC1 GIMAP5 ZBTB25 TDRP TRAF1 MBD5 NHLRC3 FOXJ2	down	*
GSE3982_BCELL_VS_BASOPHIL_DN	0.0019793	0.0115072	0.4317077	-0.2823042	-1.472990	168	ABHD5 SLC12A6 RTN3 CD9 FUCA1 DDO PILRA DPEP2 SERINC1 PBX3 NLK SIRPA UBE2D3 CST3 FBXL5 BST1 FAM124B RNFT1 DRAM1 MAP1LC3B DENND3 MYRIP TLR4 DUSP1 SMAD7 ADIPOR2 PPP2R5A CRIM1 ACTR2 FRY ELF1 NECAP1 RAB31 BMP3 GSTO1 PSTPIP2 RASSF2 CST7 UBB PTP4A1 MBP FOXO3 BIN2 CHPT1 ITGA9 GLRA3 TOB1 SERINC3 ETS2 SELPLG WDR1 TPT1 LRP12 PLGRKT GLUL CD3G ARPC5 FOXJ2 C21orf91 DAZAP2 GRB10 CREG1 LPAR6	down	*
GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN	0.0011732	0.0076931	0.4550599	-0.2793388	-1.472858	173	ACP5 GCOM1 ST8SIA6 DENND5A HVCN1 PLA2G10 ST3GAL6 SFR1 S1PR1 TXNIP ANXA1 CD5 HBEGF LMNA ENTPD1 LAIR1 AKT3 LRP4 SOCS2 PDE8A HOPX SHE ARHGAP9 KLRD1 MATN2 FXYD7 IL7R PIK3R5 ADD1 FAM102B S1PR4 DCTN6 RHOBTB2 PIK3R1 OSM GRASP TBX21 KLF2 NKG7 IFNAR1 FCGRT ADPGK CRY1 IL18 TDRP DOCK10 KLRK1 KIF1B C21orf91 USP48 ARHGEF18 NCF1 FAM53B MTSS1 TES RCBTB2 ITGA6 FAM78A DUSP22 CD226 CFLAR IRF4 GZMB TPST2	down	**
GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN	0.0040430	0.0204333	0.4070179	0.3270549	1.472598	180	TRIP13 HELLS CPSF6 GGCT PBK NDC80 TTK GINS1 CDCA8 MCM4 MCM2 ALDOC DTL ZWINT CCT2 KIF15 MRPL15 TOP2A RRM2 FSD1 KIF11 ORC6 MAD2L1 AHCY DCTPP1 BLM CKS1B NUSAP1 TMEM106C CDK1 POLE2 GMNN SNAPC1 PSMB5 FEN1 RECQL4 PA2G4 RNASEH2A ATP9A SSRP1 GINS2 KIF20B CCT7 MCM6 PPCDC SNRPD1 PDIA4 PRMT5 PYCR1 MSH2 CCNA2 VDAC1 GTF3C5 CPOX SMC2 LIF MTHFD1 ENO1 COX17 CALU NCAPH CD38	up	*
GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN	0.0017298	0.0103278	0.4550599	-0.2793458	-1.472482	172	ACP5 SIDT2 SWAP70 PECAM1 HHEX CAT COQ2 LY86 LMO2 SLC15A3 HPS5 NUMB GM2A MS4A1 GNG7 RHOB TBC1D9 ADO PIP5K1B YBX3 PAPSS1 ADD1 ARHGAP17 PKIG HESX1 JUN RAB31 STX7 IRF8 COBLL1 CDK14 PLCG2 CD74 SAV1 TFEB TCF4 CD1D PDLIM1 TMEM70 BMP2K OPN3 PARM1 SPIB ALDH2 SCPEP1 METTL7A CEPT1 LYST P2RX1 ZNF165 BANK1 RABGEF1 CTSH BHLHE41 ZNF106 ING1 S100A8 CD79B MAP4K2 PAX5	down	*
GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN	0.0054323	0.0259849	0.4070179	0.3277107	1.472180	171	HELLS HJURP CDC45 MCM10 PMFBP1 DEPTOR UBE2T PRIM2 SORD POLE PLK1 CDCA8 CDC6 TPX2 CCNB2 UHRF1 MCM4 TYMS CDC25A PRC1 DTL MIS18A LSM5 MELK KIF23 CEP55 MKI67 CENPW POC1A CLSPN RRM2 MCM3 LMNB1 IDH2 PARP1 PPIL1 NCAPG2 ASF1B PAK1 CDK1 BIRC5 STEAP3 TNRC18 TACC3 ADAM28 GINS2 PRMT7 LCLAT1 MAGOHB L3MBTL2 ZNF502	up	*
GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN	0.0014370	0.0090104	0.4550599	-0.2772744	-1.471495	176	NUP54 CLDND1 BACH1 MYD88 NR3C1 MAP3K8 LITAF TRAF6 TIPARP FBXL5 TIMM10B CASP1 DAB2 ZFAND5 SOCS2 RMDN3 FAM49B NFKB1 SELP CCL4 DNTTIP2 AFF1 RNF149 INPP5B JUN ST6GALNAC4 JAK1 CD83 IRF8 PCGF5 UNC13B AGFG1 PELI1 DCK TEC CD86 PIM1 CCR1 STX12 BMP2K SERTAD1 CEBPD HSPA8 NFKBIA MCOLN2 TNFSF9 MT2A CSF2RB RBMXL1 UBXN8 ZFP36 MT1E IRF1 CUL2 DR1 FNDC3A ATF6 NFKBIZ RNF19B DCAF13 PNP ANKRD17 NOP58 FGL2 ZNF281 GAB1 ID1 PTPN1 TGFBI CCR5 RIOK3 JAK2 IFIT2 UGCG ST3GAL4 GCNT2 MAP3K3 BUD31 IL15 SLC41A1 TRPC1 STAT3 IL17RA DDX24 NAMPT LCP2 YWHAG LYN	down	**
GSE25087_TREG_VS_TCONV_FETUS_UP	0.0012117	0.0078922	0.4550599	-0.2790735	-1.471460	173	RAB11FIP1 EPAS1 FBP1 SNX10 RDX DPYSL2 CLDND1 BTNL9 PPP4R1 EOGT TRIB1 STARD4 B3GNT5 ENTPD1 SERP2 TNIP3 SERINC1 MAP3K8 LRP4 AGO4 KLF9 KLF11 SOCS2 ARAP3 PRF1 CMTM6 IL2RB C2CD2 PNPLA8 CACYBP TNFSF13 PKD2 PIK3AP1 LRRC32 IRS2 PIM1 APLP2 LGALS3 KAT2B MBNL1 CCR6 MIR155HG CALHM2 RAB5A TAB2 RBMS3 NEK3 KIT TMEM87A MMD SAMSN1 NABP1 SPOPL TOX2 EVI5 FNBP1 C5 ITGAL ITGB1 ATP1B1 HLA-DRB1 PLN KCMF1 SGPP1 RAD21	down	**
GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP	0.0055022	0.0262297	0.4070179	0.3262975	1.471426	181	SPICE1 KIF20A PKP2 UBE2T KIF18B SORD LYPD6B IFT27 TFDP2 NWD1 CCNF MAP2K6 GINS4 TRIM45 GOLPH3L HMMR KCNN4 PAFAH1B3 CENPL AURKA KIF2C CDCA5 PEX6 LETMD1 KIF3C RPAP2 KNSTRN CDKN2C TMEM106C ZNF260 FAM114A1 GMNN RNF181 DDT RNASEH2A VIPAS39 NADK2 DHX40 KIF22 SLC37A4 ZSWIM3 C15orf41 CEP128 HLA-A ACBD5 KLHL32 ALKBH4 KIF21B CYP2S1 ADD3 GLO1 STK38 SHCBP1 ZNF436 NBR1 MTIF3 MRPL9 NME7 MXD3 BCL6 PAICS TTC9C TMEM38A RASGEF1A	up	*
GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP	0.0013866	0.0087734	0.4550599	-0.2769354	-1.471021	177	CD300LF RAMP2 PDE1B CCRL2 BACH1 VAMP2 STARD4 ATP2B1 EMILIN2 LITAF NDEL1 MAP2K3 FABP5 ZFAND5 ATP6V1D MYO1B SPAG9 LAPTM5 IRAK2 FRMD4A ELMSAN1 HLA-DQA1 RBM39 RBPJ CABLES1 HECA FOXN2 PTGER4 GPR183 FAM43A REL TSPYL1 RGS13 ATP6V0D1 RHOQ PIK3AP1 TGFB1 PEA15 DCK NAB1 CD86 IRS2 RGS2 LAT WDR1 INO80 UBE2D1 TMEM184B LYSMD3 MAFK THRAP3 SNAP29 SAMSN1 PPP1CB CBX7 ATP6V0A1 ZNF800 NR4A2 FTL KMT2E	down	**
GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN	0.0010714	0.0071503	0.4550599	-0.2792621	-1.469981	170	SLC31A2 SASH1 IL1B FIG4 CCRL2 CDC42EP2 BCL2A1 TRIB1 EDEM1 EIF1 MTF1 LITAF ZNF410 SPTBN1 TXN MCL1 EPB41L2 STAT5A PTAFR CEBPA CDKN1A RBMS1 RRP8 PLEK N4BP2L1 VAMP5 SERTAD2 IL6 SOCS3 JUN STAT4 CTSZ JUNB PTGER4 CD83 IRF8 DENND4A RALB UBB HIVEP2 IRF5 JMJD6 DUSP5 PIM1 MR1 GEM ICAM1 TRAF1 TNFSF9 NRP2 DNAJA2 PMAIP1 SMPD1 C1QB ANKS1A EYA3 ZFP36 ATP1B1 CD69 LAMP3 MAN1A1 IRF1	down	**
GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0026740	0.0145889	0.4317077	-0.2804706	-1.469650	165	KLF13 HHEX MBOAT2 HMGCR GNPTAB PARVG HIPK3 KLF6 FAM122A MCL1 AGO4 SCP2 AOC3 GAA STK17B CEBPA MYO15B SELP ARHGAP9 GCA BCLAF1 ADD1 ACTR2 TOPORS PRCP RNF149 CRNKL1 UTRN GIMAP2 TYROBP JUNB DNAJA1 CSTA LPCAT2 TUBGCP3 CST7 PPM1F RELL1 PHF2 MEGF6 KAT2B TSPO ARPC2 HSP90AA1 HSPA8 SCPEP1 SOAT1 METTL7A PSMD9 WDFY3 CSF2RB TMEM30A CX3CR1 NFAM1 SRSF11 IFIT5 XRN2	down	*
GSE20727_CTRL_VS_H2O2_TREATED_DC_DN	0.0012502	0.0081211	0.4550599	-0.2785599	-1.468752	173	SIDT2 LPIN2 FIG4 MEF2A MANBA CD1C CNST ATP2B1 CLCF1 SLC2A14 ZDHHC2 CYB561A3 ABHD6 NR4A1 JAM3 SLC25A37 ARHGEF2 KPNA5 STAT5A SYNPO PPM1K FMNL3 ELMSAN1 HCK BTG1 TBC1D5 CDC40 UTRN ETS1 JUNB IFNGR1 STX7 UBAC2 TNFRSF10B RALB CELF2 PLCG2 STXBP3 TFEB GSAP CD1D HNRNPH3 SPOCK2 TNFAIP8 EPB41L5 ACTB SSH2 SIN3A LYST PSIP1 CRYM-AS1 CRBN TGOLN2 CDC42BPB PTGS1 CD79B CCDC93	down	**
GSE12366_GC_VS_NAIVE_BCELL_DN	0.0014644	0.0091466	0.4550599	-0.2764232	-1.468300	177	MYO7B SLC12A6 PECAM1 CD55 HHEX GAPT LYL1 SLC25A30 PLEKHA1 TGFBR2 ABCB1 TXNIP MAN2B1 LAIR1 JAM3 CASP1 TNFSF12 ITM2B ITPK1 RBMS1 SELL PNRC1 DUSP1 N4BP2L1 HES1 HEXB EMP3 APPL1 MAML2 LIMD1 CCDC50 IFNGR1 CD83 GPR183 TSPYL1 SLC25A24 KLF2 YPEL2 CR1 TGFB1 VAV3 GSAP MACF1 CLEC2B PDE4B RXRA INO80D CCR6 ARAP2 MOB3B OPN3 ESYT1 DOCK10 SKI LYST IL16 BMI1 CBX7 SETX CHML NR4A2 RAB37 PATL2 CD69 FXYD5 UBE2W	down	**
GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN	0.0023071	0.0130700	0.4317077	-0.2800231	-1.468062	171	CD300LF SASH1 GLIPR2 SNX10 GPR65 HCAR2 PLEKHF2 LMO2 CCRL2 QKI MSRA MEF2A CASP12 CLCF1 CYP17A1 CHRNE BFAR GPBP1L1 DACH1 KANK2 MTHFR TIMM10B CASP1 MED6 ATF3 MBD2 PIAS1 STK24 HCK SPIN1 BCAR3 STAT4 HMBOX1 STX7 IRF8 GYPC AP3B1 DEDD BLOC1S6 KLF2 RNASEK SPOP CHPT1 BCAS2 SAV1 CCR1 SELPLG EPB41L5 CXCR4 ARHGAP18 RIPK2 TRAF1 KATNA1 FAM13B EHD4 SPATA13 IRF2	down	*
GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP	0.0021628	0.0123674	0.4317077	-0.2812495	-1.467487	168	EPAS1 LPIN2 SWAP70 SPN SNX10 CD44 MYADM IL1RL1 GNPTAB ZEB2 ANXA1 C1orf21 ZDHHC2 SERPINB9 LAIR1 SIRPA IL18R1 MPHOSPH6 BAG1 PTPN12 AHNAK CTSD ITGAX VIM HOPX ID2 DSTN MTPN CD80 GABARAPL2 PHACTR2 RAB8B PLK3 IFNGR1 DAPK2 COBLL1 TBX21 SLC25A24 CALM1 KLRC2 PIK3AP1 SMPDL3B GSAP GABARAPL1 HINT3 NPTN GEM IL18RAP SEC61B ARHGAP18 USH2A SCPEP1 RORA THEMIS2 MIS18BP1 PMAIP1 TSTD3 ENDOD1 CX3CR1 ITGAL ITGB1 MICAL1 HMGN2 BSG	down	*
GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_UP	0.0016030	0.0097261	0.4550599	-0.2764483	-1.467292	178	CXCL3 DLC1 PECAM1 USP12 LRRFIP1 CDH5 TXNL1 CRY2 CHIT1 CIR1 WBP4 SLC11A1 IGSF6 PDE2A GM2A ZNF410 PPP2R2A TFEC TXN MTMR6 HNRNPA3 TNFSF12 TPP1 CD53 ARL4A PPP2R5A TP53BP2 ACTR2 NCOA1 METAP1 MUC3A MAGI2 SH3BP5 VPS26A SP3 PTGER2 UBB CD164 RUNX3 MSMO1 MYL12A NUP153 EHD1 PIK3C3 KCNA3 PPID GTF2B ARAP2 GPX3 PDLIM5 ALDH1B1 CALCOCO2	down	**
GSE3982_DC_VS_NEUTROPHIL_DN	0.0023704	0.0132288	0.4317077	-0.2798236	-1.467242	166	SEMA6A LPIN2 SLC12A6 PDLIM2 LRRFIP1 SH2D3C RHOA NUMB IL18R1 ZEB1 MCL1 MYOZ3 MAP2K3 CFD SRSF5 MEFV STK17B STX3 DENND3 CXCL2 RECK ARAP3 PPP2R5A ANXA3 SNN S1PR4 NECAP1 RHOG JAK1 REL FSTL3 RALB ZNF350 CELF2 ATP6V0D1 ING3 FPR2 NAB1 NFYC ADAM10 PDE4B ETS2 SELPLG RLF CXCR4 TAB2 ARPC5 FOXJ2 PTEN TLK2 ZNF165	down	*
GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_DN	0.0021628	0.0123674	0.4317077	-0.2811694	-1.467069	168	SMAD6 RBP4 CTSW MYADM TBXA2R TGFBR2 SEMA6D RBM7 KLHL30 CNST B3GNT5 GM2A AHRR ABCG1 HERC3 EPB41L2 STAT5A NRARP MPEG1 FBXL3 MGAT4A ST7L NR1D2 RECK PIK3C2A KLRD1 DSTN TBC1D4 TP53BP2 AKIRIN1 ZDHHC20 RPL17 PDK4 RNF149 SGK1 ADAMTSL2 MAP4K4 TMPRSS11D GRASP CGGBP1 EPC2 TSPAN14 PLSCR4 STON1 GRK4 SLC43A2 PDLIM5 THAP6 PARVA JMJD1C PDE4A RORA	down	*
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP	0.0015688	0.0095783	0.4550599	-0.2763239	-1.466451	176	TSPAN4 SLC47A1 PHYHIP CAT ADCY9 LIPA FIG4 CLEC10A MSRA MAL CD1C IL1RN GAS6 RFTN1 ANXA1 MAN2B1 ASAP1 PBOV1 LMNA PLXNA2 RNF125 RNASE1 PEX5L ADIPOR1 EPB41L2 ZMIZ1 IL10 ARRB1 CCL22 AHNAK KLF11 HTT HLA-DQA1 PI4K2A HGSNAT CREM C2CD2 HRH1 CD83 RASSF2 SPRY4 MCUR1 COL15A1 APLP2 PLEKHO2 PLA2G15 RXRA	down	**
GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP	0.0020629	0.0118661	0.4317077	-0.2781728	-1.466299	172	DAB1 CLIC3 OLR1 P2RY1 NUP54 CDH5 TXNL1 CAV1 HMGCR IL1RL1 ABCB1 SH2B3 RRAGC TTL KCNK3 GM2A HDC KIF1C AHNAK SAP30BP PLAUR GRK5 PDE8A CXCL2 PLEKHB2 PPP2R5A PIAS1 GLUD1 ST6GALNAC4 HSPA1B RCAN1 FERMT2 PCGF5 RASSF2 CYP4A22 MOB1A KLF2 MBP DDHD2 VPREB3 GABARAPL1 BRI3 ARPP19 ICAM1 CES3 RTN4 ACADM KIF1B LDLR GSPT1 RNH1 EVI5 CYBA SUGT1 MRPS28 SPSB1	down	*
GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP	0.0027832	0.0149830	0.4317077	-0.2834506	-1.466149	150	PEBP4 EGR2 ARIH2OS AQP9 ACSM1 RCHY1 IER2 CCNL1 GATA3 NR4A1 FAM122A CD93 ZEB1 BTG3 FBXO8 EIF1B PER3 ITPRIP ADO TRIM46 ID3 ZFAND5 STK17B KIF26A CCL4 JAM2 PER1 EVI2A SH2D2A MYH11 CA1 MAFF VAMP3 ARL5B ELP5 PLK3 JUNB GLIPR1 PTGER2 MALT1	down	*
GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP	0.0017515	0.0104046	0.4550599	-0.2790806	-1.465659	164	LPIN2 ZC3H12C THSD1 CLDND1 FYN TGFBR3 ZEB2 SH2B3 ENTPD1 C1orf21 TNIP3 LUZP1 TTYH2 SLC7A11 STOM GATA3 ATP6V1B2 CD58 AHNAK COTL1 MIR24-2 LYAR KLRD1 PPP2R5C SH2D2A CRIM1 PI4K2A PHACTR2 IL2RB SEC14L1 GPR141 RHOJ GPR183 TBX21 CST7 TIGIT GPRIN3 RUNX3 EPHA3 TGFB1 ATXN1 GABARAPL1 SYT11 ARAP2 IL18RAP EPHA4 HAVCR2 TLR10 NABP1 IQGAP1 ARFGAP3 PIEZO1 CDC14A SH3BGRL3 DKK3 ITGB1 ZFYVE1	down	*
KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN	0.0015672	0.0095783	0.4550599	-0.2739525	-1.465194	183	HSD17B11 WDR74 NEDD4L AQP9 SRSF7 VAMP2 PLEKHA1 LAMP1 IER2 EIF1 NLK ABCG1 FOXP1 KLF6 PRSS12 GATA3 RGCC ADRB2 ZYG11B RHOB ARRB1 KLF4 NR1D2 SELL PNRC1 CCND2 PER1 DUSP1 SMAD7 IL7R RBM39 CTSS SOCS3 JUN NOTCH1 KCTD12 GSTO1 CCR7 DDX5 CD7 RALB SLC3A2 FOS FOSB NR2C1 SBF2 PIM1 RGS2 JUND SESN1 SETD4 TDRP TRAF1 TMX2 RNF38 SKI MCOLN2	down	**
GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0023383	0.0131395	0.4317077	-0.2830843	-1.465156	149	SIDT2 FAM167A SIK1 INSIG1 OTUD1 PRKAR1A SWT1 MAP3K8 RNF125 KLF6 CD93 KLF4 FAM76A KLF11 SPAG9 UBQLN1 NR1D2 PRF1 SH2D2A DEGS1 RASGEF1B RYBP OASL PLK3 REL TCP1 TNFRSF9 DENND4A SLC3A2 FOS ATP6V0D1 CCR4 TGIF1 KCTD10 CTNNAL1 LRRC32 TAGAP CRY1 MAGOH NT5C2 ZBTB25 BOK OSER1	down	*
GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN	0.0041528	0.0208584	0.4070179	-0.2813759	-1.465123	147	EPAS1 LPIN2 FYN CYB5R3 IL1RL1 GNPTAB FGR DNASE1L3 ZEB2 LRRFIP2 SEMA6D TACC1 ENTPD1 FOXP1 SPRY2 IL10 SORBS1 CASP1 GRK5 TMBIM1 ITGAX PEAK1 CRIM1 NDNF RAPGEF1 PTGER4 PODXL DAPK2 FRYL PHOSPHO2 ZCCHC9 TIGIT NKG7 XYLT1 PIK3AP1 SMPDL3B LRRC32 PLSCR4 CLDND2 MRGPRF IL18RAP MS4A4A ZBTB25 KLRK1 FNIP2 THEMIS2 SPATA13 KAT5 CD70 CX3CR1 CD109 ATP6AP1L PLXDC2	down	*
GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN	0.0031275	0.0164727	0.4317077	0.3267900	1.464777	170	CEP89 PARPBP CENPF KIF18B NDC80 CHODL TTK CDCA2 RACGAP1 ASPM CEP70 CDCA8 TPX2 GUCA1B KIF23 AP4M1 CLHC1 SAE1 KIF2C POC1A HELB GPSM2 PFN2 ACSF2 SLC18B1 IDH2 MNAT1 DYRK2 NUSAP1 CDK1 NCAPG SAPCD2 PLCG1 ANKRD55 CENPP LGR5 VBP1 IFI27L2 ELMOD3 PKP3 ARF5	up	*
GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN	0.0031725	0.0166378	0.4317077	0.3265691	1.463787	170	CEP72 HJURP FANCI ELOVL6 DEPTOR COIL GAL3ST1 GTSE1 NIPSNAP1 ESPL1 SOX9 SPINT2 CA12 C19orf57 B4GALT4 DLG1 FOXA1 CUL9 EMC9 SMAGP HOMER3 DPY19L1 IFI44L TPCN1 ABCC5 AP1M2 MGLL SLC25A10 MB ASF1B BCAS4 FAM114A1 IGSF3 PIGG ZNF768 KRT19 EPB41L4B GALNT7 GTF3C1 USP18 AHCYL1 RPA1 MYO5C CD2BP2 MMP24 CREB3L2 MARCKS ANK3 UNC119B CAP2 SYBU PCSK5 RAD51 FBN2	up	*
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP	0.0029796	0.0158588	0.4317077	-0.2793466	-1.463760	165	SEMA3G SIK1 CRY2 PLEKHA1 INPP5A YPEL5 RPL23AP53 TMX4 TXNIP ANXA1 UBL3 STOM JAM3 RGCC MOAP1 DAB2 KLF7 ZBTB43 DUSP1 ARL4A TBC1D4 TBC1D5 SAR1A SGK1 JUN PLK3 THUMPD1 IDS PDZD2 GFPT2 CDK14 FOS SFTPC CBFA2T3 IRS2 ZNF136 FCGRT PHF11 TOB1 N4BP2L2 RLF IQSEC1 CEBPD CXCR4 USPL1 EPHA4 NLRP3 PTCH1 SLC2A9 OSER1 TIMP3 P2RX1 DAZAP2 NR3C2 C1orf115 PPP1CB SLC16A10 NR4A2 FPR1 TUBA1A CD69 DNAJB1 SETD2 FCHSD2 NKTR MATN1 SECISBP2 ARGLU1 ZNF331	down	*
GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP	0.0013788	0.0087694	0.4550599	-0.2775056	-1.463193	173	LPIN2 PPARG IL1B GIMAP8 CTSW CALCRL AQP9 CDC42EP2 MEF2A EPB41L3 ACER3 AVPI1 SPIRE1 FOXP1 AKT3 EVI2B TBC1D9 SRSF5 UBQLN1 UBE2E2 PTPRC RAP1GDS1 GNAQ PTGIS CRIM1 HCK PROCR RPL17 C1QA HPGDS RAPGEF1 CCR7 CD83 UNC13B CD7 LETM2 ICAM2 MAPK8 PIK3AP1 GIMAP1 TGIF1 YTHDF2 CD86 HNRNPH3 TAGAP MEIS1 KYNU CCR6 SFT2D1 B3GALNT1 CCR9 SCPEP1 TMCC3 FAM13B CREG1	down	**
GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN	0.0046325	0.0228398	0.4070179	-0.2793573	-1.462933	157	SLC12A6 DENND5A CD55 CD44 TXNL1 SOX17 TBC1D7 ARL8B TRIB1 LYRM4 TRA2B ITGA5 MS4A14 NFE2L2 TCF7L2 CASP5 MYO1B SPAG9 RIT1 CDKN1A ITGAX CCDC59 RSL24D1 TP53BP2 ETF1 CREM HRH1 RAPGEF1 FSD1L ATP13A3 SUCNR1 DENND4A CDK17 SLC22A1 RUNX3 EHD1 TSPYL6 SERPINB1 TSC22D1 CTNNAL1 IFNAR1 PIM1 HSPA2 CYTH1 SAMSN1 IAH1 SLC16A10 UBAP1 SPSB1 MB21D2 HES4 SH3GLB1 PNLDC1 FPR1 EYA3 MT1E LAMP3 GPR137B TRIM13 BBIP1 PLA2G5 DERL2 HIVEP1 SYDE2	down	*
GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP	0.0034890	0.0179875	0.4317077	-0.2774993	-1.460509	169	CD300LF CD52 ASGR1 KLF13 HHEX IZUMO1 P2RY13 ANXA1 CHMP1B RASGRP4 ITPK1-AS1 HLX SLAIN2 SPI1 UBE2D3 EVI2B SRSF5 HNRNPA3 LINC00877 C4orf33 KCNMB1 RNF139 RSL24D1 CD300LB LIN7A VCPKMT SERTAD2 PRKRA RWDD1 PSMA1 GMFG MALT1 DOCK8 FXYD6 TGFB1 ENPP6 TAGAP GABARAPL1 ZNF296 SMAD2 JUND TPT1 TBC1D1 MEGF9 HNRNPK SSH2 P2RX1 LYZ HERPUD1 SVIL CENPC CMPK1 KBTBD11 PLN ANKHD1 ACTR1A	down	*
GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP	0.0013348	0.0085566	0.4550599	-0.2764731	-1.460439	174	HVCN1 GLIPR2 SPN GPR65 EGR2 CTSW MYD88 S1PR1 TGFBR2 RFTN1 LACTB ASAP1 GM2A NR4A1 PPP1R13B CRTAM PTGIR FOXO1 ST3GAL2 FMNL3 NFKB1 COTL1 SELL ID2 CCND2 PRF1 SMAD7 N4BP2L1 STK24 ARL6IP5 S1PR4 IL2RB INPP5B OASL CD48 NXPE3 CCR7 PTGER2 CD7 COL23A1 CST7 GPRIN3 KLF2 RUNX3 NKG7	down	**
GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN	0.0012489	0.0081211	0.4550599	-0.2774058	-1.460209	170	FCN1 SPN CTSW BACH1 MARCO GIMAP6 HEG1 CD5 CHMP1B GNGT2 FOXP1 ADRB1 SLC25A37 APOC1 PTGIR PPM1K PLEKHM3 ROCK1 NFKB1 PTPRC PTGER3 PRICKLE2 CA1 CD300LB HCK SLC25A33 ARHGAP17 CYB5R1 NXPE3 RAPGEF1 UBAC2 CREB1 CD7 TBX21 MBP ICAM2 PPTC7 NKG7 VPREB3 GPR18 ATAD2B CALHM2 SPIB PIP4K2A CD3G PDE8B P2RX1 CREG1 GIMAP4 FCRL1 PSIP1 EBF1 OTUB2 CD79B DNAJC8 VSTM4 S1PR5 STX16 OMA1 RAB39A ABCA3 TNFRSF13C IRF4 NIPAL3 PPP1R14A CD4 MEPCE KLRC1 SLC18A2 PLXNC1 FLT3 RASGRP3 DPP4	down	**
GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN	0.0025708	0.0141523	0.4317077	-0.2784475	-1.459801	171	CXCL3 CLEC3B RCOR1 KIAA1109 MYADM FXYD2 LAMP1 METTL23 ADAM17 NAAA REV3L SLAIN2 RAB14 PSTK BIRC2 RNFT1 FAM76A TMBIM1 PER2 MARVELD1 PNRC1 RECK EPS15 SPRYD7 BCLAF1 FAM76B NCKAP1L MYLIP DCP1A DDX20 STAT4 ATP11A EPC1 STX5 ENTPD4 CGGBP1 TINF2 USP7 TRAPPC10 STXBP3 TMEM230 MIA3 ATAD2B RNF2 GEM ARRB2 DCTN4 SLC25A20 VPS4B TOB2 HNRNPK ING2 TMX2 ACADM TMEM87A EID1 ETFDH YTHDC1 NAF1 HCFC1R1 ATF2 PDCD2 PLEKHA2 MT1E XPO7	down	*
GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP	0.0016743	0.0100831	0.4550599	-0.2747643	-1.459732	179	EPAS1 NLRC4 SLC12A6 PECAM1 HHEX LYL1 CCDC88A CD9 TGFBR2 NFATC3 TMX4 ZBTB4 FBXO7 PCYOX1 ECHDC1 IFI30 GRN EPB41L2 RHOB ZCCHC24 GAA TPP1 KLF7 ATP6V0D2 TLR4 CD302 FRMD4A ARHGDIB NCKAP1L DDHD1 RNF141 SEC14L1 KCTD12 GLUD1 SNX2 GMFG CLN3 ATP6V0D1 KLF2 ALDH3B1 TIMP2 DOK2 FCGRT STK40 BMP2K ESYT1 SLC2A9 CCDC92 B3GNT2 SLC35A1 CBX7 ATP6V0A1 PHYH CRTAP	down	*
GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN	0.0014897	0.0092695	0.4550599	-0.2745195	-1.459540	180	EREG ACP5 OLR1 HHEX LTA4H THBD ENG LYL1 FYN LPL ST3GAL6 BAIAP2 SLC11A1 TGFBR2 GGA2 ADA SLC7A7 LMNA LAIR1 TMEM41B ARHGEF2 SETD3 AHNAK FOXO1 HNRNPA3 ZCCHC24 CDK9 PDE3B DNTTIP2 PPP2R5C SERTAD2 KANK1 PDHX BCAR3 GAS2L1 DNASE2 GSTO1 GRB2	down	**
GSE17721_0.5H_VS_12H_CPG_BMDC_DN	0.0013348	0.0085566	0.4550599	-0.2763027	-1.459539	174	ACP5 DENND5A C18orf32 ENG HSD17B11 BAIAP2 SLC11A1 ANXA1 ADAM17 SERINC1 ZNF503 ZBTB21 PPP2R2A RBM4 SLC25A37 CLK1 ZEB1 IL10 STAT5A MEFV CASP1 SLC7A8 ZADH2 TJP1 LY96 PAPSS1 GCA SACM1L USP25 RPS6KA2 SYNPO2 GABARAPL2 INPP5B CPEB4 DNAJA1 ENPP4 GLIPR1 LYRM1 PRKCE CREB1 RHOQ PSMD12 CCR4 CHPT1 TCF4	down	**
GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP	0.0014561	0.0091066	0.4550599	-0.2767778	-1.459355	173	PRX OSBPL1A GLIPR2 CPEB2 EGR2 PLEKHF2 CTSW MYD88 GGA2 DNAJC3 LMNA SERINC1 IFI30 FAM122A RGCC GRN TFRC GMEB1 IL10 HAUS2 UBQLN1 CAPZA2 N4BP1 C6orf201 IL24 ANXA3 SIAH1 ZDHHC20 RAB6A RBPJ PHACTR2 AQP3 SKIL GRASP KRTCAP2 RUNX3 TIMP2 TSPAN14 RELL1 CCL20 GEM LDLRAD4 YAF2 CDC16 MGAT2 TMEM184B TMEM109 GLUL FAM126B PUM1 RABGEF1 ATP6V0A1 JDP2 FJX1 ATP11B	down	**
GSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_DN	0.0025971	0.0142813	0.4317077	-0.2783464	-1.459272	171	LPIN2 THBD FYN BACH1 BAIAP2 CITED2 MEF2A FBXO3 ATP2B1 MAN2B1 MALAT1 C1orf21 RNF144B ABCG1 ADIPOR1 PPP3CA EVI2B NOSTRIN UHRF1BP1L MAP1LC3B TPP1 ST7L CDS2 TM6SF1 PEAK1 TM9SF2 MAPRE2 NCOA1 GLB1 ARHGAP17 SNAP23 RGS18 NDNF CD48 NOTCH1 APH1B YPEL2 BAZ2B TEC FCGRT GNA13 GPX3 PDLIM5 MIER1 CGRRF1 RTN4 HIGD1C SSH2	down	*
GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_UP	0.0102088	0.0422935	0.3807304	0.3253272	1.459092	168	MUC13 KIF18B SORD RACGAP1 PCLO FLAD1 PLK1 CDCA8 CUEDC1 DIO2 ALDOC GLB1L2 VILL MELK ICA1 TFR2 GPSM2 PPP1R35 PDZK1IP1 CKAP2L RAB13 FADS2 KNSTRN C12orf75 MEA1 FAHD2A KRT18 PHF12 FAM98C NEIL3 ZKSCAN5 ITGA2B IRF6 DGCR6 G6PC3 DLGAP5 SLC35C2 JOSD2 TRADD AARSD1 USB1 DUSP12 TMEM237 TUBA8 AKAP8L	up	*
GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN	0.0013866	0.0087734	0.4550599	-0.2761630	-1.458801	174	OSBPL11 EGR2 TMOD3 CD22 KIAA0355 DPEP2 RRAGC NAAA MTF1 ITSN2 RAB14 KPNA5 GMEB1 VASP DENND3 NFKB1 MAPRE2 RPL17 BTG1 TBC1D5 SERTAD2 VPS37A PHACTR2 SNAP23 ETV3 CELF1 JAK1 DHX15 MORC3 RPS6KA1 GAS6-AS1 ZNF350 KLF2 HIVEP2 HNRNPD DCK CBFA2T3 C16orf72 UTP3 ZNF267 SPOCK2 MBNL1 HACE1 CCR6 PUS10 TMOD2 UBE2D1 CCDC92 DOCK10 SKI CNOT8 DUT TGOLN2 MSANTD3 PLEKHA2 CTDSPL2 CD69 HMGN2 FXYD5 NMI ATP8A1 SKAP2	down	**
GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP	0.0031640	0.0166109	0.4317077	-0.2787388	-1.458136	158	MIR22HG BMP2 GPC5 FIG4 AQP9 INPP5A BCL2A1 TRIB1 TEX2 LRRFIP2 TNFRSF8 MTF1 EMILIN2 IFI30 PTX3 HLX SLC19A1 TFRC KLF4 RBMS1 P2RY2 CARS2 GNAQ MAFF ANXA3 LIN7A CREM SGK1 TULP2 HK3 CTSZ CD83 HERC2P3 GCNT4 PTP4A1 MARC2 MME KIAA0232 MCUR1 TPMT PIM1	down	*
GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_UP	0.0030192	0.0160234	0.4317077	0.3244721	1.457289	175	HJURP PARPBP NEK2 TSFM CDK4 AURKB ALDH18A1 GAPDH UHRF1 AACS ZWINT GOLPH3L TMEM41A AURKA CENPW BRPF3 SLC37A3 SPC24 FNTB COQ9 ISOC2 MRPL37 HDGF GMNN GOT2 SDR42E1 RNF181 NEIL3 USP42 PSMC4 GOLGA3 TRIM16 CCDC134 GALK2 PSMA5 MFSD2A MLEC SIL1 KDELR3 CDR2 GID8 TMEM147 MRPL51 MED27 CBR1 COPZ1 ALG8 PRMT5 EPCAM ECH1 RDH10 FAM118B ATG2A ADRM1 CDC25B MRPL20 ZC3HAV1L TK2 C4orf46 PCTP NCAPH PRRC1 TOP3A PLK4 NLRP14 NFE2L1 FASTKD3 BAK1 CDC34 TMEM167A MTRR DCLRE1A SEC24C	up	*
GSE17721_CTRL_VS_CPG_24H_BMDC_UP	0.0071091	0.0320698	0.4070179	0.3308318	1.456404	146	KIF1A GRIP1 KIF20A CDH17 EYA2 CENPF CHCHD6 DEPDC1 ANKZF1 IFT122 ACOT8 COX6B2 CLPTM1L EMC9 AP4M1 BPHL ASCC2 LETMD1 HES6 KCNJ2 BTBD2 CTDSP2 LINGO1 EPHA1 CENPH GJB3 L2HGDH GALK2 MAN1B1 ACAD10 FUCA2 ACSL6 DNAJB13 ARHGAP12 KIAA0100 KCNIP3 LIPG CKMT2 CELF4 IL12RB2 ESRRB ADM ICK ABHD10 ELOVL4 BMP8B GNA14 ERBB2 DIP2B CDKAL1 ANKRD46 B3GNT4 IMMP2L F5 KCNJ15 LUC7L3 MAN2C1 KLHL42 CAMK2G	up	*
GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP	0.0101013	0.0419911	0.3807304	0.3251083	1.456344	169	LTF HJURP PARPBP UBE2T KIF18B NDC80 BRCA1 TTK POLE SPP1 STIL MSTO1 ESPL1 TPX2 MIS18A KNTC1 DPY19L1 BPHL AURKA CENPW CDCA5 GCAT LMNB1 PDZK1IP1 CENPO RAD51AP1 SPC24 DSCC1 BRIP1 SNAPC4 LRRC45 KNSTRN ANAPC5 KCNE3 CENPH DIAPH3 CENPP ZKSCAN5 DNAJC7 VBP1 CEP192 KIF22 TK1 CHTF18 CENPQ ESCO2 PKP4 CLTA	up	*
GSE3982_MAST_CELL_VS_BCELL_DN	0.0083891	0.0366563	0.3807304	0.3293299	1.455347	152	TP63 GABRB3 APOLD1 SMPD3 FA2H FCER2 RAB36 GLDC MAGEF1 TOP3B FAM169A BICD1 SFI1 KLHL25 SNCG SMYD2 TRPV6 SGPL1 KLHDC4 LIG1 SARS2 REPIN1 NAA40 TTC9 LAMB4 DIDO1 FBXO41 CMTR1 PDK1 RTP4 CCNE1 GDPD3 GALNS COG7 ADAR LIN37 ETV4 ABCA7 URB1 PRSS16 SKAP1 LRRK1 DUS2 CKAP4 ALOX12P2 ALMS1	up	*
GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP	0.0015939	0.0096896	0.4550599	-0.2739293	-1.455054	177	KMO ARHGAP31 IL1A ZC3H12C IL1B TRPC3 CCRL2 ADAM17 ITGA5 MOB3C NFE2L2 LAMTOR3 ATP6V1H TUBB6 ATP6V1B2 PTPN12 STX3 MYO1B SPAG9 DPH3 CDKN1A ACTR3 PLEKHB2 ADIPOR2 PAFAH1B1 PIK3R5 CRIM1 SERPINB8 PSMA1 DNAJA1 GSTO1 NDUFV2 SNX9 HIVEP2 MSMO1 SAV1 TSC22D1 DUSP5 PIM1 KYNU ZNF267 TNFAIP8 TEX10 HSP90AA1 HSPA8 KLLN CREG1 LINC00884 RNF13 ARFGAP3 TNFRSF10D MED31 GPN2 CTSH KCNE1 OSGIN2 SH3GLB1 ZFYVE1 EYA3	down	**
GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN	0.0041511	0.0208584	0.4070179	-0.2764180	-1.454818	169	ACP5 ST8SIA6 FABP4 ADCY9 LYL1 CALCRL BMPR2 S1PR1 TSHZ1 GGA2 PDE2A ZBTB4 PCYOX1 TMEM74B RB1 EVI2B KIF1C TLE4 CCDC82 RIT1 NCOA1 NINJ1 TBC1D5 AXDND1 CCNY ASNSD1 JUNB EPC1 JAK1 GPR183 RASSF2 CDK14 ATP6V0D1 ICAM2 NAA16 TTBK2 MCUR1 RELL1 MFNG CCR6 IER5 IQSEC1 TEX10 SIK3 FOXJ2 AIM2 RHOT1 MAN1C1 FNBP1 SETX CHIC2 LNPEP HEY1 FPR3 FXYD5 GPR137B FCRLA TES WDR26 RC3H2	down	*
GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN	0.0049233	0.0240344	0.4070179	0.3245557	1.454362	167	KIF20A CENPF NDUFS6 TNFRSF11A NLE1 TOP2A NDUFS2 IFI44L AHCY PFKP MTG1 PPP5C DET1 DRC1 TNFRSF21 SEC61G TMEM51 NOP2 GNPAT C19orf47 TAPBPL LONP1 TRIO ZMAT5 MGMT PDRG1 PARP9 ANKRD31 USP18 STOML2 SIRT4 GBF1 CATSPER2 GMPPA STAMBP EIF3D C1orf109 MYEF2 CREB3L2 ETV6 HLCS TYSND1 AURKAIP1 PGAM1 SYNRG CENPE POLR1A FBXO34 ADARB2 RASGRP1 NELFA ACAD8 HEMK1 CHMP6 VPS26B WDR55 LCMT1 FOXRED2 TOMM40 EMB CCS IMP4 RCC2 AP1B1 HINT2 PLOD3 NCOA5 REEP4 RAVER1 HNRNPA1 PPM1G NDUFA9 GTF3A MRPS7 BCKDHA CWC15 IDH3A NDUFB10 DNAJC16 HTR7 VCAN CARM1 RPL24 GTF3C6 TBC1D13 PACS2	up	*
GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN	0.0015592	0.0095783	0.4550599	-0.2757771	-1.454079	173	NLRC4 KMO SLC12A6 SOWAHC CCRL2 FLVCR2 TMEM138 HPS5 ADAM17 HSPB1 NLK ZNF410 ZNF697 MOB3C IL18R1 NFE2L2 LAMTOR3 CES1 ARHGEF2 BTG3 TUBB6 ATP6V1B2 LCMT2 ACSL3 DAB2 VASP SPAG9 SLC25A3 PSEN1 TRIM55 CRNKL1 SERPINB8 DNAJA1 GAS2L3 SLC3A2 SIGLEC17P MSMO1 BTBD7 SAV1 KYNU ZNF267 PITPNA SLC43A2 WDR1 HSP90AA1 LRP12 HSPA8 LINC00884 TNFRSF10D MED31 GPN2 ATP6V0A1 C1QB FUS ZFYVE1 SLC26A11 YRDC CYP51A1	down	**
GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN	0.0053815	0.0258058	0.4070179	0.3228872	1.453566	183	HELLS SPOCK1 TIMELESS GGCT SCN3A PBK NDC80 TTK GINS1 CDCA8 GPI CDC6 MCM2 DTL CCT2 BUB1 RRM2 KIF11 ORC6 MAD2L1 AHCY PERP BLM SPRY1 CKS1B NCAPG2 CDK1 POLE2 GMNN STEAP1 PSMB5 RTCB RECQL4 QPRT PA2G4 RNASEH2A SNRNP25 COL1A2 FAH ATP9A GINS2 KIF20B P4HA1 ORMDL2 LRRC59 MCM6 PPCDC MCM5 RCC1 SLC1A5 ALG8 PRMT5 PYCR1 MSH2 SCO2 VDAC1	up	*
GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP	0.0085367	0.0370682	0.3807304	0.3248339	1.453547	166	MUC13 CEP72 BUB1B KIF18B DEPDC1 DEPDC1B CDCA2 RACGAP1 IQGAP3 LYPD6B NABP2 TPX2 RAD54B ALDOC MICALL2 TJP3 KIF23 EXOC4 EME1 KIF2C MPO ICA1 RHOBTB3 GPSM2 GAS8 CBY1 FADS2 KNSTRN PHF12 NEIL3 DENND1A G6PC3 JOSD2 TRADD TUBB2A USB1 AKAP8L ESCO2 ITFG2 NAT9 ARHGAP12 TADA3 CENPV ZCCHC17 ASCC1 FAHD1	up	*
GSE12505_WT_VS_E2_2_HET_PDC_UP	0.0071955	0.0323698	0.4070179	-0.2975155	-1.453264	105	FFAR4 CLEC1B TMEM52B KL CDC42EP2 TGFBR3 SLC11A1 KCNAB1 ZBTB4 CYP17A1 CLEC7A PRELP ADRB1 SAP30BP STX3 GSDMA ZBTB43 C16orf54 ARHGDIB RPS6KA2 TSPAN18 FMNL2 EBF2 RHOG ACKR3	down	*
GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN	0.0106473	0.0433364	0.3807304	0.3243871	1.453113	169	PAGR1 PHF14 NIPSNAP1 POLE STIL GPI ORC1 IKBKE HAUS5 DNPH1 NUDT1 PCCB EXOC4 BPHL SMARCAL1 RGL1 MMS22L PYCR2 CHEK1 DNAJC9 AHCY CENPO BRIP1 SLC28A2 TMEM106C CENPH NUDT2 ANKRD54 ACP6 PRPF6 RNF181 ZNF623 SERHL2 DGCR6 EXOC7 DLGAP5 NMRAL1 PSME2 SSRP1 TK1 ANAPC1 ATAD5 CNDP2 CDC7 FAF1 POLR2J SIRT5 POLR2I CCNG1 NDUFV1 RPS26 FRMD8 CHMP2A AURKAIP1 ENTPD7 NMT1 GDPGP1 TMEM256 PTOV1	up	*
GSE42724_NAIVE_VS_B1_BCELL_UP	0.0046084	0.0227546	0.4070179	-0.2772128	-1.452870	159	HSPA12B RAB11FIP1 RAPGEF2 PLEKHF2 CITED2 NR3C1 PPP1R15B HDC GLS PPP2R2A ZEB1 CSRNP1 ITPRIP PPM1K CASP1 BST1 SLC7A8 DRAM1 VASP VRK2 IRAK2 FRMD4A UBASH3B KPNA3 MARK3 TFAP2E UBQLN3 INPP5B ELP5 HSPA1B PLK3 JUNB REL GTDC1 ZNRF3 CGGBP1 NAA16 TCF4 IFNAR1 PDE4B ATAD2B PAMR1 SEC63 SETDB2 ATP9B PTCH1 FNBP4 CEPT1	down	*
GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN	0.0026011	0.0142868	0.4317077	-0.2755174	-1.452302	172	EREG RAMP3 IL1A GLIPR2 CPEB2 CD44 HMGCR SLC15A3 VAPA IL1RN TRIB1 APOD PTPRM HBEGF MAP3K8 LITAF HDC KLF6 SLC7A11 SRGN TUBB6 PTPN12 IL10 STAT5A ZFAND5 CLIC4 CDKN1A SELP ID2 CCL4 MAFF MEDAG TDRD7 HCK SLC25A25 EBAG9 ST6GALNAC4 ELP5 FERMT2 TNFRSF9 CD164 RUNX3 EPPK1 TREX1 RIN2 EHD1 FPR2 TBRG1 SOD2	down	*
GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP	0.0103212	0.0425383	0.3807304	0.3425555	1.452301	116	MNX1 MYEOV CPLX2 FAM81A MUC4 EFNA3 NPAS2 INSRR DPYS CETP SLC6A20 MUC6 TMEM132A SMYD2 WIPI2 ANKRD13B MST1R SPAG8 WWC1 BCAS4 TNK2 MAST1 GGT2 KY CNGA4 SPTBN2 LRWD1 FAM207A FBXO44 NR6A1 PROX1 FANCM ADAMTS12 CHRNA3 NEURL4 SH3D21 MAP3K9 TONSL ZBTB32 TSNARE1 LRRC4C BARX2 MORN4 ZNF316 PCGF2 CX3CL1 TMEM72-AS1 LOXL1-AS1	up	*
GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN	0.0029403	0.0157072	0.4317077	-0.2823833	-1.452173	142	GPD1 ACP5 SGK3 ODF3L1 SNX32 IDI1 APIP OTUD4 SPCS3 ANXA1 TRA2B PICALM ADRB2 SRGN ATP6V1H CCNI CSRNP1 FOXO1 ZFAND5 CEP57 RAP1GDS1 BTG1 PKIG YBX1 HCFC2 DESI2 RAPGEF1 IRF8 GMFG PRKCE PIM1 CSDE1 EXOC1 THAP11 TAGLN ARAP2 SESN1 SF1 CXCR4 SSH2 CECR2 FEZ2 DNAJA2 ARHGEF18	down	*
GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_DN	0.0067964	0.0310326	0.4070179	0.3326294	1.452057	134	ATP10B BRINP1 ASB4 GABRB3 CHODL CDCA2 NAALADL2 PLEKHA7 PRC1 HMMR CEL PSENEN KCNV2 EMG1 NEB PLA2R1 PSRC1 POLN KNSTRN OSMR CDK1 KCNE3 STEAP1 NEK5 EFCAB1 NMNAT2 VIL1 MAT1A CLDN12 CDC20 FTCD SIRT4 ZNF558 CKAP2 NMNAT1 FBXO36 PIGX RNASET2 APOBEC2 IL7 MMP16 NAV1 ZNF292 CTTN TBC1D32 SHISA2 DPP10 GLIPR1L1 EIF2D KCNJ15	up	*
GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP	0.0019495	0.0113882	0.4550599	-0.2714358	-1.451734	183	ACP5 LPIN2 IL1A DENND5A FGD5 HCAR2 CCDC88A CAV1 ZCCHC2 STX11 BCL2A1 IL1RN AGPAT4 IGSF6 AVPI1 HBEGF ITGA5 MAP3K8 SLC7A11 CLN5 TUBB6 SLC7A2 PTPN12 CLIC4 CDKN1A ID2 PNRC1 PLEK PIK3R5 SPRYD7 KPNA3 RASGEF1B PROCR RBPJ SYNPO2 ESD STAT4 HSPA1B RCAN1 IFRD1 CD83 GPR183 MALT1 RC3H1	down	*
GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN	0.0024774	0.0137311	0.4317077	-0.2739635	-1.451326	175	USP12 NUP54 FOSL1 TMEM138 STX11 OTUD4 IL23A CLCF1 TRA2B LMNA PPP1R15B BTG2 MAP3K8 CAMTA1 SERPINB9 PPP2R2A RBM4 RGCC NDEL1 ARHGEF2 TFRC SDCBP TAF9 MIR17HG CRIM1 ETF1 RYBP PLEKHA3 RAB8B ARL5B DNLZ RHOG PABPC4 CD83 KBTBD8 TCP1 CEBPZ SLC3A2 FOS RRN3 PSMD12 PPTC7 NIPA2 SLIRP ADPGK KANSL2 ZNF267 PHLPP2 AMD1 ICAM1 ITPRIPL2 TRAF1 KPNA4 TMX2 MAFK	down	*
GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN	0.0019116	0.0111939	0.4550599	-0.2734120	-1.450997	176	CXCL3 CCM2L SLC39A8 CDC42EP2 BCL2A1 FAM49A RFTN1 ASAP1 SLC7A7 BEST1 HECW2 TNIP3 PTX3 HLX SLC7A11 ZNF697 LAIR1 SLC25A37 BTG3 CASP5 PLAUR DENND3 SOCS2 P2RY2 CXCL2 CCL4 FCER1G ALOX5AP N4BP1 HCK IL6 MAML2 PLEKHA3 ETV3 HRH1 MN1 TREM1 ELOVL7 FERMT2 ACKR3 PI4K2B FSD1L ATP13A3 CXCL5 TNFRSF9 ACSL1 PIK3AP1 AZIN1 FPR2 SOD2 KYNU CCL20 ICAM1 MIR155HG IER5 MT1M TRAF1 PLGRKT MAP3K4 MCOLN2 SAMSN1 MT2A	down	*
GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP	0.0015680	0.0095783	0.4550599	-0.2746810	-1.450972	174	SLPI SOX18 CXCL16 LHCGR THBD FOLR1 SUSD2 PAFAH1B2 TBXA2R PEAR1 ABCB1 EDEM1 MTF1 ABCG1 GRN SRGN BTG3 IL10 CASP1 ROCK1 CEBPA SCAF4 CDS2 AXL TLR4 ANXA3 MYO1C KIF13A HUNK CD83 N4BP3 PTGER2 CST7 SNX9 RBKS EHD2 PPTC7 TIMP2 JMJD6 FEM1B CD81 PLEKHO2 HAUS3 LDLRAD4 RIPK2 ITGAE TRAF1 TNFSF9 MMD SPSB1 ENDOD1 SLC38A2 HEY1 DNAJB1 SCAF11 ESCO1 ARHGEF12 FANCC NFIL3	down	**
GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP	0.0044057	0.0219028	0.4070179	-0.2756734	-1.450900	169	OLR1 TMEM52B FGD5 C18orf32 EGR2 SH2D3C LINC00622 NCF2 GALNT18 LRRFIP2 KCNAB1 SLC44A2 HBEGF DNAJC5B GM2A SLC7A11 ZFYVE16 BTG3 TUBB6 ITPRIP PPT1 ADO PLAUR PRKD3 PLBD1 ATF3 ATP6V0D2 ARAP3 PLEK HTRA4 PLCD1 PKIG ARL6IP5 SLC8A1 HCAR3 BCAR3 CCR7 CD83 LGALS2 CDK14 SIGLEC17P RHOQ	down	*
GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN	0.0026526	0.0145206	0.4317077	-0.2751462	-1.450345	172	SOSTDC1 CD101 DLC1 LTA4H SLC16A4 INSIG1 LY86 FCER1A MYD88 BMPR2 SLC39A8 S1PR1 BCL2A1 NFATC3 CD8A IER2 ANXA1 HSPE1 HBEGF EIF4E ATP6V1H CD58 SELL IGFBP2 XCL2 SMAD7 MATK GNAQ TP53BP2 CALM2 RBM39 HESX1 WASF2 JUN TMPRSS11D RPL9 GPR183 PTGER2 ACSL1 UBB PTP4A1	down	*
GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN	0.0018325	0.0108218	0.4550599	-0.2728356	-1.449485	179	SOWAHC WDR74 FLVCR2 MYD88 FXYD2 IL1RL1 VAPA ABCB1 IER2 TXNIP COQ7 LITAF ZEB1 TIPARP FLI1 STAT5A TRIM46 ZFAND5 TMBIM1 FMNL3 P2RY2 UBE2B N4BP1 HCK HESX1 GLUD1 RAC2 JUNB ATP11A PTGER4 PIK3R1 IRF8 PTGER2 SNX1 CAP1 TNFRSF9 SMIM20 RASSF2 LGALS2 MOB1A AZI2 HIVEP2 YTHDF2 EWSR1 IST1 BNIP3L GLTP RNF138 CEBPD TIAM1 OSER1 LDLR FAM13B MT2A SPSB1 CNR2 ZYX ZFP36 ATP1B1 EBF1 UBE2W	down	*
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN	0.0030472	0.0161034	0.4317077	-0.2763747	-1.448935	171	SASH1 LMO2 BACH1 AQP9 FAM49A LILRB3 IL23A TNFRSF8 ADA SLC7A7 C1orf21 TNIP3 KLF6 PTX3 HLX SLC25A37 CD93 TFRC CASP5 IL10 SAP30BP ATL3 P2RY2 CXCL2 IL7R HES1 TP53BP2 IL24 KANK1 HCAR3 FLT1 IL6 SOCS3 CD48 ETV3 STAT4 MAP4K4 WTAP ENPP4 PNPLA8 SIGLEC15 SERPINB6 FSD1L GTDC1 GFPT2 SLC22A1 CALM1 RIN2 PIK3AP1 SERPINB1 FPR2 PIM1 ANKLE2 TNFAIP8 MIR155HG IER5 RND1 PLGRKT PTEN SAMSN1 TRIM36 PAPSS2 CSF2 SLC16A10	down	*
GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP	0.0022051	0.0125949	0.4317077	-0.2758388	-1.448634	164	SLC12A6 TSPAN4 EMP2 GREM2 LIPA FIG4 ALAS1 FBXO3 ACSM1 EPB41L3 TGFBR2 PILRA PDCL RHOA RRAGC PCYOX1 ABCG1 RBM4 NFE2L2 PDGFA PER3 CCDC82 MEFV TSPAN12 FAM76A RRM2B USP2 PER2 NR1D2 CD302 SMAD7	down	*
GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP	0.0095239	0.0402783	0.3807304	0.3272555	1.448314	154	HS3ST1 MAGEF1 P4HTM SFI1 IRF3 CXCR5 AKAP1 SLC9A3R1 BACE2 RABEP2 HPS4 ZNF45 ZNF419 CPNE1 METTL3 UCKL1 ZGPAT PUS1 TRADD ZNF133 ADAM28 LLGL2 PIGG PPOX MYBBP1A MLEC ITFG2 SGSM3 NRF1 NUP85 ABCA7 LPCAT4 ZSWIM8 CD2BP2 IGHA1 LRCH4 HMCES ABCD4 PRKD2 MICAL3 RER1 ZNF224 SEC13 ERBB2 TAF4 NOMO1 BTN2A1 PIAS4 HEMK1 TMCO6 MED22 NSUN5 SBF1 APBA3 RPS6KB2 GAK SAFB2 CXXC1 TSPAN3 SEC24C RGS3 CHKB PAN2 SUGP2 PDXDC1 TLE1 LIN7B	up	*
GSE11924_TH1_VS_TH17_CD4_TCELL_UP	0.0088416	0.0380196	0.3807304	0.3290791	1.447669	142	FAM83F GPR87 HABP2 GRIA4 PDCD2L SAYSD1 SLC4A3 B4GALNT1 NWD1 XDH NOP9 COPG2 CEL LPIN3 SALL2 MORC2 HEBP2 ZYG11A IGSF21 PARD3 DCLK1 DNER OSMR CENPJ RALGPS1 KCTD1 MAD2L2 CHCHD3 CRLF1 C3orf80 CCL21 CCDC151 C9orf152 FHL2 MAGOHB METTL2B NHSL1 MYEF2 LRRC46 CNTN2 PMS1 DCPS AMDHD2 DTNB LRG1 E4F1 EPSTI1 FRZB ERRFI1 KIF24 ZFPM1 ERCC3 SLFNL1 ADRA2B	up	*
GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0017396	0.0103481	0.4550599	-0.2744827	-1.447254	173	ST8SIA6 HVCN1 HSD17B11 MYADM AKAP7 ATP2B1 SBDS ZDHHC2 HSPB1 ADAMTSL4 FLI1 IL10 MTMR6 SORBS1 ITM2B RRM2B NR1D2 SELL HOPX ARHGAP9 RNF139 PIK3C2A PPP2R5A CRIM1 EFR3A ZDHHC20 EMP3 SLC25A33 S1PR4 HECA RAB31 OSBPL9 MSRB3 CDK2AP2 RIN2 GIMAP1 OSGIN1 TEC ICAM1 SELPLG BNIP3L SESN1 IL18 SLC35D2 ZNF143 MMD C2orf42 GIMAP4 RNH1 HERPUD1 CLIP1 ENDOD1 CD79B IRF1 ITGA6 CCPG1 PLLP NIPAL3 AKAP13 TTC39B RNF19B MYO1F CRLF3 SLAMF7 CAPG SLAMF1 PLCL1	down	*
GSE10325_MYELOID_VS_LUPUS_MYELOID_UP	0.0072587	0.0326239	0.4070179	0.3314040	1.446707	134	BRINP1 CUZD1 CYP2J2 JPH3 NPAS2 ABCA12 B4GALNT1 CYP4F11 CETP NLE1 TMEM177 FLG RAD54L RNFT2 NEK11 DCTPP1 CAD C22orf46 SPAG8 REPIN1 PTGDR2 KLHL3 KRT18 GABRB2 SPAG6 ARTN RAB6B ABCA4 IMPG2 FAM86C1 MC1R TPO JMJD4 MLEC CADM3 UBE2O SIRT4 NRXN2 LIPG ACOT11 CYP2D6 CDCP1 WDR4 TUBA4B HLCS	up	*
GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP	0.0029101	0.0155631	0.4317077	-0.2744172	-1.446503	172	TNR PNPLA6 LMO2 CYB5R3 CLEC10A IL1RN RCHY1 TXNIP ATP2B1 RANBP9 PICALM ABCG1 ANPEP SPRY2 HNRNPU MAPK8IP1 FLI1 ADO ID3 SLC7A8 ABCC4 SMAD7 DEGS1 PRCP RBPJ PPP2CA BCAR3 SEC14L1 DHH CYCS DDX5 CST7 NDST1 PPM1F CD151 PTP4A1 XYLT1 HNRNPA2B1 KIAA0232 CD1D ATXN1 DOK2 CCR1 STX12 PHF2 MBNL1 TBC1D1 CTSC TIMP3 GNMT PAK2 GSPT1 INTS10 KLC1	down	*
GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP	0.0113753	0.0458779	0.3807304	0.3228647	1.446294	169	FOXM1 DNAJC22 MND1 PBK PHF14 PLEKHH1 DEPDC1B GINS1 CDCA2 UBE2Z STIL CDCA8 CXCL10 MELK TNFRSF11A SYTL2 AURKA PYCR2 CKAP2L SLITRK6 CLDN9 PON2 CDKN2C CMAS HDGF CENPH ARPC1A SPAG5 SAPCD2 DENND1A DAP TAPBP DBN1 GBP6 SRGAP1 FZR1 PKP4 AHNAK2 PSMD2 BEND6 MYPOP PTHLH SNX11 MYH7B NUP62 RER1 C19orf33 DBNL PAK4 CCDC181 MLLT1 NDUFA8 SYNE2 MSRB1 SMARCB1 FBXL18 CDHR4 ITGB5 TRAFD1 TCFL5 CYP3A7 CMPK2 MTHFD2 CYSLTR2 NUP214 SEMA4D LAG3 EEF1D MED10 LIN9 DNAJC2 ATF5 CCDC18 WDR33	up	*
GSE36009_WT_VS_NLRP10_KO_DC_DN	0.0016840	0.0101211	0.4550599	-0.2718775	-1.446147	187	SWAP70 SOWAHC GPR65 C5AR1 BCL2A1 GIMAP6 AVPI1 CD33 ADAM17 ZBTB21 CLN5 MED26 ARHGEF2 SPI1 RHOB ACSL3 CDK9 MAFG KLF7 TMBIM1 NFKB1 PIK3R5 SMNDC1 CD300LB SIAH1 METAP1 SEC14L1 HECA NECAP1 SERPINB8 ETV3 MTMR14 FOXN2 SKIL YPEL2 SRSF6 TRAPPC10 IRF5 METTL14 TESK2 TSC22D1 IFNAR1 STK40 RNF2 RBL2 IER5 MEX3C RASSF8 ZDHHC5 MCOLN2 DLST SLC16A10 HERPUD1 JDP2 NAF1 RBMXL1 LHFPL2 FHOD1 EYA3 KMT2E PIK3CG SURF6	down	*
GSE45365_NK_CELL_VS_BCELL_UP	0.0013607	0.0086998	0.4550599	-0.2716278	-1.445572	184	CXCL3 THBD BACH1 FOSL1 PAFAH1B2 SLCO2A1 CBL IER2 EDEM1 PPP1R15B SDE2 PICALM NDEL1 ATP6V1H CSRNP1 ID3 VASP THBS1 CDK9 SOCS5 ATF3 SELP ARC DUSP1 SLC25A32 MOB3A IL6 ARL5B JUNB DNAJA1 IFRD1 CD83 FAM43A YWHAZ TMEM128 AGFG1 FOS FOSB BAZ2B FEM1B ATP6V1A IFNAR1 STX12 RGS2 GEM ICAM1 RNF138 ABL2 WDR1 IER5 HSP90AA1 RND1 BCAT1 ZDHHC5 DOCK10 PAK2 EPB41L4A B3GNT2 LDLR NABP1 HNRNPH1 JDP2 EGR1 RBMXL1 SERPINE1 CHIC2 DUSP6 OSGIN2 S100A8 ZFP36 SPTY2D1 BCL10 WWTR1 SLC23A2 ATF6 SH3BP2	down	**
GSE3982_MAC_VS_NKCELL_UP	0.0020345	0.0117443	0.4317077	-0.2721260	-1.445475	177	RAB11FIP1 HMOX1 STAC SLC47A1 FABP4 LYL1 BAG4 PCOLCE2 C5AR1 MSRA LAMP1 EPB41L3 TRIB1 NUMB HBEGF ABCG2 ANXA5 RGCC TNS1 ATP6V1H EPB41L2 CYBRD1 KIF1C FABP5 CCL22 SDCBP PLAUR PAQR5 RMDN3 ERP44 CDKN1A M6PR NRBF2 CMTM6 CLN8 RBPJ APPL1 KCTD12 CD83 ZNF804A	down	*
GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN	0.0123908	0.0489604	0.3807304	0.3258166	1.445127	155	SLC9A3 PKHD1 HNF1A HABP2 HJURP KBTBD12 DROSHA TTC39A PLEKHH1 IP6K3 B4GALNT1 H19 AACS ASTN2 MAGEF1 TPR NUDT17 NRG4 CXCL11 CROCC STK32A ATP2A1 TRIM2 SYN3 PMEL LCA5 C3orf67 ANKRD45 VBP1 ST14 CEP192 OR10AD1 C9orf152 ADAR ENTPD3 C1orf56 LANCL2 AKAP6 CFH COG5 POLR3B TMC2 HLCS VIPR2 EYA4 ERBB2 ALDH3A1 ZSCAN29 TCF3 BCAN SIAE TAX1BP1 COX17 HSD11B2	up	*
GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN	0.0016717	0.0100798	0.4550599	-0.2735616	-1.445059	174	OLR1 SOWAHC CPEB2 CLEC3B GPR65 LPL CD44 LY86 PRKAR1A ITGA5 ANXA5 CST3 IL10 MSR1 MAP2K3 BST1 ZFAND5 CLIC4 DUSP1 CD300C IL7R MTPN YBX1 SENP3 ATP11A APBB2 RCAN1 PTGER4 SKIL CGGBP1 CDK14 RHOQ PELI1 PSMD12 EHD1 TMEM230 IRS2 KCNA3 RGS2 BMP2K RNF138 RTN4 CDKN1C CYB5R4 CUL3 RNF38 LYST FGFR1 GSPT1 SPATA13 PPP1CB EGR1 C1QB FJX1 CTSH ZBTB16 CAPZB CLEC4E SSB ZFP36 NOG EFNB2	down	*
GSE360_L_MAJOR_VS_T_GONDII_MAC_DN	0.0116542	0.0467747	0.3807304	0.3220585	1.444432	168	RUVBL1 CCNB1 IGF2BP3 PSPH SLC2A1 TSPYL5 NDUFS6 FLAD1 MCM2 TYMS EIF3B NDUFB8 DNPH1 MUC6 CHAF1A MCM7 TRRAP POLR3C INPP4B FADS2 IDH2 ALG3 OAT CPNE1 TRAPPC12 SF3B3 OVOL3 ARHGEF16 IGHM SH2B1 HMGA1 CLASRP MCM6 TFAP4 HMCES LSM4 SF3A2 PATZ1 PMS1 MSH2 NFRKB FLRT1 ICK DLEC1 MEP1B ACP1 CIAPIN1 TARBP2 TCF3 PAICS APEX1 PIAS4 CLASP1 GRIN1 ZNF629 F5 RCN2 RNF126 DRG1 SRM PLK4 HRAS RUSC1 MRPL12 APRT IMP4 MSH6 ARFIP2 SHMT1	up	*
GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN	0.0016182	0.0098057	0.4550599	-0.2743714	-1.444237	170	OLR1 SOWAHC LTA4H SMIM12 LPL STXBP6 ALAS1 MANBA LAMP1 IGSF6 TEX2 EDEM1 SLC36A4 SGMS2 TACC1 NAAA CLEC7A HDC SLAIN2 RGCC TFEC PDE4D TMEM38B SLC7A2 PTPRO MEFV BNIP2 NOSTRIN PLBD1 KCTD20 RAP1GDS1 FAM76B RPS6KA2 ZNF330 NEK7 ATP11A PSTPIP2 CREB1 RALB AGPS CPA3 MTMR2 CSDE1 LGALS3 CRY1 COMMD9 WDR1 SEC63 SEMA4A TIAM1 TXNDC11	down	**
GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP	0.0098181	0.0411902	0.3807304	0.3302045	1.442748	137	MNX1 SAA2 PCSK6 GRIK2 FOXM1 HS3ST1 PPP1R1B SLC29A4 GALNT6 ADRA2A CBY3 APOLD1 SLC2A1 TTK SPP1 CD164L2 GRIN2A ASPHD2 AOC1 MAP7 MKI67 RND2 SERPINA3 SPATA17 IGSF21 MARK1 TTBK1 FAM81B DGAT2 SAPCD2 MGMT CPE EDARADD FHL2 MARCKSL1 ANKRD31 CXCL1 PLEK2	up	*
GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP	0.0054323	0.0259849	0.4070179	0.3205815	1.442579	179	PRLR SPATA24 TROAP UBE2T STOX1 DDIT4 NOL12 GPI ORC1 MCM8 LIG3 RUVBL2 EXOC4 CCT5 POLD2 ICA1 C7orf50 PHB SLC25A10 THOP1 PLOD2 IQCB1 GNB1L FOCAD IFT52 EFTUD2 SPEF1 TUBG1 MTOR MLF2 PSME2 SPTSSA C12orf73 NIF3L1 KDELR3 DUS1L CKAP2 TDP1 SNRPD1 EIF3D SUOX NEDD8 SUV39H2 GLO1 PRPF31 CAPN10 MRPL9 TCF25 WDR76 SNUPN ARHGEF39 SIGMAR1 C4orf46 ZBP1 COX17 TRAPPC6A EIF2D MRPS16 HRAS DSN1 EXOSC10 TOMM40 PGAM5 ARFIP2 HDAC3 CMPK2 PC EVA1B PSMD3 SLC44A1 ZNF235 DHRS7 SDHC RAD51B DDB1 INTS4 CUEDC2 FBXO2 RRP1B	up	*
GSE14308_TH2_VS_INDUCED_TREG_UP	0.0023589	0.0131798	0.4317077	-0.2716477	-1.441812	178	SLC12A6 PDLIM2 SECISBP2L DDX6 AKAP7 SPATA1 GALNT18 WBP4 NCEH1 EIF5 PBX3 KLF10 CAV2 SPRY2 SPNS3 PPP6R3 LEPROTL1 TPP1 IRAK2 ARAP3 CLK4 CCSER2 INHBA MYH11 TAF13 MTPN GZF1 BCAR3 NEK7 MAGI2 C20orf194 MAP4K4 JAK1 STX7 ATXN1L DDX5 IDS RBM22 PXK PANK2 SNX9 GPRIN3 ECI2 FOXO3 NAB1 PIK3C3 IRS2	down	*
GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_UP	0.0122491	0.0484792	0.3807304	0.3272687	1.441658	147	BRINP1 FBXW8 TIMELESS CPSF6 TBRG4 DEPDC1B GALNT4 GMPS UHRF1 CAND1 SHMT2 NME1 TTLL12 BRI3BP C7orf50 AHCY KCNJ2 PES1 DTD1 SNAPC1 NOP2 PA2G4 CCNE1 AARSD1 COPS7B COX10 CDC7 CPSF4 L3MBTL2 TMEM106B GPATCH4 CENPT UTP20 ROMO1 HAUS4 GOSR2 TCERG1 PRMT5 BANF1 PDAP1 ACP1 WDR76 POLR1A DDX52 PRPF3 SIGMAR1 DTD2 ESM1 WDR5 NDRG1 SHMT1 IFITM1 RBM8A GTF2F1 NCOA5 LRPPRC	up	*
GSE22886_NAIVE_BCELL_VS_MONOCYTE_UP	0.0099677	0.0416132	0.3807304	0.3262133	1.441575	152	CEP72 TIMELESS SCN3A TTC39A GINS1 LRRC37A3 TSPYL5 CDCA8 TFDP2 HAUS5 SMAGP AUNIP GTPBP3 IGLV1-44 HYDIN WDR78 CD24 KLHL35 BACE2 DDR1 NAA40 C2CD3 DLG5 DBNDD1 MCTP2 NEIL3 PEG10 TRAF5 SEMA4F FGFR1OP ITPR3 SCLY CHST3 FBXO4 IGHM AGBL2 CENPM AP3M2 TIAM2 TBC1D30 SKAP1 MYEF2 ZKSCAN7 NOS1 SLC12A2 TRIB2 PGPEP1 CHL1 RHPN1-AS1	up	*
GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP	0.0069784	0.0316392	0.4070179	-0.2830322	-1.441240	136	ENDOU CPEB2 DPYSL2 YPEL5 DYRK1A ANAPC15 PDE2A KCNAB1 RAPGEF4 NAAA RASGRP4 GM2A IL18R1 KIF1C FOXO1 PSTK KLF11 DAB2 MVB12B BCHE PLBD1 SNIP1 ITGAX LBH HES1 ADD1 EMP3 RPS6KA2	down	*
GSE17721_LPS_VS_POLYIC_8H_BMDC_DN	0.0048641	0.0237933	0.4070179	-0.2737716	-1.440890	169	SLC6A4 CYP27A1 LYL1 INPP5K SAMHD1 MKNK1 FGR SLC44A2 AHRR IFI30 PARVG ABHD6 TFEC TIPARP FBXL3 PMM1 LRRC40 HNRNPUL2 VIM TLR4 PNRC1 PIK3C2A GCA PIAS1 STK24 SLC25A3 STAT4 HIC1 EPC1 HOMER1 TSSK6 RBKS FOXO3 ATG3 WNT11 NAP1L5 ITGA9 SERPINB1 DOK2 BRI3 TOB1 THAP11 PHF2 DBNDD2 IL18RAP SERTAD1 PALD1 GLUL ACADM MCOLN2 CYTH1 IQGAP1 RNH1 SMAD4 REEP1 GREM1 TRMT1L S100A8 MICAL1 SLC9A3R2 DAPP1 HMGB1	down	*
GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP	0.0032191	0.0167933	0.4317077	-0.2733300	-1.440772	172	OLR1 SOWAHC LTA4H FIG4 ZBTB34 TMEM170B LPL RTN3 ALAS1 MANBA LAMP1 SYNC TMX4 DNAJC3 SLC36A4 SGMS2 CLEC7A LAIR1 SLAIN2 RGCC TMEM38B SLC7A2 SNED1 ANKRD10 DAB2 FAM49B KCTD20 GCA EFR3A TAF13 RNF149 KIF13A NECAP1 ATP11A PSTPIP2 MSANTD2 MOB1A AGPS DGKG TMX3 PDS5B CSDE1 ACAP2 ESYT1 TXNDC11 ISCU TTC32 OSER1 AIM2 NRG1 EHD4 RNF13 PAPSS2 CSF2 REEP1 PHYH CD70 TMEM50A	down	*
GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP	0.0032314	0.0168377	0.4317077	-0.2745769	-1.440702	161	RBP4 AJAP1 EPAS1 CXCL3 ARHGEF15 INPP5A STX11 MARCO NR3C1 CD9 PDE4C CD5 SERPINB9 NR4A1 SLC5A2 SYNPO DUSP3 C14orf132 ADO GCHFR ID3 CCL3 CXCL2 RAP1GDS1 GNAQ OXSR1 HES1 PLCD1 GNRH1 NINJ1 LRRTM2 SH3BP5 BMP3 GSTO1 MALT1 TNFRSF10B PTP4A1 PSMD12 RUNX3 TGFB1 CD6 DUSP5	down	*
GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN	0.0045840	0.0226734	0.4070179	-0.2791040	-1.439449	144	ARHGAP31 USP12 TMEM170B HMCN2 TMOD3 SAMHD1 KIAA1109 MYD88 ALAS1 SCARF1 COX18 C1orf162 ATP10A CASP1 TDRD7 FAM102B USP25 FMNL2 ELF1 CREM NSMAF OASL CYCS PCGF5 OSM MORC3 ACSL1 PELI1 AZI2 PIK3AP1 SMPDL3B SAV1 GSAP KAT2B MOB3B INO80 XKR8 ALDH1B1 CCR9 PSME4 SNAP29 TLK2 AIM2 EHD4 FEZ2 MIER3 IRF2 AFTPH	down	*
GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN	0.0073623	0.0329377	0.4070179	0.3207051	1.439272	172	CEP72 CDC45 CHEK2 BRCA1 CDK4 CENPA CDC6 TPX2 UMPS SRPK1 NCAPD2 MRPS35 AP1G2 SPDL1 LDHB NUDT1 C9orf116 PAFAH1B3 CCDC77 SAE1 MPHOSPH9 KIF11 C7orf50 DCTPP1 BRIP1 IDH2 ALDOA C12orf75 ASF1B RFWD3 NEIL3 ANAPC7 DAP POLR2H AGL GPR68 TACC3 AARSD1 CASP7 GAS2 C15orf41 PTER PFAS AAAS RPUSD1 RCC1 HAUS4 LHPP STK35 TCERG1	up	*
GSE7509_UNSTIM_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP	0.0094746	0.0401394	0.3807304	0.3203347	1.439045	171	ZDHHC4 RACGAP1 ALDH1L1 AURKB GAPDH XPO5 RANBP1 CXCL10 PCCB COPG1 NDUFS2 MCM7 RHOBTB3 MRPL3 MCM3 CHAF1B LIG1 PERP CAD MRPS30 PPP5C HSPBP1 DDX56 PPIL1 THOP1 CMAS CCT3 POLR1C SF3B3 NOP2 KPNB1 GIPC1 MOV10 TAPBP SLC26A2 GSS NMRAL1 ATP9A COG7 PRMT7 ENC1 AAMP KDELR3 RPA1 NOL6 MCM6 DHX8 MVP NCDN PLSCR2 SHCBP1 NME4 R3HDM4 ECHS1 NME7 FAM118B MAP1LC3A TBL3 MRPL20 ATG4B TRPC4AP MSANTD4 APEH MED16 ITGB5 ADSL NUDT22	up	*
GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0036093	0.0184909	0.4317077	-0.2757661	-1.438876	168	SIRPB1 C18orf32 MIR22HG TXNL1 RTN3 PRPF38A WBP4 SCARF1 SPCS3 SPG21 SLC36A4 MALAT1 CRK DIABLO GMEB1 AGO3 COQ10B GRK5 AKIRIN1 HEXB MOB4 COPS2 ZFP91 RABGAP1 VPS26A TMEM251 HSPA13 SMU1 MORC3 UVRAG DYM TPRA1 CD164 EMC7 PPP2CB ADPRM AKIRIN2 TESK2 KHDRBS1 CEP170 SETDB2 RAB5A TRAF1 C17orf49 WDFY3 RNF13 RAB2A ATP11B CCNK NDFIP1 TBC1D23 COX20 DNAJB1 LAMTOR5 CCDC93 GABPB1 ANKHD1 CRIPT UFSP2 DERL2 CAPN7 TPST2 FBXL13 ST3GAL1 EIF4A3 HSPA5 RASA2 DNAJB6 MAPK6 EMC2 PRNP APPBP2 GPS2 NUDT21 GID4	down	*
GSE27786_LIN_NEG_VS_MONO_MAC_DN	0.0051188	0.0247409	0.4070179	-0.2732497	-1.438143	169	CXCL3 MRPS18C ADPRH USP12 SLC6A12 MYADM CITED2 NR3C1 WBP4 SPATA21 ERG SLC44A2 PPP1R15B MAP3K8 KLF10 MED11 RIT1 PTPRC AXL TM6SF1 RAP1GDS1 N4BP1 PAFAH1B1 SLC35G6 FMNL2 ASNSD1 CTSS ATXN1L OGFRL1 YWHAZ CYP4A22 RNF146 SLC25A24 ATP6V0D1 NIPAL4 ATG3 MSMO1 PPP2CB EHD1 SPOCK2 PDLIM5 ITPRIPL2 SFT2D1 SLC25A20 AIM2 DAZAP2 BANK1 TRIM36 MED31 CNR2 CLIP1 GPR153 HAS2 ADAMTSL3 FAM160B1 WDR47	down	*
GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_UP	0.0040926	0.0206626	0.4070179	0.3199859	1.437141	175	RUVBL1 TSFM PRIM2 METTL1 BAMBI YEATS4 NNT MCM4 PRC1 RANBP1 C19orf48 KIF23 KNTC1 EEF1E1 RSRC1 RAD54L ANKRD13B MCM3 SEC61A1 EMG1 LIG1 TOPBP1 CHEK1 ORC6 CAD FNTB GLE1 MBOAT1 HSPBP1 PAK1 ATIC KIF2A RNF150 DIAPH3 MYO19 YDJC CENPQ KIF20B PRMT7 TSEN54 MAGOHB ATAD5 CDR2 MCM5 HEATR1 PIGX MSH2 PRPF31 TPGS2 NDUFA8 OSGEP RPN1 TCF3 ALOX15 UBTF MRPL20 NPEPL1 RRS1 WDR55 UTP18 DFFB HINT1 TOMM40 COL5A1 TIMM10 GLRX5 EMB GCSH TIPIN TTC13 IGF1R TBC1D2B NUP37 CTPS1	up	*
GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP	0.0023323	0.0131211	0.4317077	-0.2694862	-1.437109	182	IL1B LRRFIP1 EGR2 GTF2E2 S1PR1 BCL2A1 HPS5 ATP2B1 LTBP4 HBEGF ADAM17 PAQR3 EIF4E IL18R1 NFE2L2 SRGN MAP2K3 PRKD3 SPAG9 PER2 NFKB1 ATF3 CDS2 CCND2 CALM2 PPP2CA PNO1 CD48 GABPA CYCS RHOG TMEM251 IPO7 GLIPR1 SP3 NOL7 ACSL1 HIVEP2 PEA15 DUSP5 GNAI1 ATP6V1A NAB1 GNG5 CD81 UTP3 ZNF267 GEM ANKLE2 WDR1 CEP170 CDC42EP3 UBE2D1 IPO5 SREBF2 COPS8 PSMD9 FEZ2 EIF4G2 SNRPG	down	*
GSE8515_IL1_VS_IL6_4H_STIM_MAC_DN	0.0115155	0.0462901	0.3807304	0.3272466	1.436991	143	ENTPD2 FOXM1 FAM182B FAT2 CHEK2 UGT8 NOVA1 TFF3 C4orf19 SLITRK5 CNNM1 ORC1 CLCN2 GOLPH3L NLE1 SOX30 FOXA1 ADAMTS13 GCAT FBXL8 GNPDA1 LTB4R BMP5 ZNF480 DDX51 ING4 CTDSP2 EFCAB6 SMO PLCG1 ARTN SNCAIP NRIP2 FBXO4 ROPN1B SIRT4 ANKRD1 NFE2 CLDN16 IGHMBP2 ENGASE ULK4 PRDM10 TMC5 SYBU CCDC9 SLC12A2 TONSL SRCAP MYO15A ZNF205	up	*
GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_DN	0.0015680	0.0095783	0.4550599	-0.2697587	-1.435625	184	ACE GPR65 CLDND1 BDNF TMOD3 ST3GAL6 NEDD4L MYD88 IL1RL1 PFDN1 GNGT2 AHRR MAP3K8 SLC7A11 SERPINB9 ADRB2 IL18R1 CD93 TMEM41B RHOB FABP5 STAT5A KLF7 CDS2 SELP HOPX PRF1 DSTN SH2D2A IL7R RBPJ IL6 SOCS3 IL2RB JUN DDX17 ST6GALNAC4 STX7 ACSL1 SPOP EHD1 NAB1 PIM1 CSDE1 LGALS3 ACYP2 GEM ADORA2A GTF2F2 KIT CCND3 MT2A GIMAP4 GPN2 HERPUD1	down	**
GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN	0.0023455	0.0131395	0.4317077	-0.2701992	-1.435240	177	ACP5 MNDA LPXN CLDND1 SLC15A3 CD1C SLC7A7 IFI30 KLF10 JAM3 GRN TFEC GPM6A CD58 ZMIZ1 FABP5 TBC1D9 AHNAK PXDC1 LY96 ABCC4 COTL1 VIM PAPSS1 CCND2 M6PR PLEK EVI2A TM9SF2 SOCS3 RAB31 CYCS GPR183 COBLL1 IGKV3-20 EHD1 CD1D CBFA2T3 NQO2 THAP11 DECR1 SLC35D2 ELOVL1 SEC61B S100A4 CTSC DOCK10 AIM2 SAMSN1 RORA EHD3 USP48 ACAT1 CD70 CTSH BHLHE41 ING1 ITGB1	down	*
GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN	0.0026457	0.0144990	0.4317077	-0.2703916	-1.435145	178	ACP5 TSPAN4 OSBPL1A FABP4 FBP1 TIE1 LIPA LY86 QKI CLEC10A IDI1 MEF2A FGR GGA2 ASAH1 ENTPD1 GM2A IFI30 LAIR1 HNRNPDL GRN CES1 APOC1 EXOSC9 CFD PTPRO TNFSF12 CEBPA CTSD PDE3B FKBP15 KLRB1 SLCO2B1 VAT1 CTSZ DNASE2 KLHL18 CLN3 CD151 TIMP2 BCAS2 DDHD2 CD86 GALC DOK2 NQO2 DECR1 VPS39 BMP2K IQSEC1 PIP4K2A CDKN1C TBC1D1 IFFO1 SREBF2 ACADM	down	*
GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP	0.0018985	0.0111440	0.4550599	-0.2726140	-1.434987	170	CXCL3 IL1B THBD KBTBD3 SPATA1 IER2 RBM7 ADA BTG2 MAP3K8 ZNF410 ADRB2 FBXO8 FLI1 IL10 CSRNP1 COQ10B CXCL2 CTBS CCL4 JAM2 PNRC1 IGFBP2 DUSP1 UTP23 NCKAP5 MOB4 UBQLN3 SOCS3 ETV3 CELF1 TMPRSS11D OSM MALT1 ZNF597 MEAF6 FOS ATG3 FAM204A ING3 BCAS2 IGLON5 EWSR1 ORM2 PDE4B ALDH1B1 SLC25A20 NLRP3 UBE2D1 LRRC4B TTC19 TNFSF9 AIM2 MT2A ZBTB44 ZNF800 TREM2 ZFP36 MT1E CD69 ESCO1 IRF1 ZNF347 DR1 NFIL3 KLHL9 CFLAR PTGS2 CCNC	down	*
GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN	0.0095712	0.0404433	0.3807304	0.3287717	1.434928	135	KIF1A FBXW8 TRNP1 SEMA4B NOVA1 CHODL TUBB2B ACAD9 CCL8 PLEKHA7 CXCL10 KCNH2 IDO1 TIMD4 FAM216B DNAJC9 MTG1 ALG3 RECQL5 DYRK2 CMAS HDGF ABHD17C RAPGEFL1 SPAG6 KXD1 SAPCD2 TMEM237 SRD5A3 ZSWIM1 PRRG2 SLC52A1 KRT8 ASRGL1 PRMT1 HEATR1 CLUH PRSS16 PRSS53 SPON2 FLRT1 BRMS1 FAM118B VWA1 ENTPD7 UBTF RRS1 GRIP2 C12orf43 TLE2 PGAP3 FCGR2B USP49 ALPK2 ARHGEF26-AS1 SLC35C1 DDX49 SLC12A9 FIBP CCDC124 COQ4 CST6	up	*
GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_DN	0.0020345	0.0117443	0.4317077	-0.2714452	-1.433880	174	TUBD1 GPR65 EGR2 IBA57 CCRL2 PRPF38A BCL2A1 IL23A IER2 STARD4 ATP2B1 BTG2 KLF10 ZNF410 NR4A1 EVI2B ADO ID3 NKIRAS1 EVI2A SH2D2A SLC25A32 GZF1 CREM DNAJC27 CRNKL1 CYCS IFRD1 GPR183 KBTBD8 FAM177A1 NAA30 NAB1 PLEKHO2 CCNH GEM MIR155HG SERTAD1 TXNDC15 IER5 TEX10 NLRP3 TOB2 TNFSF9 ZNF165 SLFN11 PUS3 EGR1 ICOS DCUN1D3 YRDC MUL1 CHAC2 BCL10 ANKHD1	down	*
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN	0.0109846	0.0444862	0.3807304	0.3204134	1.433767	166	GMDS BDH1 CENPF IGF2BP3 ANKZF1 TRIB3 CDC25A ASPHD2 ASTN2 RUVBL2 CLDN1 EXO1 HLTF ZNF146 LMNB1 SLC37A3 THYN1 EHHADH BRIP1 FNTB NOL3 GLE1 MEOX1 DLG5 PPIL1 FGGY C12orf75 GOT2 EZH2 DIAPH3 RECQL4 QPRT RAD51D MTA3 TK1 TCEA1 FUCA2 SND1 CEP128 YARS2 NIF3L1 P4HA1 GEMIN6 DHRS1 NFXL1 IARS2 ASCC1	up	*
GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_UP	0.0093733	0.0398141	0.3807304	0.3206481	1.433140	165	SHISA3 TBRG4 ZNF138 CDK4 FCER2 GPI SPINT2 GPX2 KISS1R XXYLT1 FADS2 CNOT3 ALDOA DYRK2 CKS1B CBX5 CEP97 EEPD1 PACS1 ERC2 INTS7 ALDH7A1 SLC23A3 SLX4 COL11A1 NFXL1 PALB2 STOML2 KIAA0100 HPD UPK1B MGME1 GID8 RABEPK LANCL2 NFE2 PRMT5 SPAG4 NDUFV1 STAB1 ECH1 BLVRB INO80E NME7 SNX8 UBAP2L CASC2 EIF4G1 TRIB2 MTHFD1 TP53 ALOX15 UBE2C TTC9C CISH UBTF ENO1 MRPL48 NUP93 WIZ KCNK6 ACIN1 GSTP1 SFT2D2 EDC4 EMB PMVK PLOD1 AP1B1	up	*
GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP	0.0018985	0.0111440	0.4550599	-0.2722382	-1.433008	170	LPIN2 OLR1 GPR15 GPR65 HCAR2 P2RY13 ADAM17 CSRP1 HDC ANPEP GLS PPP2R2A MOB3C CRTAM TXN BIRC2 ATF3 IRAK2 MBD2 PAFAH1B1 PI4K2A SNN DDHD1 SOCS3 JUNB ENPP4 GTDC1 BLOC1S6 MORF4L1 PIK3AP1 GSAP TEX14 FPR2 TSC22D1 NAB1 UTP3 STX12 RGS2 PDE4B ICAM1 XKR8 TRAF1 TMEM184B MAFK EDN1 TLK2 SPATA5L1 FEZ2 DNAJA2 SPSB1 CHIC2 CLEC4E TRMT1L ZYX ZFP36	down	*
GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP	0.0020604	0.0118658	0.4317077	-0.2712407	-1.432799	174	LIMS2 OLR1 SECISBP2L HSD17B6 TTC7B HEATR5B MTMR10 SYS1 AGPAT4 CASP9 KCNAB1 CD36 HBEGF CHMP1B HSPB1 PDGFA CWC22 DUSP3 UBTD1 HAUS2 ZADH2 ATG7 ATP6V0D2 UXS1 CRIM1 MMP19 FMNL2 TMOD1 GABARAPL2 SLCO2B1 MITF CPEB4 C11orf58 FYTTD1 FBXL16 SELENBP1 SERPINB6 BTBD6 FOXO3 RIN2 ZFAND6 ZFYVE9 C16orf72 DYNC1LI1 MFSD12 PDLIM5 RAB5A BRWD1 RAD9B LTBP3 ZFAND2A NIPSNAP3A ETFDH TMEM184C USP4 FJX1	down	*
GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN	0.0046467	0.0228672	0.4070179	0.3193623	1.432605	173	RUVBL1 GBAP1 NDC80 BET1 FA2H CCNB2 MCM4 SPATS2 TYMS COCH LIME1 NME1 GOLPH3L CISD1 GFPT1 EMC9 PCCB TOP2A PDCD5 KIF11 KDELR2 MAD2L1 ABCB9 IDH2 ERCC2 ISOC2 GMNN NCAPG MCAT MRPL17 PDK1 FEN1 CCDC88C DPP3 SPTSSA CASP7 MLEC CDC20 LRRC59 FAM136A GMPPA IGHA1 NEK4 NT5DC2 MVP CYTH2 SCO2 DCPS SHCBP1 SMC2 GGCX MTHFD1 ZBTB32 GPX7 DNM1L WIPI1 ZBP1 PPP1R14B CD38 APOBEC3B AVEN TFG BAG2 MRPL12	up	*
GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP	0.0025444	0.0140548	0.4317077	-0.2691804	-1.428540	176	ST8SIA6 ADPRH HVCN1 DCSTAMP LMO2 CCDC88A S1PR1 CD22 EDEM1 CD36 PLA2G7 ASAP1 MTF1 CLEC7A ZBTB21 ANPEP TTYH2 SLC7A11 CLN5 ADRB2 PTGIR BST1 KLF4 KLF9 CEBPA ITPK1 PMM1 COTL1 VIM SELL ATP6V0D2 DSTN PROCR FRY BCAR3 DDHD1 CPEB4 CTSZ ATP6V0B SNX9 ATP6V0D1 MIA3 COL15A1 BRI3 PLEKHO2 MFSD12 GLTP ALDH1B1 DCTN4 CDKN1C ALDH2	down	*
GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN	0.0026158	0.0143513	0.4317077	-0.2678157	-1.428200	182	CD44 CTSW ST3GAL6 STX11 BCL2A1 PDE2A ANXA1 B3GNT5 NDUFAF7 ENTPD1 ZDHHC2 LAIR1 IL18R1 TXN PPP3CC MAP2K3 NRARP AHNAK YBX3 PLEKHM3 OSTF1 TMBIM1 VIM HOPX ID2 RECK KLRD1 HGSNAT NEK7 IL2RB STAT4 GLUD1 HIC1 IFNGR1 PTGER4 PTGER2 DYM CST7 GPRIN3 SLC25A24 RRAS GSAP LGALS3 NQO2 DBNDD2 RBL2 IL18RAP CDC42EP3 CYB5R4 ARHGAP18 HIGD1C TRAF1 METTL7A TMEM109 LYST MCOLN2 RORA	down	*
GSE27786_LIN_NEG_VS_NKTCELL_UP	0.0086647	0.0374908	0.3807304	0.3176104	1.427352	176	HP AK4 NUP107 PHGDH CDCA2 DNMT3B DGCR8 AURKB DIO2 TFDP2 CDC25A PRC1 KIAA0895 HMMR QTRT1 KNTC1 AUNIP AURKA NUP155 MRPL3 MRPL27 HEBP2 ABCB6 ORC6 CKAP2L FLNB DHRS13 NCAPG2 TMEM106C HDGF C1orf112 TRAP1 MRPS2 DHX33 POLR1C SMO TTC16 HSPA4L EXOC7 RHBDD3 AGPAT5 CCDC51 ANAPC1 LTBR GEMIN6 ERBB3 PPP1R8 TFCP2L1 LSM7 RHOBTB1 STRBP FARSA	up	*
GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP	0.0025529	0.0140697	0.4317077	-0.2686594	-1.427061	177	DNAH17 ACP5 PDLIM2 USP12 KLF13 LY86 CALCRL BCL2A1 IER2 AVPI1 CD36 RRAGC AKT3 ZYG11B RNFT1 PXDC1 COQ10B MAP1LC3B KLF7 FBXL3 CDS2 DUSP11 RECK PINK1 N4BP2L1 CNRIP1 PROCR S1PR4 SOCS3 HECA RAB31 CTSZ JUNB ARHGEF10 STX5 TMEM167B IP6K1 AZI2 GIMAP1 BAZ2B IFNAR1 SLC35D2 PDLIM5 SEC63 ACAP2 SETD4 ULK2 FNBP4 SNAP29 CYTH1	down	*
GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_UP	0.0107379	0.0436321	0.3807304	0.3176162	1.426832	171	SLC13A3 TTF2 EFNA3 MIS18A LDHB MANSC1 ZNF74 KIF2C E2F2 PRKDC GPSM2 PEX6 LMNB1 FAM162A KDELR2 ACTL6A CAD GNPDA1 IDH2 APLP1 HARS2 TRAPPC12 OARD1 CEP192 CDC23 TUBG1 DNAJA3 HIRA SPTSSA COPS7B PINLYP GINS2 DAP3 LRRC20 NAT9 CCT7 FN3KRP YLPM1 MRPL28 SRPK2 LSM7 ZSCAN32 DOLPP1 LSM4 UNC119B NUP62 AP2S1 ABCF3 EYA4 MRPL9 NDUFA8 DNPEP UNKL FZD3 TP53 PWP1 DNM1L METTL18 MED16 SLC38A10 BAG2 HINT1 MPST ARFIP2 DHX32 SHMT1 MTRR TIPIN PLEKHJ1 KEAP1	up	*
GSE22886_NAIVE_TCELL_VS_NKCELL_DN	0.0036619	0.0186817	0.4317077	-0.2693026	-1.426635	175	RAB11FIP1 PTPRE GFOD1 LDB2 NEDD9 LAMP1 FAM49A RFTN1 HEG1 TACC1 MAP3K8 IL18R1 ZFYVE16 ATP10A GMEB1 ZCCHC24 DAB2 SSH1 PTPRC TM6SF1 SH2D2A HTT CRIM1 PI4K2A ADCY2 NOTCH1 STX7 FRYL UVRAG RNF146 PLCG2 RHOQ UBB CDK17 TCF4 GOLGA8H ATP6V1A CLASP2 PLEKHO2 IST1 HELZ ARAP2 INTS6 IL18RAP CEBPD SLC25A20 ARIH1 MEX3C PSME4 TMEM87A LYST SNAP29 ITCH FAM13B FEZ2 SETX UBR2 AOAH SH3GLB1 ATP1B1 WDR41 UBE2W S1PR5 ARHGEF12 UEVLD DUSP22 CFLAR JARID2 LARP7 IVNS1ABP GSN	down	*
GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN	0.0036619	0.0186817	0.4317077	-0.2692933	-1.426586	175	DENND5A RAPGEF2 FYN TMOD3 GTF2I CDC42EP2 INPP5A RFTN1 GGA2 BZW1 EIF4E LAMTOR3 ZFYVE16 ATP10A PTPN12 EIF1B COQ10B THBS1 TMED5 VRK2 GRK5 SOCS5 SNIP1 DSE SH2D2A PEF1 RSRC2 PROCR TULP2 SERPINB8 MITF MN1 PLK3 DUOX1 GPRC5A ZNF350 CD164 NOP10 NAPG AZIN1 PPP2CB EHD1 JMJD6 PLSCR4 PHF11 KYNU MAGOH PLEKHO2 HAUS3 NBN MGAT2 DNAJB9 ZNF165 DOCK4 MT2A MAN1C1 PPP1CB DKK3 HMGCS1 CENPC MYH10 SLC38A2 DNAJB4 FPR3 ACTR1A RAD21 FNDC3A PDPN BBIP1 JARID2 IRF4 MSC CASP3 EBI3	down	*
GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_DN	0.0048291	0.0236458	0.4070179	-0.2734672	-1.425554	155	TUBD1 ABHD5 SFRP4 IL1B TMOD3 ADRA1D SEMA3B BZW1 DACH1 LAMTOR3 CRTAM ZFYVE16 SDCBP FAM49B PDE8A RIT1 ITGAX CTBS CAPZA2 EXOSC8 PEAK1 N4BP1 PTGIS MAFF ANO2 MOB4 TULP2 DCTN6 RAB8B NDNF PHF10 TREM1 TMPRSS11D STX7 LYRM1 HSPA13 CRYM SPRY4 MYL12A ZFAND6 PEA15 DPM1 TEX30 CEP76 CCNH RPP30 TNFAIP8 CES3 PARM1	down	*
GSE3982_EOSINOPHIL_VS_NKCELL_UP	0.0042492	0.0212767	0.4070179	-0.2722304	-1.425200	162	SWAP70 WFDC1 DDX6 RTN3 INPP5A MSLN BCL2A1 FRAT1 FAM49A ASAH1 ENTPD1 ANPEP PTX3 LHX6 CRK SLC19A1 EPM2AIP1 MCL1 MTHFR ZMIZ1 CFD SDCBP ITM2B THBS1 ERP44 PNRC1 UBE2B SLC6A6 GNAQ RSL24D1 NRBF2 CMTM6 PTH1R SNN RBPJ AREG NSMAF SGK1 PPP6C SEC14L1	down	*
GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN	0.0027451	0.0148437	0.4317077	-0.2679606	-1.424864	185	NLRC4 ACP5 CXCL16 KLF13 GAPT PTP4A2 GIMAP8 ENG SH2D3C CTDSP1 FUCA1 CBL FRAT1 TACC1 IFI30 GRN ARRB1 MPEG1 LAPTM5 COTL1 EVI2A PIK3R5 GNAI2 CALM2 MOB3A STK24 HCK EMP3 ARL6IP5 HECA RAB31 DDX17 RHOG RPS6KA1 CAP1 RASSF2 RUNX3 IRF5 TFEB DOK2 THAP11 PLEKHO2 MR1 SLC43A2 CALHM2 ELOVL1 CXCR4	down	*
GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN	0.0050197	0.0243830	0.4070179	0.3178291	1.424612	170	FOXM1 PDCD6 AGFG2 SEC14L5 CENPA WDR70 CCNF DTX3 VILL TOP3B SMARCD3 AP4M1 VASH2 IRF3 HOXC6 MDK RNFT2 ZNHIT1 KIF3C TMEM63A CAD DBNDD1 TMED3 CBX5 KRT18 E2F1 STEAP3 CPNE1 METTL3 DDT PSMC4 MZT2A POFUT1 TACC3 LMNB2 SLC37A4 RHBDD3 PINLYP LIN37 ANAPC1 KDM3B GNAZ USP21 LSM4 MICAL3 VDAC1 SNRPD2 POLR3B PPFIA3 GRAMD1B PAXIP1 RPRD2 SYNRG SART1 GRIN1 RANGRF TFB1M	up	*
GSE27434_WT_VS_DNMT1_KO_TREG_UP	0.0064590	0.0299696	0.4070179	0.3178328	1.424236	167	CEP89 PROM1 PPFIA4 CDK4 ANKZF1 ZFYVE19 CDT1 NR2C2AP PAFAH1B3 ABCC5 AKAP1 SEC61A1 XRCC1 FASTK ING4 RBCK1 STX18 MRPS12 DAP GOLGA3 DLGAP5 JOSD2 ADAM28 MBD4 YIPF3 LMF1 CLTA SAP30 RAD50 GTF3C1 FAF1 ESRRA EIF3K RBM42 ECH1 SCNM1 CSNK1G2 PRPF31 UQCRC1 NBR1 SH2D1B VIPR2 EYA4 SRP9 ETHE1 PNKP RPP25L PTOV1 BCAT2 ENO1 RAD1 SART3 SLC38A10 ISYNA1 HRAS TMEM259 RBL1 ZNF276 BAK1 TYMP KCNK1 RPS6KB2 SEC24C PSMD3 LYPLA2 SYT17 CDCA7L DCTN3 ANAPC11 PTCD2 DAD1 SDHC SDC3 SLC39A3 CIAO1	up	*
GSE25087_FETAL_VS_ADULT_TREG_DN	0.0078484	0.0348244	0.3807304	-0.2718955	-1.423857	157	SEMA3G LRRC8C RUNDC3B SRSF7 EOGT TXNIP ASAH1 RNF125 FZD4 LITAF ABCG1 FOXP1 MS4A1 DGKE KLF9 MED6 SPAG9 NR1D2 SELP C9orf72 PIK3C2A UBASH3B HTRA4 BACE1 MYLIP VPS37A ZNF548 HECA OXNAD1 OSTM1 IDS TNFRSF10B CELF2 CDC37L1 RPL21 IRS2 KCNA3 TAGAP TOB1 TSPO CCR6 CGRRF1	down	*
GSE15659_RESTING_TREG_VS_NONSUPPRESSIVE_TCELL_UP	0.0101288	0.0420694	0.3807304	0.3260560	1.423361	134	CEACAM1 BBOX1 ENTPD2 CPLX2 ASB4 DEPTOR COIL CBY3 PAGR1 CHRNG BCL2L14 DPYS BBS1 COPG2 C15orf54 EME1 CARD10 CACNA1G ENPP3 CCDC88C ATAD3A FAM86C1 ALX4 DCAKD ARHGEF16 AMPH CTSV SCN8A AAMP CHPF COG1 DUS1L ENTPD3 CDK5RAP2 BLCAP DUS4L AP4B1 EIF3K ATP6AP1 CYTH2 DOHH ARHGAP5	up	*
GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP	0.0044037	0.0219028	0.4070179	-0.2714418	-1.423293	166	SNX10 RAPGEF2 EFCC1 FOSL1 WBP4 TRIB1 EDEM1 DNAJC18 CARD16 ADA PPP1R15B ZNF697 NDEL1 BTG3 CD58 PTPN12 PLAUR ST3GAL2 COQ10B PLEKHM3 CDKN1A IRAK2 PER1 INHBA N4BP1 PEF1 HCK BTG1 TMOD1 PKNOX1 COPS2 PDCD6IP ETV3 PTGER4 LYRM1 OSM RAB8A TNFRSF9 TAGLN2 CALM1 PIK3AP1 LRRC32 ADPGK PITPNA ICAM1 MIER1 TNFAIP8 ELOVL1 B3GALNT1	down	*
GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN	0.0044337	0.0219970	0.4070179	-0.2712118	-1.423045	161	KLF13 GLIPR2 LRRC8C CLDND1 CTSW ST3GAL6 AQP9 ELF2 SFR1 B3GNT5 KLF6 PRSS12 CAV2 CST3 EVI2B PPT1 MAP1LC3B SELL ARAP3 UBE2B EPS15 GNAQ PIK3R5 HEXB AQP3 IFNGR1 UBAC2 GMFG GPRIN3 RUNX3 ICAM2 SPOP PPP2CB METTL14 ZC3H12D PLSCR4 KAT2B SERINC3 NR2E3 FKBP1A TAB2 CTSC LYST CNN2 USP48 SUGT1 CENPC LNPEP MZT1 ICOS SNW1 FXYD5 TES FAM78A AKAP13 RNF19B MYO1F ANKH CRLF3 CPNE3 INF2 DPP4 ZC2HC1A AIDA	down	*
GSE3039_CD4_TCELL_VS_NKT_CELL_UP	0.0026827	0.0146036	0.4317077	-0.2678394	-1.422705	177	GPD1 SLPI PDLIM2 TMEM150B GIMAP8 CCDC88A INPP5K NEDD4L P2RY13 PDE2A SH2B3 PTS PARVG HIPK3 STOM CLK1 ZEB1 RIT1 MARVELD1 UBE2E2 CDS2 LBH PRICKLE2 IKZF5 CDKN2AIP TGFB2 PIAS1 ARHGAP17 CREBRF PHACTR2 PIKFYVE HECA MTMR14 UBAC2 CREB1 FSD2 PDZD2 CGGBP1 CELF2 HNRNPH3 UNC13D ICAM1 ANKLE2 CCR9 TRAF1 SSH2 RBM48 P2RX1 DOCK4 HEBP1 CCND3 IQGAP1	down	*
GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP	0.0049660	0.0241702	0.4070179	-0.2714536	-1.422401	165	RAB11FIP1 SOSTDC1 SNX10 FYN LY86 ZCCHC2 VAMP2 CD1C CBL CD22 GGA2 DPEP2 SLC25A37 PDE4D KPNA5 SYNPO FOXO1 TNFSF12 LAPTM5 ALOX5AP WDR48 GCA TBC1D4 MAPRE2 HGSNAT RPL17 BTG1 TBC1D5 FRY CDC40 RNF141 PIKFYVE CD83 IRF8 KLHL18 MORC3 UVRAG MARC2 VAV3 GSAP ITGA9 TGIF1 TSC22D1 KYNU ETS2 CXCR4 MFAP5 ZBTB25 NLRP3 KATNA1 RET LYST PDE8B	down	*
GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP	0.0026827	0.0146036	0.4317077	-0.2675744	-1.421298	177	KCTD9 FOSL1 PRPF38A ZBTB2 SH2B3 CD5 SBDS LATS2 CHMP1B EIF1 EIF5 BTG3 LRRC57 HNRNPA3 TPP1 PER2 CCL4 SH2D2A FAM76B RABGGTB SNN METAP1 CRNKL1 CNTN3 STAT4 IFRD1 IRF8 CGGBP1 TINF2 SNX9 SLC3A2 PSMD12 CPA3 CHORDC1 SERPINB1 VAMP4 IRS2 RELL1 APLP2 ETS2 RNF138 SLC31A1 NBN MGAT2 RBM18 TRAF1 DNAJB9 PAIP2 GSPT1 CNOT8 SNRPG CENPC CLOCK SLC38A2 ZFP36 WAC MFSD1 UBE2N DDX21 CHKA SH3BP2 TAF1D	down	*
GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP	0.0051139	0.0247409	0.4070179	-0.2710693	-1.421120	171	SIRPB1 ACP5 FCN1 LTA4H CYP27A1 LIPA FIG4 CCRL2 VAMP2 FUCA1 FGR EIF4A1 CD37 DUSP3 ADO PXDC1 FUT7 ITGAX HLA-DQA1 MAPRE2 PI4K2A SIAH1 GLB1 RPS6KA2 PRCP BCAR3 CYB5R1 VAT1 STX7 EEA1 CD83 STX5 SERPINB6 RASSF2 CLN3 PLCG2 CD151 IRF5 PIM1 FCGRT PCCA GSTM5 ALDH1B1 LMOD1 SEC61B IFFO1 TMEM184B KCNJ9 SREBF2 ATF4 SMPD1 ETFDH ATP6V0A1	down	*
GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN	0.0050573	0.0245168	0.4070179	-0.2715847	-1.420712	158	SEMA6A ACE COQ2 TGFBR3 SCARF1 LRRFIP2 KIAA0355 COQ7 CSGALNACT2 HIPK3 IL18R1 SPTBN1 CLK1 BTG3 SORBS3 FOXO1 YBX3 USP2 KLF7 MYO1B ERP44 NPAS3 IGFBP2 ARAP3 SLC25A32 PI4K2A TOPORS DCP1A BCAR3 SH3BP5 AK1 IPO7 PABPC4 CST7 SNRK SLC3A2 CLUHP3 LMCD1 TNFSF13 ICAM2 SORT1 OSGIN1 MEIS3P1	down	*
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN	0.0027348	0.0148209	0.4317077	-0.2673617	-1.420168	177	ABHD5 USP12 ZBTB34 BACH1 SFR1 DYRK1A ZBTB2 TGFBR2 TEX2 TMX4 PCYOX1 LMNA KLF10 CLK1 ZYG11B RHOB FOXO1 ACSL3 SLC12A4 PAPSS1 CPT1A TP53BP2 MAFF AFF1 IKZF5 RSRC2 RASGEF1B FAM102B LIN54 TOPORS MCMBP MYLIP PPP2CA WASF2 RYBP APPL1 JUN MTMR14 CPEB4 IRF8 MBNL2 MSANTD2 OGFRL1 CGGBP1 YPEL2 RUNX3 IRF5 PARD6A RELL1 TAGLN RNF2 ICAM1 TOB2 OSER1 GLUL MARC1 KIT CHCHD7 USP48 ZNF326 SLC16A10 ETFDH SERPINE1 TMEM43	down	*
GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP	0.0027348	0.0148209	0.4317077	-0.2672814	-1.419741	177	CXCL3 EREG MIR22HG TXNL1 KIAA1109 ELF2 SFR1 IL1RN TSHZ1 MAP3K8 HDC MED19 SLC25A37 PPP3CC PTPN12 CASKIN2 CLIC4 UBQLN1 NFKB1 CDKN1A PTPRC PRF1 CCSER2 SNN RPS6KA2 UFM1 APPL1 LRCH1 ETS1 IPO7 ENPP4 OSM TRAK2 RNF24 NDST1 RNF146 CD74 ING3 ZRANB1 TBRG1 HBP1 JUND IER5 TBC1D1 TTC32 ADORA2A MCOLN2 JDP2 CHIC2 ZNF800 ATF2 CLEC4E MAPK1 CLOCK FUS	down	*
GSE7852_LN_VS_FAT_TREG_DN	0.0024751	0.0137311	0.4317077	-0.2686499	-1.419114	174	ARHGAP31 RAPGEF2 INSIG1 IDI1 AGPAT4 NCEH1 SGMS2 PBX3 ZNF503 RNF125 FZD4 RGCC NDEL1 SRGN RHOB DUSP3 AHNAK UHRF1BP1L DRAM1 MAFG GRK5 EPM2A TMBIM1 HOPX ID2 PER1 DUSP1 ADIPOR2 MAFF NINJ1 RBPJ RBP7 ELF1 MITF COBLL1 TPP2 DENND4A YPEL2 PKD2 CCR4 IRF5 TGIF1 GALC RELL1 TOB1 ETS2 IL18RAP ITPRIPL2 ARL14EP MEGF9 MARC1 DNAJB9 TNFSF9 SAMSN1 MT2A IQGAP1	down	*
GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP	0.0053815	0.0258058	0.4070179	0.3165276	1.418778	170	HKDC1 ABCC2 KIF20A EGLN3 TROAP KIF18B SMPD3 RACGAP1 ANLN TFDP2 ARHGAP33 PRC1 TMCC1 MAP2K6 WDR90 KCNG3 PLEKHG1 MELK KIF23 KNTC1 TOP2A YKT6 CD2AP KIF11 CKAP2L GAS8 PTGDR2 TSHR SPRY1 EEPD1 TRIM41 SAPCD2 DIAPH3 GAL3ST4 UBN2 GOLGA3 ANP32E DNMBP RBM33 EFCAB7 CENPV EFHC1 ODF2L UBL7-AS1 KPTN DDX23 SLC35A3 CEP152 RFC5 ACSF3 ELOVL4 ARHGAP11A UHRF1BP1 SRP9 WDR76 CELSR2 TCF3 TRIM62 SYNE2 PPIA DDB2 C4orf46	up	*
GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_UP	0.0025529	0.0140697	0.4317077	-0.2684112	-1.417853	174	SGK3 LPL MYD88 CLEC10A IL1RN FGR ANXA1 ARHGAP10 LTBP4 HBEGF CLEC7A ANPEP TOR1AIP1 TUBB6 SLC5A2 PTPRO PLAUR AIRN SLC7A8 COTL1 ITGAX VIM ID2 CD53 CAPZA2 HTT IL7R HLA-DQA1 MAPRE2 VWF TDRD7 HGSNAT USP25 EMP3 CTSS C2CD2 MITF VAT1 NSMCE2 CD74 RIN2 TIMP2 TGFB1 LGALS3 BRI3 ATAD2B GPX3 FKBP1A CHMP3 TDRP ARPC5 SNAP29 GRB10	down	*
GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN	0.0053490	0.0257005	0.4070179	0.3156109	1.417491	175	RUVBL1 MCM10 RACGAP1 NDUFS6 CDCA8 PTTG1 CDC6 SMPDL3A ORC1 CCNF DTL MAGEF1 LDHB CASP2 HMMR CISD1 KIF15 MRPL15 SAE1 MCM7 KIF11 CAD ETFA IDH2 CMAS RFWD3 C1orf112 SPAG5 CBX1 DNAJC7 CHCHD2 ILF2 ST14 COA3 PSME2 MSRB2 STOML2 RPA1 SRRT MRPS33 UIMC1 HMCES POLR3E NT5DC2 NDUFV1 DCPS DENR ATOX1 NBR1 PFKM SNRNP200 NUBPL TNS3 BCL6 SEPHS1 UBE2C RASGRP1	up	*
GSE2706_2H_VS_8H_R848_STIM_DC_UP	0.0045583	0.0225919	0.4070179	-0.2702417	-1.417000	166	RBP4 ACP5 PECAM1 HVCN1 CCRL2 PRAM1 CDC42EP2 DPEP2 SGMS2 BTG2 AHRR ZNF503 ABCG1 ZNF697 NFE2L2 SPTBN1 SLC19A1 MAP2K3 LINC00528 KIAA0513 ZCCHC24 DENND3 PLBD1 PLEK PINK1 MAFF BACE1 HCAR3 TECR SGK1 CELF1 DUOX1 PTGER2 ADNP2 SIGLEC17P FOXO3 ICAM2 SORT1 TIMP2 TGFB1I1 PHF19 MFSD12 GEM ICAM1 ESYT1 CTSC P2RX1 CBX7 EGR1 CRTAP TREML1 DCUN1D3 TREM2 PLXDC2 PIGK PTGS1 QSOX1 FXYD5 ABHD14A	down	*
GSE3982_EOSINOPHIL_VS_BCELL_UP	0.0054579	0.0260696	0.4070179	-0.2708605	-1.416923	158	MCOLN1 COQ2 INPP5A PDE4C FUCA1 TGFBR2 TRIB1 ANXA1 SERINC1 EPM2AIP1 ADAMTSL4 RHOB FBXL5 ZMIZ1 ARRB1 SDCBP TPSG1 PTAFR KCNMB1 TLR4 CD302 PTGER3 DUSP1 SMAD7 ADIPOR2 SLC6A6 TLL1 HCK SEC14L1 NOTCH1 HK3 BMP3 FOXN2 PPP1R15A DAPK2 PSTPIP2 PTGER2 TNFRSF9 UBB ZNF669 MMP15 DOK2 CRY1 GLTP CHMP3 ACACB G3BP2 PKNOX2 PDE4A PTEN THEMIS2 GRB10 CREG1 CNR2 NR4A2 HIPK1 FUS AOAH ICOS FPR1 EFNB2 ADAMTSL3	down	*
GSE27896_HDAC6_KO_VS_WT_TREG_UP	0.0087258	0.0376972	0.3807304	-0.2705132	-1.416618	157	KCNA2 LRRFIP1 BAIAP2 TSHZ1 KIAA0355 ATP2B1 HECW2 MAP3K8 SPRY2 ARHGEF2 ARRB1 ZADH2 NR1D2 CCL4 PEAK1 NCOA1 ARHGAP17 PKNOX1 UTRN ETV3 LRCH1 GABPA UHRF2 FOXN2 CREB1 HOMER1 SNRK AGFG1 HIVEP2 STRN TGIF1 CNTNAP1 APLP2 KAT2B GEM SFT2D1 NSUN4 MEX3C STK4 PAK2 PUM1 MIER3 SPATA13 MED17 ARHGEF18 ABI1 SETX DUSP6 PRKCH KMT2E ATP1B1 FAR1 XPO7	down	*
GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN	0.0046098	0.0227546	0.4070179	-0.2701677	-1.416612	166	WEE1 CLEC1B SLC31A2 ACP5 RAMP3 ZMYND15 LYVE1 PTPMT1 BAIAP2 SLC39A8 LAMP1 ITGA5 EIF4E LAIR1 MTHFR EFCAB14 MOAP1 EPOR RNFT1 DSE MRVI1 SNX3 CD80 SERPINB8 FAM189A2 AK1 REL EGLN2 CD164 MAPK8 TGIF1 IFNAR1 GALC TMEM107 CLASP2 SLC10A6 IST1 PRDM8 ICAM1 CTTNBP2NL LRP12 PARVA TMCC3 MT2A ENY2 ATF4 CSF2 HERPUD1 NAF1 MB21D2 MYH10 EYA3 MT1E CALR CD69 CYP51A1 UBE2N TRIM13	down	*
GSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN	0.0093621	0.0398141	0.3807304	0.3200061	1.416031	151	GABRB3 HBA2 SEMA4B THOC3 SORD STK36 XPNPEP1 PAH GPX2 KCNN4 RPL39L HOMER3 BPHL SMYD2 GNAS-AS1 GCAT NSUN2 PYCR2 ASS1 NFYA EHHADH GLE1 PLA2R1 APLP1 DDX51 GABRB2 TCF20 RNF181 SLC26A2 YIPF3 FBXO15 TSPO2 DAP3 BCL2L1 FANCM CKMT2 CAPRIN2 LTV1 LRIG1 RTKN NEFH EPCAM GTF3C2 MRPL55 VIPR2 SAMD4B SRP9 TARBP2 FBXO45 COX6B1 SARDH UTP18 ARHGEF25 COL5A1 MAD2L1BP COQ5 GCSH DLGAP4 CYP3A7 PC THAP4 HAL ORC5 RAB3IL1 COPS7A	up	*
GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_DN	0.0111933	0.0452563	0.3807304	0.3166067	1.415077	165	KLHL31 AVIL CDCA7 NNT COPB2 ZWINT CCT2 RRM2 ZNF146 SEC61A1 MCCC2 PSMD4 GNPDA1 MRPL36 MEA1 ING4 POU5F1B TRAPPC12 GOLGA5 ZNF623 DNAJC7 EFTUD2 VBP1 GNPAT SLC26A2 CCT7 TADA3 ORMDL2 MRPL24 STAMBP HAX1 MRPL51 PDIA4 ALG8 PMS1 PRIM1 HDLBP ECH1 MTIF3 SCOC NDUFA8 AURKAIP1 UQCRQ TMEM260 SRCAP IGLV3-19 ENO1 CYB5B APOBEC3B APEH KCNJ15 PAQR8 DRG1 SHQ1 DGUOK TMPO MRPS6 ABCD3 XRCC5 MTF2 SLC44A1 HM13 DDB1 FKBP2 SUCLG1 METTL5 WDR92 NDUFB10 LRIF1 PCNA DPY30	up	*
GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP	0.0036216	0.0185342	0.4317077	-0.2694415	-1.415037	164	EPAS1 DLC1 LTA4H SLC16A4 INSIG1 ARHGEF15 LY86 BMPR2 SLC39A8 RBM14 RPL23AP53 NFATC3 DDO IER2 TMPRSS6 ANXA1 HBEGF MAP3K8 PBX3 ATP6V1H SLC7A8 CLDN5 ATF3 SELL XCL2 MATK SH2D2A TP53BP2 VWF JUN TMPRSS11D GPR183 GPRC5A ACSL1 SLC3A2 CDK17 PKIA TIMP2 TEX30 GNAI1 GRK4 PHLPP2 SMAD2 RAB5A TIAM1 DIXDC1 GPD1L SREBF2 ANXA11 GRB10 GRPEL1 SNRPG STARD13 SERPINE1	down	*
GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0028747	0.0154078	0.4317077	-0.2683613	-1.414978	173	ST8SIA6 ST6GALNAC3 GFOD1 STX11 LACTB PTPRM SLC3A1 GM2A RB1 ADAMTSL4 CYBRD1 STAT5A ARRB1 AHNAK FOXO1 YBX3 KLF9 SOCS5 ITIH5 SSH1 ATL3 SELL NINJ1 MYO1C NSMAF IL2RB NDNF STAT4 CPEB4 PTGER4 EEA1 RTN4R LETM2 TOM1L2 GRSF1 PELI1 NKG7 IRF5 TGIF1 TEC CTIF STON1 SELPLG SESN1 ITGAE TRAF1 TMEM184B BCAT1 KIT RORA NRP2 RNH1 FCRL1 JDP2	down	*
GSE360_L_MAJOR_VS_T_GONDII_MAC_UP	0.0073433	0.0329130	0.4070179	-0.2717284	-1.414888	147	SLC31A2 CSDC2 FCN3 IL1B MMRN1 CD44 CYB5R3 ACSM1 RHOA PLA2G7 FBXO7 ANXA5 LITAF CAMTA1 MS4A1 STOM CRK PPP1R13B ARHGEF2 GPR4 AHNAK KCNMA1 PLAUR ZBTB43 SH2D2A ACTG2 HCK AQP3 STAT4 MTMR9 CCR7 NPR1 WDR7 RRN3	down	*
GSE42724_B1_BCELL_VS_PLASMABLAST_UP	0.0105165	0.0430421	0.3807304	0.3182684	1.414649	160	PRR15 XYLB NOXRED1 GAPDH PRKCA HOXB7 CDC25A NDUFB8 KCNN4 FBF1 SEMA6C TTLL12 DUSP23 ACTL6A SPC24 TXLNB HPS4 IGFBP5 BIRC5 TNK2 SLC16A13 MRPL17 POLR1C ACTR3B PPP1R36 PELP1 UBAC1 GSS LRRC8D GAS2 HIP1R NDUFA13 TTLL10 COX10 EPN1 FN3KRP TTLL3 ACLY TBCA ROMO1 SNAP47 HAUS4 ENGASE NCDN MRPS25 USP39 BMS1 TRIP4 PFKM NOS1 SNX8 AGBL5 MXD3 TIMM44 SF3B2 TMEM98 MRPS26 TMEM161A SPHK2 ITGB5 GSK3A NSL1 MARVELD2 AP2A1 TTC13 TXN2 TPPP ANK1 TAOK2	up	*
GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP	0.0041362	0.0208175	0.4070179	-0.2670314	-1.414604	175	MS4A7 KCNA2 RBMS2 FABP4 ENG ARRDC4 ABCB1 RRAGC MALAT1 CLEC7A ZNF503 STOM TRAF6 SRGN CST3 TIPARP TRIM46 SCAF4 DUSP11 DUSP1 CPT1A MBD2 CMTM6 NCOA1 PIAS1 ARHGAP17 PKIG SGK1 NKD2 UTRN NXF1 MTMR14 JUNB MORC3 TSPYL1 IP6K1 RIN2 BAZ2B VPREB3 SBF2 LGALS3 CCR1 KAT2B RASSF8 JMJD1C ANXA11 TMCC3 ITCH ZFAND2A	down	*
GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN	0.0041362	0.0208175	0.4070179	-0.2669234	-1.414031	175	RAMP3 ST8SIA6 OTUD1 PLEKHF2 SFR1 ADAM17 RAB33B ACOT2 REV3L FOXP1 PAQR3 MS4A1 ADRB2 ZYG11B KLF4 KLF9 ATF3 C9orf72 PNRC1 ELMSAN1 AFF1 IL24 TOPORS RBM39 MYLIP ETF1 SGK1 LRCH1 CCR7 LSM1 STX5 GPRIN3 KLB FOSB FAM204A PIK3AP1 ING3 ZCCHC10 IRS2 C16orf72 PIM1 TAGAP RGS2 GRK4 NRN1 PDE4B PIP4K2A RIPK2 TDRP TRAF1 C7orf31 DNAJB9 BANK1 USP48 FHL5 NR4A2 FUS MYH10 SLC38A2 TUBA1A CALR CTR9 TSC22D2 MEF2D CCNYL1 SLU7 PLA2G4F LRP1 NOL11 RBM4B ST3GAL1 FAM107B	down	*
GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_UP	0.0082822	0.0363193	0.3807304	-0.2695706	-1.412817	159	CXCL3 OTUD7A ZC3H12C SNX10 PTPRE HCAR2 CCRL2 MYADM CALCRL ZCCHC2 PRPF38A IL1RN GINM1 SLC25A17 EIF1 RGCC TMEM123 SPI1 SLC7A2 COQ10B ZFAND5 MAFG KLF7 NFKB1 CXCL2 ATF3 DUSP1 KPNA3 HCK SERTAD2 RNF149 LIMD1 ETS1 JUNB ACSL1 PELI1 HIVEP2 TREX1 EHD1 GSAP	down	*
GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN	0.0083802	0.0366501	0.3807304	-0.2694674	-1.412276	159	SLC31A2 USP12 GPR65 LPL MYD88 FGR LTBP4 WNT2B STOM GNG7 ATP6V1H TBC1D9 PXDC1 PARVB PDE8A PPP2R5A ADD1 SEC31A SIAH1 NINJ1 EMP3 SLC25A3 ESD CYB5R1 STAT4 KCTD12 DDX17 BTD PPP1R15A WTAP CCR7 PABPC4 IDS HERC2P3 CDK2AP2 ZBTB24 CD7 TNFRSF10B	down	*
GSE14415_NATURAL_TREG_VS_TCONV_UP	0.0058838	0.0278308	0.4070179	-0.2759973	-1.411524	139	MRPS18C ZBTB34 CHIT1 VAMP2 YPEL5 IL1RL1 PEAR1 TXNIP B3GNT5 CHMP1B FOXP1 IL18R1 HNRNPDL PDE4D PPP3CC CCNI RAB12 ITIH5 PER1 SMAD7 CPT1A MBD2 UBASH3B FOXN3 MYLIP ARL5B IFNGR1 PTGER2 TIGIT CD164 ZRANB1 PDCD1 ATXN1 GIMAP5 ZBTB25 TBCEL NHLRC3 NFKBIA GPR171 SAMSN1 DAZAP2 CSF2 CCNK GPR55 ARHGEF12 CD3E PPFIBP1 GNPDA2 CD226 JARID2 TTC39B MFHAS1 SETBP1 F2RL2 IL10RA BTBD19 TMEM71	down	*
GSE360_DC_VS_MAC_UP	0.0084782	0.0369408	0.3807304	-0.2693080	-1.411441	159	FOXF1 GREB1 PTPRB LMO2 SAMHD1 ADCYAP1R1 INPP5A PRKAR1A MKNK1 WNT2B RAP1A PAQR3 GLS RBM4 SRGN ITSN2 PDGFA PPT1 HNRNPA3 SMNDC1 SIAH1 GLB1 CCR7 SP3 CD83 MBNL2 ZNF804A ENTPD4 REL CELF2 MOB1A USP7 MYL12A AP1G1 VAMP4 GPX3 CPQ ALDH1B1 ESYT1 TRAF1 STK4 CD1E PSMD9 ARHGEF18 EXPH5 ATP11B TGOLN2 TUBA1A IFIT5 API5 KIDINS220 MAN1A1 FNDC3A	down	*
GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN	0.0055384	0.0263763	0.4070179	-0.2695887	-1.411370	162	KMO RAMP3 LPXN LYVE1 CLEC12A LIPA ARRDC4 OTUD1 RTN3 MANBA C3orf70 NUMB EDEM1 PPP3CA IL18R1 HERC3 HPSE2 FLI1 TLE4 SPNS3 CASP1 PIP5K1B ZCCHC24 VIM TEF N4BP2L1 MATK SH3BP5 TYROBP IFNGR1 FSD2 RPS6KA1 UVRAG CPA3 VAV3 NR2C1 IFNAR1 ACTN2 GRK4	down	*
GSE557_CIITA_KO_VS_I_AB_KO_DC_DN	0.0100160	0.0417434	0.3807304	0.3139100	1.410723	176	RUVBL1 TTF2 SORD B3GAT1 MRPL46 GMPS WDR70 PMS2 PAFAH1B3 SAE1 E2F2 WDR78 MRPL3 PFN2 GET4 IFT172 CENPO TMEM63A HES6 ETFA RAD18 SYMPK C7orf26 PPIL1 KCTD7 ANKRD54 SLC25A13 DYNLL2 SAPCD2 ZNF354A DPP3 SATB2 C19orf47 HIRA SSRP1 HDAC1 LAMTOR2 EPN1 PTER CENPV PPP1R8 FAF1 MED24 TMCO4 KATNB1 TCERG1 NUP62 PFKM DNAJC10 ZMAT2 MRPS27 TTC9C DTD2 TTLL5 TMEM201 TRPC4AP C9orf40 RTN4IP1 CHMP6 FGFBP3 ZNF496 BAG2 GSK3A NELFB PRPF19 ROPN1L TUBGCP2 CS HNRNPAB TMEM181 PSMD3 E2F4 ELMO2 MEN1 METTL9 VPS4A OIP5 ACTN4 WDR12	up	*
GSE27786_BCELL_VS_NKCELL_UP	0.0100160	0.0417434	0.3807304	0.3138736	1.410559	176	PDE11A UNC5CL STRC SPATA24 C1GALT1 TBRG4 KCNQ5 TYMS KCNMB4 SHMT2 SIMC1 CCDC150 BTRC CARD11 CCT5 WDR3 MCM7 CHD6 DNAJC9 TIMM50 ZNF48 MGA CMTR1 LRRC42 SLC2A13 GDAP1L1 ITPR3 C3orf67 SCLY SPG7 ADNP AARSD1 LONP1 STOML1 HDAC1 EDARADD PLEKHB1 COX10 CABLES2 DGKA GID8 SRSF1 POLR3E PDIA4 LSM4 CEP152 CSNK1G2 MLLT6 LPGAT1 CARHSP1 ZSCAN22 ENTPD7 RPP25L ZSCAN20 IMMP2L CLNS1A CNPY4 WDR64 NSUN5 CLPP PPP2R5E FASTKD3 PANK4 RCC2 CNTROB STEAP2 NUDCD1 KIAA1217 MEN1	up	*
GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN	0.0049345	0.0240652	0.4070179	-0.2659329	-1.410159	181	WEE1 FAM167A IL17RB TSPAN4 FGD5 TMEM126A LPXN TRPV2 ENG EGR2 CTSW CCRL2 RTN3 MSRA GNPTAB TLCD2 PFDN1 DNAJC18 RAP1A LITAF RGCC IL18R1 SRGN FABP5 TLE4 YBX3 PXDC1 MAFG UBE2E2 ID2 KLRD1 VAMP5 RABGGTB TDRD7 HGSNAT RNF149 CD160 PSEN1 KCTD12 PLK3 IPO7 TCP1 CST7 SLC3A2 RUNX3 NKG7	down	*
GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP	0.0059096	0.0279076	0.4070179	-0.2693206	-1.409098	153	SWAP70 LYL1 LY86 LMO2 MYADM CD22 CD8A GGA2 IFI30 MS4A1 CLK1 EPB41L2 LRP4 EVI2B PPT1 SRSF5 PLBD1 C11orf91 PLEK HLA-DQA1 PDK4 CD8B MYO1C ADCY2 DNAJC27 HMBOX1 LIMD1 LTBP2 CD83 IRF8 RASSF2 CST7 PLCG2 NKG7 CD74 GIMAP1 IRF5 TCF4 TEC SLC10A6 ZNF296 CCR6 CALHM2 SPIB RIPK2 ITGAE S100A4 CD19 EHD4 FCRL1 CSF2RB CDON CRTAP CTSH TNFSF8	down	*
GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN	0.0037458	0.0190895	0.4317077	-0.2654759	-1.409055	178	CPEB2 PTP4A2 FYN PPP4R1 GFOD1 TGFBR3 NEDD9 EOGT ZEB2 SH2B3 MAP3K8 TTYH2 KLF6 STOM ADRB2 CD58 AGO4 AHNAK CASP1 HOPX PRF1 EPS15 SMAD7 KLRD1 UTRN SH3BP5 TBX21 CST7 TIGIT PLCG2 RUNX3 NKG7 ATXN1 DOK2 PLEKHO2 KAT2B CLEC2B SYT11 MIR155HG CALHM2 TOB2 S100A4 CTSC MCOLN2 ITCH	down	*
GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_DN	0.0094746	0.0401394	0.3807304	0.3127647	1.408255	180	GINS1 NOL12 WDR70 AP1G2 CCT2 RANBP1 QTRT1 MRPL15 YKT6 LARS2 PDCD5 MRPS11 EEFSEC TTYH3 TADA2A ALG3 PES1 CCT3 DHX37 MRPS2 LARP1 FEN1 NUP205 CNOT11 UQCC2 POLR2H TELO2 YDJC MRPL52 UBE3D ADAR GINS2 ITFG2 DNAJC11 NUP85 COX10 YARS2 ZCCHC17 FAF1 RPUSD1 LSM7 RCC1 NEDD8 MVP TTC1 ECHS1 MLLT1 LLGL1 RHOT2 TARBP2 MTHFD1 PRPF3 PPIA CISH CDKAL1 OAS3 ASCL2 MTG2 CYB5B BCKDK DHDDS ZNF619 NSUN5 LCMT1 PGAM5 WDR5 LRP8 XRCC5 FIBP CACNA1A GTPBP4 TMEM183A WDR12 ITPA HMBS TXNRD3 POLE4 IFI35 ZNF823 USP31 TCTEX1D2 CPSF1 NDUFS4 POLR2C PCNA PUS7L PSMD11 SLC7A1 CARM1 ZNF653 GTF3C6 ISY1 RHBDF1	up	*
GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_UP	0.0051372	0.0248054	0.4070179	-0.2698959	-1.408247	168	SLC16A12 F2RL3 SNX10 PID1 TRPV2 LMO2 ECSCR TBXA2R CASP12 SLC11A1 GGA2 ERG EDEM1 PKHD1L1 ADA LAIR1 EIF1B SNED1 CASP1 DRAM1 LY96 CTBS HPSE GNAI2 BACE1 ARHGDIB NCKAP1L CTSS HCST HMBOX1 HK3 CTSZ TYROBP IRF8 SDHD IDNK UVRAG SMIM20 SMPDL3B EPHA3 TGFB1	down	*
GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN	0.0049079	0.0239831	0.4070179	-0.2689301	-1.408077	160	ZC3H12C MIR22HG EGR2 NXPH3 FCER1A KANK3 FOSL1 SLC15A3 TRIB1 IER2 CD33 GM2A TMEM74B TIPARP MAP2K3 FABP5 DUSP3 GAA PLBD1 LBH M6PR PLEK ELMSAN1 WFS1 SH2D2A RASGEF1B RPS6KA2 KCNA5 RBPJ HPGDS SFTPB HIC1 ATP6V0B MALT1 PREX2 RGS13 CST7 ATP6V0D1 HSF5 TGFB1 VPREB3 TAGAP RGS2 MLANA PRDM8 CGRRF1 TOB2 NRP2 TOX2 ANO6 EGR1 CDON DUSP6 NR4A2	down	*
GSE2826_WT_VS_BTK_KO_BCELL_DN	0.0027348	0.0148209	0.4317077	-0.2665241	-1.407885	174	SLC6A4 GPD1 EPAS1 SC5D IL1A HMOX1 TSPAN4 PPARG BDNF LPL AATK CORO1C GINM1 NFIX ABCG2 AHRR GATA3 SOX7 ARRB1 PTPRO ITM2B NES THBS1 SOCS2 RIT1 CADM1 AXL PINK1 MATN2 CA1 PLAC9 SLC8A1 CD160 ADRA1A DAPK2 ACKR3 SERPINB6 TNFRSF9 ACSL1 PEA15 SBF2 ATP6V1A PDLIM1 SLC10A6 DBNDD2 IL18 CPQ NBN TRAF1 S100A4 PALD1	down	*
GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN	0.0065505	0.0302528	0.4070179	-0.2685195	-1.407752	171	ARRDC4 TMEM170B PDE1B AKAP7 MOB1B TEX2 LMNA LATS2 GM2A NMUR1 GATA3 TFRC TUBB6 KDSR ADARB1 LRRC57 SORBS1 NPNT PTAFR ST3GAL2 PXDC1 TPP1 PDE8A IRAK2 PI4K2A CD80 AREG CREM PHTF2 COPS2 KIF13A CNNM2 SNX29 GLUD1 PODXL RPS6KA1 AGPS DDHD2 TEX30 TEC TSC22D1 BMP2K CEP170 RAB5A FBXO30 TMX2 KIT FNIP2 EHD4 TMEM43 HMGCS1 PTGS1 CD69 FANCC SLC43A3 ATP8A1 RAB1A KATNAL1 DUSP22 SRXN1 NFKBIZ ZFP1	down	*
GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_UP	0.0079946	0.0354090	0.3807304	0.3140459	1.407267	167	GMDS FBXW8 MND1 SLC5A1 DGCR8 ACOT8 KAZALD1 LMLN NOP9 DCBLD2 ERAL1 MRPL27 SNHG11 EMG1 NEK11 COMMD4 PPP1R37 BMP5 MRPL37 DGAT2 FEN1 NUP205 NLN ANKRD55 ZNF606 C3orf80 JOSD2 SSRP1 RHBDD3 PKP4 NDUFA13 CNDP2 DHRS1 CDC20 MYPOP SLC38A7 USP21 CUBN PIGX PHC2 SNRPD2 RFC5 PAK4 HAS1 HK2 GOSR1 FBLIM1 MPG FAM185A RASGEF1A RRS1 SCAF1 COX17 FBXL18 RPUSD3 BCKDK TOMM7 LONRF2 UTP18 LAMA5 MARVELD2 TASP1 MTR NETO2 FNTA CS HNRNPAB IL17RC DTX4	up	*
GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP	0.0105574	0.0431507	0.3807304	0.3130977	1.407072	176	HELLS BUB1B NUP107 CCNB1 KIF18B NDC80 RACGAP1 SLC27A2 ASPM ESPL1 TPX2 CCNB2 RBBP8 MCM2 TYMS PRC1 SHMT2 MELK KNTC1 KIF2C KIF11 TOPBP1 BLM MEOX1 NUSAP1 NCAPG PA2G4 RNF44 DLGAP5 TRADD COL9A2 KIF22 TK1 HDAC1 MLEC AGPAT5 HLA-A JTB RAD50 POP7 MCM6 THOC5 PPCDC CREB3L2 PSMB4 STK39 ATAD2 DCPS RFC5 TRIP4 NME7 SMC2 CENPE MTHFD1 IFI16 CD38 APOBEC3B LASP1 AVEN HINT1 TMPO BATF NIT2 SEC24C RMI1 SMAD3 POLD3 SMC4 GTPBP4 XRCC6 P4HA2 COL6A3 RFC3 BARD1 RFC4 CHFR FUT8 GALT FKBP3 OPTN DHFR DDX46 SP110 NUP50 CRELD2 SLC25A12	up	*
GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP	0.0038421	0.0195228	0.4317077	-0.2650966	-1.406867	176	SIK1 ZBTB34 IBA57 PAFAH1B2 ZBTB2 EDEM1 SH2B3 DNAJC3 HBEGF SLC36A4 TACC1 SDE2 CRK LRRC57 ADO KLF11 MAFG ITGAX KCTD20 RNF139 SMAD7 PIK3R5 SNN SERTAD2 BTBD18 PPIL4 GZF1 SAR1A FOXP1-IT1 NXF1 NECAP1 ATXN1L CD83 GRB2 NUDT15 RUNX3 NAPG ABHD13 MAP3K2 PPP3R1 STON1 WBP2 PLA2G15 PITPNA GLTP CCDC69 TMEM184B NEK3 DAZAP2 MAPKAP1 PURB GRPEL1 CFL2 NR4A2 USP30 ANKS1A XPO7 FAM160B1 NFIL3 MEF2D FASTKD5 FCHSD2 METRNL GPATCH2L SLC25A28	down	*
GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP	0.0027402	0.0148335	0.4317077	-0.2672622	-1.406816	170	SNX10 SLC6A12 CDH5 FYN LPL BCL2A1 OTUD4 UBL3 PPP1R15B EIF5 BTG3 SGCA BAG1 PRKD3 CLIC4 RBMS1 ATF3 M6PR CLK4 MBD2 DSTN RAP1GDS1 DEGS1 PLAC9 USO1 EEA1 CD83 THUMPD1 ATP13A3 TCP1 AGFG1 KLF2 CD164 AZI2 DCK TEC RELL1 DOK2 ACADL ACYP2 PLAA MBNL1 GPX3 ARPC2 RTN4 HNRNPK TRAF1 FNBP4 KIT PSMD6 MT2A IQGAP1 DNAJA2	down	*
GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP	0.0031532	0.0165721	0.4317077	-0.2646985	-1.406256	179	IL17RB SWAP70 LTA4H SAMHD1 NEDD4L QKI AKAP7 INPP5A IL1RL1 C3orf70 CBL USP47 ACER3 PTS SLC7A7 ENTPD1 CYB5A SRSF2 TFRC LRRC57 SOCS2 ITIH5 RBMS1 SELL CAPZA2 EXOSC8 PEAK1 UBASH3B TP53BP2 ZDHHC20 SLC25A33 CHDH PHTF2 IL2RB CPEB4 SLC14A1 GSTO1 CD83 TNFRSF9 SNX9 RIN2 KHDRBS1 PIM1 COL15A1 CD81	down	*
GSE27786_LSK_VS_NEUTROPHIL_DN	0.0060957	0.0285560	0.4070179	-0.2687646	-1.406189	153	PTCRA JPH4 AQP9 ZCCHC2 SLC44A2 MALAT1 OLFML2A RAP1A PARVG SLC7A11 RGCC GRN PTPN12 MTMR6 MED11 RRM2B MAP1LC3B LY96 LAPTM5 HOPX RECK CAPZA2 ACTG2 MOB3A CMTM6 TAF13 RBP7 HECA MTMR14 ETS1 MED30 CYP2A6 ZBTB24 TRAK2 GJA4 MBP SERPINB1 IRS2 PPP3R1 THAP11	down	*
GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN	0.0031855	0.0166701	0.4317077	-0.2665712	-1.405539	173	PECAM1 HVCN1 PLEKHF2 CALCRL GTF2I SLC39A8 PLEKHA1 CD22 NFATC3 ABCB1 KIAA0355 UBL3 FOXP1 SERPINB9 C1orf162 EPB41L2 ADARB1 TAPT1 SLC38A11 MYO1B LAPTM5 NFKB1 UBE2E2 HPSE UXS1 ALOX5AP BTG1 PRCP FLT1 SENP3 CCR7 OGFRL1 SNRK BLOC1S6 NIPAL4 ICAM2 HSF5 SAV1 VAV3 CHRAC1 APLP2 BMP2K SELPLG MOB3B SESN1 BLOC1S2 SEMA4A TBC1D1 ZNF471 MMD P2RX1 FCRL1 IRF2	down	*
GSE31082_DN_VS_DP_THYMOCYTE_UP	0.0063764	0.0296712	0.4070179	0.3135484	1.405425	170	NUP107 CHCHD6 GPATCH1 IFT27 GPI LIG3 SRPK1 CCT2 QTRT1 CUL7 MCM7 PDCD5 PKM TXNDC5 MBOAT1 ALG3 MGAT4B SLC25A10 CCDC40 DHRS13 TMEM106C UCK2 GTF2E1 E2F1 SEC61G MECR UQCC2 LONP1 MRPL11 TMEM237 PDRG1 METTL22 LAMTOR2 MAGOHB RAD50 STOML2 CHCHD1 POLR2J MRPS33 ROMO1 TXNL4A LHPP DPH5 MRPL14 NTMT1 CISD3 PDF WDR4 BMS1 HLCS RNF7 EIF4G1 SIGMAR1 FAM185A MRPL48 NUP93 BCKDK RPL23A MRPL12 COMTD1 HINT1 TUBGCP2 IMP4 MRPS6 CS NDUFB2 TIPIN NBAS METTL9 PDSS2 NMD3 KIF16B GRWD1 METTL5 DRG2 YIF1B FKBP3 DPY30 PSMC2 MRPL19 PARK7 GTF3C6 LDHA	up	*
GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0031855	0.0166701	0.4317077	-0.2665426	-1.405389	173	MSRA LILRB3 CD33 TACC1 LCP1 TOR1AIP1 TAPT1 GAA STK17B SELP ARHGAP9 SNORA28 PPP2R5C NRBF2 LMBRD1 TOPORS PRCP S1PR4 SLC8A1 RNF149 SNAP23 OASL GIMAP2 GLUD1 TYROBP JUNB RCAN1 SNX2 HERC1 IDS RC3H1 CST7 ACSL1 TIMP2 CHPT1 RELL1 PHF2 TSPO ARPC2 XKR8 DCTN4 DHRS12 MEGF9 SCPEP1 PLGRKT FAM126B AIM2 C21orf91 CNN2 EVI5 UBR2 RBMXL1 TMEM50A CX3CR1 S100A8 FAM8A1 NFAM1 RNF167 IFIT5 FAM160B1	down	*
GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN	0.0066975	0.0307540	0.4070179	0.3129141	1.405379	175	PPFIA4 TOMM34 MCM2 SPINT2 TYMS ZWINT MUC6 POLD2 MCCC2 AIMP2 DNAJC9 PFKP INPP4B ALG3 UCK2 BIRC5 TRAP1 FEN1 CPNE1 EZH2 FADD TRAF5 POLR2H TELO2 OVOL3 SNRPA RAD9A SLC37A4 CASP7 IL15RA DNAJC11 CCT7 RIN1 GBF1 ARHGAP22 PEX5 TMEM147 TFAP4 AATF POLR2I CH25H RCC1 TCERG1 CDH1 FKBP9 SNRPD2 NME4 UQCRC1 DLEC1 MEP1B ACP1 CPOX TARBP2 TCF3 ADRM1 SCN9A HGS TIMM44 CHERP RCN2 HRAS RUSC1 MRPL12 NIT1 RBL1 SAFB NHP2 TYMP GAK THY1 SHMT1 PC ANK1 MEN1 PDE1A	up	*
GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_6H_UP	0.0065005	0.0301046	0.4070179	-0.2681535	-1.405109	165	SLC24A4 NLRC4 PNPLA6 CCM2L CD55 EMP2 CDC42EP2 C5AR1 YPEL5 FAM49A TRIB1 LILRB3 TNFRSF8 SLC7A7 BEST1 EMILIN2 TNIP3 SERPINB9 SLC25A37 CASP5 LINC00877 PTAFR DENND3 SOCS2 UBE2B FCER1G N4BP1 HES1 RYBP SOCS3 ETV3 RAB31 PNPLA8 FSD1L APH1B PIK3AP1 EHD1 DCAF5 SERPINB1 FPR2 IRS2 SOD2 PLEKHO2 CCDC69 IER5 MEGF9 MAP3K4 SAMSN1 CCND3 LINC00884 TRIM36 SLC16A10 FJX1 S100A8 FPR1 CYB5R2	down	*
GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN	0.0032373	0.0168440	0.4317077	-0.2663492	-1.404369	173	SMAD6 EPAS1 SLC12A6 KLF13 HHEX TRPV2 HSD17B11 CTSW LAMP1 CBL PDE2A GM2A ABCG2 IFI30 CYB561A3 EVI2B ITPRIP PTPRO LEPROTL1 ID3 STK17B SPAG9 PDE3B PTPRC HPSE ELMSAN1 CPT1A AFF1 ADD1 TMEM9B CREBRF WASF2 ETS1 OSBPL9 IFNGR1 AP3B1 CD74 HBP1 ANKRD13A SERINC3 HELZ BMP2K CCR6 CALHM2 CDC42EP3 SPIB CNN2 ARHGEF18 CDKN1B ICOS PLEKHA2 FAM53B RNF167 PIK3CG MICAL1 HLA-DRB1 MAP4K2 RCSD1 FCRLA	down	*
GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP	0.0053313	0.0256410	0.4070179	-0.2663676	-1.404072	172	PRX KANK3 CALCRL INPP5A C8orf58 CASP12 NCF2 PEAR1 ENTPD1 ABCG1 CLN5 ABHD6 DACH1 IL18R1 PPP1R13B KANK2 TFEC HERC3 TUBB6 SORBS3 CCNI CSRNP1 PRDM16 EXOC3L2 PPM1K PDE8A PTPRC TLR4 ALOX5AP ELK3 INSL6 RASGEF1B HEXB APPL1 RGS18 STAT4 SH3BP5 ETS1 BTD ELOVL7 RNF24 RASSF2 PANK2	down	*
GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN	0.0032062	0.0167602	0.4317077	-0.2642823	-1.404044	179	PECAM1 USP12 COQ2 STXBP6 CCDC88A SFR1 MANBA TEX2 SLC36A4 SERINC1 SLAIN2 EPB41L2 TM6SF1 CAPZA2 RPF1 ZNF706 UTRN SRSF3 PPA2 SNX29 TYROBP VPS26A STX7 CREB1 ATP13A3 SLC10A7 DOCK8 MORF4L1 CWF19L2 PELI1 ZFAND6 AZIN1 COPS3 TERF2IP C8orf37 KTI12 GEM CYB5R4 NHLRC3 STK4 CUL3 JMJD1C AIM2 TRAPPC11 CNOT8 NUP160 MAP4 HERPUD1 PHYH SPPL2A ATF2 CSNK1G3 SRSF11 C6orf62 METTL25 MEF2D ATF6 CAPN7 AKAP13 IVNS1ABP ZBTB6 SUCLA2	down	*
GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN	0.0043745	0.0217918	0.4070179	-0.2645298	-1.404033	178	USP12 TBX3 LRRC8C RAMP2 CALCRL YPEL5 NR3C1 DSCAML1 PSMD5 USP47 SLC11A1 SERINC1 ZNF503 SERPINB9 RBM4 FAM122A UBE2D3 IL10 PTGIR VASP MYO1B ST7L GPR85 M6PR CLK4 FCER1G KBTBD4 KREMEN1 TDRD7 SLC25A25 COPS2 RNF141 ATP6V0B DNAJA1 HSD17B12 MORC3 TPP2 PXK MOB1A PELI1 MAPK8 AZIN1 ZBTB1 TSC22D1 HNRNPH3 GEM ICAM1 RIPK2 ARL14EP G3BP2 NFKBIA TTC28 IAH1 PUM1	down	*
GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP	0.0035682	0.0183574	0.4317077	-0.2642469	-1.403623	177	TMEM126A TRPV2 INSIG1 LPL LY86 CCDC88A BMPR2 TET2 IGSF6 METTL23 ABCG2 ITGA5 FZD4 SLC25A37 AKT3 SAP30BP NOSTRIN STX3 NR1D2 TLR4 TM6SF1 CD300C IL7R TMEM9B COPS2 DCTN6 OASL RWDD1 GLUD1 OSM HSD17B12 RNF24 NAA30 DENND4A ZCCHC9 TMEM192 RBKS BTBD7 PARD6A ZBTB11-AS1 LGALS3 IST1 CCNH TNFSF9 PAIP2 GRPEL1 SLC35A1 SNRPG FKBP1B CLOCK DRAM2 CBR4 DNAJB4 LAMTOR5 WAC TSC22D2 CAPZA1 MAP3K1 TAF1D FNIP1 MRPL16 PEX13 METRNL BTBD1	down	*
GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_DN	0.0066279	0.0304923	0.4070179	-0.2712699	-1.403145	150	SLPI CD300LF LPXN TRPC3 HCAR2 CCRL2 GIMAP6 IL1RN APOD PLA2G7 SGMS2 SRGN FLI1 DRAM1 RMDN3 CCL3 ATF3 HOPX AXL CD53 PRF1 SH2D2A IL2RB STAT4 RAC2 IFNGR1 PTGER4 CCR7 TBX21 CST7 TIGIT CD74 BIN2 CD6 PIM1 GEM SELPLG IL18RAP LAT HAVCR2 TRAF1 AIM2 GPR171 NRG1 GIMAP4 CSF2 JDP2 NR4A2 CLEC4E ICOS ITGAL SH3GLB1	down	*
GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN	0.0028426	0.0152525	0.4317077	-0.2665431	-1.403031	170	FGD5 RASIP1 CYP27A1 LPXN BMPER INPP5K ESAM C3orf70 UBL3 SLC7A7 TMEM204 TFEC SPI1 TCF7L2 CST3 SNED1 BIRC2 EPOR CASP1 PLEKHM3 OSTF1 DRAM1 TPP1 ITGAX CXCL2 C9orf72 FRMD4A RUFY3 CD8B IL6 SYNPO2 LRCH1 SLC16A11 CSTA SNX2 FBXL16 PSTPIP2 GRB2 NPR1 THSD7B RALB CGGBP1 SIGLEC1 YPEL2 STXBP3 CD1D TEX14 TBRG1 RELL1 ATP6V0C GNB4 ADAMTS15	down	*
GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN	0.0066279	0.0304923	0.4070179	-0.2712071	-1.402820	150	SIRPB1 EPAS1 AKAP5 ABHD5 PTPRE RASAL2 SLC39A8 S1PR1 IL1RN HBEGF ADAM17 EVI2B IL10 SDCBP REST CCL3 SELL SELP CCL4 PLEKHB2 ALOX5AP EVI2A TP53BP2 SACM1L CD8B LRCH1 KCTD12 TMPRSS11D KLHL18 GPR183 PTGER2 LSM1 CGGBP1 SLC25A24 NAPG WNT11 BCAS2 ITGA9 KHDRBS1 CT62 IL18 IL18RAP	down	*
GSE17721_CTRL_VS_POLYIC_8H_BMDC_DN	0.0056582	0.0268944	0.4070179	-0.2679001	-1.402684	160	SLC6A4 SLC47A1 PTPRE CAV1 DYRK1A MSLN IL1RN CCNL1 PPP1R15B TTYH2 M1AP BFAR SERPINB9 CRK SGCA STAT5A BNIP2 TACR2 DAB2 VRK2 GCA SPRYD7 CA1 PROCR MCMBP MOB4 ADCY2 DDHD1 ETV3 NOTCH1 RHOG CRYM HOMER1 OCIAD1 BLOC1S6 FLNC STXBP3 HSPA2 SLC31A1 SERTAD1 G3BP2 ARPC5 KLRK1 CYTH1 HAT1 GPN2 FHL5 CD70 ENDOD1 CRBN	down	*
GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_UP	0.0065573	0.0302528	0.4070179	0.3128663	1.402367	170	SPATA24 HELLS CCDC34 DROSHA CHCHD6 FLAD1 ACAD9 ALDOC DTL COQ3 COX11 PRKDC WDR60 AHCY TST MRPL37 POLE2 GDPD1 VANGL2 PRPF6 BPGM PIAS3 DPP3 PSMA5 MRPL52 MTA3 LRWD1 ZSWIM1 CENPM RPA1 ODF2L MCM5 HIBADH ROMO1 PIGX CCNG1 C1orf122 STRBP INTS8 PRIM1 CISD3 ECH1 SCNM1 PRPF31 TRIP4 ZNF217 GTF3C5 AGBL5 NUBPL VDAC3 TNS3 TONSL SPR LRSAM1 NMT1 TMEM256 CDKAL1	up	*
GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN	0.0054349	0.0259849	0.4070179	-0.2670997	-1.402315	167	ACP5 FAM167A VAMP2 YPEL5 MAL GIMAP6 ANXA1 DPEP2 C1orf21 ADRB2 PDE4D SORBS3 EVI2B TLE4 AHNAK KIAA0513 ID3 LAPTM5 PDE3B NR1D2 PNRC1 SMAD7 IL7R C16orf54 CREBRF S1PR4 KLRB1 GIMAP2 EPC1 PIK3R1 TNFRSF10B YPEL2 MBP GIMAP1 EHD1 APBB1 HBP1 RIMKLB RGS2 CLEC2B SESN1 TFPI CXCR4 CDKN1C CAMSAP2 GIMAP4 HPCAL4 ARRDC2 JMJD1C-AS1 FAM8A1 PLEKHA2 SLC26A11 MICAL1 ATP2B4 MAP3K1 MEF2D CSF3	down	*
GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_DN	0.0044268	0.0219853	0.4070179	-0.2641557	-1.402047	178	USP12 PTPRE RCOR1 BAIAP2 MOB1B RBM7 TRA2B PPP1R15B EIF5 CSGALNACT2 KLF10 MED19 NR4A1 ZEB1 EXOSC9 EIF1B CSRNP1 COQ10B ACTR3 SNORA28 ZBTB43 DNTTIP2 EVI2A SLC25A32 RSL24D1 MIR17HG PNO1 NECAP1 PPP1R15A CD83 KBTBD8 CAP1 TCP1 AGFG1 YTHDF3 RUNX3 PEA15 NPTN GTF2B ARAP2 MIR155HG IER5 HSP90AA1 TAB2 NUP98 TRAF1 TMX2 NAA15 GSPT1 PURB SPHK1	down	*
GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_2H_UP	0.0031515	0.0165721	0.4317077	-0.2652251	-1.401023	174	HMOX1 MS4A7 KCTD9 INSIG1 SH2D3C LONRF1 ARHGAP29 TNFRSF8 SLC44A2 NAAA RNF144B PAG1 SLAIN2 TCF7L2 TFRC SNED1 PER3 REST KLF11 ZFAND5 UBQLN1 LBH ACTR3 SFTPD DSTN UBASH3B HES1 IKZF5 ARHGAP17 PDK4 RNF149 SNAP23 JPH1 JAK1 CAP1 VMO1 CD7 PRORSD1P SNX9 RRAS YPEL2 XYLT1 PIK3AP1 ZBTB11 PHF19 MFSD12 ARAP2 SESN1 KPNA4 ULK2 DAPK1 ING2 ABI3 CTSC NDUFAF5 MIS18BP1 FAM13A-AS1 ITGB1 HES4 CD79B MTSS1 GPR137B ARHGEF12 TES SMARCA5 GRPEL2	down	*
GSE3982_BCELL_VS_TH2_UP	0.0092623	0.0394625	0.3807304	-0.2672983	-1.400908	159	ACP5 FCN1 WFDC1 LTA4H LYL1 PLEKHF2 LMO2 SLC15A3 FAM49A DPEP2 SLC7A7 MCL1 PPP3CC EFCAB14 YBX3 DENND3 TPP1 MYO15B PNRC1 DUSP1 ARL4A N4BP1 RAB6A PKIG HESX1 IL6 GABARAPL2 AQP3 CD48 ARHGEF10 TMEM251 PODXL IRF8 CDK14 TNFSF13 TFEB VAV3 PDLIM1 MIA3 HBP1 TAGLN TXNDC15 EPN2 CREBBP GLUL KLRK1 DAZAP2 C1orf115 RABGEF1	down	*
GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0050319	0.0244176	0.4070179	-0.2644403	-1.400877	175	SC5D LPIN2 ADPRH TMEM170B CD44 LONRF1 AKAP7 BCL2A1 ADAM17 CYB5A ZDHHC2 HSPB1 CYP4V2 IL10 MAP2K3 FABP5 STAT5A ST3GAL2 ITM2B KLF9 SSH1 HOPX RECK ELK3 MATK VAMP5 MYO1C PHACTR2 NEK7 RAB8B CD48 OSTM1 IFNGR1 COBLL1 HOMER1 NDST1 AGFG1 RIN2 CCR4 SAV1 TGIF1 IFNAR1 PIM1 CD81 STON1 GEM SESN1 IL18 MIER1	down	*
GSE39820_IL1B_IL6_VS_IL1B_IL6_IL23A_TREATED_CD4_TCELL_DN	0.0066596	0.0306092	0.4070179	-0.2677223	-1.400507	158	RAMP3 DENND5A PHYHIP GPR65 JPH4 CD44 PPP4R1 IDI1 S1PR1 STX11 NCF2 IL1RN STARD4 LTBP4 C1orf21 ZDHHC2 NR4A1 PDGFA FABP5 AHNAK MEFV PRKD3 ABCC4 VIM ELK3 SMAD7 EVI2A MBD2 SLC6A6 PROCR INPP5B MED30 JPH1 RABGAP1 AK1 PTGER4 GPR183 FAM43A COBLL1 TSSK6	down	*
GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_1DAY_STIMULATED_BCELL_DN	0.0071344	0.0321543	0.4070179	-0.2699623	-1.400254	151	SIGLEC11 EREG PID1 FOLR1 AATK SFR1 FAM49A TBX2 TNFRSF8 CORO6 CARD16 ADA CHRNE RBM4 PDE4D CASP1 BST1 STK17B THBS1 MED6 VRK2 ATG7 ERP44 TMEM255B HPSE B9D2 DSE PIK3R5 DCHS1 TANC1 WNT9A DDX60L	down	*
GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN	0.0057454	0.0272292	0.4070179	-0.2669986	-1.399995	166	SLPI SLC31A2 ACVRL1 CD52 OSBPL11 HVCN1 DPYSL2 LY86 INPP5K CITED2 TBC1D2 ANXA1 ATP2B1 ANXA5 STOM CD93 EVI2B MSR1 ZCCHC24 SLC7A8 CEBPA VIM PAPSS1 HOPX HPSE ALOX5AP MPC1 ANXA3 TDRD7 PGD SERPINB8 RAB31 VPS26A GLIPR1 SDHD GPR183 TAGLN2 RBKS LGALS3 ICAM1 ANKLE2 RTN4 CEBPD TIAM1 SEC61B NLRP3 PSME4	down	*
GSE15624_3H_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_UP	0.0098504	0.0412294	0.3807304	-0.2688471	-1.399683	156	IL17RB SLC16A4 PDE1B MTMR10 CTDSP1 TGFBR3 NEDD9 ARHGAP29 SEMA6D ATP2B1 ACOT2 ABCG1 IL18R1 SPI1 CDADC1 CCL22 CTSD RBMS1 HOPX MATK BACE1 IKZF5 SEC31A CDKN2AIP TMEM9B S1PR4 DDHD1 IL2RB MITF C20orf194 RAC2	down	*
GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_DN	0.0046364	0.0228398	0.4070179	-0.2636466	-1.399345	178	LPIN2 ENDOU INPP5K SAMHD1 GPCPD1 BMPR2 SYS1 TGFBR2 TXNIP PAQR3 CRK EPM2AIP1 CCNI TAPT1 DUSP3 SCP2 TCP11L2 HPSE PNRC1 LBH CLK4 LMBRD1 GLB1 CLN8 NCKAP1L TECR GZF1 SNAP23 CABP4 HCFC2 SF3B1 DDX17 UHRF2 PPP1R15A RAPGEF1 UBAC2 MBNL2 CDK2AP2 SLC25A24 ECI2 FOXO3 CHPT1 PHF3 COPS3 TSPAN14 MIA3 HNRNPH3 TOB1 HINT3 IL18 ALDH2 PSME4 ING2 PAIP2 EHD4 EVI5 SETX SVIL ATF2 CMPK1 ALG2	down	*
GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_UP	0.0060588	0.0284651	0.4070179	-0.2672587	-1.399326	160	ACP5 TSPAN4 LIPA EGR2 LY86 NUDT9 EIF4A1 HBEGF SLC7A7 NMUR1 HLX SIRPA GRN APOC1 SETD3 MTHFR MPEG1 PLAUR USP2 PLBD1 ATG7 LAPTM5 COTL1 AXL HCK NCKAP1L CD48 HMBOX1 ST6GALNAC4 TYROBP ELP5 GSTO1 TPRA1 PLCG2 SLC3A2 PRKCG IRF5 TFEB	down	*
GSE27786_LSK_VS_NKCELL_UP	0.0108425	0.0439473	0.3807304	0.3134160	1.399211	164	CCDC34 UBE2T GPATCH1 CA12 CCNF SRPK1 C6orf132 RUVBL2 BOD1 THBS4 TMEM177 TTLL12 RAD54L TOPBP1 CSRNP2 ZNF48 GLE1 DDX56 FGGY NCAPG2 TMEM106C CENPH SSX2IP POLR1C HMGXB3 ABHD4 FOCAD ST14 CDC23 PUS1 TK1 CASP7 MLEC C12orf73 MAT1A CENPV SIRT4 RRP9 RPUSD1 SRRT WNT10B PEX5 TDP1 LANCL2 HAGHL GADD45GIP1 EARS2 TRIB2 MTHFD1 PAICS E2F7 TMEM42 CLNS1A PAQR8 ZNF319 PDXP NSUN5 AKAP9 KIFAP3 STARD10 PCBP4 TIPIN RETSAT TXN2	up	*
GSE22935_UNSTIM_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN	0.0086503	0.0374614	0.3807304	-0.2658182	-1.399030	169	GPR15 TAL1 CPEB2 PTP4A2 GPR65 MIR22HG ENG ARL8B DYRK1A HPS5 ARHGAP10 FBXO7 B3GNT5 C16orf89 ABCG1 PAG1 ITPRIP TPSG1 THBS1 SIK2 DSE SMNDC1 MAPRE2 PROCR ARHGAP17 FRY CTSS KCTD12 RHOG GSTO1 REL RNF24 ATP6V0D1 YPEL2 RUNX3 CD74 C19orf38 CPA3 NIPA2 KIAA0232 TGIF1 SH3RF3 TAGLN TPT1 PTCH1 KATNA1 KIT CECR2 P2RX1 FGFR1 NRP2 PAPSS2 EIF4G2 ZFYVE26 CLOCK C16orf95 OSGIN2 PDCD2 RNF112 TSC22D2 ACTR1A NMI ZNF347 DR1	down	*
GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_DN	0.0032557	0.0168922	0.4317077	-0.2647824	-1.398684	174	DENND5A IL1B SLC6A12 INPP5K OTUD4 FAM49A LRRFIP2 EIF1 AKT3 SRGN ARHGEF2 BTG3 TXN TBC1D9 SYNPO PTGIR CCL22 FOXO1 FUT7 STK17B KLF7 MYO15B NFKB1 UXS1 CCSER2 DUSP1 PLEK SLC25A32 MPC1 RUFY3 TDRD7 RAB8B MAP4K4 DNAJA1 CSTA JAK1 REL GTDC1 UVRAG RASSF2 DENND4A GRSF1	down	*
GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP	0.0030475	0.0161034	0.4317077	-0.2655747	-1.397933	170	ADCY9 RCOR1 MMRN1 CITED2 AQP9 ZCCHC2 MKNK1 TGFBR3 CD9 MOB1B STARD4 NLK RNF125 SPIRE1 DACH1 PTPN12 PER3 EPOR PIP5K1B FAM76A KLF11 TJP1 MPL ZBTB43 VAMP5 CA1 VWF CREBRF UTRN NDNF CPEB4 OSTM1 ENPP4 GYPC FRYL SLC25A24 ZBTB11 HACE1 YAF2 EPB41L5 GIMAP5 SIK3 P2RX1 CCND3 GRB10 MT2A WDFY3 GHR SH3GLB1 RAB37 PLXDC2 CCNT2 OTUB2	down	*
GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP	0.0030475	0.0161034	0.4317077	-0.2655064	-1.397573	170	CD300LF ZMYND15 OLR1 TMEM52B CD55 IL1B CYP27A1 TIE1 GFOD1 PRAM1 GTF2E2 TMEM138 TBC1D2 AGPAT4 FGR PTS SLC36A4 CYB561A3 ABHD6 LAIR1 ANKRD29 EIF1B LCMT2 BST1 CDKN1A N4BP2L1 FKBP15 CD300LB SNN MTMR14 SMIM20 TAGLN2 ACSL1 POGLUT1 SIGLEC17P RNASEK HIVEP2 CR1 FXYD6 DOK3 CD1D TMEM230 LRRC32 APLP2	down	*
GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP	0.0060893	0.0285560	0.4070179	-0.2678367	-1.397503	168	OSBPL11 FABP4 THBD AATK BACH1 MYD88 VAPA SLC11A1 CIT KCNK3 MAP3K8 HLX PAG1 FBXO8 HNRNPA3 ZFAND5 FAM49B PDE8A ERP44 SELP CCL4 GNAQ TANC1 CMTM6 PROCR BTG1 RNF149 IL6 PSEN1 SOCS3 IL2RB CTSZ JUNB MTMR9 RCAN1 PPP1R15A PTGER4 NAA30 TUBGCP3 AGFG1 GNAI1 CD86 PDCD1 ORC2 MEIS1 RGS2 IST1 BMP2K FKBP1A CEBPD CYB5R4	down	*
GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP	0.0042131	0.0211173	0.4070179	-0.2628219	-1.397347	180	EPAS1 SC5D PTP4A2 GPR65 FIG4 CD44 PPP4R1 CORO1C TRIB1 ABCB1 LRRFIP2 KLF10 LCP1 PDE4D TFRC PDGFA VIM DNTTIP2 ELK3 ZMPSTE24 RAP1GDS1 TP53BP2 CMTM6 HGSNAT SRF ETF1 SLC25A3 CRNKL1 RAB8B SRSF3 SF3B1 GABPA RAC2 RPL9 FBXO11 THUMPD1 ATG3 HNRNPD CPA3 NAB1 TCF7L1 MR1 RPP30 WDR1 CEP170 TPT1 HSP90AA1 PTCH1 G3BP2 ITCH PSMD6 HNRNPH1 EXOG TMEM50A DUSP6	down	*
GSE360_DC_VS_MAC_L_DONOVANI_DN	0.0030475	0.0161034	0.4317077	-0.2654100	-1.397066	170	ACP5 USP12 CD55 MNDA RDX FYN LPL LY86 ST3GAL6 MYD88 CD9 SLC11A1 EPB41L3 NUMB SLC7A7 KLF10 RNASE1 TPP1 PDE3B ATF3 CTBS ADIPOR2 CUL5 OXSR1 RPS6KA2 METAP1 MUC3A NSMAF BTD IDS PTGER2 CDK2AP2 STX5 RPS6KA1 TNFRSF9 CLN3 MSMO1 AZIN1 GSAP ZBTB1 TSC22D1 PIK3C3 CCR1	down	*
GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_UP	0.0065953	0.0303997	0.4070179	-0.2662525	-1.397024	161	LYVE1 RAMP2 THBD LONRF1 YPEL5 B3GNT5 LHX6 NDEL1 MTMR6 TLE4 SGTB COQ10B ZNF24 FBXL3 DNTTIP2 BCLAF1 ANXA3 PI4K2A RASGEF1B TOPORS CREBRF ETF1 DCP1A PPP2CA PLEKHA3 MED30 MN1 FYTTD1 PNPLA8 HSPA13 KBTBD8 TMEM167B NUDT15 YTHDF3 ING3 ZRANB1 ABHD13 DPM1 MAP3K2 GABARAPL1 CRY1 GNA13 CLEC2B GTF2B SLC34A2 NUP98 B3GNT2 DNAJB9 TLK2 SAMSN1 RAB2A TBPL1 USP30 MZT1 FAM8A1 CYB5R2 IFIT5 SPTY2D1 LAMP3 TMEM11 ESCO1	down	*
GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN	0.0027869	0.0149865	0.4317077	-0.2624315	-1.396631	184	SLC31A2 SASH1 ADPRH CLDND1 SLC10A1 LMO2 PPP4R1 KIAA1109 BMPR2 HEG1 FBXO7 PPP2R2A DACH1 RAB14 PPP3CC MTMR6 BIRC2 STK17B MYO1B RBMS1 ATF3 AXL CCSER2 GCA N4BP1 TDRD7 HCK RBPJ IL6 RBM34 OASL DNAJA1 DHX15 MALT1 RALB CGGBP1 ACSL1 CDK17 HIVEP2 MYL12A RIN2 STRN SRSF4 SERPINB1 FPR2 CD86 MEIS3P1 CCR1 MACF1 GTF2B AMD1 ARAP2 ABL2	down	*
GSE25087_FETAL_VS_ADULT_TCONV_DN	0.0103424	0.0425574	0.3807304	-0.2681431	-1.396017	156	HSD17B11 RBM14 FBXO3 TXNIP MALAT1 TM2D3 ADAM17 PBX3 LITAF FOXP1 TLE4 FOXO1 TCP11L2 KLF9 HPSE GPR157 KANK1 MYLIP CREBRF RGS18 HELQ DUSP8 ZNF540 FBXL16 SNX1 APH1B PANK2 CELF2 CWF19L2 BIN2 ZFYVE9 SH3RF3 IRS2 EXOC1 MEGF6 TSPO ALDH1B1 SCPEP1 ANKRD49 NHLRC3 TMEM87A NR3C2 IAH1 BMI1 LYZ MED31 KMT2E SLC26A11 PATL2 MICAL1 FXYD5 SNX14 ABHD14A	down	*
GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN	0.0035979	0.0184711	0.4317077	-0.2622533	-1.394954	187	SIDT2 PPARG CPEB2 LTA4H USHBP1 RAMP2 LMO2 SOX17 CAV1 GAS6 SLCO2A1 PDE2A LACTB PCYOX1 C16orf89 CAV2 ADIPOR1 SPTBN1 EVI2B KIF1C DUSP3 PAPSS1 ELK3 ADIPOR2 KLRD1 FAM76B HEXB S1PR4 AK1 PODXL RPS6KA1 PRKACA NDST1 TPRA1 MBP CD74 ZNF521 TGFB1 TSC22D1 THAP11 RGS2 ABI3BP GSTM5 TIAM1 PIP4K2A ALDH2 CCR9 ULK2 SREBF2	down	*
GSE11924_TH1_VS_TH2_CD4_TCELL_DN	0.0081502	0.0358375	0.3807304	-0.2660429	-1.394742	163	RBP4 SLPI STAC PPARG GPC5 ST3GAL6 NR3C1 NUMB MMRN2 SDE2 RAB33B CSGALNACT2 MTMR6 NPNT CASP1 CEBPA LY96 ITGAX SIK2 VAMP5 NUS1 AFF1 USP16 GLB1 PPIL4 TFAP2E GZF1 FAM189A1 BCAR3 PSEN1 FYTTD1 SNX2 HSPA13 HSD17B12 TMEM167B GTDC1 GFPT2 RALB WDFY4	down	*
GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN	0.0087503	0.0377604	0.3807304	-0.2670612	-1.392639	152	GCOM1 SC5D TMEM52B CYP27A1 TUBB1 OSCAR SFR1 PAFAH1B2 RBM7 ASAP1 LATS2 GLS AKT3 MCL1 FBXL5 AHNAK VIM UBASH3B MOB3A KCNA5 RBPJ LRRTM2 PRAP1 DDX17 DNAJA1 SKIL GLIPR1 TEX29 MALT1 RC3H1 TSPYL1 CYP4A22 NAP1L5 NUP153 NIPA2 VAV3 JMJD6 ZFYVE9 ZC3H12D ATXN1	down	*
GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_DN	0.0114597	0.0461419	0.3807304	0.3093866	1.392203	179	DDX11 RUVBL1 PAGR1 DNAJC22 EFNA3 HILPDA NPAS2 TOP2A ZNF174 ABCC5 TARS2 TRMT61B TMEM63A FDXR SNAPC4 PARP1 DDX56 CASP6 HARS2 CBX5 ZNF45 CENPJ TCF20 NEIL3 NUP205 TMEM231 CCNE1 DPP3 TUBG1 TRMU LRFN3 AARSD1 MRPS34 HIRA MRPL52 SSRP1 MGMT ANXA9 CLUH AATF ZSCAN16 PATZ1 ADORA3 CCNA2 VDAC1 ETHE1 POLR1B TP53 FIS1 ACAD8 SS18L1 RANGRF CAMK2N1 ATXN7L3B NSUN5 BAG2 RUSC1 TNPO3 FOXRED2 TCFL5 CHD8 RNF8 DCLRE1A RMI1 ORC5 XRCC6 MIEF1 ZNF551 GTF3A KHSRP NVL REXO4 DDX28 PACSIN2 CYP2E1 DNAJC16 LRFN4 GLYR1 CASP8AP2 TMEM80	up	*
GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN	0.0038808	0.0196745	0.4317077	-0.2633711	-1.391229	174	SMAD6 SLC31A2 CCRL2 INPP5A BCL2A1 BRINP3 CLCF1 HBEGF PBOV1 RAP1A BTG2 GLS SLC7A11 PDE4D PDGFA CSRNP1 PLAUR ST3GAL2 DRAM1 SOCS5 PDE3B ATF3 IRAK2 CYP20A1 SH2D2A MAFF DEGS1 HGSNAT LACC1 CLIC5 BTBD18 AREG IL2RB OASL CYB5R1 JUN PTGER4 HOMER1 TNFRSF9 PPM1F PELI1 RNASEK RIN2 CD6 NRN1 ARPP19 RXRA CPQ IER5 TOB2 PSME4 LYST SAMSN1 GRB10 KLC1 EGR1 FADS3 NR4A2 DCUN1D3 ANKS1A	down	*
GSE27786_LIN_NEG_VS_NKCELL_DN	0.0047960	0.0235071	0.4070179	-0.2621045	-1.390988	176	CD300LF USP12 LYL1 CCDC88A PRAM1 BMPR2 CTDSP1 CD22 HPS5 RCHY1 TACC1 NAAA PBX3 ARHGEF2 MTHFR PPP3CC PTPN12 TBC1D9 PTGIR NOSTRIN CDK9 ITPK1 CTBS TM6SF1 SMAD7 INHBA HES1 MARK3 CDC40 PDCD6IP ETS1 ATP6V0B JAK1 ATXN1L SNX1 AGFG1 DGKG SORT1 TFEB VAMP4 C16orf72 ICAM1 ITPRIPL2 RTN1 TRAPPC8 ISCU CEPT1 TMCC3 PURB ATF2 CLOCK ARL4D ATP1B1 FAR1	down	*
GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP	0.0059834	0.0281653	0.4070179	-0.2625736	-1.390988	175	LIMS2 SWAP70 STAC HVCN1 GPIHBP1 ZC3H12C CAT DPYSL2 LY86 KANK3 ADA CD33 C1orf21 ITGA5 AHRR PARVG ITPK1-AS1 NFE2L2 CD93 ARL11 PTPN12 EFCAB14 AMOTL1 LINC00877 SOCS2 IGFBP2 SNN FAM102B FOXN3 CD8B SPIN1 SGK1 SEC14L1 CCDC50 SP3 CREB1 GRASP DLEU2 LMCD1 BCL6B TCF4 PDLIM1 ATXN1 GNB4 ETS2 RXRA	down	*
GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN	0.0077143	0.0342920	0.4070179	0.3100486	1.390825	173	TRIP13 SCIN MEX3A MCM10 TIMELESS CDCA2 CCDC14 BAIAP2L1 KRT16 CDCA8 ESPL1 TFDP2 UHRF1 PLEKHA7 EXO1 SMARCC1 KIF23 CUL7 TP53BP1 EXOC4 RRM2 CDCA5 RHOBTB3 ADM2 LMNB1 CHEK1 CKAP2L PTGDR2 RBP2 CCDC138 PARP1 CBX5 URI1 KRT18 C1orf112 TMEM8B WDR31 DHX33 SPAG5 G6PC3 FHIT KIF22 SCN8A POLD1 MARCKSL1 CENPM ZNF428 NAT8L	up	*
GSE2128_C57BL6_VS_NOD_THYMOCYTE_DN	0.0089355	0.0383219	0.3807304	-0.2666168	-1.390321	152	FFAR4 SWAP70 GPR15 SGK3 HHEX LHCGR SNX10 NUP54 SPNS1 IBA57 SLC15A3 CD22 SLC11A1 ZEB2 LITAF PPP1R13B PER3 TRIM46 ATG7 C1QTNF7 PMM1 ARAP3 WDR48 PI4K2A S1PR4 DDX47 GLUD1 SELENBP1 CAP1 NUDT15 PPM1F GPRIN3 SMPDL3B CC2D2B CD6	down	*
GSE3982_NEUTROPHIL_VS_BCELL_DN	0.0084259	0.0367839	0.3807304	0.3097454	1.390265	177	FGA CPSF6 BET1 PMS2P5 EIF2B5 KNOP1 TOP3B RANBP1 RUVBL2 NDUFB8 ZNF74 GOLPH3 RPAP1 AKAP1 AIMP2 SOX4 FAM162A TRMT61B MGA NAA40 ANAPC5 PKD1P1 MRPL17 TRAF5 RTCB GOLGA3 DPP3 TUBG1 VIPAS39 COX7C HDAC1 PEX10 AAMP ATP13A1 GEMIN6 PTER CPSF4 STOML2 NPRL3 FAM136A LRIG1 POLR3E ABCF2 LPIN1 SUPT3H RPUSD2 PFDN4 PPIA BCAT2 ADCK2 PARP2 AKR7A2 RCN2 CAMK2N1 AVEN WRAP73 BAG2 UTP18 PTPRK RUSC1 DFFB PRPF19 PCNT HINT1 RALGPS2 CRYZ PCBP4 CEP112 UBE3C	up	*
GSE3982_MAST_CELL_VS_DC_DN	0.0069876	0.0316392	0.4070179	-0.2651123	-1.390104	166	GPD1 SLC31A2 SEMA6A KMO RBMS2 DCSTAMP LIPA SAMHD1 RASAL2 NUDT9 IL1RN DDO PILRA LRRFIP2 CD36 ARSB CYB5A ANPEP HLX TUBB6 CCL22 ATF3 CDS2 MATK CLIP4 ZNF706 RAB8B RAB31 GAS2L1 HK3 IRF8 NPR1 SORT1 MCUR1 KYNU ADAM10 CCNH RXRA VASH1 SCPEP1 ULK2 CD1E KIF1B ANXA11 C1orf115 RAP1GAP CTSH MAPK1 KCNJ1 OTUB2 FPR3 LAMP3 SCAF11	down	*
GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_DN	0.0043496	0.0216901	0.4070179	-0.2615849	-1.389483	177	MCOLN1 CPEB2 MIR22HG BACH1 C3orf70 OTUD4 ZBTB2 PEAR1 CACNA2D2 LATS2 KLF6 AHNAK ITM2B KLF9 ROCK1 MARVELD1 ELAC1 ATP6V0D2 PNRC1 DUSP1 PINK1 MATN2 MATK STK24 MCMBP CHDH ETS1 OSBPL9 MSRB3 PIK3R1 DDX5 PTGER2 TPP2 IP6K1 RNF146 CD151 YPEL2 KIAA0232 APBB1 MICU3 RGS2 HACE1 SLC43A2 LDLRAD4 TIAM1 CXCR4 HNRNPK S100A4 METTL7A VSIG10 GLUL LTBP3 RORA NR3C2	down	*
GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_DN	0.0069601	0.0316392	0.4070179	-0.2653279	-1.389217	160	OLR1 SOWAHC PTPRE RGS9 APIP MEF2A MARCO MSLN IL1RN IL23A MYOZ1 KANK2 CNN1 STAT5A P2RY2 ATF3 AQP4 DUSP11 WASF3 MFSD11 PAFAH1B1 RUFY3 MAFF METAP1 RNF149 OASL MTMR14 APBB2 GRIK1 AGFG1 POGLUT1 EMC7 IRS2 CSDE1 WBP2 PDE4B CALB1 ETS2 SMAD2 CEBPD ATP9B BCAM KATNA1 ZFPM2 MACROD2 PPP1CB	down	*
GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_DN	0.0069876	0.0316392	0.4070179	-0.2649328	-1.389163	166	OLR1 CLDND1 CITED2 MEF2A DSCAML1 WBP4 USP47 IGSF6 IL23A CCNL1 WWC2 STARD4 ANXA5 CAV2 NDEL1 TXN PDGFA STAT5A SLC46A2 FAM76A MAFG NFKB1 ID2 CCND2 WASF3 PAFAH1B1 SACM1L MTPN SRF RPS6KA2 PDK4 CHDH PHTF2 SOCS3 PLEKHA3 MTMR14 HSPA1B DNLZ HELQ GYPC	down	*
GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN	0.0080228	0.0354372	0.3807304	-0.2653001	-1.388918	162	SEMA6A MCOLN1 C5AR1 NR3C1 LRRFIP2 SH2B3 BTG2 LITAF EIF4E BTG3 SNED1 SRSF5 NFKB1 CTBS ARAP3 DNTTIP2 SLC25A32 TP53BP2 USP16 TOPORS DCP1A RAB8B NOTCH1 SH3BP5 JUNB RAPGEF1 DLEU2 TSPYL1 CST7 SNRK AGFG1 SLC3A2 SERPINB1 GNG5 APLP2 GATA6 PHF2 SOD3 ZNF143 SF1 IER5 G3BP2 PKNOX2 TMEM87A AIM2 NRP2 RAB2A AFTPH HAT1 CTSH TMEM43 ITGB1 RB1CC1 ECD UBE2W UBE3A AKAP12 PPFIBP1 RAB1A CFLAR IRF4	down	*
GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_DN	0.0080050	0.0354227	0.3807304	-0.2646897	-1.388824	161	SIDT2 MS4A7 SECISBP2L LRRC8C FUCA1 FRAT1 NFATC3 DNAJC3 CHMP1B SERINC1 CYB561A3 AKT3 SRGN ZSWIM6 FBXL3 CD53 FCER1G AKIRIN1 LMBRD1 ZDHHC20 CREBRF EPC1 AP3B1 WDR7 MOB1A MBP C19orf38 CRYZL1 PIK3C3 RELL1 SERINC3 POLK HACE1 ICAM1 SLC35D2 DCTN4 ACAP2 GIMAP5 FBXO25 BRWD1 SSH2 TBCEL ADORA2A CYBA UBAP1 UBR2 PXMP4 ARL4D HP1BP3 DYNC1I2 SNX14 MFSD1 RNF214 IRF1 TMEM170A GNPDA2 CFLAR PLCB2 DUSP2 ALDH3A2 F2RL2 ITPR2 GTF2A1 TLN1 ERMP1 B2M SYNJ1	down	*
GSE360_DC_VS_MAC_T_GONDII_DN	0.0088589	0.0380436	0.3807304	-0.2647526	-1.387978	163	CD52 SASH1 FCN1 PECAM1 LTA4H SIK1 INSIG1 RUNDC3B LYL1 FYN LPL LY86 RASAL2 CHIT1 CIR1 BCL2A1 SLC11A1 LMNA ABCG1 AKT3 SLC19A1 APOC1 ZMIZ1 ADARB1 TNFSF12 TPP1 CADM1 PINK1 RPS6KA2 SH3BP5 KCTD12 DNASE2 BAG5 IDS PTGER2 LGALS2 FOS ALDH3B1 TIMP2 PLA2G15 RXRA GEM BNIP3L CEBPD S100A4 METTL7A GLUL BCAT1 ZNF165 CNOT8	down	*
GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_DN	0.0119358	0.0476260	0.3807304	0.3108660	1.387827	164	C17orf75 SEMA4B TBRG4 XPOT COQ3 UQCC1 LDHB BBS1 TPCN1 ZNF146 KIF11 FAM162A MGA PHB C7orf26 COQ9 PLOD2 ITGB8 STEAP3 CCDC88C TMEM79 MRPS12 CPXM1 POLL COG2 LMTK2 DNAJC11 ZNF768 CCDC51 POLD1 COX10 CCT7 SH2B1 FAF1 ARHGAP22 TRIM56 MRPS33 EIF3D POLR3E EIF3K NDUFV1 POLR3B CDK5RAP1 HK2 LPGAT1 RSAD1 TARBP2 SFXN4 RRS1 TMEM201 TMCO6 ERLIN1 SARDH KIAA0586 TPM1 EIF2D PPARGC1B MRPL12 RANBP10 PARL GLRX5 COQ5 RNF40 ARMC6 TSPAN3 UBE3C DHPS MAEA COQ4 SLC4A7 PRKAA1 GTF3A MRPS7 MRPL35 NOD2	up	*
GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN	0.0121816	0.0482509	0.3807304	0.3084018	1.387772	179	NEK2 TTK EIF2B5 ECT2 CDC6 DTL CCT6A XPOT RUVBL2 EXO1 MRPL15 BUB1 POLD2 MCM7 RRM2 LMNB1 AIMP2 LIG1 ZNHIT1 MAD2L1 AHCY PHB ALDOA UQCR11 THOP1 MRPL36 NUSAP1 SSBP1 PSMB5 TRIM41 DDT EFTUD2 DNMT1 MZT2B DPP3 GNPAT COA3 LONP1 MRPL11 NUP85 MARCKSL1 CDC7 TIMM13 POLR2I CCNG1 NUP62 FARSA RER1 HDLBP PDAP1 NDUFA8 CPOX SMC2 NUP93 NCAPH DRG1 APBA3 TOMM40 NHP2 GCSH PPA1 TIPIN ARL1 MTHFD2 BNIP1 PFKL CTPS1 COPS7A ITPA EXOSC7 MRPS7 C1orf174 PRDX2 LGALS1 LACTB2 TARDBP DPY30 PMPCB S100A6 PLSCR1 SSNA1 DDX1 UBE2M NCBP2 MRPS10	up	*
GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP	0.0100744	0.0419151	0.3807304	-0.2656138	-1.387709	154	SIDT2 PTPRE VAMP2 PLEKHA1 CIR1 CDC42 CHMP1B SERINC1 RNF125 AKT3 SYNPO ARNTL FBXL3 PDE3B PAPSS1 PEAK1 UBASH3B ZDHHC20 HEXB USP25 PDCD6IP HMBOX1 NSMCE2 BTD MBNL2 PTGER2 TMEM167B UVRAG MOB1A C19orf38 ZBTB1 CRYZL1 TBRG1 WBP2 MBNL1 HACE1 HELZ RNF138 SLC35D2 PDLIM5 EXOC2 CYB5R4 GIMAP5 FBXO25 CYTH1 ARHGEF18 EPG5 PHYH UBR2 PRKCH TRMT1L XRN2 MFSD1	down	*
GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_UP	0.0056333	0.0268023	0.4070179	-0.2612967	-1.386873	178	LPIN2 USP12 HSD17B11 PSMD5 TRIB1 RCHY1 IER2 TM2D3 ASAH1 RANBP9 BFAR PPP3CA ZFYVE16 MCL1 KDSR COQ10B ZNF24 ABCC4 PDE3B DUSP11 CD53 PPP2R5A TLL1 SIAH1 FLT1 EBAG9 JUNB THUMPD1 MALT1 GTDC1 TSPYL1 DENND4A ASTE1 BIN2 EMC7 VAV3 GPR18 PLEKHO2 KAT2B ARAP2 ESYT1 EPHA4 JMJD1C GRB10 AFTPH PHYH SPSB1 TMEM50A TMEM43 ING1 ITGAL CCNT2 MFSD1 GPR137B ZNF14 ATP8A1 DERL2 IMPACT IL32 FAM89B	down	*
GSE21063_WT_VS_NFATC1_KO_BCELL_DN	0.0114597	0.0461419	0.3807304	0.3079670	1.386653	180	KIF20A CDC45 METTL1 ANLN TRAIP C5orf46 DNMT3B ASPM NNT WDR62 KNTC1 CCT5 AURKA E2F2 CPD MMS22L GPSM2 CDC25C TOPBP1 CKAP2L ZNF48 BRIP1 FLNB TULP3 TMED3 CKS1B HPS4 NUSAP1 DNER CDK1 HDGF ZNF652 AP3D1 GOT2 KIF2A HSPA4L GOLGA3 SLC35C2 TACC3 OSBPL3 SSRP1 KIF20B GALNT3 MARCKSL1 PWWP2A CDC20 PALB2	up	*
GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_DN	0.0120301	0.0478709	0.3807304	0.3084260	1.386223	178	DDX11 MEGF10 PKP2 KCNK5 PPIP5K1 IGF2BP3 MPP6 C21orf58 TSFM CEP70 ARHGAP33 WDR90 TTLL4 E2F2 TTLL12 FHOD3 AHCY ZNF48 TADA2A CCT3 MRPS2 ZNF623 EFTUD2 PELP1 AKR1E2 SATB2 DCAKD SMG5 C19orf47 DBN1 MYBBP1A GEMIN5 TSEN54 ZBTB45 SLX4 RAD50 KLHL23 FAF1 HMGA1 KATNB1 LRRC14 YBX2 USP39 ERGIC1 CELSR2 MXD3 TONSL MTHFD1 PAICS TTC9C SMARCB1 MSANTD4 ACSL5 CEP290 FGFBP3 DRG1 TFG SRM PARL TUBGCP2 EXOSC10 NHP2 KEAP1 KSR1 PSMD3 E2F4 NUDCD1 GLCE VPS4A ZNF235 GGT7 TANGO2 DNAL1 WDR12 SMAD1 ATXN10 PDSS2 ZNF746 IFT74 FAM83G DDB1	up	*
GSE2706_R848_VS_R848_AND_LPS_2H_STIM_DC_DN	0.0060957	0.0285560	0.4070179	-0.2677606	-1.385846	149	CXCL3 IL1A CPEB2 IL1B OTUD1 PLEKHF2 CCRL2 CITED2 BCL2A1 ADA TNIP3 ZNF503 KLF6 PTX3 MCL1 IL10 CSRNP1 AMOTL1 RAB12 DGKE PPM1K KLF4 TNFSF15 CXCL2 IRAK2 INHBA LMOD3 TDRD7 HCAR3 RNF149 SOCS3 OASL MAP4K4 PPP1R15A FAM43A PELI1 PIK3AP1 FXYD6 MIA3 COL15A1 SOD2 GTF2B CCL20 NEK1 MIR155HG	down	*
GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP	0.0091068	0.0389055	0.3807304	-0.2643300	-1.385789	171	SWAP70 FABP4 GPR65 BMP2 KANK3 QKI S1PR1 CD9 TRIB1 NUMB CD36 PICALM LITAF FBXL5 ZMIZ1 EXOSC9 BNIP2 ID3 THBS1 PDE8A PAFAH1B1 SACM1L RBPJ ID4 PPP2CA CREM PIKFYVE SEC14L1 STAT4 PNMA2 LTBP2 HRH1 IFNGR1 VPS26A AK1 DUSP8 ATP13A3 CELF2 HIVEP2 CD86 TERF2IP NPTN ATAD2B CCL20 GEM CEP170 TFPI TRAPPC8 ITGAE PTCH1 THEMIS2 CREG1 TLK1	down	*
GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_UP	0.0083334	0.0365110	0.3807304	-0.2646277	-1.385398	162	OLR1 PHACTR1 CYP4B1 AQP9 CYB5R3 SLC39A8 STX11 BCL2A1 IL1RN CYP4A11 EPB41L3 HBEGF WNT2B GM2A PRELP KLF6 BTG3 PPP3CC VRK2 CCL3 NFKB1 CADM1 SELL HOPX CCL4 PNRC1 BTG1 NINJ1 PLK3 RCAN1 GPR183 PTGER2 MORC3 CST7 GPR3 RHOQ CACYBP DUSP5 CD86 KCNA3 ETS2 NBN TFPI ALDH1B1 NLRP3 USH2A TRAF1 RBMS3 NFKBIA	down	*
GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_UP	0.0102882	0.0424918	0.3807304	-0.2631657	-1.385070	169	SPNS1 HSD17B11 LMO2 INPP5K MYD88 ANXA1 MAN2B1 ENTPD1 RANBP9 RAB14 CWC22 MPEG1 CASP1 ARNTL SOCS2 PLBD1 CTSD HOPX ID2 M6PR PRF1 EPS15 PER1 VAMP5 HLA-DQA1 ACTR2 HGSNAT CLN8 S1PR4 NSMAF NXF1 KCTD12 RAC2 ATP11A UBAC2 RIN2 AP1G1 CD6 NFYC RELL1 DOK2 ICAM1 IL18RAP SFT2D1 G3BP2 KLRK1 RHOT1 NABP1 GIMAP4 IL16 EIF4A2 EIF4G2 CYBA CTSH	down	*
GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_DN	0.0082064	0.0360518	0.3807304	-0.2639350	-1.384864	161	EPAS1 MCOLN1 ENG TMOD3 AQP9 GTF2I NR3C1 GIMAP6 TRIB1 PILRA COQ7 ANPEP TRAF6 LAMTOR3 BTG3 ATP6V1H SDCBP PLAUR COQ10B VRK2 ERP44 ARC ZBTB43 EVI2A KIAA0408 LMBRD1 PI4K2A MED28 SERPINB8 RAB31 SP3 HSPA13 GTDC1 OGFRL1 APH1B CGGBP1 PPP2CB ETS2 PITPNA NBN IER5 GLUL PDE4A MT2A ARFGAP3 IRF2 CYBA TMEM50A CTSH HMGCS1 LNPEP HAS2 MT1E C6orf62	down	*
GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP	0.0049550	0.0241406	0.4070179	-0.2602677	-1.383767	180	GCOM1 PDE1B LY86 SYS1 ABCB1 PDE2A TXNIP SLC44A2 RAPGEF4 REV3L MS4A1 TMEM123 CLK1 MCL1 CCDC82 ITM2B ROCK1 PTPRC VIM DUSP11 TLR4 RNF139 CRIM1 CNOT6L C16orf54 ARHGDIB BTG1 NCKAP1L FRY SF3B1 SNX29 KCTD12 RAC2 JAK1 SNX2 GMFG MORC3 PXK CELF2 HIVEP2 CD74 MARC2 CD1D TEC CBFA2T3 NAB1 CDC42EP3 GPD1L PLGRKT METTL7A PTEN CYTH1 EHD3 SPATA13 IRF2 CDKN1B DUSP6 ING1 SLC26A11 MTSS1 KIDINS220 RCSD1 SGPP1 POLI	down	*
GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN	0.0083621	0.0366038	0.3807304	-0.2645037	-1.383670	158	PRMT8 HCRTR1 CD52 IL1A OLR1 SOWAHC LY86 TBC1D2 ALAS1 MANBA IGSF6 DDO TEX2 PPM1N EDEM1 CLEC7A SPI1 TUBB6 SPNS3 DAAM2 CPVL UBTD1 DAB2 SELL ANXA3 ARHGDIB RPS6KA2 SLC25A25 TYROBP TREM1 DUOX1 STX7 IRF8 PTGER2 FGFR4 NECAB1 C19orf38 ATP6V0C MRGPRF CCR1 ODF3 KIF17 TAGLN TSPO	down	*
GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP	0.0050080	0.0243501	0.4070179	-0.2601483	-1.383132	180	ACP5 HVCN1 TRPV2 SH2D3C CITED2 GTF2I TBXA2R C8orf58 GIMAP6 NFATC3 TXNIP CD5 BTG2 RNF125 GATA3 MTHFR ZYG11B RHOB EVI2B PTGIR ID3 ZADH2 PNRC1 EVI2A N4BP2L1 SH2D2A CREB1 PTGER2 RPS6KA1 RASSF2 SNRK KLF2 MBP TSPAN14 IFNAR1 DOK2 TOB1 RGS2 PDE4B HAUS3 SLC43A2 SESN1 INTS6 CDC42EP3 CXCR4 TDRP FBXO25 B3GNT2 MMD LPAR6 IL16 EIF4A2 EHD3 HSDL1 IRF2 HERPUD1 JDP2 CDKN1B FAM53B ZNF654 DNAJB4	down	*
GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN	0.0090262	0.0386430	0.3807304	-0.2681491	-1.382951	144	SCN4A ST8SIA6 GPR15 RASIP1 KCNA2 SPN TMOD3 S1PR1 TGFBR3 IL1RL1 FAM49A TXNIP ATP2B1 ARSB RAPGEF4 PRSS12 STOM SLAIN2 FLI1 SNAI1 AHNAK FUT7 RBMS1 PLCD1 TECTA MUC3A MAP4K4 SH2D4B ZNRF3 PDLIM1 NAB1 LGALS3 CRY1 KAT2B PDLIM5 MS4A4A ACAP2 ITGAE TDRP ULK2 DAPK1 DOCK10 LDLR SETX CSF2RB CDKN1B	down	*
GSE3982_MEMORY_CD4_TCELL_VS_TH2_UP	0.0097763	0.0411498	0.3807304	-0.2637549	-1.382060	165	SASH1 CD44 KIAA1109 TGFBR2 ANXA1 EIF1 ITGA5 KLF6 CAMTA1 FOXJ3 AKT3 EPM2AIP1 MCL1 ADARB1 CASP1 MVB12B CARS2 N4BP2L1 PAFAH1B1 BTG1 USP25 KLRB1 AQP3 NECAP1 CD48 JAK1 AK1 ACKR3 DDX5 HERC1 POGLUT1 CALM1 FOXO3 TFEB GSAP TSC22D1 MACF1 N4BP2L2 LTBP1 MBNL1 CCR6 SESN1 CPQ PIP4K2A GIMAP5 SIK3 JMJD1C CHCHD7 RORA DAZAP2 TRAPPC11 NR3C2 EIF4A2	down	*
GSE17580_TREG_VS_TEFF_DN	0.0052574	0.0253101	0.4070179	-0.2591278	-1.381870	182	EPAS1 ACP5 ACVRL1 HVCN1 TBXA2R CLEC10A MANBA RAPGEF4 LAIR1 NFE2L2 SPTBN1 SETD3 MYCT1 PRKD3 UHRF1BP1L STK17B CTSD ID2 EVI2A TANC1 S1PR4 WASF2 ETV3 ATP6V0B RAB8A DYM RALB TAGLN2 CD34 ZNF521 NUP153 PEA15 ATG2B TSC22D1 ATP6V1A PDLIM1 CSDE1 MEIS1 ANKRD13A FCGRT ACTN2 ME2 CHURC1 CYB5R4 TXNDC11 TBC1D1 ZDHHC5 RNF38 LYST THRAP3 SMPD1 MAP4 SPSB1 CHP1 SH3BGRL3 HMGCS1 ATP11B ATP1B1 PIK3CG OTUB2 SURF6 NXN	down	*
GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_DN	0.0087279	0.0376972	0.3807304	0.3081006	1.381006	170	SLCO5A1 IQCE BRSK1 NIPSNAP1 STRIP2 SRPK1 B4GALT4 MANSC1 RUVBL2 ZNF862 TNFRSF11A TTLL12 GET4 FBL PPP5C IDH2 DET1 PPIL2 VPS28 MCAT NOP2 ZKSCAN5 DPP3 PDCD11 FANCF SUDS3 LMF1 PDRG1 PARP9 SUPT16H SIRT4 GBF1 ASCC1 STAMBP CELF4 MED24 PRMT1 NOSIP ADD3 EXOSC5 GGT5 ERGIC3 MLLT1 TYSND1 ATG2A RAB43 GMPR2 POLR1A IDUA NELFA ADCK2 ALKBH2 CSTF1 APEH KLHL42 AXIN1 FOXRED2 ZKSCAN4 CACTIN HINT2 ZNF524 HAAO EIF4G3 ELMO2 SLC12A9 POLD3 COPS7A WDR12 GTF3A CHCHD5	up	*
GSE6259_BCELL_VS_CD4_TCELL_DN	0.0059556	0.0280616	0.4070179	-0.2629142	-1.380757	164	SMAD6 WEE1 SWAP70 SGK3 OTUD1 CD8A HEG1 KIAA0355 UBL3 ZDHHC2 TNIP3 ZBTB21 PAG1 AGO4 NRARP ID3 FCER1G ELMSAN1 SPRYD7 GLB1 MTPN SLC25A3 SEC14L1 CD48 USO1 DESI2 MSRB3 DHX15 MCM9 FYTTD1 APH1B SPRY4 CALM1 AZI2 NIPA2 HNRNPH3 HINT3 ME2 PITPNA SEC63 ARIH1 BCAM NUP98 METTL7A KIT ZDHHC5 DNAJB9 ANO6 PXMP4 ITGB1 EYA3 NOG KBTBD11 NOL9 MFSD1 TSC22D2	down	*
GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP	0.0088184	0.0379532	0.3807304	0.3080359	1.380716	170	B3GALT5 CDC45 GMDS NDC80 PHGDH ANLN AP1S1 TPX2 NNT ZWINT CXCL10 AURKA PSENEN E2F2 COASY AKAP1 CDC25C PYCR2 SARS2 RAD51AP1 DCTPP1 TBC1D8 MRPS11 RAD18 MGLL PON1 MRPL36 CDKN2C CD300A ZSCAN25 MAP3K10 RECQL4 CPXM1 LAPTM4B GOLGA3 GALNS SUDS3 CHTF18 CCDC146 SND1 CLTB CKAP2 MALSU1 CUBN RAB3D PRSS16 YIPF2 PRR11 RFC5 UQCRC1 PFKM NDUFA8 TMEM101 TBCB ENTPD7	up	*
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN	0.0082299	0.0361224	0.3807304	-0.2632830	-1.380513	166	LPIN2 CD55 PLA2G10 CITED2 PLEKHA1 SLC15A3 FBXO3 FUCA1 IER2 KIAA0355 CACNA2D2 TMEM204 TOR1AIP1 ZMYM6 RGCC EVI2B KLF7 TMBIM1 NFKB1 P2RY2 CLK4 CD53 EVI2A PPP2R5A MMP19 TMEM9B MYLIP ARL6IP5 OSTM1 ARHGEF10 JAK1 GPR183 RASSF2 APH1B SNRK RRAS BIN2 APBB1 RPL21 SPOCK2 MEGF6 KAT2B CLEC2B PDE4B SLC35D2 ULK2 NEK3 FNBP4 CAMSAP2 GSG1 GRB10 FADS3 AKTIP TGOLN2 FTL FXYD5 ZNF14 SERP1 STX16 KCNAB2 CSF3	down	*
GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_DN	0.0062630	0.0292554	0.4070179	-0.2629199	-1.380370	167	EPAS1 LYVE1 MIR22HG MYADM YPEL5 GNPTAB AGPAT4 ABCB1 ZEB2 ANXA1 ASAH1 ENTPD1 CHRNE PICALM ADRB1 CD93 TFEC ADAMTSL4 MSR1 RAB12 PXDC1 PRKD3 STK17B DENND3 TMBIM1 MGAT4A LAPTM5 CDKN1A ID2 FCER1G UBASH3B CNRIP1 BTG1 CREBRF NECAP1 KCTD12 ATP6V0B PTGER4 SPATA2L OCIAD1 RHOQ	down	*
GSE29618_BCELL_VS_MDC_UP	0.0074660	0.0333097	0.4070179	-0.2645177	-1.380185	168	SWAP70 S1PR1 CD22 GGA2 TXNIP EIF5 MS4A1 JAM3 SPTBN1 CD37 PPP3CC EIF1B SYNPO FOXO1 PIP5K1B GRK5 KLF7 PNRC1 LBH IL24 BTG1 PKIG PHTF2 PIKFYVE AQP3 HECA VAT1 ETS1 MAP4K4 SHOC2 SNX2 CCR7 COBLL1 TSPYL1 IGKV3-20 CDK14 PLCG2 PELI1 KLF2 CR1 PHF3 TERF2IP CD81 KCNA3 GPR18 ISCU CD19 AIM2 EIF4A2 BANK1 YTHDC1 EGR1 NUP88 PLEKHA2 CSNK1G3 CD79B PAX5 MTSS1 GABPB1 TAF1D BBIP1 FCHSD2	down	*
GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN	0.0067806	0.0310188	0.4070179	-0.2618296	-1.380151	172	PTPRE FCER1A CORO1C GAS6 TEX2 DNASE1L3 MAN2B1 ADA SLC7A11 DACH1 LAIR1 IL18R1 GRN TXN CST3 ATP10A DUSP3 KIAA0513 ST3GAL2 DAB2 MGAT4A CD302 FCER1G ALOX5AP DSTN GNAQ TBC1D4 CRIM1 HEXB SERTAD2 KCNA5 PGD ST6GALNAC4 TYROBP IRF8 CDK2AP2 CRYM GRSF1 CD164 MYL12A SORT1 TCF4 DCK DUSP5 FCGRT ICAM1 LDLRAD4 SEC61B ALDH2 TMEM109 DAPK1 CTSC GPR171	down	*
GSE3982_EOSINOPHIL_VS_TH1_UP	0.0103290	0.0425383	0.3807304	-0.2645301	-1.379440	152	PDLIM2 DENND5A CD55 PTPRE LRRFIP1 CD44 PLEKHF2 SPATA1 CD9 FAM49A FGR ANXA1 RAB33B SERINC1 TREH NFE2L2 CLK1 SPI1 HIF3A PTPN12 MOAP1 PTAFR NR1D2 TLR4 PRDM5 IKZF5 CMTM6 TGFB2 TBC1D5 TMEM9B VPS37A INPP5B HECA	down	*
GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_6H_IFNA_STIM_UP	0.0090631	0.0387667	0.3807304	-0.2636571	-1.379241	158	SMAD6 KMO LYPD5 FAM167A RAPGEF2 HSD17B11 OTUD1 ZBTB2 ZBTB4 ASAP1 LMNA OLFML2A LRRN4CL TFEC SOX7 MYOZ3 UNC45B EVI2B AHNAK SELP PTCHD4 HLA-DQA1 TLL1 NCOA1 PRCP WNT9A SNX29 KCTD12 KLHL18 LETM2 HIVEP2 FOXO3 PPTC7 ZRANB1 SERPINB1 BAZ2B GPR84 KCNA3 LGALS3 NRN1 DBNDD2 COMMD9 RTN1 CDKN1C TTLL7 CCR9	down	*
GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP	0.0052056	0.0250856	0.4070179	-0.2615705	-1.379172	173	RAB11FIP1 SC5D PDLIM2 MNDA SIK1 INSIG1 VAMP2 CTDSP1 HMGCR OTUD4 FBXO7 PLXNA2 PPP3CA CLK1 EIF1B SYNPO AHNAK LIN7C KLF9 PDE8A ATF3 CYP20A1 DUSP11 UBE2B DNTTIP2 MAFF BTG1 S1PR4 DCP1A KLRB1 HERC1 CGGBP1 KLF2 MBP ING3 DDHD2 FEM1B MEIS3P1 WBP2 STX12 CLEC2B JUND MOB3B CGRRF1 ARRB2 USPL1 LYST SAMSN1 DAZAP2 NR3C2 TLK1 PUM1 BANK1 STARD13 SH3BGRL3 CRBN NUP88 TUBA1A ZNF14 ZNF154 IRF1 DOCK5 AKAP13 ZNF331 ERLIN2 IVNS1ABP PPFIBP2 SETBP1 ARAP1 INF2	down	*
GSE12366_NAIVE_VS_MEMORY_BCELL_DN	0.0067806	0.0310188	0.4070179	-0.2613762	-1.377761	172	WEE1 MS4A7 RDX BTNL9 FOLR1 GFOD1 NAAA PAG1 SRGN PDE4D CD58 TBC1D9 AHNAK DGKE KCNMA1 PTAFR ARNTL MGAT4A VIM PAPSS1 ALOX5AP PLEK CLIP4 CALM2 EMP3 CD80 VPS37A PHACTR2 TIGD3 IL2RB GPR183 ENTPD4 APH1B ACSL1 TSC22D1 NAB1 ATXN1 CD81 CCR1 KYNU TRAC SLC35D2 ITPRIPL2 CALHM2 IER5 CDC42EP3 PTCH1 SCPEP1 TRAF1 SAMSN1 RORA NABP1 HERPUD1 CRTAP CTSH BHLHE41 CLIP1 PRKCH ITGB1	down	*
KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN	0.0058050	0.0274847	0.4070179	-0.2595712	-1.377544	176	SLPI HHEX IL1B HSD17B11 LY86 WDR74 NEDD4L AQP9 VAMP2 PLEKHA1 INPP5A CD22 GGA2 SH2B3 SLC7A7 TM2D3 ABCG1 FOXP1 ZYG11B RHOB ARRB1 KLF4 RRM2B TJP1 LAPTM5 CADM1 NR1D2 NKIRAS1 SELL PNRC1 CCND2 PER1 SMAD7 IL7R WASF2 RNF141 NECAP1 SLC3A2 GPR3 RIN2 IRF5 TCF4 SBF2 TSC22D1 FEM1B PIM1 CCR1 PDE4B JUND CCR6	down	*
GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_UP	0.0067806	0.0310188	0.4070179	-0.2612824	-1.377267	172	GPD1 RBMS2 RAPGEF2 GPC5 ARHGEF15 SNX32 CTSW BMPR2 ELF2 YPEL5 MEF2A SPATA1 RFTN1 DNAJB14 SEMA6D GM2A RAB33B EPB41L2 CCNI AFAP1L1 FBXL3 FMNL3 ST7L HOPX SMAD7 PI4K2A AFF3 CREBRF COPS2 HMBOX1 C20orf194 USO1 MAP4K4 OSTM1 IFNGR1 ZBTB24 CGGBP1 YPEL2 ZFAND6 HBP1 C8orf37 STON1 TSPO	down	*
GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN	0.0085624	0.0371467	0.3807304	-0.2630163	-1.377113	160	RAB11FIP1 ARHGAP31 ZC3H12C CLEC12A ST6GALNAC3 CDH5 NEDD4L TBXA2R TEX2 ITGA5 BTG2 CLK1 HERC3 ADARB1 ARRB1 SCP2 SLC7A8 ARNTL KLF7 PDE3B NR1D2 CD302 TANC1 CMTM6 BTG1 KIF13A SOCS3 ETV3 MITF NXPE3 DDX5 GPR183 MALT1 FSD1L	down	*
GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP	0.0100524	0.0418592	0.3807304	0.3067800	1.376955	177	HMGA2 EYA1 HJURP TICRR GMDS CCDC34 PSPH CDK4 ASPM PLK1 BCL2L14 PMS2 AACS RCCD1 NCAPD2 WDR90 RUVBL2 PUS7 CENPW POC1A RBM28 SETDB1 CCDC58 DNAJC9 ORC6 BRIP1 FADS2 NAA40 EXOSC2 MERTK ARPC1A C1orf112 KIAA0753 GOT2 L2HGDH NUP205 ZNF324B OSBPL3 PKP4 AGPAT5 KIF20B TWF1 SUPT16H WDR34 CDR2 MGME1 RCC1 CEP152 DZIP3 GRHL1 VDAC1 GTF3C5 NDUFA8 SMPD4 PGPEP1 NMT1 CCDC122 DNM1L CYP11A1 KCNK6	up	*
GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP	0.0104798	0.0429418	0.3807304	-0.2625912	-1.376647	163	CXCL3 ACP5 IL1A ASGR1 ZC3H12C U2AF1 LHCGR WDR74 CITED2 CYB5R3 RBM14 SYS1 IER2 KLF10 DACH1 PPP3CA NR4A1 TCAP CNN1 RHOB IL10 TSPAN12 ST3GAL2 VASP CXCL2 HNRNPUL2 M6PR WASF2 INO80C SGK1 JUNB MTMR9 IFRD1 IDS FOS MBP PKD2 CD74 CHPT1 CTNNAL1 TBRG1 MEIS1 CCR6 GEM	down	*
GSE27786_LSK_VS_NKCELL_DN	0.0067915	0.0310326	0.4070179	-0.2593179	-1.376370	178	OLR1 ST3GAL6 CTDSP1 GIMAP6 SYS1 HPS5 RCHY1 DNAJC3 UBL3 FOXP1 NDEL1 SPI1 TMEM38B PPP3CC EPB41L2 PTPN12 PTGIR CCDC82 MED11 PLEKHM3 CDK9 LY96 RIT1 PDE3B AXL CCSER2 MBD2 PLCD1 NRBF2 MARK3 HEXB CRNKL1 HECA CPEB4 VPS26A MBNL2 GPR183 IDS PTGER2 AP3B1 RBKS SORT1 DCAF5 NAB1 C16orf72 RELL1 GLTP ITPRIPL2 RTN1 OSR1 CYB5R4 TRAPPC8	down	*
GSE5099_CLASSICAL_M1_VS_ALTERNATIVE_M2_MACROPHAGE_UP	0.0069365	0.0315836	0.4070179	-0.2597987	-1.376288	175	LPIN2 CD55 LRRC8C GIMAP8 LIPA SAMHD1 S1PR1 ELMO1 FUCA1 LITAF FOXP1 PAG1 ATP10A FOXO1 GPA33 KIAA0513 DOCK9 COTL1 NKIRAS1 RPL17 BTG1 HCFC2 CD48 GIMAP2 CTSZ SNHG8 RPL9 CCR7 MPZL3 GYPC TPP2 SMIM20 RASSF2 TMEM128 ZFAND6 TSPAN14 MFNG PDE4B EIF3F ESYT1 C17orf49 NFKBIA CEPT1 TOMM5 HEBP1 TLK1 SPATA13	down	*
GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_DN	0.0095206	0.0402783	0.3807304	0.3067306	1.375941	173	TRIP13 ELOVL6 NEK2 CHRNG RACGAP1 ANLN ASPM CDCA8 CDC6 PRC1 DTL KIF23 BUB1 TOP2A AURKA POLD2 CPD CDCA5 MRPL27 KIF11 LMNB1 SOX4 LIG1 KDELR2 CHEK1 DNAJC9 IDH2 CKS1B DRC1 NUSAP1 CBX5 ASF1B CDK1 POLE2 UCK2 BIRC5 ACP6 PSAT1 SSX2IP EZH2	up	*
GSE41867_MEMORY_VS_EXHAUSTED_CD8_TCELL_DAY30_LCMV_UP	0.0120365	0.0478709	0.3807304	-0.2613764	-1.375652	169	SGK3 HHEX GPR65 BMP2 SLC6A12 SAMHD1 SLC15A3 NCF2 GIMAP6 ANXA1 NCEH1 FBXO7 SERPINB9 TFEC SPI1 ATP10A CSRNP1 CASP1 TLR4 PLEK RASGEF1B PIAS1 TDRD7 CTSS JUN CD83 IRF8 SERPINB6 DENND4A OCIAD1 EPPK1 GSAP SERPINB1 TSPAN14 MPV17L NQO2 HINT3 GPR18 ICAM1 SESN1 IL18 IL18RAP IQSEC1 CEBPD BCAT1 NFU1 MTUS1 LYST FNBP1 CSF2 ZFYVE26	down	*
GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP	0.0088628	0.0380436	0.3807304	-0.2625689	-1.374771	160	SLC31A2 SIDT2 OSBPL1A TRPV2 CD44 TMOD3 PRKAR1A AGTPBP1 IER2 RHOA TNFRSF8 LMNA GM2A CST3 ARRB1 SCP2 NPNT LEPROTL1 COTL1 VIM MFSD11 CMTM6 CD48 SNX29 MSRB3 ATP6V0B VPS26A RPS6KA1 SNX9 FOS YPEL2 TEX30 TSC22D1 APBB1 LGALS3 CCR1 PLEKHO2 SLC35D2 RTN4 ARL14EP SREBF2 GLUL	down	*
GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_DN	0.0111475	0.0451083	0.3807304	-0.2684795	-1.374561	140	SASH1 ENDOU IL1B MNDA CCRL2 AQP9 C5AR1 IL1RL1 BCL2A1 NCF2 DNASE1L3 CD33 CLEC7A LITAF SLC7A11 LHX6 SRGN SDCBP ZCCHC24 DRAM1 STX3 LY96 ITIH5 GCA PRDM5 MMP19 PDK4 CTSS LAMB2 TYROBP TREM1 CSTA PRKCE UNC13B APH1B ACSL1 DGKG SOD2 RGS2 NRN1 SLC31A1 PAMR1 PART1 CEBPD CYB5R4 GLUL ARPC5	down	*
GSE22432_CDC_VS_COMMON_DC_PROGENITOR_DN	0.0097019	0.0408889	0.3807304	0.3063972	1.374445	173	PCSK6 SPATA24 KIF20A CDC45 DEPTOR UBE2T PBK PRIM2 BAMBI YEATS4 ECT2 SLC4A3 NNT UHRF1 PRC1 RANBP1 KIF23 KNTC1 EEF1E1 POLD2 RRM2 ANKRD52 ANKRD13B SEC61A1 TXNDC5 ACTL6A RAD51AP1 GLE1 HSPBP1 EXOSC2 UCK2 ATIC OAT NPM3 NOP2 PA2G4 IRF6 MYO19 ESCO2 ATAD5 MEI1 CHTF8 LTV1 ATAD2 GLO1 LHX4 CCNA2 PRPF31 TPGS2 WLS ALDH3A1 SLC12A2 OSGEP RPN1 MTHFD1 ALOX15 MRPL20 RRS1 NAT10 MRPS26 SHQ1 UTP18 PRPF19 HINT1 SMOC1 EMB HSD17B7 WDR5 NCKIPSD	up	*
GSE27786_LSK_VS_MONO_MAC_UP	0.0098474	0.0412294	0.3807304	0.3060236	1.374432	175	CA9 AK4 FBXW8 PHF14 CCT6A CCT2 RUVBL2 CUL9 TP53BP1 EXOC4 NUP155 COASY PRKDC HOOK1 CHD6 ABCB6 TOPBP1 MTG1 UQCR11 PES1 C12orf75 FAHD2A URI1 FAM135A OAT POLR3K PRPF6 PDK1 DENND1A ITPR3 SNRNP25 MZT2B UBFD1 CDC23 COMMD7 DTYMK ITFG2 LRWD1 POLD1 ZBTB45 RRP9 RPUSD1 PRODH MYEF2 C1orf122 RPS26 IL7 BANF1 MRPS25 DOHH TBC1D32 EARS2 TFB1M AKR7A2 ZNF319 MED22 ZDHHC13 VPS16 HUWE1 SDHAF1 KIFAP3 GLRX5 DHRS4 ZSWIM7 CCDC86 XRCC5 RETSAT QSOX2 NUP214 MPLKIP CDC5L SLC29A1 EDC3 AJUBA	up	*
GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN	0.0105957	0.0431715	0.3807304	0.3061816	1.374270	177	HELLS BUB1B CCNB1 TIMELESS PSPH TTF2 NUDCD3 NDC80 GINS1 RACGAP1 TRAIP POLE STIL AURKB SMPDL3A RAD54B XPNPEP1 EIF3B SPDL1 HAUS5 RANBP1 NUDT1 KIF23 RPL39L RGL1 RAD54L AIMP2 SOX4 DNAJC9 AHCY RAD51AP1 IPO9 C1orf112 NEIL3 FGFR1OP PDCD11 TACC3 TUBB2A UBQLN4 PFAS PPP6R1 ZNF160 SNRPD1 HMCES STK39 TSR1 SMARCA4 DZIP3 PRR11 BANF1 LPIN1 GRAMD1B FOXD2 CHD3 SMC2 POLR1B	up	*
GSE17721_POLYIC_VS_CPG_12H_BMDC_UP	0.0041743	0.0209444	0.4070179	-0.2610040	-1.373874	170	CD300LF GLIPR2 TMOD3 MYD88 PCOLCE2 DNASE1L3 RBM7 HBEGF NAAA CSRP1 TTYH2 KLF6 BFAR PAG1 MS4A1 MTHFR ZYG11B FABP5 MED11 STX3 LAPTM5 VIM UBE2B GCA NCOA1 SLC25A3 FLT1 ELF1 BCAR3 STAT4 SNX2 AP3B1 TPRA1 ZBTB11-AS1 HBP1 BRI3 TOB1 KAT2B GLTP SFT2D1 ALDH1B1 NSUN4 TMEM184B PLGRKT ING2 CCDC92 KLRK1 PTEN CHCHD7 RNH1 FEZ2 EGR1 CLIP1 ATP11B MUL1 SGIP1 TOR2A RAD21 PAXBP1 IRF1 NFIL3 KLHL9	down	*
GSE3982_NEUTROPHIL_VS_TH1_DN	0.0105957	0.0431715	0.3807304	0.3060126	1.373511	177	FOXM1 HELLS RUVBL1 ELOVL6 ZDHHC4 NEK2 C17orf75 BRCA1 NOL12 PMS2P5 DGCR8 PTTG1 KNOP1 TOP3B PAFAH1B3 EEF1E1 PUS7 AKAP1 PASK AIMP2 MORC2 ERCC2 ZNF32 CKS1B NEIL3 FADD ANKRD55 RANGAP1 INTS7 LMNB2 OSBPL3 COPS7B ARL6IP4 PINLYP MRPL4 PFAS FAM136A UBE2V2 CKAP2 TDP1 HAX1 C1orf109 LRIG1 UNC119B ABCF2 STK25 SUPT3H SRP9 NDUFA8 ADRM1 MPG DDX52 ROBO1 NMT1 GPN1 NAT10	up	*
GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN	0.0080752	0.0356039	0.3807304	-0.2589124	-1.372932	181	SLC31A2 GPR15 GIMAP8 NDUFAF1 PBX3 PARVG LCP1 RB1 AKT3 FBXO8 CCNI AGO4 DENND6A FBXL3 SEC24B PDE3B GNAQ MOB3A SNX3 PSEN1 UTRN DDX17 EPC1 ZCCHC9 EPC2 ZNF407 RNASEK MBP MYL12A GIMAP1 DDHD2 IFNAR1 BAG6 N4BP2L2 HAUS3 ARAP2 TRAC PCM1 SFT2D1 ARRB2 ACAP2 ESYT1 TAB2 SP100 SSH2 PCBP1-AS1 CCDC92 RAB2B CYTH1 DAZAP2 ELP4 ZFYVE26	down	*
GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN	0.0069876	0.0316392	0.4070179	-0.2604280	-1.372763	172	SLC31A2 SC5D SGK3 QKI FRAT1 GGA2 SLC7A7 MAP3K8 IL18R1 TNS1 GLDN IL10 MOAP1 DUSP3 DAAM2 ZADH2 RMDN3 PLEKHB2 PER1 DUSP1 PIK3C2A N4BP1 PIK3R5 TOPORS LACC1 PDK4 MAML2 HECA STX7 SNX1 RASSF2 PELI1 SIGLEC1 YPEL2 AZI2 YTHDF3 BIN2 VAV3 TAGAP STK40 PLEKHO2 CSNK2A2 ETS2 RLF TFPI PSME4 SSH2 GLUL RNF38 SKI THRAP3 SAMSN1 SLC16A10 STARD13 C1QB ZBTB16	down	*
GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_DN	0.0085716	0.0371536	0.3807304	-0.2647707	-1.372637	146	ANGPT4 SASH1 MNDA PPP4R1 AQP9 P2RY13 BCL2A1 NCF2 CD8A CD33 CLEC7A LITAF SLC7A11 LHX6 SFRP1 SRGN ATP6V1B2 SDCBP ZCCHC24 DRAM1 STX3 LY96 P2RY2 ST7L CTBS CD302 GCA RPS6KA2 PDK4 HCAR3 RNF141 SEC14L1 LAMB2 TREM1 CSTA PRKCE TNFRSF9 DGKG SOD2 PLEKHO2 NRN1 PAMR1 CEBPD CYB5R4 STAM2 GLUL MARC1 ARPC5 CSF2RB C5AR2 CNR2 FTL FPR1 TUBA1A PTGS1	down	*
GSE6259_BCELL_VS_CD8_TCELL_UP	0.0120365	0.0478709	0.3807304	-0.2606700	-1.371935	169	GCSAML OSBPL1A LPXN ADCY9 CLDND1 MEF2A CD9 FUCA1 EPB41L3 RFTN1 ZBTB4 HBEGF TACC1 BTG2 AHRR ZBTB21 SLC7A11 STOM TNS1 TIPARP ZMIZ1 FUT7 CEBPA KIF26A SSH1 ELAC1 WASF3 PPP2R5C LACC1 DDHD1 CABLES1 MN1 JPH1 CCR7 GPR183 SIGLEC15 CLN3 MBP PKIA XYLT1 STON1 KAT2B ETS2 LDLRAD4 SETDB2 SEMA4A PTCH1	down	*
GSE34156_UNTREATED_VS_24H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP	0.0080500	0.0355250	0.3807304	-0.2665226	-1.370609	142	ADCY9 CLEC12A SOX17 RASAL2 CORO1C RTN3 KCNN3 PILRA LILRB3 NUMB CYP17A1 SIRPB2 LATS2 IFI30 MS4A14 LCP1 SIRPA GRN CD58 PTAFR NES UBTD1 PARVB CTSD DSE CRIM1 KREMEN1 CNTF ADCY2 MUC3A KLRB1 PNO1 FERMT2 FAM43A SNX22 CD151 WNT11 IRF5 TMEM230 CD86 PLEKHO2 CCR6 WDR1 RAB5A CDC42EP3 ACTB	down	*
GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP	0.0054854	0.0261753	0.4070179	-0.2577139	-1.369148	179	SIDT2 SASH1 MCOLN1 TIE1 HSD17B11 SOX17 CALCRL NFATC3 PDE2A GINM1 STARD4 C16orf89 GM2A CLEC14A PBX3 PRELP NLK CST3 KIF1C PPT1 SCP2 ITGAX PAPSS1 RECK KLRD1 ADD1 EMP3 S1PR4 KCTD12 RCAN1 SELENBP1 FAM43A SERPINB6 RPS6KA1 DYM PEA15 CBFA2T3 NFYC THAP11 ABI3BP HELZ CCR6 EIF3F GSTM5 CHMP3 PIP4K2A ITGAE ALDH2 CCR9 TMEM109 PALD1	down	*
GSE17721_0.5H_VS_4H_CPG_BMDC_DN	0.0056738	0.0269421	0.4070179	-0.2596308	-1.368945	173	DENND5A CALCRL SLC15A3 DSCAML1 PILRA IL23A ANXA1 HBEGF ADAM17 PPP1R15B ITGA5 SERINC1 PPP2R2A SLC25A37 MTHFR ATP10A CWC22 TJP1 RMDN3 LY96 NFKB1 GPR85 GCA MPC1 AFF1 PLCD1 RPS6KA2 MOB4 SYNPO2 GABARAPL2 MTMR14 CPEB4 ENPP4 CREB1 REL PSMD12 KCTD10 CRY1 KAT2B ETS2 ICAM1 IL18 RTN1 NLRP3 ARL14EP TBC1D1 MAFK EDN1 FDFT1 AIM2 THEMIS2 NRP2 AFTPH TNFSF8 CRBN FPR1 EYA3 MSANTD3	down	*
GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN	0.0057060	0.0270688	0.4070179	-0.2590518	-1.368413	174	PNPLA6 STAC PECAM1 OSBPL1A HHEX RUNDC3B LYL1 EGR2 LMO2 TXNIP ABCG1 PPP1R13B APOC1 FBXL5 ZMIZ1 EXOSC9 MSR1 DUSP3 ZCCHC24 CPVL ITPK1 NPAS3 DUSP11 ACTR3 PINK1 ADD1 HEXB PRCP SERTAD2 KCTD12 DNASE2 PALM PLCG2 CD164 RIN2 KIAA0232 ZBTB1 CTNNAL1 ATXN1 DOK2 NPTN CLEC2B PLA2G15 RXRA WDR1 EPN2 IFFO1 S100A4 METTL7A DAPK1 MAFK CD1E CNOT8 EVI5 ARHGEF18 HERPUD1	down	*
GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_UP	0.0103002	0.0424918	0.3807304	-0.2611292	-1.367083	162	CXCL3 OLR1 IL1B RAPGEF2 MIR22HG MMRN1 CD44 AQP9 CYB5R3 IL1RN GALNT18 HEG1 ANXA1 PLA2G7 BMP1 MAP3K8 PRELP LITAF HLX DACH1 MAPK8IP1 TFRC GPR4 SYNPO EPOR CASP1 PLAUR NFKB1 ARC ACTG2 PIAS1 CAPN11 DHH MTMR9 CCR7 PRKACA TSPYL1 GRIK1 PTP4A1 MAPK8 BCAS2 CD6 DUSP5 ACADL KYNU PDE4B CCL20 SLC35D2 HSP90AA1 SP100 TRAF1 NFKBIA DLST NRP2 MT2A	down	*
GSE3982_MAC_VS_BCELL_UP	0.0103002	0.0424918	0.3807304	-0.2607798	-1.365253	162	GPD1 RBP4 SASH1 FCN1 DLC1 DPYSL2 RASAL2 FOSL1 MYD88 FUCA1 SLC11A1 SCARF1 DDO CIT NUMB BMP1 ARSB PBX3 LUZP1 ZMIZ1 FAM76A STX3 CDKN1A KCNMB1 PAPSS1 TLR4 INHBA PROCR SPIN1 RBPJ FLT1 CREM PSEN1 PHACTR2 RAB8B TREM1 RCAN1 CD83	down	*
GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP	0.0075286	0.0335584	0.4070179	-0.2572136	-1.365201	178	ACP5 PECAM1 SPN LRRC8C LTA4H THBD FYN SH2D3C LONRF1 CYB5R3 AGPAT4 SLC11A1 TGFBR2 PILRA ACER3 SLC44A2 NFE2L2 TCF7L2 CST3 PTPN12 NRARP KLF4 RRM2B VASP TMED5 DENND3 CCND2 FCER1G STK24 PHTF2 SOCS3 TREM1 RCAN1 SKIL IFRD1 SERPINB6 LPCAT2 YWHAZ RRAS AZIN1 ETS2 RTN1 PIP4K2A KPNA4 SREBF2 SAMSN1 MAPKAP1 SPATA13 PIEZO1 NIPSNAP3A HTRA2 ZBTB16 CENPC ITGAL ITGB1	down	*
GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN	0.0065066	0.0301046	0.4070179	-0.2559396	-1.364868	182	NLRC4 CXCL16 PECAM1 KLF13 HHEX PTP4A2 GIMAP8 TMEM170B LYL1 SH2D3C CTDSP1 FRAT1 FBXO7 TACC1 IFI30 GRN MPEG1 TMBIM1 LAPTM5 EVI2A STK24 SNX3 PDK4 RBPJ ARL6IP5 HECA RAB31 DDX17 TYROBP RHOG ZNF555 RPS6KA1 RUNX3 IRF5 TFEB DOK3 DOK2 BRI3 CCR1 THAP11 PLEKHO2 CALHM2 ELOVL1 CXCR4 IFFO1	down	*
GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_RAG2_KO_NK_CELL_DN	0.0104226	0.0427772	0.3807304	-0.2601008	-1.364746	161	LIMS2 HMOX1 SWAP70 TIE1 DPYSL2 PDE1B C5AR1 MAL AGTPBP1 EPB41L3 CRTAM TFEC ZEB1 ATP10A EVI2B BCHE GRK5 KLF7 LY96 DOCK9 FCER1G PEAK1 TP53BP2 DEGS1 EFR3A TGFB2 PDHX CDC40 CAPN11 CD48 ADRA1A CCR7 OSM CXCL5 OGFRL1 GRSF1 MBP MARC2	down	*
GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP	0.0059115	0.0279076	0.4070179	-0.2567636	-1.364100	179	SEMA3G CD101 ACE SNX10 DPYSL2 HSD17B11 GTF2I CDC42 BCL2A1 NCF2 EOGT CCNL1 PBX3 COX18 HNRNPU CYP4V2 UBE2D3 ITM2B PARVB PDE3B NDUFB2-AS1 DUSP1 PPP2R5A AFF1 WASF2 ESD HECA PPA2 DDX17 EPHA1-AS1 SMIM20 RASSF2 USP7 AKIRIN2 HNRNPA2B1 APBB1 EWSR1 CSDE1 FCGRT SMAD2 PET117 CHURC1 CPQ TNFAIP8 NBN ELOVL1 ACTB TTC32 TLR10 NFU1 DAZAP2 MT2A	down	*
GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP	0.0077392	0.0343713	0.4070179	-0.2568368	-1.363201	178	WTIP PECAM1 GLIPR2 TRPV2 PDE1B INPP5K FBXO3 NCF2 FUCA1 TXNIP RRAGC RAP1A NAAA BTG2 CYB561A3 PPP3CA EVI2B DUSP3 TCP11L2 FAM76A THBS1 MAP1LC3B HPSE PNRC1 FAM76B AKIRIN1 C16orf54 AFF3 STK24 NCKAP1L TMEM9B S1PR4 UTRN JUN MTMR14 STAT4 FAM43A ZBTB24 ZNF597 ECI2 DCAF5 VPREB3 IRS2	down	*
GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_UP	0.0062984	0.0293925	0.4070179	-0.2585240	-1.363109	173	ACP5 SIDT2 SWAP70 PECAM1 HHEX CAT COQ2 LYL1 LMO2 SLC15A3 CD1C HPS5 TRIB1 FGR NUMB MAP3K8 MS4A1 ADRB1 TUBB6 RHOB TBC1D9 ADO PIP5K1B YBX3 CDKN1A PAPSS1 PLEK B9D2 SNN PKIG TULP2 SEC14L1 RAB31 IRF8 ZNF804A COBLL1 RASSF2 RHOQ TNFSF13 SAV1 TFEB TCF4 PDLIM1 SLIRP TMEM70 BMP2K OPN3 PARM1 SPIB ALDH2 EHD3 BANK1 RABGEF1 HTRA2 CSF2RB CTSH BHLHE41	down	*
GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	0.0063342	0.0295312	0.4070179	-0.2565632	-1.362809	177	LRRC8C TMOD3 KIAA1109 S1PR1 CBL TMX4 SPG21 TACC1 RAP1A ABCG1 SPTBN1 FLI1 TAPT1 AHNAK ROCK1 ACTR3 UBE2B CD53 PPP2R5A AKIRIN1 LMBRD1 ZDHHC20 HEXB RAB6A CD8B MYLIP TECR STAT4 TTC14 CD7 YWHAZ KLF2 RUNX3 KAT8 C8orf37 DOK2 N4BP2L2 MBNL1 INO80D PITPNA UNC13D TPT1 ARHGAP18 ITGAE UBE2D1 GPD1L COMMD8 CD3G CCND3 TMEM184C ITGAL RB1CC1 COX20 MAP4K2 MTSS1 RCSD1 RCBTB2	down	*
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN	0.0102193	0.0423012	0.3807304	-0.2609452	-1.361545	168	SLPI EREG IL1B PTPRE THBD EGR2 CCRL2 FOSL1 AQP9 S1PR1 TRIB1 PDCL IER2 BTG2 HLX RGCC NDEL1 SLC19A1 MCL1 TBC1D9 PTPN21 LCMT2 MEFV ADO OSTF1 CDK9 CXCL2 SELL CPT1A NRBF2 PDK4 HCAR3 ELF1 SGK1 SOCS3 TREM1 CCR7 SPATA2L CDK14 ACSL1 FOSB MME EHD1 FPR2 PIM1 CCR1 RGS2	down	*
GSE38304_MYC_NEG_VS_POS_GC_BCELL_DN	0.0064389	0.0299334	0.4070179	-0.2561929	-1.360842	177	LPXN CD44 TMOD3 CTSW ST3GAL6 STX11 BCL2A1 PDE2A ANXA1 B3GNT5 ZDHHC2 RNF125 LITAF GRN PPP3CC NRARP YBX3 OSTF1 MAFG ELAC1 HOPX ID2 RECK ADIPOR2 DSTN VAMP5 MAPRE2 IL2RB NDNF ST6GALNAC4 IFNGR1 EEA1 GPR183 PTGER2 COBLL1 C19orf38 SMPDL3B SERPINB1 PIM1 SLIRP DECR1 CCL20 CYB5R4 SEC61B HIGD1C TBC1D1 SCPEP1 TRAF1 METTL7A TMEM109 CCDC92 ADORA2A MCOLN2	down	*
GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_UP	0.0085249	0.0370504	0.3807304	-0.2567726	-1.360257	175	SASH1 SWAP70 DENND5A PECAM1 SPN SLC6A12 RUNDC3B TMEM170B CCRL2 CDC42EP2 ESAM PLEKHA1 ELMO1 FAM49A IGSF6 PILRA ABCB1 STARD9 CD5 CLEC7A IFI30 ABHD6 BIRC2 CASP1 SOCS2 CTSD UBE2E2 SMAD7 ANXA3 STK24 HCK HPGDS NXPE3 RABGAP1 IPO7 UBAC2 NDST1 SNX9 RUNX3 TCF4 TESK2 TAGAP ARAP2 SESN1 RTN1 ARRB2 CDC42EP3 CEBPD	down	*
GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP	0.0084762	0.0369408	0.3807304	-0.2558429	-1.357926	178	CD44 BMPR2 CTDSP1 S1PR1 YPEL5 DPEP2 ASAH1 ADRB2 AKT3 TMEM41B CLK1 EPM2AIP1 CD37 PPP3CC SRSF5 PTPRC CLK4 CCSER2 N4BP2L1 PAFAH1B1 RSRC2 PIAS1 S1PR4 ELF1 STAT4 VPS26A ENPP4 GMFG FOXO3 ING3 ZFAND6 EHD1 NR2C1 CD6 VAMP4 TSC22D1 ZNF136 EXOC1 MACF1 GPR18 CLEC2B RBL2 PTCH1 CREBBP ANKRD49 DAZAP2 ABI1 PSIP1 USP4 CX3CR1 RB1CC1	down	*
GSE17580_TREG_VS_TEFF_S_MANSONI_INF_DN	0.0059192	0.0279171	0.4070179	-0.2576978	-1.356471	170	KRT81 ACP5 RAMP3 ACVRL1 SOSTDC1 CTSW S1PR1 FXYD2 MSRA RCHY1 UBR3 RAPGEF4 PRSS12 NFE2L2 FLI1 EVI2B PRKD3 STK17B KLF7 ID2 CLK4 UBE2B PRF1 PPP2R5A NRBF2 TANC1 SIAH1 TMEM9B MYLIP ARL6IP5 PDIK1L SGK1	down	*
KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_UP	0.0091603	0.0390798	0.3807304	-0.2558972	-1.355620	175	SLPI SWAP70 DENND5A HHEX ZC3H12C IL1B LYL1 EGR2 LY86 LMO2 MYADM CD9 IL1RN CD22 ANXA1 TNFRSF8 ENTPD1 AHRR LITAF HDC PPP3CA AHNAK SORBS1 LAPTM5 CDKN1A ID2 PTGER3 SS18L2 KLRD1 CA1 GNAI2 HLA-DQA1 CREBRF WASF2 EEA1 TTC14 IRF8 GMFG KRTCAP2 CD74 IRF5 TCF4 VPREB3 CD86 CD81 LGALS3 GABARAPL1 ARPP19 CCR6 HSPA2 IL18RAP	down	*
GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_DN	0.0069230	0.0315518	0.4070179	-0.2570668	-1.355426	173	LIMS2 EPAS1 CPEB2 LRRC8C HSD17B6 ST6GALNAC3 EMCN SAMHD1 ZBTB2 NFATC3 DNAJC3 METTL23 MS4A1 LAIR1 PRKD3 ATP6V1D LAPTM5 SH2D2A NRBF2 CRIM1 CMTM6 TAF13 ARHGDIB NINJ1 ARHGAP17 PPP2CA RYBP VPS37A STAT4 DNAJA1 RABGAP1 GYPC AP3B1 PXK MBP TRAPPC10 SYPL2 TFEB AKIRIN2 CD86 NFYC EXOC1 WBP2 SERINC3 ATAD2B GLTP GPX3 LAT INO80 IER5 CDKN1C	down	*
GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN	0.0092662	0.0394625	0.3807304	-0.2556533	-1.354328	175	ACP5 CD52 CD44 TMOD3 TMX4 EDEM1 CD5 RAP1A GATA3 PPP3CA TMEM123 RAB14 EPB41L2 FLI1 EVI2B LIMS1 ITM2B FUT7 CCND2 ELK3 DSTN DEGS1 SEC31A STK24 UFM1 PHTF2 AQP3 HECA ETS1 ATP11A GPR183 PTGER2 TAGLN2 CALM1 HIVEP2 CCR4 MMP15 TPMT NFYC ORC2 SESN1 ACAP2 TIAM1 EPHA4 S100A4 SNX15 SAMSN1 LPAR6 TLK1 EID1 EIF4G2 CDKN1B CAPZB ICOS CMPK1	down	*
GSE339_CD8POS_VS_CD4CD8DN_DC_UP	0.0081263	0.0357647	0.3807304	-0.2578111	-1.353548	167	PTPRB PDE1B PRPF38A NUDT9 CD9 SLC11A1 CD8A DNAJC3 RRAGC SLC25A17 ASAH1 ENTPD1 SERPINB9 TUBB6 STX3 GRK5 KCNMB1 C9orf72 PTGIS VWF PROCR CD8B ETF1 FLT1 METAP1 RNF141 CYB5R1 SLC35E4 LIMD1 IRF8 PTGER2 STX5 KRTCAP2 SPOP EPHA3 CD1D ATP6V1A CSDE1 LGALS3 STX12 ACTN2 IST1 IL18 FKBP1A B3GALNT1 SEMA4A	down	*
GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_UP	0.0075528	0.0336047	0.4070179	-0.2542345	-1.351876	185	EPAS1 GPATCH11 PDLIM2 PECAM1 HVCN1 FBP1 KLHL8 BAIAP2 MTMR10 CLEC10A ELMO1 NCF2 NFATC3 SPCS3 ASAP1 CD33 ZBTB8A SLC19A1 ZYG11B ARRB1 LIMS1 ZCCHC24 ATL3 ARHGAP9 TM6SF1 PINK1 UBASH3B CNRIP1 ARHGDIB FOXN3 TBC1D5 RGS18 CYB5R1 HMBOX1 RAB31 BAG5 GLIPR1 GMFG CTTNBP2 SRSF6 DOK3 NDUFA5 KCTD10 RXRA MOB3B ATP9B METTL21A ALDH6A1 GPD1L FOXJ2 DUSP7	down	*
GSE17721_LPS_VS_POLYIC_6H_BMDC_UP	0.0099016	0.0413729	0.3807304	-0.2551601	-1.351715	175	LRRC8C SLC6A12 CALCRL NUDT9 TSHZ1 OTUD4 USP47 MOB1B ATF7IP2 CHRNE SERINC1 PBX3 LCP1 EIF4E DACH1 NDEL1 MPHOSPH6 AKT3 ZFYVE16 SLC7A2 IL10 MOAP1 CCL22 VASP STK17B TMED5 RSRC2 MAPRE2 SYNPO2 PDCD6IP RWDD1 LIMD1 GABPA INMT RAC2 PABPC4 FSTL3 TSPYL1 TAGLN2 POGLUT1	down	*
GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP	0.0116553	0.0467747	0.3807304	-0.2548599	-1.351443	181	MCOLN1 LTA4H CYP27A1 CAT LIPA PTPRB BMP2 LDB2 CAV1 PCOLCE2 MANBA FUCA1 EPB41L3 TLCD2 GGA2 MAN2B1 NAAA CYB5A CLEC14A ADRB1 ARRB1 DUSP3 SCP2 KLF4 ARNTL PLBD1 CTSD LAPTM5 MARVELD1 CADM1 ITGAX PAPSS1 ARHGAP9 ALOX5AP CD300C VAMP5 ADD1 HEXB CYB5R1 AK1 GLIPR1 CD7 IP6K1 LMCD1 FOXO3 TIMP2 TESK2 TSC22D1 FCGRT RXRA MFAP5 ESYT1 ITGAE ULK2 NEK3 LIMCH1 FOXJ2 FAM13C	down	*
GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0108098	0.0438514	0.3807304	-0.2675135	-1.350979	134	CLEC1B IL1A PECAM1 CAT ENG SUSD2 YPEL5 RAPGEF4 CYB5A ITGA5 PARVG LITAF ANPEP STOM MSR1 STX3 DENND3 FMNL3 MARVELD1 VIM CD302 FRMD4A CD8B HK3 PDE5A CCR7 FAM43A GRASP KLF2 RUNX3	down	*
GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP	0.0073394	0.0329130	0.4070179	-0.2559981	-1.349791	173	SLC6A4 ADPRH RBMS2 LMO2 KIAA1109 NTM NUDT9 ELMO1 NEDD9 ABCB1 RBM7 ENTPD1 BTG2 TTYH2 ZBTB8A RAB12 KLF4 SLC7A8 TMED5 ATP6V1D CLIC4 ATL3 ATF3 CPT1A GNAQ RUFY3 SIAH1 CD80 ELF1 MED28 TAS1R1 DNAJA1 PPP1R15A RAB8A IDNK MORC3 MSANTD2 DOCK8 OCIAD1 TCF4 PDLIM1 TBRG1 SLIRP ACADL	down	*
GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN	0.0074435	0.0332705	0.4070179	-0.2558148	-1.348824	173	CD52 LRRC8C LPXN CD44 BMPR2 LAMP1 NFATC3 FOXP1 TTYH2 CYP4V2 CD37 EVI2B ITM2B LEPROTL1 TPP1 CTSD DOCK9 PNRC1 PINK1 UBASH3B CNOT6L C16orf54 HGSNAT CLIC5 CREBRF CNNM2 EPC1 GPR183 CLN3 ATP6V0D1 EHD1 ATG2B SMCR8 CD6 APBB1 ATXN1 BRI3 GPR18 SERINC3 SLC35D2 ZBTB25 DHRS12 S100A4 TBCEL FNBP4 ZBTB40 SMPD1 ARRDC2 ZFYVE26 CDC14A SLC25A38	down	*
GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_UP	0.0118813	0.0474863	0.3807304	-0.2571409	-1.348098	171	SIRPB1 LIMS2 EREG SNX10 GPCPD1 TGFBR2 SEMA6D CD36 MALAT1 TTYH2 STOM GPM6A ZMIZ1 UHRF1BP1L KLF7 MARVELD1 AXL M6PR CPT1A PTGIS RASL12 RBM39 SLCO2B1 GSTO1 FSD2 SERPINB6 CASZ1 SIGLEC1 CDK17 SORT1 VAMP4 GNAI1 CCR1 HINT3 SOD3 IL18 HTR6 IQSEC1 GLUL ABI3 HEBP1 IL16 MAN1C1 ATP6V0A1 HERPUD1 UBR2 S100A8 PLXDC2 CCNT2 HEY1 C11orf54 CDK7 STARD5 KLHL9	down	*
GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN	0.0105672	0.0431545	0.3807304	-0.2570650	-1.345953	160	SLPI CD52 TSPAN4 LYVE1 DPYSL2 PDE1B WBP4 PPM1D GINM1 JPH2 SH2B3 DNAJC3 B3GNT5 RAP1A DACH1 SFRP1 TXN NPNT MED11 MYO1B FMNL3 SELP AXL PLEKHB2 PIK3C2A ZMPSTE24 TM9SF2 FAM76B TECR RNF149 SNAP23 INMT CD83 UBAC2 N4BP3 PHOSPHO2 PKD2 FLNC PARD6A ATXN1 RGS2 IL18RAP SLC31A1 CDC16 TFPI TPT1 CALCOCO2 TMOD2 NSUN4 PLGRKT	down	*
GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_DN	0.0087872	0.0378863	0.3807304	-0.2531413	-1.345878	180	RAMP3 ARHGAP31 HSD17B11 EGR2 VAT1L GTF2I TGFBR3 BCL2A1 CD9 GNPTAB TSHZ1 TGFBR2 SEMA6D B3GNT5 CYP4V2 TMEM38B TAPT1 TLE4 CASP1 PRKD3 MARVELD1 PDE3B UBE2E2 ID2 EVI2A NCOA1 TBC1D5 INPP5B ETV3 MAP4K4 RCAN1 SERPINB6 CST7 SLC25A24 PPTC7 TRAPPC10 C19orf38 PDCD1 LGALS3 NQO2 MICU3 SEMA4A PIP4K2A LRP12 TDRP STK4 RASSF8 MCOLN2 TOX2 RNF13 USP48 FNBP1	down	*
GSE22935_WT_VS_MYD88_KO_MACROPHAGE_DN	0.0091115	0.0389055	0.3807304	-0.2562646	-1.345835	164	LIMS2 HSPA12B PPARG WFDC1 FABP4 WNT4 USHBP1 LPL AATK KLHL8 ST3GAL6 LDB2 SCARA3 PDE2A TXNIP SEMA6D C1orf21 PRSS12 SPTBN1 CES1 TMEM38B PRCD NPNT PEG3 CLDN5 P2RY2 SIK2 MYH11 PTGIS CLIC5 KCNA5 KANK1 SLC25A3 CHDH ZFP91 SNHG8 PABPC4 UNC13B	down	*
GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_UP	0.0123095	0.0486783	0.3807304	-0.2566914	-1.345742	171	AQP9 GTF2I YPEL5 ZEB2 TXNIP METTL23 C1orf21 ABCG1 CYB561A3 PPP3CA ADRB2 BNIPL ARHGEF2 NR1D2 HOPX ID2 PPP2R5A PEAK1 PIK3R5 INSL6 RASL12 ARL6IP5 CREBRF SGK1 GABARAPL2 MAML2 PDCD6IP LIMD1 JAK1 TBX21 LETM2 IP6K1 RRAS KRTCAP2 KLF2 PEA15 PDLIM1 FCGRT TOB1 MFNG ACTN2 ICAM1 SELPLG BNIP3L SESN1 IL18RAP IER5	down	*
GSE11864_CSF1_VS_CSF1_IFNG_IN_MAC_UP	0.0098241	0.0411902	0.3807304	-0.2557106	-1.342926	164	CXCL3 SWAP70 SLC12A6 MCOLN1 FIG4 LMO2 SFR1 VAPA TSHZ1 GGA2 TNFRSF8 UBL3 SPIRE1 NFE2L2 TNS1 SPTBN1 TFRC AHNAK ID3 SLC7A8 BCHE ATP6V1D ZNF24 ABCC4 ARHGAP9 MATK PEAK1 SLC6A6 LMBRD1 SIAH1 RPS6KA2 CREM SLCO2B1 PHF10 IFNGR1 CREB1 COBLL1 TMEM167B VMO1 MORF4L1 MBP RIN2 TESK2 NQO2 GEM CALHM2 ITGAE ULK2 CEPT1 PDE4A TMCC3 EMC3 ZBTB40 HNRNPH1 MB21D2 SLC19A2 TREM2 HP1BP3 CD109	down	*
GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_17H_UP	0.0118775	0.0474863	0.3807304	-0.2593255	-1.342189	149	SLC24A4 PNPLA6 CD55 IL1B EMP2 AQP9 C5AR1 BCL2A1 PDE4C AGPAT4 RFTN1 HBEGF MTF1 TNIP3 HLX PAG1 DACH1 SLC25A37 CSRNP1 PLAUR ST3GAL2 CXCL2 UBE2B GNAI2 HES1 KREMEN1 BTG1 HRH1 TREM1 GMFG STX5 APH1B AGFG1 LMCD1 NKG7 IRS2 SOD2 CCDC69 IER5 SIK3 TRAF1 MAP3K4 CCND3 ZFPM2 LINC00884 RABGEF1	down	*
GSE15330_WT_VS_IKAROS_KO_HSC_UP	0.0107488	0.0436402	0.3807304	-0.2532524	-1.341609	175	PRX ACVRL1 SGK3 LIPA PDE1B SAMHD1 QKI CTDSP1 ABCB1 RBM7 DNAJC3 LAIR1 SLAIN2 RHOB DENND6A PLAUR OSTF1 SHE ARL4A LMBRD1 TAF13 ARHGDIB RAB6A DDHD1 CTSS JUN ETS1 RAC2 DNAJA1 GLIPR1 PSTPIP2 GRASP USP7 SPOP PEA15 DPM1 NFYC DOK2 MR1 ATAD2B SELPLG RBM18 TBCEL PTEN IL16 HERPUD1 CHIC2 ICOS HLA-DRB1 SGIP1 DAPP1 CAPZA1 CD3E CRIPT FNDC3A NR4A3 PKD1 ZFP1 IVNS1ABP PHIP HBS1L ANO10 RCAN3	down	*
GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_DN	0.0113223	0.0457018	0.3807304	-0.2524175	-1.339745	178	SECISBP2L GLIPR2 IL1B LYVE1 CLDND1 CCRL2 CALCRL PAFAH1B2 VAPA IGSF6 SLC3A1 RAP1A NFE2L2 FOXC2 GPA33 CASP1 PLAUR VASP STK17B TMED5 MYO1B FAM49B RRP8 CXCL2 DUSP11 INHBA HTT HES1 MARK3 NINJ1 WNT9A PPP2CA NXF1 DNAJA1 PTGER4 CCR7 TNFRSF9 RALB CYP4A22 SYPL2 STXBP3 SAV1 GSAP TGFB1I1 STX12 PDE4B TAGLN TNFAIP8 SF1 TAB2 NLRP3 ACTB ARPC5 FDFT1 LDLR GRB10 MT2A GSPT1	down	*
GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN	0.0084846	0.0369408	0.3807304	-0.2540910	-1.339735	173	PECAM1 SOWAHC GATA2 ZC3H12C PDE1B GTF2I NUDT9 KCNN3 NCF2 SLC11A1 SBDS MTF1 MAP3K8 ANPEP NR4A1 EPB41L2 EPOR ZADH2 SCAF4 CDKN1A CXCL2 CCND2 RAP1GDS1 GLB1 TDRD7 MYO1C CD80 HPGDS JUNB IFNGR1 SKIL IRF8 MCAM NAPG DGKG WNT11 EPHA3 SORT1 VPREB3 TSC22D1 CALB1 ICAM1 XIRP1 NFKBIA B3GNT2 ATF4 DNAJB5 GPN2 PIM3 CD70 ITGB1 DAPP1 ARHGEF12 TYRP1 RNF111 CHKA SLC23A2 PTGS2 SRXN1 NFKBIZ	down	*
GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_DN	0.0095797	0.0404440	0.3807304	-0.2533665	-1.338381	174	ACP5 RAMP3 SLC12A6 HVCN1 PTPRE CALCRL GPCPD1 S1PR1 ABCB1 TXNIP SLC44A2 CLCF1 RAPGEF4 AKT3 EVI2B PSTK ID3 IL7R UBASH3B PIK3R5 CD300LB RPL17 S1PR4 ELF1 SGK1 DCTN6 INPP5B UTRN NDNF ETV3 NXPE3 PIK3R1 GMFG OSM TPP2 PELI1 KLF2 ICAM2 RIN2 C19orf38	down	*
GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP	0.0087969	0.0378942	0.3807304	-0.2535823	-1.337053	173	KMO OSBPL1A LMO2 NR3C1 GIMAP6 B3GNT5 MAP3K8 ZBTB8A IL18R1 SPRY2 CYP4V2 MCL1 KIF1C PTGIR CASP1 ST3GAL2 KLF9 STK17B PLBD1 NR1D2 VIM SELL C9orf72 WFS1 TANC1 RPS6KA2 MYLIP RYBP CTSS APBB2 IRF8 PRKCE N4BP3 PTGER2 GPR3 RRAS PKD2 MMP15 CBFA2T3 CD86 IRS2 RELL1 DBNDD2 IL18 CPQ GSTM5 SPARCL1 PIP4K2A RBM18 BRWD1 ULK2 RASSF8 RAB2B LTBP3 LYST DNAJB9 CYTH1 FAM13B	down	*
GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_UP	0.0078751	0.0349111	0.3807304	-0.2540000	-1.337006	170	RBMS2 ARRDC4 FYN NTM NUDT9 DYRK1A ABCB1 SLC44A2 PTS SLC25A17 IFI30 HSPB1 ABCG1 ANPEP TNS1 AKT3 CES1 LRP4 REST RBMS1 TLR4 PNRC1 UBE2B GCA HES1 HEXB NRROS NINJ1 CD80 UTRN OSBPL9 IRF8 GRB2 PTGER2 STX5 IDNK OGFRL1 IP6K1 CD164 KCNN2 BNIP3L SERTAD1 ESYT1 ACTB PSME4 ING2 STK4 CHCHD7 HEBP1 RNH1 SUGT1 EGR1	down	*
GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN	0.0102784	0.0424918	0.3807304	-0.2513420	-1.336312	180	ABHD5 GPR65 PID1 FOLR1 SLC39A8 IL1RN PPM1D TRA2B ENTPD1 HIPK3 TOR1AIP1 EFCAB14 MAP2K3 ITM2B CLK4 EPS15 PPP2R5A N4BP1 PIK3R5 BCLAF1 IKZF5 RSRC2 PIAS1 OASL OSTM1 DNAJA1 RPL9 IPO7 GLIPR1 GRB2 ZBTB24 RBM22 TCP1 RGS13 CGGBP1 ADNP2 ZFAND6 GALC SEMA4A FDFT1 FAM13B LPAR6 CYBA TNFSF8 CENPC SLC19A2 CYB5R2 MT1E YWHAB OTUB2 WDR41 DAPP1 WDR47 CAPZA1 STX16 DLD SETD2 ECHDC3 PLCB2 SRRM1 BTBD1 CBFB PLXNC1 PHIP SERPING1	down	*
GSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN	0.0105979	0.0431715	0.3807304	-0.2513027	-1.335088	179	FAM167A SWAP70 SNX10 SH2D3C NCF2 SYS1 LAMP1 DNASE1L3 CNST STARD4 RAPGEF4 IFI30 PDGFA ANKRD10 USP2 VASP STK17B SPAG9 ERP44 COTL1 RBMS1 ELMSAN1 TBC1D4 MAPRE2 SRF ASNSD1 CABLES1 HPGDS SH3BP5 MCM9 GLIPR1 GRASP BLOC1S6 PPTC7 ZNF521 TFEB ENPP6 VAMP4 KHDRBS1 TAGAP HACE1 UNC13D SESN1 SFT2D1 PARM1 ZBTB25 LTBP3 SPATA5L1 PUM1 PURB FCRL1 SDHAF2 CAPZB FBXW2 PTGS1 MICAL1	down	*
GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0107153	0.0435769	0.3807304	-0.2532374	-1.334860	172	SIGLEC11 MGAT3 ACP5 MCOLN1 RAMP2-AS1 CLDND1 EDEM1 TNFRSF8 SLC36A4 BZW1 PDE4D TFRC DIABLO GCHFR MAFG CXCL2 M6PR PLEKHB2 ADIPOR2 MAFF RBPJ RYBP VPS37A ARL5B VAT1 SH3BP5 NSMCE2 PPP1R15A HSPA13 REL SLC3A2 HIVEP2 SAV1 ZBTB1 GNAI1 CCDC68 SOD2 CRY1 NBEAL1 RIMKLB ICAM1 SETDB2 TPT1 TXNDC11 G3BP2 TRAF1 DNAJB9 ITCH CREG1	down	*
GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP	0.0089455	0.0383310	0.3807304	-0.2509878	-1.334612	185	ADPRH IL1RN PPP1R15B SERPINB9 SLAIN2 GPR4 CSRNP1 NOSTRIN PPM1K COQ10B REST DENND3 GRK5 FBXL3 CLIC4 NFKB1 PER1 PEF1 INSL6 SIAH1 PIAS1 GPBP1 MYO1C IL6 INPP5B NXF1 ETV3 STAT4 ELP5 ATP11A ARHGEF10 CCR7 PCGF5 GYPC GPR183 REL GTDC1 TNFRSF9 RNF24 OGFRL1 CLN3 TAGLN2 AGFG1 PNPLA2 ADPRM TGIF1 DYNC1LI1 PDCD1 ICAM1 SELPLG CHMP3 CDC42EP3 SPIB ARIH1 ISCU VSIG10 ACADM CYTH1 SAMSN1 LDLR MED31 HAT1 PSIP1 SPSB1	down	*
GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP	0.0093703	0.0398141	0.3807304	-0.2511894	-1.334264	177	FAM167A SLC12A6 FCN1 USP12 CYP27A1 SH2D3C CD44 NEDD9 CBL IGSF6 AVPI1 SEMA6D MAN2B1 HDC GPBP1L1 ADIPOR1 APOC1 SPNS3 BIRC2 FBXL3 MARVELD1 UBE2E2 ELAC1 PTGER3 B9D2 N4BP2L1 VAMP5 FOXN3 CREBRF GLIPR1 GPR183 CREB1 ENTPD4 CD7 PPTC7 MAPK8 PPP2CB CDC37L1 IL18 BLOC1S2 HIGD1C CCR9 METTL7A STK4 JMJD1C MTUS1 SAMSN1 ITCH FAM13B EIF4A2 BANK1 HTRA2 ZBTB16 CNR2 KBTBD11 KMT2E CD79B MAP4K2 DAPP1 RGS12 STX16 PAXBP1 DOCK5 AKAP13 ARHGAP30 KCTD18 ADAM19 PUM2 CRLF3 FAM107B RASSF5	down	*
GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN	0.0070670	0.0319097	0.4070179	-0.2506695	-1.334035	184	BMP2 DYRK1A MSLN VAPA CD9 OTUD4 SBDS CYB5A CLEC14A HSPB1 KLF6 GPBP1L1 EIF4E NR4A1 ADRB2 NFE2L2 CES1 CYP4V2 UBE2D3 BAG1 MTHFR ZYG11B MTMR6 CCL22 LIN7C TEF OXSR1 PTGIS AFF1 MAPRE2 AREG INMT SHOC2 EEA1 DDX5 SUCNR1 PSMD12 CCDC85A ZNF521 NUP153 OSGIN1 PDE12 ANKRD13A MBNL1 GTF2B TCTEX1D4 SLC34A2 EPN2 RAB5A CEBPD NFKBIA FAM126B RORA ZFAND2A NUP160 RNF13 HERPUD1 UBR2 CTSH FAM8A1 ALG2 YRDC UBE3A RMDN1 SERP1 DLD SLC23A2 ZFYVE21 ATF6 DOCK5 PTGS2 SEMA5A	down	*
GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN	0.0097891	0.0411498	0.3807304	-0.2522976	-1.332735	174	SWAP70 SECISBP2L OSBPL1A CPEB2 RCOR1 CD44 TMOD3 MYADM BMPR2 TACC1 LMNA EIF1 GM2A ZBTB8A GATA3 RGCC NPNT ZCCHC24 ST3GAL2 PXDC1 SOCS2 KLF7 VIM ADIPOR2 GNAQ PI4K2A NCOA1 MITF C20orf194 SNX29 COBLL1 LPCAT2 ATP13A3 SNX9 FOS TEX30 TSC22D1 LGALS3 NQO2 PLEKHO2 ITPRIPL2 SLC25A20 FBXO30 SOAT1 GLUL KIT DUSP7 EMC3 SPATA13 ATP6V0A1 EGR1 CCDC112	down	*
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP	0.0112391	0.0454037	0.3807304	-0.2508058	-1.332448	179	PTP4A2 DPYSL2 SIK1 TMOD3 CORO1C RTN3 QKI BMPR2 SPCS3 DNAJB14 TXNIP ANXA5 KLF10 HNRNPU BAG1 KPNA5 FLI1 HNRNPA3 BNIP2 YBX3 PSPN OSTF1 STK17B LAPTM5 MBD2 SEC31A ACTR2 CLN8 TMEM9B RBM39 JUN GLUD1 JUNB WTAP PIK3R1 PABPC4 IDS CXCL5 YWHAZ ADNP2 AGPS NAPG HNRNPD AZIN1 DUSP5 CSDE1 TOB1 NPTN ADAM10 IER5 G3BP2 RNF38 PAK2 DAZAP2 SFPQ DNAJA2 PPP1CB	down	*
GSE17721_LPS_VS_POLYIC_2H_BMDC_UP	0.0098938	0.0413729	0.3807304	-0.2521119	-1.331754	174	SASH1 CPEB2 FABP4 SLC16A4 CALCRL IDI1 NUDT9 NR3C1 DSCAML1 IL1RN RBM7 SLC25A17 MTF1 KLF6 SLC7A11 SLAIN2 TFEC EPM2AIP1 GMEB1 SLC12A4 KLF9 TMED5 EPM2A LY96 NFKB1 GPR85 DUSP1 WDR48 UFM1 TPP2 CLN3 ACSL1 KLB CD86 BRI3 TOB1 STK40 RGS2 RLF SLC31A1 EPHA2 TRAF1 NFKBIA SCUBE1 FDFT1 MCOLN2 DLST MMD MT2A PIM3 EGR1 SERPINE1 TNFSF8 CLOCK PRKCH FPR1 EFS BCL10 ADHFE1 IRF1 CSF3 PDPN SNTG2	down	*
GSE43957_UNTREATED_VS_NACL_TREATED_ANTI_CD3_CD28_STIM_CD4_TCELL_DN	0.0097891	0.0411498	0.3807304	-0.2506045	-1.331157	177	SEMA6B TSPAN4 DENND5A U2AF1 ADCY4 FYN EGR2 BACH1 MYD88 PAFAH1B2 SH2B3 LATS2 MAP3K8 HLX IL18R1 GRN TUBB6 FBXL5 ADARB1 IL10 ZFAND5 CLIC4 ERP44 SELP KPNA3 PROCR METAP1 SNAP23 RCAN1 PTGER4 FYTTD1 STX7 IRF8 SDHD CDK2AP2 STX5 CELF2 AGFG1 GRSF1 RRN3 DDX18 STRN SBF2 FEM1B MMP15 ORC2 ICAM1 SELPLG BNIP3L SEC63 PLGRKT TIMP3 MCOLN2 CYTH1 MT2A ZFAND2A RNH1 SPHK1 SUGT1	down	*
GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_DN	0.0120259	0.0478709	0.3807304	-0.2512779	-1.331149	175	IL1A OLR1 HCAR2 PLEKHF2 MKNK1 NEDD9 ZBTB2 NUMB RBM7 CLCF1 FOXJ3 TRAF6 ZYG11B RHOB MSR1 SDCBP PRKD3 STK17B VRK2 PLBD1 CTSD PAPSS1 PNRC1 ACTR3 ELK3 EVI2A MATK MAFF SACM1L NRROS SLC25A25 JUN ATP6V0B JUNB PTGER4 STX7 SERPINB6 HSD17B12 REL PRKACA DOCK8 NOP10 PPTC7 RIN2 PIK3C3 KAT2B PDE4B ETS2 CHURC1 TFPI IER5 NLRP3 DLST LDLR BMI1 PIM3 CHIC2 SVIL MAPK1 CLOCK	down	*
GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN	0.0103849	0.0426604	0.3807304	-0.2505674	-1.329761	176	GCSAML LPXN ADCY9 ARRDC4 IL1RN FUCA1 EPB41L3 RFTN1 HEG1 TACC1 ABCG2 BTG2 AHRR ZBTB21 CLN5 STOM TIPARP ZMIZ1 FUT7 CEBPA KIF26A SSH1 ELAC1 FCER1G WASF3 IL7R SPRYD7 MOB3A LACC1 AREG CABLES1 CD48 CTSZ ATP11A CCR7 SPRY4 SLC22A1 XYLT1 ZFAS1 C16orf72 DOK2 STON1 MR1 PITPNA LDLRAD4 SETDB2 SEMA4A PTCH1 KIT PDE4A	down	*
GSE43955_1H_VS_60H_ACT_CD4_TCELL_UP	0.0103849	0.0426604	0.3807304	-0.2504926	-1.329364	176	CD52 ADPRH CPEB2 ADCY4 TRPV2 FYN LY86 GPCPD1 ALAS1 BCL2A1 IL1RN ADAM17 LATS2 ITGA5 HIPK3 LCP1 IL18R1 TUBB6 IL10 SNAI1 PLAUR ZFAND5 CLIC4 DUSP1 CD300C SMNDC1 HLA-DQA1 DEGS1 AREG INO80C GABARAPL2 NXF1 CD48 C1QA AK1 RCAN1 PTGER4 FYTTD1 RBM22 AGFG1 FEM1B NAB1 TPMT KCNA3 DBNDD2 SELPLG RTN4 CDKN1C	down	*
GSE369_SOCS3_KO_VS_WT_LIVER_DN	0.0102079	0.0422935	0.3807304	-0.2500721	-1.328329	177	SECISBP2L THBD OTUD1 INPP5K ST3GAL6 KIAA1109 CALCRL S1PR1 MEF2A TGFBR2 CNST LACTB ENTPD1 CHMP1B HIPK3 CAV2 CAMTA1 TRAF6 SPTBN1 PPP1R13B AGO4 CCDC82 BIRC2 CDIP1 RRM2B EVI2A CPT1A FAM76B ARHGDIB AFF3 ZNF597 EPC2 CDK17 HIVEP2 ZFAND6 DCAF5 CD1D ZBTB1 DCK IRS2 HBP1 ATAD2B SIK3 PLGRKT JMJD1C ARPC5 CYTH1 PAIP2 RPL18A LPAR6 ABI1 SETX SDHAF2	down	*
GSE25087_TREG_VS_TCONV_ADULT_UP	0.0105220	0.0430421	0.3807304	-0.2498013	-1.326891	177	RAB11FIP1 RDX CLDND1 FYN FBXO3 RCHY1 DNAJC18 B3GNT5 RAP1A ANXA5 GATA3 SRGN CD58 TIPARP KDSR CASP1 SOCS2 SSH1 EPS15 GLB1 PHACTR2 IL2RB UTRN CCDC50 IDS FAM43A RALB CST7 LINC01006 SLC25A24 PIK3AP1 ZFAND6 PEA15 DUSP5 IRS2 SOD2 DOK2 GABARAPL1 KAT2B CCR6 IER5 CDC42EP3 TAB2 RBMS3 S100A4 SAMSN1 RORA IQGAP1 USP48 HERPUD1 CRTAP NR4A2 ATP1B1 FAM160B1 GOLGA8B RGS12 WDR47 CAPZA1 ATP2B4 SKAP2 IRF4 ZNF80 GALM ADCY3 CBLL1 TNFRSF1B F2RL2	down	*
GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_DN	0.0117556	0.0470611	0.3807304	-0.2525401	-1.325875	167	LRRC8C FABP4 LMO2 MYD88 NUDT9 KCNAB1 RBM7 ANXA1 CSRP1 KLF6 PCDH12 SERPINB9 MCL1 CST3 TIPARP CWC22 SDCBP ATP6V1D RMDN3 P2RY2 NR1D2 C9orf72 WDR48 EVI2A WFS1 EFR3A MAPRE2 HCK USP25 MOB4 MYLIP INO80C APPL1 ETV3 DNAJA1 GRB2 FRYL MORC3 OGFRL1 CCR4 PIM1 LGALS3 EXOC1 ELF5 ADAMTS4 RTN4 TAB2 ARIH1 ARL14EP PSME4 STK4 NFKBIA B3GNT2	down	*
GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP	0.0117556	0.0470611	0.3807304	-0.2513201	-1.324754	172	PPARG ZC3H12C LRRC8C DCSTAMP PTPRE CLDND1 PLEKHA1 FXYD2 IL1RL1 PFDN1 C1orf21 ITGA5 KLF6 SLC7A11 SPNS3 PLAUR GCHFR NES PRKD3 PDE8A CDKN1A ITGAX CCL4 SS18L2 PER1 SMAD7 SPRYD7 ANXA3 CNNM2 APBB2 FAM43A OSM MALT1 LPCAT2 RUNX3 FLNC SMPDL3B TIMP2 FEM1B	down	*
GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0125235	0.0494446	0.3807304	-0.2491140	-1.324466	180	FAM167A OTUD1 CALCRL MANBA GIMAP6 GGA2 LACTB ASAP1 CHMP1B MAP3K8 FOXP1 ABHD6 EVI2B ARRB1 SPNS3 SCAF4 SPAG9 SEC24B SSH1 HOPX HPSE OXSR1 CNOT6L CNRIP1 NRROS USP25 MYO1C PDIK1L RAB31 SLC14A1 RABGAP1 EPC1 PTGER4 CREB1 LETM2 SNX9 MBP KCTD10 TEC MCUR1 CD86 SMAD2 BMP2K MIER1 SERTAD1 ZBTB25 SOAT1 COMMD8 GLUL GPR171 PAIP2 GIMAP4	down	*
GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_UP	0.0117556	0.0470611	0.3807304	-0.2511892	-1.324064	172	SLPI LTA4H MIR22HG LIPA INSIG1 ELF2 APIP RBM7 PTS CSRP1 NLK BFAR BTG3 FBXL5 KDSR GCHFR ST3GAL2 MAP1LC3B IRAK2 CLK4 DUSP1 PPP2R5C NRBF2 COPS4 PRCP CD8B PRKRA MED28 STAT4 MED30 MN1 OSBPL9 RHOG CGGBP1 WDR7 NDUFV2 MSMO1 SAV1 VAMP4 FPR2 PDCD1 DOK2 GABARAPL1 GEM FBXO25 PLGRKT RBM48 PAIP2 SAMSN1 SLC22A3 FAM13B EMC3 CNOT8 HAT1 GPN2 CHIC2 DUSP6 ENDOD1 HIPK1	down	*
GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_UP	0.0121717	0.0482509	0.3807304	-0.2519091	-1.322562	167	SLC31A2 OLR1 SLC39A8 SLC11A1 LTBP4 WNT2B CYB5A LITAF HLX TFRC TXN SLC5A2 CASP5 MAP2K3 EPOR PARVB TJP1 CCL3 NFKB1 SELL ARC INHBA N4BP1 TBC1D4 BTG1 NINJ1 EMP3 CAPN11 GSTO1 CD83 SELENBP1 GRB2 RALB CST7 CELF2 FOXO3 PRKCG EHD1 SFTPC DUSP5 KCNA3 SOD2 NQO2 ETS2 GEM NBN TFPI ALDH1B1 CXCR4 TRAF1 FAM13C DOCK4 MT2A GREM1 CSF2RB FAM131B FKBP1B	down	*
GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN	0.0114831	0.0461977	0.3807304	-0.2472443	-1.322350	183	BAG4 S1PR1 BCL2A1 ATF7IP2 ABCB1 UBL3 LITAF KLF10 CLN5 DACH1 SPRY2 ZFYVE16 PDGFA FBXL5 KDSR TIMM10B FOXO1 LIN7C COQ10B PRKD3 GAPVD1 LY96 ABCC4 MGAT4A PER2 CTBS SMAD7 N4BP2L1 TDRD7 HGSNAT ARHGAP17 MYLIP MTMR14 GPR183 DENND4A CDK17 PTP4A1 XYLT1 IFNAR1 ATXN1 PDLIM5 EXOC2 SLC31A1 GIMAP5 CREBBP NPAT CYTH1 C21orf91 GIMAP4 RSU1	down	*
GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN	0.0098165	0.0411902	0.3807304	-0.2486841	-1.317483	186	NLRC4 ACP5 CXCL16 KLF13 HHEX PTP4A2 ENG TMEM170B LYL1 SH2D3C CTDSP1 FRAT1 TACC1 IFI30 GRN MPEG1 TMBIM1 LAPTM5 COTL1 EVI2A STK24 SNX3 ARL6IP5 HECA RAB31 DDX17 TYROBP RHOG STX7 RAB8A RPS6KA1 VMO1 RUNX3 TIMP2 TFEB ZBTB11-AS1 DOK2 BRI3 THAP11 PLEKHO2 MR1 JUND GLTP CALHM2 ELOVL1 CXCR4 IFFO1 GLUL DUSP7	down	*
GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN	0.0094192	0.0399740	0.3807304	-0.2501437	-1.316707	170	POLR3H LIPA INSIG1 HSD17B11 TGFBR3 NDUFAF7 COX18 PAG1 CRK SYNPO FOXO1 ID3 C16orf54 AFF3 SNX3 TMEM9B ETF1 WASF2 PNO1 INPP5B SEC14L1 SH3BP5 ZFP91 NXPE3 CCR7 YWHAZ KLF2 AKIRIN2 DCK PDLIM1 NAB1 ZC3H12D CNOT7 PDCD1 DECR1 KANSL2 ABL2 BLOC1S2 TEX10 PIP4K2A KPNA4 STK4 SKI CYTH1 MMD FAM13B C1orf52 SMAD4 EHD3 GRPEL1 ARHGEF18 EGR1 CDON CLIP1 SLC26A11 CCNT2 MUL1 CUL2 STARD5 MAP3K1	down	*
GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP	0.0101398	0.0420791	0.3807304	-0.2484964	-1.308036	170	EPAS1 ST8SIA6 ADTRP GPR65 PID1 OTUD1 ST3GAL6 ELF2 C8orf58 ABCB1 ERG ZBTB4 ATP2B1 METTL23 BEST1 FOXP1 KLF6 PRSS12 PAG1 BTG3 CYP4V2 TLE4 BIRC2 PIP5K1B RRM2B PRKD3 PDE8A NR1D2 IL7R PIK3R5 CRIM1 BTG1 CREBRF SGK1 NDNF ATXN1L PIK3R1 DDX5	down	*
GSE41867_DAY6_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP	0.0121037	0.0480207	0.3807304	-0.2466963	-1.298561	170	SLPI MYO7B SOWAHC LRRC8C CAT IBA57 RFTN1 GINM1 AVPI1 CNST DNAJC3 RAPGEF4 RAP1A RAB33B PBX3 TRAF6 CD93 ZYG11B GPM6A USP2 SPAG9 PMM1 MBD2 WFS1 TBC1D4 COPS4 MAPRE2 ZNF330 AQP3 CD48 MSRB3 GAS2L3 GRSF1 MFSD10 ZNF521 SAV1 KHDRBS1 GALC ATXN1	down	*
GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP	0.0121037	0.0480207	0.3807304	-0.2466940	-1.298549	170	KLF13 ATXN3 RAPGEF2 MIR22HG RTN3 MSRA ALAS1 PPM1D ACER3 TMX4 CNTD1 LAMTOR3 PTPN12 CASP1 FAM49B VIM PPP2R5A C16orf54 CTSS INPP5B APPL1 TYROBP ATP13A3 TRAK2 ZCCHC9 GAS2L3 MOB1A RRAS AGPS NR2C1 YTHDF2 ATP6V1A IFNAR1 EXOC2 CDC42EP3 TXNDC11 TMEM109 NHLRC3 RNF38 DUSP7 DAZAP2 TLK1 NCF1 SLC38A2 XPO7 EXOC6 RCSD1 SCAF11 USP45 JARID2 AKAP13 METRNL KCTD18 FBXO33 EXTL2	down	*
GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN	0.0121037	0.0480207	0.3807304	-0.2466907	-1.298532	170	AKAP5 PPARG PTPRE ARRDC4 SLC10A1 GFOD1 GTF2E2 AQP9 FLVCR2 NCF2 CD1C GALNT18 DDO DNASE1L3 PLXNA2 ABCG2 LCP1 PER2 CDKN1A VIM CCL4 MATK WFS1 CD300LB CLIC5 FLT1 BCAR3 EBF2 JUN ETS1 CD83 LYRM1 PTGER2 AKIRIN2 NIPA2 CTNNAL1 MCUR1 PITPNA FKBP1A CES3 PARM1 ACTB TRAF1 TIMP3 CD1E CHCHD7 ANXA11 EHD4	down	*

All signatures Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER	0.0000000	0.0000000	1.3951871	0.7005670	3.067254	127	TRIP13 FOXM1 HELLS KIF20A HJURP MCM10 FANCI BUB1B NEK2 CCNB1 CENPF POLQ PBK KIF18B NDC80 BRCA1 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 DNMT3B ASPM STIL PLK1 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 PRC1 CCNF DTL GINS4 ZWINT SPDL1 MELK HMMR KIF23 CEP55 PAQR4 MKI67 KIF15 PAFAH1B3 BUB1 TOP2A AURKA POLA2 KIF2C RRM2 KIF11 CHAF1B LMNB1 CHEK1 MAD2L1 RAD51AP1 NUSAP1 ASF1B CDK1 BIRC5 GMNN E2F1 NCAPG DNA2 FEN1 EZH2 SPAG5 DPP3 DLGAP5 TACC3 MAPK13 TK1 DTYMK ANP32E KIF20B	up	***
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.0000000	0.0000000	1.3188888	-0.5693712	-3.058777	189	CXCL3 IL1A OLR1 DENND5A IL1B PTPRE BMP2 SIK1 EGR2 CD44 CCRL2 FOSL1 BCL2A1 TRIB1 IL23A IER2 CCNL1 ATP2B1 CLCF1 HBEGF EIF1 BTG2 MAP3K8 LITAF KLF10 KLF6 PTX3 NR4A1 NFE2L2 BTG3 MCL1 TIPARP RHOB MAP2K3 STAT5A BIRC2 KLF4 PLAUR KLF9 DRAM1 NFKB1 CDKN1A CXCL2 ATF3 ID2 CCL4 PNRC1 PER1 DUSP1 PLEK INHBA IL7R HES1 MAFF SNN BTG1 NINJ1 CD80 AREG IL6 SGK1 SOCS3 SERPINB8 JUN JUNB RCAN1 PPP1R15A PTGER4 ACKR3 CD83 GPR183 REL TNFRSF9 GFPT2 FOS KLF2 FOSB EHD1 TGIF1 TSC22D1 DUSP5 IRS2 SOD2 KYNU PDE4B ETS2 CCL20 GEM ICAM1 IL18 PDLIM5 TNFAIP8 IER5 CEBPD RIPK2 TRAF1 NFKBIA EDN1 TNFSF9 LDLR SPHK1 CSF2 SPSB1 EGR1 SERPINE1 FJX1 NR4A2 ZFP36 YRDC DNAJB4 CD69	down	***
PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN	0.0000000	0.0000000	1.1866510	-0.6058907	-3.050364	124	PTP4A2 SIK1 THAP2 YPEL5 TMX4 CCNL1 CNST TRA2B SBDS PPP1R15B EIF1 EIF5 MAP3K8 CSGALNACT2 KLF10 FOXP1 KLF6 EIF4E GATA3 RGCC CLK1 PDE4D MCL1 TIPARP CSRNP1 MOAP1 SRSF5 KLF4 ZFAND5 STK17B MGAT4A ID2 PER1 RNF139 CCDC59 IKZF5 CNOT6L RSRC2 BTG1 MYLIP AREG CREM HECA JUN EPC1 PPP1R15A PTGER4 IFRD1 PNPLA8 MPZL3 IDS ZBTB24 REL PELI1 PTP4A1 FOSB ING3 CD6 IRS2 C16orf72 GABARAPL1 TOB1 RGS2 HAUS3 AMD1 JUND IER5 SIK3 MEX3C G3BP2 JMJD1C B3GNT2 ZFAND2A PMAIP1 NR4A2 HIPK1 ZFP36 CD69 TSC22D2 SETD2 NR4A3 ZNF331 DUSP2 FBXO33 SON	down	***
SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP	0.0000000	0.0000000	1.4025887	0.6909568	3.041410	132	TRIP13 FOXM1 KIF20A HJURP CDC45 PARPBP MCM10 TROAP BUB1B NEK2 CCNB1 CENPF TIMELESS POLQ KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 GMPS ASPM STIL PLK1 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 TPX2 CCNB2 MCM4 MCM2 RAD54B CDC25A MYBL2 PRC1 MIS18A SHMT2 XPOT ZWINT NME1 MELK HMMR EXO1 NUDT1 CEP55 MKI67 KIF15 MRPL15 BUB1 TOP2A CCT5 AURKA KIF2C RRM2 KIF11 MCM3 LMNB1 CHEK1 DNAJC9 MAD2L1 DSCC1 PKMYT1 BLM NCAPG2 NUSAP1 CDK1 BIRC5 E2F1 NCAPG FEN1 EZH2 SPAG5 QPRT RNASEH2A DLGAP5 TACC3	up	***
GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.2462328	-0.5757645	-3.021867	165	CXCL3 EREG IL1A DENND5A USP12 ADTRP IL1B RAPGEF2 OTUD1 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 PSMD5 IL23A STARD4 ATP2B1 PTS HECW2 PPP1R15B TNIP3 MAP3K8 PTX3 ADRB2 NFE2L2 TXN CASP5 EIF1B IL10 CSRNP1 STAT5A DUSP3 PLAUR DRAM1 NFKB1 CXCL2 ID2 CCL4 TAF9 DUSP1 PLEK INHBA TP53BP2 MAFF RASGEF1B KANK1 AREG RYBP NSMAF SOCS3 SERPINB8 JUN ARL5B STAT4 PLK3 PPP1R15A ELOVL7 CCR7 CD83 OSM REL CXCL5 GPRC5A DENND4A ACSL1 SNX9 PELI1 PTP4A1 HIVEP2 PIK3AP1 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 ETS2 CCL20 GEM ICAM1 LDLRAD4 IL18 ABL2 MIR155HG RIPK2 NLRP3 RND1 MAP3K4 HNRNPC NFKBIA EDN1 FNIP2 B3GNT2 TNFSF9 PMAIP1 PIM3 NAF1 EGR1 FJX1 DCUN1D3 MSANTD3 YRDC DNAJB4	down	***
GNF2_CASP1	0.0000000	0.0000000	1.0476265	-0.6159634	-2.983644	94	FCN1 PECAM1 MNDA HSD17B11 CD44 SAMHD1 MYD88 STX11 NCF2 IGSF6 PILRA LILRB3 FGR IER2 DPEP2 CD33 NAAA CSGALNACT2 MCL1 FBXL5 EVI2B PPT1 CASP1 BST1 CPVL PLBD1 COTL1 SELL CD302 FCER1G DUSP1 EVI2A FKBP15 CMTM6 HCK CTSS HK3 TYROBP JUNB RHOG IFNGR1 GMFG CD1D CD86 CCR1 RGS2 ARRB2 ACAP2 S100A4 THEMIS2 DAZAP2 IQGAP1	down	***
GNF2_HCK	0.0000000	0.0000000	1.0073180	-0.6315769	-2.937390	80	FCN1 PECAM1 MNDA HSD17B11 C5AR1 STX11 NCF2 FRAT1 IGSF6 PILRA LILRB3 FGR DPEP2 SLC7A7 CLEC7A CD93 SPI1 MCL1 FBXL5 EVI2B PPT1 SDCBP CASP1 BST1 CPVL PLBD1 LY96 COTL1 ITGAX CD302 FCER1G EVI2A CMTM6 HCK CTSS HK3 TYROBP TREM1 RHOG IFNGR1	down	***
GNF2_MCL1	0.0000000	0.0000000	0.9101197	-0.6973667	-2.931445	47	RAB11FIP1 PECAM1 MNDA PTPRE HSD17B11 SAMHD1 MYD88 STX11 NCF2 IGSF6 IER2 DPEP2 CSGALNACT2 MCL1 FBXL5 EVI2B PPT1 CASP1 SELL CD302 CMTM6 HCK CTSS JUNB IFNGR1 CCR1 RGS2 ARRB2 ACAP2 S100A4 THEMIS2 DAZAP2	down	***
GSE29618_BCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.2295041	-0.5520681	-2.930555	178	SLC31A2 HMOX1 DENND5A PECAM1 LTA4H FBP1 DPYSL2 MIR22HG PID1 HSD17B11 CD44 RTN3 MYD88 C5AR1 EPB41L3 TRIB1 PILRA LILRB3 RHOA MCTP1 HBEGF CD33 SLC7A7 BEST1 IFI30 PICALM ANXA5 PTX3 STOM CD93 TCF7L2 ATP6V1B2 FBXL5 ZMIZ1 SDCBP KIAA0513 CASP1 BST1 PTAFR KLF4 PLAUR ITM2B ZFAND5 CEBPA TPP1 COTL1 CXCL2 VIM HPSE TLR4 CAPZA2 PLEK GNAQ VAMP3 CTSS RAB31 TREM1 RHOG IFNGR1 GSTO1 GMFG ACSL1 ALDH3B1 RIN2 PEA15 ATP6V1A TSPAN14 ATP6V0C GNG5 SOD2 CCR1 RXRA SELPLG ARPC2 FKBP1A RTN1 RTN4 CDC42EP3 CEBPD TIAM1 NLRP3 UBE2D1 ULK2 DAPK1 CREG1 GIMAP4 WDFY3 GRPEL1 PPP2R3C CHP1 DUSP6 SVIL AOAH FTL NDFIP1 QSOX1	down	***
GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.1778933	-0.5574899	-2.920555	163	CXCL3 IL1A DENND5A USP12 ADTRP IL1B LRRC8C RAPGEF2 OTUD1 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 OTUD4 IL23A STARD4 ATP2B1 HECW2 PPP1R15B BTG2 TNIP3 MAP3K8 PTX3 ZNF697 ADRB2 TXN CASP5 EIF1B IL10 CSRNP1 STAT5A PLAUR DRAM1 NFKB1 CXCL2 ID2 CCL4 TAF9 DUSP1 PLEK INHBA TP53BP2 MAFF RASGEF1B KANK1 AREG IL6 RYBP SOCS3 SERPINB8 JUN ARL5B PLK3 PPP1R15A ELOVL7 CCR7 CD83 DDX5 REL DENND4A ACSL1 SNX9 PELI1 PTP4A1 NIPAL4 PIK3AP1 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 ETS2 CCL20 GEM ICAM1 LDLRAD4 IL18 ABL2 MIR155HG RIPK2 NLRP3 RND1 MAP3K4 HNRNPC NFKBIA EDN1 FNIP2 B3GNT2 PMAIP1 PIM3 NAF1 EGR1 FJX1 DCUN1D3 MSANTD3 YRDC DNAJB4	down	***
GNF2_CCNA2	0.0000000	0.0000000	1.0768682	0.7378206	2.919372	63	FOXM1 KIF20A HJURP FANCI BUB1B CENPF KIF18B NDC80 TTK RACGAP1 E2F8 KIF14 ASPM PLK1 CDCA8 AURKB CENPA ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 NCAPD2 ZWINT MELK HMMR MKI67 TOP2A AURKA MCM7 RRM2 KIF11 MCM3 RAD51AP1 CKS1B NUSAP1 ASF1B CDK1 BIRC5 GMNN NCAPG FEN1 EZH2	up	***
GSE29618_MONOCYTE_VS_MDC_UP	0.0000000	0.0000000	1.2210538	-0.5490198	-2.914374	178	SIRPB1 SLC31A2 HMOX1 ABHD5 FCN1 LTA4H CYP27A1 MIR22HG EGR2 CD44 BACH1 RTN3 C5AR1 MKNK1 MARCO BCL2A1 NCF2 LAMP1 SLC11A1 PILRA LILRB3 FGR CD36 PLA2G7 SLC7A7 BEST1 ASAH1 EIF1 BTG2 IFI30 ADIPOR1 CD93 TCF7L2 FBXL5 CFD SDCBP KIAA0513 BST1 ITM2B DRAM1 KLF7 CTSD RIT1 RBMS1 CXCL2 HPSE TLR4 FCER1G EVI2A MBD2 LIN7A NINJ1 HCAR3 FRY CTSS PGD MAP4K4 TYROBP TREM1 GMFG PTGER2 ACSL1 SPRY4 PELI1 PNPLA2 TNFSF13 RIN2 BIN2 CR1 FXYD6 IRS2 ATXN1 APLP2 SOD2 CCR1 RXRA BNIP3L CDC42EP3 TIAM1 GIMAP5 NLRP3 UBE2D1 IFFO1 SCPEP1 S100A4 GLUL NFKBIA MARC1 LDLR CREG1 DMXL2 EGR1 DUSP6 AOAH FTL S100A8 FPR1	down	***
GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.1953445	-0.5533809	-2.897423	166	CXCL3 EREG IL1A DENND5A USP12 ADTRP IL1B RAPGEF2 OTUD1 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 PSMD5 IL23A STARD4 CLCF1 PTS HECW2 PPP1R15B BTG2 TNIP3 MAP3K8 PTX3 NR4A1 RGCC NFE2L2 ARHGEF2 BTG3 TFRC TXN CASP5 EIF1B IL10 CSRNP1 STAT5A PLAUR NFKB1 CXCL2 ID2 CCL4 DUSP1 CCDC59 PLEK INHBA HES1 TP53BP2 MAFF AREG IL6 RYBP SOCS3 SERPINB8 JUN ARL5B PLK3 PPP1R15A WTAP PTGER4 CCR7 CD83 DDX5 REL CXCL5 DENND4A ACSL1 PELI1 PTP4A1 HIVEP2 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 PDE4B ETS2 CCL20 ICAM1 IL18 MIR155HG NBN LMOD1 RIPK2 NLRP3 UBE2D1 RND1 MAP3K4 HNRNPC NFKBIA EDN1 B3GNT2 PIM3 NAF1 EGR1 NR4A2 DCUN1D3 MSANTD3 YRDC DNAJB4	down	***
LEE_EARLY_T_LYMPHOCYTE_UP	0.0000000	0.0000000	1.1778933	0.6932281	2.889523	90	KIF20A MCM10 FANCI BUB1B NEK2 CCNB1 UBE2T PBK KIF18B NDC80 TTK GINS1 CDCA2 E2F8 KIF14 ASPM CEP70 NUF2 CENPA PTTG1 TFDP2 CCNB2 UHRF1 MCM4 MCM2 TYMS CDC25A PRC1 DTL MELK HMMR CEP55 MKI67 KIF15 BUB1 TOP2A AURKA KIF2C E2F2 CENPW RRM2 KIF11 RAD51AP1 DSCC1 TSHR PON1 NUSAP1 CDK1 TNFRSF21 BIRC5 NCAPG NEIL3 DIAPH3 RAPGEF5 DLGAP5	up	***
GSE22886_NAIVE_TCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.1953445	-0.5428203	-2.881200	180	SLC31A2 ABHD5 MNDA FBP1 SNX10 PTPRE COQ2 CCDC88A BACH1 CORO1C FLVCR2 SLC15A3 TBC1D2 MANBA NCF2 SLC11A1 FAM49A IGSF6 PILRA LILRB3 FGR CD36 SH2B3 MCTP1 CD33 SLC7A7 ASAH1 CLEC7A IFI30 PICALM SIRPA CD93 GRN ATP6V1B2 ZMIZ1 DUSP3 SDCBP CASP1 PTAFR CPVL ZFAND5 STX3 TPP1 PLBD1 LY96 ATG7 LAPTM5 KCNMB1 GCA FKBP15 GLB1 HEXB VAMP3 PGD MTMR14 KCTD12 HK3 ATP6V0B IFNGR1 CSTA TBC1D12 STX7 TNFRSF10B ACSL1 ATP6V0D1 RHOQ TNFSF13 RIN2 TIMP2 PEA15 ATP6V1A APLP2 LGALS3 EXOC1 CCR1 STX12 RXRA PDLIM5 RTN1 SEMA4A CDC42EP3 CEBPD NLRP3 UBE2D1 SCPEP1 DAPK1 GLUL SIGLEC9 CREG1 FEZ2 DMXL2 CSF2RB CTSH DUSP6 FTL FPR1 PTGS1	down	***
DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP	0.0000000	0.0000000	1.6024311	0.6041507	2.877812	288	TRIP13 FOXM1 HELLS KCNK5 CDC45 TICRR MCM10 FANCI C1QTNF6 DEPTOR TROAP BUB1B NUP107 XYLB CCDC34 TIMELESS POLQ UBE2T C21orf58 PBK TTF2 SLC2A1 BRCA1 DEPDC1B CDCA7 TTK GINS1 CDCA2 RACGAP1 IQGAP3 E2F8 GTSE1 SLC27A2 ANLN TRAIP POLE ASPM STIL PLK1 AURKB PTTG1 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 STC2 RBBP8 H19 UHRF1 MCM4 MCM2 RAD54B TYMS MYBL2 CA12 PRC1 XRCC2 DTL GLB1L2 MCM8 MIS18A NCAPD2 ZWINT CDT1 SPDL1 NME1 WDR62 NR2C2AP MELK NOS1AP EXO1 KIF23 CEP55 CHAF1A PAQR4 MKI67 KNTC1 BUB1 FANCA TOP2A CENPL AURKA POLA2 POLD2 KIF2C MCM7 E2F2 CLSPN MPHOSPH9 RRM2 MMS22L CDCA5 WDHD1 RAD54L KIF11 FANCD2 MCM3 CHAF1B LMNB1 LIG1 BRI3BP SLC9A3R1 CHEK1 CENPO SPC24 DSCC1 PKMYT1 BRIP1 RAD18 BLM TST SKP2 INCENP KNSTRN NCAPG2 NUSAP1 CBX5 ASF1B CDK1 POLE2 EXOSC2 CENPJ BIRC5 RAPGEFL1 GMNN E2F1 UNG NCAPG L2HGDH DNA2 FEN1 SPAG5 TMEM120B RECQL4 RNASEH2A SNRNP25 MYO19 DNMT1 FANCG DLGAP5 SLC26A2 TACC3 TK1 CHTF18 ESCO2 SLC22A5 GINS2 MAP6D1 POLD1 NUP85 ATAD5 DHTKD1 CENPM WDR34 MCM6 MCM5 TFAP4 GINS3 LRIG1 EXOSC5 HAUS4 LSM4 CHRNA5 ATAD2 CEP85 SUV39H2 CCNA2 ADCY1 PRIM1 PRR11 SHCBP1 RFC5 RAD51 ZWILCH ARHGAP11A WDR76 CELSR2 SMC2 TONSL	up	***
GSE29618_MONOCYTE_VS_PDC_UP	0.0000000	0.0000000	1.1690700	-0.5414862	-2.874668	174	SLC31A2 HMOX1 PTP4A2 CD44 LY86 C5AR1 P2RY13 MARCO BCL2A1 NCF2 IL1RN EPB41L3 TRIB1 PILRA LILRB3 FGR IER2 ANXA1 DPEP2 PLA2G7 HBEGF CD33 SLC7A7 BEST1 ASAH1 ENTPD1 CLEC7A CSRP1 SIRPA CD93 SPI1 TCF7L2 CD58 RHOB FBXL5 EVI2B TLE4 SDCBP CASP1 BST1 TNFSF12 YBX3 ITM2B KLF11 CEBPA PLBD1 ITPK1 ITGAX PTPRC HPSE TLR4 MBD2 SLC6A6 LIN7A ARHGDIB HCK HCAR3 CTSS SEC14L1 RAB31 TYROBP TREM1 GMFG ACSL1 PELI1 ALDH3B1 RIN2 TIMP2 GSAP CD1D TSPAN14 CD86 IRS2 APLP2 SOD2 LGALS3 TSPO RXRA BNIP3L CDC42EP3 NLRP3 UBE2D1 MEGF9 SCPEP1 S100A4 LYST HEBP1 CREG1 WDFY3	down	***
GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.1953445	-0.5402401	-2.867768	178	SLC31A2 HMOX1 ABHD5 FCN1 MNDA FBP1 PTPRE COQ2 BACH1 CORO1C FLVCR2 C5AR1 SLC15A3 TBC1D2 MANBA NCF2 SLC11A1 FAM49A IGSF6 PILRA LILRB3 FGR CD36 MCTP1 CD33 SLC7A7 ASAH1 CLEC7A IFI30 SIRPA CD93 GRN CST3 ZMIZ1 DUSP3 SDCBP PTAFR KLF4 CPVL PLBD1 LY96 ATG7 LAPTM5 KCNMB1 FCER1G GCA HEXB HCK VAMP3 CTSS PGD MTMR14 RAB31 KCTD12 TYROBP IFNGR1 CSTA TBC1D12 IRF8 TNFRSF10B ACSL1 PLCG2 TNFSF13 RIN2 TIMP2 ATP6V1A APLP2 LGALS3 EXOC1 CCR1 ADPGK STX12 CLCN6 RXRA RTN1 SEMA4A CDC42EP3 CEBPD DAPK1 GLUL SIGLEC9 CREG1 FEZ2 LYZ DMXL2 CSF2RB CTSH DUSP6 FTL S100A8 FPR1 PTGS1 QSOX1 PPFIA1 MFSD1 CAPZA1	down	***
MODULE_54	0.0000000	0.0000000	1.4390257	0.6111485	2.862933	224	TRIP13 PLAT DDX11 FOXM1 HJURP CDC45 ELOVL6 TROAP BUB1B NEK2 CCNB1 CENPF TIMELESS POLQ UBE2T PSPH PBK NDC80 DEPDC1 DEPDC1B CDCA7 TTK GINS1 CDK4 E2F8 KIF14 ANLN ASPM PLK1 NUF2 AURKB CENPA PTTG1 ECT2 CDC6 TPX2 CCNB2 CMYA5 MCM4 MCM2 TYMS MYBL2 ORC1 CCNF HBB CCT6A SRPK1 NCAPD2 ZWINT SCG5 NME1 RANBP1 ITGA2 MELK HMMR NUDT1 KIF23 CEP55 CHAF1A MKI67 KNTC1 RHNO1 BUB1 TOP2A CCT5 AURKA KIF2C MCM7 RRM2 CDCA5 RAD54L KIF11 GPSM2 MCM3 CHAF1B LMNB1 CDC25C AIMP2 TOPBP1 CHEK1 MAD2L1 AHCY PFKP PKMYT1 BLM PSRC1 KNSTRN CKS1B CDKN2C NUSAP1 TMEM106C MB ASF1B CDK1 POLE2 BIRC5 GMNN E2F1 UNG NEIL3 FEN1 SPAG5 SNRPE RECQL4 LAPTM4B TRIM24 DLGAP5 AMPH TACC3 LMNB2 MAPK13 DTYMK GINS2 ANP32E AGPAT5 POLD1 CDC7 CDC20 KIAA0100 HMGA1 MCM6 CKAP2 MCM5 LRRC17 RCC1 NT5DC2 GAD1 ATAD2 MSH2 CCNA2 PRIM1 CDH1 PRR11 SHCBP1 RFC5 RAD51 ZWILCH ARHGAP11A	up	***
GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	1.1778933	-0.5353948	-2.843968	179	SLC31A2 ABHD5 FCN1 MNDA FBP1 SNX10 PTPRE COQ2 CORO1C FLVCR2 C5AR1 SLC15A3 TBC1D2 MANBA NCF2 SLC11A1 FAM49A IGSF6 PILRA LILRB3 FGR CD36 SH2B3 SLC7A7 ASAH1 CLEC7A IFI30 KLF10 SIRPA CD93 GRN SPI1 ZMIZ1 DUSP3 SDCBP CASP1 YBX3 KLF4 TPP1 PLBD1 LY96 KCNMB1 FCER1G GCA FKBP15 GLB1 HEXB HCK VAMP3 CTSS PGD MTMR14 RAB31 KCTD12 HK3 ATP6V0B IFNGR1 CSTA TBC1D12 STX7 IRF8 TNFRSF10B PLCG2 FOS ATP6V0D1 TNFSF13 RIN2 TIMP2 ATP6V1A LGALS3 EXOC1 CCR1 STX12 NPTN CLCN6 RXRA PDLIM5 SEMA4A CDC42EP3 CEBPD UBE2D1 MEGF9 SCPEP1 DAPK1 GLUL GLRX2 SIGLEC9 CREG1 FEZ2 LYZ DMXL2 CSF2RB CTSH DUSP6 FTL S100A8 FPR1 PTGS1 PPFIA1 MFSD1 CAPZA1	down	***
GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP	0.0000000	0.0000000	1.1778933	-0.5351173	-2.842494	179	SIRPB1 SASH1 HMOX1 FCN1 MCOLN1 ASGR1 LTA4H CYP27A1 CD44 RTN3 C5AR1 MKNK1 MARCO MANBA NCF2 GIMAP6 FUCA1 LAMP1 SLC11A1 PILRA RHOA CD36 DPEP2 PLA2G7 SLC7A7 BEST1 ASAH1 NAAA CLEC7A BTG2 SERINC1 PTX3 LAIR1 TCF7L2 ATP6V1B2 FBXL5 SDCBP KIAA0513 BST1 ITM2B DRAM1 GRK5 KLF7 PLBD1 CTSD TMBIM1 RBMS1 CXCL2 ARAP3 DUSP1 EVI2A MBD2 CLIP4 LIN7A NINJ1 HCAR3 VAMP3 FRY CTSS PGD UTRN TREM1 SNX2 PTGER2 ACSL1 AGFG1 PELI1 KLF2 RIN2 BIN2 CR1 FXYD6 TSPAN14 ATXN1 APLP2 SOD2 LGALS3 ICAM1 BNIP3L CDC42EP3 GIMAP5 UBE2D1 IFFO1 SCPEP1 GLUL NFKBIA MARC1 THEMIS2 CREG1 GIMAP4 DMXL2 EGR1 DUSP6 LHFPL2 FTL S100A8	down	***
GNF2_BUB1B	0.0000000	0.0000000	0.9759947	0.7501970	2.817135	49	HELLS KIF20A HJURP FANCI BUB1B NDC80 TTK GINS1 RACGAP1 KIF14 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS NCAPD2 ZWINT MELK HMMR CEP55 BUB1 TOP2A AURKA RRM2 KIF11 MCM3 LMNB1 ASF1B GMNN NUP205 SPAG5 PA2G4	up	***
GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP	0.0000000	0.0000000	1.1512205	-0.5285625	-2.810356	175	PHACTR1 USP12 PPARG DCSTAMP MIR22HG PTPRE CLDND1 THBD RRN3P2 LPL EGR2 GFOD1 ST3GAL6 FOSL1 GPCPD1 TBC1D7 TBC1D2 NR3C1 TRIB1 CNST RRAGC B3GNT5 HBEGF SGMS2 HECW2 LINC01010 ZBTB21 KLF10 NR4A1 RGCC SPRY2 CRTAM ZFYVE16 TFRC TXN TMEM38B ATP6V1B2 CSRNP1 MOAP1 DUSP3 ADO ACSL3 PLAUR COQ10B TNFSF15 STX3 MAFG SPAG9 RIT1 CDKN1A CXCL2 ATF3 ZBTB43 TAF9 DUSP1 INHBA EFR3A RASGEF1B MMP19 NRROS ETF1 RYBP NSMAF SGK1 JUN SH3BP5 HIC1 TMEM251 FERMT2 DDX5 KBTBD8 HOMER1 GPRC5A SNX9 SLC3A2 PTP4A1 TGIF1 OSGIN1 DUSP5 COL15A1 TMEM70 GNA13 ETS2 GEM ABL2 HAVCR2 TMEM217 JMJD1C MAFK EDN1 FNIP2	down	***
FLORIO_NEOCORTEX_BASAL_RADIAL_GLIA_DN	0.0000000	0.0000000	1.2709130	0.6236454	2.808861	160	FOXM1 KIF20A HJURP AK4 CDC45 PARPBP FANCI HBA1 TROAP CHEK2 BUB1B HBA2 NEK2 UGT8 CCNB1 CENPF TIMELESS POLQ UBE2T MND1 PBK KIF18B NDC80 DEPDC1 BRCA1 PHGDH DEPDC1B TTK GINS1 CDCA2 RACGAP1 IQGAP3 E2F8 GTSE1 KIF14 ANLN TRAIP ASPM PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 GRIN2A TPX2 CCNB2 MYBL2 PRC1 XRCC2 DTL NCAPD2 ZWINT MELK HMMR EXO1 KIF23 MKI67 KIF15 KNTC1 BUB1 TOP2A CENPL AURKA KIF2C POC1A RRM2 CDCA5 KIF11 FANCD2 LMNB1 SLC35G2 MAD2L1 CKAP2L RAD51AP1 BRIP1 BLM PSRC1 KNSTRN CKS1B NCAPG2 NUSAP1 CDK1 SERTAD4 BIRC5	up	***
GNF2_PCNA	0.0000000	0.0000000	1.0073180	0.7085173	2.808619	64	FOXM1 FANCI BUB1B CENPF KIF18B NDC80 TTK GINS1 RACGAP1 ASPM CDCA8 ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 PRC1 DTL ZWINT MELK HMMR MKI67 KIF15 TOP2A AURKA MCM7 RRM2 RAD54L KIF11 MCM3 DNAJC9 RAD51AP1 NUSAP1 CDK1 POLE2 BIRC5 GMNN FEN1 PA2G4 DLGAP5 GINS2 CDC20 MCM6 MCM5 MSH2 CCNA2 PRIM1 SHCBP1 PAXIP1 SMC2 CENPE	up	***
GNF2_CDC20	0.0000000	0.0000000	0.9969862	0.7440967	2.803900	51	FOXM1 KIF20A BUB1B CENPF KIF18B NDC80 TTK RACGAP1 ASPM PLK1 CDCA8 AURKB PTTG1 ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT MELK HMMR MKI67 BUB1 TOP2A AURKA KIF2C RRM2 KIF11 CKS1B NUSAP1 CDK1 BIRC5 GMNN SPAG5	up	***
GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN	0.0000000	0.0000000	1.1146645	-0.5348954	-2.792239	158	CXCL3 KMO IL1A DENND5A ZC3H12C IL1B SNX10 RAPGEF2 PLEKHF2 CCRL2 AQP9 SFR1 BCL2A1 PSMD5 ATF7IP2 IL23A CLCF1 PPP1R15B TNIP3 MAP3K8 RNF144B KLF6 PTX3 ARHGEF2 BTG3 IL10 CSRNP1 STAT5A TBC1D9 LINC00528 PPM1K PLAUR DRAM1 CLIC4 CXCL2 IRAK2 ID2 CCL4 CCSER2 PLEK TP53BP2 NINJ1 HCAR3 FLT1 IL6 SYNPO2 SOCS3 ARL5B PLK3 PPP1R15A WTAP ELOVL7 CCR7 CD83 OSM TNFRSF9 DENND4A ACSL1 PELI1 PTP4A1 SAV1 EHD1 TEX14 GPR84 PHF19 SOD2 ADORA2A-AS1 ETS2 CCL20 ICAM1 IL18 TNFAIP8 MIR155HG NBN GIMAP5 RIPK2 NLRP3 TRAF1 TTC32 MAP3K4 HNRNPC NFKBIA ADORA2A PMAIP1 CSF2 PIM3 NAF1 CLEC4E DCUN1D3 ZFP36 MSANTD3 YRDC RCSD1 CSF3 GJB2 CFLAR PTGS2 HIVEP1 NFKBIZ DUSP2 RNF19B	down	***
KOBAYASHI_EGFR_SIGNALING_24HR_DN	0.0000000	0.0000000	1.3877461	0.5920484	2.778269	231	HMGA2 DKK1 TFPI2 TRIP13 HELLS HJURP CDC45 MCM10 FANCI BUB1B NEK2 CCNB1 TIMELESS PBK KIF18B NDC80 DEPDC1 BRCA1 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 ASPM STIL PLK1 CDCA8 AURKB CENPA ECT2 ESPL1 CDC6 SOX9 TPX2 MCM4 MCM2 RAD54B TYMS CDC25A MYBL2 PRC1 ORC1 CCNF GALNT10 DTL ZWINT CDT1 SPDL1 NME1 RANBP1 MELK HMMR EXO1 KIF23 CEP55 CHAF1A MKI67 DCBLD2 KIF15 BUB1 EEF1E1 TOP2A PUS7 AURKA CARD10 POLA2 KIF2C MCM7 RRM2 KIF11 GPSM2 MCM3 LMNB1 CDC42EP1 DNAJC9 ORC6 MAD2L1 RAD51AP1 DSCC1 PKMYT1 BLM PSRC1 CKLF CKS1B NCAPG2 NUSAP1 ASF1B CDK1 POLE2 UCK2 RFWD3 BIRC5 GMNN POLR3K E2F1 UNG NCAPG STEAP1 GJB3 PSAT1 FEN1 EZH2 SPAG5 PA2G4 RNASEH2A RANGAP1 FAM86C1 TUBG1 DLGAP5 LMNB2 TUBB2A TK1 GINS2	up	***
GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN	0.0000000	0.0000000	1.1239150	-0.5242638	-2.774571	172	SLC31A2 HMOX1 FCN1 PECAM1 SNX10 COQ2 LMO2 CORO1C C5AR1 SLC15A3 MARCO NCF2 IL1RN SLC11A1 EPB41L3 FAM49A IGSF6 PILRA LILRB3 CD36 SPG21 SLC7A7 ASAH1 GM2A CLEC7A IFI30 ANPEP HLX SIRPA CD93 GRN TFEC ATP6V1B2 CST3 CFD DUSP3 SDCBP KLF4 PLAUR GAA CEBPA TPP1 CLIC4 CTSD ERP44 ITGAX FCER1G GCA DSE HEXB HCK RAB31 KCTD12 HK3 ATP6V0B TYROBP IFNGR1 CSTA IRF8 OGFRL1 ACSL1 PLCG2 RHOQ TNFSF13 ALDH3B1 CD74 RIN2 TIMP2 PEA15 MILR1 CD86 APLP2 LGALS3 CCR1 FCGRT KYNU RXRA CEBPD NLRP3 ALDH2 DAPK1	down	***
GSE11057_CD4_CENT_MEM_VS_PBMC_DN	0.0000000	0.0000000	1.1146645	-0.5239418	-2.772867	172	SIRPB1 SLC31A2 SIDT2 ABHD5 HVCN1 LTA4H FBP1 DPYSL2 PTPRE OSCAR TMEM170B CCDC88A BACH1 GFOD1 MYD88 SLC15A3 CD9 EPB41L3 IGSF6 LILRB3 NCEH1 MAN2B1 B3GNT5 MCTP1 SLC7A7 ARSB ASAH1 RASGRP4 RNF144B PICALM RB1 CES1 SRGN SPI1 ADAMTSL4 FBXL5 CFD DUSP3 KIAA0513 PIP5K1B PTAFR TNFSF15 DRAM1 CEBPA FAM49B KCNMB1 TLR4 TM6SF1 PLEK TM9SF2 PRCP FMNL2 CD160 SNAP23 CTSZ SNX2 OGFRL1 LGALS2 WDFY4 ACSL1 RHOQ TNFSF13 DGKG CPA3 SORT1 TFEB FPR2 ATP6V1A PDLIM1 APLP2 MEIS1 FCGRT RXRA BMP2K ITPRIPL2 RTN1 SEMA4A SCPEP1 CD19	down	***
GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_UP	0.0000000	0.0000000	1.0959293	-0.5297102	-2.768512	162	CXCL3 IL1A DENND5A USP12 ADTRP IL1B RAPGEF2 PLEKHF2 CCRL2 NEDD4L FOSL1 AQP9 SFR1 BCL2A1 PSMD5 IL23A STARD4 CLCF1 PTS HECW2 PPP1R15B BTG2 TNIP3 MAP3K8 PTX3 RGCC BTG3 TFRC TXN EIF1B IL10 CSRNP1 STAT5A PLAUR DRAM1 CDKN1A CXCL2 ID2 CCL4 CCSER2 DUSP1 PLEK INHBA HES1 TP53BP2 MAFF AREG IL6 RYBP SYNPO2 SOCS3 SERPINB8 ARL5B PLK3 PPP1R15A WTAP PTGER4 CCR7 CD83 DDX5 REL FAM177A1 DENND4A ACSL1 PELI1 PTP4A1 HIVEP2 FOXO3 RIN2 SAV1 DUSP5 GPR84 SOD2 ADORA2A-AS1 ETS2 ICAM1 IL18 MIR155HG RIPK2 NLRP3 UBE2D1 RND1 MAP3K4 HNRNPC NFKBIA EDN1 B3GNT2	down	***
WHITEFORD_PEDIATRIC_CANCER_MARKERS	0.0000000	0.0000000	1.1330899	0.6483061	2.764336	106	CDC45 NEK2 CCNB1 CCDC34 CENPF POLQ UBE2T MND1 PBK CDCA7 TTK CDCA2 CDK4 KIF14 NUF2 CDCA8 CENPA PTTG1 ESPL1 TPX2 GAPDH CCNB2 UHRF1 MCM4 TYMS CDC25A MYBL2 PRC1 ZWINT NME1 MELK NUDT1 PON3 MKI67 PAFAH1B3 BUB1 TOP2A AURKA MCM7 RRM2 CDCA5 KIF11 SOX4 MAD2L1 CKS1B NUSAP1 ASF1B GABRB2 CDK1 POLE2 BIRC5 E2F1 PSAT1 RECQL4 RNASEH2A DNMT1 ILF2 DLGAP5 LMNB2 TK1 DTYMK GINS2 ZNF300	up	***
GNF2_MCM4	0.0000000	0.0000000	0.9653278	0.7284834	2.760159	52	FOXM1 HELLS FANCI BUB1B KIF18B NDC80 TTK GINS1 RACGAP1 KIF14 ASPM CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS ZWINT MELK HMMR BUB1 TOP2A AURKA MCM7 RRM2 KIF11 MCM3 LMNB1 MAD2L1 RAD51AP1 ASF1B GMNN FEN1 PA2G4 GINS2 POLD1 CDC20 CENPM MCM6 MCM5	up	***
GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP	0.0000000	0.0000000	1.0864405	-0.5243219	-2.751874	165	IL1A USP12 ADTRP DCSTAMP RAPGEF2 MIR22HG CCRL2 ST3GAL6 NEDD4L FOSL1 TBC1D7 SFR1 IL23A STARD4 CLCF1 PTS HBEGF HECW2 PPP1R15B MAP3K8 KLF10 KLF6 NR4A1 RGCC SPRY2 TFRC TXN ATP6V1H TMEM38B IL10 CSRNP1 MOAP1 ACSL3 PLAUR COQ10B TNFSF15 STX3 SPAG9 RIT1 CDKN1A CXCL2 ID2 LBH DUSP1 CCDC59 INHBA HES1 TP53BP2 RASGEF1B NRROS FLT1 IL6 RYBP SYNPO2 NSMAF SGK1 PHACTR2 SOCS3 JUN ARL5B PLK3 TMEM251 PTGER4 FERMT2 CCR7 HOMER1 GPRC5A DENND4A SNX9 SLC3A2 PTP4A1 SAV1 OSGIN1 DUSP5 PIM1 ADORA2A-AS1 ETS2 GEM IL18 ABL2 MIR155HG RIPK2 FBXO30 NLRP3 MAFK EDN1 FNIP2 B3GNT2 PMAIP1 RABGEF1 PIM3 EGR1 NR4A2 SLC19A2 OSGIN2 HES4 SLC38A2 MSANTD3 DNAJB4	down	***
PHONG_TNF_TARGETS_UP	0.0000000	0.0000000	0.8266573	-0.6203061	-2.748046	60	CXCL3 EREG BMP2 EGR2 CD44 IER2 CCNL1 KLF10 KLF6 PTX3 BTG3 MCL1 BIRC2 ADAMTS9 CXCL2 ATF3 DUSP1 INHBA BTG1 IL6 JUN JUNB DUSP8 CD83 REL TNFRSF10B FOS DUSP5 ETS2 CCL20 GEM ICAM1 IER5 CEBPD EPHA2 NFKBIA LDLR CSF2 EGR1 FJX1 ZFP36	down	***
chr7p22	0.0000000	0.0000000	0.9865463	0.6772099	2.746006	71	C1GALT1 SLC29A4 ZDHHC4 ZNF12 IQCE ANKRD61 PMS2CL PMS2 EIF3B INTS1 FAM220A MICALL2 NUDT1 CARD11 RNF216P1 BRAT1 TMEM184A GPER1 MAD1L1 RNF216-IT1 WIPI2 SDK1 EIF2AK1 GPR146 AIMP2 KDELR2 GET4 C7orf50 COX19 CYP2W1 TTYH3 C7orf26 RBAK RNF216 SUN1 ADAP1 GRID2IP ZNF815P AP5Z1 PSMG3 USP42 TNRC18 RN7SKP130 FOXK1 CCZ1B	up	***
KANG_DOXORUBICIN_RESISTANCE_UP	0.0000000	0.0000000	0.9325952	0.7294233	2.742524	50	FOXM1 HJURP FANCI BUB1B POLQ PBK GINS1 ASPM PLK1 CDCA8 CENPA CDC6 TPX2 MCM4 TYMS PRC1 ZWINT HMMR MKI67 BUB1 TOP2A AURKA POLA2 RRM2 LMNB1 MAD2L1 RAD51AP1 DSCC1 NCAPG2 NUSAP1 ASF1B CDK1 BIRC5 NCAPG TK1 DTYMK CDC20 CENPM	up	***
GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP	0.0000000	0.0000000	1.1146645	-0.5165242	-2.741877	178	SLC31A2 HMOX1 FCN1 LTA4H PTP4A2 PID1 HSD17B11 CD44 FLVCR2 C5AR1 NCF2 IL1RN EPB41L3 IGSF6 TRIB1 PILRA LILRB3 FGR DPEP2 SPG21 ASAP1 HBEGF CD33 SLC7A7 BEST1 ASAH1 ENTPD1 CLEC7A IFI30 PICALM SIRPA CD93 TCF7L2 FBXL5 PTPN12 ARRB1 KIAA0513 CASP1 YBX3 ITM2B KLF11 CEBPA DENND3 PLBD1 TMBIM1 HPSE ARAP3 EVI2A LIN7A HCK HCAR3 SGK1 CTSS TREM1 SNX2 GMFG PTGER2 SERPINB6 RALB PPM1F ACSL1 AGFG1 PELI1 TNFSF13 ATG3 ALDH3B1 RIN2 CD1D TGIF1 CD86 APLP2 SOD2 RXRA RTN1 CDC42EP3 CEBPD NLRP3 UBE2D1 MEGF9 SCPEP1 ICAM3 LYST CREG1 WDFY3	down	***
GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN	0.0000000	0.0000000	1.1053366	-0.5160808	-2.739271	180	FBP1 CAT DPYSL2 PTPRE RCOR1 LMO2 SAMHD1 FCER1A ST3GAL6 MYD88 CLEC10A APIP P2RY13 CD1C IL1RN IGSF6 ANXA1 EIF4A1 SH2B3 MCTP1 CD33 LMNA CLEC7A CSGALNACT2 KLF10 SIRPA RGCC GRN MCL1 CST3 TIPARP ARRB1 DUSP3 PPT1 AHNAK CASP1 LIMS1 KLF4 CPVL STX3 PLBD1 COTL1 ITGAX ATF3 VIM ID2 CD302 FCER1G GNAQ RUFY3 HEXB RAB31 KCTD12 TYROBP CSTA RCAN1 PSTPIP2 OGFRL1 LGALS2 CST7 TNFSF13 ATG3 SORT1 PEA15 CD1D CD86 GNG5 FCGRT TOB1 ETS2 ICAM1 LDLRAD4 IL18 CPQ FKBP1A RTN1 SEMA4A RTN4 CEBPD ALDH2 ACTB S100A4 DAPK1 CD1E CREG1 RNH1 GRPEL1 CACNA2D3 CHP1 TMEM43 AOAH NDFIP1 ATP1B1	down	***
MODULE_5	0.0000000	0.0000000	1.4390257	-0.4709417	-2.728525	384	EPAS1 SLPI ACP5 CD52 HMOX1 FCN1 TEK DLC1 PECAM1 CD55 GATA2 PGC IL1B FABP4 MNDA CLEC3B FBP1 CYP27A1 LPXN EMP2 CYP4B1 LIPA RAMP2 CDH5 INSIG1 ENG FOLR1 LPL CD44 LMO2 PPP4R1 LDB2 CAV1 CITED2 CALCRL SLC39A8 MAL ALAS1 MARCO TGFBR3 MSLN NEDD9 IL1RN FUCA1 EPB41L3 TGFBR2 LILRB3 RFTN1 HSPG2 FGR HEG1 APOD ANXA1 TBX2 SLC7A7 CACNA2D2 ASAH1 CSRP1 CYB5A MALL RNASE1 CAV2 PTX3 LCP1 LAIR1 NR4A1 GRN CES1 SRGN APOC1 CD37 RHOB PTPN12 MAP2K3 CFD BIRC2 AOC3 PLAUR DAB2 THBS1 CLDN5 GRK5 MYO1B CCL3 LAPTM5 CDKN1A CADM1 RBMS1 PTPRC CXCL2 AQP4 SELL HOPX CD302 SFTPD CD53 FCER1G PER1 ALOX5AP ADIPOR2 WFS1 VAMP5 IL7R MYH11 HLA-DQA1 HES1 MAFF ANXA3 CRIM1 VWF ARHGDIB HCK EMP3 IL6 SOCS3 SLCO2B1 AQP3 LAMB2 CYB5R1 RAB31 LTBP2 SFTPB RAC2 ST6GALNAC4 JUNB ATP11A RHOG IFNGR1 PPP1R15A GMFG MFAP4 SNX1 RPS6KA1 FSTL3 GPRC5A CST7 SNRK FGFR4 CD34 ACSL1 CD151 RRAS MSMO1 NKG7 TIMP2 TGFB1 SFTPC SERPINB1 LRRC32 PCDH17 PIM1 ORM2 CCR1 FCGRT RGS2 CLEC2B ETS2 SOD3 ICAM1 GPX3	down	***
GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_DN	0.0000000	0.0000000	1.0959293	-0.5151273	-2.726325	169	CXCL3 IL1A DENND5A IL1B RAPGEF2 PLEKHF2 AQP9 QKI SFR1 STX11 BCL2A1 PSMD5 EPB41L3 FAM49A IGSF6 PILRA IL23A CLCF1 ADA PPP1R15B MTF1 TNIP3 MAP3K8 RNF144B PTX3 NFE2L2 EPM2AIP1 BTG3 CASP5 EIF1B IL10 STAT5A ARRB1 LINC00528 BIRC2 DRAM1 CLIC4 NFKB1 CXCL2 IRAK2 ID2 CCL4 PNRC1 HCK HCAR3 IL6 SYNPO2 SOCS3 OASL SERPINB8 ARL5B PLK3 DNAJA1 CD83 TNFRSF9 TNFRSF10B DENND4A ACSL1 PELI1 HIVEP2 RIN2 PIK3AP1 AZIN1 SAV1 EHD1 NAB1 GPR84 KCNA3 SOD2 TAGAP ADORA2A-AS1 PDE4B CCL20 ICAM1 IL18 TNFAIP8 MIR155HG NBN IER5 TAB2 GIMAP5 RIPK2 NLRP3 TRAF1 RND1 HNRNPC NFKBIA MCOLN2 SAMSN1 LDLR PMAIP1 FNBP1 PIM3	down	***
KONG_E2F3_TARGETS	0.0000000	0.0000000	1.0276699	0.6571261	2.725812	85	KIF20A HJURP BUB1B CCNB1 CENPF UBE2T PBK DEPDC1 BRCA1 RACGAP1 IQGAP3 PLK1 NUF2 CDC6 TPX2 E2F3 FIGNL1 RBBP8 TYMS PRC1 CCNF NCAPD2 SPDL1 MELK HMMR MKI67 BUB1 TOP2A AURKA KIF2C CDCA5 RAD54L KIF11 MCM3 CHAF1B LMNB1 RAD51AP1 SKP2 INCENP NCAPG2 NUSAP1 ASF1B CENPH NCAPG DNA2 FEN1 EZH2 CCNE1 DLGAP5 TACC3 TK1 CENPQ CDC7 CENPK CDC20 RPRD1B CCNA2 PRIM1 SHCBP1 RAD51 F13A1 SMC2 UBE2C FBXO45 GP1BA	up	***
ZHAN_MULTIPLE_MYELOMA_PR_UP	0.0000000	0.0000000	0.9436322	0.7738207	2.724507	38	TRIP13 FOXM1 MCM10 FANCI BUB1B NEK2 CCNB1 CCDC34 UBE2T DEPDC1B TTK RACGAP1 E2F8 KIF14 ASPM NUF2 TPX2 CCNB2 TYMS PRC1 TOP2A CENPL AURKA RRM2 SPC24 DSCC1 NUSAP1 CDK1 BIRC5 EZH2 DLGAP5	up	***
GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP	0.0000000	0.0000000	1.0672100	-0.5184900	-2.721265	165	CXCL3 PHACTR1 PPARG DCSTAMP P2RY1 MIR22HG INSIG1 LPL EGR2 CCRL2 GFOD1 ST3GAL6 CORO1C NEDD4L FOSL1 GPCPD1 TBC1D7 TBC1D2 TRIB1 EIF4A1 B3GNT5 SGMS2 HECW2 LINC01010 ZBTB21 KLF10 EIF4E CRTAM ZFYVE16 TXN TMEM38B TUBB6 FABP5 CSRNP1 NRARP MOAP1 DUSP3 ADO ACSL3 DAB2 TNFSF15 SPAG9 RIT1 CDKN1A CXCL2 M6PR ZBTB43 TAF9 DUSP1 INHBA UBASH3B RASGEF1B MMP19 ETF1 BCAR3 NSMAF SGK1 JUN SH3BP5 HIC1 TMEM251 FERMT2 KBTBD8 HOMER1 GPRC5A SNX9 SLC3A2 ADNP2 AKIRIN2 DUSP5 COL15A1 TMEM70 GNA13 ETS2 CCL20 GEM ABL2 CDC42EP3 HAVCR2 TMEM217 JMJD1C EDN1 FNIP2	down	***
GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_UP	0.0000000	0.0000000	1.0768682	-0.5162300	-2.716293	168	SIRPB1 CXCL3 EREG CD52 FCN1 OLR1 ASGR1 PPARG GLIPR2 IL1B LTA4H PTP4A2 PTPRE MBOAT2 SIK1 LPL CCRL2 PRAM1 AQP9 CLEC10A ARL8B MARCO BCL2A1 CD1C IL1RN FRAT1 FGR EDEM1 DPEP2 ADA SGMS2 TNIP3 LITAF CSGALNACT2 ZNF697 NDEL1 SLC25A37 ZMIZ1 MAP2K3 FABP5 ITPRIP SLC46A2 PLAUR STK17B ITGAX CXCL2 SELL MMP19 ETF1 S1PR4 HCAR3 FRY AREG CD48 TREM1 CSTA WTAP GPR183 OSM PTGER2 MALT1 GRASP CXCL5 TNFRSF10B LGALS2 TAGLN2	down	***
GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP	0.0000000	0.0000000	1.2039752	0.5960907	2.709267	178	FOXM1 KIF20A CDC45 TICRR PARPBP MCM10 BUB1B NEK2 CENPF MND1 PBK KIF18B DEPDC1 PIF1 TTK CDCA2 RACGAP1 E2F8 GTSE1 ANLN POLE ASPM STIL PLK1 NUF2 AURKB CENPA ECT2 CDC6 TPX2 CCNB2 UHRF1 MYBL2 ORC1 CCNF DTL MUC20 CCT2 SPDL1 ITGA2 MELK HMMR EXO1 KIF23 CEP55 MKI67 BUB1 AUNIP TOP2A AURKA EME1 CLSPN RRM2 CDCA5 PASK FANCD2 MCM3 CDC25C LIG1 CHEK1 MAD2L1 CKAP2L RAD51AP1 SPC24 BRIP1 CCDC138 PSRC1 INCENP KNSTRN CKS1B NCAPG2 CBX5 CDK1 FAM221A CENPH BIRC5 FAM114A1 NCAPG DNA2 KIF2A PSAT1 FEN1 NUP205 SPAG5 CENPP NMRAL1 TACC3 KIF22 TK1 ESCO2 KIF20B CENPK CKAP5 CENPM MCM6 CKAP2 PRSS16 CCNA2 PRIM1 PRR11 SHCBP1 RFC5 RAD51 ZWILCH ARHGAP11A NDUFS8 CPOX MXD3 SMC2 SYNRG CENPE PFDN4 UBE2C MRPL20 E2F7 NUP93 KIF24	up	***
GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN	0.0000000	0.0000000	1.1053366	-0.5106911	-2.708448	182	SIRPB1 SLC31A2 HMOX1 MIR22HG PID1 RCOR1 ST3GAL6 FLVCR2 C5AR1 STX11 IL1RN TRIB1 PILRA LILRB3 EIF4A1 MCTP1 HBEGF LMNA EMILIN2 KLF10 SIRPA RGCC GRN MCL1 CD58 CST3 FBXL5 ARRB1 AHNAK SDCBP KIAA0513 BST1 TNFSF12 PLAUR ITM2B GAA CEBPA CTSD ATF3 VIM HPSE ID2 CD302 ARAP3 EVI2A GNAQ LIN7A HEXB HCAR3 SGK1 PHACTR2 PGD TYROBP TREM1 PTGER2 OGFRL1 LGALS2 ACSL1 TNFSF13 ALDH3B1 SORT1 TIMP2 CD86 GABARAPL1 CCR1 FCGRT RXRA ICAM1 CPQ FKBP1A RTN1 SEMA4A CDC42EP3 CEBPD TIAM1 NLRP3 ALDH2 UBE2D1 ULK2 DAPK1 SIGLEC9 CREG1 WDFY3 DUSP6 AOAH FTL ZYX FPR1 NDFIP1	down	***
GSE11057_PBMC_VS_MEM_CD4_TCELL_UP	0.0000000	0.0000000	1.0574636	-0.5146845	-2.701292	165	SIRPB1 SLC31A2 CD300LF HMOX1 SWAP70 ASGR1 HVCN1 LTA4H CYP27A1 TUBB1 OSCAR TMEM170B CCDC88A FCER1A C5AR1 SLC15A3 P2RY13 CD1C IL1RN TET2 EPB41L3 FAM49A IGSF6 LILRB3 ZEB2 TNFRSF8 PLA2G7 B3GNT5 SIRPB2 SLC7A7 SGMS2 ASAH1 IFI30 RNF144B HDC ANPEP PTX3 CES1 TFEC SRGN SPI1 ARL11 CYBRD1 BST1 SLC46A2 PIP5K1B PTAFR CEBPA TLR4 TM6SF1 CD300LB CD8B RBP7 FMNL2 CD160 CTSS RAB31 HK3 TREM1 LPCAT2 CXCL5 LGALS2 WDFY4 SORT1 TCF4 FPR2 CD86 CCR1 FCGRT KYNU RXRA BMP2K IL18 ITPRIPL2 RTN1 SCPEP1 CD19 LYST CACNA2D3 FCRL1 ATP6V0A1 DUSP6 CLEC4E AOAH NFAM1 PTGS1 GNG11	down	***
GNF2_TNFRSF1B	0.0000000	0.0000001	0.8012156	-0.6323857	-2.690211	52	FCN1 PECAM1 HSD17B11 MYD88 NCF2 IGSF6 PILRA LILRB3 FGR DPEP2 SLC7A7 PPT1 CASP1 CPVL COTL1 FCER1G DUSP1 CMTM6 HCK CTSS TYROBP RHOG CD1D DOK2 CCR1 RGS2 ARRB2 S100A4 THEMIS2 SH3BGRL3 AOAH	down	***
GNF2_CCNB2	0.0000000	0.0000000	0.9101197	0.7094783	2.688151	52	FOXM1 KIF20A BUB1B CENPF PBK KIF18B NDC80 TTK RACGAP1 ASPM CDCA8 PTTG1 ESPL1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT MELK HMMR BUB1 TOP2A AURKA KIF2C RRM2 KIF11 NUSAP1 CDK1 BIRC5 GMNN FEN1 SPAG5	up	***
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR	0.0000000	0.0000000	1.0768682	0.6276297	2.686842	112	TRIP13 KIF20A PARPBP NUP107 NEK2 CCNB1 CENPF TIMELESS UBE2T DEPDC1 TTK RACGAP1 E2F8 ANLN ASPM NUF2 CDCA8 CENPA PTTG1 CCNB2 RBBP8 UHRF1 MCM2 MYBL2 PRC1 MCM8 RANBP1 MELK HMMR EXO1 KIF23 CEP55 KNTC1 BUB1 TOP2A ODF2 MCM7 POC1A RAD54L KIF11 MCM3 LMNB1 TOPBP1 DNAJC9 MAD2L1 DCTPP1 KNSTRN NUSAP1 CDK1 BIRC5 E2F1 NEIL3 EZH2 SPAG5 FGFR1OP DLGAP5 KIF22 DTYMK POLD1 MAGOHB CENPK CDC20 PLEK2 CKAP2 TDP1 GINS3	up	***
GSE10325_CD4_TCELL_VS_MYELOID_DN	0.0000000	0.0000000	1.0476265	-0.5108978	-2.681418	165	SLC31A2 KMO SIDT2 TSPAN4 OSBPL11 HHEX LTA4H SNX10 SLC6A12 FIG4 LYL1 LY86 LMO2 CCDC88A GFOD1 CORO1C AQP9 MYD88 SLC15A3 P2RY13 CD1C SLC11A1 FAM49A TRIB1 LILRB3 FGR SLC7A7 ENTPD1 GM2A CLEC7A IFI30 SIRPA TUBB6 MSR1 MAP2K3 TBC1D9 YBX3 PLAUR DENND3 CLIC4 CDKN1A ITGAX KCNMB1 PLEK DSE HEXB HCK PRCP RNF141 MTMR14 RAB31 STX7 IRF8 PLCG2 RHOQ TNFSF13 DGKG RIN2 IRF5 PEA15 CD1D CBFA2T3 CD86 APLP2 CCR1 KYNU RGS2 RXRA ICAM1 OPN3 CDKN1C ALDH2 MEGF9 SCPEP1 METTL7A LYST P2RX1 THEMIS2	down	***
GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN	0.0000000	0.0000000	1.1053366	-0.5018223	-2.679105	185	SOWAHC ZC3H12C IL1B FABP4 CLDND1 BMP2 EGR2 OTUD1 CCRL2 CITED2 CDC42EP2 STX11 BCL2A1 IER2 CCNL1 SDE2 BTG2 MAP3K8 PICALM KLF6 NDEL1 SPRY2 SRGN ARHGEF2 MCL1 TIPARP IL10 CSRNP1 TLE4 FOXO1 ACSL3 PLAUR ID3 ZFAND5 KLF7 P2RY2 ATF3 VIM C9orf72 ID2 CCL4 PNRC1 FRMD4A DUSP1 PLEK SPRYD7 USP16 RASGEF1B NRROS RBM39 ETF1 SLC25A25 RYBP SGK1 ETV3 JUN MTMR14 KCTD12 HSPA1B RAPGEF1 DHX15 SKIL IFRD1 CD83 DDX5 OSM MALT1 ATL2 REL FOS CDK17 MAPK8 EHD1 TGIF1 DUSP5 PIM1 PLSCR4 GPR84 SOD2 TOB1 GTF2B GEM ICAM1 IER5 RIPK2 PTCH1 MEX3C TNFSF9 DNAJA2 MAN1C1 RABGEF1 HERPUD1 ZNF800 CLEC4E SLC38A2 ZNF654 DNAJB4 CD69 WDR47 BCL10 TRIM13 IRF1	down	***
GNF2_RRM2	0.0000000	0.0000000	0.9101197	0.7605426	2.677757	38	FOXM1 BUB1B CENPF KIF18B NDC80 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS ZWINT MELK HMMR MKI67 BUB1 TOP2A AURKA RRM2 KIF11 MCM3 LMNB1 NUSAP1 CDK1 BIRC5 GMNN DLGAP5 CDC20 CENPM MCM6	up	***
GNF2_TTK	0.0000000	0.0000000	0.9101197	0.7581135	2.669205	38	FOXM1 HJURP FANCI BUB1B CENPF KIF18B NDC80 TTK RACGAP1 ASPM TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT CCT2 MELK HMMR TOP2A KIF2C KIF11 NUSAP1 CDK1 GMNN FEN1	up	***
BOQUEST_STEM_CELL_DN	0.0000000	0.0000000	1.1053366	-0.4955162	-2.668134	198	SEMA6A RAMP3 SWAP70 TEK PECAM1 ENDOU RASIP1 HHEX GATA2 TIE1 PTPRE THBD PTPRB CDH5 ENG KL ARHGEF15 EMCN LMO2 SOX17 CCRL2 GFOD1 KANK3 S1PR1 STX11 NEDD9 GIMAP6 EOGT SCARF1 PDE2A ERG KIAA0355 MMRN2 SH2B3 ZNF385D PTPRM MCTP1 HBEGF RAPGEF4 NLK ABCG1 PCDH12 RNASE1 ADRB2 IL18R1 LHX6 CD93 SRGN MYCT1 FLI1 FABP5 TBC1D9 CLEC1A TSPAN12 ADAMTS9 SOCS2 CLDN5 MYRIP SSH1 LAPTM5 DOCK9 SELP JAM2 ARAP3 HLA-DQA1 ANXA3 VWF CLIC5 RPS6KA2 FAM107A FLT1 AREG CREM BCAR3 SEC14L1 CAPN11 CARD8 RCAN1 PODXL ENPP4 GMFG	down	***
GNF2_CDC2	0.0000000	0.0000000	0.9325952	0.6929047	2.667117	56	FOXM1 KIF20A HJURP FANCI CENPF KIF18B NDC80 TTK E2F8 ASPM CDCA8 PTTG1 TPX2 CCNB2 MCM2 TYMS MYBL2 PRC1 CCNF ZWINT MELK HMMR MKI67 KIF15 TOP2A AURKA RRM2 KIF11 DNAJC9 NUSAP1 CDK1 BIRC5 NCAPG FEN1 EZH2 DLGAP5 GINS2 CDC20 CKAP2 CCNA2 PRIM1 SHCBP1 SMC2 CENPE UBE2C	up	***
GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP	0.0000000	0.0000000	1.1953445	0.5893013	2.666117	173	HJURP KCNK5 PARPBP MCM10 GMDS BDH1 GPT2 ELOVL6 CHEK2 BUB1B CCNB1 UBE2T KIF18B NDC80 PIF1 IFI27L1 DEPDC1B CDCA7 TTK CDCA2 E2F8 SLC27A2 ANLN ASPM NUF2 YEATS4 AURKB ECT2 CDC6 SFXN1 TPX2 RBBP8 TYMS CDC25A PRC1 DTL XPOT MELK EXO1 MKI67 KIF15 BUB1 TOP2A CENPL AURKA VANGL1 POLA2 SAE1 KIF2C POC1A RAD54L KIF11 CHEK1 ORC6 MAD2L1 CENPO SPC24 INPP4B MBOAT1 MNAT1 THOP1 CKS1B TMEM106C ASF1B CDK1 UCK2 BIRC5 TESC PSAT1 EZH2 SPAG5 DIAPH3 CCNE1 DLGAP5 TACC3 LMNB2 KIF22 TMEM237 DTYMK GINS2 TCEA1 LRRC20 SAP30 RNF187 LIMA1 FAF1 MCM6 MCM5 WDYHV1 ALG8 SUV39H2 CCNA2 PRIM1 DCPS BLVRB RAD51	up	***
GNF2_CENPF	0.0000000	0.0000000	0.9214260	0.6925339	2.665796	55	FOXM1 HJURP MCM10 FANCI CENPF KIF18B NDC80 TTK E2F8 ASPM CDCA8 PTTG1 TPX2 CCNB2 MCM2 TYMS MYBL2 PRC1 CCNF ZWINT HMMR MKI67 KIF15 TOP2A AURKA MCM7 RRM2 KIF11 MCM3 DNAJC9 NUSAP1 CDK1 BIRC5 FEN1 DLGAP5 DTYMK GINS2 CDC20 CKAP2 CCNA2 PRIM1 SHCBP1 SMC2 CENPE UBE2C	up	***
NAGASHIMA_EGF_SIGNALING_UP	0.0000000	0.0000001	0.7881868	-0.6266112	-2.665646	52	SOWAHC MIR22HG SIK1 FOSL1 NEDD9 TRIB1 IER2 HBEGF KLF10 KLF6 NR4A1 MCL1 TIPARP ID3 ATF3 ARC DUSP1 HES1 MAFF AREG RYBP JUN JUNB FOS FOSB DUSP5 PLEKHO2 ETS2 GEM EPHA2 EDN1 EGR1 NR4A2 ZFP36 DNAJB1 BCL10 NR4A3 KBTBD2 DUSP2	down	***
GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN	0.0000000	0.0000000	1.0768682	-0.5026107	-2.664109	181	SLC31A2 HMOX1 MCOLN1 ASGR1 PECAM1 FBP1 PTPRE ST3GAL6 FLVCR2 C5AR1 TBC1D2 MARCO NCF2 IL1RN LAMP1 SLC11A1 EPB41L3 IGSF6 PILRA LILRB3 CD36 SPG21 SLC7A7 BEST1 CLEC7A ITGA5 ANPEP SIRPA CD93 TCF7L2 ATP6V1B2 CST3 ZMIZ1 CFD SDCBP KIAA0513 KLF4 PLAUR ZCCHC24 GAA CEBPA CTSD ATG7 P2RY2 KCNMB1 HPSE FCER1G GNAQ HEXB VAMP3 RAB31 KCTD12 HK3 TYROBP RHOG IFNGR1 PSTPIP2 CAP1 ALDH3B1 RIN2 MILR1 GALC APLP2 LGALS3 DOK2 FCGRT TSPO ETS2 RXRA ARRB2 RTN4 NLRP3 ALDH2 ACTB S100A4 DAPK1 GLUL HEBP1 CREG1 LPAR6 WDFY3 FEZ2 DMXL2	down	***
GNF2_HMMR	0.0000000	0.0000000	0.8870750	0.7249135	2.658622	46	FOXM1 KIF20A BUB1B CENPF KIF18B NDC80 TTK E2F8 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 MCM2 TYMS PRC1 ZWINT MELK HMMR MKI67 BUB1 TOP2A AURKA RRM2 KIF11 NUSAP1 CDK1 BIRC5 GMNN FEN1 DLGAP5 GINS2	up	***
GNF2_ITGB2	0.0000000	0.0000001	0.7881868	-0.6322732	-2.657818	47	PECAM1 HSD17B11 MYD88 FGR DPEP2 MCL1 FBXL5 CASP1 OSTF1 ITGAX FCER1G CMTM6 HCK TYROBP RHOG PTGER4 GMFG BIN2 DOK2 RGS2 SELPLG ARRB2 ACAP2 S100A4 ICAM3 THEMIS2 IQGAP1 SH3BGRL3 AOAH IRF1 PLCB2 MYO1F APOBR TNFRSF1B PYCARD IL10RA TMEM127 HCLS1	down	***
GNF2_RRM1	0.0000000	0.0000000	0.9865463	0.6406699	2.657550	85	FOXM1 FANCI BUB1B CENPF KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 KIF14 ASPM CDCA8 AURKB CCNB2 MCM4 MCM2 TYMS PRC1 DTL CCT6A ZWINT MELK HMMR MKI67 PCCB TOP2A AURKA MCM7 RRM2 KIF11 MCM3 RAD51AP1 NUSAP1 CDK1 BIRC5 GMNN FEN1 PA2G4 CHCHD3 DLGAP5 SSRP1 DTYMK GINS2 ANP32E CDC20 CENPM MCM6 MCM5 SNRPD1 MSH2 CCNA2 PRIM1 SHCBP1 SMC2 CENPE PAICS UBE2C	up	***
CUI_TCF21_TARGETS_2_DN	0.0000000	0.0000000	1.7268308	-0.4255715	-2.655372	742	SEMA3G EPAS1 CXCL3 PRX ARHGAP31 LPIN2 COL25A1 SLC12A6 TEK PDLIM2 EDNRB FGD5 USP12 SECISBP2L CD55 HHEX SOWAHC TBX3 CPEB2 FABP4 MNDA DPYSL2 GIMAP8 RAPGEF2 CYP4B1 ST6GALNAC3 BTNL9 LIPA LRRFIP1 THBD PTPRB CDH5 ARHGEF15 FYN EMCN LMO2 TMOD3 SOX17 CCRL2 ST3GAL6 KANK3 LDB2 MYADM HEATR5B CITED2 THAP2 CALCRL QKI EML1 YPEL5 C8orf58 ARL8B FBXO3 TGFBR3 NEDD9 GIMAP6 SLCO2A1 CBL TGFBR2 FAM49A ABCB1 TEX2 ZEB2 DNAJB14 PDE2A GINM1 TXNIP ERG ARHGAP29 ZBTB4 CD36 ANXA1 UBR3 KIAA0355 WWC2 MMRN2 SH2B3 SEMA3B SLC36A4 TACC1 HECW2 RAPGEF4 LIFR LATS2 RAP1A CHMP1B TMEM204 CLEC14A SERINC1 CYYR1 RANBP9 NLK SPIRE1 CSGALNACT2 HIPK3 PCDH12 CAV2 HLX PAG1 ZBTB8A DACH1 SLAIN2 GATA3 SIRPA CRK ANKRD29 PPP1R13B ZFYVE16 SRGN ITSN2 SOX7 MCL1 MYCT1 FOXC2 TIPARP ATP10A FLI1 PTPN12 AGO4 AMOTL1 ARRB1 SYNPO MTMR6 DUSP3 TLE4 EXOC3L2 AHNAK CCDC82 SORBS1 PTPRO CLEC1A DENND6A NOSTRIN PPM1K LIMS1 TCP11L2 TSPAN12 DAAM2 RNFT1 KLF4 NES FAM76A COQ10B ROCK1 THBS1 TMED5 TPP1 GRK5 MYO1B NPR3 FAM49B TMBIM1 C1QTNF7 PER2 RBMS1 PTPRC VIM CTBS TADA2B ARHGEF26 HOPX CYP20A1 JAM2 TLR4 SHE ILDR2 VAMP5 CALM2 DEGS1 CRIM1 BACE1 AKIRIN1 IKZF5 LMBRD1 TANC1 HSDL2 LIN54 SACM1L NRROS CLIC5 USP25 ARHGAP17 TMEM9B KANK1 MYO1C FMNL2 FRY FLT1 ELF1 VPS37A NSMAF SGK1 CTSS EBAG9 SNAP23 MAGI2 CABLES1 TMTC1 LRCH1 RASSF10 SH3BP5 CPEB4 ETS1 MSRB3 HSPA1B FOXN2 APBB2 JAK1 TBC1D12 AK1 RCAN1 PTGER4 FERMT2 ENPP4 IFRD1 TTC14 ACKR3 MBNL2 FRYL IDS FAM43A MALT1 SERPINB6 HOMER1 TRAK2 PREX2 RALB SNRK CELF2 AGFG1 GPRIN3 CTTNBP2 CALM1 HIVEP2 ICAM2 RIN2 ZNF175 ING3 MME GIMAP1 SPOP EMC7 CHPT1 STXBP3 STRN DCAF5 ITGA9 MTMR2 CBFA2T3 GALC MAP3K2 PCDH17 PLSCR4 TOB1 NBEAL1 MACF1 RGS2 PGGT1B SERINC3 PDE4B INO80D GEM ARAP2 TNFAIP8 SCN7A EPN2 IQSEC1 CDC42EP3 ACAP2 CXCR4 CDKN1C HSP90AA1 TTLL7 TDRP TBC1D1 POLR2M CREBBP ULK2 PARVA MBD5 VSIG10 LYSMD3 NFKBIA GLRX2 RAPGEF3 ABI3 TIMP3 B3GNT2 MTUS1 LYST FAM126B PRKG1 MMD KIF1B TMCC3 RORA FAM13C DOCK4 GIMAP4 EHD4 PURB RNF13 EHD3	down	***
CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP	0.0000000	0.0000000	1.1512205	0.5911954	2.644720	157	TRIP13 FOXM1 HELLS KIF20A HJURP FANCI BUB1B NEK2 TRNP1 CCNB1 CENPF IGF2BP3 FLVCR1 PBK KIF18B TTF2 NDC80 DEPDC1 DEPDC1B CDCA7 TTK RACGAP1 E2F8 KIF14 ANLN ASPM NUF2 AURKB PTTG1 ECT2 CDC6 SOX9 TPX2 CCNB2 H19 MCM2 PRC1 DTL PDE9A ZWINT KIF23 CEP55 MKI67 WASF1 PAFAH1B3 TOP2A AURKA KIF2C CDCA5 PKM FHOD3 KIF11 LMNB1 SOX4 SALL2 CD24 ORC6 MAD2L1 CKAP2L RAD51AP1 BACE2 DSCC1 DDR1 TMED3 NUSAP1 CDK1 TNFRSF21 BIRC5 FEN1 EZH2 TMEM51 CCNE1 DLGAP5 MAPK13 SALL4 PAPLN DBN1 GALNT7 MARCKSL1 CDC7 ETV4 CENPK SASS6 CDC20 ASRGL1 SLC1A5 MARCKS NT5DC2 CKAP4 CCNA2 PRR11 SHCBP1 HK2	up	***
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP	0.0000000	0.0000000	0.9214260	0.6506098	2.638146	71	HMGA2 KIF20A HJURP NEK2 CCNB1 CENPF PBK EFNA3 GTSE1 ASPM CDCA8 CENPA ESPL1 TPX2 CCNB2 MCM4 TNC SCG5 MELK HMMR CEP55 MKI67 BUB1 TPBG MSX2 TOP2A KIF2C RRM2 KIF11 GPSM2 NUSAP1 APLP1 CDK1 BIRC5 CDH3 CRLF1 DLGAP5 AHNAK2 COL11A1 CDC20 CDH11 CCNA2 FBN2 CENPE UBE2C NPTX2 NCAPH ROR2 MLLT11	up	***
GSE11057_CD4_EFF_MEM_VS_PBMC_DN	0.0000000	0.0000000	1.0376962	-0.4961729	-2.628710	173	SLC31A2 CD300LF MS4A7 HVCN1 LTA4H CAT PTPRE TMEM170B CCDC88A GFOD1 CORO1C AQP9 SLC15A3 MEF2A CD9 TET2 EPB41L3 LILRB3 ACER3 TNFRSF8 B3GNT5 SLC7A7 ARSB ASAH1 GNGT2 SRGN SPI1 ADAMTSL4 ATP6V1B2 FBXL5 CFD SDCBP KIAA0513 PIP5K1B TPP1 ITGAX C9orf72 TLR4 TM6SF1 CD300C PLEK SNN PRCP FMNL2 CD160 PGD SNAP23 RGS18 HK3 CTSZ TREM1 STX7 LGALS2 WDFY4 ACSL1 RHOQ TNFSF13 CD74 SORT1 TCF4 PEA15 NAPSB ATP6V1A PDLIM1 APLP2 RXRA BMP2K BNIP3L RTN1 SCPEP1 DAPK1 SIGLEC9 ARPC5 LYST CREG1 LYZ ATP6V0A1 DUSP6 AOAH FTL PLXDC2 NFAM1 PTGS1 MFSD1 DAPP1	down	***
CROONQUIST_IL6_DEPRIVATION_DN	0.0000000	0.0000000	0.9759947	0.6299623	2.623155	88	TRIP13 FOXM1 CDC45 FANCI BUB1B CCNB1 BRCA1 GINS1 KIF14 TRAIP GMPS SPP1 STIL PLK1 AURKB CENPA PTTG1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS CDC25A MYBL2 CCNF ZWINT HMMR CHAF1A MKI67 KNTC1 BUB1 TOP2A AURKA KIF2C MCM7 RRM2 KIF11 MCM3 LIG1 CHEK1 MAD2L1 SKP2 CKS1B CDK1 POLE2 SPAG5 KIF22 TK1 DTYMK ANP32E POLD1 CDC20 HMGA1	up	***
GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN	0.0000000	0.0000000	1.0276699	-0.4928836	-2.611283	173	IL1A DENND5A IL1B SNX10 RAPGEF2 PLEKHF2 AQP9 QKI SFR1 STX11 BCL2A1 PSMD5 FAM49A PILRA IL23A CLCF1 ADA PPP1R15B MTF1 TNIP3 MAP3K8 RNF144B PTX3 TMEM123 NFE2L2 EPM2AIP1 BTG3 TCF7L2 EIF1B IL10 STAT5A LINC00528 BIRC2 PPM1K PTAFR DRAM1 CLIC4 NFKB1 CXCL2 IRAK2 CCL4 PNRC1 CCSER2 HCK HCAR3 IL6 SYNPO2 SOCS3 OASL SERPINB8 PLK3 DNAJA1 FOXN2 CD83 PI4K2B TNFRSF9 TNFRSF10B ACSL1 PELI1 RIN2 PIK3AP1 AZIN1 SAV1 EHD1 NAB1 KCNA3 SOD2 TAGAP ADORA2A-AS1 CCL20 ICAM1 TNFAIP8 NBN TAB2 GIMAP5 RIPK2 NLRP3 TRAF1 RND1 MAP3K4 HNRNPC NFKBIA MCOLN2 SAMSN1 LDLR PMAIP1 FNBP1 PIM3 FJX1 CLEC4E DCUN1D3	down	***
GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP	0.0000000	0.0000000	1.1421912	0.5754935	2.603648	173	HELLS KIF20A CDC45 PARPBP MCM10 BUB1B NEK2 POLQ PBK KIF18B NDC80 DEPDC1 BRCA1 TTK GINS1 RACGAP1 IQGAP3 GTSE1 ASPM STIL PLK1 NUF2 CDCA8 AURKB CENPA ESPL1 CDC6 TPX2 CCNB2 FIGNL1 RBBP8 UHRF1 MCM2 RAD54B MYBL2 PRC1 MUC20 SPDL1 MELK HMMR KIF23 CEP55 KNTC1 BUB1 AUNIP TOP2A AURKA KIF2C MCM7 CENPW RRM2 RAD54L KIF11 PASK CDC25C PSMG4 LIG1 MAD2L1 CKAP2L RAD51AP1 SPC24 DSCC1 PPIL1 KNSTRN CKS1B C12orf75 NUSAP1 ASF1B CDK1 CENPH BIRC5 C1orf112 GMNN NCAPG DNA2 NEIL3 FEN1 SPAG5 DIAPH3 CENPP UQCRFS1 ALDH7A1 KIF22 TK1 ESCO2 GINS2 SPAG1 FHL2 ATAD5 CDC20 CENPM CKAP2 MCM5 CD2BP2	up	***
GSE22886_NAIVE_CD8_TCELL_VS_DC_DN	0.0000000	0.0000000	1.0574636	-0.4867302	-2.598532	185	RAB11FIP1 SLC31A2 PNPLA6 STAC HHEX MNDA CAT RAPGEF2 RCOR1 EGR2 LMO2 CORO1C FLVCR2 HMGCR ARL8B SPG21 MAN2B1 ENTPD1 CLEC7A IFI30 ANXA5 ABHD6 LAMTOR3 TXN TUBB6 ATP6V1B2 CD58 CST3 ZMIZ1 FABP5 DUSP3 PPT1 DAB2 SLC7A8 CEBPA PLBD1 LY96 RIT1 VIM M6PR TM6SF1 CAPZA2 FCER1G GCA DSE HTT MPC1 HLA-DQA1 CRIM1 PI4K2A SNX3 VAMP3 CTSS PSEN1 PGD RAB31 ATP6V0B TBC1D12 SNX2 CD83 ZNF804A GRB2 SNX1 AP3B1 NDUFV2 PLCG2 SLC3A2 CD74 ATP6V1A GNG5 TMEM70 CCR1 NPTN CLASP2 RXRA TIAM1 SOAT1 DAPK1 GLUL GLRX2 CREG1 WDFY3 RNH1 FEZ2 CTSH FTL ATP1B1 PTGS1 CYP51A1 HLA-DRB1 MFSD1 GPR137B DLD RCBTB2 ZFYVE21	down	***
GNF2_BUB1	0.0000000	0.0000000	0.8753251	0.8175272	2.591573	26	FOXM1 KIF20A BUB1B NDC80 ASPM PLK1 CDCA8 AURKB ESPL1 CCNB2 MCM4 CDT1 RANBP1 MELK HMMR BUB1 KIF2C RRM2 CHAF1B CKS1B ASF1B GMNN SPAG5	up	***
GNF2_PECAM1	0.0000000	0.0000018	0.7195128	-0.6240106	-2.590470	45	FCN1 PECAM1 HSD17B11 NCF2 IGSF6 LILRB3 CD93 MCL1 PPT1 CASP1 PLBD1 CD302 FCER1G DUSP1 CMTM6 HCK CTSS TYROBP IFNGR1 CCR1 RGS2 CEBPD S100A4 THEMIS2 SH3BGRL3 ZFP36 MFSD1 TNFRSF1B PYCARD TMEM127 FGL2 RNF130	down	***
GNF2_RFC4	0.0000000	0.0000000	0.8870750	0.6722172	2.585026	57	FOXM1 MCM10 FANCI CENPF TIMELESS NDC80 TTK GINS1 ASPM CCNB2 MCM4 MCM2 TYMS NCAPD2 ZWINT CCT2 RANBP1 KNTC1 TOP2A MCM7 RAD54L KIF11 MCM3 LIG1 RAD51AP1 CKS1B CDK1 BIRC5 GMNN FEN1 SNRPE SSRP1 GINS2 SUPT16H MCM6 SNRPD1 MSH2 CCNA2 PRIM1 RFC5 SMC2 PAICS UBE2C	up	***
GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN	0.0000000	0.0000000	0.9101197	0.6262947	2.584453	81	TRIP13 CDC45 MCM10 BUB1B KIF18B NDC80 GINS1 RACGAP1 CDC6 CCNB2 MCM4 MCM2 TYMS CDC25A PRC1 HBB DTL ZWINT MELK CEP55 KIF15 BUB1 TOP2A KIF2C RRM2 KIF11 CHEK1 MAD2L1 RAD51AP1 DSCC1 CKS1B NUSAP1 CDK1 POLE2 BIRC5 GMNN NPM3 NCAPG FEN1 RNASEH2A SNRNP25 CCNE1 DLGAP5 TK1 GINS2 NUP85 CDC20 CENPM MCM6 MCM5	up	***
GNF2_FEN1	0.0000000	0.0000000	0.8513391	0.6753089	2.583563	54	FOXM1 FANCI CENPF KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 CCNB2 MCM4 MCM2 TYMS PRC1 DTL ZWINT HMMR PCCB TOP2A MCM7 KIF11 MCM3 DNAJC9 RAD51AP1 NUSAP1 CDK1 POLE2 GMNN FEN1 DLGAP5 DTYMK GINS2 MCM5 SNRPD1 MSH2 CCNA2 SHCBP1 RFC5	up	***
GNF2_ESPL1	0.0000000	0.0000000	0.8140358	0.7474244	2.582117	35	FOXM1 KIF20A BUB1B ASPM PLK1 CDCA8 AURKB CENPA ESPL1 TPX2 CCNB2 MCM4 NCAPD2 MELK HMMR MKI67 BUB1 TOP2A KIF2C RRM2 KIF11 MAD2L1 CKS1B ASF1B BIRC5 SPAG5 CDC20 CENPM MCM6 CCNA2 SMC2 CENPE PAICS UBE2C	up	***
GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_UP	0.0000000	0.0000000	1.1239150	0.5678323	2.578426	177	TRIP13 LINC00342 FOXM1 CDC45 FANCI TROAP CHEK2 BUB1B NEK2 CCNB1 TIMELESS FAM153B CLGN NDC80 PRIM2 BRCA1 PHGDH TTK GINS1 GTSE1 SLC27A2 KIF14 GMPS POLE STIL CENPA ESPL1 CDC6 TPX2 CCNB2 RBBP8 UMPS COCH XRCC2 CCNF ZWINT MELK HMMR EXO1 NUDT1 KIF23 CHAF1A RPL39L HLTF KNTC1 BUB1 FANCA TOP2A AURKA NUP155 KIF2C RRM2 KIF11 GPSM2 CDC25C LIG1 CHEK1 RAD51AP1 PKMYT1 BLM SKP2 CKS1B EFCAB11 CDKN2C TMEM106C CDK1 POLE2 DNA2 NUP205 SPAG5 FGFR1OP RNASEH2A NRGN NET1 FANCG CCNE1 TUBG1 DLGAP5 ALDH7A1 KIF22 SLC37A4 TK1 DTYMK ANP32E KIF20B	up	***
GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP	0.0000000	0.0000000	1.0175448	0.5862499	2.577299	131	TICRR MCM10 TROAP BUB1B CENPF POLQ UBE2T KIF18B TTF2 PIF1 BRCA1 TTK CDCA2 RACGAP1 E2F8 GTSE1 KIF14 ANLN POLE ASPM PLK1 CDCA8 ECT2 CDC6 TPX2 UHRF1 RAD54B PRC1 XRCC2 CCNF NCAPD2 PODXL2 KIF23 STAG3 MKI67 KIF15 KNTC1 TOP2A AKAP1 KIF11 FANCD2 LIG1 SARS2 CKAP2L BRIP1 INCENP NCAPG2 ANAPC5 HDGF CENPJ RFWD3 GMNN DNA2 SEC61G NEIL3 EZH2 NUP205 SPAG5 TACC3 MNS1 AARSD1 KIF22 CHTF18 ESCO2	up	***
GSE10325_BCELL_VS_MYELOID_DN	0.0000000	0.0000000	1.0175448	-0.4869350	-2.577015	172	SLC31A2 SASH1 HMOX1 ASGR1 OSBPL1A FBP1 PTPRE COQ2 LMO2 CCDC88A FCER1A RTN3 AQP9 MYD88 C5AR1 CLEC10A P2RY13 NCF2 IL1RN SLC11A1 IGSF6 PILRA LILRB3 TNFRSF8 SH2B3 HBEGF SLC7A7 NAAA CLEC7A ANXA5 SIRPA CD93 SRGN TCF7L2 CYBRD1 CFD PTGIR KIAA0513 CASP1 KLF4 PLAUR CPVL DRAM1 CEBPA PLBD1 COTL1 KCNMB1 CD302 TM6SF1 DUSP1 HEXB OASL KCTD12 HK3 CSTA LGALS2 FOS TNFSF13 RIN2 GALC LGALS3 CCR1 FCGRT RGS2 RXRA ICAM1 CEBPD CDKN1C NLRP3 ALDH2 MEGF9 S100A4 DAPK1	down	***
GSE29618_PDC_VS_MDC_DAY7_FLU_VACCINE_DN	0.0000000	0.0000000	1.0276699	-0.4839901	-2.573621	176	FCN1 IL1B MNDA PTP4A2 PID1 FYN LY86 CLEC10A P2RY13 NCF2 CD1C IL1RN AGTPBP1 IGSF6 PILRA FGR ANXA1 ATP2B1 ASAP1 CD33 LMNA ASAH1 ENTPD1 CLEC7A CSRP1 ITGA5 IFI30 PICALM ANXA5 SIRPA RGCC TMEM123 CST3 EPB41L2 ARRB1 CASP1 LIMS1 YBX3 KLF11 PLBD1 COTL1 ITGAX ID2 EVI2A HCK EMP3 PRCP RBPJ SGK1 SEC14L1 C2CD2 RAB31 KCTD12 RHOG CSTA PTGER4 PSTPIP2 GMFG SERPINB6 CST7 PPM1F ATG3 CD1D PDLIM1 CD86 APLP2 LGALS3 DOK2 MFNG IL18 SLC35D2 RTN1 SEMA4A CEBPD NLRP3 MEGF9 S100A4 ICAM3 CD1E LYST RNH1 CNN2 CACNA2D3 EGR1 CTSH CDKN1B AOAH TUBA1A ATP1B1 PTGS1	down	***
GNF2_TNFSF10	0.0000002	0.0000093	0.6901325	-0.7080512	-2.564815	26	MNDA C5AR1 P2RY13 NCF2 IGSF6 PILRA DPEP2 CLEC7A SPI1 EVI2B SDCBP LY96 HCK CCR1 RGS2 ARRB2 UBE2D1 S100A4	down	***
GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_DN	0.0000000	0.0000000	1.0175448	-0.4791976	-2.563938	186	SASH1 ZC3H12C IL1B FABP4 NUP54 RAPGEF2 BMP2 EGR2 CCRL2 CAV1 CITED2 CDC42EP2 SLC15A3 STX11 BCL2A1 IL1RN IL23A IER2 CCNL1 HBEGF SBDS SDE2 BTG2 MAP3K8 KLF6 SLAIN2 NDEL1 SRGN MCL1 TIPARP IL10 CSRNP1 TLE4 RAB12 PLAUR COQ10B ID3 ZFAND5 KLF7 ATF3 C9orf72 ID2 CCL4 PNRC1 DUSP1 PLEK SPRYD7 MAFF USP16 RASGEF1B BTG1 RBM39 GPBP1 ETF1 SLC25A25 ETV3 ARL5B MTMR14 KCTD12 HSPA1B DUSP8 PTGER4 CD83 OSM MALT1 REL FOS CDK17 TREX1 EHD1 TGIF1 DUSP5 ZBTB11 GPR84 SOD2 GTF2B RNF2 ICAM1 ABL2 IER5 RIPK2 FBXO30 PTCH1 TRAF1 JMJD1C TNFSF9 NABP1 DNAJA2 RABGEF1 PIM3 HERPUD1 SERPINE1 ZNF800 CLEC4E OSGIN2 SLC38A2	down	***
HAHTOLA_MYCOSIS_FUNGOIDES_CD4_UP	0.0000000	0.0000010	0.7337620	-0.5942012	-2.563239	53	CXCL3 EREG ABHD5 IL1B PRKAR1A MANBA FUCA1 FAM49A TRIB1 MCTP1 HBEGF GM2A BTG2 KLF6 RHOB KLF4 PLAUR CCL3 CDKN1A CXCL2 ATF3 CCL4 ACTR2 PPP1R15A GLIPR1 CHPT1 SOD2 KYNU ETS2 MS4A4A RIPK2 NLRP3 GLUL EMC3 EGR1	down	***
NAGASHIMA_NRG1_SIGNALING_UP	0.0000000	0.0000000	0.9759947	-0.4924633	-2.557983	160	WEE1 SOWAHC GATA2 MIR22HG SIK1 FOSL1 NEDD9 TRIB1 CASP9 IER2 CCNL1 AVPI1 CLCF1 TRA2B SEMA3B HBEGF EIF5 MAP3K8 KLF10 KLF6 NR4A1 NDEL1 MCL1 ZNF365 TUBB6 TIPARP MAP2K3 PLAUR ID3 ZFAND5 PER2 ATF3 ARC PER1 DUSP1 HES1 MAFF AKIRIN1 TGFB2 STK24 SRF AREG SGK1 AQP3 SERPINB8 JUN JUNB DUSP8 PPP1R15A FERMT2 IFRD1 SPATA2L REL HOMER1 TNFRSF10B FOS KLF2 EPPK1 FOSB JMJD6 DUSP5 IRS2 GATA6 RGS2 PLEKHO2 ETS2 GEM PDLIM5 IER5 CDC42EP3 CXCR4 TOB2 PSME4 EPHA2 EDN1 LDLR PMAIP1 SPHK1 EGR1 NR4A2 ZYX ZFP36 YRDC DNAJB1 BCL10 TES NFIL3 NR4A3 ZNF331 KBTBD2 DUSP2	down	***
GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP	0.0000000	0.0000000	0.9865463	-0.4859121	-2.550282	165	PHACTR1 TUBB1 SIK1 INSIG1 EGR2 OTUD1 BACH1 C5AR1 YPEL5 ARL8B STX11 PPM1D RBM7 SH2B3 B3GNT5 HBEGF TACC1 TM2D3 CHMP1B BTG2 NR4A1 TRAF6 NFE2L2 UBE2D3 TIPARP RHOB ZMIZ1 CSRNP1 CDADC1 MTMR6 ITPRIP ATP11A-AS1 COQ10B ZFAND5 CDKN1A CXCL2 ATF3 DUSP1 ARL4A SMNDC1 RASGEF1B SIAH1 USP25 ETF1 HCAR3 DCP1A GZF1 TMOD1 AREG SGK1 SOCS3 RAB8B UTRN ETV3 ARL5B JUNB PTGER4 MCM9 BAG5 CD83 GPR183 N4BP3 OSM FSD1L REL FOS PTP4A1 YTHDF3 FOSB CHORDC1 ABHD13 PDE12 CRY1 GNA13 RGS2 CLEC2B CCL20 NR2E3 RNF138 DCTN4 CXCR4 RIPK2 MEX3C CUL3 MAFK C20orf203 DNAJB9 SAMSN1 CNTNAP3B	down	***
AMIT_EGF_RESPONSE_40_HELA	0.0000001	0.0000063	0.6901325	-0.6299658	-2.550003	39	IER2 CCNL1 BTG2 KLF6 NR4A1 ATF3 DUSP1 HES1 CDKN2AIP PIAS1 IL6 SGK1 RNF141 JUN JUNB PPP1R15A MBNL2 ATL2 PALMD KLF2 DUSP5 MBNL1 LDLR EGR1 ZFP36 PTGS2 DUSP2 CBX4 ID1	down	***
GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_DN	0.0000000	0.0000000	0.9969862	-0.4803919	-2.549840	180	ACP5 SASH1 OSBPL1A MNDA CAT ADCY9 ENG HSD17B11 LMO2 BACH1 SLC15A3 P2RY13 TBC1D2 MKNK1 MANBA LAMP1 AGPAT4 SLC11A1 EPB41L3 FAM49A CD36 DPEP2 ARHGAP10 PLA2G7 MCTP1 CD33 ASAH1 RNASE1 ADIPOR1 STOM LAIR1 TFEC IL10 ARRB1 DUSP3 PPT1 ITM2B PXDC1 KLF11 DAB2 ATP6V1D LY96 RIT1 CDKN1A TM6SF1 PLEK GCA DSE IL7R TDRD7 HEXB HCK NINJ1 TMEM9B CYB5R1 SERPINB8 C2CD2 C1QA KCTD12 CTSZ ATP6V0B MOB1A TNFSF13 CD74 RIN2 BAZ2B CD86 LGALS3 SERINC3 CLEC2B BMP2K IL18 CALHM2 SEMA4A CEBPD MEGF9 METTL7A CTSC PTEN DNAJB9 MMD CREG1 EMC3 EHD4	down	***
BURTON_ADIPOGENESIS_3	0.0000000	0.0000000	0.8986712	0.6140338	2.547653	84	HELLS KIF20A CDC45 MCM10 CCNB1 BRCA1 CDCA7 TTK RACGAP1 E2F8 PLK1 CDCA8 CDC6 CCNB2 FIGNL1 MCM4 MCM2 TYMS PRC1 CCNF DTL MKI67 BUB1 TOP2A AURKA KIF2C RRM2 KIF11 MCM3 TOPBP1 RAD51AP1 INCENP NUSAP1 ASF1B OSMR CDK1 BIRC5 FEN1 EZH2 DNMT1 ILF2 DLGAP5 TACC3 KIF22 TK1 DTYMK NUP85 CDC7 CENPK CDC20	up	***
GNF2_CARD15	0.0000000	0.0000008	0.7477397	-0.5874212	-2.546984	56	FCN1 PECAM1 MNDA STX11 NCF2 IGSF6 PILRA LILRB3 CD33 SLC7A7 CD93 MCL1 PPT1 CASP1 BST1 CPVL PLBD1 COTL1 CD302 DUSP1 HCK CTSS HK3 TYROBP FOS CD1D CD86 CCR1 RGS2	down	***
GSE29618_PDC_VS_MDC_DN	0.0000000	0.0000000	1.0073180	-0.4785731	-2.544816	176	FCN1 MNDA PTP4A2 PID1 LY86 LMO2 CLEC10A P2RY13 STX11 BCL2A1 NCF2 CD1C IL1RN TRIB1 PILRA FGR ANXA1 ATP2B1 SPG21 ASAP1 CD33 LMNA ENTPD1 CLEC7A IFI30 PICALM ANXA5 STOM CD93 SPI1 CST3 TIPARP RHOB FBXL5 PTPN12 ARRB1 PPT1 CASP1 YBX3 KLF11 PLBD1 ITPK1 TMBIM1 COTL1 ITGAX PTPRC ID2 ARHGDIB HCK EMP3 RBPJ YBX1 SGK1 C2CD2 PHF10 RAB31 JUNB RHOG CSTA PTGER4 PSTPIP2 GMFG SERPINB6 LGALS2 NDST1 SLC25A24 ATG3 CD1D SERPINB1 PDLIM1 CD86 LGALS3 RTN1 CEBPD MEGF9 S100A4 ICAM3 CD1E IQGAP1 CREG1 RNH1 CNN2	down	***
GNF2_CD33	0.0000001	0.0000044	0.7049757	-0.6185805	-2.540301	42	FCN1 STX11 LILRB3 IER2 CD33 SLC7A7 IFI30 CD93 PPT1 CASP1 BST1 CPVL PLBD1 CD302 DUSP1 CTSS HK3 TYROBP LGALS2 FOS CD1D RGS2 NLRP3	down	***
VECCHI_GASTRIC_CANCER_EARLY_UP	0.0000000	0.0000000	1.4172759	0.5223844	2.540116	379	ATP10B TRIP13 MUC13 MYEOV FOXM1 CEP72 KIF20A CDH17 PARPBP MCM10 FANCI TFAP2A PDCD6 BUB1B NEK2 CCNB1 CENPF UBE2T SEMA4B PBK KIF18B THOC3 NDC80 GUCY2C DEPDC1 BRCA1 DEPDC1B CDCA7 C12orf66 LCN2 TTK GINS1 CDCA2 RACGAP1 E2F8 GTSE1 KIF14 ANLN STK31 ILDR1 PMS2P5 SPP1 ASPM COL7A1 NUF2 EFNA4 CENPA PTTG1 ECT2 CDC6 TPX2 CCNB2 FIGNL1 H19 UHRF1 MCM4 STRIP2 MCM2 RAD54B ZNF117 MYBL2 FERMT1 PRC1 EIF3B DTL MARVELD3 XPO5 GINS4 ZWINT SPDL1 WDR90 NME1 RANBP1 RUVBL2 ITGA2 CLDN1 MELK HMMR CEP55 KCNN4 LAMC2 MKI67 KIF15 BUB1 MSX2 TOP2A PUS7 AURKA NUP155 MCM7 CENPW RRM2 CDCA5 HOXC6 SLC4A11 FANCD2 GPSM2 WDR72 CHEK1 PDZK1IP1 ASS1 MAD2L1 PFKP RAD51AP1 DSCC1 BRIP1 RAD18 SKP2 CKS1B NCAPG2 NUSAP1 KRT18 CDK1 CDK12 KCNE3 CENPH BIRC5 CCT3 NCAPG FEN1 CDH3 EZH2 TNRC18 LAPTM4B EFTUD2 RP9 CCNE1 PABPC1L DPP3 DLGAP5 CTSV GSS EPHB2 TK1 ESCO2 IL15RA GINS2 ANP32E MMP7 CENPK PROX1 TIMM13 CDC20 CENPM HMGA1 POP7 CXCL1 WRNIP1 PRMT1 CKAP2 DHX8 XRCC4 MCM5 SNRPD1 AATF ZDHHC11 GAD1 TMEM45B ATAD2 CCNA2 SMARCA4 RBM42 PRR11 TMC5 ABHD10 WDR77 BMS1 RNF123 RARRES1 AIFM2 TMED9 TBCB RBM19 LIF RPN1 PFDN4 PCBD1 CDC25B UBE2C PDP1 SFXN4 MSRB1 ENO1 RASGEF1A E2F7 RRS1 ZNF367 NUP93 TRUB2 ASCL2 C12orf10 ARHGAP8 PMEPA1 CAMK2N1 KLK10 ZNF511 MRTO4 SPIDR MRPS16 NSUN5 SHQ1	up	***
GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_UP	0.0000000	0.0000000	0.9759947	-0.4834884	-2.537561	165	CD300LF HMOX1 CXCL16 PPARG MNDA CYP27A1 THBD OSCAR TMEM170B AATK LMO2 CORO1C ALAS1 NCF2 SLC11A1 EPB41L3 IGSF6 PILRA LILRB3 HBEGF LIFR ASAH1 GM2A IFI30 ANXA5 ANPEP SIRPA SLC25A37 GRN TFEC ARHGEF2 ATP6V1B2 UNC45B MSR1 MPEG1 PTAFR VRK2 TPP1 CLIC4 LY96 HPSE GCA DSE LIN7A HCK HCAR3 RAB31 CTSZ ATP6V0B GSTO1 PSTPIP2 LGALS2 ZBED5 NOP10 ALDH3B1 IRF5 TCF4 DOK3 FPR2 TSC22D1 CD86 GNB4 LGALS3 BRI3 FCGRT KYNU SLC8A1-AS1 SLC43A2 GLUL BCAT1 TMCC3 NRP2 DOCK4 CREG1 WDFY3 DMXL2 CSF2RB LHFPL2 AOAH FTL FPR1 WDR41 C6orf62 MFSD1 DAPP1	down	***
GNF2_SMC4L1	0.0000000	0.0000000	0.8753251	0.6161906	2.534712	80	FOXM1 FANCI BUB1B CENPF KIF18B NDC80 TTK GINS1 RACGAP1 E2F8 ASPM CDCA8 CCNB2 MCM4 MCM2 TYMS PRC1 DTL ZWINT HMMR PCCB TOP2A AURKA CBX3 MCM7 KIF11 MCM3 DNAJC9 RAD51AP1 NUSAP1 CDK1 POLE2 GMNN FEN1 DLGAP5 SSRP1 DTYMK GINS2 ANP32E SUPT16H CDC20 CKAP2 MCM5 SNRPD1 SRSF1 MSH2 CCNA2 PRIM1 SHCBP1 ZWILCH	up	***
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP	0.0000000	0.0000000	1.5498781	0.5121418	2.534107	491	TRIP13 DDX11 FOXM1 HELLS KIF20A HJURP AK4 CEP89 CDC45 TICRR PARPBP MCM10 FANCI TROAP CHEK2 BUB1B NUP107 SLFN13 NEK2 CCNB1 CCDC34 CENPF TIMELESS UBE2T PBK KIF18B TTF2 NDC80 PRIM2 DEPDC1 PIF1 DEPDC1B CDCA7 TTK GINS1 CDCA2 RACGAP1 IQGAP3 GTSE1 TRAIP POLE ASPM STIL ANKRD24 CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 MCM2 TYMS UMPS MYBL2 PMS2 PRC1 XRCC2 ORC1 CCNF DLGAP1 DTL MCM8 MIS18A NCAPD2 CDT1 SPDL1 LSM5 TAMM41 LDHB HAUS5 WDR62 TTLL4 MELK HMMR EXO1 NLE1 KIF23 CEP55 MKI67 KNTC1 PAFAH1B3 BUB1 FANCA CCDC77 AUNIP TOP2A CENPL AURKA EME1 POLA2 SLC29A2 POLD2 KIF2C MCM7 MAD1L1 E2F2 CENPW CLSPN RRM2 MMS22L CDCA5 WDHD1 RAD54L ERAL1 KIF11 PASK FANCD2 MCM3 CHAF1B LMNB1 CDC25C LIG1 CHEK1 C7orf50 DNAJC9 THYN1 MAD2L1 CKAP2L RAD51AP1 DCTPP1 XRCC1 SPC24 DSCC1 PKMYT1 RAD18 BLM SLC25A10 SKP2 PSRC1 INCENP KNSTRN CKS1B NCAPG2 CDKN2C NUSAP1 ASF1B CDK1 POLE2 CCDC61 SERTAD4 CENPH BIRC5 C1orf112 TESC GMNN E2F1 UNG NCAPG DNA2 FEN1 EZH2 SPAG5 POC1B SMO RECQL4 CENPP PA2G4 RANGAP1 NET1 DNMT1 LGR5 CCNE1 CEP192 AKR1E2 DLGAP5 NPTXR NMRAL1 TACC3 LMNB2 MNS1 OSBPL3 PTGES2 KIF22 HIRA DUSP12 TK1 CHTF18 CASP7 CENPQ ESCO2 MLEC GINS2 GEMIN5 ANP32E KIF20B NOC2L POLD1 NUP85 SLC1A3 ATAD5 CDC7 RAD50 CENPK SASS6 GEMIN6 PTN CKAP5 L3MBTL2 CDC20 PALB2 CENPM ANKRD6 ERBB3 AAAS GPATCH4 RPA1 MCM6 LPCAT4 CENPT CKAP2 MCM5 ZRANB3 HAUS6 LANCL2 RCC1 HAUS4 LSM4 NT5DC2 ATAD2 CEP152 DDAH1 SUV39H2 CCNA2 PRIM1 PRR11 SHCBP1 RFC5 BLVRB RAD51 SNX7 ZWILCH FBN2 ARHGAP11A RHOT2 WDR76 MXD3 ARHGEF39 SMC2 TONSL CENPE C1orf159 SEPHS1 CDC25B UBE2C TAF4 PTOV1 NUP210 E2F7 ZNF367 C4orf46 SART3 C12orf10 FBXL18 NCAPH GEMIN2 CD38 KIAA0586 TPM1	up	***
GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_DN	0.0000000	0.0000000	0.9969862	-0.4811146	-2.533310	170	SLC31A2 HMOX1 FCN1 MCOLN1 OSBPL1A MNDA CYP27A1 CAT LIPA FIG4 CCRL2 SAMHD1 CITED2 P2RY13 MARCO MANBA NCF2 SLC11A1 EPB41L3 PILRA FGR MAN2B1 SLC7A7 IFI30 ABCG1 KLF6 STOM LAIR1 RB1 SPRY2 EVI2B GPA33 CPVL RUNX1T1 DAB2 DRAM1 THBS1 LY96 ERP44 CDKN1A ITGAX SELL CCL4 CD302 FCER1G FKBP15 GLB1 HCK KANK1 VAMP3 PGD C1QA KCTD12 LTBP2 PSTPIP2 FOS EPPK1 RIN2 SORT1 GSAP CD1D APLP2 CCR1 FCGRT KYNU CLEC2B RXRA OPN3 MS4A4A GIMAP5 SLC2A9 THEMIS2 LPAR6 RNH1 MAN1C1 TMEM50A CLEC4E AOAH S100A8 KBTBD11	down	***
GSE29618_BCELL_VS_MDC_DN	0.0000000	0.0000000	0.9969862	-0.4773364	-2.530142	181	RAB11FIP1 CD101 FBP1 CAT DPYSL2 LMO2 CCDC88A FCER1A ST3GAL6 CLEC10A PRKAR1A CD1C TRIB1 EIF4A1 ASAP1 CD33 LMNA IFI30 PICALM ANXA5 LCP1 STOM IL18R1 CD93 GRN TXN CST3 TIPARP ARRB1 DUSP3 CASP1 KLF4 DAB2 TPP1 PLBD1 ITPK1 COTL1 ITGAX VIM AXL ID2 CAPZA2 CPT1A GNAQ GNAI2 CALM2 PRCP RBPJ RAB31 KCTD12 RHOG RCAN1 GSTO1 GLIPR1 PSTPIP2 GMFG CAP1 GRSF1 ATG3 MYL12A PEA15 CD1D GNG5 TOB1 ETS2 SELPLG IL18 ARPC2 FKBP1A WDR1 RTN1 SEMA4A RTN4 CEBPD ACTB S100A4 CD1E ARPC5	down	***
FARMER_BREAST_CANCER_CLUSTER_2	0.0000000	0.0000000	0.8140358	0.7623394	2.528885	31	KIF20A BUB1B NEK2 NDC80 ASPM CENPA PTTG1 TPX2 CCNB2 MCM4 RAD54B PRC1 MELK CEP55 KIF15 MRPL15 BUB1 PRKDC KIF11 MAD2L1 NUSAP1 ESRP1 NCAPG	up	***
GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP	0.0000000	0.0000000	1.0672100	0.5589115	2.527940	171	TRIP13 HJURP CDC45 FANCI ELOVL6 CCNB1 CENPF PTPRN2 GINS1 SNF8 CDCA8 AURKB CENPA PTTG1 TPX2 CCNB2 RBBP8 MCM4 MCM2 TYMS MYBL2 PRC1 DTL SHMT2 ZWINT CDT1 AGK MELK EXO1 CEP55 RPL39L EMC9 KIF15 KNTC1 BUB1 AURKA KLHL25 KIF2C MCM7 RRM2 WDHD1 KIF11 LMNB1 LIG1 PDZK1IP1 MRPS11 PTGDR2 BLM IDH2 PSRC1 CKS1B NCAPG2 PPIL2 NUSAP1 TMEM106C CBX5 BIRC5 C1orf112 GMNN FEN1 EZH2 SPAG5 MRPS12 RALGPS1 RNASEH2A FANCG UBFD1 DPP3 DLGAP5 KIF22 MRPL11 ZNF544 TK1 PKP4 IGHM CCDC51 NTN3 COG4 COX10 CDC7 CDC20 CENPM PPCDC LANCL2 RCC1 ATAD2 CCNA2 RAD51 TPGS2 ZWILCH WDR76 UQCRQ CENPE GGCX CDC25B UBE2C ZMYND10 RAD1	up	***
ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR	0.0000000	0.0000000	0.8634154	0.6161347	2.525005	78	TRIP13 KIF20A PARPBP NEK2 TIMELESS UBE2T BRCA1 TTK RACGAP1 E2F8 CDCA8 CENPA UHRF1 MCM2 MYBL2 DTL CDT1 RANBP1 EXO1 CEP55 KNTC1 MCM7 POC1A CDCA5 WDHD1 RAD54L KIF11 MCM3 CHAF1B LMNB1 TOPBP1 DNAJC9 MAD2L1 DCTPP1 NUSAP1 GMNN E2F1 EZH2 DLGAP5 KIF22 DTYMK GINS2 SAP30 MAGOHB CENPK MCM6 MCM5 GINS3 CCNA2 RFC5 RAD51	up	***
GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	0.0000000	0.0000000	0.9969862	-0.4794697	-2.524649	170	ACP5 CD52 HVCN1 DPYSL2 FIG4 FYN CCDC88A MANBA CD9 IL23A TXNIP CD36 DPEP2 CORO6 GM2A CSGALNACT2 TTYH2 RNASE1 LAIR1 C1orf162 RGCC NFE2L2 SORBS3 EVI2B CYBRD1 AHNAK SDCBP RRM2B ID3 TPP1 PLBD1 TMBIM1 PDE3B LBH EVI2A CRIM1 HGSNAT NCKAP1L PRCP PDK4 SLC8A1 ELF1 CTSS RAB8B UTRN AQP3 MITF STAT4 GSTO1 GCNT4 SNRK PELI1 TIMP2 LGALS3 TOB1 DECR1 PRDM8 CALHM2 RTN1 ARRB2 ACAP2 NLRP3 METTL7A CD3G CREG1 LYZ ARRDC2 SPPL2A SH3BGRL3 CLEC4E C5 ZYX RAB37 CD109 NFAM1 PDE7B RCSD1 RCBTB2 PPFIBP1 UEVLD LRP1 CD4 FAM111A ANKRD44 GSN	down	***
GSE34156_TLR1_TLR2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP	0.0000000	0.0000000	0.9545416	-0.4816921	-2.523468	163	CXCL3 CD300LF HMOX1 CXCL16 PPARG CYP27A1 PTPRE OSCAR LMO2 CCDC88A CORO1C NCF2 SLC11A1 EPB41L3 IGSF6 PILRA LILRB3 ASAH1 GM2A IFI30 ANXA5 ANPEP SIRPA SLC25A37 CD93 GRN TFEC ATP6V1B2 MSR1 DUSP3 MEFV MPEG1 LIMS1 PTAFR VRK2 CLIC4 CTSD KCNMB1 HPSE TLR4 DSE GPR157 ACTR2 HCK LACC1 HCAR3 KLRB1 HPGDS RAB31 CTSZ TYROBP IFNGR1 PSTPIP2 PRKCE ATP13A3 LGALS2 CD151 RIN2 IRF5 CHIA DOK3 FPR2 CD86 GNB4 LGALS3 BRI3 CCR1 FCGRT KYNU PLEKHO2 PITPNA RAB5A ACTB GLUL BCAT1 TMCC3 NRP2 DOCK4 NABP1 CREG1 WDFY3 RAB2A DMXL2 CSF2RB DUSP6 CLEC4E LHFPL2 FTL	down	***
GNF2_SPI1	0.0000002	0.0000094	0.6901325	-0.6755769	-2.523019	30	MNDA BACH1 AQP9 C5AR1 P2RY13 NCF2 FRAT1 IGSF6 PILRA CLEC7A SPI1 VASP LY96 GCA HCK	down	***
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN	0.0000000	0.0000000	1.0768682	0.5573423	2.519843	174	FOXM1 KIF20A CDC45 MCM10 BDH1 FANCI ELOVL6 BUB1B CCNB1 POLQ APOLD1 GBAP1 PBK TTF2 TTK HILPDA TRAIP ASPM STIL CDCA8 CENPA PTTG1 ESPL1 CDC6 CCNB2 RBBP8 MCM2 TYMS CDC25A UMPS DTL MIS18A ZWINT MYL6B NME1 HMMR CISD1 CEP55 MKI67 KIF15 KIF3B BUB1 LGMN TOP2A AURKA POLA2 KIF2C MCM7 RRM2 RAD54L KIF11 AIMP2 CHEK1 RAD51AP1 DCTPP1 TST CKS1B NUSAP1 TMEM106C POLE2 BIRC5 GMNN NCAPG NEIL3 FEN1 SPAG5 POLR2H UBFD1 DPP3 TUBG1 DLGAP5 FAH LMNB2 RAD51D TK1 DTYMK MLEC GINS2 CCDC51 SAP30 PFAS CKAP5 CDC20 CENPM ZNF248 PPCDC MCM5	up	***
WHITFIELD_CELL_CYCLE_LITERATURE	0.0000000	0.0000000	0.8140358	0.6890060	2.514231	44	KIF20A CDC45 BUB1B CCNB1 CENPF BRCA1 RACGAP1 PLK1 CENPA CDC6 CCNB2 MCM2 TYMS CDC25A CCNF BUB1 TOP2A AURKA RRM2 CDC25C CDKN2C CDK1 BIRC5 E2F1 CCNE1 CDC20 MCM6 MSH2 CCNA2	up	***
GSE22886_NAIVE_TCELL_VS_DC_DN	0.0000000	0.0000000	0.9865463	-0.4712515	-2.513461	183	EPAS1 SLC31A2 KMO STAC PTPRE LIPA RCOR1 CCDC88A CORO1C FLVCR2 EPB41L3 IGSF6 CD36 PLA2G7 SPG21 MAN2B1 ASAP1 ADAM17 ENTPD1 ANPEP ABHD6 SIRPA NFE2L2 ZMIZ1 PPT1 SDCBP DAB2 GAA SLC7A8 CEBPA PLBD1 LY96 ATG7 RIT1 VIM M6PR PLEKHB2 GCA DSE SLC6A6 TM9SF2 DEGS1 CRIM1 PI4K2A GLB1 HGSNAT SNX3 VAMP3 BCAR3 PGD SLCO2B1 C1QA MTMR14 MITF KCTD12 CTSZ ATP6V0B IFNGR1 TBC1D12 ZNF804A SNX1 AP3B1 NDUFV2 PEA15 KYNU ZNF267 VASH1 LRP12 CYB5R4 ALDH2 DAPK1 STAM2 GLRX2 ARPC5 DOCK4 CREG1 WDFY3 EHD4 RNH1 FEZ2 ZFYVE26 LHFPL2 TREM2 FTL ATP1B1 PTGS1 CYP51A1 MFSD1 GPR137B MPV17	down	***
GNF2_MKI67	0.0000000	0.0000000	0.8140358	0.7823286	2.511171	27	FOXM1 KIF20A CENPF KIF18B ASPM CENPA ESPL1 TPX2 NCAPD2 ZWINT MELK HMMR MKI67 TOP2A AURKA RRM2 KIF11 NUSAP1 CDK1 BIRC5 NCAPG	up	***
GNF2_CD1D	0.0000002	0.0000082	0.6901325	-0.6425331	-2.500637	36	FCN1 STX11 IGSF6 LILRB3 CD33 SLC7A7 CASP1 CPVL PLBD1 COTL1 CD302 DUSP1 HCK CTSS HK3 TYROBP FOS CD1D CD86 RGS2	down	***
NIKOLSKY_BREAST_CANCER_12Q13_Q21_AMPLICON	0.0000000	0.0000001	0.8012156	0.7099040	2.499466	38	TSPAN8 MDM1 NUP107 CPSF6 AVIL RAB3IP TSFM PTPRR C12orf66 METTL1 CDK4 YEATS4 CYP27B1 SLC35E3 KCNMB4 CAND1 XPOT CCT2 FRS2 MDM2 DYRK2 CTDSP2 TSPAN31 LGR5 CNOT2 OS9	up	***
GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN	0.0000000	0.0000000	0.9759947	-0.4720198	-2.498177	169	SLC31A2 CD300LF SWAP70 CXCL16 MNDA CYP27A1 PTPRE TMEM170B LMO2 CORO1C ALAS1 NCF2 SLC11A1 EPB41L3 MOB1B IGSF6 PILRA LILRB3 ASAH1 GM2A EMILIN2 IFI30 ANXA5 ANPEP ZNF697 SIRPA SLC25A37 GRN TFEC ARHGEF2 ATP6V1B2 UNC45B RAB12 MPEG1 MED11 PTAFR TPP1 CLIC4 LY96 HPSE CAPZA2 GCA DSE GPR157 LIN7A HCK CD8B PGD RAB31 KCTD12 VPS26A TMEM251 PSTPIP2 LGALS2 ZBED5 NOP10 ALDH3B1 IRF5 TIMP2 TCF4 DOK3 FPR2 TSC22D1 CD86 GNB4 LGALS3 BRI3 KYNU SLC8A1-AS1 PITPNA GLUL BCAT1 SIGLEC9 NRP2 DOCK4 CREG1 WDFY3 DMXL2 CSF2RB LHFPL2 AOAH FTL	down	***
GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN	0.0000000	0.0000000	0.9653278	-0.4785608	-2.498164	158	CXCL3 ACVRL1 CXCL16 SGK3 PPARG AATK LMO2 CORO1C NCF2 EPB41L3 IGSF6 PILRA LILRB3 ASAH1 GM2A EMILIN2 IFI30 ANXA5 ANPEP ZNF697 SIRPA SLC25A37 CD93 GRN TFEC ATP6V1B2 PTPN12 MSR1 CYBRD1 MPEG1 LIMS1 PTAFR CLIC4 CTSD HPSE DSE GPR157 HCK LACC1 HCAR3 KLRB1 KIF13A PGD FOXP1-IT1 SLC35E4 RAB31 CTSZ TYROBP PSTPIP2 ATP13A3 LGALS2 ACSL1 CD151 RIN2 IRF5 DOK3 FPR2 CD86 EWSR1 GNB4 LGALS3 BRI3 CCR1 KYNU PLEKHO2 SLC8A1-AS1 PITPNA SLC43A2 ACTB HAVCR2 GLUL BCAT1 SIGLEC9 TMCC3 NRP2 CREG1 ANO6 DMXL2 CSF2RB AQP5 LHFPL2 FTL	down	***
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP	0.0000000	0.0000000	1.0175448	0.5560925	2.495707	158	TRIP13 KIF20A CDC45 MCM10 FANCI ELOVL6 BUB1B NEK2 CCNB1 DNAJC12 CENPF PBK KIF18B NDC80 SORD BRCA1 TTK GINS1 RACGAP1 E2F8 ASPM AURKB CENPA ECT2 ESPL1 CDC6 SFXN1 TPX2 CCNB2 MCM4 MCM2 TYMS PRC1 HBB SHMT2 ZWINT LSM5 RANBP1 MELK HMMR NUDT1 CEP55 KIF15 BUB1 TOP2A AURKA KIF2C MPO RRM2 TFR2 KIF11 CHEK1 MAD2L1 RAD51AP1 DSCC1 TST IDH2 CKS1B NUSAP1 CDK1 POLE2 BIRC5 GMNN NPM3 NCAPG SLC25A13 FEN1 EZH2 SPAG5 ITGA2B RNASEH2A SNRNP25 CCNE1 DLGAP5 TK1 GINS2 NUP85 CDC7 CDC20 CENPM LRRC59	up	***
WINNEPENNINCKX_MELANOMA_METASTASIS_UP	0.0000000	0.0000000	1.0276699	0.5597129	2.493863	147	CDC45 PARPBP NEK2 CCNB1 CENPF TIMELESS UBE2T KIF18B NDC80 PHF14 PRIM2 RACGAP1 ANLN GMPS ASPM NUF2 CDCA8 CENPA PTTG1 ECT2 CDC6 CCNB2 UHRF1 MCM4 TYMS PRC1 ZWINT NME1 RANBP1 MELK EXO1 CEP55 DCBLD2 KNTC1 BUB1 TOP2A CCT5 AURKA KIF2C RSRC1 RRM2 CDCA5 RAD54L KIF11 KDELR2 CHEK1 DSCC1 ZNF587 KNSTRN CKS1B NCAPG2 PLOD2 CDK1 BIRC5 EEPD1 GMNN NCAPG NEIL3 SPAG5 UBFD1 DLGAP5 TK1 DTYMK GINS2 RBM33 CCT7 GEMIN6	up	***
GNF2_FOS	0.0000002	0.0000103	0.6901325	-0.6593366	-2.492242	33	FCN1 STX11 IER2 CD33 KLF4 CPVL TPP1 PLBD1 CD302 DUSP1 CTSS HK3 LGALS2 FOS CD1D NLRP3 SCPEP1 NFKBIA DUSP6 ZFP36 MFSD1 CPPED1 PYCARD CAPG FGL2 NAIP RNF130	down	***
GNF2_CENPE	0.0000000	0.0000004	0.7614608	0.7101751	2.488973	37	FOXM1 CENPF KIF18B NDC80 ASPM CDCA8 AURKB ESPL1 CCNB2 TYMS MYBL2 PRC1 CCNF ZWINT HMMR MKI67 BUB1 AURKA RRM2 KIF11 CKS1B NUSAP1 CDK1 BIRC5 DLGAP5 CDC20 CCNA2 PRIM1 SHCBP1 SMC2 CENPE UBE2C	up	***
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN	0.0000000	0.0000000	1.0476265	0.5478664	2.485986	176	TRIP13 FOXM1 KIF20A HJURP MCM10 BDH1 FANCI BUB1B CCNB1 CENPF TIMELESS TUBB2B CDK4 RACGAP1 ASPM AURKB CENPA ESPL1 CDC6 TPX2 CCNB2 RBBP8 MCM4 MCM2 TYMS DTL MIS18A ZWINT MYL6B NME1 MELK HMMR NUDT1 KIF23 CEP55 MKI67 EMC9 MRPL15 TP53BP1 PCCB TOP2A AURKA APOL1 NDUFS2 SMARCAL1 MCM7 RRM2 KIF11 GNPDA1 BLM COMMD4 CKS1B NCAPG2 NUSAP1 TMEM106C POLE2 UCK2 CCT3 GOT2 UNG NCAPG PSMB5 FEN1 SPAG5 FADD FOCAD RNASEH2A SNRNP25 FANCG CCNE1 DPP3 TUBG1 DLGAP5 FAH MRPL11 RAD51D TK1 GINS2 TRIM32 CCDC51 PSMD2 LIMA1 CKAP5 CDC20 CENPM FAM50B MCM5 SRSF1 HAUS4 CCNA2 RAD51 ZWILCH GBP2 PGAM1 SNUPN SMC2 MTHFD1 PAICS UBE2C TUBA1C LXN NUP93	up	***
GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN	0.0000000	0.0000000	0.9865463	-0.4710830	-2.485522	171	SLPI SLC31A2 ABHD5 FCN1 DENND5A MNDA MIR22HG PPP4R1 RTN3 AQP9 C5AR1 P2RY13 BCL2A1 NCF2 FRAT1 IGSF6 TRIB1 PILRA LILRB3 CLEC7A LITAF HLX NDEL1 SRGN TXN MCL1 ATP6V1B2 CD58 CFD PPT1 KIAA0513 BST1 VASP STX3 PLBD1 LY96 FAM49B ITPK1 TMBIM1 CTBS ID2 CD302 ARAP3 FCER1G PLEK EVI2A GCA PPP2R5A NRBF2 ANXA3 HCK NINJ1 S1PR4 HCAR3 SEC14L1 RAB31 TYROBP TREM1 CSTA SPATA2L RASSF2 RALB ACSL1 NOP10 BIN2 MME	down	***
GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP	0.0000000	0.0000000	1.0476265	0.5505188	2.484821	167	HELLS CDC45 BUB1B CENPF PBK NDC80 DEPDC1 BRCA1 TTK GINS1 RACGAP1 E2F8 KIF14 POLE ASPM PLK1 NUF2 CDCA8 AURKB ECT2 CDC6 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 PRC1 NCAPD2 HMMR KIF23 CEP55 MKI67 KIF15 BUB1 AUNIP TOP2A AURKA EME1 MCM7 CENPW CLSPN RRM2 WDHD1 RAD54L KIF11 MCM3 CHAF1B LMNB1 CDC25C LIG1 TOPBP1 CHEK1 ORC6 MAD2L1 RAD51AP1 SPC24 MRPS11 BRIP1 TADA2A INCENP CKS1B CBX5 ASF1B ANAPC5 CDK1 CENPH BIRC5 NCAPG DNA2 NEIL3 SPAG5 CENPP CCNE1 DLGAP5 TACC3 TK1 ESCO2 ANP32E FHL2 ATAD5 CKAP2 MCM5 CORO2A APOBEC2 CCNA2 PRIM1 PRR11 HDLBP SHCBP1 RAD51 ARHGAP11A WDR76 CPOX SMC2 CENPE ZBTB32	up	***
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN	0.0000000	0.0000000	1.0672100	0.5482754	2.484554	175	TRIP13 KIF20A HJURP KCNK5 CDC45 MCM10 CCNB1 GBAP1 KIF18B SORD BRCA1 RACGAP1 HILPDA ASPM CDCA8 AURKB CENPA ESPL1 TPX2 CCNB2 RBBP8 MCM4 MCM2 TYMS UMPS DTL ACY1 LIG3 SRPK1 MYL6B UQCC1 NME1 HMMR CISD1 KIF23 CEP55 CHAF1A MKI67 TP53BP1 FANCA LGMN TOP2A PUS7 VANGL1 POLA2 KIF2C MCM7 RRM2 RAD54L KIF11 CDC25C AIMP2 LIG1 DCTPP1 BLM CKS1B NCAPG2 NUSAP1 TMEM106C POLE2 UCK2 BIRC5 NCAPG FEN1 SPAG5 FANCG CCNE1 TUBG1 FAH LMNB2 RAD51D TK1 DTYMK GINS2 CCDC51 ZNF282 PFAS TIMM13 CKAP5 CDC20 PALB2 CENPM PPCDC MCM5 SRSF1 GINS3 IL12RB2	up	***
LINDGREN_BLADDER_CANCER_CLUSTER_2B	0.0000000	0.0000000	1.1866510	-0.4315208	-2.478047	334	RAMP3 CD52 IL1A FOXF1 SOX18 PECAM1 HHEX GLIPR2 LRRC8C DPYSL2 THBD LINC00472 FYN STXBP6 SAMHD1 GFOD1 CAV1 MYADM RTN3 FLVCR2 CLEC10A PRKAR1A BCL2A1 IER2 SEMA6D STARD4 SH2B3 DNAJC3 TACC1 LATS2 ENTPD1 CSRP1 IFI30 PARVG ANPEP LCP1 STOM NR4A1 JAM3 SIRPA TNS1 CRTAM SRGN EPB41L2 SLC7A2 EVI2B CYBRD1 SYNPO DAAM2 KLF4 AOC3 PLAUR NES DAB2 ZFAND5 ADAMTS9 SOCS2 GRK5 CLIC4 LAPTM5 COTL1 SELL CD302 LBH ALOX5AP EVI2A ACTG2 IL7R AFF1 CNRIP1 EMP3 PHTF2 SOCS3 LAMB2 TMTC1 JUN MT1L RAC2 PODXL GLIPR1 MALT1 YWHAZ LGALS2 RALB CST7 CELF2 MCAM PELI1 LMCD1 CALM1 RUNX3 PPTC7 TIMP2 TCF4 DUSP5 RELL1 COL15A1 MFNG RGS2 NRN1 ABI3BP BMP2K GEM ICAM1 MOB3B ARPC2 CDC42EP3 MS4A4A CXCR4 DHRS12 ALDH2 TRAF1 OSER1 NFKBIA ADORA2A KLRK1 B3GNT2 DNAJB9 SAMSN1 NRP2 MT2A IL16 DNAJB5 LYZ SLFN11 EGR1 CFL2 DKK3 HMGCS1 PRKCH ITGAL EBF1 MT1E GNG11 HLA-DRB1 AKAP12 TES SLC43A3 NFIL3 PDPN EDIL3 IL32 MAPK7 ARHGAP30 NFKBIZ EBI3 MYO1F MYO5A MT1X MYL9 ADAM19 MYLK GSN SON FERMT3 SPAG7 C3AR1 ANXA6 KLRG1 SERPING1 IL10RA EFEMP1 MT1G	down	***
GNF2_CKS2	0.0000000	0.0000002	0.7749390	0.6635735	2.474834	48	FOXM1 KIF20A FANCI CENPF NDC80 TTK GINS1 RACGAP1 ASPM PTTG1 CCNB2 MCM4 MCM2 TYMS PRC1 DTL ZWINT CCT2 HMMR TOP2A NUSAP1 CDK1 BIRC5 GMNN FEN1 DLGAP5 GINS2 CDC20 CKAP2 SNRPD1 CCNA2 SHCBP1 SMC2 CENPE	up	***
GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP	0.0000000	0.0000000	0.9545416	-0.4656427	-2.472026	174	MCOLN1 PPARG MIR22HG LPL GFOD1 SEC22C CORO1C GPCPD1 TBC1D7 ZCCHC2 TBC1D2 TSHZ1 TRIB1 GGA2 AVPI1 TXNIP CNST FBXO7 RRAGC LINC01010 IFI30 ABCG1 ZBTB21 SPRY2 CRTAM TMEM38B CD37 ATP6V1B2 RHOB FBXL5 MOAP1 ACSL3 ID3 DAB2 TNFSF15 MAP1LC3B STX3 TMBIM1 ITGAX ATF3 ZBTB43 UBASH3B FKBP15 AFF1 NRBF2 PI4K2A MMP19 HEXB CLN8 NRROS BCAR3 SGK1 SH3BP5 HIC1 TMEM251 KBTBD8 KLF2 RNASEK CD164 AKIRIN2 TGIF1 COL15A1 LGALS3 DOK2 TMEM70 BRI3 CCR1 PLEKHO2 AMD1 SERTAD1	down	***
CROONQUIST_NRAS_SIGNALING_DN	0.0000000	0.0000000	0.8266573	0.6177887	2.470102	67	TRIP13 FOXM1 CHEK2 BUB1B CCNB1 NDC80 GINS1 TRAIP STIL PLK1 AURKB CENPA PTTG1 CDC6 TPX2 CCNB2 MCM4 MCM2 MYBL2 ZWINT CHAF1A MKI67 TOP2A AURKA KIF2C MCM7 KIF11 MCM3 CDC25C CHEK1 CKS1B PLOD2 CDK1 SPAG5 KIF22 TK1 POLD1 BRD8 CDC20 HMGA1	up	***
REICHERT_MITOSIS_LIN9_TARGETS	0.0000000	0.0000001	0.8012156	0.7788433	2.468944	26	KIF20A CCNB1 CENPF CDCA2 ASPM PLK1 CENPA CCNF NCAPD2 LMLN HMMR KIF23 CEP55 MKI67 TOP2A AURKA KIF2C NUSAP1	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP	0.0000000	0.0000000	0.8634154	-0.4909785	-2.468763	127	CXCL3 SOWAHC ZC3H12C MIR22HG BACH1 FOSL1 UBE2FP1 TRIB1 CNST HBEGF EIF5 SPIRE1 ZBTB21 PPP3CC PLAUR PXDC1 MAP1LC3B MAFG ATF3 ZBTB43 BRF2 INHBA RYBP VPS37A CREM CPEB4 HSPA1B DNAJA1 RCAN1 IFRD1 PNPLA8 KBTBD8 ZNRF3 RNF24 SLC3A2 CHORDC1 SAV1 AKIRIN2 JMJD6 SMCR8 C16orf72 GNA13 N4BP2L2 JUND SERTAD1 TMEM217 CREBBP OSER1 MAFK DNAJB9 TNFSF9 KIF1B SAMSN1 RORA ZFAND2A PMAIP1 HERPUD1 SLC19A2 YRDC DNAJB1 NFIL3 HSPB8 SRXN1 CASP3 EMP1 PNP CBLL1	down	***
HSD17B8_TARGET_GENES	0.0000000	0.0000000	1.4604515	0.4991347	2.468530	484	MCIDAS TRIP13 FOXM1 KIF20A HJURP CEP89 TICRR PARPBP MCM10 FANCI ZNF273 C1QTNF6 TROAP CHEK2 BUB1B NUP107 NEK2 CENPF POLQ UBE2T C21orf58 MND1 PBK KIF18B TTF2 NDC80 PRIM2 DEPDC1 IFI27L1 BRCA1 CDCA7 ZNF138 TTK GINS1 C6orf141 CDCA2 AGFG2 IQGAP3 E2F8 GTSE1 DBF4B KIF14 ANLN TRAIP DNMT3B POLE ASPM STIL ANKRD24 BAMBI CR1L DGCR8 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 E2F3 CCNB2 NBR2 GLB1L3 UHRF1 CDC25A MYBL2 PRC1 XRCC2 KCNMB4 DTL TDRKH MCM8 MIS18A RCCD1 ZWINT P2RX2 ZNF107 LSM5 ZNF726 AARS2 WDR62 C5orf34 CCDC150 ZNF730 MELK HMMR EXO1 C19orf48 KIF23 CEP55 RPL39L FOXA1 MKI67 KIF15 AP4M1 KNTC1 RHNO1 BUB1 TOP2A EME1 THBS4 KIF2C MCM7 E2F2 CENPW POC1A RSRC1 ANKRD19P RRM2 CDCA5 HOXC6 RAD54L MRPL27 FANCD2 GPSM2 MCM3 C7orf57 CDC25C ZNF785 ZNF530 BRD9 ABCB6 TOPBP1 ZYG11A MAD2L1 CKAP2L CENPO RAD51AP1 THAP10 SPC24 BRIP1 RAD18 BLM LRRC45 FADS2 TULP3 LEF1-AS1 INCENP CKS1B NCAPG2 CDKN2C C12orf75 ASF1B CDK1 RFWD3 BIRC5 ATP2A1 C1orf112 NUDT2 E2F1 UNG NCAPG DNA2 SPAG6 FEN1 SPAG5 THAP8 MTBP ATAD3A DIAPH3 RECQL4 CENPP C9orf43 FGFR1OP RNASEH2A NET1 LGR5 ZNF687 INTS7 CCNE1 CEP192 CDC23 DLGAP5 SATB2 FAM47E-STBD1 TACC3 MNS1 KIF22 UBE3D FBXO15 TK1 CHTF18 CENPQ ESCO2 GINS2 ANP32E TCEA1 KIF20B C15orf41 POLD1 CEP128 ATAD5 CENPK SASS6 CKAP5 BRD8 COG1 CDC20 RPA1 RPUSD1 FANCM MCM6 HOXA3 MCM5 RPPH1 TDP1 C1orf109 GINS3 DOLPP1 RCC1 CDH11 ATAD2 CEP152 TCERG1 ALG8 LRRC14 ZNF519 CCNA2 RBM42 DZIP3 PRR11 ZNF90 SNRPD2 ZNF66 SHCBP1 RFC5	up	***
ZWANG_CLASS_3_TRANSIENTLY_INDUCED_BY_EGF	0.0000000	0.0000000	0.9969862	-0.4533804	-2.465657	206	WEE1 IL1A OLR1 DLC1 KLF13 CD55 SOWAHC ZC3H12C CPEB2 IL1B RAPGEF2 CLDND1 SIK1 OTUD1 MYADM GPCPD1 STX11 IL1RN TRIB1 CASP9 CCNL1 NCEH1 B3GNT5 HBEGF SGMS2 LATS2 CHMP1B MTF1 MAP3K8 NR4A1 TFRC MCL1 TIPARP CSRNP1 RN7SL368P RN7SL600P ITPRIP ZSWIM6 KLF4 PLAUR TJP1 ADAMTS9 DENND3 PER2 NFKB1 RBMS1 CXCL2 ATF3 PER1 DUSP1 SMAD7 HES1 MAFF AFF1 MMP19 SERTAD2 IL6 SOCS3 ARL5B ETS1 HRH1 JUNB RCAN1 PPP1R15A FERMT2 MBNL2 SNRK FOS PELI1 PTP4A1 HIVEP2 MBP PPTC7 FOSB TGIF1 MIR23A DUSP5 NAB1 ATXN1 TOB1 GATA6 RIMKLB RGS2 ETS2 CCL20 GEM CEBPD EPHA2 MAFK EDN1 RORA NRG1 PURB ANO6	down	***
SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6	0.0000000	0.0000000	1.3575741	0.5034047	2.460495	408	TRIP13 FOXM1 HELLS KIF20A EGLN3 HJURP PKP2 AK4 CDC45 PARPBP MCM10 FANCI ELOVL6 TROAP BUB1B NEK2 UGT8 CCNB1 CENPF SLC9A2 IGF2BP3 PBK KIF18B TTF2 SLC2A1 MUC16 NDC80 PRIM2 DEPDC1 TBRG4 TTK GINS1 RACGAP1 E2F8 GTSE1 KIF14 ASPM NABP2 YEATS4 CDCA8 AURKB CENPA PTTG1 CDC6 SFXN1 TPX2 GAPDH CCNB2 STC2 MCM4 TYMS XPNPEP1 CDC25A MYBL2 PRC1 ORC1 DTL GINS4 NCAPD2 ZWINT CDT1 KAZALD1 NME1 LDHB WDR62 RUVBL2 MELK HMMR EXO1 GPR37 KIF23 CEP55 MKI67 KIF15 KNTC1 WASF1 BUB1 FANCA TOP2A CCT5 AURKA VANGL1 YKT6 SNCG KIF2C MPHOSPH9 RRM2 PRKDC WDHD1 RAD54L PKM KIF11 GPSM2 LMNB1 CDC25C PFN2 YEATS2 CHEK1 DNAJC9 MAD2L1 PFKP RAD51AP1 BRIP1 CAD SLC25A10 PSRC1 THOP1 NCAPG2 CDKN2C CMAS NUSAP1 PLOD2 CBX5 CDK1 POLE2 EXOSC2 BIRC5 NCAPG DNA2 KIF2A PSAT1 NEIL3 SSX2IP EZH2 SPAG5 ARTN SEMA3A PRKAA2 RECQL4 DENND1A FGFR1OP SRD5A1 PA2G4 CCNE1 TUBG1 DLGAP5 MRGBP UBAC1 PSMA5 TRMU CTSV GSS TACC3 TK1 DTYMK CENPQ POMT2 GINS2 AGPAT5 STEAP1B SAP30 TWF1 MAGOHB CDC7 STRN4 CDC20 CENPM HMGA1 UBE2V2 MCM6 ZNF248 PRMT1 CKAP2 MCM5 GINS3 LSM4 CHRNA5 WDYHV1 ATAD2 TSR1 NUP62 AP2S1 AGMAT CCNA2 ADM PRIM1 SHCBP1 ELOVL4 HK2 TUBA4B SNX7 CARHSP1 ZWILCH	up	***
GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP	0.0000000	0.0000000	1.0476265	0.5429162	2.460269	175	TRIP13 KIF20A EYA1 HJURP CDC45 TICRR PARPBP MCM10 BDH1 BUB1B NEK2 CENPF MPP6 MND1 KIF18B NDC80 PIF1 BRCA1 TTK GINS1 E2F8 POLE ASPM STIL NUF2 AURKB CENPA ESPL1 CDC6 CCNB2 FIGNL1 UHRF1 XRCC2 CCNF NCAPD2 WDR90 MELK EXO1 KIF23 CEP55 PAQR4 BUB1 TOP2A EME1 CLSPN RRM2 TTLL12 CDCA5 AKAP1 RAD54L MCM3 LIG1 CKAP2L SPC24 DSCC1 PKMYT1 BRIP1 FNTB CKS1B NCAPG2 C12orf75 NUSAP1 ASF1B BIRC5 GMNN PSAT1 NEIL3 EZH2 SPAG5 CENPP SPEF1 DLGAP5 SNRPA MNS1 GALNS KIF22 TK1 ESCO2 PKP4 KIF20B	up	***
GNF2_PTPN4	0.0000009	0.0000331	0.6594444	-0.5931467	-2.458539	43	GPR65 FYN CTSW GNPTAB CCL4 XCL2 PRF1 KLRD1 MATK CD160 KLRB1 IL2RB JAK1 PTGER2 CD7 TBX21 CST7 RUNX3 NKG7 IL18RAP KLRK1 RORA KLRF1 PRKCH ITGAL S1PR5	down	***
WONG_ENDMETRIUM_CANCER_DN	0.0000001	0.0000045	0.7049757	-0.5440852	-2.457513	65	EDNRB TBX3 SFRP4 WNT4 PID1 JPH4 CTSW LDB2 GAS6 LTBP4 MASP1 PEG3 RUNX1T1 KIF26A CNRIP1 RBP7 SYNPO2 HIC1 EHD2 TSHZ3 KLRC2 XYLT1 MME SCARA5 MICU3 LMOD1 PARM1	down	***
ISHIDA_E2F_TARGETS	0.0000000	0.0000004	0.7614608	0.6698702	2.456750	46	TRIP13 CCNB1 UBE2T CDCA7 E2F8 ANLN AURKB PTTG1 CCNB2 PRC1 CDT1 MKI67 BUB1 TOP2A KIF2C RRM2 MCM3 LIG1 DCTPP1 CDKN2C NUSAP1 ASF1B CDK1 DNA2 FEN1 EZH2 CCNE1 TK1 CDC20 RPA1 CCNA2 PRIM1 RAD51 SMC2	up	***
GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP	0.0000000	0.0000000	0.9325952	-0.4664024	-2.454111	168	RAB11FIP1 CD52 HMOX1 FCN1 PECAM1 MNDA LTA4H FBP1 GPR65 LRRFIP1 HSD17B11 LY86 INPP5K MYD88 C5AR1 YPEL5 TMX4 DPEP2 TACC1 ASAH1 NR4A1 CD37 CST3 EVI2B PPT1 SCP2 KIAA0513 BST1 KLF4 ZCCHC24 ITM2B PLBD1 CTSD LAPTM5 COTL1 CD302 EVI2A CARS2 MPC1 MAPRE2 ARHGDIB PRCP TECR CTSS IFNGR1 RASSF2 PPM1F CELF2 FOS KLF2 TIMP2 RPL21 CD86 FCGRT RGS2 TSPO JUND EIF3F SELPLG CCDC69 ARRB2 MS4A4A ALDH2 SCPEP1 RPS13 S100A4 ICAM3 THEMIS2 EID1 CNN2 LYZ PHYH CHP1 CRTAP NR4A2 CRBN EIF3L ZFP36	down	***
GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_UP	0.0000000	0.0000000	0.9214260	-0.4712371	-2.453626	161	CXCL3 IL1A USP12 PPARG ADTRP IL1B DCSTAMP P2RY1 RAPGEF2 INSIG1 CCRL2 ST3GAL6 NEDD4L FOSL1 AQP9 TBC1D7 SFR1 OTUD4 IL23A STARD4 ATP2B1 SGMS2 HECW2 PPP1R15B TNIP3 MAP3K8 RGCC ADRB2 SPRY2 TXN IL10 CSRNP1 MOAP1 ACSL3 PLAUR TNFSF15 SPAG9 RIT1 CXCL2 ID2 TAF9 DUSP1 PLEK INHBA TP53BP2 RASGEF1B MMP19 RYBP SYNPO2 NSMAF JUN ARL5B PLK3 TMEM251 FERMT2 CCR7 HOMER1 GPRC5A DENND4A SNX9 SLC3A2 PTP4A1 NIPAL4 SAV1 TEX14 DUSP5 ADORA2A-AS1 ETS2 CCL20 GEM LDLRAD4 IL18 ABL2 MIR155HG FBXO30 NLRP3	down	***
GSE3982_NEUTROPHIL_VS_NKCELL_UP	0.0000000	0.0000000	0.9759947	-0.4649877	-2.453362	171	SLPI SLC31A2 SLC12A6 DENND5A TBX3 MIR22HG LYL1 AATK PPP4R1 BACH1 FOSL1 CDC42EP2 C5AR1 MSRA NEDD9 CD9 IL1RN ANPEP PCDH12 HLX ADIPOR1 LHX6 SPI1 UBE2D3 ATP6V1B2 FBXL5 AGO4 CFD SDCBP UHRF1BP1L DENND3 KLF7 SNIP1 ERP44 CD302 IGFBP2 ACTR3 TM6SF1 B9D2 ARL4A PINK1 SLC6A6 GNAQ TM9SF2 ANXA3 NCOA1 FOXN3 BTG1 SGK1 RNF141 PPP6C SEC14L1 ATP11A REL CAP1 RNF24 OGFRL1 ACSL1 PELI1 KLF2 PNPLA3 FPR2 GNG5 CCR1 ADAM10 SERINC3 XKR8 IQSEC1 TAB2 NLRP3 ICAM3 ARPC5 DNAJB9 CNTNAP3B DAZAP2	down	***
GO_IMMUNOGLOBULIN_COMPLEX	0.0000000	0.0000001	0.8012156	0.6087314	2.447755	69	IGHV4-61 IGHV4-4 IGLV4-69 IGLV3-27 IGKV3D-15 IGKV1-17 IGKV2D-29 IGLV1-36 IGKV3-15 IGKV1-6 IGKV1-16 IGKV1-27 IGLV3-9 IGKV4-1 IGLC7 LIME1 IGKV2D-28 IGLV3-10 IGLV1-44 IGKV1-5 IGKV2-24 IGKV1D-33 IGHV3-48 IGLV1-40 IGKV1-9 IGHG1 IGLV7-43 IGLV6-57 IGHM IGLV1-47	up	***
ODONNELL_TFRC_TARGETS_DN	0.0000000	0.0000000	0.8870750	0.5702573	2.443345	108	TP63 FOXM1 HELLS KIF20A BUB1B CCNB1 CENPF MND1 NDC80 DEPDC1 DEPDC1B TTK GTSE1 KIF14 ANLN ASPM PLK1 AURKB CENPA ECT2 CDC6 RAD54B MYBL2 PRC1 RANBP1 HMMR CEP55 CHAF1A MKI67 BUB1 TOP2A AURKA RRM2 KIF11 FANCD2 CCDC148 CKAP2L TADA2A NRTN CKS1B CDK1 POLE2 BIRC5 DNA2 MIR3939 DIAPH3 SLC12A1 DLGAP5 TACC3	up	***
GNF2_S100A4	0.0000008	0.0000308	0.6594444	-0.6030222	-2.440939	39	FCN1 PECAM1 HSD17B11 NCF2 IGSF6 PILRA LILRB3 FGR DPEP2 MCL1 CASP1 CPVL COTL1 FCER1G HCK TYROBP DOK2 CCR1 RGS2 ARRB2 S100A4 THEMIS2 SH3BGRL3	down	***
PODAR_RESPONSE_TO_ADAPHOSTIN_UP	0.0000000	0.0000000	0.8513391	-0.4828402	-2.438437	129	HMOX1 CD55 MIR22HG FYN CD44 BACH1 YPEL5 NCF2 TRIB1 IL23A ANXA1 ADAM17 HSPB1 CSGALNACT2 KLF6 SLC7A11 CLK1 ZEB1 ZFAND5 MAP1LC3B STX3 MAFG ITGAX ATF3 ID2 PNRC1 ZBTB43 CCSER2 DUSP1 PLEK MAFF CREM JUN HSPA1B IFNGR1 PPP1R15A IFRD1 HSPA13 MBNL2 MFAP4 MORC3 SLC3A2 KLF2 DGKG DUSP5 C16orf72 HBP1 GABARAPL1 STX12 RGS2 ZNF267 CLEC2B JUND NEK1 MGAT2 IER5 CDKN1C OSER1 DNAJB9 TNFSF9 ZNF165 ATF4 PMAIP1 RB1CC1 SLC38A2 TUBA1A DNAJB4 DNAJB1 TES FNDC3A WDR26 CCPG1	down	***
GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP	0.0000000	0.0000000	1.0376962	0.5332642	2.435955	185	TRIP13 HELLS KIF20A HJURP CDC45 FANCI CCNB1 CENPF TIMELESS POLQ NDC80 PHGDH RACGAP1 SLC27A2 GMPS PMS2P5 ASPM STIL PLK1 CDCA8 CENPA PTTG1 ESPL1 TPX2 CCNB2 GOLGB1 RBBP8 MCM4 MCM2 PRC1 DTL SRPK1 ZWINT CDT1 MELK HMMR NUDT1 CEP55 KIF15 KNTC1 AURKA POLA2 KIF2C MCM7 MPHOSPH9 RRM2 RAD54L KIF11 CDC25C MCCC2 SLC9A3R1 MAD2L1 RAD51AP1 BLM IDH2 NUSAP1 CDK1 GMNN NCAPG NEIL3 FEN1 FGFR1OP IFT52 FANCG CCNE1 VIPAS39 DLGAP5 TACC3 LMNB2 KIF22 MRPL11 TK1 DTYMK GINS2 RNF187 CKAP5 CDC20 CENPM FAF1 CDR2 MCM6 TDP1 SNRPD1 GINS3 CREB3L2 STK39 CCNA2 PRIM1 DCPS TTC31 RAD51 TPGS2 GRAMD1B	up	***
GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN	0.0000000	0.0000000	0.9653278	-0.4561408	-2.435223	185	ARHGAP31 IL1A CXCL16 HVCN1 SOWAHC ZC3H12C GPR65 RAPGEF2 CCRL2 BCL2A1 IL1RN IGSF6 FGR IER2 SEMA6D RBM7 ADAM17 ITGA5 BTG2 MAP3K8 HDC SERPINB9 NR4A1 NFE2L2 MCL1 PTPN12 CSRNP1 STAT5A PTGIR CCL22 FOXO1 PTPRO REST VASP CDKN1A CXCL2 PNRC1 DUSP1 N4BP1 PIK3R5 KPNA3 MAFF HCK AREG IL6 DDHD1 EBAG9 SOCS3 JUNB PTGER4 SKIL IFRD1 GLIPR1 CD83 SMU1 PSTPIP2 OSM GRASP RBM22 FAM177A1 ACSL1 UBXN2A EHD1 GSAP TGIF1 DUSP5 NAB1 IFNAR1 CD86 PIM1 GPR84 SOD2 TAGAP PLEKHO2 ETS2 ICAM1 SPIB NLRP3 TRAF1 MCOLN2 TNFSF9 SAMSN1 SPATA13 HERPUD1 CSF2RB NR4A2 CX3CR1	down	***
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN	0.0000000	0.0000000	1.0073180	0.5361621	2.434618	177	TRIP13 KIF20A HJURP MCM10 BDH1 FANCI BUB1B CCNB1 CENPF CDK4 RACGAP1 HILPDA ASPM AURKB CENPA ESPL1 CDC6 TPX2 GAPDH CCNB2 MCM4 MCM2 TYMS CDC25A DTL SRPK1 ZWINT MYL6B SPDL1 NME1 RANBP1 MELK HMMR NUDT1 CEP55 EMC9 KIF15 MRPL15 TP53BP1 TOP2A AURKA KIF2C MCM7 RRM2 KIF11 AIMP2 CHEK1 RAD51AP1 DCTPP1 TBC1D8 BLM PHB CKS1B NCAPG2 TMEM106C POLE2 UCK2 CCT3 GOT2 POLR3K UNG NCAPG TRAP1 PSMB5 FEN1 SPAG5 LRRC42 RNASEH2A POLR2H FANCG DPP3 TUBG1 DLGAP5 FAH LMNB2 MRPL11 TK1 MSRB2 GINS2	up	***
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_UP	0.0000000	0.0000006	0.7477397	-0.5357742	-2.433610	70	CXCL3 IL1B GPR65 PTPRE CD44 AQP9 IDI1 BCL2A1 TRIB1 CASP9 EIF4A1 EIF5 KLF10 PPP2R2A NFE2L2 TFEC MAP2K3 TPP1 CCL3 NFKB1 CXCL2 M6PR PLEK OXSR1 HCAR3 GABARAPL2 SKIL	down	***
GSE14415_NATURAL_TREG_VS_TCONV_DN	0.0000000	0.0000000	0.9759947	0.5406398	2.432977	162	PRLR HELLS CDC45 BUB1B TRNP1 CENPF IGF2BP3 PBK NDC80 BRCA1 TTK GINS1 AGFG2 IQGAP3 E2F8 KIF14 ASPM PLK1 NUF2 CDCA8 TPX2 CCNB2 UHRF1 MCM4 MCM2 PRC1 NCAPD2 HMMR KIF23 CEP55 KIF15 BUB1 AUNIP TOP2A AURKA MCM7 CLSPN RRM2 WDHD1 RAD54L KIF11 MCM3 CHAF1B LMNB1 CDC25C LIG1 TOPBP1 CHEK1 MAD2L1 CKAP2L SPC24 BRIP1 BLM NRTN CKS1B CBX5 ASF1B CDK1 CENPH BIRC5 XRRA1 NCAPG NEIL3 SPAG5 CENPP DLGAP5 TACC3 OSBPL3 TK1 CHTF18 ESCO2	up	***
GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP	0.0000000	0.0000000	0.9436322	-0.4620404	-2.432875	170	SLC31A2 PPARG CD55 FBP1 RAPGEF2 MIR22HG PTPRE CLDND1 CD44 CCRL2 BACH1 AQP9 PAFAH1B2 NR3C1 IL1RL1 BCL2A1 CD1C ATP2B1 EIF1 EIF5 KLF10 KLF6 CLK1 UBE2D3 TXN MCL1 MOAP1 BNIP2 ADO MAP1LC3B TMED5 CDKN1A PAPSS1 CCND2 ZBTB43 CD53 RNF139 VAMP5 RUFY3 MAFF BTG1 SERTAD2 RBPJ ELF1 JUN SHOC2 RPL9 IFRD1 HSPA13 RGS13 RALB SNRK RRN3 ICAM2 ING3 TGIF1 HECW1 CTNNAL1 MEIS3P1 HBP1 GNG5 MAGOH GATA6 ZNF267 ETS2 GEM BNIP3L ABL2 ARPC2	down	***
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN	0.0000000	0.0000000	0.9101197	-0.4661357	-2.430097	156	DPYSL2 ST6GALNAC3 SIK1 RGS9 DDX6 CITED2 IL1RL1 AGPAT4 ZEB2 STARD4 ATP2B1 BTG2 SERINC1 FZD4 KLF6 GATA3 NR4A1 RGCC IL18R1 ATP10A RHOB IL10 AHNAK ZFAND5 OSTF1 ATF3 HOPX ARC DUSP1 TBC1D4 HGSNAT SLC25A3 ELF1 NEK7 SLC35E4 STAT4 CUL4A ETS1 GLUD1 PLK3 JUNB EEA1 GPR183 PTGER2 GRASP COBLL1 GPRIN3 MBP FOSB JMJD6 DCK KCTD10 PIM1 TAGAP THAP11 RGS2 SPOCK2 SYT11 HSPA2 IL18RAP RAB5A HSP90AA1 ULK2 ADORA2A KLRK1 FDFT1 RORA NABP1 IQGAP1 ZFAND2A TOX2 ATF4 ENDOD1 HIPK1 ITGB1 ARL4D TUBA1A CD69 DNAJB1 ATP2B4 PLCB4 SIRT1 EBI3 MYO1F EMP1 PNP FAM107B	down	***
GREENBAUM_E2A_TARGETS_UP	0.0000000	0.0000005	0.7477397	0.7743210	2.427509	25	SCIN HS3ST1 CCNB1 TTK RACGAP1 ANLN ECT2 CCNB2 MKI67 BUB1 TOP2A AURKA KIF2C KIF11 PFKP CDKN2C NUSAP1	up	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_UP	0.0000000	0.0000000	0.9436322	-0.4577897	-2.426533	181	SMAD6 CD52 SASH1 SWAP70 DENND5A TAL1 HHEX GATA2 PTPRE RAMP2 ARRDC4 FYN CD44 LY86 LMO2 SAMHD1 MYADM AQP9 MEF2A TGFBR2 TLCD2 ANXA1 MAN2B1 UBL3 CD33 ADAM17 PCYOX1 ENTPD1 ZNF503 LITAF PPP3CA SIRPA IL18R1 TFEC ARRB1 AHNAK ST3GAL2 TJP1 SOCS5 ITIH5 ITGAX C9orf72 PTGER3 SMAD7 PLEK KLRD1 ANXA3 TDRD7 HCK PROCR PRCP RNF149 RGS18 MITF RAB31 KCTD12 TYROBP GLIPR1 CD7 OGFRL1 CD34 MOB1A RHOQ RRAS IRF5 ZNF521 VAV3 ITGA9 TSC22D1 CD86 CD81 PLA2G15 GEM IL18RAP IER5 S100A4 SAMSN1 RORA THEMIS2 HEBP1 EID1 FCRL1	down	***
GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000000	0.0000000	0.9653278	-0.4598981	-2.426509	171	KRT81 SWAP70 ABHD5 PECAM1 HHEX GPR65 PTPRE AATK LMO2 PPP4R1 BACH1 RHOA ANXA1 DPEP2 SH2B3 CD33 SERINC1 LUZP1 HDC CAV2 ZFYVE16 BAG1 FLI1 ZMIZ1 PTPN12 EVI2B TLE4 BST1 FAM124B CDIP1 DRAM1 MAP1LC3B TM6SF1 CLK4 TAF9 PPP2R5A TM9SF2 LMBRD1 FRY AREG BCAR3 PSEN1 CRNKL1 SF3B1 DHX15 STX7 PSTPIP2 YWHAZ RALB NDUFV2 PLCG2 RHOQ PELI1 PTP4A1 AZI2 NOP10 CHPT1 VAV3 MILR1 SERPINB1 BAZ2B GALC HBP1 PLAA OPN3 CYB5R4 ESYT1 ALDH2 OSER1 CD19 MARC1 KIT DAZAP2 CREG1 LYZ HTRA2 CHP1 SVIL ZNF106 OSGIN2 TREM2 SH3GLB1 RB1CC1 KBTBD11	down	***
GNF2_MYD88	0.0000002	0.0000099	0.6901325	-0.5665879	-2.418239	51	PTPRE MYD88 RHOA SH2B3 MAN2B1 MCL1 CASP1 OSTF1 SELL CD53 FCER1G FKBP15 CMTM6 ACTR2 TYROBP RAB8A RPS6KA1 CAP1 RGS2 SELPLG ARPC5 PAK2 THEMIS2 DAZAP2 IQGAP1 CYBA SH3BGRL3 SKAP2 TNFRSF1B PYCARD TMEM127 DOCK2 HCLS1 LSP1	down	***
GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN	0.0000000	0.0000000	0.8870750	-0.4728631	-2.417123	141	SEMA6B FCN1 MIR22HG FLVCR2 SLC15A3 IL1RN SLC11A1 CD36 EIF1 CLEC7A EMILIN2 IFI30 KLF10 ANPEP ADIPOR1 SIRPA CD93 GRN TFEC SRGN SPI1 CYBRD1 DUSP3 PPT1 SDCBP BST1 PLAUR ZFAND5 PLBD1 CTSD CDKN1A P2RY2 VIM HPSE PLEK DSE NINJ1 VAMP3 PGD SOCS3 IFNGR1 PPP1R15A ACSL1 SORT1 FXYD6 TIMP2 SERPINB1 APLP2 SOD2 LGALS3 CTIF RXRA ICAM1 BNIP3L CDC42EP3 SREBF2 GLUL DAZAP2 NRG1 CREG1 LYZ EGR1 ZYX S100A8 FPR1	down	***
HALLMARK_E2F_TARGETS	0.0000000	0.0000000	0.9969862	0.5287633	2.416240	182	TRIP13 HELLS CHEK2 BUB1B NUP107 TIMELESS UBE2T KIF18B PRIM2 DEPDC1 TBRG4 BRCA1 GINS1 CDK4 RACGAP1 E2F8 POLE PLK1 CDCA8 AURKB PTTG1 ESPL1 CCNB2 MCM4 MCM2 CDC25A MYBL2 PMS2 GINS4 NCAPD2 WDR90 NME1 RANBP1 MELK HMMR MKI67 TOP2A AURKA POLA2 POLD2 KIF2C MCM7 RRM2 MMS22L PRKDC MCM3 LMNB1 LIG1 CHEK1 ORC6 MAD2L1 RAD51AP1 DCTPP1 SPC24 DSCC1 CKS1B CDKN2C CBX5 ASF1B CDK1 BIRC5 UNG EZH2 NUP205 SPAG5 DIAPH3 PA2G4 RNASEH2A DNMT1 CCNE1 TUBG1 DLGAP5 TACC3 KIF22 SSRP1 TK1 ANP32E POLD1 RAD50 CDC20 CENPM PPP1R8 HMGA1 POP7 RPA1 MCM6 MCM5 SRSF1 GINS3	up	***
KAUFFMANN_MELANOMA_RELAPSE_UP	0.0000000	0.0000001	0.7881868	0.6264929	2.409192	57	CDC45 CHEK2 CENPF POLQ BRCA1 PTTG1 CDC6 MCM4 XRCC2 EXO1 CHAF1A FANCA TOP2A EME1 MCM7 RRM2 RAD54L FANCD2 MCM3 CHEK1 ORC6 MAD2L1 RAD51AP1 BRIP1 RAD18 BLM GMNN NEIL3 FANCG GINS2 MCM6 TDP1 MSH2 RFC5 RAD51 SMC2 PPIA	up	***
BENPORATH_PROLIFERATION	0.0000000	0.0000000	0.9325952	0.5451297	2.407995	136	NEK2 CENPF UBE2T GGCT MND1 PBK NDC80 PRIM2 CDCA7 TTK RACGAP1 ANLN ASPM NUF2 CENPA PTTG1 CCNB2 MCM2 TYMS MYBL2 PRC1 DTL SRPK1 AVL9 CDT1 RANBP1 EXO1 BUB1 FANCA TOP2A AURKA RRM2 CDCA5 PDCD5 RAD54L GPSM2 MCM3 CHAF1B KDELR2 MAD2L1 RAD51AP1 PKMYT1 IDH2 PARP1 PPIL1 KNSTRN CKS1B CDK1 BIRC5 C1orf112 NCAPG EZH2 SPAG5 ILF2 CTSV DTYMK CSNK1G1 S100A9 DAP3 MAGOHB DCUN1D5 CENPM SNRPD1 GINS3 PSMB4 ATAD2 SUV39H2 PRPF18 MSH2 FAM3C	up	***
FUJII_YBX1_TARGETS_DN	0.0000000	0.0000000	0.9865463	0.5306475	2.407854	176	DKK1 TRIP13 PTGES FOXM1 HELLS MDM1 PARPBP MCM10 FANCI BUB1B TIMELESS TTF2 DEPDC1 BRCA1 DEPDC1B CDCA7 ASPM CDC6 FIGNL1 UHRF1 MCM4 MCM2 RAD54B CDC25A MYBL2 CCNF DTL ZWINT CDT1 CASP2 MELK EXO1 KIF23 CHAF1A TOP2A CCT5 ODF2 POLA2 MCM7 RRM2 PRKDC KIF11 FANCD2 MCM3 LMNB1 CDC25C LIG1 CHEK1 MAD2L1 BRIP1 SKP2 CKS1B NCAPG2 NUSAP1 ASF1B DMKN POLE2 UNG BPGM NEIL3 FEN1 METTL3 CBX1 MAD2L2 RNASEH2A CDC23 SLC26A2 UBAC1 TRIO SSRP1 TK1 DTYMK DBN1 ENAH MSI2 GINS2 SPA17	up	***
KAMMINGA_EZH2_TARGETS	0.0000000	0.0000008	0.7477397	0.6835806	2.406785	38	NEK2 CDCA7 AURKB ECT2 CCNB2 MCM4 MCM2 PRC1 MKI67 TOP2A AURKA CDCA5 SETDB1 MCM3 TOPBP1 MAD2L1 AHCY NUSAP1 POLE2 GMNN	up	***
GSE45365_WT_VS_IFNAR_KO_BCELL_DN	0.0000000	0.0000000	0.9545416	0.5393145	2.405976	151	SLC16A14 FOXM1 KIF20A ADH1C PCDHGA10 PARPBP C1QTNF6 TROAP CENPF POLQ UBE2T KIF18B SLC2A1 NDC80 DEPDC1 DEPDC1B TTK CDCA2 KIF14 FOXE1 ANLN NIPSNAP1 NUF2 AURKB CENPA PTTG1 ESPL1 CCNB2 BCL2L14 IGFBPL1 ALDOC KIF27 ZNF608 COQ3 CEP55 MKI67 EMC9 CYP24A1 BUB1 TOP2A CDCA5 TMEM45A WDHD1 PCDHGB7 KIF11 CKAP2L RAD51AP1 SPC24 DPY19L1P1 SLITRK6 SLC28A2 TST THPO FLNB FGGY NUSAP1 ASF1B DNER BIRC5 ENPP3 NEIL3 FEN1 SPAG5 SLC35F3 DIAPH3 CASC1 FGFR1OP	up	***
WU_APOPTOSIS_BY_CDKN1A_VIA_TP53	0.0000000	0.0000006	0.7477397	0.6384511	2.405807	51	FANCI FAT2 ZNF84 CCNB1 UBE2T PBK TTK RACGAP1 ANLN ASPM AURKB TPX2 MCM4 MCM2 TYMS PRC1 SPDL1 EXO1 CEP55 MKI67 KNTC1 BUB1 AURKA WDHD1 MCM3 CDK1 NCAPG HMGB1P5	up	***
HESS_TARGETS_OF_HOXA9_AND_MEIS1_DN	0.0000000	0.0000008	0.7477397	-0.5164452	-2.405693	78	CXCL3 CD300LF IL1B LIPA TRPV2 LPL EGR2 SAMHD1 MYADM AQP9 C5AR1 SLC11A1 FGR ANXA1 CLEC7A BTG2 LITAF SIRPA MCL1 MSR1 MPEG1 KLF4 DAB2 STX3 GRK5 ID2 DUSP1 PLEK CPT1A HCK CTSS MITF FOS CHIA EHD1 FPR2	down	***
VILLANUEVA_LIVER_CANCER_KRT19_UP	0.0000000	0.0000000	0.9436322	0.5399867	2.403550	148	KIF20A HJURP MCM10 FANCI GABRB3 C2CD4A TROAP DROSHA JPH3 NDC80 DEPDC1B GAL3ST1 TTK GINS1 ANLN STIL CDCA8 PTTG1 ECT2 SOX9 TPX2 CDC25A COL22A1 MCM8 ZWINT AP1G2 SIPA1L3 CASP2 MELK KIF23 CEP55 MKI67 KIF15 KNTC1 BUB1 TOP2A SFI1 KIF2C RAD54L GPSM2 LMNB1 SOX4 CKAP2L CENPO RAB13 BLM ZNF605 DHRS13 NCAPG DNA2 EZH2 GOLGA3 ZNF354A DCLRE1C DLGAP5 MAPK13 SALL4 ZNF300 KIF20B CDC7 NR6A1 CDC20 CENPM	up	***
AMIT_EGF_RESPONSE_120_HELA	0.0000002	0.0000090	0.6901325	-0.5423752	-2.402800	60	SOWAHC BDNF FOSL1 CDC42EP2 CLCF1 HBEGF NDEL1 MCL1 FOXC2 MAP2K3 ARRB1 SNAI1 BIRC2 PLAUR CDKN1A CXCL2 MATK MAFF AREG TNFRSF10B RUNX3 MARC2 IRS2 TAGLN JUND GEM IER5 EPHA2 CYTH1 HNRNPH1 PUS3 DUSP6	down	***
GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN	0.0000000	0.0000000	0.9325952	-0.4532655	-2.402553	181	SLC31A2 PNPLA6 KLF13 MNDA PTPRE RTN3 C5AR1 TBC1D2 NCF2 SLC11A1 LILRB3 ANXA1 SLC7A7 ASAH1 CLEC7A IFI30 PICALM KLF10 CD93 GRN SRGN TCF7L2 RAB14 ZMIZ1 DUSP3 PPT1 SDCBP CASP1 VASP TPP1 PLBD1 LY96 CTSD VIM ID2 FCER1G EVI2A GCA HEXB HCK VAMP3 SGK1 PGD MTMR14 RAB31 KCTD12 TYROBP RHOG IFNGR1 CSTA SERPINB6 RPS6KA1 TNFRSF10B TNFSF13 ATG3 RIN2 TIMP2 ATP6V1A ATP6V0C ATXN1 LGALS3 RXRA ARRB2 SEMA4A RTN4 CDC42EP3 S100A4 GLRX2 SNAP29 THEMIS2 CREG1 RNH1 FEZ2 LYZ CSF2RB TMEM50A DUSP6 SVIL HIPK1 ITGAL FTL S100A8	down	***
PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN	0.0000010	0.0000373	0.6435518	-0.6167305	-2.400217	36	ADCY9 EMP2 HSPB1 PRELP JAM3 TNS1 CPED1 GRK5 KCNMB1 DSTN MYH11 PTGIS CRIM1 RASL12 PKIG MYLIP ID4 SYNPO2 RABGAP1 PKD2 SOD3 LMOD1	down	***
GSE18893_TCONV_VS_TREG_24H_TNF_STIM_UP	0.0000000	0.0000000	0.9653278	0.5331962	2.398868	164	HELLS TICRR TROAP CCDC34 C21orf58 CMTM1 PRIM2 BRCA1 DEPDC1B CDCA7 GINS1 RACGAP1 SLC27A2 PTTG1 CDC6 FIGNL1 UHRF1 MCM4 MCM2 CDC25A MYBL2 CCNF RCCD1 COQ3 CDT1 RANBP1 NUDT1 C19orf48 KIF15 KNTC1 NUP155 POLA2 MCM7 TTLL12 CDCA5 PRKDC CHAF1B ACTL6A RAD51AP1 SPC24 BRIP1 CAD ETFA COQ9 PSRC1 CKS1B FAHD2A CENPJ GMNN GOT2 E2F1 TRAP1 SAPCD2 ETFB DDT RTCB RNASEH2A CHCHD2 ILF2 CDC23 GSS NMRAL1 SLC37A4 C1orf131 CHTF18 ESCO2 MRPL4 PKP4 BCL2L12 POLD1 CABLES2 VPS25 DCUN1D5 WDR34 PPCDC MRPL41 GINS3 LSM4 ERGIC3 CBR1	up	***
MORF_BUB1	0.0000000	0.0000010	0.7337620	0.6643178	2.396354	42	FOXM1 BUB1B CCNB1 NDC80 KIF14 PLK1 ESPL1 TPX2 SRPK1 XPOT ZWINT HMMR BUB1 CCT5 KIF2C KIF11 SSBP1 GOT2 PMEL SPAG5 VBP1 DLGAP5 TYRO3 MCM6 SRSF1	up	***
CHUNG_BLISTER_CYTOTOXICITY_DN	0.0000017	0.0000588	0.6435518	-0.5913569	-2.393720	39	MNDA PRAM1 FBXO3 C12orf76 FOXP1 KIAA0513 SELL GCA SNN MTPN SNAP23 RGS18 CSTA PLCG2 BIN2 PDLIM1 KAT2B RBL2 FKBP1A CDC42EP3 P2RX1 GRB10	down	***
GNF2_CKS1B	0.0000000	0.0000022	0.7195128	0.6895578	2.393255	36	TRIP13 KIF20A NDC80 GMPS ASPM CDCA8 AURKB ESPL1 TPX2 NCAPD2 RANBP1 MELK BUB1 KIF2C KIF11 MCM3 CKS1B ASF1B BIRC5 ATIC PA2G4 RNASEH2A CDC20 MCM6 CCNA2 SMC2 CENPE PAICS UBE2C	up	***
GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP	0.0000000	0.0000000	0.9214260	-0.4499220	-2.392226	175	SLC31A2 USP12 ZC3H12C CLDND1 TMOD3 CORO1C GPCPD1 CDC42 WBP4 SNHG5 EIF4A1 CHMP1B EIF1 SDE2 AHRR CSGALNACT2 ZBTB21 PTX3 BFAR RGCC NFE2L2 NDEL1 BTG3 PPP3CC ZMIZ1 PLAUR MAP1LC3B SEC24B PER2 LRRC40 ATF3 ID2 CCL4 MAFF RSRC2 ZDHHC20 CLN8 SERTAD2 MCMBP PPIL4 CREBRF SGK1 NEK7 ETV3 JUN ARL5B PTGER4 REL TAGLN2 GAS2L3 AGFG1 RRN3 CDK17 PPTC7 MAPK8 SAV1 EHD1 ZBTB1 ZFAS1 DUSP5 EWSR1 ZNF136 MAP3K2 PPIL3 LGALS3 TOB1 GNA13 ZNF267 CTTNBP2NL SERTAD1 RAB5A CDC42EP3 LRP12 BRWD1 KPNA4 MAFK DNAJB9 CYTH1 NAA15 C1orf52 CNOT8 SPATA5L1 EHD4 TRIM36 MED17 PIM3	down	***
PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_UP	0.0000003	0.0000140	0.6749629	-0.5604649	-2.392106	51	ACP5 SLC39A8 FUCA1 LAMP1 PLA2G7 ATP2B1 GM2A IFI30 RGCC GRN SRGN MPEG1 DAB2 RBMS1 CXCL2 PLEKHB2 NCKAP1L SGK1 CTSS RAPGEF1 SIGLEC15 TRAK2 SOD2 MS4A4A GLUL SAMSN1 CREG1 PAPSS2 CSF2RB DUSP6	down	***
GNF2_CD7	0.0000010	0.0000381	0.6435518	-0.6227173	-2.391878	35	CTSW GIMAP6 CCL4 XCL2 PRF1 KLRD1 CD160 KLRB1 IL2RB PTGER2 CD7 TBX21 CST7 RUNX3 NKG7 IL18RAP KLRK1 RORA KLRF1 PRKCH ITGAL	down	***
GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.0000000	0.0000001	0.7881868	-0.4802116	-2.391146	106	ANGPT4 ACVRL1 HMOX1 SOX18 PPARG ADTRP GATA2 EMP2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 ADAM17 CLEC14A HSPB1 NR4A1 RGCC NFE2L2 AKT3 FOXC2 MAP2K3 STAT5A AMOTL1 KLF4 THBS1 MIR24-2 PIK3C2A NUS1 SRF PRCP NOTCH1 ETS1 RHOJ TGFB1 MIR23A MIA3 FGF2 VASH1 EPHA2 FGFR1 STARD13 GREM1 ITGB1 MIR640 MIR2355 EFNB2 ANGPT2 HMGB1	down	***
REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION	0.0000001	0.0000041	0.7049757	-0.5555946	-2.390443	54	LYL1 EGR2 FOSL1 MEF2A TRIB1 DUSP3 REST ID3 ID2 ARC SRF RPS6KA2 ID4 PPP2CA SGK1 JUNB CREB1 RPS6KA1 FOS FOSB PPP2CB NAB1 JUND VGF DUSP7 EGR1 DUSP6 ATF2 MAPK1 EP300 MEF2D MAPK7	down	***
MODULE_397	0.0000000	0.0000000	0.8513391	0.5573580	2.388076	108	TRIP13 DDX11 FOXM1 CDC45 BUB1B EYA2 CENPF CIB2 NDC80 CABIN1 NOL12 IGFBP6 BAIAP2L1 PLK1 NUF2 PTTG1 TPX2 HOXB7 MYBL2 ORC1 GON4L SRPK1 NCAPD2 ZNF74 KIF23 AURKA FGG CDCA5 ANKEF1 KIF11 GPSM2 SALL2 ASF1B DNAH6 GMNN E2F1 TRAP1 NUP205 RAB6B FER1L4 IGSF3 GRAMD1A ARHGEF16 ALDH7A1 EFCAB2 SNRPA RAD51D JMJD4 NT5M CDC20 WDR34 RPUSD1 NOL6 ZNF432 PYGO2 CACNB3 TRIP6 GRAMD1B ARHGAP11A SMC2 BCAS3 CENPE CDC25B EPHB4 MRPS26 NCAPH F5	up	***
PID_IL12_STAT4_PATHWAY	0.0000040	0.0001289	0.6105269	-0.6394252	-2.388006	30	PPP3CA IL18R1 PRF1 CD80 JUN STAT4 TBX21 FOS MAPK8 TGFB1 CD86 PPP3R1 IL18 IL18RAP CREBBP CD3G PIAS2 HLA-DRB1 CD3E IRF1 CD4	down	***
GO_NEGATIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.0000032	0.0001057	0.6272567	-0.6375721	-2.385310	31	ANGPT4 ACVRL1 PPARG TBXA2R RHOA MIR146A MMRN2 RGCC KLF4 THBS1 MIR24-2 NOTCH1 TGFB1 FGF2 VASH1 STARD13 MIR640 MIR2355 ANGPT2 HMGB1	down	***
GSE16266_CTRL_VS_LPS_STIM_MEF_UP	0.0000000	0.0000000	0.9214260	-0.4488858	-2.384441	179	SMAD6 LPIN2 HMOX1 SWAP70 OLR1 DLC1 TMEM52B ENG COQ2 BMPR2 INPP5A MEF2A IER2 ZBTB4 SLC7A7 ITGA5 KLF10 CD58 ZMIZ1 MOAP1 LIMS1 SLC46A2 ZSWIM6 REST ID3 THBS1 CEBPA DENND3 FMNL3 SSH1 KCNMB1 ID2 ARAP3 DUSP1 ELK3 SMAD7 GPR157 RASGEF1B BTG1 SPIN1 RYBP SLCO2B1 NOTCH1 DESI2 PLK3 JUNB DNASE2 SKIL IDS MORC3 GPRIN3 CDK17 RUNX3 TFEB ZRANB1 TGIF1 KCTD10 MAP3K2 GNB4 STK40 GNA13 PLEKHO2 SLC43A2 VASH1 MIR155HG SERTAD1 CEP170 ITPRIPL2 CALHM2 BLOC1S2 CXCR4 HAVCR2 PSME4 ISCU NFKBIA SIGLEC9 SKI TMCC3 GRB10 TRIM36	down	***
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN	0.0000000	0.0000000	1.0864405	-0.4311253	-2.379088	282	CD52 RDX GPR65 FYN CTSW ZCCHC2 IDI1 CIR1 CDC42 TGFBR3 EOGT USP47 TGFBR2 ABCB1 CD8A HEG1 GGA2 PTPRM UBL3 CACNA2D2 SERINC1 LUZP1 TOR1AIP1 ADRB2 IL18R1 SLC25A37 CRTAM SRGN CD58 PPP3CC TIPARP EVI2B SRSF5 CASP1 ACSL3 LEPROTL1 ARNTL PTPRC HOPX ID2 CCL4 CEP57 ZBTB43 SS18L2 PRF1 EPS15 CCSER2 KLRD1 CUL5 TBC1D4 DEGS1 USP16 CDKN2AIP NCOA1 ARL6IP5 CREM CD160 KLRB1 PHACTR2 IL2RB CD48 STAT4 ARHGEF10 MTMR9 MCM9 PIK3R1 THUMPD1 IDS MALT1 ENTPD4 TBX21 CEBPZ CST7 ZBED5 SNRK NDUFV2 CALM1 MBP NKG7 TRAPPC10 WHAMMP3 BCAS2 GSAP NR2C1 DUSP5 CNOT7 ATXN1 HNRNPH3 THAP11 ANKRD12 N4BP2L2 CLEC2B PDE4B GTF2B SYT11 HAUS3 INTS6 PCM1 RTN4 IQSEC1 TIAM1 TAB2 PSME4 RBM48 NPAT ANKRD49 B3GNT2 MTUS1 RORA NR3C2 MT2A LPAR6 USP48 PMAIP1 ACAT1 MED17 KLRF1 HAT1 ICOS PPWD1 MICAL1 GNG11 GPR137B DAPP1 ZNF14 CTR9 MAN1A1 TES CUL2 RCBTB2 TAF1D FCHSD2 NKTR APOBEC3C DERL2 CFLAR PJA2 GZMB TPST2 SLC25A28 KLRC1 MT1X	down	***
NADERI_BREAST_CANCER_PROGNOSIS_UP	0.0000001	0.0000029	0.7195128	0.6553061	2.378154	43	KIF20A TIMELESS UBE2T NDC80 RACGAP1 FA2H ASPM CDCA8 PTTG1 UHRF1 MYBL2 SHMT2 MELK EXO1 CEP55 BUB1 CDCA5 IL20RB RNFT2 SOX11 DSCC1 SPAG5 FADD TRIM24 POLD1 PSMD2	up	***
NIKOLSKY_BREAST_CANCER_7P22_AMPLICON	0.0000001	0.0000070	0.6901325	0.6867793	2.372607	35	SLC29A4 IQCE EIF3B INTS1 MICALL2 NUDT1 BRAT1 TMEM184A GPER1 MAD1L1 WIPI2 GPR146 GET4 C7orf50 COX19 CYP2W1 TTYH3 SUN1 ADAP1 AP5Z1 PSMG3 TNRC18 FOXK1	up	***
MODULE_158	0.0000000	0.0000020	0.7195128	0.6702414	2.368469	39	DDX11 CDC45 CENPF PRIM2 POLE ORC1 CHAF1A TOP2A POLD2 RRM2 MCM3 CHAF1B LIG1 TOPBP1 BLM SSBP1 POLE2 GMNN FEN1 RNASEH2A POLD1 CDC7 RPA1 MCM6 PRIM1 RFC5 CENPE	up	***
AMIT_DELAYED_EARLY_GENES	0.0000070	0.0002039	0.6105269	-0.7376069	-2.368049	18	FOSL1 BTG2 KLF10 KLF6 RBMS1 ATF3 HES1 MAFF PIAS1 CREM JUNB	down	***
WILENSKY_RESPONSE_TO_DARAPLADIB	0.0000120	0.0003250	0.5933255	-0.6817038	-2.367375	23	IL1A HMOX1 PLA2G7 GM2A LAIR1 EVI2B PTAFR PLAUR EVI2A CTSS CD48 BIN2 CCR1 ARRB2	down	***
WONG_EMBRYONIC_STEM_CELL_CORE	0.0000000	0.0000000	1.1512205	0.4956850	2.366292	303	TRIP13 HELLS KIF20A RUVBL1 AK4 ELOVL6 CHEK2 BUB1B NUP107 PROM1 NEK2 SOX2 SLC2A1 THOC3 NDC80 PRIM2 CDCA7 TTK CDK4 RACGAP1 GTSE1 NIPSNAP1 PLK1 CDCA8 AURKB CDC6 E2F3 CCNB2 MCM4 MCM2 MYBL2 GLDC ORC1 CCNF ALDOC DTL NCAPD2 COQ3 LSM5 RUVBL2 NDUFB8 EXO1 CISD1 KIF23 CHAF1A MRPL15 BUB1 EEF1E1 TOP2A CCT5 AURKA CBX3 NDUFS2 MCM7 RRM2 CDCA5 WDHD1 KIF11 MCM3 LMNB1 CHEK1 MAD2L1 FBL GNPDA1 ETFA RAD18 IPO9 BLM MRPS30 PHB UQCR11 PARP1 CKS1B NUSAP1 MRPL37 CDK1 POLE2 BIRC5 GMNN POLR3K PSMB5 MRPS2 SPAG5 NLN NOP2 PA2G4 EIF6 DNMT1 VBP1 DPP3 DLGAP5 NDUFA11 PSMA5 PUS1 ALDH7A1 SNRPA KIF22 MRPL11 MAPK13 DTYMK HDAC1 MRPL4 ANP32E DAP3 POLD1 CDC7 GEMIN6 TIMM13 CDC20 STOML2 POP7 FAM136A UBE2V2 PRMT1 CKAP2 MCM5 SNRPD1 RCC1 PDIA4 LSM4 NT5DC2 EIF3K RAB34 FARSA GLO1 MSH2 CCNA2 PRIM1 BANF1 NME4 WDR77 COX5B TRIP6 ECHS1 GNA14 SMC2 TP53 TIMM44 APEX1 ENO1 NDUFB7 ACAD8 BRIX1 NCAPH GEMIN2 LYPLA1 RCN2 MRTO4 PLK4 UTP18 MRPL12 ADSL CLPP	up	***
APPEL_IMATINIB_RESPONSE	0.0000056	0.0001713	0.6105269	-0.6323921	-2.361740	30	ACP5 PPARG ENG C5AR1 FUCA1 LAMP1 LILRB3 APOD ASAH1 GM2A APOC1 MSR1 CTSD HEXB CTSZ	down	***
LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN	0.0000000	0.0000001	0.7881868	-0.4694866	-2.358903	118	SLC31A2 DPYSL2 LINC00472 LMO2 PSMD5 TMX4 PBX3 ANXA5 RAB14 RHOB CYBRD1 PER3 SDCBP AOC3 AFAP1L1 DAB2 ZFAND5 CLIC4 UBQLN1 ERP44 UBE2E2 CD302 EVI2A GNAQ BACE1 VCPKMT TMOD1 SGK1 SOCS3 PPP6C MT1L CCDC50 AK1 RCAN1 GLIPR1 CELF2 TGFB1 CTNNAL1 GABARAPL1 RIMKLB MBNL1 BMP2K MS4A4A ALDH2 ISCU OSER1 RASSF8 RNF38 DNAJB9 MT2A TOX2 LYZ SLFN11 SETX PSIP1 CFL2 TGOLN2 FBXW2 ALG2 MSANTD3 MT1E TES NFIL3 DUSP22 MYO5A MT1X GSN SON C3AR1 ISCA1	down	***
SWEET_LUNG_CANCER_KRAS_DN	0.0000000	0.0000000	1.1421912	-0.4113556	-2.354750	349	SMAD6 EPAS1 PRX ACVRL1 SC5D SASH1 FOXF1 TEK ACE EDNRB RASIP1 TBX3 IL1B MNDA CLEC3B TIE1 LYVE1 EMP2 GREM2 CYP4B1 RAMP2 THBD PTPRB CDH5 ENG BDNF LYL1 FYN EMCN LMO2 SOX17 CCRL2 KANK3 CAV1 CALCRL QKI INPP5A MSLN SPCS3 NUMB TBX2 LTBP4 TM2D3 LIFR LATS2 PAG1 MS4A1 ADRB2 CD93 SPTBN1 CES1 ZEB1 SRGN TFRC KRT4 RHOB ADARB1 CFD ARRB1 TNNC1 RAB12 AHNAK SORBS1 NPNT KLF4 PEG3 ID3 KLF9 ANKRD10 TJP1 CLDN5 GRK5 KLF7 MYO1B CLIC4 NPR3 CADM1 HOPX RECK IGFBP2 SHE EPS15 DUSP1 MYH11 PTGIS PLAC9 VWF SIAH1 HCK VAMP3 SCEL FLT1 METAP1 JUN SH3BP5 INMT KCTD12 ETS1 CYP2A6 RHOJ FERMT2 ACKR3 GMFG PRKCE NDST1 CDK14 ACSL1 KLF2 BCL6B ICAM2 PKD2 SLC4A5 PKIA TCF4 PDLIM1 GNB4 MEIS1 MACF1 RGS2 SPOCK2 TAGLN ETS2 SOD3 SESN1 GPX3 SPARCL1 TFPI SCN7A SPIB MS4A4A TIAM1 CXCR4 CDKN1C MFAP5 PTCH1 POLR2M GLUL LIMCH1 NFKBIA KIT TIMP3 EDN1 COL13A1 GIMAP4 FEZ2 PAPSS2 PPP1CB MAP4 PSIP1 KALRN PPP2R3C	down	***
GSE22886_NAIVE_CD4_TCELL_VS_DC_DN	0.0000000	0.0000000	0.8986712	-0.4435788	-2.352518	182	SLC31A2 ACP5 STAC MNDA LIPA FLVCR2 ARL8B PRKAR1A NCF2 AVPI1 SPG21 MAN2B1 CLEC7A IFI30 ANXA5 NFE2L2 GRN LAMTOR3 ATP6V1B2 CD58 CST3 ZMIZ1 MTMR6 DUSP3 PPT1 SDCBP LIMS1 YBX3 SLC7A8 CEBPA ATP6V1D CLIC4 LY96 ITGAX VIM M6PR TM6SF1 PLEKHB2 ZMPSTE24 HTT TM9SF2 CALM2 PI4K2A GLB1 VAMP3 PSEN1 PGD RAB31 ATP6V0B CYCS IFNGR1 CSTA TBC1D12 STX7 ZNF804A SNX1 PLCG2 CD74 GNG5 EXOC1 CCR1 FCGRT NPTN CLASP2 ZNF267 RXRA OPN3 MGAT2 DAPK1 STAM2 GLRX2 CTSC SNAP29 CREG1 WDFY3 RNH1	down	***
GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN	0.0000000	0.0000000	0.9545416	0.5196337	2.350927	173	TRIP13 FOXM1 KIF20A FAM81A TICRR PARPBP MCM10 NEK2 XYLB CENPF TG MND1 PBK KIF18B DEPDC1B TTK RACGAP1 E2F8 ANLN GMPS ASPM STIL PLK1 NUF2 CDC6 TPX2 E2F3 CCNB2 FIGNL1 UHRF1 SPATS2 MYBL2 CCNF DTL MELK EXO1 CEP55 BUB1 TOP2A AURKA IFT43 KIF2C POC1A CLSPN CXCR5 MMS22L CDCA5 KIF11 FANCD2 CDC25C LIG1 CHEK1 AHCY RAD51AP1 SPC24 PERP CKS1B CDKN2C C12orf75 NUSAP1 PLOD2 CDK1 BIRC5 ARPC1A GMNN DNA2 FEN1 LRRC42 RECQL4 CCNE1 TUBG1 FAH ALDH7A1 SNRPA KIF22 MFSD2A ESCO2 SAP30 FBXO44	up	***
GO_CELLULAR_RESPONSE_TO_LIPOPROTEIN_PARTICLE_STIMULUS	0.0000095	0.0002663	0.5933255	-0.6399382	-2.347257	28	PPARG ADTRP LPL CDH13 MYD88 CD9 CD36 MIR146A ADAM17 ABCG1 SOCS5 TLR4 FCER1G MIA3 CD81 SREBF2 LDLR HMGCS1 ITGB1	down	***
CHEN_LVAD_SUPPORT_OF_FAILING_HEART_UP	0.0000000	0.0000012	0.7337620	-0.4925740	-2.346395	88	CSDC2 CYP4B1 TXNIP TMEM204 BTG2 RGCC TCAP MCL1 CNN1 TIPARP NES KLF9 ZFAND5 DOCK9 CDKN1A ATF3 PER1 MAPRE2 PDK4 ELF1 AREG JUN PIK3R1 MFAP4 FSTL3 KLF2 FOXO3 FLNC CDC37L1 IRS2 AMD1 IER5 CEBPD DIXDC1 MT1M METTL7A GLUL NFKBIA TIMP3 SYNPO2L MT2A DNAJB5 SERPINE1 ZBTB16 SLC38A2 ZFP36 MT1E NFIL3 SH3BGR PLA2G5 MT1X CDC42EP4	down	***
GNF2_SMC2L1	0.0000001	0.0000039	0.7049757	0.7005712	2.344495	32	FOXM1 CENPF KIF18B NDC80 TTK ASPM CDCA8 ESPL1 CCNB2 MYBL2 ZWINT HMMR BUB1 TOP2A KIF11 MCM3 CKS1B NUSAP1 CDK1 BIRC5 CDC20 MCM6 CCNA2 PRIM1 SMC2 CENPE	up	***
GNF2_STAT6	0.0000003	0.0000116	0.6749629	-0.5213206	-2.343952	64	LRRFIP1 MYD88 LCP1 EVI2B BNIP2 OSTF1 LAPTM5 SELL ACTR3 CD53 MBD2 CMTM6 ARHGDIB ACTR2 EMP3 SNAP23 CD48 RAC2 JUNB CAP1 MOB1A TGFB1 ADPGK ARPC2 ACAP2 ICAM3 ARPC5 PAK2 ANXA11 DAZAP2 IQGAP1 CYBA FXYD5 CAPZA1 SERP1	down	***
GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN	0.0000000	0.0000000	0.8753251	-0.4472588	-2.343083	157	SCN4A OLR1 NUP54 RAPGEF2 PTPRE CD44 HCAR2 CCRL2 MYD88 AGPAT4 IGSF6 CCNL1 RBM7 SBDS SDE2 BTG2 FOXP1 TREH CLN5 NFE2L2 TFEC AGO3 MEFV PTAFR PLAUR TNFSF15 KLF7 NFKB1 IRAK2 CCL4 PNRC1 PLEK DSE PIK3R5 NCKAP5 IKZF5 LMBRD1 FAM102B HCK NINJ1 MITF PTGER4 SKIL MALT1 RC3H1 GRIA1 REL BTBD7 EHD1 GSAP KCNA3 GNA13 PDE4B GTF2B RNF2 ICAM1 NLRP3 CCR9 MEX3C TRAF1 RND1 NFKBIA EDN1 DOCK10 MCOLN2 SAMSN1	down	***
GNF2_RAB7L1	0.0000086	0.0002457	0.5933255	-0.6319362	-2.341439	29	GPR65 CTSW GNPTAB CCL4 PRF1 KLRD1 IL2RB JAK1 PTGER2 RUNX3 NKG7 BIN2 GSAP CYTH1 KLRF1 PRKCH TES CYTIP GZMA STK10	down	***
GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN	0.0000000	0.0000000	0.8986712	-0.4400620	-2.340033	176	ACP5 CD52 SLC12A6 MNDA CCDC88A MYADM CITED2 BMPR2 MANBA CD9 FUCA1 AVPI1 TXNIP DPEP2 NCEH1 MCTP1 CD5 SIRPB2 ASAH1 ITGA5 LITAF TTYH2 RNASE1 LAIR1 RGCC NFE2L2 GRN SPTBN1 ZFYVE16 SORBS3 ZMIZ1 CPED1 MSR1 CYBRD1 ARRB1 AHNAK SDCBP CPVL ITM2B RRM2B ID3 TPP1 PLBD1 TMBIM1 TLR4 LBH ARHGAP9 PRCP PDK4 ELF1 CTSS NEK7 UTRN AQP3 MITF GCNT4 TPP2 SIGLEC1 TIMP2 RGS2 BNIP3L RTN1 ARRB2 IQSEC1 ESYT1 NLRP3 METTL7A DAPK1 ANXA11 CAMSAP2 CREG1 TLK1 IL16 LYZ ARRDC2 MDS2 CLEC4E C5 ZYX	down	***
HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP	0.0000000	0.0000000	0.8753251	0.5309800	2.337235	132	TRIP13 HELLS KIF20A HJURP CDC45 MCM10 NEK2 COIL CCNB1 UBE2T NDC80 TTK RACGAP1 E2F8 ANLN AURKB CENPA ECT2 CCNB2 PRC1 ACY1 SPDL1 MELK KIF23 MKI67 BUB1 TOP2A CENPL AURKA KIF2C RRM2 CDCA5 WDHD1 RAD54L CHAF1B CDC25C LIG1 DCTPP1 PIH1D1 INCENP CKS1B CDKN2C NUSAP1 CBX5 CDK1 DNA2 FEN1 SSX2IP CBX1 VPS72 DNMT1 CCNE1 DLGAP5 KIF22 TK1 ANP32E CKAP5 CDC20 RPA1 MCM6 HAUS6 MYEF2 NT5DC2 CCNA2 RFC5 RAD51	up	***
MODULE_125	0.0000001	0.0000039	0.7049757	0.6586616	2.336913	40	DDX11 CDC45 CENPF PRIM2 POLE ORC1 CHAF1A TOP2A POLD2 RRM2 MCM3 CHAF1B LIG1 TOPBP1 BLM SSBP1 POLE2 GMNN FEN1 RNASEH2A POLD1 CDC7 RPA1 MCM6 PRIM1 RFC5 CENPE	up	***
GNF2_FGR	0.0000117	0.0003175	0.5933255	-0.6414542	-2.334587	27	LILRB3 FGR IFI30 CASP1 COTL1 FCER1G CMTM6 HCK CTSS TYROBP RHOG RGS2 S100A4 THEMIS2 SH3BGRL3 AOAH TNFRSF1B PYCARD TMEM127 FGL2	down	***
MORF_BUB1B	0.0000001	0.0000034	0.7049757	0.6091616	2.330500	54	TRIP13 BUB1B NDC80 TTK KIF14 PLK1 CENPA ESPL1 TPX2 MCM2 SRPK1 SHMT2 ZWINT HMMR BUB1 TOP2A CCT5 PRKDC RAD54L ACTL6A CDKN2C CDK1 GOT2 DNMT1 ANP32E KIF20B TYRO3 CDC7 MCM6	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP	0.0000125	0.0003385	0.5933255	-0.6402797	-2.330312	27	LINC00622 LATS2 KLF6 CSRNP1 ZSWIM6 MAFG RIT1 MAFF DNAJA1 PPP1R15A PTP4A1 KIAA0232 ZNF844 C16orf72 GABARAPL1 ABL2 FBXO30 HSPA8	down	***
LIAN_LIPA_TARGETS_3M	0.0000015	0.0000535	0.6435518	-0.5496991	-2.329516	50	CXCL3 ACP5 HMOX1 MS4A7 FCN1 SLC15A3 MARCO SLC11A1 IGSF6 LILRB3 PLA2G7 MSR1 MPEG1 ATP6V0D2 FCER1G MMP19 KLRB1 UTRN C1QA CSTA	down	***
GNF2_CD14	0.0000092	0.0002601	0.5933255	-0.6226917	-2.325513	30	FCN1 STX11 LILRB3 CD33 SLC7A7 IFI30 CD93 PLBD1 CD302 DUSP1 HCK CTSS HK3 TYROBP CD1D RGS2	down	***
HALLMARK_GLYCOLYSIS	0.0000000	0.0000000	0.9325952	0.5140026	2.322494	172	GPR87 KIF20A BIK EGLN3 PKP2 AK4 CHST6 PPFIA4 DDIT4 CHST4 DEPDC1 TFF3 GAL3ST1 B3GAT1 EFNA3 ANKZF1 CENPA SOX9 STC2 DPYSL4 COPB2 B4GALT4 HMMR GFPT1 TPBG AURKA PKM ANG FAM162A EGFR B3GNT3 ABCB6 PFKP B4GALT7 GNPDA1 NOL3 ALDOA CLDN9 SLC25A10 CASP6 PLOD2 CDK1 MERTK GOT2 RBCK1 POLR3K ALDOB SLC25A13 KIF2A ARTN PSMC4 MPI GALK2 AGL ALDH7A1 XYLT2 COG2 SLC37A4 SRD5A3 SAP30 CHPF P4HA1 TSTA3 KDELR3 GMPPA MED24 SLC35A3 HAX1 LHPP SPAG4 ME1 HDLBP HK2 ZNF292 PAXIP1 PGAM1 CHPF2 GNE ALG1 BPNT1 IDUA PPIA ENO1	up	***
MORI_IMMATURE_B_LYMPHOCYTE_UP	0.0000049	0.0001518	0.6105269	-0.5683281	-2.322266	41	GPR65 SAMHD1 GPCPD1 GGA2 IFI30 MS4A1 MCL1 LIMS1 PTPRC HCK BTG1 CTSS ATP6V0B CD83 PXK RHOQ MYL12A CD74 IGKV1D-39 PIP4K2A CNR2 DUSP6	down	***
GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN	0.0000000	0.0000000	0.9653278	0.5066900	2.321258	188	TRIP13 LINC00342 FOXM1 CDC45 BDH1 BUB1B CCNB1 CENPF TIMELESS FAM153B TTF2 NDC80 PRIM2 PHGDH TTK GINS1 CDK4 GTSE1 SLC27A2 GMPS POLE STIL CENPA ESPL1 CDC6 TPX2 UMPS GLDC ZWINT NME1 RANBP1 MELK HMMR EXO1 NUDT1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A CCT5 NUP155 KIF2C AKAP1 KIF11 GPSM2 CDC25C LIG1 CHEK1 AHCY PKMYT1 BLM SKP2 CKS1B EFCAB11 TMEM106C CDK1 POLE2 ATIC OAT NPM3 UNG TRAP1 SPAG5 ETFB LAPTM4B RNASEH2A NET1 FANCG CCNE1 TUBG1 DLGAP5 GSS ALDH7A1 SLC37A4 TK1 DTYMK ANP32E KIF20B	up	***
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_DN	0.0000000	0.0000000	1.0476265	0.4899864	2.319794	271	ATP10B CCNO SAA1 LTF ALDH3B2 PRR15 RIBC2 ABCA13 MUC13 ADH1C DNAH2 CHST6 PROM1 ARMC3 PTPRN2 MUC4 WFDC2 TOX3 MUC16 TTC25 CCDC113 TFF3 FANK1 CCDC74A LCN2 ALDH1L1 SLC27A2 RHOV DAW1 SPAG17 AGR2 CIB1 MUC20 VILL DNAI1 TJP3 RSPH1 ARMC4 C9orf116 FOXJ1 TSGA10 BPIFB1 IQCD PSENEN SLC2A10 P4HTM HYDIN WDR78 SPEF2 TEKT2 FAM216B SRGAP3-AS2 CCDC114 C7orf57 WDR66 NEK11 PDZK1IP1 ASS1 IFT172 BACE2 SPATA17 CAPS FUT2 MGLL TTC9 DRC1 DNER DMKN TNFRSF21 MDH1B WDR54 FAM81B SPAG6 KLHDC9 NEK5 EFCAB1 TRIM7 KIAA1211L AK7 DNAH5 TMEM231 CASC1 TSPAN1 PIAS3 DNAH7 SPATA18 EFCAB2 TUBB2A FAM166B IQCG FBXO15 MORN2 S100A9 SPAG1 SPA17 SMIM22 AHNAK2 EPB41L4B TRAF3IP1 AGBL2 EFHC1 RSPH10B CXCL1 UPK1B EML6 ODF3B VWA3B DNAI2 EFHB KATNB1 RSPH4A TMEM45B B9D1 LRP11 C19orf33 TTC12 TMC5 SYBU CCDC181 TUBA4B ENKUR TCTEX1D1 TRAK1 LRG1 CGN UBXN10 ALOX15 CAPN9 CLDN10 MUC1 MAP3K19 NQO1 TEX9 SPATA33 ARMC2 MORN3 DNAAF1 TEKT1 WDR63 ST6GALNAC1 ROPN1L TMPRSS4 RALGPS2 PTGR1 AK9 TCEA3 SNTN TPPP3 OSCP1 C1orf194 ELL3 TPPP VWA5A S100P CCDC65 C5orf49 DNAH9 FMO5 PACRG PIFO	up	***
DIRMEIER_LMP1_RESPONSE_EARLY	0.0000008	0.0000312	0.6594444	-0.5313611	-2.318830	58	INSIG1 EGR2 BCL2A1 IER2 MAN2B1 EIF1 BTG2 KLF6 LCP1 MCL1 CCL3 CCL4 JUN JUNB PPP1R15A ACKR3 CD83 GPR183 DUSP5 JUND ICAM1 ACTB TRAF1 NFKBIA TNFSF9 HERPUD1 EGR1 HMGCS1 ZFP36 PIK3CG CD69	down	***
GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN	0.0000000	0.0000000	0.9214260	-0.4340567	-2.318193	191	SLC31A2 LPIN2 FABP4 SNX10 BMP2 EGR2 OTUD1 PDE1B CITED2 SLC15A3 BCL2A1 IL1RN IGSF6 IER2 CCNL1 RBM7 HBEGF ADAM17 SDE2 BTG2 SLC7A11 CLN5 PPP2R2A NDEL1 SLC25A37 TFEC SRGN MCL1 TIPARP SLC7A2 IL10 MAP2K3 CSRNP1 STAT5A RAB12 AHNAK AOC3 PLAUR COQ10B ID3 VASP STX3 SOCS5 KLF7 CLIC4 CXCL2 ATF3 IRAK2 C9orf72 GSDMA ID2 DUSP1 SPRYD7 USP16 PTH1R RPS6KA2 AREG KCTD12 DENND4A CLN3 SLC3A2 CD74 IRF5 GNA13 GTF2B VASH1 NLRP3 TBC1D1 KATNA1 EDN1 B3GNT2 MCOLN2 TLK2 MT2A DNAJA2 CSF2 SLC16A10 HERPUD1 EGR1 SERPINE1 ZNF800 HIPK1 DCUN1D3 ZFP36 CD69 SERP1 IRF1 NFIL3 HIVEP1 IRF4 EBI3 DUSP2 C15orf48 SENP6 ST3GAL1 SLAMF7 FEM1C TANK	down	***
GSE43863_DAY6_EFF_VS_DAY150_MEM_LY6C_INT_CXCR5POS_CD4_TCELL_DN	0.0000000	0.0000000	0.8753251	-0.4374610	-2.315183	172	GCOM1 SLC12A6 PECAM1 LRRC8C PTPRE TUBB1 CTSW TBXA2R CBL PPM1D PDE2A SEMA6D C1orf21 ABCG2 CYB561A3 TMEM123 AKT3 FLI1 CCDC82 MPEG1 TCP11L2 STK17B DENND3 LAPTM5 PDE3B SELL HPSE KLRD1 N4BP2L1 AFF1 ARHGDIB HEXB EMP3 MYLIP CREBRF S1PR4 CTSS HCST ETS1 MSRB3 TYROBP GMFG FRYL N4BP3 LPCAT2 AP3B1 RASSF2 IP6K1 KLF2 C19orf38 CD1D DCK BAZ2B SERINC3 HELZ JUND BMP2K SELPLG BNIP3L CDC42EP3 SSH2 ABI3 CD3G CYTH1 CCND3 LPAR6 CNN2 BANK1 ARHGEF18 CDON CNR2 LNPEP PLEKHA2 RNF167 PIK3CG SIGLEC10 MAP4K2 RCSD1	down	***
REACTOME_NGF_STIMULATED_TRANSCRIPTION	0.0000016	0.0000569	0.6435518	-0.6146539	-2.312890	34	LYL1 EGR2 FOSL1 TRIB1 REST ID3 ID2 ARC SRF ID4 SGK1 JUNB CREB1 FOS FOSB NAB1 JUND VGF EGR1 ATF2 EP300 MEF2D	down	***
MODULE_57	0.0000002	0.0000078	0.6901325	0.6081647	2.307829	53	CDC45 CHEK2 BUB1B CCNB1 CDK4 PLK1 PTTG1 ESPL1 CDC6 E2F3 CCNB2 MCM4 MCM2 CDC25A ORC1 BUB1 MCM7 MAD1L1 PRKDC MCM3 CDC25C CHEK1 MAD2L1 MDM2 PKMYT1 CDK1 E2F1 CCNE1 HDAC1 CDC7 CDC20 MCM6 MCM5	up	***
HALLMARK_TGF_BETA_SIGNALING	0.0000023	0.0000776	0.6272567	-0.5419986	-2.305698	52	SMAD6 BMP2 ENG BMPR2 RHOA KLF10 SPTBN1 UBE2D3 ID3 TJP1 THBS1 CDK9 ID2 SMAD7 BCAR3 RAB31 LTBP2 JUNB PPP1R15A SKIL TGFB1 TGIF1 FKBP1A CDKN1C SKI SERPINE1 NOG	down	***
CAIRO_HEPATOBLASTOMA_CLASSES_UP	0.0000000	0.0000000	1.3344975	0.4633739	2.304891	536	HMGA2 TRIP13 KIF20A HJURP RUVBL1 AK4 MCM10 FANCI CHEK2 BUB1B NEK2 COIL SULT1C2 CCNB1 CENPF TIMELESS CPSF6 PSPH GGCT PBK KIF18B NDC80 TBRG4 TTK GINS1 CDK4 KIF14 ASPM TOMM34 PLK1 CDCA8 AURKB CENPA ALDH18A1 ECT2 CDC6 TPX2 CCNB2 MCM4 MCM2 CDC25A PRC1 GLDC CCNF EIF3B DTL CCT6A LIG3 MIS18A GINS4 SRPK1 NCAPD2 MYL6B CDT1 AP1G2 CCT2 SPDL1 NME1 RANBP1 RUVBL2 BZW2 HMMR NLE1 SMARCC1 KIF23 OSBPL2 CHAF1A MKI67 KIF15 MRPL15 KNTC1 BUB1 FANCA EEF1E1 TOP2A CCT5 RFXANK PUS7 AURKA CBX3 WDR3 ODF2 SAE1 SFI1 KIF2C MCM7 MAD1L1 RRM2 PRKDC TRRAP KIF11 MCM3 PLTP CDC25C EMG1 YEATS2 LIG1 CHEK1 DNAJC9 MAD2L1 AHCY FBL RAD51AP1 CAD PHB MNAT1 SKP2 PARP1 DDX56 CKLF NCAPG2 NUSAP1 CDK1 EXOSC2 RFWD3 BIRC5 CCT3 ATIC NPM3 NCAPG TRAP1 PSMB5 SEC61G PRPF6 CPNE1 EZH2 NUP205 POLR1C ACTR3B SPAG5 SF3B3 FOCAD LAPTM4B RNASEH2A DNAJC7 KPNB1 TPD52L2 CHCHD2 DNMT1 ILF2 CCNE1 TUBG1 DLGAP5 PDCD11 TRMU CTSV PUS1 AARSD1 MAN1B1 KIF22 SSRP1 DTYMK MYBBP1A CENPQ GINS2 AGPAT5 TCEA1 KRT19 POLD1 NUP85 AAMP CCT7 SUPT16H PFAS CKAP5 CDC20 STOML2 HMGA1 LRRC59 POP7 FAM136A ACLY MCM6 DNMT3A MRPS33 THOC5 PRMT1 UTP20 HEATR1 TDP1 SNRPD1 LANCL2 SRSF1 C1orf109 AATF CREB3L2 POLR3E RCC1 PDIA4 LSM4 TXNL4A PI4KA NT5DC2 ERGIC3 WDYHV1 TSR1 TCERG1 PRMT5 EPCAM KLHL7 DPH5 FARSA COG5 PMS1 B9D1 ATP6AP1 MSH2 CCNA2 SMARCA4 HDLBP GTF3C2 ABCF2 WDR77 STK25 TPGS2 ZWILCH SUPT3H PAXIP1 SNRNP200 ACP1 AGBL5 CIAPIN1 SMC2 PNKP GMPR2 DNAJC10 GPX7 APEX1 MRPS27 UBE2C GPN1 CDKAL1 ENO1 NUP210 SMARCB1 RRS1 NAT10 PLIN3 NUP93 CALU DDX41	up	***
GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_DN	0.0000000	0.0000000	0.8753251	-0.4333291	-2.304002	175	SLC47A1 MNDA FBP1 PTPRE LIPA TRPV2 LMO2 CLEC10A STX11 ALAS1 NCF2 CD9 AGPAT4 FRAT1 SLC11A1 EPB41L3 ZEB2 CLCF1 MAN2B1 CD33 LMNA ITGA5 IFI30 GRN TLE4 SDCBP ACSL3 DAB2 PLBD1 CLIC4 ITGAX FCER1G GCA CLIP4 IL7R PI4K2A NCKAP1L NINJ1 RPS6KA2 PRCP VAMP3 C1QA RAB31 HK3 CTSZ IFNGR1 RHOQ SLC22A1 ATG3 SAV1 MILR1 FPR2 CD81 APLP2 LGALS3 GABARAPL1 CCR1 NPTN TSPO MOB3B PDLIM5 SLC31A1 CEP170 RTN1 MS4A4A ALDH2 SLC2A9 MEGF9 SCPEP1 SOAT1 DAPK1 GLUL CAMSAP2 THEMIS2 CREG1 EHD4 RNF13 LYZ	down	***
GSE27434_WT_VS_DNMT1_KO_TREG_DN	0.0000000	0.0000000	0.8753251	-0.4331834	-2.303917	184	SMAD6 CXCL3 IL1A CPEB2 IL1B EGR2 GTF2E2 IL1RL1 IL1RN MOB1B IER2 TRA2B SLC25A17 CSRP1 BTG2 EIF5 MAP3K8 PAG1 PPP3CA NR4A1 NFE2L2 NDEL1 SRGN BTG3 UBE2D3 ATP6V1H PDGFA RHOB IL10 LIN7C PLAUR STX3 SOCS2 PDE8A CDKN1A CXCL2 SELP DUSP1 INHBA DSTN PROCR SPIN1 ETF1 SGK1 SOCS3 KCTD12 JUNB DNAJA1 EPC1 AK1 PPP1R15A WTAP IFRD1 EEA1 CD83 DDX5 GMFG ATP13A3 FOS RHOQ PELI1 EHD1 TGIF1 CD86 PIM1 STK40 ETS2 IST1 ICAM1 TNFAIP8 SERTAD1 HSP90AA1 ARIH1 RBM18 HNRNPK NFKBIA PTEN MCOLN2 TNFSF9 ATF4 PPP1CB YTHDC1 EGR1 SERPINE1 CLEC4E ZFP36 EFNB2 SRSF11 UBE2N DLD IRF1	down	***
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP	0.0000000	0.0000000	0.8753251	-0.4332196	-2.303420	175	SIK1 CITED2 CRY2 ELF2 YPEL5 DYRK1A FRAT1 TMX4 CCNL1 TXNIP ANXA1 ATP2B1 SH2B3 UBL3 BTG2 KLF6 STOM JAM3 RGCC TMEM123 NDEL1 TMEM41B CLK1 TIPARP MOAP1 KIAA0513 COQ10B LEPROTL1 KLF11 MED6 KLF7 MGAT4A CLK4 PER1 DUSP1 CCDC59 ARL4A IL7R VCPKMT MYLIP KLRB1 SGK1 HECA PLK3 JUNB PTGER4 PIK3R1 MBNL2 GPR183 ENTPD4 UVRAG TSPYL1 FOS PELI1 KLF2 PTP4A1 YTHDF3 FOSB TSC22D1 IRS2 ZNF136 FCGRT TOB1 KANSL2 HAUS3 RLF CXCR4 EPHA4 NLRP3 CREBBP RASSF8 DNAJB9 RORA DAZAP2 NR3C2 NUP160 PPP1CB ARHGEF18	down	***
BERTUCCI_INVASIVE_CARCINOMA_DUCTAL_VS_LOBULAR_DN	0.0000196	0.0004939	0.5756103	-0.5741752	-2.297612	38	RBP4 TEK PECAM1 FABP4 EMCN CAV1 TGFBR2 TXNIP ERG SFRP1 TUBB6 CCDC82 VWF FOXN3 PDK4 ADCY2 MFAP4 CD34 NECAB1 MRGPRF SPARCL1	down	***
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_DN	0.0000000	0.0000000	1.0376962	-0.4135388	-2.296632	287	CXCL3 EREG CD52 FCN1 PHACTR1 PECAM1 OSBPL1A CD55 IL1B LTA4H FBP1 CYP27A1 SNX10 LPXN PID1 FYN LY86 LMO2 CCRL2 AQP9 MYD88 C5AR1 NEDD9 LAMP1 EPB41L3 TEX2 TMX4 CCNL1 DPEP2 PLA2G7 MCTP1 HBEGF SLC7A7 ASAH1 ENTPD1 ANXA5 KLF10 LAIR1 RGCC CRTAM CES1 TCF7L2 MCL1 FBXL5 CFD TLE4 CASP1 KLF9 DAB2 ZFAND5 STK17B DENND3 MYO15B ITPK1 CTSD CCL3 CTBS SELL TM6SF1 DNTTIP2 PINK1 ZNF706 HLA-DQA1 MAPRE2 NCOA1 HEXB SGK1 CD48 C1QA MITF SH3BP5 TREM1 TMEM251 ZNF804A PTGER2 ATP13A3 CXCL5 PPM1F RHOQ PELI1 ICAM2 NKG7 RIN2 EMC7 TIMP2 CHPT1 TFEB TSC22D1 GALC APLP2 SOD2 LGALS3 CCR1 DECR1 RGS2 ETS2 RNF138 IL18 CCDC69 SLC31A1 CALHM2 MS4A4A CDKN1C SIK3 NLRP3 TBC1D1 ICAM3 FDX1 BCAT1 NRG1 MT2A SFPQ MIS18BP1 GRPEL1 ARFGAP3 CACNA2D3 ACAT1 SPHK1 DMXL2 ATP6V0A1 HERPUD1 EGR1 BHLHE41 DUSP6 NR4A2 CX3CR1 CLEC4E AOAH ITGAL FPR1 ZFP36	down	***
GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000000	0.0000000	0.8513391	-0.4385941	-2.296416	166	PNPLA6 SWAP70 PECAM1 CD55 GPR65 PTPRE LRRFIP1 COQ2 GFOD1 BCL2A1 FUCA1 FRAT1 TGFBR2 TRIB1 FGR TACC1 ASAH1 SERINC1 MAP3K8 ANPEP SLC7A11 IL18R1 ATP6V1B2 ZMIZ1 PTPN12 EVI2B PTAFR THBS1 ERP44 PNRC1 CLK4 SMAD7 ADIPOR2 GNAQ CMTM6 SNN TMEM9B MCMBP AREG PSEN1 PGD CRNKL1 SEC14L1 HK3 PPP1R15A RNF24 RALB PPM1F ACSL1 FOS ATP6V0D1 RHOQ PELI1 TNFSF13 MBP CHIA TFEB EHD1 CTNNAL1 APLP2 GABARAPL1 CCNH SELPLG EPN2 MEGF9 OSER1 KIT PTEN CREG1 RABGEF1 KAT5 CHP1 AOAH RB1CC1 KBTBD11	down	***
ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN	0.0000003	0.0000115	0.6749629	0.6496284	2.295628	39	FOXM1 HELLS BUB1B CCNB1 CENPF MND1 DEPDC1 DEPDC1B AURKB CDC6 MYBL2 RANBP1 CHAF1A TOP2A AURKA CKS1B CDK1 POLE2 BIRC5 DNA2	up	***
RHEIN_ALL_GLUCOCORTICOID_THERAPY_UP	0.0000011	0.0000422	0.6435518	-0.5073091	-2.295621	66	SWAP70 CD55 MNDA GPR65 MIR22HG LY86 TXNIP ASAH1 MAP3K8 MS4A1 AHNAK KLF9 GRK5 LY96 PTPRC CA1 AREG CREM DDX17 IFNGR1 CSTA GLIPR1 GPR183 IDS RGS13 PELI1 CHPT1 DUSP5 GABARAPL1 RGS2 GPR18 IQSEC1 GLUL ZNF165 LYZ NR4A2 S100A8	down	***
GNF2_H2AFX	0.0000005	0.0000199	0.6594444	0.7025633	2.292552	29	FOXM1 CENPF KIF18B ASPM CDCA8 PTTG1 CCNB2 MCM2 TYMS PRC1 CCNF ZWINT AURKA RRM2 DNAJC9 NUSAP1 CDK1 BIRC5 DLGAP5 CDC20 CCNA2 SHCBP1 CENPE	up	***
GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN	0.0000000	0.0000000	0.8870750	-0.4293781	-2.292343	185	EPAS1 SLC31A2 HVCN1 LTA4H CAT MIR22HG ENG CD9 LILRB3 ACER3 SH2B3 B3GNT5 MCTP1 SLC7A7 ARSB RASGRP4 GNGT2 MAP3K8 RNF144B STOM IL18R1 ADAMTSL4 PTPN12 FABP5 CFD LIMS1 PIP5K1B FUT7 TMED5 DENND3 LY96 CDKN1A C9orf72 TM6SF1 ZMPSTE24 SLC6A6 TM9SF2 GNAI2 EMP3 VAMP3 RNF149 PGD SNAP23 CTSZ ATP6V0B CCDC50 GSTO1 GRB2 RAB8A REL AP3B1 RALB WDFY4 TNFSF13 DGKG AKIRIN2 PEA15 DUSP5 TGFB1I1 PDLIM1 GALC MEIS1 RGS2 NBN RTN1 CEBPD ACTB GLUL PDE4A LYST TMCC3 FEZ2 SLFN11 IRF2 CYBA HERPUD1 CHP1 CSF2RB SH3BGRL3	down	***
GO_POSITIVE_REGULATION_OF_COAGULATION	0.0000356	0.0008129	0.5573322	-0.6600765	-2.292269	23	THBD TBXA2R CD36 NFE2L2 THBS1 SELP HPSE TLR4 PLEK PSEN1 ENPP4	down	***
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN	0.0000000	0.0000000	0.8634154	-0.4309259	-2.291224	175	WEE1 CXCL3 CXCL16 SOWAHC IL1B CCRL2 BACH1 CITED2 FOSL1 IDI1 SLC15A3 NUDT9 BCL2A1 TRIB1 CLCF1 MAP3K8 PPP2R2A SRGN MCL1 LRP4 CSRNP1 LRRC57 MEFV LAPTM5 CDKN1A C9orf72 CCL4 IGFBP2 DUSP1 PLEK MAFF CMTM6 RASGEF1B LACC1 SRF NRROS NINJ1 AREG IL6 RYBP SOCS3 ETV3 JUN CUL4A FOXN2 PPP1R15A PTGER4 DHX15 ENPP4 IFRD1 DDX5 GRASP HNRNPD EHD1 TGIF1 TESK2 DUSP5 IRS2 PCDH17 TAGAP STK40 PDE4B ETS2 GEM ICAM1 SERTAD1 IER5 CXCR4 HNRNPK EPHA2 TRAF1 NFKBIA MRPL32 ANXA11 PURB PIM3 YTHDC1 JDP2 EGR1 CHP1	down	***
GO_DNA_HELICASE_ACTIVITY	0.0000001	0.0000069	0.6901325	0.5762280	2.290382	65	DDX11 DDX12P RUVBL1 CDC45 POLQ PIF1 GINS1 MCM4 MCM2 RAD54B MCM8 GINS4 RUVBL2 MCM7 HELB MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 RECQL5 NAV2 DNA2 RECQL4 CHTF18 GINS2 CHD5 RAD50 MCM6 CHTF8 MCM5 IGHMBP2 RTEL1 RFC5 RAD51 CHD3	up	***
HALLMARK_G2M_CHECKPOINT	0.0000000	0.0000000	0.8986712	0.5013057	2.290113	181	CDC45 TROAP NEK2 CENPF POLQ PBK NDC80 PRIM2 TTK CDK4 RACGAP1 TRAIP POLE STIL PLK1 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 E2F3 CCNB2 MCM2 CDC25A MYBL2 PRC1 EFNA5 CCNF LIG3 HMMR EXO1 SMARCC1 KIF23 CHAF1A MKI67 KIF15 BUB1 TOP2A AURKA ODF2 POLA2 KIF2C E2F2 RAD54L KIF11 MCM3 LMNB1 CHEK1 ORC6 MAD2L1 PML MNAT1 INCENP CKS1B CDKN2C NUSAP1 CDK1 UCK2 BIRC5 E2F1 EZH2 TNPO2 EGF CBX1 KPNB1 TACC3 KIF22 HIRA DTYMK GINS2 KIF20B SAP30 CDC7 CDC20 HMGA1 MCM6 MCM5 SNRPD1 SRSF1	up	***
GO_AXONEME_ASSEMBLY	0.0000002	0.0000088	0.6901325	0.6347154	2.289571	42	SPAG17 TTC26 DNAI1 RSPH1 ARMC4 SPAG16 HYDIN TEKT2 CCDC114 DNAH8 GAS8 DNAAF3 CCDC40 DRC1 LRGUK LRRC6 DNAH5 DNAH7 CCDC151 IQCG SPAG1 DNAJB13 TTLL3 DNAI2 RSPH4A DNAH1 ZMYND10 ARMC2 DNAAF1 WDR63	up	***
GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN	0.0000000	0.0000000	0.8870750	-0.4334980	-2.287217	171	PAN3-AS1 ZC3H12C RRN3P2 OTUD1 BACH1 YPEL5 NCF2 TET2 FRAT1 ABCB1 ZEB2 AVPI1 ATP2B1 UBL3 SERINC1 PICALM DACH1 AKT3 ZFYVE16 SRGN EPM2AIP1 TCF7L2 ZSWIM6 TCP11L2 PLAUR THBS1 SOCS5 LAPTM5 PDE3B NR1D2 C9orf72 PNRC1 CLK4 DUSP1 IL7R BTG1 CREBRF HCAR3 FRY HECA USO1 IFNGR1 CSTA CCR7 PNPLA8 GPR183 IDS OGFRL1 TSPYL1 PELI1 FOXO3 TGIF1 FAM228B BAZ2B HBP1 APLP2 KYNU N4BP2L2 RGS2 SLC43A2 CXCR4 EPHA4 SIK3 NLRP3 CREBBP METTL7A PAIP2 THEMIS2 ZBTB44 ARRDC2 DMXL2 ZNF106 ITGB1 RB1CC1 ZFYVE1 ZFP36 SLC26A11 PIAS2 TSC22D2 ATP8A1 CCPG1 RAB11FIP2 SIRT1 DUSP22	down	***
STK33_NOMO_UP	0.0000000	0.0000000	0.9865463	-0.4140711	-2.287215	261	EPAS1 CXCL3 ACP5 KMO IL1A HMOX1 SLC12A6 OLR1 IL1B FABP4 DCSTAMP MIR22HG THBD PID1 EGR2 OTUD1 AQP9 C5AR1 ZEB2 NCEH1 HECW2 CLEC7A BTG2 MAP3K8 KLF6 PTX3 CRK TFEC BTG3 RHOB IL10 CSRNP1 RAB12 PTPRO COQ10B DAB2 TNFSF15 STK17B LY96 RIT1 CADM1 NR1D2 NKIRAS1 CXCL2 CCL4 TM6SF1 DUSP1 CD300C IL7R MAFF LACC1 CREBRF HCAR3 CD80 RNF149 SGK1 RAB8B NECAP1 JUN ARL5B CPEB4 C20orf194 TREM1 JUNB OSTM1 MTMR9 PPP1R15A GLIPR1 KBTBD8 GPRIN3 FOS PELI1 RIN2 BTBD7 KIAA0232 TGIF1 CDC37L1 DUSP5 MEIS3P1 HBP1 PPP3R1 WBP2 KYNU HINT3 ANKRD12 STX12 RGS2 CLEC2B CCL20 ICAM1 CTTNBP2NL CGRRF1 HAVCR2 ULK2 DAPK1 STAM2 TBCEL SIGLEC9	down	***
chr12q14	0.0000004	0.0000178	0.6749629	0.6385243	2.287076	41	HMGA2 GRIP1 GAPDHP44 PPM1H LRIG3 KLF17P1 AVIL TSFM C12orf66 METTL1 CDK4 CYP27B1 CAND1 XPOT HELB CTDSP2 TSPAN31	up	***
GSE18893_TCONV_VS_TREG_2H_TNF_STIM_DN	0.0000000	0.0000000	0.8634154	-0.4293529	-2.283088	176	MS4A7 GIMAP8 MIR22HG PTPRE RRN3P2 BACH1 YPEL5 TET2 ZEB2 ATP2B1 UBL3 LATS2 SERINC1 MS4A1 C1orf162 ZFYVE16 TCF7L2 PTPN12 TCP11L2 RNFT1 PLEKHM3 ZFAND5 THBS1 SCAF4 SSH1 MGAT4A C9orf72 PNRC1 LBH CLK4 PLEK PPP2R5C CUL5 EFR3A BTG1 CREBRF FRY NXF1 HECA ETV3 DDX17 TREM1 RABGAP1 CSTA FBXO11 PNPLA8 FAM43A CD7 OGFRL1 RNF146 BTBD7 BAZ2B ZNF844 MAP3K2 HBP1 APLP2 ADPGK PHF11 ANKRD12 ATAD2B IST1 CDC42EP3 CXCR4 TRAPPC8 EPHA4 NLRP3 DDX59 CREBBP STK4 FNIP2 TMCC3 THEMIS2 DAZAP2 SLC35A1 ZBTB44 ARRDC2 CBX7	down	***
MARSON_BOUND_BY_E2F4_UNSTIMULATED	0.0000000	0.0000000	1.3110148	0.4585531	2.283023	537	DDX11 CEP72 SPICE1 HELLS KIF20A MDM1 HJURP CDC45 PARPBP MCM10 FANCI CHEK2 BUB1B NUP107 NEK2 CCDC34 DROSHA POLQ C21orf58 MND1 PBK KIF18B NDC80 PRIM2 DEPDC1 PIF1 DEPDC1B CDCA7 TTK CDCA2 AGFG2 RACGAP1 GTSE1 ANLN TRAIP ASPM NABP2 STIL FLAD1 DGCR8 PLK1 NUF2 IFT27 CDCA8 AURKB CENPA ECT2 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 CDC25A MYBL2 PMS2 PRC1 XRCC2 ORC1 CCNF DTL C19orf57 MCM8 MIS18A NCAPD2 CDT1 SPDL1 LSM5 CXCL10 CCDC150 MELK HMMR EXO1 KIF23 CEP55 RND2 HLTF KIF15 AP4M1 BUB1 FANCA TOP2A AURKA EME1 CBX3 SAE1 POLD2 KIF2C POC1A CLSPN RRM2 CDCA5 PRKDC CDNF RAD54L MRPL27 KIF11 PASK MCM3 CDC25C AIMP2 SARS2 ABCB6 TOPBP1 CHEK1 DNAJC9 ORC6 CC2D1A CKAP2L NFYA RAD51AP1 TIMM50 TRMT2A SPC24 DSCC1 BRIP1 BLM PML SKP2 INCENP POLN KNSTRN EFCAB11 NUSAP1 ASF1B CDK1 POLE2 EXOSC2 CENPH BIRC5 CCM2 C1orf112 NUDT2 TYW1 E2F1 UNG CMTR1 NEIL3 FEN1 EZH2 SPAG5 MRPS12 OARD1 TTI1 MTBP CBX1 DIAPH3 RECQL4 MAST1 CENPP C9orf43 KPNB1 RANGAP1 NET1 DNMT1 PARS2 FANCG PELP1 INTS7 DLGAP5 TACC3 MNS1 KIF22 CHTF18 STOML1 ESCO2 ANP32E C15orf41 NUP85 MAGOHB CEP128 RAB24 CDC7 CENPK SASS6 GEMIN6 BRD8 CDC20 RPRD1B PALB2 CENPM YLPM1 AAAS UBXN6 RPUSD1 FANCM CDK5RAP2 MCM6 XRCC4 MCM5 CD2BP2 TDP1 HAUS6 C5orf22 TFAP4 SRSF1 C1orf109 GINS3 STMN3 KATNB1 AP4B1 STK35 TCERG1 ALG8 LRRC14 ALMS1 MSH2 CCNA2 PRIM1 DZIP3 PRR11 RTEL1 SHCBP1 PAK4 ABHD10 RAD51 TRIP4 ZWILCH ARHGAP11A KIAA0825 NME7 WDR76 MXD3 SMC2 TONSL XPC CENPE TCF3 C1orf159 SMPD4 TP53 PAICS UBE2C NCAPD3 RAD1 RRS1 ZNF367 TTLL5 KIF24 CALU SART3 BRIX1 C12orf10 SETD5 NCAPH ALKBH2 LMBRD2 TFB1M CSTF1	up	***
REN_BOUND_BY_E2F	0.0000004	0.0000159	0.6749629	0.6023038	2.282076	52	NDC80 PRIM2 TTK CENPA PTTG1 CDC6 E2F3 CDC25A UMPS ORC1 HLTF TOP2A POLA2 E2F2 PRKDC RAD54L MCM3 CHEK1 MAD2L1 CBX5 CDK1 UNG FEN1 TK1 POLD1 MCM6 MCM5 MSH2 CCNA2 RAD51 SMC2 CENPE TP53	up	***
GO_DNA_DEPENDENT_ATPASE_ACTIVITY	0.0000000	0.0000001	0.7881868	0.5392533	2.280525	97	DDX11 DDX12P RUVBL1 CDC45 POLQ TTF2 PIF1 GINS1 MCM4 MCM2 RAD54B XRCC2 MCM8 GINS4 RUVBL2 HLTF TOP2A SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 MNAT1 RECQL5 NAV2 DNA2 RECQL4 RAD51D CHTF18 GINS2 CHD5 RAD50 MCM6 CHTF8 MCM5 ZRANB3 IGHMBP2 MSH4 MSH2 SMARCA4 RTEL1 RFC5 RAD51 CHD3	up	***
FISCHER_DREAM_TARGETS	0.0000000	0.0000000	1.5631820	0.4474023	2.277272	841	TRIP13 DDX11 FOXM1 CEP72 HELLS KIF20A MDM1 HJURP CDC45 TICRR PARPBP MCM10 FANCI ZNF273 TROAP CHEK2 BUB1B NUP107 NEK2 CCNB1 CCDC34 CENPF TIMELESS POLQ UBE2T GGCT MND1 PBK KIF18B TTF2 NDC80 PRIM2 DEPDC1 PIF1 TBRG4 BRCA1 THEM4 DEPDC1B CDCA7 ZNF138 TTK GINS1 CDCA2 CDK4 RACGAP1 IQGAP3 E2F8 GTSE1 DBF4B KIF14 ANLN CCDC14 TRAIP DNMT3B POLE ASPM STIL DGCR8 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 FIGNL1 ZNF714 UHRF1 KNOP1 MCM4 SPATS2 MCM2 RAD54B CDC25A MYBL2 PRC1 XRCC2 ORC1 CCNF EIF3B DTL MCM8 MIS18A GINS4 CAND1 SHMT2 NCAPD2 ZWINT CDT1 ZNF107 SPDL1 TRIM45 LSM5 HAUS5 RANBP1 WDR62 C5orf34 TTLL4 CASP2 CCDC150 MELK HMMR EXO1 NUDT1 C19orf48 SMARCC1 KIF23 CEP55 CHAF1A RPL39L MKI67 HLTF KIF15 KNTC1 RHNO1 PAFAH1B3 BUB1 FANCA CCDC77 AUNIP TOP2A EXOC4 CCT5 CENPL AURKA EME1 NUP155 CBX3 ODF2 POLA2 SAE1 POLD2 GTPBP3 KIF2C MCM7 E2F2 CENPW POC1A CLSPN RSRC1 MPHOSPH9 RRM2 MMS22L CDCA5 PRKDC WDHD1 RAD54L MRPL3 KLHDC4 ZNF146 KIF11 PASK FANCD2 GPSM2 MCM3 LMNB1 CDC25C EMG1 ZNF530 TOPBP1 CHEK1 DNAJC9 ORC6 ACTL6A MAD2L1 CKAP2L CENPO RAD51AP1 XRCC1 KHK SPC24 DSCC1 PKMYT1 BRIP1 CAD RAD18 BLM LRRC45 ZNF587 SKP2 PSRC1 CKLF INCENP KNSTRN CKS1B NCAPG2 CDKN2C NUSAP1 CBX5 ASF1B IQCB1 ZNF45 CDK1 HDGF RNPC3 POLE2 CEP97 EXOSC2 CENPJ RFWD3 CENPH BIRC5 C1orf112 GMNN POC5 POLR3K E2F1 UNG NCAPG DNA2 MRPL17 TCTN2 KIF2A NEIL3 FEN1 EZH2 NUP205 SPAG5 TNPO2 SAPCD2 OARD1 SF3B3 TTI1 NAPEPLD MTBP ATAD3A DIAPH3 RECQL4 CENPP RNASEH2A KPNB1 RANGAP1 CHCHD3 NRGN NET1 SNRNP25 MYO19 DNMT1 FANCG INTS7 CCNE1 CEP192 TUBG1 DCLRE1C DLGAP5 ARHGAP11B FOXRED1 TACC3 SNRPA MNS1 RAD9A LONP1 KIF22 TRIM37 SSRP1 FBXO4 TK1 DTYMK CHTF18 CENPQ ESCO2 GINS2 FZR1 ANP32E PKP4 AGPAT5 TCEA1 KIF20B SAP30 ANAPC1 BCL2L12 POLD1 NUP85 MAGOHB ATAD5 CDC7 NIF3L1 DHTKD1 CENPK SASS6 SUPT16H FN3KRP PFAS CKAP5 L3MBTL2 KLHL23 BRD8 CDC20 PALB2 CENPM AAAS EFHC1 C12orf65 FAF1 RRP9 GPATCH4 POP7 CDR2 FANCM CDK5RAP2 MCM6 METTL2B CKAP2 XRCC4 MCM5 ANKRA2 HEATR1 TDP1 ZRANB3 SNRPD1 HAUS6 FAM161A TFAP4 SRSF1 GINS3 DOLPP1 EXOSC5 RCC1 HAUS4 SLC1A5 LSM4 MARCKS WDYHV1 ATAD2 CEP152 TCERG1 NUP62 CEP85 SUV39H2 ALMS1 MSH2 CCNA2 PRIM1 DZIP3 PRR11 DCPS GTF3C2 SHCBP1 RFC5 GTPBP2 USP39 WDR4 ABHD10	up	***
RPS14_DN.V1_UP	0.0000000	0.0000000	0.8390889	-0.4373064	-2.275595	159	SLC31A2 KMO IL1B MNDA LPXN PTPRE PID1 LY86 ST3GAL6 RASAL2 FLVCR2 BCL2A1 NCF2 CD9 FUCA1 IGSF6 PILRA PLA2G7 ADA CLEC7A ANPEP SIRPA CRTAM TFEC PDE4D PDGFA RHOB EVI2B PTPRO CASP1 BST1 STX3 MPL LY96 CDKN1A ITGAX TM6SF1 EVI2A SH2D2A ANXA3 CRIM1 VWF HCK FRY HESX1 CTSS SH3BP5 RAB31 KCTD12 TYROBP CSTA PTGER4 GPR183 TNFRSF9 NKG7 RIN2 CR1	down	***
RHODES_UNDIFFERENTIATED_CANCER	0.0000002	0.0000078	0.6901325	0.5814184	2.275480	60	TRIP13 FOXM1 CCNB1 KIF14 CENPA CDC6 MCM2 MYBL2 CCT6A NCAPD2 NME1 MELK NUDT1 KIF23 TOP2A KIF2C GPSM2 MCM3 MAD2L1 CXCL9 CKS1B CDK1 SSBP1 BIRC5 EZH2 ILF2 COL1A2 DLGAP5 PSMD2 CDC20 MCM6	up	***
GO_CATALYTIC_ACTIVITY_ACTING_ON_DNA	0.0000000	0.0000000	0.8986712	0.4976925	2.274259	182	HMGA2 DDX11 DDX12P RUVBL1 CDC45 POLQ PIF1 GINS1 DNMT3B POLE RBBP8 MCM4 MCM2 RAD54B MCM8 LIG3 GINS4 SMUG1 NME1 TOP3B RUVBL2 EXO1 POLM TOP2A EME1 POLA2 POLD2 SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 LIG1 EME2 XRCC1 THAP10 DSCC1 BRIP1 BLM ERCC2 RECQL5 POLN TERC POLE2 NAV2 UNG DNA2 NEIL3 FEN1 RECQL4 TEP1 DNMT1 DCLRE1C POLL MBD4 RAD9A CHTF18 MGMT GINS2 CHD5 POLD1 POLB SLX4 DNASE1 RAD50 PGBD5 HMGA1 ALKBH4 MCM6 MGME1 DNMT3A CHTF8 MCM5 TDP1 ZRANB3 IGHMBP2 RTEL1 RFC5 RAD51 N6AMT1 CHD3 MPG NEIL1 APEX1 RAD1 ERCC3 ALKBH2 MUS81 DNASE1L2 TOP3A METTL4 DFFB RAG1 CHD8 DCLRE1B DQX1 DCLRE1A ASCC3 XRCC5	up	***
GO_MACROPHAGE_ACTIVATION	0.0000002	0.0000078	0.6901325	-0.4881929	-2.274088	78	PLA2G10 C5AR1 IL1RL1 SLC11A1 FOXP1 CD93 GRN SLC7A2 IL10 THBS1 CEBPA CCL3 PTPRC TLR4 IL6 C1QA JUN TYROBP IFNGR1 PRKCE SUCNR1 CST7 TREX1 CD74 JMJD6 FPR2 SYT11 HAVCR2 CTSC RORA LDLR SPHK1 CSF2 TREM2 WNT5A SHPK	down	***
EPPERT_HSC_R	0.0000000	0.0000015	0.7337620	-0.4584022	-2.273990	105	PAN3-AS1 FGD5 INSIG1 ST3GAL6 ABCB1 ERG ZBTB4 RBM7 MCTP1 EIF5 RNF125 DACH1 RGCC SPTBN1 ZEB1 ITSN2 TMEM38B FOXO1 KLF4 DRAM1 SOCS2 NPR3 HOPX ELK3 HES1 CRIM1 C2orf69 JUN EPC1 DDX5 KBTBD8 MSMO1 PLSCR4 TMEM107 MEIS1 RIMKLB TFPI TPT1 ZDHHC21 OSER1 DAPK1 MAFK DNAJB9 ZNF165 RPS20P22 FNBP1 DUSP6 PRKCH CD109	down	***
SONG_TARGETS_OF_IE86_CMV_PROTEIN	0.0000003	0.0000123	0.6749629	0.6030754	2.272505	51	FOXM1 FLAD1 PTTG1 TPX2 MCM2 TYMS UMPS MYBL2 ZWINT CDT1 MCM7 KIF11 MCM3 TOPBP1 DNAJC9 MAD2L1 BLM TMEM106C CDK1 E2F1 UNG EZH2 CCNE1 TK1 RPA1 MCM6 MCM5 DDX23	up	***
GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN	0.0000000	0.0000000	0.8513391	-0.4291470	-2.271272	169	PPARG SOWAHC DCSTAMP MIR22HG PTPRE LPL GFOD1 ST3GAL6 CORO1C NEDD4L FOSL1 GPCPD1 TBC1D7 TBC1D2 ZBTB2 MOB1B TRIB1 CNST RRAGC ZBTB21 SPRY2 CRTAM TXN ATP6V1H TMEM38B ATP6V1B2 RHOB FBXL5 NRARP MOAP1 ACSL3 ANKRD10 DAB2 TNFSF15 STX3 ATP6V1D ITGAX ATF3 LBH ZBTB43 FKBP15 MMP19 NRROS SERTAD2 BCAR3 SGK1 SH3BP5 TMEM251 SIGLEC15 SNX9 SLC3A2 RNASEK AKIRIN2 TSC22D1 COL15A1 BRI3 CCR1 CRY1 GNA13 GEM RLF CDC42EP3 TEX10 HAVCR2 MAFK EDN1 FNIP2 RABGEF1 GPALPP1 SERPINE1 NR4A2 SLC19A2 LHFPL2 HES4 RB1CC1	down	***
GSE14415_INDUCED_VS_NATURAL_TREG_DN	0.0000000	0.0000000	0.8634154	0.5046353	2.270949	162	TRIP13 CDC45 BUB1B CENPF IGF2BP3 MPP6 PBK BRCA1 DEPDC1B CDCA7 TTK GINS1 E2F8 KIF14 NOL12 ASPM PLK1 NUF2 CDCA8 CENPA ECT2 TPX2 CCNB2 MCM2 NME1 MELK HMMR EXO1 NUDT1 KIF23 CEP55 MKI67 KIF15 BUB1 TOP2A SAE1 KIF2C MPO CLSPN WDHD1 RAD54L KIF11 GPR146 MCM3 LMNB1 CDC25C CKAP2L DCTPP1 SPC24 ALDOA INCENP CKS1B NCAPG2 ASF1B ANAPC5 CDK1 CENPH BIRC5 ADAP1 NCAPG NEIL3 EZH2 DLGAP5 TACC3 AARSD1 KIF22 ARL6IP4	up	***
GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN	0.0000000	0.0000000	0.8390889	-0.4270824	-2.267316	174	PPARG SOWAHC DCSTAMP PTPRE LPL EGR2 GFOD1 ST3GAL6 CORO1C GPCPD1 TBC1D7 ZCCHC2 TBC1D2 MOB1B TRIB1 RRAGC LINC01010 SPRY2 CRTAM ATP6V1H TMEM38B ATP6V1B2 RHOB FBXL5 MOAP1 ACSL3 ANKRD10 DAB2 TNFSF15 STX3 ATP6V1D ITGAX ATF3 ATP6V0D2 LBH ZBTB43 PPP2R5A UBASH3B FKBP15 HTRA4 EFR3A PI4K2A RASGEF1B MMP19 CLN8 NRROS SERTAD2 BCAR3 SGK1 PHACTR2 SH3BP5 TMEM251 EEA1 SIGLEC15 SNX9 SLC3A2 AKIRIN2 COL15A1 LGALS3 BRI3 CCR1 CRY1 GNA13 GEM RLF CDC42EP3 TEX10 HAVCR2 AMZ2P1 MAFK EDN1 FNIP2 MT2A RABGEF1 SERPINE1 NR4A2 LHFPL2 HES4 MT1E PPFIA1 TRPM7	down	***
PATIL_LIVER_CANCER	0.0000000	0.0000000	1.3422338	0.4534307	2.265765	576	TSPAN8 DKK1 TRIP13 ONECUT2 ONECUT1 DDX11 FOXM1 HELLS DDX12P HJURP CPLX2 CDC45 TROAP NEK2 BAIAP2L2 CENPF IGF2BP3 FLVCR1 UBE2T PSPH PBK CLGN PRIM2 DEPDC1B CDCA7 LCN2 CDK4 CCDC14 TRAIP SPP1 MSTO1 COL7A1 FLAD1 AP1S1 BAIAP2L1 PLK1 NUF2 CDCA8 PTTG1 ALDH18A1 ESPL1 CDC6 TPX2 E2F3 MCM4 SPATS2 PRKCA TYMS CDC25A MYBL2 AACS DTL GON4L XPO5 LIG3 MIS18A XPOT ZWINT CLPTM1L ITGA2 OSBP2 CASP2 HMMR NUDT1 KIF23 CEP55 CHAF1A CUL7 HLTF RNF216P1 TP53BP1 KNTC1 RHNO1 PAFAH1B3 BUB1 TOP2A CCT5 AURKA NUP155 HHAT YKT6 TPR E2F2 CENPW MPHOSPH9 CPD RRM2 CDCA5 PRKDC RHOBTB3 RNF43 KIF11 GPSM2 MCM3 PLTP HORMAD1 CD24 SLC9A3R1 CHEK1 MAD2L1 NFYA ZKSCAN1 PKMYT1 PTGFRN FADS2 TTYH3 ALDOA DLG5 SKP2 CKLF KNSTRN ZNF512B CKS1B NCAPG2 CDKN2C HPS4 FASTK NUSAP1 TMEM106C ASF1B PAK1 CDK1 ARHGAP39 CEP97 CENPJ DIDO1 UCK2 ZNF652 GMNN RBCK1 E2F1 PRPF6 LARP1 PEG10 FEN1 CPNE1 EZH2 NUP205 TAF6 LRRC42 PLCG1 SNRPE CBX1 VPS72 RECQL4 LAPTM4B UBN2 LGR5 FANCG GRAMD1A INTS7 ILF2 CEP192 POFUT1 RHOC TRIM24 TUBG1 COL1A2 GNPAT DLGAP5 SMG5 SNX27 SLC26A2 LMNB2 DVL3 TRIO PTGES2 COL5A2 DUSP12 RBM12B TMEM237 UBE2Q1 PPOX TK1 ENAH CENPQ RHBDD3 SCN8A JMJD4 ESCO2 LMTK2 TCEA1 XPR1 KIF20B C15orf41 TSEN54 POLD1 C12orf73 ENPP2 CABLES2 LSM14B ETV4 RNF187 SUPT16H KDELR3 KLHL23 CDC20 CENPM KIAA0100 TUBG2 ZCCHC17 HMGA1 AP3M2 FAM136A ACLY MCM6 MYPOP DNMT3A MYO5C THOC5 ANKIB1 MCM5 USP21 MALSU1 PYGO2 DUS4L CREB3L2 LSM4 SH3PXD2B TMEM45B STK35 ATAD2 INTS8 CEP85 RER1 ATP6AP1 MCRS1 CCNA2 BBX CAP2 RNF157 LPGAT1 ZWILCH RDH10 TYSND1 TARBP1 SOX12 RPRD2 F13A1 PTPRF UBAP2L ARHGEF39 GNA12 RNF213 ADAM15 KIAA1522 KDM5B HGS SLC36A1 CDC25B UBE2C CYSTM1 LINC00205 FBXO45 BCAT2 TMEM98 BTN2A1 RAD1 SLC39A1	up	***
MANALO_HYPOXIA_DN	0.0000000	0.0000000	1.0073180	0.4803210	2.265605	263	TRIP13 DDX11 HJURP RUVBL1 PARPBP MCM10 FANCI ELOVL6 PAIP1 PBK TSFM BRCA1 MRPL46 GINS1 NOL12 STIL CDC6 TPX2 MCM4 MCM2 UMPS FERMT1 PRC1 CCNF ZWINT SPDL1 NME1 RANBP1 TTLL4 MELK EXO1 CISD1 NLE1 KIF23 CHAF1A RPL39L EEF1E1 POLA2 POLD2 MPHOSPH9 RRM2 RBM28 AKAP1 MCM3 AIMP2 EMG1 DNAJC9 ORC6 MAD2L1 RAD51AP1 PKMYT1 CAD GNPDA1 PHB RGS4 SLC25A10 SKP2 PARP1 NUSAP1 ASF1B CDK1 POLE2 EXOSC2 C1orf112 ATIC GMNN POLR3K DNA2 FEN1 NUP205 MRPS12 PA2G4 FAM86C1 FANCG TELO2 CCNE1 TUBG1 SCLY PUS1 LMNB2 MNS1 POMT2 GINS2 PRMT7 NUP85 CDC7 NIF3L1 GEMIN6 PFAS DGCR11 HMGA1 RRP9 POP7 FAM136A SRRT MCM6 METTL2B UTP20 MCM5 HEATR1 SNRPD1 DDX23 NEK4 GINS3 URB1 SLC1A5 TSR1 PRMT5 CCNA2 SHCBP1 RFC5 AMDHD2 TUBGCP4 USP39 ABCF2 WDR4 WDR77 RAD51 ZWILCH RSAD1	up	***
MORI_LARGE_PRE_BII_LYMPHOCYTE_UP	0.0000001	0.0000039	0.7049757	0.5524560	2.264041	78	HJURP CCNB1 NDC80 CDCA7 TTK RACGAP1 E2F8 CENPA CCNB2 MCM2 MYBL2 PRC1 DTL MELK SMARCC1 KIF23 MKI67 TOP2A CENPL AURKA MCM7 RRM2 CDCA5 MCM3 LMNB1 LIG1 CKS1B CDKN2C ASF1B ANAPC5 CDK1 CBX1 RANGAP1 KIF22 ANP32E CDC20 HMGA1 MCM6	up	***
STK33_UP	0.0000000	0.0000000	0.9759947	-0.4114223	-2.262381	256	CXCL3 NLRC4 KMO IL1A HMOX1 SLC12A6 CD101 OLR1 CPEB2 IL1B FABP4 GPR65 MIR22HG THBD PID1 EGR2 OTUD1 AQP9 C5AR1 BCL2A1 NCF2 CD9 TRIB1 ZEB2 CD36 ANXA1 NCEH1 HBEGF HECW2 BTG2 KLF6 SLC7A11 CRK TFEC BTG3 RHOB CYBRD1 CSRNP1 RAB12 PTPRO MPEG1 COQ10B TNFSF15 LY96 RIT1 CDKN1A NKIRAS1 CXCL2 CCL4 DUSP1 MAFF CREBRF RNF149 SGK1 RNF141 NECAP1 JUN ARL5B CPEB4 C20orf194 TYROBP TREM1 JUNB OSTM1 MTMR9 DUSP8 PPP1R15A GLIPR1 KBTBD8 FAM177A1 GPRIN3 FOS PELI1 RIN2 BTBD7 MILR1 TGIF1 CDC37L1 DUSP5 MEIS3P1 ATXN1 HBP1 PPP3R1 WBP2 KYNU HINT3 ANKRD12 STX12 NBEAL1 RGS2 CLEC2B ICAM1 TRAC TFPI RTN1 TTLL7 HAVCR2 DAPK1 STAM2 TLR10	down	***
GO_CARDIOBLAST_DIFFERENTIATION	0.0000946	0.0018411	0.5384341	-0.7414115	-2.261650	15	TBX2 WNT3A REST TBX5 TGFB2 SRF RBPJ NOTCH1 MYOCD GATA6 NRG1 GREM1	down	**
MORI_IMMATURE_B_LYMPHOCYTE_DN	0.0000000	0.0000018	0.7195128	0.5479749	2.261260	81	HJURP CDC45 MCM10 NEK2 CCNB1 NDC80 CDCA7 TTK IQGAP3 E2F8 CENPA CCNB2 MCM2 PRC1 DTL MELK MKI67 TOP2A CENPL MCM7 RRM2 CDCA5 RAD54L MCM3 LMNB1 LIG1 CHEK1 CKS1B CDKN2C NUSAP1 CDK1 UCK2 EZH2 CBX1 DNMT1 DLGAP5 ANP32E CKAP5 CDC20 MCM6 CCNA2 SMARCA4 PRIM1 RAD51	up	***
FISCHER_G2_M_CELL_CYCLE	0.0000000	0.0000000	0.9545416	0.4864088	2.258868	210	HMGA2 TRIP13 FOXM1 KIF20A HJURP TROAP CHEK2 BUB1B NEK2 CCNB1 CENPF PLEKHA5 POLQ PBK KIF18B TTF2 NDC80 DEPDC1 PIF1 DEPDC1B SIX4 TTK CDCA2 RACGAP1 IQGAP3 GTSE1 DBF4B KIF14 ANLN ASPM STIL CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 TPX2 CCNB2 PRC1 CCNF MELK HMMR KIF23 CEP55 MKI67 KIF15 BUB1 TOP2A CENPL AURKA VANGL1 KIF2C MPHOSPH9 KIF11 GPSM2 CDC25C MAD2L1 CKAP2L ZNF587 PSRC1 KNSTRN CKS1B CDKN2C NUSAP1 CDK1 TNFRSF21 BIRC5 NEIL3 SPAG5 TNPO2 SAPCD2 NET1 DCLRE1C ARHGAP11B TACC3 KIF22 FZR1 ANP32E KIF20B SPA17 SAP30 NIF3L1 CKAP5 BRD8 CDC20	up	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_UP	0.0000000	0.0000000	0.8390889	-0.4310974	-2.257165	166	SC5D DENND5A SECISBP2L MIR22HG ST6GALNAC3 CITED2 BMPR2 PLEKHA1 INPP5A YPEL5 GNPTAB PDCL HEG1 TXNIP ZBTB4 DPEP2 FBXO7 PTPRM ASAH1 SPTBN1 SOX7 PPP3CC FBXL5 EVI2B ITPRIP SGTB PSTK MGAT4A CTBS C9orf72 DUSP1 IL7R UBASH3B PIK3R5 C16orf54 MYLIP SGK1 MAML2 AQP3 SNX29 MAP4K4 JUNB ATXN1L PNPLA8 KLF2 YPEL2 XYLT1 BIN2 NAP1L5 FAM204A VAV3 ABHD13 TSC22D1 IRS2 KCNA3 GABARAPL1 HELZ GPX3 ABL2 CGRRF1 EPHA4 TTC32 OSER1 TTC28 DNAJB9 ZFAND2A LYZ TNFSF8 NR4A2 FAM8A1 ASH1L-AS1 SPTY2D1 ATP8A1 MEF2D ITGA6 BBIP1 CEP68 PTGS2 YOD1 CD4 NFKBIZ MYO1F	down	***
GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN	0.0000000	0.0000000	0.8634154	0.5015682	2.256573	164	ALDH3B2 TRIP13 HELLS KIF20A HJURP CPLX2 CDC45 FANCI TROAP BUB1B NEK2 CCNB1 CENPF FAM153A PHGDH GINS1 RACGAP1 E2F8 IFT122 KIF14 POLE ASPM PTTG1 ESPL1 CCNB2 TYMS PRC1 DTL ZWINT HAUS5 MELK HMMR EXO1 MUC6 STRA6 CEP55 CHAF1A PAQR4 MKI67 TOP2A AURKA POLA2 RRM2 PRKDC RAD54L KIF11 GPSM2 DNAJC9 RAD51AP1 REPIN1 NCAPG2 NUSAP1 CDK1 TNFRSF21 GMNN NCAPG EZH2 SPAG5 DNMT1 CDK3 TUBG1 DLGAP5	up	***
GAVIN_FOXP3_TARGETS_CLUSTER_P6	0.0000000	0.0000026	0.7195128	0.5483396	2.255606	80	KIF20A MCM10 FBXW8 BUB1B NEK2 CCNB1 CENPF IGF2BP3 PBK ASPM PLK1 NUF2 CDCA8 AURKB TPX2 CCNB2 FIGNL1 TYMS HMMR CEP55 BUB1 AURKA KIF2C CLSPN RRM2 MMS22L CDCA5 RAD54L SERPINA3 SPC24 CKS1B NCAPG2 NUSAP1 CDK1 BIRC5 NCAPG SPAG5 ABHD4	up	***
GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_DN	0.0000000	0.0000000	0.8513391	-0.4245004	-2.254907	179	ACP5 KMO SLC47A1 MNDA DCSTAMP PTPRE LIPA LPL CCDC88A CRY2 SLC15A3 P2RY13 MEF2A MARCO MANBA CD9 TEX2 KIAA0355 PLA2G7 ASAH1 GM2A RNASE1 HLX SIRPA ZFYVE16 KDSR ARRB1 CCL22 PLAUR PLBD1 LY96 CDKN1A DCHS1 MAFF HEXB HCK KANK1 CTSS CYB5R1 C1QA KCTD12 CTSZ TYROBP IFNGR1 CSTA SNX2 IRF8 TNFRSF10B ACSL1 FOS RHOQ TIMP2 TCF4 TSC22D1 GOLGA8H LGALS3 FCGRT KYNU PLA2G15 IL18 RTN1 CXCR4 LRP12 NLRP3 ALDH2 SCPEP1 CTSC MMD CREG1 LPAR6 FEZ2 LYZ SERPINE1 CTSH LHFPL2 FTL ATP1B1 FPR3 UBE2W WNT5A	down	***
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP	0.0000000	0.0000000	0.8390889	-0.4295975	-2.254652	167	SC5D SGK3 RBMS2 GPR65 RAPGEF2 PTPRE IBA57 DDX6 CRY2 IDI1 YPEL5 ZBTB2 ABCB1 ATP2B1 CLCF1 DNAJC3 LTBP4 UBL3 CACNA2D2 ITGA5 LUZP1 RNF125 NFE2L2 TCF7L2 ITPRIP LINC00528 ARNTL NR1D2 PER1 DNTTIP2 SMAD7 ELMSAN1 IL7R TP53BP2 IKZF5 CNOT6L TOPORS DCTN6 ETV3 PLK3 IFNGR1 EPC1 PIK3R1 HSPA13 HERC1 RC3H1 ENTPD4 REL FAM177A1 ACSL1 AGFG1 PTP4A1 FOXO3 FOSB TGFB1 ZRANB1 ZBTB11 MIA3 MAP3K2 PDE4B SERTAD1 EPHA4 PSME4 RNF38 C1orf115 LYZ RABGEF1 RB1CC1 ZFP36 TBC1D23 FAM53B PIAS2 CCDC93 TSC22D2 CHKA SETD2	down	***
GO_ENDOCYTIC_VESICLE_LUMEN	0.0000008	0.0000320	0.6594444	0.7872467	2.253940	17	SAA1 LTF HP HBA1 HBA2 HBB MPO	up	***
FINETTI_BREAST_CANCER_KINOME_RED	0.0000007	0.0000287	0.6594444	0.8039540	2.249806	16	BUB1B NEK2 PBK TTK PLK1 AURKB SRPK1 MELK BUB1 AURKA CHEK1 CDK1	up	***
GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_DN	0.0000000	0.0000000	0.8513391	-0.4249888	-2.249264	169	FCN1 CD101 PHACTR1 LTA4H THBD HSD17B11 INPP5K SRSF7 YPEL5 FRAT1 IER2 TOE1 ANXA1 CHMP1B NR4A1 CD37 CPED1 EVI2B SNAI1 TLE4 MEFV BST1 KLF4 CDK9 MYO15B TLR4 DUSP1 RSL24D1 MAPRE2 RPL17 MYLIP ELF1 OASL SRSF3 SFTPB JUNB PIK3R1 GPR183 TAGLN2 SNRK FOS KLF2 PTP4A1 ICAM2 SRSF6 FOSB FAM204A RPL21 APLP2 JUND EIF3F LDLRAD4 NEK1 CEBPD CXCR4 RPS13 S100A4 ICAM3 P2RX1 C5AR2 CRTAP NR4A2 CX3CR1 EIF3L ZFP36 CD69 FXYD5	down	***
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_DN	0.0000000	0.0000000	0.8390889	0.5083845	2.248772	140	TRIP13 FOXM1 KIF20A HJURP TROAP NEK2 CCNB1 CENPF ZFHX4 PBK KIF18B DEPDC1 GINS1 ANLN ASPM PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 TBX19 TPX2 CCNB2 PRC1 SLC7A9 DTL KIF27 MYL6B DNAH14 CLDN1 MELK HMMR CEP55 MKI67 TSGA10 MAP10 AURKA METTL7B MYO10 C1orf226 RRM2 CDCA5 MGLL PLOD2 CDK1 BIRC5 PSAT1 ZNF789 SPAG5 DIAPH3 ITGA2B BBS5 TUBG1 DLGAP5 ZMAT5 RGS22 ZNRF2P1 C9orf152 TK1 ESCO2	up	***
chr4q21	0.0000025	0.0000837	0.6272567	-0.5074576	-2.248111	60	MRPS18C PRKG2 NUP54 COQ2 THAP9-AS1 RCHY1 NAAA PAQR3 HNRNPDL CCNI HPSE AFF1 ANXA3 SEC31A COPS4 CNOT6L RASGEF1B LIN54 TECRP1 USO1 BMP3 HELQ HNRNPD C4orf36 THAP9 SLC10A6 PRDM8 BMP2K MRPL1 THAP6 G3BP2 SDAD1	down	***
GO_SISTER_CHROMATID_SEGREGATION	0.0000000	0.0000000	0.8634154	0.4994604	2.247667	163	TRIP13 DDX11 DDX12P STAG3L2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 PRC1 NCAPD2 ZWINT CDT1 SPDL1 KIF23 STAG3 BOD1 BUB1 TOP2A MAP10 REC8 TPR KIF2C MAD1L1 CDCA5 HORMAD1 MAD2L1 DSCC1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 DIS3L2 NCAPG FEN1 SPAG5 MAD2L2 KLHL22 KPNB1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA AKAP8L ESCO2 ANAPC1 CENPK STAG3L4 CDC20 TUBG2 CHMP4C CDK5RAP2 CHTF8	up	***
BLUM_RESPONSE_TO_SALIRASIB_DN	0.0000000	0.0000000	1.0276699	0.4705938	2.246452	307	CPS1 SIM2 TRIP13 KIF20A CDC45 TROAP BUB1B NUP107 NEK2 CENPF TIMELESS PBK NDC80 BRCA1 IRS1 TTK SLC27A2 POLE STIL PLK1 AURKB CENPA PTTG1 AKR1C1 ESPL1 CDC6 SOX9 TPX2 CCNB2 MCM2 TYMS CDC25A MYBL2 COCH PRC1 ORC1 CCNF ZWINT ZNF107 LSM5 SCG5 RANBP1 HMMR EXO1 KIF23 CHAF1A MKI67 HLTF KIF15 PAFAH1B3 BUB1 FANCA TOP2A AURKA CBX3 POLA2 KIF2C RRM2 PRKDC PKM KIF11 GPSM2 MCM3 CHAF1B CDC25C MCCC2 SOX4 LIG1 ZNF443 RIPK4 SLC9A3R1 TOPBP1 CHEK1 ORC6 MAD2L1 SOX11 RAD51AP1 FNTB RGS4 SLC25A10 SKP2 PARP1 INCENP CDKN2C NUSAP1 PLOD2 CDK1 POLE2 GMNN E2F1 NCAPG NARF FEN1 EZH2 SPAG5 CBX1 RECQL4 RNASEH2A KPNB1 PIAS3 DNMT1 COL1A1 TUBG1 TACC3 TUBB2A KIF22 TK1 DTYMK HDAC1 GINS2 KIF20B POLD1 ENC1 CDC7 CDC20 ACLY RPA1 SRRT UPK1B MCM6 MCM5 SNRPD1 DDX23 SRSF1 SKAP1 MSH2 CCNA2 PRIM1 GTF3C2 RFC5 NME4 RAD51 CARHSP1 SRP9 PGAM1 VDAC3 TNS3 SMC2 NPTX1 MTHFD1 CDC25B UBE2C	up	***
JAEGER_METASTASIS_UP	0.0000020	0.0000710	0.6272567	0.6408249	2.245919	37	CENPF UCHL1 TUBB2B SPP1 GPI CDC6 NNT DTL GINS4 HLTF AURKA THBS4 KIF2C RRM2 PLOD2 MERTK NCAPG ADAM12 TACC3 IGHM	up	***
GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_DN	0.0000000	0.0000000	0.8513391	0.5016727	2.245123	156	TRIP13 CDC45 BUB1B IGF2BP3 MPP6 PSPH PBK BRCA1 GINS1 RACGAP1 E2F8 KIF14 AP1S1 PLK1 NUF2 CDCA8 CENPA TPX2 CCNB2 FIGNL1 UHRF1 MCM2 PRC1 DTL NCAPD2 NUDT1 KIF23 CEP55 KIF15 KNTC1 BUB1 SAE1 CLSPN RRM2 WDHD1 KIF11 MCM3 CDC25C CHEK1 THYN1 MAD2L1 AHCY DCTPP1 SPC24 DSCC1 BRIP1 ALDOA NCAPG2 CBX5 ANAPC5 CDK1 CENPH BIRC5 NCAPG NOP2 CENPP PA2G4 DLGAP5 TACC3 SNRPA AARSD1 ARL6IP4 ANP32E ATAD5 CDC7 PPP1R8 LRRC59 MCM6 LANCL2 ATAD2 TCERG1 CCNA2 SHCBP1 COX5B ARHGAP11A WDR76 SMC2 ZMAT2 EPSTI1	up	***
REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX	0.0000012	0.0000441	0.6435518	0.6766982	2.244790	31	CDC45 MCM10 PRIM2 POLE CDC6 MCM4 MCM2 ORC1 MCM8 CDT1 POLA2 MCM7 MCM3 ORC6 POLE2 GMNN CDC7 RPA1 MCM6 MCM5 PRIM1	up	***
chr8p22	0.0000653	0.0013489	0.5384341	-0.6987969	-2.243451	18	DLC1 ASAH1 ZDHHC2 SLC7A2 MSR1 RPL35P6 VPS37A RNA5SP256 MIR548V CNOT7 MICU3 PCM1 MTUS1	down	**
GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP	0.0000000	0.0000000	0.8513391	0.4977403	2.242410	165	HELLS CDC45 CCDC34 CENPF SRGAP3 BRCA1 TTK KIF14 POLE ASPM PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA ECT2 TPX2 CCNB2 FIGNL1 RBBP8 PRC1 XDH NCAPD2 CXCL10 HMMR MKI67 KIF15 BUB1 AUNIP TOP2A KIF2C MCM7 CLSPN RRM2 WDHD1 HOOK1 KIF11 MCM3 CDC25C LIG1 CHEK1 MAD2L1 NEB RAD51AP1 BRIP1 INPP4B INCENP CKS1B NCAPG2 PLOD2 CBX5 CDK1 CENPH NCAPG PSAT1 NEIL3 EZH2 ETFB OCIAD2 CCNE1 KIF22 ESCO2 LCLAT1 ATAD5 USP18 RPA1 MCM6 CKAP2 SUOX ANK3 CORO2A APOBEC2 CCNA2 PRIM1 DZIP3 PRR11	up	***
GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN	0.0000000	0.0000000	0.8390889	-0.4227778	-2.242200	182	SLC31A2 KMO HMOX1 TSPAN4 OSBPL1A FABP4 MNDA FBP1 CYP27A1 CAT LIPA ENG LPL GFOD1 AQP9 CLEC10A SLC15A3 CD9 FUCA1 IGSF6 PILRA FGR AVPI1 MAN2B1 CD33 SLC7A7 LMNA CLEC7A IFI30 ANPEP RNASE1 STOM SIRPA GRN TFEC APOC1 TUBB6 CEBPA PLBD1 LY96 CDKN1A ITGAX TM6SF1 INHBA BACE1 HCK C1QA VAT1 RAB31 HK3 CTSZ TYROBP ACSL1 RHOQ TNFSF13 SORT1 TIMP2 CD86 APLP2 CCR1 FCGRT TFPI RTN1 MS4A4A RIPK2 NLRP3 TBC1D1 SCPEP1 GLUL SIGLEC9 CTSC CREG1 LPAR6 PAPSS2 C1QB LHFPL2 TREM2 FTL S100A8 QSOX1 FPR3	down	***
GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN	0.0000000	0.0000000	0.8634154	-0.4198510	-2.241481	185	DENND5A ZC3H12C SNX10 LYL1 HSD17B11 LMO2 MYADM INPP5A CD9 WBP4 CD22 GGA2 ANXA1 SPG21 PTS UBL3 SLC7A7 ENTPD1 RAP1A MAP3K8 PBX3 MS4A1 SRGN UBE2D3 MCL1 RAB14 TUBB6 TIPARP EPB41L2 ARRB1 AHNAK MPEG1 RNFT1 KLF4 PLAUR ROCK1 PLBD1 FAM49B PDE8A PLEKHB2 EPS15 EVI2A HLA-DQA1 HCK SACM1L MTPN PKIG ASNSD1 LIMD1 RAB31 ETS1 SNX2 STX7 EEA1 CD83 NDST1 PLCG2 RHOQ CD74 STXBP3 TCF4 AP1G1 VAMP4 SBF2 ACADL ADAM10 PPID IST1 SPIB VPS4B ARIH1 S100A4 CD19 CTSC DNAJB9	down	***
SU_TESTIS	0.0000009	0.0000361	0.6594444	0.5915015	2.241147	52	BUB1B NEK2 COIL CCNB1 MPP6 TTK CCNB2 HMMR RPL39L BUB1 AURKA NUP155 SYCP2 KIF2C TEKT2 PHKG2 ABCB6 TOPBP1 GPR135 HSF2BP CDK1 EZH2 MTOR	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP	0.0000012	0.0000436	0.6435518	-0.4820324	-2.240030	77	CLDND1 ZBTB34 GPCPD1 ZCCHC2 CDC42EP2 RRAGC SPIRE1 KLF10 HIPK3 KLF6 SLC7A11 ZNF697 SPRY2 MYCT1 TIPARP DUSP3 CCDC82 RIT1 DUSP1 CREBRF SLC25A25 SGK1 JUN PTP4A1 GABARAPL1 ANKRD12 FBXO30 FAM126B RORA NRG1 SPOPL PIM3 EGR1 ZFP36 TNFSF18 CFLAR EMP1 PGF C15orf39 AGO2 DNAJB6 PRNP TNPO1 FGFR1OP2 NCOA3	down	***
GO_CELLULAR_RESPONSE_TO_LOW_DENSITY_LIPOPROTEIN_PARTICLE_STIMULUS	0.0000784	0.0015751	0.5384341	-0.7236746	-2.238966	16	PPARG LPL CDH13 CD9 CD36 SOCS5 FCER1G CD81 SREBF2 LDLR HMGCS1 ITGB1	down	**
PLASARI_TGFB1_TARGETS_1HR_UP	0.0000361	0.0008228	0.5573322	-0.5924109	-2.238868	32	EGR2 HBEGF KLF10 NR4A1 ZMIZ1 CSRNP1 SNAI1 ID2 SMAD7 HES1 WNT9A ID4 IL6 JUNB IER5 SPATA13 SPSB1 SERPINE1	down	***
GNF2_RFC3	0.0000010	0.0000375	0.6435518	0.6328671	2.236397	39	FOXM1 FANCI TIMELESS NDC80 ASPM MCM4 NCAPD2 RANBP1 HMMR TOP2A KIF11 MCM3 RAD51AP1 CKS1B CDK1 BIRC5 SSRP1 GINS2 SUPT16H PFAS MCM6 SNRPD1 CCNA2 SMC2 CENPE PAICS UBE2C ADSL MSH6 SMC4 CTPS1 MRPL35 RFC3 RFC4 ITGB3BP	up	***
NIKOLSKY_BREAST_CANCER_5P15_AMPLICON	0.0000012	0.0000440	0.6435518	0.7470803	2.236069	21	SLC9A3 TRIP13 CEP72 PDCD6 CCDC127 NDUFS6 PLEKHG4B SLC6A3 EXOC3 CLPTM1L SDHA SLC12A7 BRD9 MRPL36	up	***
REACTOME_DNA_STRAND_ELONGATION	0.0000018	0.0000639	0.6435518	0.6794206	2.236026	30	CDC45 PRIM2 GINS1 MCM4 MCM2 MCM8 GINS4 POLA2 POLD2 MCM7 MCM3 LIG1 DNA2 FEN1 GINS2 POLD1 RPA1 MCM6 MCM5 GINS3 PRIM1 RFC5	up	***
GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN	0.0000000	0.0000000	0.8390889	-0.4208283	-2.235402	179	ACP5 HMOX1 MNDA PTPRE LIPA EGR2 CD44 BACH1 CORO1C PLEKHA1 CLEC10A NCF2 CD9 SLC11A1 EPB41L3 SYNC FGR AVPI1 MMRN2 PLA2G7 SPG21 ARSB GM2A CLEC7A IFI30 HLX SIRPA RGCC TNS1 SPRY2 TMEM41B TFEC ATP6V1H PTPN12 CCL22 KIAA0513 DAB2 SLC7A8 CEBPA CDS2 PLEK DSE PI4K2A ARHGAP17 VAMP3 SGK1 CTSS C1QA TYROBP HOMER1 PPM1F RRAS TNFSF13 RIN2 SAV1 TSC22D1 CD86 CD81 APLP2 FCGRT PLEKHO2 MFSD12 CLCN6 SLC31A1 ELOVL1 RIPK2 TBC1D1 SCPEP1 TTC28 SYNPO2L KIF1B DOCK4 NR3C2 LPAR6 RNF13 ATP6V0A1 SERPINE1 C1QB BHLHE41 LHFPL2 FUS	down	***
GO_POSITIVE_REGULATION_OF_CYTOKINE_BIOSYNTHETIC_PROCESS	0.0000058	0.0001750	0.6105269	-0.5233744	-2.233801	51	EREG IL1A HMOX1 SPN IL1B TNFRSF8 CLEC7A HSPB1 TRAF6 PTAFR THBS1 PTPRC TLR4 CD80 IL6 PSEN1 TYROBP CD74 CD86 EGR1 WNT5A BCL10 AKAP12 CD3E IRF1 IRF4 CD4 EBI3	down	***
PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP	0.0000007	0.0000266	0.6594444	0.5827248	2.229359	54	FOXM1 TTF2 NDC80 AURKB CENPA MCM4 MCM2 MYBL2 NCAPD2 HMMR AURKA RAD54L TOPBP1 RAD51AP1 CAD BLM SKP2 CDKN2C CDK1 DNA2 EZH2 DNMT1 SNRPA CDC7 CDC20 RPA1 MCM6 MCM5 TCERG1 MSH2	up	***
FURUKAWA_DUSP6_TARGETS_PCI35_DN	0.0000004	0.0000177	0.6749629	0.5554890	2.228477	68	HJURP CCNB1 CENPF POLQ PBK RACGAP1 STIL MMP1 AURKB CENPA TPX2 CCNB2 MCM4 PRC1 DTL NCAPD2 SIPA1L3 MAP7 CEP55 AURKA WDR3 KIF2C KIF11 ORC6 BLM KNSTRN NUSAP1 NCAPG DLGAP5 KIF20B CKAP2 MCM5 TCHP PRMT5 CCNA2 PRIM1 RTEL1 SHCBP1 ARHGAP11A	up	***
FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN	0.0000015	0.0000539	0.6435518	0.6065657	2.227680	45	FOXM1 CENPF TIMELESS POLE MCM2 TTLL4 NUDT1 CHAF1A AURKA POLA2 KIF2C MCM7 KIF11 MCM3 BLM CKS1B CDKN2C CDK1 E2F1 RNASEH2A TK1 CDC20 MCM6 MCM5 CCNA2 PRIM1 NFRKB CAP2 RFC5 MTHFD1 CDC25B UBE2C POLRMT RNF126	up	***
GO_MICROTUBULE_MOTOR_ACTIVITY	0.0000002	0.0000084	0.6901325	0.5431318	2.225829	78	KIF1A KIF12 KLC3 KIF20A DNAH2 KIF18B KIF14 DNAH3 DYNC1I1 KIF27 DNAH14 DNAI1 KIF23 KIF15 KIF3B KIF2C WDR78 KIF11 WDR60 DNAH8 KIF3C DNAH11 DNAH6 KIF5A KIF19 KIF2A KIF7 DYNLL2 DNAH5 DNAH7 KIF22 KIF21A KIF20B KLC2 KLC4 WDR34 DYNC1LI2 KIF21B DNAI2 DYNC2H1	up	***
GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP	0.0000000	0.0000000	0.8266573	-0.4197347	-2.224821	181	CD300LF SWAP70 MCOLN1 PECAM1 SOWAHC LTA4H KCTD9 SH2D3C LMO2 TMOD3 BACH1 KIAA1109 INPP5A DYRK1A FUCA1 SLC11A1 HEG1 SLC44A2 ASAH1 RNF144B SLAIN2 GPBAR1 RAB14 EVI2B CYBRD1 MAP2K3 MTMR6 DENND6A REST PTPRC CDS2 PAPSS1 SFTPD CLK4 FCER1G MBD2 SLC6A6 N4BP1 UBASH3B MRVI1 CMTM6 ZDHHC20 RBP7 NEK7 CPEB4 HK3 OSTM1 NXPE3 SP3 PIK3R1 APH1B PRORSD1P RRAS ING3 KIAA0232 FPR2 DUSP5 ZBTB11 SOD2 ME2 SESN1 IER5 DHRS12 SCPEP1 DAPK1 DUSP7 P2RX1 DAZAP2 SPOPL MAN1C1 ZBTB16 DUSP6 KCNE1 LNPEP ITGB1 HEY1 CD79B GPR137B MAN1A1	down	***
GO_DNA_DEPENDENT_DNA_REPLICATION	0.0000000	0.0000001	0.8012156	0.5053599	2.224462	132	DDX11 CDC45 TICRR MCM10 CHEK2 TIMELESS POLQ PRIM2 GINS1 E2F8 DBF4B POLE CDC6 MCM4 MCM2 ORC1 LIG3 GINS4 CDT1 EME1 POLA2 POLD2 SMARCAL1 MCM7 MMS22L WDHD1 HELB MCM3 LIG1 EME2 ORC6 DSCC1 BLM RECQL5 POLN SSBP1 POLE2 RFWD3 GMNN DNA2 FEN1 RECQL4 CCNE1 DNAJA3 CHTF18 GINS2 LRWD1 POLD1 POLB ATAD5 CDC7 STOML2 HMGA1 RPA1 FANCM MCM6 MGME1 CHTF8 WRNIP1 MCM5 ZRANB3 GINS3 PRIM1 RTEL1 RFC5 NUGGC RAD51 PNKP TONSL BCL6	up	***
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP	0.0000000	0.0000001	0.7881868	0.5065400	2.217229	128	KIF20A TFAP2A-AS1 HJURP CDC45 BUB1B CCNB1 CENPF TTK IQGAP3 GTSE1 GMPS ASPM PTTG1 CDC6 TPX2 CCNB2 UHRF1 MCM4 PRC1 SHMT2 XPOT PVT1 SPDL1 C19orf48 CHAF1A MKI67 BUB1 TOP2A AURKA SAE1 RRM2 LMNB1 SLC35G2 KIF3C BRIP1 AFAP1L2 NUSAP1 ASF1B BIRC5 NCAPG LARP1 SPAG5 RNASEH2A MZT2A MZT2B GRAMD1A DLGAP5 SNRPA MTA3 TK1 GEMIN5 ANAPC1 PWWP2A KPTN RAB15 URB1 TTLL6 ATAD2 AP2S1 PRR11 SCNM1 ANK2 WDR76 LINC00839 CENPE PAICS PCBD1 UBE2C NUP210 NCAPH MLLT11 ZNF37BP	up	***
MISSIAGLIA_REGULATED_BY_METHYLATION_DN	0.0000000	0.0000006	0.7477397	0.5168687	2.214594	108	FOXM1 CDC45 BUB1B NEK2 CENPF CYP2J2 KIF14 GMPS ESPL1 CDC6 TYMS PRC1 ZWINT CDT1 RANBP1 KIF23 MKI67 KNTC1 AURKA ITGB4 POLD2 MDFI PRKDC LMNB1 CDC25C LIG1 CHEK1 FBL CAD CDKN2C NUSAP1 CDK1 GMNN EZH2 SEMA3A RNASEH2A NRGN DNMT1 DLGAP5 HMGB1P10 SNRPA KIF22 TK1 DTYMK ENOSF1 CENPM MCM5 RCC1 CCNA2 PRIM1 RFC5 MICU1 SMC2 CENPE PAICS UBE2C NCAPD3 NCAPH KIAA0586 TMPO MECOM MSH6 SHMT1 DCLRE1A RAB26 HNRNPAB POLD3 SMC4 STMN1 HNRNPA1 PCDH7 TRIM28 RFC4	up	***
GO_ENDOTHELIAL_CELL_DEVELOPMENT	0.0000085	0.0002446	0.5933255	-0.5225625	-2.214517	50	SOX18 PECAM1 IL1B RDX RAPGEF2 CDH5 ENG MYADM HEG1 PDE2A RAP1A PDE4D ROCK2 ROCK1 TJP1 CLDN5 CLIC4 ARHGEF26 ADD1	down	***
chr5p15	0.0000012	0.0000449	0.6435518	0.5834490	2.214040	53	SLC9A3 TRIP13 CEP72 PDCD6 CCDC127 SDHAP3 NDUFS6 PLEKHG4B SLC6A3 EXOC3 CLPTM1L MIR4458HG SDHA CCT5 MYO10 NSUN2 CMBL SLC12A7 BRD9 MRPL36 DNAH5 DAP SRD5A1 SNHG18 TRIO	up	***
GO_DNA_REPLICATION_INITIATION	0.0000023	0.0000787	0.6272567	0.6435028	2.213946	34	CDC45 TICRR MCM10 PRIM2 POLE CDC6 MCM4 MCM2 ORC1 CDT1 POLA2 MCM7 MCM3 ORC6 POLE2 CCNE1 LRWD1 MCM6 WRNIP1 MCM5 PRIM1	up	***
GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN	0.0000000	0.0000000	0.8634154	0.4901804	2.210782	169	TRIP13 HELLS KCNK5 CDC45 GPT2 CCNB1 UBE2T PHGDH CDCA7 METTL1 TTK HILPDA TOMM34 ACAD9 ESPL1 RBBP8 UHRF1 MCM4 CYP27B1 DTL ACY1 LIG3 SHMT2 ZWINT AGK C19orf48 CHAF1A KIF3B AURKA POLD2 TTLL12 CHEK1 ORC6 PFKP TIMM50 FNTB BLM DDX56 THOP1 KNSTRN DDX51 POLE2 UCK2 NPM3 TRAP1 EZH2 NOP2 PA2G4 POFUT1 PDCD11 MRPS34 MAPK13 DPH2 MYBBP1A MFSD2A GINS2 MRPL4 SPAG1 TIMM13 CDC20 NPRL3 RRP9 BCL2L1 NOL6 UTP20 NOC4L CLUH GINS3 IL12RB2 SLC1A5 NEFH MED27 FARSA SUV39H2 NTMT1 ABCF2 ZWILCH TRIP6 ST20 SNX8 LIF POLR1A ALG1 PCBD1 TIMM44 SNRPC SFXN4 KCNK6 C9orf40 F5	up	***
MODULE_96	0.0000672	0.0013813	0.5384341	-0.6070706	-2.209447	27	FCN1 OLR1 ASGR1 FCN3 CLEC3B THBD CHIT1 CLEC10A CD22 SELL SELP SFTPD GFPT2 LGALS2 LGALS3 CLEC2B	down	**
GO_PATTERN_RECOGNITION_RECEPTOR_ACTIVITY	0.0002351	0.0039454	0.5188481	-0.7242210	-2.209210	15	FCN1 MARCO CD36 CLEC7A PTAFR LY96 TLR4	down	**
GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_DN	0.0000000	0.0000000	0.8012156	0.4961681	2.208508	148	TRIP13 KIF20A HJURP MCM10 TROAP BUB1B NEK2 PRTFDC1 POLQ UBE2T KIF18B IFI27L1 DEPDC1B PLK1 NUF2 CENPA PTTG1 ESPL1 CCNB2 NBR2 MCM2 GLDC LIME1 COQ3 CLDN1 CEP55 RPL39L MKI67 EMC9 TSGA10 LGMN AURKA KIF2C CDCA5 KISS1R RAD54L MAD2L1 CKAP2L DPY19L1P1 MGLL DDX51 TMEM106C PLOD2 ASF1B EPHA1 BIRC5 C1orf112 PSAT1 NEIL3 FEN1 SSX2IP SPAG5 DIAPH3 ITGA2B NRGN CCNE1 DLGAP5 ESCO2 LIPC GNAZ DENND5B	up	***
FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP	0.0000000	0.0000000	0.8140358	0.4992869	2.208076	141	SLCO5A1 HJURP PARPBP CCNB1 CENPF POLQ UBE2T MND1 NDC80 BRCA1 ANLN ESPL1 RGS6 CDC6 TPX2 CCT6A NCAPD2 ZWINT LSM5 CLPTM1L MELK KIF23 CEP55 CHAF1A ZFYVE27 KIF15 KNTC1 TOP2A ODF2 KIF2C WDHD1 ZNF146 FANCD2 LMNB1 BRD9 CHEK1 DSCC1 BRIP1 BLM IKBKB NCAPG2 NUSAP1 POLE2 GMNN NCAPG FEN1 DLGAP5 CHTF18 ITFG2 DAP3 SAP30 ATAD5 CENPK EP400 FANCM THOC5 CKAP2 SNRPD1 MRPL51 ATAD2 RPS26 CCNA2 ZNF93 ANK2 ARHGAP11A SMC2 CENPE	up	***
BURTON_ADIPOGENESIS_1	0.0000754	0.0015250	0.5384341	-0.6018770	-2.207651	28	WEE1 THBD LITAF FOXC2 RHOB ID3 PER1 MAFF SLC25A25 IL6 SGK1 TSC22D1 IRS2 ETS2 CEBPD NR4A2 DNAJB4 NFIL3 DUSP2	down	**
ZHANG_ANTIVIRAL_RESPONSE_TO_RIBAVIRIN_DN	0.0000241	0.0005854	0.5756103	-0.5398412	-2.205864	41	NCF2 ATP2B1 CAV2 GATA3 UBE2D3 PPP3CC SOCS2 CCL3 AXL CCL4 ARL4A JUN PTGER2 TNFRSF9 FOXO3 IRF5 GEM FGF2 RAPGEF3 CDC14A SERPINE1 CENPC CFLAR CYP1B1 ZFHX3 RGS20 RALGDS DUSP10	down	***
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP	0.0000000	0.0000000	0.8266573	0.4895877	2.205681	165	FOXM1 HELLS KIF20A CDC45 BUB1B CCNB1 UBE2T GGCT NDC80 BRCA1 CDCA7 HILPDA ANLN ASPM STIL PLK1 YEATS4 CENPA ECT2 ESPL1 CDC6 UHRF1 MCM4 MCM2 TYMS PRC1 DTL ZWINT HMMR EXO1 KIF23 CEP55 MKI67 KNTC1 BUB1 TOP2A NUP155 MCM7 CENPW RRM2 CDCA5 KIF11 MCM3 ORC6 MAD2L1 DSCC1 PKMYT1 BLM IDH2 CKS1B ASF1B CDK1 UCK2 GMNN POLR3K E2F1 FBXO41 STEAP1 SAPCD2 RECQL4 TUBG1 TACC3 TUBA8 TUBBP5 FHL2 ENC1 CDC7 TNK1 MCM6 PLEK2 MCM5 ANKRD1	up	***
BASSO_CD40_SIGNALING_UP	0.0000003	0.0000127	0.6749629	-0.4627138	-2.204154	88	PHACTR1 IL1B PTPRE SIK1 CD44 BCL2A1 NCF2 SH2B3 MAP3K8 IFI30 LITAF SRGN ARHGEF2 CD58 STAT5A CCL22 CCL3 LAPTM5 CCL4 PLEK HLA-DQA1 SNN NCKAP1L RAC2 JUNB CCR7 CD83 GPR183 CD74 IRF5 EHD1 LRRC32 RXRA ICAM1 TNFAIP8 TRAF1 NFKBIA TNFSF9	down	***
GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP	0.0000000	0.0000000	0.8266573	0.4848113	2.203496	178	CDC45 BDH1 FANCI BUB1B NEK2 CCNB1 CENPF TIMELESS TTF2 NDC80 SORD PHGDH TTK CDK4 SLC27A2 PTTG1 GPI ESPL1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 ALDOC SHMT2 XPOT NCAPD2 CDT1 NME1 RUVBL2 HMMR KIF3B EEF1E1 TOP2A CCT5 AURKA POLD2 KIF2C RRM2 PKM KIF11 MCM3 AHCY RAB13 RAD51AP1 ALDOA THOP1 CKS1B TMEM106C CDK1 POLE2 NPM3 EZH2 TUBG1 GNPAT GALK2 RAD51D TK1 ASNS SAP30 ZBTB7B CDC7 AHCYL1 STAMBP FAM161A HAX1 FARSA PYCR1 CCNA2 PRIM1 VDAC1 ATOX1 VDAC3 SMC2 MTHFD1 TP53 PAICS BCAT2 ENO1 MUC1 NCAPH CYB5B CFI SRM BAG2 NIT1 GSTP1 VLDLR TOMM40	up	***
GNF2_SELL	0.0000377	0.0008551	0.5573322	-0.5315580	-2.203260	43	LRRFIP1 HSD17B11 MYD88 DPEP2 MCL1 EVI2B CASP1 LAPTM5 SELL CD53 CMTM6 ARHGDIB JUNB GMFG ARRB2 ACAP2 ICAM3 PAK2 THEMIS2 DAZAP2	down	***
VECCHI_GASTRIC_CANCER_ADVANCED_VS_EARLY_DN	0.0000000	0.0000008	0.7477397	0.5166674	2.202622	107	ATP10B CPS1 RHPN2 MYEOV ADH1C GMDS EPN3 HBA1 SULT1C2 PRSS2 ADRA2A PTPRN2 GCNT3 TFF3 BCL2L15 SDHAP3 AKR1C1 SLC4A4 HBB LIG3 VILL GSDMB CAPN13 HMMR CLDN15 KCNE3 VPS28 REEP6 ALDOB STEAP3 DDT SNRNP25 DPP3 C9orf152 ESCO2 FXYD3 ZBTB7B CENPV GOLM1 ENTPD3 LPCAT4 XRCC4 TMEM45B RER1 TMC5 BLVRB SYBU ETHE1 ALDH3A1 RBM19 PCBD1 CYSTM1 CAPN9 MUC1	up	***
LINDSTEDT_DENDRITIC_CELL_MATURATION_D	0.0000038	0.0001226	0.6272567	-0.5129957	-2.202466	55	ACP5 RBMS2 PTPRE EGR2 CLEC10A MKNK1 NCF2 IGSF6 ANXA1 NAAA ITGA5 MTMR6 CCL22 DAB2 TPP1 ITGAX PTGER3 ARHGDIB AQP3 RAB31 NPR1 ATP6V1A CCR1 FCGRT CLEC2B CCNH	down	***
GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP	0.0000000	0.0000000	0.8266573	-0.4141873	-2.202225	175	MCOLN1 PPARG LPL GFOD1 CORO1C GPCPD1 TBC1D7 ZCCHC2 TBC1D2 TRIB1 TXNIP EIF4A1 CNST FBXO7 RRAGC LINC01010 IFI30 CRTAM TMEM38B ATP6V1B2 RHOB FBXL5 FABP5 MOAP1 ACSL3 DAB2 TNFSF15 MAP1LC3B TMED5 STX3 ATP6V1D TMBIM1 ATF3 PPP2R5A UBASH3B FKBP15 CD300LB EFR3A PI4K2A MMP19 HEXB CLN8 NRROS TMEM9B BCAR3 SGK1 SH3BP5 HIC1 TMEM251 SNX9 KLF2 RNASEK CD164 TGIF1 COL15A1 LGALS3 TMEM70 BRI3 CCR1 GNA13 PLEKHO2 AMD1	down	***
RPS14_DN.V1_DN	0.0000000	0.0000000	0.8266573	0.4928272	2.200469	152	TRIP13 KIF20A MCM10 PBK DEPDC1 SLC25A21 TBRG4 TUBB2B AGFG2 E2F8 PLK1 ECT2 ESPL1 CDC6 CCNB2 MYBL2 PRC1 ORC1 EXO1 ZNF74 NLE1 KIF23 MKI67 KIF15 TRIM29 SPTB NUP155 SLC29A2 LARS2 KIF2C CAD ERCC2 PES1 GEMIN4 INCENP ISOC2 KIF5A MRPS2 PSAT1 STEAP3 MYO19 TUBG1 DLGAP5 TUBB2A TSPO2 TK1 COLEC11 IL15RA GINS2 SRD5A3 LRRC20 ASNS ELMO3 POLD1 CDC20 DGCR11 SIRT4 GPATCH4 CDR2 MCM5 NEFH SH3TC2 ATAD2 EPCAM KLHL7 PYCR1 SUV39H2 MSH2 IL7 TUBGCP4 ZWILCH ARHGAP11A LLPH RPUSD2 CENPE RRS1 NCAPH MRTO4 SRM BAG2 MRPL12 FBXO5 TLN2 LGR4	up	***
FLORIO_HUMAN_NEOCORTEX	0.0000011	0.0000422	0.6435518	0.8320482	2.199656	13	FUT6 FAM177B ZNF221 C20orf197 APOL1 MAP1LC3C SP140L LAMB4 POU5F1B	up	***
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN	0.0000000	0.0000000	0.8140358	0.4936178	2.199369	147	HMGA2 TRIP13 EYA1 FANCI BUB1B CENPF TIMELESS PRIM2 BRCA1 TTK KIF14 AURKB SIX1 PTTG1 ESPL1 TPX2 CCNB2 MCM2 LIG3 SRPK1 SHMT2 XPOT MYL6B NME1 MELK KIF23 CHAF1A MKI67 TOP2A AURKA KIF2C MPHOSPH9 KIF11 LMNB1 CDC25C SALL2 TOPBP1 DNAJC9 MAD2L1 PFKP BLM FADS2 MEOX1 DLG5 PARP1 CKS1B CBX5 CDK1 UCK2 CCT3 UNG FEN1 EZH2 NUP205 SPAG5 RNASEH2A ILF2 DLGAP5 SSRP1 ASNS CKAP5 CDC20 MCM6 DDX23 CACNB3 TCERG1 MSH2 PRIM1 MLXIP GTF3C2 RFC5	up	***
GSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN	0.0000000	0.0000000	0.8266573	0.4875858	2.194229	163	TRIP13 TP63 DDX11 FOXM1 HELLS KIF20A CDC45 TROAP NEK2 CCNB1 CENPF PHGDH GINS1 E2F8 IFT122 KIF14 ASPM TPX2 CCNB2 TYMS CDC25A PRC1 PLS1 DTL ZWINT DZANK1 MELK EXO1 CHAF1A RPL39L MKI67 KIF15 AUNIP TOP2A AURKA POLA2 KIF2C RRM2 PRKDC RHOBTB3 KIF11 RAD51AP1 PKMYT1 BRIP1 REPIN1 NUSAP1 TMEM106C ASF1B CDK1 POLE2 TNFRSF21 UCK2 GMNN NCAPG EZH2 SPAG5 ABCA4 DNMT1 DLGAP5	up	***
GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP	0.0000000	0.0000001	0.8012156	-0.4137171	-2.192925	181	RAB11FIP1 PECAM1 LTA4H LIPA LRRFIP1 HSD17B11 BAIAP2 C5AR1 YPEL5 MANBA NEDD9 AGTPBP1 CASP9 TACC1 ASAH1 CLEC7A RAB33B NR4A1 CD37 RHOB FLI1 EVI2B SRSF5 KIAA0513 KLF4 ITM2B DENND3 PLBD1 COTL1 TLR4 CD302 DUSP1 EVI2A SPIN1 MYLIP ELF1 SF3B1 OSBPL9 IFNGR1 PTGER4 PIK3R1 RASSF2 SNRK PPM1F CELF2 KLF2 RUNX3 PHF3 ZBTB1 GOLGA8H CBFA2T3 CD86 MAP3K2 CSDE1 ADPGK RGS2 TSPO JUND GPX3 CCDC69 IQSEC1 CEBPD ALDH2 SCPEP1	down	***
TANG_SENESCENCE_TP53_TARGETS_DN	0.0000019	0.0000659	0.6435518	0.5816853	2.191903	51	KIF20A NEK2 PBK TTK RACGAP1 AURKB CENPA PTTG1 TPX2 CCNB2 CDC25A PRC1 KIF23 BUB1 TOP2A KIF11 LMNB1 NUSAP1 IGFBP5 CDK1 BIRC5 EZH2 SPAG5 NRGN TK1 KIF20B CDC20 IL12RB2 NUP62 CCNA2 CENPE UBE2C PDP1	up	***
GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN	0.0000000	0.0000000	0.8140358	-0.4108506	-2.191308	183	ARHGAP31 SWAP70 EDNRB HVCN1 ZC3H12C IL1B PTPRE EGR2 HCAR2 CCRL2 LONRF1 FXYD2 SLC15A3 STX11 ALAS1 BCL2A1 PILRA SEMA6D HBEGF ADAM17 PLXNA2 ANXA5 SERPINB9 NFE2L2 PDGFA RHOB SLC7A2 SLC7A8 VASP KLF7 CXCL2 ATF3 ID2 DUSP1 PLEK HTT UBASH3B KPNA3 TLL1 RASGEF1B PROCR IL6 IL2RB MTMR14 PLK3 JUNB RCAN1 SKIL PSTPIP2 MALT1 TAGLN2 ACSL1 SMPDL3B GSAP FPR2 FEM1B DUSP5 CD86 GPR84 PLEKHO2 GEM WDR1 RIPK2 NLRP3 TRAF1 EDN1 TNFSF9 NRP2 ATF4 SLC16A10 HERPUD1 JDP2 EGR1 CD70	down	***
RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP	0.0000000	0.0000000	1.0376962	-0.3796644	-2.191276	369	CXCL3 EREG ACP5 KMO SC5D CD52 IL1A FCN1 PHACTR1 PECAM1 OSBPL1A CD55 IL1B LTA4H FBP1 CYP27A1 SNX10 DCSTAMP LPXN RDX PID1 FYN LY86 LMO2 CCRL2 AQP9 MYD88 C5AR1 ALAS1 NEDD9 CD9 LAMP1 EPB41L3 TEX2 TMX4 DPEP2 PLA2G7 MCTP1 HBEGF SLC7A7 ASAH1 ENTPD1 GM2A TNIP3 ANXA5 KLF10 SLC7A11 STOM LAIR1 RGCC AKT3 CRTAM CES1 ZFYVE16 TCF7L2 TFRC ATP6V1H APOC1 FBXL5 IL10 CFD TLE4 KCNMA1 CASP1 KLF9 DAB2 DENND3 MYO15B ITPK1 CTSD CCL3 CDS2 CTBS SELL TM6SF1 DNTTIP2 PINK1 MATK ZNF706 HLA-DQA1 CRIM1 MAPRE2 NCOA1 HEXB SGK1 PDCD6IP CD48 C1QA MITF VAT1 SH3BP5 LTBP2 TREM1 TMEM251 ZNF804A PTGER2 ATP13A3 CXCL5 SLC3A2 RHOQ ICAM2 NKG7 RIN2 EMC7 TIMP2 CHPT1 TFEB TSC22D1 GALC CD81 APLP2 SOD2 LGALS3 CCR1 KYNU DECR1 ETS2 IL18 CCDC69 SLC31A1 CALHM2 MS4A4A ATP9B CDKN1C SIK3 NLRP3 TBC1D1 FDX1 BCAT1 DOCK4 MT2A GRPEL1 ARFGAP3 ACAT1 SPHK1 DMXL2 ATP6V0A1 TMEM184C EGR1 SERPINE1 BHLHE41 DUSP6 NR4A2 CX3CR1 CLEC4E LHFPL2 AOAH ITGAL	down	***
chr12q15	0.0000070	0.0002059	0.6105269	0.7071863	2.189814	24	KRT8P39 MDM1 NUP107 CPSF6 RAB3IP PTPRR YEATS4 SLC35E3 KCNMB4 CCT2 FRS2 MYRFL MDM2 DYRK2 CNOT2 HNRNPA1P70 IFNG-AS1	up	***
chr22q11	0.0000000	0.0000001	0.8012156	0.4943894	2.186867	140	IGLV4-69 ZDHHC8P1 POM121L9P IGLV3-27 CDC45 CECR7 DGCR5 IGLV1-36 ZNF280B DGCR9 CABIN1 IGLV3-9 DGCR8 IGLC7 KRT18P5 RAB36 TOP3B RANBP1 IGLV3-10 ZNF74 DDTL IGLV1-44 SLC2A11 PEX26 TRMT2A IGLV1-40 PPIL2 PI4KAP1 GNB1L RN7SL812P LINC00896 DDT KLHL22 IGLV7-43 LZTR1 DGCR6 TBX1 IGLV6-57 GGT2 YDJC C22orf15 SLC25A18 HIRA TUBA8 IGLV1-47 GNAZ RGL4 USP18 DGCR11 ARVCF GGT3P PRODH GGT5 PI4KA IGLL5 PI4KAP2 MICAL3 ZNF70 SERPIND1	up	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN	0.0000000	0.0000000	0.8012156	-0.4127203	-2.186580	173	ACP5 FCN1 CD101 SIGLEC16 HHEX FABP4 MNDA LTA4H FBP1 GPR65 LIPA INPP5K SAMHD1 CD1C CD9 FUCA1 TEX2 GGA2 AVPI1 TXNIP CD36 TACC1 CLEC7A ZNF503 REV3L RNASE1 ABHD6 C1orf162 EVI2B TIMM10B PPT1 KIAA0513 SLC46A2 CD302 CPT1A RAP1GDS1 MPC1 UBASH3B CD300LB PRCP PDK4 RBP7 SLCO2B1 OASL UTRN GLUD1 LPCAT2 VMO1 GAS2L3 FOS SORT1 KIAA0232 CD1D GALC MFNG GNA13 MACF1 PLA2G15 SLC31A1 CALHM2 SLC25A20 PIP4K2A ARHGAP18 METTL7A CD1E DOCK10 RHOT1 LPAR6	down	***
PID_TGFBR_PATHWAY	0.0000123	0.0003324	0.5933255	-0.5117078	-2.184007	51	CAV1 NEDD4L TGFBR3 TGFBR2 RHOA PPP2R2A SPTBN1 ZFYVE16 DAB2 SMAD7 TGFB2 PPP2CA PPP1R15A SKIL GRB2 PPP2CB TGFB1 PARD6A ZFYVE9 SMAD2 FKBP1A ARRB2 DACT2 TAB2 ITCH SMAD4	down	***
BROWN_MYELOID_CELL_DEVELOPMENT_UP	0.0000000	0.0000016	0.7337620	-0.4343301	-2.183921	127	SLC31A2 EREG CD52 ABHD5 OLR1 IL1B CD44 EMCN C5AR1 SLC15A3 BCL2A1 IL1RN FGR CD33 SGMS2 ANXA5 ANPEP HLX STOM SIRPA GRN MCL1 ATP6V1B2 MPEG1 PLAUR DAB2 MYO1B ITGAX ID2 CCND2 DSTN SLC6A6 DEGS1 HEXB HCK CD80 CTSS PGD TYROBP PLK3 JUNB CSTA PSTPIP2 CAP1 FPR2 CCR1 GSTM5 CEBPD SP100 SOAT1 PLGRKT HEBP1 IQGAP1 CNN2 EGR1 AOAH TREM2 ZYX FPR1 NFAM1 QSOX1	down	***
ANDERSEN_CHOLANGIOCARCINOMA_CLASS2	0.0000000	0.0000000	0.8140358	0.4901382	2.183866	147	DKK1 STYK1 GPR87 LEMD1 SCIN MYEOV C1GALT1 BIK PPP1R1B CDH17 GALNT6 GCNT3 PTPRR SIX4 PPP1R14D GPR35 TTK BCL2L15 ANLN FA2H TPX2 CCNB2 VSTM2L ANKRD22 HOXB7 FERMT1 ASPHD2 VILL KRT15 EPS8L1 TJP3 ITGA2 SLC6A20 CEP55 KCNN4 LAMC2 CBLC KIF15 BUB1 AUNIP TOP2A AURKA SLC4A11 KIF11 MYO1A GJB3 CDH3 SAPCD2 TSPAN1 ST14 COL1A2 DLGAP5 DTX2 CTSV PKP3 KRT19 FXYD3 COL11A1 CDC20 TFCP2L1 IGFL2 PLEK2 CYP2S1	up	***
GNF2_IL2RB	0.0000145	0.0003848	0.5933255	-0.5795757	-2.180894	34	CTSW GNPTAB CCL4 XCL2 PRF1 KLRD1 MATK CD160 IL2RB PTGER2 CD7 TBX21 CST7 RUNX3 NKG7 IL18RAP KLRF1 CX3CR1 PRKCH S1PR5	down	***
GO_DNA_CONFORMATION_CHANGE	0.0000000	0.0000000	0.8634154	0.4714249	2.180249	203	HMGA2 DDX11 HELLS DDX12P HJURP RUVBL1 CDC45 CCNB1 POLQ PIF1 GINS1 CABIN1 TSPYL5 CENPA SOX9 MCM4 MCM2 RAD54B MCM8 MIS18A GINS4 SRPK1 NCAPD2 TOP3B RUVBL2 CHAF1A TOP2A CENPL GPER1 TPR SMARCAL1 MCM7 CENPW CDCA5 HELB RAD54L MCM3 CHAF1B CHD6 CENPO DSCC1 BRIP1 BLM ERCC2 MNAT1 RECQL5 PARP1 NCAPG2 NUSAP1 ASF1B CDK1 SSBP1 CENPH NAV2 NCAPG DNA2 RECQL4 CENPP HIRA CHTF18 CENPQ AKAP8L GINS2 NOC2L CHD5 RAD50 CENPK CENPV CENPM HMGA1 RPA1 MCM6 CHTF8 CENPT MCM5 ZRANB3 IGHMBP2 BANF1 RTEL1 RFC5 RAD51 CHMP1A CHD3 SIRT6 SMC2 XPC TP53 NCAPD3 DDB2 SART3 ERCC3 NCAPH ACIN1	up	***
WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP	0.0000000	0.0000000	0.9214260	0.4616511	2.177074	246	TSPAN8 UNC5CL STYK1 C1GALT1 GMDS ZMYND8 FRK TOX3 PLEKHH1 GALNT4 FA2H EIF2B5 BAIAP2L1 C4orf19 AGR2 AACS PLS1 ACY1 CIB1 SRPK1 TJP3 MANSC1 CLPTM1L BZW2 SYTL2 GFPT1 BPHL MYO10 SLC2A10 ICA1 TTC22 TTLL12 CD24 KDELR2 CC2D1A TMEM63A BACE2 EHF RABEP2 FUT2 FLNB MGLL UQCR11 DYRK2 ESRP1 ABHD17C ETFB NET1 GIPC1 ZGPAT ST14 GSS LLGL2 MRPL52 DOK4 C9orf152 HDAC1 HIP1R GALNT3 SLC22A23 GSTK1 SGSM3 FXYD3 TMEM30B JTB GALNT7 NADSYN1 DHTKD1 CENPV ACBD5 TSTA3 ERBB3 POP7 CHMP4C ABCC3 MRPL41 NOSIP LSM7 SLC35A3 OVOL2 MVP TC2N EPCAM DDAH1 MRPL14 C19orf33 SMARCA4 HDLBP TMC5 CANT1 DOHH MLLT6 ARRDC1 LRRC8B CHMP1A MROH1 TRAK1 AURKAIP1 UQCRQ EIF4G1 RAB25 GOLGA2 PPIA EPHB4 SART1 MUC1 RABL6 NQO1 CAMK2N1 PLAC8 MED16 RNF126 MFSD9 GSTP1 TMEM259 CRB3 PSMB10 TOMM40 MECOM MARVELD2 STARD10 MPST	up	***
HOLLERN_EMT_BREAST_TUMOR_DN	0.0000000	0.0000016	0.7337620	0.5080469	2.176796	108	RHPN2 LTF CEACAM1 KLC3 PLEKHH1 EFNA3 ILDR1 SPINT2 LSR GRB7 KRT15 EPS8L1 TJP3 CLDN1 MAP7 STAP2 CBLC TMEM184A RNF43 AP1M2 CD24 RIPK4 SPINT1 EHF DDR1 GRHL2 WWC1 NRTN EPHA1 ESRP1 SDR42E1 CDH3 TMEM79 MYO5B IRF6 ST14 ARHGEF16 LLGL2 PKP3 KIF21A HIP1R SPTBN2 ELMO3 EPB41L4B FXYD3 TMEM30B TNK1 ERBB3 C1orf56 CDCP1 EPCAM PRSS8 CDH1 GRHL1	up	***
GO_BLOOD_VESSEL_ENDOTHELIAL_CELL_PROLIFERATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0003131	0.0050619	0.4984931	-0.6171394	-2.176661	24	ACVRL1 HMOX1 GATA2 BMPER MIR27B MIR146A NRARP THBS1 MIR24-2	down	**
BURTON_ADIPOGENESIS_PEAK_AT_24HR	0.0000049	0.0001538	0.6105269	0.6174371	2.173904	38	KIF20A CCNB1 LCN2 RACGAP1 ANLN AURKB PTTG1 PRC1 MELK HMMR BUB1 TOP2A CENPL AGT CDC25C DCTPP1 CAD NUSAP1 CDK1 RANGAP1 KIF22 TK1 CDC20 SRSF1 EXOSC5 CCNA2 SNRNP70 UBE2C	up	***
HINATA_NFKB_IMMU_INF	0.0000799	0.0016029	0.5384341	-0.7453313	-2.171170	13	CXCL3 OLR1 IL1B PTX3 NFKB1 CXCL2 IL6 CD83 ICAM1 NFKBIA	down	**
GO_MITOTIC_SISTER_CHROMATID_SEGREGATION	0.0000000	0.0000002	0.7749390	0.4908123	2.167448	137	TRIP13 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 PRC1 NCAPD2 ZWINT CDT1 SPDL1 KIF23 BOD1 BUB1 MAP10 TPR KIF2C MAD1L1 CDCA5 MAD2L1 DSCC1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 DIS3L2 NCAPG SPAG5 MAD2L2 KLHL22 KPNB1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA AKAP8L ANAPC1 CENPK CDC20 TUBG2 CHMP4C CDK5RAP2 CHTF8	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN	0.0000065	0.0001930	0.6105269	0.5803425	2.164420	48	ELOVL6 BUB1B PAGR1 NDC80 E2F8 PLK1 ESPL1 CCNF MKI67 KIF15 AURKA ZNF174 TTLL12 PPP1R35 SPC24 PML SKP2 CDKN2C PPIL2 EXOSC2 NEIL3 TACC3 ENOSF1 PRMT7 CCDC51 NIF3L1 GEMIN6 CDC20 CCNA2 ZNF93 POLR3B DHRS3 RRS1 NR2F6 FAM111B TMPO XAF1	up	***
AMIT_SERUM_RESPONSE_60_MCF10A	0.0000158	0.0004131	0.5756103	-0.5086660	-2.163899	52	EREG TRIB1 IER2 BMP1 HBEGF MAP3K8 RHOB CYBRD1 KLF7 PNRC1 INHBA SGK1 RCAN1 PTGER4 MBNL2 COBLL1 TGIF1 C1orf116 DUSP5 IRS2 ETS2 CCL20 PDLIM5 PMAIP1 EGR1 PXMP4 NR4A2	down	***
GO_POSITIVE_REGULATION_OF_PHAGOCYTOSIS	0.0000066	0.0001946	0.6105269	-0.5037726	-2.162868	55	SIRPB1 CD300LF PPARG GATA2 IL1B GAS6 SLC11A1 CD36 RAP1A CLEC7A PTX3 SIRPA PTPRC SFTPD FCER1G LYAR NCKAP1L IL2RB RAB31 RAPGEF1	down	***
REACTOME_INTERLEUKIN_3_INTERLEUKIN_5_AND_GM_CSF_SIGNALING	0.0000819	0.0016337	0.5384341	-0.5292113	-2.162797	40	FYN CBL CRK STAT5A HCK IL2RB JAK1 RAPGEF1 PIK3R1 GRB2 PRKACA YWHAZ UBB TEC CSF2 CSF2RB IL5 PIK3R3 UBC JAK2 SYK UBA52 PIK3CA PTPN11 LYN	down	**
GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP	0.0000000	0.0000000	0.8266573	0.4785316	2.162220	172	TRIP13 RUVBL1 CDC45 KIF18B PIF1 TBRG4 BRCA1 DEPDC1B MRPL46 IQGAP3 ASPM STIL ECT2 CCNB2 RAD54B TYMS UMPS CA12 SHMT2 NCAPD2 NME1 NDUFB8 KIF23 MKI67 QTRT1 BUB1 CCT5 KIF2C CLSPN MRPL3 MRPL27 PASK MCM3 LIG1 ZNHIT1 C7orf50 CBY1 DSCC1 PSRC1 NUSAP1 ASF1B POLE2 CENPH NUDT2 PSMB5 DNA2 PSAT1 RECQL4 DLGAP5 TAPBPL TACC3 SNRPA LMNB2 MNS1 GALNS ANP32E SGSM3 CNDP2 CDC7 NIF3L1 CDC20 STOML2 LRRC59 GPATCH4 BCL2L1 FANCM MCM5 TMEM147 NOC4L FFAR2 TSR1 NUP62 LRP11 CCNA2 PRIM1 SHCBP1 RFC5 HK2 RAD51 FARSB ARHGAP11A ACP1 NUBPL SEPHS1 PAICS	up	***
GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_CYAN_UP	0.0001981	0.0034131	0.5188481	-0.6985218	-2.161147	16	USP12 CITED2 ADAM17 CSGALNACT2 CREBRF PSEN1 PTGER4 CDK17 PTP4A1 AKIRIN2 GNA13	down	**
MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN	0.0000068	0.0002000	0.6105269	0.5794596	2.161127	48	TRIP13 KIF20A HJURP CDC45 CENPF CDCA7 CDCA2 CDCA8 CDC6 TPX2 DTL MELK CEP55 AURKA KIF2C MCM7 KIF11 CDKN2C CENPH MIR3939 MNS1 KIF20B CENPK	up	***
GO_O_GLYCAN_PROCESSING	0.0000081	0.0002344	0.5933255	0.5752207	2.160066	49	MUC5B MUC13 C1GALT1 GALNT14 GALNT6 MUC4 GCNT3 MUC16 CHST4 MUC5AC GALNT4 GALNT10 MUC20 MUC6 GALNT9 XXYLT1 B3GNT3	up	***
GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP	0.0000000	0.0000003	0.7749390	-0.4147739	-2.159635	161	WEE1 EDNRB FIG4 SH2D3C PLEKHF2 TMOD3 CRY2 S1PR1 MEF2A ALAS1 FBXO3 IL1RN PILRA GGA2 CASP9 LTBP4 SEMA3B RAPGEF4 SERINC1 HSPB1 PRELP PAG1 NFE2L2 NDEL1 AKT3 PER3 TBX4 NPNT FMO2 FUT7 USP2 CLIC4 ATG7 PER2 CADM1 VIM AXL CD302 DUSP1 ARL4A AKIRIN1 SNX3 RYBP PSEN1 ARL6IP6 CYP2A6 HSPA1B DNAJA1 HOMER1 TAGLN2 SLC25A24 CACYBP PPP2CB MR1 LDLRAD4 NEK1 CEBPD ESYT1 METTL7A SNAP29 IL16 DNAJA2 CEND1 RAP1GAP SDHAF2 SLC25A38 PRKCH NDFIP1 DNAJB4 DNAJB1	down	***
GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_DN	0.0000000	0.0000001	0.7881868	-0.4101212	-2.159494	170	SLC31A2 EREG FCN1 HVCN1 KL EGR2 BACH1 INPP5A ARL8B TBC1D2 AGTPBP1 FUCA1 LAMP1 ARHGAP29 CD36 SPG21 B3GNT5 CARD16 SGMS2 ASAH1 HLX GPBAR1 TCF7L2 ARL11 EVI2B CFD TLE4 GCHFR CLIC4 CTSD UXS1 TLR4 EVI2A GCA CARS2 PINK1 LIN7A NCOA1 ZDHHC20 RBP7 FRY KIF13A NEK7 CPEB4 MAP4K4 TYROBP OGFRL1 ACSL1 RHOQ AZI2 CR1 ING3 DOK3 KIAA0232 SERPINB1 FPR2 GALC ATXN1 SOD2 TSPO NLRP3 UBE2D1 SCPEP1 PAK2 ITCH RHOT1 GRB10 TOX2 EVI5 DUSP6 CLIP1 KCNE1 ITGB1 PLXDC2 PPIP5K2	down	***
GSE45365_WT_VS_IFNAR_KO_CD11B_DC_MCMV_INFECTION_DN	0.0000000	0.0000007	0.7477397	0.4984567	2.158843	121	CEACAM1 TRIP13 FOXM1 KIF20A CYP19A1 CENPF FRK MND1 DEPDC1 NPY6R GINS1 E2F8 DAW1 ASPM OTOGL NUF2 CDCA8 PLD5 TPX2 CCNB2 BCL2L14 PRC1 TMEM132D DTL KHDC1 CLDN1 MELK HMMR CEP55 MKI67 TOP2A AURKA MYO10 REC8 SLC2A10 CDCA5 HELB CDC25C PAK1 CDK1 ENPP3 PSAT1 SPAG5 DLGAP5 ZNRF2P1 ARF5 TK1 GAS2 TSSK3 KDELR3 CDC20 UPK1B GADD45G BCL9 SHCBP1 ZNF462 MCU GNA14 CENPE UBE2C DCDC1 NLGN1 TK2 UMODL1 TMEM169 ESYT3	up	***
MODULE_320	0.0000066	0.0001966	0.6105269	0.7712329	2.158238	16	DDX11 NDC80 BRCA1 TTK PTTG1 ESPL1 NCAPD2 KIF23 KIF11	up	***
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP	0.0000000	0.0000001	0.8012156	-0.4061983	-2.157688	179	SIK1 HSD17B11 CRY2 INPP5A MTMR10 YPEL5 DYRK1A FRAT1 TMX4 CCNL1 TXNIP ANXA1 DPEP2 ATP2B1 UBL3 RGCC TMEM123 NDEL1 TMEM41B CLK1 TIPARP EVI2B MOAP1 KIAA0513 LEPROTL1 KLF11 MED6 KLF7 MGAT4A LAPTM5 PER1 DUSP1 ARL4A MAPRE2 BTG1 MYLIP KLRB1 SGK1 AQP3 HECA CD48 JUN PTGER4 PIK3R1 GPR183 ENTPD4 TSPYL1 TNFRSF10B FOS PELI1 KLF2 PTP4A1 FOSB TRAPPC10 IRS2 ZNF136 TOB1 KANSL2 RLF TPT1 CXCR4 EPHA4 SIK3 NLRP3 RBM48 DNAJB9 CYTH1 RORA DAZAP2 NR3C2 NUP160 PPP1CB ARHGEF18	down	***
JAATINEN_HEMATOPOIETIC_STEM_CELL_DN	0.0000000	0.0000000	0.8266573	-0.4005147	-2.156594	198	FCN1 CXCL16 ADTRP MNDA GPR65 MIR22HG TUBB1 SAMHD1 CITED2 GPCPD1 C5AR1 CLEC10A STX11 MAL TGFBR3 NCF2 IL1RN IGSF6 CD8A FGR TXNIP CD36 CD5 CLEC7A IFI30 RGCC SLC25A37 MPEG1 KLF4 CPVL THBS1 PLBD1 CCL3 DOCK9 COTL1 CCL4 LBH PRF1 FCER1G IL7R PIK3R5 CA1 HCK CD8B RBP7 KLRB1 SGK1 IL2RB RGS18 ANKRD9 AQP3 SLC14A1 KCTD12 ETS1 TYROBP CSTA CCR7 SELENBP1 LGALS2 CST7 KLF2 NKG7 CD1D CD86 LGALS3 DOK2 GABARAPL1 CCR1 TOB1 GPR18 IL18RAP LAT RTN1 CEBPD EPHA4 MEGF9 KLRK1 RORA GIMAP4 MAN1C1 LYZ KLRF1	down	***
BENPORATH_ES_1	0.0000000	0.0000000	0.9653278	0.4517615	2.156580	304	PTPRZ1 HELLS EGLN3 RUVBL1 PARPBP MCM10 GABRB3 SLC13A3 ELOVL6 CHEK2 BUB1B NUP107 PROM1 CCNB1 SOX2 IGF2BP3 PRIM2 TUBB2B DNMT3B AURKB PTTG1 ECT2 CDC6 RBBP8 MCM4 MCM2 LSR RAD54B CDC25A COCH GLDC ORC1 HPS3 MIS18A GINS4 CDT1 HMMR NUDT1 MAP7 CHAF1A IGF2BP2 BUB1 IDO1 PUS7 TMEM177 KIF2C MCM7 RRM2 TTLL12 CDCA5 WDHD1 PASK MCM3 PYCR2 AP1M2 SALL2 CD24 CHEK1 RAD51AP1 DSCC1 DBNDD1 PARP1 DCLK1 NCAPG2 CBX5 PAK1 DMKN CDK1 EPHA1 POLE2 CACHD1 DIDO1 BIRC5 ESRP1 GMNN NPM3 UNG DNA2 PDK1 FEN1 NLN MAD2L2 HAS3 ITPR3 MYO19 TRIM24 DLGAP5 PUS1 SNRPA MTA3 SALL4 L1TD1 GINS2 BCL2L12 EPB41L4B ETV4 PFAS CDC20 MAN2A1 HMGA1 KRT8 MCM6 MGME1 DNMT3A CYP2S1 MCM5 CAPRIN2 SRSF1 LRIG1 EXOSC5 GAD1 EPCAM KLHL7 MSH2 CCNA2 PRIM1 ZNF195	up	***
GO_ESTABLISHMENT_OF_ENDOTHELIAL_BARRIER	0.0001086	0.0020734	0.5384341	-0.5387553	-2.155875	38	SOX18 PECAM1 IL1B RDX RAPGEF2 CDH5 ENG MYADM PDE2A RAP1A PDE4D ROCK2 ROCK1 TJP1 CLDN5 ADD1	down	**
GO_CONDENSED_CHROMOSOME_OUTER_KINETOCHORE	0.0000104	0.0002858	0.5933255	0.8278907	2.154462	12	BUB1B CCNB1 CENPF NDC80 PLK1 SPDL1 BOD1 BUB1	up	***
LY_AGING_OLD_DN	0.0000041	0.0001301	0.6105269	0.5716789	2.154197	51	FOXM1 CCNB1 CENPF CDK4 KIF14 PLK1 CENPA MCM2 TYMS MYBL2 CCNF RANBP1 KIF23 ATR KIF2C KIF11 FBL PKMYT1 PARP1 CKS1B	up	***
GO_CHOLESTEROL_STORAGE	0.0001253	0.0023280	0.5188481	-0.6829403	-2.152372	17	PPARG LPL CD36 MIR146A STARD4 ABCG1 MSR1 EHD1 SOAT1 SREBF2	down	**
PUJANA_BRCA2_PCC_NETWORK	0.0000000	0.0000000	1.0376962	0.4414047	2.149426	387	DDX11 FOXM1 CDC45 FANCI ZNF273 TROAP CHEK2 BUB1B ZNF84 CCNB1 CENPF TIMELESS CPSF6 TTF2 CLGN NDC80 BRCA1 TTK GINS1 GTSE1 KIF14 GMPS POLE STIL AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 TFDP2 CCNB2 RBBP8 MCM4 PRKCA MCM2 TYMS MYBL2 CCNF LIG3 MAP2K6 SRPK1 NCAPD2 ZWINT CDT1 COX11 CASP2 MELK HMMR KIF23 CHAF1A MKI67 DCBLD2 HLTF PCCB KNTC1 BUB1 FANCA TOP2A AURKA CBX3 SYCP2 ATR POLD2 KIF2C MCM7 CD2AP MPHOSPH9 RRM2 PRKDC TRRAP WDHD1 RAD54L KIF11 MCM3 LMNB1 CDC25C LIG1 TOPBP1 CHEK1 DNAJC9 MAD2L1 NFYA RAD51AP1 MDM2 CAD BLM CNOT3 SKP2 CASP6 CDKN2C TMEM106C CDK1 POLE2 EXOSC2 FAT1 RBCK1 E2F1 UNG DNA2 FEN1 EZH2 NUP205 SPAG5 TTI1 CBX1 RNASEH2A DNMT1 ZNF354A FANCG TRIM24 CDC23 GNPAT DLGAP5 NINL SNRPA KIF22 SSRP1 DTYMK ANP32E KIF20B TMEM186 POLD1 CDC7 CKAP5 CPSF4 CDC20 RPA1 CLINT1 MCM6 TBCA MCM5 DPY19L2 DDX23 AATF LSM4 CHRNA5 TCERG1 PMS2P1 MSH2 CCNA2 SMARCA4 PRIM1 RFC5 WDR77 MRPL9 SRP9 PAXIP1 SNRNP200 ZNF131 SMC2 CENPE TCF3 PFDN4 SMPD4 SEPHS1 PAICS CDC25B UBE2C PNN TAF4 NELFA RAD1 DDB2 ZNF253 NUP93 TRAPPC6A NCAPH CYB5B CSTF1	up	***
GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN	0.0000000	0.0000001	0.7881868	0.4728003	2.148906	178	CDC45 BDH1 FANCI CCNB1 CENPF SORD BRCA1 PHGDH TTK GINS1 CDK4 AURKB PTTG1 GPI ESPL1 CDC6 TPX2 CCNB2 MCM4 MCM2 TYMS UMPS MYBL2 SHMT2 NCAPD2 NME1 RUVBL2 MELK EXO1 NUDT1 MKI67 AP4M1 KIF3B EEF1E1 CCT5 AURKA POLD2 RRM2 RGL1 WDHD1 RAD54L PKM KIF11 MCM3 CDC25C ABCB6 AHCY RAD51AP1 ALDOA THOP1 TMEM106C EXOSC2 FEN1 EZH2 MRPS12 LAPTM4B TUBG1 DLGAP5 FAH PSMA5 SAP30 PSMB3 CDC20 AHCYL1 STAMBP MRPL28 MCM5 SLC1A5 LSM4 NEFH CCNA2 SERPINI2 TPGS2 PFKM SMC2 PAICS UBE2C ENO1 PPP2R5D CALU CYB5B RNF14	up	***
REACTOME_DNA_DOUBLE_STRAND_BREAK_REPAIR	0.0000000	0.0000007	0.7477397	0.4967326	2.148232	120	EYA1 CHEK2 EYA2 TIMELESS POLQ BRCA1 POLE RBBP8 XRCC2 LIG3 EXO1 TP53BP1 POLM RHNO1 EME1 ATR POLD2 CLSPN PRKDC EME2 TOPBP1 CHEK1 RAD51AP1 XRCC1 BRIP1 BLM PPP5C PARP1 POLE2 DNA2 FEN1 DCLRE1C POLL RAD9A RAD51D POLD1 SLX4 RAD50 PALB2 RPA1 UBE2V2 KDM4B XRCC4 TDP1 UIMC1 CCNA2 RTEL1 RFC5 RAD51 EYA4 PAXIP1 SIRT6 TP53 RAD1 PIAS4 PARP2 MUS81 SPIDR TOP3A ATRIP RNF8 HERC2 RMI1 XRCC5 TIPIN PPP4C POLD3 XRCC6 RMI2 RAD51B RFC3 BARD1 POLE4 RFC4	up	***
GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN	0.0000000	0.0000001	0.7881868	-0.4046317	-2.145962	182	CXCL3 SLC31A2 IL1A SWAP70 OLR1 ZC3H12C IL1B CCRL2 CDC42EP2 STX11 SEMA6D SLC44A2 ADAM17 ITGA5 SERPINB9 NR4A1 ZEB1 CSRNP1 STAT5A PTGIR CCL22 SPNS3 MEFV VASP NFKB1 IRAK2 CCL4 CCSER2 DUSP1 N4BP1 MAFF MOB3A RASGEF1B SNN HCK PKIG CHDH SOCS3 MTMR14 JUNB RCAN1 PPP1R15A PTGER4 CCR7 SKIL CD83 PSTPIP2 REL NOL7 DENND4A EHD1 FPR2 DUSP5 CD86 PIM1 GPR84 SOD2 TAGAP PLEKHO2 PDE4B ETS2 GEM ICAM1 NLRP3 TRAF1 NFKBIA TNFSF9 SAMSN1 MIER3 DNAJA2 SPATA13 FNBP1 HERPUD1 EGR1 CLEC4E ZFP36 CD69 HLA-DRB1 IRF1 B3GALNT2 FCHSD2 NR4A3 CFLAR PTGS2 JARID2 NFKBIZ DUSP2 RNF19B	down	***
VANHARANTA_UTERINE_FIBROID_DN	0.0000056	0.0001713	0.6105269	-0.4862455	-2.144774	59	GATA2 PHYHIP SOX17 RTN3 CITED2 NR3C1 GIMAP6 TRIB1 IER2 KLF4 ATF3 PTGER3 SMAD7 WFS1 MAFF ACKR3 KLF2 HIVEP2 GSAP PDLIM1 LTBP1 GSTM5 TFPI MS4A4A PTCH1 DAPK1 ABCA8 CBX7 EGR1 NR4A2	down	***
GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_DN	0.0000000	0.0000002	0.7881868	0.4792289	2.143837	157	FOXM1 HJURP TROAP XYLB PLEKHA5 MUC16 DEPDC1 BRCA1 GTSE1 DBF4B TRAIP DNMT3B PTTG1 E2F3 CCNB2 TYMS MYBL2 CCNF PLS1 SPPL2B HAUS5 WDR62 MELK EXO1 CLSPN RRM2 GCAT RAD54L ORC6 CC2D1A LRRC61 PKMYT1 PTGDR2 FADS2 TST NAA40 SLC25A10 HSPBP1 CDKN2C FASTK NUSAP1 ETV7 ASF1B CDK1 TNFRSF21 ATP2A1 E2F1 RECQL4 STK11 ZNF500 GSS PTGES2 TK1 PINLYP ATAD5 EPN1 KLHL23 CENPM AAAS TTLL3 CDK5RAP2 MRPL28 KPTN SLC1A5 NEFH SPON2 CEP85 MICAL3 RTEL1 DOHH CEP164 CAPN10 RHOT2 MXD3	up	***
GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP	0.0000000	0.0000001	0.7881868	-0.4045465	-2.143276	173	PAN3-AS1 OTUD1 CD44 BACH1 CIR1 YPEL5 NCF2 TET2 FRAT1 ZEB2 ATP2B1 ASAP1 UBL3 SERINC1 PICALM LITAF RGCC AKT3 ZFYVE16 SRGN TCF7L2 LINC00528 ZSWIM6 TCP11L2 PLAUR DAB2 THBS1 SOCS5 SCAF4 PDE3B PNRC1 CLK4 UBE2B DUSP1 IL7R PI4K2A BTG1 MED28 RABGAP1 IFNGR1 CSTA SKIL PNPLA8 DDX5 HOMER1 OGFRL1 TSPYL1 ZNF350 FOXO3 TGIF1 FAM228B BAZ2B MAP3K2 HBP1 APLP2 KYNU N4BP2L2 RGS2 CSNK2A2 CXCR4 EPHA4 NLRP3 PAIP2 THEMIS2 LYZ ARRDC2 CBX7 TMEM43 ZNF106 AOAH RB1CC1 ZFYVE1 ZFP36 SLC26A11 MTSS1 SNRPN RAB11FIP2 SIRT1 DUSP22 NR4A3 CFLAR MAT2B	down	***
VERHAAK_AML_WITH_NPM1_MUTATED_UP	0.0000000	0.0000004	0.7614608	-0.4145768	-2.143097	150	CXCL3 EREG HMOX1 FCN1 IL1B FBP1 SNX10 CAT AQP9 C5AR1 SLC15A3 BCL2A1 EPB41L3 TRIB1 PILRA LILRB3 FGR CD36 DPEP2 MCTP1 LMNA IFI30 PBX3 PTX3 CASP1 PTAFR PLAUR CPVL THBS1 ABCC4 CTSD CCL3 CXCL2 CCL4 TLR4 CD300C PLEK HCK NINJ1 TRGC2 HCAR3 ADCY2 IL6 C1QA HK3 TREM1 LGALS2 ACSL1 PELI1 SORT1 CD86 SOD2 MEIS1 CCR1 LTBP1 ETS2 CCL20	down	***
chr13q34	0.0000382	0.0008639	0.5573322	-0.5294106	-2.142971	39	GAS6 LAMP1 COL4A2-AS2 ATP11A-AS1 ANKRD10 TMEM255B ANKRD10-IT1 RNU1-16P CARS2 LINC00346 CUL4A ATP11A TEX29 GAS6-AS1 TUBGCP3 IRS2 CDC16 DCUN1D2-AS DCUN1D2 ING1 COL4A2-AS1 PCID2 COL4A2	down	***
GO_BLOOD_VESSEL_MATURATION	0.0001464	0.0026469	0.5188481	-0.8555088	-2.142330	8	ACVRL1 CDH5 LYL1 S1PR1 RECK	down	**
GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_UP	0.0000000	0.0000004	0.7614608	-0.4113915	-2.142024	161	EREG FCN1 OLR1 LTA4H CYP27A1 FYN CD44 BACH1 AQP9 FLVCR2 NCF2 CD9 RFTN1 CD5 PBOV1 BTG2 EIF5 ANPEP SLC7A11 LCP1 AKT3 PTGIR CCL22 NFKB1 PDE3B ATF3 PNRC1 ARAP3 DUSP1 HLA-DQA1 CRIM1 VWF HCK UTRN DDX17 JUNB CCR7 GLIPR1 CD83 GPR183 IDS PTGER2 CGGBP1 CST7 GRIK1 PPM1F MOB1A FOXO3 NAB1 GNG5 SOD2 KYNU PDE4B PHLPP2 TPT1 CXCR4 ITGAE TRAF1 SRSF10 NFKBIA DNAJB5 LYZ ZBTB44 AFTPH CSF2RB C5AR2 TMEM43 CLEC4E GNG11 LAMP3 HLA-DRB1 DDX21 IRF1 STARD5 CFLAR IRF4 MSC DUSP2 SLAMF7 IL10RA CYTIP TANK	down	***
REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS	0.0000142	0.0003782	0.5933255	0.6170320	2.141539	36	CDC45 MCM10 CDC6 MCM4 MCM2 CDC25A ORC1 MCM8 ATR MCM7 CLSPN MCM3 CDC25C CHEK1 ORC6 RAD9A CDC7 RPA1 MCM6 MCM5	up	***
EGUCHI_CELL_CYCLE_RB1_TARGETS	0.0000062	0.0001857	0.6105269	0.7090968	2.141509	22	KIF20A NEK2 NDC80 CDCA8 ECT2 MCM4 MCM2 BUB1 MCM7 KIF11 MCM3 CDC25C FEN1 MCM6 MCM5 CCNA2 SMC2 CENPE	up	***
GO_MITOTIC_G2_M_TRANSITION_CHECKPOINT	0.0000105	0.0002890	0.5933255	0.6830093	2.141245	25	HMGA2 TICRR BRCA1 BRSK1 CDC6 ORC1 CDK5RAP3 CLSPN TOPBP1 BLM CDK1	up	***
GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP	0.0000000	0.0000001	0.7881868	-0.3989492	-2.140702	188	SIDT2 HMOX1 SWAP70 SOWAHC LPXN PPP4R1 GFOD1 YPEL5 SYS1 GGA2 EDEM1 ATP2B1 B3GNT5 ZBTB21 SLAIN2 NR4A1 NFE2L2 PPP1R13B ZEB1 BTG3 GMEB1 MAP2K3 ROCK2 CSRNP1 DUSP3 BIRC2 PXDC1 MAP1LC3B FBXL3 RBMS1 UBE2B CCSER2 DUSP1 PIK3C2A PLEK GNAQ PAFAH1B1 ANXA3 CD300LB VWF FOXN3 RYBP GABPA UHRF2 ATXN1L IFRD1 PNPLA8 MPZL3 CD83 HSPA13 PCGF5 RNF24 RHOQ CDK17 AZI2 ITGA9 RELL1 ATP6V0C MEIS1 WBP2 JUND C3orf38 IL18RAP LAT ITPRIPL2 ZNF438 MEX3C EPHA2 KPNA4 MAFK ARPC5 TLK2 PAIP2 NABP1 FCRL1 PUS3 TBPL1 TMEM43	down	***
TAVOR_CEBPA_TARGETS_UP	0.0000204	0.0005103	0.5756103	-0.5091390	-2.140586	49	HMOX1 FIG4 BCL2A1 IL1RN TRIB1 ANXA1 BTG2 LITAF PTX3 KIAA0513 PTPRC KCNMB1 ID2 ARC CCND2 BTG1 SERTAD2 TRGC2 HCAR3 RAB31 GLIPR1 CD7 ACSL1 SOD2 RGS2 CXCR4	down	***
chr13q14	0.0000010	0.0000373	0.6435518	-0.4249074	-2.139539	112	MED4-AS1 THSD1 MED4 RLIMP1 SLC25A30 RN7SL413P WBP4 PCNPP5 FAM124A SERP2 PPP1R26P1 LCP1 RB1 RGCC RNU2-6P ARL11 CDADC1 FOXO1 ITM2B SPRYD7 KPNA3 LACC1 ELF1 ESD LRCH1 SUGT1P3 NUDT15 DLEU2 RGS17P1 RAD17P2 NAA16 OGFOD1P1 TSC22D1 LINC00562 PHF11 RNU6-60P INTS6 SNORA31 SETDB2 TPT1 DHRS12 NEK3 GTF2F2 LPAR6 RPL18P10 GPALPP1 SUGT1 RN7SL288P LRRC63 RNU6-57P VPS36 TRIM13 RCBTB2 FNDC3A MRPS31P5 WDFY2 MIR621 RNY3P2	down	***
GO_REGULATION_OF_MACROPHAGE_ACTIVATION	0.0000918	0.0018004	0.5384341	-0.5152345	-2.138906	45	PLA2G10 IL1RL1 GRN SLC7A2 IL10 THBS1 CEBPA CCL3 PTPRC TLR4 IL6 CST7 CD74 SYT11 HAVCR2 CTSC RORA LDLR SPHK1 TREM2 WNT5A SHPK PJA2 MFHAS1	down	**
UZONYI_RESPONSE_TO_LEUKOTRIENE_AND_THROMBIN	0.0000310	0.0007244	0.5573322	-0.5681678	-2.137967	34	BMP2 SIK1 CITED2 NEDD9 HBEGF MAP3K8 HLX NR4A1 MCL1 KLF4 CXCL2 ATF3 DUSP1 PDK4 CREM RCAN1 KLF2 RGS2 GEM EGR1 NR4A2 ZFP36 NR4A3 PTGS2	down	***
GO_NUCLEAR_CHROMOSOME_SEGREGATION	0.0000000	0.0000000	0.8266573	0.4599092	2.136524	209	TRIP13 DDX11 SPICE1 DDX12P STAG3L2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ECT2 ESPL1 CDC6 PRC1 NCAPD2 ZWINT CDT1 SPDL1 KIF23 STAG3 BOD1 BUB1 TOP2A MAP10 EME1 REC8 SYCP2 TPR KIF2C MAD1L1 CDCA5 FANCD2 HORMAD1 EME2 MAD2L1 DSCC1 BRIP1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 SUN1 DIS3L2 NCAPG FEN1 SPAG5 TRAPPC12 MAD2L2 KLHL22 KPNB1 CCNE1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA CENPQ AKAP8L ESCO2 ANAPC1 SLX4 ANKRD31 CENPK STAG3L4 MEI1 CDC20 TUBG2 CHMP4C FANCM CDK5RAP2 CHTF8	up	***
GO_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0000088	0.0002525	0.5933255	-0.4974670	-2.135795	55	HMOX1 ADTRP GATA2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 CLEC14A NR4A1 AKT3 FOXC2 KLF4 THBS1 PIK3C2A SRF NOTCH1 RHOJ MIR23A MIA3 FGF2 STARD13 GREM1 ITGB1 MIR2355 EFNB2	down	***
GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_DN	0.0000000	0.0000003	0.7614608	-0.4066715	-2.134329	167	CXCL3 IL1A USP12 ZC3H12C RAPGEF2 INSIG1 CCRL2 STX11 FAM49A ADA BTG2 MAP3K8 RNF144B TTYH2 ZNF697 BTG3 TCF7L2 CSRNP1 PLAUR PXDC1 DRAM1 KLF7 NFKB1 CDKN1A CXCL2 ATF3 ZBTB43 DUSP1 TP53BP2 SRF BTG1 HCAR3 IL6 SAR1A SOCS3 PLEKHA3 OASL ETV3 ARL5B STAT4 PLK3 JUNB PPP1R15A PTGER4 CCR7 IRF8 LYRM1 GPR183 FSD1L REL ACSL1 PELI1 FXYD6 EHD1 DUSP5 LRRC32 KCNA3 GEM ICAM1 ARAP2 IL18RAP TNFAIP8 MIR155HG RIPK2 NUP98 TRAF1 NFKBIA EDN1 LDLR NABP1 PIM3 NR4A2 DCUN1D3 HES4 DNAJB4 MT1E LAMP3 DAPP1 IRF1 NR4A3 CFLAR PTGS2 HIVEP1 NFKBIZ DUSP2 C15orf48 SLAMF7 RASSF5 IL10RA C2orf15 SLAMF1	down	***
TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_DN	0.0001324	0.0024429	0.5188481	-0.5647078	-2.134171	32	HHEX LYL1 TGFBR2 MS4A1 CD37 NFKB1 MAPRE2 RHOG IFNGR1 CD83 IRF8 REL MOB1A SERPINB1 GPR18 MMD CCND3	down	**
GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000000	0.0000002	0.7749390	-0.4010921	-2.133237	184	SLC31A2 KMO SLC47A1 PECAM1 PPARG FBP1 DCSTAMP MIR22HG FCER1A FOSL1 PCOLCE2 C5AR1 SLC15A3 TBC1D2 CD1C CD9 FUCA1 WBP4 LAMP1 AGPAT4 IGSF6 FGR NUMB CD36 CD33 ABCG2 ANPEP ABHD6 GRN SPRY2 PDGFA CASP5 FABP5 CFD BST1 STX3 ATP6V1D TPP1 CTSD CDKN1A TM6SF1 MATK PRCP TMEM9B FLT1 CYB5R1 RAB31 HK3 CTSZ ATP6V0B CD83 IRF8 RALB PLCG2 ATP6V0D1 SORT1 FXYD6 MCUR1 CPT2 KYNU	down	***
GO_DNA_PACKAGING	0.0000002	0.0000091	0.6901325	0.5019710	2.132649	104	HMGA2 HELLS HJURP RUVBL1 CCNB1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A SRPK1 NCAPD2 CHAF1A TOP2A CENPL GPER1 TPR CENPW CDCA5 CHAF1B CENPO NCAPG2 NUSAP1 ASF1B CDK1 CENPH NCAPG CENPP HIRA CENPQ AKAP8L NOC2L CHD5 CENPK CENPV CENPM HMGA1 CENPT BANF1 CHMP1A SIRT6 SMC2 TP53 NCAPD3 SART3 NCAPH ACIN1 DFFB SMYD3 NPM1 RNF8	up	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_UP	0.0000000	0.0000008	0.7477397	-0.4101730	-2.130546	160	IL1A DENND5A USP12 SOWAHC IL1B NR3C1 NEDD9 BCL2A1 AGPAT4 SCARF1 RFTN1 LRRFIP2 HBEGF HECW2 MTF1 TNIP3 RNF144B SLC25A37 AKT3 PTPN12 TBC1D9 PLAUR PRKD3 TNFSF15 MAP1LC3B DENND3 SOCS2 CLIC4 NFKB1 CXCL2 CCL4 DNTTIP2 PROCR KANK1 IL6 PGD SOCS3 SH3BP5 HRH1 TREM1 CSTA WTAP ELOVL7 OSM FSD1L TNFRSF9 ACSL1 MAPK8 SAV1 EHD1 GSAP FPR2 SOD2 PDE4B ETS2 CCL20 MIR155HG NBN IER5 CDC42EP3 DIXDC1 PLGRKT MAP3K4 BCAT1 NFKBIA RASSF8 TMCC3 PURB TRIM36 RABGEF1 MZT1 DCUN1D3 OSGIN2 MSANTD3 YRDC HEY1	down	***
GO_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	0.0000017	0.0000593	0.6435518	-0.4494925	-2.129250	83	ACVRL1 TEK ACE DLC1 IL1B WNT4 RAPGEF2 CAV1 CORO1C RHOA APOD RAP1A SFRP1 GPBAR1 ROCK2 SNAI1 DUSP3 LIMS1 ROCK1 TJP1 THBS1 CLDN5 PEAK1 MYO1C FAM107A MAP4K4 RAPGEF1 PRKACA PPM1F EPHA3 CLASP2 MACF1 EPB41L5 EPHA2 LIMCH1 PTEN IQGAP1	down	***
GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP	0.0000000	0.0000005	0.7614608	-0.4064033	-2.129051	157	USP12 LRRC8C MMRN1 SRSF7 INPP5A USP47 PDCL DNAJB14 ASAP1 MAP3K8 ZBTB21 ZNF410 ADIPOR1 ZEB1 SRGN BTG3 SDCBP DENND6A THBS1 MED6 SPAG9 PAFAH1B1 TP53BP2 USP16 FAM76B RABGGTB NINJ1 TECTA AREG DNAJC27 SGK1 SOCS3 SEC14L1 ARL5B MITF SH3BP5 CPEB4 SHOC2 IFNGR1 ELOVL7 PNPLA8 GPR183 KBTBD8 FSD1L REL UVRAG DLEU2 AGFG1 GPRIN3 CLUHP3 PELI1 PSMD12 VAV3 AP1G1 CCNH GEM INTS6 RAB5A ARIH1 TXNDC11 SSH2 OSER1 JMJD1C DNAJB9 MMD ZNF165 EHD4 PIM3 MB21D2 ICOS KMT2E C6orf62 PIAS2	down	***
GSE2706_UNSTIM_VS_2H_R848_DC_DN	0.0000000	0.0000004	0.7614608	-0.4063773	-2.128912	163	CXCL3 IL1A USP12 GREB1 ZC3H12C IL1B RAPGEF2 MIR22HG INSIG1 CCRL2 STX11 CLCF1 SGMS2 BTG2 MAP3K8 RNF144B TTYH2 ZNF697 SERPINB9 BTG3 MAP2K3 CSRNP1 PLAUR PXDC1 TNFSF15 DRAM1 DENND3 NFKB1 CXCL2 IRAK2 CCL4 ZBTB43 PLEK INHBA PIK3R5 TP53BP2 MAFF BTG1 NINJ1 SLC25A25 IL6 SOCS3 ARL5B STAT4 CELF1 PLK3 PPP1R15A PTGER4 IRF8 LYRM1 FSD1L REL ACSL1 FXYD6 EHD1 DUSP5 LRRC32 STK40 GEM ICAM1 TNFAIP8 MIR155HG TRAF1 NFKBIA EDN1 MCOLN2 NABP1 PMAIP1 PIM3	down	***
REACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TN_POLYAGGLUTINATION_SYNDROME_TNPS	0.0000159	0.0004142	0.5756103	0.8174172	2.127207	12	MUC5B MUC13 C1GALT1 MUC4 MUC16 MUC5AC MUC20 MUC6	up	***
GO_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0001418	0.0025746	0.5188481	-0.5204298	-2.126909	40	HMOX1 GATA2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 AKT3 FOXC2 KLF4 THBS1 PIK3C2A NOTCH1 RHOJ	down	**
GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR	0.0000045	0.0001422	0.6105269	0.5528531	2.126009	57	HMGA2 DDX11 FOXM1 PARPBP TIMELESS POLQ WDR70 FIGNL1 MAGEF1 TP53BP1 AUNIP PRKDC HELB CHEK1 RAD51AP1 PML RECQL5 PARP1 MAD2L2 MGMT NUDT16 PARP9 UBQLN4 TWIST1 DTX3L RTEL1 RAD51 NUDT16L1 SIRT6	up	***
ROSS_AML_WITH_CBFB_MYH11_FUSION	0.0000549	0.0011683	0.5573322	-0.5048307	-2.123595	46	CD52 CLEC10A MEF2A CD1C PTPRM SLC7A7 CLEC7A PLBD1 MYH11 CTSS KCTD12 MN1 LGALS2 TNFSF13 KIF17 CEBPD MEGF9 CD1E ANXA11 GIMAP4 DUSP6 S100A8 TES	down	**
GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP	0.0000000	0.0000002	0.7749390	-0.3986979	-2.121929	177	CD52 SIK1 HSD17B11 SAMHD1 CITED2 CRY2 YPEL5 MSRA DYRK1A ANAPC15 FRAT1 TMX4 CCNL1 TXNIP ANXA1 PPP3CA CLK1 PDE4D EVI2B MOAP1 ITM2B LEPROTL1 MED6 MGAT4A NPAS3 PER1 ALOX5AP CCDC59 EVI2A ARL4A MAPRE2 ARHGDIB BTG1 KLRB1 PIKFYVE AQP3 HECA CD48 JUN JUNB PIK3R1 MBNL2 ENTPD4 UVRAG TSPYL1 SNRK FOS KLF2 PTP4A1 YTHDF3 MYL12A TSPAN14 IRS2 HBP1 TOB1 KANSL2 CLEC2B HAUS3 BNIP3L SLC35D2 RLF EPHA4 S100A4 ICAM3 NR3C2 NUP160 CNN2 PPP1CB ARHGEF18 NR4A2 RB1CC1 FAM8A1 FAM53B CD69 DNAJB1 PIAS2	down	***
GO_TRANSFORMING_GROWTH_FACTOR_BETA_ACTIVATED_RECEPTOR_ACTIVITY	0.0002135	0.0036231	0.5188481	-0.7978916	-2.121249	10	ACVRL1 BMPR2 TGFBR3 TGFBR2 LTBP4	down	**
MODULE_403	0.0000067	0.0001966	0.6105269	0.5879468	2.120865	42	CDC45 NEK2 CCNB1 CDK4 PLK1 CENPA MYBL2 MELK MKI67 TOP2A ATR MCM3 TOPBP1 CDK1 E2F1 UNG FEN1 RECQL4 TK1 DTYMK CDC20 FTCD RPA1 UBE2V2 MCM6 SNX11 MSH2 CHD3 TRUB1 CDC25B	up	***
WHITFIELD_CELL_CYCLE_S	0.0000000	0.0000019	0.7195128	0.4821687	2.119732	131	ANKRD18A ANKRD36C ABCC2 HELLS CDC45 UBE2T PRIM2 BRCA1 E2F8 CCDC14 AC011043.1 COL7A1 RBBP8 TYMS TMCC1 MCM8 ZWINT TRIM45 HAUS5 CASP2 CCDC150 EXO1 FANCA TOP2A ABCC5 RRM2 CDCA5 RHOBTB3 RAD54L RAD51AP1 DSCC1 CAPS PKMYT1 BRIP1 RAD18 BLM COQ9 ASF1B GOLGA8A DNA2 FEN1 EZH2 INTS7 MBD4 CENPQ ESCO2 CDC7 GOLGA6L4 KLHL23 CENPM EFHC1	up	***
LENAOUR_DENDRITIC_CELL_MATURATION_DN	0.0000003	0.0000126	0.6749629	-0.4241511	-2.119459	107	CXCL3 FCN1 OLR1 IL1B LTA4H FBP1 CD44 C5AR1 SLC11A1 TXNIP BTG2 ANPEP CES1 CD37 BST1 PTAFR PLAUR CXCL2 FCER1G ELK3 EVI2A ARHGDIB NINJ1 EMP3 PSEN1 IDS CXCL5 LGALS2 TSC22D1 NFYC SOD2 KYNU ADAM10 CLEC2B RTN1 S100A4 SREBF2 BCAT1 NFKBIA LYZ DUSP6 LHFPL2 ITGAL NCF1 S100A8	down	***
GO_DOUBLE_STRAND_BREAK_REPAIR	0.0000000	0.0000000	0.8140358	0.4610325	2.119250	191	HMGA2 TRIP13 DDX11 FOXM1 EYA1 CDC45 PARPBP CHEK2 TIMELESS POLQ BRCA1 NABP2 WDR70 FIGNL1 RBBP8 MCM4 MCM2 RAD54B XRCC2 CIB1 MCM8 LIG3 GINS4 MAGEF1 TP53BP1 POLM AUNIP EME1 REC8 MCM7 MMS22L CDCA5 PRKDC HELB RAD54L MCM3 EME2 CHEK1 RAD51AP1 XRCC1 BRIP1 BLM PML RECQL5 PARP1 POLN RFWD3 DNA2 AP5Z1 FEN1 MAD2L2 RECQL4 DCLRE1C POLL RAD51D ESCO2 MGMT GINS2 NUDT16 POLB PARP9 SLX4 CDC7 RAD50 UBQLN4 PALB2 TWIST1 RPA1 UBE2V2 MCM6 XRCC4 MCM5 TDP1 UIMC1 MSH2 DTX3L RTEL1 RAD51 TNKS1BP1 PAXIP1 NUDT16L1 SIRT6 TONSL SWI5 TP53	up	***
GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000000	0.0000001	0.8012156	0.4687959	2.118953	170	KIF20A MCM10 FANCI BUB1B IGF2BP3 TIMELESS UBE2T MPP6 CPSF6 KIF18B NDC80 PRIM2 GINS1 POLE STIL AURKB CENPA PTTG1 ECT2 RBBP8 XPNPEP1 NUDT1 CISD1 CEP55 SMAGP KNTC1 TOP2A CENPL MCM7 CENPW MMS22L FANCD2 MCM3 PFN2 LIG1 ORC6 MAD2L1 CKAP2L RAD51AP1 XRCC1 WNT5B NCAPG2 CDKN2C NUSAP1 ASF1B GMNN POLR3K NCAPG DNA2 CENPP TSNAXIP1 SNRPA HMGN3 ESCO2 GINS2 ASNS ATAD5 DNASE1 CENPK LIMA1 ASRGL1 ZRANB3 GINS3 HMCES GNAL PRR11 SNRPD2 BLVRB ZWILCH ARHGAP11A MXD3 VDAC3 SLC12A2 SMC2 PGPEP1 TMEM256	up	***
GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_UP	0.0000000	0.0000004	0.7614608	-0.4037282	-2.118882	167	SC5D DENND5A GPR65 OTUD1 ARIH2OS YPEL5 AGTPBP1 HEG1 IER2 PDE2A ZBTB4 DPEP2 CNST PTPRM ASAH1 CLEC7A RNF125 PPP3CA SPTBN1 PDE4D TCF7L2 PPP3CC ITPRIP AHNAK PSTK KLF4 COQ10B KLF11 ST7L NR1D2 C9orf72 DUSP1 PLEK UBASH3B MAFF PKIG MYLIP SOCS3 UTRN AQP3 HCST SNX29 MAP4K4 ATXN1L SKIL PNPLA8 MBNL2 GPR183 FOS PTP4A1 BIN2 NAP1L5 FAM204A FAM228B TSC22D1 ZNF844 IRS2 PIM1 KCNA3 GABARAPL1 TOB1 HELZ EPHA4 TTC32 CD3G DNAJB9 ITCH ZFAND2A CFL2 MDS2 NR4A2 FAM8A1 DRAM2 ASH1L-AS1 MICAL1	down	***
MODULE_410	0.0002296	0.0038650	0.5188481	-0.5775181	-2.118304	28	FCN1 OLR1 ASGR1 CLEC3B THBD CHIT1 CLEC10A CD22 SELL SELP SFTPD GFPT2 LGALS2 LGALS3 CLEC2B	down	**
BROCKE_APOPTOSIS_REVERSED_BY_IL6	0.0000000	0.0000012	0.7337620	-0.4197045	-2.117960	135	SIK1 CD44 ST3GAL6 GAS6 HEG1 IER2 HBEGF RAPGEF4 EIF5 MAP3K8 LITAF CAV2 EIF4E RB1 HNRNPU MCL1 EPB41L2 EVI2B DUSP3 ID3 STK17B ID2 PLEKHB2 EVI2A ADIPOR2 SH2D2A MAFF HCK CD8B PHTF2 SGK1 PNO1 SOCS3 JUN JUNB IFNGR1 HSPA13 GRB2 CDK17 PTP4A1 FOXO3 MSMO1 TGIF1 DPM1 DUSP5 ZBTB11 PIM1 GNA13 LTBP1 ICAM1 SF1 CXCR4 TMEM184B DAPK1 DNAJB9 LDLR RNF13 ARFGAP3 DNAJA2	down	***
REACTOME_HOMOLOGY_DIRECTED_REPAIR	0.0000002	0.0000099	0.6901325	0.5037167	2.117614	94	TIMELESS POLQ BRCA1 POLE RBBP8 XRCC2 LIG3 EXO1 TP53BP1 RHNO1 EME1 ATR POLD2 CLSPN EME2 TOPBP1 CHEK1 RAD51AP1 XRCC1 BRIP1 BLM PARP1 POLE2 DNA2 FEN1 RAD9A RAD51D POLD1 SLX4 RAD50 PALB2 RPA1 UBE2V2 UIMC1 CCNA2 RTEL1 RFC5 RAD51 SIRT6 RAD1 PIAS4 PARP2 MUS81 SPIDR TOP3A ATRIP RNF8 HERC2 RMI1 TIPIN PPP4C POLD3 RMI2 RAD51B RFC3 BARD1 POLE4 RFC4	up	***
GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS	0.0007320	0.0099557	0.4772708	-0.6940495	-2.117173	15	SPN TNFRSF8 CLEC7A HSPB1 THBS1 TLR4 PSEN1 TYROBP	down	**
GO_CELL_CYCLE_CHECKPOINT	0.0000000	0.0000000	0.8140358	0.4586414	2.117026	198	HMGA2 TRIP13 CDC45 TICRR CHEK2 BUB1B CCNB1 CENPF TIMELESS NDC80 BRCA1 TTK BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB CDC6 TFDP2 ORC1 DTL ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 TP53BP1 KNTC1 RHNO1 BUB1 TOP2A AURKA EME1 ATR TPR MAD1L1 CLSPN PRKDC NSUN2 HORMAD1 CDC25C SOX4 EME2 TOPBP1 CHEK1 NEK11 MAD2L1 SOX11 MDM2 BRIP1 BLM PML CNOT3 CDK1 RFWD3 E2F1 DNA2 CNOT11 MAD2L2 KLHL22 CEP63 INTS7 CNOT2 RAD9A FBXO4 FZR1 PROX1 CDC20 BCL2L1 CHMP4C CDK5RAP2 THOC5 PRMT1 UIMC1	up	***
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP	0.0000000	0.0000001	0.8012156	0.4693064	2.116637	169	CCL19 KIF20A FANCI AP3B2 BUB1B CCNB1 TTK RACGAP1 E2F8 CDCA8 AURKB PTTG1 AKR1C1 ESPL1 TPX2 CCNB2 MCM2 TYMS COCH DTL ZWINT AGK MELK NDUFB8 HMMR KIF23 MKI67 CUL9 EMC9 KIF15 IGLV1-44 KIF2C ABCC5 RRM2 RGL1 RBM28 KIF11 CHEK1 FBL RAD51AP1 AKT2 WNT5B IDH2 MNAT1 NUSAP1 TMEM106C CBX5 CDK1 POLE2 BIRC5 NCAPG SLC25A13 FEN1 SPAG5 SNRNP25 DLGAP5 UROS TK1 DTYMK GINS2 GALNT3 CDC20 MCM6 TDP1 LANCL2 RHOBTB1 STK39 NEDD8 CCNA2 SLC2A5 STAB1 TTC31 CAPN10 SEC13 AGBL5 UQCRQ OSGEP BCAS3 CDC25B UBE2C MZF1 C12orf10 CCL13 PARP2	up	***
SHEPARD_BMYB_TARGETS	0.0000055	0.0001685	0.6105269	0.5503164	2.116254	57	FOXM1 PARPBP CCNB1 TOX3 TTK CDCA2 GTSE1 KIF14 ANLN ASPM AURKB TPX2 GOLGB1 PRC1 MELK KIF23 MKI67 KIF11 MDK SOX11 CDK1 BIRC5 DLGAP5 TACC3 TK1 CDC20 HMGA1 CKAP2 RTKN PRR11 BMS1	up	***
GO_REGULATION_OF_PHAGOCYTOSIS	0.0000147	0.0003883	0.5933255	-0.4550573	-2.114675	77	SIRPB1 CD300LF PPARG GATA2 IL1B GAS6 SLC11A1 FGR CD36 RAP1A CLEC7A PTX3 SIRPA PTPRC SFTPD FCER1G LYAR C4BPB HCK NCKAP1L SNX3 IL2RB APPL1 RAB31 RAPGEF1 ATG3 PRKCG FPR2 SYT11 PTEN ANO6 SPHK1 CYBA TREM2 CALR HMGB1	down	***
KAUFFMANN_DNA_REPAIR_GENES	0.0000000	0.0000000	0.8390889	0.4567527	2.113785	204	TP63 CHEK2 POLQ BRCA1 PMS2P5 POLE PTTG1 RBBP8 RAD54B PMS2 XRCC2 CIB1 LIG3 SMUG1 TOP3B RUVBL2 EXO1 NUDT1 CHAF1A TP53BP1 POLM FANCA TOP2A EME1 PMS2P4 POLA2 ATR POLD2 MAD1L1 RRM2 PRKDC RAD54L FANCD2 CHAF1B LIG1 TOPBP1 CHEK1 MAD2L1 RAD51AP1 XRCC1 BRIP1 RAD18 BLM ERCC2 MNAT1 RECQL5 PARP1 POLN POLE2 UNG NEIL3 FEN1 MAD2L2 RECQL4 TEP1 FANCG DCLRE1C FANCF MTOR POLL MBD4 RAD9A RAD51D SSRP1 MGMT POLD1 POLB RAD50 SUPT16H RPA1 FANCM UBE2V2 WRNIP1 XRCC4 TDP1 GADD45G PMS2P1 MSH4 PMS1 MSH2 RFC5 RAD51 SMC2 PNKP XPC MPG TP53 NEIL1 APEX1 RAD1 DDB2 ERCC3 ALKBH2 PARP2 MUS81 MLH3 TOP3A	up	***
MODULE_451	0.0000188	0.0004771	0.5756103	0.6508171	2.113756	28	CDC45 NEK2 CCNB1 MKS1 CDK4 PLK1 CENPA MYBL2 MELK MKI67 TOP2A RNFT2 TOPBP1 CDK1 ESRP1 SPATA9 FEN1	up	***
GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_UP	0.0000000	0.0000003	0.7749390	-0.3989612	-2.113685	173	EPAS1 PECAM1 PTPRE TUBB1 CCRL2 GFOD1 CBL TGFBR2 PDE2A PLA2G7 ABCG2 HLX ADIPOR1 TMEM123 AKT3 FLI1 SDCBP TCP11L2 ITM2B ROCK1 ZFAND5 STK17B THBS1 LAPTM5 PDE3B PTPRC SELL HPSE LBH ELMSAN1 ARL4A CPT1A KLRD1 ARHGDIB HEXB MYLIP CREBRF SLCO2B1 HCST HECA MSRB3 TYROBP RAB8A LPCAT2 AP3B1 RASSF2 RHOQ HIVEP2 WNT11 CD1D DCK BAZ2B GNB4 ANKRD13A JUND BMP2K SELPLG BNIP3L WDR1 CDC42EP3 TPT1 SSH2 ABI3 CD3G RNF38 HEBP1 CNN2 ARFGAP3 PPP1CB ARHGEF18 CNR2 LNPEP RB1CC1	down	***
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_DN	0.0000000	0.0000001	0.7881868	0.4672378	2.113303	171	MDM1 HJURP MCM10 GMDS FANCI CHEK2 BUB1B GGCT PHF14 DEPDC1B TTK CDCA2 SLC27A2 ANLN CCDC14 ASPM WDR70 CCNB2 TYMS CDC25A MYL6B COQ3 HMMR DNPH1 EXO1 RPL39L KIF15 KNTC1 TOP2A AURKA VANGL1 TTLL12 PKM FANCD2 B3GNTL1 MAD2L1 CENPO BLM MNAT1 CCDC138 PSRC1 CKS1B CDKN2C ASF1B BCAS4 BIRC5 ATIC POC5 NCAPG TRAP1 TMEM79 SPAG5 SRD5A1 RNASEH2A CHCHD3 GNPAT PSME2 MGMT ANP32E PKP4 FUCA2 MAGOHB RNF187	up	***
GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_DN	0.0000000	0.0000003	0.7614608	-0.3980300	-2.113081	174	FFAR4 RBP4 SLC31A2 LPIN2 OLR1 DLC1 TMEM52B LTA4H SNX10 APIP SYS1 SLC7A7 ECHDC1 FAM89A ANXA5 ABCG1 KLF10 LAIR1 ZMYM6 IL18R1 GRN CD58 ZMIZ1 MOAP1 PPT1 LIMS1 SLC46A2 RNFT1 PLAUR GCHFR ID3 RMDN3 ID2 DUSP1 ELK3 SMAD7 ARL4A CLIP4 GPR157 HES1 BTG1 SLC8A1 GABARAPL2 SLCO2B1 TREM1 DNASE2 TMEM251 SKIL GRB2 GPRIN3 AZI2 BIN2 TFEB DOK3 TESK2 MAP3K2 GPR84 GNB4 ADPGK SLC43A2 MIR155HG CEP170 BLOC1S2 PSME4 SSH2 ISCU GLUL NFKBIA SKI RHOT1 GRB10	down	***
SHEPARD_BMYB_MORPHOLINO_DN	0.0000000	0.0000005	0.7477397	0.4690399	2.112586	159	SCIN FOXM1 FGA HELLS PARPBP GPT2 CCNB1 TOX3 TTK GINS1 CDCA2 IQGAP3 GTSE1 KIF14 ANLN ASPM AURKB CDC6 TPX2 GOLGB1 UHRF1 MCM4 MCM2 PRC1 CLDN1 MELK STRA6 KIF23 MKI67 ITGB4 SLC29A2 FGG KIF11 MCM3 TGM1 MDK LIG1 ACSF2 SOX11 RGS4 MGAT4B FAHD2A CDK1 BIRC5 GMNN PSAT1 DAP DNMT1 COL1A1 COL1A2 DLGAP5 TACC3 PRB1 TK1 GINS2 SLC4A2 CDC20 CENPM HMGA1 LIPG CKAP2 MCM5 NSD1 PFKFB4 RTKN MSH2 SLC2A5 PRIM1 PRR11 MIEN1 BLVRB BMS1 PAXIP1 WDR76	up	***
GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY	0.0000023	0.0000772	0.6272567	-0.4465469	-2.112324	84	HHEX IL1B FYN BAIAP2 FGF10 ELMO1 CDC42 NCF2 RHOA MMRN2 TMEM204 ITGA5 HSPB1 FZD4 CRK FOXC2 ROCK2 ROCK1 AXL SH2D2A NCKAP1L FLT1 WASF2 PIK3R1 VAV3 EPN2 HSP90AA1 PAK2 NRP2 GRB10 FLT4 ABI1 CYBA	down	***
GSE2706_UNSTIM_VS_2H_LPS_DC_DN	0.0000000	0.0000006	0.7477397	-0.4031257	-2.111878	163	CXCL3 IL1A USP12 RAPGEF2 INSIG1 OTUD1 CCRL2 STX11 IL23A ADA BTG2 TNIP3 MAP3K8 RNF144B TTYH2 ZNF697 EPM2AIP1 BTG3 GMEB1 IL10 MAP2K3 CSRNP1 PTGIR PLAUR PXDC1 NFKB1 CDKN1A P2RY2 CXCL2 ATF3 IRAK2 INHBA PIK3R5 TP53BP2 BTG1 NINJ1 HCAR3 CD80 IL6 SAR1A SOCS3 OASL ETV3 ARL5B PTGER4 IRF8 GPR183 FAM43A REL ACSL1 PELI1 FXYD6 EHD1 DUSP5 LRRC32 SOD2 GATA6 GEM ICAM1 IL18RAP TNFAIP8 MIR155HG RIPK2 NUP98 TRAF1 NFKBIA EDN1 LDLR NABP1 PIM3 ZNF385B DCUN1D3 HES4 MSANTD3 LAMP3 SLC43A3 IRF1 NR4A3 CFLAR HIVEP1 NFKBIZ DUSP2 C15orf48	down	***
GCM_DDX5	0.0000222	0.0005476	0.5756103	-0.4816830	-2.111601	57	DYRK1A TRA2B SRSF2 HNRNPU HMGN1 SRSF5 TAF9 DNTTIP2 BCLAF1 AFF1 RABGGTB SLC25A3 ESD DDX5 TCP1 YWHAZ USP7 DDX18 HNRNPD NUP153 HNRNPA2B1 SRSF4 KHDRBS1 SF1 PSMD6 EIF4G2 HNRNPH1 FUS RB1CC1 RAD21 SRP14	down	***
REACTOME_DNA_REPLICATION	0.0000001	0.0000032	0.7195128	0.4908102	2.111485	117	CDC45 MCM10 PRIM2 GINS1 POLE CDC6 E2F3 MCM4 MCM2 ORC1 MCM8 GINS4 CDT1 POLA2 POLD2 MCM7 E2F2 MCM3 LIG1 ORC6 PSMD4 SKP2 ANAPC5 POLE2 GMNN E2F1 PSMB5 DNA2 ANAPC7 FEN1 PSMC4 CCNE1 CDC23 PSMA5 PSME2 GINS2 FZR1 ANAPC1 POLD1 PSMD2 CDC7 PSMB3 RPA1 MCM6 MCM5 GINS3 PSMB4 CCNA2 PRIM1 ANAPC2 RFC5	up	***
MORI_LARGE_PRE_BII_LYMPHOCYTE_DN	0.0000349	0.0008003	0.5573322	-0.4980859	-2.110790	50	GPR65 LY86 SAMHD1 CD22 GGA2 MS4A1 LCP1 MCL1 PTPRC HLA-DQA1 BTG1 CTSS CD83 IRF8 PXK CD74 SERPINB1 MACF1 IGKV1D-39 PIP4K2A ALDH2 SOAT1 CTSH CNR2	down	***
AMIT_SERUM_RESPONSE_40_MCF10A	0.0002006	0.0034513	0.5188481	-0.5651266	-2.110530	30	WEE1 CXCL3 IL1A SLC16A4 CITED2 GM2A KLF6 NR4A1 MCL1 CLIC4 CXCL2 ATF3 DUSP1 JUN FOS FOSB RGS2 GLUL EGR1 NR4A2 FPR1 ZFP36	down	**
GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP	0.0000000	0.0000001	0.8012156	0.4668847	2.109594	172	HELLS CDC45 NEK2 CENPF SLC9A2 BRCA1 DEPDC1B ECE2 CDCA2 E2F8 CDC6 E2F3 TYMS CDC25A UMPS MYBL2 ZWINT AGK LSM5 HAUS5 BZW2 NOP9 TOP2A AURKA EME1 SAE1 CLSPN RAD54L PKM GPSM2 MCM3 CDC25C L3HYPDH THYN1 CKAP2L PPP5C ALG3 GEMIN4 CDKN2C NUSAP1 ASF1B EXOSC2 CENPJ BIRC5 ATIC NCAPG CMTR1 DNA2 EZH2 MTBP NOP2 DGCR6 UBFD1 ILF2 MBD4 KIF20B TM9SF4 CHADL MAGOHB ATAD5 C16orf58 HAUS6 URB1 POLR3E STK39 ATAD2 DUS2 CCNA2 ABCF2 WDR4 SNX7 ZWILCH ARHGAP11A UHRF1BP1 TMEM101 NUBPL GMPR2 UBE2C ERRFI1 RAD1 NAT10 TMEM201 CALU NQO1 PARP2 PCGF6	up	***
GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_UP	0.0000000	0.0000003	0.7749390	-0.4041068	-2.109502	158	SC5D MIR22HG HSD17B11 OTUD1 CITED2 BMPR2 YPEL5 PDCL TMX4 ANXA1 DPEP2 CNST DNAJC3 FBXO7 PTPRM UBL3 ASAH1 NAAA BTG2 RNF125 FBXL5 EVI2B ITPRIP ZNF423 SELL SNORA28 DUSP1 RNF139 PLEK GNAQ IL7R VCPKMT SNN KLRB1 SGK1 AQP3 ETV3 SNX29 MAP4K4 TYROBP JUNB FYTTD1 ATXN1L SKIL FOS KLF2 YPEL2 PTP4A1 TRAPPC10 BIN2 GSAP ZRANB1 ABHD13 IRS2 PIM1 KCNA3 KANSL2 MEGF6 PDE4B EPHA4 EPB41L4A LYZ DCUN1D2 CDC14A TNFSF8 NR4A2 FAM8A1 SLC26A11 CD69 DNAJB1 SPTY2D1 SNRPN MEF2D ITGA6 PTGS2 YOD1 NFKBIZ FBXO33 WHAMM	down	***
BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP	0.0000191	0.0004830	0.5756103	0.5751129	2.109228	46	BUB1B NEK2 IGF2BP3 CENPA ECT2 MCM2 TYMS COCH MKI67 HLTF PKM MCM3 ARPC1A NARF FEN1 TUBG1 DLGAP5 SLC26A2 TWF1 KIAA0100 MCM6	up	***
MODULE_45	0.0000000	0.0000000	1.0276699	-0.3543772	-2.109075	461	SLPI SLC31A2 CD52 FCN1 ASGR1 PECAM1 CD55 SPN IL1B MNDA LPXN PTPRE CYP4B1 LIPA CD44 LY86 LMO2 AQP9 STX11 MAL MKNK1 BCL2A1 NCF2 IL1RN CD22 SLC11A1 TGFBR2 IGSF6 LILRB3 CD8A FGR HEG1 KCNAB1 ANXA1 MAN2B1 BMP1 SLC7A7 ASAH1 KCNK3 ITGA5 ANPEP SLC7A11 LCP1 LAIR1 GRN SLC19A1 SRGN SPI1 CD37 KRT4 SLC5A2 CD58 PPP3CC ZMIZ1 PTPN12 EVI2B MAP2K3 CFD STAT5A TBC1D9 GPA33 KIAA0513 CASP1 PTAFR CPVL FUT7 DENND3 LY96 GMPR LAPTM5 PTPRC SELL CD302 ARC PNRC1 CCND2 M6PR SFTPD CD53 PRF1 FCER1G ALOX5AP CD300C PLEK EVI2A N4BP2L1 SLC6A6 IL7R ARHGDIB HCK NINJ1 EMP3 KCNA5 CD8B ARL6IP5 S1PR4 HCAR3 METAP1 CTSS IL2RB OASL AQP3 CD48 STAT4 RAB31 HK3 RAC2 ST6GALNAC4 PLK3 JUNB ATP11A RHOG IFNGR1 CSTA GLIPR1 DAPK2 GMFG IDS RAB8A SNX1 RPS6KA1 REL TNFRSF10B RASSF2 GFPT2 CST7 SNRK CELF2 CD34 ACSL1 PLCG2 NKG7 MME TGFB1 SFTPC SERPINB1 CD6 FPR2 CD86 NFYC PIM1 SOD2 DOK2 ORM2 CCR1 FCGRT KYNU ANKRD12 RGS2 PLEKHO2 CLEC2B PDE4B SELPLG TNFAIP8 HTR6 IQSEC1 CXCR4 UBE2D1 SP100 MEGF9 IFFO1 S100A4 ICAM3 CTSC KLRK1 MMD P2RX1	down	***
GO_CONDENSED_CHROMOSOME_CENTROMERIC_REGION	0.0000006	0.0000259	0.6594444	0.4998935	2.109026	95	HJURP BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 PLK1 NUF2 AURKB CENPA DYNC1I1 NCAPD2 ZWINT CDT1 SPDL1 BOD1 TP53BP1 KNTC1 BUB1 AURKA CBX3 REC8 KIF2C MAD1L1 CENPW MAD2L1 CENPO SPC24 INCENP KNSTRN CENPH BIRC5 NCAPG SPAG5 RANGAP1 LRWD1 NUP85 CENPK CENPV CKAP5 CENPM	up	***
GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY	0.0008530	0.0112605	0.4772708	-0.6909092	-2.107594	15	ACVRL1 SOSTDC1 BMPR2 TGFBR3 TGFBR2 LTBP4	down	*
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_UP	0.0000000	0.0000002	0.7881868	-0.3970069	-2.107440	178	SMAD6 CD52 SASH1 TSPAN4 DENND5A HHEX GATA2 GPR65 PTPRE RAMP2 HSD17B11 SH2D3C CD44 MYADM AQP9 MANBA CD9 TLCD2 ANXA1 LACTB HBEGF CD33 ASAH1 LUZP1 LITAF SIRPA SPI1 TUBB6 CST3 PTPN12 ST3GAL2 TJP1 TMBIM1 ITIH5 ITGAX PTGER3 PLEK KLRD1 MAPRE2 HCK PROCR PRCP RNF149 CABLES1 RAB31 KCTD12 TYROBP SELENBP1 OGFRL1 DYM TAGLN2 CD34 ACSL1 CD151 RHOQ RRAS IRF5 SERPINB1 TSC22D1 CD81 GABARAPL1 PLA2G15 CALHM2 S100A4 GLUL RORA THEMIS2 WDFY3 RNH1 CNN2	down	***
GNF2_JAK1	0.0002444	0.0040793	0.4984931	-0.5789240	-2.107007	27	GPR65 FYN CTSW PTPRC PPP2R5C KLRB1 JAK1 PTGER2 SNRK BIN2 GSAP CLEC2B CYTH1 PRKCH ITGAL	down	**
MORF_ESPL1	0.0000104	0.0002877	0.5933255	0.5590618	2.106653	51	FOXM1 BUB1B PLK1 AURKB ESPL1 MCM2 TYMS ZWINT NUDT1 BUB1 CCT5 POLA2 KIF11 MCM3 DNAJC9 SSBP1 GOT2 FEN1 DNMT1 SNRPA LMNB2 SSRP1	up	***
PID_FOXM1_PATHWAY	0.0000162	0.0004218	0.5756103	0.5981196	2.105890	38	ONECUT1 FOXM1 CHEK2 NEK2 CCNB1 CENPF CDK4 PLK1 AURKB CENPA CCNB2 XRCC1 SKP2 CKS1B CDK1 BIRC5 CCNE1	up	***
GO_MICROTUBULE_BUNDLE_FORMATION	0.0000022	0.0000766	0.6272567	0.5218200	2.105727	70	KIF20A SPAG17 TTC26 PLK1 PRC1 DNAI1 RSPH1 ARMC4 SPAG16 HYDIN TEKT2 CCDC114 DNAH8 GAS8 DNAAF3 CCDC40 PSRC1 DRC1 LRGUK LRRC6 DNAH5 DNAH7 CCDC151 IQCG SPAG1 DNAJB13 AAAS TTLL3 CDK5RAP2 DNAI2 TTLL6 RSPH4A NAV1 DNAH1 MARK4 ZMYND10 CLASP1 ARMC2 DNAAF1 WDR63	up	***
MITSIADES_RESPONSE_TO_APLIDIN_DN	0.0000000	0.0000000	0.8266573	0.4493937	2.105681	225	TRIP13 FOXM1 HELLS HJURP FANCI DEPTOR BUB1B NEK2 CCNB1 CENPF DROSHA KIF18B GINS1 RACGAP1 KIF14 GMPS ASPM CDCA8 CENPA PTTG1 ECT2 GPI TPX2 MCM4 PRKCA MCM2 TYMS MYBL2 FERMT1 NCAPD2 ZFP64 AVL9 ZWINT CDT1 MELK CHAF1A MKI67 BUB1 TOP2A AURKA CBX3 TPR RSRC1 RRM2 PRKDC TRRAP TOPBP1 AHCY CAD BLM SKP2 PARP1 CASP6 NCAPG2 NUSAP1 TMEM106C CBX5 URI1 HDGF BIRC5 AP3D1 NCAPG NUP205 FANCG CCNE1 EDEM3 DLGAP5 TACC3 SNRPA SLC37A4 AGPAT5 PSMD2 CDC7 SUPT16H PALB2 KIAA0100 ACLY CKAP2 MCM5 HEATR1 ADD3 DDAH1 MSH2 CCNA2 NBPF14 CDC42BPA SHCBP1 TPGS2 AGBL5 WDR76 PGAM1 SMC2 EIF4G1	up	***
GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN	0.0000000	0.0000003	0.7614608	-0.3958502	-2.105358	184	CXCL3 ADTRP SOWAHC ZC3H12C LHCGR EGR2 CCRL2 BAG4 CITED2 CDC42EP2 IER2 CCNL1 BTG2 MAP3K8 KLF6 MCL1 TIPARP IL10 CSRNP1 TLE4 ACSL3 AOC3 ID3 ZFAND5 CXCL2 ATF3 ID2 CCL4 PNRC1 DUSP1 MAFF RASGEF1B PROCR NRROS RPS6KA2 SLC25A25 RYBP SGK1 SOCS3 ETV3 JUN ARL5B HSPA1B JUNB RCAN1 PPP1R15A PTGER4 SKIL IFRD1 OSM MALT1 ATL2 REL FOS PELI1 CDK17 MAPK8 ATPAF1 EHD1 TGIF1 TEX30 DUSP5 PIM1 GPR84 TOB1 PDE4B PHLPP2 SMAD2 C3orf38 CTTNBP2NL IER5 SETDB2 MEX3C GPD1L TRAF1 NFKBIA TLK2 TNFSF9 NABP1 ARFGAP3 DNAJA2 HERPUD1 EGR1 ATF2 CLEC4E OSGIN2 SLC38A2 ZFP36 YRDC DNAJB4 CD69 TRIM13 IRF1 CHKA CFLAR PTGS2 NFKBIZ DUSP2 RNF19B ST3GAL1 SLAMF7 IL10RA FEM1C	down	***
PUJANA_BRCA_CENTERED_NETWORK	0.0000003	0.0000117	0.6749629	0.4936911	2.104671	107	FANCI CHEK2 TIMELESS TTF2 NDC80 BRCA1 GINS1 POLE ESPL1 TFDP2 RBBP8 MCM4 MCM2 MYBL2 NCAPD2 HMMR CHAF1A TOP2A AURKA PRKDC RAD54L LMNB1 TOPBP1 MAD2L1 RAD51AP1 CAD BLM CNOT3 SKP2 CDK1 UNG DNA2 EZH2 DNMT1 SNRPA CDC7 CPSF4 CDC20 RPA1 MCM6 TBCA MCM5 AATF TCERG1 MSH2 CCNA2 SMC2 TCF3 PAICS UBE2C RAD1	up	***
GO_CARDIAC_MUSCLE_CELL_PROLIFERATION	0.0000683	0.0014004	0.5384341	-0.5000088	-2.103312	46	RBP4 PRKAR1A TGFBR3 TGFBR2 TBX2 FOXC2 TBX5 MIR17HG TGFB2 RBPJ NOTCH1 SAV1 PIM1 MEIS1 GATA6 RXRA FGF2 PTEN FGFR1 MIR548C ZFPM2 MAPK1 NOG JARID2 BMPR1A YAP1 ERBB4	down	**
GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP	0.0000000	0.0000005	0.7614608	-0.3965542	-2.103123	182	SEMA6B EPAS1 ABHD5 OLR1 TAL1 LPXN THBD PID1 RCOR1 AATK PPP4R1 GFOD1 RTN3 INPP5A C5AR1 MSRA CD9 AGPAT4 USP47 PFDN1 PPM1D TRIB1 CASP9 AVPI1 HBEGF LMNA CHMP1B ANXA5 REV3L PDE4D TIPARP ZMIZ1 FOXO1 PAQR5 DAB2 SLC7A8 SSH1 PDE3B VIM IL7R MMP19 HGSNAT CLN8 PKIG SOCS3 HECA PHF10 LTBP2 MAP4K4 IFNGR1 GPR183 UNC13B APH1B	down	***
HALLMARK_INFLAMMATORY_RESPONSE	0.0000000	0.0000003	0.7614608	-0.3958716	-2.102834	179	SLC31A2 EREG IL1A OLR1 CD55 IL1B PTPRE CCRL2 CALCRL AQP9 C5AR1 MARCO SCARF1 ATP2B1 HBEGF SGMS2 BEST1 ITGA5 BTG2 RNF144B NMUR1 KLF6 IL18R1 SLC7A2 IL10 MSR1 PTGIR CCL22 MEFV PTAFR PLAUR TNFSF15 NFKB1 CDKN1A P2RY2 IRAK2 SELL AXL INHBA IL7R PIK3R5 EMP3 IL6 PSEN1 IL2RB CD48 HRH1 RHOG PTGER4 CCR7 GPR183 OSM PTGER2 TNFRSF9 IFNAR1 KCNA3 PDE4B CCL20 ICAM1 IL18 IL18RAP SLC31A1 RIPK2 NLRP3 NFKBIA EDN1 TNFSF9 KIF1B LDLR SPHK1 ABI1 CD70 SERPINE1	down	***
GSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_UP	0.0000000	0.0000008	0.7477397	-0.4006455	-2.102765	165	SLC31A2 CD300LF HMOX1 FABP4 LIPA ARL8B SLC15A3 FUCA1 LAMP1 ACER3 NCEH1 UBL3 CD33 ADAM17 HLX STOM NDEL1 APOC1 PDGFA RAB14 IL10 SDCBP DAB2 MAFG ID2 PLEKHB2 PRF1 PLEK UBASH3B ANXA3 LACC1 FMNL2 SNAP23 SLCO2B1 JUN SNX29 PLK3 EEA1 ATP6V0D1 TIMP2 CRYZL1 SBF2 CD86 PLEKHO2 SLC43A2 IL18 CGRRF1 CEP170 MS4A4A SAMSN1 TMCC3 THEMIS2 NRP2 DOCK4 EHD4 PHYH DUSP6 SPPL2A CAPZB TREM2 PTGS1 FXYD5 PDE7B SERP1 ATP8A1 FNDC3A SKAP2 CPNE2 PDPN CFLAR LRP1 SLC29A3	down	***
GSE3982_MAC_VS_TH2_UP	0.0000000	0.0000004	0.7614608	-0.3959170	-2.101863	174	DNAH17 SWAP70 FCN1 TSPAN4 SLC47A1 USP12 WFDC1 FABP4 ENG FIG4 HSD17B11 EGR2 PLEKHF2 CCRL2 RASAL2 FUCA1 FRAT1 SLC11A1 DPEP2 MAN2B1 SLC7A7 ANPEP LAMTOR3 SPRY2 CCL22 LIN7C CPVL UBTD1 MVB12B MAP1LC3B SOCS5 SPAG9 CDKN1A P2RY2 PAPSS1 FRMD4A CAPZA2 CCSER2 INHBA SMNDC1 NRBF2 CLN8 TBC1D5 PRCP HCAR3 PDHX PSEN1 RHOBTB2 TREM1 ENPP4 SPATA2L MORF4L1 SLC25A24 AZI2 CD74 PPP2CB STXBP3 VAV3 GALC HBP1	down	***
GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP	0.0000000	0.0000002	0.7749390	-0.3952711	-2.101648	175	HMOX1 USP12 IL1B MIR22HG ENG BMPR2 CDC42 HEG1 LMNA BTG2 ANPEP SERPINB9 RBM4 SRSF2 CRK CLK1 PDGFA TIPARP RHOB MAP2K3 FABP5 HNRNPA3 LIMS1 PXDC1 THBS1 CCL3 NFKB1 CDKN1A RBMS1 CXCL2 ATF3 CCL4 DUSP1 TP53BP2 SRF EMP3 PRKRA CREM OASL SRSF3 SERPINB8 SH3BP5 RAB31 JUNB PPP1R15A DHX15 CD83 ATP13A3 YWHAZ RUNX3 TEX30 DUSP5 CD86 PIM1 PPP3R1 MACF1 GEM ICAM1 SP100 TRAF1 S100A4 BCAT1 SFPQ DNAJB5 SERPINE1 FUS S100A8 ZFP36 CD69 DNAJB1 LAMTOR5 TRIM25 MSC CD4 KRT10 DUSP2 RNF19B EMP1 IVNS1ABP PNP	down	***
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN	0.0000000	0.0000008	0.7477397	0.4748139	2.100277	140	TRIP13 SLC16A14 HP FOXM1 KIF20A HJURP CENPF FRK MND1 KIF18B DEPDC1B TTK GINS1 E2F8 KIF14 ANLN ASPM OTOGL CDCA8 TBX19 GAPDH BCL2L14 SLC7A9 TMEM132D DTL KIF27 MYL6B CLDN1 MELK HMMR CEP55 MKI67 KIF15 BUB1 AURKA METTL7B MYO10 SLC2A10 C1orf226 KIF2C CDCA5	up	***
ANDERSEN_CHOLANGIOCARCINOMA_CLASS1	0.0000128	0.0003449	0.5933255	0.5573207	2.100092	51	PKHD1 HKDC1 MPP6 PSPH GAL3ST1 SPP1 SLC4A3 WNK2 SYT12 SMYD2 DCDC2 MCCC2 NME5 OXTR RGS4 CLDN9 DBNDD1 VN1R1 GMNN CTXN1 SCTR PGBD5 HNF1B ANKRD1 PTHLH PATZ1 LPGAT1 LOXL4	up	***
GO_CONDENSED_NUCLEAR_CHROMOSOME	0.0000026	0.0000873	0.6272567	0.5203906	2.099958	70	BUB1B NEK2 CCNB1 NDC80 BRCA1 PLK1 NUF2 AURKB CENPA NCAPD2 RSPH1 STAG3 BUB1 AURKA REC8 SYCP2 HORMAD1 TOPBP1 CHEK1 CENPO BLM INCENP TUBG1 RAD9A RAD50 CENPK NOL6 ADD3 RCC1 MSH4 RAD51 CHMP1A NCAPD3 RAD1 RRS1 SS18L1 NCAPH MLH3 DSN1 KIFAP3	up	***
GO_SPROUTING_ANGIOGENESIS	0.0000008	0.0000310	0.6594444	-0.4172578	-2.098961	111	SEMA6A ACVRL1 HMOX1 TEK ADTRP GATA2 BMPER RAMP2 CDH13 TBXA2R CDC42 MIR27B RHOA ANXA1 MIR146A MMRN2 ITGA5 CLEC14A NR4A1 AKT3 FOXC2 IL10 NRARP KLF4 THBS1 ADAMTS9 MIR24-2 RECK PIK3C2A SRF FLT1 NOTCH1 JAK1 RHOJ KLF2 JMJD6 MIR23A MIA3 FGF2 EPN2 EPHA2 PARVA GLUL FLT4 STARD13 GREM1 ITGB1 MIR2355 EFNB2	down	***
GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP	0.0000000	0.0000008	0.7477397	-0.4033655	-2.098839	154	CPEB2 SIK1 BAIAP2 PRAM1 VAMP2 CCNL1 SBDS BTG2 EIF5 NR4A1 ADRB2 HNRNPDL CLK1 MTHFR GPR4 CSRNP1 AGO3 KLF4 SPAG9 NR1D2 ATF3 CLK4 SMAD7 ELMSAN1 GCA MAFF SLC25A25 CREM SF3B1 ARL5B PLK3 UHRF2 DUSP8 SKIL DDX5 FRYL STX5 REL HOMER1 TNFRSF10B TINF2 SLC3A2 TGIF1 CDC37L1 TAGAP CRY1 TAGLN SERTAD1 TRAF1 RND1 KATNA1 FNBP4 PDE4A TTC19 ZFAND2A EIF4A2 HNRNPH1 YTHDC1 EGR1 NR4A2 GAS5 SLC38A2	down	***
GNF2_PA2G4	0.0000023	0.0000793	0.6272567	0.5142454	2.097608	75	BUB1B NUP107 NDC80 CDK4 GMPS MCM4 CCT6A CCT2 LSM5 RANBP1 MELK MRPL15 CCT5 MCM7 MRPL3 MCM3 CAD ETFA CKS1B SSBP1 CCT3 GMNN SF3B3 SNRPE PA2G4 CHCHD3 SNRPA SSRP1 CENPM MCM5 SNRPD1 LSM4 BANF1	up	***
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP	0.0000000	0.0000007	0.7477397	0.4663868	2.097567	161	STRC CEACAM1 TICRR BUB1B CENPF PBK CLGN NDC80 SRGAP3 TTK KIF14 ANLN ASPM NUF2 CDCA8 PTTG1 TPX2 TFDP2 CCNB2 RAD54B PRC1 CCNF HMMR CEP55 GFPT1 MKI67 KIF15 KNTC1 BUB1 TOP2A CLSPN RRM2 RAD54L KIF11 GPSM2 CDC25C CHEK1 CKAP2L NEB CCDC136 INCENP GPX8 CKS1B NCAPG2 PLOD2 CDK1 PPIC BIRC5 ADAP1 NCAPG NEIL3 OCIAD2 RTP4 HSPA4L TACC3 KIF22 CCDC146 LCLAT1	up	***
GO_MITOTIC_CELL_CYCLE_CHECKPOINT	0.0000000	0.0000004	0.7614608	0.4697021	2.097216	152	HMGA2 TRIP13 TICRR CHEK2 BUB1B CCNB1 CENPF NDC80 BRCA1 TTK BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB CDC6 TFDP2 ORC1 ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 KNTC1 BUB1 TOP2A AURKA EME1 TPR MAD1L1 CLSPN PRKDC CDC25C SOX4 EME2 TOPBP1 NEK11 MAD2L1 MDM2 BLM PML CNOT3 CDK1 RFWD3 E2F1 CNOT11 MAD2L2 KLHL22	up	***
REACTOME_UNWINDING_OF_DNA	0.0000342	0.0007891	0.5573322	0.8056981	2.096709	12	CDC45 GINS1 MCM4 MCM2 MCM8 GINS4 MCM7 MCM3 GINS2 MCM6 MCM5 GINS3	up	***
GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_UP	0.0000000	0.0000007	0.7477397	-0.4027548	-2.095800	159	SPN SNX10 TTC7B CD44 MYADM MEF2A IL1RL1 GNPTAB ZEB2 ANXA1 ATP2B1 CYP17A1 LATS2 ENTPD1 ZDHHC2 LITAF LAIR1 IL18R1 DUSP3 PPT1 AHNAK PLEKHM3 OSTF1 CLIC4 CTSD ITGAX HOPX ATP6V0D2 ID2 TEF PRF1 IL7R PIK3R5 CALM2 EMP3 MYLIP CD80 HCST NDNF CD48 CCDC50 EEA1 DAPK2 COBLL1 TBX21 GPRIN3 NKG7 KLRC2 PIK3AP1 SMPDL3B CHPT1 GSAP ATXN1 LGALS3 POLK IL18RAP ARHGAP18 HAVCR2 KLRK1 RORA CX3CR1 UBA6 ITGAL ITGB1 PIK3CG S1PR5 ATP2B4 RPA2 DOCK5 CD226 TTC39B RNF19B BMPR1A MYO1F MYO5A EMP1 TNFRSF1B F2RL2 GZMK SOS2	down	***
chr7q22	0.0000000	0.0000025	0.7195128	0.4808257	2.095034	125	SLC26A4 MYH16 AGFG2 AP1S1 SPDYE6 BAIAP2L1 GPC2 ZNF3 CYP3A5 SPDYE3 STAG3 DPY19L2P2 AP4M1 PUS7 MCM7 TFR2 TRRAP PPP1R35 ZNHIT1 ZKSCAN1 CLDN15 ARPC1A ZSCAN25 SPDYE2 ZNF789 TAF6 NAPEPLD ZKSCAN5 GAL3ST4 GIGYF1 ZSCAN21 LRWD1 FAM200A COPS6 CPSF4 EFCAB10 POP7 ALKBH4 COL26A1 POLR2J SRRT TRIM56 SRPK2 LRRC17 POLR2J3 LRCH4 RASA4DP DUS4L RASA4B PMS2P1 COG5 EIF4BP6 PDAP1 TRIP6 RNU6-1322P FIS1 SPDYE2B EPHB4 FAM185A ARMC10 RASA4 AZGP1 NPTX2 CNPY4 TSC22D4 PCOLCE-AS1 CYP3A7 PLOD3 ORC5 SLC12A9 LAMTOR4 MUC12 KPNA7 DNAJC2 MOSPD3 PCOLCE TRIM4 STAG3L5P RWDD4P1 PMPCB PSMC2	up	***
GO_MITOTIC_SPINDLE_ORGANIZATION	0.0000005	0.0000185	0.6749629	0.4989754	2.094873	93	SPICE1 CHEK2 NEK2 CCNB1 NDC80 TTK RACGAP1 STIL MSTO1 PLK1 NUF2 AURKB TPX2 MYBL2 PRC1 DCTN2 WDR62 KIF23 KIF3B MAP10 AURKA TPR POC1A FSD1 KIF11 GPSM2 PSRC1 CEP97 BIRC5 KIF2A KPNB1 CEP192 TUBG1 TACC3 CDC20 TUBG2 AAAS EFHC1 CHMP4C RCC1 NUP62 CHMP1A CHMP2A CENPE GOLGA2 MAP9 CLASP1 DRG1 DYNC1H1 WRAP73 PCNT	up	***
GO_POSITIVE_REGULATION_OF_RESPONSE_TO_WOUNDING	0.0000425	0.0009450	0.5573322	-0.4831026	-2.094672	56	THBD TBXA2R TGFBR2 SCARF1 CD36 ANXA1 HBEGF CLEC7A NFE2L2 NDEL1 GRN FOXC2 THBS1 SELP HPSE TLR4 PLEK KANK1 CNTF DUOX1 ENPP4 PRKCE	down	***
GO_HEART_TRABECULA_MORPHOGENESIS	0.0003044	0.0049522	0.4984931	-0.5709089	-2.094061	28	RBP4 TEK CCM2L ENG S1PR1 TGFBR3 HEG1 TGFB2 SRF RBPJ NOTCH1	down	**
KEGG_HEMATOPOIETIC_CELL_LINEAGE	0.0000043	0.0001355	0.6105269	-0.4609205	-2.093608	70	IL1A CD55 IL1B CD44 CD1C CD9 CD22 CD8A CD36 CD5 CD33 ITGA5 ANPEP MS4A1 TFRC CD37 EPOR IL7R CD8B IL6 CD7 CD34 CR1 MME CD1D CD19 KIT CD1E CD3G CSF2 HLA-DRB1 IL5 CD3E CSF3 ITGA6 CD4 GP5	down	***
GNF2_RAN	0.0000029	0.0000962	0.6272567	0.5107933	2.093424	79	KIF20A GMPS CCT6A NCAPD2 CCT2 NME1 RANBP1 MELK MRPL15 CCT5 PRKDC MRPL3 MCM3 EMG1 ETFA CKS1B SSBP1 CCT3 ATIC SNRPE PA2G4 POLR2H PSMA5 SNRPA SSRP1 CCT7 CDC20 MRPS33 SNRPD1 LSM4 PRMT5 BANF1 SNRPD2 PAICS SNRPC ADSL MSH6 XRCC5 NAE1 LRPPRC MTHFD2 CTPS1 BUB3 MRPL35 RFC3 RFC4	up	***
GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP	0.0000000	0.0000009	0.7477397	0.4663577	2.092983	158	TRIP13 DDX11 FOXM1 HJURP TROAP XYLB PLEKHA5 POLQ APOLD1 MUC16 DEPDC1 SORD GTSE1 DBF4B TRAIP DNMT3B ASPM ESPL1 TPX2 CCNB2 TYMS CDC25A MYBL2 CCNF SPPL2B HAUS5 WDR62 MELK EXO1 MKI67 FANCA KIF2C CLSPN RRM2 RAD54L ORC6 CC2D1A PKMYT1 PTGDR2 SNAPC4 FADS2 SLC25A10 HSPBP1 CDKN2C FASTK NUSAP1 ASF1B CDK1 CEP97 ATP2A1 RECQL4 SERHL2 NRGN DLGAP5 GSS PTGES2 TK1 LRRC20 ATAD5 PPME1 CENPM AAAS GBF1 MRPL28 KPTN CACNB3 CHRNA3 ETV6 SLC1A5 SPAG4 CEP85 MICAL3	up	***
BASAKI_YBX1_TARGETS_UP	0.0000000	0.0000000	0.8753251	0.4425689	2.091494	256	DKK1 TRIP13 DDX11 KIF20A HJURP MCM10 FANCI S100A2 BUB1B NEK2 CCNB1 PBK NDC80 DEPDC1 DEPDC1B GINS1 GTSE1 FOXE1 ANLN ASPM NDUFS6 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 CCNB2 UHRF1 MCM4 MCM2 TYMS PRC1 DTL MIS18A NCAPD2 ZWINT SPDL1 MELK KIF23 CEP55 CHAF1A LAMC2 MKI67 BUB1 AURKA POLA2 SAE1 KIF2C MCM7 CENPW PRKDC WDHD1 MCM3 CHEK1 DNAJC9 ORC6 MAD2L1 CENPO SPC24 CAD COMMD4 FLNB WWC1 KNSTRN ASF1B OSMR CDK1 TNFRSF21 BIRC5 CCM2 UNG FEN1 DIAPH3 RANGAP1 MYO19 ILF2 SMG5 LMNB2 TUBB2A KIF22 TK1 DTYMK GINS2 PSMD2 DCUN1D5 CDC20 CENPM MCM5 ZNF599 SLC1A5 CCNA2 SHCBP1 RFC5 WDR4 WDR77 RAD51 ZWILCH ZNF71 RBM19 SMC2 RHOD SMPD4 MTHFD1 FRMD6 CBWD1 PRPF3 FGFBP1 UBE2C KRT80 E2F7 DDB2 RRS1 ZNF367 NUP93	up	***
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP	0.0000000	0.0000000	0.9865463	0.4285932	2.091074	391	ALDH3B2 PRR15 PPM1H PRLR SLC16A14 ENTPD2 EPHB3 BIK LAD1 ZG16B EPN3 GALNT6 PAGR1 IQCE GGCT TOX3 PLEKHA6 TTC39A SPDEF TFF3 CREB3L4 PRR15L HILPDA FA2H ABCA12 BCAS1 FLAD1 EFNA4 TRIB3 ANKRD22 C4orf19 AGR2 SPINT2 LSR CA12 GRB7 MARVELD3 PIP4K2C EPS8L1 C6orf132 TJP3 RSPH1 TMEM41A ZNF74 MAP7 FOXA1 PAQR4 CBLC MSX2 TMEM184A SYNE4 P4HTM SYCP2 SLC29A2 SFI1 ICA1 HOOK1 BLOC1S1 MCCC2 AP1M2 CD24 SIDT1 SLC9A3R1 PROM2 SPINT1 ZKSCAN1 EHF DDR1 RABEP2 GRHL2 SYMPK NOL3 IDH2 DHRS13 TMED3 TTC9 CAPN8 MB KIAA0556 EPHA1 ESRP1 PLCH1 TNK2 AAGAB SUN1 ABCC11 CDH3 TMEM79 RAB11FIP4 RALGPS1 KIAA1211L MYO5B FAM102A TSPAN1 ACVR1B IRF6 ULK1 ST14 FANCF DHRS4-AS1 LLGL2 PKP3 COG7 ROGDI C9orf152 MGMT TP53TG1 HIP1R HID1 KRT19 ELMO3 FXYD3 ESR1 TMEM30B JTB ZBTB7B RMND5B UBQLN4 USP18 ERBB3 PPP1R3D CHMP4C MYO5C MRPL41 ANXA9 SSH3 CACNB3 SCYL3 PRODH TBC1D30 RAB3D OVOL2 SUOX PRKD2 ANK3 TMEM45B TC2N PATZ1 EPCAM DOK7 PRSS8 ATP6AP1 CDH1 GRHL1 BLVRB HOOK2 ARRDC1 TNKS1BP1 SLC25A29 CHMP2A ERBB2 ENPP5 ADCY6 CAMSAP3 RHPN1 CGN RAB25 KIAA1522 DCAF11 MUC1 PLXNB1 AZGP1 ARHGAP8 PPP1R16A TRAPPC6A CYHR1 CAMK2N1 CXorf40A NR2F6 C11orf80 ARHGEF5 RAB40C SIGIRR RUSC1 TMEM229B TRPS1 TRPM4 PGAP3 MARVELD2 STARD10 OVOL1 CCDC6	up	***
GO_POSITIVE_REGULATION_OF_WOUND_HEALING	0.0000808	0.0016164	0.5384341	-0.4970731	-2.090963	46	THBD TBXA2R TGFBR2 CD36 ANXA1 HBEGF CLEC7A NFE2L2 FOXC2 THBS1 SELP HPSE TLR4 PLEK KANK1 DUOX1 ENPP4 PRKCE	down	**
REACTOME_KINESINS	0.0000156	0.0004086	0.5756103	0.5548055	2.090614	51	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 KIF27 KIF23 KIF15 KIF3B KIF2C KIF11 KIF3C KIF5A KIF19 KIF2A TUBB2A TUBA3D KIF22 TUBA8 KIF21A KIF20B KLC2 KLC4 KIF21B	up	***
GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_UP	0.0000000	0.0000006	0.7477397	0.4599653	2.090569	178	CEACAM1 KIF20A CDH17 CHEK2 C21orf58 GGCT TBRG4 CDCA2 SLC27A2 STIL PLK1 CCNB2 HOXB7 MCM2 CDC25A MYBL2 CCNF ANKRD36B COQ3 CDT1 DNAH14 RANBP1 NDUFB8 EXO1 KNTC1 EME1 TMEM177 POLA2 E2F2 POC1A C1RL ERAL1 CKAP2L SPC24 GLE1 COQ9 CKLF MRPL37 ULBP2 PSAT1 SAPCD2 SLC12A8 DIAPH3 LAPTM4B MYO19 IFI27L2 SNRPA COL9A2 COMMD7 TMEM237 KIF20B KLHL23 WDR34 MGME1 PPCDC ROMO1 HAX1 SUOX LSM4 RRP36 SUV39H2 LRP11 CISD3 CCDC167 FARSB TPGS2 ZWILCH COX5B ARHGAP11A PAXIP1 NDUFA8 IKZF4 SNUPN ARHGEF39 MTHFD1 BCAT2 E2F7 C4orf46 MLLT11 ZDHHC13 MRPL12 EIF2B1 COMTD1 FAM111B DCLRE1B WDR5 TMEM214 HINT2 LRP8 XRCC5 HNRNPAB DHPS TMEM14A PUSL1 SKA3 ITPA NDUFA9 HMBS	up	***
GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME	0.0000048	0.0001505	0.6105269	0.5248453	2.090527	66	NDC80 TTK NABP2 PLK1 AURKB CENPA CCT6A MCM8 CDT1 CCT2 SPDL1 RUVBL2 BOD1 CCT5 ATR CDCA5 PIH1D1 CDK1 CCT3 EZH2 TRAPPC12 MTBP CENPQ ESCO2 LRWD1 ESR1 CCT7 PPHLN1 RPA1	up	***
GSE14415_INDUCED_TREG_VS_TCONV_UP	0.0000000	0.0000008	0.7477397	0.4670679	2.090257	156	TRIP13 CEP72 CDC45 MCM10 TROAP POLQ PBK KIF18B PRIM2 PHGDH GINS1 TRAIP PLK1 NUF2 CDCA8 AURKB CCNB2 FIGNL1 SHMT2 SPDL1 NME1 RANBP1 HMMR NUDT1 MKI67 KIF15 BUB1 AURKA MCM7 RRM2 CDC25C MAD2L1 CKAP2L RAD51AP1 SPC24 DSCC1 PPIL1 CKS1B CDKN2C ASF1B CDK1 POLE2 BIRC5 GMNN ADAP1 POLR3K SLC25A13 PSAT1 NEIL3 SPAG5 ETFB CENPP PSMA5 SNRPA POLL KIF22 CHTF18	up	***
GO_DNA_REPLICATION_ORIGIN_BINDING	0.0000255	0.0006109	0.5756103	0.6800740	2.088997	23	DDX11 CDC45 MCM10 CDC6 MCM4 MCM2 ORC1 MCM8 MCM7 MCM3 ORC6	up	***
GO_CHROMATIN_ASSEMBLY	0.0000070	0.0002059	0.6105269	0.5144403	2.088727	72	HMGA2 HELLS HJURP RUVBL1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A CHAF1A CENPL TPR CENPW CHAF1B CENPO ASF1B CENPH CENPP HIRA CENPQ NOC2L CENPK CENPV CENPM HMGA1 CENPT	up	***
GUENTHER_GROWTH_SPHERICAL_VS_ADHERENT_DN	0.0008061	0.0107468	0.4772708	-0.5918345	-2.087410	24	CD44 CAV1 NR3C1 TGFBR2 ANXA5 CASP1 PLAUR GAA CTSD TGFB2	down	*
GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000000	0.0000004	0.7614608	-0.3921435	-2.087045	177	CXCL16 DENND5A GPR65 RAPGEF2 YPEL5 STX11 USP47 HPS5 PDE2A EIF4A1 TNFRSF8 B3GNT5 SLC36A4 BZW1 MAP3K8 NFE2L2 TMEM41B PDE4D TFRC TIPARP DIABLO ZMIZ1 MAP2K3 CDADC1 PLAUR MAFG SNIP1 CDKN1A GGTLC1 C9orf72 PLEKHB2 DNTTIP2 OXSR1 N4BP1 PIK3R5 MAFF SEC31A TAF13 LACC1 EMP3 PPP2CA PSEN1 RAB8B ETV3 MAP4K4 WTAP PNPLA8 CD83 HSPA13 ATP13A3 HIVEP2 RBKS ZBTB1 DUSP5 CTNNAL1 PHF19 SOD2 THAP9 ZNF267 PDE4B RLF WDR1 IER5 METTL21A ARIH1 TXNDC11 NUP98 G3BP2 NFKBIA MAFK	down	***
chr13q32	0.0001336	0.0024511	0.5188481	-0.5432502	-2.086642	35	STK24-AS1 CLYBL DNAJC3 UBAC2-AS1 RNA5SP37 ABCC4 DOCK9 TM9SF2 STK24 MTCYBP3 MTND5P2 DOCK9-AS1 UBAC2 MBNL2 GPR183 GPR18 PCCA IPO5	down	**
GO_CONDENSED_CHROMOSOME	0.0000000	0.0000005	0.7614608	0.4614673	2.086375	174	DDX11 HJURP STAG3L2 BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 BRCA1 L3MBTL1 PLK1 NUF2 AURKB CENPA DYNC1I1 NCAPD2 ZWINT CDT1 SPDL1 TOP3B RSPH1 STAG3 MKI67 BOD1 TP53BP1 KNTC1 BUB1 TOP2A AURKA CBX3 REC8 SYCP2 KIF2C MAD1L1 CENPW CDCA5 FANCD2 HORMAD1 TOPBP1 CHEK1 MAD2L1 CENPO SPC24 BLM PES1 INCENP KNSTRN NCAPG2 CENPH BIRC5 NCAPG SPAG5 RANGAP1 TUBG1 RAD9A LRWD1 NUP85 RAD50 CENPK STAG3L4 CENPV CKAP5 CENPM NOL6 CENPT ADD3 RCC1 ESRRB MSH4 BANF1 RAD51 ZWILCH CHMP1A SMC2 CENPE NCAPD3 RAD1 RRS1 CLASP1 SS18L1 NCAPH	up	***
KIM_WT1_TARGETS_UP	0.0000000	0.0000002	0.7749390	-0.3857255	-2.085988	202	SLPI EREG CSDC2 SOWAHC TBX3 PTPRE RCOR1 CD44 BAIAP2 FOSL1 BMPR2 NR3C1 RGPD5 OTUD4 TRIB1 IER2 ARHGAP29 ATP2B1 SH2B3 HBEGF LITAF KLF10 GLS PTX3 NR4A1 TNS1 SPRY2 ZEB1 ZNF365 PDGFA ZMIZ1 EVI2B MAP2K3 SRSF5 PLAUR KLF9 THBS1 NFKB1 ARC LBH INHBA MAFF SRF TRGC2 AREG SGK1 HPGDS SH3BP5 ETS1 JUNB FERMT2 GLIPR1 CD83 SPATA2L ATP13A3 GFPT2 CDK17 MBP SRSF6 FLNC DUSP5 NAB1 UTP3 PHLPP2 GEM ARAP2 PDLIM5 SF1 TIAM1 ACTB EPHA2 NFKBIA TIMP3 B3GNT2 GRB10 DNAJB5 SPHK1 EGR1 SERPINE1 HMGCS1 MYH10 ZYX ATP1B1	down	***
GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP	0.0000000	0.0000006	0.7477397	-0.3920539	-2.085167	184	IL1A SOWAHC GLIPR2 IL1B SNX10 CAV1 MYADM CALCRL PLEKHA1 BCL2A1 IL1RN MOB1B IER2 TRA2B SLC7A7 SLC25A17 PPP1R15B MAP3K8 SRGN PDGFA RHOB IL10 MSR1 STAT5A RAB12 PLAUR VASP NFKB1 CDKN1A CXCL2 SELP C9orf72 CCND2 DSTN N4BP1 KPNA3 PROCR UFM1 PNO1 SOCS3 MTMR14 KCTD12 MAP4K4 HSPA1B JUNB WTAP IFRD1 DDX5 ACSL1 AGFG1 RHOQ PELI1 YTHDF3 PBRM1 EHD1 IFNAR1 PIM1 STK40 IST1 ICAM1 SLC31A1 SERTAD1 CEBPD HSP90AA1 TAB2 RBM18 HNRNPK MCOLN2 TNFSF9 NAA15 MT2A PPP1CB HNRNPH1 SERPINE1 SSB EFNB2 UBE2N KCMF1 TES DLD FNDC3A PDPN PTGS2 NFKBIZ DUSP2 RNF19B	down	***
RHODES_CANCER_META_SIGNATURE	0.0000060	0.0001817	0.6105269	0.5416437	2.084969	55	PLK1 TPX2 COPB2 NME1 PAFAH1B3 TOP2A CCT5 CBX3 MRPL3 MCM3 SOX4 KDELR2 AHCY CDK1 SSBP1 NUP205 MRPS12 SNRPE PSMC4 ILF2 COL1A2 DVL3 PSME2 HDAC1 TSTA3 ACLY	up	***
GO_TRANSFORMING_GROWTH_FACTOR_BETA_BINDING	0.0006507	0.0091215	0.4772708	-0.6193039	-2.084768	20	ACVRL1 ENG TGFBR3 TGFBR2 CD36 LTBP4 CD93 THBS1 NRROS LRRC32 LTBP1 LTBP3 CD109	down	**
GO_CELL_FATE_DETERMINATION	0.0002781	0.0045823	0.4984931	-0.5624553	-2.084000	29	GATA2 SOX17 CDC42 DSCAML1 TBX2 GATA3 MCL1 KLF4 CYP26B1 HES1 EBF2 IFRD1 GATA6 PTCH1	down	**
RUIZ_TNC_TARGETS_DN	0.0000001	0.0000060	0.6901325	0.4753989	2.083845	130	DKK1 TRIP13 FOXM1 HJURP CDC45 MCM10 FANCI PBK GINS1 E2F8 AURKB DIO2 CDC6 STC2 MCM4 MCM2 RAD54B TYMS CDC25A ORC1 DTL ZWINT SPDL1 MELK EXO1 AUNIP KIF2C MCM7 RRM2 RAD54L MCM3 EGFR CD24 DNAJC9 MAD2L1 PFKP RAD51AP1 DCTPP1 DSCC1 BLM NCAPG2 ASF1B CDK1 RFWD3 BIRC5 GMNN POLR3K E2F1 FEN1	up	***
GO_CILIUM_MOVEMENT	0.0000204	0.0005095	0.5756103	0.5499615	2.083756	52	STK36 SPAG17 DNAH3 KIF27 DNAI1 ARMC4 HYDIN WDR78 DPCD TEKT2 CCDC114 WDR66 NME5 GAS8 DNAH11 CCDC40 DRC1 KIAA0556 LRRC6 DNAH5 DNAH7 CCDC151 TEKT3 SPA17 DNAI2 TTLL6 RSPH4A CATSPER1 DNAH1 CELSR2 DNAAF1 TEKT1 WDR63 ROPN1L CCDC65 DNAH9 CABYR	up	***
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP	0.0000000	0.0000002	0.7749390	0.4598224	2.083722	175	FOXM1 HELLS FANCI NUP107 NEK2 IGF2BP3 CIB2 PBK KIF18B TTF2 TSPYL5 STIL ECT2 CDC6 TFDP2 MCM4 CCT6A ZWINT STAG3 CHAF1A MKI67 TP53BP1 BUB1 CCT5 AURKA CBX3 WDHD1 CHAF1B SOX4 YEATS2 SALL2 TOPBP1 CHEK1 ORC6 MAD2L1 PSMD4 BLM PABPN1 HDGF ATIC AAGAB LARP1 FEN1 SSX2IP NF1 SF3B3 ETFB PA2G4 IFT52 CHCHD3 DPP3 ALDH7A1 ARHGAP32 SPAG1 CCDC51 ZNF282 ENPP2 GALNT7 MARCKSL1 CDC7 CDC20 CENPM POP7 ASRGL1 PEX5 MCM6 PRMT1 CKAP2	up	***
MIR8074	0.0005360	0.0077822	0.4772708	-0.6730528	-2.082348	16	ZBTB34 ROCK2 FOXO1 ADO UBQLN1 NRBF2 RORA NRP2 EVI5 RMDN1 MAN1A1	down	**
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_UP	0.0000000	0.0000000	0.9101197	-0.3652471	-2.080672	312	HMOX1 OLR1 PDLIM2 PECAM1 CD55 MNDA LPXN GPR65 HSD17B6 FYN HSD17B11 LMO2 ST3GAL6 LDB2 QKI EML1 GIMAP6 TGFBR2 HEG1 ZEB2 ERG ANXA1 PTPRM SLC7A7 TACC1 ENTPD1 CLEC7A TMEM204 IFI30 GLS JAM3 RGCC CD93 AKT3 TFEC ZEB1 SRGN TUBB6 FLI1 EVI2B MSR1 TLE4 CASP1 PLAUR CPVL DAB2 GRK5 LY96 ABCC4 LAPTM5 PTPRC AXL RECK CCND2 TM6SF1 CD53 FCER1G ELK3 SMAD7 EVI2A INHBA DSE HLA-DQA1 FOXN3 EMP3 SGK1 CTSS C1QA HPGDS KCTD12 MAP4K4 TYROBP FERMT2 GLIPR1 ACKR3 IRF8 RASSF2 GFPT2 CELF2 PLCG2 LMCD1 PKD2 CD74 XYLT1 MME CPA3 TCF4 TGFB1I1 PLSCR4 COL15A1 CCR1 RGS2 CLEC2B GEM LDLRAD4 IL18 CPQ SPARCL1 MS4A4A MFAP5 IFFO1 S100A4 PARVA TIMP3 PTEN SAMSN1 ZFPM2 GIMAP4	down	***
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_DN	0.0000000	0.0000019	0.7195128	-0.4028752	-2.080420	152	EPAS1 CXCL3 SLPI STAC FCN1 HVCN1 GLIPR2 RAPGEF2 PID1 C5AR1 CDC42 MARCO NCF2 CD9 SLC11A1 PLA2G7 DNAJC3 SLC7A7 ENTPD1 CLEC7A RNASE1 DACH1 ANKRD29 IL10 SPNS3 KCNMA1 DAB2 PLBD1 ATP6V0D2 TM6SF1 IL7R HLA-DQA1 RPS6KA2 PDK4 SGK1 SLCO2B1 C1QA JUN ETS1 HK3 ELOVL7 CXCL5 CST7 KLF2 GJA4 SRSF6 CR1	down	***
GO_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	0.0000001	0.0000044	0.7049757	-0.4036103	-2.079834	144	ANGPT4 ACVRL1 SASH1 HMOX1 TEK PPARG GATA2 EMP2 BMPER BMPR2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 PTPRM ADAM17 HSPB1 FOXP1 GATA3 RGCC NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NUS1 ANXA3 PRCP NOTCH1 ETS1 RHOJ	down	***
YU_MYC_TARGETS_UP	0.0000231	0.0005655	0.5756103	0.5860187	2.079178	40	KIF20A CCNB1 RACGAP1 E2F8 ANLN ASPM PLK1 ECT2 CCNB2 DTL MKI67 BUB1 TOP2A AURKA DCTPP1 CKS1B CDK1 BIRC5 GMNN	up	***
JI_CARCINOGENESIS_BY_KRAS_AND_STK11_UP	0.0000147	0.0003884	0.5933255	0.8778302	2.078740	9	COL17A1 GPR87 TP63 KRT5 TFAP2A PKP1	up	***
GO_CHROMOSOME_CONDENSATION	0.0000193	0.0004884	0.5756103	0.6555859	2.078217	26	HMGA2 CCNB1 NCAPD2 TOP2A GPER1 CDCA5 NCAPG2 NUSAP1 CDK1 NCAPG AKAP8L BANF1 CHMP1A SMC2 NCAPD3 NCAPH ACIN1 DFFB	up	***
PUJANA_XPRSS_INT_NETWORK	0.0000001	0.0000035	0.7049757	0.4665946	2.077939	150	FOXM1 FANCI CHEK2 TIMELESS TTF2 NDC80 BRCA1 GINS1 GTSE1 POLE AURKB CENPA ESPL1 TFDP2 RBBP8 MCM4 MCM2 MYBL2 CCNF NCAPD2 ZWINT CASP2 HMMR CHAF1A MKI67 KNTC1 TOP2A AURKA CBX3 MPHOSPH9 PRKDC RAD54L LMNB1 TOPBP1 DNAJC9 MAD2L1 RAD51AP1 CAD BLM CNOT3 SKP2 CDKN2C CDK1 UNG DNA2 EZH2 DNMT1 SNRPA ANP32E KIF20B CDC7 CPSF4 CDC20 RPA1 MCM6 TBCA MCM5 AATF TCERG1 MSH2 CCNA2 PAXIP1 ZNF131 SMC2 TCF3 PAICS UBE2C PNN	up	***
LY_AGING_MIDDLE_DN	0.0000463	0.0010156	0.5573322	0.7586237	2.077515	15	FOXM1 CCNB1 CENPF PLK1 CENPA MYBL2 CCNF KIF23 KIF2C KIF11	up	**
GOLUB_ALL_VS_AML_DN	0.0003934	0.0060985	0.4984931	-0.6463173	-2.074968	18	CAT CD33 STOM SRGN MCL1 CST3 CFD CTSD ITGAX LGALS3 NFKBIA LYZ ZYX	down	**
GO_CHROMOSOME_CENTROMERIC_REGION	0.0000000	0.0000008	0.7477397	0.4606081	2.074550	160	PKHD1 HELLS HJURP BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TTK PLK1 NUF2 CDCA8 AURKB CENPA DYNC1I1 MIS18A NCAPD2 ZWINT CDT1 DCTN2 SPDL1 STAG3 BOD1 TP53BP1 KNTC1 BUB1 CENPL AURKA CBX3 REC8 TPR KIF2C MAD1L1 CENPW CDCA5 MAD2L1 CENPO SPC24 DSCC1 INCENP KNSTRN CBX5 CENPH BIRC5 NCAPG SPAG5 TRAPPC12 MTBP CBX1 CENPP RANGAP1 DNMT1 KIF22 HIRA CENPQ ESCO2 LRWD1 NUP85 CENPK CENPV CKAP5 CENPM DNMT3A DYNC1LI2 CENPT	up	***
REACTOME_SCAVENGING_OF_HEME_FROM_PLASMA	0.0000231	0.0005655	0.5756103	0.5474569	2.074266	52	HP IGLV3-27 IGKV1-17 HBA1 HBA2 IGKV3-15 IGKV3-11 IGKV1-16 IGKV4-1 HBB IGKV2D-28 APOL1 IGLV1-44 HPR IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGLV7-43 IGLV6-57 IGLV1-47 IGKV1D-12 IGHA1	up	***
GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP	0.0000000	0.0000007	0.7477397	0.4585673	2.073264	174	TRIP13 HS3ST1 RUVBL1 CDC45 NOXRED1 KIF18B TBRG4 BRCA1 DEPDC1B CDK4 IQGAP3 ASPM STIL ECT2 CCNB2 RBBP8 RAD54B TYMS SHMT2 NCAPD2 C2orf81 NME1 KIF23 MKI67 FANCA CCT5 CENPL KIF2C CENPW MRPL3 MRPL27 PASK MCM3 ZNHIT1 C7orf50 CBY1 CAD MNAT1 PSRC1 NUSAP1 ASF1B SLC39A11 POLE2 POLR3K DNA2 NEIL3 RECQL4 NPHP1 TUBG1 SNRPA LMNB2 GALNS DTYMK MYBBP1A GINS2 ANP32E AGPAT5 TSSK3 SGSM3 CNDP2 CDC20 CHCHD1 LRRC59 GPATCH4 BCL2L1 MCM5 NOC4L LANCL2 FFAR2 TSR1 NUP62 CCNA2 PRIM1 PRR11 SHCBP1 RFC5 HK2 RAD51 ARHGAP11A ZMYND19	up	***
GO_DNA_GEOMETRIC_CHANGE	0.0000015	0.0000537	0.6435518	0.4889582	2.071609	99	DDX11 DDX12P RUVBL1 CDC45 POLQ PIF1 GINS1 MCM4 MCM2 RAD54B MCM8 GINS4 RUVBL2 TOP2A SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 MNAT1 RECQL5 PARP1 SSBP1 NAV2 DNA2 RECQL4 CHTF18 GINS2 CHD5 RAD50 HMGA1 RPA1 MCM6 CHTF8 MCM5 ZRANB3 IGHMBP2 RTEL1 RFC5 RAD51 CHD3 XPC TP53	up	***
KEGG_DNA_REPLICATION	0.0000507	0.0010964	0.5573322	0.6098345	2.071084	33	PRIM2 POLE MCM4 MCM2 POLA2 POLD2 MCM7 MCM3 LIG1 SSBP1 POLE2 DNA2 FEN1 RNASEH2A POLD1 RPA1 MCM6 MCM5 PRIM1 RFC5	up	**
GO_NEGATIVE_REGULATION_OF_CELL_JUNCTION_ASSEMBLY	0.0005579	0.0080404	0.4772708	-0.5962622	-2.070930	22	ACVRL1 ACE DLC1 IL1B CORO1C APOD ROCK2 ROCK1 THBS1 FAM107A	down	**
MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP	0.0000562	0.0011868	0.5573322	0.7957137	2.070726	12	ANLN ASPM CENPA CCNB2 PRC1 CEP55 RRM2 NUSAP1 BIRC5 DIAPH3	up	**
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN	0.0000000	0.0000009	0.7477397	-0.3912209	-2.070547	169	CXCL3 EREG ASGR1 ADPRH GATA2 LY86 CORO1C ZCCHC2 ARL8B OTUD4 RBM7 HSPE1 PLA2G7 RRAGC MAP3K8 CAV2 SLC7A11 SERPINB9 PPP3CA ZFYVE16 TFRC MAP2K3 FAM49B SNIP1 CDS2 TLR4 ZBTB43 CD53 MARK3 NCOA1 MMP19 TDRD7 SAR1A CD48 NOTCH1 PPP1R15A GSTO1 DHX15 HSPA13 GRB2 ATP13A3 RNF24 CGGBP1 HIVEP2 FOXO3 ICAM2 PRKCG ITGA9 FPR2 CTNNAL1 SOD2 GABARAPL1 NPTN MFSD12 IL18RAP LRP12 NLRP3 SP100 HNRNPC C21orf91 DOCK4 EMC3 RNF13 SPHK1 SPSB1 C1QB CHIC2 ZFP36 MT1E IFIT5 CD69 WNT5A	down	***
GO_POSITIVE_REGULATION_OF_ALCOHOL_BIOSYNTHETIC_PROCESS	0.0003999	0.0061708	0.4984931	-0.6449348	-2.070530	18	IL1B LHCGR WNT4 P2RY1 ADCYAP1R1 ABCG1 PTAFR PTH1R HRH1	down	**
GSE3982_MAC_VS_TH1_UP	0.0000000	0.0000004	0.7614608	-0.3899539	-2.070001	178	SIDT2 SASH1 HMOX1 SWAP70 FCN1 CD101 ACE PHACTR1 DENND5A USP12 ATXN3 SLC6A12 ENG HSD17B11 PLEKHF2 RASAL2 NTM P2RY13 EOGT TMX4 RGCC SPRY2 EVI2B AGO4 PXDC1 KLF9 DRAM1 CEBPA SOCS5 SPAG9 ITGAX TLR4 GCA N4BP2L1 GNAQ EFR3A CLN8 TMEM9B SNAP23 VAT1 SNX29 TMEM251 SDHD OGFRL1 PPM1F SLC25A24 FOXO3 VAV3 IFNAR1 GALC APLP2 PLEKHO2 SERINC3 BMP2K SESN1 CEP170 CALHM2 RTN1 CHMP3 CES3 UBE2D1 SCPEP1 COMMD8 TMX2 MMD KIF1B CREG1 RABGEF1 PHYH ARHGEF17 CTSH MAPK1 CLOCK KCNJ1 TUBA1A CCNT2	down	***
GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP	0.0000000	0.0000004	0.7614608	-0.3899289	-2.069868	178	WEE1 ARHGAP31 PNPLA6 ACE CLDND1 FYN PDE1B PPP4R1 FLVCR2 TGFBR3 RFTN1 GGA2 ZEB2 SH2B3 PTPRM ENTPD1 TNIP3 LUZP1 TTYH2 CAMTA1 STOM RB1 SRGN MAP2K3 KIF1C AHNAK THBS1 MIR24-2 EPS15 LYAR KLRD1 PPP2R5C SH2D2A CRIM1 CNOT6L PI4K2A GLB1 TSPAN18 MYO1C PHACTR2 IL2RB OASL SEC14L1 ATP6V0B RAPGEF1 MPZL3 GPR183 GTDC1 TBX21 TIGIT CCR4 SAV1 AKIRIN2 ATXN1 GABARAPL1 RGS2 RXRA SYT11 IL18RAP CALHM2 NLRP3 RBMS3 AIM2 IQGAP1 PIEZO1 SLFN11	down	***
GO_DNA_INTEGRITY_CHECKPOINT	0.0000000	0.0000020	0.7195128	0.4679436	2.069462	141	HMGA2 CDC45 TICRR CHEK2 CCNB1 TIMELESS BRCA1 BRSK1 E2F8 GTSE1 PLK1 CDC6 TFDP2 ORC1 DTL CDT1 CDK5RAP3 CASP2 TP53BP1 RHNO1 TOP2A AURKA EME1 ATR CLSPN PRKDC CDC25C SOX4 EME2 TOPBP1 CHEK1 NEK11 MDM2 BRIP1 BLM PML CNOT3 CDK1 RFWD3 E2F1 DNA2 CNOT11 CEP63 INTS7 CNOT2 RAD9A FBXO4 FZR1	up	***
GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN	0.0000000	0.0000006	0.7477397	0.4528484	2.069339	182	TRIP13 FOXM1 KIF20A RUVBL1 CDC45 MCM10 FANCI CCNB1 PBK DDIT4 TSFM DEPDC1 PHGDH CDK4 RACGAP1 ASPM AURKB PTTG1 ALDH18A1 ESPL1 CDC6 CCNB2 RBBP8 SMPDL3A SPATS2 XPNPEP1 ORC1 DTL NCAPD2 SPDL1 NME1 MELK KIF23 PAQR4 MKI67 KIF15 LGMN CCT5 MCM7 RAD54L KIF11 AIMP2 MAD2L1 RAD51AP1 DCTPP1 IPO9 NCAPG2 CBX5 MCTP2 RFWD3 NCAPG FEN1 EZH2 SPAG5 FGFR1OP ITPR3 DNMT1 DPP3 TUBG1 DLGAP5 TACC3 TUBB2A GINS2 ANP32E CLTA POLD1 CDC20 HMGA1 ZNF160 LANCL2 SRSF1 HMCES LRRK1 NT5DC2 AP2S1 RER1 SMARCA4 BANF1 SHCBP1 LPIN1 ATOX1 RARRES1 PGAM1 TNS3 SMC2 CENPE SEPHS1 PPIA UBE2C ADCK2 PLIN3	up	***
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_2_PRODUCTION	0.0002949	0.0048135	0.4984931	-0.5539790	-2.068897	30	IL1A IL1B ANXA1 CLEC7A TRAF6 SPTBN1 PDE4D PTPRC CD80 CD83 MALT1 CD86 PDE4B RIPK2	down	**
GO_DNA_REPLICATION_CHECKPOINT	0.0000426	0.0009455	0.5573322	0.7392760	2.068809	16	CDC45 TICRR TIMELESS CDC6 ORC1 CDT1 CLSPN TOPBP1 DNA2 RAD9A	up	***
GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_UP	0.0000000	0.0000006	0.7477397	0.4581169	2.067756	167	STYK1 KIF20A C21orf58 PSPH CMTM1 PLK1 CCNF COQ3 WDR90 RANBP1 FBXO43 KNTC1 TMEM177 E2F2 POC1A C1RL GPSM2 CDC25C ZNHIT1 CENPO RAD51AP1 SPC24 CAD INPP4B CKLF INCENP MRPL37 E2F1 REEP6 SDR42E1 METTL3 SAPCD2 LAPTM4B FGFR1OP CHCHD2 NET1 SNRNP25 IFI27L2 TSPAN17 GSS SNRPA DHODH DTYMK C1orf131 ESCO2 GINS2 KIF20B ASNS FBXO44 TCEA2 VPS25 STOML2 WDR34 MGME1 PPCDC ROMO1 NOC4L GGT5 LSM4 CHRNA5 RRP36 FARSB AIFM2 PAXIP1 WDR76 SNUPN ARHGEF39 LIF CENPE BCAT2 E2F7 C4orf46 CALU MLLT11 EIF2D DRG1 MRPS16 ZDHHC13 MRPL12 DSN1 COMTD1 FAM111B	up	***
MCLACHLAN_DENTAL_CARIES_UP	0.0000000	0.0000001	0.7881868	-0.3782405	-2.067467	210	SLPI ACP5 FCN1 PECAM1 CD55 SFRP4 IL1B MNDA CD44 C5AR1 BCL2A1 NCF2 IL1RN TRIB1 PLA2G7 MAN2B1 CLEC7A IFI30 ANPEP RNASE1 SLC7A11 MS4A1 LCP1 CD93 SRGN MCL1 APOC1 CD37 EVI2B MSR1 CFD PLAUR CPVL LY96 FAM49B CCL3 LAPTM5 PTPRC CD53 FCER1G ALOX5AP PLEK EVI2A INHBA IL7R HLA-DQA1 MAFF ARHGDIB HCK HCAR3 IL6 CTSS SOCS3 AQP3 CD48 C1QA RAB31 RAC2 TYROBP TREM1 PTGER4 IRF8 CXCL5 IGKV3-20 ACSL1 CD74 CD1D COL15A1 SOD2 IGHV3-23 CCR1 KYNU RGS2 CLEC2B IGKV1D-39 ICAM1 TNFAIP8 CEBPD MS4A4A CXCR4 CTSC SAMSN1 MT2A LYZ REEP1 CYBA CSF2RB C1QB CTSH	down	***
WONG_ENDMETRIUM_CANCER_UP	0.0000413	0.0009209	0.5573322	0.6906167	2.067069	21	KIF1A LTF SAA2 HP TFAP2A S100A2 TFF3 LCN2 FOXA1 SERPINA3	up	***
GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_DN	0.0000000	0.0000007	0.7477397	-0.3890937	-2.066830	179	RAB11FIP1 NLRC4 KMO OLR1 OSBPL11 SECISBP2L GAPT IL1B TMEM170B DNAJB14 PBX3 CSGALNACT2 ADIPOR1 C1orf162 PPP3CA MPHOSPH6 TCF7L2 FBXL5 HMGN1 EFCAB14 TAPT1 MTMR6 PRKD3 PLEKHM3 THBS1 TM6SF1 ZMPSTE24 PINK1 SLC6A6 CNOT6L NCOA1 HAUS1 GZF1 FLT1 CDC40 GABARAPL2 HECA C2CD2 DESI2 MED30 DDX17 CARD8 TMEM251 UBAC2 PTGER2 ATP13A3 TRAK2 ZCCHC9 ZBED5 GAS2L3 PKD2 ATG2B ZBTB1 MILR1 KYNU SERINC3 CCNH PCM1 CPQ CEP170 MEGF9 CUL3 PAIP2 CAMSAP2 SPATA5L1 SPOPL HAT1 SLC19A2 MAPK1 ITGB1 FBXW2 XPO7 UBE3A HMGB1 PAXBP1 KLHL9 SRP14 SDCCAG8 DOCK5	down	***
GO_NEGATIVE_REGULATION_OF_DNA_REPAIR	0.0000631	0.0013153	0.5384341	0.6673990	2.066612	24	HMGA2 PARPBP POLQ MAGEF1 TP53BP1 AUNIP HELB RECQL5 MAD2L2 UBQLN4 TWIST1	up	**
REACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC	0.0000025	0.0000841	0.6272567	0.4960321	2.065733	89	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 COPB2 KIF27 KIF23 KIF15 COPG2 COPG1 KIF3B KIF2C KIF11 KDELR2 KIF3C TMED3 NSF KIF5A STX18 KIF19 KIF2A TUBB2A TUBA3D KIF22 ARF5 TUBA8 KIF21A KIF20B KLC2 KLC4 KDELR3 GBF1 KIF21B COPZ1 ARFGAP1 TUBA4B COPA TMED9 CENPE COPZ2 TUBA1C	up	***
CUI_TCF21_TARGETS_2_UP	0.0000000	0.0000000	0.9545416	0.4256532	2.065697	371	HMGA2 GRIP1 MEX3A HELLS EYA1 HJURP KCNK5 CDC45 TIMELESS UBE2T HOXB6 WFDC2 MPP6 TBRG4 PHGDH CDCA7 METTL1 IQGAP3 NIPSNAP1 LYPD6B ASPM NUF2 CDCA8 CENPA PTTG1 ALDH18A1 ESPL1 SLC4A3 TPX2 CCNB2 UHRF1 LSR TYMS DTL CLCN2 CDT1 NME1 RANBP1 BZW2 HMMR KNTC1 PAFAH1B3 POLD2 VASH2 TMEM132A MCM7 CDCA5 SBK1 MCM3 PLTP CHAF1B LMNB1 CDC25C EMG1 SALL2 MDK RBP1 BRI3BP SPINT1 DNAJC9 SOX11 MSI1 DCTPP1 XRCC1 PIH1D1 SPC24 DSCC1 CAD RAD18 BLM CLDN9 HSPBP1 SKP2 BMP5 INCENP THOP1 KNSTRN DCLK1 CKS1B CBX5 KRT18 CDK1 ARHGAP39 SERTAD4 PLCH1 C1orf112 ATIC ANKRD54 TCTN2 PSAT1 COL3A1 CCDC88C ATAD3A LRRC56 VPS72 TMEM231 CPXM1 SRD5A1 PA2G4 ZNF692 EVC2 NPHP1 COL1A1 RGS17 DCAKD TACC3 RBFOX3 FNDC4 MNS1 KIF22 MORN2 TK1 DTYMK NFATC4 COLEC11 PCDH9 PRMT7 POLD1 ESR1 CNDP2 CENPK PTN CENPV TIMM13 CKAP5 WDR34 KRT8 COMP CELF4 MCM5 NOC4L VCAM1 EXOSC5 LSM4 NT5DC2 PATZ1 PYCR1 CFH MMP16 CCNA2 RCN3 PRIM1 BANF1 DNAH1 RAD51 NLGN2 FMOD MRPL9 SNRNP70 MXD3 CLEC11A CAMSAP3 APEX1 SYNE2 MRPS27 UBE2C FAXC FAM185A NDUFB7 PPP1R14B TRAPPC6A RANGRF NCAPH CD38 PRKAR1B AKR7A2 ISLR UNC119	up	***
GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	0.0000000	0.0000000	0.8870750	0.4345429	2.065302	286	DDX11 KCNK5 TMEM86B NPIPB3 MSTO1 GPC2 EIF3B XPO5 INTS1 SPPL2B CUL9 QTRT1 CUL7 POLM FANCA SEMA6C TRRAP SETDB1 SLC4A11 PHKG2 CDC42EP1 TMEM63A HSF4 FBXL19 SNAPC4 SYMPK LTB4R CNOT3 ERCC2 C7orf26 PABPN1 MCTP2 PICK1 TNK2 ANKRD54 SUN1 ZMIZ2 NPM3 KCTD13 SMG9 CMTR1 AP5Z1 DHX33 LARP1 DPH7 TNPO2 RNF207 ATAD3A UQCC2 STK11 ZNF692 RANGAP1 GIGYF1 CDK3 DCLRE1C SMG5 TRMU MTOR PUS1 ZNF133 HIRA IQCG COPS7B HIP1R ACAD10 SGSM3 FBXO44 RBM33 ZBTB7B LSM14B ABCC10 EPN1 L3MBTL2 CLASRP ZNF202 SRRT ABCA7 MYPOP USP21 HHLA3 LRCH4 PIP5K1A NEURL4 RTKN RCC1 SH3BP5L TCHP U2AF2 NUP62 ZNF580 SPON2 CAPN15 ENGASE SMARCA4 ABCF3 MRPS25 CSNK1G2 R3HDM4 PPP6R2 ZMYND19 SNRNP70 LLGL1 UBAP2L MAPK8IP3 TCF3 ZNF793 SRCAP SBNO2 LEMD2 RANBP3 TMEM201 SCAF1 MAP2K2 SETD5 FBXL18 ANKRD13D ACIN1 GRIP2 DAZAP1 PDXP SETD1A ZNF316 SEC31B TEAD3 SPHK2 CRYGS FURIN REXO1 ZNF598 TMEM259 HDAC10 DEPDC5 APBA3 TNPO3 TRABD GGA1 URB2 ZNF638 SAFB2 ARMC6 CACTIN CNTROB ZNF524 TTC13 KMT2D EVI5L NUP214 SUGP2 SLC12A9 ZNF473 PPM1G GRAMD4 NSUN5P1 KHSRP PHF21A SLC39A3 CIC TTC17 ATF5 SH3BP1 LIMK2 DAGLB AMPD2 GBA2 ATXN2L FBXO46 SMARCD1 DRG2 TARDBP LPAR2 HDAC7 TECPR1 MBD3 ACAP1 ZNF444 AGRN AP5S1 KDM4A MIIP DMWD SEC61A2 ZNF646 SMG7	up	***
GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_DN	0.0000000	0.0000005	0.7614608	-0.3890313	-2.065103	178	ABHD5 TSPAN4 DENND5A SNX10 CLDND1 HSD17B11 CD44 CTSW SAMHD1 ST3GAL6 MYADM AQP9 BCL2A1 CD22 ABCB1 ANXA1 ASAH1 MAP3K8 PBX3 LITAF PRSS12 MS4A1 SERPINB9 GATA3 IL18R1 CRTAM CYP4V2 PPP3CC AHNAK CASP1 OSTF1 SOCS2 PLBD1 ITGAX ID2 CCL4 RECK PLEKHB2 PRF1 EVI2A DSTN N4BP1 PLCD1 MAPRE2 CD160 GABARAPL2 SLC35E4 LIMD1 KCTD12 GSTO1 STX7 EEA1 DAPK2 IRF8 SERPINB6 CST7 KRTCAP2 CHPT1 LGALS3 FCGRT DBNDD2 RNF138 IL18RAP SEMA4A CYB5R4 TRAF1 S100A4 PALD1 KLRK1 CHCHD7 MCOLN2 CCND3	down	***
WAMUNYOKOLI_OVARIAN_CANCER_GRADES_1_2_UP	0.0000001	0.0000048	0.7049757	0.4738882	2.064807	125	TSPAN8 UNC5CL GMDS ELOVL6 FRK TOX3 GALNT4 ECT2 SFXN1 PLS1 ASPHD2 BZW2 GOLPH3 MAP7 SYTL2 GFPT1 MYO10 CPD CD24 BRI3BP KDELR2 PERP RASSF6 SLC39A11 ESRP1 ABHD17C GNPNAT1 ETFB OCIAD2 PBLD NET1 EDEM3 LLGL2 DOK4 GALNT3 SGSM3 TMEM30B GALNT7 ARHGAP12 ACBD5 TSTA3 ERBB3 GPATCH4 CHMP4C ABCC3 SLC35A3 PDIA4 STK39 EPCAM DDAH1 MLLT6 LRRC8B NME7 EPHB4 MUC1 NQO1 PLAC8 PDZD8 ABHD2 MECOM KIAA1841 KCNK1 ABCD3 ELL3 TMEM181	up	***
RB_P107_DN.V1_UP	0.0000004	0.0000170	0.6749629	0.4784325	2.063820	118	CDC45 PRIM2 E2F8 GTSE1 POLE MCM2 PRC1 CCNF COX6B2 GINS4 NCAPD2 WDR90 RPL39L PAQR4 FANCA SNCG MCM7 RRM2 WDHD1 CHAF1B LIG1 DNAJC9 ORC6 MAD2L1 IPO9 SAMD10 PML NAA40 EDN2 INCENP ASF1B POLE2 CENPH GMNN E2F1 DNA2 FEN1 CCNE1 COL1A1 TUBG1 COL1A2 POLD1 CENPK RPA1 MCM6 MCM5 HMCES TMEM45B CDH11 PRIM1 RFC5 BLVRB	up	***
GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_UP	0.0000000	0.0000005	0.7477397	-0.3887599	-2.063663	178	MIR22HG SIK1 EGR2 FCER1A BCL2A1 GIMAP6 TRIB1 IER2 CCNL1 CD5 RILP PPP1R15B SDE2 MAP3K8 RNF125 GATA3 NR4A1 FAM122A CES1 SRGN BTG3 FBXO8 EVI2B CSRNP1 ITPRIP CASKIN2 COQ10B ID3 STK17B PER2 NKIRAS1 ATF3 CCL4 PNRC1 PER1 DUSP1 SH2D2A MAFF SRF NRROS ETF1 VAMP3 SLC25A25 ETV3 ARL5B PLK3 JUNB RHOG PPP1R15A MALT1 FOS FOSB CCR4 TGIF1 CD6 DUSP5 MAGOH IST1 ELF5 GEM SELPLG SFT2D1 LRP12 TOB2 MEX3C TRAF1 ISCU GPR171 SAMSN1 NABP1 ATF4 EGR1 DUSP6 ATP11B NR4A2 ZFP36 YRDC CD69 DPF3 SGIP1 TRIM13 TSC22D2 RAB1A FASTKD5 NR4A3 NFKBIZ KBTBD2 DUSP2	down	***
FOURNIER_ACINAR_DEVELOPMENT_LATE_2	0.0000000	0.0000000	0.8390889	0.4367703	2.062764	257	TRIP13 DDX11 FOXM1 HJURP CDC45 FANCI ELOVL6 NUP107 DROSHA TIMELESS POLQ PAGR1 NDC80 DEPDC1 TTK GINS1 RACGAP1 ASPM PLK1 CENPA PTTG1 CDC6 MCM4 MCM2 CDC25A FERMT1 PRC1 CCNF DTL SRPK1 ZWINT CCT2 RANBP1 MELK CHAF1A LAMC2 GFPT1 IGF2BP2 EEF1E1 AURKA SAE1 KIF2C MCM7 RRM2 TTLL12 PRKDC MRPL3 MCM3 KDELR2 TXNDC5 DNAJC9 CAD BLM FLNB SKP2 CKS1B NCAPG2 NUSAP1 ANAPC5 CDK1 UCK2 RFWD3 BIRC5 MRPL17 FEN1 NUP205 METTL3 SF3B3 TTI1 RNASEH2A TUBG1 GINS2 ANP32E NOC2L NUP85 CDC7 NIF3L1 ETV4 GEMIN6 SUPT16H CKAP5 POP7 MCM6 PLEK2 RAI14 CDCP1 RCC1 PHC2 STK39 NT5DC2 ALG8 PRMT5 PMS1 FAM3C SMARCA4	up	***
GO_OLIGOSACCHARIDE_CATABOLIC_PROCESS	0.0007805	0.0104932	0.4772708	-0.7872938	-2.062727	9	MANBA MAN2B1 GM2A TREH CTBS HEXB	down	*
GCM_PTPRD	0.0000706	0.0014401	0.5384341	-0.4845711	-2.061397	52	CCDC88A KIAA1109 PLEKHA1 ACER3 ZEB2 DNAJB14 TTL NLK SPIRE1 TTYH2 ABHD6 MOAP1 PEG3 DOCK9 BACE1 GZF1 MAP4K4 FRYL NAA30 CLASP2 ARPP19 SIK3 MEGF9 ULK2 KIF1B	down	**
GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_DN	0.0000000	0.0000010	0.7337620	0.4556928	2.060267	174	CEP89 CDC45 MCM10 ELOVL6 NEK2 PSPH BRCA1 TTK RACGAP1 E2F8 ANLN CDCA8 AURKB ECT2 CDC6 SFXN1 CCNB2 UHRF1 MCM2 MYBL2 PRC1 ORC1 DTL CDT1 TAMM41 RANBP1 EXO1 NUDT1 CISD1 KIF23 TOP2A AURKA MCM7 RRM2 RGL1 CDCA5 PDCD5 MRPL27 KIF11 CDC25C RBP1 KDELR2 CHEK1 ORC6 MAD2L1 AHCY BLM CKS1B DRC1 NUSAP1 CBX5 ASF1B CDK1 BIRC5 POLR3K E2F1 SSX2IP DIAPH3 KIF22 ZNF239 SAP30 CENPK PSMB3 CDC20 MRPL41 CKAP2 ROMO1 SURF2 NFE2 MRPL51 AP2S1 RPS26 CCNA2 RFC5 HK2 RAD51 SEC13 PGAM1 UQCRQ CENPE	up	***
GO_NEGATIVE_REGULATION_OF_RECEPTOR_SIGNALING_PATHWAY_VIA_JAK_STAT	0.0008150	0.0108258	0.4772708	-0.6118877	-2.059803	20	DAB1 CAV1 MIR146A SH2B3 ADIPOR1 SOCS2 PPP2CA SOCS3	down	*
REACTOME_DAP12_INTERACTIONS	0.0001917	0.0033237	0.5188481	-0.5448982	-2.059674	33	SIRPB1 FYN CD300E KLRD1 CD300LB TYROBP TREM1 PIK3R1 GRB2 SIGLEC15 PLCG2 KLRC2 SIGLEC14 VAV3 LAT KLRK1	down	**
INAMURA_LUNG_CANCER_SCC_DN	0.0005448	0.0078823	0.4772708	-0.7356237	-2.059564	12	CAV1 MCL1 ADARB1 ADAMTS8 RASL12 VWF PHACTR2 ABCA8 ADAMTSL3	down	**
KIM_WT1_TARGETS_8HR_UP	0.0000000	0.0000019	0.7195128	-0.3931036	-2.059377	157	EREG SWAP70 CSDC2 BAIAP2 FOSL1 QKI BMPR2 TBC1D2 BCL2A1 RGPD5 TRIB1 ATP2B1 HBEGF NLK KLF10 PPP3CA SIRPA ZMYM6 TNS1 BTG3 RAB14 ZMIZ1 MAP2K3 PLAUR PEG3 DAB2 ARC MAFF AFF1 SERTAD2 ID4 AREG RYBP SNAP23 JUN SH3BP5 HSPA1B JUNB PODXL GFPT2 RHOQ SRSF6 PEA15 TGFB1I1 PIM1 GEM RLF SRP72 HSP90AA1 TIMP3 DUSP7 FGFR1 NAA15 GRB10 DNAJB5 SPHK1 SERPINE1 HIPK1 FHOD1 ZYX DNAJB4 DNAJB1 PIAS2 WWTR1 CSPG4 TPST2 PLEKHO1 EMP1 CBFB IVNS1ABP ST3GAL1 ADAM19 SON	down	***
MORI_PLASMA_CELL_DN	0.0001827	0.0031786	0.5188481	-0.5361338	-2.059307	35	LMO2 CD22 MS4A1 LAPTM5 COTL1 ELK3 CALM2 LRCH1 CD83 REL PANK2 PIK3AP1 BMP2K SPIB TSPY26P MICAL1 GPR137B TNFRSF13C GPATCH2L	down	**
GO_CELL_CYCLE_DNA_REPLICATION	0.0000222	0.0005476	0.5756103	0.5310636	2.059185	58	CDC45 CHEK2 PRIM2 GINS1 E2F8 DBF4B POLE MCM4 MCM2 CDT1 POLA2 POLD2 MCM7 MCM3 LIG1 POLE2 GMNN DNA2 FEN1 POLD1 ATAD5 CDC7 RPA1 MCM6 MCM5 PRIM1 RTEL1 RFC5 NUGGC RAD51 BCL6 E2F7 WIZ	up	***
GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN	0.0000000	0.0000011	0.7337620	0.4565275	2.059040	168	TRIP13 MDM1 CDC45 GPT2 BUB1B PDCD2L TTF2 PRIM2 ALDH1L1 DNMT3B TTC26 CEP70 TPX2 TFDP2 SLC4A4 PRC1 INTS1 MELK RPAP1 KNTC1 IGF2BP2 CARD10 KIF2C E2F2 CLSPN WDHD1 PYCR2 LIG1 ORC6 MAD2L1 CKAP2L BRIP1 BLM FADS2 KNSTRN EFCAB11 BIRC5 GNB1L C1orf112 GMNN VANGL2 L2HGDH CENPP FOCAD RAPGEF5 DGCR6 KCNH3 CCNE1 DCLRE1C ALDH7A1 NMRAL1 LMNB2 MNS1 ZNF239 EDARADD KIF20B TRIM32 CD27-AS1 C15orf41 CEP128 PLEKHB1 SASS6 PTER CCDC30 ARVCF MYO5C HIBADH BSN NFE2 HTRA3 PRIM1 PRR11 TTC12 SHCBP1	up	***
GSE34515_CD16_POS_MONOCYTE_VS_DC_DN	0.0000000	0.0000008	0.7477397	-0.3868618	-2.058936	177	SIDT2 SASH1 PDLIM2 DENND5A CPEB2 THBD BMP2 LMO2 CCRL2 NEDD4L C5AR1 S1PR1 ANAPC15 FUCA1 TGFBR2 ZBTB4 MCTP1 MAP3K8 RNF144B KLF6 ADIPOR1 CD93 CLK1 CYP4V2 MCL1 AGO4 PPT1 TCP11L2 PLEKHM3 CD302 ARAP3 ALOX5AP N4BP2L1 IL7R FAM76B RASGEF1B NCKAP1L NINJ1 MYLIP RNF149 NOTCH1 IRF8 PSTPIP2 WDFY4 PLCG2 RRAS PIK3AP1 ZC3H12D RELL1 BRI3 NBEAL1 KANSL2 DBNDD2 BNIP3L CXCR4 ARHGAP18 FNIP2 FNBP1 HTRA2 ITGAL ZFYVE1 EYA3 CCNT2 PIK3CG GPR137B STX16 EP300 PAXBP1 ATP8A1	down	***
GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN	0.0000001	0.0000028	0.7195128	0.4574695	2.058695	162	TRIP13 FOXM1 PARPBP GPT2 BUB1B CCNB1 CENPF PBK CCDC113 TTK GINS1 E2F8 KIF14 NUF2 PTTG1 CDC6 TPX2 CCNB2 SPATS2 MCM2 TYMS GLDC DTL ZWINT MYL6B CLPTM1L MELK HMMR CEP55 SDHA MKI67 EMC9 KIF15 BUB1 AURKA IGLV1-44 RRM2 KIF11 IGKV1-5 CHEK1 ANKRD16 NUSAP1 CDK1 DMGDH NCAPG SPAG5 TUBG1 DLGAP5 IGHM FKBP14 CEP128 DENND5B CDC20 EFHC1 CLINT1 CREB3L2 NT5DC2 SLC2A5 DCPS SHCBP1 CCDC167 SMC2 MTHFD1 IGLV3-19 SRPRB CBWD1 ZC3HAV1L BFSP2 CD38 RTN4IP1 C11orf80 MRPL12 DSN1 FBXO5	up	***
GO_BASE_EXCISION_REPAIR	0.0000409	0.0009162	0.5573322	0.5745847	2.058056	41	HMGA2 POLQ POLE LIG3 SMUG1 POLM LIG1 XRCC1 PRMT6 UNG DNA2 NEIL3 FEN1 POLL MBD4 POLD1 POLB HMGA1 RPA1 SIRT6 MPG TP53 NEIL1 APEX1 PARP2	up	***
GSE15767_MED_VS_SCS_MAC_LN_UP	0.0000000	0.0000003	0.7614608	-0.3899932	-2.057677	171	ACP5 ACVRL1 SASH1 OSBPL11 TMEM150B PID1 LY86 LMO2 C5AR1 CLEC10A FXYD2 MEF2A GAS6 EPB41L3 FAM49A ZEB2 ERG SLC7A7 ASAH1 CLEC7A ANXA5 HLX LRP4 MSR1 AGO4 MTMR6 PTPRO THBS1 PLBD1 SELL TLR4 FCER1G DSE DSTN HLA-DQA1 CLN8 NCKAP1L NINJ1 PKIG MYO1C RAB31 INMT ATP6V0B IRF8 SELENBP1 HOMER1 RALB MORF4L1 FOS SIGLEC1 TREX1 CPA3 NIPA2 FPR2 CPQ B3GALNT1 HSP90AA1 DACT2 EPHA4 ALDH2 ARPC5 TMCC3 NRP2 DOCK4 CREG1 FCRL1 PHOSPHO1 CSF2RB CAPZB MYH10 NCF1 HLA-DRB1 MFSD1 FCGR3A SKAP2 STARD5 KLHL9 BFSP1 CTF1 CLVS1 FNIP1 DUSP22 LRP1 METRNL	down	***
GO_CHROMOSOME_SEGREGATION	0.0000000	0.0000000	0.8266573	0.4355194	2.057381	259	TRIP13 DDX11 SPICE1 DDX12P HJURP STAG3L2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 BRCA1 TTK CDCA2 RACGAP1 KIF14 MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ECT2 ESPL1 CDC6 PRC1 MIS18A SRPK1 NCAPD2 ZWINT CDT1 SPDL1 TOP3B KIF23 STAG3 MKI67 BOD1 BUB1 TOP2A MAP10 EME1 REC8 SYCP2 TPR KIF2C MAD1L1 CENPW CDCA5 FANCD2 HORMAD1 EME2 NEK11 MAD2L1 DSCC1 BRIP1 RAD18 ERCC2 RECQL5 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 BIRC5 SUN1 DIS3L2 NCAPG FEN1 SPAG5 TRAPPC12 MAD2L2 KLHL22 KPNB1 CCNE1 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA CENPQ AKAP8L ESCO2 ANAPC1 SLX4 ANKRD31 CENPK STAG3L4 MEI1 CDC20 TUBG2 CHMP4C FANCM CDK5RAP2 CHTF8 CENPT	up	***
GO_MITOCHONDRIAL_TRANSLATION	0.0000002	0.0000105	0.6749629	0.4723740	2.056182	124	TSFM MRPL46 SHMT2 MRPS35 UQCC1 AARS2 MRPL15 LARS2 ERAL1 MRPL3 MRPL27 TARS2 SARS2 MRPS11 MRPS30 MTG1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 UQCC2 COA3 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 YARS2 IARS2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 CDK5RAP1 GADD45GIP1 MTIF3 MRPL9 MRPL21 AURKAIP1 EARS2 MRPS27 MRPL20 MRPL48 MRPS26 TRUB2 MTG2 RPUSD3 MRPS16 MRPL12 MRPL43 FASTKD3 MRPL2	up	***
GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP	0.0000001	0.0000050	0.7049757	-0.3986714	-2.056158	148	SIRPB1 LPIN2 ABHD5 CD101 DLC1 ADTRP LPXN PTPRE PPP4R1 RASAL2 SLC39A8 S1PR1 KCNN3 IL1RN NFATC3 CD8A HBEGF ADAM17 CRTAM CD58 EVI2B IL10 CASP1 USP2 CCL3 SELL CCL4 WASF3 ELK3 EVI2A TP53BP2 RABGGTB CD8B RBPJ FLT1 JUN LRCH1 GSTO1 IFRD1 GPR183 LSM1 CXCL5 RHOQ BCAS2 TCF4 STRN TEX30 KHDRBS1	down	***
KANG_FLUOROURACIL_RESISTANCE_DN	0.0000540	0.0011499	0.5573322	0.7342826	2.054836	16	SLC2A1 DDIT4 LAMC2 ITGB4 NFYA MST1R BACE2 FLNB	up	**
GO_AXONEMAL_DYNEIN_COMPLEX_ASSEMBLY	0.0000427	0.0009463	0.5573322	0.6689117	2.054709	23	DNAI1 ARMC4 TEKT2 CCDC114 DNAH8 DNAAF3 CCDC40 DRC1 LRRC6 DNAH5 DNAH7 CCDC151 SPAG1 DNAI2 DNAH1 ZMYND10 DNAAF1 WDR63 CCDC65 DNAL1	up	***
GO_KINESIN_COMPLEX	0.0000572	0.0012068	0.5573322	0.5471254	2.054562	49	KIF1A KIF12 KLC3 KIF20A KIF18B KIF14 KIF27 KIF23 KIF15 KIF3B KIF2C KIF11 KIF3C KIF5A KIF19 KIF2A KIF7 KIF22 KIF21A KIF20B KLC2 KLC4 KIF21B	up	**
PID_ALK1_PATHWAY	0.0007624	0.0102873	0.4772708	-0.5915765	-2.054387	23	ACVRL1 ENG CAV1 BMPR2 TGFBR2 SMAD7 INHBA TGFB1 FKBP1A ARRB2 SMAD4 MAPK1	down	*
GNF2_SERPINB5	0.0000777	0.0015648	0.5384341	0.6633524	2.054082	24	COL17A1 GPR87 TP63 KRT5 S100A2 FERMT1 LAMC2 PERP GJB3 CDH3 KRT19 AHNAK2 PTHLH FGFBP1 KRT17	up	**
REACTOME_SIGNALING_BY_BMP	0.0007885	0.0105722	0.4772708	-0.5912035	-2.053091	23	SMAD6 ACVRL1 GREM2 BMP2 BMPR2 ZFYVE16 UBE2D3 SMAD7	down	*
GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_DN	0.0000001	0.0000028	0.7195128	-0.3909454	-2.051855	165	CLIC3 PHACTR1 LYVE1 GPR65 PTPRB FYN RGS9 CTSW GFOD1 TGFBR3 ABCB1 CD8A GGA2 ZEB2 CACNA2D2 C1orf21 BZW1 MAP3K8 LITAF ADRB2 CRTAM PDGFA PTPN12 YBX3 MVB12B ITPK1 RIT1 ID2 CCL4 PRF1 PLEK KLRD1 MATK SH2D2A CRIM1 CD8B PKIG CD160 IL2RB GTDC1 HOMER1 TNFRSF9 TBX21 CASZ1 CST7 CDK14 PLCG2 RHOQ UBB RUNX3 NKG7 VAV3 TCF4 PDLIM1 CLCN6 SPARCL1 SEMA4A SPIB CD19 PDE4A KLRK1 ITCH FEZ1 SPHK1 KLRF1	down	***
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_BIOSYNTHETIC_PROCESS	0.0004829	0.0071444	0.4984931	-0.7043571	-2.051811	13	EREG IL1B CLEC7A TRAF6 PTAFR TYROBP CD74	down	**
REACTOME_CHROMOSOME_MAINTENANCE	0.0000089	0.0002539	0.5933255	0.5274178	2.051405	59	HJURP RUVBL1 PRIM2 PIF1 CENPA MIS18A RUVBL2 CENPL POLA2 POLD2 CENPW LIG1 CENPO DSCC1 BLM CENPH DNA2 FEN1 CENPP CHTF18 CENPQ POLD1 CENPK CENPM RPA1 CHTF8 CENPT PRIM1 RTEL1 RFC5	up	***
GO_VENTRICULAR_TRABECULA_MYOCARDIUM_MORPHOGENESIS	0.0007781	0.0104653	0.4772708	-0.6909372	-2.051394	14	CCM2L ENG HEG1 TGFB2 RBPJ NOTCH1	down	*
GO_CILIARY_PLASM	0.0000060	0.0001809	0.6105269	0.4893220	2.050225	92	DNAH2 RPGRIP1L CENPF SPAG17 DNAH3 AK8 DNAI1 ARMC4 BBS1 SPAG16 HYDIN WDR78 CCDC114 DCDC2 WDR66 DNAH8 IFT172 GAS8 DNAH11 TULP3 CCDC40 DRC1 KIF19 SPAG6 LCA5 DNAH5 SPEF1 BBS5 DNAH7 MNS1 CCDC151 TRAF3IP1 DNAJB13 WDR34 TTLL3 EFHC1 RPGRIP1 DNAI2 WDR35 DYNC2H1 NEK4 RSPH4A	up	***
chr8p21	0.0000322	0.0007476	0.5573322	-0.4411177	-2.049897	77	PEBP4 PDLIM2 PHYHIP DPYSL2 KCTD9 LPL C8orf58 SCARA3 BMP1 PPP2R2A SLC25A37 ATP6V1B2 PPP3CC SORBS3 SDAD1P1 GNRH1 EBF2 HMBOX1 PNMA2 RHOBTB2 ADRA1A ENTPD4 TNFRSF10B SFTPC DOK2 SCARA5 BNIP3L GULOP TNFRSF10D INTS10	down	***
GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION	0.0000465	0.0010187	0.5573322	0.5777500	2.049841	40	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 MAD2L2 KLHL22	up	**
GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_DN	0.0000000	0.0000008	0.7477397	-0.3859426	-2.048707	178	EREG OSBPL11 U2AF1 CYP27A1 LPXN CLDND1 EGR2 RTN3 SLC11A1 SH2B3 SPG21 PICALM REV3L LCP1 PPP3CA SETD3 CD37 CD58 RHOB ZMIZ1 CCL22 AHNAK HNRNPA3 RNFT1 ZFAND5 THBS1 COTL1 PAPSS1 TM6SF1 ALOX5AP HTT ZNF706 CALM2 ATP6V0B CARD8 IFNGR1 DYM CST7 SLC3A2 FOS ATP6V0D1 TFEB GSAP PEA15 KIAA0232 TGIF1 VAMP4 TMEM230 NAB1 GALC ADAM10 RXRA PITPNA SEC63 CXCR4 ITGAE IFFO1 MAP3K4 PDE4A RNH1 VPS13D HERPUD1 CHP1 USP4 C5AR2 SH3BGRL3 EIF3L SLC38A2 FPR1 PTGS1 CALR HMGN2 POLR2L SERP1 PCMT1 RCBTB2 WDR26 PLCB2 KRT10 TPST2 GPATCH2L EMP1 ZCCHC14 BICD2 CPPED1 PYCARD	down	***
VERHAAK_GLIOBLASTOMA_MESENCHYMAL	0.0000000	0.0000003	0.7614608	-0.3794269	-2.048113	201	RAB11FIP1 SWAP70 LRRFIP1 THBD ENG C5AR1 NCF2 SLC11A1 TGFBR2 LILRB3 ARHGAP29 ANXA1 SH2B3 CLCF1 MAN2B1 ITGA5 IFI30 LCP1 LAIR1 GRN CASP5 MSR1 CYBRD1 CASP1 PLAUR DAB2 DRAM1 THBS1 PLBD1 LY96 TMBIM1 LAPTM5 RBMS1 PTPRC TLR4 DSE VAMP5 HEXB PROCR EMP3 LTBP2 HK3 CTSZ RAC2 PLK3 RHOG CSTA PTGER4 ACSL1 RRAS RBKS EHD2 ALDH3B1 DOK3 TEC LGALS3 PHF11 KYNU LTBP1 CLEC2B PLA2G15 CPQ TNFAIP8 MS4A4A SP100 SCPEP1 S100A4 ICAM3 SIGLEC9 CTSC THEMIS2 IQGAP1 CNN2 SERPINE1 LHFPL2 FHOD1 TGOLN2 BDKRB2 FPR3 FXYD5 MFSD1 MAN1A1 TES WWTR1 PDPN PIGP	down	***
HOXA9_DN.V1_UP	0.0000000	0.0000017	0.7337620	-0.3892703	-2.047474	164	SGK3 PECAM1 MNDA SNX10 PTPRE THBD FYN SAMHD1 ST3GAL6 ZCCHC2 NCF2 AGTPBP1 FUCA1 FRAT1 IFI30 PAQR3 ZFYVE16 TFEC FBXL5 BST1 KLF4 COQ10B UHRF1BP1L LY96 HPSE CLK4 FCER1G AKIRIN1 TDRD7 FRY PHTF2 SERPINB8 MAP4K4 TYROBP OSTM1 TMEM251 PTGER4 GLIPR1 GPR183 ENTPD4 TNFRSF10B FOS KIAA0232 CD86 GALC ATXN1 FCGRT TOB1 STX12 CRY1 ACYP2 GPR18 PLAA SESN1 SLC35D2 VASH1 IER5 MS4A4A IFFO1 SCPEP1 ICAM3 THEMIS2 LPAR6	down	***
MITSIADES_RESPONSE_TO_APLIDIN_UP	0.0000000	0.0000000	0.9653278	-0.3525314	-2.047405	383	KMO SC5D RAPGEF2 MIR22HG CLDND1 BDNF THAP9-AS1 BACH1 FOSL1 VAMP2 IDI1 NUDT9 OTUD4 FRAT1 TRIB1 CASP9 CCNL1 AVPI1 KIAA0355 HBEGF EIF1 ABCG1 KLF6 STOM RBM4 NFE2L2 NDEL1 CLK1 BTG3 MCL1 DIABLO RHOB MAP2K3 MTMR6 FOXO1 SRSF5 PIP5K1B KLF4 ID3 STK17B MAP1LC3B DENND3 PDE8A GMPR CCL3 RBMS1 PDE3B ID2 DUSP11 ARC PNRC1 CLK4 UBE2B DUSP1 ALOX5AP ELK3 BRF2 SH2D2A HES1 MAFF NRBF2 RABGGTB RSRC2 CDKN2AIP HGSNAT RPS6KA2 MOB4 MYLIP AREG RYBP CREM CTSS OASL NXF1 NECAP1 JAK1 PPP1R15A SKIL IFRD1 GLIPR1 ACKR3 STX5 MORC3 TSPYL1 RGS13 DENND4A SNRK SLC3A2 KLF2 FOSB DDX18 SPOP ADPRM BCAS2 PEA15 JMJD6 DUSP5 IRS2 C16orf72 HBP1 TERF2IP GABARAPL1 STX12 KANSL2 N4BP2L2 RGS2 SERINC3 MR1 DBNDD2 ATAD2B GTF2B JUND GEM ICAM1 LDLRAD4 INTS6 NEK1 CXCR4 SIK3 TOB2 ARIH1 OSER1 FNBP4 NFKBIA PDE4A NFU1 MTUS1 ABCA8 TNFSF9 P2RX1 ZNF165 SAMSN1 RORA THEMIS2 LDLR C2orf42 SFPQ FNBP1 ATP6V0A1 HERPUD1 PHYH CDC14A BHLHE41 DUSP6 AKTIP CENPC	down	***
BURTON_ADIPOGENESIS_PEAK_AT_2HR	0.0001639	0.0029057	0.5188481	-0.4985517	-2.047383	42	BTG2 NR4A1 FOXC2 RHOB MAP2K3 KLF4 ID3 THBS1 CXCL2 DUSP1 IL6 JUNB RHOJ PPP1R15A ACKR3 FOS FOSB RGS2 ETS2 CEBPD SERPINE1 NR4A2 ZFP36 DNAJB4 DNAJB1 PTGS2 TNFRSF1B TNFAIP6 DNAJB6	down	**
SLEBOS_HEAD_AND_NECK_CANCER_WITH_HPV_UP	0.0000244	0.0005896	0.5756103	0.5149436	2.046789	65	RIBC2 SPICE1 SLFN13 ABCA17P EIF2B5 TFDP2 MCM2 HAUS5 C5orf34 NR2C2AP TMEM41A HLTF KIF15 CENPW SDHAP1 LIG1 TOPBP1 ASS1 ACTL6A EHHADH RAD18 CDKN2C EZH2 CXCL17 POLR2H WDR53 GK5 CDC7 CENPK MEI1 MCM6 RAP2B NEFH YBX2 CELSR3 NUP210 RNF32 C9orf40 CRYGS ALG6 FAM111B	up	***
REACTOME_FOXO_MEDIATED_TRANSCRIPTION	0.0000300	0.0007055	0.5756103	-0.4756119	-2.046318	54	ATXN3 CAT CAV1 CITED2 NR3C1 TXNIP PLXNA4 AKT3 TXN FOXO1 KLF4 CDKN1A PINK1 BTG1 YWHAZ FOXO3 NFYC SOD2 KAT2B SMAD2 RBL2 CREBBP SIN3A SMAD4 CDKN1B YWHAB EP300 SIRT1 NFYB	down	***
MODULE_44	0.0000000	0.0000000	0.8390889	-0.3680735	-2.044584	266	TNR SLPI ACP5 CD52 PECAM1 FABP4 CLEC3B LPXN CYP4B1 LIPA ENG CD44 CAV1 FXYD2 MAL FUCA1 CD22 EPB41L3 TGFBR2 RFTN1 HSPG2 CD8A APOD ASAH1 RNASE1 LCP1 LAIR1 GRN SRGN TCAP APOC1 CD37 KRT4 PTPN12 EVI2B CFD STAT5A SCP2 BIRC2 GPA33 CPVL DAB2 CLDN5 GMPR LAPTM5 PTPRC SELL PNRC1 IGFBP2 M6PR CD53 PER1 ALOX5AP N4BP2L1 IL7R HLA-DQA1 CRIM1 ARHGDIB EMP3 CD8B FAM107A METAP1 SLCO2B1 AQP3 CD48 RAB31 ETS1 RAC2 RHOG IFNGR1 JAK1 PIK3R1 IRF8 GMFG RASSF2 CELF2 CD34	down	***
GO_CONDENSED_NUCLEAR_CHROMOSOME_CENTROMERIC_REGION	0.0000630	0.0013132	0.5384341	0.6829063	2.043991	21	BUB1B CCNB1 NDC80 PLK1 NUF2 AURKB CENPA BUB1 AURKA REC8 CENPO	up	**
GO_CHROMOSOMAL_REGION	0.0000000	0.0000000	0.8634154	0.4300730	2.043147	278	PKHD1 HELLS HJURP CHEK2 BUB1B NUP107 NEK2 CCNB1 CENPF THOC3 NDC80 PIF1 TTK NABP2 PLK1 NUF2 CDCA8 AURKB CENPA MCM4 MCM2 ORC1 DYNC1I1 MIS18A NCAPD2 ZWINT CDT1 DCTN2 SPDL1 STAG3 BOD1 TP53BP1 KNTC1 BUB1 CENPL AURKA CBX3 REC8 ATR TPR KIF2C MCM7 MAD1L1 CENPW CDCA5 PRKDC MCM3 CHEK1 MAD2L1 CENPO XRCC1 SPC24 DSCC1 BLM PML PARP1 INCENP KNSTRN TERC CBX5 CDK1 CENPH BIRC5 NCAPG DNA2 FEN1 EZH2 SPAG5 TRAPPC12 MTBP CBX1 RECQL4 CENPP TEP1 RANGAP1 DNMT1 TELO2 DCLRE1C KIF22 HIRA RAD51D CENPQ ESCO2 LRWD1 POLD1 NUP85 SLX4 RAD50 CENPK CENPV CKAP5 CENPM RPA1 MCM6 DNMT3A THOC5 WRNIP1 DYNC1LI2 CENPT MCM5	up	***
GO_ENDOTHELIAL_CELL_MIGRATION	0.0000000	0.0000015	0.7337620	-0.3841501	-2.043130	184	ANGPT4 ACVRL1 SASH1 HMOX1 SOX18 TEK PECAM1 PPARG ADTRP GATA2 EMP2 BMPER CDH13 BMPR2 TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 PTPRM ADAM17 CLEC14A HSPB1 FOXP1 GATA3 NR4A1 RGCC NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 TNFSF12 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NUS1 ANXA3 SRF PRCP	down	***
LIM_MAMMARY_STEM_CELL_DN	0.0000000	0.0000000	0.9436322	0.4209268	2.042952	370	RHPN2 LTF ALDH3B2 PPM1H CEACAM1 PRLR BIK PPP1R1B BDH1 GABRP NGEF TFAP2A DNAJC12 FRK WFDC2 RAB3IP SPDEF CREB3L4 SLC5A1 ILDR1 BAIAP2L1 ACOT8 SFXN1 LSR GRB7 ACY1 CIB1 TDRKH MARVELD3 VILL AP1G2 GOLPH3L TJP3 MANSC1 CLDN1 TMEM41A NUDT1 ANO9 FOXA1 STAP2 CBLC PAFAH1B3 IDO1 IFT43 ICA1 COASY TPCN1 TOM1L1 MCCC2 AP1M2 CD24 SIDT1 SLC9A3R1 PDZK1IP1 SPINT1 EHHADH TBC1D8 TST GLE1 MBOAT1 PIGO TMED3 CMAS MB PAK1 KRT18 SLC39A11 FAM221A ARPC1A ABHD17C NUDT2 REEP6 WDR31 SDCBP2 FADD RAB11FIP4 RALGPS1 MYO5B CXCL17 SUSD4 RNASEH2A PYROXD2 MPI GIPC1 TSPAN17 ST14 DCLRE1C ARHGEF16 ATP6V0E2 ADAT1 UROS HDHD3 PLEKHG3 MAPK13 RAD51D MTA3 OS9 HID1 ACAD10 GSTK1 KRT19 SGSM3 ELMO3 SIL1 ESR1 POLB GOLM1 ERBB3 TFCP2L1 KRT8 MYO5C SSH3 ANKRA2 SIRT5 C1orf56 C5orf22 SLC35A3 ADD3 SCYL3 CCNG1 CORO2A MVP ALG8 EPCAM RER1 CDH1 DTX3L GRHL1 PCBD2 STAT6 OSBPL10 ARRDC1 HLCS MRPL9 SNX8 PTPRF ERBB2 ATG2A ALKBH6 CAMSAP3 CGN RAB25 KIAA1522 TLR5 RORC NUP210 ZSCAN20 MUC1 TK2	up	***
GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_MIGRATION	0.0000440	0.0009729	0.5573322	-0.4754947	-2.041461	55	ANGPT4 HMOX1 GATA2 MIR27B ANXA1 MIR146A ADAM17 HSPB1 NFE2L2 AKT3 FOXC2 MAP2K3 STAT5A AMOTL1 THBS1 PIK3C2A NUS1 ETS1 RHOJ TGFB1 MIR23A	down	***
GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN	0.0000001	0.0000034	0.7049757	-0.3845734	-2.041251	180	SASH1 INSIG1 ENG COQ2 LPL CD44 AQP9 SLC39A8 NR3C1 BCL2A1 OTUD4 FAM49A IGSF6 PFDN1 RFTN1 ADA SLC7A7 PTX3 SERPINB9 LAIR1 TFEC EPM2AIP1 BTG3 TFRC ATP6V1H STAT5A TBC1D9 CASP1 PTAFR NFKB1 KCNMB1 CCL4 M6PR N4BP1 CRIM1 RABGGTB HCK ZNF330 KANK1 HCAR3 CD80 PDHX FLT1 SOCS3 NECAP1 CD48 STAT4 RAC2 IFNGR1 GRB2 ZBTB24 DENND4A NDUFV2 CDK14 RHOQ RIN2 ZNF175 DDX18 EHD1 SERPINB1 NAB1 UTP3 KYNU PDE4B IL18 TNFAIP8 NBN RIPK2 UBE2D1 MAP3K4 NFKBIA ADORA2A PTEN DMXL2 FNBP1 ZFYVE26	down	***
CHASSOT_SKIN_WOUND	0.0010130	0.0128438	0.4550599	-0.7789819	-2.040949	9	EGR2 JUN JUNB REL FOS KLF2 FOSB EGR1	down	*
GSE3982_DC_VS_BCELL_UP	0.0000000	0.0000007	0.7477397	-0.3835778	-2.039678	176	GPD1 SLC31A2 TAL1 FBP1 LRRFIP1 CCRL2 SAMHD1 FOSL1 CLEC10A ALAS1 TGFBR3 CD1C FUCA1 LAMP1 PILRA CD36 ANXA1 ARHGAP10 ARSB ABHD6 RGCC TNS1 SPRY2 SLC19A1 CRTAM ATP6V1H SETD3 PDGFA TUBB6 ARRB1 BST1 STX3 SOCS2 TPP1 CDKN1A ATF3 CDS2 PAPSS1 ZBTB43 TM6SF1 MMP19 CLN8 SCEL PHACTR2 RAB8B MITF RAB31 HK3 TYROBP RCAN1 PODXL CD83 LSM1 AGPS SORT1 PEA15 CTNNAL1 MCUR1 CD86 RXRA SLC31A1 MS4A4A NLRP3 ALDH2 SLC2A9 ULK2 DAPK1 CD1E PDE4A	down	***
THUM_SYSTOLIC_HEART_FAILURE_UP	0.0000000	0.0000000	0.9101197	-0.3532102	-2.039381	367	SC5D CD52 SFRP4 MNDA CAT RDX ENG HSD17B11 PLEKHF2 ST3GAL6 CALCRL CYB5R3 INPP5A SFR1 ARL8B P2RY13 LAMP1 SLC11A1 TGFBR2 SCARA3 RHOA ADAM17 ENTPD1 EIF1 PICALM RNF125 SPIRE1 RNASE1 LCP1 LAIR1 JAM3 ZEB1 SRGN FLI1 EVI2B MSR1 AGO4 MPEG1 CASP1 TSPAN12 ZFAND5 THBS1 ARNTL SOCS2 TPP1 CLIC4 LY96 LAPTM5 PTPRC CXCL2 SELP CCL4 TLR4 M6PR CD53 FCER1G ALOX5AP UTP23 RBMS3-AS3 BCLAF1 ARHGDIB ACTR2 CLIC5 TSPAN18 CREBRF SLC8A1 VAMP3 ID4 CTSS LINC00339 IL2RB SNAP23 OASL UTRN C1QA HPGDS GIMAP2 LTBP2 HRH1 RAC2 TYROBP APBB2 IRF8 MBNL2 MFAP4 GTDC1 YWHAZ RALB ZBED5 APOL4 MORF4L1 NECAB1 YTHDF3 CD74 GIMAP1 EPHA3 TMEM230 NAB1 PDCD1 PLSCR4 ANKRD12 CLEC2B MR1 TRAC WDR1 ZNF438 RAB5A CDC42EP3 MS4A4A CXCR4 EPHA4 ACTB KPNA4 RBMS3 RBM48 BCAT1 CTSC EDN1 B3GNT2 DAZAP2 LPAR6 CNOT8 MIER3 LYZ C1QB CRTAP TMEM43 DKK3 CX3CR1 FUS GAS5 ITGB1 HP1BP3 PLXDC2 PIK3CG DNAJB4 XPO7 FPR3 BSG C6orf62 HLA-DRB1 ANGPT2 MATR3 MAN1A1 FCGR3A PAXBP1 SKAP2	down	***
GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP	0.0000000	0.0000017	0.7337620	-0.3853242	-2.039258	172	GPR65 ARRDC4 EGR2 FGF10 GIMAP6 TRIB1 IER2 CD5 SBDS TM2D3 PPP1R15B MAP3K8 ADIPOR1 NR4A1 ADRB2 TMEM41B CLK1 SRGN TFRC FBXO8 ITPRIP ADO AOC3 COQ10B UBTD1 STK17B ADAMTS9 CCL4 CD302 PNRC1 PER1 DUSP1 ELMSAN1 MAFF SRF ETF1 VAMP3 LRRTM2 KIF13A PHACTR2 ETV3 ARL5B PLK3 JUNB DNAJA1 PPP1R15A PTGER4 GPR183 PTGER2 GRASP PREX2 FOS FOSB TGIF1 TSC22D1 DUSP5 KYNU ADAMTS15 EMC4 GEM MGAT2 SEC63 TOB2 RBM18 TTC19 GTPBP8 GPR171 NABP1 MS4A2 PIM3 EGR1 FKBP1B PNLDC1 ZFP36 CD69 DNAJB1	down	***
GO_SEQUESTERING_OF_TRIGLYCERIDE	0.0010628	0.0133296	0.4550599	-0.7391838	-2.039060	11	ABHD5 OSBPL11 PPARG IL1B LPL	down	*
REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS	0.0008002	0.0107062	0.4772708	-0.6589052	-2.038577	16	LIMS2 LIMS1 PARVB VASP FERMT2 FLNC ACTB PARVA RSU1 ITGB1	down	*
DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP	0.0000000	0.0000002	0.7749390	0.4395224	2.037779	205	PTGES HELLS RUVBL1 KCNK5 CDC45 TICRR MCM10 PAX9 C1QTNF6 DEPTOR DNAJC12 FRK PLEKHH1 BRCA1 CDCA7 SDK2 ECE2 SLC27A2 CDC6 STC2 RBBP8 UHRF1 MCM4 MCM2 CA12 XRCC2 DTL MCM8 MOCOS NR2C2AP NOS1AP EXO1 CHAF1A TPBG WDR3 POLA2 MCM7 MMS22L WDHD1 AKAP1 MCM3 BRI3BP SLC9A3R1 CHEK1 DSCC1 BRIP1 FLNB MBOAT1 PLOD2 POLE2 RAPGEFL1 NAV2 E2F1 UNG FEN1 TMEM120B NOP2 FAM102A PDCD11 SLC26A2 MYBBP1A KIF21A SLC22A5 GINS2 IFNAR2 SEC14L2 OLFML3 MRPS23 NOL6 MCM6 MCM5 ANXA9 TFAP4 GINS3 LRIG1 EXOSC5 SLC1A5 CHRNA5 PRIM1 BLVRB SYBU WDR4 WDR76 CELSR2 POLR1B PAICS RRS1 ZNF367 KCNK6 TPM1 ATP6V1C2 LONRF2 SFXN2 PEX11A HR RBL1 ABHD2	up	***
REACTOME_DNA_REPLICATION_PRE_INITIATION	0.0000166	0.0004304	0.5756103	0.4993123	2.037564	77	CDC45 MCM10 PRIM2 POLE CDC6 E2F3 MCM4 MCM2 ORC1 MCM8 CDT1 POLA2 MCM7 E2F2 MCM3 ORC6 PSMD4 POLE2 GMNN E2F1 PSMB5 PSMC4 PSMA5 PSME2 PSMD2 CDC7 PSMB3 RPA1 MCM6 MCM5 PSMB4 PRIM1	up	***
MIR2861	0.0000159	0.0004142	0.5756103	0.5004556	2.037075	76	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA7 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 SYT12 PCDHGA12 PCDHGC5 PCDHGC4 YKT6 E2F2 HOXC6 PCDHGA4 PCDHGB7 PCDHGA3 MGLL TMEM120B PCDHGA2 STOML1 SEMA4G CHD5 PCDHGB1 FIBCD1 CHTF8 KIF21B POLR2J3	up	***
SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP	0.0000002	0.0000088	0.6901325	-0.4037934	-2.036496	137	EPAS1 SC5D HMOX1 FBP1 CYP27A1 TIE1 THBD INSIG1 ENG AQP9 C5AR1 MARCO NCF2 CD9 ABCB1 HBEGF GM2A ABCG1 ANPEP TNS1 CD93 CD58 BST1 THBS1 MAFG TMBIM1 CDKN1A P2RY2 HPSE SMAD7 DSE MAFF HCK CLN8 CREM IFNGR1 DAPK2 MCAM ACSL1 TIMP2 TGFB1 CD1D CCR1 CCL20 EPHA4 GLUL BCAT1 KIT P2RX1 NRG1 SPHK1 EGR1 DKK3 FPR1 QSOX1 WNT5A	down	***
chr4q24	0.0004302	0.0065071	0.4984931	-0.5494883	-2.035955	29	EMCN SLC39A8 MANBA TET2 TET2-AS1 PPP3CA UBE2D3 NPNT NFKB1 CXXC4 SLC9B1 PPA2 LRRC37A15P	down	**
GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT	0.0000039	0.0001254	0.6105269	0.4812235	2.034082	96	HMGA2 TICRR CHEK2 CCNB1 BRSK1 E2F8 GTSE1 CDC6 TFDP2 ORC1 CDK5RAP3 CASP2 TOP2A AURKA EME1 CLSPN PRKDC CDC25C SOX4 EME2 TOPBP1 NEK11 MDM2 BLM PML CNOT3 CDK1 RFWD3 E2F1 CNOT11 CNOT2 RAD9A	up	***
MODULE_342	0.0000001	0.0000031	0.7195128	0.4473890	2.033409	178	LTF TSPAN8 MUC13 FOXA3 EGLN3 CDH17 KRT5 LAD1 PRSS2 WFDC2 GINS1 PRR15L E2F8 DNMT3B LAMP5 AKR1C1 H19 C4orf19 AGR2 SPINT2 GRB7 XDH LILRB4 DZANK1 CYP3A5 GPX2 MAP7 LAMC2 FOXA1 F2RL1 MYO10 FGG CDCA5 RNF43 HOOK1 CD24 SLC9A3R1 B3GNT3 LRRC37A4P MST1R PRMT6 BACE2 LRRC61 PTGFRN WWC1 MIPOL1 CXCL14 KRT18 FAT1 PLA2G2A REEP6 LRRC4 CDH3 SLC25A18 NGFR MMP7 GALNT3 KRT19 FXYD3 CA11 LIPG UBXN6 KRT8 ANXA9 SSH3 RTKN RHOBTB1 ANK3 EPCAM PRSS8 CDH1 FMOD AIFM2 WLS PTPRF VWA1 FBLIM1 FZD3 RAB25 TMEM98 NUP210 KRT17 MUC1 AZGP1	up	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP	0.0000001	0.0000034	0.7049757	-0.3863375	-2.032826	168	RAPGEF2 MIR22HG SAMHD1 BMPR2 PLEKHA1 TRIB1 HEG1 TOE1 ANXA1 DPEP2 CNST ASAH1 NAAA CLEC7A TRAF6 TCF7L2 ITPRIP AHNAK PSTK CASP1 KLF4 COQ10B NR1D2 SNORA28 DUSP1 RNF139 PLEK IL7R UBASH3B PIK3R5 MAFF NCOA1 SNN SLC25A33 TMEM9B SGK1 SOCS3 JUN MAP4K4 TYROBP JUNB RAPGEF1 FYTTD1 SKIL CD83 KLF2 PTP4A1 TRAPPC10 NAP1L5 VAV3 GSAP CHRAC1 ABHD13 TSC22D1 IRS2 PIM1 TOB1 RGS2 KTI12 INO80 USPL1 EPHA4 POLR2M SOAT1 EPB41L4A MTUS1 ZFAND2A SETX EXOG CDC14A TNFSF8 NR4A2 S100A8 SLC26A11 YRDC CD69 MFSD1	down	***
GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN	0.0000001	0.0000042	0.7049757	-0.3829525	-2.032648	180	CXCL3 MS4A7 KLF13 ZC3H12C FABP4 GREM2 CITED2 SLC15A3 IL1RN CBL CD22 FAM49A PLA2G7 NFIX ADAM17 PLXNA2 ANXA5 KLF6 TFRC CWC22 FABP5 CASP1 ITM2B AIRN ZFAND5 DRAM1 KLF7 ATF3 HPSE PLEK N4BP1 RUFY3 HGSNAT LACC1 NINJ1 RBPJ FMNL2 DDHD1 CYB5R1 SERPINB8 SNX29 USO1 CTSZ PTGER4 SNX2 PSTPIP2 HNRNPD AZIN1 SAV1 EHD1 ITGA9 FPR2 MCUR1 NAB1 IFNAR1 C16orf72 GPR84 SOD2 BRI3 STK40 ETS2 RNF2 ICAM1 NLRP3 TRAF1 PLGRKT NFKBIA MCOLN2	down	***
GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP	0.0000001	0.0000034	0.7049757	0.4468646	2.031026	178	KLC3 CDC45 TICRR BUB1B NEK2 MND1 NDC80 PIF1 DEPDC1B ANLN STIL MSTO1 PLK1 CDC6 TPX2 RBBP8 SPATS2 RAD54B PRC1 DTL NCAPD2 DCTN2 TNC MELK EXO1 AURKA REC8 RAB19 POC1A RAD54L ANKRD13B KIF11 FANCD2 CHAF1B BRI3BP CHEK1 MAD2L1 AHCY RAD51AP1 SPC24 PERP BRIP1 PML RNF216 NCAPG2 C12orf75 ASF1B CDK1 STON2 CENPH ARPC1A DNA2 SAPCD2 UQCC2 DIAPH3 FGFR1OP TACC3 TK1 ADAR ANP32E LIN37 FHL2 NFE2 RNASET2 SUOX MARCKS ALMS1 CCNA2 SHCBP1 HK2 FARSB PFKM ARHGAP11A MXD3 DTNBP1 PAICS NDUFB7 COX6B1 C4orf46 CYP11A1	up	***
PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	0.0001832	0.0031854	0.5188481	-0.4870573	-2.030494	44	ANGPT4 TEK FYN ELF2 ITGA5 CRK STAT5A FOXO1 NFKB1 CDKN1A ELF1 ETS1 PIK3R1 GRB2 MAPK8 DOK2 FGF2	down	**
GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_UP	0.0000000	0.0000023	0.7195128	-0.3900225	-2.029545	159	USP12 CD55 CPEB2 TTC7B RUNDC3B OTUD1 CD44 PDE1B NEDD4L TBXA2R S1PR1 CD9 ZBTB2 FAM49A PDE2A ATP2B1 CYP17A1 RAPGEF4 LATS2 C1orf21 ACOT2 FOXP1 NR4A1 SGTB ZSWIM6 KLF4 PDE8A SELL SMAD7 PIK3R5 CRIM1 S1PR4 DNAJC27 SOCS3 SH3BP5 ETS1 MAP4K4 JAK1 CCR7 PIK3R1 FRYL GPR183 COBLL1 CD7 KLF2 MBP BIN2 C19orf38 SMPDL3B VAV3 PDLIM1 GNA13 RXRA AMD1 RNF138 IQSEC1 CXCR4 MEX3C GPD1L SSH2 KIF1B CCND3 ZBTB40 ARHGEF18 TNFSF8 CNR2 ATP11B CX3CR1	down	***
GO_CONDENSED_NUCLEAR_CHROMOSOME_KINETOCHORE	0.0001328	0.0024444	0.5188481	0.7410734	2.029453	15	BUB1B CCNB1 NDC80 PLK1 NUF2 CENPA BUB1 REC8 CENPO	up	**
GO_NEGATIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT	0.0000086	0.0002472	0.5933255	-0.4094422	-2.029198	102	ANGPT4 SEMA6A TEK PPARG HHEX TIE1 WNT4 ECSCR GTF2I TBXA2R NFATC3 HSPG2 RHOA MIR146A MMRN2 PTPRM RGCC SPRY2 GPR4 ROCK2 KLF4 ROCK1 THBS1 ADAMTS9 CLDN5 PDE3B MIR24-2 TGFB2 CD160 NOTCH1 NPR1 KLF2 ISM1 VASH1 EPN2 SEMA4A EPHA2 FOXJ2 STARD13 SERPINE1 ATF2 CX3CR1 MIR640 MIR2355	down	***
GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN	0.0000001	0.0000037	0.7049757	-0.3856382	-2.029146	168	DENND5A PECAM1 SECISBP2L RAPGEF2 PTPRE ENG MMRN1 LMO2 ST3GAL6 NR3C1 CD9 SCARF1 ERG EDEM1 UBL3 ADA EIF1 ITGA5 KLF10 GLS HLX FOXJ3 AKT3 ZFYVE16 PPP3CC ZMIZ1 PTPN12 STAT5A SRSF5 YBX3 ROCK1 SOCS2 KLF7 NPAS3 CDS2 CTBS RECK CCND2 WFS1 GNAQ AFF1 CRIM1 S1PR4 RYBP AK1 SERPINB6 CD34 ACSL1 FOXO3 TTBK2 MME BAZ2B N4BP2L2 PDE4B SEC63 CALCOCO2 BRWD1 TMEM87A THEMIS2 WDFY3 BMI1 DMXL2	down	***
GSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP	0.0000001	0.0000047	0.7049757	-0.3864190	-2.028098	165	CXCL3 DENND5A CCM2L IL1B INSIG1 AQP9 ZCCHC2 SLC39A8 CD22 TNFRSF8 ATP2B1 SLC7A7 TNIP3 MAP3K8 RNF144B PTX3 LCP1 ARHGEF2 TCF7L2 CASP5 ZMIZ1 STAT5A SGTB LIMS1 ST3GAL2 THBS1 FMNL3 CXCL2 PNRC1 DSE SLC6A6 PIAS1 BTG1 IL6 NSMAF SOCS3 MAML2 OASL ZNF835 CD48 CELF1 MAP4K4 RCAN1 PTGER4 SKIL HSPA13 OSM ATP13A3 RASSF2 FPR2 IRS2 SOD2 RGS2 CCL20 CEBPD TAB2 TMEM184B PCBP1-AS1 HNRNPC TNFSF9 SAMSN1 CNN2 LINC00884 AFTPH VPS13D ADAM33 PRKCH S100A8 FPR1 MSANTD3 EBF1	down	***
SMID_BREAST_CANCER_RELAPSE_IN_BONE_UP	0.0000206	0.0005155	0.5756103	0.4992277	2.027957	73	CCNO TFPI2 PTPRT HBA1 GALNT6 TOX3 CLGN SPDEF TFF3 BCAS1 AGR2 CA12 PAH SLC4A8 KAZALD1 C9orf116 CHAD TOM1L1 INPP4B DCLK1 MB TSPAN1 SYT1 SIL1 ESR1 GALNT7 ANXA9 CEACAM5 TTC12 TMEM101 CAPN9 MUC1 NELL2 NAT1 GSTT2 PGAP3	up	***
NIKOLSKY_BREAST_CANCER_7Q21_Q22_AMPLICON	0.0000289	0.0006815	0.5756103	0.5271404	2.027130	57	TFPI2 ASB4 BET1 BAIAP2L1 DYNC1I1 CYP3A5 PPP1R9A PON3 TRRAP ZKSCAN1 PON1 PON2 ARPC1A ZSCAN25 SLC25A13 PEG10 ZNF789 ZKSCAN5 COL1A2 LMTK2 ASNS FAM200A CLDN12 CPSF4 ANKIB1 GTPBP10 PDAP1	up	***
REACTOME_CELL_CYCLE_CHECKPOINTS	0.0000000	0.0000001	0.8012156	0.4318418	2.025685	232	CDC45 MCM10 CHEK2 BUB1B NUP107 CCNB1 CENPF NDC80 BRCA1 GTSE1 PLK1 NUF2 CDCA8 AURKB CENPA CDC6 CCNB2 RBBP8 MCM4 MCM2 CDC25A ORC1 DYNC1I1 MCM8 ZWINT SPDL1 EXO1 TP53BP1 KNTC1 RHNO1 BUB1 CENPL ATR KIF2C MCM7 MAD1L1 CLSPN MCM3 CDC25C TOPBP1 CHEK1 ORC6 MAD2L1 PSMD4 CENPO MDM2 SPC24 PKMYT1 BRIP1 BLM INCENP ANAPC5 CDK1 CENPH BIRC5 PSMB5 DNA2 KIF2A ANAPC7 DYNLL2 PSMC4 CENPP RANGAP1 CCNE1 CDC23 PSMA5 RAD9A PSME2 CENPQ ANAPC1 PSMD2 NUP85 CDC7 RAD50 CENPK CKAP5 PSMB3 CDC20 CENPM RPA1 UBE2V2 MCM6 DYNC1LI2 CENPT MCM5 UIMC1	up	***
BONOME_OVARIAN_CANCER_POOR_SURVIVAL_UP	0.0004573	0.0068475	0.4984931	-0.5465334	-2.025006	29	KL KCNAB1 UBL3 REV3L ITM2B RUNX1T1 PDE8A RECK HERC1 SEC63 LIMCH1 EID1 RAB2A ZBTB16 RB1CC1 SRSF11 CCPG1 SIRT1 EFEMP1 FAT4	down	**
GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_5_PHOSPHATASE_ACTIVITY	0.0012124	0.0147580	0.4550599	-0.7339841	-2.024717	11	FIG4 INPP5K PTPMT1 INPP5B PIKFYVE	down	*
GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_UP	0.0000000	0.0000019	0.7195128	0.4486175	2.024715	166	FOXM1 HJURP CEP89 NEK2 CENPF PRIM2 BRCA1 RACGAP1 IQGAP3 E2F8 TRAIP POLE ASPM STIL IFT27 CDCA8 PTTG1 ESPL1 CCNB2 RBBP8 NCAPD2 TAMM41 WDR62 KIF23 MKI67 CENPL HHAT SNCG MCM7 E2F2 POC1A KCNV2 CHAF1B TOPBP1 MAD2L1 CKAP2L PIH1D1 MRPS11 PKMYT1 GLE1 PSRC1 CKS1B NCAPG2 NUSAP1 CDK1 KCNE3 CENPH BIRC5 E2F1 SPAG5 CENPP CAPS2 TACC3 KIF22 TUBA8 CHTF18 CENPQ GINS2 CEP128 CENPV CENPM ABCA7 MCM5 HEATR1 HAUS6 HAUS4 TC2N PRR11 RTEL1 RFC5 ARHGAP11A NDUFS8 CDC25B UBE2C GPN1 NUP210 DDB2 KIF24 PTPN13 TEX9	up	***
AMIT_EGF_RESPONSE_60_HELA	0.0002465	0.0041020	0.4984931	-0.4929519	-2.024386	42	CITED2 KLF10 KLF6 TIPARP RHOB MOAP1 PER1 HES1 MBNL2 GPRC5A RUNX3 FOSB SOD2 LDLR NAA15 PMAIP1 SERPINE1 NR4A2 NKTR NR4A3	down	**
GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_DN	0.0000000	0.0000016	0.7337620	-0.3812990	-2.024058	178	SMAD6 CXCL3 IL1A HMOX1 CPEB2 IL1B F2RL3 EGR2 GTF2E2 GPCPD1 IL1RN MOB1B IER2 SPG21 TRA2B SLC25A17 BTG2 MAP3K8 NR4A1 NDEL1 TMEM41B SRGN SOX7 BTG3 ATP6V1H PDGFA IL10 RAB12 LIN7C PLAUR SOCS2 FAM49B CDKN1A CXCL2 SELP CCND2 DUSP1 DSTN PLAC9 COPS4 PROCR ETF1 SGK1 SOCS3 KCTD12 JUNB DNAJA1 RCAN1 PPP1R15A IFRD1 EEA1 CD83 DDX5 FOS PELI1 EHD1 CD86 PIM1 TMEM70 STK40 ETS2 IST1 ICAM1 HSP90AA1 RBM18 NFKBIA TIMP3 MCOLN2 TNFSF9 MT2A YTHDC1 EGR1 SERPINE1	down	***
GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP	0.0000000	0.0000024	0.7195128	-0.3823209	-2.023364	172	ARHGAP31 GAPT ENG PLEKHF2 QKI MYD88 CDC42EP2 STX11 EPB41L3 TGFBR2 FAM49A IL23A ADA MTF1 TNIP3 MAP3K8 RNF144B LAIR1 SIRPA TMEM123 NFE2L2 EPM2AIP1 STAT5A ARRB1 PTAFR VASP STK17B THBS1 KLF7 CLIC4 TLR4 PNRC1 CCSER2 N4BP1 PIK3R5 CMTM6 LACC1 HCAR3 SYNPO2 PSEN1 OASL DNAJA1 RHOG ACKR3 PSTPIP2 GRB2 RBM22 TNFRSF9 TNFRSF10B ACSL1 RIN2 PIK3AP1 EHD1 SERPINB1 FPR2 KCNA3 PDE4B IER5 TAB2 NLRP3 RND1 MCOLN2 SAMSN1 CNN2 FNBP1 FJX1 CLEC4E DCUN1D3 EYA3 SRSF11 FPR3 UBE2W SERP1 IRF1 ADH1B CSF3 FAM89B NFKBIZ EBI3 RNF19B	down	***
GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN	0.0000000	0.0000022	0.7195128	-0.3875727	-2.023191	158	CLEC1B IL17RB USP12 KLF13 DYRK1A TGFBR3 SYS1 IGSF6 TMX4 TXNIP LATS2 ENTPD1 RNF125 GATA3 PPP3CA TMEM123 TRAF6 PPP1R13B SRGN SPI1 ZYG11B AHNAK ZSWIM6 COQ10B KLF7 PLBD1 ID2 ARHGAP9 RNF139 CLEC9A PIK3R5 TANC1 GABARAPL2 DCTN6 TYROBP CCR7 PNPLA8 RC3H1 LPCAT2 ZNRF3 WDR7 WDFY4 CELF2 XYLT1 ZFAND6 DCAF5 DUSP5 MIA3 C16orf72 TOB1 TSPO RNF138 IER5 MAFK RORA THEMIS2 IQGAP1 RNF13 FEZ2 FNBP1	down	***
RUTELLA_RESPONSE_TO_HGF_DN	0.0000000	0.0000005	0.7614608	-0.3696859	-2.022853	209	RAB11FIP1 EREG CD52 FCN1 PHACTR1 PECAM1 CD55 LTA4H DPYSL2 PID1 FYN LY86 LMO2 FCER1A MYD88 C5AR1 NEDD9 GAS6 TMX4 CCNL1 DPEP2 HBEGF SLC7A7 KLF10 RGCC TCF7L2 MCL1 CCNI FBXL5 CFD TLE4 CASP1 ZFAND5 STK17B DENND3 MYO15B ITPK1 CDKN1A SELL DNTTIP2 HLA-DQA1 MAPRE2 NCOA1 BTG1 CD48 SH3BP5 MAP4K4 TREM1 RABGAP1 CD83 PTGER2 PPM1F CELF2 PELI1 RUNX3 ICAM2 CHPT1 CD86 GALC APLP2 DECR1 RGS2 ETS2 RNF138 CCDC69 IER5 MS4A4A CXCR4 CDKN1C SIK3 NLRP3 ICAM3 NEK3 CYTH1 NRG1 SFPQ MIS18BP1 GRPEL1 CACNA2D3 FNBP1 HERPUD1 EGR1 DUSP6 FKBP1B NR4A2 CX3CR1 AOAH ITGAL FPR1 ZFP36	down	***
GO_RECOMBINATIONAL_REPAIR	0.0000007	0.0000270	0.6594444	0.4721178	2.022694	113	CDC45 PARPBP TIMELESS POLQ BRCA1 NABP2 FIGNL1 RBBP8 MCM4 MCM2 RAD54B XRCC2 MCM8 LIG3 GINS4 MAGEF1 TP53BP1 RHNO1 AUNIP REC8 MCM7 MMS22L HELB RAD54L MCM3 CHEK1 RAD51AP1 XRCC1 BLM RECQL5 PARP1 POLN RFWD3 AP5Z1 FEN1 MAD2L2 RECQL4 POLL RAD51D GINS2 SLX4 CDC7 RAD50 UBQLN4 PALB2 RPA1 MCM6 MCM5	up	***
GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY	0.0004302	0.0065071	0.4984931	-0.5415857	-2.022613	30	ACVRL1 CITED2 BMPR2 FGF10 TGFBR2 NODAL SMAD7 INHBA MAGI2 FSTL3 SMAD2 FKBP1A DACT2 SKI ACVR1C	down	**
GO_REPLICATION_FORK	0.0000272	0.0006462	0.5756103	0.5126934	2.022291	62	CDC45 MCM10 TIMELESS PRIM2 PIF1 UHRF1 XRCC2 GINS4 TP53BP1 POLA2 POLD2 SMARCAL1 MMS22L WDHD1 HELB MCM3 RAD18 BLM ZMIZ2 DNMT1 RAD51D GINS2 POLD1 RPA1 ZRANB3 HMCES PRIM1 RFC5 TONSL BCL6 TP53	up	***
PID_EPO_PATHWAY	0.0004573	0.0068475	0.4984931	-0.5406988	-2.019301	30	CBL SH2B3 RAP1A STAT5A EPOR NFKB1 SOCS3 RAPGEF1 PIK3R1 GRB2 PLCG2 MAPK8 TEC IRS2	down	**
GO_INTERLEUKIN_6_MEDIATED_SIGNALING_PATHWAY	0.0013765	0.0162382	0.4550599	-0.6068315	-2.018411	19	CBL SPI1 CEBPA IL6 SOCS3 JAK1 SMAD4 CTR9 C1QTNF4 FER JAK2 IL6ST STAT3 IL6R PTPN11 STAT1	down	*
MARKEY_RB1_ACUTE_LOF_UP	0.0000000	0.0000012	0.7337620	0.4354766	2.018177	206	HMGA2 TRIP13 KIF20A HJURP CDC45 NEK2 CCNB1 UBE2T BRCA1 RACGAP1 IQGAP3 E2F8 ANLN PLK1 CENPA ECT2 CDC6 CCNB2 FIGNL1 MCM4 TYMS PRC1 CCNF DTL COX6B2 CDT1 SPDL1 RANBP1 DNPH1 KIF23 MKI67 BUB1 AURKA SAE1 KIF2C MCM7 RRM2 HELB KIF11 MCM3 CHAF1B CDC25C TOPBP1 DNAJC9 ORC6 MAD2L1 AHCY RAD51AP1 DCTPP1 MDM2 PERP PPP5C IDH2 PARP1 CKS1B NUSAP1 TMEM106C CBX5 ASF1B ANAPC5 CDK1 BIRC5 GMNN NAV2 E2F1 PRRX2 KIF2A ETFB DLGAP5 KIF22 TRIM37 TK1 DTYMK HIP1R CENPK SASS6 YLPM1 CKAP2 MCM5 LSM4 CCNA2 PRIM1 BANF1 PTPRVP RFC5 DOHH HAS1 RAD51 TPGS2 SCOC	up	***
GO_REGULATION_OF_CHROMOSOME_SEGREGATION	0.0000032	0.0001057	0.6272567	0.4841685	2.018118	90	TRIP13 DDX11 BUB1B NEK2 CCNB1 CENPF NDC80 TTK RACGAP1 PLK1 AURKB PTTG1 ECT2 ESPL1 CDC6 CDT1 SPDL1 MKI67 BUB1 TPR KIF2C MAD1L1 CDCA5 HORMAD1 MAD2L1 RAD18 KNSTRN ANAPC5 FEN1 SPAG5 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3	up	***
REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS	0.0000608	0.0012747	0.5573322	0.5325883	2.017930	52	MUC5B MUC13 C1GALT1 GALNT14 GALNT6 MUC4 GCNT3 MUC16 CHST4 MUC5AC GALNT4 GALNT10 MUC20 MUC6 GALNT9 B3GNTL1 B3GNT3	up	**
FOSTER_TOLERANT_MACROPHAGE_DN	0.0000000	0.0000000	0.9101197	-0.3479963	-2.017792	372	CXCL3 OLR1 TAL1 USP12 HHEX GLIPR2 IL1B MNDA SNX10 LRRFIP1 ENG OTUD1 PLEKHF2 SAMHD1 CAV1 KIAA1109 MYADM CITED2 PRPF38A CASP12 NR3C1 TET2 NFIX HBEGF LMNA PPP1R15B MAP3K8 LUZP1 RNF125 HDC FOXP1 PTX3 BFAR ZBTB8A AKT3 ZEB1 TUBB6 TIPARP ATP10A IL10 CSRNP1 STAT5A CCL22 PPM1K PLAUR SLC12A4 DRAM1 SOCS2 KLF7 RMDN3 SEC24B MGAT4A NFKB1 CDKN1A CXCL2 SELP HOPX CCND2 FRMD4A GCA ARL4A N4BP1 UBASH3B KPNA3 AFF1 TANC1 CMTM6 KREMEN1 SNN FMNL2 DCP1A IL6 SOCS3 SRSF3 ETV3 MTMR14 LRCH1 NOTCH1 ST6GALNAC4 HSPA1B JUNB RCAN1 CD83 PCGF5 GYPC MALT1 REL HOMER1 ZNRF3 OGFRL1 FOS HIVEP2 RIN2 TCF4 DUSP5 CTNNAL1 KHDRBS1 CD86 PIM1 GPR84 GNB4 TAGAP PDE4B MOB3B IL18 PDLIM5 SERTAD1 ADAMTS4 XKR8 SETDB2 CEBPD TIAM1 ATP9B TAB2 RIPK2 TBC1D1 ZDHHC21 TRAF1 RND1 KATNA1 FNBP4 MAFK CTSC EDN1 MTUS1 TLK2 TNFSF9 AIM2 SFPQ GSPT1 FEZ2 MIER3 DNAJA2 SPATA13 SPHK1 IRF2 JDP2 SPSB1 SERPINE1 TNFSF8 TMEM30A ATP11B ZNF800 ENDOD1 ZYX ZFP36 PLEKHA2	down	***
GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000001	0.0000035	0.7049757	-0.3804407	-2.017665	182	SMAD6 SEMA6A KMO SC5D SLC47A1 PECAM1 PPARG DCSTAMP CAT RDX THBD CCRL2 CCDC88A CYB5R3 SLC15A3 ALAS1 FUCA1 IGSF6 CD36 MAN2B1 HBEGF CD33 ANPEP ADIPOR1 ABHD6 TNS1 SLC19A1 ATP6V1H RAB14 CST3 CFD ZCCHC24 TPP1 CDKN1A ATF3 TM6SF1 CLIP4 HCK CLN8 PRCP VAMP3 C2CD2 MITF TYROBP PABPC4 CD83 APH1B PSMD12 RIN2 TIMP2 TCF4 PEA15 CTNNAL1 MCUR1 MEIS3P1 LGALS3 KYNU CCNH RXRA CPQ FKBP1A NLRP3 SCPEP1 DAPK1 BCAT1 CTSC CD1E ANXA11 EHD4	down	***
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP	0.0000000	0.0000000	1.1421912	-0.3231814	-2.016707	744	RAB11FIP1 CXCL3 SLC31A2 EREG IL1A HMOX1 SWAP70 ABHD5 PPARG SECISBP2L CD55 ATXN3 THBD BMP2 SIK1 BACH1 ST3GAL6 RASAL2 CITED2 CIR1 YPEL5 ARL8B MEF2A CDC42 RGPD5 NCF2 WBP4 TRIB1 SYNC CCNL1 ZEB2 DNAJB14 TXNIP NUMB HSPE1 KIAA0355 ATP2B1 CLCF1 RRAGC UBL3 ADAM17 EIF1 MTF1 EIF5 SERINC1 CSGALNACT2 KLF10 HIPK3 KLF6 PTX3 SLC7A11 GPBP1L1 PPP2R2A FOXJ3 TRAF6 NFE2L2 NDEL1 LAMTOR3 SPRY2 CLK1 ARHGEF2 ITSN2 TCF7L2 ATP6V1B2 TIPARP KPNA5 RHOB GMEB1 ZMIZ1 PER3 AGO3 SORBS1 KLF4 COQ10B KLF9 ANKRD10 KLF11 TJP1 STK17B MAP1LC3B TMED5 STX3 MAFG ZNF24 SPAG9 SNIP1 SEC24B PER2 RIT1 CDKN1A NR1D2 CXCL2 ATF3 PNRC1 ZBTB43 CLK4 UBE2B PLEKHB2 CCSER2 PER1 DUSP1 WDR48 BRF2 INHBA CPT1A N4BP2L1 DSE SLC6A6 N4BP1 PAFAH1B1 TP53BP2 MAFF PLCD1 NRBF2 IL24 MARK3 IKZF5 RABGGTB RSRC2 CDKN2AIP PI4K2A VCPKMT NCOA1 SNN RAB6A TOPORS ZNF426 BTG1 UFM1 RBM39 DCP1A ELF1 AREG IL6 RYBP ZNF442 PKNOX1 NSMAF COPS2 PSEN1 SNAP23 RAB8B OASL NXF1 HECA FAM189A2 VAT1 NOTCH1 HMBOX1 GABPA HRH1 CELF1 PLK3 DNAJA1 RABGAP1 RCAN1 PPP1R15A SKIL HSPA13 MBNL2 STX5 MORC3 PDZD2 EGLN2 GPRC5A IP6K1 SLC3A2 FOS ADNP2 RHOQ CDK17 PTP4A1 AZI2 HIVEP2 MBP FOXO3 TTBK2 CHORDC1 STXBP3 PHF3 JMJD6 BAZ2B OSGIN1 TSC22D1 FEM1B DUSP5 GNAI1 KHDRBS1 IRS2 DYNC1LI1 MAP3K2 PIM1 HBP1 CCDC68 SOD2 LGALS3 GABARAPL1 TOB1 ANKRD12 GNA13 N4BP2L2 RGS2 PLEKHO2 CLCN6 CSNK2A2 TCF7L1 PLA2G15 ETS2 IST1 ARPP19 GTF2B JUND GEM FGF2 IL18 ABL2 RLF ZNF143 CGRRF1 TFPI DCTN4 RAB5A CEBPD CDKN1C HSP90AA1 VPS4B USPL1 RIPK2 SIK3 EIF4EBP3 TOB2 ARIH1 UBE2D1 MEGF9 BRWD1 CREBBP OSER1 RBM48 FNBP4 CUL3 NFKBIA JMJD1C RNF38 MTUS1 LYST DNAJB9 TNFSF9 ZNF165 FGFR1 ITCH NRG1 GRB10 SFPQ WDFY3 PUM1 ATF4 SMAD4 ARFGAP3 TRIM36 PMAIP1 ZBTB40 MED17 DCUN1D2 RABGEF1 CSF2 ABI1 UBAP1 HERPUD1 SPSB1 UBR2 CHIC2 SLC25A38 GJC1 ATF2 LHFPL2 ING1 FTL RB1CC1 SLC38A2 ZFP36 YRDC CCNT2 PTGS1 DNAJB4 HEY1 SRSF11 DNAJB1 CCDC93 WAC GPR137B WDR47 TRIM13 TSC22D2 SERP1 EP300 IRF1 ATP2B4 NFIL3 MEF2D CHKA TRIM25 SETD2	down	***
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2	0.0000000	0.0000000	0.9214260	0.4161671	2.015589	359	CCNO RIBC2 PCSK6 MDM1 NGEF RPGRIP1L NEK2 ARMC3 APOLD1 STOX1 TTC25 CCDC113 SRGAP3 FANK1 CCDC74A STIL SAYSD1 TTC26 CEP70 IFT27 SAMD15 SPATS2 RAB36 COCH TMCC1 DZANK1 LRRC27 DCTN2 SLC4A8 AK8 DNAI1 RSPH1 ARMC4 SDHA PAQR4 C9orf116 FOXJ1 TSGA10 CLHC1 P4HTM ODF2 IFT43 POC1A WDR78 DPCD SPEF2 TEKT2 EFCAB12 CCDC89 CCDC114 PASK C7orf57 WDR66 PFN2 C11orf16 NME5 NEK11 MDM2 DNAAF3 HES6 SPATA17 CAPS DNAH11 C4orf47 CCDC138 CCDC40 ZNF346 GPX8 CCDC78 DRC1 TMEM106C C2orf50 PPM1E LINGO1 DNAH6 EFCAB6 ARHGAP39 STON2 MDH1B FAM81B KLHDC9 PAXIP1-AS1 NEK5 RALGPS1 KIAA1211L AK7 DNAH5 TMEM231 CASC1 FGFR1OP IFT52 C3orf67 ZNF606 DENND6B KIAA1257 SPEF1 CAPS2 BBS5 NPHP1 TRIM24 TUBG1 DNAH7 EFCAB2 PSME2 COG7 IQCG FBXO15 MORN2 IQCK HECTD1 LRWD1 SPA17 IQCH CEP128 TYRO3 TMEM232 DNAJB13 KIAA1549 AGBL2 IQUB CCDC30 EFHC1 ODF2L EML6 ZNF432 RAB15 NEK4 ZNF599 EFHB LRRK1 TTLL6 RSPH4A LRRC46 UNC119B STRBP CEP85 TTC12 SERPINI2 GBP1 CLUAP1 UHRF1BP1 ENKUR FRMD8 AIFM2 WDR49 VDAC3 TTC30B ZMYND10 E2F7 RNF32 MOK MAP3K19 NPTX2 SPATA33 DNAL4 ARMC2 PAQR8 DNAAF1 MAK TEKT1 WRAP73 WDR63 PLK4 CYTH3 MST1 SRI ROPN1L RSAD2 DZIP1 KIAA1841 AK9 XAF1 SNTN TPPP3 C1orf194 NETO2 KIF6 TMEM67 CEP112 HERC2 RMI1 CMPK2 CCDC65 C5orf49 BBS12 CEP19 KIF3A PIFO SNHG10 DNAL1 PPP1R32 IK MUC12 CIAO1 STPG1 NPHP4 ZC2HC1C NOD2 MAP6 PPIL6 DNAH12 IFT81 IFT74 AIG1 ZBBX ACTR6 ZNF200 MKX WDR92	up	***
GO_DNA_REPLICATION_INDEPENDENT_NUCLEOSOME_ORGANIZATION	0.0000920	0.0018016	0.5384341	0.6022695	2.015524	32	HJURP RUVBL1 CABIN1 CENPA MIS18A CENPL CENPW CENPO ASF1B CENPH CENPP HIRA CENPQ CENPK SUPT16H CENPM CENPT	up	**
REACTOME_REGULATION_OF_SIGNALING_BY_CBL	0.0012825	0.0154137	0.4550599	-0.5986213	-2.015144	20	FYN CBL CRK HCK RAPGEF1 PIK3R1 GRB2 UBB	down	*
GO_KINETOCHORE	0.0000007	0.0000280	0.6594444	0.4683509	2.014763	114	HJURP BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TTK PLK1 NUF2 AURKB CENPA DYNC1I1 ZWINT CDT1 DCTN2 SPDL1 BOD1 TP53BP1 KNTC1 BUB1 REC8 TPR KIF2C MAD1L1 CENPW MAD2L1 CENPO SPC24 INCENP KNSTRN CBX5 CENPH BIRC5 SPAG5 TRAPPC12 MTBP RANGAP1 KIF22 CENPQ LRWD1 NUP85 CENPK CENPV CKAP5 CENPM DYNC1LI2 CENPT	up	***
REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_OXIDATIVE_STRESS_METABOLIC_AND_NEURONAL_GENES	0.0012825	0.0154137	0.4550599	-0.5983579	-2.014257	20	ATXN3 CAT NR3C1 PLXNA4 FOXO1 FOXO3 SOD2 SMAD2 SIN3A SMAD4	down	*
REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	0.0013741	0.0162321	0.4550599	-0.7300635	-2.013901	11	FFAR4 SPCS3 TCF7L2	down	*
REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLUCAGON_LIKE_PEPTIDE_1_GLP_1	0.0013741	0.0162321	0.4550599	-0.7300635	-2.013901	11	FFAR4 SPCS3 TCF7L2	down	*
GO_CILIUM_ORGANIZATION	0.0000000	0.0000000	0.8390889	0.4218672	2.013874	304	CCNO PKHD1 MCIDAS ONECUT2 ONECUT1 CEP72 CEP89 RPGRIP1L NEK2 AVIL NUDCD3 RAB3IP MKS1 CCDC113 STK36 IFT122 SPAG17 TTC26 CEP70 PLK1 IFT27 KIF27 DCTN2 WDR90 DNAI1 HAUS5 CEP250 RSPH1 ARMC4 BBS1 SPAG16 FOXJ1 KIF3B CCDC13 FBF1 ODF2 SFI1 IFT43 POC1A HYDIN TEKT2 CCDC114 DCDC2 WDR60 NME5 DNAH8 IFT172 GAS8 KIF3C CBY1 DNAAF3 RABEP2 C2CD3 CCDC40 DRC1 LRGUK LRRC6 IQCB1 CDK1 CROCC CEP97 CENPJ VANGL2 KIF19 TCTN2 SSX2IP DYNLL2 POC1B LCA5 DNAH5 TMEM231 FGFR1OP IFT52 CEP63 BBS5 CEP192 NPHP1 TUBG1 DNAH7 NINL MNS1 CCDC151 IQCG TMEM237 SPAG1 TEKT3 TRAF3IP1 DNAJB13 CKAP5 IQUB ROPN1B WDR34 TTLL3 TCTN1 CDK5RAP2 ODF2L DNAI2 WDR35 HAUS6 DYNC2H1 FAM161A TBC1D30 HAUS4 RSPH4A TCHP UNC119B CEP152 TMEM17 B9D1 ALMS1 ICK CEP164 CLUAP1 DNAH1 MARK4 CELSR2 TBC1D32 TTC39C VDAC3 UBXN10 CELSR3 SYNE2 TTC30B ZMYND10 CLASP1 KIF24 KIAA0586 CEP290 ARMC2 DNAAF1 DYNC1H1 MAK TEKT1 ABLIM3 WRAP73 WDR63 PLK4 AKAP9 PCNT	up	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_UP	0.0000001	0.0000055	0.7049757	-0.3843341	-2.013436	157	SC5D PGC GPR65 SIK1 HSD17B11 OTUD1 SAMHD1 CITED2 ELF2 YPEL5 AGTPBP1 BTG2 SPTBN1 PDE4D TCF7L2 ITPRIP AHNAK SGTB KLF4 COQ10B DENND3 KLF7 C9orf72 DUSP1 RNF139 UBASH3B MYH11 PIK3R5 MAFF C16orf54 PKIG MYLIP SGK1 SOCS3 SNX29 MAP4K4 JUNB ATXN1L SKIL PNPLA8 FOS YPEL2 BIN2 ADPRM FAM228B TSC22D1 IRS2 RELL1 KCNA3 TOB1 RGS2 KAT2B HAUS3 BNIP3L CCDC69 EPHA4 BRWD1 TTC32 OSER1 ING2 SIN3A DNAJB9 ITCH ZFAND2A	down	***
GO_CHROMATIN_REMODELING_AT_CENTROMERE	0.0000550	0.0011683	0.5573322	0.6350120	2.012997	26	HELLS HJURP RUVBL1 CENPA MIS18A CENPL CENPW CENPO CENPH CENPP CENPQ CENPK CENPV CENPM CENPT	up	**
GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN	0.0000001	0.0000053	0.7049757	-0.3824009	-2.012112	168	CXCL3 KMO CD55 HHEX MKNK1 ZEB2 UBL3 ASAH1 SERINC1 MAP3K8 ABCG1 GLS HLX TOR1AIP1 TRAF6 ZFYVE16 FBXL5 EFCAB14 KLF7 DOCK9 CXCL2 SMAD7 GCA CRIM1 HCK RPS6KA2 MOB4 MYO1C ARL6IP5 VAMP3 PSEN1 MAGI2 RABGAP1 IFNGR1 STX7 IFRD1 KLHL18 MORC3 RPS6KA1 GRSF1 YTHDF3 BAZ2B VAMP4 MIA3 GALC HBP1 TERF2IP FCGRT STX12 SBSPON N4BP2L2 CLCN6 ATAD2B ARAP2 CEBPD ESYT1 METTL7A DAPK1 CD19 RASSF8 LYST CYTH1 DOCK4 IL16 RNF13 EVI5 FEZ2 LYZ SETX FAM8A1 ZFP36 CD69 C6orf62 MTSS1 TRIM13	down	***
GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN	0.0000001	0.0000069	0.6901325	-0.3790061	-2.011701	180	CXCL3 EREG KMO TSPAN4 DENND5A IL1B ADCY9 CDH5 FYN CITED2 BCL2A1 FAM49A OLFML2A MTF1 MAP3K8 RNASE1 PTX3 IL18R1 CRK ARHGEF2 MAP2K3 STAT5A CPVL SLC7A8 THBS1 CXCL2 DNTTIP2 IL7R TP53BP2 MARK3 BTG1 RPS6KA2 SERTAD2 KANK1 TECR IL6 BCAR3 UTRN MITF CTSZ MAP4K4 WTAP PTGER4 IRF8 GYPC AGFG1 PTP4A1 YTHDF3 SRSF6 RIN2 TIMP2 EHD1 UTP3 CCL20 GEM ICAM1 ANKLE2 CPQ WDR1 CDC42EP3 VPS4B NLRP3 TRAF1 DAPK1 BCAT1 ADORA2A	down	***
GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_DN	0.0000000	0.0000015	0.7337620	-0.3782248	-2.011214	176	CLIC3 PECAM1 CTSW TGFBR3 RFTN1 ABCB1 CD8A ZEB2 PTS CACNA2D2 C1orf21 BZW1 MAP3K8 LITAF KLF10 PPP3CA ADRB2 CRTAM TIPARP MAP2K3 FABP5 YBX3 MVB12B FAM49B ITPK1 HOPX ID2 CCL4 PRF1 SMAD7 PLEK ADIPOR2 KLRD1 MATK SH2D2A MAFF CRIM1 PROCR CD8B SAR1A CD160 IL2RB IDS LSM1 GTDC1 HOMER1 TBX21 CST7 UBB MFSD10 RUNX3 NKG7 JMJD6 GATA6 SYT11 PIP4K2A PTCH1 KLRK1 LYST MT2A IQGAP1 KLRF1 CHP1 CX3CR1 AOAH ITGAL MT1E CALR	down	***
GO_MICROTUBULE_ASSOCIATED_COMPLEX	0.0000004	0.0000148	0.6749629	0.4563884	2.011168	135	KIF1A KIF12 KLC3 KIF20A DNAH2 KIF18B NUDCD3 KIF14 CDCA8 AURKB DNAH3 DYNC1I1 KIF27 DNAH14 DCTN2 DNAI1 HAUS5 MAP7 KIF23 KIF15 KIF3B AURKA TPR KIF2C WDR78 CCDC114 KIF11 WDR60 DNAH8 KIF3C DNAH11 FNTB TTBK1 DRC1 DNAH6 KIF5A SNX4 BIRC5 KIF19 KIF2A KIF7 DYNLL2 DNAH5 DNAH7 KIF22 KIF21A KIF20B KLC2 KLC4 WDR34 DYNC1LI2 KIF21B DNAI2 HAUS6 DYNC2H1 KATNB1 HAUS4	up	***
GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_DN	0.0000000	0.0000013	0.7337620	0.4433604	2.009123	175	BDH1 FANCI BUB1B CENPF GGCT TTF2 SORD PHGDH TTK GINS1 CDK4 SLC27A2 TRAIP NIPSNAP1 PLK1 AURKB ESPL1 GAPDH MCM4 MCM2 TYMS UMPS MYBL2 ORC1 CCT6A SHMT2 XPOT NCAPD2 ZWINT MELK NDUFB8 HMMR CHAF1A EEF1E1 TOP2A AURKA RAD54L PKM MCM3 RAD51AP1 BLM IDH2 PARP1 THOP1 CKS1B UNG EZH2 MRPS12 FADD ST14 TUBG1 FAH PSMA5 SNRPA CDC7 PFAS AHCYL1 MRPL28 FAM161A HAX1 SLC1A5 NEFH GOSR2 AP2S1 PYCR1 PRIM1 ECHS1 TMED9 CPOX MTHFD1 TP53 PCBD1 SNRPC BCAT2 ENO1 CYB5B SRM BAG2 PLK4 GSTP1 ADSL TOMM40 PMVK CRYZ	up	***
GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000000	0.0000024	0.7195128	-0.3781211	-2.008545	179	MGAT3 ABHD5 PECAM1 CD55 FBP1 LMO2 CCDC88A P2RY13 FUCA1 WBP4 RHOA SH2B3 NDUFAF1 CD33 SERINC1 PBX3 CAV2 ADIPOR1 SPTBN1 CLK1 ZFYVE16 ATP6V1B2 ROCK2 TLE4 SDCBP FAM124B OSTF1 DENND3 SOCS5 CXCL2 TM6SF1 ALOX5AP CCDC59 TM9SF2 NRBF2 LMBRD1 ZCWPW1 VAMP3 FRY WASF2 PHTF2 ADAMTSL2 CRNKL1 PIKFYVE JAK1 PSTPIP2 TINF2 NDUFV2 PSMD12 BTBD7 CHPT1 SRSF4 MILR1 PIK3C3 PIM1 HBP1 PLAA SERINC3 ARPC2 LMOD1 LRP12 CYB5R4 OSER1 MARC1 NFU1 ANXA11 C21orf91 CREG1 EID1	down	***
GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP	0.0000001	0.0000041	0.7049757	-0.3785622	-2.007702	182	IL1A SWAP70 SOWAHC EGR2 CD44 VAMP2 YPEL5 ZBTB2 CCNL1 ADAM17 ANXA5 ZBTB21 KLF6 PTX3 FOXJ3 NR4A1 MED26 NFE2L2 HNRNPDL LAMTOR3 PPP1R13B ZEB1 BTG3 UBE2D3 CSRNP1 MOAP1 DUSP3 COQ10B CDIP1 KLF7 ATF3 DUSP11 JAM2 UBE2B DUSP1 RPF1 PIK3R5 MAFF ANXA3 ZNF330 ETF1 MAP4K4 HSPA1B SHOC2 TBC1D12 PPP1R15A GLIPR1 THUMPD1 ZNF597 RNF24 ADNP2 IRS2 WBP2 GNA13 ETS2 ICAM1 C3orf38 ABL2 SERTAD1 IER5 RTN4 THAP6 MEX3C EPHA2 RASSF8 MAFK MRPL32 GNMT TLK2 PAIP2 SMAD4 PIM3 YTHDC1 CFL2 TMEM43	down	***
GCM_CSNK1A1	0.0001674	0.0029610	0.5188481	-0.5334268	-2.007239	34	SEC22C ARL8B OTUD4 PPP1R15B FOXJ3 TOR1AIP1 FBXL5 RSRC2 DHX15 TMEM167B OCIAD1 GNA13 C1orf52 MED17 HIPK1 SENP6 EIF3J ANKRD17 PRPF8 YME1L1 PCNP RBM25	down	**
GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	0.0000000	0.0000014	0.7337620	0.4448992	2.006558	169	CEP72 CDC45 TICRR POLQ KIF18B BRCA1 ECE2 E2F8 CDCA8 AURKB ACAD9 SLC6A3 FIGNL1 MCM4 MCM2 EIF3B MIS18A CCDC150 NLE1 DPY19L2P2 RHNO1 POLD2 GPSM2 CHAF1B BRI3BP BLM CCDC136 PSRC1 NCAPG2 DDX51 MRPL37 SERTAD4 ATIC UNG MRPS2 FEN1 SSX2IP ACTR3B SPAG5 SNRNP25 MYO19 TUBG1 DHODH SLC37A4 UBE3D DOK4 DTYMK HDAC1 TJAP1 NRF1 NUP85 KLHL32 GPATCH4 POP7 MCM6 MALSU1 DDX23 LTV1 EXOSC5 STK39 AP4B1 WDYHV1 GLO1 CISD3 CCDC167 ZWILCH MRPL9 LLPH TARBP2 MTHFD1 SEPHS1 CHERP	up	***
GO_COPULATION	0.0012160	0.0147946	0.4550599	-0.7165487	-2.006158	12	SLC6A4 EDNRB P2RY1 DDO ADA	down	*
GO_ANGIOGENESIS_INVOLVED_IN_WOUND_HEALING	0.0012481	0.0150775	0.4550599	-0.5775681	-2.006001	22	FOXC2 GPR4 HPSE ADIPOR2 SRF PRCP NDNF ETS1 MCAM CD34 CXCR4 SERPINE1	down	*
GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	0.0000001	0.0000028	0.7195128	-0.3784385	-2.004956	173	SC5D ABHD5 RAPGEF2 INPP5K S1PR1 ANXA1 ASAH1 BTG2 MAP3K8 SRSF2 TCF7L2 CSRNP1 MTMR6 MOAP1 ITPRIP FOXO1 PSTK COQ10B LEPROTL1 DUSP11 CD302 DNTTIP2 UBASH3B PIK3R5 MIR17HG IKZF5 TMEM9B CCNY DDX20 NXF1 HECA ETV3 NOTCH1 PTGER4 PIK3R1 TPP2 OGFRL1 ZNF350 ADNP2 PELI1 SRSF6 TRAPPC10 NAP1L5 AZIN1 VAV3 TCF4 SMCR8 ADPGK KTI12 GTF2B IQSEC1 CXCR4 USPL1 TXNDC11 TMEM184B SOAT1 NFKBIA JMJD1C RNF38 TTC19 ZNF791 DNAJB9	down	***
GO_MITOTIC_NUCLEAR_DIVISION	0.0000000	0.0000003	0.7749390	0.4275128	2.004658	237	TRIP13 SPICE1 CHEK2 BUB1B NEK2 CCNB1 CENPF KIF18B NDC80 TTK SMPD3 RACGAP1 KIF14 L3MBTL1 ANLN MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 TPX2 MYBL2 PRC1 NCAPD2 ZWINT CDT1 SPDL1 RANBP1 KIF23 MKI67 CUL9 BOD1 CUL7 KNTC1 KIF3B BUB1 MAP10 AURKA TPR KIF2C MAD1L1 CDCA5 TOM1L1 KIF11 CDC25C CHEK1 MAD2L1 DSCC1 PKMYT1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 CEP97 BIRC5 DIS3L2 NCAPG KIF2A SPAG5 EGF MTBP MAD2L2 KLHL22 KPNB1 CEP192 CDC23 TUBG1 DLGAP5 TACC3 KIF22 HIRA AKAP8L KIF20B ANAPC1 CDK13 CENPK SH2B1 CDC20 TUBG2 AAAS CHMP4C CDK5RAP2 CHTF8 KATNB1 RCC1 PRMT5 NUP62 CEP85 CHMP1A CHMP2A AURKAIP1 SMC2 MAU2 CENPE GOLGA2 UBE2C NCAPD3 MAP9 RRS1 CLASP1 NCAPH POGZ CHMP6 PDXP DRG1 WRAP73 DSN1 FBXO5 LCMT1 NFE2L1 NSL1 MAD2L1BP	up	***
SHEN_SMARCA2_TARGETS_UP	0.0000000	0.0000000	0.9101197	-0.3465402	-2.003838	391	OSBPL1A RDX MED4 KIAA1109 YPEL5 PRKAR1A FBXO3 TMX4 NUMB ARHGAP29 KIAA0355 UBL3 SERINC1 TOR1AIP1 RB1 TMEM41B ITSN2 RAB14 FBXL5 EFCAB14 HNRNPA3 PRKD3 ROCK1 SEC24B CEP57 ACTR3 CAPZA2 PPP2R5C CUL5 GNAQ PAFAH1B1 BCLAF1 LMBRD1 COPS4 HSDL2 RSRC2 NCOA1 RAB6A KANK1 MOB4 RBPJ PRKRA COPS2 RBM34 NEK7 CUL4A C11orf58 OSTM1 SHOC2 RABGAP1 VPS26A SNX2 FBXO11 STX7 SP3 SDHD IDS RBM22 TRAK2 UVRAG NOL7 RALB TUBGCP3 RNF146 MORF4L1 PSMD12 ATG3 ZFAND6 STXBP3 PHF3 BAZ2B CRYZL1 DPM1 FEM1B ZCCHC10 TMEM230 NAB1 NFYC ATXN1 HNRNPH3 EXOC1 STON1 NPTN MACF1 SERINC3 SMAD2 CHMP3 DCTN4 SEC63 MTO1 CALCOCO2 TAB2 POLR2M SRSF10 ISCU RBM48 STAM2 LIMCH1 COPS8 RNF38 NFU1 DAZAP2 TRAPPC11 RHOT1 CREG1 TLK1 WDFY3 EID1 SMAD4 RAB2A HAT1 YTHDC1 ABI1 SETX UBR2 CDKN1B AKTIP CENPC HIPK1 SSB TGOLN2 TRMT1L FBXW2 NDFIP1 PPWD1 UNC50 KIDINS220 CTR9 MATR3 ANKHD1 PCMT1 CUL2 SMARCA5 RAB1A ORC4 SRP14 BBIP1 UFSP2 CAPN7 PJA2 NFYB SKP1 SCAF8 VPS13C LARP7 MRPS14 DENND4C SENP6 SON PUM2 ZC3H7A SUCLA2 NSMCE4A ISCA1 AASDHPPT FEM1C LEPROT TANK SOS2 EED TMEM126B ANKRD17 RNF130 SEC62 PRPF38B AKAP11 APPBP2 TNPO1 SLC25A46 PCNP NUDT21 XPA PSMG2 CD59 RAB7A RIOK3 PPP1R2 SNX5 TMEM135 SMAP1 ARFIP1 OSBPL8 RWDD3 TMED10 ZC3H15 MRS2 SOCS6 DCP2 SMC5	down	***
DIRMEIER_LMP1_RESPONSE_LATE_UP	0.0001021	0.0019718	0.5384341	-0.4765204	-2.003447	49	HMOX1 OTUD4 RFTN1 BZW1 LITAF SERPINB9 CD58 STAT5A CCL22 NFKB1 PLEK ETF1 RHOG RUNX3 IRF5 NBN SPIB TRAF1 FEZ1 PIEZO1	down	**
GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN	0.0000001	0.0000045	0.7049757	-0.3777164	-2.003217	182	HMOX1 IL1B MIR22HG INSIG1 FYN TRIB1 LMNA BTG2 KLF6 RNASE1 PTX3 HLX SLC7A11 LAIR1 RBM4 SRSF2 MAP2K3 SLC7A8 VASP THBS1 CCL3 NFKB1 CDKN1A RBMS1 CCL4 IL7R TP53BP2 SNN EMP3 RPS6KA2 SERTAD2 KANK1 TECR CREM OASL SERPINB8 SH3BP5 CTSZ MAP4K4 PPP1R15A WTAP PTGER4 FERMT2 IRF8 TCP1 TNFRSF9 YWHAZ DENND4A CLN3 SLC3A2 ATP6V0D1 PTP4A1 HIVEP2 TIMP2 TEX30 DUSP5 PIM1 APLP2 CCR1 GEM ICAM1 ABL2 CPQ CGRRF1 TRAF1 S100A4 BCAT1 DOCK10 PMAIP1 SERPINE1 TNFSF8 FUS ABHD14A DNAJC8 MTSS1 MAN1A1 IRF1 ATP8A1 TRIM25 MSC KRT10 DUSP2 RNF19B EMP1 PNP ADAM19 TNFRSF1B ZFHX3 EIF4A3 EZR C15orf39 CD47 PRPF4 APBB3 VNN2 TGFBI STX2 IFIT3 IFIT2 TUBB4B TNFAIP2 RGS16 ELL2 PHLDB1 PMP22 P2RX7 FCGR2A UAP1 RGS1	down	***
LE_EGR2_TARGETS_UP	0.0000080	0.0002312	0.5933255	0.4734955	2.001416	96	HMGA2 KIF20A CCNB1 SOX2 UBE2T IQGAP3 PLK1 CDCA8 ECT2 CCNB2 FIGNL1 UHRF1 MCM4 PRC1 TNC BZW2 KIF23 MKI67 BUB1 TOP2A AURKA KIF2C MCM7 RRM2 KIF11 LMNB1 DNAJC9 MAD2L1 INCENP CKS1B CXCL14 NUSAP1 CDK1 TNFRSF21 BIRC5 NAV2 EZH2 KIF22 SLC22A23 MARCKSL1 CDC7 CDC20 MCM5 MARCKS NT5DC2 CCNA2 RFC5 RAD51	up	***
GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000001	0.0000035	0.7049757	-0.3833925	-2.001370	158	ACVRL1 CPEB2 CDH5 HCAR2 CALCRL YPEL5 FAM49A ZEB2 UBL3 CD33 CYB5A MAP3K8 PICALM MS4A14 ITSN2 PPP3CC ARRB1 AHNAK PLAUR PXDC1 ZADH2 CEBPA FMNL3 UBE2E2 HPSE FRMD4A N4BP2L1 HES1 USP25 SCEL PSEN1 SOCS3 IL2RB UTRN SERPINB8 RAB31 KCTD12 PDE5A RHOG ENPP4 EGLN2 PXK NDST1 NKG7 RIN2 FCGRT KYNU IL18 PIP4K2A ORMDL1 SP100 S100A4 THEMIS2 GIMAP4 SMAD4 RNF13 EHD3 FCRL1 ABI1 CTSH ICOS RNF167 MICAL1 SGIP1 NMI STARD5 SLC25A45	down	***
GO_POSITIVE_REGULATION_OF_SPROUTING_ANGIOGENESIS	0.0002233	0.0037716	0.5188481	-0.4944081	-2.001287	39	HMOX1 GATA2 BMPER MIR27B ANXA1 MIR146A ITGA5 AKT3 FOXC2 IL10 KLF4 PIK3C2A JAK1 RHOJ	down	**
chr3p13	0.0007711	0.0103928	0.4772708	-0.6347381	-2.000456	17	RN7SL418P FOXP1 RNU2-64P LINC00877 MIR1284 RYBP FOXP1-IT1 MITF	down	*
GO_TERTIARY_GRANULE_MEMBRANE	0.0001185	0.0022216	0.5384341	-0.4561131	-1.999508	57	OLR1 CLEC12A PTPRB SLC11A1 CD33 STOM LAIR1 SIRPA CD93 LAMTOR3 RAB14 PTAFR GAA ITGAX CD53 FCER1G HGSNAT SNAP23 ATP11A SERPINB6 SIGLEC14 FPR2 TSPAN14 ATP6V0C GPR84 ADAM10	down	**
LIEN_BREAST_CARCINOMA_METAPLASTIC_VS_DUCTAL_DN	0.0000042	0.0001355	0.6105269	0.4760089	1.998452	93	BIK ZG16B EPN3 DNAJC12 PLEKHA6 TTC39A SPDEF TFF3 CREB3L4 ZFP62 PRR15L LAMP5 AGR2 SPINT2 CA12 COX11 RSPH1 FOXA1 BPIFB1 IFI44L AP1M2 NME5 SLC9A3R1 GRHL2 MB KRT18 SERTAD4 ABCC11 REEP6 KLHDC9 HID1 KRT19 FXYD3 ESR1 MYO5C LRRC17 OVOL2 ZDHHC11 ZSCAN16 EPCAM CDH1	up	***
COLDREN_GEFITINIB_RESISTANCE_DN	0.0000000	0.0000013	0.7337620	0.4332985	1.998426	199	GPR87 KLC3 HS3ST1 BIK WFDC3 LAD1 EPN3 CYP2J2 PRR15L ANKRD22 AGR2 LSR GRHL3 PLEKHA7 KCNMB4 MARVELD3 KRT15 EPS8L1 C6orf132 TJP3 LAMC2 STAP2 SMAGP SYNE4 TTC22 AP1M2 RIPK4 B3GNT3 SPINT1 MST1R CAPS EHF DDR1 GRHL2 MBOAT1 CLDN9 CAPN8 EPHA1 ADAP1 PEG10 CDH3 RAB11FIP4 SLC44A3 KIAA1211L CCDC57 TSPAN1 IRF6 KANSL1-AS1 ST14 ADAM28 S100A16 MAPK13 ZNF468 GALNT3 SMIM22 KRT19 ELMO3 FXYD3 PRRG2 TMEM30B LIMA1 ERBB3 ANXA9 SLC35A3 OVOL2 STK39 TMEM45B TC2N DOK7 PRSS8 FAM3C CDH1 TMC5 GRHL1 PRSS22 MROH1 LRG1 WLS ENPP5 ZNF91 RHOD CGN RAB25 KIAA1522 FGFBP1 ZNF681	up	***
SMID_BREAST_CANCER_LUMINAL_A_DN	0.0002052	0.0035117	0.5188481	0.7295735	1.997961	15	CDC45 NDC80 KRT16 CDCA8 TPX2 MYBL2 TTLL4 TOP2A CCNE1 ANP32E CDC20	up	**
MODULE_84	0.0000000	0.0000000	0.9759947	-0.3394330	-1.997893	449	SLPI ACP5 CD52 MS4A7 FCN1 CXCL16 OLR1 TSPAN4 PECAM1 IL1B FABP4 MNDA CLEC3B CYP27A1 GPR65 PTPRE LIPA RAMP2 TRPV2 ENG LMO2 CAV1 AQP9 CHIT1 STX11 MAL MARCO BCL2A1 NCF2 IL1RN CD22 EPB41L3 TGFBR2 IGSF6 LILRB3 HSPG2 CD8A FGR DNASE1L3 PDE2A APOD ANXA1 PLA2G7 MAN2B1 BMP1 SLC7A7 IFI30 ANPEP RNASE1 SLC7A11 LCP1 STOM LAIR1 GRN CES1 SRGN ADAMTSL4 APOC1 CD37 KRT4 GMEB1 EVI2B CFD CASP1 TNFSF12 CPVL DAB2 SLC7A8 STK17B CLDN5 PLBD1 CCL3 LAPTM5 CDKN1A PTPRC SELL CCL4 CD302 PNRC1 IGFBP2 CCND2 M6PR CD53 PRF1 FCER1G PER1 ALOX5AP PLEK EVI2A N4BP2L1 IL7R MYH11 HLA-DQA1 CRIM1 VWF ARHGDIB HCK NINJ1 EMP3 KCNA5 CD8B S1PR4 IL6 CTSS IL2RB SLCO2B1 CD48 STAT4 RAB31 HK3 RAC2 ST6GALNAC4 TYROBP JUNB IFNGR1 CSTA IRF8 GMFG GFPT2 CST7 CELF2 ACSL1 RUNX3 NKG7 CD74 MME TIMP2 SFTPC CD6 FPR2 LRRC32 CD86 LGALS3 ORM2 CCR1 FCGRT KYNU PLEKHO2 CLEC2B PDE4B TAGLN ICAM1 SELPLG GPX3 TNFAIP8 SEMA4A SPIB MS4A4A CXCR4	down	***
GO_DNA_REPLICATION	0.0000000	0.0000004	0.7614608	0.4253872	1.997360	240	MCIDAS DDX11 CDC45 TICRR MCM10 CHEK2 TIMELESS POLQ PRIM2 PIF1 BRCA1 GINS1 E2F8 DBF4B POLE CDC6 RBBP8 MCM4 MCM2 ORC1 DTL MCM8 LIG3 GINS4 CDT1 EXO1 CHAF1A RHNO1 EME1 POLA2 ATR POLD2 SMARCAL1 MCM7 CLSPN RRM2 MMS22L WDHD1 HELB MCM3 CHAF1B EGFR LIG1 EME2 TOPBP1 CHEK1 ORC6 DSCC1 BRIP1 REPIN1 BLM RECQL5 POLN ING4 CDK1 SSBP1 POLE2 DTD1 RFWD3 GMNN KCTD13 DNA2 FEN1 RECQL4 RNASEH2A CCNE1 DNAJA3 POLL RAD9A SSRP1 CHTF18 ESCO2 GINS2 LRWD1 POLD1 POLB ATAD5 SLX4 NT5M CDC7 RAD50 SUPT16H STOML2 FAF1 HMGA1 RPA1 FANCM MCM6 MGME1 CHTF8 WRNIP1 MCM5 ZRANB3 GINS3 IGHMBP2 CCNA2 PRIM1 RTEL1 RFC5 NUGGC RAD51 PNKP TONSL BCL6 E4F1 TP53	up	***
GO_POSITIVE_REGULATION_OF_INTERLEUKIN_6_PRODUCTION	0.0001390	0.0025322	0.5188481	-0.4420773	-1.996766	65	EREG IL1A SCIMP SIGLEC16 IL1B LPL MYD88 IL1RN CD36 CLEC7A TRAF6 ARHGEF2 PTAFR TLR4 FCER1G IL17D IL6 TYROBP MBP CD74 AKIRIN2	down	**
GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0000000	0.0000020	0.7195128	0.4427254	1.996754	169	TRIP13 KIF20A ASB4 PARPBP TROAP CHEK2 BUB1B NEK2 IGF2BP3 UBE2T CPSF6 KIF18B GAL3ST1 ZP3 GINS1 CDCA2 CDK4 ANLN POLE STIL IFT27 PTTG1 ECT2 E2F3 UHRF1 HOXB7 LSM5 EXO1 KCNN4 SMAGP CENPL PCDHGC4 RAD54L KIF11 FANCD2 CDC25C PFN2 PYCR2 LIG1 ORC6 MSI1 DSCC1 PPIL1 KNSTRN NCAPG2 CDKN2C FAM135A GMNN UNG NCAPG IGHG1 CENPP PA2G4 SPEF1 CCNE1 ESCO2 PKP4 ASNS NT5M CENPK CENPV TMCO4 SMIM6 C5orf22 C1orf122 ALG8 JAKMIP3 CCNA2 PRIM1 PRR11 ACKR2 RAD51 ZWILCH ARHGAP11A MXD3 VDAC3 SLC12A2 RASGRF1 ANKMY2 NEIL1 TMEM256 LXN ERLIN1 NCAPH TFB1M RTN4IP1	up	***
WANG_IMMORTALIZED_BY_HOXA9_AND_MEIS1_DN	0.0009316	0.0120311	0.4772708	-0.5841733	-1.996673	21	LY86 CALCRL ERG CD93 IL7R CD34 TSC22D1 MEIS1	down	*
REACTOME_RUNX3_REGULATES_NOTCH_SIGNALING	0.0013983	0.0163977	0.4550599	-0.7130687	-1.996415	12	HES1 RBPJ MAML2 NOTCH1 RUNX3 KAT2B CREBBP SNW1 EP300	down	*
GO_MITOCHONDRIAL_GENE_EXPRESSION	0.0000004	0.0000167	0.6749629	0.4478837	1.995987	146	TSFM TBRG4 MRPL46 SHMT2 MRPS35 UQCC1 AARS2 MRPL15 LARS2 ERAL1 MRPL3 MRPL27 TARS2 SARS2 TRMT61B MRPS11 MRPS30 MTG1 TRIT1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 UQCC2 COA3 PUS1 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 ELAC2 YARS2 IARS2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 CDK5RAP1 GADD45GIP1 MTIF3 MRPL9 MRPL21 AURKAIP1 EARS2 MRPS27 MRPL20 MRPL48 MRPS26 TRUB2 MTG2 RPUSD3 POLRMT MRPS16 PPARGC1B MRPL12 MRPL43 FASTKD3 MRPL2 TEFM MRPS6	up	***
NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_DN	0.0000686	0.0014058	0.5384341	-0.4438430	-1.995599	64	GPD1 RBP4 SEMA3G PPARG FABP4 CLEC3B LPL APOD CD36 FZD4 PTX3 SFRP1 CES1 CFD AOC3 CEBPA CLDN5 ITIH5 PTGER3 PDK4 SELENBP1 NPR1 PALMD FOSB GPX3 LMOD1 ACACB METTL7A MARC1 RAPGEF3 ABCA8 C1orf115	down	**
GO_PHAGOCYTIC_VESICLE	0.0000048	0.0001505	0.6105269	-0.3985936	-1.994346	110	RAB11FIP1 MCOLN1 SCIMP HVCN1 CDC42EP2 CDC42 NCF2 LAMP1 SLC11A1 CD36 RILP RAP1A RAB14 RAB12 MPEG1 VIM ATP6V0D2 ANXA3 SNX3 MYO1C VAMP3 INPP5B SNAP23 APPL1 RAB8B RAB31 RAC2 ATP6V0B RAPGEF1 RAB8A UNC13B UVRAG ATP6V0D1 STXBP3 PIK3C3 ATP6V0C STX12 SYT11	down	***
GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN	0.0000001	0.0000069	0.6901325	-0.3832579	-1.994213	154	USP12 RASAL2 PRAM1 INPP5A CTDSP1 GAS6 ARHGAP29 ANXA1 WWC2 MAN2B1 LIFR LATS2 EIF1 CLEC14A CYYR1 HSPB1 JAM3 TNS1 CD93 CRK CDADC1 UBTD1 FMO2 ID3 THBS1 ADAMTS9 MYO1B ATF3 DSE TDRD7 TOPORS PDK4 MYLIP PRKRA SLC25A25 SGK1 MAGI2 PDE5A ARHGEF10 GPR141 RCAN1 KLRC2 C19orf38 DUSP5 GNAI1 LRRC32 TOB1 NBEAL1 PGGT1B TAGLN IL18 ORMDL1 ULK2 KLRK1 CECR2 NDUFAF5 FEZ2 KALRN DUSP6 RB1CC1 GNG11 AKAP12 ATP8A1 TNFSF18	down	***
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_UP	0.0000000	0.0000011	0.7337620	-0.3684284	-1.993278	200	RAB11FIP1 CXCL3 IL1A CXCL16 OLR1 ZC3H12C IL1B BMP2 NEDD4L BCL2A1 IL1RN IL23A DNAJC3 B3GNT5 HBEGF BTG2 KLF6 GLS PTX3 PAG1 ZNF697 CLN5 SERPINB9 SLC7A2 MAP2K3 TLE4 BIRC2 PTAFR PLAUR DRAM1 NFKB1 CDKN1A CXCL2 ATF3 IRAK2 PNRC1 INHBA DSE CLIP4 N4BP1 IL7R MAFF LACC1 BTG1 NINJ1 HCAR3 SGK1 PSEN1 SOCS3 OASL RWDD1 RASSF10 ETS1 IFNGR1 RCAN1 ELOVL7 CD83 TNFRSF9 TNFRSF10B SNX9 PELI1 EHD1 GSAP SERPINB1 KYNU ANKRD12 CCL20 ICAM1 TNFAIP8 RIPK2 TRAF1 NFKBIA EDN1 CYTH1 ZNF165 TMCC3 DOCK4 LPAR6 TNFRSF10D HERPUD1 SPSB1	down	***
AFFAR_YY1_TARGETS_DN	0.0000000	0.0000009	0.7477397	0.4296683	1.992092	205	TSPAN8 MMP13 FOXM1 HELLS KIF20A MYCBPAP ELOVL6 BUB1B CCNB1 CENPF TTK RACGAP1 NIPSNAP1 SPP1 ASPM PLK1 AURKB CENPA ALDH18A1 CDC6 SFXN1 CCNB2 TRIB3 UHRF1 MCM4 SLC4A4 PRC1 LIG3 CDT1 HMMR EXO1 KIF23 MKI67 BUB1 TOP2A AURKA THBS4 KIF2C MCM7 TMEM45A KIF11 MCM3 LMNB1 CDC25C LIG1 RIPK4 MAD2L1 STEAP4 RAD51AP1 RAD18 FADS2 IGFBP5 CENPH BIRC5 UNG NCAPG STEAP1 GJB3 FEN1 SPAG5 DIAPH3 LGR5 SLC35C2 TACC3 TUBB2A KIF22 MRPL52 TK1 CHTF18 ANP32E IGHM SPA17	up	***
chr17q21	0.0000000	0.0000006	0.7477397	0.4285755	1.990745	212	HOXB-AS3 MYCBPAP EPN3 HOXB6 KIF18B TTC25 BRCA1 PRR15L DBF4B UBE2Z SNF8 KRT16 CDC6 NBR2 HOXB7 RUNDC3A CDK5RAP3 KRT15 GSDMB NME1 RND2 TOP2A EME1 FAM171A2 CACNA1G COASY CHAD MRPL27 ACSF2 ASB16 SLC25A39 LRRC37A4P PHB HOXB5 MEOX1 OSBPL7 NSF ZNF652 RAPGEFL1 LRRC37A2 CBX1 ITGA2B DNAJC7 KANSL1-AS1 KPNB1 EFTUD2 MAP3K14-AS1 G6PC3 PLEKHM1 COL1A1 TUBG1 DCAKD COA3 AARSD1 XYLT2 NGFR ACBD4 LRRC37A17P TAC4 SPATA32 RPS7P11 KRT19 ETV4 NAGS LINC00910 VPS25 TUBG2 TNS4 LRRC59 ACLY ABCC3 MED24 DHX8 SNX11 SKAP1 TTLL6 LRRC46 GOSR2 NME1-NME2 MAP3K14 ARL17B NBR1 RSAD1 RUNDC1 MRPS21P9 HOXB2 TMEM101 NMT1 DND1P1 COPZ2 UBTF KRT17 SPATA20 KRT8P34 KCNH4 HEXIM2 LUC7L3 MBTD1 SCRN2 ASB16-AS1 PDK2 SP6 UTP18 PNPO NFE2L1 GJD3	up	***
GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY	0.0001529	0.0027470	0.5188481	0.5337494	1.990648	48	KIF1A DNAH2 KIF18B KIF14 DNAH3 DYNC1I1 DNAH14 DNAI1 KIF3B WDR78 KIF11 WDR60 DNAH8 DNAH11 DNAH6 KIF5A KIF19 DYNLL2 DNAH5 DNAH7 KIF20B WDR34 DNAI2 DYNC2H1	up	**
DALESSIO_TSA_RESPONSE	0.0025172	0.0255437	0.4317077	-0.6524938	-1.990409	15	STXBP6 ANXA1 SNAI1 ATF3 ARC PPP1R15A FOS TEX14	down	*
DANG_MYC_TARGETS_DN	0.0008919	0.0116298	0.4772708	-0.5468214	-1.990169	27	ACP5 HMOX1 TMEM126A LAMP1 ID3 CEBPA DLEU2 TGFB1 CSDE1 SERPINE1 CDKN1B ITGB1	down	*
GO_3_5_CYCLIC_AMP_PHOSPHODIESTERASE_ACTIVITY	0.0015929	0.0180432	0.4550599	-0.7106799	-1.989727	12	PDE1B PDE4C PDE2A PDE4D PDE8A PDE3B PDE4B PDE4A PDE8B PDE7B	down	*
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_UP	0.0000003	0.0000135	0.6749629	-0.3829235	-1.989005	160	SC5D MCOLN1 SECISBP2L MIR22HG SIK1 OTUD1 INPP5A HEG1 IER2 DPEP2 CNST DNAJC3 BMP1 PTPRM UBL3 NAAA CLEC7A TIPARP EVI2B ITPRIP AHNAK PSTK KLF4 KLF11 C9orf72 DUSP1 RNF139 PLEK IL7R MYH11 MAFF VCPKMT SNN HCK MYLIP KLRB1 SGK1 SOCS3 JUN SNX29 MAP4K4 TYROBP ATXN1L SKIL KLF2 PTP4A1 TRAPPC10 FAM204A VAV3 GSAP ZRANB1 FAM228B TSC22D1 IRS2 PIM1 KCNA3 TOB1 RIMKLB MEGF6 KAT2B EPHA4 TTC28 EPB41L4A DNAJB9 ZFAND2A LYZ GREM1 TNFSF8 MDS2 NR4A2 FAM8A1 MUL1 DNAJB1 SPTY2D1	down	***
PID_ATR_PATHWAY	0.0001336	0.0024511	0.5188481	0.5648327	1.988691	38	TIMELESS PLK1 CDC6 MCM2 CDC25A ATR SSPO SMARCAL1 MCM7 CLSPN FANCD2 CDC25C TOPBP1 CHEK1 MDM2 RAD9A RPA1 CCNA2 RFC5 CEP164 RAD51 FBXW11	up	**
GO_TYPE_I_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_BINDING	0.0022364	0.0233127	0.4317077	-0.7590317	-1.988679	9	SMAD6 ENG TGFBR2 SMAD7 TGFB1 SMAD2 FKBP1A	down	*
GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP	0.0000003	0.0000118	0.6749629	0.4414198	1.988676	165	DDX11 KIF20A DEPTOR BUB1B CCDC34 POLQ DEPDC1 PIF1 TTK ANLN NUF2 CENPA ECT2 CCNB2 UHRF1 SLC35E3 XPNPEP1 CDC25A PRC1 ORC1 ZFYVE19 ZWINT SPDL1 WDR90 SDR16C5 MELK BUB1 AURKA EME1 IQCD MPHOSPH9 WDHD1 GPSM2 CDC25C TOPBP1 ORC6 HES6 SPC24 PSRC1 NCAPG2 NUSAP1 KCTD7 E2F1 NCAPG NEIL3 LRRC37A2 SAPCD2 FANCG CCNE1 CEP192 DCLRE1C TACC3 TK1 CHTF18 PCDH9 SASS6 PGBD5 CDC20 PEX5 RAB15 ATAD2 CYTH2 SLC2A5 ZMYND19 AGBL5 MXD3 CENPE SYNE2 SFXN4 E2F7 ZNF831 DDB2 ZNF367 ALPK1	up	***
MIR1269A_MIR1269B	0.0002000	0.0034434	0.5188481	0.5479084	1.988400	43	PCDHGA10 ZNF84 PCDHGA9 PCDHGA5 PCDHGA7 SLC25A21 PCDHGA1 PCDHGB3 PCDHGA11 PCDHGA8 PCDHGA12 RHOBTB3 PCDHGB7 PCDHGA3 BRIP1 URI1 PCDHGA2 UBFD1 ZNF160 ANKIB1 RER1 GLO1	up	**
GO_CELL_CELL_ADHESION_INVOLVED_IN_GASTRULATION	0.0022586	0.0234682	0.4317077	-0.7587263	-1.987879	9	MYADM IL1RN IL10 KLF4 MBP	down	*
SMID_BREAST_CANCER_BASAL_UP	0.0000000	0.0000000	0.9759947	0.4007077	1.987426	512	KIF1A IGHV4-61 DKK1 CEACAM1 TRIP13 PTPRZ1 CA9 BBOX1 FOXM1 HS3ST1 HELLS EPHB3 GALNT14 KRT5 LAD1 KCNK5 CDC45 MCM10 GMDS GABRP FAT2 S100A2 CP PROM1 NEK2 UGT8 CENPF UCHL1 IGF2BP3 MPP6 PBK KIF18B PKP1 DDIT4 MUC16 NDC80 PHGDH CHODL TUBB2B LCN2 TTK GTSE1 TSPYL5 SPP1 ASPM MMP1 KRT16 CDCA8 CENPA PTTG1 TBX19 CCL8 SOX9 TPX2 E2F3 CCNB2 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 FERMT1 COCH GLDC ORC1 DYNC1I1 PDE9A MOCOS CDT1 IGKV2D-28 KRT15 LDHB CXCL10 TTLL4 CLDN1 MELK IGLV3-10 EXO1 NUDT1 GPR37 CEP55 KCNN4 CHAF1A LAMC2 RPL39L MKI67 TRIM29 IGF2BP2 BUB1 FANCA IDO1 HOMER3 MYO10 VASH2 MCM7 MDFI TMEM45A RAD54L GPSM2 CHAF1B PFN2 RBP1 EGFR RIPK4 CDC42EP1 CHEK1 PDZK1IP1 SOX11 PFKP RAD51AP1 BACE2 PERP PML WNT5B SKP2 EDN2 NRTN CXCL11 NUSAP1 PLOD2 PPM1E CDK1 TNFRSF21 FAT1 UCK2 BIRC5 PLCH1 ITGB8 IGHG1 TNNI2 PRRX2 TRIM2 GJB3 PSAT1 PEG10 PDK1 CDH3 MRPS12 ARTN RAB6B RTP4 SRD5A1 HSPA4L LGR5 CRLF1 CCNE1 DLGAP5 SLC26A2 CHST3 CTSV FNDC4 TUBB2A IQCG SSRP1 DBN1 S100A9 ANP32E IFNAR2 STEAP1B MMP7 ASNS	up	***
GO_MITOTIC_SPINDLE_ASSEMBLY	0.0001794	0.0031297	0.5188481	0.5291568	1.987086	49	SPICE1 CHEK2 NEK2 RACGAP1 MSTO1 PLK1 AURKB TPX2 MYBL2 KIF23 KIF3B MAP10 TPR KIF11 CEP97 BIRC5 KIF2A KPNB1 CEP192 CDC20 AAAS CHMP4C CHMP1A CHMP2A GOLGA2 MAP9 CLASP1 DRG1 WRAP73	up	**
GO_CARDIAC_MUSCLE_CELL_MYOBLAST_DIFFERENTIATION	0.0023033	0.0238652	0.4317077	-0.7583607	-1.986921	9	TBX2 REST SRF RBPJ NOTCH1 MYOCD NRG1 GREM1	down	*
SRF_01	0.0007728	0.0104103	0.4772708	-0.4793567	-1.986890	43	EGR2 FOSL1 IER2 TNNC1 THBS1 KCNMB1 ACTR3 ACTG2 MYH11 MRVI1 JUNB CAP1 FOS FOSB TGFB1I1 WDR1 DIXDC1 CNN2 EGR1	down	*
GO_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE	0.0000472	0.0010314	0.5573322	0.5193447	1.986883	54	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB ESPL1 CDC6 CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 ANAPC5 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 CDC20 CDK5RAP2	up	**
GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0000003	0.0000110	0.6749629	-0.3742264	-1.986331	180	ZMYND15 OLR1 OSBPL11 SNX10 COQ2 YPEL5 PPM1D PILRA TMX4 PTS TACC1 LATS2 RASGRP4 ZNF410 LCP1 SERPINB9 C1orf162 TOR1AIP1 SIRPA SPI1 CD58 TAPT1 MAP2K3 CDADC1 ZSWIM6 NFKB1 P2RY2 KCTD20 TLR4 ARAP3 TM6SF1 DUSP1 DSE MYH11 KPNA3 CALM2 CNOT6L CDKN2AIP HCK CREM OASL HCST OSBPL9 TYROBP SKIL FRYL TMEM167B CDK17 AZIN1 VAV3 SERPINB1 NAB1 IFNAR1 STK40 XKR8 TAB2 SP100 PSME4 GNMT GIMAP4 SMAD4 DNAJA2 JDP2 CHIC2 CLIP1 SLC19A2 MAPK1 FHOD1 FAM8A1 UBE2W DR1 ATP2B4 MAP3K1 WDR26	down	***
GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK	0.0013228	0.0158018	0.4550599	-0.5719767	-1.986322	23	SIK1 CRY2 RBM4 PER3 USP2 FBXL3 PER2 ID2 PER1 GNAQ	down	*
GO_ATPASE_ACTIVITY	0.0000000	0.0000000	0.8753251	0.4096399	1.986073	366	KIF1A KIF12 ABCA13 DDX11 ABCC2 HELLS KIF20A DDX12P RUVBL1 CDC45 DNAH2 POLQ KIF18B TTF2 PIF1 GINS1 KIF14 ABCA12 PMS2P5 FIGNL1 MCM4 MCM2 RAD54B DNAH3 PMS2 XRCC2 DYNC1I1 MCM8 GINS4 KIF27 DNAH14 DNAI1 RUVBL2 TNNT2 KIF23 HLTF KIF15 KIF3B TOP2A MYO10 SMARCAL1 KIF2C MCM7 WDR78 ABCC5 RHOBTB3 HELB RAD54L KIF11 MCM3 PEX6 PFN2 WDR60 CHD6 DNAH8 MORC2 ABCB6 KIF3C ABCB9 DSCC1 DNAH11 BRIP1 BLM ERCC2 MNAT1 RECQL5 DDX56 NSF DDX51 DNAH6 KIF5A NAV2 DHX37 ABCC11 KIF19 DNA2 KIF2A DHX33 KIF7 DYNLL2 DNAH5 ABCA4 PSMC4 RECQL4 DHX34 MYO19 MOV10 DNAH7 DHX40 LONP1 KIF22 RAD51D CHTF18 KIF21A GINS2 KIF20B CHD5 ATAD5 ATP13A1 RAD50 ABCC10 EP400 ABCC9 WDR34 ABCC3 ABCA7 FANCM MCM6 CHTF8 WRNIP1 KIF21B DHX8 MCM5 DNAI2 ZRANB3 DDX23 DYNC2H1 KATNB1 IGHMBP2 MYH3 ABCD4 DDX55 ATAD2 PMS2P1 MSH4 PMS1 MSH2 SMARCA4 DDX54 ABCF3 RTEL1 RFC5 ABCF2 DNAH1 RAD51 SNRNP200 CHD3 RNF213 CENPE SRCAP DDX52 HSPA7	up	***
REACTOME_CELL_CYCLE	0.0000000	0.0000000	1.0175448	0.3981861	1.986014	547	FOXM1 CEP72 KIF20A HJURP RUVBL1 CDC45 MCM10 CHEK2 BUB1B NUP107 NEK2 CCNB1 CENPF MND1 NDC80 PRIM2 PIF1 BRCA1 TUBB2B GINS1 CDK4 GTSE1 POLE CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 E2F3 TFDP2 CCNB2 RBBP8 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 ORC1 DYNC1I1 MCM8 MIS18A GINS4 NCAPD2 ZWINT CDT1 DCTN2 SPDL1 HAUS5 CEP250 RUVBL2 HMMR BTRC EXO1 KIF23 STAG3 TP53BP1 KNTC1 RHNO1 BUB1 TOP2A CENPL AURKA NUP155 REC8 ODF2 POLA2 SYCP2 ATR POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 E2F2 CENPW CLSPN RRM2 LPIN3 CDCA5 MCM3 LMNB1 CDC25C LIG1 TOPBP1 CHEK1 ORC6 MAD2L1 PSMD4 CENPO MDM2 SPC24 AKT2 DSCC1 PKMYT1 BRIP1 BLM MNAT1 SKP2 INCENP CKS1B NCAPG2 CDKN2C ANAPC5 CDK1 POLE2 CENPJ DIDO1 CENPH BIRC5 GMNN SUN1 E2F1 NCAPG PSMB5 DNA2 KIF2A ANAPC7 FEN1 NUP205 DYNLL2 PSMC4 CENPP FGFR1OP KPNB1 RANGAP1 MZT2A MZT2B CEP63 CCNE1 CEP192 CDC23 TUBG1 PSMA5 NINL RAD9A TUBB2A PSME2 TUBA3D TK1 TUBA8 CHTF18 CENPQ HDAC1 ESCO2 GINS2 FZR1 LIN37 ANAPC1 POLD1 PSMD2 NUP85 PPME1 CDC7 RAD50 CENPK CKAP5 PSMB3 CDC20 CENPM TUBG2 AAAS RPA1 CHMP4C CDK5RAP2 UBE2V2 MCM6 CHTF8 DYNC1LI2 CENPT MCM5 UIMC1 HAUS6 GINS3 RCC1 HAUS4 PSMB4 CEP152 NUP62 MSH4 ALMS1 CCNA2 PRIM1 BANF1 RTEL1 ANAPC2 RFC5 TUBGCP4 CEP164 LPIN1 TUBA4B RAD51 ZWILCH SEC13 FBXW11 NME7 CHMP2A SMC2 MAU2 CENPE TP53 GOLGA2 LEMD2 SYNE2 CDC25B UBE2C NCAPD3 TUBA1C PPP2R5D NUP210 RAD1 PIAS4 CLASP1 NUP93 FBXL18 NCAPH CEP290 CHMP6 DYNC1H1 MLH3 TOP3A PLK4 AKAP9 PCNT DSN1 CDK11B RBL1 PPP2R5E FBXO5 PSMB10 LCMT1 TUBGCP2 PSME1 ATRIP NSL1 TMPO NHP2 NPM1 RNF8 RCC2	up	***
GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION	0.0000329	0.0007625	0.5573322	0.4921103	1.985838	70	TRIP13 DDX11 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDC6 CDT1 SPDL1 BUB1 TPR MAD1L1 CDCA5 MAD2L1 ANAPC5 FEN1 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 CDC20 CDK5RAP2	up	***
GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP	0.0000001	0.0000041	0.7049757	-0.3738211	-1.985704	179	SMAD6 CXCL3 IL1A CPEB2 IL1B F2RL3 EGR2 GTF2E2 IL1RN MOB1B IER2 SPG21 TRA2B BTG2 EIF5 PPP3CA NR4A1 NFE2L2 NDEL1 SRGN BTG3 ATP6V1H PDGFA RHOB IL10 RAB12 LIN7C PLAUR CDKN1A CXCL2 DUSP1 ZNF706 COPS4 CPLX1 ETF1 SGK1 SOCS3 C2CD2 STAT4 KCTD12 JUNB DNAJA1 PPP1R15A DHX15 IFRD1 EEA1 CD83 DDX5 ATP13A3 FOS PELI1 EHD1 TGIF1 PIM1 STK40 ETS2 IST1 ARPP19 ICAM1 HSP90AA1 RBM18 HNRNPK NFKBIA TNFSF9 EGR1 SERPINE1 CLEC4E NUP88 PIAS2 KCMF1 TES DLD IRF1 CUL2 MEF2D	down	***
SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN	0.0001469	0.0026538	0.5188481	0.6575035	1.985694	22	CCNB1 GTSE1 TPX2 CCNF KIF23 AURKA MCM7 CDC25C KIF22 DTYMK CDC20 MCM6 CCNA2 CDC25B UBE2C	up	**
GO_BLOOD_VESSEL_MORPHOGENESIS	0.0000000	0.0000000	1.0073180	-0.3352631	-1.985660	505	ANGPT4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB CDH5 ENG FOLR1 ECSCR SOX17 CAV1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 HSPG2 HEG1 RHOA APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM RAP1A ITGA5 CLEC14A HSPB1 FZD4 ANPEP NR4A1 JAM3 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 SPI1 PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 ROCK2 AMOTL1 NRARP TBX4 TNFSF12 TSPAN12 KLF4 ROCK1 THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HPSE MIR24-2 RECK PIK3C2A ELK3 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS HES1 PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ FLT1 IL6 WASF2 PKNOX1 CD160 NDNF JUN NOTCH1 ETS1 JUNB JAK1 RHOJ	down	***
GSE29618_BCELL_VS_PDC_UP	0.0000001	0.0000047	0.7049757	-0.3770453	-1.985333	170	SWAP70 CD55 LY86 PLEKHF2 BACH1 BCL2A1 CD22 IER2 TXNIP DPEP2 ATP2B1 MS4A1 CD37 RHOB PTPN12 EIF1B SYNPO FOXO1 YBX3 KLF7 CLIC4 LAPTM5 PTPRC DUSP1 HES1 IL24 ARHGDIB BTG1 PKIG ELF1 PHTF2 RAB8B PIKFYVE CD48 JUN SH3BP5 JUNB SNX2 CD83 TRAK2 IGKV3-20 CDK14 PLCG2 PELI1 KLF2 PTP4A1 CR1 GSAP PDLIM1 IRS2 KCNA3 MACF1 BMP2K CCR6 IER5 CDC42EP3 SP100 SCPEP1 ICAM3 CD19 NFKBIA LYST MMD AIM2 BANK1 PMAIP1 EGR1 CDKN1B NR4A2 PLEKHA2 TUBA1A CD69 CD79B PAX5 MTSS1	down	***
GO_NEGATIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE	0.0001598	0.0028393	0.5188481	0.5718124	1.984595	36	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 MAD2L2 KLHL22	up	**
GO_MRNA_TRANSCRIPTION	0.0010858	0.0135511	0.4550599	-0.5806297	-1.984561	21	EREG SOX18 LMO2 SOX17 C5AR1 HIPK3 SRF DDX5 ZBTB1	down	*
MORI_MATURE_B_LYMPHOCYTE_UP	0.0000274	0.0006503	0.5756103	-0.4260302	-1.984524	78	GPR65 TMOD3 SAMHD1 GGA2 MAP3K8 MS4A1 LCP1 ADRB2 MCL1 ID3 PTPRC SELL RAP1GDS1 HLA-DQA1 FAM76B ADD1 CMTM6 CNOT6L PHTF2 CTSS ETS1 IFNGR1 CD83 IRF8 RAB8A PXK MORF4L1 CD74 PEA15 MACF1 IGKV1D-39 PIP4K2A	down	***
MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP	0.0000047	0.0001474	0.6105269	0.4685469	1.984242	100	MDM1 CPLX2 CEP89 ELOVL6 BUB1B IGF2BP3 KIF18B PRIM2 UHRF1 AGK RANBP1 CISD1 MCM7 MMS22L WDHD1 LIG1 TOPBP1 AHCY CENPO DYRK2 CDK1 SPAG5 POC1B SAPCD2 TRAF5 CBX1 EFTUD2 UBE3D SSRP1 JMJD4 GINS2 GEMIN5 RAI1 ZNF428 HMGA1 FANCM U2AF2 STRBP SMARCA4 INO80E TYSND1 LLGL1 TCF3 TRIB2 SMPD4 MTHFD1 SEPHS1 SMARCB1	up	***
GO_NEGATIVE_REGULATION_OF_NUCLEAR_DIVISION	0.0000480	0.0010451	0.5573322	0.5186447	1.984205	54	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 CDT1 SPDL1 FBXO43 BUB1 TPR MAD1L1 TOM1L1 HORMAD1 CHEK1 MAD2L1 MTBP MAD2L2 KLHL22	up	**
GO_FATTY_ACID_BINDING	0.0010966	0.0136666	0.4550599	-0.5563937	-1.984116	25	FFAR4 PPARG FABP4 ACOXL APOC1 FABP5 SCP2 ID3 STX3 ALOX5AP	down	*
MIR711	0.0003085	0.0050054	0.4984931	-0.5096927	-1.983643	36	GATA2 WNT4 MYD88 TBXA2R SLC36A4 BNIPL CREBRF SYNPO2 NECAP1 C2CD2 TMEM230 DUSP5 C16orf72 MEX3C PAK2 SKI	down	**
GO_MOTOR_ACTIVITY	0.0000011	0.0000417	0.6435518	0.4585436	1.983075	120	KIF1A KIF12 KLC3 KIF20A DNAH2 MYO3B KIF18B MYH16 KIF14 DNAH3 DYNC1I1 KIF27 MYL6B DNAH14 DCTN2 DNAI1 KIF23 KIF15 KIF3B MYO10 KIF2C WDR78 KIF11 WDR60 DNAH8 KIF3C DNAH11 MYO1A DNAH6 KIF5A KIF19 KIF2A KIF7 DYNLL2 MYO5B DNAH5 MYO19 DNAH7 KIF22 KIF21A KIF20B KLC2 KLC4 WDR34 MYO5C DYNC1LI2 KIF21B DNAI2 DYNC2H1 MYH7B MYH3 MYH13	up	***
SRF_C	0.0000001	0.0000045	0.7049757	-0.3717745	-1.982892	183	MIR22HG EGR2 FOSL1 ANAPC15 IER2 ZEB2 JPH2 KCNK3 EMILIN2 FOXP1 KLF6 LCP1 NR4A1 CRK CNN1 UNC45B ROCK2 TNNC1 TRIM46 AOC3 THBS1 MYO1B KCNMB1 ACTR3 DSTN ACTG2 MYH11 MRVI1 SRF TRIM55 MITF JUNB RHOJ LYRM1 HERC1 OSM CAP1 YWHAZ RASSF2 GFPT2 MCAM FOS LMCD1 KRTCAP2 FOSB DUSP5 TGFB1I1 C16orf72 MEIS1 MRGPRF LTBP1 TAGLN MBNL1 PDLIM5 DIXDC1 PTCH1 ACTB G3BP2 CNN2 RSU1 STARD13 KALRN EGR1 CDC14A CFL2 DUSP6 DCUN1D3 YRDC DNAJB4 LDB3 PLN AKAP12 MATR3 SETD2 DACT3 DUSP2 NKX2-1 MYL9 FBXL22 MYLK SLC2A4 SPAG7 ANXA6 TANK	down	***
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_UP	0.0000006	0.0000237	0.6594444	-0.3872819	-1.982889	146	SLC31A2 DENND5A PTPRE SIK1 CD44 CTSW CITED2 AGTPBP1 TRIB1 CD8A HBEGF CD33 CSGALNACT2 KLF10 KLF6 RGCC SPRY2 TCF7L2 CFD ITM2B ZFAND5 STK17B MAP1LC3B RBMS1 PDE3B ID2 ZBTB43 PRF1 PER1 DUSP1 EVI2A ARL4A N4BP2L1 BTG1 MYLIP HCAR3 JUN PSMA1 GLIPR1 GPR183 IGKV3-20 FOS KLF2 AZI2 FOSB MARC2 IRS2 RGS2 HELZ SF1 CEBPD SIK3 NFKBIA WDFY3 DMXL2 NR4A2 TGOLN2 ANKS1A ZFP36 ATP1B1	down	***
GO_BICARBONATE_TRANSPORT	0.0001292	0.0023900	0.5188481	0.5762952	1.982721	34	CA9 SLC26A4 HBA1 HBA2 SLC26A8 SLC4A3 SLC4A4 CA12 HBB SLC4A8 SLC4A11 SLC26A2 SLC4A2 SLC4A9 SLC26A1	up	**
GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP	0.0000002	0.0000100	0.6901325	0.4363986	1.981609	177	CEACAM1 TRIP13 HJURP BDH1 ELOVL6 NEK2 POLQ BRCA1 TTK TRAIP GMPS PLK1 MYBL2 CCT6A NCAPD2 CDT1 RUVBL2 EXO1 MKI67 EMC9 KNTC1 PUS7 FSD1 B3GNTL1 DNAJC9 CAD PHB PON2 FAHD2A UCK2 POLR3K NEIL3 CCDC88C EZH2 LRRC42 RNASEH2A ILF2 OSBPL3 MRPL11 SSRP1 CENPQ ASNS MAGOHB CCT7 RAD50 GEMIN6 SUPT16H PFAS TIMM13 MRPL28 PPCDC HEATR1 TDP1 LANCL2 DUS4L PSMB4 TCERG1 SUV39H2 PRIM1 RAD51 GRAMD1B SEPHS1 PAICS SNRPC NCAPD3 RAD1 PPP1R14B BRIX1 CYB5B AVEN MRPS16 DGUOK C12orf43 RWDD2B AP2B1 TIMM10	up	***
MORI_PRE_BI_LYMPHOCYTE_UP	0.0000692	0.0014135	0.5384341	0.4936599	1.980435	68	HJURP NDC80 PHGDH CDCA7 TTK RACGAP1 E2F8 CCNB2 MCM2 PRC1 GRB7 DTL MELK SMARCC1 MKI67 TOP2A AURKA MCM7 RRM2 CDCA5 LMNB1 LIG1 HSPBP1 CKS1B CDK1 PSAT1	up	**
IIZUKA_LIVER_CANCER_EARLY_RECURRENCE	0.0016870	0.0187696	0.4550599	-0.7447588	-1.979992	10	LAPTM5 VIM CCND2 SGK1 DDX17 REL	down	*
NEMETH_INFLAMMATORY_RESPONSE_LPS_UP	0.0000531	0.0011362	0.5573322	-0.4357963	-1.977963	69	SLPI MNDA CD44 MYADM CITED2 HMGCR IL1RL1 IL1RN SLC11A1 IER2 EIF1 SRGN MSR1 PIP5K1B DAB2 CCL3 NFKB1 CDKN1A ATF3 KPNA3 DEGS1 HCK ETF1 IFRD1 CLN3 BCL6B TGFB1 ETS2 CEBPD NFKBIA TNFSF9	down	**
GSE22886_NAIVE_BCELL_VS_DC_DN	0.0000001	0.0000052	0.7049757	-0.3718654	-1.977793	184	EPAS1 SLC31A2 HMOX1 RAPGEF2 TRPV2 CCDC88A RTN3 CITED2 FLVCR2 MKNK1 EPB41L3 PILRA CD36 PLA2G7 MAN2B1 CLEC7A IFI30 KLF10 GLS SLC7A11 ABHD6 SIRPA ZMYM6 TFEC SRGN CD58 ZMIZ1 MTMR6 GAA SLC7A8 CEBPA PLBD1 RIT1 TM6SF1 PLEKHB2 FCER1G PINK1 DSE TM9SF2 IL7R VAMP3 PGD SLCO2B1 PPA2 MITF RHOG SDHD SNX1 TNFSF13 PEA15 ATXN1 NQO2 GABARAPL1 FCGRT ZNF267 GPX3 VASH1 ARRB2 RTN4 TIAM1 LRP12 SOAT1 GLRX2 SNAP29 SAMSN1 DOCK4 HEBP1 EHD4 FEZ2 ZFYVE26	down	***
GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN	0.0000003	0.0000145	0.6749629	0.4356978	1.977012	176	GMDS NEK2 CCDC34 MPP6 PBK PIF1 TTK E2F8 ANLN CDCA8 AURKB DIO2 MCM4 TYMS CA12 PRC1 GLDC NCAPD2 SPDL1 NME1 RANBP1 MELK HMMR MRPL15 KNTC1 EME1 CDCA5 RAD54L CHEK1 ASS1 C7orf50 ACTL6A MAD2L1 RAD51AP1 DCTPP1 GNPDA1 FLNB PTPN3 INCENP RNF216 CKS1B CXCL14 RFWD3 CENPH C1orf112 SDCBP2 NEIL3 SPAG5 ETFB CCNE1 TACC3 OSBPL3 KIF22 TRIM37 TK1 DTYMK CASP7 GINS2 SAP30 MAGOHB HLA-A CDC20 ASRGL1 CKAP2 MCM5	up	***
GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_UP	0.0000001	0.0000062	0.6901325	-0.3723810	-1.976914	174	EREG TMEM52B RDX RTN3 QKI BMPR2 LAMP1 TGFBR2 FAM49A HBEGF RAP1A SERINC1 CNTD1 SLAIN2 NDEL1 GRN AKT3 ZEB1 FBXL5 ZMIZ1 ACSL3 KLF9 GAPVD1 UBQLN1 UBE2B RNF139 MFSD11 HTT PIK3R5 IL24 ANXA3 AKIRIN1 FAM102B NCKAP1L RAB8B VPS26A DHX15 FBXO11 SKIL ENPP4 CD83 MBNL2 ATL2 SLC10A7 HSF5 BTBD7 STXBP3 TAGAP MFSD12 KAT2B CCR6 EXOC2 ZNF583 TRAPPC8 PTCH1 ULK2 PAK2 ST6GAL2 LYST AIM2 IQGAP1	down	***
GO_B_CELL_PROLIFERATION	0.0000738	0.0014981	0.5384341	-0.4387204	-1.976840	68	GAPT MNDA CD22 CLCF1 ADA MS4A1 IFNK WNT3A TFRC IL10 BST1 CDKN1A PTPRC TLR4 IL7R NCKAP1L TYROBP GPR183 RC3H1 PELI1 CD74 VAV3 IRS2 CD81	down	**
GO_NEUTROPHIL_HOMEOSTASIS	0.0015069	0.0173146	0.4550599	-0.6389415	-1.976812	16	HCAR2 ANXA1 SH2B3 SLC7A11 JAM3 MPL AXL IL6	down	*
WORSCHECH_TUMOR_REJECTION_UP	0.0003945	0.0061084	0.4984931	-0.4740785	-1.976387	44	CXCL3 IL17RB IL1A IL1B MNDA CCRL2 CLEC10A BCL2A1 MSR1 CCL22 CXCL2 TLR4 KLRD1 IL7R	down	**
GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_DN	0.0000001	0.0000062	0.6901325	-0.3722642	-1.976294	174	HMOX1 MS4A7 SGK3 PECAM1 PPARG FABP4 HSD17B11 SLC25A30 TGFBR3 BCL2A1 GIMAP6 PILRA TXNIP EDEM1 RAPGEF4 SERINC1 PICALM PAG1 SIRPA RGCC TFEC TFRC MCL1 CST3 EPB41L2 AGO4 EPOR SDCBP PTPRO MEFV KLF4 STK17B C9orf72 RNF139 CD300C RPL17 MYO1C FRY CTSZ CELF1 JAK1 CDK2AP2 NDST1 PLCG2 SLC3A2 KLF2 SRSF6 SPOP IRF5 SORT1 AKIRIN2 KANSL2 RGS2 CPQ METTL7A STK4 JMJD1C CD3G SNAP29 CYTH1 MT2A RSU1 SMAD4 ARHGEF18 UBAP1 HIPK1 FTL ZFP36 FAM53B RNF167	down	***
AMIT_SERUM_RESPONSE_120_MCF10A	0.0001024	0.0019731	0.5384341	-0.4409075	-1.975751	62	CD55 SOWAHC BMP2 SIK1 NEDD9 CLCF1 KLF10 MCL1 SETD3 KLF4 PLAUR ID3 ID2 MAFF RYBP BCAR3 JUNB FERMT2 SKIL PDZD2 FEM1B IRS2 PIM1 STX12 ETS2 PDLIM5 CDKN1C EDN1 SPHK1 YRDC IFIT5 DAPP1	down	**
STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN	0.0002935	0.0047997	0.4984931	0.5636474	1.975432	37	MCM10 SLC27A2 CDC6 MCM2 CDC25A DTL WDHD1 SKP2 NCAPG2 POLE2 FEN1 ULK1 GINS2 MCM6 RAI14 MCM5 GINS3 CHRNA5 ATAD2 CAP2 ZWILCH CELSR2	up	**
GO_SINGLE_STRANDED_DNA_HELICASE_ACTIVITY	0.0002145	0.0036381	0.5188481	0.7057903	1.975102	16	POLQ PIF1 MCM2 MCM7 HELB DSCC1 DNA2 CHTF18 MCM6 CHTF8 MCM5 RFC5 RAD51	up	**
BIOCARTA_INTEGRIN_PATHWAY	0.0008698	0.0114355	0.4772708	-0.5225963	-1.975021	32	FYN CAV1 RHOA RAP1A TNS1 ROCK1 JUN RAPGEF1 GRB2 MAPK8 ACTN2 MAPK1 ITGB1 ZYX	down	*
GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN	0.0000004	0.0000176	0.6749629	0.4383544	1.974866	165	FOXM1 KIF20A CEP89 CDC45 PARPBP NUP107 PRIM2 PIF1 TTK GTSE1 POLE STIL MSTO1 CDCA8 ECT2 UHRF1 MCM4 PMS2 MIS18A NCAPD2 MELK NUDT1 CEP55 TSGA10 CENPL NUP155 MPHOSPH9 WDHD1 FANCD2 CDC25C TOPBP1 CHEK1 AHCY CENPO RAD51AP1 SLC25A39 SPC24 FBXL8 CBX5 RFWD3 GMNN NEIL3 EZH2 DDT CENPP ULK1 PIAS3 DHX40 LMNB2 KIF22 GINS2 ANP32E KIF20B LRWD1 CEP128 ATAD5 CENPT CD2BP2 LANCL2 LSM4 ERGIC3 STK35 WDYHV1 ATAD2 STK38 ARHGAP11A CENPE PAICS SIAE TTC9C RIPK3 PPP2R5D C4orf46 NCAPH C9orf40 CNPY4	up	***
MODULE_492	0.0011255	0.0139181	0.4550599	-0.6777587	-1.974329	13	FUCA1 ASAH1 ATP6V1B2 GLB1 HEXB	down	*
chr4q22	0.0010553	0.0132480	0.4550599	-0.5423594	-1.973929	27	HSD17B11 MMRN1 KLHL8 NUDT9 ABCG2 HERC3 PPM1K TMSB4XP8 HSD17B13 HPGDS GPRIN3 PKD2 NAP1L5 PDLIM5 SPARCL1	down	*
GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP	0.0000002	0.0000090	0.6901325	-0.3752752	-1.973863	164	ABHD5 SPN SNX10 PTPRE CD44 MYADM FAM49A IER2 ZEB2 ANXA1 ENTPD1 ZDHHC2 SERPINB9 LAIR1 NR4A1 IL18R1 MPHOSPH6 SRGN BAG1 AHNAK CASP1 YBX3 COQ10B MAP1LC3B ITGAX ID2 CCL4 PRF1 PLEK DSTN INSL6 CALM2 MTPN CD48 CCDC50 IFNGR1 GMFG COBLL1 TBX21 NKG7 KLRC2 PIK3AP1 GIMAP1 SMPDL3B CHPT1 GSAP DUSP5 ATP6V0C NQO2 PHF11 GEM IL18RAP YAF2 CDC42EP3 ARHGAP18 ING2 TNFSF9 RORA PMAIP1 CX3CR1 ITGAL ITGB1 ZYX S100A8 NDFIP1 MICAL1 SPTY2D1 S1PR5 GPR55 CRIPT ATP2B4 NFIL3 RPA2 ATF6 DOCK5 TTC39B MYO1F KLRC1 F2RL2 SLAMF7 LEPROT	down	***
SANSOM_APC_TARGETS_REQUIRE_MYC	0.0000001	0.0000029	0.7195128	0.4275960	1.973724	198	BUB1B TIMELESS PHGDH METTL1 CDK4 GTSE1 POLE KNOP1 SHMT2 NME1 WDR62 SMARCC1 QTRT1 SLC29A2 GTPBP3 MCM7 RAD54L MCM3 SOX4 SMYD5 SIDT1 FBL GAS8 HES6 CAD FADS2 THOP1 WDR54 GNPNAT1 SAPCD2 CENPP RNASEH2A ANKRD39 GIPC1 DENND6B TELO2 POFUT1 NFS1 ADAT1 LMNB2 TRIM9 TUBB2A HIRA EPHB2 DPH2 TK1 DTYMK MYBBP1A STOML1 ATG9B GINS2 GEMIN5 SRD5A3 ZSWIM3 NRF1 SLC1A3 CCT7 WDR34 AAAS RRP9 RAI14 LANCL2 PTHLH MYEF2 LHPP DDAH1 NTMT1 HAGHL CDC42BPA TMEM141 RNF157 WDR4 FARSB RASSF4 ZMYND19 POLR1A SMPD4 TP53 SIGMAR1 PTOV1 NELFA PPP1R14B ASCL2 RANGRF ROR2 ALKBH2 USP20 MED22 MUS81 NSUN5 SRM ATRIP TMPO NHP2 DUS3L RCC2 D2HGDH SHMT1 PCBP4 LRP8 ZNF790 CCDC86 TP53RK LFNG DDX49	up	***
GO_PHAGOCYTIC_VESICLE_MEMBRANE	0.0001559	0.0027829	0.5188481	-0.4502292	-1.973714	57	RAB11FIP1 MCOLN1 HVCN1 LAMP1 SLC11A1 RILP ATP6V0D2 ANXA3 VAMP3 INPP5B SNAP23 RAB8B RAB31 RAC2 ATP6V0B RAPGEF1 RAB8A ATP6V0D1 PIK3C3 ATP6V0C RAB5A CYBA ATP6V0A1	down	**
GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN	0.0000004	0.0000171	0.6749629	0.4415652	1.973143	154	SLC16A14 CEP89 FBXW8 HOXD8 NEK2 APOLD1 SRGAP3 RACGAP1 E2F8 POLE STIL EFNA4 ESPL1 BCL2L14 SHMT2 FSTL4 CLSTN3 KNTC1 TOP2A EME1 NDUFS2 IFT43 CDCA5 SLC4A11 KIF11 KDELR2 MAD2L1 SPC24 PML FADS2 PPIL1 TXLNB NCAPG2 TMEM106C ASF1B CLMN C1orf112 NUDT2 SSX2IP CXCL17 HYKK DNMT1 CCNE1 KIF22 MLEC GINS2 ETV4 CDC20 HPD MGME1 ADAMTS12 CENPT CACNB3 GGT5 UNC119B LHX4 PRIM1 ACSF3 ARHGAP11A SUPT3H TONSL GMPR2 LOXL4 FAM78B MRPL20 KIF24 CASKIN1 PCGF2 HRAS GSTT2 KHDRBS2 LTK TOMM40 STARD10 PMVK	up	***
SMID_BREAST_CANCER_NORMAL_LIKE_UP	0.0000000	0.0000000	0.9214260	-0.3384562	-1.972050	414	MGAT3 ACVRL1 CD52 SOSTDC1 PECAM1 HHEX FABP4 CLEC3B TIE1 LYVE1 THBD LYL1 FYN LPL EMCN CTSW CCDC88A FCER1A KANK3 CAV1 CRY2 CLEC10A ELMO1 TGFBR3 GIMAP6 CD1C CD22 FAM49A LILRB3 ABCB1 CD8A PDE2A TXNIP RNF125 MALL MS4A1 DES IL18R1 SFRP1 SPRY2 CES1 ZEB1 SRGN CD37 CNN1 PPP3CC FLI1 ADARB1 EVI2B TLE4 SORBS1 CASP1 AOC3 ST3GAL2 CPVL RUNX1T1 SLC12A4 FMO2 ID3 CLDN5 LY96 ITIH5 LAMC3 COTL1 RBMS1 PTPRC CXCL2 SELL CD302 PRF1 MATN2 MATK VAMP5 IL7R MYH11 MAPRE2 FOXN3 NCKAP1L TRGC2 FAM107A ID4 TMOD1 IL6 KLRB1 CD48 KCTD12 RAC2 PTGER4 CCR7 GLIPR1 PIK3R1 IRF8 GMFG GPR183 NPR1 MFAP4 SNX1 CD7 LGALS2 PALMD CELF2 IGKV3-20 RRN3 SIGLEC1 GJA4 HIVEP2 MBP RUNX3 ICAM2 NKG7 CD74 BIN2 MME TCF4 CD1D CD6 VPREB3 DOK2 GPR18 CLEC2B CCR6 GEM TRAC LAT TNFAIP8 CCDC69 SPARCL1 TFPI LMOD1 SPIB CDKN1C EPHA4 GIMAP5 NLRP3 ACACB MT1M CD19 KIT CTSC CD1E DOCK10 CD3G KLRK1 ABCA8 GPR171 THEMIS2 NR3C2 GIMAP4	down	***
GO_TUMOR_NECROSIS_FACTOR_BIOSYNTHETIC_PROCESS	0.0026740	0.0266081	0.4317077	-0.5589727	-1.971506	24	SPN TNFRSF8 CLEC7A HSPB1 IL10 THBS1 TLR4 PSEN1 TYROBP	down	*
LY_AGING_PREMATURE_DN	0.0001071	0.0020529	0.5384341	0.6218886	1.971396	26	FOXM1 CENPA MCM2 TYMS MYBL2 CCNF RANBP1 KIF2C FBL PKMYT1 PARP1 CKS1B CBX1 ENPP2	up	**
GO_VASCULOGENESIS	0.0000843	0.0016701	0.5384341	-0.4374596	-1.971159	68	TMEM100 FOXF1 SOX18 RASIP1 TIE1 EMP2 RAPGEF2 RAMP2 ENG SOX17 CAV1 QKI TGFBR3 TGFBR2 HEG1 RAP1A FZD4 TIPARP ZMIZ1	down	**
GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN	0.0000002	0.0000088	0.6901325	-0.3762530	-1.971098	163	CD55 INPP5K YPEL5 STX11 CCNL1 TOE1 CHMP1B BTG2 KLF10 NR4A1 CD37 TIPARP MAP2K3 CFD PRDM16 SRSF5 SAP30BP TPSG1 ZCCHC24 CPVL MAP1LC3B TLR4 DUSP1 RSL24D1 AKIRIN1 BTG1 S1PR4 ELF1 OASL SRSF3 MAP4K4 TREM1 PPP1R15A PTGER4 IFRD1 PABPC4 OSM SNRK KLF2 PTP4A1 USP7 ICAM2 FOSB CD74 RPL21 GABARAPL1 RNF2 JUND EIF3F CXCR4 SP100 SCPEP1 RPS13 ICAM3 DNAJA2 PMAIP1 AQP5 NR4A2 CRBN EIF3L	down	***
GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN	0.0000001	0.0000053	0.7049757	-0.3719456	-1.970557	173	SLPI ABHD5 GPR15 FABP4 SLC6A12 EGR2 CCRL2 AKAP7 SLC25A30 S1PR1 SLC15A3 P2RY13 MARCO NR3C1 FGR PLA2G7 SGMS2 GNGT2 TMEM204 EIF5 AHRR ZNF503 LITAF PAG1 SPRY2 SRGN BTG3 TUBB6 FBXL5 MSR1 FABP5 RAB12 BST1 PLBD1 NR1D2 CEP57 GCA INHBA MBD2 IL7R NUS1 PLEKHA3 SERPINB8 JUNB FAM43A OSM PTGER2 CD164 AZI2 CD74 UBXN2A CD1D TCP10L TGIF1 FPR2 CD86	down	***
GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN	0.0000001	0.0000033	0.7049757	-0.3704620	-1.969935	176	ZC3H12C GPR65 EGR2 GTF2E2 CITED2 FOSL1 CYB5R3 MKNK1 MARCO NEDD9 BCL2A1 IER2 PPP1R15B EIF1 MTF1 BTG2 MAP3K8 KLF6 NR4A1 NDEL1 CLK1 TIPARP RHOB IL10 SRSF5 BIRC2 RNFT1 ZFAND5 RMDN3 SNIP1 ATF3 CCL4 DUSP1 EVI2A SH2D2A BTG1 SLC25A25 AREG IL6 SGK1 SOCS3 KCTD12 PLK3 JUNB PPP1R15A FOS PELI1 JMJD6 TGIF1 IRS2 TPMT CCR1 KAT2B ETS2 GEM SERTAD1 CXCR4 TBCEL NFKBIA MAFK LYST DNAJB9 TLK2 TNFSF9 LDLR NABP1 SFPQ YTHDC1 EGR1 DUSP6 PRKCH SLC38A2 ZFP36 MT1E DNAJB1 TMEM11 BCL10 IRF1 NFIL3 TAF1D FASTKD5	down	***
KEGG_CELL_CYCLE	0.0000048	0.0001505	0.6105269	0.4565291	1.969335	118	CDC45 CHEK2 BUB1B CCNB1 TTK CDK4 PLK1 PTTG1 ESPL1 CDC6 E2F3 TFDP2 CCNB2 MCM4 MCM2 CDC25A ORC1 BUB1 ATR MCM7 MAD1L1 E2F2 PRKDC MCM3 CDC25C CHEK1 ORC6 MAD2L1 MDM2 PKMYT1 SKP2 CDKN2C ANAPC5 CDK1 E2F1 ANAPC7 MAD2L2 CCNE1 CDC23 HDAC1 FZR1 ANAPC1 CDC7 CDC20 MCM6 MCM5	up	***
HORIUCHI_WTAP_TARGETS_DN	0.0000000	0.0000001	0.8012156	0.4148133	1.969109	280	HMGA2 DKK1 TRIP13 DDX11 FOXM1 HELLS KIF20A HJURP TROAP BUB1B NEK2 CCNB1 PBK KIF18B NDC80 DEPDC1 TTK CDCA2 RACGAP1 GTSE1 KIF14 ANLN ASPM MSTO1 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 TPX2 CCNB2 UHRF1 TYMS MYBL2 PRC1 NCAPD2 COQ3 LDHB MELK HMMR KIF23 CEP55 MKI67 BUB1 TOP2A DPY19L1 AURKA KIF2C MCM7 CENPW RRM2 FSD1 KIF11 FANCD2 LMNB1 ZNF618 MAD2L1 CKAP2L FBL RAD51AP1 TIMM50 SPC24 PHB RGS4 PSRC1 CKS1B NUSAP1 ASF1B CDK1 BIRC5 ULBP2 GMNN UNG NCAPG PEG10 SPAG5 NLN UQCC2 KPNB1 DLGAP5 SNRPA LMNB2 KIF22 TK1 ENAH SYT1 TWF1 POLD1 CCT7 SULT1B1 CDC20 TMEM106B CENPM HMGA1	up	***
GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN	0.0000002	0.0000100	0.6901325	-0.3712743	-1.969052	182	SIDT2 FAM167A FYN BACH1 S1PR1 ZBTB2 FAM49A ACER3 KIAA0355 SLC44A2 ATP2B1 RRAGC UBL3 MAP3K8 REV3L FOXJ3 BNIPL EPB41L2 ITPRIP DUSP3 REST TMED5 CLIC4 NR1D2 TEF M6PR ADIPOR2 DEGS1 AFF1 CNOT6L SRF BTG1 SLC25A25 RYBP RBM34 SH3BP5 CUL4A PLK3 EPC1 WTAP IFRD1 IRF8 MSANTD2 GTDC1 DENND4A CEBPZ ZBED5 MAPK8 CD74 DCAF5 SERPINB1 VPREB3 TEC TSC22D1 NAB1 STK40 NBEAL1 CDC16 RIPK2 BRWD1 SCPEP1 PLGRKT TBCEL MAFK DOCK10 C21orf91 GIMAP4 ZFAND2A DNAJB5	down	***
BIOCARTA_GRANULOCYTES_PATHWAY	0.0011850	0.0145074	0.4550599	-0.6759331	-1.969011	13	IL1A PECAM1 SELL SELP ICAM2 ICAM1 SELPLG C5 ITGAL CSF3	down	*
WHITFIELD_CELL_CYCLE_G2	0.0000004	0.0000175	0.6749629	0.4418132	1.967769	149	UNC5CL HJURP TFAP2A CHEK2 POLQ MND1 TTF2 NDC80 PIF1 CDCA2 ANLN TRAIP STIL CDCA8 AURKB ESPL1 CCNF RCCD1 WDR62 MELK KIF23 RHNO1 TOP2A CENPL TMEM132A KIF11 FANCD2 LMNB1 CDC25C MAD2L1 CKAP2L TRMT2A ZNF587 DET1 ENTPD5 PSRC1 CDKN2C CXCL14 NUSAP1 CBX5 CDK1 AP3D1 NEIL3 TNPO2 FADD RANGAP1 ARHGAP11B TUBB2A KIF22 FZR1 KIF20B SAP30 BRD8 VPS25 CDR2 CKAP2 DHX8	up	***
GO_SIALIC_ACID_BINDING	0.0021392	0.0226219	0.4317077	-0.7856866	-1.967484	8	SIGLEC11 FCN1 CD22 CD33 SELP	down	*
GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP	0.0000002	0.0000092	0.6901325	0.4358792	1.967384	167	MDM1 TROAP BUB1B IGF2BP3 KIF18B DEPDC1 DEPDC1B CDCA7 TTK IQGAP3 E2F8 GTSE1 ANLN PLK1 CDCA8 CENPA ESPL1 TPX2 FIGNL1 MCM2 ACY1 MAP2K6 NCAPD2 KIF23 MKI67 AURKA POLA2 SMARCAL1 KIF2C CDCA5 KIF11 SOX4 CKAP2L PIH1D1 PPP5C FADS2 INCENP ASF1B CDK1 POLE2 SUN1 E2F1 ANAPC7 SPAG5 VPS72 EIF6 DPP3 NMRAL1 SSRP1 TK1 CHTF18 HDAC1 EDARADD POLD1 RNF187 CKAP5 CDC20 MGME1 MED24 EIF3D IL12RB2 POLR2I LSM4	up	***
TIAN_TNF_SIGNALING_VIA_NFKB	0.0027269	0.0270196	0.4317077	-0.5576810	-1.966950	24	CXCL3 NFKB1 CXCL2 IL6 CD83 REL TNFRSF9 GFPT2 CCL20 TRAF1 NFKBIA ZFP36 IRF1 PTGS2 RELB TNFAIP2 TNFAIP3	down	*
SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX5_UP	0.0020128	0.0215362	0.4317077	-0.7393754	-1.965680	10	PID1 EMCN ACER3 SFRP1	down	*
GSE3982_DC_VS_TH1_UP	0.0000001	0.0000037	0.7049757	-0.3696032	-1.965368	176	SMAD6 SIDT2 CD52 TAL1 THBD SLC6A12 LYL1 FCER1A RASAL2 PCOLCE2 C5AR1 CLEC10A SLC15A3 IGSF6 PILRA FGR LRRFIP2 CD36 ANXA1 CYB5A ANPEP ABHD6 RGCC SPI1 CFD ARRB1 MVB12B DRAM1 TPP1 TMBIM1 PDE8A CLIP4 GNAQ RUFY3 LMBRD1 CLN8 TMEM9B FLT1 CTSS C1QA CUL4A GAS2L1 PDE5A ZNF804A CR1 PEA15 CD1D CTNNAL1 CSDE1 ADPGK KYNU RGS2 SESN1 IL18 CES3 PARM1 IFFO1 SCPEP1	down	***
CHEN_HOXA5_TARGETS_9HR_UP	0.0000000	0.0000011	0.7337620	-0.3630368	-1.965174	205	TBX3 THSD1 THAP9-AS1 BACH1 NEDD9 RCHY1 IER2 CCNL1 EIF5 KLF10 KLF6 HLX CLK1 MCL1 TIPARP BIRC2 ARNTL ATF3 CLK4 MAFF NRBF2 MARK3 AKIRIN1 RABGGTB RSRC2 CDKN2AIP VCPKMT ZNF426 RBM39 RYBP CREM JUN HRH1 JUNB DUSP8 RCAN1 IFRD1 MORC3 TNFRSF9 TNFRSF10B ZNF20 FOS PELI1 CDK17 FOXO3 FOSB ING3 ADPRM TSC22D1 ZCCHC10 CEP76 DUSP5 ZNF136 PPIG GABARAPL1 CRY1 ZNF267 ETS2 ATAD2B GEM INTS6 NEK1 RLF RIPK2 ARIH1 SRSF10 FNBP4 NFKBIA JMJD1C TLK2 ZNF165 C21orf91 C2orf42 FAM13B SFPQ SPATA5L1 PMAIP1 EGR1 DUSP6 CENPC CCNT2 PPWD1 WAC ZNF14 BCL10 TSC22D2 CDK7 PYROXD1 NFIL3 PNRC2 RNF111 TAF1D PTGS2 ZNF331 CASP3 SREK1	down	***
GO_ENDOTHELIUM_DEVELOPMENT	0.0000197	0.0004970	0.5756103	-0.3900935	-1.964240	112	TMEM100 ACVRL1 SOX18 PECAM1 IL1B RDX RAPGEF2 CDH5 ENG SOX17 MYADM BMPR2 S1PR1 HEG1 RHOA PDE2A RAP1A FOXP1 ZEB1 PDE4D FOXC2 RHOB ROCK2 ROCK1 TJP1 CLDN5 CLIC4 ITGAX ARHGEF26 ADD1 BTG1 RBPJ	down	***
GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000002	0.0000076	0.6901325	-0.3690593	-1.964188	177	ZMYND15 OLR1 MCOLN1 DENND5A INSIG1 QKI TBC1D7 SLC15A3 BCL2A1 HPS5 EDEM1 EIF4A1 B3GNT5 LATS2 KLF10 TFRC DIABLO ZMIZ1 DUSP3 SGTB PLAUR MAP1LC3B SPAG9 NR1D2 C9orf72 ADIPOR2 OXSR1 FKBP15 MAFF SEC31A SNN RBPJ GZF1 RAB8B ARL5B STAT4 SKIL CD83 ATP13A3 SUCNR1 CLN3 SLC3A2 HIVEP2 AZIN1 SAV1 ZBTB1 NAB1 SOD2 LGALS3 GABARAPL1 NBEAL1 RIMKLB MFSD12 PDE4B BNIP3L IER5 ZBTB25 TXNDC11	down	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP	0.0000006	0.0000222	0.6594444	-0.3758114	-1.964165	162	IL1A DENND5A USP12 AQP9 SFR1 BCL2A1 AGPAT4 FAM49A RFTN1 SLC7A7 MTF1 TNIP3 RNF144B PTX3 SLC25A37 AKT3 CASP5 IL10 TBC1D9 TNFSF15 DENND3 SOCS2 CLIC4 NFKB1 P2RY2 CXCL2 ZBTB43 HES1 TP53BP2 IL24 PROCR KANK1 HCAR3 FLT1 IL6 SOCS3 STAT4 SH3BP5 HRH1 WTAP ELOVL7 ENPP4 HSPA13 OSM FSD1L TNFRSF9 ACSL1 AZIN1 SAV1 EHD1 SERPINB1 FPR2 PIM1 ETS2 CCL20 MIR155HG IER5 CDC42EP3 PLGRKT MAP3K4 BCAT1 NFKBIA MAGI2-AS3 MCOLN2 TRIM36 RABGEF1 SLC16A10 SVIL DCUN1D3 OSGIN2 MSANTD3 YRDC HEY1	down	***
LINDGREN_BLADDER_CANCER_CLUSTER_3_UP	0.0000000	0.0000001	0.7881868	0.4145295	1.964004	274	RHPN2 TRIP13 CDC45 SLFN13 NEK2 CCNB1 CENPF GGCT DEPDC1 TTC39A BRCA1 RACGAP1 E2F8 KIF14 TRAIP PLK1 CDCA8 CENPA PTTG1 CDC6 CCNB2 FIGNL1 MCM4 TYMS CDC25A MYBL2 PRC1 ORC1 COPB2 MCM8 LIG3 MIS18A XPOT ZWINT CDT1 AOC1 CLPTM1L MELK EXO1 KIF23 CEP55 CHAF1A HLTF BUB1 TOP2A AURKA SAE1 KIF2C POC1A CPD RRM2 WDHD1 RAD54L TOM1L1 KIF11 CHAF1B RNFT2 LIG1 ASS1 MAD2L1 RAD18 IDH2 ZNF587 CKS1B NCAPG2 CDKN2C C12orf75 CXCL14 TMEM106C URI1 CDK1 SNX4 UCK2 BIRC5 GMNN E2F1 REEP6 EZH2 MRPS12 RAB11FIP4 PSMC4 MAD2L2 LINC00173 RNASEH2A CCNE1 GNPAT DLGAP5 WDR53 TACC3 MNS1 MORN2 TK1 CENPQ GINS2 CDC7 WDR34 FAF1 FAM136A BCL2L1 MCM6 CKAP2 MCM5 C5orf22 ATAD2 ZNF286A DDAH1 PYCR1 CEP85 GLO1 MSH2	up	***
REACTOME_G2_M_CHECKPOINTS	0.0000021	0.0000726	0.6272567	0.4532974	1.963256	121	CDC45 MCM10 CHEK2 CCNB1 BRCA1 GTSE1 CDC6 CCNB2 RBBP8 MCM4 MCM2 CDC25A ORC1 MCM8 EXO1 TP53BP1 RHNO1 ATR MCM7 CLSPN MCM3 CDC25C TOPBP1 CHEK1 ORC6 PSMD4 PKMYT1 BRIP1 BLM CDK1 PSMB5 DNA2 PSMC4 PSMA5 RAD9A PSME2 PSMD2 CDC7 RAD50 PSMB3 RPA1 UBE2V2 MCM6 MCM5 UIMC1	up	***
GO_BMP_BINDING	0.0022524	0.0234341	0.4317077	-0.7839110	-1.963038	8	SOSTDC1 GREM2 ENG BMPR2 TCAP	down	*
chr3q21	0.0000307	0.0007190	0.5573322	0.4823727	1.962078	74	FAM86JP MUC13 RUVBL1 KBTBD12 CHCHD6 ALDH1L1 IFT122 CCDC14 ACAD9 MCM2 UMPS PODXL2 ALG1L COPG1 RPL32P3 EFCAB12 CCDC58 SEC61A1 FAM162A PLXNA1 EEFSEC MGLL DUTP1 WDR5B SNX4 SLC12A8 SNORA7B KIAA1257 MBD4 PARP9 ROPN1B RCC2P4 PARP14 HMCES SLC41A3 DTX3L	up	***
GO_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.0000000	0.0000027	0.7195128	-0.3627884	-1.961945	202	ANGPT4 ACVRL1 SASH1 HMOX1 TEK PPARG GLIPR2 GATA2 EMP2 BMPER CORO1C BMPR2 TBXA2R FGF10 MIR27B TGFBR2 RHOA ANXA1 MIR146A MMRN2 PTPRM HBEGF ARSB ADAM17 HSPB1 FOXP1 ADIPOR1 GATA3 RGCC NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NUS1 ANXA3 MAPRE2 TGFB2 PRCP JUN NOTCH1 ETS1 MAP4K4 RHOJ PRKCE PPM1F PLCG2 EPPK1 TGFB1 MIR23A CLASP2 MACF1 CCR6 FGF2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 SP100 EPHA2 GLUL EDN1 PTEN FGFR1 NRP2 FLT4 STARD13 CTSH HAS2 MIR640 MIR2355 CALR WNT5A ANGPT2 HMGB1 ATOH8 DOCK5 SIRT1 PTGS2 SEMA5A CAPN7	down	***
LIM_MAMMARY_LUMINAL_MATURE_DN	0.0000299	0.0007028	0.5756103	-0.4099963	-1.961874	89	WTIP DPYSL2 LPL AQP9 TGFBR3 GAS6 FAM49A LTBP4 SFRP1 TUBB6 EPB41L2 FABP5 TLE4 FOXO1 SORBS1 CASP1 NES DAB2 VIM RECK FRMD4A RASL12 FOXN3 KCTD12 ETS1 MAP4K4 GYPC ZNF521 CYGB IRS2 MOB3B SPARCL1	down	***
GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN	0.0000002	0.0000075	0.6901325	-0.3723860	-1.960799	170	SLC31A2 ACP5 KMO TSPAN4 PECAM1 PTPRE LIPA ENG FIG4 PLEKHA1 YPEL5 IGSF6 TXNIP SLC7A7 CLEC7A IFI30 HLX SIRPA GRN ARRB1 CCL22 SRSF5 DAAM2 CDKN1A CD302 LBH FCER1G PIK3C2A PLEK PINK1 HCK VAMP3 CTSS CD48 CTSZ TYROBP CD83 HERC1 RHOQ TNFSF13 KAT8 TIMP2 MILR1 TSC22D1 CD86 CD81 LGALS3 CCR1 FCGRT N4BP2L2 ARAP2 RTN1 CXCR4 RIPK2 DHRS12 TBC1D1 METTL7A LIMCH1	down	***
GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_UP	0.0000001	0.0000053	0.7049757	0.4324282	1.959584	175	TRIP13 FANCI TROAP CCDC34 UBE2T CPSF6 NDC80 DEPDC1 DEPDC1B IQGAP3 GTSE1 IFT122 KIF14 STIL CDCA8 ECT2 ESPL1 TPX2 ARHGAP33 TYMS PRC1 CCNF DCTN2 CCDC150 MELK SPAG16 EME1 SAE1 KIF2C E2F2 POC1A CDCA5 RAD54L GPSM2 WDR66 CDC25C CKAP2L PKMYT1 CKS1B CDKN2C HPS4 NUSAP1 CBX5 HDGF CENPJ BIRC5 SPAG5 SAPCD2 DIAPH3 RANGAP1 CCNE1 TRIM24 DLGAP5 TACC3 DTYMK GINS2 TCEA1 SPA17 TAPT1-AS1 CDC7 PEX5 UBL7-AS1 MRPL51 CYTH2 PRDM10 CARHSP1 ARHGAP11A SRP9 RPRD2 MXD3 TCF3 SEPHS1 CDC25B TUBA1C ZNF367	up	***
LINDSTEDT_DENDRITIC_CELL_MATURATION_A	0.0001895	0.0032866	0.5188481	-0.4467026	-1.958254	57	IL1B IL1RN SCARF1 PLA2G7 ENTPD1 SLC7A11 TFEC CD58 CCL3 CXCL2 CCL4 PLEK INHBA IL7R HCAR3 IL6 CREM CD48 STAT4 PTGER4 MALT1 SLC3A2 SOD2 KYNU CCL20 ICAM1 RTN1 RAB5A EDN1 TNFSF9 CSF2	down	**
REACTOME_DEFECTIVE_GALNT3_CAUSES_FAMILIAL_HYPERPHOSPHATEMIC_TUMORAL_CALCINOSIS_HFTC	0.0004853	0.0071718	0.4984931	0.7521983	1.957484	12	MUC5B MUC13 MUC4 MUC16 MUC5AC MUC20 MUC6	up	**
GESERICK_TERT_TARGETS_DN	0.0025635	0.0258499	0.4317077	-0.5883635	-1.956984	19	EGR2 HBEGF BTG2 KLF10 NR4A1 KLF4 KLF9 JUNB FOSB DUSP6 ZFP36 HEY1 NFIL3 NFKBIZ	down	*
SANA_TNF_SIGNALING_DN	0.0000360	0.0008207	0.5573322	-0.4311986	-1.956660	71	EPAS1 SASH1 ACE PECAM1 LYVE1 MMRN1 EMCN LDB2 CALCRL SRSF7 GIMAP6 TXNIP ANXA1 VWF ARHGDIB CABLES1 KCTD12 RHOJ PALMD CD34 ZNF521 CTNNAL1	down	***
GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION	0.0002855	0.0046798	0.4984931	0.6989697	1.956015	16	GINS1 POLE MCM4 LIG3 GINS4 POLD2 MCM7 MCM3 LIG1 DNA2 GINS2 GINS3	up	**
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_DN	0.0000004	0.0000163	0.6749629	0.4346215	1.955879	163	TRIP13 CDC45 MCM10 TROAP CCDC34 PBK PRIM2 DEPDC1 MRPL46 GINS1 CDK4 SNF8 PLK1 NUF2 CDCA8 AURKB SFXN1 CCNB2 FIGNL1 SHMT2 SPDL1 NME1 RANBP1 HMMR MKI67 KIF15 BUB1 AURKA EME1 MCM7 RRM2 ORC6 MAD2L1 CKAP2L RAD51AP1 SPC24 DSCC1 CKS1B ASF1B CDK1 POLE2 UCK2 BIRC5 GMNN ADAP1 POLR3K SLC25A13 PSAT1 SPAG5 ETFB CENPP TUBG1 PSMA5 KIF22 AGPAT5 PRMT7	up	***
GSE8515_IL1_VS_IL6_4H_STIM_MAC_UP	0.0000002	0.0000088	0.6901325	-0.3746248	-1.955601	158	CXCL3 DENND5A IL1B CCRL2 CDH13 PAFAH1B2 STX11 ALAS1 NCF2 SCARF1 RFTN1 LYRM4 BTG2 PTX3 SERPINB9 BTG3 TCF7L2 PPP3CC NFKB1 DOCK9 CXCL2 CCL4 UXS1 CCSER2 PLEK TP53BP2 MAFF SNN BTG1 KANK1 PKIG HCAR3 FRY CD80 IL6 FAM189A1 PSEN1 STAT4 PLK3 JUNB WTAP PTGER4 CCR7 CD83 REL ACSL1 EHD1 PDE4B CCL20 ICAM1 RIPK2 SIK3 TRAF1 MAP3K4 NFKBIA TNFSF9 GPR171 SYNPO2L	down	***
REACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION	0.0039134	0.0356718	0.4070179	-0.7462576	-1.955211	9	TXNIP TXN FOXO1 FOXO3 KAT2B CREBBP EP300 SIRT1	down	*
GROSS_HYPOXIA_VIA_ELK3_DN	0.0000012	0.0000451	0.6435518	-0.3873600	-1.954873	134	CXCL3 SLPI RAMP3 MNDA PRKG2 THBD CD44 TXNL1 NEDD4L NEDD9 TSHZ1 USP47 HBEGF ANPEP KLF6 SLC7A11 TRAF6 CD93 SPRY2 SRGN CSRNP1 KLF4 CXCL2 ATF3 EPS15 PLEK ADIPOR2 AFF1 ZNF330 RBPJ GZF1 IL6 ETS1 RCAN1 PPP1R15A PTGER4 SKIL IFRD1 FOS TGIF1 PDLIM5 CDC42EP3 ACAP2 RND1 NFKBIA JMJD1C EDN1 SAMSN1 ATF4 RABGEF1 PIM3 EGR1 CHIC2 S100A8 ZFP36 BCL10 SCAF11 AKAP12 NFIL3 MAP3K1 CSF3 ITGA6 PTGS2	down	***
GO_PRI_MIRNA_TRANSCRIPTION_BY_RNA_POLYMERASE_II	0.0005106	0.0074767	0.4772708	-0.4760124	-1.954822	42	SMAD6 PPARG GATA2 BMP2 FOSL1 NR3C1 NFATC3 SPI1 IL10 KLF4 TGFB2 SRF JUN ETS1 DDX5 FOS TGFB1	down	**
GO_PEPTIDYL_SERINE_DEPHOSPHORYLATION	0.0021206	0.0224342	0.4317077	-0.5806523	-1.954655	20	SWAP70 PPP1R15B PPP2R2A PPP3CA DUSP1 PPP2CA PPP1R15A PPM1F PPTC7 PPP2CB	down	*
GO_POSITIVE_REGULATION_OF_ERAD_PATHWAY	0.0013525	0.0160660	0.4550599	-0.6709989	-1.954638	13	ATXN3 CAV1 EDEM1 NFE2L2 RNFT1 UBQLN1	down	*
chr7q34	0.0002685	0.0044379	0.4984931	0.5550178	1.954135	38	ATP6V0A4 PRSS2 RN7SL481P TTC26 AGK CASP2 RAB19 TRPV6 SLC37A3 TMEM178B SSBP1 MKRN1 UBN2 GSTK1 KIAA1549 MRPS33 TAS2R3 RN7SL535P ADCK2 ZC3HAV1L	up	**
GO_ATPASE_ACTIVITY_COUPLED	0.0000000	0.0000004	0.7614608	0.4137661	1.954120	257	KIF1A DDX11 HELLS DDX12P RUVBL1 CDC45 DNAH2 POLQ KIF18B TTF2 PIF1 GINS1 KIF14 FIGNL1 MCM4 MCM2 RAD54B DNAH3 XRCC2 DYNC1I1 MCM8 GINS4 DNAH14 DNAI1 RUVBL2 TNNT2 HLTF KIF3B TOP2A MYO10 SMARCAL1 MCM7 WDR78 HELB RAD54L KIF11 MCM3 PEX6 WDR60 CHD6 DNAH8 DSCC1 DNAH11 BRIP1 BLM ERCC2 MNAT1 RECQL5 DDX56 NSF DDX51 DNAH6 KIF5A NAV2 DHX37 KIF19 DNA2 DHX33 DYNLL2 DNAH5 PSMC4 RECQL4 DHX34 MOV10 DNAH7 DHX40 LONP1 RAD51D CHTF18 GINS2 KIF20B CHD5 ATAD5 RAD50 EP400 WDR34 FANCM MCM6 CHTF8 DHX8 MCM5 DNAI2 ZRANB3 DDX23 DYNC2H1 KATNB1 IGHMBP2 MYH3 DDX55 MSH4 MSH2 SMARCA4 DDX54 RTEL1 RFC5 DNAH1 RAD51 SNRNP200 CHD3 SRCAP DDX52 HSPA7	up	***
GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS	0.0000024	0.0000809	0.6272567	0.4518322	1.954050	120	SPICE1 CHEK2 NEK2 CCNB1 NDC80 TTK RACGAP1 STIL MSTO1 PLK1 NUF2 AURKB CENPA ESPL1 TPX2 MYBL2 PRC1 DCTN2 SPDL1 WDR62 KIF23 KIF3B MAP10 AURKA TPR POC1A FSD1 KIF11 GPSM2 MAD2L1 SPRY1 PSRC1 NUSAP1 CEP97 BIRC5 KIF2A SAPCD2 KPNB1 CEP192 TUBG1 TACC3 CDC20 TUBG2 AAAS EFHC1 CHMP4C CDK5RAP2	up	***
SA_MMP_CYTOKINE_CONNECTION	0.0023278	0.0240409	0.4317077	-0.6580994	-1.953898	14	ACE SPN IL1B CD44 TNFRSF8 SELL TGFB2 TGFB1	down	*
GO_PHOSPHATIDYLINOSITOL_PHOSPHATE_PHOSPHATASE_ACTIVITY	0.0021714	0.0228771	0.4317077	-0.5803969	-1.953795	20	FIG4 INPP5K PTPMT1 MTMR6 SACM1L INPP5B PIKFYVE MTMR14 MTMR2 PTEN	down	*
GNF2_PAK2	0.0014469	0.0167450	0.4550599	-0.5478802	-1.953757	25	MYD88 BNIP2 SELL ACTR3 CD53 ARHGDIB ACTR2 GMFG ADAM10 ACAP2 ARPC5 PAK2 CNOT8	down	*
GO_INTERLEUKIN_6_PRODUCTION	0.0000239	0.0005826	0.5756103	-0.3879139	-1.953266	112	EREG IL1A SCIMP SIGLEC16 IL1B LPL MYD88 IL1RN GAS6 CD36 MIR146A CLEC7A SIRPA TRAF6 ARHGEF2 IL10 ARRB1 PTAFR SOCS5 TLR4 FCER1G NCKAP1L IL17D IL6 TYROBP KLF2 AZI2 MBP CD74 AKIRIN2 SYT11 IL18 IL18RAP ARRB2 RIPK2 HAVCR2 BANK1 CYBA C5AR2 TREM2 TBC1D23 WNT5A BCL10 HMGB1	down	***
GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP	0.0000007	0.0000287	0.6594444	-0.3759597	-1.952833	160	HSPB7 ATXN3 BACH1 YPEL5 RPL23AP53 KCNN3 NR3C1 NUMB EIF4A1 CHMP1B PICALM ANXA5 SIRPA NFE2L2 AKT3 TMEM41B ZFYVE16 BTG3 UBE2D3 MOAP1 MEFV SNIP1 PNRC1 ZBTB43 UBE2B PER1 DNTTIP2 MATK IL7R SMNDC1 USP16 TOPORS NINJ1 DCP1A FLT1 IL6 COPS2 GABPA PHF10 ARHGEF10 DHX15 AGFG1 SLC3A2 ADNP2 AZI2 USP7 NAPG BTBD7 TEX14 PIK3C3 GATA6 PHF2 RXRA ZNF143 CEP170 SF1 MEX3C NABP1 SFPQ DNAJB5 RABGEF1 ADAMTS7 UBAP1 UBA6 ZYX ECD ZNF654 UBE2W UBE3A DDX21	down	***
WONG_ADULT_TISSUE_STEM_MODULE	0.0000000	0.0000000	1.0073180	-0.3227207	-1.952775	583	CXCL3 RAMP3 SASH1 STAC TEK TSPAN4 PDLIM2 DLC1 TAL1 OSBPL1A KCNA2 GATA2 IL1B TIE1 F2RL3 SNX10 THSD1 ADCY9 GPR65 LRRFIP1 ENG BDNF FYN SHANK3 EGR2 LMO2 BACH1 CAV1 MYADM CITED2 SLC39A8 ESAM MEF2A CASP12 NEDD9 ABCB1 SPCS3 IER2 PDE2A NFIX HBEGF CACNA2D2 LATS2 ENTPD1 EIF1 PLXNA2 ABCG2 CLEC7A GNGT2 AHRR PBX3 ZNF503 ABCG1 KLF10 FOXP1 KLF6 HLX GATA3 NR4A1 ADRB2 IL18R1 SFRP1 PPP1R13B CLK1 ZEB1 BTG3 TXN PDGFA TUBB6 RHOB LRP4 ADARB1 PTPN12 SYNPO PTPN21 KCNMA1 KLF4 AOC3 PEG3 REST KLF9 DAB2 USP2 STK17B THBS1 SOCS2 MYO1B MPL CLIC4 TMBIM1 ITIH5 PDE8A CCL3 CDKN1A CADM1 UBE2E2 ATF3 SELP ID2 PTGER3 PER1 DUSP1 SMAD7 PLEK MATN2 SLC6A6 GNAQ PRDM5 CRIM1 MEDAG VWF PROCR CREBRF SLC8A1 HCAR3 ID4 IL6 PHTF2 KLRB1 SOCS3 MAGI2 RGS18 SLC35E4 JUN MITF STAT4 LTBP2 CTSZ HSPA1B JUNB ARHGEF10 IFNGR1 JAK1 AK1 DUSP8 PPP1R15A PTGER4 FERMT2 DAPK2 PRKCE GRASP GRIK1 CD34 ACOT1 SLC3A2 FOS RHOQ RRAS KLF2 PKD2 FOSB DGKG PKIA ZNF521 TCF4 CD1D GLRA3 TSC22D1 CBFA2T3 MEIS1 GABARAPL1 TOB1 MFNG MACF1 RGS2 LTBP1 TAGLN ETS2 DBNDD2 ICAM1 SESN1 HSPA2 IL18 CPQ SERTAD1 CEBPD MS4A4A CDKN1C ITGAE TRAF1 S100A4 LYSMD3 GLUL LIMCH1 NFKBIA TTC28 KIT TIMP3 SKI LTBP3 MCOLN2	down	***
STK33_SKM_UP	0.0000000	0.0000006	0.7477397	-0.3562349	-1.952300	235	NLRC4 KMO IL1A HMOX1 SLC12A6 CD101 OLR1 OSBPL11 SOWAHC CPEB2 IL1B FABP4 LPXN GPR65 MIR22HG THBD PID1 C5AR1 BCL2A1 NCF2 CD9 TRIB1 FGR CD36 ANXA1 SH2B3 PTPRM HBEGF HECW2 BTG2 KLF6 SLC7A11 RGCC CRK TFEC CD58 RHOB CYBRD1 PTPRO MPEG1 LY96 RIT1 CDKN1A CCL4 CD53 DUSP1 EMP3 CREBRF SGK1 RNF141 NECAP1 ARL5B CPEB4 TYROBP JUNB DUSP8 SKIL GLIPR1 GPR183 SUCNR1 FAM177A1 ZNF407 FOS BTBD7 NAPSB MILR1 CDC37L1 DUSP5 TGFB1I1 CD86 TMEM107 HINT3 STX12 NBEAL1 RGS2 EPB41L5 CALHM2 TFPI RTN1 CDKN1C TMOD2 TTLL7 STAM2 TLR10 NFKBIA	down	***
GO_MAP_KINASE_PHOSPHATASE_ACTIVITY	0.0013764	0.0162382	0.4550599	-0.6700869	-1.951981	13	DUSP3 DUSP1 DUSP8 DUSP5 PP2D1 DUSP7 DUSP6 DUSP2 DUSP10	down	*
GSE20715_WT_VS_TLR4_KO_LUNG_UP	0.0000002	0.0000081	0.6901325	-0.3687588	-1.951589	172	RBP4 EPAS1 TMEM100 LRRC8C FIG4 TMOD3 PCOLCE2 PRKAR1A MEF2A CD9 SEMA6D CD36 ANXA1 SSTR1 RAPGEF4 SERINC1 HSPB1 EIF4E BTG3 UBE2D3 PDGFA FBXO8 MTMR6 TBX4 NPNT ST3GAL2 ITM2B MAP1LC3B CLIC4 VIM CD302 CD53 CPT1A RNF149 SNAP23 GLUD1 JAK1 SNX2 PIK3R1 DDX5 MME SERPINB1 KCTD10 FPR2 ORC2 CSDE1 MR1 MBNL1 SOD3 GPX3 RTN4 CUL3 SAMSN1 TMCC3 GSPT1 GIMAP4 RNF13 DNAJA2	down	***
GNF2_CDH3	0.0002802	0.0046054	0.4984931	0.6353196	1.951524	23	COL17A1 GPR87 TP63 S100A2 FERMT1 LAMC2 GJB3 CDH3 KRT19 AHNAK2 PTHLH FGFBP1 KRT17	up	**
GO_DNA_UNWINDING_INVOLVED_IN_DNA_REPLICATION	0.0003213	0.0051589	0.4984931	0.7249614	1.951280	14	MCM4 MCM2 MCM7 BLM RECQL5 SSBP1 RECQL4 HMGA1 RPA1 MCM6 RAD51	up	**
GO_POSITIVE_REGULATION_OF_INTEGRIN_MEDIATED_SIGNALING_PATHWAY	0.0009726	0.0124603	0.4772708	-0.8171299	-1.950409	7	LIMS2 EMP2 LIMS1	down	*
MIR122B_3P	0.0000343	0.0007910	0.5573322	-0.3926124	-1.950104	104	GCOM1 ZC3H12C CPEB2 RDX HSD17B11 RTN3 LAMP1 SRSF2 HERC3 GPM6A CDADC1 PEG3 RUNX1T1 C9orf72 KIRREL3 SMAD7 TOPORS PSEN1 APPL1 WTAP FYTTD1 RC3H1 SNRK CDK14 CDK17 FOXO3 CCDC85A NAP1L5 BTBD7 ING3 PDE4B TIAM1 POLR2M PRKG1 MMD CAMSAP2 ZNF326 USP4 CHIC2 TMEM43 ZNF800 ATP1B1 DNAJB4 TSC22D2 MAP3K1	down	***
DUNNE_TARGETS_OF_AML1_MTG8_FUSION_UP	0.0005899	0.0084351	0.4772708	-0.4677711	-1.950092	44	CAT SPCS3 LCP1 SRGN LAPTM5 CD302 ALOX5AP GCA LIN7A BTG1 TRGC2 PTGER4 CST7 ALDH3B1 NKG7 SELPLG CXCR4 ICAM3 SAMSN1 LYZ FNBP1 S100A8	down	**
REACTOME_HDR_THROUGH_HOMOLOGOUS_RECOMBINATION_HRR	0.0001524	0.0027403	0.5188481	0.4928372	1.950034	63	BRCA1 POLE RBBP8 XRCC2 EXO1 RHNO1 EME1 ATR POLD2 EME2 TOPBP1 CHEK1 RAD51AP1 BRIP1 BLM POLE2 DNA2 RAD9A RAD51D POLD1 SLX4 RAD50 PALB2 RPA1 RTEL1 RFC5 RAD51 RAD1 MUS81 SPIDR TOP3A ATRIP RMI1 POLD3 RMI2 RAD51B RFC3 BARD1 POLE4 RFC4	up	**
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN	0.0000002	0.0000087	0.6901325	-0.3703271	-1.949958	170	SLC31A2 ACP5 CD52 HMOX1 CD101 OSBPL11 PECAM1 HHEX MNDA LTA4H HSD17B11 MYD88 MSRA FUCA1 FRAT1 TMX4 CD36 TNS1 GRN EVI2B KIAA0513 KLF11 ARNTL VRK2 ITPK1 PAPSS1 EVI2A CPT1A MBD2 MPC1 VAMP5 KBTBD4 HEXB NCKAP1L PRCP ARL6IP5 RNF141 IDS RASSF2 CELF2 ICAM2 BIN2 SORT1 TIMP2 RPL21 CD86 MAP3K2 THAP11 CLEC2B PCCA COMMD9 BMP2K VASH1 CALHM2 CEBPD ALDH2 TBC1D1 IFFO1 METTL7A GLUL THEMIS2 CNOT8	down	***
MIR21_3P	0.0000283	0.0006679	0.5756103	-0.3931281	-1.948345	102	GCOM1 ZC3H12C CPEB2 RDX HSD17B11 RTN3 LAMP1 SRSF2 HERC3 GPM6A CDADC1 PEG3 RUNX1T1 C9orf72 KIRREL3 SMAD7 TOPORS PSEN1 APPL1 WTAP FYTTD1 RC3H1 SNRK CDK14 CDK17 FOXO3 CCDC85A NAP1L5 ING3 PDE4B TIAM1 POLR2M PRKG1 MMD CAMSAP2 ZNF326 USP4 CHIC2 TMEM43 ZNF800 ATP1B1 DNAJB4 TSC22D2 MAP3K1	down	***
ROSS_AML_WITH_MLL_FUSIONS	0.0002437	0.0040701	0.5188481	-0.4312103	-1.947682	65	FBP1 SNX10 ADCY9 LY86 GGA2 SPG21 PBX3 ANXA5 DACH1 SIRPA CES1 SRGN SOCS2 TPP1 ITGAX ALOX5AP TDRD7 HEXB HK3 APH1B ALDH3B1 NKG7 WHAMMP3 MBNL1 SCPEP1 RNH1 FEZ1	down	**
GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_UP	0.0000011	0.0000397	0.6435518	-0.3787809	-1.947137	145	RAB11FIP1 EREG IL1A OLR1 SOWAHC PGC IL1B LRRC8C NUP54 EGR2 CRY2 FXYD2 SLC15A3 DYRK1A LRRFIP2 CD33 ZDHHC2 SLC7A11 NR4A1 SRGN SLC7A2 CSRNP1 BST1 SLC12A4 PDE8A CCL3 MGAT4A CXCL2 CCL4 HTRA4 KREMEN1 RBPJ FMNL2 NOTCH1 TREM1 DUSP8 OSM RNF24 EGLN2 ACSL1 AGFG1 SIGLEC1 MBP CD74	down	***
REACTOME_IRAK4_DEFICIENCY_TLR2_4	0.0042265	0.0377893	0.4070179	-0.7431339	-1.947027	9	MYD88 CD36 LY96 TLR4	down	*
GO_CHROMOSOME_SEPARATION	0.0000272	0.0006462	0.5756103	0.4716443	1.946276	81	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDC6 NCAPD2 CDT1 SPDL1 BUB1 TOP2A EME1 TPR MAD1L1 EME2 MAD2L1 RECQL5 ANAPC5 DIS3L2 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 SLX4 CDC20 FANCM CDK5RAP2	up	***
GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_DN	0.0000002	0.0000097	0.6901325	-0.3656588	-1.946090	177	CXCL3 STAC PHACTR1 SOWAHC IL1B RDX TXNL1 CCRL2 ARL8B IL1RN AGPAT4 RFTN1 PLA2G7 RRAGC HBEGF LMNA GM2A MTF1 SLC7A11 CLN5 ZFYVE16 TXN ATP6V1H TUBB6 CCL22 PXDC1 DAB2 ATP6V1D MAFG CDKN1A CXCL2 CCL4 ZBTB43 INHBA IL7R MAFF CRIM1 PI4K2A MMP19 CLN8 NINJ1 IL6 MITF STAT4 SH3BP5 GSTO1 WTAP CCR7 UNC13B ATP13A3 SLC3A2 RHOQ HIVEP2 TSC22D1 PIM1 SOD2 KYNU ZNF267 ETS2 ANKLE2 TEX10 TRAF1 BCAT1 GLRX2 PDE4A CAMSAP2 DOCK4 MT2A	down	***
GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN	0.0000002	0.0000093	0.6901325	-0.3676253	-1.945590	172	SLPI PECAM1 LPXN THBD LMO2 GPCPD1 S1PR1 STX11 GNPTAB CD22 NFATC3 CD36 B3GNT5 ZDHHC2 RANBP9 FOXP1 RB1 TMEM123 CD93 HERC3 FBXL5 TAPT1 DGKE PRKD3 PLEKHM3 ATP6V1D CCND2 PPP2R5A HLA-DQA1 AFF3 SNN PIAS1 ARHGAP17 PKIG ELF1 WASF2 CTSS SLC14A1 OSTM1 WTAP CCR7 STX7 UBAC2 PRKCE FRYL TINF2 GPR3 PRKCG CD74 FAM204A PIK3AP1 VAV3 KCNA3 RGS2 GPR18 BMP2K ANKLE2 HSPA2 ALDH1B1 SPIB RIPK2 B3GNT2 CECR2 CYTH1	down	***
HOLLERN_EMT_BREAST_TUMOR_UP	0.0000074	0.0002166	0.6105269	-0.3850968	-1.944928	123	TSPAN4 ADPRH HHEX CDH13 TGFBR2 SCARA3 HSPG2 NAAA ITGA5 CSGALNACT2 TTYH2 HLX IL18R1 SPTBN1 ZEB1 SPI1 EPB41L2 ST3GAL2 DAB2 STK17B MARVELD1 GPR85 VIM AXL MATN2 MEDAG NRROS EMP3 ARL6IP5 PLEKHA3 RGS18 APBB2 GLIPR1 SNX9 FLNC TIMP2 APBB1 AOX1 GNB4 FCGRT PLA2G15 FAM167B OSR1 TRAF1 S100A4 NRP2 ZFPM2	down	***
GO_REGULATION_OF_CELL_SUBSTRATE_JUNCTION_ASSEMBLY	0.0002457	0.0040956	0.4984931	-0.4434126	-1.943831	57	ACVRL1 TEK DLC1 WNT4 CORO1C RHOA APOD SFRP1 ROCK2 DUSP3 LIMS1 ROCK1 THBS1 PEAK1 FAM107A MAP4K4 PPM1F EPHA3 CLASP2 MACF1 EPB41L5 LIMCH1 PTEN IQGAP1 GREM1	down	**
GO_REGULATION_OF_CHROMOSOME_SEPARATION	0.0000534	0.0011405	0.5573322	0.4994941	1.942795	59	TRIP13 BUB1B CCNB1 CENPF NDC80 TTK PLK1 AURKB PTTG1 ESPL1 CDC6 CDT1 SPDL1 BUB1 TPR MAD1L1 MAD2L1 ANAPC5 MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 ANAPC1 CDC20 CDK5RAP2	up	**
GO_PROTEIN_LOCALIZATION_TO_MICROTUBULE_ORGANIZING_CENTER	0.0003420	0.0054423	0.4984931	0.5902405	1.942527	30	CEP72 NUDCD3 CCDC14 STIL GOLGB1 DCTN2 CEP250 BICD1 AURKA C2CD3 KIAA0753 SPAG5 CEP192	up	**
GO_NEGATIVE_REGULATION_OF_INTERFERON_GAMMA_PRODUCTION	0.0008977	0.0116875	0.4772708	-0.5361568	-1.942152	26	IL1RL1 GAS6 GATA3 IL10 AXL TLR4 MIR24-2 INHBA	down	*
GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP	0.0000008	0.0000329	0.6594444	0.4275703	1.941521	177	RUVBL1 CDC45 MCM10 CENPF NUDCD3 TSFM GINS1 RACGAP1 POLE TTC26 PLK1 CDCA8 CENPA GAPDH MYBL2 DTL CDT1 CCT2 SPDL1 HAUS5 BZW2 EXO1 MKI67 KNTC1 POLD2 RBM28 PDCD5 LIG1 BLM MEOX1 CNPY2 CKS1B NCAPG2 TMEM106C PABPN1 EXOSC2 ATIC POLR3K FBXO41 MCAT MRPL17 MRPS12 RNASEH2A ILF2 ATP6V0E2 TACC3 LONP1 DTYMK SPAG1 MAGOHB CCT7 RAD50 SUPT16H NPRL3 DUS1L POP7 FAM136A BCL2L1 MRPL24 NOC4L GINS3 LSM4 PRKD2 PRMT5 MICAL3 PMS1 GRAMD1B RPUSD2 CIAPIN1 TARBP2 LIF NMT1 NCAPD3 ENO1 NUP210 DNM1L NUP93 COX17 WRAP73 SRM BAG2 CLPP HINT1 TMPO IMP4 DCLRE1A CS HNRNPAB CRCP NUP37 FIBP CTPS1 TMEM14A	up	***
GO_MYELOID_LEUKOCYTE_ACTIVATION	0.0000000	0.0000000	0.9545416	-0.3190075	-1.940864	535	SIRPB1 SLPI CD300LF FOXF1 HMOX1 FCN1 OLR1 PECAM1 HVCN1 CD55 GATA2 MNDA LTA4H DCSTAMP CAT RAB44 CLEC12A PLA2G10 PTPRB OSCAR CD44 PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA IL1RL1 VAPA FUCA1 LAMP1 CBL SLC11A1 TGFBR2 LILRB3 FGR RHOA DNASE1L3 CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ASAH1 RAP1A GM2A FOXP1 ANPEP PTX3 STOM LAIR1 SIRPA TRAF6 CD93 GRN LAMTOR3 SPI1 RAB14 CD58 CST3 SLC7A2 IL10 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 THBS1 CEBPA ATP6V1D CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE TLR4 ARHGAP9 CD53 FCER1G GCA DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP RBPJ IL6 CTSS PSEN1 SNAP23 C1QA JUN VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG IFNGR1 ENPP4 GLIPR1 GMFG PRKCE SERPINB6 CAP1 SUCNR1 CST7 PSMD12 ALDH3B1 TREX1 CD74 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 DOK3 JMJD6 MILR1 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ORM2 BRI3 PLEKHO2 ADAM10 IST1 SYT11 COMMD9 UNC13D IL18 IL18RAP LAT HSP90AA1 HSPA8 HAVCR2 METTL7A NHLRC3 KIT SIGLEC9 CTSC ARPC5 SNAP29 P2RX1 RORA LDLR PSMD6 IQGAP1 CREG1 CNN2 ANO6 LYZ SPHK1 CSF2 CYBA ATP6V0A1 CTSH CNR2 TMEM30A ATP11B MAPK1 ITGAL TREM2 FTL S100A8 RAB37 FPR1 KMT2E NFAM1 PIK3CG	down	***
MODULE_252	0.0000000	0.0000020	0.7195128	0.4156144	1.940473	219	CCNO TRIP13 FOXM1 CDC45 NUP107 NEK2 COIL CCNB1 CENPF NDC80 PRIM2 CDK4 PLK1 CENPA PTTG1 SOX9 E2F3 CCNB2 MYBL2 ORC1 NCAPD2 ZWINT NME1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A POLD2 KIF2C MSX1 PRKDC WDHD1 RAD54L ZNF146 MCM3 CHAF1B LMNB1 CDC25C SOX4 LIG1 TOPBP1 ACTL6A MAD2L1 NFYA CDKN2C CBX5 CDK1 POLE2 BIRC5 E2F1 UNG PSMB5 FEN1 EZH2 TAF6 SNRPE CBX1 PSMC4 VPS72 RECQL4 DNMT1 ILF2 RAD51D SSRP1 NFATC4 HDAC1 SAP30 POLD1 PSMD2 CDC7 POP7 RPA1 MCM6 STAMBP SRPK2 SNRPD1 DDX23 NEK4 SRSF1 KATNB1 RCC1 MSH2 CCNA2 PRIM1 STK38 RFC5 RAD51 ZNF217 SMC2 CENPE APEX1 SNRPC PNN TAF4 PPP2R5D KRT17	up	***
GO_MICROVILLUS_MEMBRANE	0.0004732	0.0070252	0.4984931	0.6580810	1.940016	20	CEACAM1 CDHR2 CA9 PROM1 PTPRH MUC20 SLC9A3R1 PROM2 SLC26A2	up	**
KEGG_PYRIMIDINE_METABOLISM	0.0000184	0.0004694	0.5756103	0.4653852	1.939825	90	PRIM2 POLE TYMS UMPS DPYS NME1 POLR3A POLA2 POLD2 RRM2 NT5C1B ENTPD6 NME5 POLR3C CAD ENTPD5 POLE2 UCK2 NUDT2 POLR3K POLR1C UCKL1 POLR2H UPP2 DHODH TK1 DTYMK POLD1 NT5M ENTPD8 POLR2J ENTPD3 POLR2J3 POLR2I NME1-NME2 PRIM1 CANT1 POLR3B NME4 NME7 POLR1B POLR1A	up	***
GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN	0.0000002	0.0000072	0.6901325	-0.3647368	-1.939491	176	HSD17B11 LMO2 CCRL2 ST3GAL6 BCL2A1 CD22 ANXA1 SPG21 ENTPD1 PPP1R15B SERPINB9 GATA3 IL18R1 SRGN BTG3 UBE2D3 RAB14 AHNAK MPEG1 RNFT1 ITM2B ARNTL SOCS2 GRK5 PLBD1 FAM49B HOPX ID2 PLEKHB2 PRF1 EVI2A VAMP5 IL7R SMNDC1 HLA-DQA1 ACTR2 HGSNAT SACM1L ASNSD1 NXF1 KCTD12 ETS1 PTGER4 EEA1 RASSF2 RIN2 IRF5 AP1G1 SBF2 RELL1 DOK2 GNA13 RGS2 SERINC3 PPID ICAM1 IL18RAP SFT2D1 ARIH1 G3BP2 OSER1 CD19 CUL3 KLRK1 DNAJB9 NABP1 SPATA13 EIF4G2 CYBA CTSH	down	***
NIKOLSKY_BREAST_CANCER_6P24_P22_AMPLICON	0.0024507	0.0249881	0.4317077	-0.5761379	-1.939458	20	PHACTR1 GFOD1 TBC1D7 RNF144B RANBP9 RNF182 ID4 KIF13A CD83 NOL7 NUP153 MCUR1 TPMT	down	*
GO_ENDOCRINE_HORMONE_SECRETION	0.0009736	0.0124667	0.4772708	-0.5191755	-1.938920	30	RAB11FIP1 TBX3 IL1B HCAR2 FZD4 GATA3 TACR2 INHBA RAB8B CRY1 FGFR1 SMAD4	down	*
GO_NEGATIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.0002231	0.0037712	0.5188481	-0.4375275	-1.938310	60	ANGPT4 ACVRL1 PPARG CORO1C TBXA2R RHOA MIR146A MMRN2 PTPRM ADIPOR1 RGCC KLF4 THBS1 ADAMTS9 MIR24-2 NOTCH1 EPPK1 TGFB1 FGF2 VASH1 SP100 PTEN STARD13 MIR640 MIR2355 ANGPT2 HMGB1	down	**
chr18q21	0.0002270	0.0038241	0.5188481	-0.4373352	-1.937458	60	C18orf32 TXNL1 NEDD4L ZCCHC2 KDSR ELAC1 SMAD7 MBD2 RPL17 HAUS1 PSTPIP2 MALT1 MAPK4 DYM WDR7 MRPL37P1 TCF4 CCDC68 CTIF ME2 SMAD2 VPS4B MEX3C SMAD4 PMAIP1 EPG5 ZBTB7C PIAS2 IER3IP1 POLI	down	**
SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP	0.0000660	0.0013602	0.5384341	-0.4203871	-1.936868	74	CAT CASP9 TACC1 TRAF6 HNRNPDL MPHOSPH6 LAMTOR3 HNRNPU UBE2D3 TXN CASP1 PTPRC CUL5 SMNDC1 CTSS JAK1 TCP1 USP7 APBB1 PPP3R1 SOD2 CCR1 GPX3 HSP90AA1 UBE2D1 HNRNPK KPNA4 GLRX2 HAT1 CENPC ATF2 UBE3A UBE2N CUL2 ATF6 USP33 UBE2D2 RANBP2	down	**
chr7q36	0.0000365	0.0008284	0.5573322	0.4693010	1.936606	81	MNX1 PTPRN2 LINC00689 XRCC2 AOC1 NUB1 KCNH2 ZNF862 SMARCD3 SSPO WDR60 ZNF786 ZBED6CL LRRC61 REPIN1 NCAPG2 FASTK ATP6V0E2-AS1 ACTR3C PAXIP1-AS1 KRBA1 EZH2 ZNF775 ACTR3B WDR86 ATP6V0E2 YBX1P4 ATG9B SLC4A2 ZNF282 RBM33 ZNF783 TMUB1 PDIA4 ZNF212 ABCF2 VIPR2 PAXIP1 CDK5 TMEM176A CHPF2	up	***
GO_REGULATION_OF_DNA_REPAIR	0.0000345	0.0007943	0.5573322	0.4580959	1.936323	96	HMGA2 DDX11 FOXM1 EYA1 PARPBP EYA2 TIMELESS POLQ BRCA1 NPAS2 WDR70 FIGNL1 MAGEF1 TP53BP1 AUNIP PRKDC HELB EGFR CHEK1 RAD51AP1 XRCC1 PML RECQL5 PARP1 MAD2L2 MGMT NUDT16 PARP9 UBQLN4 TWIST1 UBE2V2 WRNIP1 UIMC1 DTX3L RTEL1 RAD51 EYA4 NUDT16L1 SIRT6 PARG	up	***
GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_12_PRODUCTION	0.0026153	0.0262156	0.4317077	-0.6520532	-1.935947	14	ACP5 IL10 MEFV THBS1 NFKB1 TIGIT ARRB2	down	*
BILBAN_B_CLL_LPL_DN	0.0010420	0.0131118	0.4550599	-0.4837305	-1.935689	38	MNDA FYN SRSF7 CCNL1 ANXA1 EIF4A1 KLF4 ID2 DUSP1 JUNB FOS BIN2 RGS2 ACAP2 FNBP4 KLRK1 SFPQ PMAIP1 DUSP22 ARGLU1 PNISR FGL2 PRNP CAPN3	down	*
MODULE_337	0.0002188	0.0037038	0.5188481	0.5135001	1.934968	51	MDM1 CDC45 CENPF SEMA4B ORC1 SRPK1 NCAPD2 NME1 KCNN4 NUP155 RRM2 SPEF2 ANKEF1 GPSM2 NFYA ALG3 UCK2 GMNN E2F1 NUP205 RAB6B SNRPA PLEKHA8 ACLY ALMS1 HLCS ARHGAP11A MRTO4 PLK4 UTP18 ADSL	up	**
GSE3565_DUSP1_VS_WT_SPLENOCYTES_UP	0.0000016	0.0000561	0.6435518	-0.3778947	-1.934827	146	SNX10 TTC7B CD44 MYADM IL1RL1 GNPTAB FAM49A ZEB2 ANXA1 CYP17A1 ARSB LATS2 ZDHHC2 LAIR1 IL18R1 PPT1 AHNAK TRIM46 PLEKHM3 CTSD ITGAX VIM HOPX ID2 CCL4 TEF PRF1 CALM2 EMP3 NDNF CCDC50 EEA1 DAPK2 COBLL1 TBX21 GPRIN3 NKG7 KLRC2 XYLT1 SMPDL3B CHPT1 GSAP ATXN1 LGALS3 POLK IL18RAP MS4A4A ARHGAP18 TOB2 HAVCR2 KLRK1 RORA GIMAP4 RSU1 CX3CR1 ITGAL ITGB1 PIK3CG ARHGEF12 ATP2B4 NFIL3 RPA2 DOCK5 CD226 TTC39B MYO1F MYO5A EMP1 TNFRSF1B ZC3H7A F2RL2 GZMK	down	***
GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN	0.0000003	0.0000119	0.6749629	-0.3653804	-1.933710	172	SMAD6 OLR1 PPARG IL1B MIR22HG THBD ENG FYN AATK RBM14 MEF2A EIF4A1 ADA LMNA CSRP1 ANPEP PTX3 LAIR1 SRSF2 MPHOSPH6 CRK TMEM41B TIPARP FABP5 HNRNPA3 LIMS1 PLAUR THBS1 CCL3 NFKB1 CXCL2 ATF3 CCL4 ZBTB43 DUSP1 ARL4A MATK ANXA3 PI4K2A SRF EMP3 KANK1 SERPINB8 SH3BP5 GAS2L1 MN1 RHOG PPP1R15A CD83 GPR183 YWHAZ PPM1F CALM1 FOSB	down	***
CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP	0.0026287	0.0262803	0.4317077	-0.5744223	-1.933683	20	CD55 INSIG1 SRSF7 HSPE1 ACSL3 JUNB ACSL1 FOSB HSPA2 NEK3	down	*
GO_SECRETORY_GRANULE_MEMBRANE	0.0000000	0.0000008	0.7477397	-0.3504657	-1.933471	240	SIRPB1 OLR1 PECAM1 HVCN1 CD55 RAB44 CLEC12A IZUMO1 PTPRB CD44 CAV1 VAMP2 C5AR1 MANBA VAPA CD9 LAMP1 SLC11A1 LILRB3 RHOA CD36 SLC44A2 CD33 RAP1A ANPEP CAV2 STOM LAIR1 SIRPA CD93 LAMTOR3 RAB14 CD58 FABP5 BST1 PTAFR PLAUR GAA STX3 ATP6V1D ABCC4 TMBIM1 ITGAX PTPRC SELL SELP CD53 FCER1G DEGS1 CMTM6 HGSNAT RAB6A NCKAP1L PRCP PSEN1 PHACTR2 SNAP23 CYB5R1 RAB31 TYROBP ATP11A RHOG ENPP4 GLIPR1 SERPINB6 ALDH3B1 CR1 MME SIGLEC14 TMX3 DOK3 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 APLP2 LGALS3 BRI3	down	***
BIOCARTA_CTLA4_PATHWAY	0.0014976	0.0172264	0.4550599	-0.6134810	-1.933462	17	CD80 PIK3R1 GRB2 CD86 CD3G ICOS HLA-DRB1 CD3E ITK CD3D PIK3CA CTLA4 PTPN11 CD247	down	*
FISCHER_G1_S_CELL_CYCLE	0.0000015	0.0000537	0.6435518	0.4291411	1.933359	165	MNX1 HELLS C1GALT1 MDM1 MCM10 BRCA1 CDCA7 E2F8 POLE YEATS4 CDC6 RBBP8 MCM2 CDC25A DLGAP1 DTL TMCC1 MAP2K6 CDT1 TRIM45 CASP2 EXO1 CHAF1A PAQR4 POLA2 E2F2 CLSPN RRM2 WDHD1 PASK MCM3 CHAF1B TOPBP1 CHEK1 DSCC1 BRIP1 BLM RNPC3 POLE2 GMNN E2F1 UNG FEN1 EZH2 RECQL4 ABHD4 FANCG CCNE1 MNS1 CENPQ GINS2 CDC7 USP18 AP3M2 MCM6 MCM5 ANKRA2 ANK3 ATAD2 MSH2 PRIM1 BBX ABHD10 RAD51 ZMYND19 WDR76 ADCY6	up	***
MODULE_198	0.0000000	0.0000003	0.7749390	0.4081319	1.932705	272	CCNO TRIP13 FOXM1 CDC45 TFAP2A NUP107 NEK2 COIL CCNB1 CENPF NDC80 PRIM2 SPDEF POLE PLK1 CENPA PTTG1 ESPL1 SOX9 E2F3 CCNB2 RBBP8 MYBL2 ORC1 NCAPD2 ZWINT NME1 SMARCC1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A POLD2 KIF2C MSX1 PRKDC SETDB1 RAD54L ZNF146 MCM3 CHAF1B LMNB1 CDC25C SOX4 LIG1 TOPBP1 CHEK1 ACTL6A MAD2L1 NFYA BLM TULP3 CDKN2C CBX5 CDK1 POLE2 E2F1 UNG PSMB5 FEN1 EZH2 TAF6 SNRPE CBX1 PSMC4 VPS72 RECQL4 KPNB1 DNMT1 FANCG ILF2 CCNE1 KIF22 RAD51D SSRP1 ADAR NFATC4 HDAC1 SAP30 KRT19 POLD1 PSMD2 CDC7 AP3M2 POP7 RPA1 MCM6 STAMBP SRPK2 SNRPD1 DDX23 NEK4 SRSF1 KATNB1 RCC1 BCL9 MSH2 CCNA2 PRIM1 ZNF195 STK38 GTF3C2 RFC5 RAD51 ZNF217 SMC2 CENPE APEX1 SNRPC PNN TAF4 PPP2R5D KRT17	up	***
GNF2_CD97	0.0010083	0.0128084	0.4550599	-0.5165274	-1.932453	31	GPR65 GIMAP6 LITAF OSTF1 PTPRC ID2 JAK1 PTGER4 PTGER2 BIN2 DOK2 CLEC2B SELPLG IQGAP1 CX3CR1 AOAH ITGAL MYO1F APOBR IL10RA CYTIP STK10 ADCY7	down	*
PID_PLK1_PATHWAY	0.0003390	0.0053983	0.4984931	0.5394829	1.932328	41	KIF20A BUB1B CCNB1 NDC80 PLK1 ECT2 TPX2 PRC1 BUB1 AURKA ODF2 SSPO CLSPN CDC25C SPC24 INCENP PAK1 CDK1 KIF2A TUBG1 NINL FZR1 CDC20	up	**
WINNEPENNINCKX_MELANOMA_METASTASIS_DN	0.0009450	0.0121614	0.4772708	-0.5110245	-1.931634	33	CLIC3 CLEC3B DPYSL2 CRY2 CLEC10A CD1C TXNIP RNF125 CST3 CEBPA ST6GALNAC6 LGALS2 TOM1L2	down	*
GO_CILIARY_TIP	0.0003074	0.0049941	0.4984931	0.5443946	1.931497	40	IFT122 TTC26 IFT27 KIF3B IFT43 WDR60 IFT172 KIF3C KIF7 DYNLL2 SMO IFT52 TRAF3IP1 WDR34 WDR35 DYNC2H1 ICK CLUAP1 TTC30B GLI3 KIFAP3 KIF3A IFT81 IFT74	up	**
chr17q12	0.0001488	0.0026798	0.5188481	0.4900154	1.930394	61	PPP1R1B STAC2 SLFN13 CCL8 GRB7 LIG3 NLE1 SLFN5 TADA2A TBC1D3 CDK12 C17orf78 SRCIN1 MYO19 RAD51D PSMB3 HNF1B SLFN12 HMGB1P24 AATF CISD3 MIEN1 MLLT6 ERBB2 SYNRG DDX52 SLFN12L CCL13 LASP1 PCGF2 RFFL AP2B1 PGAP3 CACNB1	up	**
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_23	0.0023511	0.0242132	0.4317077	-0.6012502	-1.930283	18	DDX6 PAFAH1B2 CBL PICALM FLI1 MAML2 SDHD	down	*
REACTOME_MITOTIC_PROMETAPHASE	0.0000011	0.0000424	0.6435518	0.4252564	1.929634	176	CEP72 BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TUBB2B CEP70 PLK1 NUF2 CDCA8 AURKB CENPA CCNB2 DYNC1I1 NCAPD2 ZWINT DCTN2 SPDL1 HAUS5 CEP250 KNTC1 BUB1 CENPL ODF2 SFI1 KIF2C MAD1L1 CDCA5 MAD2L1 CENPO SPC24 INCENP CDK1 CENPJ CENPH BIRC5 NCAPG KIF2A DYNLL2 CENPP FGFR1OP RANGAP1 MZT2A MZT2B CEP63 CEP192 TUBG1 NINL TUBB2A TUBA3D TUBA8 CENPQ NUP85 CENPK CKAP5 CDC20 CENPM TUBG2 CDK5RAP2 DYNC1LI2 CENPT HAUS6 HAUS4 CEP152 ALMS1 TUBGCP4 CEP164 TUBA4B ZWILCH SEC13 NME7 SMC2 CENPE TUBA1C PPP2R5D CLASP1 NCAPH CEP290 DYNC1H1 PLK4 AKAP9 PCNT DSN1 PPP2R5E TUBGCP2 NSL1	up	***
MCDOWELL_ACUTE_LUNG_INJURY_DN	0.0005510	0.0079579	0.4772708	-0.4766456	-1.929386	39	ACVRL1 CAV1 CDH13 CLEC10A ALAS1 EPB41L3 NFIX LTBP4 ABCG1 TP53BP2 SFTPB ICAM2 SFTPC BMP2K RSU1 C5 HEY1 SLC9A3R2 ADH1B TNFRSF19 DPP4 ANTXR1 FASN SCGB3A2	down	**
SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN	0.0001182	0.0022199	0.5384341	0.4794885	1.928060	69	CCNO BIK DEPTOR GALNT6 DNAJC12 TOX3 CLGN TSFM SPDEF TFF3 SLC27A2 AGR2 CA12 ASTN2 SLC4A8 TJP3 MCCC2 SIDT1 IKBKB TTC9	up	**
GO_CENTRIOLE	0.0000172	0.0004447	0.5756103	0.4500475	1.926967	111	SPICE1 MDM1 CEP89 MKS1 STIL PLK1 CCNF WDR90 CEP250 WDR62 CEP55 TSGA10 TOP2A FBF1 AURKA ODF2 SFI1 POC1A AGBL4 MPHOSPH9 CBY1 C2CD3 CCDC78 IQCB1 CROCC CENPJ KIAA0753 POC5 KIF2A POC1B FGFR1OP IFT52 CEP63 CEP192 TUBG1 CCDC151 CCDC146 CEP128 SASS6 AGBL2 WDR34 FTCD ODF2L NEURL4 CEP152 ALMS1 CEP164 NUBP2 KIF24 KIAA0586 CEP290 WRAP73 PLK4 FAM92B PCNT RILPL1 DZIP1	up	***
GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP	0.0000005	0.0000194	0.6749629	-0.3629385	-1.926785	174	ACP5 KMO USP12 SPN CAT RDX ARHGEF15 HSD17B11 SAMHD1 ST3GAL6 CORO1C CALCRL SLC39A8 PLEKHA1 SYS1 CD36 SLC44A2 MAN2B1 ARSB LIFR ABCG2 RNF125 CD93 SPI1 STAT5A DUSP3 DGKE PXDC1 KLF7 VIM TM6SF1 AKIRIN1 CNRIP1 TMEM9B S1PR4 ASNSD1 PSEN1 HECA STAT4 APBB2 PALM PI4K2B GMFG GYPC FAM43A ACSL1 YPEL2 EHD2 EPPK1 ALDH3B1 PPP2CB KCTD10 VPREB3 GALC ATXN1 COL15A1 STK40 ARPC2 ARHGAP18 GPD1L SCPEP1 FNIP2 MCOLN2 GPR171 LPAR6 BANK1 MAN1C1 CHP1 UBR2	down	***
GNF2_ICAM3	0.0010825	0.0135190	0.4550599	-0.5199191	-1.926396	29	HSD17B11 TXNIP DPEP2 EVI2B PTPRC SELL EMP3 GMFG ARRB2 ACAP2 ICAM3 DAZAP2 SH3BGRL3 IRF1 MYO1F APOBR TMEM127 HCLS1 ARHGAP25	down	*
WEST_ADRENOCORTICAL_TUMOR_MARKERS_UP	0.0003842	0.0059850	0.4984931	0.6434981	1.926040	21	PCSK6 KIF20A NEK2 ASPM PRC1 DTL TOP2A RRM2 CDK1	up	**
GO_RENAL_SYSTEM_VASCULATURE_DEVELOPMENT	0.0018525	0.0201623	0.4550599	-0.5400983	-1.926007	25	TEK PECAM1 FOXC2 GPR4 HES1 NOTCH1 CD34 PKD2 OSR1 EGR1 ANGPT2 CFLAR	down	*
WALLACE_PROSTATE_CANCER_RACE_UP	0.0000000	0.0000005	0.7614608	-0.3486047	-1.925958	258	RAMP3 CD52 DLC1 PECAM1 GPR65 THBD FYN SOX17 C5AR1 BCL2A1 GIMAP6 CD1C EOGT CD8A TMX4 DNASE1L3 WNT2B OLFML2A ANPEP RNASE1 MS4A1 SERPINB9 STOM CD93 TFEC SRGN CD37 GPM6A CNN1 FLI1 EVI2B TLE4 STK17B CLDN5 LY96 ITIH5 LAPTM5 COTL1 PTPRC SELL SELP CCL4 CD53 PRF1 FCER1G ALOX5AP PLEK EVI2A IL7R HLA-DQA1 MMP19 NCKAP1L PDK4 CREM CTSS CD48 C1QA RAC2 CCR7 GLIPR1 CD83 IRF8 GMFG GPR183 CELF2 IGKV3-20 RUNX3 ICAM2 NKG7 CD86 IRS2 GPR18 PLEKHO2 ETS2 IGKV1D-39 SYT11 TRAC SF1 CEBPD MS4A4A CXCR4 CTSC CD1E DOCK10 GPR171 SAMSN1 THEMIS2 IL16 LYZ CSF2RB PEX14 C1QB NR4A2 ITGAL MICAL1 CD69 GNG11 LAMP3 HLA-DRB1	down	***
GO_SISTER_CHROMATID_COHESION	0.0004333	0.0065469	0.4984931	0.5277669	1.925858	44	DDX11 DDX12P STAG3L2 BUB1B PLK1 ESPL1 STAG3 BOD1 BUB1 REC8 CDCA5 HORMAD1 DSCC1 FEN1 KIF22 ESCO2 STAG3L4 CDC20 CHTF8	up	**
GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP	0.0000004	0.0000153	0.6749629	-0.3688944	-1.925688	158	SIK1 OTUD1 LDB2 YPEL5 CCNL1 RBM7 HBEGF TM2D3 SDE2 BTG2 ZBTB21 NR4A1 MED26 NFE2L2 NDEL1 TIPARP CSRNP1 ITPRIP COQ10B ARNTL ATF3 BCLAF1 SMNDC1 ANXA3 RASGEF1B SIAH1 CREBRF ETF1 DCP1A GZF1 TMOD1 NECAP1 ETV3 PLK3 JUNB DHX15 GPR183 N4BP3 OSM REL SNRK FOS PTP4A1 PSMD12 PPTC7 CHORDC1 PHF3 SRSF4 SKIDA1 RGS2 PDE4B IST1 CCL20 JUND NR2E3 CXCR4 JMJD1C MAFK C20orf203 DNAJB9 CNTNAP3B ZNF326 PIM3 YTHDC1 ICOS EXOC8 ZFP36 CD69 LAMP3 TSC22D2 ZBTB46 MEF2D RAB1A NR4A3 JARID2 KBTBD2 SREK1 IVNS1ABP WHAMM SNX29P2 RELT FEM1C CYTIP KLHL29 PLCL1	down	***
GO_REGULATION_OF_INTEGRIN_MEDIATED_SIGNALING_PATHWAY	0.0017355	0.0191685	0.4550599	-0.6607479	-1.924776	13	LIMS2 EMP2 LIMS1 BST1	down	*
GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP	0.0000005	0.0000214	0.6594444	-0.3673935	-1.924686	163	ABHD5 SNX10 PTPRE TTC7B CD44 CTSW MYADM AQP9 SLC39A8 IL1RL1 GIMAP6 GNPTAB ZEB2 ANXA1 ATP2B1 CYP17A1 ARSB LATS2 ZDHHC2 LAIR1 IL18R1 PPT1 AHNAK PLEKHM3 CTSD ITGAX VIM ATP6V0D2 ID2 PRF1 DSTN IL7R PIK3R5 CALM2 EMP3 MYLIP HCST CCDC50 PTGER4 EEA1 DAPK2 COBLL1 TBX21 NKG7 KLRC2 XYLT1 PIK3AP1 SMPDL3B GSAP ATXN1 LGALS3 IL18RAP SEMA4A ARHGAP18 RIPK2 HAVCR2 KLRK1 RORA GIMAP4 CX3CR1 UBA6 ITGAL ITGB1 ARL4D S1PR5 ATP2B4 RPA2 DOCK5 GZMB MYO1F KLRC1 MYO5A TNFRSF1B F2RL2 SLAMF7 GZMK	down	***
GSE7852_LN_VS_FAT_TCONV_DN	0.0000003	0.0000113	0.6749629	-0.3619283	-1.924365	175	SEMA3G CXCL3 DENND5A SIK1 PLEKHF2 MYADM SRSF7 IL1RL1 BCL2A1 AGPAT4 ABCB1 ENTPD1 NR4A1 BTG3 TXN IL10 CFD DGKE CASP1 KLF9 STX3 SOCS2 SNIP1 TMBIM1 CDKN1A ATF3 HOPX PLEK PRKRA HCST KCTD12 SNHG8 UHRF2 PPP1R15A HSPA13 COBLL1 TBX21 DENND4A TAGLN2 HIVEP2 RUNX3 PKD2 FOSB NKG7 DCAF5 TSC22D1 ZCCHC10 DUSP5 SOD2 TOB1 ACYP2 RGS2 RXRA SPARCL1 CDC42EP3 CXCR4 FBXO30 HIGD1C S100A4 TTC19 SAMSN1 RORA IQGAP1 EHD4 ATF4 NR4A2 ITGB1 TRIM13 TSC22D2 ATP2B4 NFIL3 IMPACT AKAP13 METRNL NFKBIZ GZMB RNF19B MYO1F SLC25A28 PNP DENND4C KLRG1 EFEMP1 HSPA5 ZC2HC1A FARP1 FASLG TMEM64	down	***
GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0000005	0.0000217	0.6594444	0.4216063	1.923923	183	HMGA2 CEP72 TICRR NEK2 CCNB1 CENPF STOX1 BRCA1 CDK4 BRSK1 GTSE1 DBF4B KIF14 CEP70 PLK1 AURKB CDC6 TPX2 CDC25A ORC1 DTL ZFYVE19 CDK5RAP3 DCTN2 HAUS5 CEP250 HMMR SMARCD3 AURKA ODF2 SFI1 CLSPN CDC25C TOPBP1 CHEK1 PSMD4 BLM CDK1 CENPJ PSMB5 PSMC4 FGFR1OP CEP63 CEP192 TUBG1 NEK10 PSMA5 NINL PSME2 MTA3 FZR1 PSMD2 ATAD5 CDC7 CKAP5 PSMB3 CHMP4C WNT10B CDK5RAP2 UIMC1 HAUS6 HAUS4 PSMB4 CEP152 ALMS1 CEP164 PAXIP1 TP53 CDC25B CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT FBXO5 PSMB10 PSME1 NPM1 RCC2 NAE1 BRD4 TAOK2 CTC1 PSMD3 PPP2R1A RBX1 VPS4A PSMD8 DCTN3	up	***
GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN	0.0000013	0.0000479	0.6435518	0.4277452	1.923777	161	TRIP13 SLC16A14 COL24A1 GPT2 BUB1B CCNB1 PBK CCDC113 PHGDH GINS1 E2F8 STIL NUF2 IGKV4-1 PTTG1 CDC6 CCNB2 SPATS2 GLDC MYL6B CLPTM1L HMMR MKI67 BUB1 IGLV1-44 RRM2 KDELR2 CHEK1 PERP PHB EFCAB11 CDK1 NCAPG SPAG5 DLGAP5 IGLV6-57 GALK2 TIGD6 IGHM FKBP14 CEP128 DENND5B CDC20 CENPM EFHC1 FAM174A NT5DC2 SLC2A5 DCPS DOCK3 SHCBP1 RNF121 OSBPL10 GADD45GIP1 FAIM IGLV3-19 SRPRB ZBTB32 CBWD1	up	***
GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN	0.0000004	0.0000153	0.6749629	-0.3614443	-1.923660	177	DENND5A SIK1 ST3GAL6 S1PR1 MAL LAMP1 HEG1 TXNIP TOE1 ADA EIF1 BTG2 LITAF HNRNPDL CLK1 SRGN PDE4D CD37 MOAP1 SRSF5 SDCBP TPP1 LAPTM5 RBMS1 UBE2B PER1 RNF139 BCLAF1 AFF1 NCOA1 BTG1 RBM39 S1PR4 PPP2CA ELF1 SGK1 NXF1 PLK3 JUNB JAK1 DUSP8 WTAP DDX5 THUMPD1 HERC2P3 CLN3 SNRK CALM1 SRSF6 HBP1 HNRNPH3 FCGRT TOB1 RGS2 PDE4B RBL2 CCDC69 TPT1 CXCR4	down	***
GO_LEUKOCYTE_ACTIVATION_INVOLVED_IN_INFLAMMATORY_RESPONSE	0.0014052	0.0164487	0.4550599	-0.4880865	-1.923384	37	C5AR1 GRN CCL3 PTPRC IL6 C1QA JUN TYROBP IFNGR1 CST7 FPR2 SYT11 CTSC LDLR SPHK1 TREM2 TRPV1 IFNG JAK2 TLR3 ITGAM SNCA NAMPT ITGB2 NR1D1 IL33 MAPT MIR142	down	*
GO_FICOLIN_1_RICH_GRANULE_MEMBRANE	0.0006852	0.0094802	0.4772708	-0.4571290	-1.922936	46	CD55 LAMP1 SLC11A1 RHOA SIRPA CD93 CD58 GAA ITGAX FCER1G NCKAP1L PRCP ENPP4 SERPINB6 CR1 SIGLEC14 DOK3 FPR2 DYNC1LI1 ATP6V0C LGALS3	down	**
GO_POSITIVE_REGULATION_OF_BLOOD_VESSEL_ENDOTHELIAL_CELL_PROLIFERATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0035043	0.0329773	0.4317077	-0.6969769	-1.922631	11	HMOX1 GATA2 MIR27B MIR146A	down	*
REACTOME_HOMOLOGOUS_DNA_PAIRING_AND_STRAND_EXCHANGE	0.0003707	0.0058339	0.4984931	0.5418639	1.922518	40	BRCA1 RBBP8 XRCC2 EXO1 RHNO1 ATR TOPBP1 CHEK1 RAD51AP1 BRIP1 BLM DNA2 RAD9A RAD51D RAD50 PALB2 RPA1 RFC5 RAD51 RAD1 TOP3A ATRIP RMI1 RMI2 RAD51B RFC3 BARD1 RFC4	up	**
MIR6090	0.0038901	0.0355221	0.4317077	-0.7676573	-1.922336	8	ADCY9 DDX6 DSE ATL2 CDK14	down	*
GO_HELICASE_ACTIVITY	0.0000060	0.0001803	0.6105269	0.4352667	1.922336	138	DDX11 HELLS DDX12P RUVBL1 CDC45 POLQ TTF2 PIF1 GINS1 MCM4 MCM2 RAD54B MCM8 GINS4 RUVBL2 HLTF SMARCAL1 MCM7 HELB RAD54L MCM3 CHD6 DSCC1 BRIP1 BLM ERCC2 RECQL5 DDX56 DDX51 NAV2 DHX37 DNA2 DHX33 RECQL4 DHX34 MOV10 DHX40 CHTF18 GINS2 CHD5 RAD50 EP400 FANCM MCM6 CHTF8 DHX8 MCM5 DDX23 IGHMBP2 DDX55 SMARCA4 DDX54 RTEL1 RFC5 RAD51 SNRNP200 CHD3 SRCAP DDX52	up	***
GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY	0.0000243	0.0005894	0.5756103	0.4571032	1.921652	94	HMGA2 HELLS HJURP RUVBL1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A SMARCD3 SMARCC1 CHAF1A CENPL TPR CENPW CHAF1B CENPO ASF1B CENPH CENPP HIRA CENPQ NOC2L CENPK SUPT16H CENPV CENPM HMGA1 CENPT NFE2 SMARCC2 SUV39H2 SMARCA4 CHD3 SIRT6 TP53 SMARCB1 SART3	up	***
chr2p14	0.0030371	0.0293950	0.4317077	-0.5707398	-1.921286	20	PLEK CNRIP1 ACTR2 SERTAD2 RNU6-100P PNO1 MEIS1-AS2 PELI1 PPP3R1 MEIS1 AFTPH RAB1A CEP68	down	*
GO_POSITIVE_REGULATION_OF_PRI_MIRNA_TRANSCRIPTION_BY_RNA_POLYMERASE_II	0.0010972	0.0136666	0.4550599	-0.5303772	-1.921216	26	SMAD6 GATA2 BMP2 NR3C1 SPI1 IL10 TGFB2 SRF JUN FOS TGFB1	down	*
GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP	0.0000002	0.0000107	0.6749629	-0.3611907	-1.920634	176	SIDT2 MYO7B SGK3 PECAM1 PTP4A2 FYN VAMP2 MKNK1 ZBTB2 IL23A GINM1 ATP2B1 TACC1 EIF1 ACOT2 RNF125 CSGALNACT2 FOXP1 ADRB2 HNRNPDL CD93 IL10 ITPRIP MAFG KLF7 CEP57 CLK4 ELMSAN1 IL7R USP16 IKZF5 CDKN2AIP FAM102B NRROS GPBP1 MOB4 NXF1 NECAP1 ETS1 EPC1 SKIL UBAC2 RC3H1 TMEM167B REL SNRK CELF2 AZI2 SRSF6 ING3 BAZ2B CDC37L1 DUSP5 ADPGK SERINC3 TAGLN GEM PCM1 SF1 TOB2 CREBBP ULK2 CEPT1 SKI DAZAP2 PUM1 ZNF326 KALRN CDKN1B	down	***
GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_MIGRATION	0.0000249	0.0005981	0.5756103	-0.3975094	-1.920539	95	ANGPT4 SASH1 HMOX1 TEK GATA2 BMPR2 MIR27B ANXA1 MIR146A ADAM17 HSPB1 FOXP1 GATA3 NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 THBS1 PIK3C2A NUS1 ANXA3	down	***
ZHENG_FOXP3_TARGETS_IN_THYMUS_UP	0.0000002	0.0000097	0.6901325	-0.3589312	-1.920212	187	DENND5A LTA4H SAMHD1 CITED2 NR3C1 WBP4 ATP2B1 LATS2 RNF125 KLF6 ZYG11B PPP3CC FLI1 SDCBP DENND6A SOCS2 ELK3 ARL4A PPP2R5C IL7R FAM76B CNOT6L VCPKMT TBC1D5 ELF1 PHTF2 DCTN6 NEK7 ESD RAB8B PSMA1 LRCH1 STAT4 NSMCE2 ETS1 ARHGEF10 PIK3R1 UBAC2 GPR183 IDS PTGER2 MALT1 TPP2 NAA30 CELF2 GPRIN3 PELI1 CDK17 HIVEP2 ZFAND6 NUP153 ATP6V1A HBP1 ANKRD12 GPR18 PDE4B MBNL1 LDLRAD4 SESN1 SEC63 PIP4K2A CXCR4 SIK3 ZBTB25 JMJD1C DOCK10 B3GNT2 C21orf91 EVI5 FAM8A1 CD69 SLC25A40 MAN1A1 MAP3K1 TRAT1 ITGA6 DUSP22 JARID2 IRF4 AKAP13 TTC39B NFKBIZ	down	***
GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN	0.0000003	0.0000124	0.6749629	-0.3610899	-1.919907	175	IL1A CXCL16 SNX10 INSIG1 TBC1D7 ZCCHC2 CIR1 BCL2A1 SCARF1 RCHY1 PILRA FGR ZEB2 RRAGC CARD16 MCTP1 SLC7A7 ADAM17 MTF1 RNF144B TFRC EIF1B STAT5A MAFG NPR3 ATG7 NFKB1 PNRC1 PRF1 CCDC59 INHBA PIK3R5 PROCR LACC1 ELF1 MAML2 SERPINB8 PSMA1 ARL5B SH3BP5 CPEB4 HRH1 MAP4K4 OSTM1 WTAP PNPLA8 PTGER2 CXCL5 ADNP2 PIK3AP1 DUSP5 SOD2 ETS2 ZNF438 IER5 MS4A4A HSP90AA1 TAB2 RBM18 G3BP2 HNRNPC CEPT1 LINC00884 SLFN11 SPHK1 RABGEF1 SLC16A10 MB21D2	down	***
GO_CENTROMERE_COMPLEX_ASSEMBLY	0.0003151	0.0050878	0.4984931	0.5579574	1.919630	34	HELLS HJURP RUVBL1 CENPF CENPA MIS18A CENPL CENPW CENPO CENPH TRAPPC12 CENPP CENPQ CENPK CENPV CENPM CENPT	up	**
GO_DOUBLE_STRAND_BREAK_REPAIR_VIA_BREAK_INDUCED_REPLICATION	0.0003733	0.0058495	0.4984931	0.7647256	1.919407	11	CDC45 MCM4 MCM2 GINS4 MCM7 MCM3 GINS2 CDC7 MCM6 MCM5	up	**
GO_ENTRAINMENT_OF_CIRCADIAN_CLOCK_BY_PHOTOPERIOD	0.0035787	0.0334785	0.4317077	-0.5770472	-1.919344	19	SIK1 CRY2 RBM4 PER3 USP2 FBXL3 PER2 ID2 PER1	down	*
GO_POSITIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS	0.0018073	0.0197812	0.4550599	-0.6588619	-1.919282	13	MAL SFRP1 THBS1 ATF3 SKIL PEA15 STK4 TIMP3 PTEN PMAIP1	down	*
NUYTTEN_EZH2_TARGETS_DN	0.0000000	0.0000000	1.1601796	0.3769613	1.918290	884	CPS1 RIBC2 SLC16A14 PTGES FOXM1 SLC16A9 KIF20A HJURP CDC45 TICRR DNAH2 PARPBP MCM10 FANCI TROAP NEK2 CCNB1 CENPF TIMELESS FLVCR1 UBE2T PAGR1 GBAP1 PDCD2L PSPH DNAJC22 MND1 PBK KIF18B TTF2 NDC80 DEPDC1 BRCA1 PHGDH DEPDC1B CDCA7 C12orf66 CREB3L4 TTK MUC5AC RACGAP1 IQGAP3 E2F8 GTSE1 SLC27A2 KIF14 L3MBTL1 CCDC14 TRAIP NIPSNAP1 ASPM STIL SAYSD1 PLK1 NUF2 IFT27 CDCA8 AURKB CENPA PTTG1 ALDH18A1 ECT2 PAK6 TPX2 CCNB2 UHRF1 MCM4 MCM2 RAD54B TYMS SP5 CDC25A UMPS COCH PRC1 ANKRD36B DTL TDRKH MCM8 MIS18A MAP2K6 GINS4 NCAPD2 ZWINT MRPS35 CDT1 CCT2 LSM5 MAGEF1 HAUS5 MANSC1 C5orf34 NR2C2AP TMEM41A HMMR EXO1 NUDT1 MAP7 NLE1 KIF23 CEP55 CHAF1A SYTL2 RPL39L RPAP1 F2RL1 EMC9 KIF15 TRIM29 KNTC1 BUB1 FANCA TOP2A CENPL PUS7 AURKA NUP155 REC8 P4HTM ODF2 SAE1 GTPBP3 LARS2 KIF2C MCM7 E2F2 CENPW POC1A CLSPN ABCC5 RRM2 WIPI2 MMS22L CDCA5 WDHD1 SGPL1 HOOK1 RAD54L EIF2AK1 FANCD2 TRPT1 LMNB1 CDC25C PPP1R35 BRI3BP SIDT1 TOPBP1 SPINT1 THYN1 CKAP2L NFYA FBL RAB13 RAD51AP1 EHHADH XRCC1 PIH1D1 THAP10 KHK SPC24 DSCC1 CAD RAD18 INPP4B BLM CCDC136 COMMD4 NOL3 ZNF587 SLC45A3 CCDC138 PSRC1 GEMIN4 THOP1 CASP6 CKS1B EFCAB11 PRRT3 CMAS CDK1 CEP97 EXOSC2 CENPJ DIDO1 BCAS4 RFWD3 CENPH BIRC5 ATP6V0E2-AS1 ABHD17C CCM2 C1orf112 WDR54 GMNN DNA2 MKRN1 PACSIN1 DHX33 LARP1 NEIL3 SSX2IP EZH2 DYNLL2 SPAG5 RAB11FIP4 ETFB MTBP RECQL4 FGFR1OP RNASEH2A RNF44 MYO19 FANCG IFI27L2 UBFD1 CRLF1 CCNE1 GNPAT DLGAP5 SCLY ARHGEF16 SPG7 SLC26A2 GALK2 CTSV TACC3 KIF22 MRPL11 USB1 TRIM37 SSRP1 ZNF544 DTYMK C1orf131 CHTF18 CENPQ JMJD4 ESCO2 GINS2 SPAG1 KIF20B SPA17 LRRC20 BCL2L12 POLD1 MAGOHB TMEM30B CDC7 SLX4IP ETV4 SASS6 GEMIN6 KLHDC3 EFCAB7 BRD8 CDC20 ORMDL2 CENPM WDR34 EFHC1 GPATCH4 CDR2 CDK5RAP2 MRPL24 ASRGL1 HOXA3 MRPS33 PRMT1 ANKRA2 HEATR1 C1orf56 HAUS6 RABEPK ADD3 OVOL2 HAUS4 PSMB4 NT5DC2 ATAD2 TCERG1 COPZ1 PATZ1 EPCAM DPH5 DDAH1 SPON2 SH3D21 CATSPER1 GLIS3 CCNA2 PRIM1 DZIP3 PRR11 TIGD2 BANF1 SHCBP1 TMEM141 RFC5 SYBU WDR4 ELOVL4 HOOK2 LPGAT1 RAD51 NBR1 MTIF3 ZWILCH CDK5 AGBL5 WDR76 SLC12A2 ARHGEF39 TARBP2 TONSL CPT1C GMPR2 TMEM260 CENPE RPP25L POP4 SWI5 CMTM8	up	***
GO_NEUTROPHIL_APOPTOTIC_PROCESS	0.0040265	0.0363795	0.4070179	-0.7659733	-1.918119	8	HCAR2 ANXA1 SLC7A11 IL6	down	*
TIAN_TNF_SIGNALING_NOT_VIA_NFKB	0.0030881	0.0298249	0.4317077	-0.5697651	-1.918005	20	GATA2 INSIG1 KLF10 KLF6 NR4A1 TIPARP TPTEP1 JUN JUNB PPP1R15A FOSB PDE8B EGR1	down	*
GO_HEMIDESMOSOME_ASSEMBLY	0.0007015	0.0096530	0.4772708	0.7793763	1.917382	10	COL17A1 KRT5 LAMC2 ITGB4	up	**
GNF2_MLH1	0.0003741	0.0058549	0.4984931	0.5523487	1.917042	36	FANCI NUP107 NDC80 CCT2 KNTC1 CCT5 CBX3 MCM3 SNRPE PA2G4 ILF2 SSRP1 SUPT16H SNRPD1 SRSF1 TCERG1 MSH2	up	**
GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN	0.0000057	0.0001730	0.6105269	0.4425407	1.916667	121	TFPI2 SLC16A14 NDC80 DEPDC1 TTK ANLN ECT2 CDC6 GAPDH FIGNL1 MCM4 BCL2L14 MCM8 NME1 RANBP1 HMMR EXO1 C9orf116 POLA2 MSX1 ICA1 SMYD2 RAD54L KIF11 C7orf50 KCNJ11 BLM TSHR PLA2R1 GEMIN4 EFCAB11 TNFRSF21 POLR3K REEP6 EIF6 DENND6B HMGN3 TRIM37 ESCO2 SYT1 CABLES2 LRRC59 MCM5 NMNAT1 TMEM198 ALG8 ESRRB SHCBP1 ACSF3 COX5B FAM118B MRPS27 COPZ2 MRPL20 ERRFI1 SLC1A7 NQO1	up	***
SMIRNOV_RESPONSE_TO_IR_2HR_UP	0.0005138	0.0075185	0.4772708	-0.4558779	-1.916325	47	RAB11FIP1 FOSL1 PPM1D SLC7A11 CLK1 CCL3 CDKN1A ATF3 ID2 HCAR3 SGK1 JUN PPP1R15A PTGER4 CD83 NUDT15 TNFRSF10B C16orf72 PIM1 SESN1 IER5 TNFSF9 NUP160 PMAIP1	down	**
GO_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY	0.0003293	0.0052644	0.4984931	-0.4557082	-1.915946	49	SASH1 SCIMP CD55 IL1B LY86 TRIB1 CD36 CARD16 TRAF6 PTAFR LY96 CCL3 IRAK2 TLR4 HCK CARD8 PRKCE MALT1 TGFB1 CD6 IL18 RIPK2 NFKBIA	down	**
GSE7852_THYMUS_VS_FAT_TREG_DN	0.0000010	0.0000362	0.6594444	-0.3640856	-1.915741	168	MIR22HG INSIG1 STX11 TSHZ1 ABCB1 GINM1 ARSB ASAH1 GM2A ZDHHC2 ZNF503 FZD4 ADRB2 NDEL1 CYP4V2 TIPARP RHOB KDSR ARRB1 DUSP3 SORBS1 UHRF1BP1L DRAM1 CDKN1A NR1D2 PER1 ELMSAN1 GNAQ MAFF HGSNAT RBPJ ELF1 FAM189A2 WSCD2 IFNGR1 ENPP4 NPR1 FAM177A1 DENND4A SNX9 YPEL2 PKD2 PRKCG CCR4 IRF5 APBB1 PHF19 BMP2K IL18RAP YAF2 CEP170 ITPRIPL2 ARL14EP S100A4 EPB41L4A TNFSF9 SAMSN1 RORA MT2A ATF4 TRIM36 CBX7 PIM3 HERPUD1 JDP2	down	***
GO_G2_DNA_DAMAGE_CHECKPOINT	0.0004652	0.0069429	0.4984931	0.6235385	1.915336	23	HMGA2 BRCA1 BRSK1 PLK1 DTL CDK5RAP3 CLSPN CHEK1 BLM CDK1 FZR1 UIMC1	up	**
REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	0.0011473	0.0141472	0.4550599	-0.5117263	-1.914490	31	CLEC1B FYN CDC42 RHOA RHOB FCER1G PIK3R5 RAC2 RHOG PIK3R1 PLCG2 VAV3 LAT	down	*
REACTOME_CELL_CYCLE_MITOTIC	0.0000000	0.0000000	0.8870750	0.3889002	1.913743	455	FOXM1 CEP72 KIF20A CDC45 MCM10 BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 PRIM2 TUBB2B GINS1 CDK4 GTSE1 POLE CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 E2F3 TFDP2 CCNB2 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 ORC1 DYNC1I1 MCM8 GINS4 NCAPD2 ZWINT CDT1 DCTN2 SPDL1 HAUS5 CEP250 HMMR BTRC KIF23 KNTC1 BUB1 TOP2A CENPL AURKA NUP155 ODF2 POLA2 POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 E2F2 RRM2 LPIN3 CDCA5 MCM3 LMNB1 CDC25C LIG1 ORC6 MAD2L1 PSMD4 CENPO SPC24 AKT2 PKMYT1 MNAT1 SKP2 INCENP CKS1B NCAPG2 CDKN2C ANAPC5 CDK1 POLE2 CENPJ CENPH BIRC5 GMNN E2F1 NCAPG PSMB5 DNA2 KIF2A ANAPC7 FEN1 NUP205 DYNLL2 PSMC4 CENPP FGFR1OP KPNB1 RANGAP1 MZT2A MZT2B CEP63 CCNE1 CEP192 CDC23 TUBG1 PSMA5 NINL TUBB2A PSME2 TUBA3D TK1 TUBA8 CENPQ HDAC1 ESCO2 GINS2 FZR1 LIN37 ANAPC1 POLD1 PSMD2 NUP85 PPME1 CDC7 CENPK CKAP5 PSMB3 CDC20 CENPM TUBG2 AAAS RPA1 CHMP4C CDK5RAP2 MCM6 DYNC1LI2 CENPT MCM5 HAUS6 GINS3 RCC1 HAUS4 PSMB4 CEP152 NUP62 ALMS1 CCNA2 PRIM1 BANF1 ANAPC2 RFC5 TUBGCP4 CEP164 LPIN1 TUBA4B ZWILCH SEC13 FBXW11 NME7 CHMP2A SMC2 MAU2 CENPE TP53 GOLGA2 LEMD2 CDC25B UBE2C NCAPD3 TUBA1C PPP2R5D NUP210 CLASP1 NUP93 FBXL18 NCAPH CEP290 CHMP6 DYNC1H1 PLK4 AKAP9 PCNT DSN1 CDK11B RBL1 PPP2R5E FBXO5 PSMB10 LCMT1 TUBGCP2 PSME1 NSL1 TMPO	up	***
GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_UP	0.0000004	0.0000181	0.6749629	-0.3633532	-1.913237	170	ACP5 PDLIM2 LRRC8C LIPA FCER1A FLVCR2 CYB5R3 TET2 TGFBR2 SPCS3 PLA2G7 STARD4 LATS2 HSPB1 HLX ZMYM6 TXN TAPT1 AHNAK LIMS1 SLC46A2 TMED5 MGAT4A ID2 DSTN CALM2 DEGS1 CMTM6 FAM102B RBPJ RYBP PHTF2 UTRN CYB5R1 C20orf194 TYROBP HSPA13 FRYL ZBTB24 ENTPD4 FAM177A1 RNF24 SLC25A24 BTBD6 CALM1 ZFAND6 LGALS3 RGS2 ZNF267 RAB5A PIP4K2A DAPK1 TLR10 DOCK10 DAZAP2 TRIM36 CYBA CSF2RB C1QB CTSH CAPZB CLOCK ZYX EXOC8 KMT2E ATP1B1 CALR MICAL1 RGS12 GLIS2 ZFYVE21 CCNYL1 NTAN1	down	***
GO_BMP_RECEPTOR_ACTIVITY	0.0006868	0.0094976	0.4772708	-0.8959766	-1.912878	5	ACVRL1 SOSTDC1 BMPR2	down	**
GO_CALCITONIN_FAMILY_RECEPTOR_COMPLEX	0.0001286	0.0023829	0.5188481	-0.9648766	-1.912762	4	RAMP3 RAMP2 CALCRL	down	**
GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN	0.0000006	0.0000259	0.6594444	-0.3602893	-1.912721	174	SASH1 TAL1 HHEX GLIPR2 LPXN GPR65 SIK1 OTUD1 HEATR5B MYD88 S1PR1 HSPE1 NFIX RNF144B ABCG1 BFAR SPRY2 PPP1R13B CWC22 ITPRIP CASP1 SLC7A8 ARNTL SOCS2 ITPK1 PDE8A MGAT4A CDKN1A AXL RSL24D1 SNN TDRD7 HCK USP25 ARHGAP17 MCMBP PLEKHA3 NECAP1 ETV3 OSM MORC3 FOS PELI1 CD164 AZI2 RIN2 TCF4 AP1G1 KHDRBS1 GNB4 UTP3 KAT2B TSPO IL18 XKR8 PUS10 G3BP2 FNBP4 CYTH1 TMCC3 FEZ2 DNAJA2 SPATA13 HAT1 PHYH ZNF800 ENDOD1 PLEKHA2 SNW1 PPIP5K2 XRN2	down	***
KOINUMA_COLON_CANCER_MSI_UP	0.0008875	0.0116078	0.4772708	0.6984298	1.912672	15	TYMS CXCL10 TPBG HOXC6 CXCL9 NCAPG PSMB5 ANP32E	up	*
KEGG_BASE_EXCISION_REPAIR	0.0005966	0.0085049	0.4772708	0.5714806	1.912487	32	POLE LIG3 SMUG1 POLD2 LIG1 XRCC1 PARP1 POLE2 UNG NEIL3 FEN1 POLL MBD4 POLD1 POLB MPG NEIL1 APEX1 PARP2	up	**
AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP	0.0000000	0.0000009	0.7477397	0.4045139	1.912345	268	CEP72 SLC26A4 EPN3 PDCD6 TTF2 BET1 LHB UBE2Z SNF8 NDUFS6 EXOC3 COX11 PVT1 INTS1 CYP3A5 NME1 MICALL2 RUVBL2 OSBPL2 SDHA PON3 AP4M1 GPER1 WDR3 IRF3 MAD1L1 TRRAP WDHD1 ZNF146 LIG1 BRD9 SARS2 ZNHIT1 ACSF2 LRRC37A4P SPAG8 PHB CNOT3 PON2 CMAS NSF KCTD7 ZNF652 ARPC1A VPS28 GIPR ZNF419 SNAPC1 TMEM8B PRPF6 SLC25A13 TAF6 MRPS12 CBX1 UCKL1 DDT ZNF623 ZKSCAN5 KPNB1 TPD52L2 G6PC3 ZGPAT ARFRP1 DLGAP5 COA3 AARSD1 XYLT2 PLEKHG3 LMTK2 CLTA ASNS EPN1 STRN4 TSTA3 LRRC59 ACLY PPP1R3D GID8 PRMT1 NOSIP SNX11 SLC1A5 PRKD2 WDYHV1 EIF3K U2AF2 NUP62 ZNF580 AP2S1 PMS2P1 RCN3 SNRPD2 PAK4 NBR1 ARHGAP5 RSAD1 SNRNP70 ZNF573 NUBPL NMT1 FIS1 FBXO34 TAF4 RASA4 NPR2 PPP2R5D SPATA20 SS18L1 PCTP CYHR1 LUC7L3 PPP1R13L PDK2 UTP18 LPCAT1 PNPO LAMA5 ASL TCFL5 PARP4 NDRG1 PLOD3 CRCP SLC12A9 CABYR BECN1 PSMD8 EEF1D RGP1 ZNF460 HIF1A SNX6 GYS1 MRPL13 MPP2 PLEKHA4 TUG1 ZC3H3 ARL17A GRWD1	up	***
GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP	0.0000021	0.0000718	0.6272567	0.4272423	1.912027	156	KIF20A CDC45 DEPTOR TROAP NEK2 UCHL1 TG KIF18B IGFBP6 AURKB LAMP5 PTTG1 TPX2 CCNB2 TYMS GLDC CDT1 MELK EXO1 MKI67 EMC9 TRIM29 TOP2A APOL1 E2F2 RRM2 RAD54L SEC61A1 KDELR2 IGKV1-5 ASS1 SCAMP5 COMMD4 WNT5B PSRC1 CDK1 NCAPG COL3A1 SPAG5 IGLV6-57 LMF1 TK1 DTYMK GINS2 IFNAR2 NOC2L MAT1A KDELR3 CDC20 DYNC1LI2 XRCC4 SSH3 HAX1 GINS3 DOLPP1 PDIA4 NT5DC2 CEACAM5 CEP85 B9D1 CCNA2 HDLBP ARSA GTF3C5 WDR76 IGLV3-19 UBE2C DHRS9 CALU CD38 BCKDK	up	***
GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP	0.0000007	0.0000272	0.6594444	0.4205714	1.912019	179	HP KIF20A CDC45 MCM10 NEK2 UBE2T BRCA1 TTK IQGAP3 E2F8 ANLN ASPM CDCA8 AURKB CENPA ECT2 CDC6 CCNB2 TYMS PRC1 CCNF DTL SPDL1 CISD1 SMARCC1 KIF23 CHAF1A MKI67 BUB1 TOP2A AURKA KIF2C RRM2 KIF11 LMNB1 CDC25C LIG1 CHEK1 MAD2L1 RAD51AP1 PERP INCENP CKS1B CDKN2C NUSAP1 ASF1B CDK1 POLE2 UCK2 BIRC5 GMNN SUN1 DNA2 EZH2 CBX1 IFI27L2 DLGAP5 PSMA5 TACC3 KIF22 TK1 GALNT3 RHD DHRS1 CKAP5 CDC20	up	***
GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP	0.0000009	0.0000353	0.6594444	-0.3597602	-1.909547	180	CXCL3 KMO SC5D CLIC3 IL1A STAC SLC12A6 OLR1 IL1B FBP1 LPL RASAL2 CORO1C ALAS1 BCL2A1 NCF2 IL1RN IGSF6 FGR HEG1 ASAP1 TNIP3 RGCC BTG3 TXN ATP6V1H TMEM38B TUBB6 EPB41L2 PTPN12 CCL22 ADO PTAFR PLAUR CLIC4 RIT1 VIM CCL4 ALOX5AP INHBA MAFF CRIM1 CD80 IL6 IL2RB PPA2 JUN MAP4K4 CYCS	down	***
GERY_CEBP_TARGETS	0.0000246	0.0005943	0.5756103	-0.3837413	-1.909476	108	EREG HMOX1 ABHD5 PPARG MNDA GREM2 LPL BAIAP2 GPCPD1 HMGCR IER2 HBEGF BTG2 PTX3 SERPINB9 TFRC KLF4 PLAUR ID3 PER2 CXCL2 ATF3 ID2 DUSP1 NUS1 HGSNAT PROCR TCTE3 CYB5R1 HSPA1B JUNB PPP1R15A IFRD1 ACSL1 FOS CHORDC1 PEA15 CD1D PIM1 RGS2	down	***
PER1_TARGET_GENES	0.0020959	0.0222363	0.4317077	-0.5354569	-1.909455	25	SNORD12 SNORD12B SNORA81 RABGGTB RPL17 RBM39 SGK1 RPL21 HNRNPK SFPQ EIF4A2 HNRNPH1 SNRPG GAS5 SLC38A2 PNRC2 SNORA63	down	*
GSE3982_CTRL_VS_LPS_4H_MAC_DN	0.0000004	0.0000156	0.6749629	-0.3590974	-1.909313	175	KMO SASH1 DENND5A USP12 CD55 LYVE1 BACH1 DDX6 CAV1 MYD88 ARL8B IL1RN IL23A CYB5A HIPK3 KLF6 NDEL1 BTG3 TUBB6 TIPARP EIF1B ROCK2 TBC1D9 BIRC2 CLIC4 ERP44 CCSER2 PLEK PIK3R5 MAFF TDRD7 HCAR3 DCP1A CD80 SAR1A NEK7 OASL CD48 MTMR9 RCAN1 IRF8 CREB1 ATP13A3 REL HIVEP2 RUNX3 MME CCR4 TFEB EWSR1 KCNA3 PDE4B PITPNA ABL2 NBN CEBPD LRP12 SP100 TRAF1 HNRNPC FAM13C SFPQ RAB2A PMAIP1 LYZ SPHK1 IRF2 SPSB1	down	***
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_DN	0.0003632	0.0057379	0.4984931	-0.4539811	-1.908685	49	CD1C GGA2 ENTPD1 GM2A BTG2 HDC ROCK2 STK17B PTGER3 UTRN RNF24 CPA3 MAP3K2 RGS2 KAT2B CCR6 LDLRAD4 ICAM3 CD1E PDE4A GPR171 HNRNPH1 NR4A2 IRF4 CYP1B1 IVNS1ABP PLXNC1 PTPN22 FGL2 HIP1 CASP8 UGCG	down	**
GO_REGULATION_OF_MODIFICATION_OF_SYNAPTIC_STRUCTURE	0.0036245	0.0337591	0.4317077	-0.7179135	-1.908622	10	BAIAP2 CDC42 RHOA CTTNBP2 TIAM1 EPHA4	down	*
MIR92A_1_5P	0.0005197	0.0075920	0.4772708	0.5419297	1.908053	38	FBXO27 WFDC2 SLC2A1 SIX4 FCGR3B PRKCA ACY1 TNC LMLN ODF2 CXCL9 COL1A1 MSI2 S100A9 CEP128 PPME1 SH3TC2 AKAP6 HDLBP BBX MLLT6	up	**
GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN	0.0000004	0.0000174	0.6749629	0.4167085	1.907783	187	TRIP13 PARPBP GMDS BUB1B DOC2A CCDC34 PBK GINS1 E2F8 PLK1 CDCA8 AURKB E2F3 CCNB2 FIGNL1 UHRF1 MCM4 TYMS PRC1 ORC1 DTL RANBP1 MELK EXO1 NUDT1 KNTC1 CDCA5 WDHD1 RAD54L LMNB1 CHEK1 ORC6 MAD2L1 GNPDA1 PPIL1 INCENP CKS1B CXCL14 RFWD3 NPM3 SLC25A13 SDCBP2 PSAT1 NEIL3 FEN1 DYNLL2 CCNE1 PSMA5 ALDH7A1 KIF22 COL5A2 TRIM37 TK1 CASP7 MLEC GINS2 SAP30 MAGOHB HLA-A CDC7 CLDN12 CDC20 FAF1 ASRGL1 DYNC1LI2 PRMT1 CKAP2 MCM5 RCC1 RAB34 CCNA2 PRIM1 RFC5 HK2 RAD51 ZWILCH SEC13 ARHGAP11A	up	***
TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C	0.0000000	0.0000000	0.8390889	0.3917117	1.907671	389	TRIP13 SLC16A14 FOXM1 CEP72 HELLS FAM81A TICRR PARPBP ZNF273 ZMYND8 BUB1B PPIP5K1 NEK2 UGT8 CCNB1 CENPF CPSF6 CMTM1 RAB3IP PHGDH CDCA7 CDCA2 CDK4 PRR15L GTSE1 DBF4B KIF14 POLE STIL PLK1 AURKB CENPA FIGNL1 CDC25A MYBL2 XRCC2 CCNF DTL MCM8 MARVELD3 XPO5 MIS18A ZNF107 TTLL4 MELK SPDYE3 MKI67 KIF15 AURKA KIF2C CLSPN MPHOSPH9 RRM2 MMS22L HOOK1 RAD54L KLHDC4 KIF11 PASK FANCD2 GPSM2 MCM3 LMNB1 PFN2 LIG1 BRI3BP CC2D1A CKAP2L CENPO LRRC37A4P SPC24 PKMYT1 BRIP1 GNPDA1 DPY19L1P1 SKP2 PSRC1 PTPN3 NUSAP1 ASF1B TNFRSF21 CENPJ DIDO1 UNG L2HGDH DNA2 ANAPC7 FEN1 LRRC37A2 ZNF623 PRR22 PA2G4 KPNB1 NRGN MZT2B DCLRE1C FOXRED1 MNS1 ARHGAP32 RAD51D COPS7B ZNF544 ENAH PDRG1 ITFG2 KIF20B TSEN54 ESR1 DENND5B ATAD5 GOLM1 KLHL23 ZNF202 SH3GLB2 HAUS6 RAB3D GINS3 PIGX HAUS4 CEP152 STRBP CEP85 ALMS1 LRP11 CCNA2 CANT1 DENR SHCBP1 NAV1 PCBD2 CCDC9 RAD51 PPP6R2 MCU ARHGAP11A OXCT1 ZNF700 ZMYND19 MLLT1 SNRNP70 POMK ZNF91 CENPE SMPD4 ESPN SYNE2 ZNF681 FUT10 ADCK2 NUP210 DNM1L C4orf46 MTG2 PRKAG1 ERLIN1 XPO6 FGFBP3 MORN4 MED22 MIOS SHQ1 PLK4 PPARGC1B PRPF19 LPCAT1 ABHD2 TNPO3 KRIT1 TOMM40 SNHG17	up	***
GSE3039_CD4_TCELL_VS_B1_BCELL_DN	0.0000007	0.0000290	0.6594444	-0.3640454	-1.907146	163	SIRPB1 SLPI SLC31A2 MCOLN1 GLIPR2 IL1B CD44 KCNN3 CD9 IL1RN LAMP1 SLC11A1 RHOA TXNIP CD33 CLEC7A ANXA5 ADIPOR1 ADRB1 STOM SIRPA CD93 MCL1 TMEM38B FOXC2 SDCBP MEFV MPEG1 BST1 ITM2B USP2 FAM49B CTSD CCL4 CD302 CD53 FCER1G CD300C HTRA4 BTG1 CABLES1 HPGDS TYROBP STX7 LPCAT2 CAP1 ZBED5 MCAM PIK3AP1 TIMP2 ATP6V0C CNTNAP1 SOD2 CCR1 MR1 TCTEX1D4 TNFAIP8 GSTM5	down	***
GSE12366_GC_VS_MEMORY_BCELL_DN	0.0000010	0.0000373	0.6435518	-0.3592753	-1.906973	180	CLIC3 SLC12A6 CD55 RDX GPR65 BACH1 PLEKHA1 LAMP1 IL23A SPCS3 TXNIP MAN2B1 ASAH1 ENTPD1 NAAA PARVG JAM3 KPNA5 RHOB ZMIZ1 DGKE PTPRO ITM2B ZADH2 ITPK1 CDKN1A CCND2 DUSP1 N4BP2L1 SNN SERTAD2 S1PR4 CD48 LIMD1 IFNGR1 CCR7 GPR183 SERPINB6 TSPYL1 KLF2 FOSB CR1 RPL21 ATXN1 ADPGK MACF1 N4BP2L2 PLEKHO2 POLK PDE4B CCR6 MOB3B SESN1 IER5 ISCU DOCK10 SKI LTBP3 NABP1 EIF4A2 BMI1 PHYH PLAG1 CRTAP CLIP1 TGOLN2 ITGB1 RAB37 DRAM2 NDFIP1 CSNK1G3 TES FNDC3A STARD5 MAP3K1 KLHDC1 ATF6 DUSP22 CFLAR FAM89B MYO1F	down	***
PID_AURORA_B_PATHWAY	0.0004138	0.0063222	0.4984931	0.5494427	1.906956	36	KIF20A NDC80 RACGAP1 CDCA8 AURKB CENPA NCAPD2 KIF23 BUB1 AURKA KIF2C NSUN2 INCENP CBX5 BIRC5 NCAPG	up	**
OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP	0.0000001	0.0000059	0.6901325	-0.3559055	-1.906637	192	RAB11FIP1 CXCL3 EREG IL1A IL1B CD44 PAFAH1B2 BCL2A1 IL1RN TRIB1 IER2 ABCG2 BTG2 KLF6 RNASE1 PTX3 HNRNPDL SPRY2 MCL1 TIPARP KLF4 KLF9 DAB2 CCL3 CDKN1A CXCL2 ATF3 CCL4 DUSP1 ARL4A CA1 MAFF ADD1 TBC1D5 HCAR3 AREG IL6 SGK1 IL2RB SLCO2B1 SF3B1 JUN TREM1 JUNB PPP1R15A PTGER4 FERMT2 BAG5 FBXO11 CD83 GPR183 ATL2 DLEU2 FOS ADNP2 RHOQ KLF2 FOSB FLNC EPB42 EHD1 TCF4 COL15A1 SOD2 SBSPON RGS2 PDE4B ETS2 ICAM1 IER5 CDC42EP3 SIK3 CCR9 PSME4 NFKBIA NUP160 SPSB1 EGR1 NR4A2 HIPK1 SSB FUS ZFP36 YRDC	down	***
GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_UP	0.0000007	0.0000268	0.6594444	-0.3591169	-1.906497	174	MIR22HG LYL1 EGR2 PDE1B PLEKHF2 RCHY1 IER2 PDE2A STARD4 B3GNT5 EMILIN2 TMEM74B LITAF KLF10 TIPARP MAP2K3 FABP5 GAA USP2 MYO1B PLBD1 SPAG9 LAPTM5 LBH M6PR CD53 PER1 PLEK ELMSAN1 SH2D2A IL7R RPS6KA2 RBPJ MYO1C CABLES1 HIC1 FOXN2 PTGER4 KLHL18 GPR183 MALT1 REL RGS13 CST7 TPRA1 ATP6V0D1 FOSB CD74 TGFB1 PEA15 VPREB3 TSC22D1 NAB1 CD86 IRS2 RGS2 CCR6 LAT TOB2 UBE2D1 MMD FNBP1 CBX7 CYBA ATP6V0A1 EGR1	down	***
PID_ATM_PATHWAY	0.0005004	0.0073562	0.4772708	0.5869763	1.906411	28	CHEK2 BRCA1 RBBP8 CDC25A TP53BP1 FANCD2 CDC25C MDM2 BLM DCLRE1C RAD9A RAD50 XRCC4 UIMC1	up	**
GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP	0.0000022	0.0000762	0.6272567	0.4194331	1.906348	178	KIF20A FANCI BUB1B PBK TTF2 TBRG4 TOMM34 CENPA ESPL1 CCNB2 TYMS PRC1 SRPK1 ZWINT CDT1 NLE1 PON3 KIF15 KIF3B TOP2A PUS7 WDR3 TTLL12 CAD INPP4B MNAT1 SKP2 TMEM106C CDK1 POLE2 CEP97 UCK2 MCAT EZH2 POLR1C FGFR1OP KPNB1 EIF6 SNRNP25 MRPS34 LONP1 OSBPL3 TK1 DTYMK ANAPC1 MAGOHB MARCKSL1 YARS2 SUPT16H TIMM13 TSTA3 CENPM MYO5C STAMBP CKAP2 GINS3 STK39 SHCBP1 WDR77 RAD51 MRPL9 SMC2 DDX52 MTHFD1 PAICS UBE2C NCAPD3 TUBA1C PPP1R14B COX17 BRIX1 FBXL18 ERCC3 NCAPH F5 EIF2D AVEN POLRMT MRTO4 C12orf43 PTPRK MRPL12 CLPP HINT1	up	***
GO_RESPONSE_TO_CGMP	0.0007393	0.0100437	0.4772708	-0.8926946	-1.905871	5	SLC6A4 RAPGEF2 PDE2A	down	*
GO_CENTRIOLE_ASSEMBLY	0.0006531	0.0091441	0.4772708	0.5611338	1.905690	33	MCIDAS CEP72 SPICE1 MDM1 BRCA1 STIL WDR62 C2CD3 CCDC78 CENPJ KIAA0753 CEP63 TRIM37 SASS6 CDK5RAP2 CEP152 NUP62 ALMS1 CHMP2A PLK4 NPM1 CNTROB E2F4	up	**
VANTVEER_BREAST_CANCER_METASTASIS_DN	0.0000229	0.0005602	0.5756103	0.4429935	1.905336	116	TRIP13 CA9 HJURP CP CENPF NDC80 DEPDC1 CDCA7 KIF14 TSPYL5 GMPS ASPM CENPA ECT2 CCNB2 PRC1 CD163L1 DTL MELK BUB1 AURKA RRM2 TMEM45A GPSM2 ORC6 MAD2L1 PFKP NUSAP1 IGFBP5 BIRC5 EZH2 RAB6B DIAPH3 INTS7 DLGAP5 CTSV TK1 KIF21A ASNS PSMD2 GNAZ	up	***
KEGG_LYSOSOME	0.0000331	0.0007661	0.5573322	-0.3809525	-1.905126	109	ACP5 MCOLN1 LIPA CTSW MANBA GNPTAB FUCA1 LAMP1 SLC11A1 GGA2 MAN2B1 ARSB ASAH1 GM2A CLN5 ATP6V1H PPT1 GAA TPP1 CTSD LAPTM5 ATP6V0D2 M6PR GLB1 HEXB HGSNAT CTSS CTSZ ATP6V0B DNASE2 IDS ENTPD4 AP3B1 CLN3 ATP6V0D1 CD164 SORT1 AP1G1 GALC ATP6V0C	down	***
GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN	0.0000004	0.0000172	0.6749629	0.4216163	1.905051	172	TRIP13 BDH1 PAGR1 PDCD2L TPX2 RBBP8 CDC25A UMPS MYBL2 PRC1 APOL2 MELK DNPH1 EXO1 STAP2 EMC9 AUNIP AURKA POLA2 CDCA5 RAD54L CHAF1B B3GNTL1 ZNF443 CHEK1 TRMT2A BRIP1 BLM PPIL1 CKS1B TMEM106C EXOSC2 CENPJ UCK2 BIRC5 POLR3K NCAPG SMG9 PGBD2 MRPL17 SF3B3 RNASEH2A LZTR1 SNRNP25 PARS2 CCNE1 DNAJC17 RAD51D DTYMK ZNF239 JMJD4 LRWD1 RAD50 GEMIN6 PFAS CENPM FBXO22 PRMT1 GINS3 RCC1 ZNF780A CCNA2 SCO2 DCPS PDAP1 WDR77 TUBA4B ATOX1 RAD51 ZWILCH PFKM CDK5 LIF	up	***
ZHENG_GLIOBLASTOMA_PLASTICITY_UP	0.0000002	0.0000105	0.6901325	0.4096781	1.904384	211	HELLS CPLX2 CDC45 CP NUP107 UGT8 CCNB1 UBE2T NDC80 SDK2 RACGAP1 ALDH1L1 ANLN BCAS1 POLE SPP1 ASPM PLK1 NUF2 CDCA8 AURKB ECT2 TPX2 CCNB2 FIGNL1 UHRF1 MCM4 MCM2 PRC1 DPYSL4 CCNF CDT1 MELK EXO1 KIF23 BUB1 TOP2A AURKA CLSPN RRM2 GCAT RAD54L MCM3 LMNB1 RBP1 LIG1 CD24 ASS1 MAD2L1 PFKP RAD51AP1 SPRY1 INCENP CKS1B NUSAP1 APLP1 BIRC5 TESC TRIM2 FEN1 SPAG5 SEMA3A CRLF1 CTSV ATP9A KIF22 EPHB2 TK1 CENPQ	up	***
GO_POSITIVE_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION	0.0029831	0.0290082	0.4317077	-0.5929460	-1.903622	18	IL1B GATA3 IL18R1 TRAF6 IL6 MALT1 CD81 IL18 NLRP3	down	*
KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN	0.0000005	0.0000206	0.6594444	-0.3585965	-1.903546	178	WEE1 DENND5A LRRC8C SNX10 CLDND1 TTC7B CD44 CTSW ST3GAL6 AQP9 CYB5R3 BCL2A1 FGR ANXA1 KLF10 KLF6 PRSS12 GATA3 IL18R1 CRTAM TXN PPP3CC AHNAK CASP1 YBX3 KLF4 BCHE CTSD ITGAX HOPX ID2 CCL4 RECK PRF1 MBD2 SH2D2A N4BP1 IL7R MAPRE2 CD160 GABARAPL2 GSTO1 EEA1 DAPK2 CD7 DYM CST7 FOS KRTCAP2 FOSB CHPT1 PIM1 FCGRT TOB1 JUND RNF138 IL18RAP	down	***
LIAN_LIPA_TARGETS_6M	0.0002040	0.0034972	0.5188481	-0.4290351	-1.903299	61	CXCL3 ACP5 HMOX1 MS4A7 FCN1 SLC15A3 MARCO SLC11A1 IGSF6 LILRB3 PLA2G7 MSR1 MPEG1 MYRIP ATP6V0D2 FCER1G MMP19 KLRB1 UTRN C1QA CSTA	down	**
GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN	0.0000005	0.0000208	0.6594444	-0.3584844	-1.902951	178	SNX10 RAPGEF2 CLDND1 CD44 TXNL1 LONRF1 SLC39A8 ARL8B WBP4 LYRM4 WWC2 DNAJC18 BMP1 CARD16 ADA TNIP3 RANBP9 CLN5 NDEL1 BTG3 ATP6V1H CD58 PTPN12 CSRNP1 CASP1 PLAUR PLEKHM3 DRAM1 SOCS2 VRK2 CLIC4 FMNL3 NFKB1 CDS2 IRAK2 PNRC1 INHBA N4BP1 CMTM6 HCK BTG1 SLC25A25 INO80C ETV3 PSMA1 WTAP IFRD1 LYRM1 PSTPIP2 OSM TNFRSF9 TAGLN2 ACSL1 CALM1 PIK3AP1 CPA3 DUSP5 LRRC32 GPR84 PHF11 TNFAIP8 DIXDC1 TRAF1 PLGRKT NFKBIA ITCH NABP1 SPHK1 IRF2 CSF2RB SERPINE1 CLEC4E DCUN1D3 EYA3	down	***
REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	0.0000000	0.0000012	0.7337620	-0.3483072	-1.902109	219	CLEC1B PECAM1 CLEC3B F2RL3 P2RY1 TRPC3 FYN MMRN1 CTSW TBXA2R CDC42 CD9 GAS6 RHOA CD36 RAPGEF4 RAP1A GNGT2 ANXA5 ABHD6 GNG7 CRK SRGN PDGFA RHOB CFD ARRB1 DGKE THBS1 MPL FAM49B ABCC4 SELP FCER1G PLEK GNAQ PIK3R5 GNAI2 VWF TGFB2 PHACTR2 CYB5R1 RAC2 RHOG PIK3R1 PRKCE GRB2 CAP1 YWHAZ TAGLN2 PLCG2 CALM1 PRKCG DGKG DAGLA STXBP3 TGFB1 VAV3 TMX3 CDC37L1 GNAI1 GNG5 GNB4 APLP2 ORM2 GNA13 ACTN2 LAT WDR1 ARRB2	down	***
GO_PROTEIN_LOCALIZATION_TO_CHROMOSOME_CENTROMERIC_REGION	0.0006175	0.0087606	0.4772708	0.6520818	1.902049	19	NDC80 TTK AURKB CENPA CDT1 SPDL1 BOD1 CDK1 TRAPPC12 MTBP CENPQ	up	**
REACTOME_G1_S_SPECIFIC_TRANSCRIPTION	0.0004548	0.0068185	0.4984931	0.5924105	1.901559	27	CDC45 CDC6 TFDP2 TYMS CDC25A ORC1 CDT1 RRM2 CDK1 E2F1 CCNE1 TK1 HDAC1 LIN37	up	**
GO_REGULATION_OF_WATER_LOSS_VIA_SKIN	0.0008081	0.0107562	0.4772708	0.6450132	1.901492	20	TP63 FA2H ABCA12 KRT16 LSR GRHL3 CLDN1 HRNR FLG TMEM79	up	*
GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN	0.0000013	0.0000480	0.6435518	-0.3587145	-1.901382	181	GPR17 SLC31A2 CXCL16 EDNRB HVCN1 SOWAHC U2AF1 RAPGEF2 PTPRE WDR74 ALAS1 BCL2A1 IL1RN FAM49A FGR PLXNA2 SDE2 KLF10 PTX3 SLC7A11 ABHD6 SRGN SPI1 PDGFA RAB12 PLAUR REST SOCS2 GPR85 IRAK2 ID2 CCL4 PNRC1 GCA SPRYD7 HCK PROCR NINJ1 SERTAD2 GPBP1 CD80 ETV3 PLK3 PPP1R15A IFRD1 PSTPIP2	down	***
MIR7844_5P	0.0000085	0.0002446	0.5933255	-0.3780337	-1.900848	127	RTKN2 ABHD5 P2RY1 ST3GAL6 HMGCR PRKAR1A ZEB2 STARD4 ZNF385D ASAP1 PPP1R15B RAB33B IFI30 RNF182 PTX3 NFE2L2 CRK ZEB1 ZNF24 DOCK9 VIM FRMD4A CAPZA2 ELK3 ZMPSTE24 TMEM9B METAP1 EBF2 ELOVL7 SNX2 STX7 SKIL FSD1L NAA30 CELF2 CTTNBP2 MAPK8 ABHD13 SCARA5 RIMKLB LDLRAD4 EPN2 LRP12 CYB5R4 EPHA4 MEX3C CTSC RAB2A MIER3 HERPUD1	down	***
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4	0.0000005	0.0000211	0.6594444	-0.3586559	-1.900149	173	LPIN2 DLC1 CD55 LTA4H FBP1 SLC16A4 RAPGEF2 FOLR1 HSD17B11 NEDD4L CITED2 QKI SLC39A8 NR3C1 NEDD9 EDEM1 APOD CYB5A GLS MALL BTG3 TIPARP ARRB1 DAAM2 ZFAND5 PMM1 AQP4 HOPX SFTPD PER1 DUSP1 ELK3 VAMP5 RUFY3 RPS6KA2 SCEL AQP3 NDNF RHOBTB2 SFTPB BMP3 ATP11A ARHGEF10 AK1 NPR1 UNC13B REL GPRC5A PELI1 ALDH3B1 C1orf116 MEIS3P1 APLP2 MR1 GEM ICAM1 SLC34A2 PARM1 CEBPD MEGF9 GPD1L LIMCH1 NFKBIA TTC19	down	***
HUANG_GATA2_TARGETS_UP	0.0000072	0.0002088	0.6105269	-0.3768486	-1.900010	128	SLC12A6 GREB1 HHEX MNDA LPXN RAB44 CD44 YPEL5 TGFBR2 TXNIP CD93 SRGN SPI1 CST3 TAPT1 CEBPA CDKN1A ALOX5AP EVI2A N4BP2L1 AFF1 BTG1 EMP3 RAB31 KCTD12 TYROBP RHOG GSTO1 GLIPR1 GMFG PRORSD1P ATP6V0D1 MYL12A DGKG CPA3 DOK3 TGIF1 HBP1 GABARAPL1 TSPO SELPLG TNFAIP8 ACADM KIT GPR171 SAMSN1 IL16 LYZ TMEM50A CDKN1B SH3BGRL3 UBA6 CLEC4E	down	***
RICKMAN_HEAD_AND_NECK_CANCER_D	0.0004685	0.0069706	0.4984931	0.5918934	1.899899	27	MUC5B LTF TF CCL19 ZG16B PROM1 TFF3 AGR2 BPIFB1	up	**
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_DN	0.0000046	0.0001449	0.6105269	0.4257147	1.899188	151	HELLS CEP89 MCM10 NEK2 CENPF IGF2BP3 MPP6 DEPDC1B GINS1 RACGAP1 IQGAP3 E2F8 GMPS AURKB CDC6 TPX2 CCNB2 KNOP1 ORC1 MELK HMMR EXO1 KIF23 MKI67 KIF15 DPY19L1 MED12L SAE1 MPO RRM2 MRPL27 KIF11 CDC25C CCDC58 AHCY RAD51AP1 BRIP1 CXCL9 NCAPG2 RNPC3 CENPH BIRC5 NEIL3 SPAG5 GBP5 PA2G4 TUBG1 TACC3 ARL6IP4 LRWD1 GALNT3 ATAD5 COX10	up	***
REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	0.0000133	0.0003555	0.5933255	0.4453291	1.898855	106	BUB1B NUP107 CCNB1 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA CCNB2 DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 CDCA5 MAD2L1 CENPO SPC24 INCENP CDK1 CENPH BIRC5 KIF2A DYNLL2 CENPP RANGAP1 TUBB2A TUBA3D TUBA8 CENPQ NUP85 CENPK CKAP5 CDC20 CENPM DYNC1LI2 CENPT	up	***
GO_NEGATIVE_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR_VIA_HOMOLOGOUS_RECOMBINATION	0.0005315	0.0077412	0.4772708	0.7564348	1.898597	11	PARPBP POLQ MAGEF1 TP53BP1 HELB RECQL5 MAD2L2 UBQLN4	up	**
GO_CILIARY_BASAL_BODY_PLASMA_MEMBRANE_DOCKING	0.0000691	0.0014134	0.5384341	0.4578376	1.898460	86	CEP72 CEP89 RPGRIP1L NEK2 RAB3IP MKS1 CEP70 PLK1 DCTN2 HAUS5 CEP250 FBF1 ODF2 SFI1 C2CD3 IQCB1 CDK1 CEP97 CENPJ TCTN2 FGFR1OP CEP63 CEP192 NPHP1 TUBG1 NINL CKAP5 TCTN1 CDK5RAP2 HAUS6 HAUS4 CEP152 B9D1 ALMS1 CEP164 MARK4 CLASP1 KIF24 CEP290 DYNC1H1 PLK4 AKAP9 PCNT	up	**
MODULE_124	0.0000554	0.0011761	0.5573322	0.4536282	1.897738	91	DDX11 CCNB1 IGF2BP3 NDC80 TBRG4 CDK4 PLK1 PTTG1 E2F3 CCNB2 CDC25A NCAPD2 DCTN2 SMARCC1 KIF23 KNTC1 BUB1 KIF2C MAD1L1 EMG1 ACTL6A MAD2L1 PPP5C CDK1 BIRC5 E2F1 TAF6 CCNE1 CDK3 KIF22 TCEA1 CDC7 RRP9 POLR2J NEK4 POLR2I RCC1 CCNG1 CCNA2 SMC2 CHERP CDC25B UBE2C	up	**
GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_UP	0.0000009	0.0000352	0.6594444	-0.3640045	-1.897658	156	LPIN2 EGR2 C5AR1 CLEC10A FXYD2 NUDT9 C3orf70 MOB1B SPG21 NAAA SDE2 C1orf21 BTG2 PBX3 STOM TMEM38B CST3 ATP10A PTPRO CASP1 BST1 DRAM1 MARVELD1 TLR4 CD302 SLC6A6 CMTM6 PRCP SERTAD2 RBPJ OASL SERPINB8 C1QA RAC2 CCDC50 OSTM1 UBAC2 RNF24 SIGLEC1 RRAS MBP CD74 NUP153 KCTD10 IQSEC1 SP100 TRAF1 S100A4 TTC28 B3GNT2 SNAP29 MMD TMCC3 NRP2 NCF1 SLC38A2 FPR1 PLEKHA2 PLXDC2 NFAM1 PPWD1 PPIP5K2 SURF6	down	***
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP	0.0000006	0.0000232	0.6594444	-0.3565245	-1.897476	177	WEE1 CXCL3 RAMP3 SOWAHC IL1B TMEM170B CCRL2 ST3GAL6 HMGCR SLC15A3 VAPA HSPE1 EIF4A1 EIF1 MAP3K8 NLK PPP3CA FAM122A CSRNP1 C9orf72 ID2 ELK3 ELMSAN1 DSE MATK PPP2R5A PAFAH1B1 MAFF USP25 PRKRA IL6 RYBP SOCS3 RAB8B PPA2 LRCH1 MSRB3 ATP11A FOXN2 PPP1R15A GSTO1 FBXO11 ENPP4 PCGF5 TSPYL1 ATP6V0D1 EHD1 ZRANB1 TGIF1 CD86 IRS2 PPIG ADAM10 PDE4B ETS2 GEM ICAM1 NT5C2 IER5 IQSEC1 CXCR4 HNRNPK EPHA2 TRAF1 TMEM109 GPR171 ANXA11 LDLR ENY2	down	***
GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP	0.0000002	0.0000089	0.6901325	0.4153376	1.897266	185	FOXM1 CENPF TSFM TTK GMPS NABP2 PLK1 ECT2 ESPL1 RBBP8 MCM2 RAD54B TYMS MYBL2 SHMT2 CDT1 SPDL1 RANBP1 MELK EXO1 KIF23 KIF15 PUS7 NUP155 KIF2C MCM7 RRM2 RBM28 PDCD5 LMNB1 MAD2L1 DSCC1 EHF CNPY2 SKP2 PABPN1 GMNN GOT2 TRAP1 MCAT ITPKA FEN1 EZH2 CHCHD3 KIF22 DTYMK PKP4 FHL2 TRAF3IP1 ELAC2 CDC7 RAD50 GEMIN6 TIMM13 CKAP5 CENPM FAF1 LRRC59 PELO THOC5 PRMT1 CKAP2 GINS3 IL12RB2 RCC1 STK39 KLHL7 GLO1 RFC5 PAXIP1 SMC2 NMT1 NCAPD3 TUBA1C RAD1 DNM1L PPP1R14B COX17 BRIX1 CORO1B C9orf40	up	***
GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_UP	0.0000008	0.0000320	0.6594444	-0.3573640	-1.897191	174	IL1A MIR22HG CCRL2 NEDD4L CDC42EP2 INPP5A NR3C1 IL23A ATP2B1 HBEGF MTF1 TNIP3 ANPEP KLF6 PTX3 HLX SERPINB9 SLC25A37 CD93 EPM2AIP1 MCL1 IL10 PTGIR PPP6R3 ZBTB43 CLK4 DNTTIP2 INHBA IL24 NINJ1 EMP3 PKIG HCAR3 DCP1A IL6 OASL NXF1 SERPINB8 STAT4 HRH1 PLK3 RHOG PPP1R15A FERMT2 CCR7 ENTPD4 TNFRSF9 HIVEP2 FOXO3 ING3 EHD1 SOD2 PDE4B ETS2 CCL20 ICAM1 TNFAIP8 NBN RIPK2 SIK3 NLRP3 TRAF1 OSER1 MAP3K4 NFKBIA CYTH1 DAZAP2 IL16 TRIM36 PMAIP1 SNW1 LAMP3 WNT5A MTSS1 ANKHD1 STARD5 NKTR DUSP22 CFLAR PTGS2 JARID2 IL32 AKAP13 KBTBD2 EBI3	down	***
MARSON_FOXP3_TARGETS_UP	0.0002239	0.0037761	0.5188481	-0.4276174	-1.897010	61	SWAP70 PDLIM2 LRRC8C CD44 SAMHD1 MALAT1 GM2A CYB5A MCL1 VIM ARHGAP9 MAPRE2 MYO1C ETS1 RAC2 OSBPL9 IRF8 MBNL2 CELF2 NKG7 CD81 SERINC3 TIAM1 S100A4	down	**
GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_DN	0.0000020	0.0000699	0.6272567	0.4201638	1.896297	166	C1GALT1 KIF20A MDM1 RUVBL1 CDC45 TICRR BUB1B CENPF PBK KIF18B NDC80 PRIM2 GINS1 CDCA2 AGFG2 RACGAP1 NUF2 CDCA8 CENPA ESPL1 TPX2 FIGNL1 PRC1 CCNF DTL HMMR EXO1 CEP55 MKI67 TOP2A AURKA KIF2C WDR78 RRM2 CDCA5 GPSM2 LIG1 MAD2L1 CKAP2L CBY1 SKP2 KNSTRN NUSAP1 ASF1B BIRC5 GMNN NCAPG EZH2 CENPP CHCHD3 CCNE1 ALDH7A1 MNS1 TUBB2A TK1 IGHM PLEKHB1 ATAD5	up	***
GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT	0.0000000	0.0000000	0.9759947	-0.3117646	-1.896141	616	SMAD6 ANGPT4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB CDH5 ENG LYL1 ARHGEF15 FOLR1 ECSCR SOX17 CAV1 FOSL1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 NFATC3 HSPG2 HEG1 RHOA PDE2A APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM RAP1A TMEM204 ITGA5 CLEC14A HSPB1 LUZP1 FZD4 ANPEP NR4A1 JAM3 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 SPI1 TCF7L2 PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 MMP21 ROCK2 AMOTL1 NRARP FOXO1 TBX4 TNFSF12 TSPAN12 KLF4 ROCK1 ZFAND5 THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HPSE MIR24-2 RECK PIK3C2A ELK3 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS HES1 PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ FLT1 IL6 WASF2 PKNOX1 CD160 PSEN1 SOCS3 NDNF JUN NOTCH1 ETS1 JUNB EPC1 JAK1 RHOJ RAPGEF1 ACKR3 NPR1 NDST1 MCAM CD34 POGLUT1 RRAS KLF2 GJA4 PKD2 TREX1 WNT11 TGFB1 VAV3 ISM1 JMJD6 MIR23A MIA3 COL15A1 SOD2 MEIS1 MYOCD GATA6 GNA13 LTBP1 ADAM10 FGF2 IL18 VASH1 EGFL7 EPN2 OSR1 SEMA4A CXCR4 SP100 EPHA2 PARVA GLUL STK4 RAPGEF3 KIT EDN1 ETV2 FOXJ2 PTEN FGFR1 RORA LDLR NRP2 NAA15 ZFPM2 RNH1 FLT4 SPHK1 STARD13 EGR1 GREM1 SERPINE1 CTSH GJC1 HIPK1 ATF2 CX3CR1 C5 MAPK1 MYH10 ITGB1 HAS2 NOG MIR640 MIR2355 EFNB2 PIK3CG HEY1	down	***
GSE3982_EOSINOPHIL_VS_BCELL_DN	0.0000015	0.0000530	0.6435518	0.4200794	1.896070	167	FAT2 APOLD1 GBAP1 RACGAP1 E2F8 NIPSNAP1 UMPS GLDC MAP2K6 VILL SHMT2 AGK TOP2A LARS2 KLHDC4 MCM3 ACTL6A FBL PERP CAD SLC35E2B MRPS30 NAA40 CNPY2 TRIT1 ZNF32 CBX5 PPM1E AP3D1 NUP205 ETFB DNMT1 GOLGA3 FANCG CCNE1 TRADD OSBPL3 MYBBP1A CASP7 JMJD4 IL15RA ACAD10 AGPAT5 DAP3 IGHM ASNS DNMBP FN3KRP PLCH2 PFAS STOML2 MRPS33 MAB21L1 ABCD4 PRMT5 PMS2P1 FAM3C SMARCA4 SYBU ABCF2 MAP3K9 NDUFA8 INSL3 TCF3 PWP1 RRS1 IFI16 AKR7A2 KCNH4 DHX57 SLC38A10 UTP18 PSME1 PRPSAP2 TCFL5 PMVK	up	***
GO_PHOTOPERIODISM	0.0030967	0.0298634	0.4317077	-0.5458593	-1.895871	22	SIK1 CRY2 RBM4 PER3 USP2 FBXL3 PER2 ID2 PER1	down	*
GO_POSITIVE_REGULATION_OF_URINE_VOLUME	0.0039051	0.0356216	0.4317077	-0.7131130	-1.895859	10	EDNRB INPP5K NPR3 GNAI2 NPR1 ADORA2A EDN1 HAS2	down	*
REACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	0.0034868	0.0328707	0.4317077	-0.6127168	-1.895676	16	HES1 RBPJ MAML2 NOTCH1 KAT2B CREBBP FLT4 SNW1 HEY1 EP300	down	*
chr11q23	0.0000868	0.0017097	0.5384341	-0.4069506	-1.895648	78	SIDT2 SC5D DDX6 PAFAH1B2 FXYD2 DSCAML1 CBL RBM7 RN7SKP273 PTS TREH USP2 CADM1 SIK2 BACE1 TECTA RNY4P6 SCN4B MPZL3 SDHD MCAM FXYD6 TAGLN IL18 SIK3 DIXDC1 TBCEL CD3G COLCA2 ZBTB16 RNF214 ARHGEF12 CD3E	down	**
GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_UP	0.0000009	0.0000353	0.6594444	-0.3617780	-1.895267	163	RAB11FIP1 NLRC4 PPARG SOWAHC SNX10 CD44 PDE1B CAV1 IL23A CCNL1 RBM7 MCTP1 SBDS C16orf89 PPP1R15B MAP3K8 CRK PTPN12 RAB12 TNFSF15 VASP RMDN3 FBXL3 NFKB1 ATF3 IRAK2 PLEK GCA SPRYD7 KPNA3 FAM102B ETF1 SLC25A25 VPS37A PPP6C MITF CPEB4 FOXN2 PPP1R15A MALT1 PELI1 PTP4A1 MAPK8 TREX1 PIK3AP1 SORT1 EHD1 TMX3 SMCR8 CRY1 PLEKHO2 PDE4B ABL2 XKR8 NLRP3 NFKBIA MRPL32 TLK2 GSPT1 SPATA13 SLC16A10 UBAP1	down	***
GO_HISTONE_KINASE_ACTIVITY	0.0008085	0.0107562	0.4772708	0.7039762	1.894797	14	CCNB1 AURKB PRKCA AURKA CHEK1 CDK1 PRKAA2	up	*
GO_REGULATION_OF_RESPONSE_TO_WOUNDING	0.0000032	0.0001048	0.6272567	-0.3685981	-1.894793	145	TNR AJAP1 ADTRP WFDC1 WNT4 THBD CAV1 TBXA2R HMGCR CD9 TGFBR2 SCARF1 CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 CLEC7A ANXA5 NFE2L2 NDEL1 GRN CRK PDGFA FOXC2 IL10 KLF4 PLAUR THBS1 CDKN1A SELP HPSE TLR4 FCER1G PLEK UBASH3B KREMEN1 STK24 KANK1 CNTF DUOX1 ENPP4 PRKCE RTN4R CD34 SRSF6 EPPK1	down	***
GO_DNA_REPAIR	0.0000000	0.0000000	0.8753251	0.3849952	1.894676	448	HMGA2 TRIP13 DDX11 FOXM1 EYA1 RUVBL1 CDC45 TICRR PARPBP FANCI CHEK2 EYA2 TIMELESS POLQ UBE2T PAGR1 PIF1 BRCA1 NPAS2 PMS2P5 POLE NABP2 PTTG1 WDR70 FIGNL1 RBBP8 UHRF1 MCM4 MCM2 RAD54B PMS2 XRCC2 DTL CIB1 MCM8 LIG3 GINS4 SMUG1 MAGEF1 RUVBL2 EXO1 NUDT1 CHAF1A TP53BP1 POLM RHNO1 FANCA AUNIP EME1 REC8 ATR POLD2 SMARCAL1 MCM7 ASCC2 CLSPN MMS22L CDCA5 PRKDC TRRAP WDHD1 HELB RAD54L FANCD2 MCM3 CHAF1B EGFR LIG1 EME2 TOPBP1 CHEK1 ACTL6A RAD51AP1 XRCC1 PRMT6 BRIP1 RAD18 BLM PPP5C PML ERCC2 MNAT1 RECQL5 PARP1 POLN CDK1 POLE2 RFWD3 EEPD1 UNG DNA2 AP5Z1 NEIL3 FEN1 MAD2L2 RECQL4 RNASEH2A POLR2H FANCG DCLRE1C FANCF POLL MBD4 RAD9A MC1R KIF22 RAD51D SSRP1 COPS7B ESCO2 MGMT GINS2 FZR1 NUDT16 TCEA1 USP43 POLD1 POLB PARP9 COPS6 SLX4 CDC7 RAD50 UBQLN4 SUPT16H PALB2 TWIST1 HMGA1 ASCC1 RPA1 POLR2J FANCM UBE2V2 MCM6 MGME1 WRNIP1 XRCC4 MCM5 TDP1 ZRANB3 UIMC1 POLR2I IGHMBP2 PMS2P1 MSH4 PMS1 MCRS1 MSH2 NFRKB DTX3L RTEL1 RFC5 CEP164 INO80E RAD51 TNKS1BP1 EYA4 PAXIP1 NUDT16L1 SIRT6 PNKP TONSL PARG XPC MPG SWI5 TP53 NEIL1 APEX1 RAD1 DDB2 PIAS4 ACTR5 TMEM161A ERCC3 ALKBH2 PARP2 TTC5	up	***
MODULE_75	0.0000000	0.0000002	0.7749390	-0.3311746	-1.893869	308	EREG IL1A FCN1 CD101 TEK CD55 IL1B MNDA EMP2 GPR65 INSIG1 FYN LY86 FCER1A AQP9 CHIT1 C5AR1 NCF2 CD1C GAS6 CD22 IGSF6 LILRB3 CD8A FGR ERG DNAJC3 CD5 HBEGF ADA BTG2 MAP3K8 KLF6 MS4A1 GATA3 IL18R1 GRN CES1 ZEB1 MTHFR PDGFA STAT5A BST1 TNFSF12 PTAFR DAB2 CCL3 CDKN1A CXCL2 SELL SELP CCL4 SFTPD CD53 PRF1 FCER1G CD300C EVI2A IL7R C4BPB IL24 ARHGDIB SNN BTG1 EMP3 CD8B AREG IL6 CTSS IL2RB OASL CD48 C1QA ETS1 TYROBP IFNGR1 PTGER4 CD83 IRF8 GMFG GPR183 OSM CXCL5 CST7 RUNX3 CR1 CD6 CD86 PDCD1 CD81 ORM2 CCR1 FCGRT CLEC2B CCL20 GEM GPX3 IL18 LAT CXCR4 CCR9 EPHA2 DAPK1 CD19 BCAT1 NFKBIA ADORA2A CTSC EDN1 CD3G KLRK1 AIM2 CREG1 IL16	down	***
GO_REGULATION_OF_T_CELL_CYTOKINE_PRODUCTION	0.0023934	0.0245995	0.4317077	-0.5308134	-1.892897	25	IL1B GATA3 IL18R1 TRAF6 SMAD7 IL6 MALT1 TBX21 CD81 IL18 NLRP3	down	*
GO_NEGATIVE_REGULATION_OF_LIPID_LOCALIZATION	0.0005434	0.0078747	0.4772708	-0.5029839	-1.892685	34	ABHD5 PPARG PLA2G10 PCSK9 MIR27B MIR146A ABCG1 APOC1 THBS1 NFKB1 IL6 PNPLA2 IRS2 CRY1 SREBF2 NFKBIA	down	**
GO_HEAT_GENERATION	0.0040068	0.0362223	0.4070179	-0.6373490	-1.892290	14	IL1A EDNRB IL1B ADRB1 ADRB2 PTGER3	down	*
GO_HOMOPHILIC_CELL_ADHESION_VIA_PLASMA_MEMBRANE_ADHESION_MOLECULES	0.0000341	0.0007866	0.5573322	0.4438513	1.892197	107	CEACAM1 CDHR2 PTPRT PCDHGA10 IGSF9 CDH17 FAT2 PCDHGA9 PCDHGA5 PCDHGA7 SDK2 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 IGSF11 VSTM2L PCDHGB4 PCDHGA11 PCDHGA8 CLSTN3 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 SDK1 PCDHGA3 IGSF21 MYOT FAT1 CDH3 PCDHGA2	up	***
REACTOME_CILIUM_ASSEMBLY	0.0000034	0.0001106	0.6272567	0.4165135	1.891314	177	CEP72 CEP89 RPGRIP1L NEK2 RAB3IP MKS1 TUBB2B IFT122 TTC26 CEP70 PLK1 IFT27 EXOC3 CCT2 DCTN2 HAUS5 CEP250 BBS1 KIF3B FBF1 EXOC4 CCT5 ODF2 SFI1 IFT43 WDR60 IFT172 KIF3C CNGB1 C2CD3 IQCB1 CDK1 CEP97 CENPJ CCT3 TCTN2 DYNLL2 SMO FGFR1OP IFT52 CEP63 BBS5 CEP192 NPHP1 EXOC7 TUBG1 NINL TUBB2A TUBA3D TUBA8 CNGA4 TRAF3IP1 CKAP5 WDR34 GBF1 TCTN1 CDK5RAP2 WDR35 HAUS6 DYNC2H1 HAUS4 UNC119B CEP152 B9D1 ALMS1 CEP164 CLUAP1 TUBA4B MARK4 TCTEX1D1 TTC30B TUBA1C CLASP1 KIF24 CEP290 DYNC1H1 PLK4 AKAP9 PCNT RAB11FIP3 KIFAP3	up	***
BIOCARTA_NKT_PATHWAY	0.0031991	0.0306544	0.4317077	-0.5444715	-1.891051	22	IL18R1 CCL3 CCL4 TGFB2 IFNGR1 CCR7 CCR4 TGFB1 CCR1 CXCR4 CSF2 IL5 CD4 CCR5 IFNG	down	*
REACTOME_RESOLUTION_OF_ABASIC_SITES_AP_SITES	0.0010400	0.0131014	0.4550599	0.5395638	1.891026	37	POLE LIG3 SMUG1 POLD2 LIG1 XRCC1 PARP1 POLE2 UNG FEN1 MBD4 POLD1 POLB RPA1 RFC5 PNKP PARG MPG NEIL1 APEX1 PARP2 POLD3 RFC3 POLE4 RFC4 PCNA ADPRHL2 TDG NEIL2 RPA3 POLE3 MUTYH	up	*
MODULE_244	0.0000043	0.0001375	0.6105269	0.4202107	1.891024	162	TRIP13 DDX11 AK4 CHEK2 NEK2 PRIM2 TTK CDK4 KIF14 GMPS POLE PLK1 ORC1 CCT6A EPHB1 NME1 MELK KIF23 MKI67 HLTF KIF3B BUB1 TOP2A POLD2 KIF2C COASY RAD54L KIF11 MCM3 PEX6 LIG1 CHEK1 BLM CDK1 POLE2 MERTK TRAP1 PSMC4 RECQL4 STK11 ILF2 GSS KIF22 MAPK13 EPHB2 TK1 DTYMK POLD1 MAT1A CDC7 POLR2J MCM6 MED24 SRPK2 DDX23 NEK4 PFKFB4 PMS1 MSH2 PRIM1 STK38 RFC5 NME4 RAD51 CDK5 SMC2 CENPE MTHFD1 SEPHS1 TIMM44 MAP2K2 ERCC3 ROR2	up	***
GO_POSITIVE_REGULATION_OF_MACROPHAGE_ACTIVATION	0.0047970	0.0413990	0.4070179	-0.5685016	-1.890920	19	IL1RL1 IL10 THBS1 CEBPA CCL3 TLR4 HAVCR2 CTSC TREM2 WNT5A	down	*
CHEN_ETV5_TARGETS_SERTOLI	0.0020967	0.0222363	0.4317077	-0.5999730	-1.890890	17	THBD CD36 ARSB CLEC7A CD53 PLEK IL6	down	*
MODULE_191	0.0012542	0.0151228	0.4550599	0.6904650	1.890861	15	LTF TF CCL19 CP	up	*
REACTOME_PROCESSING_OF_DNA_DOUBLE_STRAND_BREAK_ENDS	0.0002073	0.0035367	0.5188481	0.4911945	1.890697	56	TIMELESS BRCA1 RBBP8 EXO1 TP53BP1 RHNO1 ATR CLSPN TOPBP1 CHEK1 BRIP1 BLM DNA2 RAD9A RAD50 RPA1 UBE2V2 UIMC1 CCNA2 RFC5 SIRT6 RAD1 PIAS4 TOP3A ATRIP RNF8 HERC2 RMI1 TIPIN PPP4C RMI2 RFC3 BARD1 RFC4	up	**
chr2q22	0.0047111	0.0408360	0.4070179	-0.6852515	-1.890286	11	ZEB2-AS1 ZEB2 GTDC1 THSD7B KYNU CXCR4 SPOPL	down	*
BIOCARTA_DC_PATHWAY	0.0047111	0.0408360	0.4070179	-0.6851702	-1.890062	11	CD5 CD33 ANPEP IL10 ITGAX CD7 CSF2 IL5	down	*
GO_POSITIVE_REGULATION_OF_ERK1_AND_ERK2_CASCADE	0.0000013	0.0000488	0.6435518	-0.3636111	-1.889591	153	FFAR4 HCRTR1 RAMP3 TEK SCIMP GLIPR2 P2RY1 RAPGEF2 BMPER BMP2 CD44 CCL3L1 C5AR1 HMGCR FGF10 MIR27B MARCO GAS6 CD36 RAP1A SPRY2 PDGFA NODAL ARRB1 CCL22 NPNT PDE8A CCL3 PTPRC CCL4 TLR4 MIR24-2 XCL2 GNAI2 DNAJC27 JUN NOTCH1 ADRA1A RAPGEF1 CCR7 ACKR3 GPR183 FGFR4 CD74 TGFB1 FPR2 MIR23A NQO2 CCR1 NPTN CCL20 ICAM1 FGF2 ARRB2 RIPK2 HAVCR2	down	***
GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN	0.0000010	0.0000387	0.6435518	-0.3562490	-1.889365	182	ST3GAL6 ELF2 VAMP2 S1PR1 MAL LAMP1 TGFBR2 HEG1 TXNIP ASAH1 EIF1 BTG2 EIF5 LITAF SRGN PDE4D MCL1 CD37 EFCAB14 MOAP1 SDCBP LEPROTL1 TPP1 LAPTM5 RRP8 IL7R FOXN3 BTG1 RBM39 AREG NXF1 JUNB DUSP8 WTAP SP3 DDX5 THUMPD1 GPR183 HERC2P3 YWHAZ CLN3 SNRK MOB1A CDK17 CALM1 SRSF6 ZBTB1 HBP1 TOB1 RGS2 SPOCK2 PDE4B MBNL1 GTF2B CCDC69 CXCR4 EPHA4 ALDH2 BRWD1 IFFO1 CYTH1 DAZAP2 MT2A EIF4G2 ARHGEF18 CDC14A USP4	down	***
GO_HUMORAL_IMMUNE_RESPONSE_MEDIATED_BY_CIRCULATING_IMMUNOGLOBULIN	0.0001060	0.0020336	0.5384341	0.4552365	1.888796	84	IGHV4-61 IGHV4-4 IGLV3-27 IGKV1-17 IGKV3-15 IGKV1-16 ZP3 FCER2 IGKV4-1 IGLC7 IGKV2D-28 EXO1 FOXJ1 IGLV1-44 C6 C1RL IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGHG1 IGLV7-43 SUSD4 IGLV6-57 IGHM IGLV1-47	up	**
YU_MYC_TARGETS_DN	0.0006247	0.0088285	0.4772708	-0.4493123	-1.888725	47	ACP5 MNDA GGA2 LIFR MS4A1 CD37 RBMS1 PTPRC HLA-DQA1 BTG1 KLF2 CD74 CD1D MACF1 SPIB CTSH MAP4K2 IL10RA PLD4 ARID3B UNC93B1 PYGM BLK	down	**
PID_FANCONI_PATHWAY	0.0005309	0.0077409	0.4772708	0.5322395	1.888371	40	FANCI UBE2T BRCA1 FANCA ATR SSPO FANCD2 TOPBP1 CHEK1 BRIP1 BLM FANCG FANCF RAD9A RAD50 PALB2 RPA1 FANCM RFC5 FBXW11 RAD1 TOP3A ATRIP RMI1	up	**
GO_LUNG_GROWTH	0.0020691	0.0219985	0.4317077	-0.7911271	-1.888343	7	FGF10 SPRY2 TMEM38B MIR17HG	down	*
GO_MICROTUBULE_BASED_MOVEMENT	0.0000002	0.0000078	0.6901325	0.4021187	1.888310	239	KIF1A KIF12 KLC3 KIF20A DNAH2 AP3B2 UCHL1 KIF18B STK36 RACGAP1 IFT122 KIF14 SPAG17 TTC26 IFT27 DNAH3 DYNC1I1 KIF27 DNAH14 DNAI1 ARMC4 KIF23 BICD1 KIF15 COPG2 COPG1 KIF3B IFT43 KIF2C HYDIN WDR78 DPCD TEKT2 CCDC114 KIF11 BLOC1S1 WDR66 WDR60 NME5 DNAH8 IFT172 GAS8 KIF3C DNAH11 CCDC40 DRC1 KIAA0556 LRRC6 DNAH6 KIF5A AP3D1 SUN1 KIF19 KIF2A KIF7 SSX2IP DYNLL2 LCA5 DNAH5 IFT52 KPNB1 DLGAP5 SPG7 DNAH7 CCDC151 KIF22 KIF21A KIF20B TEKT3 SPA17 TRAF3IP1 KLC2 WDR34 AP3M2 DYNC1LI2 KIF21B DNAI2 WDR35 DYNC2H1 KATNB1 TTLL6 RSPH4A NEFH CATSPER1 SYBU ICK CLUAP1 DNAH1 TRAK1 RHOT2 CELSR2 MAPK8IP3 CAMSAP3 CENPE DTNBP1 SYNE2 TTC30B RASGRP1 TMEM201 KIF24 DNAL4 DNAAF1 DYNC1H1 MAK TEKT1 WDR63	up	***
GO_CORECEPTOR_ACTIVITY	0.0008234	0.0109260	0.4772708	-0.4851341	-1.888065	36	RAMP3 GPR15 RAMP2 TGFBR3 CD8A LY96 RECK CD8B CD80 ACKR3 CD86 CXCR4 FCRL1 ITGB1 LRP1 CD4	down	*
GO_NEGATIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION	0.0013855	0.0163078	0.4550599	-0.4993050	-1.887335	33	ACVRL1 PPARG CAV1 MIR146A PTPRM CAV2 RGCC THBS1 MIR24-2 FLT1	down	*
GSE45837_WT_VS_GFI1_KO_PDC_DN	0.0000013	0.0000467	0.6435518	0.4171054	1.887068	173	UBE2Z NIPSNAP1 NDUFS6 SHMT2 NME1 NDUFB8 DNPH1 NUDT1 KCNN4 RFXANK SAE1 PDCD5 AHCY PSMD4 PFKP MRPS11 C7orf26 UQCR11 ZNF32 FASTK RBCK1 NPM3 TCF20 ETFB UCKL1 DDT MPI SNRNP25 MZT2A MZT2B TRADD MRPS34 HDHD3 ARF5 ARL6IP4 LAMTOR2 DAP3 COG4 AAMP COPS6 CCT7 YARS2 STOML2 ZNF428 CLASRP TBCA PRMT1 SRPK2 MCM5 CD2BP2 LSM7 NDUFS7 POLR2I EIF3K COPZ1 SNRPD2 PRPF31 ETHE1 UQCRQ GNA12 MPG MTHFD1 COX6B1 HEMK1 RANGRF MRPS16 DFFB PARL ADSL LCMT1 AP2B1 PLEKHJ1 SLC35C1 DDX49 GRHPR EBNA1BP2 XRCC6 TRAPPC2L DRAP1 PSMD8	up	***
GO_NEGATIVE_REGULATION_OF_NITRIC_OXIDE_METABOLIC_PROCESS	0.0024296	0.0248720	0.4317077	-0.6475750	-1.886403	13	ACP5 CAV1 SIRPA IL10 ROCK2 PTGIS CD34 TSPO	down	*
GO_ORGANELLE_FISSION	0.0000000	0.0000001	0.7881868	0.3891280	1.886342	365	TRIP13 SPICE1 CHEK2 BUB1B NEK2 CCNB1 CENPF MND1 KIF18B NDC80 TTK SMPD3 RACGAP1 KIF14 L3MBTL1 ANLN ASPM MSTO1 PLK1 NUF2 CDCA8 AURKB PTTG1 ESPL1 CDC6 ACOT8 TPX2 FIGNL1 RAD54B MYBL2 PRC1 TDRKH NCAPD2 ZWINT CDT1 SPDL1 RANBP1 KIF23 STAG3 MKI67 CUL9 BOD1 CUL7 FBXO43 KNTC1 KIF3B BUB1 FANCA MSX2 TOP2A MAP10 AURKA EME1 REC8 SYCP2 TPR KIF2C MAD1L1 MSX1 CDCA5 RAD54L TOM1L1 KIF11 FANCD2 HORMAD1 CDC25C EME2 CHEK1 MAD2L1 DSCC1 PKMYT1 BRIP1 PSRC1 INCENP KNSTRN NUSAP1 ANAPC5 CEP97 BIRC5 SUN1 DIS3L2 NCAPG STAT2 KIF2A SPAG5 EGF MTBP MAD2L2 KLHL22 KPNB1 MYO19 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 SEC16B TACC3 DHODH KIF22 HIRA RAD51D DNM1 AKAP8L FZR1 KIF20B ANAPC1 CDK13 COX10 SLX4 RAD50 ANKRD31 CENPK KLHDC3 SH2B1 MEI1 CDC20 TUBG2 AAAS CHMP4C FANCM CDK5RAP2 CHTF8 KATNB1 RCC1 PRMT5 NUP62 CEP85 MSH4 RAD51 CHMP1A CHMP2A AURKAIP1 SMC2 LIF MAU2 CENPE GOLGA2 FIS1 CDC25B UBE2C NCAPD3 MAP9 RAD1 RRS1 DNM1L CLASP1 NCAPH POGZ CHMP6 PDXP MUS81 DRG1 MLH3 WRAP73 C11orf80 DSN1 PEX11A FBXO5 LCMT1 NFE2L1 OPA1 NSL1 SLC2A8 MAD2L1BP	up	***
GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_BINDING	0.0049610	0.0425136	0.4070179	-0.6736783	-1.886132	12	SMAD6 BMP2 CDH5 NODAL INHBA MAGI2 BMP3	down	*
GO_INTERLEUKIN_1_BETA_PRODUCTION	0.0001479	0.0026707	0.5188481	-0.4100691	-1.886008	73	NLRC4 ACP5 IL1B MNDA LPL CD36 CARD16 CD33 CLEC7A HSPB1 FOXP1 SIRPA MEFV CASP1 CCL3 TLR4 CARD8 TYROBP CCR7 MALT1 SUCNR1 SERPINB1 ORM2 MR1 ARRB2 RIPK2 NLRP3 AIM2 EGR1 CX3CR1 TREM2 WNT5A HMGB1	down	**
BURTON_ADIPOGENESIS_PEAK_AT_16HR	0.0005065	0.0074325	0.4772708	0.5433048	1.885653	36	HELLS CDCA7 CDC6 MCM4 POLA2 MCM7 RRM2 SERPINA3 MCM3 CHAF1B ASS1 ASF1B FEN1 DNMT1 POLD1 HMGA1 MCM6 MCM5 ABCF2 RAD51 SMC2	up	**
BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP	0.0011099	0.0137783	0.4550599	0.5195398	1.885448	43	KIF20A CPSF6 GINS1 CCNB2 CPD PRKDC CD24 PON2 CCT3 PEG10 SNRPE CBX1 DUSP12 ENAH VIL1 ACLY SNRPD1 NT5DC2 ATAD2 CKAP4 MRPL9 UBAP2L	up	*
GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ENDOPLASMIC_RETICULUM	0.0001871	0.0032480	0.5188481	0.4600081	1.885177	78	RACGAP1 COPB2 GOLPH3L GOLPH3 KIF23 KIF15 COPG2 COPG1 KIF3B KIF2C KIF11 KDELR2 KIF3C TMED3 NSF KIF5A PICK1 STX18 KIF2A RAB6B TAPBP ATP9A COG7 KIF22 ARF5 COG4 KLC2 KDELR3 GBF1 ERGIC3 COPZ1 ARFGAP1 RER1 COPA ERGIC1 TMED9 CENPE COPZ2	up	**
MORF_FEN1	0.0005968	0.0085049	0.4772708	0.4975368	1.885123	52	FOXM1 CCNB1 CDK4 ESPL1 EIF3B ZWINT CCT2 CCT5 MCM7 MCM3 DNAJC9 SSBP1 CCT3 UNG FEN1 NUP205 VBP1 LMNB2 MCM6 SRSF1 POLR2I LSM4 ALG8 VDAC1 EIF4G1 MTHFD1 CHERP	up	**
MUELLER_PLURINET	0.0000000	0.0000012	0.7337620	0.3986121	1.884728	270	TRIP13 DDX11 BIK RUVBL1 CDC45 MCM10 CHEK2 BUB1B COIL CCNB1 POLQ MPP6 PHGDH TRAIP GMPS DNMT3B AURKB TPX2 CCNB2 MCM4 MCM2 MYBL2 GRB7 ORC1 CDT1 LSM5 NME1 HMMR EXO1 NUDT1 NLE1 SMARCC1 CHAF1A AURKA POLD2 RAD54L PASK MCM3 CDC25C AIMP2 CHEK1 ORC6 FBL DCTPP1 DSCC1 GEMIN7 BLM PHB MNAT1 PARP1 CASP6 CKS1B PAK1 CDK1 SIGLEC12 BIRC5 ATIC GMNN GOT2 UNG FEN1 POLR1C SPAG5 MRPS12 SNRPE RECQL4 PA2G4 KPNB1 PELP1 CCNE1 SNRPA RAD9A SALL4 TK1 MYBBP1A HDAC1 NOC2L ANAPC1 POLD1 COPS6 ELAC2 CDC7 RMND5B GEMIN6 ERBB3 HMGA1 POP7 FAM136A RPA1 MCM6 MCM5 SNRPD1 LSM7 SRSF1 AATF LSM4 WDYHV1 TCERG1 PRMT5 STRBP NME1-NME2 MSH2 CCNA2 RFC5 WDR77 RAD51 SUPT3H TARBP2 CENPE MTHFD1 TP53 SEPHS1 APEX1 SNRPC PNN	up	***
chr13q33	0.0023050	0.0238730	0.4317077	-0.5978569	-1.884221	17	FGF14-AS2 TPP2 ABHD13 TEX30 FGF14-IT1 NALCN EFNB2 ARGLU1 BIVM LIG4 FAM155A-IT1 ERCC5 FGF14 MYO16	down	*
GSE3982_DC_VS_TH2_UP	0.0000008	0.0000326	0.6594444	-0.3578235	-1.884121	170	GPD1 SMAD6 SLC31A2 TAL1 DCSTAMP THBD ENG LYL1 LMO2 C5AR1 CLEC10A SLC15A3 FUCA1 PILRA CD36 ANXA1 MAN2B1 CD33 SLC7A7 ABCG2 LITAF ANPEP PTX3 TNS1 ATP6V1H SETD3 CST3 CCL22 BST1 CPVL COQ10B UBTD1 MAP1LC3B ARNTL TPP1 TMBIM1 PDE8A CDKN1A MATK HLA-DQA1 CLN8 MITF HK3 CTSZ PPP1R15A CD83 PLCG2 FAM204A SORT1 CD1D TSC22D1 RGS2 PITPNA SESN1 PARM1 NLRP3 SLC2A9 ULK2 TMEM87A FAM13C C1orf115 CACNA2D3 UBAP1 CTSH	down	***
CTTGTAT_MIR381	0.0000010	0.0000362	0.6594444	-0.3559298	-1.883694	172	WEE1 DLC1 INSIG1 DDX6 QKI GTF2I SEMA6D UBR3 CLCF1 B3GNT5 EIF1 NLK ROCK2 ACSL3 KLF4 CEBPA UBE2E2 PNRC1 KPNA3 SIAH1 CREBRF ETF1 MITF HMBOX1 ETS1 JPH1 ELOVL7 MBNL2 RC3H1 CGGBP1 SNRK RHOQ NAP1L5 BTBD7 EPHA3 AZIN1 PDS5B KHDRBS1 CNOT7 HBP1 ANKRD12 STX12 PHF2 RNF2 CXCR4 EPHA4 SSH2 NFKBIA KIF1B ITCH ZFPM2 RNF13 RAB2A EIF4G2 MAP4 PSIP1 KALRN HIPK1 DCUN1D3 SLC38A2 CCNT2 XPO7 WNT5A UBE3A MTSS1 RNF111 NR5A2 RAB11FIP2 ARGLU1 SRRM1 SCAF8 SLC24A3 GRM8 JAG2 PDS5A MED13 UBE4A PRPF38B APPBP2 ZNF770 GID4 KLF12 PAPOLG BCL11B	down	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_UP	0.0000012	0.0000437	0.6435518	-0.3547286	-1.883200	174	CD300LF CD52 SASH1 DENND5A TAL1 HHEX PTPRE LPL LMO2 MYADM TGFBR2 PEAR1 ANXA1 CD33 ADAM17 ZNF503 BFAR PPP3CA IL18R1 TCF7L2 CYP4V2 PTPN12 EVI2B TACR2 ST3GAL2 STX3 PLBD1 ITIH5 ID2 TEF PLEK KLRD1 N4BP2L1 PRDM5 HLA-DQA1 HCK MYLIP RNF149 CTSS RGS18 RAB31 TYROBP GLIPR1 IRF8 PRKCE PTGER2 CD34 ACSL1 RHOQ PKD2 SPOP DDHD2 VAV3 TSC22D1 CD86 CD81 MEIS1 GEM IL18 IL18RAP	down	***
REACTOME_DNA_REPAIR	0.0000001	0.0000033	0.7049757	0.3986418	1.882855	260	EYA1 RUVBL1 FANCI CHEK2 EYA2 TIMELESS POLQ UBE2T BRCA1 POLE RBBP8 PMS2 XRCC2 DTL LIG3 SMUG1 EXO1 TP53BP1 POLM RHNO1 FANCA EME1 ATR POLD2 ASCC2 CLSPN PRKDC FANCD2 LIG1 EME2 TOPBP1 CHEK1 ACTL6A RAD51AP1 XRCC1 BRIP1 RAD18 BLM PPP5C ERCC2 MNAT1 PARP1 POLN POLE2 UNG DNA2 NEIL3 FEN1 MAD2L2 PIAS3 POLR2H FANCG DCLRE1C FANCF POLL MBD4 RAD9A RAD51D COPS7B MGMT TCEA1 USP43 POLD1 POLB COPS6 SLX4 RAD50 PALB2 ASCC1 RPA1 POLR2J FANCM UBE2V2 KDM4B XRCC4 TDP1 UIMC1 POLR2I MCRS1 MSH2 CCNA2 NFRKB RTEL1 RFC5 INO80E RAD51 EYA4 PAXIP1 SIRT6 PNKP PARG XPC MPG TP53 NEIL1 APEX1 RAD1 DDB2 PIAS4 ACTR5 ERCC3 ALKBH2 PARP2 INO80B MUS81 SPIDR TOP3A PRPF19 ATRIP RNF8 DCLRE1B MSH6 DCLRE1A ASCC3 POT1 HERC2 RMI1 XRCC5 TIPIN UVSSA PPP4C UBE2L6 POLD3 COPS7A RBX1 XRCC6 RMI2 MSH3	up	***
GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION	0.0000016	0.0000584	0.6435518	0.4141497	1.882824	179	HELLS HJURP RUVBL1 CDC45 CENPF CABIN1 TSPYL5 CENPA SOX9 MCM4 MCM2 MIS18A CAND1 CDT1 SMARCD3 SMARCC1 CHAF1A CENPL MCM7 CENPW MCM3 CHAF1B ZNHIT1 CENPO PIH1D1 ERCC2 MNAT1 PARP1 ASF1B CENPH GMNN GTF2E1 TAF6 TRAPPC12 PSMC4 VPS72 CENPP HIRA CENPQ ANP32E CHD5 ESR1 CENPK BAZ2A SUPT16H CENPV HNF1B CENPM HMGA1 RPA1 WNT10B MCM6 CENPT MCM5 NFE2 SMARCC2 SMARCA4 RAD51 GTF3C5 SOX12 XPC CENPE SRCAP SWI5 TP53 UBTF SMARCB1 ATF7IP DDB2 SART3 ERCC3 POGZ	up	***
GO_REGULATION_OF_B_CELL_PROLIFERATION	0.0003668	0.0057836	0.4984931	-0.4375368	-1.882500	54	MNDA CD22 CLCF1 ADA WNT3A TFRC IL10 BST1 CDKN1A PTPRC TLR4 NCKAP1L TYROBP GPR183 RC3H1 PELI1 CD74 VAV3 IRS2 CD81	down	**
REACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS	0.0001754	0.0030699	0.5188481	0.4592804	1.882304	79	SAA1 HP IGLV3-27 IGKV1-17 HBA1 HBA2 IGKV3-15 IGKV3-11 IGKV1-16 STAB2 IGKV4-1 HBB IGKV2D-28 APOL1 IGLV1-44 HPR IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 COL3A1 IGLV7-43 COL1A1 COL1A2 IGLV6-57 COLEC11 IGLV1-47	up	**
GNF2_MSH2	0.0004672	0.0069603	0.4984931	0.5935075	1.881427	26	FANCI NDC80 GINS1 TOP2A MCM7 MCM3 LIG1 RAD51AP1 FEN1 SUPT16H MCM6 SNRPD1 TCERG1 MSH2 MSH6 LRPPRC SMC4 RFC4 ITGB3BP PCNA	up	**
GO_KERATINIZATION	0.0004693	0.0069787	0.4984931	0.5081009	1.880955	47	PCSK6 LIPM KRT5 PKP2 PKP1 ABCA12 KRT16 KRT15 HRNR FLG TGM1 PERP KRT18 CDH3 TMEM79 ST14 PKP3 PKP4 KRT19 PPHLN1 KRT8 SPINK5 KRTAP5-9 PRSS8	up	**
REACTOME_INTERLEUKIN_1_PROCESSING	0.0025044	0.0254525	0.4317077	-0.7877707	-1.880332	7	IL1A IL1B CASP1 NFKB1 IL18	down	*
MODULE_118	0.0000000	0.0000002	0.7749390	0.3900439	1.880302	337	RIBC2 TRIP13 PLAT DDX11 ENTPD2 FOXM1 BIK CDC45 TROAP BUB1B PROM1 PRSS2 CCNB1 CENPF IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 NDC80 SORD ECE2 GTSE1 KIF14 GMPS SPP1 MMP1 PLK1 CENPA PTTG1 TPX2 CCNB2 MCM4 MCM2 MYBL2 CCNF SRPK1 NCAPD2 ZWINT TNC CASP2 HMMR NUDT1 KCNN4 CHAF1A MKI67 PRB4 KNTC1 PAFAH1B3 TOP2A MYO10 CARD10 POLD2 MPO RRM2 SLC22A18AS RAD54L KIF11 MCM3 LMNB1 SOX4 SALL2 MDK RBP1 CD24 SLC9A3R1 TOPBP1 MAD2L1 SCAMP5 MSI1 ABCB9 PKMYT1 FADS2 CLDN9 MGLL RECQL5 CDKN2C TMEM106C PLOD2 KRT18 CDK1 EXOSC2 NPM3 E2F1 UNG PEG10 FEN1 EZH2 NUP205 TTI1 IGSF3 RECQL4 RNASEH2A TBX1 LGR5 DLGAP5 CHST3 ALDH7A1 LMNB2 COL5A2 DPH2 DTYMK DBN1 FZR1 IGHM KRT19 OLFML2B MAT1A DNASE1 CHPF	up	***
INAMURA_LUNG_CANCER_SCC_UP	0.0003720	0.0058397	0.4984931	0.8482458	1.880202	7	KRT5 SLC2A1 TPX2 TOP2A CDCA5	up	**
REACTOME_PURINERGIC_SIGNALING_IN_LEISHMANIASIS_INFECTION	0.0035537	0.0332931	0.4317077	-0.5413204	-1.879861	23	IL1A IL1B TXNIP ENTPD1 TXN MEFV CASP1 NFKB1	down	*
GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0000022	0.0000746	0.6272567	-0.3541657	-1.879853	180	CD300LF ST8SIA6 RDX GPR65 GIMAP8 HSD17B11 TMOD3 BACH1 GPCPD1 TET2 FAM49A RHOA B3GNT5 UBL3 MALAT1 GM2A ABCG1 CYB561A3 CLN5 SLC25A37 BTG3 EVI2B ITM2B KLF7 PLBD1 MGAT4A ELAC1 VIM EVI2A ADD1 AFF3 SNN TBC1D5 EMP3 MYLIP SGK1 KCTD12 RCAN1 CCR7 GPR183 FAM43A LPCAT2 KLF2 FOXO3 CD1D ATXN1 CD81 LGALS3 KYNU GPR18 SERINC3 CCR6 SELPLG CALHM2 ESYT1 CTSC FOXJ2 GIMAP4 RSU1 RNF13 ARHGEF18 FUS NCF1 KMT2E MAN1A1 MAP3K1 KLHDC1 TRIM25 CCPG1 JARID2 ST3GAL1 MFHAS1 ANXA6 RASSF5 MFSD8 CAPG DPP4 MYO1H ATP10D	down	***
GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN	0.0000016	0.0000565	0.6435518	0.4154035	1.879368	173	SLC2A1 MUC16 CDCA7 POLE DGCR8 KCNQ5 CDC6 MCM2 XPO5 NME1 NLE1 KNTC1 PUS7 POLD2 AKAP1 ENTPD6 TARS2 SLC12A7 FAM162A LIG1 ABCB6 PFKP CAD PPP5C IDH2 PARP1 PES1 THOP1 E2F1 DNA2 PDK1 SMO SF3B3 UQCC2 DNMT1 PUS1 AARSD1 MC1R HIRA TRIM37 C9orf152 GBP6 GEMIN5 PKP4 SND1 PFAS UBE2O KIAA0100 RRP9 GPATCH4 TBCA LPCAT4 HEATR1 EXOSC5 DPH5 HDLBP PRPF31 HK2 HLCS RDH10 MRPL21 OSGEP POLR1B RPN1 DTNBP1 TRUB1 SYNE2 CISH RASGRP1 FAM185A IMMP2L HEMK1 AVEN ISYNA1 SRM TIMM10 NDRG1 LRP8 MTHFD2 COX6A1 PFKL IPO4 ABCC1 PUSL1 SLC29A1 TXNRD3 RPSA RAD51B	up	***
GNF2_TYK2	0.0017926	0.0196706	0.4550599	-0.5072129	-1.879317	29	LRRFIP1 MANBA EIF1 LCP1 BNIP2 ARHGDIB ACTR2 NCKAP1L DDX5 MOB1A ADPGK PAK2	down	*
GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY	0.0001013	0.0019587	0.5384341	-0.4032372	-1.878635	81	SWAP70 DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 INPP5K BAG4 S1PR1 CDC42 RHOA RGCC SFRP1 SORBS3 ROCK2 SYNPO ROCK1 PLEK WASF2 SYNPO2 ARHGEF10 PTGER4 PIK3R1 PPM1F WNT11	down	**
GO_REGULATION_OF_SPROUTING_ANGIOGENESIS	0.0002601	0.0043108	0.4984931	-0.4169147	-1.878585	68	SEMA6A HMOX1 GATA2 BMPER TBXA2R MIR27B RHOA ANXA1 MIR146A MMRN2 ITGA5 AKT3 FOXC2 IL10 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A NOTCH1 JAK1 RHOJ	down	**
chr17q23	0.0006610	0.0092298	0.4772708	-0.4431502	-1.877983	50	TUBD1 SCN4A ACE PECAM1 NDUFB8P2 PPM1D TEX2 TBX2 C17orf82 TBX4 RNFT1	down	**
BIOCARTA_MCM_PATHWAY	0.0012987	0.0155787	0.4550599	0.6487290	1.877729	18	CDC6 MCM4 MCM2 ORC1 CDT1 MCM7 MCM3 ORC6 CCNE1 MCM6 MCM5	up	*
SEKI_INFLAMMATORY_RESPONSE_LPS_UP	0.0001226	0.0022903	0.5188481	-0.4133773	-1.877655	70	CXCL3 EREG ZMYND15 CXCL16 PTPRE BMP2 EGR2 CD44 CCRL2 FOSL1 SLC15A3 STX11 ABCB1 BIRC2 CCL3 MAFF BTG1 REL GSAP SOD2 ICAM1 RIPK2 RND1 NFKBIA ADAMTS7 JDP2 EGR1	down	**
FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN	0.0021822	0.0229719	0.4317077	-0.4691373	-1.877293	38	IL1B MIR22HG MKNK1 ANXA5 ITSN2 FLI1 PTPN12 HAUS2 LY96 CD53 BCLAF1 DDX5 USP7 CDC42EP3 EID1 ARFGAP3	down	*
GO_NEGATIVE_REGULATION_OF_SYSTEMIC_ARTERIAL_BLOOD_PRESSURE	0.0027664	0.0273050	0.4317077	-0.6444181	-1.877207	13	BMPR2 ADRB1 ADRB2 PRCP ADRA1A GPR37L1 SOD2	down	*
MORF_PHB	0.0000216	0.0005375	0.5756103	0.4402261	1.877096	106	DDX11 TOMM34 RBBP8 CIB1 WDR62 TP53BP1 BPHL TPR ERAL1 CDC25C PKMYT1 CAD FDXR PHB DYRK2 MEA1 PABPN1 RTCB DNAJC7 EIF6 FANCG ILF2 MLEC PSMD2 COPS6 SH2B1 TSTA3 CPSF4 SRRT MRPL28 TFAP4 AATF NUP62 MCRS1 NFRKB BMS1 RPRD2 CHD3 ADAM15 PWP1 PLIN3 ILVBL PRKAG1 XPO6 PCGF2 DRG1 NELFB TUBGCP2 MPST HMG20B SPRN CS PSMD3	up	***
GO_SPINDLE_ORGANIZATION	0.0000102	0.0002833	0.5933255	0.4210124	1.876235	146	CEP72 SPICE1 CHEK2 NEK2 CCNB1 NDC80 TTK RACGAP1 ASPM STIL MSTO1 PLK1 NUF2 AURKB ESPL1 TPX2 MYBL2 PRC1 DCTN2 HAUS5 WDR62 DLG1 KIF23 KIF3B AUNIP MAP10 AURKA TPR CENPW POC1A FSD1 KIF11 GPSM2 PSRC1 KNSTRN CEP97 BIRC5 KIF2A SPAG5 KPNB1 CEP63 CEP192 TUBG1 TACC3 CKAP5 CDC20 TUBG2 AAAS EFHC1 CHMP4C HAUS6 RCC1 HAUS4 NUP62 NTMT1 TUBGCP4 CHMP1A CHMP2A CHD3 CENPE GOLGA2 MAP9 CLASP1 DRG1 DYNC1H1 WRAP73 PCNT FBXO5 TUBGCP2	up	***
GNF2_PTPN6	0.0022115	0.0231661	0.4317077	-0.4685272	-1.874852	38	LRRFIP1 TXNIP DPEP2 EVI2B FAM49B LAPTM5 PTPRC SELL CD53 ARHGDIB EMP3 CD48 RAC2	down	*
REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES	0.0007821	0.0104981	0.4772708	0.5651110	1.874625	31	BRCA1 RBBP8 XRCC2 EXO1 EME1 EME2 RAD51AP1 BRIP1 BLM DNA2 RAD51D SLX4 RAD50 PALB2 RTEL1 RAD51 MUS81 SPIDR TOP3A RMI1 RMI2 RAD51B BARD1	up	*
GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP	0.0000008	0.0000326	0.6594444	-0.3538375	-1.874621	173	SIDT2 LPXN BAIAP2 ZCCHC2 IDI1 HMGCR NEDD9 ZBTB2 ENTPD1 NAAA RNF125 KLF10 SERPINB9 PDE4D ZYG11B RHOB TJP1 CLIC4 FMNL3 CCL3 DOCK9 COTL1 ATF3 CCL4 PNRC1 SMAD7 ELMSAN1 SH2D2A SERTAD2 RBPJ SOCS3 JUN ARL5B HPGDS PLK3 IFNGR1 PPP1R15A PTGER4 SKIL MALT1 TINF2 PIK3AP1 CD86 PDCD1 TOB1 PDE4B ETS2 AMD1 GEM SF1 HSP90AA1 TOB2 HAVCR2 MEX3C NUP98 TMEM184B NFKBIA GPR171 TRIM36 PMAIP1 SLC16A10 HERPUD1 EGR1 DUSP6 SLC38A2 ZFP36 DNAJB4 QSOX1 CYP51A1 DNAJB1 TSC22D2 FNDC3A NFIL3 SIRT1 CASP3 GZMB DUSP2 ZFP1 ADAM19 TNFRSF1B	down	***
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN	0.0000000	0.0000000	0.8390889	-0.3244466	-1.874353	392	HMOX1 MS4A7 FCN1 TSPAN4 PECAM1 SPN MNDA LTA4H RDX LY86 PLEKHF2 BACH1 CITED2 QKI MYD88 SLC39A8 APIP TBC1D2 MARCO NR3C1 PDE4C FUCA1 GAS6 TGFBR2 LILRB3 HEG1 GGA2 CCNL1 ZEB2 CD36 DPEP2 ATP2B1 ADA MALAT1 C1orf21 ECHDC1 MAP3K8 PARVG SPIRE1 CSGALNACT2 KLF10 KLF6 STOM LAIR1 C1orf162 RB1 CES1 APOC1 CD37 TIPARP IL10 CCDC82 SGTB KLF4 HAUS2 CTSD PDE8A RBMS1 TLR4 CD302 FRMD4A DUSP1 PINK1 CLIP4 VAMP5 RUFY3 AFF1 LACC1 PRCP KANK1 CREBRF SLC8A1 HESX1 SYNPO2 SGK1 SOCS3 MAML2 OASL LIMD1 KCTD12 HRH1 CELF1 HSPA1B DNASE2 WTAP PTGER4 SNX2 PTGER2 SUCNR1 OCIAD1 SIGLEC1 AGPS KLF2 MBP RIN2 PIK3AP1 SORT1 CCDC152 UBXN2A CHPT1 STXBP3 HNRNPA2B1 FPR2 ZC3H12D GNB4 PLA2G15 ARAP2 GPX3 IL18 PCM1 NBN SETDB2 SEMA4A CEBPD MS4A4A ACAP2 LRP12 CALCOCO2 GIMAP5 SP100 DDX59 METTL7A LYSMD3 CTSC FNIP2 B3GNT2 AIM2 LPAR6 SPATA13 DMXL2 ZFYVE26 SETX HIPK1 FUS NCF1 FPR1 ZFP36 PLEKHA2 SLC26A11 NFAM1 IFIT5 XRN2 CYP51A1	down	***
GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN	0.0000023	0.0000795	0.6272567	-0.3530969	-1.874179	180	CXCL3 EREG ACP5 IL1B MIR22HG ENG HEG1 GGA2 EIF4A1 ADA LMNA ANPEP RNASE1 PTX3 SLC7A11 LAIR1 SRSF2 FABP5 AHNAK HNRNPA3 ID3 DAB2 SLC7A8 VASP THBS1 CCL3 NFKB1 CCL4 ALOX5AP DNTTIP2 CD300C GNAQ IL7R TP53BP2 PI4K2A EMP3 RPS6KA2 SERTAD2 KANK1 TECR SAR1A OASL SERPINB8 SH3BP5 LTBP2 MAP4K4 PPP1R15A FERMT2 SNX2 PIK3R1 YWHAZ SLC3A2 CALM1 TIMP2 EWSR1 APLP2 LGALS3 PLEKHO2 CPQ ARRB2 TOB2 TRAF1 TMEM184B S100A4 DOCK10 DLST	down	***
WAMUNYOKOLI_OVARIAN_CANCER_LMP_DN	0.0000008	0.0000329	0.6594444	-0.3536977	-1.873880	173	MNDA CAV1 PRKAR1A RCHY1 TMX4 ATP2B1 WNT2B MAP3K8 CSGALNACT2 SIRPA ZYG11B KPNA5 PTPN12 PTPN21 BNIP2 PPM1K CPVL RUNX1T1 PLEKHM3 DAB2 SOCS5 FBXL3 SPAG9 RBMS1 UBE2E2 WASF3 GCA DSE CLIP4 CALM2 TGFB2 PROCR ZNF330 SH3BP5 GABPA CCDC50 OSTM1 FERMT2 DDX5 TSPYL1 EPC2 RNF146 CELF2 BLOC1S6 PKD2 FLNC HNRNPD TCF4 PLSCR4 SOD2 SBSPON SPOCK2 KAT2B EPB41L5 TIAM1 POLR2M TTC28 TIMP3 MAGI2-AS3 KIF1B FAM13B ZFPM2 WDFY3 REEP1 PSIP1 CDON CFL2 MYH10 CBR4 PTGS1	down	***
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP	0.0001926	0.0033298	0.5188481	-0.4049470	-1.873765	76	CD52 FCN1 LY86 CD8A ENTPD1 IFI30 LCP1 APOC1 FABP5 CFD LAPTM5 RBMS1 PTPRC CD53 FCER1G CD48 RAB31 RAC2 TYROBP CSTA GLIPR1 GMFG RASSF2 CELF2 CXCR4 IFFO1 S100A4 GLUL CCND3 C1QB AOAH S100A8	down	**
GO_POSITIVE_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0038169	0.0350292	0.4317077	-0.5395622	-1.873755	23	HMOX1 GATA2 MIR27B ANXA1 MIR146A AKT3 FOXC2 PIK3C2A RHOJ MIR23A FGF2	down	*
GO_MITOTIC_DNA_REPLICATION_CHECKPOINT	0.0014400	0.0167036	0.4550599	0.7616043	1.873660	10	TICRR CDC6 ORC1 CLSPN TOPBP1	up	*
REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE	0.0007070	0.0097128	0.4772708	0.6203623	1.873526	22	HJURP RUVBL1 CENPA MIS18A CENPL CENPW CENPO CENPH CENPP CENPQ CENPK CENPM CENPT	up	**
GSE3920_UNTREATED_VS_IFNA_TREATED_FIBROBLAST_UP	0.0000031	0.0001014	0.6272567	-0.3575413	-1.873075	157	SIDT2 BAIAP2 SLC15A3 NR3C1 GNPTAB CCNL1 SH2B3 PPP2R2A RGCC CLK1 ADARB1 CSRNP1 FOXO1 ZSWIM6 MAFG SPAG9 CCL3 NFKB1 ZBTB43 CLK4 FXYD7 SH2D2A BTG1 NINJ1 RNF149 ETV3 ARL5B PLK3 EPC1 DUSP8 CD83 PTGER2 MIR23B TNFRSF10B TINF2 PIM1 CLDND2 GABARAPL1 ICAM1 ABL2 USPL1 SIK3 BRWD1 TRAF1 ADORA2A JMJD1C TTC19 RORA MT2A ZFAND2A ATF4 RABGEF1 HERPUD1 CCNK CD69 SLC25A19 ZBTB46 FNIP1 NR4A3 HIVEP1 AKAP13 NFKBIZ DUSP2 FEM1C KANSL3 RASA2 ANKRD17 ITK BCL2L11 ABTB2 PPP1R16B SESN2 RARA ATG16L2 NFAT5 VPS37B RELB ELL2 TNFAIP3 DNAJB2 CMIP PAN3	down	***
SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP	0.0000000	0.0000010	0.7337620	0.3939851	1.873059	281	SLCO5A1 HELLS PARPBP FANCI BUB1B ZNF84 CENPF FLVCR1 PBK KIF18B COL27A1 TTF2 NDC80 DEPDC1B CDCA7 TTK GINS1 C6orf141 RACGAP1 ANLN NUF2 ECT2 SFXN1 E2F3 FIGNL1 ANKRD22 RBBP8 FCGR3B UHRF1 MCM4 TYMS FERMT1 PRC1 CCNF DTL CCT6A MCM8 ZWINT CXCL10 MELK KIF23 CEP55 KIF15 TOP2A DPY19L1 CBX3 VASH2 MPHOSPH9 RRM2 PRKDC WDHD1 HOXC6 KIF11 SOX4 CHEK1 DNAJC9 MAD2L1 RAD51AP1 DSCC1 BRIP1 CXCL9 CXCL11 NUSAP1 CDK1 POLE2 CENPJ ZNF260 GMNN UNG NCAPG VANGL2 DNA2 COL3A1 SSX2IP EZH2 DIAPH3 ARNT2 COL1A1 COL1A2 DLGAP5	up	***
SCIAN_INVERSED_TARGETS_OF_TP53_AND_TP73_DN	0.0031078	0.0299364	0.4317077	-0.5143857	-1.872118	27	BAIAP2 EIF1 HNRNPA3 KLF9 ATF3 BTG1 ETF1 CELF1 DDX17	down	*
GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	0.0000056	0.0001719	0.6105269	0.4121573	1.871533	177	RUVBL1 CDC45 TICRR MCM10 TIMELESS POLQ BRCA1 ASPM AURKB EBF3 MCM2 CCNF EIF3B MCM8 MIS18A NCAPD2 CCDC150 CHAF1A TRIM29 KNTC1 POLA2 COASY TTLL12 CDCA5 DNAJC9 TIMM50 DSCC1 BLM PSRC1 NCAPG2 NUSAP1 MRPL37 SERTAD4 CENPJ ATIC RBCK1 UNG FEN1 EZH2 SPAG5 SF3B3 RECQL4 KPNB1 POLR2H SNRNP25 MRPS34 UBE3D DOK4 DTYMK TJAP1 ANAPC1 NUP85 RBM33 CPSF4 CDC20 LRRC59 MGME1 MCM5 MALSU1 DDX23 SLC1A5 STK39 CORO2A PMS1 GLO1 PRR11 CISD3 CCDC167 WDR4	up	***
GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN	0.0000026	0.0000864	0.6272567	-0.3530339	-1.871271	181	KLF13 ZC3H12C EGR2 FOSL1 HMGCR VAPA MOB1B IER2 SLC7A7 EIF1 PPP2R2A GATA3 NR4A1 SRGN BTG3 ATP6V1H IL10 MAP2K3 ROCK2 STAT5A SDCBP RNFT1 RMDN3 NFKB1 ATF3 CCL4 CCND2 SH2D2A ACTG2 BTG1 ETF1 METAP1 RNF149 IL6 NOTCH1 KCTD12 ST6GALNAC4 FYTTD1 IRF8 HSD17B12 AGFG1 FOS RHOQ PELI1 MSMO1 DDX18 PDCD1 GABARAPL1 CCR1 MAGOH CSNK2A2 RXRA FKBP1A CUL3 BCAT1 NFKBIA B3GNT2 GIMAP4 PIM3 EGR1 TNFSF8 DUSP6 FIP1L1 CENPC AQR BCL10 SLC25A19 IL5 TES FNDC3A SRXN1 TTC39B DUSP2 OTUD7B ARID3B GGNBP2 MTDH AGO2 DNAJB6 ZNF281 MAPK6 IQGAP2 PTPN1 ZC3H14 NFATC1 ZC3H11A CINP EIF2S1 NCOA3	down	***
BAELDE_DIABETIC_NEPHROPATHY_UP	0.0001331	0.0024486	0.5188481	-0.4119479	-1.871163	70	SEMA6A ACVRL1 TEK PECAM1 CLEC3B FBP1 TIE1 RAMP2 PTPRB ENG ARHGEF15 INPP5K EML1 FXYD2 GAS6 SLCO2A1 PDE2A PTPRM ZCCHC24 CCL3 PTGIS ADAMTSL2 VAT1 GAS2L1 PPM1F CD34 ICAM2	down	**
GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN	0.0000042	0.0001352	0.6105269	0.4148655	1.871135	168	RIBC2 CCDC34 CENPF GGCT SORD FGF11 EFNA4 UMPS PRC1 CCNF ACY1 KHDC1 C5orf34 RUVBL2 BZW2 EXO1 TP53BP1 PCCB WDR3 SYNE4 WDHD1 SDHAP1 KDELR2 BRIP1 FNTB INPP4B IDH2 CKLF MRPL37 CENPJ UCK2 WDR54 SMG9 TRAP1 KIF2A LRRC42 OARD1 ETFB MAD2L2 RECQL4 SNRNP25 PARS2 DNAJC17 FAH DNAJA3 HDAC1 ANP32E ATAD5 PARP9 NIF3L1 SASS6 NFXL1 FAF1 FAHD1 ROMO1 TDP1 HMCES LSM4 ZNF780A CEP152 RRNAD1 DCPS VDAC1 MICU1 CHMP2A PAICS PPP1R14B HEMK1 CORO1B ALKBH2 CYB5B C9orf40 BCKDK	up	***
GO_HEART_GROWTH	0.0001108	0.0021072	0.5384341	-0.4015303	-1.870399	78	RBP4 CCM2L S1PR1 PRKAR1A TGFBR3 TGFBR2 HEG1 TBX2 FOXC2 MIR24-2 TBX5 MIR17HG TGFB2 RBPJ NOTCH1 ADRA1A SAV1 MIR23A PIM1 MEIS1 GATA6 RGS2 RXRA FGF2 PDLIM5 ACACB EDN1 PTEN FGFR1 MIR548C ZFPM2 DUSP6 MAPK1 NOG	down	**
REACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE	0.0001057	0.0020298	0.5384341	0.4492513	1.870304	87	CEP72 CEP89 RPGRIP1L NEK2 RAB3IP MKS1 CEP70 PLK1 DCTN2 HAUS5 CEP250 FBF1 ODF2 SFI1 C2CD3 IQCB1 CDK1 CEP97 CENPJ TCTN2 FGFR1OP CEP63 CEP192 NPHP1 TUBG1 NINL CKAP5 TCTN1 CDK5RAP2 HAUS6 HAUS4 CEP152 B9D1 ALMS1 CEP164 MARK4 CLASP1 KIF24 CEP290 DYNC1H1 PLK4 AKAP9 PCNT	up	**
GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP	0.0000063	0.0001875	0.6105269	0.4121478	1.870153	176	TRIP13 ELOVL6 CHEK2 NEK2 PSPH TTK RACGAP1 ANLN ASPM CDCA8 PTTG1 CDC6 CCNB2 EIF3B DTL CDT1 NUDT1 CISD1 MKI67 BUB1 TOP2A AURKA POLD2 MCM7 CPD RGL1 CDCA5 PDCD5 MRPL27 KIF11 LMNB1 LIG1 KDELR2 CHEK1 ORC6 MAD2L1 BLM CKS1B DRC1 NUSAP1 CBX5 ASF1B CDK1 UCK2 BIRC5 POLR3K SEC61G SSX2IP NRGN DLGAP5 TACC3 DTYMK ZNF239 GEMIN5 CENPK SASS6 DHRS1 PSMB3 CDC20 MRPL41 MRPL51 NEDD8 MARCKS UNC119B RPS26 DCPS ECH1 MIEN1 RFC5 PRPF31 SEC13	up	***
GO_NUCLEAR_REPLICATION_FORK	0.0008316	0.0110182	0.4772708	0.5310448	1.869729	38	CDC45 MCM10 TIMELESS PRIM2 GINS4 POLA2 POLD2 SMARCAL1 MMS22L WDHD1 HELB MCM3 ZMIZ2 GINS2 POLD1 RPA1 ZRANB3 PRIM1 TONSL PRPF19 ETAA1 TIPIN POLD3 CDC5L	up	*
GSE22886_DC_VS_MONOCYTE_DN	0.0000025	0.0000832	0.6272567	-0.3562140	-1.869514	167	FCN1 KLF13 CD55 U2AF1 PTP4A2 PID1 FYN HSD17B11 KIAA1109 INPP5A NEDD9 AGTPBP1 SLC11A1 LILRB3 IER2 SLC7A7 KLF6 CD93 TCF7L2 MCL1 CD37 GMEB1 MAP2K3 CFD CASP1 KLF4 P2RY2 SELL HPSE DUSP1 ELK3 GCA BTG1 CD48 CSTA FOS PELI1 KLF2 ICAM2 FAM204A ING3 CD1D IRS2 N4BP2L2 RGS2 CDC42EP3 CEBPD SIK3 SP100 MEGF9 CREBBP LYST THEMIS2 PMAIP1 DUSP6 CX3CR1 ING1 ITGAL FPR1 ZFP36	down	***
LIAO_METASTASIS	0.0000000	0.0000000	0.8390889	0.3796170	1.869096	462	DKK1 TRIP13 HKDC1 PTGES FOXM1 SLC29A4 HJURP BUB1B SLFN13 HOXD8 SULT1C2 UCHL1 IGF2BP3 CIB2 KIF18B TSHZ2 GCNT3 SLC2A1 TOX3 DDIT4 THEM4 CDCA7 ZP3 GTSE1 NPAS2 BAMBI NUF2 ALDH18A1 ECT2 SOX9 RAD54B MYBL2 CA12 FERMT1 HPS3 SPINK1 TMCC1 NUB1 PPP1R9A TTLL4 RUVBL2 ITGA2 KCNH2 IGF2BP2 PAFAH1B3 VANGL1 MPHOSPH9 ANKRD52 RAD54L PKM FHOD3 SOX4 BRD9 PLXNA1 MORC2 PDZK1IP1 ZNF618 SPINT1 SCAMP5 CCL28 GNPDA1 PTGFRN SNAPC4 NOL3 ALDOA DLG5 DHRS13 PES1 GPX8 PPIL2 CBX5 DMKN BCAS4 BIRC5 WDR54 ATIC E2F1 FBXO41 KIF2A NEIL3 ZNF789 PDK1 EZH2 USP42 SLC44A3 TRAF5 IGSF3 ZNF827 DENND1A SUSD4 ITPR3 TPD52L2 WFIKKN1 GRAMD1A CCNE1 ST14 DPP3 COL1A1 COL1A2 SMG5 TACC3 EFCAB2 SNRPA TUBB2A MAPK13 TMEM237 ZNF234 DTYMK DBN1 ENAH CHTF18 ZNF239 SCN8A HDAC1 MSI2 PKP4 ASNS CDK13 FXYD3 CLTB CDC7 SH2B1 TSTA3 UBE2O CENPM PLD1 TWIST1 ZCCHC17 HMGA1 ASRGL1 ZNF432 GNG4 SURF2 ZNF783 TMCO4 MYEF2 PFKFB4 PDIA4 RHOBTB1 STK39 ZNF765 SF3A2 ATAD2 ARFGAP1 STRBP SPAG4 CKAP4 INTS8 SPON2 LRP11 PRR11 DENR CEP164 PCSK5 PRPF31 CAPN10 ZNF292 SLC25A29 MROH1 ZMYND19 GBP2 IKZF4 TMED9 LLGL1 UBAP2L PNKP TCF3 DTNBP1 FBLIM1 ROBO1 DNAJC10 KIAA1522 SLC36A1 ANKRD46 RASA4 DNM1L RABL6 TMEM201	up	***
GO_NEGATIVE_REGULATION_OF_INTERLEUKIN_8_PRODUCTION	0.0047593	0.0411156	0.4070179	-0.6041186	-1.869074	16	ANXA1 MIR146A CD33 IL10 ARRB1 KLF4	down	*
GO_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.0009742	0.0124689	0.4772708	-0.4378714	-1.868868	51	CD55 TGFBR2 IL23A ANXA1 HLX GATA3 SOCS5 SMAD7 NCKAP1L CD80 CD160 CD83 MALT1 RC3H1 TBX21 RUNX3 CD86 CD81 IL18 RIPK2 NLRP3	down	*
GRADE_COLON_AND_RECTAL_CANCER_UP	0.0000003	0.0000121	0.6749629	0.3964051	1.868776	247	HELLS HJURP CDC45 ZMYND8 PDCD6 ZNF84 CCNB1 TIMELESS POLQ PDCD2L THOC3 DDIT4 CDCA7 HILPDA SPP1 PLK1 CDC6 SOX9 MCM4 MCM2 FERMT1 EIF3B LDHB MELK KIF23 KNTC1 PAFAH1B3 EEF1E1 CCT5 DPY19L1 BPHL AURKA POLD2 MCM7 ICA1 RRM2 PRKDC MRPL3 PKM GPSM2 MCM3 AHCY PSMD4 FBL BACE2 PERP HOXB5 NUSAP1 URI1 CDK1 DNTTIP1 ATIC TRAP1 DGAT2 MRPL17 METTL3 TRAF5 LAPTM4B PA2G4 EIF6 EFTUD2 CHCHD2 VBP1 ACBD6 INTS7 POFUT1 MRGBP DNAJA3 EPHB2 SSRP1 DAP3 AAMP CCT7 ETV4 GEMIN6 PSMB3 METTL2B DHX8 NOB1 MCM5 SRSF1 RTKN RCC1 GTPBP10 GLO1 RFC5 CARHSP1 MRPL9 SLC12A2 SMPD4 ALG1 MTHFD1 SEPHS1 PPIA CDC25B SH3GL1 TRUB2 AZGP1 TFB1M CSTF1	up	***
MIR4740_5P	0.0001678	0.0029646	0.5188481	0.4803781	1.868443	59	PCDHGA10 ELOVL6 ZNF84 PCDHGA9 PCDHGA5 PCDHGA7 SLC25A21 PCDHGA1 PCDHGB3 P2RX2 PCDHGA11 PCDHGA8 PCDHGA12 PCDHGB7 PCDHGA3 URI1 PCDHGA2 PSMA5 KCNIP3 ACLY RER1 GLO1	up	**
GO_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.0000000	0.0000000	0.9214260	-0.3075462	-1.868248	578	SIRPB1 SLPI FOXF1 HMOX1 SWAP70 FCN1 OLR1 PECAM1 HVCN1 CD55 GAPT GATA2 SPN MNDA LTA4H CAT RAB44 CLEC12A PTPRB OSCAR CD44 PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA CD1C VAPA FUCA1 LAMP1 CBL SLC11A1 LILRB3 IL23A FGR RHOA DNASE1L3 CD36 ANXA1 SLC44A2 CLCF1 DNAJC3 MAN2B1 ADA CD33 ARSB ASAH1 RAP1A GM2A FOXP1 ANPEP PTX3 HLX LCP1 IFNK STOM LAIR1 GATA3 SIRPA IL18R1 CD93 GRN LAMTOR3 TFRC RAB14 CD58 CST3 IL10 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D SOCS5 CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE TLR4 ARHGAP9 CD53 FCER1G SMAD7 GCA DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP CD80 IL6 CTSS PSEN1 SNAP23 VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG PTGER4 ENPP4 GLIPR1 GMFG PRKCE GPR183 MALT1 RC3H1 SERPINB6 CAP1 SUCNR1 TBX21 ZNF683 PLCG2 TNFSF13 PSMD12 ALDH3B1 TREX1 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 TGFB1 AP1G1 DOK3 MILR1 SERPINB1 FPR2 TSPAN14 CD86 DYNC1LI1 ATP6V0C GPR84 CD81 LGALS3 ORM2 BRI3 MFNG PLEKHO2 ADAM10 IST1 COMMD9 UNC13D CCR6 ICAM1 IL18 LAT NBN SEMA4A HSP90AA1 RIPK2 NLRP3 HSPA8 HAVCR2 METTL7A CD19 NHLRC3 KIT SIGLEC9 CTSC DOCK10 ARPC5 SNAP29 P2RX1 RORA PSMD6 IQGAP1 CREG1	down	***
REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	0.0000851	0.0016828	0.5384341	-0.4004400	-1.868121	79	RAMP3 GPR15 LHCGR ADCY9 ADCY4 RAMP2 CALCRL ADCYAP1R1 PRKAR1A RXFP1 GNGT2 ADRB1 GNG7 ADRB2 GPBAR1 PTGIR GNAI2 PTH1R ADCY2 IL6 PTGER4 CREB1 PTGER2 PRKACA GNAI1 GNG5 GPR84 GNB4	down	**
GO_NON_RECOMBINATIONAL_REPAIR	0.0003722	0.0058397	0.4984931	0.4741997	1.868089	61	HMGA2 POLQ BRCA1 RBBP8 LIG3 TP53BP1 POLM AUNIP PRKDC XRCC1 MAD2L2 DCLRE1C POLL POLB PARP9 SLX4 RAD50 UBE2V2 XRCC4 UIMC1 DTX3L PAXIP1 NUDT16L1 PIAS4 PRPF19 RNF8 DCLRE1B DCLRE1A HERC2 XRCC5 XRCC6 BARD1 REXO4 ERCC8	up	**
MODULE_262	0.0012981	0.0155786	0.4550599	0.6939784	1.867887	14	LTF TF CCL19 CP	up	*
GO_RETINA_HOMEOSTASIS	0.0006438	0.0090437	0.4772708	0.5085444	1.867686	45	LTF TF MDM1 ZG16B PROM1 CIB2 BBS1 CNGB1 IQCB1 CROCC CDH3 POC1B LCA5 ABCA4	up	**
LE_EGR2_TARGETS_DN	0.0001143	0.0021582	0.5384341	-0.3875746	-1.867510	93	PRX CD55 CPEB2 CAT EMP2 LPL IDI1 HMGCR MAL CD9 ABCB1 SEMA3B RGCC MAPK8IP1 TIPARP CLDN5 MYO1B CDKN1A RAP1GDS1 MYH11 CMTM6 UTRN PIK3R1 MBP MSMO1 PEA15 GNAI1 ADAM10 SCN7A RTN1 LIMCH1 FDFT1 IL16 RNF13 PIM3 ZBTB16 TMEM30A HMGCS1 NR4A2	down	**
GO_MITOTIC_SPINDLE	0.0000920	0.0018016	0.5384341	0.4405982	1.866718	99	PKHD1 KIF18B RACGAP1 ASPM AURKB ECT2 ESPL1 TPX2 TFDP2 KIF23 MAP10 AURKA TPR MAD1L1 DCDC2 KIF11 GPSM2 YEATS2 MAD2L1 CKAP2L KNSTRN NUSAP1 IQCB1 CDK1 SPAG5 KLHL22 RANGAP1 TACC3 KIF22 PKP4 KIF20B CDC7 TADA3 AAAS EFHC1 CDK5RAP2 FAM161A NUP62 AGBL5 CTTN CENPE GOLGA2 DCDC1 MAP9	up	**
GO_PROTEIN_LOCALIZATION_TO_KINETOCHORE	0.0020196	0.0215940	0.4317077	0.6815299	1.866391	15	NDC80 TTK AURKB CDT1 SPDL1 CDK1 TRAPPC12 MTBP CENPQ	up	*
GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP	0.0000012	0.0000457	0.6435518	-0.3505915	-1.865899	177	MCOLN1 MIR22HG TRPV2 SMIM12 FLVCR2 GAS6 LAMP1 TRIB1 HEG1 CD36 RRAGC C1orf21 BTG2 TNIP3 ZNF410 HIPK3 HLX SERPINB9 STOM LAIR1 CRK PDGFA CASP5 RHOB COQ10B DRAM1 CDK9 MAFG RBMS1 FRMD4A CD53 DSE IL7R DCHS1 KREMEN1 SPIN1 SLC8A1 VPS37A CREM SOCS3 SLCO2B1 PLEKHA3 LRCH1 CPEB4 HK3 HRH1 VPS26A AGFG1 SNX9 PIK3AP1 JMJD6 KCTD10 FPR2 PIM1 GNA13 RIMKLB GPR18 SERTAD1 DCTN4 MS4A4A PLGRKT KATNA1 GRB10 NABP1 PSMD9 WDFY3 PUS3 SLC16A10	down	***
GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN	0.0000022	0.0000755	0.6272567	0.4124157	1.865851	173	TRIP13 KLC3 HELLS MCM10 NDC80 POLE CDCA8 ECT2 CDC6 E2F3 MCM4 RUNDC3A MCM8 MELK EXO1 TP53BP1 KNTC1 TOP2A IFI44L CENPW CLSPN WDR78 RRM2 MMS22L CDCA5 AKAP1 RAD54L SOX4 SALL2 LIG1 CHEK1 MAD2L1 CKAP2L DSCC1 PTGFRN BLM PML CKS1B NCAPG2 PLOD2 ASF1B PAK1 CDK1 BIRC5 GMNN E2F1 EZH2 CNOT11 RTP4 CENPP HSPA4L IFI27L2 ATP9A LMF1 TK1 ATAD5 PARP9 CENPK GTF3C1 CENPM DNMT3A MCM5 ALMS1 PRR11 SHCBP1 ZWILCH SMC2 ENTPD7 ADCY6 RNF213 SMPD4 CHL1	up	***
GSE3982_BASOPHIL_VS_TH1_DN	0.0000023	0.0000797	0.6272567	0.4125164	1.865799	171	HELLS ELOVL6 CHEK2 BUB1B NEK2 GGCT DDIT4 NUDCD3 TTC26 ALDH18A1 XRCC2 GLB1L2 MIS18A NME1 IKBKE RANBP1 SYTL2 AURKA SFI1 RSRC1 GCAT CHAF1B MORC2 CHEK1 DNAJC9 CC2D1A OGFOD2 BLM MTG1 PHB SPRY1 TMED3 PSMB5 CCNJL SPAG5 HMGXB3 PSMC4 UBFD1 TUBG1 DHODH MRPL11 DPH2 MRPL4 LRRC20 SCNN1G LIMA1 HMGA1 RRP9 CDR2 RAI14 STK39 CBR1 TCERG1 PRMT5 MSH2 SLC2A5 DCPS DOHH ABCF2 ELOVL4 RAD51 ZWILCH PPFIA3 ADRM1 CHL1 MTHFD1 PAICS ENO1 WIZ RANGRF NQO1 MLLT11 MRTO4 SHQ1 PRPF19 RWDD2B TOMM40 RPS6KB2 NETO2 STXBP1 MRC2	up	***
GO_POSITIVE_REGULATION_OF_B_CELL_PROLIFERATION	0.0015874	0.0179896	0.4550599	-0.4855682	-1.865083	35	CLCF1 ADA WNT3A TFRC BST1 CDKN1A PTPRC TLR4 NCKAP1L GPR183 PELI1 CD74 VAV3 IRS2 CD81	down	*
GO_NEGATIVE_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION	0.0052169	0.0441398	0.4070179	-0.7013574	-1.864607	10	GTF2I ATP2B1 KCNK3 KCNA5 SLC8A1	down	*
JAEGER_METASTASIS_DN	0.0000009	0.0000331	0.6594444	0.4038346	1.864505	200	COL17A1 LTF ALDH3B2 GPR87 PTPRZ1 TP63 BBOX1 KRT5 LAD1 FAT2 S100A2 PKP1 SLC2A1 ABCA12 COL7A1 KRT16 AKR1C1 DIO2 PAK6 SPINT2 LSR CA12 FERMT1 KRT15 AP1G2 GPX2 MAP7 LAMC2 F2RL1 STAP2 TRIM29 ITGB4 FLG TMEM45A FHOD3 EGFR CD24 PDZK1IP1 ASS1 MST1R PERP EHF GRHL2 LTB4R CXCL14 RAPGEFL1 GJB3 CDH3 SRD5A1 ITPR3 IRF6 NET1 LGR5 ST14 ARHGAP32 PKP3 MAPK13 S100A9 KRT19 ELMO3 FXYD3 ENPP2 CLTB	up	***
GO_HISTONE_EXCHANGE	0.0006986	0.0096236	0.4772708	0.5371830	1.864406	36	HJURP RUVBL1 CENPA MIS18A CENPL CENPW ZNHIT1 CENPO CENPH VPS72 CENPP CENPQ ANP32E CHD5 CENPK CENPM CENPT	up	**
GO_CELLULAR_DEFENSE_RESPONSE	0.0024458	0.0249774	0.4317077	-0.4657951	-1.863919	38	SPN MNDA FOSL1 C5AR1 NCF2 LY96 PRF1 CD300C TYROBP KLRC2 CCR6 CCR9 ADORA2A CX3CR1 ITGB1 NCF1 BCL10 TRAT1 KLRG1 ITK LSP1 CCR5 VEZF1 LGALS3BP	down	*
REACTOME_TYPE_I_HEMIDESMOSOME_ASSEMBLY	0.0009246	0.0119588	0.4772708	0.7870575	1.863786	9	COL17A1 KRT5 LAMC2 ITGB4	up	*
SCHOEN_NFKB_SIGNALING	0.0019706	0.0211973	0.4317077	-0.4981119	-1.863556	31	IL1A HHEX IL1B PTX3 CSRNP1 KLF4 THBS1 CXCL2 CTSS PTGER4 TNFRSF9 NFKBIA EDN1 CSF2 CDKN1B	down	*
GO_METAPHASE_PLATE_CONGRESSION	0.0006261	0.0088396	0.4772708	0.4910634	1.863460	53	SPICE1 CCNB1 CENPF NDC80 KIF14 NUF2 CDCA8 CDT1 SPDL1 BOD1 KIF2C MAD1L1 CDCA5 PSRC1 SPAG5 TRAPPC12 KPNB1 CDC23 KIF22 CENPQ CHMP4C NUP62 CHMP1A CHMP2A CENPE RRS1 CHMP6 DYNC1H1	up	**
GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP	0.0000034	0.0001114	0.6272567	-0.3540962	-1.863179	168	CXCL3 IL1A GLIPR2 CPEB2 IL1B RAPGEF2 HCAR2 CCRL2 GFOD1 RASAL2 SLC15A3 STX11 ALAS1 IL1RL1 IL1RN TET2 TNIP3 MAP3K8 PICALM HDC FOXP1 SLC7A11 SLC25A37 IL10 UHRF1BP1L CLIC4 CCL3 NFKB1 CXCL2 C9orf72 CCL4 DUSP1 PLEK OXSR1 IL7R PIK3R5 HTRA4 PROCR FMNL2 RNF149 IL6 SOCS3 INPP5B OASL TREM1 ELOVL7 MALT1 TNFRSF9 PTP4A1 HIVEP2 RIN2 SMPDL3B PIM1 SOD2 STK40 GNA13 PDE4B IER5 RIPK2 RND1 NFKBIA EDN1 MCOLN2 TNFSF9 SAMSN1 NRG1 MT2A	down	***
PID_BCR_5PATHWAY	0.0007276	0.0099062	0.4772708	-0.4248249	-1.862347	57	BCL2A1 CD22 PAG1 PPP3CA TRAF6 PPP3CC NFKB1 PTPRC JUN SH3BP5 ETS1 PIK3R1 GRB2 MALT1 PLCG2 FOS MAPK8 CD19 NFKBIA PTEN MAPK1 CD79B DAPP1 BCL10 MAP3K1	down	**
GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN	0.0000014	0.0000524	0.6435518	-0.3499166	-1.862308	177	CXCL3 IL1B SNX10 LPXN FIG4 C5AR1 CD9 IL1RN AGPAT4 CD5 LIFR RAP1A EMILIN2 LITAF HDC HIPK3 SIRPA TIPARP PTPN12 TBC1D9 DUSP3 AGO3 COQ10B TMED5 PDE8A ERP44 VIM ID2 DUSP1 AKIRIN1 RAB6A CD80 SNAP23 PLEKHA3 JUN RAB31 CTSZ PTGER4 STX7 PSTPIP2 PRKCG EMC7 AZIN1 NIPA2 ZC3H12D PIM1 ATXN1 ADPGK GEM YAF2 SLC31A1 NLRP3 ALDH2 MCOLN2 NRP2 NR3C2 NABP1 CSF2RB CLEC4E SLC38A2 FXYD5 MTSS1 NFIL3 ATF6 RC3H2 ECHDC3 CLVS1 PTGS2 ST3GAL1 CYTIP PSMD14 RNPS1 SCAMP1 NOP58 FGL2 ZNF281 PTPN1 BCAP29 S100A10 CCR5 EIF2S1 RILPL2	down	***
GO_DYNEIN_COMPLEX	0.0006530	0.0091441	0.4772708	0.5028321	1.861450	47	DNAH2 NUDCD3 DNAH3 DYNC1I1 DNAH14 DCTN2 DNAI1 TPR WDR78 CCDC114 WDR60 DNAH8 DNAH11 DRC1 DNAH6 SNX4 DYNLL2 DNAH5 DNAH7 WDR34 DYNC1LI2 DNAI2 DYNC2H1 DNAH1 DNAL4 DYNC1H1 WDR63 DYNLT1 CCDC65 DNAH9 DNAL1 DNAH12 TCTEX1D2 DNAH10	up	**
GO_CALCITONIN_FAMILY_RECEPTOR_ACTIVITY	0.0014437	0.0167233	0.4550599	-0.8713407	-1.860281	5	RAMP3 RAMP2 CALCRL	down	*
BENPORATH_CYCLING_GENES	0.0000000	0.0000000	0.8986712	0.3726025	1.860141	569	MNX1 TRIP13 DDX11 FOXM1 ABCC2 HELLS MDM1 HJURP CDC45 FANCI TROAP TFAP2A CHEK2 BUB1B NEK2 CCNB1 CENPF POLQ UBE2T MND1 PBK TTF2 NDC80 PRIM2 PIF1 BRCA1 TFF3 DEPDC1B CDCA7 TTK E2F8 GTSE1 KIF14 ANLN CCDC14 TRAIP STIL COL7A1 FLAD1 TOMM34 CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 RBBP8 UHRF1 MCM4 MCM2 TYMS CDC25A PRC1 ORC1 CCNF DTL MCM8 ASPHD2 MAP2K6 RCCD1 NCAPD2 ZWINT SPDL1 TRIM45 HAUS5 WDR62 MELK HMMR EXO1 KIF23 CEP55 STAG3 CHAF1A MKI67 RHNO1 BUB1 FANCA TOP2A IDO1 CENPL AURKA CBX3 VANGL1 ODF2 TMEM132A KIF2C C6 POC1A CLSPN RRM2 RHOBTB3 RAD54L KIF11 PASK FANCD2 GPSM2 CHAF1B HORMAD1 LMNB1 CDC25C CD24 CDC42EP1 TOPBP1 MAD2L1 RAD51AP1 MDM2 TRMT2A DSCC1 CAPS PKMYT1 RAD18 ZNF587 DET1 KNSTRN CKS1B CDKN2C CXCL14 HPS4 NUSAP1 ASF1B RNPC3 BIRC5 AP3D1 GMNN GOLGA8A E2F1 UNG DNA2 MRPS2 LARP1 NEIL3 FEN1 PSMG3 SPAG5 TNPO2 FADD VPS72 RECQL4 SRD5A1 ITPR3 KPNB1 RANGAP1 FANCG INTS7 ILF2 CCNE1 DLGAP5 TACC3 MBD4 TUBB2A KIF22 MAPK13 USB1 CENPQ GINS2 FZR1 ANP32E KIF20B ENOSF1 SAP30 CDC7 CKAP5 BRD8 VPS25 CDC20 CENPM EFHC1 AP3M2 CDR2 ABCA7 MCM6 CKAP2 DHX8 MCM5 LRRC17	up	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_UP	0.0000030	0.0000993	0.6272567	-0.3543723	-1.859848	167	IL1A USP12 OTUD1 NEDD4L AQP9 SFR1 BCL2A1 AGPAT4 SCARF1 RFTN1 SLC7A7 MTF1 TNIP3 PTX3 SLC25A37 AKT3 EIF1B IL10 TBC1D9 TNFSF15 SOCS2 SEC24B PDE8A P2RY2 ZBTB43 UBE2B HES1 TP53BP2 KANK1 FLT1 IL6 SOCS3 MAML2 STAT4 HRH1 WTAP ELOVL7 FERMT2 ENPP4 PNPLA8 SIGLEC15 FSD1L TNFRSF9 GFPT2 AGFG1 PIK3AP1 AZIN1 SAV1 EHD1 SERPINB1 FPR2 PIM1 ETS2 MIR155HG IER5 CDC42EP3 PLGRKT MAP3K4 BCAT1 NFKBIA RASSF8 PTEN MCOLN2 TRIM36 PAPSS2 SLC16A10 FJX1 SVIL DCUN1D3 OSGIN2 MSANTD3 YRDC HEY1 CCDC93 GPR137B	down	***
GO_POSITIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_INVOLVED_IN_ENDOCARDIAL_CUSHION_FORMATION	0.0014859	0.0171187	0.4550599	-0.8710627	-1.859688	5	ENG TGFBR2 TGFB2	down	*
GO_MITOCHONDRIAL_TRANSLATIONAL_TERMINATION	0.0001589	0.0028269	0.5188481	0.4505913	1.859585	83	MRPL46 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 MRPS30 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 GADD45GIP1 MRPL9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 MRPS16 MRPL12 MRPL43 MRPL2 MRPS6	up	**
GO_MOTILE_CILIUM_ASSEMBLY	0.0015661	0.0178272	0.4550599	0.6423566	1.859284	18	MCIDAS MKS1 FOXJ1 DNAAF3 CCDC40 LRRC6 CENPJ BBS5	up	*
GO_REGULATION_OF_VASCULATURE_DEVELOPMENT	0.0000000	0.0000011	0.7337620	-0.3363139	-1.858745	276	ANGPT4 SEMA6A TMEM100 ACVRL1 IL1A SASH1 HMOX1 TEK PPARG HHEX GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 CDH5 ENG ECSCR GTF2I TBXA2R C5AR1 MIR27B TGFBR2 NFATC3 HSPG2 RHOA ANXA1 MIR146A MMRN2 PTPRM RAP1A ITGA5 HSPB1 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 FOXC2 NODAL RHOB GPR4 IL10 ROCK2 TNFSF12 TSPAN12 KLF4 ROCK1 THBS1 ADAMTS9 CLDN5 PDE3B ITGAX MIR24-2 RECK PIK3C2A PTGIS ANXA3 TGFB2 BTG1 FLT1 IL6 CD160 NOTCH1 ETS1 JAK1 RHOJ NPR1 CD34 RRAS KLF2 ISM1 MIR23A SOD2 MYOCD GATA6 ADAM10 FGF2 VASH1 EPN2 SEMA4A CXCR4 SP100 EPHA2 GLUL RAPGEF3 KIT FOXJ2 RNH1 SPHK1 STARD13 EGR1 GREM1 SERPINE1 CTSH HIPK1 ATF2 CX3CR1 C5 ITGB1 MIR640 MIR2355 EFNB2 HEY1	down	***
GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN	0.0000029	0.0000975	0.6272567	0.4087426	1.858242	179	TRIP13 FOXM1 KCNK5 CDC45 FANCI CENPF TIMELESS POLQ GGCT BRCA1 TTK NDUFS6 PTTG1 ESPL1 CCNB2 TRIB3 KNOP1 TYMS ALDOC SHMT2 COQ3 TOP2A AURKA TMEM177 RRM2 FSD1 GPSM2 MCM3 DCTPP1 MRPS11 BLM CDK1 POLE2 BIRC5 PLA2G2A GMNN NCAPG SEC61G KIF2A RTCB RNASEH2A EIF6 CHCHD2 UQCRFS1 DLGAP5 GSS MRPS34 PTGES2 SSRP1	up	***
GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION	0.0000247	0.0005947	0.5756103	0.4318536	1.857851	117	PKHD1 MCIDAS CEP72 SPICE1 MDM1 NEK2 BRCA1 BRSK1 STIL PLK1 XRCC2 CCNF HAUS5 RANBP1 CEP250 WDR62 KIF3B AURKA ODF2 POC1A KIF11 CHEK1 C2CD3 CCDC78 CDK1 CROCC CENPJ KIAA0753 SSX2IP CEP63 CEP192 TRIM37 SASS6 CKAP5 CHMP4C CDK5RAP2 HAUS6 HAUS4 CEP152 NUP62 CEP85 ALMS1 CHMP1A MARK4 CHMP2A CHD3 BCAS3 GOLGA2 MAP9 CLASP1	up	***
GO_NEGATIVE_REGULATION_OF_CARDIAC_MUSCLE_CELL_PROLIFERATION	0.0052563	0.0443562	0.4070179	-0.6257494	-1.857851	14	RBP4 TGFBR2 TBX5 MIR17HG SAV1 MEIS1 PTEN NOG JARID2	down	*
REACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_CYCLE_GENES	0.0052563	0.0443562	0.4070179	-0.6257143	-1.857747	14	CAV1 FOXO1 KLF4 CDKN1A BTG1 FOXO3 SMAD2 RBL2 SMAD4 CDKN1B	down	*
TERAMOTO_OPN_TARGETS_CLUSTER_1	0.0056869	0.0470661	0.4070179	-0.6987373	-1.857641	10	SC5D INSIG1 HMGCR TFRC	down	*
GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN	0.0000053	0.0001646	0.6105269	0.4065885	1.857417	181	TRIP13 PSPH PRIM2 BRCA1 METTL1 ANLN NDUFS6 IFT27 ACAD9 ALDH18A1 MCM2 CCT6A XPOT TAMM41 NUDT1 CISD1 KIF23 MKI67 TOP2A POLD2 LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD PHB CNPY2 CKS1B MRPL37 CDK1 BIRC5 CCT3 GMNN POLR3K MRPL17 TSPAN31 NOP2 TPD52L2 TUBG1 TACC3 MNS1 TRIM37 DUSP12 NUP85 RAD50 CENPK CKAP5 CDC20 RRP9 LRRC59 RPL7L1 CKAP2 MCM5 HAX1 NEURL4 RCC1 PDIA4 HAUS4 GADD45G RFC5 PDAP1 WDR77 INO80E HK2 PGAM1 SPR RPN1 POLR1A DDX52 CHERP DTD2 CYB5B RCN2 MRTO4 SRM PLK4 HRAS MRPL2 COQ5 GCSH ABCD3 PPA1 TIMM9 CRCP MTHFD2	up	***
GO_GLUCOSE_CATABOLIC_PROCESS	0.0012514	0.0150975	0.4550599	0.5924731	1.857413	25	PGM2L1 GPI GAPDH ALDOC PKM PFKP ALDOA ALDOB BPGM FOXK1 BAD HK2 PFKM PGAM1 TP53 ENO1	up	*
GO_WHITE_FAT_CELL_DIFFERENTIATION	0.0056486	0.0468397	0.4070179	-0.6632906	-1.857049	12	PPARG FABP4 FGF10 PRDM16 CEBPA PER2	down	*
GO_NUCLEOSOME_ORGANIZATION	0.0001323	0.0024420	0.5188481	0.4458712	1.856232	87	HJURP RUVBL1 CABIN1 TSPYL5 CENPA SOX9 MCM2 MIS18A SMARCD3 SMARCC1 CHAF1A CENPL CENPW CHAF1B ZNHIT1 CENPO ASF1B CENPH VPS72 CENPP HIRA CENPQ ANP32E CHD5 CENPK SUPT16H CENPM HMGA1 CENPT NFE2 SMARCC2 SMARCA4	up	**
PID_PDGFRA_PATHWAY	0.0049257	0.0422956	0.4070179	-0.5513279	-1.855940	20	CAV1 CRK SRF JUN JAK1 RAPGEF1 PIK3R1 GRB2 FOS	down	*
KAUFFMANN_DNA_REPLICATION_GENES	0.0000299	0.0007028	0.5756103	0.4238916	1.855902	127	CDC45 CENPF POLQ PRIM2 BRCA1 PTTG1 CDC6 MCM4 MCM2 ORC1 MCM8 LIG3 CHAF1A POLM POLA2 POLD2 MCM7 RRM2 MCM3 CHAF1B LIG1 TOPBP1 ORC6 REPIN1 BLM POLN SUPT5H SSBP1 POLE2 GMNN FEN1 EGF TEP1 POLL RAD9A CHTF18 MYBBP1A GINS2 POLD1 POLB NT5M CDC7 RPA1 MCM6 WRNIP1 MCM5 IGHMBP2 MSH2 RFC5 ABCF2 SMC2 PNKP CENPE	up	***
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_FETAL_UP	0.0000016	0.0000583	0.6435518	-0.3487044	-1.855856	177	CD300LF SASH1 DENND5A TAL1 OSBPL1A ST6GALNAC3 RAMP2 CD44 LMO2 SAMHD1 MYADM AQP9 ESAM S1PR1 MAN2B1 B3GNT5 CD33 PCYOX1 PPP3CA SIRPA IL18R1 PTPN12 ARRB1 CASP1 ST3GAL2 GRK5 SOCS5 MPL ITIH5 PER2 NR1D2 VIM CD302 PLEK KLRD1 NRROS PRCP CTSS MITF RAB31 IRF8 CD7 OGFRL1 CD34 SNX9 ITGA9 TSC22D1 CD86 CD81 MEIS1 RNF2 GEM ICAM1 CPQ PIP4K2A ARHGAP18 CCR9 PAIP2 THEMIS2 HEBP1 GRB10 MT2A	down	***
GTATGAT_MIR154_MIR487	0.0004181	0.0063688	0.4984931	-0.4183108	-1.855723	61	DYRK1A RHOA ZEB2 NLK CLK1 PDE4D GPM6A AGO4 KCNMA1 SMAD7 KPNA3 CREBRF MAGI2 SP3 RC3H1 TSHZ3 AZIN1 GALC NPTN IFFO1 TMEM184B RNF38 ENY2 BMI1 YTHDC1	down	**
GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN	0.0000009	0.0000353	0.6594444	-0.3489536	-1.855564	176	EREG KMO SC5D IL1A TUBD1 OSBPL11 SOWAHC ZC3H12C IL1B CCRL2 TMEM138 HEG1 ADAM17 SWT1 ITGA5 SIRPA MOB3C NFE2L2 CES1 BTG3 PDGFA TUBB6 ATP6V1B2 CD58 PTPN12 ST3GAL2 DAB2 STX3 MYO1B UXS1 PLEKHB2 KBTBD4 PAFAH1B1 PIK3R5 CRIM1 INO80C GABARAPL2 PSEN1 CRNKL1 PDCD6IP SERPINB8 DNAJA1 GSTO1 TPRA1 HIVEP2 MSMO1 BTBD7 TSC22D1 KYNU ANKRD12 ITPRIPL2 HSPA8 KIF1B CAMSAP2 CREG1 LINC00884 RNF13 ARFGAP3 MED31 PIM3 FADS3 ITGB1 ZFYVE1 EYA3 YRDC CYP51A1	down	***
GSE25677_MPL_VS_R848_STIM_BCELL_DN	0.0000018	0.0000645	0.6435518	-0.3540104	-1.854575	163	CD55 LMO2 SAMHD1 MYADM IER2 PDE2A B3GNT5 RAB33B PICALM KLF6 SLAIN2 PPP3CA AKT3 ITSN2 FLI1 ROCK2 FOXO1 LAPTM5 VIM SELL LBH GNAI2 CALM2 FAM76B ADD1 LMBRD1 AFF3 MTPN MYLIP FRY WASF2 STAT4 SH3BP5 JAK1 SNX2 IRF8 GMFG RAB8A TRAK2 SNX9 XYLT1 CC2D2B VPREB3 TEC ZCCHC10 IFNAR1 GNA13 PDE4B BRWD1 SSH2 SREBF2 IQGAP1 EHD4 CNN2 IRF2 ARHGEF18 ATP6V0A1 KMT2E PLEKHA2 TUBA1A ATP1B1 CSNK1G3 PIK3CG TRIM25 FCHSD2 ANKRD44 FAM107B RDH12 RFC1 CYTIP RASGRP3 SLAMF1 AIDA GTF2A1 PGAP1 TMEM64 SYNJ1 MED13 S100A10 BPTF LSP1 MAPK11 ARHGAP25 JAK2 RASGRP2 DMXL1	down	***
ALTEMEIER_RESPONSE_TO_LPS_WITH_MECHANICAL_VENTILATION	0.0000630	0.0013132	0.5384341	-0.3723079	-1.853855	106	CXCL3 IL1A IL1B GPR65 CCRL2 C5AR1 SLC15A3 BCL2A1 IL1RN PLA2G7 MAP3K8 LITAF TFEC MEFV BST1 PLAUR THBS1 CCL3 CXCL2 ATF3 SELL SELP FCER1G PLEK MAFF HCAR3 IL6 SOCS3 JUNB RCAN1 TREX1 GPR84 SOD2 CCR1 CCL20 CEBPD NFKBIA TNFSF9 CSF2 CSF2RB SERPINE1 CLEC4E	down	**
ZHAN_MULTIPLE_MYELOMA_PR_DN	0.0015671	0.0178300	0.4550599	-0.4405705	-1.853282	46	RGPD5 SLC7A7 NLK MOB3C PPM1K EPS15 TMEM167B TFEB DDHD2 BAZ2B KAT2B FGF2 PAXIP1-AS2 ARHGAP18 JMJD1C NR3C2 CBX7 SH3GLB1 CNTN1 ANKRD44 RASGRP3 PLCL1 GAB1 CYLD	down	*
GSE2935_UV_INACTIVATED_VS_LIVE_SENDAI_VIRUS_INF_MACROPHAGE_DN	0.0000036	0.0001150	0.6272567	-0.3522587	-1.852801	164	LPIN2 ABHD5 SNX10 TTC7B CD44 CTSW MYADM AQP9 GNPTAB FAM49A ZEB2 PDE2A ANXA1 ATP2B1 ENTPD1 ZDHHC2 LAIR1 IL18R1 PPP3CC AHNAK CASP1 PLEKHM3 FAM49B CTSD ITGAX VIM HOPX ATP6V0D2 ID2 PRF1 DSTN UNC5A IL7R PIK3R5 CALM2 CNOT6L HCST CAPN11 CCDC50 IFNGR1 PTGER4 EEA1 DAPK2 TBX21 CST7 NKG7 KLRC2 SMPDL3B CHPT1 GSAP ATXN1 POLK IL18RAP ARHGAP18 S100A4 KLRK1 RORA GIMAP4 TNFSF8 UBA6 ITGAL ITGB1 ARL4D S1PR5 ATP2B4 RPA2 DOCK5 CD226 IMPACT TTC39B MYO1F KLRC1 MYO5A ADAM19 TNFRSF1B F2RL2 SLAMF7 GZMK SOS2	down	***
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN	0.0000027	0.0000892	0.6272567	-0.3489216	-1.852372	174	ACP5 FCN1 CD101 HHEX FABP4 LTA4H FBP1 LIPA TMEM170B SAMHD1 MKNK1 CD9 FUCA1 GGA2 AVPI1 TXNIP CD36 NCEH1 TACC1 CLEC7A ZNF503 REV3L RNASE1 ABHD6 C1orf162 EVI2B TIMM10B PPT1 KIAA0513 MARVELD1 EVI2A RAP1GDS1 MPC1 UBASH3B CD300LB PRCP RBPJ RBP7 SLCO2B1 GLUD1 LPCAT2 VMO1 GAS2L3 FOS SORT1 VAV3 GALC MFNG PLA2G15 CALHM2 ARHGAP18 S100A4 METTL7A CD1E DOCK10 RHOT1 DISP1 C5AR2 CRTAP CCDC112 TREM2 DRAM2 PLXDC2 FPR3 MPV17 RCBTB2 SKAP2 SMIM4 CHKA WDFY2	down	***
GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP	0.0000016	0.0000565	0.6435518	-0.3517369	-1.852072	170	KMO ARHGAP31 SC5D IL1A MCOLN1 ZC3H12C IL1B CCRL2 FLVCR2 TMEM138 CD22 HPS5 PLA2G7 LACTB RRAGC ADAM17 ITGA5 SERINC1 CLN5 MOB3C NFE2L2 LAMTOR3 CES1 BTG3 PDGFA TUBB6 CD58 ST3GAL2 DAB2 STX3 MYO1B NFKB1 RIT1 IRAK2 PLEKHB2 PIK3R5 MMP19 PSEN1 CRNKL1 PDCD6IP SERPINB8 DNAJA1 GSTO1 PNPLA8 TINF2 SNX9 MSMO1 BTBD7 TSC22D1 EWSR1 CD81 KYNU WDR1 ITPRIPL2 SEC61B HSPA8 STAM2 FNIP2 KIF1B NABP1 CREG1 ARFGAP3 CYBA HMGCS1 OSGIN2 ZFYVE1 EYA3	down	***
LANDIS_ERBB2_BREAST_TUMORS_324_DN	0.0000060	0.0001807	0.6105269	-0.3665658	-1.851800	132	ABHD5 SOWAHC CLEC3B CYP4B1 THBD PTPRB LYL1 ST3GAL6 QKI ALAS1 GAS6 CD36 RRAGC CYB5A FZD4 SPTBN1 CES1 ZEB1 AHNAK SCP2 SORBS1 BNIP2 KLF4 PDE8A NKIRAS1 ADIPOR2 PPP2R5A HLA-DQA1 VWF SNRK CD34 ACSL1 CD151 CHPT1 TSC22D1 GNAI1 CPT2 APLP2 DECR1 MFNG	down	***
GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN	0.0000022	0.0000766	0.6272567	-0.3481526	-1.851675	184	ACP5 SC5D CTSW VAMP2 MAL LAMP1 TGFBR2 HEG1 TXNIP ATP2B1 EIF1 BTG2 LITAF HNRNPDL MCL1 CD37 SORBS3 CCNI MOAP1 SDCBP LEPROTL1 TPP1 SPAG9 LAPTM5 RBMS1 PER1 RNF139 PLCD1 NCOA1 FOXN3 BTG1 RBM39 AREG SGK1 NXF1 WTAP DDX5 HERC2P3 SNRK MOB1A CALM1 SRSF6 ZBTB1 FCGRT TOB1 RGS2 PDE4B TPT1 CXCR4 IFFO1 RPS13 OSER1 ICAM3 CYTH1 DAZAP2 MT2A SFPQ	down	***
GNF2_MCM5	0.0003909	0.0060702	0.4984931	0.4809640	1.851318	56	CPSF6 NDC80 GINS1 CDCA8 MCM4 MCM2 TYMS DTL ZWINT TOP2A POLA2 MCM7 MCM3 LMNB1 TOPBP1 FEN1 SF3B3 PA2G4 SSRP1 GINS2 CENPM MCM5 SRSF1 NUP62	up	**
NAKAMURA_ADIPOGENESIS_EARLY_UP	0.0011253	0.0139181	0.4550599	-0.4337302	-1.851193	51	INSIG1 FYN CCRL2 MYADM TGFBR3 LIFR CHMP1B GM2A PDE4D CYBRD1 FOXO1 SIK2 WASF3 ELK3 MT1L PIK3R1 IRS2 SOD2 CEBPD MT1M USP4 ZFP36 MT1E	down	*
GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN	0.0000027	0.0000911	0.6272567	-0.3557070	-1.850856	154	CD300LF FAM167A ABHD5 MS4A7 PDLIM2 ZC3H12C RUNDC3B S1PR1 RXFP1 CD9 EDEM1 CD36 DNAJC3 GM2A CYB561A3 LAIR1 C1orf162 SIRPA GRN PDE4D HERC3 FBXL5 TBC1D9 SPNS3 ST3GAL2 PLBD1 LY96 PDE8A MGAT4A UBE2E2 RUFY3 RASGEF1B HCK BCAR3 UTRN HCST TYROBP ACKR3 RALB NDST1 ZC3H12D ATXN1 CD81 MICU3 BMP2K PIP4K2A RPS13 PLGRKT CTSC DOCK10 NRP2	down	***
GO_SMOOTH_MUSCLE_CELL_DIFFERENTIATION	0.0005442	0.0078784	0.4772708	-0.4301528	-1.850730	54	EREG FOXF1 EDNRB WNT4 RAMP2 ENG FGF10 NFATC3 TMEM204 ZEB1 NPNT HES1 PIAS1 SRF MED28 NOTCH1 EPC1 SOD2 MYOCD GATA6	down	**
GO_HIGH_DENSITY_LIPOPROTEIN_PARTICLE	0.0011034	0.0137248	0.4550599	0.7000168	1.850609	13	SAA1 SAA2 CETP APOL1 PLTP HPR PON1 LIPC HDLBP	up	*
GSE22935_WT_VS_MYD88_KO_MACROPHAGE_UP	0.0000043	0.0001364	0.6105269	-0.3486467	-1.850559	180	FAM167A HVCN1 DCSTAMP TRPV2 PPP4R1 SAMHD1 SLC15A3 STX11 MARCO NCF2 GNPTAB LAMP1 CBL IGSF6 PILRA PDCL EDEM1 ANXA1 PLA2G7 ASAH1 EMILIN2 ITGA5 IFI30 LITAF TMEM123 CD37 SDCBP MEFV TPP1 ITGAX HPSE M6PR FCER1G ELK3 HCK NCKAP1L CD80 PGD RAB8B CD48 C1QA TYROBP SKIL GLIPR1 PTGER2 RAB8A SNX1 LPCAT2 AP3B1 MOB1A MFSD10 TMX3 DOK3 TGIF1 TGFB1I1 CCR1 SLC43A2 SELPLG	down	***
GO_MYELOID_LEUKOCYTE_MEDIATED_IMMUNITY	0.0000000	0.0000000	0.8513391	-0.3118880	-1.850190	453	SIRPB1 SLPI FOXF1 HMOX1 FCN1 OLR1 ACE PECAM1 HVCN1 CD55 GATA2 MNDA LTA4H CAT RAB44 CLEC12A PTPRB OSCAR CD44 PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA VAPA FUCA1 LAMP1 CBL SLC11A1 LILRB3 FGR RHOA DNASE1L3 CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ADAM17 ASAH1 RAP1A GM2A ANPEP PTX3 SERPINB9 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 RAB14 CD58 CST3 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE ARHGAP9 CD53 FCER1G GCA DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP IL6 CTSS PSEN1 SNAP23 VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG ENPP4 GLIPR1 GMFG SERPINB6 CAP1 PSMD12 ALDH3B1 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 DOK3 MILR1 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ORM2 BRI3 PLEKHO2 ADAM10 IST1 COMMD9 UNC13D LAT WDR1 HSP90AA1 HSPA8 METTL7A NHLRC3 KIT SIGLEC9 CTSC ARPC5 SNAP29 P2RX1 PSMD6 IQGAP1 CREG1 CNN2 ANO6 LYZ CYBA ATP6V0A1 CTSH TMEM30A ATP11B MAPK1 ITGAL FTL S100A8 RAB37 FPR1 KMT2E NFAM1 PIK3CG QSOX1	down	***
GO_MOTILE_CILIUM	0.0000424	0.0009433	0.5573322	0.4294338	1.849892	115	KLC3 CEP89 DNAH2 PMFBP1 SORD SPAG17 IFT27 AK8 RSPH1 SPAG16 TSGA10 IQCD ODF2 HAVCR1 TEKT2 WDR66 NME5 SLC9A3R1 IFT172 GAS8 DNAH11 DRC1 SPAG6 KIF2A AK7 DNAH5 TCTE1 IFT52 CATSPERG SPEF1 CATSPER3 NPHP1 EFCAB2 MNS1 IQCG TEKT3 SPA17 DNAJB13 IQUB ROPN1B CATSPER2 DNAI2 DYNC2H1 RSPH4A SPAG4 CATSPER1 CCDC181 DNAH1 ENKUR TACR1 ADAM15 TSSK4	up	***
GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY_PLUS_END_DIRECTED	0.0011752	0.0144217	0.4550599	0.5620820	1.849855	30	KIF1A KIF18B KIF14 DYNC1I1 DNAI1 KIF3B WDR78 KIF11 WDR60 KIF5A KIF19 DYNLL2 KIF20B WDR34 DNAI2	up	*
GO_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE	0.0015056	0.0173077	0.4550599	0.5668714	1.849772	29	NEK2 CCNB1 NDC80 RACGAP1 NUF2 AURKB ECT2 CDT1 BOD1 KIF2C MAD1L1 KNSTRN SPAG5	up	*
GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_DN	0.0000020	0.0000710	0.6272567	-0.3530872	-1.849738	163	CD300LF SGK3 OSBPL11 LIPA TRPV2 HSD17B11 LY86 S1PR1 MEF2A ANAPC15 MAN2B1 RRAGC UBL3 CLEC7A RNF144B ABCG1 TTYH2 STOM ARL11 APOC1 ATP6V1B2 ATP10A AHNAK EPOR KIAA0513 CEBPA LAPTM5 COTL1 ATF3 ATP6V0D2 VWF HEXB MYLIP CTSS PHACTR2 SLCO2B1 HPGDS VAT1 ADRA1A TYROBP IRF8 MIR23B MBP MSMO1 XYLT1 DCK ATP6V1A APLP2 RGS2 PLA2G15 GPX3 IQSEC1 LRP12 HAVCR2 TMEM184B SKI CYTH1 MMD ZFAND2A RNH1 CNR2 HMGCS1 CX3CR1 CD109 PTGS1 HEY1	down	***
GO_NEGATIVE_REGULATION_OF_CELL_ADHESION	0.0000002	0.0000089	0.6901325	-0.3387857	-1.849205	231	TNR DAB1 AJAP1 SEMA6A ACVRL1 SWAP70 DLC1 CCM2L ADTRP SPN LPXN RDX BMP2 CORO1C MYADM CDH13 PRKAR1A CD9 IL1RN RHOA APOD ANXA1 MIR146A SH2B3 PLXNA2 FZD4 HLX PAG1 JAM3 PLXNA4 RGCC IL10 NRARP DUSP3 PTPRO KLF4 THBS1 SOCS5 PDE3B PTPRC JAM2 SFTPD DUSP1 SMAD7 UBASH3B ARHGDIB GNRH1 KANK1 FAM107A CD80 NOTCH1 PDE5A MAP4K4 PODXL PIK3R1 RC3H1 TBX21 TIGIT PPM1F PELI1 CD164 MBP RUNX3 CD74 TGFB1 YTHDF2 LRRC32 MIA3 CD86 LGALS3 CLASP2 ADAM10	down	***
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN	0.0000056	0.0001713	0.6105269	-0.3520734	-1.847837	165	SGK3 EGR2 BMPR2 YPEL5 BCL2A1 AGPAT4 TEX2 WWC2 UBL3 BTG2 LUZP1 FOXP1 TRAF6 CRK CRTAM ZFYVE16 EFCAB14 LEPROTL1 MGAT4A CCL4 TEF CCSER2 SH3BP5-AS1 PPP2R5C CLIP4 IL7R RUFY3 AKIRIN1 VAMP3 MN1 PIK3R1 HERC1 RC3H1 ENTPD4 HOMER1 GFPT2 ASTE1 FOS TRAPPC10 ZRANB1 BAZ2B TSC22D1 ZBTB11 MIA3 MAP3K2 RIMKLB PDE4B ARAP2 PDLIM5 IL18RAP SERTAD1 EPHA4 PSME4 SOAT1 KLRK1 RORA EHD3 ZBTB40 ZBTB44 RABGEF1 VPS13D DKK3 FAM53B TSC22D2 ATP8A1 SNRPN SETD2 TMEM170A NR4A3 DUSP2 USP33 ZCCHC14	down	***
GO_TISSUE_MIGRATION	0.0000000	0.0000022	0.7195128	-0.3345187	-1.847790	261	ANGPT4 ACVRL1 SASH1 FOXF1 HMOX1 SOX18 TEK PECAM1 PPARG ADTRP GLIPR2 GATA2 EMP2 BMPER CORO1C CDH13 BMPR2 TBXA2R FGF10 MIR27B TGFBR2 RHOA ZEB2 ANXA1 MIR146A MMRN2 PTPRM HBEGF ARSB ADAM17 CLEC14A HSPB1 FOXP1 ADIPOR1 GATA3 NR4A1 RGCC NFE2L2 GRN AKT3 KANK2 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 TNFSF12 KLF4 THBS1 ADAMTS9 MIR24-2 PIK3C2A ACTG2 NUS1 ANXA3 MAPRE2 TGFB2 SRF PRCP KANK1 JUN NOTCH1 ETS1 MAP4K4 RHOJ PRKCE PPM1F PLCG2 EPPK1 TGFB1 MIR23A TGFB1I1 MIA3 CLASP2 MACF1 CCR6 FGF2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 SP100 EPHA2 GLUL KIT EDN1 PTEN FGFR1 NRP2	down	***
GO_LIPID_STORAGE	0.0003693	0.0058197	0.4984931	-0.4189146	-1.847785	59	ABHD5 OSBPL11 PPARG IL1B PLA2G10 LPL CAV1 CD36 MIR146A STARD4 GM2A ABCG1 MSR1 NFKB1 HEXB IL6 PNPLA2 EHD1 CRY1 ACACB SOAT1 SREBF2 NFKBIA	down	**
BIOCARTA_ATRBRCA_PATHWAY	0.0013674	0.0161685	0.4550599	0.6171563	1.847196	21	CHEK2 BRCA1 FANCA ATR FANCD2 CHEK1 FANCG FANCF RAD9A RAD50 RAD51 TP53 RAD1	up	*
GO_MEMBRANE_REPOLARIZATION_DURING_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.0024323	0.0248894	0.4317077	0.7096978	1.846883	12	KCNJ8 KCNH2 NOS1AP DLG1 KCNE3 RNF207	up	*
GO_CELLULAR_RESPONSE_TO_BIOTIC_STIMULUS	0.0000008	0.0000329	0.6594444	-0.3437543	-1.846718	189	CXCL3 KMO IL1A SASH1 EDNRB SCIMP CD55 IL1B LY86 MYD88 TBXA2R IL1RN TRIB1 RHOA TXNIP CD36 MIR146A CARD16 PPP1R15B CLEC7A TNIP3 LITAF SIRPA TRAF6 PDE4D IL10 CASP1 PTAFR LY96 CCL3 NFKB1 CXCL2 IRAK2 VIM AXL TLR4 ZMPSTE24 WFS1 IL24 HCK CD80 IL6 CARD8 IRF8 PRKCE MALT1 CXCL5 MAPK8 TGFB1 CD6 CD86 PLSCR4 KLRC4-KLRK1 PLAA PDE4B TSPO ICAM1 IL18 TFPI RIPK2 NLRP3 HAVCR2 NFKBIA KLRK1 CSF2 SERPINE1 CX3CR1 MAPK1 TREM2 ZFP36 WNT5A SHPK BCL10 CTR9 HMGB1	down	***
HALLMARK_MYC_TARGETS_V2	0.0004297	0.0065066	0.4984931	0.4797384	1.846601	56	SORD TBRG4 CDK4 PLK1 MCM4 CBX3 SLC29A2 AIMP2 DCTPP1 PHB PES1 UNG NOP2 PA2G4 PUS1 MYBBP1A RRP9 UTP20 MCM5 NOC4L RABEPK EXOSC5 FARSA HK2 MRTO4 SRM PLK4 NPM1 IMP4	up	**
AKL_HTLV1_INFECTION_DN	0.0007448	0.0100975	0.4772708	-0.4167420	-1.846227	60	IL17RB PECAM1 GPR65 FYN YPEL5 VAPA ANXA1 SERINC1 REV3L CPVL HOPX FRY RWDD1 JUN TSPYL1 PKIA CD86 CD3G GPR171 DUSP6 ITGB1 SERP1 PTGS2 CCNC GZMB PNISR DNAJB6 GZMA UFL1 UBE2J1	down	*
GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN	0.0000103	0.0002849	0.5933255	0.4061814	1.846118	178	TRIP13 CDC45 MCM10 ELOVL6 GGCT PBK CDK4 CDC6 SFXN1 RBBP8 MCM4 MCM2 PRC1 ORC1 DTL CCT6A SHMT2 XPOT MRPS35 CDT1 CCT2 NME1 RANBP1 MRPL15 EEF1E1 CCT5 POLD2 MCM7 CPD TOPBP1 DNAJC9 MAD2L1 RAD51AP1 DCTPP1 BLM CKS1B GMNN POLR3K PSMB5 MRPL17 FEN1 NUP205 PSMC4 PA2G4 POLR2H DNMT1 VBP1 DPP3 TUBG1 LMNB2 MLEC GINS2 ASNS POLD1 CCT7 CDC20 STOML2 BCL2L1 MCM6 MCM5	up	***
TOMIDA_METASTASIS_UP	0.0016529	0.0185192	0.4550599	0.6261509	1.845886	20	SLC16A9 CPLX2 TFAP2A PTTG1 ALG3 DNER TUBA3D PSMD2 CXCL1 CKAP4 ECH1	up	*
GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN	0.0000020	0.0000699	0.6272567	-0.3477161	-1.845789	178	WEE1 DENND5A LRRC8C SNX10 CLDND1 TTC7B CD44 CTSW ST3GAL6 AQP9 CYB5R3 BCL2A1 FRAT1 FGR ANXA1 KLF10 KLF6 PRSS12 GATA3 IL18R1 CRTAM TXN PPP3CC AHNAK CASP1 YBX3 KLF4 CTSD ITGAX HOPX ID2 CCL4 RECK PRF1 MBD2 SH2D2A N4BP1 MAPRE2 CD160 GABARAPL2 SLC35E4 GSTO1 EEA1 DAPK2 CD7 DYM CST7 FOS KRTCAP2 FOSB CHPT1 PIM1 TOB1 JUND RNF138 IL18RAP	down	***
GO_REGULATION_OF_LIPID_STORAGE	0.0028835	0.0282646	0.4317077	-0.4683889	-1.845762	37	ABHD5 OSBPL11 PPARG PLA2G10 LPL CD36 MIR146A ABCG1 MSR1 NFKB1 IL6 PNPLA2 EHD1 ACACB SREBF2 NFKBIA	down	*
FARDIN_HYPOXIA_9	0.0006186	0.0087712	0.4772708	0.8325958	1.845513	7	AK4 DDIT4 ALDOC FAM162A PDK1	up	**
GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP	0.0000051	0.0001572	0.6105269	0.4088045	1.845030	166	GRIA4 KCNK5 MCM10 GMDS FBXW8 TG BRCA1 DEPDC1B GINS1 CDCA2 CDK4 IQGAP3 ANLN POLE SNF8 ASPM NUF2 ECT2 GPI GRIN2A FIGNL1 DTL MIS18A KIF23 EME1 SAE1 RAB19 IFT43 CLSPN PASK BRI3BP DNAJC9 CKAP2L PFKP RAD51AP1 ABCB9 MRPS11 CAD GNPDA1 THOP1 KNSTRN KIF2A ETFB DDT SNRNP25 TACC3 AARSD1 TRIM37 LRWD1 FBXO44 ORMDL2 AAAS	up	***
GSE13485_DAY1_VS_DAY7_YF17D_VACCINE_PBMC_UP	0.0000520	0.0011173	0.5573322	0.4356484	1.844920	100	KIF1A KIF12 RIBC2 KLC3 PTPRT SPATA24 MYBPH PPP1R1B PAX9 DCST1 WFDC2 CHST4 SDK2 DIO2 SLC4A8 LAMC2 PCDHGB7 WDR72 LINC00265 PROM2 OXER1 GRHL2 C9orf163 PPIC PANX2 OVOL3 SEC16B S100A16 TTLL10 FTCD MADCAM1 ACOT11 VWA3A CCDC60 CNTN2 ELFN2 MEP1B ARHGEF39 TRIM67 FAM78B UBTF AQP4-AS1 KCNH4 ZNF740	up	**
MODULE_357	0.0004491	0.0067498	0.4984931	0.4792439	1.844771	55	COL17A1 SAA1 TFPI2 TP63 KRT5 S100A2 TENM2 COL7A1 AKR1C1 KRT15 GPX2 LAMC2 F2RL1 TRIM29 ITGB4 CDH3 HAS3 S100A9 KRT19 FXYD3 LIPG CXCL1 PTHLH FBN2 FGFBP1 KRT17 BARX2 KLK10 PTPRK ROPN1L	up	**
GO_SPINDLE_ELONGATION	0.0011287	0.0139515	0.4550599	0.8000112	1.844633	8	RACGAP1 AURKB PRC1 KIF23 MAP10	up	*
GO_OUTFLOW_TRACT_MORPHOGENESIS	0.0003997	0.0061708	0.4984931	-0.4093627	-1.844556	68	SMAD6 SOX18 TBX3 ENG FOLR1 SOX17 CITED2 BMPR2 TGFBR3 TGFBR2 TBX2 FOXC2 CLDN5 SEC24B HES1 MIR17HG TGFB2 RBPJ JUN NOTCH1	down	**
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN	0.0000000	0.0000014	0.7337620	0.3864479	1.844552	302	TRIP13 HELLS RUVBL1 CDC45 TICRR MCM10 GPT2 BUB1B UBE2T MPP6 PBK SLC2A1 TSFM BRCA1 GINS1 E2F8 SLC27A2 NUF2 PTTG1 CDC6 SFXN1 TFDP2 UHRF1 KNOP1 MCM4 MCM2 TYMS CDC25A UMPS MYBL2 XRCC2 DTL ACY1 TDRKH MCM8 GINS4 ZWINT RANBP1 MELK EXO1 KIF23 KCNN4 CHAF1A BUB1 PUS7 MCM7 E2F2 CLSPN RRM2 RAD54L SYT2 MCM3 CHAF1B PLXNA1 SLC9A3R1 ORC6 ACTL6A MAD2L1 PFKP RAD51AP1 DCTPP1 PIH1D1 SPC24 DSCC1 PKMYT1 BRIP1 BLM FADS2 GEMIN4 KNSTRN CKS1B ASF1B POLE2 RFWD3 SIGLEC12 CENPH CCM2 GMNN UNG NCAPG MCAT TCTN2 PSAT1 PDK1 FEN1 MRPS12 MTBP DIAPH3 HSPA4L CCNE1 KIF22 DPH2 TK1 DBN1 ESCO2 GINS2 ETV4 CENPK KLHDC3 CENPV DCUN1D5 CENPM FAM136A NOL6 MCM6 KIF21B MCM5 GINS3 EXOSC5 GGT5 ATAD2 TSR1 MSH2 CCNA2 SLC2A5	up	***
GO_CELL_SUBSTRATE_JUNCTION	0.0000000	0.0000001	0.7881868	-0.3194312	-1.844346	367	SLC6A4 LIMS2 ARHGAP31 TEK TSPAN4 DLC1 CAT LPXN RDX ENG CD44 CAV1 CORO1C CDH13 CDC42 NEDD9 IL1RL1 CD9 CBL HSPG2 RHOA NUMB ANXA1 ADAM17 CSRP1 ITGA5 HSPB1 PARVG ANXA5 CAV2 LCP1 TNS1 LAMTOR3 ARHGEF2 CNN1 SORBS3 EPB41L2 RHOB PTPN12 AHNAK SDCBP SORBS1 LIMS1 PLAUR KLF11 DAB2 PARVB VASP PTPRC VIM ACTR3 PEAK1 ADD1 MAPRE2 ACTR2 HCK PROCR FAM107A FLT1 SYNPO2 SNAP23 PDCD6IP LIMD1 RAC2 MAP4K4 HSPA1B RHOG RPL9 JAK1 FERMT2 CAP1 YWHAZ ITGA11 MCAM CD151 SPRY4 RRAS EPPK1 FLNC MME TGFB1I1 PDLIM1 ATP6V0C CD81 CLASP2 GNA13 ACTN2 ADAM10 ICAM1 ARPC2 EPB41L5 XIRP1 DCTN4 DIXDC1 ARL14EP HSPA8 ACTB HNRNPK EPHA2 RPS13 PARVA ARPC5 IQGAP1 CNN2 RSU1 EHD3 PPP1CB IRF2 CYBA CHP1 SVIL MAPK1 ITGB1 ZYX EFNB2 YWHAB CALR SLC9A3R2 BSG LMO7 PPFIA1	down	***
GO_3_5_DNA_HELICASE_ACTIVITY	0.0016846	0.0187595	0.4550599	0.6852098	1.844286	14	CDC45 GINS1 MCM2 GINS4 MCM7 BLM RECQL4 GINS2 MCM6 MCM5	up	*
REACTOME_MITOCHONDRIAL_TRANSLATION	0.0001423	0.0025779	0.5188481	0.4424622	1.844277	90	TSFM MRPL46 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 MRPS30 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 GFM2 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 GADD45GIP1 MTIF3 MRPL9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 MRPS16 MRPL12 MRPL43 MRPL2 MRPS6 MRPS7 MRPL35 MRPL13 MRPL33 MT-RNR1 MRPL19 MRPS15 MRPS10 MRPL38 MTRF1L MT-RNR2 MRPL10 MRPL23	up	**
PID_AP1_PATHWAY	0.0007448	0.0100975	0.4772708	-0.4162868	-1.844210	60	GATA2 FABP4 FOSL1 NR3C1 NFATC3 TCF7L2 BAG1 IL10 MAFG ATF3 DUSP1 ELF1 IL6 JUN ETS1 JUNB CREB1 FOS FOSB TGFB1 JUND EDN1 PTEN MT2A CSF2 EGR1 CDKN1B ATF2 IL5 EP300	down	*
GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN	0.0000103	0.0002849	0.5933255	0.4060850	1.843960	177	CDC45 FANCI NEK2 CCNB1 GGCT SORD PHGDH TTK GINS1 NIPSNAP1 AURKB CDC6 TPX2 MCM4 ORC1 CCT6A MYL6B CDT1 NME1 CHAF1A MKI67 PCCB EEF1E1 TOP2A POLD2 KIF2C WDHD1 RAD54L PKM CDC25C AIMP2 IDH2 MNAT1 PARP1 THOP1 TMEM106C CDK1 HDGF NPM3 UNG TRAP1 FADD ETFB SRD5A1 DNMT1 CCNE1 DLGAP5 FAH GALK2 PSMA5 SNRPA LMNB2 SSRP1 FHL2 PFAS CKAP5 AHCYL1 STAMBP MCM5 AP2S1 PYCR1 PRIM1 GBP1 ECHS1 CPOX ETHE1 VDAC3 OSGEP PCBD1 MRPS27 BCAT2 ENO1 RAD1	up	***
BIOCARTA_IL1R_PATHWAY	0.0043179	0.0384023	0.4070179	-0.5063501	-1.842872	27	IL1A IL1B MYD88 IL1RN TRAF6 MAP2K3 NFKB1 IRAK2 TGFB2 IL6 JUN MAPK8 TGFB1	down	*
GSE9988_LPS_VS_LOW_LPS_MONOCYTE_DN	0.0000431	0.0009561	0.5573322	0.4255962	1.842797	119	RIBC2 BBOX1 HS3ST1 FAM182B PAX9 SLFN13 MYO3B SOX2 PAGR1 RHOV CATSPERB STIL KRT16 CDC6 GRHL3 GRB7 ASXL3 GSDMB KIF15 C20orf197 BPHL AURKA GPR182 MYRFL ZYG11A NOL3 ATAD3C ARL16 PRRT3 ISOC2 KIF19 UQCC2 LINC00173 GAL3ST4 LGR5 TMTC2 RGS7BP ZBTB7B BCDIN3D-AS1 STAG3L4 SKAP1 TMEM254 SHCBP1 BMP8B TNKS1BP1 PPP6R2 PNKP MPG ANKS6 FRZB MUC1 ISLR ZNF740 NOS3 MORN3 PPARGC1B PNPO LGR4	up	***
LI_AMPLIFIED_IN_LUNG_CANCER	0.0000057	0.0001729	0.6105269	0.4116738	1.842375	155	LTF TSPAN8 KRT5 PDCD6 UCHL1 TFF3 LCN2 SPP1 GPI AKR1C1 SPINT2 SPINK1 NME1 LDHB SDHA CCT5 CBX3 FGG ZNF146 PKM SOX4 PFN2 MDK SPINT1 PFKP IDH2 ALDOA CLDN9 HDGF CCT3 GIPR TRIM2 SNRPE DAP LAPTM4B COL1A1 COL1A2 GALNS JTB ENC1 MARCKSL1 COL11A1 TSTA3 ERBB3 ABCC3 HAX1 PSMB4 CKAP4 CEACAM5 CDH1 SNRPD2 NME4 PTPRF ERBB2 UBE2C ENO1 MUC1	up	***
GO_ENDOCARDIAL_CUSHION_DEVELOPMENT	0.0013274	0.0158487	0.4550599	-0.4551363	-1.842320	39	TMEM100 ACVRL1 FOXF1 BMP2 ENG BMPR2 TGFBR2 TBX2 SNAI1 TBX5 DCHS1 TGFB2 RBPJ NOTCH1	down	*
TURJANSKI_MAPK7_TARGETS	0.0036532	0.0338908	0.4317077	-0.7715090	-1.841517	7	FOSL1 MEF2A ETS1 FOS	down	*
GO_SPLICEOSOMAL_SNRNP_ASSEMBLY	0.0010312	0.0130100	0.4550599	0.5304933	1.841188	36	COIL GEMIN7 GEMIN4 PRPF6 SNRPE GEMIN5 PRMT7 GEMIN6 CD2BP2 SNRPD1 LSM4 PRMT5 SNRPD2 WDR77 PRPF31 SNUPN PRPF3 SNRPC SART1 SART3 GEMIN2 CLNS1A PRPF19	up	*
HALLMARK_APOPTOSIS	0.0000092	0.0002594	0.5933255	-0.3572016	-1.840686	144	WEE1 EREG SC5D IL1A HMOX1 IL1B BMP2 CD44 CAV1 TGFBR3 NEDD9 CASP9 TXNIP ANXA1 DNAJC3 LMNA BTG2 HSPB1 BTG3 MCL1 DIABLO RHOB PPT1 CASP1 ROCK1 CDKN1A ATF3 CCND2 PRF1 SMAD7 ADD1 TGFB2 ETF1 IL6 PSEN1 JUN DNAJA1 IFNGR1 TIMP2 PEA15 PPP3R1 SOD2 LGALS3 TSPO BNIP3L GPX3 IL18	down	***
DELPUECH_FOXO3_TARGETS_DN	0.0008377	0.0110921	0.4772708	0.5349021	1.840309	34	FOXM1 NEK2 CENPF PRC1 SHMT2 XPOT ZWINT MKI67 AURKA PFN2 NUSAP1 MB KIF22 DTYMK HAX1 PYCR1 APEX1 UBE2C	up	*
GO_DNA_STRAND_ELONGATION	0.0014383	0.0166977	0.4550599	0.6147604	1.840025	21	GINS1 POLE MCM4 LIG3 GINS4 POLD2 MCM7 MCM3 LIG1 DNA2 GINS2 RAD50 GINS3 DCLRE1B POT1 POLD3 RFC3 RFC4 PCNA	up	*
chr7p13	0.0019076	0.0206326	0.4550599	0.5417125	1.839732	33	NPC1L1 COA1 NUDCD3 TBRG4 TUBG1P SPDYE1 POLM POLD2 YKT6 DDX56 CCM2 ZMIZ2 SNORA5C URGCP	up	*
SANSOM_APC_TARGETS_UP	0.0000405	0.0009094	0.5573322	0.4293385	1.839415	113	HS3ST1 EPHB3 FOXA3 UBE2T TNNI1 CDCA7 TUBB2B ECT2 SOX9 MCM2 SP5 CA12 DTL REC8 MCM7 MAD1L1 MSX1 ABCC5 RNF43 PASK MCM3 SOX4 ANG MSI1 HES6 EHF SKP2 PARP1 URI1 KRT18 GNB1L UNG PSAT1 DIAPH3 GOLGA3 INTS7 ADAT1 TUBB2A EPHB2 DTYMK ZNF282 MARCKSL1	up	***
GO_PYRIMIDINE_NUCLEOTIDE_METABOLIC_PROCESS	0.0011606	0.0142764	0.4550599	0.4854533	1.839340	52	GPAT2 TYMS UMPS SMUG1 TAMM41 NME1 NME9 NME5 DCTPP1 CAD UCK2 UNG ENPP3 UCKL1 UPP2 MBD4 DHODH DTYMK AGPAT5 LCLAT1 NT5M	up	*
MODULE_297	0.0004735	0.0070258	0.4984931	0.4805669	1.838529	54	COL17A1 SAA1 TFPI2 TP63 KRT5 S100A2 TENM2 COL7A1 AKR1C1 KRT15 GPX2 LAMC2 F2RL1 TRIM29 ITGB4 CDH3 HAS3 S100A9 FXYD3 LIPG CXCL1 PTHLH FBN2 FGFBP1 KRT17 BARX2 KLK10 PTPRK ROPN1L	up	**
chr3q22	0.0009424	0.0121349	0.4772708	0.4645587	1.838143	63	CPNE4 TF CEP70 FAM86HP TMCC1-AS1 TMCC1 EPHB1 PCCB IL20RB MRPL3 NME9 SLC35G2 TOPBP1 NEK11 ALG1L2 RAB6B SNORA58 CEP63 KY NUDT16	up	*
GSE30083_SP3_VS_SP4_THYMOCYTE_UP	0.0000097	0.0002714	0.5933255	0.4111005	1.837011	154	TFPI2 KCNMB2 ABCC2 MEX3A COL27A1 TOX3 TUBB2B GINS1 TTC26 CHRNA7 BCL2L14 GRHL3 LDHB KIF23 RND2 CBLC CBX3 SSPO ABCC5 TEKT2 TMEM45A ADM2 DUSP23 TRIM11 WDR60 ARMC12 PKMYT1 IPO9 SLC45A3 PLOD2 CROCC CCDC61 ABHD17C TNK2 CTXN1 TTC23L SMO TMEM120B CBX1 SPEF1 ALDH7A1 JMJD4 TJAP1 EDARADD CCDC159 DHTKD1 ABCC9 VWA3B NMNAT1 FFAR2 MARCKS ANK3 ZNF286A FLRT1 CAPN10 TCTEX1D1 SOX12 F13A1 CTTN PTPRF CHL1 ZNF354B PTOV1 BFSP2	up	***
GO_POSITIVE_REGULATION_OF_EPITHELIAL_CELL_MIGRATION	0.0000108	0.0002966	0.5933255	-0.3640279	-1.836999	135	ANGPT4 SASH1 HMOX1 TEK GLIPR2 GATA2 BMPR2 FGF10 MIR27B TGFBR2 ANXA1 MIR146A HBEGF ADAM17 HSPB1 FOXP1 GATA3 NFE2L2 GRN AKT3 FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 THBS1 PIK3C2A NUS1 ANXA3 MAPRE2 TGFB2 JUN ETS1 MAP4K4 RHOJ PRKCE PPM1F PLCG2 TGFB1 MIR23A CLASP2 CCR6 FGF2 EPB41L5 RTN4 IQSEC1 EDN1 FGFR1 NRP2 FLT4 CTSH HAS2 CALR WNT5A HMGB1 ATOH8 DOCK5 SIRT1 PTGS2 SEMA5A CAPN7	down	***
chr11q21	0.0036690	0.0340128	0.4317077	-0.5151155	-1.836917	25	SLC36A4 AMOTL1 CCDC82 CEP57 FAM76B MAML2 SNORA1 MTMR2 ANKRD49 MED17 ENDOD1 C11orf54 TAF1D SCARNA9	down	*
chr1q21	0.0000247	0.0005947	0.5756103	0.4154316	1.836567	142	GPR89A DCST1 LYSMD1 S100A2 THEM4 CREB3L4 THEM5 EFNA3 FLAD1 EFNA4 NBPF20 DCST2 TDRKH C2CD4D GOLPH3L HRNR SEMA6C FLG SETDB1 UBE2Q1-AS1 HORMAD1 TARS2 NUDT17 OAZ3 POLR3C PSMD4 RAB13 CKS1B ACP6 VPS72 PIAS3 ZNF687 ILF2 SNX27 S100A16 UBE2Q1 ADAR S100A9 ANP32E NBPF10 S100A13 FLG-AS1 JTB ZBTB7B ANXA9 C1orf56 PYGO2 HAX1 PIP5K1A PSMB4 BCL9 NBPF14 NBPF18P SCNM1 CCT8P1 MRPL9 RPRD2 UBAP2L ADAM15 CGN PRPF3 RORC SLC39A1 PI4KB NBPF9 POGZ MLLT11	up	***
GO_ALPHA_ACTININ_BINDING	0.0037777	0.0347211	0.4317077	-0.5147966	-1.835780	25	PDLIM2 PPARG KCNA5 SYNPO2 PKD2 PDLIM1 KCNN2 PRICKLE4 PDLIM5 ADORA2A	down	*
HAHTOLA_SEZARY_SYNDROM_DN	0.0016257	0.0183127	0.4550599	-0.4716676	-1.835655	36	CTSW SERPINB9 HOPX CCL4 KLRD1 MATK CD160 KLRB1 IL2RB IRF8 NKG7 VAV3 SESN1 IL18RAP PTCH1 KLRF1 ZBTB16 GZMB DUSP2 KLRC1 GZMK	down	*
SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_UP	0.0016438	0.0184486	0.4550599	0.5624585	1.835372	29	IGHV4-61 KCNK5 MCM10 CP CENPF KRT16 LDHB TTLL4 TRIM29 EGFR CXCL9 TNFRSF21 CDH3 CHST3 MMP7 MCM5 SCRG1 RARRES1	up	*
MORF_JUND	0.0006755	0.0093914	0.4772708	-0.4263049	-1.834175	54	IER2 RHOA FBXO7 MCL1 RPL17 NXF1 RPL9 DDX5 UBB RPL21 JUND TPT1 HNRNPK DAZAP2 EIF4A2 EIF4G2	down	**
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN	0.0000043	0.0001370	0.6105269	0.4053551	1.833907	173	EGLN3 BDH1 CCDC34 PIF1 PTTG1 GPI PRC1 ACY1 RUVBL2 HLTF TP53BP1 AURKA WDR3 POLD2 TMEM45A WDHD1 KISS1R CDC25C SALL2 SARS2 THYN1 SPC24 BRIP1 OGFOD2 FNTB COMMD4 IDH2 PSRC1 CASP6 CKS1B C12orf75 MEA1 TMEM106C CENPJ UCK2 WDR54 GOT2 TRAP1 MRPL17 KIF2A FEN1 EZH2 LRRC42 SAPCD2 ETFB IGSF3 POLR2H SNRNP25 DNAJC17 FAH OSBPL3 RAD51D DTYMK FAF1 MCM5 TDP1 TMUB1 HAUS4 LSM4 TXNL4A ZNF780A CEP152 PRIM1 ELOVL4 ATOX1 ZWILCH POP4 SEPHS1 PCBD1 BCAT2 MRPS26 CORO1B C9orf40	up	***
GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000068	0.0002000	0.6105269	0.4097009	1.833546	155	KIF18B NDC80 DEPDC1 TTK CDCA2 RACGAP1 GTSE1 KIF14 ANLN STIL NUF2 CDCA8 AURKB ECT2 TPX2 FIGNL1 PRC1 ALDOC DTL ITGA2 HMMR KIF23 PON3 MKI67 KIF15 KNTC1 BUB1 TOP2A E2F2 CLSPN DPCD CDCA5 RAD54L KIF11 CDC25C MAD2L1 CKAP2L GPX8 CDKN2C ASF1B CDK1 BIRC5 PLCH1 KCTD13 NEIL3 SPAG5 SEMA4F HSPA4L DLGAP5 TACC3 KIF22 ARL6IP4 CASP7 ESCO2 HID1 SPAG1 GALNT3 POLD1 TRAF3IP1	up	***
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN	0.0002034	0.0034911	0.5188481	-0.4039737	-1.833121	71	CXCL3 IL1B PTPRE CD44 FOSL1 IL1RN SLC11A1 TXNIP ITGA5 PDGFA RHOB PLAUR CCL3 NFKB1 DUSP1 SOCS3 RAC2 JUNB CD83 UBB BCL6B EHD1 TSC22D1 PIM1 ETS2 IL18RAP TRAF1 NFKBIA TNFSF9 HERPUD1 CSF2RB BCL10 CSF3 PTGS2 DUSP2 MT1X CDC42EP4	down	**
chr20q13	0.0000036	0.0001150	0.6272567	0.3985099	1.832855	192	WFDC10B PTPRT SPATA25 WFDC3 SLC13A3 RBBP8NL ZMYND8 EYA2 WFDC2 RN7SKP184 TSHZ2 HNRNPA1P3 L3MBTL1 BCAS1 TOMM34 ACOT8 MYBL2 SGK2 LIME1 ZFP64 NEURL2 OSBPL2 CYP24A1 C20orf197 WFDC13 AURKA SLC2A10 SYCP2 GNAS-AS1 PLTP FAM209A SAMD10 MIR941-2 ZNF512B ABHD16B DNTTIP1 DIDO1 BCAS4 PRPF6 UCKL1 GDAP1L1 IFT52 SNX21 TPD52L2 ZGPAT ARFRP1 PABPC1L SLC35C2 MRGBP ADNP ATP9A SALL4 SPINT4 ZSWIM3 ZSWIM1 CABLES2 TCEA2 LSM14B KCNB1 MIR941-1 PPP1R3D FITM2 GID8 RTEL1-TNFRSF6B STMN3 OGFR ARFGAP1 RTEL1 ZNF217 ADRM1 PFDN4 UBE2C TAF4 NPEPL1 ZNF831 ZBP1 MTG2 SS18L1 PMEPA1 CSTF1	up	***
GSE17301_CTRL_VS_48H_ACD3_ACD28_STIM_CD8_TCELL_DN	0.0000028	0.0000944	0.6272567	-0.3463231	-1.832852	172	CXCL3 SLC31A2 ZMYND15 SWAP70 ZC3H12C PID1 SLC6A12 CAV1 MYD88 STX11 ALAS1 MARCO IGSF6 PILRA PDE2A KCNAB1 ANXA1 PLA2G7 NDUFAF1 MAP3K8 SPI1 TFRC MCL1 SYNPO KCNMA1 VASP NFKB1 GSDMA CD302 N4BP1 PIK3R5 TLL1 ARHGDIB GLB1 HCK RBPJ SRSF3 SERPINB8 MTMR14 LIMD1 CTSZ HSPA1B JUNB PTGER4 MOB1A CD74 SMPDL3B TGFB1 EHD1 GSAP FPR2 IFNAR1 GPR84 SOD2 GPR18 PDE4B ICAM1 PDLIM5	down	***
KEGG_TGF_BETA_SIGNALING_PATHWAY	0.0003187	0.0051287	0.4984931	-0.3961046	-1.832850	76	SMAD6 ACVRL1 BMP2 BMPR2 TGFBR2 RHOA ZFYVE16 NODAL ROCK2 ID3 ROCK1 THBS1 ID2 SMAD7 INHBA TGFB2 ID4 PPP2CA PPP2CB TGFB1 ZFYVE9 LTBP1 SMAD2 RBL2 CREBBP SMAD4 ACVR1C MAPK1 NOG EP300 GDF7 SKP1 BMPR1A	down	**
GO_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	0.0001252	0.0023280	0.5188481	-0.3928778	-1.832841	79	CD55 TGFBR2 IL23A RHOA ANXA1 ADA HLX GATA3 MAPK8IP1 SOCS5 PTPRC SMAD7 NCKAP1L CD80 CD160 CD83 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 CD81 IL18 RIPK2 NLRP3 ADORA2A ZBTB16 HMGB1 CD3E IRF1 RC3H2 IRF4 NFKBIZ EBI3 CBFB PNP	down	**
TERAMOTO_OPN_TARGETS_CLUSTER_7	0.0010649	0.0133428	0.4550599	0.6401579	1.832815	17	GPT2 TFAP2A PSPH PHGDH SPP1	up	*
GO_DNA_RECOMBINATION	0.0000010	0.0000383	0.6435518	0.3912178	1.832567	223	TRIP13 RUVBL1 CDC45 PARPBP TIMELESS POLQ PAGR1 MND1 PIF1 BRCA1 NABP2 FIGNL1 RBBP8 MCM4 MCM2 RAD54B XRCC2 MCM8 LIG3 GINS4 MAGEF1 RUVBL2 EXO1 TP53BP1 POLM RHNO1 AUNIP TOP2A EME1 REC8 MCM7 MMS22L PRKDC HELB RAD54L MCM3 EME2 CHEK1 ACTL6A RAD51AP1 XRCC1 THAP10 BRIP1 BLM ERCC2 RECQL5 PARP1 POLN RFWD3 UNG AP5Z1 FEN1 MAD2L2 RECQL4 TEP1 DCLRE1C POLL RAD51D GINS2 POLB ATAD5 SLX4 CDC7 RAD50 ANKRD31 KLHDC3 UBQLN4 PGBD5 PALB2 RPA1 FANCM MCM6 XRCC4 MCM5 ZRANB3 IGHMBP2 MSH4 MCRS1 MSH2 NFRKB RTEL1 STAT6 INO80E RAD51 PAXIP1 SIRT6 TONSL BCL6 TCF3 SWI5	up	***
CTR9_TARGET_GENES	0.0008439	0.0111573	0.4772708	-0.4358592	-1.832494	49	SLPI TMEM138 SRSF7 ALAS1 CCNL1 ZEB2 EDEM1 TRA2B HNRNPU FBXL5 TAPT1 RBM39 RPL9 SNX22 YWHAZ TLDC2 CSDE1 BAG6 AMD1 TPT1 HNRNPC SFPQ	down	*
NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON	0.0018041	0.0197549	0.4550599	0.5474903	1.832203	32	DCST1 THEM4 THEM5 EFNA3 FLAD1 EFNA4 DCST2 TDRKH OAZ3 CKS1B ZBTB7B PYGO2 MRPL9 ADAM15 RORC MUC1 RUSC1 PMVK	up	*
GO_NEGATIVE_REGULATION_OF_CELL_MIGRATION_INVOLVED_IN_SPROUTING_ANGIOGENESIS	0.0035859	0.0335209	0.4317077	-0.5812734	-1.831956	17	TBXA2R RHOA MIR146A MMRN2 KLF4 THBS1 NOTCH1	down	*
SMID_BREAST_CANCER_RELAPSE_IN_LIVER_DN	0.0015126	0.0173512	0.4550599	0.7945117	1.831953	8	PCSK6 DNAJC12 STC2 RND2 ARNT2	up	*
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN	0.0000033	0.0001067	0.6272567	0.4042516	1.831899	175	CCDC34 ASPM FLAD1 TTC26 EFNA4 TPX2 ACY1 CCT6A SRPK1 RUVBL2 DNPH1 NLE1 WDR3 POLA2 WDHD1 CHAF1B LMNB1 THYN1 ACTL6A RAD51AP1 TIMM50 BRIP1 OGFOD2 CKLF PPIL1 CKS1B MEA1 TMEM106C CENPJ BIRC5 GOT2 FEN1 EZH2 FADD LRRC42 OARD1 SF3B3 ETFB RNASEH2A SNRNP25 COA3 DNAJA3 SLC37A4 MRPL52 TK1 DTYMK ZNF239 ASNS SAP30 SND1 NIF3L1 VPS25 CENPM STOML2 MRPS33 MCM5 TDP1 LSM4 ZNF780A SUV39H2 CCNA2 PRIM1 DCPS ATOX1 ZWILCH GBP2 CDK5 MTHFD1 PAICS ZC3HAV1L TPRN ZNF367 PPP1R14B FTSJ3 RPP25 MRPL12 GSTP1 CLPP PSMB10 RNF8 DCLRE1B HDDC3 ARMC6 RMI1 TIPIN NUDCD1 ORC5 CCDC124 CTPS1 TMEM14A PSMD8 MPLKIP	up	***
GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN	0.0000033	0.0001067	0.6272567	0.4042073	1.831698	175	PCSK6 TRIP13 CDC45 FANCI BUB1B CENPF PBK PIF1 BRCA1 DEPDC1B E2F8 SLC27A2 ANLN SPP1 CDCA8 KNOP1 SMPDL3A XDH NCAPD2 CDT1 KIF23 STAG3 MKI67 SLFN5 KNTC1 TOP2A SAE1 MCM7 TPCN1 RRM2 TTLL12 CDCA5 WDHD1 CCDC89 SBK1 KIF11 GPR146 SEC61A1 LIG1 HES6 PKMYT1 SLC25A10 PSRC1 INCENP CKS1B TMEM106C ANAPC5 KCNE3 SPAG5 CENPP QPRT CEP192 KIF22 ARL6IP4 HIP1R POLD1 CDC7 CENPM ARHGAP22 CENPT CEP152 CKAP4 PRIM1 CDH1 PRR11 SHCBP1 ZWILCH RNF213 CENPE POLR1A CDC25B NELFA ZBP1 NLRC5 NCAPH	up	***
REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX	0.0015990	0.0180984	0.4550599	0.7296964	1.831486	11	CDC6 E2F3 ORC1 MCM8 E2F2 ORC6 E2F1	up	*
REACTOME_GOLGI_TO_ER_RETROGRADE_TRANSPORT	0.0000356	0.0008134	0.5573322	0.4219898	1.829875	122	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 DYNC1I1 COPB2 KIF27 DCTN2 KIF23 BICD1 KIF15 COPG2 COPG1 PAFAH1B3 KIF3B KIF2C KIF11 KDELR2 KIF3C TMED3 NSF KIF5A STX18 KIF19 KIF2A DYNLL2 RAB6B TUBB2A TUBA3D KIF22 ARF5 TUBA8 KIF21A KIF20B KLC2 KLC4 KDELR3 GBF1 DYNC1LI2 KIF21B COPZ1 ARFGAP1 TUBA4B COPA TMED9 CENPE COPZ2 TUBA1C	up	***
GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000092	0.0002600	0.5933255	-0.3500746	-1.829652	162	EPAS1 PHACTR1 PECAM1 CD55 LRRFIP1 COQ2 GFOD1 RTN3 MEF2A BCL2A1 FUCA1 TGFBR2 TRIB1 GGA2 SERINC1 IL18R1 RAB14 ATP6V1B2 ZMIZ1 SDCBP PTAFR ZCCHC24 THBS1 ERP44 CXCL2 CD302 UBE2B SLC6A6 GNAQ RSL24D1 SNN MED28 CTSS PSEN1 PGD CRNKL1 PIKFYVE DAPK2 RPS6KA1 DENND4A RALB TINF2 ACSL1 FOS BTBD7 SORT1 OSGIN1 PIK3C3 RXRA SELPLG RLF CYB5R4 TBC1D1 ACACB OSER1 DAPK1 THEMIS2 CREG1 SFPQ PPP1CB DCUN1D2 RABGEF1 HAT1	down	***
GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP	0.0000066	0.0001946	0.6105269	-0.3451295	-1.829373	181	FAM167A FYN CCRL2 NEDD4L RTN3 PRKAR1A GIMAP6 RFTN1 CCNL1 DNASE1L3 PDE2A KIAA0355 EIF5 MAP3K8 LITAF BFAR NFE2L2 KDSR STK17B GAPVD1 NR1D2 M6PR ELMSAN1 GNAQ NUS1 USP16 BTG1 NINJ1 ARHGAP17 RYBP SGK1 RBM34 CPEB4 ST6GALNAC4 FOXN2 EPC1 TBC1D12 BAG5 ATXN1L IFRD1 GMFG GPR183 ATP6V0D1 CD164 AZI2 CD74 AZIN1 PEA15 VPREB3 CDC37L1 IRS2 RELL1 STK40 RNF2 RLF SFT2D1 RIPK2 PLGRKT RBM48 LYSMD3 MAFK CYTH1 ZFAND2A BANK1 FNBP1 CNR2 MZT1 OSGIN2 SLC26A11 CSNK1G3 PTDSS1 GPR137B SERP1 FCHSD2 MAPK7 KCTD18 C15orf48 EIF4E3 CBFB RANBP2 WHAMM CCNT1 GNL2 FEM1C TANK EZR MAT2A FGL2 EXOC5 PDS5A CMTM7	down	***
STANHILL_HRAS_TRANSFROMATION_UP	0.0025204	0.0255665	0.4317077	-0.8567511	-1.829133	5	HMOX1 HSPB1 DUSP1 JUN FOS	down	*
GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_UP	0.0000027	0.0000892	0.6272567	-0.3439393	-1.828718	175	EPAS1 PDLIM2 ASGR1 OSBPL11 PECAM1 OSBPL1A CAT THBD LYL1 SAMHD1 FCER1A RTN3 SLC25A30 IL1RN TGFBR2 SYNC CD36 DPEP2 SPG21 RNF125 TMEM38B EVI2B PPT1 SDCBP CASP1 KLF4 DAB2 TPP1 PAPSS1 CD302 SFTPD SS18L2 PINK1 WFS1 LMBRD1 HEXB ARHGAP17 PRKRA TECR CYB5R1 SH3BP5 RAB31 KCTD12 TMEM251 GMFG PTGER2 MBP VAV3 DECR1 CLEC2B CCNH RXRA MOB3B PCM1 CPQ CCDC69 ALDH6A1 GPD1L S100A4 ARPC5 CCND3 EMC3 RNF13	down	***
GO_NUCLEAR_CHROMOSOME_TELOMERIC_REGION	0.0001943	0.0033570	0.5188481	0.4371122	1.828644	91	THOC3 PIF1 NABP2 MCM4 MCM2 ORC1 TP53BP1 CBX3 ATR MCM7 PRKDC MCM3 XRCC1 PML PARP1 CBX5 CDK1 DNA2 FEN1 CBX1 TELO2 DCLRE1C RAD51D POLD1 SLX4 RAD50 RPA1 MCM6 THOC5 WRNIP1 MCM5 MSH2 RAD51 SIRT6 APEX1 NAT10 NHP2 DCLRE1B DCLRE1A POT1 XRCC5 CTC1 ORC5 MEN1 XRCC6	up	**
REACTOME_MITOTIC_SPINDLE_CHECKPOINT	0.0000682	0.0014002	0.5384341	0.4317526	1.828422	100	BUB1B NUP107 CENPF NDC80 PLK1 NUF2 CDCA8 AURKB CENPA DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 MAD2L1 CENPO SPC24 INCENP ANAPC5 CENPH BIRC5 KIF2A ANAPC7 DYNLL2 CENPP RANGAP1 CDC23 CENPQ ANAPC1 NUP85 CENPK CKAP5 CDC20 CENPM DYNC1LI2 CENPT ANAPC2 ZWILCH SEC13 CENPE UBE2C PPP2R5D CLASP1 DYNC1H1 DSN1 PPP2R5E NSL1 RCC2	up	**
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN	0.0000031	0.0001014	0.6272567	-0.3443876	-1.828120	178	EPAS1 LPIN2 LPXN GPR65 PLEKHA1 S1PR1 NEDD9 FUCA1 ATF7IP2 ABCB1 IER2 SH2B3 SLC7A7 CACNA2D2 TMEM204 KLF10 SERPINB9 TOR1AIP1 SPTBN1 CRTAM PDGFA ADARB1 PTPN12 FOXO1 LEPROTL1 ID3 COTL1 PTPRC LBH CD53 SMAD7 EVI2A PPP2R5A DCHS1 ARL6IP5 SGK1 IL2RB INPP5B RAB8B RAC2 JAK1 CCR7 GPR183 RASSF2 HIVEP2 CD6 DOK2 SPOCK2 PDE4B PHLPP2 GIMAP5 PTCH1 G3BP2 ULK2 CAMSAP2 GRB10 GIMAP4 IL16 EHD4 MAN1C1 SMPD1 HNRNPH1 EGR1 PRKCH ICOS	down	***
BIOCARTA_FCER1_PATHWAY	0.0034179	0.0323158	0.4317077	-0.4638548	-1.827894	37	FCER1A NFATC3 PPP3CA PPP3CC FCER1G CALM2 JUN PIK3R1 GRB2 FOS CALM1 MAPK8 PAK2 MS4A2 MAPK1 PIK3CG MAP3K1	down	*
GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0000156	0.0004088	0.5756103	0.4127609	1.827797	144	KRT5 XYLB PBK CDCA2 ESPL1 CCNB2 KNOP1 MCM2 CCNF PVT1 NME1 RANBP1 DNPH1 EXO1 C19orf48 MKI67 ANO7 EME1 CDCA5 RAD54L PDZK1IP1 AHCY PFKP DCTPP1 SNAPC4 PPP5C THOP1 NCAPG2 NUP205 RAB11FIP4 MYO19 C19orf44 SSRP1 KCNC3 MYBBP1A MFSD2A AGPAT5 NRF1 POLD1 ELAC2 RAD50 CHPF CDC20 CENPM RRP9 NOB1 LSM4 NEFH PYCR1 PRIM1 RTEL1 MRPL55 PDAP1 WDR4 NUBP2	up	***
GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_DN	0.0000035	0.0001145	0.6272567	-0.3440858	-1.827752	179	CXCL3 LPIN2 ADPRH SOWAHC ZC3H12C FABP4 FYN RGS9 BAIAP2 MYD88 NUDT9 LMNA ANXA5 LITAF HDC FOXP1 SERPINB9 NDEL1 TIPARP MAP2K3 PTGIR RAB12 NPNT STX3 CDKN1A M6PR SLC6A6 ETF1 CD80 EBF2 ESD RAB8B STAT4 PTGER4 IFRD1 PIK3R1 CD83 SLC3A2 HIVEP2 EHD1 TGIF1 KCTD10 TEC ATP6V1A ATP6V0C GABARAPL1 GNA13 TSPO IST1 FKBP1A SF1 NBN SLC25A20 TRAF1 ULK2 NFKBIA ADORA2A MAFK CYTH1 TNFSF9 RORA LDLR	down	***
GO_CYTOKINE_METABOLIC_PROCESS	0.0001321	0.0024408	0.5188481	-0.3791313	-1.825419	92	EREG IL1A HMOX1 SPN IL1B TNFRSF8 CLEC7A HSPB1 GATA3 TRAF6 IL10 MAP2K3 PTAFR KLF4 TNFSF15 THBS1 NFKB1 PTPRC TLR4 SFTPD INHBA CD80 IL6 PSEN1 TYROBP	down	**
VERHAAK_GLIOBLASTOMA_PRONEURAL	0.0000407	0.0009123	0.5573322	0.4202053	1.824889	123	SLCO5A1 MCM10 SOX2 SCN3A TOX3 CLGN SRGAP3 E2F3 ARHGAP33 CDC25A FERMT1 DPYSL4 TMCC1 EPHB1 MPPED2 PODXL2 WASF1 PAFAH1B3 MYO10 FHOD3 SOX4 PFN2 RNFT2 TOPBP1 SOX11 PPM1E RALGPS1 CBX1 MAST1 DBN1 SPTBN2 ATAD5 MARCKSL1 CDC7 ZFP69B ERBB3 NRXN2 ZNF248 KIF21B GNG4 MARCKS GADD45G ZNF286A MMP16 FLRT1 ICK	up	***
BERENJENO_TRANSFORMED_BY_RHOA_UP	0.0000000	0.0000000	0.8266573	0.3689256	1.824566	484	HMGA2 TRIP13 FOXM1 HELLS KIF20A AK4 CDC45 MCM10 NGEF NUP107 NEK2 CCNB1 TIMELESS UBE2T GGCT SLC2A1 PRIM2 BRCA1 CDCA7 TTK RACGAP1 IQGAP3 E2F8 GTSE1 ANLN IGFBP6 SPP1 ASPM CDCA8 AURKB CENPA PTTG1 ECT2 CDC6 GAPDH FIGNL1 UHRF1 MCM4 MCM2 TYMS SLC4A4 MYBL2 PRC1 ORC1 CCNF EIF3B DTL CIB1 SPDL1 TNC TAMM41 NME1 RANBP1 RUVBL2 TNNT2 DNPH1 EXO1 CISD1 KIF23 LAMC2 MKI67 BUB1 TOP2A AURKA POLA2 SAE1 KIF2C MCM7 CDCA5 WDHD1 NSUN2 TOM1L1 KIF11 MCM3 CHAF1B CDC25C AIMP2 EMG1 FAM162A LIG1 TOPBP1 CHEK1 DNAJC9 ORC6 ACTL6A MAD2L1 AHCY FBL RAD51AP1 DCTPP1 MDM2 FLNB INCENP PON2 CKS1B NUSAP1 CBX5 ASF1B CDK1 POLE2 UCK2 BIRC5 CCT3 TNK2 GMNN POLR3K E2F1 PSMB5 DNA2 BPGM PSAT1 FEN1 EZH2 RAET1E CBX1 NOP2 DIAPH3 PA2G4 RNASEH2A KPNB1 EIF6 RANGAP1 HSPA4L NET1 DNMT1 TUBG1 DLGAP5 ADAM12 TACC3 KIF22 SSRP1 TK1 DTYMK PKP4 SAP30 POLD1 NUP85 TYRO3 HLA-A CCT7 CDC7 CENPV PSMB3 CDC20 RPRD1B LRRC59 FAM136A RPA1 CDR2 CKAP2 MCM5 ANKRD1 SNRPD1 HAUS6 SRSF1 DNAJC21 RCC1 CCNG1 PHC2 LSM4 TSR1 TCERG1 NUP62 MSH2 CCNA2 ADM PRIM1 BANF1 SNRPD2 MRPS25 RFC5 ABCF2 HK2 RAD51 TPGS2	up	***
GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN	0.0000136	0.0003618	0.5933255	0.4045149	1.824452	168	HJURP FBXW8 SLFN13 NEK2 MND1 PHGDH GINS1 CDK4 ANLN PLK1 CENPA MYBL2 PRC1 GJB7 AACS LIME1 ZWINT GOLPH3L CLPTM1L TMEM41A GOLPH3 KIF23 MKI67 TOP2A E2F2 PLXNA1 MAD2L1 AHCY TMED3 MRPL37 CDK1 GMNN PSMB5 SDR42E1 SEC61G RNF181 PSMC4 UBN2 GOLGA3 TUBG1 DLGAP5 PSMA5 MRPS34 PSME2 TMEM237 ASNS SIL1 KDELR3 STOML2 AAAS CLINT1 PRMT1 TMEM147 NDUFS7 KATNB1 MRPL51 CCNG1 CEP152 CCNA2 ECH1 BMP8B RDH10 ADRM1 PAICS GOLGA2	up	***
GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000033	0.0001070	0.6272567	-0.3436872	-1.824402	178	CXCL16 OLR1 DENND5A PTP4A2 GPR65 INSIG1 NEDD9 BCL2A1 HPS5 EDEM1 B3GNT5 SLC36A4 LATS2 BZW1 KLF10 TMEM41B SRGN TFRC TIPARP DIABLO ZMIZ1 MAP2K3 PLAUR SPAG9 NFKB1 CDKN1A GGTLC1 SIK2 ADIPOR2 OXSR1 PIK3R5 MAFF SNN NINJ1 RBPJ GZF1 ETV3 STAT4 CD83 ENTPD4 ATP13A3 SLC3A2 CDK17 RUNX3 AZIN1 ZBTB1 GPR84 SOD2 NBEAL1 ZNF267 PDE4B CCNH ICAM1 RLF IER5 RAB5A ZBTB25 TXNDC11 G3BP2 NFKBIA SAMSN1 DOCK4 DNAJA2 SPHK1 AFTPH	down	***
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_DN	0.0021545	0.0227273	0.4317077	-0.4440965	-1.823754	42	HMOX1 DYRK1A RGCC SLC25A37 PDGFA RHOB RAB12 PTPRC IRAK2 ATP6V0D2 CCL4 INHBA NINJ1 CD80 CCR1 VASH1 TRAF1 SERPINE1 TNFSF8 NR4A2 MAMDC2 ZFP36	down	*
GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN	0.0000034	0.0001109	0.6272567	-0.3426179	-1.823463	177	NLRC4 SLC31A2 MS4A7 PHACTR1 SOWAHC FABP4 CAT P2RY1 TMEM170B CAPN14 CITED2 AQP9 MYD88 SLC15A3 DNAJB14 CD36 STARD4 ADAM17 PPP1R15B CYB5A C1orf162 ITPRIP COQ10B KLF11 STK17B TLR4 DUSP1 ELK3 SLC6A6 OXSR1 IL7R BCLAF1 SMNDC1 DEGS1 BTG1 PDK4 CD80 RAB8B FOXN2 GSTO1 PTGER2 HSD17B12 GTDC1 CAP1 TOM1L2 FOS DDHD2 KCNA3 PDLIM5 MIR155HG CEP170 OPN3 NBN TFPI RTN4 CEBPD MEGF9 MMD THEMIS2 EIF4G2 CHML DCUN1D3 CMPK1 DRAM2 HEY1 MFSD1 GABPB1 SERP1 NMI	down	***
GSE6259_CD4_TCELL_VS_CD8_TCELL_DN	0.0000093	0.0002621	0.5933255	-0.3510165	-1.823271	160	SLC31A2 LPIN2 PPP4R1 DYRK1A TET2 SLC11A1 RFTN1 ARHGAP10 IFI30 STOM C1orf162 LAMTOR3 IL10 ITM2B ATP6V1D ATL3 CDS2 ATP6V0D2 FRMD4A CD300C DSE PEAK1 IL7R HTRA4 CD300LB SNN USP25 PRCP ARHGAP17 RNF149 BCAR3 SNAP23 PDCD6IP CD48 HPGDS RAB31 PDE5A GPR141 JAK1 STX7 CAP1 RIN2 PIK3AP1 GSAP DOK3 SMCR8 ZC3H12D STX12 KAT2B ICAM1 MOB3B CTTNBP2NL TIAM1 NUP98 KLRK1 FNIP2 THEMIS2 DOCK4 EHD4 IRF2	down	***
CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP	0.0000700	0.0014282	0.5384341	0.4311484	1.823070	103	FAM83B ENTPD2 KRT5 LAD1 EPN3 LCN2 PRR15L KRT16 SPINT2 KRT15 C6orf132 CBLC TRIM29 RNF43 SERPINA3 CD24 PDZK1IP1 PROM2 SPINT1 STEAP4 EHF GRHL2 DMKN EPHA1 ESRP1 GJB3 CDH3 MYO5B IRF6 ST14 PKP3 ELMO3 FXYD3 TMEM30B SSH3 RTKN OVOL2 TC2N PRSS8 CDH1 HOOK2 COX5B RHOD RAB25 KIAA1522 FGFBP1	up	**
RAMALHO_STEMNESS_DN	0.0016261	0.0183127	0.4550599	-0.4204034	-1.822816	56	ACVRL1 LY86 ST3GAL6 RTN3 MAL SLC11A1 BMP1 HDC PPP3CA SIRPA MPEG1 PTPRC CD53 EVI2A PPP2R5A CTSS TYROBP	down	*
GO_HISTONE_SERINE_PHOSPHORYLATION	0.0018427	0.0200752	0.4550599	0.7261855	1.822674	11	HMGA2 CCNB1 AURKB AURKA PRKAA2	up	*
GO_TERTIARY_GRANULE	0.0000401	0.0009014	0.5573322	-0.3608815	-1.822522	129	OLR1 CD55 LTA4H CLEC12A PTPRB OSCAR CHIT1 YPEL5 LAMP1 SLC11A1 RHOA CD33 ASAH1 PTX3 STOM LAIR1 SIRPA CD93 LAMTOR3 RAB14 CD58 CST3 PTAFR GAA CTSD ITGAX CD53 FCER1G HGSNAT NCKAP1L PRCP CTSS SNAP23 ATP11A STX7 ENPP4 SERPINB6 CR1 TIMP2 STXBP3 SIGLEC14 DOK3 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ADAM10	down	***
GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN	0.0000015	0.0000550	0.6435518	-0.3405927	-1.822335	186	IL1A SOWAHC GLIPR2 IL1B SNX10 MYADM MYD88 PLEKHA1 BCL2A1 IL1RN IER2 TRA2B MAP3K8 ZEB1 SRGN UBE2D3 PDGFA RHOB IL10 MSR1 STAT5A RAB12 PLAUR VASP NFKB1 CDKN1A CXCL2 SELP CCND2 CD53 DUSP1 N4BP1 KPNA3 PROCR RNF149 SOCS3 INPP5B MTMR14 MAP4K4 JUNB IFRD1 ATP13A3 ACSL1 AGFG1 GPR3 RHOQ PELI1 YTHDF3 PBRM1 EHD1 NAB1 IFNAR1 PIM1 STK40 LTBP1 ETS2 IST1 ICAM1 SLC31A1 SERTAD1 CEBPD HSP90AA1 HNRNPK SRSF10 MCOLN2 TNFSF9 SPATA13 HNRNPH1 HERPUD1 SERPINE1 CLEC4E PIAS2 KCMF1 TES DLD FNDC3A PDPN PTGS2 HIVEP1 JARID2 NFKBIZ RNF19B	down	***
SHEPARD_CRUSH_AND_BURN_MUTANT_DN	0.0000217	0.0005376	0.5756103	0.4122234	1.822298	143	FOXM1 PARPBP BUB1B CCNB1 TOX3 PRIM2 PIF1 TTK CDCA2 RACGAP1 GTSE1 KIF14 ANLN ASPM AURKB ECT2 DIO2 TPX2 CCNB2 GOLGB1 PRC1 CEP250 MELK KIF23 CEP55 MKI67 AP4M1 LGMN MYO10 KIF2C KIF11 MDK SOX11 HES6 PON1 CDK1 BIRC5 NEIL3 ARNT2 DLGAP5 TACC3 LMNB2 HMGN3 TK1 TUBA8 CHD5 ARHGAP12 KDM3A CDC20 HMGA1	up	***
GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_DN	0.0000060	0.0001809	0.6105269	-0.3464343	-1.822166	164	LPIN2 SWAP70 SNX10 CD44 MYADM SFR1 GNPTAB ZEB2 ANXA1 ARHGAP10 ARSB ENTPD1 ZDHHC2 SERPINB9 LAIR1 NR4A1 IL18R1 MPHOSPH6 SRGN BAG1 AHNAK CASP1 YBX3 CLIC4 CCL3 ITGAX HOPX ID2 CCL4 PRF1 PLEK DSTN INSL6 CALM2 CD80 CD48 CCDC50 IFNGR1 DAPK2 COBLL1 TBX21 TIGIT SLC25A24 NKG7 KLRC2 PIK3AP1 SMPDL3B CHPT1 GSAP DUSP5 ATXN1 GABARAPL1 PHF11 NPTN GEM IL18RAP	down	***
GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN	0.0000101	0.0002812	0.5933255	-0.3471785	-1.822146	165	KMO SIDT2 SWAP70 HHEX SIK1 FIG4 LY86 CORO1C MEF2A CD1C CD22 FAM49A FGR GGA2 SLC7A7 GM2A MAP3K8 IFI30 MS4A1 GNG7 GRN TUBB6 CD37 TBC1D9 PIP5K1B YBX3 DENND3 CLIC4 HLA-DQA1 HCK PRCP SNX3 PKIG RAB31 STX7 IRF8 GRB2 COBLL1 IGKV3-20 CDK14 PLCG2 RHOQ CD74 TFEB TCF4 CD1D VPREB3 PDLIM1 CBFA2T3 CD86 KYNU TAGLN OPN3 SPIB ITGAE SCPEP1 METTL7A CD19 EHD3 BANK1 CSF2RB CTSH BHLHE41	down	***
GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_UP	0.0002043	0.0034985	0.5188481	0.4420468	1.822002	82	HMGA2 UNC5CL TG CHRNG FOXE1 TSPYL5 STK31 CHRNA7 SIX1 RUNDC3A TRIM29 SLC16A8 CSRNP3 RSPO4 C7orf50 GAS8 LINGO1 SPAG6 SDCBP2 KY MMP7 TAC4 ANKRD1 EDAR TMEM17 YBX2 PAK4 NPTX1 FAM78B DPP10 ASCL2 TMEM169 CHMP6 ACSBG1 CRYGS LRIT3 HMG20B C1orf194 WIPF3	up	**
chr11q12	0.0001077	0.0020601	0.5384341	-0.3709899	-1.821841	100	MS4A7 RN7SL23P LPXN WDR74 MS4A15 TMEM138 SLC15A3 CD5 BEST1 MS4A14 CYB561A3 MED19 MS4A1 LRRN4CL SNHG1 AHNAK MPEG1 STX3 HNRNPUL2 BTBD18 CNTF NXF1 ZFP91 STX5 SLC3A2 DAGLA FABP5P7 CD6 SNORA57 MS4A4A TMEM109 TMX2 ZDHHC5 MS4A2 SDHAF2 FADS3	down	**
ZWANG_CLASS_2_TRANSIENTLY_INDUCED_BY_EGF	0.0020324	0.0216984	0.4317077	-0.4457356	-1.821336	41	CLIC3 CITED2 CDC42EP2 ARHGAP29 CLCF1 LIFR KLF10 GLS RGCC CLK1 PXDC1 JAM2 INHBA GLIPR1 RNF24 GFPT2 TAGLN OSR1 HSPA8 SPHK1 EGR1 CHIC2	down	*
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN	0.0000042	0.0001349	0.6105269	-0.3428647	-1.821266	179	SASH1 USP12 OTUD1 LMO2 BACH1 NEDD4L AQP9 SFR1 BCL2A1 IL23A TNFRSF8 SLC7A7 MTF1 C1orf21 TNIP3 KLF6 PTX3 HLX SLC25A37 TFRC CASP5 IL10 SAP30BP REST FBXL3 PDE8A ATL3 P2RY2 CXCL2 IL7R HES1 TP53BP2 IL24 KANK1 HCAR3 FLT1 IL6 SOCS3 PIKFYVE ETV3 STAT4 MAP4K4 WTAP FERMT2 ENPP4 PNPLA8 SIGLEC15 FSD1L GTDC1 GFPT2 AGFG1 PELI1 SLC22A1 PIK3AP1 SERPINB1 FPR2 PIM1 ANKLE2 TNFAIP8 MIR155HG MGAT2 IER5 CDC42EP3 TRAF1 RND1 PLGRKT MAP3K4 PTEN B3GNT2 THRAP3 SAMSN1 TRIM36 PAPSS2 CSF2 SLC16A10 FJX1 SVIL HMGCS1	down	***
GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP	0.0000059	0.0001775	0.6105269	-0.3440919	-1.821115	169	IL1A SIK1 EGR2 CCRL2 FLVCR2 ESAM WWC2 PTPRM HBEGF LATS2 BTG2 CYYR1 NR4A1 TNS1 CD93 SPRY2 PDE4D CSRNP1 TSPAN12 PLAUR FAM76A ID3 OSTF1 THBS1 CXCL2 ATF3 UXS1 PER1 DUSP1 MAFF RASGEF1B FOXN3 SLC25A33 SLC25A25 CREM SGK1 SLCO2B1 JUN OXNAD1 ARL5B PLK3 JUNB RCAN1 PPP1R15A ACKR3 HOMER1 CD151 FOS SPRY4 FOSB ZFYVE9 DUSP5 TGFB1I1 ADPGK SLC10A6 ETS2 GEM CEBPD DAPK1 EDN1 TMCC3 JDP2 KALRN EGR1 SERPINE1 DUSP6 NR4A2 ARL4D ZFP36 VSTM4 ANGPT2 ADHFE1 AKAP12 TNFSF18 TRIM25 NR4A3 PTGS2 NTF3 RNF19B	down	***
GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0000035	0.0001128	0.6272567	-0.3423742	-1.820397	175	OLR1 DENND5A CLDND1 TBC1D2 HPS5 TRIB1 ZEB2 PTS SLC36A4 PPP1R15B BZW1 GPBP1L1 NR4A1 NFE2L2 LAMTOR3 HNRNPU RNFT1 MAP1LC3B SPAG9 GGTLC1 CXCL2 IRAK2 PNRC1 ADIPOR2 OXSR1 FKBP15 SNX3 RBPJ PPIL4 ETF1 RYBP GABARAPL2 RAB8B ARL5B SH3BP5 NSMCE2 PTGER4 HSPA13 OSM MALT1 TPRA1 SLC3A2 AKIRIN2 NDUFA5 ADPGK CRY1 RXRA ICAM1 TTC21A NUP98 G3BP2 GLUL NFKBIA EDN1 ZDHHC5 DNAJB9 ANXA11 RABGEF1 SERPINE1 HMGCS1 ATF2 ING1 CCNK ZNF654 CD69 CCDC93	down	***
GO_CENTRIOLE_CENTRIOLE_COHESION	0.0033480	0.0317843	0.4317077	0.6994808	1.820295	12	NEK2 CEP250 ODF2 CROCC	up	*
GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP	0.0000122	0.0003314	0.5933255	-0.3536604	-1.820260	151	SLC31A2 MS4A7 FBP1 TUBB1 EGR2 SAMHD1 STX11 RXFP1 LAMP1 ASAH1 CHMP1B NAAA LITAF PRSS12 STOM C1orf162 GPBAR1 TCF7L2 CST3 RHOB ZFAND5 ATF3 PLEK KLRD1 MBD2 VAMP5 INSL6 CALM2 CMTM6 FAM102B SRGAP2C ARL6IP5 CREBRF FMNL2 SCEL IL6 RGS18 GLUD1 RHOG IQSEC3 SUCNR1 MOB1A AGPS ALDH3B1 PIK3AP1 NPTN ARPC2 CDKN1C CALCOCO2 S100A4 COMMD8 CTSC PDE4A FNIP2	down	***
MORF_RFC4	0.0000275	0.0006519	0.5756103	0.4171923	1.820215	126	TRIP13 BUB1B NDC80 KIF14 ESPL1 MCM2 TYMS SRPK1 SHMT2 XPOT ZWINT RUVBL2 HMMR CHAF1A SDHA BUB1 TOP2A CCT5 PRKDC TRRAP RAD54L MCM3 DNAJC9 ACTL6A CAD ALG3 SSBP1 GOT2 UNG PMEL SPAG5 KXD1 DNMT1 ILF2 SNRPA SSRP1 MLEC TCEA1 DNAJC11 RPA1 MCM6 SRSF1 MSH2 CCNA2 DOCK3 VDAC1 SNRNP200 VDAC3 ZNF131 MRPS27 GPN1 LYPLA1 AKR7A2 DGUOK TNPO3 SAFB CS NAE1 HNRNPAB LRPPRC	up	***
GO_MIRNA_MEDIATED_INHIBITION_OF_TRANSLATION	0.0061018	0.0496369	0.4070179	-0.5669116	-1.820040	18	TRIM71 MIR27B MIR146A RBM4 AGO4 AGO3	down	*
GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP	0.0000014	0.0000508	0.6435518	-0.3449535	-1.820039	171	SEMA6B EREG PID1 BCL2A1 SLC11A1 ATP2B1 CARD16 MCTP1 SIRPB2 ASAH1 SWT1 CAMTA1 SLAIN2 TOR1AIP1 TCF7L2 TMEM38B FBXL5 PTPN12 AGO3 PPP6R3 LIMS1 BST1 PLAUR DAB2 MAFG LAPTM5 ARAP3 TM6SF1 ALOX5AP PINK1 FKBP15 IL24 MAPRE2 KREMEN1 CNRIP1 STK24 FLT1 DDX60L KIF13A PDCD6IP SERPINB8 SH3BP5 MED30 CARD8 TMEM251 PNPLA8 YWHAZ SNX9 RUNX3 MYL12A VAV3 TGIF1 TSC22D1 CCL20 BNIP3L ATP9B C7orf31 BCAT1 RAB2B DAZAP2 CHIC2 DUSP6 LINC00922 SLC19A2 PRKCH ICOS SH3GLB1 SLC38A2 YRDC	down	***
MORI_PRE_BI_LYMPHOCYTE_DN	0.0003700	0.0058267	0.4984931	-0.3957030	-1.819935	73	LY86 SAMHD1 GPCPD1 S1PR1 CD22 CASP9 BTG2 MS4A1 CLK1 MCL1 NFKB1 PTPRC AKIRIN1 BTG1 RBM39 ATP6V0B FBXO11 RHOQ KLF2 MYL12A CD74 IAH1 CNR2 ZFP36 CD79B FCRLA CCNDBP1 PNRC2 JARID2 NFKBIZ FAM107B IL10RA CYTIP TANK TMEM71 ADCY7 LSP1 BLK RIOK3	down	**
MIR25_3P	0.0000000	0.0000005	0.7614608	-0.3159974	-1.819690	358	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 MED19 SLC7A11 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 KBTBD8 MORC3 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 ZNF521 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 MEF2D ZFYVE21 ITGA6 ROBO2 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1 NFYB MYO5A ADCY3 ANKRD44 ADAM19 MFHAS1 SLC24A3 PNISR PSMD14 KLHL29 PIK3R3 RBM27 ANKRD28 ZC2HC1A AIDA GTF2A1	down	***
chr5q34	0.0018271	0.0199311	0.4550599	0.7682150	1.819166	9	ATP10B TENM2 HMMR WWC1 GABRB2 CCNG1	up	*
GO_REGULATION_OF_MEMBRANE_REPOLARIZATION_DURING_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.0008016	0.0107147	0.4772708	0.8633112	1.819137	6	NOS1AP DLG1 KCNE3 RNF207	up	*
GO_REGULATION_OF_LYMPHOCYTE_MIGRATION	0.0011823	0.0144812	0.4550599	-0.4216966	-1.819096	53	GCSAML ADTRP SPN RHOA APOD ADAM17 CRK CCL3 CCL4 JAM2 XCL2 OXSR1 LRCH1 DOCK8 MIA3 KLRC4-KLRK1 ADAM10 CCL20 CCR6	down	*
GO_ORGANELLAR_RIBOSOME	0.0004210	0.0064022	0.4984931	0.4421521	1.818801	80	MRPL46 MRPS35 MRPL15 MRPL3 MRPL27 MRPS11 MRPS30 MTG1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 CHCHD1 C12orf65 MRPL24 MRPS33 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPL55 MRPL9 MRPL21 MRPS27 MRPL20 MRPL48 MRPS26 MTG2 MRPS16 MRPL12 MRPL43 MRPL2 MRPS6	up	**
GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN	0.0000167	0.0004334	0.5756103	0.4043858	1.818718	161	CA9 CDCA7 FLAD1 ALDH18A1 SPATS2 COCH GLDC MIS18A ZWINT UQCC1 CLPTM1L RPAP1 KIF3B IGLV1-44 MCM7 RRM2 MCM3 SEC61A1 MCCC2 KDELR2 ZKSCAN1 BLM MRPL37 PKD1P1 TCTN2 POU5F1B MRPS12 METTL3 TRAPPC12 ZNF692 PABPC1L GNPAT PDCD11 IGLV6-57 SLC26A2 MAMSTR CCT7 KLHDC3 MRPL24 MED24 PIGU HAX1 PDIA4 PPP1R3E PMS1 HDLBP ECH1 TYSND1 AURKAIP1 UQCRQ MTHFD1 IGLV3-19 SETD5 TFB1M CD38 APEH MRTO4 NSUN5 DGUOK MAP3K12 ALG6 HDDC3 CYSLTR2 MEN1 SLC44A1 OIP5 HM13 NSUN5P1 C11orf24 NVL DDB1 FKBP2 ST6GAL1 METTL5 NDUFB10	up	***
GO_CHROMATIN_REMODELING	0.0000415	0.0009238	0.5573322	0.4146624	1.818139	129	HMGA2 TP63 HELLS HJURP RUVBL1 CENPA SOX9 MIS18A RUVBL2 SMARCD3 SMARCC1 FOXA1 CENPL CBX3 TPR CENPW MORC2 ZNHIT1 ACTL6A CENPO PIH1D1 TADA2A PAK1 CENPH NPM3 VPS72 CENPP PABPC1L SATB2 CENPQ HDAC1 ANP32E CHD5 ESR1 CENPK BAZ2A CENPV CENPM HMGA1 KDM4B CENPT SMARCC2 SUV39H2 SMARCA4 INO80E CHD3 SIRT6 SRCAP KDM5B SMARCB1 ACTR5	up	***
GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_DN	0.0000038	0.0001226	0.6272567	-0.3435126	-1.817978	172	CLIC3 DENND5A OSBPL1A CD55 HHEX MNDA SIK1 FXYD2 DNASE1L3 ZEB2 SH2B3 MAN2B1 GM2A LITAF CD93 GRN TFEC TPP1 LY96 CD302 FCER1G ALOX5AP GLB1 ARHGAP17 KANK1 CTSS UTRN STAT4 KCTD12 ST6GALNAC4 TYROBP PPP1R15A STX7 GLIPR1 IRF8 GPR183 MFAP4 RPS6KA1 TNFSF13 FOSB CD74 TCF4 PEA15 MILR1 SERPINB1 BAZ2B ACYP2 RGS2 OPN3 IQSEC1 SPIB MS4A4A ALDH2 GPD1L TMEM184B CTSC DUSP7 THEMIS2 RSU1 FEZ2 HERPUD1 CSF2RB CTSH	down	***
GO_NEURON_FATE_SPECIFICATION	0.0019950	0.0213967	0.4317077	0.7240928	1.817421	11	MNX1 EYA1 SIX1 FOXA1 ESRP1	up	*
GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_UP	0.0000247	0.0005947	0.5756103	0.4109504	1.817411	141	LTF TRIP13 CDC45 BRCA1 LCN2 TTK KIF14 POLE PLK1 NUF2 CDCA8 CENPA ECT2 TPX2 PRC1 NUDT1 TOP2A CLSPN KIF11 CHAF1B LIG1 CHEK1 DNAJC9 MAD2L1 SPC24 INCENP CKS1B NCAPG2 CBX5 CDK1 CENPH BIRC5 JAKMIP1 NCAPG NEIL3 DLGAP5 TACC3 KIF22 HDAC1 ANP32E IGHM PPP1R8 RPA1 GMPPA MCM6 CD2BP2 SUOX CCNA2 RAD51 COX5B ARHGAP11A UQCRQ RPN1 SEPHS1 TTC9C PIGQ TRPC4AP ACSL5 COPE PLAC8 PRRC1	up	***
WAGNER_APO2_SENSITIVITY	0.0017365	0.0191685	0.4550599	0.6017161	1.817214	22	FUT6 GALNT14 GALNT6 FUT3 GALNT10 GALNT9 FUT2 POFUT1 GALNT3	up	*
GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP	0.0000039	0.0001260	0.6105269	-0.3430007	-1.817208	173	EPAS1 PECAM1 RBMS2 GIMAP8 TRPV2 SH2D3C IDI1 NUDT9 MKNK1 TMX4 RBM7 KLHL30 B3GNT5 HBEGF ARSB C1orf21 PBX3 PAQR3 SERPINB9 HERC3 BAG1 CD37 ZYG11B RHOB EIF1B ZADH2 FAM49B RIT1 COTL1 CTBS PTGER3 TM6SF1 ANXA3 ADD1 MYLIP TECR AREG ASNSD1 EBAG9	down	***
GO_SYNAPTONEMAL_STRUCTURE	0.0017365	0.0191685	0.4550599	0.6016118	1.816898	22	BRCA1 PLK1 STAG3 REC8 SYCP2 HORMAD1 BLM INCENP	up	*
WINTER_HYPOXIA_DN	0.0022156	0.0231811	0.4317077	-0.4423698	-1.816663	42	LMO2 ABCB1 FLI1 EVI2B PTPRC EVI2A NCKAP1L ARL6IP5 SYNPO2 CD48 IRF8 GYPC CELF2 ICAM2 GIMAP1 CHPT1 PARM1 SLC25A20 ISCU IL16	down	*
GO_REGULATION_OF_WOUND_HEALING	0.0000714	0.0014534	0.5384341	-0.3597856	-1.816374	117	AJAP1 ADTRP WFDC1 WNT4 THBD CAV1 TBXA2R HMGCR CD9 TGFBR2 CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 CLEC7A ANXA5 NFE2L2 CRK PDGFA FOXC2 PLAUR THBS1 CDKN1A SELP HPSE TLR4 FCER1G PLEK UBASH3B KANK1 DUOX1 ENPP4 PRKCE CD34 SRSF6 EPPK1 TEC CLASP2 FGF2 TFPI CXCR4 EDN1 PTEN PRKG1 ANO6 SERPINE1 CDKN1B	down	**
BIOCARTA_RANMS_PATHWAY	0.0018271	0.0199311	0.4550599	0.7669993	1.816288	9	TPX2 RANBP1 KIF15 AURKA KPNB1 RANGAP1 RCC1	up	*
HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP	0.0000009	0.0000343	0.6594444	-0.3327116	-1.816216	218	EPAS1 CXCL3 EREG IL1A OLR1 CD55 IL1B FYN NEDD4L FOSL1 MYD88 SLC39A8 S1PR1 ALAS1 BCL2A1 PPM1D IER2 RBM7 RRAGC EIF1 PTX3 ZMYM6 GRN ARHGEF2 FBXL5 EIF1B EVI2B YBX3 ACSL3 PLAUR VRK2 LY96 CTBS PNRC1 DUSP1 EVI2A ANXA3 HEXB PROCR IL6 CREM DCTN6 SOCS3 SNAP23 PIKFYVE JUNB IFNGR1 IFRD1 LYRM1 AGFG1 PELI1 KLF2 MME SERPINB1 TGIF1 VAMP4 SOD2 STON1 RGS2 CLEC2B PDE4B ETS2 TNFAIP8 EPN2 TAB2 RIPK2 EPHA2 MTUS1 CYTH1 DOCK4 EHD4 PMAIP1 IRF2 ARHGEF18 HTRA2	down	***
KORKOLA_TERATOMA	0.0013107	0.0156784	0.4550599	0.5231202	1.815598	36	TSPAN8 PLAT CCNB1 LCN2 DNMT3B NUF2 CENPA AGR2 ZWINT AURKA EHF FEN1 DLGAP5 CDC20 MCM5 LRRC17	up	*
GO_POSITIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY	0.0034073	0.0322721	0.4317077	0.6976538	1.815540	12	PAGR1 FOXA1 PPP5C SKP2 PARP1 PAK1	up	*
GO_TRANSLATIONAL_TERMINATION	0.0003924	0.0060865	0.4984931	0.4293563	1.814844	96	MRPL46 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 MRPS30 GLE1 MRPL36 MRPL37 MRPS2 MRPL17 MRPS12 MRPS34 MRPL11 MRPL52 JMJD4 MRPL4 DAP3 GFM2 CHCHD1 C12orf65 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 MRPL14 MRPS25 MRPL55 N6AMT1 GADD45GIP1 MRPL9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 APEH MRPS16 MRPL12 MRPL43 MRPL2 MRPS6	up	**
GUILLAUMOND_KLF10_TARGETS_DN	0.0047018	0.0407970	0.4070179	-0.5087403	-1.814183	25	GPD1 FCN1 AQP9 CYB5R3 TXNIP CD36 CTSS SRSF3 RCAN1 CHPT1 RTN4 PSME4 PAPSS2	down	*
GSE25677_MPL_VS_R848_STIM_BCELL_UP	0.0000105	0.0002902	0.5933255	-0.3490410	-1.814163	155	CD300LF ABHD5 PDLIM2 ZC3H12C PGC RUNDC3B PLEKHA1 S1PR1 RXFP1 CD9 FUCA1 EDEM1 CD36 PLA2G7 GM2A MS4A14 MS4A1 LAIR1 C1orf162 GRN PDE4D HERC3 PER3 TBC1D9 PLBD1 FMNL3 PDE8A UBE2E2 ID2 UXS1 CARS2 DSE MATK RUFY3 RASGEF1B HCK BCAR3 UTRN TYROBP ACKR3 LPCAT2 NDST1 TCF4 NAB1 CD86 ATXN1 CD81 CCR1	down	***
GSE27786_CD4_TCELL_VS_NKCELL_DN	0.0000049	0.0001543	0.6105269	-0.3413924	-1.813445	179	SNX10 MIR22HG APIP MSRA MKNK1 TET2 HPS5 SCARA3 GGA2 KIAA0355 NFIX ARSB C1orf21 MAP3K8 PICALM ADIPOR1 TOR1AIP1 SPRY2 CRTAM TMEM38B EPB41L2 LRP4 PTPN12 BNIP2 ITM2B PLEKHM3 TMED5 FMNL3 PTPRC CTBS PAPSS1 TM6SF1 PRF1 KLRD1 PPP2R5A SLC6A6 TM9SF2 HES1 HEXB CDC40 SNAP23 OASL ARL6IP6 LIMD1 ATP6V0B VPS26A UBAC2 SMU1 MBNL2 FAM43A ATL2 REL YWHAZ ATG3 RIN2 TFEB CRYZL1 GEM CPQ ITPRIPL2 RTN1 TOB2 ITCH NABP1 MAPKAP1 NIPSNAP3A CYBA UBAP1 PHYH FHL5 CHML CMPK1 ARL4D FAR1 YWHAB	down	***
GO_NEGATIVE_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION	0.0047389	0.0410084	0.4070179	-0.6224689	-1.813268	13	CALCRL ADRB2 KCNMA1 RGS2 PRKG1 DOCK4 DOCK5 PTGS2	down	*
GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN	0.0000103	0.0002847	0.5933255	0.3972813	1.812920	183	TRIP13 PSPH PRIM2 BRCA1 ANLN NDUFS6 IFT27 ACAD9 ALDH18A1 MCM2 CCT6A XPOT TAMM41 NUDT1 CISD1 KIF23 MKI67 TOP2A POLD2 LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD CNPY2 CKS1B NUSAP1 MRPL37 CDK1 BIRC5 CCT3 GMNN POLR3K MRPL17 TSPAN31 EZH2 CBX1 NOP2 TPD52L2 TUBG1 TACC3 MNS1 TRIM37 DUSP12 NUP85 RAD50 CENPK CKAP5 CDC20 RPRD1B RRP9 RPL7L1 CKAP2 MCM5 HAX1 RCC1 PDIA4 HAUS4 RFC5 NME4 PDAP1 WDR77 INO80E HK2 PGAM1 SPR RPN1 POLR1A DDX52 CHERP DTD2 DDX41 CYB5B RCN2 MRTO4 LUC7L3 SRM PLK4 HRAS MRPL2 COQ5 GCSH ABCD3 PPA1 TIMM9 CRCP MTHFD2 POLD3 CTPS1 ACOT7 NUDT19 HMBS	up	***
MA_MYELOID_DIFFERENTIATION_DN	0.0024478	0.0249878	0.4317077	-0.4718461	-1.812376	35	PDE1B CITED2 NFATC3 PLA2G7 HBEGF CES1 ZFAND5 RBPJ YBX1 STAT4 NOTCH1 FOS GNA13 HSPA2 KIF1B SMAD4	down	*
ZHANG_RESPONSE_TO_CANTHARIDIN_DN	0.0010509	0.0132062	0.4550599	0.4629928	1.812001	60	CDK4 SLC27A2 EIF3B RUVBL2 POLD2 MCM7 RRM2 MRPL3 ERCC2 HARS2 TRAP1 PA2G4 POLR2H FANCG RHOC TUBG1 SNRPA SUPT16H SNRPD1 FARSA PRIM1 RFC5 FARSB PGAM1 MTHFD1 SNRPC NDUFB2 PFKL CTPS1 EEF1D GTF3A RPSA ZNF200 IDH3A TIMM23	up	*
GCM_DEAF1	0.0032502	0.0310282	0.4317077	-0.5001972	-1.811893	26	RAPGEF2 KIAA1109 DNAJB14 RAB14 MOAP1 UBQLN1 NAPG DDHD2 G3BP2 TMEM184B FOXJ2 TMEM30A GPR153	down	*
GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN	0.0000267	0.0006380	0.5756103	0.3986255	1.811776	178	KIF20A PARPBP GINS1 SNF8 ESPL1 ACOT8 TPX2 CCNB2 GOLGB1 RBBP8 PRC1 MYL6B DCTN2 NME1 MELK EXO1 CISD1 RPL39L KIF15 KNTC1 BUB1 CCT5 AURKA KIF2C MCM7 COASY RRM2 PLTP TARS2 KDELR2 BLM TST ALDOA PARP1 CKS1B NUSAP1 TMEM106C CBX5 BIRC5 C1orf112 POLR3K NEIL3 FEN1 EZH2 MRPS12 IGSF3 LAPTM4B SNRNP25 DPP3 FAH PSMA5 MLEC FHL2 CDC7 DHTKD1 LIMA1 CDC20 ORMDL2 MCM6 PPCDC TDP1 LSM4 ATAD2 NUP62 RFC5 WDR77 RAD51 UQCRQ CENPE MTHFD1 PAICS PPIA BCAT2 RAD1 DDB2 DNM1L ILVBL IFI16 AKR7A2	up	***
HALMOS_CEBPA_TARGETS_UP	0.0039702	0.0360357	0.4070179	-0.4370906	-1.811701	43	CXCL3 HMOX1 BMP2 FOLR1 FOXA2 PTX3 CXCL2 ARL4A BTG1 HCAR3 RGS2 ETS2 CCL20 BMP2K TNFAIP8 EPHA4 MEGF9	down	*
LU_AGING_BRAIN_UP	0.0000003	0.0000124	0.6749629	-0.3309742	-1.811407	230	PECAM1 GREB1 PTP4A2 RDX HSD17B6 GPC5 FYN CAV1 QKI S1PR1 MAL TGFBR2 ZEB2 TXNIP APOD SEMA3B RAPGEF4 CSRP1 PICALM ANXA5 LITAF ABCG1 RNASE1 CAV2 STOM TOR1AIP1 TMEM123 NFE2L2 SFRP1 CLK1 TIPARP LRP4 KDSR TLE4 AHNAK SCP2 ZCCHC24 ZNF423 CLDN5 EPM2A CLIC4 VIM CD302 PIK3C2A WFS1 TP53BP2 AFF1 ANXA3 VWF TOPORS KANK1 VAMP3 ID4 NEK7 SNAP23 VAT1 SLC14A1 FERMT2 PODXL FRYL RASSF2 ICAM2 MYL12A RIN2 PHF3 TGIF1 BAZ2B HNRNPH3 TOB1 LTBP1 CLEC2B RBL2 HSPA2 FGF2 PDLIM5 CEP170 NT5C2 CEBPD PIP4K2A PARVA METTL7A NFKBIA	down	***
NAKAMURA_LUNG_CANCER	0.0011212	0.0138787	0.4550599	0.8171525	1.811281	7	ATP10B TFPI2 SCG5 TOP2A AURKA COL11A1 MCM6	up	*
GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_DN	0.0003253	0.0052113	0.4984931	-0.3931076	-1.811181	74	CXCL3 IL1B MIR22HG CD44 ERG ANXA5 HLX IL18R1 SPTBN1 TCF7L2 PTPRC CXCL2 SELL EVI2A INHBA HLA-DQA1 AREG CREM SH3BP5 RABGAP1 PTGER4 ENPP4 GLIPR1 IDS TCF4 TGFB1I1 SOD2 CLEC2B TFPI LIMCH1 FNBP1 DUSP6 SVIL	down	**
GSE3982_BASOPHIL_VS_NKCELL_UP	0.0000128	0.0003446	0.5933255	-0.3450492	-1.810971	165	KRT81 EREG OSBPL11 LYL1 BACH1 MYD88 NTM MANBA ANXA1 WWC2 NDUFAF1 NLK SPTBN1 UBE2D3 MCL1 FLI1 FBXL5 SDCBP KIAA0513 FAM124B UHRF1BP1L TM6SF1 TM9SF2 ACTR2 RAB6A BTG1 ZCWPW1 AREG BCAR3 PPP6C RAB31 GSTO1 LYRM1 YWHAZ NDUFV2 PTP4A1 NOP10 RBKS MARC2 AZIN1 CHPT1 MIA3 CNOT7 PIM1 UTP3 CCR1 ADAM10 SERINC3 PDLIM5 TNFAIP8 LMOD1 TPT1 LRP12 CYB5R4 ESYT1 NLRP3 GLUL MARC1 C21orf91 DAZAP2 GRB10 EID1 SVIL CRBN OSGIN2 TREM2 SH3GLB1 ZNF654	down	***
GO_VENTRICULAR_SEPTUM_MORPHOGENESIS	0.0028596	0.0280520	0.4317077	-0.4430789	-1.810789	40	TBX3 CITED2 BMPR2 TGFBR3 TGFBR2 ID2 SMAD7 HES1 MIR17HG TGFB2 RBPJ NOTCH1 WNT11 SAV1 ZFPM2 SMAD4 NOG HEY1 WNT5A ROBO2	down	*
CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN	0.0002941	0.0048067	0.4984931	0.4366121	1.810446	86	FOXM1 CDC45 TROAP CCNB1 TRAIP AURKB CENPA PTTG1 CDC6 TPX2 CCNB2 MCM2 CCNF SMARCD3 MKI67 AURKA KIF2C MCM7 MCM3 RAD51AP1 DCLK1 CKS1B CDK1 EZH2 RECQL4 COL1A2 DLGAP5 TK1	up	**
GO_MICROTUBULE_BASED_PROCESS	0.0000000	0.0000000	0.8753251	0.3603444	1.810256	632	KIF1A PKHD1 KIF12 MCIDAS KLC3 CEP72 SPICE1 KIF20A MDM1 DNAH2 AP3B2 CHEK2 NEK2 CCNB1 UCHL1 KIF18B NDC80 BRCA1 STK36 TUBB2B TTK RACGAP1 BRSK1 GTSE1 IFT122 KIF14 SPAG17 ASPM STIL MSTO1 TTC26 CEP70 PLK1 NUF2 IFT27 AURKB CENPA ESPL1 TPX2 GAPDH FIGNL1 MYBL2 DNAH3 PRC1 EFNA5 XRCC2 CCNF DYNC1I1 CIB1 KIF27 DNAH14 DCTN2 SPDL1 DNAI1 HAUS5 RANBP1 CEP250 WDR62 RSPH1 ARMC4 DLG1 MAP7 KIF23 CUL9 SPAG16 CUL7 BICD1 KIF15 COPG2 COPG1 KIF3B CCDC13 AUNIP MAP10 AURKA ODF2 IFT43 TPR KIF2C CENPW POC1A HYDIN WDR78 DPCD TEKT2 FSD1 HOOK1 CCDC114 WDR73 KIF11 GPSM2 BLOC1S1 WDR66 WDR60 NME5 DNAH8 CHEK1 IFT172 MAD2L1 GAS8 KIF3C CLIP3 DNAAF3 DNAH11 C2CD3 TRPV4 SPRY1 PARD3 CCDC40 PSRC1 MARK1 CCDC78 KNSTRN DRC1 NUSAP1 PAK1 KIAA0556 LRGUK LRRC6 CDK1 CROCC DNAH6 CEP97 KIF5A CENPJ BIRC5 AP3D1 KIAA0753 SUN1 KIF19 KIF2A KIF7 SSX2IP CCDC88C DYNLL2 SPAG5 SAPCD2 LCA5 DNAH5 PRKAA2 FGFR1OP IFT52 KPNB1 VBP1 CEP63 SPEF1 CEP192 TUBG1 DLGAP5 SPG7 DNAH7 NINL TACC3 LLGL2 CCDC151 TUBB2A TUBA3D KIF22 IQCG TRIM37 TUBA8 KIF21A SPAG1 MAP6D1 KIF20B TEKT3 SPA17 TRAF3IP1 DNAJB13 KLC2 SASS6 CKAP5 CDC20 WDR34 TUBG2 AAAS TTLL3 EFHC1 AP3M2 CHMP4C CDK5RAP2 DYNC1LI2 KIF21B CKAP2 DNAI2 WDR35 HAUS6 DYNC2H1 STMN3 KATNB1 SKAP1 TTLL6 RCC1 HAUS4 RSPH4A NEFH CEP152 CNTN2 NUP62 CEP85 CATSPER1 ALMS1 APC2 ULK4 NTMT1 NAV1 TUBGCP4 SYBU ICK CLUAP1 DNAH1 HOOK2 TUBA4B CCDC88B CHMP1A MARK4 TRAK1 CHMP2A CHD3 CDK5 LLGL1 RHOT2 CELSR2 ERBB2 BCAS3 MAPK8IP3 CAMSAP3 CENPE DTNBP1	up	***
GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN	0.0000068	0.0002005	0.6105269	-0.3420208	-1.810154	169	HMOX1 LRRC8C DCSTAMP BACH1 CORO1C BAIAP2 SLC25A30 FXYD2 STX11 NCF2 CD9 AGPAT4 ACER3 AVPI1 ANXA1 STARD4 SPG21 PICALM LUZP1 LITAF KLF6 SLC7A11 TMEM123 ATP6V1H TBC1D9 ITPRIP SDCBP VIM HPSE ACTR3 ALOX5AP UBASH3B HLA-DQA1 CMTM6 ZDHHC20 SOCS3 RAB8B HCST CD48 C1QA RAB31 PLK3 SKIL PTGER2 MALT1 ZCCHC9 TMEM128 MOB1A RUNX3 PKD2 CD86 CCR1 PITPNA TNFAIP8 ARPC2 ELOVL1 PIP4K2A RIPK2 SOAT1 ANKRD49 NFKBIA	down	***
CHICAS_RB1_TARGETS_GROWING	0.0000026	0.0000870	0.6272567	0.3877580	1.809994	215	FOXM1 HELLS KIF20A BUB1B NEK2 CCNB1 CENPF TIMELESS PSPH DDIT4 DEPDC1 PHGDH CDCA7 TTK GINS1 IQGAP3 GTSE1 KIF14 GMPS ASPM CDCA8 CENPA AKR1C1 TPX2 CCNB2 FIGNL1 RBBP8 UHRF1 MCM4 MCM2 CA12 SHMT2 HMMR SMARCC1 BUB1 TOP2A TPR MCM7 MCM3 RBP1 DNAJC9 RAD51AP1 OXTR RGS4 IDH2 CASP6 NCAPG2 NUSAP1 TMEM106C CBX5 POLE2 CENPH GMNN NAV2 PSAT1 COL3A1 EZH2 RNASEH2A NRGN SSRP1 GINS2 ANP32E ASNS CDC7 CENPK PTN SUPT16H NFXL1 CDC20 OLFML3 MCM6 LRRC15 LRRC17 STMN3 MARCKS MSH2 CCNA2 PRIM1 CDC42BPA	up	***
SMID_BREAST_CANCER_RELAPSE_IN_PLEURA_DN	0.0013047	0.0156287	0.4550599	0.6321047	1.809758	17	LTF CEACAM1 CP BAMBI SIX1 CXCL9 PSAT1 PEG10 CDH3 SRD5A1 S100A9	up	*
GO_POSITIVE_REGULATION_OF_STEROID_BIOSYNTHETIC_PROCESS	0.0048833	0.0419880	0.4070179	-0.6211774	-1.809506	13	IL1B WNT4 STARD4 ABCG1	down	*
GO_REGULATION_OF_SMOOTH_MUSCLE_CONTRACTION	0.0014975	0.0172264	0.4550599	-0.4269280	-1.809236	50	CAV1 CALCRL ADRA1D TBXA2R RHOA ATP2B1 ADA ADRB2 SETD3 CNN1 KCNMA1 NPNT TACR2 PTAFR SRF ADRA1A MYOCD RGS2 KIT EDN1 PRKG1 P2RX1 DOCK4 SPHK1	down	*
GO_MITOTIC_NUCLEAR_ENVELOPE_DISASSEMBLY	0.0036443	0.0338569	0.4317077	0.6951230	1.808954	12	CCNB1 PLK1 CCNB2 PRKCA CDK1 LPIN1	up	*
BIOCARTA_GCR_PATHWAY	0.0041617	0.0372589	0.4070179	-0.5739405	-1.808845	17	NR3C1 ANXA1 ADRB2 NFKB1 CALM2 PIK3R1 CALM1 HSP90AA1 PIK3CG	down	*
GO_REGULATION_OF_CENTROSOME_CYCLE	0.0015508	0.0176837	0.4550599	0.4774011	1.808831	52	PKHD1 SPICE1 MDM1 NEK2 BRCA1 STIL CCNF RANBP1 CEP250 AURKA POC1A KIF11 CHEK1 CENPJ TRIM37 CHMP4C CDK5RAP2 NUP62 CEP85 ALMS1 CHMP1A MARK4 CHMP2A	up	*
ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	0.0000000	0.0000003	0.7614608	-0.3173123	-1.808733	345	CXCL3 SEMA6A EREG HSPB7 ARHGAP31 IL1A DENND5A CD55 ZC3H12C IL1B RAPGEF2 MIR22HG CD44 CCRL2 NEDD4L FOSL1 UBE2FP1 IL23A ZEB2 PDE2A KCNAB1 TMPRSS6 ATP2B1 CLCF1 SGMS2 ADAM17 LIFR PRMT5-AS1 MTF1 BTG2 EIF5 RNF144B LITAF KLF6 PTX3 EIF4E TNS1 ZFYVE16 TCF7L2 GPM6A PPP3CC AGBL1 IL10 MAP2K3 STAT5A TBC1D9 ITPRIP PLAUR PXDC1 TNFSF15 DRAM1 NFKB1 CXCL2 IRAK2 CCL4 PNRC1 ZBTB43 DUSP1 MAFF RASGEF1B AFF3 SNN NINJ1 TCTE3 ZCWPW1 KANK1 FRY ID4 CD80 IL6 SERPINB8 CPEB4 MN1 HSPA1B PLK3 RCAN1 PPP1R15A WTAP ELOVL7 FERMT2 CD83 IRF8 SELENBP1 OSM REL TNFRSF9 TPRA1 ACSL1 NIPAL4 EHD1 DUSP5 ATXN1 GPR84 SOD2 ADORA2A-AS1 MACF1 MBNL1 SOD3 CCL20 ICAM1 ANKLE2 IL18 MIER1 ABL2 NBN XIRP1 RIPK2 TOB2 TDRP TRAF1 NFKBIA EDN1 TNFSF9 KIF1B LDLR SFPQ PURB DNAJB5 TRIM36 DMXL2 PIM3 SPSB1 CDON SERPINE1 SVIL CLEC4E HES4 ARL4D ATP1B1 YRDC HEY1	down	***
DOANE_BREAST_CANCER_ESR1_DN	0.0025753	0.0259282	0.4317077	0.5403701	1.808374	32	BBOX1 KRT5 GABRP UGT8 IGF2BP3 MPP6 KRT16 TTLL4 EGFR ASS1 SOX11 GJB3 PSAT1 CHST3 MMP7 PGBD5	up	*
GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN	0.0000097	0.0002708	0.5933255	0.3996997	1.808321	173	FOXM1 CEP72 SPATA24 CDC45 TICRR GMDS BUB1B NEK2 CCDC34 CENPF TG UBE2T MND1 TTK GINS1 IQGAP3 IFT122 TRAIP ESPL1 MYBL2 MIS18A CISD1 SAE1 MRPL27 WDR66 TOPBP1 PIH1D1 HES6 BRIP1 RAD18 FADS2 CNPY2 PPIL1 EFCAB11 CDKN2C SLC25A13 SSX2IP DYNLL2 SAPCD2 MTBP RECQL4 PA2G4 SPEF1 DPP3 TUBG1 DHX40 MBD4 SUDS3 CHTF18 GINS2 PKP4 KIF20B LRWD1	up	***
GO_PYRIMIDINE_CONTAINING_COMPOUND_BIOSYNTHETIC_PROCESS	0.0016452	0.0184571	0.4550599	0.4955266	1.808211	44	CPS1 GPAT2 TYMS UMPS TAMM41 NME1 NME9 NME5 CAD UCK2 UCKL1 UPP2 MTOR DHODH TK1 DTYMK AGPAT5 LCLAT1	up	*
ATGTTAA_MIR302C	0.0000019	0.0000671	0.6272567	-0.3349775	-1.808179	201	EDNRB CPEB2 PTP4A2 PTPRE ST6GALNAC3 BMP2 TTC7B FAM49A NUMB ZBTB4 UBR3 KIAA0355 NFIX B3GNT5 HBEGF LIFR FZD4 FOXP1 DACH1 SRSF2 PDE4D RAB14 ATP6V1B2 ATP10A ZMIZ1 MTMR6 SRSF5 ZCCHC24 MYO1B GAPVD1 FBXL3 UBQLN1 C1QTNF7 ELMSAN1 ARL4A TLL1 RBM39 METAP1 CREM PHACTR2 SF3B1 PPA2 GABPA OSM CGGBP1 EPC2 UBB SPOP AZIN1 NUP153 HNRNPA2B1 STRN SBF2 ATP6V1A IRS2 PPP3R1 TOB1 ANKRD12 KANSL2 MBNL1 RNF138 NRP2 NR3C2 ZFPM2 EIF4A2 SMAD4 RNF13 EHD3 SLC35A1 HNRNPH1	down	***
MODULE_98	0.0000000	0.0000011	0.7337620	0.3737885	1.807624	350	CCNO TRIP13 FOXM1 CDC45 TFAP2A NUP107 NEK2 COIL CCNB1 CENPF CPSF6 NPAS1 NDC80 NOVA1 PRIM2 SPDEF POLE PLK1 YEATS4 CENPA PTTG1 ESPL1 SOX9 E2F3 CCNB2 RBBP8 ZNF117 MYBL2 ORC1 NCAPD2 ZWINT NME1 MAP7 SMARCC1 KIF23 CHAF1A HLTF KNTC1 BUB1 TOP2A POLD2 TPR KIF2C MSX1 PRKDC SETDB1 RAD54L ZNF146 MCM3 CHAF1B LMNB1 CDC25C SOX4 EMG1 LIG1 TOPBP1 CHEK1 ACTL6A MAD2L1 NFYA FBL BLM TULP3 CDKN2C CBX5 CDK1 POLE2 GTF2E1 E2F1 UNG PRRX2 PSMB5 FEN1 EZH2 TAF6 SNRPE CBX1 PSMC4 VPS72 RECQL4 KPNB1 DNMT1 FANCG ILF2 CCNE1 PSMA5 ZNF133 SNRPA MBD4 KIF22 RAD51D ARF5 SSRP1 ADAR NFATC4 HDAC1 SAP30 KRT19 NRF1 POLD1 PSMD2 CDC7 PPP1R8 AP3M2 POP7 RPA1 POLR2J MCM6 STAMBP SRPK2 SNRPD1 DDX23 NEK4 SRSF1 KATNB1 RCC1 PMS1 BCL9 MSH2 CCNA2 PRIM1 ZNF195 STK38 GTF3C2 RFC5	up	***
GSE3982_MAC_VS_TH2_DN	0.0000057	0.0001725	0.6105269	0.4000094	1.807422	172	RUVBL1 C17orf75 GPR35 ANKZF1 SAP30L-AS1 UMPS PRC1 ORC1 GINS4 NCAPD2 COQ3 HMMR DLG1 NLE1 KIF23 DPY19L2P2 STAP2 KIF15 NUP155 TFR2 MRPL3 MCM3 CDC25C CC2D1A DCTPP1 MEOX1 ERCC2 CKS1B DDX51 ASF1B DIDO1 BIRC5 GOLGA8A ALDOB ZNF692 DHX34 DAP3 GALNT3 NRF1 RMND5B RDH16 TSTA3 DGKA CDR2 KIF21B MED24 TDP1 EXOSC5 POLR2I ATAD2 KRTAP5-9 DPH5 PMS2P1 CCNA2 SNRPD2 CAPN10 PPP6R2 RHOT2 HOXB2 PNKP SRCAP DDX52 SYNE2 CLASP1 CFI ZDHHC13 NSUN5 BAG2 FAF2	up	***
GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME	0.0018654	0.0202707	0.4550599	0.6037360	1.807028	21	NABP2 CCT6A CCT2 RUVBL2 CCT5 ATR PIH1D1 CCT3 LRWD1 CCT7	up	*
GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_CELL_CYCLE_CHECKPOINT	0.0009773	0.0124961	0.4550599	0.4515211	1.805315	67	CHEK2 CCNB1 BRCA1 E2F8 GTSE1 PLK1 TFDP2 DTL CASP2 AURKA PRKDC CDC25C SOX4 CHEK1 SOX11 MDM2 PML CNOT3 CDK1 E2F1 CNOT11 CNOT2 FZR1	up	*
GO_INTRACILIARY_TRANSPORT_INVOLVED_IN_CILIUM_ASSEMBLY	0.0028592	0.0280520	0.4317077	0.5225452	1.805230	35	IFT122 TTC26 IFT27 KIF3B IFT43 WDR60 IFT172 KIF3C SSX2IP DYNLL2 IFT52 TRAF3IP1 WDR34 WDR35 DYNC2H1 CLUAP1 TTC30B	up	*
LIN_MELANOMA_COPY_NUMBER_DN	0.0040915	0.0367851	0.4070179	-0.4509057	-1.804338	38	MED4 KLF6 CLN5 MTMR6 KPNA3 MARK3 ESD BAG5 MBP RPL21 TPT1 PTEN LPAR6 PAPSS2 SAP18 FNDC3A SUCLA2 EIF3J CDKN2A PROSER1 B2M	down	*
GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP	0.0000108	0.0002969	0.5933255	-0.3399034	-1.804150	180	LYL1 LY86 LDB2 MYADM FUT1 ADCYAP1R1 DYRK1A MKNK1 NCF2 ANAPC15 CD22 GGA2 SLC44A2 SH2B3 UBL3 TM2D3 IFI30 MS4A1 NDEL1 SPI1 MCL1 RAB14 CCL22 SELL EPS15 PER1 WFS1 HLA-DQA1 HCK PKIG ASNSD1 PHTF2 CTSS LIMD1 KCTD12 PLK3 SNX2 IRF8 RALB PLCG2 SNX9 RHOQ HIVEP2 CD74 IRF5 TCF4 TEC CBFA2T3 NFYC CD81 WBP2 KANSL2 SERINC3 PITPNA BMP2K CCR6 ZNF143 SPIB CD19 IQGAP1 EIF4A2 EIF4G2 CTSH CFL2 CNR2	down	***
GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN	0.0000131	0.0003513	0.5933255	0.3961278	1.804127	180	AK4 BDH1 BUB1B CCNB1 CENPF TTF2 SORD PHGDH NIPSNAP1 PLK1 CDC6 TPX2 CCNB2 TYMS MYBL2 CCT6A SHMT2 MYL6B NME1 RUVBL2 NDUFB8 HMMR CHAF1A PCCB CCT5 AURKA WDHD1 KIF11 MCM3 CDC25C CHEK1 AHCY IDH2 PARP1 TMEM106C HDGF NPM3 UNG PSMB5 FEN1 EZH2 SPAG5 FADD SRD5A1 CCNE1 TUBG1 GNPAT DLGAP5 SPTSSA CDC7 CKAP5 STAMBP MRPL28 HAX1 SLC1A5 NEFH FARSA AP2S1 PYCR1 PRIM1 GBP1 ATOX1 TMED9 ETHE1 VDAC3 CENPE MTHFD1 TP53 PAICS UBE2C BCAT2 ENO1 CYB5B SRM TOMM40 NHP2 PMVK CRYZ CCDC6 HNRNPAB MTHFD2 COX6A1 GRHPR EBNA1BP2 LAG3 CTPS1 PSMD8 ACOT7 ACTN4 COL6A3 SLC29A1 RFC3	up	***
GO_MITOCHONDRIAL_LARGE_RIBOSOMAL_SUBUNIT	0.0016550	0.0185343	0.4550599	0.4761465	1.804077	52	MRPL46 MRPL15 MRPL3 MRPL27 MRPS30 MRPL36 MRPL37 MRPL17 MRPL11 MRPL52 MRPL4 C12orf65 MRPL24 MRPL28 MRPL41 MALSU1 MRPL53 MRPL51 MRPL14 MRPL55 MRPL9 MRPL21 MRPL20 MRPL48 MRPL12 MRPL43 MRPL2 MRPL35 MRPL13 MRPL33 MRPL19 MRPL38 NSUN3 MRPL10 MRPL23	up	*
MODULE_189	0.0036244	0.0337591	0.4317077	0.7332818	1.803982	10	CENPA CHAF1A SETDB1 CHAF1B EZH2 CBX1	up	*
GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP	0.0000059	0.0001787	0.6105269	0.3991749	1.803651	172	GMDS CHEK2 CENPF FBXO27 MPP6 THOC3 CDK4 GTSE1 SNF8 STIL EIF2B5 PLK1 NUF2 PTTG1 GPI ESPL1 TPX2 UHRF1 WDR90 MKI67 TOP2A EME1 SAE1 RAB19 DPCD RRM2 RAD54L KIF11 PASK CHAF1B ZNHIT1 CHEK1 ABCB9 PRMT6 BLM PPP5C ALDOA PTPN3 CDKN2C ASF1B EXOSC2 RFWD3 CENPH NCAPG ETFB DGCR6 DNMT1 MZT2B CCNE1 DPP3 KIF22 MRPL11 CHTF18 LRWD1	up	***
GO_BICARBONATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY	0.0014883	0.0171394	0.4550599	0.6298720	1.803365	17	SLC26A4 SLC26A8 SLC4A4 SLC4A8 SLC4A11 SLC26A2 SLC4A9 SLC26A1	up	*
GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS	0.0012056	0.0147041	0.4550599	0.4607658	1.803286	60	AK4 GMPS TYMS UMPS AK8 DNPH1 DLG1 CARD11 CAD LRGUK UCK2 ATIC AK7 UCKL1 UPP2 DHODH TK1 DTYMK NT5M RAD50 PFAS ENTPD8 LHPP PNKP GMPR2 PAICS TK2 DGUOK ADSL APRT AK9 SHMT1 CMPK2	up	*
MODULE_46	0.0000000	0.0000018	0.7195128	-0.3195695	-1.803263	303	EREG IL1A FCN1 CD101 CD55 IL1B MNDA EMP2 GPR65 INSIG1 FYN LY86 FCER1A AQP9 CHIT1 ADRA1D C5AR1 NCF2 CD1C GAS6 CD22 IGSF6 LILRB3 CD8A FGR ERG DNAJC3 CD5 HBEGF ADA ENTPD1 KLF6 MS4A1 GATA3 IL18R1 GRN ZEB1 MTHFR PDGFA STAT5A BST1 TNFSF12 PTAFR DAB2 CCL3 CXCL2 SELL SELP CCL4 SFTPD CD53 PRF1 FCER1G CD300C EVI2A IL7R C4BPB IL24 ARHGDIB BTG1 EMP3 CD8B AREG IL6 CTSS IL2RB OASL CD48 C1QA ETS1 TYROBP IFNGR1 PTGER4 CD83 IRF8 GPR183 OSM CXCL5 CST7 RUNX3 KLRC2 CR1 CD6 CD86 PDCD1 CD81 ORM2 CCR1 FCGRT CLEC2B CCL20 GEM GPX3 IL18 LAT CXCR4 CCR9 CD19 BCAT1 NFKBIA ADORA2A CTSC EDN1 CD3G KLRK1 AIM2 CREG1 IL16	down	***
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN	0.0000062	0.0001861	0.6105269	-0.3392996	-1.802329	179	CXCL3 EREG IL1A HMOX1 ZCCHC2 CCNL1 DNASE1L3 HSPE1 CLCF1 PTS ADA PICALM ANPEP RNASE1 ZFYVE16 UBE2D3 PTPN12 MAP2K3 HNRNPA3 PLAUR SNIP1 CDS2 ZBTB43 CD53 DNTTIP2 MARK3 NCOA1 MMP19 TDRD7 NINJ1 PSEN1 CD48 DUOX1 OSTM1 PPP1R15A PTGER4 PSTPIP2 GRB2 ATP13A3 OGFRL1 CLN3 ACSL1 CALM1 YTHDF3 FOXO3 ICAM2 ITGA9 PHF11 MFSD12 IL18RAP ABL2 CEBPD LRP12 RIPK2 NLRP3 SP100 G3BP2 DOCK4 SFPQ WDFY3 DNAJB5 SPHK1 SPSB1 C1QB	down	***
VILIMAS_NOTCH1_TARGETS_UP	0.0014041	0.0164430	0.4550599	-0.4285975	-1.801649	47	PTCRA EGR2 BCL2A1 GATA3 NRARP BIRC2 ID2 CD80 JUNB CCR7 CD83 CD7 CD74 CD86 ICAM1 LAT TRAF1 NFKBIA CD3G EGR1 HEY1 CD69 TRAT1 GZMB IL10RA GZMA CD3D NFATC1	down	*
GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP	0.0000035	0.0001133	0.6272567	-0.3387720	-1.801423	176	FCN1 CD101 OLR1 LTA4H LPXN PTP4A2 MIR22HG CLDND1 PID1 BACH1 ST3GAL6 AQP9 CYB5R3 RBM14 HMGCR CD5 MTF1 ANXA5 REV3L SLC7A11 SRSF2 IL18R1 SLC25A37 PDE4D CD58 HNRNPA3 CASP1 THBS1 ARAP3 CD53 BTG1 FRY PGD PSMA1 DDX17 MAP4K4 TREM1 RHOG IFNGR1 CCR7 GLIPR1 IDS CDK2AP2 CST7 GRIK1 MOB1A SLC3A2 FOS HNRNPA2B1 TPMT KYNU PITPNA JUND ITGAE HNRNPK TRAF1 ENY2 DNAJB5 ZBTB44 PPP1CB C5AR2 DUSP6 TMEM43 PRKCH GPR153 FPR1 BBS7 A4GALT GNG11 FPR3 LAMP3	down	***
VALK_AML_CLUSTER_5	0.0034651	0.0326898	0.4317077	-0.4971851	-1.800982	26	SIRPB1 SLC15A3 EPB41L3 PILRA LILRB3 PTAFR TFEB CD86 CCR1 UBE2D1	down	*
MIR1233_3P	0.0009093	0.0117788	0.4772708	0.4478516	1.800845	69	KCNMB2 PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA7 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 CCL28 PCDHGA2 FAH PDRG1 TRIM32 PCDHGB1	up	*
GO_MITOTIC_METAPHASE_PLATE_CONGRESSION	0.0009338	0.0120428	0.4772708	0.4991257	1.800466	42	CCNB1 NDC80 KIF14 NUF2 CDCA8 CDT1 SPDL1 BOD1 KIF2C MAD1L1 CDCA5 PSRC1 KPNB1 CDC23 KIF22 CHMP4C NUP62 CHMP1A CHMP2A CENPE RRS1 CHMP6	up	*
GSE11386_NAIVE_VS_MEMORY_BCELL_UP	0.0000225	0.0005534	0.5756103	0.3990915	1.799991	168	TRIP13 MDM1 CDC45 BUB1B CCDC34 CENPF UBE2T PBK PGM2L1 NDC80 CDCA2 ASPM CDCA8 FIGNL1 PRC1 DTL MCM8 LILRB4 GINS4 SPDL1 MELK NDUFB8 KIF23 CEP55 KIF15 KNTC1 BUB1 AUNIP TOP2A MCM7 DPCD RRM2 RAD54L CDC25C RAD51AP1 PIH1D1 CDK1 GBP3 POLR3K NCAPG RAB11FIP4 CENPP EFTUD2 EDEM3 GALK2 GSS TUBB2A KIF22 HID1 KIF20B PSMD2	up	***
GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN	0.0000143	0.0003787	0.5933255	0.3951871	1.799843	180	TRIP13 CDC45 MCM10 NUP107 GGCT CDK4 ALDH18A1 ESPL1 CDC6 MCM4 MCM2 CDC25A PRC1 CCT6A SHMT2 XPOT CDT1 CCT2 NME1 RANBP1 HMMR EXO1 EEF1E1 AUNIP WDR3 POLD2 MCM7 MRPL3 PKM CHEK1 DNAJC9 DCTPP1 BLM CKS1B EXOSC2 UCK2 GMNN SMG9 PSMB5 MRPL17 FEN1 PA2G4 POLR2H TUBG1 SCLY LMNB2 TUBA3D MLEC GINS2 ASNS CCT7 CDC20 STOML2 BCL2L1 NOL6 MCM6 GINS3 SLC1A5 SHCBP1 ABCF2 MTHFD1 TP53 PAICS CISH ENO1 TUBA1C SMARCB1 RRS1 NUP93 KLHL2	up	***
GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN	0.0000147	0.0003881	0.5933255	-0.3462077	-1.799437	155	TMEM170B CD44 HMCN2 TMOD3 CALCRL CDC42EP2 SLC15A3 NR3C1 SCARF1 CCNL1 ANXA1 TNIP3 MAP3K8 COX18 FOXP1 KLF6 CLN5 MTHFR CSRNP1 CASP1 LIMS1 PTAFR PLAUR VASP KLF7 FBXL3 NFKB1 IRAK2 SELL PNRC1 PIK3R5 KREMEN1 TDRD7 USP25 MITF CCDC50 PI4K2B PCGF5 RC3H1 SYPL2 KCNA3 KAT2B RNF2 XKR8 ALDH1B1 EDN1 TLK2 TNFSF9 AIM2 MIER3 IRF2	down	***
GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN	0.0000143	0.0003787	0.5933255	0.3949431	1.798732	180	CDC45 MCM10 UBE2T TTK CDK4 ASPM EIF2B5 ECT2 CDC6 SFXN1 PRC1 CCNF EIF3B DTL RUVBL2 POLD2 MCM7 RRM2 PKM MRPL27 KIF11 ZNHIT1 TOPBP1 MAD2L1 AHCY ALDOA UQCR11 SSBP1 PSAT1 EZH2 DYNLL2 MRPS12 UQCC2 DDT EIF6 UBFD1 DPP3 GNPAT COA3 UBAC1 PSMA5 LONP1 KIF22 MRPL11 DTYMK POLD1 MARCKSL1 TIMM13 CPSF4 STOML2 LRRC59 MRPS33 MRPL51 NUP62 FARSA BANF1 MRPS25 PDAP1 PRPF31 SEC13 OXCT1 NDUFA8 ACP1 SMC2 GPN1 NDUFB7 NUP93 COX17 NCAPH DRG1 MRPL12 EIF2B1 CLPP TNPO3 EXOSC10 TMPO CDC34 TRIM59 ARL1 MTHFD2 PFKL COPS7A STMN1 ITPA EXOSC7 MRPL35 MRPL13	up	***
PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP	0.0013088	0.0156640	0.4550599	0.4595959	1.798707	60	ABCC2 KIF20A HJURP CIB2 CDCA8 CENPA AKR1C1 TPX2 PRKCA TYMS CCT2 MCM3 SKP2 CKLF OSMR SUN1 KPNB1 UBFD1 SAP30 LRRC59 ASCC1 BCL2L1	up	*
MIR3688_3P	0.0000000	0.0000004	0.7614608	-0.3160464	-1.798210	341	RTKN2 ZNF366 OTUD7A FOXF1 GPR15 ZC3H12C ATXN3 ADCY9 KCTD9 OTUD1 MMRN1 PLEKHF2 CCDC88A LDB2 NEDD4L CDH13 BMPR2 YPEL5 ACER3 HSPE1 CYP17A1 B3GNT5 SLC2A14 LTBP4 UBL3 TACC1 C1orf21 RANBP9 SPIRE1 ZBTB21 FOXP1 GLS STOM PLXNA4 CD93 HNRNPU TMEM38B ROCK2 CSRNP1 MOAP1 PEG3 FAM76A LEPROTL1 USP2 STK17B RIT1 EPGN CXXC4 SHE MPC1 GNAQ PRICKLE2 TM9SF2 SMNDC1 CNOT6L RASGEF1B PIAS1 SRGAP2C SLC8A1 CD80 MAGI2 SRSF3 SH3BP5 GABPA DESI2 SHOC2 APBB2 VPS26A SKIL GLIPR1 CREB1 KBTBD8 ATP13A3 HOMER1 NAA30 EPC2 FOS PSMD12 ZFAND6 VAV3 AP1G1 ITGA9 TGIF1 VAMP4 RSBN1L MIA3 NFYC ATXN1 SBSPON CSNK2A2 SERINC3 FAM98B INO80D CCL20 RNF2 MIER1 LMOD1 BLOC1S2 LRP12 HNRNPK G3BP2 SRSF10 MARC1 JMJD1C PAK2 CECR2 RORA DCUN1D2 SCLT1 MAP4 ABI1 UBE2V1 PLAG1 UBR2 CFL2 DKK3 CAPZB LHFPL2 MYH10 DYNC1I2 FAR1 COX20 PPIP5K2 DPF3 API5 UBE3A SGPP1 PCDH15 ATP2B4 SLC23A2 WDR26 RAB1A UEVLD SIRT1	down	***
GO_RECEPTOR_INTERNALIZATION	0.0004023	0.0061948	0.4984931	-0.3801302	-1.798149	84	RAMP3 SFRP4 RAMP2 PCSK9 CAV1 CALCRL CD9 NUMB CD36 PICALM WNT3A TFRC ARRB1 SDCBP ARC FCER1G EPS15 TBC1D5 LRRTM2 MAGI2 RAB31 ACKR3 GRB2 SNX1 GRIA1 PLCG2 MTMR2 CD81 ANKRD13A GRK4 ARRB2 RAB5A	down	**
MODULE_53	0.0000001	0.0000055	0.7049757	0.3745087	1.798090	323	RIBC2 TRIP13 DDX11 ENTPD2 FOXM1 BIK CDC45 TROAP BUB1B CCNB1 CENPF IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 NDC80 ECE2 GINS1 GTSE1 KIF14 GMPS PLK1 CENPA PROC PTTG1 TPX2 CCNB2 MCM4 MCM2 TYMS MYBL2 CCNF SRPK1 SHMT2 NCAPD2 ZWINT CASP2 HMMR NUDT1 KCNN4 CHAF1A MKI67 PRB4 KNTC1 PAFAH1B3 EEF1E1 TOP2A CARD10 POLD2 KIF2C MPO RRM2 PRKDC SLC22A18AS RAD54L KIF11 MCM3 LMNB1 SOX4 SALL2 MDK CD24 TOPBP1 MAD2L1 SCAMP5 MSI1 ABCB9 PKMYT1 BLM FADS2 CLDN9 RECQL5 CDKN2C TMEM106C CDK1 EXOSC2 NPM3 E2F1 UNG PEG10 FEN1 EZH2 NUP205 ARTN TTI1 CBX1 RECQL4 RNASEH2A TBX1 DNMT1 LGR5 DLGAP5 LMNB2 DPH2 DTYMK DBN1 FZR1 PCDH9 IGHM ASNS OLFML2B MAT1A CDC7 DNASE1 CHPF KLHDC3 CKAP5 CDC20 RRP9 RPA1 WNT10B MCM6 KIF21B	up	***
WACKER_HYPOXIA_TARGETS_OF_VHL	0.0026345	0.0263085	0.4317077	0.7163292	1.797935	11	CA9 CP PFKP PDK1 P4HA1 ADM HK2	up	*
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_DN	0.0000172	0.0004447	0.5756103	0.4016625	1.797571	155	GRIP1 MMP13 SLC29A4 EYA1 LIPM AK4 PAX9 CCDC34 POLQ TRIM17 THEM5 FABP6 C4orf19 PRKCA RAD54B TNNT2 KCNH2 CLHC1 MYBPC2 THBS4 HAVCR1 SYT2 RIPK4 NEB EHF PSRC1 MYOT MB EPHA1 CENPH ATP2A1 NAV2 TNNI2 TRIM7 SMO FOCAD HSPA4L GDPD3 MC1R CCDC151 PCDH9 SMTNL1 CEP128 NR6A1 TEX21P RSPH10B RPGRIP1 UPK1B CKMT2 CABP7 ANKRA2 DPY19L2 STAC3 RSPH4A FARSA SCRG1 ELFN2	up	***
GSE19512_NAUTRAL_VS_INDUCED_TREG_DN	0.0000126	0.0003417	0.5933255	-0.3458904	-1.797501	153	SIRPB1 RBP4 EPAS1 EREG NOVA2 ABHD5 OLR1 DENND5A FCN3 LPXN PTPRE INSIG1 PPP4R1 NR3C1 CD5 PBX3 SERPINB9 CRTAM CD58 KIAA0513 CASP1 GCHFR CCL3 NPAS3 CXCL2 CCL4 UBE2B ELK3 RAP1GDS1 GNAQ HEXB RBPJ FLT1 LRRTM2 PSEN1 IL2RB KCTD12 BMP3 GSTO1 PABPC4 REL CD7 TNFRSF10B SLC25A24 NAPG	down	***
GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_DN	0.0000142	0.0003782	0.5933255	0.3984239	1.796948	169	TICRR CHEK2 TIMELESS KIF18B BRCA1 TMC1 ASPM EBF3 TPX2 CCNB2 PRKCA CCNF RCCD1 NLE1 CHAF1A MKI67 KNTC1 POLD2 IGLV1-44 CDCA5 NT5C1B RPS2P45 SLC25A39 TIMM50 SPC24 DSCC1 BLM PSRC1 MRPL37 SERTAD4 C1orf112 E2F1 UNG SSX2IP EZH2 SPAG5 EFTUD2 C3orf67 POLR2H SNRNP25 MYO19 DNMT1 TUBG1 PUS1 RAD9A TJAP1 KIF20B ANAPC1 NUP85 PFAS CDC20 POP7 MGME1 MCM5 ACOT11 DDX23 SNAP47 SRSF1 SLC1A5 TCHP UNC119B GLO1 PRR11 CISD3 TXNL4B TARBP1 WDR76 TARBP2 CGN ALG1 PRPF3 SART3 KIAA0586 ZNF511 MRTO4 RNF126 ZC3HC1 TOMM40 SNHG17 TLE2 DUS3L GLRX5 URB2 TRIM59 RMI1 TBC1D2B CTPS1 TLE1 SKA2 MMP12 SLC39A3 SLC29A1 NRP1 TXNRD3 NVL GSR	up	***
ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP	0.0045789	0.0400564	0.4070179	-0.4897922	-1.796530	28	CAT FUCA1 RB1 ATP6V1B2 CST3 KIAA0513 PRCP TIMP2 APLP2 FCGRT TIAM1 CXCR4 S100A4	down	*
GSE7852_LN_VS_THYMUS_TCONV_DN	0.0000125	0.0003390	0.5933255	0.3951656	1.796518	179	PARPBP MCM10 CCDC34 IGF2BP3 TIMELESS PBK DEPDC1 TTK E2F8 PLK1 CENPA ECT2 ESPL1 CDC6 NNT FIGNL1 UHRF1 STRIP2 PRC1 CCNF MELK TOP2A SFI1 KIF2C MCM7 E2F2 CDCA5 RAD54L SOX4 PFKP RAD51AP1 DSCC1 PTGFRN BLM SKP2 CKS1B NCAPG2 NUSAP1 ASF1B CDK1 ABHD17C AAGAB EZH2 RALGPS1 CBX1 CENPP ALDH7A1 TRIM37 ITFG2 GK5 ATAD5 ATP13A1 SASS6 SUPT16H CDC20 RPL7L1 CENPT RAB3D SUOX MARCKS ZNF212 PRIM1 PRR11 DBNL CAP2 RAD51 PTPRF CENPE FRMD6 UBE2C C4orf46 NCAPH TTC5 RNF14 CEP290	up	***
GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP	0.0000063	0.0001872	0.6105269	-0.3384342	-1.796518	178	SIDT2 ST8SIA6 KLF13 SPNS1 LIPA IL1RL1 ZBTB2 PDE2A CHMP1B BTG2 FOXP1 PPP3CA TMEM123 BTG3 ADAMTSL4 ZYG11B CCNI PPM1K STK17B SELL PNRC1 CCND2 CD53 PIK3C2A SMAD7 MBD2 UBASH3B DEGS1 AFF3 NRROS CD8B CREBRF S1PR4 ELF1 UTRN ETV3 JUN LIMD1 NXPE3 UBAC2 GMFG OSM IDNK TNFRSF9 RNF146 PLCG2 PELI1 CD164 TGIF1 PDLIM1 MFNG EIF3F IL18RAP LAT TAB2 SSH2 S100A4 PTEN LPAR6 GIMAP4 EHD3 EGR1 CDKN1B FAM8A1 KBTBD11 SNX14 KIDINS220 STX16 RNF111 TRIM25 SLC25A45 MAT2B AKAP13 KLRC1 ANKH FBXO33 CRLF3	down	***
GO_MEMBRANE_REGION	0.0000000	0.0000018	0.7195128	-0.3254154	-1.796480	275	SLC6A4 TNR AKAP5 HMOX1 TEK OLR1 DLC1 EDNRB PECAM1 ADTRP CD55 EMP2 FYN CAV1 CORO1C MYADM CDH13 BMPR2 ADCYAP1R1 S1PR1 PRKAR1A MAL CBL TGFBR2 RFTN1 SCN5A CD8A CD36 ATP2B1 ADAM17 ABCG2 MALL CAV2 PAG1 MS4A1 STOM LAMTOR3 CRK SGCA LRP4 PPT1 AHNAK KCNMA1 BIRC2 SDCBP SORBS1 CTSD PTPRC HPSE ARC UNC5A PTGIS GNAI2 BACE1 ADD1 PI4K2A HCK KCNA5 MYO1C PPP2CA ADCY2 PSEN1 PIKFYVE CD48 ADRA1A	down	***
GO_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME	0.0008723	0.0114538	0.4772708	-0.4049443	-1.796427	61	SRSF7 DYRK1A RBM7 TRA2B RBM4 SRSF2 HNRNPU SRSF5 REST SRSF3 CELF1 DDX17 WTAP SMU1 DDX5 MBNL2 CELF2 SRSF6 SRSF4 KHDRBS1 MAGOH MBNL1 SRSF10 THRAP3 SFPQ SAP18	down	*
GO_PYRIMIDINE_RIBONUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS	0.0023892	0.0245661	0.4317077	0.7584996	1.796160	9	UMPS CAD UCK2 UCKL1 UPP2 DHODH	up	*
GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP	0.0000064	0.0001893	0.6105269	-0.3383191	-1.795907	178	SLPI DENND5A GPR65 RAPGEF2 PTPRE LRRFIP1 FOSL1 ZCCHC2 CDC42EP2 SLC15A3 AGTPBP1 RRAGC ANPEP KLF6 ADIPOR1 SIRPA TCF7L2 CD37 ATP6V1B2 CFD TLE4 YBX3 STK17B MAP1LC3B CEBPA DENND3 MAFG KLF7 LY96 COTL1 HPSE EVI2A B9D2 PPP2R5A SLC6A6 NRBF2 ANXA3 NCOA1 SRF PRCP PGD RNF141 SEC14L1 CYB5R1 HK3 RHOG IFNGR1 PALM PSTPIP2 RPS6KA1 TNFSF13 NOP10 BAZ2B APLP2 NQO2 ZNF267 CCNH BMP2K ICAM1 XKR8 DHRS12 CUL3 PTEN DAZAP2 IRF2 ZNF106 CLEC4E FTL SH3GLB1 ZYX HAS2	down	***
GO_SMOOTH_MUSCLE_CONTRACTION	0.0004484	0.0067419	0.4984931	-0.3782005	-1.795873	87	EDNRB CAV1 CALCRL ADRA1D TBXA2R RHOA ATP2B1 ADA NMUR1 ADRB2 PDE4D SETD3 CNN1 ROCK2 KCNMA1 NPNT TACR2 PTAFR ROCK1 PTGER3 PIK3C2A RAP1GDS1 MYH11 SRF SLC8A1	down	**
MIR1284	0.0000020	0.0000708	0.6272567	-0.3362317	-1.795732	191	CD55 CPEB2 ST6GALNAC3 BDNF STXBP6 WBP4 ZBTB2 CD8A EIF4A1 UBL3 NLK REV3L KLF6 CAMTA1 ZNF697 ADRB2 EPB41L2 SNAI1 SORBS1 PPM1K ACSL3 REST UBQLN1 ID2 CAPZA2 PIK3C2A WDR48 PPP2R5C PDE1C MARK3 FAM76B PIAS1 ID4 KIF13A HCFC2 SF3B1 MCM9 FYTTD1 SKIL PCGF5 DENND4A SPRY4 KAT8 TSHZ3 DAGLA NUP153 PDS5B PDLIM1 ATXN1 INO80D HACE1 RNF2 LDLRAD4 FKBP1A CTTNBP2NL TAB2 UBE2D1 SP100 CREBBP SRSF10 RORA LDLR ZFPM2 KALRN PEX14 SVIL SLC19A2 OSGIN2 RB1CC1 KMT2E SGIP1 TSC22D2 HMGB1 RNF214 ARHGEF12 TES EP300	down	***
GO_CHROMOSOME_TELOMERIC_REGION	0.0000752	0.0015238	0.5384341	0.4140887	1.795614	122	CHEK2 THOC3 PIF1 NABP2 MCM4 MCM2 ORC1 TP53BP1 CBX3 ATR MCM7 PRKDC MCM3 CHEK1 XRCC1 BLM PML PARP1 TERC CBX5 CDK1 DNA2 FEN1 EZH2 CBX1 RECQL4 TEP1 TELO2 DCLRE1C RAD51D LRWD1 POLD1 SLX4 RAD50 RPA1 MCM6 THOC5 WRNIP1 MCM5 MSH2 RTEL1 RAD51 SIRT6 APEX1 NAT10 NHP2 RNF8 DCLRE1B DCLRE1A POT1 XRCC5 CTC1 ORC5 MEN1 XRCC6 ZBTB48	up	**
PID_PDGFRB_PATHWAY	0.0000389	0.0008777	0.5573322	-0.3566003	-1.795309	124	FYN BAIAP2 S1PR1 CBL FGR RHOA RAP1A PAG1 CRK STAT5A ACTR3 PIK3R5 ACTR2 HCK SRF PPP2CA WASF2 JUN RAPGEF1 PIK3R1 PRKCE GRB2 YWHAZ FOS MAPK8 MYOCD TAGLN JUND ARPC2 RAB5A ARPC5 PTEN DOCK4 GRB10 IQGAP1 SPHK1 ABI1 MAPK1 PIK3CG YWHAB SLC9A3R2	down	***
NAKAMURA_CANCER_MICROENVIRONMENT_DN	0.0010383	0.0130857	0.4550599	0.4976842	1.795266	42	TRIP13 FANCI PSPH CDCA2 CDC6 CCNB2 BUB1 AURKA KIF2C KNSTRN PSAT1 SPAG5 ARTN PA2G4 ASNS CDC20 LSM4 RFC5 USP39 TNS3 DHRS3	up	*
MODULE_154	0.0013820	0.0162885	0.4550599	0.4763098	1.794827	51	COL17A1 SAA1 TFPI2 TP63 KRT5 S100A2 TENM2 COL7A1 AKR1C1 GPX2 LAMC2 F2RL1 TRIM29 ITGB4 CDH3 HAS3 S100A9 FXYD3 LIPG CXCL1 PTHLH FBN2 FGFBP1 KRT17 BARX2 KLK10 PTPRK ROPN1L	up	*
HOLLERN_PAPILLARY_BREAST_TUMOR	0.0051849	0.0439766	0.4070179	0.6553191	1.794612	15	BBOX1 HP UGT8 RHOV CEL WNT5B KRT19	up	*
MODULE_127	0.0047109	0.0408360	0.4070179	0.6895428	1.794432	12	CENPA CHAF1A SETDB1 CHAF1B EZH2 CBX1	up	*
DODD_NASOPHARYNGEAL_CARCINOMA_DN	0.0000000	0.0000000	1.1330899	0.3492150	1.793630	1250	PRLR PCSK6 FAM83B TP63 DDX11 FOXM1 SLCO5A1 HELLS KIF20A HJURP CDC45 TICRR PARPBP MCM10 FANCI CHEK2 BUB1B NUP107 ZNF84 NEK2 CCNB1 CENPF TIMELESS POLQ FLVCR1 UBE2T PAIP1 CPSF6 COA1 PSPH GGCT MND1 PBK KIF18B COL27A1 TTF2 NDC80 PHF14 TSFM PRIM2 DEPDC1 BRCA1 PHGDH DEPDC1B CDCA7 C12orf66 ZNF138 METTL1 TTK GINS1 C6orf141 CDCA2 CDK4 RACGAP1 IQGAP3 KIF14 UBE2Z ANLN CCDC14 GMPS NIPSNAP1 AC011043.1 ASPM MMP1 FLAD1 NUF2 CENPA PTTG1 ECT2 CCL8 CDC6 SFXN1 TPX2 E2F3 GAPDH NNT CCNB2 FIGNL1 ANKRD22 RBBP8 FCGR3B UHRF1 KNOP1 MCM4 SPATS2 MCM2 RAD54B TYMS ZNF117 CDC25A UMPS PMS2 FERMT1 PRC1 COL22A1 CCNF EIF3B DTL CCT6A MCM8 KCNJ8 XPO5 MIS18A CAND1 SHMT2 RCCD1 XPOT ZWINT CCT2 SPDL1 AGK LSM5 NME1 RANBP1 CXCL10 C5orf34 TTLL4 KREMEN2 BZW2 CCDC150 MELK HMMR EXO1 NUDT1 C19orf48 KIF23 CEP55 CHAF1A MKI67 BOD1 KIF15 LINC00665 KNTC1 RHNO1 BUB1 CCDC77 EEF1E1 TOP2A CENPL HOMER3 DPY19L1 PUS7 AURKA EME1 ZNF112 NUP155 CBX3 WDR3 ATR VASH2 KIF2C MCM7 IFI44L RSRC1 MPHOSPH9 RRM2 GNAS-AS1 CDCA5 PRKDC RBM28 PDCD5 WDHD1 HOXC6 RAD54L MRPL3 ZNF146 KIF11 GPSM2 MCM3 CHAF1B LMNB1 CDC25C MCCC2 AIMP2 SOX4 YEATS2 BRI3BP PLXNA1 TMEM200C TOPBP1 CHEK1 ZNF618 DNAJC9 ORC6 MAD2L1 TRMT61B AHCY FBL CENPO RAD51AP1 DSCC1 BRIP1 CAD GNPDA1 RAD18 IPO9 CXCL9 PHB RGS4 ZNF587 TFCP2 CNPY2 SKP2 PSRC1 MARK1 CASP6 ZCRB1 CXCL11 KNSTRN CKS1B NCAPG2 NUSAP1 CBX5 URI1 ANAPC5 ZNF45 CDK1 CDK12 SSBP1 POLE2 CENPJ UCK2 CENPH BIRC5 ZNF260 CCT3 ATIC GMNN E2F1 UNG NCAPG VANGL2 TRAP1 DNA2 SLC25A13 DHX33 PSAT1 NEIL3 ANAPC7 FEN1 COL3A1 SSX2IP EZH2 NUP205 SPAG5 NF1 TTI1 NAPEPLD SNRPE NLN CBX1 UQCC2 NOP2 DIAPH3 ARNT2 DENND1A GBP5 LINC00173 PA2G4 RNASEH2A KPNB1 CHCHD3 POLR2H MYO19 FANCG UBFD1 INTS7 ILF2 CEP192 TRIM24 COL1A1 COL1A2 DLGAP5 ARHGAP11B ADAM12 CNOT2 ADNP DNAJA3 PUS1 C12orf45 SNRPA LMNB2 COL5A2 EPHB2 DUSP12 ZNF37A ZNF234 TK1 ADAR DTYMK C1orf131 CENPQ JMJD4 ESCO2 IL15RA GINS2 PDRG1 PKP4 KIF20B ASNS ANAPC1 FKBP14 SND1 C12orf73 NUP85 FAM200A MAGOHB CCZ1 SCNN1G ZNF140 SLC1A3 MARCKSL1 NT5M CDC7 YARS2 DHTKD1 CENPK SASS6 CKAP5 USP18 CPSF4 PSMB3 KLHL23 PALB2 C12orf65 FBXO22 AP3M2 MRPS23 FANCM MRPL24 MCM6 HOXA3 MGME1 ANKIB1 STAMBP RPL7L1 RAI14 PRMT1 CKAP2 XRCC4 HEATR1 SNRPD1 MALSU1 HAUS6 SNAP47 LTV1 SRSF1 C1orf109 GINS3 ZSCAN32 AATF EXOSC5 RTKN ETV6 CCNG1 TXNL4A VPS53 GAD1 ZNF780A DDX55 ATAD2 GOSR2 U2AF2 TSR1 CEP152 COPZ1 GTPBP10 NUP62 DPH5 CKAP4 ZNF286A INTS8 ADORA3 SUV39H2 ZNF519 PMS1 MSH2 TM7SF3 CCNA2 SMARCA4 PRIM1 ZNF195 PRR11 DENR RFC5 GBP1 NAV1 TUBGCP4 ABCF2 WDR4 RAD51 ZWILCH TRIP6 ST20 RASSF4 ARHGAP11A MRPL9 TARBP1 LLPH PAXIP1 ZNF121 CPOX UBAP2L LINC00839 ZNF131 SMC2 ZNF567 POLR1B CPT1C RNF213 CENPE TCF3 POLR1A DNAJC14 PFDN4 EARS2 DDX52 ROBO1 CBWD1 TRUB1 SEPHS1 PAICS PPIA EPHB4 UBE2C PNN NCAPD3 ANKRD46 FUT10 PWP1 OAS3 ENO1 RAD1 DNM1L ZNF367 C4orf46 CLASP1 CALU BRIX1 ARHGAP8 TIPRL ZNF562 CCL13 NCAPH ALKBH2	up	***
MODULE_178	0.0057535	0.0474211	0.4070179	-0.6157105	-1.793581	13	EPAS1 ANPEP TNFSF12 MMP19 FGF2 IL18 NRG1	down	*
GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_UP	0.0000302	0.0007090	0.5756103	0.3987710	1.793466	161	CA9 FAM153A CLGN DEPDC1 BRCA1 LCN2 COLQ TRAIP POLE CEP70 GPI TFDP2 ARHGAP33 SMARCC1 BUB1 TOP2A AURKA POLD2 PRKDC RAD54L MRPL3 MCM3 C11orf16 POLR3C DNAJC9 CC2D1A BRIP1 FNTB REPIN1 IDH2 MGLL HSPBP1 SKP2 TNFRSF21 ATP2A1 TRIM2 EZH2 STK11 MYO19 TUBG1 ALDH7A1 NINL MLF2 SNRPA TK1 KRI1 ZSWIM1 ZNF282 POLD1 ATAD5 PFAS CXCL1 THOC5 METTL2B LRRC17 NOC4L CLUH U2AF2 MICAL3 GLO1 ABCF2 CARHSP1 ZWILCH FAIM BCAT2 WIZ NCAPH ACSBG1 PRSS50 BAG2 PLK4 TBC1D10B HINT1 VAC14 GLRX5 DCLRE1B MSH6	up	***
GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP	0.0000113	0.0003088	0.5933255	-0.3409265	-1.793196	164	CXCL16 IL1B MIR22HG SIK1 EGR2 BACH1 TMEM138 GPCPD1 S1PR1 YPEL5 FRAT1 ANXA1 BTG2 EIF5 SRGN SORBS3 DGKE LEPROTL1 KLF11 TADA2B CYP20A1 ID2 SNORA28 RNF139 SH3BP5-AS1 SLC25A32 MYH11 PIK3R5 IKZF5 VCPKMT SLC25A33 CCNY AREG DNLZ IFNGR1 PTGER4 ATXN1L CD83 RC3H1 TPP2 TSPYL1 ADNP2 KLF2 SRSF6 FAM204A CDC37L1 IRS2 TBRG1 KANSL2 SF1 IQSEC1 TXNDC11 PSME4 EDN1 ZNF791 DNAJB9 CYTH1 DAZAP2 C1orf52 SFPQ ZNF326 TNFSF8 ZFP36 TRPM7 SPTY2D1 NOL9 ZNF14 DDX21	down	***
PID_CD8_TCR_DOWNSTREAM_PATHWAY	0.0023071	0.0238846	0.4317077	-0.4270379	-1.792783	48	FOSL1 NFATC3 CD8A PPP3CA PRF1 CD8B IL2RB JUN STAT4 JUNB PRKCE TNFRSF9 FOS MAPK8 IFNAR1 PPP3R1 CD3G EGR1 MAPK1 CD3E GZMB NRAS FASLG B2M CD3D NFATC1 IFNG	down	*
GO_PATHWAY_RESTRICTED_SMAD_PROTEIN_PHOSPHORYLATION	0.0017750	0.0195277	0.4550599	-0.4229638	-1.792437	50	SMAD6 ACVRL1 BMPER BMP2 ENG BMPR2 TGFBR3 TGFBR2 NODAL SDCBP DAB2 SMAD7 INHBA TGFB2	down	*
GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP	0.0000071	0.0002076	0.6105269	-0.3432408	-1.791772	158	CXCL3 KMO ASGR1 TRHDE RBMS2 DCSTAMP CLDND1 SIK1 RUNDC3B RCOR1 CAV1 BAIAP2 OTUD4 ATP2B1 SH2B3 FOXA2 ABCG2 BZW1 CSGALNACT2 GLS NDEL1 CRTAM BTG3 MCL1 PDGFA KRT4 MAP2K3 KLF4 SOCS2 PER2 ARC MATK SLC25A32 ADAMTS8 ZNF706 NINJ1 VPS37A UBQLN3 ADAMTSL2 NXF1 SERPINB8 AK1 PELI1 EHD2 BTBD7 MRPL39 TSC22D1 NAB1 GATA6 ACTN2	down	***
KEGG_GRAFT_VERSUS_HOST_DISEASE	0.0051039	0.0435348	0.4070179	-0.5683160	-1.791119	17	IL1A IL1B PRF1 KLRD1 HLA-DQA1 CD80 IL6 CD86 HLA-DRB1 GZMB KLRC1 FASLG IFNG	down	*
GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN	0.0000487	0.0010595	0.5573322	0.3990897	1.791088	158	SLCO5A1 SPICE1 EYA1 SPOCK1 CDC45 TROAP UCHL1 KIF18B PLK1 IGKV4-1 LAMP5 TPX2 CDC25A SPINK1 CDT1 TNC EXO1 SOX30 RAD54L OAZ3 SARS2 KDELR2 IGKV1-5 ASS1 SCAMP5 GAS8 EHHADH BLM TSHR ASF1B CDK1 EFCAB6 BIRC5 SPAG5 QPRT NRGN EFCAB2 KIF22 TK1 NOC2L COG4 ZNF814 MAT1A CHPF ASRGL1 SSH3 RABEPK LANCL2 HAX1 YIPF2 SUOX MYH3 NT5DC2 PYCR1 CEP85 HOXB2 CTTN TIMM44 UBE2C COPZ2 DHRS9 ZBP1 CALU	up	**
GO_EXTRACELLULAR_TRANSPORT	0.0029327	0.0286372	0.4317077	0.5710560	1.790270	25	STK36 SPAG17 KIF27 DPCD NME5 GAS8 DNAH11 CCDC40 KIAA0556 LRRC6 DNAH5 SPA17 DNAH1 ARRDC1 DNAAF1 ROPN1L	up	*
REACTOME_TELOMERE_C_STRAND_LAGGING_STRAND_SYNTHESIS	0.0036526	0.0338908	0.4317077	0.5781372	1.790211	24	PRIM2 POLA2 POLD2 LIG1 DSCC1 BLM DNA2 FEN1 CHTF18 POLD1 RPA1 CHTF8 PRIM1 RFC5 CTC1 POLD3 RFC3 RFC4 PCNA WRN	up	*
SEMBA_FHIT_TARGETS_DN	0.0045380	0.0397940	0.4070179	0.7275296	1.789831	10	CENPF ASPM ECT2 BIRC5 SPAG5 MNS1 DTYMK	up	*
GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0000064	0.0001893	0.6105269	-0.3366117	-1.789757	175	NLRC4 CXCL16 COQ2 CD44 MYD88 ELF2 STX11 FGR IER2 SH2B3 TACC1 RASGRP4 ANPEP SERPINB9 C1orf162 PPP3CA CD93 SPI1 MCL1 CST3 TLE4 ZSWIM6 RRM2B LINC00324 NFKB1 P2RY2 SELL HPSE KCTD20 ARAP3 TM6SF1 CD53 DUSP1 DSE CNOT6L FLT1 CTSS OASL UTRN DNAJA1 IPO7 FRYL RAB8A PLCG2 ADNP2 NOP10 USP7 TREX1 VAV3 SERPINB1 NAB1 IFNAR1	down	***
WHITFIELD_CELL_CYCLE_G1_S	0.0001362	0.0024933	0.5188481	0.4154698	1.789739	115	MNX1 MDM1 DDX12P CDCA7 FLAD1 CDC6 UHRF1 MCM4 MCM2 CDC25A ORC1 DTL MAP2K6 TRIM45 CASP2 CHAF1A E2F2 CLSPN PASK CHAF1B HORMAD1 TOPBP1 TRMT2A DSCC1 MBOAT1 SKP2 RNPC3 GMNN E2F1 UNG VPS72 RECQL4 FANCG CCNE1 GINS2 AP3M2 ABCA7 MCM6 MCM5 GINS3 AP4B1 ATAD2 INTS8 MSH2 ZMYND19 WDR76 ADCY6 PNN ADCK2 ZNF367	up	**
WAKASUGI_HAVE_ZNF143_BINDING_SITES	0.0027697	0.0273274	0.4317077	0.4766030	1.789737	49	CHEK2 BRCA1 POLE PMS2 EXO1 PRKDC FANCD2 CHEK1 RAD18 RECQL5 FEN1 RECQL4 FANCG RAD9A POLD1 POLB TDP1 MSH4 PMS1 MSH2 XPC TP53 APEX1 RAD1 MUS81	up	*
GO_INTERLEUKIN_2_PRODUCTION	0.0013291	0.0158622	0.4550599	-0.4101036	-1.789670	58	IL1A IL1B SLC11A1 ANXA1 CLEC7A GATA3 TRAF6 SPTBN1 PDE4D PTPRC SFTPD FCER1G CD80 CD83 MALT1 TBX21 CD34 CD86 PDE4B IL18 RIPK2 HAVCR2 KAT5 ZFP36 CD3E IRF4 CD4 PNP	down	*
GO_CILIARY_BASAL_BODY	0.0001483	0.0026729	0.5188481	0.4231568	1.789548	97	PKHD1 RPGRIP1L CENPF MKS1 FANK1 IFT122 TTC26 CEP250 BBS1 FBF1 POC1A AGBL4 IFT172 GAS8 CBY1 RABEP2 C2CD3 DLG5 CENPJ KIF7 SSX2IP POC1B LCA5 IFT52 BBS5 TUBG1 CCDC151 TRAF3IP1 AGBL2 WDR34 ODF2L WDR35 NEK4 FAM161A TBC1D30 TTLL6 B9D1 ICK MARK4	up	**
BIOCARTA_VOBESITY_PATHWAY	0.0048103	0.0415002	0.4070179	-0.8379666	-1.789029	5	PPARG LPL NR3C1	down	*
REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX	0.0010979	0.0136687	0.4550599	0.4534920	1.788774	62	CDC6 E2F3 MCM4 MCM2 ORC1 MCM8 CDT1 MCM7 E2F2 MCM3 ORC6 PSMD4 GMNN E2F1 PSMB5 PSMC4 PSMA5 PSME2 PSMD2 PSMB3 MCM6 MCM5 PSMB4	up	*
GO_SPECIFIC_GRANULE_MEMBRANE	0.0003507	0.0055705	0.4984931	-0.3840021	-1.788750	78	OLR1 HVCN1 RAB44 CLEC12A PTPRB CD36 SLC44A2 CD33 RAP1A STOM LAIR1 CD93 LAMTOR3 BST1 PLAUR ATP6V1D TMBIM1 CD53 DEGS1 CMTM6 HGSNAT SNAP23 ATP11A ALDH3B1 FPR2 TSPAN14 GPR84 ADAM10 P2RX1 ANO6 CYBA TMEM30A ITGAL RAB37	down	**
MIR10525_3P	0.0014347	0.0166637	0.4550599	0.4746119	1.788429	51	PCDHGA10 PCDHGA9 PCDHGA5 PCDHGA7 PCDHGA1 PCDHGB3 PCDHGA11 PCDHGA8 RANBP1 PCDHGA12 PCDHGB7 PCDHGA3 PCDHGA2 HMGN3 TJAP1 KIF20B SLX4IP ACLY ANKIB1	up	*
GO_4_IRON_4_SULFUR_CLUSTER_BINDING	0.0021448	0.0226533	0.4317077	0.5040323	1.788293	40	DDX11 PRIM2 POLE NDUFS2 BRIP1 ERCC2 TYW1 DNA2 POLD1 NDUFS7 NDUFV1 RTEL1 CDK5RAP1 NUBP2 RSAD1 NDUFS8 NUBPL CIAPIN1 CDKAL1 DPYD RSAD2	up	*
CARD_MIR302A_TARGETS	0.0004663	0.0069504	0.4984931	-0.3948510	-1.788268	67	WEE1 SASH1 TGFBR2 ASAP1 FOXJ3 RB1 SRSF2 KLF9 CCND2 SMAD7 MBD2 PHTF2 PPP6C JUNB DDX5 EPC2 TSHZ3 CDC37L1 CNOT7 RBL2 EPHA4 FOXJ2 ZFPM2 EIF4G2 CLOCK RB1CC1	down	**
GO_ENDOCRINE_PROCESS	0.0016711	0.0186574	0.4550599	-0.4144600	-1.787880	53	RAB11FIP1 ACE TBX3 IL1B HCAR2 RHOA FZD4 GATA3 CES1 TACR2 INHBA RAB8B CTSZ SUCNR1 MME CPA3 CRY1 EDN1 FGFR1 SMAD4 CYBA	down	*
IGLESIAS_E2F_TARGETS_UP	0.0000562	0.0011868	0.5573322	-0.3551799	-1.787540	121	LYL1 LPL CDC42 CD9 GAS6 LMNA CSRP1 BZW1 LCP1 CLK1 CES1 RHOB CFD LIMS1 ITM2B DAB2 ZFAND5 LAPTM5 CADM1 CCND2 CAPZA2 DSTN GNAI2 CALM2 ANXA3 CTSS C1QA CTSZ TYROBP DNAJA1 SERPINB6 CD34 MORF4L1 CACYBP PKD2 CD74 AKIRIN2 HNRNPA2B1 COL15A1 APLP2 ACADL NPTN TIMM22 CDKN1C NFKBIA ACADM	down	**
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_GRANULOCYTE_UP	0.0045157	0.0396935	0.4070179	-0.4311820	-1.787211	43	IL17RB TAL1 TIE1 HSPE1 HSPB1 JAM3 KANK2 SOCS2 MPL NPR3 SNN CDK17 GNAI1 MEIS1 MACF1	down	*
MIR938	0.0015771	0.0179203	0.4550599	-0.3949533	-1.787200	66	EPAS1 ZBTB34 SFR1 SLC11A1 MOB1B TRIB1 RCHY1 BZW1 HNRNPA3 DENND6A USP25 PRCP CREBRF MSRB3 IRF8 SDHD WDFY4 SLC8A3 CPT2 NPTN PRDM8 TIAM1 SSH2 SHISA6	down	*
GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_DN	0.0000868	0.0017097	0.5384341	0.4062277	1.787139	134	CECR7 IGF2BP3 PDCD2L SLC5A1 STK31 ENAM PTTG1 PLEKHA7 APOL2 KCNJ8 LIG3 AK8 GPX2 SIPA1L3 HAUS5 C6orf132 PPP1R9A C1orf220 FANCA APOL1 HORMAD1 SP140L ARHGEF34P PES1 MIPOL1 DCLK1 C2orf50 CDK12 IGHG1 ACSBG2 RANGAP1 ARFRP1 HNRNPA1L2 RHOC PSME2 OSBPL3 C19orf12 RGS22 SLC9C2 S100A13 HLA-A ZNF202 CDR2 TRIM56 ACTRT3 KPTN MYH3 TMEM253 ZNF257 GBP1 OXCT1 GBP2 VPS9D1 DNPEP ENPP5 CASC2 TRIB2 PIGL CLDN10 ENO1 E2F7 WIZ NLRC5	up	**
GSE3982_BASOPHIL_VS_TH2_UP	0.0000094	0.0002654	0.5933255	-0.3376390	-1.786963	169	EPAS1 ABHD5 OSBPL11 PECAM1 PTPRE FIG4 LYL1 PLEKHF2 ST3GAL6 AGTPBP1 EPB41L3 PILRA ANXA1 CD33 EIF1 NLK PTX3 SIRPA CLK1 ZFYVE16 BST1 DRAM1 TMED5 SOCS5 NPR3 CCSER2 PIK3C2A N4BP2L1 DSE PPP2R5A PAFAH1B1 TDRD7 TMOD1 PDCD6IP NECAP1 ARHGEF10 JAK1 PSTPIP2 RASSF2 RHOQ CALM1 MBP CHPT1 GSAP BAZ2B GALC MACF1 N4BP2L2 SERINC3 ARAP2 LRP12 CYB5R4 ACTB MEGF9 OSER1 KIT TMEM87A CREG1 DCUN1D2 UBAP1 SVIL OSGIN2 ZBTB7C PTGS1	down	***
GO_CENTROSOME_DUPLICATION	0.0017469	0.0192438	0.4550599	0.4608409	1.786899	58	PKHD1 CEP72 SPICE1 MDM1 BRCA1 BRSK1 STIL CCNF WDR62 POC1A C2CD3 CENPJ KIAA0753 CEP63 CEP192 TRIM37 SASS6 CKAP5 CHMP4C CDK5RAP2 CEP152 NUP62 ALMS1 CHMP1A CHMP2A	up	*
WANG_CISPLATIN_RESPONSE_AND_XPC_UP	0.0000525	0.0011265	0.5573322	0.4040405	1.786852	141	CEACAM1 TF TRIP13 DDX11 IGF2BP3 PTPRN2 GGCT PLEKHH1 TTK SLC27A2 KIF14 BCAS1 MMP1 YEATS4 FIGNL1 GLDC PAH NCAPD2 AP1G2 SMARCC1 AURKA POLA2 KIF11 LIG1 MAD2L1 PPP5C FADS2 BMP5 KRT18 CDK1 BIRC5 PCP2 PMEL FEN1 ATAD3A RNASEH2A FANCG TELO2 ILF2 COL1A1 KIF22 KIF21A POLD1 FXYD3 CDC7 ZNF502 KRT8 MYEF2 IGLL5 CNTN2 PYCR1 CDH1 RFC5 RAD51 TARBP1 MXD3 RPN1 UBE2C NCAPD3 TTLL5 NUP93 ANKRD11	up	**
GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_DC_DN	0.0000147	0.0003876	0.5933255	-0.3403136	-1.786064	167	CD52 PNPLA6 STAC PECAM1 OSBPL1A HHEX MNDA CLEC3B ATXN3 LTA4H RUNDC3B LYL1 LY86 NXPH3 FCER1A CIR1 FUCA1 TGFBR2 GGA2 TXNIP UBL3 ABCG1 APOC1 FBXL5 TNFSF12 ZCCHC24 CPVL ACTR3 PINK1 HTT ADD1 PRCP FRY LRRTM2 LAMB2 KCTD12 DNASE2 BAG5 CAP1 NDUFV2 PLCG2 FOS RIN2 CTNNAL1 ATXN1 DOK2 NPTN PLA2G15 GPX3 FKBP1A VASH1 WDR1 ESYT1 HSPA8 S100A4 METTL7A CD1E P2RX1 NRG1 RNH1 EVI5 INTS10	down	***
GO_RESPONSE_TO_MOLECULE_OF_BACTERIAL_ORIGIN	0.0000001	0.0000057	0.7049757	-0.3204428	-1.786040	272	SMAD6 CXCL3 SLPI ACP5 KMO IL1A SASH1 EDNRB SCIMP CD55 IL1B THBD LY86 MYD88 TBXA2R C5AR1 FGF10 IL1RN SLC11A1 TRIB1 CASP9 RHOA CD36 MIR146A CARD16 ADAM17 TNIP3 LITAF FOXP1 SIRPA TRAF6 PDE4D IL10 PTGIR CASP1 PTAFR LY96 CCL3 NFKB1 CXCL2 IRAK2 VIM SELP AXL TLR4 IL24 GNRH1 HCK CD80 IL6 JUN NOTCH1 CARD8 JUNB PTGER4 CCR7 IRF8 PRKCE PTGER2 MALT1 CXCL5 PLCG2 FOS PELI1 MAPK8 IRF5 TGFB1 AKIRIN2 CD6 IFNAR1 CD86 PLSCR4 KLRC4-KLRK1 PLAA PDE4B TSPO JUND ICAM1 IL18 TFPI TAB2 RIPK2 NLRP3 HAVCR2 NFKBIA EDN1 KLRK1 CSF2 CSF2RB SERPINE1 CNR2 CX3CR1 MAPK1 TREM2 S100A8 ZFP36 WNT5A SSC5D SHPK BCL10 CTR9 AKAP12 HMGB1	down	***
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	0.0000000	0.0000018	0.7195128	-0.3166266	-1.786003	299	TNR FFAR4 SIGLEC11 SEMA6B AJAP1 SEMA3G GPR17 SEMA6A ACP5 FOXF1 TEK PPARG ADTRP WFDC1 WNT4 THBD CDH5 SAMHD1 CLEC12B CALCRL HMGCR CD9 TRIB1 APOD SEMA6D MIR146A MYOZ1 SH2B3 CARD16 SEMA3B ADA ANXA5 RNF125 SERPINB9 GATA3 SIRPA RB1 GRN CRK WNT3A KANK2 PDGFA IL10 DUSP3 PTPRO MEFV KLF4 PLAUR THBS1 SOCS5 NFKB1 CDKN1A NR1D2 PTPRC DUSP1 UBASH3B PTGIS BACE1 KREMEN1 SOCS3 SEC14L1 PSMA1 NOTCH1 ETS1 CARD8 PTGER4 RTN4R CST7 CD34 YTHDF3 EPPK1 TREX1 CR1 SMPDL3B FPR2 YTHDF2 NLRP6 CNOT7 KLRC4-KLRK1 CLASP2 GPR18 SYT11 FGF2 TFPI ARRB2 SEMA4A EPHA4 NLRP3 HAVCR2 GRIN3A ADORA2A EDN1 KLRK1 PTEN PRKG1 RORA ITCH LDLR	down	***
GSE12366_GC_VS_MEMORY_BCELL_UP	0.0000181	0.0004631	0.5756103	0.3959819	1.785934	169	HELLS KIF20A GALNT14 MCM10 CENPF TIMELESS APOLD1 PBK DEPDC1B GINS1 CDCA2 TPX2 E2F3 UHRF1 MCM4 SPATS2 SLC35E3 MCM2 ARHGAP33 XPNPEP1 DTL ZNF608 SCG5 C5orf34 FBXO43 SAE1 MCM7 WDR78 CDCA5 RAD54L MCM3 WDR66 LMNB1 YEATS2 RNFT2 CHEK1 SPC24 PARP1 PSRC1 C12orf75 TMEM106C ENPP3 PEG10 SPAG5 ZNF827 NET1 DNMT1 ST14 TUBB2A TK1 CDC7 DNASE1 CDC20 CENPM ASRGL1 ROMO1 DPY19L2 LRIG1 ATAD2 CEP152 ESRRB SYBU RAD51 ZWILCH	up	***
GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN	0.0000029	0.0000979	0.6272567	-0.3384698	-1.785830	171	RTKN2 IL17RB PDLIM2 SGK3 GLIPR2 ANXA1 KIAA0355 DNAJC3 HBEGF PCYOX1 CLN5 PLXNA4 HNRNPDL TXN LINC00528 CASP1 SOCS2 MAFG TMBIM1 SELP UXS1 PLEKHB2 TDRD7 DDX60L CHDH ATP6V0B LYRM1 IDS PTGER2 TIGIT CLUHP3 KLF2 ICAM2 ABHD13 SBF2 IRS2 RIMKLB N4BP2L2 ZNF267 MEGF6 KAT2B HAUS3 CCR6 PDLIM5 CDC42EP3 CXCR4 TAB2 G3BP2 DNAJB9 CYTH1 NR3C2 LPAR6 IL16 TNFRSF10D ACVR1C CDC14A ITGB1 FTL SLC26A11 HLA-DRB1 CCDC93 ARHGEF12 RCBTB2	down	***
GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_UP	0.0000315	0.0007323	0.5573322	0.3969359	1.785828	164	KIF20A CDC45 ELOVL6 NPAS1 PSPH NDC80 RACGAP1 E2F8 ANLN TENM2 CDCA8 AURKB CENPA CDC6 CCNB2 UHRF1 PRC1 CCT6A CDT1 RANBP1 EXO1 NUDT1 KIF23 TOP2A POLA2 RRM2 MRPL27 CDC25C SOX4 RBP1 EGFR CHEK1 DNAJC9 ORC6 MAD2L1 AHCY GAS8 XRCC1 TULP3 CKS1B DRC1 NUSAP1 CDK1 POLE2 BIRC5 SRCIN1 EZH2 DIAPH3 COL1A2 KIF22 TK1 CENPK SLC26A1 CDC20 CKAP2 SURF2 LSM7 NFE2 RPS26 CCNA2 PRIM1	up	***
GO_CALCITONIN_FAMILY_RECEPTOR_SIGNALING_PATHWAY	0.0051509	0.0438331	0.4070179	-0.8363974	-1.785678	5	RAMP3 RAMP2 CALCRL	down	*
MIR200B_3P	0.0000000	0.0000002	0.7881868	-0.3050469	-1.785356	419	SLC24A4 RTKN2 NOVA2 FOXF1 DLC1 DENND5A OSBPL11 TRHDE SECISBP2L RDX MBOAT2 TMOD3 CORO1C VAT1L THAP2 QKI AKAP7 NR3C1 OTUD4 CBL SCN5A TMX4 ZEB2 ERG SEMA6D KIAA0355 DNAJC3 ASAP1 SERINC1 RANBP9 PICALM HIPK3 KLF6 PAG1 DACH1 KANK2 ZEB1 ZYG11B GPM6A FLI1 CPED1 PTPN12 ROCK2 PRDM16 PTPN21 CCDC82 KLF4 ZCCHC24 CLIC4 SPAG9 RECK WASF3 DUSP1 ELK3 ADIPOR2 GNAQ LIN7A AFF3 USP25 PDIK1L PHTF2 PIKFYVE JUN NOTCH1 HMBOX1 SLC14A1 ETS1 MAP4K4 OSTM1 FOXN2 TBC1D12 FERMT2 IPO7 HSPA13 PI4K2B MBNL2 ATL2 FSD1L CASZ1 PPM1F GAS2L3 AGFG1 CDK17 YPEL2 PKIA NAP1L5 ZFAND6 HNRNPD TIMP2 STRN PDS5B TSC22D1 KHDRBS1 NAB1 C16orf72 ATXN1 TOB1 KYNU CLASP2 SBSPON POLK ATAD2B RNF2 GEM SESN1 VASH1 XKR8 MGAT2 IER5 MFAP5 TRAPPC8 RIPK2 FBXO30 ARIH1 DIXDC1 ZDHHC21 ULK2 STK4 RASSF8 COPS8 SCAI B3GNT2 CECR2 DNAJB9 FAM126B PRKG1 CYTH1 MMD CAMSAP2 NRG1 ZFPM2 DNAJB5 EVI5 FEZ2 PMAIP1 ZNF326 REEP1 PSIP1 EXOG CRTAP CFL2 CLIP1 GJC1 HIPK1 FAM8A1 NOG CSNK1G3 CTDSPL2 YWHAB PRTG PPFIA1 UBE2W SGIP1 TSC22D2 MATR3 ADH1B MAP3K1 CNTN1 CCNYL1 NR5A2 RAB11FIP2 MPDZ LRP1 PKD1 MAPK7 SYDE1 NTF3	down	***
MIR200C_3P	0.0000000	0.0000002	0.7881868	-0.3050469	-1.785356	419	SLC24A4 RTKN2 NOVA2 FOXF1 DLC1 DENND5A OSBPL11 TRHDE SECISBP2L RDX MBOAT2 TMOD3 CORO1C VAT1L THAP2 QKI AKAP7 NR3C1 OTUD4 CBL SCN5A TMX4 ZEB2 ERG SEMA6D KIAA0355 DNAJC3 ASAP1 SERINC1 RANBP9 PICALM HIPK3 KLF6 PAG1 DACH1 KANK2 ZEB1 ZYG11B GPM6A FLI1 CPED1 PTPN12 ROCK2 PRDM16 PTPN21 CCDC82 KLF4 ZCCHC24 CLIC4 SPAG9 RECK WASF3 DUSP1 ELK3 ADIPOR2 GNAQ LIN7A AFF3 USP25 PDIK1L PHTF2 PIKFYVE JUN NOTCH1 HMBOX1 SLC14A1 ETS1 MAP4K4 OSTM1 FOXN2 TBC1D12 FERMT2 IPO7 HSPA13 PI4K2B MBNL2 ATL2 FSD1L CASZ1 PPM1F GAS2L3 AGFG1 CDK17 YPEL2 PKIA NAP1L5 ZFAND6 HNRNPD TIMP2 STRN PDS5B TSC22D1 KHDRBS1 NAB1 C16orf72 ATXN1 TOB1 KYNU CLASP2 SBSPON POLK ATAD2B RNF2 GEM SESN1 VASH1 XKR8 MGAT2 IER5 MFAP5 TRAPPC8 RIPK2 FBXO30 ARIH1 DIXDC1 ZDHHC21 ULK2 STK4 RASSF8 COPS8 SCAI B3GNT2 CECR2 DNAJB9 FAM126B PRKG1 CYTH1 MMD CAMSAP2 NRG1 ZFPM2 DNAJB5 EVI5 FEZ2 PMAIP1 ZNF326 REEP1 PSIP1 EXOG CRTAP CFL2 CLIP1 GJC1 HIPK1 FAM8A1 NOG CSNK1G3 CTDSPL2 YWHAB PRTG PPFIA1 UBE2W SGIP1 TSC22D2 MATR3 ADH1B MAP3K1 CNTN1 CCNYL1 NR5A2 RAB11FIP2 MPDZ LRP1 PKD1 MAPK7 SYDE1 NTF3	down	***
GO_OUTER_DYNEIN_ARM_ASSEMBLY	0.0051849	0.0439766	0.4070179	0.6860340	1.785301	12	DNAI1 ARMC4 CCDC114 DNAH8 LRRC6 DNAH5 CCDC151 DNAI2 ZMYND10 DNAAF1 DNAL1	up	*
GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_DN	0.0000361	0.0008220	0.5573322	0.3968971	1.785038	161	SLC2A1 TBRG4 PHGDH NIPSNAP1 TRIB3 PLS1 IKBKE NR2C2AP CHAF1A PAFAH1B3 MSX2 LARS2 PDCD5 AKAP1 TRPT1 AIMP2 SALL2 EEFSEC FNTB STXBP4 CXCL11 ISOC2 DDX51 PGBD2 PSAT1 GAL3ST4 PARS2 PDCD11 ZNF671 RAD51D DPH2 ZNF239 TRIM32 KRBA2 PEX10 TCEA2 ZFP69B PFAS TIMM13 L3MBTL2 SIRT4 RRP9 FAM50B ZSWIM8 SURF2 RAB15 ZBTB9 RCC1 LHPP FARSA ZNF224 AGMAT DTHD1 ABCF2 WDR77 ZNF71 EARS2 ROBO1 TMEM256 TMEM161A ALKBH2 PHRF1 CYHR1 ZNF511 SCRN2 PDK2 TMEM229B ZNF514 ZKSCAN4 LZTS2 MSH6 FCGBP NCOA5 ELP6 LFNG COQ4 IPO4 ZNF235	up	***
HU_GENOTOXIC_DAMAGE_4HR	0.0028040	0.0276232	0.4317077	0.5422744	1.784667	30	NEK2 ANLN PTTG1 ECT2 PRC1 CDT1 BUB1 AURKA CDC25C ZSCAN21 SMG5 KIF22 COMMD7 IFNAR2 HLA-A CDC20	up	*
GO_POSITIVE_REGULATION_OF_T_CELL_MEDIATED_IMMUNITY	0.0036680	0.0340128	0.4317077	-0.4366573	-1.784545	40	IL1B CD1C IL23A GATA3 IL18R1 TRAF6 FAM49B PTPRC IL6 STX7 MALT1 CD1D ZBTB1 CD81 FCGRT IL18 NLRP3 CD1E	down	*
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0004351	0.0065702	0.4984931	0.4303636	1.784536	86	HMGA2 TICRR BRCA1 BRSK1 PLK1 AURKB CDC6 ORC1 DTL ZFYVE19 CDK5RAP3 AURKA CLSPN TOPBP1 CHEK1 PSMD4 BLM CDK1 PSMB5 PSMC4 PSMA5 PSME2 FZR1 PSMD2 PSMB3 CHMP4C UIMC1 PSMB4	up	**
GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP	0.0000106	0.0002904	0.5933255	-0.3363104	-1.783621	182	SIDT2 FCN1 CD101 ASGR1 PECAM1 MNDA LTA4H CAT LY86 LMO2 SAMHD1 MYD88 P2RY13 AGTPBP1 FUCA1 FRAT1 CD36 DPEP2 CD33 ENTPD1 CD37 CST3 RHOB CFD KIAA0513 CPVL KLF11 PLBD1 SELL CD302 HK3 FOS KLF2 ICAM2 CD74 BIN2 CHPT1 CD1D CBFA2T3 RPL21 DOK2 RGS2 MBNL1 HELZ RBL2 CCDC69 CEBPD ALDH2 SCPEP1 S100A4 METTL7A ICAM3 GIMAP4 DUT PIEZO1 SLC35A1	down	***
GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_DN	0.0000080	0.0002304	0.5933255	-0.3385214	-1.782485	170	PECAM1 GLIPR2 PTPRE LMO2 MEF2A TXNIP KLHL30 ANXA1 CD5 SERINC1 IL18R1 TNS1 TAPT1 ITM2B RIT1 PLEKHB2 FCER1G ALOX5AP KLRD1 CD300LB MOB3A AFF3 SNN NRROS EMP3 SNX3 HPGDS NOTCH1 MN1 ATP6V0B TYROBP IFNGR1 RPS6KA1 TMEM167B DOCK8 FAM177A1 UVRAG CST7 WDR7 GPRIN3 ECI2 NKG7 CRYZL1 CBFA2T3 NAB1 ATP6V0C NQO2 GABARAPL1 DECR1 BMP2K SLC43A2 LDLRAD4 CALHM2 SRP72 HNRNPC ABI3 KIT DOCK10 PTEN EVI5 ARFGAP3 SLC35A1 CYBA TNFSF8 ITGAL MAMDC2 NCF1 TBC1D23 C6orf62 FXYD5	down	***
GO_PROTEIN_LOCALIZATION_TO_CYTOSKELETON	0.0020981	0.0222421	0.4317077	0.4704282	1.782411	52	CEP72 NUDCD3 TTK ANLN CCDC14 STIL GOLGB1 DCTN2 CEP250 BICD1 AURKA C2CD3 ABHD17C KIAA0753 SPAG5 CEP192 KIF20B	up	*
GO_ENDOTHELIAL_CELL_APOPTOTIC_PROCESS	0.0034434	0.0325331	0.4317077	-0.4293299	-1.782288	45	TEK GATA2 RAMP2 ECSCR BMPR2 GAS6 GATA3 RGCC NFE2L2 IL10 THBS1 MIR24-2 CD160 NDNF	down	*
GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_DN	0.0000211	0.0005246	0.5756103	-0.3395839	-1.782287	165	PECAM1 HHEX PTPRE LIPA FYN MMRN1 LMO2 ST3GAL6 TBXA2R NR3C1 SCARF1 ERG EDEM1 UBL3 ADA ITGA5 KLF10 GLS HLX ZFYVE16 PPP3CC ZMIZ1 KDSR EFCAB14 STX3 SOCS2 KLF7 CDS2 RECK ALOX5AP GNAQ AFF1 ARL6IP5 MAP4K4 AK1 GYPC PTGER2 SERPINB6 PPM1F ACSL1 FOXO3 BAZ2B PDE4B ETS2 SYT11 ARAP2 SLC31A1 SEC63 CALCOCO2 TMEM87A GPR171 THEMIS2 CREG1 BMI1 LYZ DMXL2	down	***
GO_POSITIVE_REGULATION_OF_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.0035303	0.0331227	0.4317077	-0.4714275	-1.781960	33	CD55 TGFBR2 IL23A ANXA1 HLX SOCS5 NCKAP1L CD80 CD160 CD83 MALT1 CD86 CD81 IL18 RIPK2 NLRP3	down	*
GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION	0.0000000	0.0000004	0.7614608	0.3618089	1.781704	458	PKHD1 MCIDAS CEP72 SPICE1 KIF20A MDM1 CHEK2 NEK2 CCNB1 KIF18B NDC80 BRCA1 TUBB2B TTK RACGAP1 BRSK1 SPAG17 ASPM STIL MSTO1 TTC26 CEP70 PLK1 NUF2 AURKB CENPA ESPL1 TPX2 GAPDH FIGNL1 MYBL2 PRC1 EFNA5 XRCC2 CCNF CIB1 DCTN2 SPDL1 DNAI1 HAUS5 RANBP1 CEP250 WDR62 RSPH1 ARMC4 DLG1 MAP7 KIF23 CUL9 SPAG16 CUL7 BICD1 KIF3B CCDC13 AUNIP MAP10 AURKA ODF2 TPR KIF2C CENPW POC1A HYDIN TEKT2 FSD1 HOOK1 CCDC114 WDR73 KIF11 GPSM2 DNAH8 CHEK1 IFT172 MAD2L1 GAS8 CLIP3 DNAAF3 C2CD3 TRPV4 SPRY1 PARD3 CCDC40 PSRC1 MARK1 CCDC78 KNSTRN DRC1 NUSAP1 PAK1 LRGUK LRRC6 CDK1 CROCC CEP97 CENPJ BIRC5 KIAA0753 SUN1 KIF19 KIF2A SSX2IP CCDC88C SPAG5 SAPCD2 DNAH5 PRKAA2 FGFR1OP KPNB1 CEP63 SPEF1 CEP192 TUBG1 DNAH7 NINL TACC3 LLGL2 CCDC151 TUBB2A IQCG TRIM37 TUBA8 SPAG1 MAP6D1 TRAF3IP1 DNAJB13 SASS6 CKAP5 CDC20 TUBG2 AAAS TTLL3 EFHC1 CHMP4C CDK5RAP2 DYNC1LI2 CKAP2 DNAI2 HAUS6 STMN3 KATNB1 SKAP1 TTLL6 RCC1 HAUS4 RSPH4A NEFH CEP152 CNTN2 NUP62 CEP85 ALMS1 APC2 ULK4 NTMT1 NAV1 TUBGCP4 DNAH1 HOOK2 TUBA4B CCDC88B CHMP1A MARK4 CHMP2A CHD3 CDK5 LLGL1 BCAS3 CAMSAP3 CENPE	up	***
MODULE_1	0.0000000	0.0000016	0.7337620	-0.3120833	-1.781466	320	SLPI PECAM1 CD55 CLEC3B EMP2 ENG CD44 CAV1 CITED2 TGFBR3 FUCA1 TGFBR2 RFTN1 HSPG2 HEG1 ANXA1 MAN2B1 LMNA CSRP1 KLF10 RNASE1 CAV2 NR4A1 NFE2L2 SFRP1 SRGN TFRC CNN1 TIPARP RHOB PTPN12 CFD SCP2 SRSF5 BIRC2 KLF4 AOC3 PEG3 DAB2 GMPR CCL3 CDKN1A KCNMB1 ATF3 CD302 PNRC1 IGFBP2 CCND2 PER1 ADIPOR2 WFS1 ACTG2 VAMP5 MYH11 PTGIS HES1 MAFF CRIM1 MAPRE2 VWF EMP3 IL6 SGK1 LAMB2 JUN MITF RAB31 LTBP2 JUNB RABGAP1 IFNGR1 PPP1R15A MFAP4 FSTL3 TNFRSF10B RASSF2 GFPT2 WDR7 CD34 CD151 FOS FOSB TIMP2 AOX1 PIM1 COL15A1 ORM2 FCGRT RGS2 LTBP1 CLEC2B MBNL1 SOD3 GEM GPX3 PDLIM5 CPQ LMOD1 CDKN1C BCAM MTUS1 FGFR1 LDLR IQGAP1 EGR1 SERPINE1 C1QB DUSP6 SVIL NR4A2 LHFPL2 ZYX EFS QSOX1 GNG11 AKAP12 DDX21 TES NFIL3 WWTR1 SLC23A2 ITGA6 PDPN LRP1 PKD1 DUSP2 FBLN1 EMP1 CHGA MYL9 ADAM19 MYLK	down	***
GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION	0.0038791	0.0354471	0.4317077	0.5752862	1.781383	24	PARPBP POLQ MAGEF1 TP53BP1 HELB BLM RECQL5 MAD2L2 UBQLN4 ZRANB3 MSH2 RTEL1 BCL6 MSH6 RMI2 MSH3	up	*
GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION	0.0001231	0.0022976	0.5188481	0.4140530	1.781183	114	TRIP13 BUB1B CCNB1 CENPF NDC80 PIF1 BRCA1 TTK DNMT3B PLK1 AURKB PTTG1 ESPL1 MCM2 CDT1 SPDL1 SDR16C5 BUB1 TOP2A TPR MAD1L1 MAD2L1 XRCC1 PIH1D1 PRMT6 MNAT1 PARP1 MAD2L2 KLHL22 DNMT1 NOC2L SLX4 RAD50 KDM3A CDC20 TWIST1 HMGA1 CDK5RAP2	up	**
GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_UP	0.0000089	0.0002535	0.5933255	-0.3399596	-1.780966	163	GPD1 ANGPT4 LPIN2 SASH1 SLC12A6 PECAM1 LMO2 CYB5R3 PLEKHA1 RCHY1 ABCB1 DNASE1L3 CLCF1 SIRPA UBE2D3 KRT4 EFCAB14 MEFV ST3GAL2 OSTF1 MYO1B EPM2A ITGAX UBE2E2 PTPRC ARHGAP9 B9D2 MATK RNF149 OXNAD1 HPGDS SLC14A1 HRH1 MED30 TREM1 RAB8A STX5 TUBGCP3 NDST1 YTHDF3 KANSL2 IST1 CCR6 TNFAIP8 RTN1 PIP4K2A ILKAP FNBP4 THEMIS2 USP48 FCRL1	down	***
CSR_LATE_UP.V1_UP	0.0000527	0.0011303	0.5573322	0.4028577	1.780895	143	TRIP13 FOXM1 CHEK2 CCDC34 PBK ANLN TOMM34 NUF2 YEATS4 CDCA8 CDC6 UHRF1 UMPS MYBL2 EIF3B ZWINT CASP2 C19orf48 FANCA EEF1E1 CLSPN RRM2 MCM3 ACTL6A DCTPP1 RAD18 PPP5C KRT18 CDK1 BIRC5 DCBLD1 GMNN POLR3K FEN1 EZH2 PA2G4 ILF2 TUBG1 LMNB2 YIPF3 KIF22 DTYMK NOC2L POLD1 PSMD2 CDC7 ASB6 CKAP2 GINS3 PRMT5 FARSA PRIM1 SHCBP1 FARSB ZWILCH CDK5 CIAPIN1 MTHFD1 PAICS UBE2C	up	**
MIR6757_3P	0.0004000	0.0061708	0.4984931	-0.3820284	-1.779826	81	SEMA6A USP12 EGR2 LDB2 PSMD5 UBL3 TTYH2 PPP2R2A GPM6A ATP6V1B2 PPP6R3 ARNTL SPAG9 KCTD20 N4BP2L1 ADD1 SIAH1 CPEB4 RC3H1 AZIN1 AKIRIN2 VAMP4 ATP6V1A ATXN1 CLASP2 MBD5 TBCEL SIN3A CAMSAP2 RORA	down	**
LANDIS_BREAST_CANCER_PROGRESSION_DN	0.0013781	0.0162501	0.4550599	-0.3958367	-1.779754	64	CLEC3B THBD ST3GAL6 QKI ALAS1 GAS6 FZD4 ZEB1 AHNAK SORBS1 BNIP2 KLF4 PDE8A ADIPOR2 PPP2R5A VWF CD34 GNAI1 DECR1 MFNG FEZ2 MAP4 PHYH GHR	down	*
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_10D_DN	0.0003091	0.0050122	0.4984931	-0.3521315	-1.779504	113	CXCL3 SLPI ACP5 ACE ADTRP PID1 FCER1A CHIT1 C5AR1 CD9 FUCA1 PLA2G7 RNASE1 DACH1 RGCC SGTB ID3 DAB2 SLC7A8 CCL3 RIT1 CXCL2 ATP6V0D2 CCL4 FRMD4A PTGER3 IL7R ANXA3 RPS6KA2 PDK4 SGK1 SLCO2B1 TMTC1 C1QA	down	**
GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN	0.0000201	0.0005052	0.5756103	0.3912861	1.778881	179	TG PSPH SLC2A1 DDIT4 PRIM2 BRCA1 ANLN NDUFS6 ACAD9 ALDH18A1 TRIB3 MCM2 XPNPEP1 XDH XPOT TAMM41 CISD1 KIF23 MKI67 PAFAH1B3 BUB1 TOP2A LMNB1 FAM162A LIG1 CHEK1 MAD2L1 RAD51AP1 CNPY2 CKS1B NUSAP1 CDK1 BIRC5 GMNN POLR3K MRPL17 PSAT1 TSPAN31 EZH2 SPAG5 TPD52L2 SNRNP25 DNMT1 ELMOD3 TUBG1 TACC3 SLC37A4 TRIM37 HIP1R SAP30 RAD50 CENPK CKAP5 CDC20 CKAP2 MCM5 HAX1 RCC1 PDIA4 HAUS4 STK39 UNC119B KLHL7 NDUFV1 RFC5 HK2 PGAM1 RPN1 DDX52 DTD2 LXN NCAPH CYB5B RNF14 UNC119 RCN2 MRTO4 PLK4 HRAS TRAFD1 CYTH3 APBA3 PTGR1 CCDC6 MLLT3 CMPK2 TIMM9 CRCP MTHFD2	up	***
BIOCARTA_AMI_PATHWAY	0.0054219	0.0453481	0.4070179	0.6833628	1.778350	12	PLAT FGA PROC FGG	up	*
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_UP	0.0000095	0.0002666	0.5933255	-0.3339011	-1.777071	177	LPIN2 SASH1 SWAP70 TSPAN4 HHEX RAMP2 CD44 LMO2 ESAM CLEC10A S1PR1 CD9 TGFBR2 ZEB2 ANXA1 NFIX CD33 IL18R1 CD93 MAP2K3 KLF4 STX3 SOCS5 TMBIM1 MARVELD1 UBE2E2 VIM C9orf72 SMAD7 VAMP5 PRDM5 PROCR PRCP MYO1C VAMP3 RNF149 ASNSD1 PSMA1 GLUD1 TYROBP PTGER2 CST7 RHOQ SERPINB1 CRYZL1 TSC22D1 ORC2 CD81 DOK2 MEIS1 PLA2G15 YAF2 ARRB2 KIT NFU1 THEMIS2 GRB10 MT2A EHD4 RNH1 FCRL1 NIPSNAP3A	down	***
GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_UP	0.0000411	0.0009199	0.5573322	-0.3470644	-1.776975	146	SLPI SECISBP2L CD55 LRRC8C ST6GALNAC3 FYN PLEKHA1 NEDD9 ZBTB2 ZEB2 LATS2 UNC45B CASP1 AIRN CCND2 DUSP1 GCA N4BP2L1 VAMP5 ZDHHC20 RPL17 TBC1D5 FRY NSMAF PHACTR2 PRAP1 DDX17 JUNB DAPK2 CD7 CST7 KLF2 FOXO3 NKG7 GIMAP1 ADPRM AKIRIN2 VAV3 BAZ2B TEC RGS2 SYT11 GEM RBL2 SERTAD1 SP100 ULK2 CD3G THEMIS2 TOX2 IRF2 PHYH CX3CR1 ING1 S1PR5 EP300 CD3E CCPG1 DOCK5 CD226 CCNC NIPAL3	down	***
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL	0.0000489	0.0010609	0.5573322	-0.3455078	-1.776272	147	CXCL3 SLC31A2 EREG BMP2 INSIG1 BDNF CD44 NEDD4L CITED2 LITAF KLF6 PTX3 KANK2 BTG3 TCF7L2 MCL1 TIPARP FOXO1 BIRC2 PLAUR ID3 THBS1 CDKN1A CXCL2 ID2 LBH DUSP1 INHBA MAFF TGFB2 IL6 JUN JUNB PTGER4 GLIPR1 CREB1 REL TNFRSF10B GPRC5A HIVEP2 GABARAPL1 TOB1 KYNU RGS2 RXRA CCL20 INTS6 NBN CALHM2 CEBPD DNAJB9 PDE8B LDLR PMAIP1 SPHK1 HERPUD1 SERPINE1 FJX1 HAS2 EFNB2 DNAJB4 HEY1	down	**
GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN	0.0000263	0.0006299	0.5756103	-0.3398038	-1.775973	162	CXCL3 EREG IL1A OLR1 IL1B EMP2 PTPRE CLDND1 NEDD4L CYB5R3 FXYD2 NCF2 IL1RN NUMB SLC44A2 ENTPD1 CSGALNACT2 RGCC SLC25A37 EVI2B MAP2K3 PAQR5 VASP PTPRC CXCL2 SELL CD53 FCER1G PIK3C2A EVI2A AFF1 CLN8 EMP3 RAC2 TREM1 PLK3 FAM43A CXCL5 FOS KLF2 PKD2 TSHZ3 PIK3AP1 FXYD6 NUP153 PDS5B TSPAN14 GPR84 ADPGK ETS2 CCL20 MIR155HG MS4A4A TAB2	down	***
GO_SPINDLE	0.0000002	0.0000106	0.6749629	0.3720797	1.775971	302	PKHD1 DDX11 SPICE1 KIF20A CEP89 BUB1B NEK2 CCNB1 CENPF KIF18B TTK RACGAP1 KIF14 ASPM PLK1 CDCA8 AURKB ECT2 ESPL1 CDC6 TPX2 TFDP2 PRC1 DYNC1I1 SPDL1 HAUS5 WDR62 RSPH1 KIF23 BOD1 KIF15 KNTC1 KIF3B AUNIP FBF1 MAP10 AURKA CBX3 ODF2 TPR SNCG MAD1L1 POC1A TTLL12 NSUN2 DCDC2 WDR73 KIF11 GPSM2 YEATS2 WDR60 TOPBP1 MAD2L1 CKAP2L SPAG8 ERCC2 PSRC1 INCENP KNSTRN NUSAP1 IQCB1 CDK1 DIDO1 BIRC5 KIF2A SPAG5 TTC23L POC1B RAB11FIP4 CBX1 MAD2L2 KLHL22 RANGAP1 MZT2A MZT2B CEP63 TUBG1 DLGAP5 TACC3 KIF22 PKP4 CLTA KIF20B NUP85 CEP128 JTB POLB CDC7 TADA3 CENPV CKAP5 CDC20 TUBG2 AAAS EFHC1 CDK5RAP2 CKAP2 HAUS6 FAM161A KATNB1 HAUS4 NUP62 CEP85 MICAL3 ALMS1 SHCBP1 TUBGCP4 NUBP2 AGBL5 CTTN CENPE E4F1 GOLGA2 CDC25B DCDC1 MAP9 CLASP1 TMEM201 UNC119 DNAAF1 MAK KLHL42 PLK4 FAM110C PRPF19 DSN1 FBXO5 TUBGCP2 KIFAP3 MAD2L1BP NPM1 PARP4 RCC2	up	***
GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN	0.0000268	0.0006393	0.5756103	0.3885959	1.775730	182	TRIP13 PSPH PRIM2 BRCA1 METTL1 ANLN NDUFS6 ACAD9 ALDH18A1 MCM2 XPNPEP1 CCT6A XPOT TAMM41 NUDT1 CISD1 KIF23 MKI67 TOP2A LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD CNPY2 CKS1B MRPL37 CDK1 BIRC5 CCT3 GMNN POLR3K MRPL17 TSPAN31 EZH2 CBX1 NOP2 TPD52L2 DNMT1 TUBG1 TACC3 MNS1 TRIM37 DUSP12 NUP85 POLB RAD50 CENPK CKAP5 RRP9 RPL7L1 MCM5 HAX1 RCC1 PDIA4 HAUS4 KLHL7 RFC5 PDAP1 WDR77 INO80E HK2 PGAM1 SPR RPN1 POLR1A CHERP DTD2 DDX41 CYB5B RCN2 MRTO4 LUC7L3 SRM PLK4 HRAS MRPL2 COQ5 GCSH ABCD3 PPA1 TIMM9 CRCP MTHFD2	up	***
GAVIN_FOXP3_TARGETS_CLUSTER_P7	0.0004274	0.0064846	0.4984931	-0.3810747	-1.775383	81	SOSTDC1 DENND5A GLIPR2 ST3GAL6 BMPR2 MSRA AGPAT4 ABCB1 ANXA1 FAM89A RGCC IL10 SOCS2 ITIH5 SELP SHE PRF1 EVI2A KLRD1 SNN	down	**
GO_5_3_DNA_HELICASE_ACTIVITY	0.0019469	0.0210134	0.4550599	0.8008267	1.775094	7	RUVBL1 PIF1 RUVBL2 HELB ERCC2 DNA2 IGHMBP2	up	*
GO_CHEMOKINE_PRODUCTION	0.0005323	0.0077412	0.4772708	-0.3919369	-1.775070	67	HMOX1 IL1B LPL IL1RL1 APOD MIR146A ADAM17 CLEC7A FOXP1 SIRPA IL10 MEFV KLF4 SOCS5 TLR4 IL6 MBP CD74 CHIA IL18 RIPK2 HAVCR2 EPHA2 MCOLN2 EGR1 C5 TREM2 S100A8 MUL1 WNT5A	down	**
GO_NEGATIVE_REGULATION_OF_LIPID_STORAGE	0.0059446	0.0485953	0.4070179	-0.5631290	-1.774771	17	ABHD5 PPARG MIR146A ABCG1 IL6 PNPLA2 NFKBIA	down	*
GSE23925_DARK_ZONE_VS_NAIVE_BCELL_DN	0.0000190	0.0004812	0.5756103	-0.3381426	-1.774670	167	EGR2 VAMP2 BCL2A1 TRIB1 IER2 CCNL1 SH2D6 PPP1R15B CSRP1 GATA3 NR4A1 JAM3 SRGN MAPK8IP1 BTG3 EIF1B CSRNP1 ITPRIP PTPN21 CASKIN2 ID3 STK17B CCL4 PNRC1 PER1 DUSP1 ELMSAN1 SH2D2A MAFF MOB3A SRF ETF1 SENP3 ETV3 ARL5B PLK3 JUNB KLHL18 EGLN2 SLC3A2 FOS FOSB DUSP5 AOX1 ATP6V0C MFNG TMA7 KTI12 UNC13D GEM SELPLG TOB2 ISCU GPR171 CCND3 HPCAL4 MED31 PIM3 EGR1 DUSP6 NR4A2 EYA3 ZFP36 YRDC CD69 DNAJB1 BCL10 TRMT10C NCOA7 NFKBIZ KBTBD2 DUSP2 ZCCHC14 FBXO33	down	***
GO_INTRACILIARY_TRANSPORT	0.0026343	0.0263085	0.4317077	0.4838010	1.774341	46	IFT122 TTC26 IFT27 KIF3B IFT43 WDR60 IFT172 KIF3C SSX2IP DYNLL2 LCA5 IFT52 TRAF3IP1 WDR34 WDR35 DYNC2H1 ICK CLUAP1 TTC30B MAK KIFAP3 BBS12 KIF3A IFT81 IFT74 TCTEX1D2 SSNA1 IFT80 TTC30A LCA5L TUB IFT57 IFT140	up	*
GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX	0.0024065	0.0246840	0.4317077	0.5462926	1.774276	28	LSM5 PRPF6 SNRPE EFTUD2 SNRPD1 LSM7 LSM4 TXNL4A PRPF18 SNRPD2 TXNL4B USP39 PRPF31 SNRNP200 ZMAT2 PRPF3 SART1 SART3	up	*
GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_UP	0.0000098	0.0002749	0.5933255	-0.3348825	-1.774198	173	CXCL3 EREG IL1A CD55 IL1B CLDND1 PID1 COQ2 BCL2A1 SLC11A1 STARD4 ATP2B1 PTPRM CARD16 ADAM17 EIF1 SWT1 RAB33B MPHOSPH6 TCF7L2 TMEM38B AGO3 CASP1 PLAUR SOCS2 CXCL2 ALOX5AP PINK1 OXSR1 IL24 KREMEN1 STK24 PKIG FMNL2 FLT1 DDX60L RNF149 SH3BP5 CELF1 CARD8 PNPLA8 ZBED5 CDK14 SNX9 HIVEP2 TGIF1 FAM228B TEX30 DUSP5 RIMKLB INO80D CCL20 BNIP3L CDC42EP3 GIMAP5 BCAT1 RAB2B	down	***
LOPEZ_EPITHELIOID_MESOTHELIOMA	0.0037903	0.0348099	0.4317077	0.6339031	1.773931	16	HP PRR15L GRB7 GPR37 CLDN15 LRP2 ELMO3 UPK1B ANXA9 PTPRF	up	*
GO_POSITIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0029706	0.0289195	0.4317077	0.5526304	1.773870	27	CCNB1 STOX1 CDK4 DBF4B CDC25A DTL SMARCD3 CDC25C CDK1 MTA3 ATAD5 CDC7 WNT10B CDC25B FBXO5 NPM1 RCC2 BRD4	up	*
TTCCGTT_MIR191	0.0046469	0.0404719	0.4070179	-0.4896104	-1.773544	26	BDNF FOXP1 ZCCHC24 TJP1 CCND2 RNF139 OXSR1 PLCD1 LIN54 NDST1 AP1G1 TMOD2 EGR1	down	*
STEARMAN_TUMOR_FIELD_EFFECT_UP	0.0044279	0.0391022	0.4070179	-0.4748274	-1.773297	30	ACP5 LPL LILRB3 SIRPA APOC1 MPEG1 CTSD ITGAX CTSS SOCS3 CTSZ	down	*
GSE24142_DN2_VS_DN3_THYMOCYTE_UP	0.0000095	0.0002657	0.5933255	-0.3366943	-1.772864	170	CD52 IL17RB TSPAN4 TAL1 HHEX PTPRE LYL1 SH2D3C CD44 MYADM AQP9 CLEC10A CD9 ANXA1 LACTB HBEGF GM2A LITAF SRGN SPI1 RHOB SLC7A8 ITGAX VIM CD302 PTGER3 ALOX5AP MAPRE2 PROCR CABLES1 RGS18 TAS1R1 CD48 RAB31 TYROBP GLIPR1 SELENBP1 PI4K2B HSD17B12 OGFRL1 TAGLN2 CST7 CD34 CD151 SLC25A24 CPA3 IRF5 VAV3 SERPINB1 CRYZL1 CTNNAL1 PIM1	down	***
GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_DN	0.0000235	0.0005738	0.5756103	0.3899265	1.772700	179	TRIP13 KIF20A HJURP BUB1B CENPF PBK DDIT4 PRIM2 STIL PLK1 AURKB TPX2 MCM2 XPNPEP1 NCAPD2 CLPTM1L MELK CISD1 MKI67 TOP2A SAE1 MCM7 MPO KIF11 MCM3 CHAF1B LIG1 MAD2L1 AHCY RAD51AP1 INCENP TMED3 CKS1B NUSAP1 CBX5 HDGF RFWD3 GMNN GOT2 DNA2 SDCBP2 TSPAN31 ETFB DIAPH3 CCNE1 DPP3 DLGAP5 FANCF SNRPA TRIM37 DTYMK MRPL4 ANP32E CENPV CDC20 POPDC2 PELO MCM6 SRSF1 LRRK1 STK39 APOBEC2 ZWILCH TBCB SMC2 RPN1 MTHFD1 ZBTB32 NDUFB7 COX17 ACSL5 ESM1 ACSBG1 SLC38A10 PLK4 FAM120A	up	***
GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP	0.0000129	0.0003471	0.5933255	-0.3346657	-1.771227	169	EPAS1 ACE SLC47A1 PECAM1 ZC3H12C FBP1 CLEC10A MSRA MKNK1 NCF2 ANAPC15 SPCS3 DNASE1L3 ASAP1 SGMS2 TACC1 LMNA ABCG2 BTG2 PARVG PTX3 C1orf162 CD93 TAPT1 MAP2K3 PPT1 PRKD3 ABCC4 TM6SF1 HTT PEAK1 UBASH3B ARHGDIB CYB5R1 SNX29 GLIPR1 GMFG ATP13A3 HOMER1 CLN3 SRSF6 TPMT STX12 PLEKHO2 MBNL1 RXRA ABL2 CDC42EP3 ESYT1 ALDH6A1 MEGF9 GPD1L S100A4 ICAM3 CBX7 ZNF106 ATP11B PLXDC2 ATP1B1 PTGS1 FXYD5 NXN ATP8A1 SKAP2 NCOA7 TTC39B NFKBIZ CYP1B1 GALM GSN PYCARD UQCRB	down	***
MIR363_3P	0.0000000	0.0000019	0.7195128	-0.3066581	-1.770853	363	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 MED19 SLC7A11 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 KBTBD8 MORC3 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 ZNF521 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 FAM126B MMD C21orf91 RORA EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 MEF2D ZFYVE21 ITGA6 ROBO2 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1 NFYB MYO5A ADCY3 ANKRD44 ADAM19 MFHAS1 SLC24A3 PNISR PSMD14 KLHL29 PIK3R3 RBM27 ANKRD28 ZC2HC1A AIDA GTF2A1	down	***
SRF_Q5_01	0.0000069	0.0002026	0.6105269	-0.3330153	-1.770812	176	PPARG TMEM126A LRRFIP1 EGR2 CORO1C MYADM CITED2 IER2 KCNK3 CSRP1 EMILIN2 PICALM FOXP1 KLF6 LCP1 CNN1 TRIM46 YBX3 VASP THBS1 NPR3 ATF3 ACTR3 DSTN ACTG2 MYH11 SRF GPBP1 SGK1 PODN MITF JUNB RHOJ CXCL5 RASSF2 COL23A1 FOS KRTCAP2 FOSB DGKG FLNC AKIRIN2 DUSP5 TGFB1I1 C16orf72 MRGPRF TAGLN MBNL1 PDLIM5 DIXDC1 PTCH1 ACTB G3BP2 TIMP3 CNN2 RSU1 ATF4 STARD13 EGR1 CFL2 CDKN1B FAM131B SVIL ADAMTSL1	down	***
GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN	0.0001249	0.0023244	0.5188481	0.4023195	1.769945	134	CPNE4 FOXM1 KIF20A BUB1B CCNB1 CENPF PBK RGMB-AS1 GINS1 E2F8 KIF14 STK31 CEP70 NUF2 CCNB2 MCM2 TYMS GRHL3 GLDC DTL KHDC1 ZWINT CLPTM1L HMMR CEP55 SDHA MKI67 EMC9 KIF15 AURKA IGLV1-44 MSX1 RRM2 ANKRD16 SPC24 WWC1 CDK1 DMGDH NCAPG STEAP1 SPAG5	up	**
chr3p22	0.0003964	0.0061300	0.4984931	-0.3698082	-1.769570	89	TRIM71 STAC VIPR1-AS1 SEC22C MYD88 UBE2FP1 SCN5A LRRFIP2 EPM2AIP1 EIF1B CSRNP1 RPL21P135 MYRIP SS18L2 WDR48 OXSR1 PLCD1 TPMTP2 CMTM6 GLB1 NDUFAF4P3 PDCD6IP UBE2D3P2 TMPPE SNRK CCR4 ITGA9 RN7SL517P DYNC1LI1 CLASP2 XIRP1 CNOT10-AS1 TTC21A GPD1L DDTP1 EXOG CRTAP SLC25A38 CX3CR1	down	**
GO_SM_LIKE_PROTEIN_FAMILY_COMPLEX	0.0017138	0.0190017	0.4550599	0.4469867	1.768615	63	LSM5 GEMIN7 GEMIN4 PRPF6 SNRPE EFTUD2 SNRPA GEMIN5 GEMIN6 CD2BP2 SNRPD1 LSM7 DDX23 LSM4 TXNL4A SF3A2 PRPF18 SNRPD2 TXNL4B USP39 PRPF31 SNRNP70 SNRNP200 ZMAT2 PRPF3 SNRPC SF3B2 SART1 SART3 GEMIN2 CLNS1A LUC7L3	up	*
GSE3982_NKCELL_VS_TH2_DN	0.0000180	0.0004606	0.5756103	0.3901655	1.768067	175	KIF20A FANCI GGCT KIF18B TSFM STIL CENPA PTTG1 ESPL1 SFXN1 E2F3 CCNB2 RBBP8 TYMS CDC25A DTL CCT6A GINS4 NCAPD2 COQ3 LDHB MRPL15 AURKA POLA2 KIF2C RRM2 PDCD5 RAD54L MRPL3 KIF11 MDM2 INPP4B SYMPK NOL3 CKS1B NCAPG2 NUSAP1 TMEM106C SSBP1 POLE2 BIRC5 C1orf112 GMNN NCAPG PSMB5 SNRPE RTCB LONP1 GINS2 KIF20B DAP3 CCT7 CKAP2 UTP20 MCM5 HEATR1 TDP1 SRSF1 ATAD2 MSH2 CCNA2 HK2 RAD51 LRRC8B GRAMD1B RPUSD2 TNS3 SMC2	up	***
FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP	0.0007178	0.0098253	0.4772708	-0.3844000	-1.767949	73	FGR GATA3 SPTBN1 TLE4 YBX3 FUT7 ID3 LAPTM5 VIM SELL DSTN BTG1 TRGC2 DDX5 CD34 MME TCF4 TSC22D1 FCGRT SPOCK2 SERINC3 CLEC2B TIAM1 CCR9 SREBF2 BMI1 CTSH CX3CR1 TUBA1A CD3E NFIL3 IL32	down	**
GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN	0.0000469	0.0010278	0.5573322	0.3928039	1.767693	163	TRIP13 GMDS TROAP CENPF POLQ NUDCD3 ANKZF1 ALDH18A1 FIGNL1 STC2 UHRF1 HPS3 RCCD1 MAGEF1 RUVBL2 HLTF FSD1 B3GNTL1 BRI3BP SLC9A3R1 THYN1 CBY1 PIH1D1 BRIP1 FNTB PHB DLG5 FGGY C12orf75 ASF1B UCK2 ATIC POLR3K ZNF775 MAD2L2 DIAPH3 ITPR3 ZNF692 PIAS3 MRPS34 MRPL11 MTA3 PINLYP FUCA2 DHTKD1 P4HA1 TIMM13 CENPM ACLY RABEPK SNAP47 GINS3 HAUS4 DPH5 SUV39H2 ABHD10 GBP2 CDK5 WDR76 ETHE1 PCBD1 NCAPD3 DDB2 CYHR1 AKR7A2 HEXIM2 MRPS16 PM20D2 FAM120A JAKMIP2 SRI PSMB10	up	**
KEGG_HOMOLOGOUS_RECOMBINATION	0.0039940	0.0361780	0.4070179	0.5636300	1.766989	25	RAD54B XRCC2 TOP3B EME1 POLD2 RAD54L BLM SSBP1 RAD51D POLD1 RAD50 RPA1 RAD51 MUS81 TOP3A	up	*
ATACTGT_MIR144	0.0000114	0.0003119	0.5933255	-0.3337019	-1.766057	172	SEMA6A CPEB2 ST6GALNAC3 CCDC88A CALCRL QKI ZCCHC2 NR3C1 TRIB1 ZEB2 SEMA6D UBR3 ATP2B1 LIFR EIF5 CAV2 SLC7A11 GATA3 NFE2L2 SFRP1 CLK1 HNRNPU ITSN2 PDE4D UBE2D3 TFRC FOXO1 FBXL3 PNRC1 PAFAH1B1 FAM76B MTPN CREBRF PKNOX1 PHTF2 ETS1 JPH1 WTAP KBTBD8 CELF2 PTP4A1 FOSB RIN2 CC2D2B KIAA0232 PIM1 ATXN1 PPP3R1 MEIS1 SRSF10 SIN3A FAM126B NRP2 NAA15 GSPT1 WDFY3 PUM1 EIF4G2 HAT1 PLAG1	down	***
GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN	0.0000238	0.0005805	0.5756103	-0.3325621	-1.765184	180	EPAS1 NLRC4 EREG CD300LF CD52 ABHD5 DENND5A DCSTAMP LPXN ENG PRAM1 ARIH2OS FLVCR2 GPCPD1 TBC1D2 LAMP1 FGR GGA2 CASP9 DNAJC5B ADAM17 ABCG2 FAM89A ABHD6 APOC1 LCMT2 BST1 PLBD1 CTSD ATF3 TLR4 MFSD11 WFS1 IL7R FKBP15 HEXB CABLES1 NXPE3 PRKCE SIGLEC15 SERPINB6 ACSL1 GPRIN3 HIVEP2 CR1 PNPLA3 MME TGFB1 CD1D TSC22D1 TMEM230 APLP2 GABARAPL1 FCGRT DECR1	down	***
CROSBY_E2F4_TARGETS	0.0023307	0.0240611	0.4317077	0.8376507	1.765066	6	BUB1B NDC80 PTTG1 CDC6 CHEK1	up	*
GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN	0.0000137	0.0003653	0.5933255	-0.3334912	-1.765011	169	CXCL3 EREG SPN CLDND1 EGR2 HCAR2 PRPF38A STX11 MARCO TSHZ1 TRIB1 HEG1 TMPRSS6 ITGA5 TNIP3 TMEM123 SLC7A2 PTPN12 TAPT1 BIRC2 TNFSF15 DRAM1 TMED5 RMDN3 ITGAX GPR85 GCA N4BP1 PIK3R5 HTRA4 KREMEN1 TDRD7 PROCR FMNL2 PPP2CA PHTF2 DDHD1 PNO1 APPL1 CPEB4 SHOC2 DUSP8 HSD17B12 ECI2 TAGAP GPR18 AMD1 IL18 VASH1 WDR1 XKR8 EPHA4 RIPK2 MEX3C POLR2M SDAD1 ZDHHC5 SAMSN1 MIER3 SPATA13 SLC16A10 ABI1 SERPINE1 ITGAL DCUN1D3 DYNC1I2 PIK3CG	down	***
GO_GLYCOLYTIC_PROCESS_THROUGH_FRUCTOSE_6_PHOSPHATE	0.0028907	0.0282764	0.4317077	0.5896908	1.764990	21	PGM2L1 GPI GAPDH ALDOC PKM PFKP ALDOA ALDOB BPGM FOXK1 HK2 PFKM PGAM1 ENO1	up	*
GO_AMEBOIDAL_TYPE_CELL_MIGRATION	0.0000000	0.0000012	0.7337620	-0.3096047	-1.764799	345	ANGPT4 SEMA6B SEMA3G SEMA6A ACVRL1 SASH1 HMOX1 SOX18 TEK EDNRB PECAM1 PPARG ADTRP GLIPR2 GATA2 EMP2 BMPER FOLR1 SOX17 BAG4 CORO1C CDH13 BMPR2 TBXA2R FGF10 MIR27B TGFBR2 RHOA ZEB2 SEMA6D ANXA1 MIR146A MMRN2 PTPRM SEMA3B HBEGF ARSB ADAM17 CLEC14A HSPB1 FOXP1 ADIPOR1 GATA3 NR4A1 RGCC NFE2L2 TNS1 GRN AKT3 KANK2 FOXC2 NODAL RHOB MAP2K3 ROCK2 STAT5A AMOTL1 TNFSF12 KLF4 ZFAND5 THBS1 ADAMTS9 MIR24-2 PIK3C2A PAFAH1B1 NUS1 ANXA3 MAPRE2 ARHGDIB TGFB2 SRF PRCP KANK1 SLC8A1 WASF2 APPL1 JUN NOTCH1 ETS1 MAP4K4 RHOJ PRKCE CAP1 PPM1F PLCG2 EPPK1 WNT11 TGFB1 MIR23A CYGB TGFB1I1 MIA3 CLASP2 MACF1 CCR6 FGF2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 SP100 EPHA2 GLUL RET KIT EDN1 PTEN FGFR1 NRP2	down	***
GSE26290_CTRL_VS_AKT_INHIBITOR_TREATED_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN	0.0000102	0.0002826	0.5933255	-0.3317875	-1.764107	175	IL17RB ASGR1 HVCN1 HMGCR BCL2A1 CD9 MOB1B HEG1 LACTB LMNA MAP3K8 CSGALNACT2 PAG1 LAIR1 C1orf162 PLXNA4 PDE4D KPNA5 ADARB1 ARRB1 ITPRIP SGTB SDCBP PLAUR DOCK9 RIT1 HOPX FXYD7 UBASH3B PTGIS COPS4 FOXN3 NRROS SERTAD2 ARHGAP17 SPIN1 RAB8B CD48 ETV3 GAS2L1 MPZL3 PSTPIP2 OSM MORC3 SIGLEC17P MBP MSMO1 ZNF575 GIMAP1 RELL1 TAGAP STK40 JUND IL18 TNFAIP8 CALCOCO2 HAVCR2 S100A4 SCAI SAMSN1 TLK1 MAN1C1	down	***
GO_KINETOCHORE_ORGANIZATION	0.0027539	0.0272129	0.4317077	0.6047727	1.764054	19	CENPF NDC80 NUF2 CENPA CDT1 CENPW CENPH TRAPPC12 CENPK CENPT SMC2 CENPE POGZ	up	*
GO_RESPONSE_TO_WOUNDING	0.0000000	0.0000000	0.8266573	-0.2926778	-1.763951	527	TNR AJAP1 CLEC1B EREG ACVRL1 IL1A FOXF1 HMOX1 PECAM1 CCM2L ADTRP HHEX GATA2 WFDC1 F2RL3 WNT4 P2RY1 LYVE1 THBD RCOR1 TRPC3 FOLR1 FYN MMRN1 CD44 CAV1 TBXA2R HMGCR FGF10 PRKAR1A CDC42 CD9 GAS6 SLC11A1 TGFBR2 SCARF1 HPS5 PEAR1 RHOA APOD CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 ADAM17 ENTPD1 CLEC7A CSRP1 ITGA5 HSPB1 ANXA5 SLC7A11 GATA3 PPP3CA JAM3 NFE2L2 NDEL1 GRN CRK WNT3A SGCA PDGFA FOXC2 PTPN12 GPR4 IL10 ARRB1 DGKE KLF4 PLAUR ID3 THBS1 MAFG MPL ITPK1 DOCK9 CDKN1A SELP AXL HPSE TLR4 CAPZA2 FCER1G ELK3 PLEK ADIPOR2 MATN2 GNAQ UBASH3B PIK3R5 C4BPB MAFF IL24 AKIRIN1 KREMEN1 VWF TGFB2 STK24 PROCR MTPN SRF NINJ1 PRCP KANK1 CNTF METAP1 IL6 LAMB2 NDNF JUN NOTCH1 ETS1 TYROBP DUOX1 ENPP4 IFRD1 PIK3R1 PABPC4 PRKCE RTN4R PRKACA DOCK8 AP3B1 YWHAZ MCAM CD34 PLCG2 CD151 EHD2 SRSF6 PRKCG EPPK1 MYL12A DGKG STXBP3 TGFB1 EHD1 VAV3 ITGA9 TEC NLRP6 MIA3 CD81 CCR1 CLASP2 GATA6 GNA13 MACF1 TSPO SMAD2 DOCK6 SYT11 FGF2 CPQ VASH1 TFPI ARRB2 RAB5A CXCR4 EPHA4 ACTB ADORA2A JMJD1C MAFK EDN1 SCUBE1 PTEN PRKG1 P2RX1 NRG1 ZFPM2 EHD3 ANO6 PAPSS2 IRF2 SERPINE1 CDKN1B FKBP1B TREML1 CAPZB CX3CR1 MAPK1 PRKCH MYH10 S100A8 ZFP36 CD109 NOG	down	***
GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN	0.0000734	0.0014909	0.5384341	0.3940975	1.763694	156	TRIP13 BRINP1 CNGA1 MDM1 PMFBP1 BUB1B NUP107 NDC80 PRIM2 GTSE1 ECT2 WDR70 RBBP8 MCM4 SP5 CHRDL2 DTL NCAPD2 STRA6 IDO1 CEL MAD1L1 TPCN1 TEKT2 FAM216B MCM3 ASS1 ZNF786 C7orf50 RAD51AP1 KNSTRN MB KCNE3 POLR3K NPM3 NCAPG SCTR CCDC88C SPAG5 NF1 TACC3 ARF5 DBN1 ATG9B TEKT3 SRD5A3 SAP30 MAT1A ANKRD6 PELO CDK5RAP2 MCM6 ZNF446 IFITM10 CUBN PDIA4 AKAP6 PRR11 MEP1B WDR76 SIGMAR1 UBE2C ADARB2 MSRB1 B3GNT4 PLIN5	up	**
CHEN_ETV5_TARGETS_TESTIS	0.0023955	0.0246007	0.4317077	0.6159720	1.763569	17	HELLS AK4 CDCA7 MCM2 MKI67 HAUS6 RAD51 RBL1	up	*
GSE7852_THYMUS_VS_FAT_TCONV_DN	0.0000130	0.0003481	0.5933255	-0.3321996	-1.763422	178	LPXN PTPRB SIK1 RUNDC3B CAV1 MYADM BCL2A1 AGPAT4 B3GNT5 LATS2 ZDHHC2 LUZP1 LITAF IL18R1 CD93 BTG3 IL10 CFD AGO3 DGKE STX3 TMBIM1 NR1D2 SIK2 ATF3 HOPX PLEK ARL4A CPT1A SPRYD7 BCLAF1 MAFF CRIM1 MAPRE2 FLT1 TAS1R1 SNHG8 PPP1R15A PTGER4 REL DENND4A TAGLN2 CST7 RRAS HIVEP2 MBP RUNX3 FOSB AKIRIN2 TEC TSC22D1 RELL1 RGS2 BMP2K ITPRIPL2 CDC42EP3 CXCR4 TAB2 DAPK1 DNAJB9 SAMSN1 LDLR NAF1 SLC38A2 EFNB2 TSC22D2 ATP2B4 NFIL3 ATF6 IMPACT MRPL16 AKAP13 NFKBIZ GZMB MYO1F ZCCHC14 PNP PLXNC1 KLRG1	down	***
WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP	0.0023955	0.0246007	0.4317077	0.6159037	1.763373	17	POLQ GTSE1 PLK1 CBX3 NCAPG2 FEN1 UCKL1 SUPT16H ATAD2	up	*
GO_INTERSTRAND_CROSS_LINK_REPAIR	0.0025222	0.0255745	0.4317077	0.4800324	1.762973	45	FANCI UBE2T MCM8 FANCA EME1 ATR FANCD2 RAD51AP1 POLN RFWD3 FANCG DCLRE1C FANCF RAD51D SLX4 RPA1 FANCM RAD51 MUS81 ATRIP RNF8 DCLRE1B MSH6 DCLRE1A	up	*
MIR367_3P	0.0000000	0.0000011	0.7337620	-0.3037946	-1.762841	364	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 MED19 SLC7A11 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 KBTBD8 MORC3 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 ZNF521 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 FAM126B MMD C21orf91 RORA EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 MEF2D ZFYVE21 ITGA6 ROBO2 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1 NFYB MYO5A ADCY3 ANKRD44 ADAM19 MFHAS1 SLC24A3 PNISR PSMD14 KLHL29 PIK3R3 RBM27 ANKRD28 ZC2HC1A AIDA GTF2A1	down	***
GO_NAIL_DEVELOPMENT	0.0022535	0.0234341	0.4317077	0.7952929	1.762828	7	MSX2 ITGB4 MSX1 RSPO4	up	*
GO_INOSITOL_1_3_4_5_TETRAKISPHOSPHATE_5_PHOSPHATASE_ACTIVITY	0.0051883	0.0439909	0.4070179	-0.8891742	-1.762690	4	INPP5K INPP5A	down	*
REACTOME_CA2_PATHWAY	0.0018428	0.0200752	0.4550599	-0.4020629	-1.762563	57	PRKG2 GNGT2 NLK FZD4 PPP3CA GNG7 TCF7L2 AGO4 AGO3 PDE6A PDE6B CALM1 WNT11 GNG5 PPP3R1 GNB4 TCF7L1 PRKG1 GNG11 WNT5A PDE6G PLCB2 ITPR2 AGO2 NFATC1 GNG2 TNRC6C AXIN2	down	*
GO_ENDOCYTIC_VESICLE_MEMBRANE	0.0000610	0.0012769	0.5573322	-0.3500899	-1.762532	124	RAB11FIP1 MCOLN1 HVCN1 WNT4 CAV1 MARCO CD9 LAMP1 SLC11A1 SCARF1 CD36 HBEGF RILP PICALM FZD4 WNT3A MSR1 NOSTRIN ATP6V0D2 EPS15 HLA-DQA1 ANXA3 TBC1D5 VAMP3 INPP5B SNAP23 RAB8B RAB31 RAC2 ATP6V0B RAPGEF1 RAB8A GRIA1 ATP6V0D1 UBB CD74 PIK3C3 ATP6V0C	down	**
GO_MITOTIC_SPINDLE_MIDZONE_ASSEMBLY	0.0018037	0.0197549	0.4550599	0.8761283	1.762497	5	RACGAP1 AURKB KIF23 MAP10	up	*
GO_GALACTOLIPID_BIOSYNTHETIC_PROCESS	0.0018037	0.0197549	0.4550599	0.8759850	1.762209	5	UGT8 GAL3ST1 FA2H	up	*
GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN	0.0000129	0.0003471	0.5933255	-0.3303172	-1.761775	183	HHEX SOWAHC ZC3H12C LYL1 LY86 LMO2 TMOD3 MYADM INPP5A NCF2 FUCA1 CD22 GGA2 ANXA1 PLA2G7 SH2B3 SLC7A7 GM2A MAP3K8 IFI30 PBX3 MS4A1 PPP3CA ADRB2 CD93 CD37 PPP3CC CDIP1 PLBD1 CLIC4 PER2 PDE1C HLA-DQA1 HCK MTPN TCTE3 PKIG LIMD1 KCTD12 CTSZ ATP6V0B SNX2 CD83 IRF8 PRKCE PXK PLCG2 SNX9 RHOQ IRF5 TCF4 SERPINB1 TEC CBFA2T3 CD81 BMP2K CCR6 SLC31A1 SPIB CXCR4 ALDH2 CD19 CTSC MCOLN2 IQGAP1 EVI5	down	***
REACTOME_EXTENSION_OF_TELOMERES	0.0030370	0.0293950	0.4317077	0.5003761	1.761749	38	RUVBL1 PRIM2 PIF1 RUVBL2 POLA2 POLD2 LIG1 DSCC1 BLM DNA2 FEN1 CHTF18 POLD1 RPA1 CHTF8 PRIM1 RTEL1 RFC5 NHP2 POT1 CTC1 POLD3 RFC3 RFC4 PCNA WRN	up	*
REACTOME_TELOMERE_MAINTENANCE	0.0030370	0.0293950	0.4317077	0.5003761	1.761749	38	RUVBL1 PRIM2 PIF1 RUVBL2 POLA2 POLD2 LIG1 DSCC1 BLM DNA2 FEN1 CHTF18 POLD1 RPA1 CHTF8 PRIM1 RTEL1 RFC5 NHP2 POT1 CTC1 POLD3 RFC3 RFC4 PCNA WRN	up	*
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_1	0.0034886	0.0328750	0.4317077	-0.4310540	-1.761345	41	KRT81 EREG FOSL1 TRIB1 HBEGF MALL SLC7A11 SHC4 ELK3 MAFF AREG PLK3 SPRY4 DUSP5 GEM EPHA2 LPAR6 REEP1 EGR1 DUSP6	down	*
GNF2_DDX5	0.0018732	0.0203206	0.4550599	-0.4017768	-1.761308	57	YPEL5 CCNL1 HNRNPDL SRSF5 BIRC2 BNIP2 PTPRC RSRC2 ACTR2 UFM1 RBM39 NXF1 HECA SF3B1 DDX5 RBM22 SRSF6 ADPGK PHF11 MBNL1 TRAPPC8 YTHDC1 CRBN SCAF11 STX16 SETD2 SCAF8 VPS13C	down	*
MODULE_280	0.0030370	0.0293950	0.4317077	0.5001458	1.760939	38	LTF MMP13 TF PTPRZ1 HS3ST1 CP SORD MMP1 ZNF117 PAH ZNF146 ADAM12 MMP7 ECEL1 POLR2I SUOX	up	*
REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	0.0004074	0.0062465	0.4984931	-0.3545253	-1.760926	104	RAMP3 GPR15 LHCGR ADCY9 ADCY4 RAMP2 PDE1B CALCRL ADCYAP1R1 RXFP1 PDE4C PDE2A GNGT2 ADRB1 GNG7 ADRB2 GPBAR1 PDE4D ARRB1 PTGIR GRK5 PDE8A PDE3B GNAI2 PTH1R ADCY2 PTGER4 PTGER2 GNAI1 GNG5 GPR84 GNB4 OR52B6 HTR6 ARRB2 ADORA2A PDE4A PDE8B OR1K1	down	**
SENESE_HDAC1_TARGETS_UP	0.0000000	0.0000009	0.7477397	-0.3026318	-1.760583	387	CXCL3 IL1A USP12 CD55 ROBO4 LPXN GPR65 BMP2 CD44 TMOD3 BACH1 LDB2 NEDD4L FOSL1 GPCPD1 GTF2I SLC39A8 RBM14 BCL2A1 OTUD4 TGFBR2 TRIB1 DNAJB14 GM2A CSGALNACT2 PTX3 SLC7A11 LCP1 SLAIN2 TOR1AIP1 JAM3 RB1 NFE2L2 SLC25A37 AKT3 SRGN TFRC MCL1 MYCT1 PTPN12 ITPRIP DUSP3 STX3 TPP1 LY96 ABCC4 CCL3 IRAK2 CCND2 PLEKHB2 PIK3C2A ELK3 UTP23 SLC6A6 IL7R BCLAF1 FKBP15 MAFF DEGS1 IL24 USP16 ACTR2 RAB6A CREM PHTF2 NSMAF PHACTR2 PNO1 SNAP23 RAB8B SERPINB8 SF3B1 CPEB4 ETS1 DESI2 CELF1 RAC2 ST6GALNAC4 ATP11A GLIPR1 PCGF5 IDS KBTBD8 COBLL1 ENTPD4 ATP13A3 CXCL5 OGFRL1 YWHAZ TNFRSF10B LETM2 MOB1A GPR3 RRN3 YTHDF3 PPTC7 AKIRIN2 STRN MTMR2 PDE12 DUSP5 NAB1 GALC MAP3K2 SOD2 KYNU GNA13 ADAM10 SERINC3 SNHG16 MBNL1 CCL20 GEM CEP170 TFPI CEBPD NLRP3 MEX3C PSME4 G3BP2 KPNA4 NFKBIA RASSF8 DOCK10 DUSP7 DNAJB9 DOCK4 NABP1 IQGAP1 SPOPL	down	***
GO_DNA_DOUBLE_STRAND_BREAK_PROCESSING	0.0044777	0.0394543	0.4070179	0.5971697	1.760450	20	BRCA1 WDR70 RBBP8 HELB BRIP1 BLM DNA2 SLX4 RAD50 UBE2V2	up	*
GO_HAPTOGLOBIN_HEMOGLOBIN_COMPLEX	0.0019012	0.0205803	0.4550599	0.8748812	1.759988	5	HP HBA1 HBA2 HBB	up	*
GO_AMINE_BINDING	0.0054414	0.0454450	0.4070179	-0.8874522	-1.759276	4	SLC6A4	down	*
GO_WOUND_HEALING	0.0000000	0.0000002	0.7749390	-0.2989037	-1.758979	436	AJAP1 CLEC1B EREG ACVRL1 IL1A HMOX1 PECAM1 CCM2L ADTRP GATA2 WFDC1 F2RL3 WNT4 P2RY1 THBD RCOR1 TRPC3 FYN MMRN1 CD44 CAV1 TBXA2R HMGCR FGF10 PRKAR1A CDC42 CD9 GAS6 SLC11A1 TGFBR2 HPS5 PEAR1 RHOA APOD CD36 ANXA1 MYOZ1 SH2B3 HBEGF FOXA2 ADAM17 ENTPD1 CLEC7A CSRP1 ITGA5 HSPB1 ANXA5 SLC7A11 GATA3 PPP3CA NFE2L2 CRK WNT3A SGCA PDGFA FOXC2 PTPN12 GPR4 ARRB1 DGKE PLAUR THBS1 MAFG MPL ITPK1 DOCK9 CDKN1A SELP AXL HPSE TLR4 CAPZA2 FCER1G ELK3 PLEK ADIPOR2 GNAQ UBASH3B PIK3R5 C4BPB MAFF IL24 AKIRIN1 VWF TGFB2 PROCR MTPN SRF NINJ1 PRCP KANK1 METAP1 IL6 NDNF NOTCH1 ETS1 DUOX1 ENPP4 IFRD1 PIK3R1 PABPC4 PRKCE PRKACA DOCK8 AP3B1 YWHAZ MCAM CD34 PLCG2 CD151 EHD2 SRSF6 PRKCG EPPK1 MYL12A DGKG STXBP3 TGFB1 EHD1 VAV3 ITGA9 TEC NLRP6 MIA3 CD81 CLASP2 GATA6 GNA13 MACF1 SMAD2 DOCK6 SYT11 FGF2 CPQ TFPI ARRB2 RAB5A CXCR4 ACTB ADORA2A JMJD1C MAFK EDN1 SCUBE1 PTEN PRKG1 P2RX1 NRG1 ZFPM2 EHD3 ANO6 PAPSS2 IRF2	down	***
GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_UP	0.0000140	0.0003722	0.5933255	-0.3323246	-1.758768	172	WEE1 CD52 SWAP70 USP12 CD55 LY86 PLEKHF2 S1PR1 BCL2A1 CD22 TXNIP ATP2B1 ENTPD1 MS4A1 CD37 EPB41L2 RHOB SYNPO FOXO1 YBX3 DENND3 CLIC4 DOCK9 LBH SS18L2 MBD2 HES1 IL24 BTG1 PHTF2 PIKFYVE JUN JUNB SNX2 CD83 IGKV3-20 CDK14 PLCG2 RHOQ PELI1 KLF2 CR1 GSAP VPREB3 PDLIM1 IRS2 GPR18 SPOCK2 CCR6 MOB3B TNFAIP8 CDC42EP3 SP100 ICAM3 CD19 LYST CNN2 BANK1 AFTPH ARHGEF18 EGR1 CDKN1B NUP88 PLEKHA2 TUBA1A CD69 CD79B PAX5 MTSS1 GABPB1	down	***
MODULE_2	0.0000001	0.0000046	0.7049757	-0.3087819	-1.758508	314	RBP4 SLPI STAC PECAM1 FABP4 CLEC3B EMP2 CYP4B1 LIPA RAMP2 CDH5 INSIG1 ENG LPL CD44 CAV1 MAL TGFBR3 EPB41L3 TGFBR2 RFTN1 HSPG2 APOD ANXA1 ASAH1 CSRP1 CYB5A GLS CAV2 NR4A1 SFRP1 ZEB1 SRGN TFRC CD37 CNN1 EPB41L2 RHOB CFD TBC1D9 MOAP1 SCP2 BIRC2 AOC3 CLDN5 PDE8A CCL3 LAPTM5 CDKN1A CADM1 PTPRC ATF3 CCND2 PER1 ADIPOR2 ACTG2 MYH11 HLA-DQA1 HES1 MAFF CRIM1 MAPRE2 VWF EMP3 LAMB2 CYB5R1 JUN LTBP2 JUNB ARHGEF10 RABGAP1 IFNGR1 PPP1R15A MFAP4 FSTL3 TNFRSF10B CD34 ACSL1 CD151 FOS MBP MSMO1 MME COL15A1 FCGRT RGS2 LTBP1 ETS2 MBNL1 SOD3 SYT11 GEM GPX3 TFPI RTN1 CXCR4 CDKN1C MEGF9 S100A4 TIMP3 MTUS1 MMD FGFR1 LDLR GRB10	down	***
GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION	0.0000178	0.0004568	0.5756103	-0.3423130	-1.758039	142	FFAR4 RAB11FIP1 ADTRP IL1B INSIG1 INPP5K BAG4 HMGCR GAS6 CD22 APOD CD36 ANXA1 MIR146A CARD16 ANXA5 PPP3CA RGCC SFRP1 SRGN TXN IL10 REST KLF7 DPH3 MIR24-2 FRMD4A SNX3 PKIG CARD8 DNAJA1 PTGER4 UBAC2 PPM1F CD34 PKIA SERPINB1 LRRC32 SYT11 NLRP3 SP100 PSMD9 ENY2 BANK1 PIM3 ACVR1C CHP1 C5AR2 KCNE1 FKBP1B	down	***
MIR3138	0.0016225	0.0182905	0.4550599	-0.3966803	-1.757351	60	SEMA6A SASH1 RAB3C ASAP1 ZNF365 GPA33 LIN7C DSE CRIM1 KREMEN1 C2orf69 PRPH2 CALM1 CCDC85A PKIA SBF2 UTP3 GSTM5 INO80 PDE4A GSPT1 SPOPL RAB2A	down	*
GO_REPLICATION_FORK_PROTECTION_COMPLEX	0.0044355	0.0391363	0.4070179	0.7620604	1.757128	8	CDC45 MCM10 TIMELESS GINS4 WDHD1 GINS2	up	*
REACTOME_S_PHASE	0.0000526	0.0011280	0.5573322	0.3944927	1.757011	149	CDC45 PRIM2 GINS1 CDK4 POLE CDC6 TFDP2 MCM4 MCM2 CDC25A ORC1 MCM8 GINS4 CDT1 POLA2 POLD2 MCM7 CDCA5 MCM3 LIG1 ORC6 PSMD4 AKT2 MNAT1 SKP2 CKS1B ANAPC5 POLE2 E2F1 PSMB5 DNA2 ANAPC7 FEN1 PSMC4 CCNE1 CDC23 PSMA5 PSME2 ESCO2 GINS2 FZR1 LIN37 ANAPC1 POLD1 PSMD2 PSMB3 RPA1 MCM6 MCM5 GINS3 PSMB4 CCNA2 PRIM1 ANAPC2 RFC5	up	**
REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	0.0023966	0.0246022	0.4317077	-0.3889177	-1.756656	65	EREG CAV1 HBEGF GNGT2 HSPB1 CAV2 GNG7 AKT3 EPGN GNAI2 SRF AREG PIK3R1 CREB1 FOS CALM1 FOXO3 STRN GNAI1 GNG5 GNB4 HSP90AA1 ZDHHC21 SPHK1 CDKN1B MAPK1 GNG11	down	*
GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_UP	0.0043914	0.0388672	0.4070179	-0.4646969	-1.756519	33	U2AF1 CHMP1B ANXA5 ATP6V1B2 HLA-DQA1 MAFF CREM STAT4 CD83 FXYD6 SDAD1 ZBTB44 VPS13D	down	*
GO_LIGASE_ACTIVITY	0.0004117	0.0062982	0.4984931	0.4098955	1.756253	108	CPS1 UCHL1 SLC27A2 GMPS AACS LIG3 AARS2 TTLL4 BTRC PCCB SAE1 LARS2 MCCC2 TARS2 LIG1 SARS2 ASS1 ACSF2 MDM2 CAD HARS2 TTLL9 ACSBG2 LIPT2 RTCB PARS2 GSS AARSD1 ASNS ACSL6 NADSYN1 YARS2 PFAS IARS2 TTLL3 TTLL6 FARSA ACSF3 HLCS FARSB EARS2 MTHFD1 PAICS TTLL5 ACSL5 ACSBG1 ACSM3 SLC27A5 MARS2 NAE1 PC MCCC1 CARNS1 CTPS1 SLC27A1 DARS2 GCLC SUCLG1 NARS2 MTHFS GART TTLL1 ACSS2 UBA2 ACSS3	up	**
GO_CILIUM	0.0000000	0.0000011	0.7337620	0.3574710	1.756185	440	PKHD1 STRC KLC3 CNGA1 CEP89 DNAH2 PMFBP1 RPGRIP1L PROM1 CENPF IQCE CIB2 MKS1 SORD FANK1 IFT122 CATSPERB DAW1 SPAG17 TTC26 IFT27 DNAH3 GUCA1B KIF27 DNAH14 AK8 DNAI1 NPFFR1 CEP250 RSPH1 TTLL4 ARMC4 BBS1 SPAG16 TSGA10 KIF3B FBF1 AURKA IQCD ODF2 IFT43 HAVCR1 POC1A HYDIN AGBL4 WDR78 TEKT2 KISS1R CCDC114 PKM DCDC2 PEX6 WDR66 WDR60 NME5 DNAH8 SLC9A3R1 PROM2 IFT172 GAS8 KIF3C CBY1 CNGB1 DNAH11 RABEP2 C2CD3 TRPV4 DLG5 TULP3 CCDC40 DRC1 LRRC6 IQCB1 CROCC DNAH6 KIF5A CENPJ MERTK TTLL9 KIF19 SPAG6 TCTN2 KIF2A KIF7 SSX2IP DYNLL2 POC1B SMO LCA5 NAPEPLD AK7 DNAH5 LRRC56 TCTE1 ABCA4 TMEM231 IFT52 CATSPERG ELMOD3 SPEF1 EVC2 BBS5 CATSPER3 NPHP1 TUBG1 DNAH7 EFCAB2 MNS1 CCDC151 IQCG SPTBN5 TMEM237 CNGA4 TEKT3 SPA17 CEP128 TRAF3IP1 CLTB DNAJB13 EFCAB7 AGBL2 IQUB ROPN1B WDR34 TTLL3 EFHC1 TCTN1 CATSPER2 RPGRIP1 ODF2L FAM183A DNAI2 RAB15 ANKS3 WDR35 DYNC2H1 NEK4 FAM161A TBC1D30 TTLL6 RSPH4A UNC119B RAB34 SPAG4 TMEM17 CATSPER1 B9D1 ALMS1 ICK CEP164 CCDC181 CLUAP1 NUBP2 DNAH1 MARK4 ENKUR TBC1D32 TACR1 ADCY6 ANKMY2 ADAM15 PDZD7 DHRS3 UBXN10 ANKS6 TSSK4	up	***
SHIN_B_CELL_LYMPHOMA_CLUSTER_3	0.0052379	0.0442645	0.4070179	-0.4847477	-1.755930	26	HHEX FGR ZEB2 NFKB1 CADM1 ID2 TNFSF13 TGFB1 CD86 IL18 CCND3	down	*
GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_GROWTH	0.0003740	0.0058549	0.4984931	-0.3658531	-1.755825	91	SLC6A4 TNR RBP4 SEMA6B SEMA3G SEMA6A TGFBR2 SEMA6D WWC2 MYOZ1 SEMA3B ADRB1 ADRB2 SFRP1 WNT3A TRIM46 SOCS2 CDKN1A TBX5 MIR17HG IFRD1 RTN4R SAV1 MEIS1 RGS2 SEMA4A RTN4 PTCH1 ULK2 STK4 PTEN	down	**
SCHLOSSER_SERUM_RESPONSE_DN	0.0000000	0.0000000	0.8870750	-0.2887289	-1.755442	615	HCRTR1 KMO SC5D SECISBP2L CD55 FCN3 MNDA CYP27A1 CAT SLC16A4 PTP4A2 INSIG1 RUNDC3B COQ2 BACH1 GTF2E2 MYD88 SLC39A8 IDI1 CIR1 HMGCR DYRK1A PRKAR1A MEF2A ELMO1 MANBA CD9 HPS5 RCHY1 ZEB2 EDEM1 KCNAB1 TRA2B ADAM17 RAP1A EIF1 BZW1 EIF5 SERINC1 REV3L TOR1AIP1 PPP3CA SIRPA RB1 TMEM123 NFE2L2 ZFYVE16 ITSN2 TCAP GPM6A PPP3CC ADARB1 HMGN1 SCP2 SRSF5 HNRNPA3 SDCBP CASP1 KLF4 FAM76A LEPROTL1 ZFAND5 MAP1LC3B TMED5 MED6 CLIC4 LY96 SEC24B PDE8A PTPRC DUSP11 EPS15 EVI2A MBD2 DSTN PAFAH1B1 BCLAF1 SMNDC1 TP53BP2 CALM2 CRIM1 ACTR2 TDRD7 HEXB SACM1L NCKAP1L SERTAD2 PDK4 SLC25A3 RYBP CDC40 GABARAPL2 PGD DCTN6 RBM34 NEK7 PIKFYVE PPP6C SF3B1 PSMA1 CUL4A USO1 MTMR9 TMEM251 WTAP SNX2 SDHD HSPA13 DDX5 GMFG MORC3 TPP2 RNF24 DLEU2 YWHAZ NDST1 SNRK WDR7 CACYBP CD164 PTP4A1 PSMD12 MSMO1 ICAM2 MYL12A AZIN1 STXBP3 EPB42 HNRNPA2B1 NIPA2 LSM6 PHF3 NDUFA5 DCK PDS5B UTP3 PPIG TOB1 STX12 DECR1 NPTN CLASP2 CRY1 MAGOH ACYP2 PHF2 PGGT1B ADAM10 SERINC3 ETS2 MBNL1 ATAD2B CCNH GTF2B RBL2 ARAP2 LDLRAD4 YAF2 CCDC69 CGRRF1 NBN MGAT2 NT5C2 SEC63 RTN4 RAB5A USPL1 SEC61B DHRS12 ARIH1 TBC1D1 SP100 MEGF9 BCAM CREBBP GLUL COPS8 ACADM PAK2 FDFT1 MMD LDLR PSMD6 CREG1 NUP160 EID1 RSU1 ATF4 BMI1 EVI5 PMAIP1 LYZ SLC35A1 DMXL2 SNRPG HAT1 YTHDC1 ABI1 PSIP1 KALRN PLAG1 UBR2 CLIP1 ATP11B HIPK1 ATF2 ZNF259P1 SH3GLB1 RB1CC1 FAM8A1 CBR4 EFS PPWD1 PPIP5K2 SRSF11 IFIT5 PPFIA1 LAMTOR5 UBE3A KIDINS220 AKAP12 CAPZA1 CDK7 RAD21 PCMT1 NMI DLD FANCC EP300 ATP8A1 RCBTB2 SMARCA5 POLR2B	down	***
GO_GDP_BINDING	0.0013524	0.0160660	0.4550599	-0.3956919	-1.755381	61	ARL8B RHOA RRAGC RAP1A RAB14 RHOB RAB12 RIT1 RASL12 RAB8B RAB31 RAB8A RALB RRAS GNAI1 DYNC1LI1 GEM RAB5A	down	*
GO_HARD_PALATE_DEVELOPMENT	0.0028625	0.0280699	0.4317077	0.8330175	1.755303	6	FOXE1 DLG1 SOX11	up	*
CHYLA_CBFA2T3_TARGETS_UP	0.0000002	0.0000076	0.6901325	-0.3091856	-1.755114	311	SLPI TEK OLR1 ENDOU CCM2L HVCN1 TMEM150B FBP1 F2RL3 RAB44 CLEC12A GPR65 AATK ESAM PLEKHA1 TBXA2R CLEC10A ALAS1 NCF2 TET2 IGSF6 PDE2A SIGLEC6 MCTP1 SGMS2 C1orf21 ANXA5 ABCG1 HDC LCP1 CD93 SPTBN1 TFEC ARHGEF2 SPI1 ARL11 MYCT1 TMEM38B ATP10A RHOB EVI2B FABP5 CSRNP1 SPNS3 MEFV NOSTRIN PPM1K CASP1 GCHFR AFAP1L1 DRAM1 SOCS2 ITIH5 GMPR LAPTM5 DOCK9 HPSE CXXC4 CCND2 TM6SF1 ALOX5AP GCA DSTN UBASH3B HLA-DQA1 ANXA3 BACE1 ARHGDIB FLT1 TMOD1 KLRB1 CABLES1 CD48 VAT1 RAB31 HK3 TREM1 ELOVL7 GMFG PTGER2 GPRC5A RALB CST7 CELF2 CD34 PLCG2 RHOQ	down	***
GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_DN	0.0000553	0.0011749	0.5573322	0.3940355	1.754975	149	COL17A1 TRIP13 KCNMB2 GRIK2 FOXM1 IGSF9 NXPH4 MCM10 SLC9A2 PBK BRCA1 GINS1 SLC27A2 FCER2 PAK6 E2F3 TRIB3 CHRDL2 KIAA0895 SMARCC1 ZNF572 KNTC1 KIF2C PFN2 CAPN12 MST1R MTG1 PON1 INCENP EFCAB6 POLR3K UNG TNNI2 PSAT1 POLR1C AK7 ABCA4 NRIP2 LMNB2 HMGN3 ATAD5 CACNG8 NOC4L ADCK1 LRRC46 ALG8 SPAG4 AGMAT SCRG1 SNX7 MAP3K9 PPFIA3 FBN2 ARHGAP11A AGBL5 HOXB2 MXD3 TIMM44 APEX1 NSUN7 E2F7 TRUB2 MRAP	up	**
PID_E2F_PATHWAY	0.0020911	0.0222043	0.4317077	0.4389032	1.754865	67	BRCA1 CDC6 E2F3 TFDP2 RBBP8 TYMS CDC25A MYBL2 ORC1 RANBP1 WASF1 E2F2 RRM2 TRRAP MCM3 TOPBP1 XRCC1 CDKN2C CBX5 CDK1 E2F1 CCNE1 TK1 CASP7 HDAC1	up	*
REACTOME_NEUTROPHIL_DEGRANULATION	0.0000000	0.0000006	0.7477397	-0.3018186	-1.754852	397	SIRPB1 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 MNDA LTA4H CAT RAB44 CLEC12A PTPRB OSCAR CD44 CHIT1 CYB5R3 PAFAH1B2 C5AR1 YPEL5 MANBA VAPA FUCA1 LAMP1 SLC11A1 LILRB3 FGR RHOA CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ASAH1 RAP1A GM2A ANPEP PTX3 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 RAB14 CD58 CST3 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL HPSE ARHGAP9 CD53 FCER1G GCA DEGS1 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP CTSS PSEN1 SNAP23 VAT1 RAB31 HK3 CTSZ TYROBP HSPA1B ATP11A RHOG ENPP4 GLIPR1 GMFG SERPINB6 CAP1 PSMD12 ALDH3B1 BIN2 CR1 MME TIMP2 SIGLEC14 DOK3 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 LGALS3 ORM2 BRI3 PLEKHO2 ADAM10 IST1 COMMD9 UNC13D HSP90AA1 HSPA8 METTL7A NHLRC3 SIGLEC9 CTSC ARPC5 SNAP29 P2RX1 PSMD6 IQGAP1 CREG1 CNN2 ANO6 LYZ CYBA ATP6V0A1 CTSH TMEM30A ATP11B MAPK1 ITGAL FTL S100A8 RAB37 FPR1	down	***
GO_SPINDLE_POLE	0.0000964	0.0018722	0.5384341	0.3950392	1.754695	145	DDX11 CEP89 NEK2 CCNB1 CENPF ASPM PLK1 AURKB CDC6 TPX2 PRC1 DYNC1I1 SPDL1 WDR62 BOD1 KNTC1 AUNIP FBF1 MAP10 AURKA ODF2 MAD1L1 POC1A WDR73 KIF11 GPSM2 WDR60 TOPBP1 MAD2L1 CKAP2L PSRC1 KNSTRN KIF2A SPAG5 POC1B KLHL22 CEP63 TUBG1 DLGAP5 TACC3 PKP4 KIF20B CEP128 CKAP5 CDC20 AAAS EFHC1 CDK5RAP2 CKAP2 FAM161A KATNB1 NUP62 CEP85 ALMS1 TUBGCP4 NUBP2	up	**
GO_REGULATION_OF_MEMBRANE_REPOLARIZATION_DURING_VENTRICULAR_CARDIAC_MUSCLE_CELL_ACTION_POTENTIAL	0.0020312	0.0216984	0.4317077	0.8722094	1.754614	5	NOS1AP DLG1 KCNE3 RNF207	up	*
chr1q32	0.0001245	0.0023184	0.5188481	0.3966252	1.754420	140	LEMD1 MROH3P MYBPH LAD1 ASCL5 NEK2 PPFIA4 FLVCR1 UBE2T TNNI1 MIR205HG PKP1 PLEKHA6 SNX25P1 KIF14 CR1L KLHDC8A DTL TMEM81 IKBKE TNNT2 HHAT VASH2 SMYD2 RNU6-418P SYT2 LINC00862 IPO9 SLC45A3 LRRN2 SERTAD4 TRAF5 SNRPE IRF6 INTS7 NFASC PCAT6	up	**
GO_ACTIVIN_RECEPTOR_BINDING	0.0059476	0.0485953	0.4070179	-0.8849726	-1.754361	4	SMAD6 NODAL INHBA MAGI2	down	*
GCM_DPF2	0.0043454	0.0385266	0.4070179	0.5711285	1.754347	23	HMGA2 TP53BP1 FUT2 VPS72 DGCR6 COX10 AAMP TTC1 BCAT2 PRKAG1 BNIP1 SDHC MPP2 RFX5 SMARCD1 DRG2 ADCYAP1	up	*
GSE30962_ACUTE_VS_CHRONIC_LCMV_PRIMARY_INF_CD8_TCELL_DN	0.0000149	0.0003935	0.5933255	0.3839594	1.753930	185	TRIP13 HELLS FAM81A NEK2 MPP6 DDIT4 GMPS CDC6 TFDP2 CCNB2 FIGNL1 UHRF1 SPATS2 UMPS GLDC XRCC2 DTL TAMM41 RANBP1 CXCL10 MELK EXO1 PAQR4 BUB1 SMYD2 HOOK1 RAD54L FANCD2 CCDC58 CHEK1 MAD2L1 RAD18 INPP4B BLM FLNB KNSTRN NCAPG2 C12orf75 PLOD2 SLC25A13 PSAT1 FEN1 SPAG5 DIAPH3 RTP4 CENPP NRGN ST14 AKR1E2 KIF22 HMGN3 C9orf152 GAS2 CEP128 ATAD5 CENPK	up	***
GO_SULFATE_TRANSPORT	0.0032010	0.0306611	0.4317077	0.6634320	1.753892	13	SLC26A4 RACGAP1 SLC26A8 SLC25A10 SLC26A2 SLC13A4 SLC26A1	up	*
GO_PYRIMIDINE_RIBONUCLEOTIDE_METABOLIC_PROCESS	0.0048244	0.0415946	0.4070179	0.5948911	1.753733	20	UMPS NME1 NME9 NME5 CAD UCK2 UCKL1 UPP2 DHODH NME4 NME7	up	*
REACTOME_MITOTIC_G1_PHASE_AND_G1_S_TRANSITION	0.0001125	0.0021288	0.5384341	0.3964844	1.753436	141	CDC45 MCM10 CCNB1 PRIM2 CDK4 POLE CDC6 E2F3 TFDP2 MCM4 MCM2 TYMS CDC25A MYBL2 ORC1 MCM8 CDT1 TOP2A POLA2 MCM7 E2F2 RRM2 MCM3 ORC6 PSMD4 AKT2 MNAT1 SKP2 CKS1B CDKN2C CDK1 POLE2 GMNN E2F1 PSMB5 PSMC4 CCNE1 PSMA5 PSME2 TK1 HDAC1 LIN37 PSMD2 CDC7 PSMB3 RPA1 MCM6 MCM5	up	**
GSE45365_NK_CELL_VS_CD11B_DC_DN	0.0000154	0.0004038	0.5756103	-0.3286499	-1.752883	183	SIRPB1 CD300LF OLR1 IL1B CD44 FOSL1 SLC15A3 STX11 IL1RN PILRA EIF4A1 HBEGF PPP1R15B CLEC7A BTG2 PTX3 STOM SPI1 TUBB6 TIPARP PTPN12 CSRNP1 STAT5A MEFV MPEG1 VASP ADAMTS9 PLBD1 CLIC4 EPGN CXCL2 CCL4 DUSP1 MAFF CD300LB ARHGDIB NRROS RNF149 IL6 RAB31 TREM1 JUNB JAK1 OSM GPRC5A SLC3A2 FOS TGFB1 FPR2 DUSP5 CD86 PIM1 PDE4B ETS2 IST1 ICAM1 SELPLG ADAMTS4 IER5 RND1 NFKBIA ZFAND2A JDP2 EGR1 CSF2RB SERPINE1 CLEC4E S100A8 ZFP36	down	***
GNF2_PTPRC	0.0015748	0.0179019	0.4550599	-0.4073974	-1.752825	54	GPR65 GIMAP6 TXNIP FLI1 OSTF1 PTPRC CD53 HECA CD48 RAC2 JAK1 DDX5 SNRK KLF2 BIN2 GSAP PHF11 CLEC2B MBNL1 ICAM3 CYTH1	down	*
GO_NEGATIVE_REGULATION_OF_PEPTIDE_SECRETION	0.0002847	0.0046701	0.4984931	-0.3582763	-1.752413	98	FFAR4 RAB11FIP1 ADTRP IL1B HMGCR GAS6 CD22 ANXA1 MIR146A CARD16 ANXA5 PPP3CA RGCC SFRP1 SRGN IL10 REST KLF7 DPH3 MIR24-2 FRMD4A CARD8 PTGER4 CD34 CD74 SERPINB1 LRRC32 SYT11 NLRP3 PSMD9 ENY2 BANK1 PIM3 KALRN ACVR1C C5AR2 FKBP1B	down	**
GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP	0.0000200	0.0005024	0.5756103	-0.3294726	-1.752324	184	ZC3H12C LYL1 LY86 INPP5A DYRK1A BCL2A1 NCF2 WBP4 CYP4A11 CD22 GGA2 SH2B3 UBL3 LATS2 PPP1R15B MS4A1 SRGN UBE2D3 MCL1 RAB14 EPB41L2 MPEG1 PLBD1 FAM49B SELL PLEKHB2 SMNDC1 HLA-DQA1 HCK SACM1L MTPN PKIG ASNSD1 LIMD1 KCTD12 ETS1 RCAN1 SNX2 SKIL EEA1 CD83 RASSF2 PLCG2 SNX9 RHOQ CD74 IRF5 TCF4 AP1G1 SERPINB1 VAMP4 TEC GNA13 ADAM10 SERINC3 IST1 CCR6 ICAM1 SPIB ARIH1 CD19 CTSC DNAJB9 EID1 EVI5 DNAJA2 EIF4G2 CTSH CNR2	down	***
GO_MEIOTIC_CHROMOSOME_SEGREGATION	0.0016835	0.0187544	0.4550599	0.4552161	1.752210	56	TRIP13 BUB1B TTK PLK1 NUF2 PTTG1 ESPL1 STAG3 BUB1 TOP2A EME1 REC8 SYCP2 FANCD2 HORMAD1 EME2 BRIP1 SUN1 CCNE1 SLX4 ANKRD31 MEI1 FANCM	up	*
GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	0.0000183	0.0004671	0.5756103	-0.3300544	-1.752209	174	GFOD1 S1PR1 OTUD4 IL23A IER2 ANXA1 SH2B3 RRAGC UBL3 NR4A1 PDGFA CSRNP1 MTMR6 LEPROTL1 TMBIM1 DUSP11 PLEKHB2 SMAD7 PLEK RPF1 DSE SLC25A32 IL7R UBASH3B MIR17HG MAPRE2 MYLIP CREM HCFC2 NXF1 NOTCH1 KCTD12 OSTM1 PTGER4 CD83 REL RASSF2 CEBPZ ZNF350 ADNP2 PTP4A1 NIPA2 VAV3 CD6 MAP3K2 TAGAP TMEM70 GPR18 KTI12 SDCBP2-AS1 NBN CDC42EP3 ARIH1 NUP98 EPB41L4A TTC19 MTUS1	down	***
BIOCARTA_G2_PATHWAY	0.0043454	0.0385266	0.4070179	0.5704295	1.752200	23	CHEK2 CCNB1 BRCA1 PLK1 CDC25A ATR PRKDC CDC25C CHEK1 MDM2 CDK1	up	*
ACEVEDO_LIVER_CANCER_WITH_H3K27ME3_DN	0.0001155	0.0021777	0.5384341	0.4015726	1.752066	126	RHPN2 ANKRD36C GRIK2 PCDHGA10 CPLX2 ZFHX4 PCDHGA9 COL27A1 TSHZ2 PCDHGA7 CHST4 PHGDH PCDHGA6 ANLN PCDHGB3 PCDHGB6 PCDHGB4 COCH APOL2 ANKRD36B KIAA0895 PCDHGA11 PCDHGA8 KIF15 PCDHGC5 PCDHGC4 PCDHGB7	up	**
REACTOME_AURKA_ACTIVATION_BY_TPX2	0.0024029	0.0246575	0.4317077	0.4407263	1.751791	65	CEP72 NEK2 CEP70 PLK1 TPX2 DCTN2 HAUS5 CEP250 HMMR AURKA ODF2 SFI1 CDK1 CENPJ FGFR1OP CEP63 CEP192 TUBG1 NINL CKAP5 CDK5RAP2 HAUS6 HAUS4 CEP152 ALMS1 CEP164 CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT	up	*
GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN	0.0000063	0.0001886	0.6105269	-0.3319990	-1.751689	171	SASH1 HVCN1 PLEKHF2 RGS9 CALCRL SUSD2 PRPF38A NR3C1 USP47 NUMB EIF4A1 ADAM17 LATS2 SERINC1 KLF6 DACH1 FAM122A CRK AKT3 ZFYVE16 BTG3 PLAUR VASP PDE8A GPR85 ATF3 LBH UBE2B WDR48 NUS1 RUFY3 PIAS1 SACM1L UFM1 CD80 DDHD1 PPP6C NXF1 GABPA ACKR3 PI4K2B RAB8A HSD17B12 CST7 PELI1 MAPK8 SAV1 IFNAR1 STX12 HACE1 LDLRAD4 ARL14EP SRSF10 NFKBIA C21orf91 MT2A BMI1 RABGEF1 PIM3 UBXN8 TBPL1 ATF2 MSANTD3 ATP1B1 SRSF11 MFSD1 UBE3A ALKBH3 ADHFE1 IRF1	down	***
GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP	0.0000320	0.0007416	0.5573322	-0.3299787	-1.751472	180	HHEX ZC3H12C SNX10 LYL1 HSD17B11 LMO2 TMOD3 MYADM GGA2 PTS UBL3 SLC7A7 SBDS ENTPD1 IFI30 PBX3 MS4A1 RB1 TMEM123 NDEL1 SPI1 MCL1 RAB14 TUBB6 TIPARP ARRB1 MPEG1 CASP1 KLF4 PLBD1 PDE8A SELL EPS15 HLA-DQA1 HCK MTPN PKIG ASNSD1 PHTF2 CTSS LIMD1 GABPA CTSZ SNX2 STX7 PRKCE RHOQ CD74 IRF5 TCF4 TEC WBP2 SERINC3 PPID IL18 SPIB VPS4B CD19 DNAJB9 MCOLN2 IQGAP1 RNF13 KLC1 CTSH ZNF106 DRAM2 LMO7 CD79B GPR137B FCRLA ITGA6 RNGTT WDFY2	down	***
GO_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.0000152	0.0004007	0.5933255	-0.3305807	-1.751407	173	RBP4 CCM2L TBX3 BMP2 SIK1 ENG S1PR1 PRKAR1A MEF2A CDC42 TGFBR3 TGFBR2 HEG1 JPH2 TBX2 LMNA WNT3A HNRNPU TCAP FOXC2 TNNC1 ADAMTS9 ID2 MIR24-2 SMAD7 ZMPSTE24 TBX5 MYH11 MIR17HG TGFB2 SRF RBPJ SLC8A1 NOTCH1 ADRA1A CREB1 NDUFV2 CACYBP SAV1 TGFB1 MIR23A PIM1 MEIS1 MYOCD GATA6 ACTN2 RGS2 RXRA FGF2 PDLIM5 FKBP1A ARRB2 EDN1 PTEN FGFR1 MIR548C NRG1 ZFPM2 SMAD4 GREM1 GJC1 MAPK1 MYH10 ITGB1 NOG EFNB2 CALR WNT5A PLN	down	***
GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN	0.0000127	0.0003428	0.5933255	-0.3290673	-1.751345	177	WEE1 RAB11FIP1 SNX10 CLDND1 TGFBR3 RFTN1 ANXA1 ATP2B1 UBL3 TTYH2 KLF6 STOM GATA3 SRGN CD58 EVI2B AHNAK LIMS1 COTL1 EPS15 RNF139 SLC6A6 GNAI2 DEGS1 GLB1 PHTF2 KLRB1 PHACTR2 IL2RB AQP3 RAPGEF1 GLIPR1 GPR183 TAGLN2 TIGIT GPRIN3 CD74 AKIRIN2 PEA15 DUSP5 ATXN1 LGALS3 CCR6 SLC35D2 CDC42EP3 EPHA4 ARHGAP18 ACTB S100A4 MCOLN2 KIF1B RORA NABP1 IQGAP1 EHD4 RSU1 MIS18BP1 PMAIP1 PIEZO1 HERPUD1 SPPL2A SH3BGRL3 ENDOD1 ITGB1 HLA-DRB1 RNF214 ATP2B4 NCOA7 RNF19B MYO1F MYO5A CBLL1 ADAM19 PLXNC1 TNFRSF1B GZMK IL10RA TANK EZR ZC2HC1A TMEM64 IQGAP2	down	***
MODULE_303	0.0036924	0.0341556	0.4317077	0.5455388	1.751107	27	BUB1B NEK2 TTK CDK4 PLK1 BUB1 CHEK1 CDK1 ULK1 CDK3 MAPK10 CDC7 CSNK1G2 ECHS1 CDK5	up	*
GSE1460_DP_VS_CD4_THYMOCYTE_DN	0.0000127	0.0003428	0.5933255	-0.3289844	-1.750904	177	EPAS1 ACP5 LPIN2 CD55 GPR65 SIK1 CD44 LY86 PLEKHA1 S1PR1 BCL2A1 FUCA1 SCN5A PBOV1 SLC7A7 PCYOX1 ASAH1 TMEM204 KLF10 GNG7 SPTBN1 PDE4D ZNF365 PDGFA KDSR ADARB1 ARRB1 CASP1 COTL1 SELL CCND2 CD53 ELK3 SMAD7 TBC1D4 HGSNAT EMP3 ARL6IP5 IL2RB RAB8B CCR7 KLF2 CPA3 EHD1 PDE4B RNF2 JUND BMP2K CPQ WDR1 IQSEC1 TPT1 SP100 ULK2 ABCA8 GPR171 CAMSAP2 THEMIS2 GRB10 IL16 MAN1C1	down	***
GO_POSITIVE_REGULATION_OF_VASCULATURE_DEVELOPMENT	0.0000184	0.0004686	0.5756103	-0.3307665	-1.750590	169	ANGPT4 TMEM100 ACVRL1 IL1A SASH1 HMOX1 TEK GATA2 IL1B TIE1 RAPGEF2 BMPER RAMP2 CDH5 ENG TBXA2R C5AR1 MIR27B TGFBR2 ANXA1 MIR146A RAP1A ITGA5 HSPB1 NFE2L2 GRN AKT3 FOXC2 NODAL RHOB IL10 TNFSF12 KLF4 THBS1 ITGAX PIK3C2A PTGIS ANXA3 BTG1 FLT1 NOTCH1 ETS1 JAK1 RHOJ	down	***
MIR4645_3P	0.0004282	0.0064921	0.4984931	-0.3645527	-1.750107	90	CPEB2 TTC7B YPEL5 MEF2A SYS1 RHOA LATS2 RAP1A AKT3 CYBRD1 ADO MYRIP ELK3 RBM44 CALM2 MAGI2 PDCD6IP GABPA ZFP91 DESI2 DUSP8 MBNL2 AP3B1 HINT3 MACF1 ADAM10 ABL2 LRP12 RAPGEF3 SAMSN1 NRG1 PUM1 CSF2RB TSTD3 SLC38A2 AQR	down	**
MODULE_552	0.0029564	0.0288286	0.4317077	0.8305510	1.750106	6	CENPA MYBL2 EZH2 CBX1	up	*
GO_CATALYTIC_ACTIVITY_ACTING_ON_A_TRNA	0.0007131	0.0097811	0.4772708	0.4183284	1.750062	91	METTL1 AARS2 QTRT1 LARS2 NSUN2 TRPT1 TARS2 SARS2 TRMT61B TRIT1 HARS2 DTD1 TYW1 PARS2 PUS1 AARSD1 TSEN54 ELAC2 YARS2 IARS2 DUS1L POP7 METTL2B NSUN6 DUS4L RPP38 DUS2 FARSA WDR4 FARSB TARBP1 EARS2 POP4 CDKAL1 DTD2	up	**
MEISSNER_BRAIN_HCP_WITH_H3K27ME3	0.0001450	0.0026241	0.5188481	0.3962361	1.749958	138	HMGA2 SIM2 MNX1 SLC5A5 HOXD8 IGF2BP3 HOXB6 NPAS1 PKP1 FOXE1 IRX6 SIX1 HOXB7 IGFBPL1 INSRR SPAG16 CBLC CYP24A1 THBS4 RSPO4 B3GNT3 PROM2 SPINT1 HOXB5 TRPV4 KRT18 DMGDH PRRX2 SPAG6 SLC44A3 WDR86 IRF6 TBX1 CRLF1 ALX4 SALL4 GRIN3B ECEL1 KRT19 TMEM30B MARCKSL1 NAGS HNF1B CHMP4C WNT10B ADAMTS14 CHRNA3 IL12RB2 CDCP1	up	**
GTAAGAT_MIR200A	0.0039994	0.0361976	0.4070179	-0.4322972	-1.749871	39	DLC1 QKI DYRK1A UBR3 NR4A1 KLF9 PAFAH1B1 SGK1 IPO7 SP3 PCGF5 SRSF6 SP100 PURB TRMT1L KMT2E UBE3A HMGB1 RAB1A	down	*
MIR4651	0.0001022	0.0019718	0.5384341	0.3885068	1.749860	159	ONECUT2 ENTPD2 MEX3A PCDHGA10 CPLX2 FAM177B PCDHGA9 PCDHGA5 PCDHGA7 ASIC1 PCDHGA1 PCDHGB3 RGS6 GRIN2A VSTM2L EFNA5 PCDHGA11 PCDHGA8 C9orf116 PCDHGA12 MAP3K13 PCDHGB7 PCDHGA3 WDR66 EGFR SLC9A3R1 MSI1 CYP2W1 PML TTYH3 MEOX1 SLC45A3 TTBK1 IGFBP5 SRCIN1 NAV2 ZNF584 KSR2 PCDHGA2 CCL21 NPTXR DVL3 SYNGAP1 ZBTB7B EPN1 MDGA1 RAI1 KIF21B BSN SSH3 GNG4 TFAP4 TBC1D16 MMP24 LHPP PATZ1	up	**
MIR152_3P	0.0000002	0.0000084	0.6901325	-0.3111567	-1.749794	297	EPAS1 PNPLA6 FOXF1 TEK OSBPL11 SECISBP2L LIPA SIK1 DDX6 QKI GPCPD1 ZCCHC2 MTMR10 S1PR1 ARL8B OTUD4 EOGT TXNIP HECW2 ADAM17 ITGA5 KLF6 ITSN2 UBE2D3 TFRC RAB14 GPM6A AGO4 NRARP KLF4 LEPROTL1 ROCK1 MAFG EPM2A MPL ITPK1 CADM1 EPS15 DUSP1 PIK3C2A CUL5 PEAK1 PRICKLE2 PDE1C TANC1 NCOA1 TGFB2 SNN TMEM9B ADCY2 VPS37A PHACTR2 MTMR14 MITF BMP3 CNTN4 ATP11A MTMR9 ZNF804A FAM43A RC3H1 HOMER1 TRAK2 GPRC5A CASZ1 WDFY4 AGFG1 ITGA9 PHF3 KIAA0232 BAZ2B SBF2 SKIDA1 MMP15 ATXN1 NPTN ADAMTS15 LTBP1 PLAA CLCN6 ADAM10 DOCK6 MIER1 INO80 EPN2 RTN4 CYB5R4 MAP3K4 ING2 RASSF8 RNF38 MMD CAMSAP2 CNTNAP3B LDLR FEZ2 USP48 ZFYVE26 STARD13 CDC14A CFL2 CDKN1B TGOLN2 EYA3 NOG EFNB2 YWHAB SRSF11 SPTY2D1 WDR47 ARHGEF12 ATP8A1 ATP2B4	down	***
chr2p22	0.0040914	0.0367851	0.4070179	-0.4167086	-1.749419	48	GPATCH11 NLRC4 HEATR5B SRSF7 NDUFAF7 PRKD3 CRIM1 SLC8A1 ATL2 CEBPZ BIRC6-AS1 STRN LTBP1 SLC8A1-AS1 CDC42EP3 FEZ2 RNU6-577P	down	*
GO_T_CELL_MIGRATION	0.0030509	0.0294997	0.4317077	-0.4098626	-1.749324	51	CXCL16 GPR15 SPN S1PR1 RHOA APOD ADAM17 CRK CCL3 XCL2 OXSR1 LRCH1 GPR183 DOCK8 ADAM10 CCL20 CCR6 ICAM1	down	*
GO_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	0.0000170	0.0004404	0.5756103	-0.3350853	-1.749199	158	FOXF1 HMOX1 SCIMP GATA2 IL1B CLEC12B PRAM1 CD1C LAMP1 IL23A FGR DNASE1L3 CLCF1 SERPINB9 GATA3 IL18R1 TRAF6 CRK CRTAM TFRC IL10 PTAFR FAM49B CADM1 PTPRC TLR4 FCER1G SMAD7 IL7R C4BPB IL6 CD160 RAC2 STX7 MALT1 TBX21 TNFSF13 CR1 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT UNC13D IL18 IL18RAP ARRB2 NLRP3 HAVCR2 CD1E KLRK1	down	***
GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN	0.0000198	0.0004989	0.5756103	-0.3340694	-1.749140	166	SC5D ZC3H12C LRRC8C RAPGEF2 STX11 MOB1B FAM49A IGSF6 PILRA TRA2B SBDS EIF1 SDE2 ITGA5 HDC MOB3C TMEM123 NDEL1 TMEM38B ATP10A CSRNP1 COQ10B ZFAND5 UBQLN1 KPNA3 PROCR CLIC5 GPBP1 ETF1 SAR1A PHTF2 SOCS3 OASL LIMD1 WTAP PCGF5 HSD17B12 AP3B1 ECI2 EHD1 JMJD6 TSC22D1 CSDE1 TAGAP PHF11 AMD1 XKR8 SETDB2 SEMA4A RIPK2	down	***
CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN	0.0000000	0.0000001	0.7881868	0.3502226	1.748855	572	HMGA2 TRIP13 FOXM1 HELLS KIF20A CDC45 FANCI ELOVL6 CHEK2 BUB1B NEK2 COIL CCNB1 DNAJC12 CENPF TIMELESS POLQ COA1 GGCT CLGN NDC80 BRCA1 TUBB2B GINS1 GTSE1 HNRNPA1P3 SLC27A2 GMPS SNF8 ASPM STIL EIF2B5 NDUFS6 PLK1 AURKB CENPA AKR1C1 ESPL1 CDC6 SFXN1 GAPDH NNT CCNB2 MCM4 EXOC3 MCM2 SPINT2 RAD54B TYMS CDC25A PRC1 ORC1 AACS EIF3B ALDOC PLS1 GINS4 SHMT2 ZWINT COQ3 NME1 LDHB MELK HMMR DNPH1 NUDT1 MAP7 CEP55 CHAF1A SDHA MKI67 QTRT1 KIF15 PAFAH1B3 TOP2A CCT5 AURKA NUP155 NDUFS2 SLC2A10 POLA2 POLD2 YKT6 KIF2C MCM7 MAD1L1 RRM2 TTLL12 TFR2 WDHD1 RAD54L ENTPD6 KIF11 GPSM2 MCM3 CDC25C CD24 KDELR2 CHEK1 DNAJC9 CC2D1A PFKP TIMM50 BACE2 DSCC1 INPP4B FADS2 TST TADA2A ALDOA RECQL5 PES1 CKS1B CMAS HPS4 NUSAP1 TMEM106C PLOD2 CDK1 EXOSC2 SNX4 BIRC5 ATIC AAGAB NCAPG TRAP1 PSMB5 PSAT1 FEN1 SPAG5 ETFB RECQL4 ITGA2B LAPTM4B QPRT KPNB1 RANGAP1 CHCHD3 SNRNP25 DNAJC17 DLGAP5 ZNF671 GSS PUS1 LMNB2 AARSD1 ADAM28 UROS PTGES2 KIF22 SSRP1 ARL6IP4 ZNF544 TK1 GINS2 ENOSF1 PRMT7 FHL2 NADSYN1 CCT7 DHTKD1 RMND5B KLHDC3 CDC20 CENPM RRP9 ACLY RPA1 MRPL28 SRPK2 MCM5 CD2BP2 HMCES AATF DUS4L RAP2B NEFH CBR1 TSR1 CKAP4 NDUFV1 DDAH1 GLO1 CCNA2 PRR11 VDAC1 CDC42BPA ABCF2 UQCRC1 LPIN1	up	***
GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP	0.0000245	0.0005931	0.5756103	0.3870285	1.748768	172	CEP72 AK4 CHEK2 COIL DNAJC12 TBRG4 IFT122 NUF2 RAD54B CDC25A CCNF ASPHD2 SRPK1 C5orf34 CCDC150 GFPT1 HLTF EME1 ODF2 POLA2 KIF2C MPHOSPH9 CHAF1B FAM162A BRI3BP TOPBP1 MAD2L1 DSCC1 RAD18 PPP5C MNAT1 PTPN3 CBX5 RFWD3 GMNN DNA2 MRPL17 FEN1 SEMA3A PA2G4 RNASEH2A HSPA4L POLR2H ILF2 CCNE1 GNPAT ARHGAP11B FAH PSMA5 METTL22 DHTKD1 SASS6 CKAP5 CPSF4 HNF1B AAAS BCL2L1 CDK5RAP2 DNAJC21 PFKFB4 PRMT5 SEC13 NME7 SMC2 ADRM1 DHRS3 ZBTB32 SEPHS1 NCAPD3 MSRB1	up	***
GO_CELLULAR_AMINO_ACID_BIOSYNTHETIC_PROCESS	0.0013553	0.0160830	0.4550599	0.4311940	1.748441	71	CPS1 GPT GPT2 BHMT PSPH NOXRED1 PHGDH ALDH18A1 PAH SHMT2 PYCR2 ASS1 CAD PLOD2 GOT2 OAT PSAT1 ASNS SLC1A3 NAGS NAT8L GAD1 PYCR1 MTHFD1 SEPHS1 BCAT2 FOLH1 DPYD ASL PLOD1 MTR SHMT1 MTRR PLOD3	up	*
GO_SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX	0.0016266	0.0183127	0.4550599	0.4570122	1.748414	54	LSM5 GEMIN4 PRPF6 SNRPE EFTUD2 SNRPA CD2BP2 SNRPD1 LSM7 DDX23 LSM4 TXNL4A SF3A2 PRPF18 SNRPD2 TXNL4B USP39 PRPF31 SNRNP70 SNRNP200 ZMAT2 PRPF3 SNRPC SF3B2 SART1 SART3 LUC7L3	up	*
MIR148A_3P	0.0000002	0.0000088	0.6901325	-0.3108536	-1.748089	297	EPAS1 PNPLA6 FOXF1 TEK OSBPL11 SECISBP2L LIPA SIK1 DDX6 QKI GPCPD1 ZCCHC2 MTMR10 S1PR1 ARL8B OTUD4 EOGT TXNIP HECW2 ADAM17 ITGA5 KLF6 ITSN2 UBE2D3 RAB14 GPM6A AGO4 NRARP KLF4 LEPROTL1 ROCK1 MAFG EPM2A MPL ITPK1 MGAT4A CADM1 EPS15 DUSP1 PIK3C2A CUL5 PEAK1 PRICKLE2 PDE1C TANC1 NCOA1 TGFB2 SNN TMEM9B ADCY2 VPS37A PHACTR2 MTMR14 MITF BMP3 CNTN4 ATP11A MTMR9 ZNF804A FAM43A RC3H1 HOMER1 TRAK2 GPRC5A CASZ1 WDFY4 AGFG1 ITGA9 PHF3 KIAA0232 BAZ2B SBF2 SKIDA1 MMP15 ATXN1 NPTN ADAMTS15 LTBP1 PLAA CLCN6 ADAM10 DOCK6 MIER1 INO80 EPN2 RTN4 CYB5R4 MAP3K4 ING2 RASSF8 RNF38 MMD CAMSAP2 CNTNAP3B LDLR FEZ2 USP48 ZFYVE26 STARD13 CDC14A CFL2 CDKN1B TGOLN2 EYA3 NOG EFNB2 YWHAB SRSF11 SPTY2D1 WDR47 ARHGEF12 ATP8A1 ATP2B4	down	***
MIR429	0.0000000	0.0000006	0.7477397	-0.2978713	-1.747964	428	SLC24A4 RTKN2 NOVA2 FOXF1 DLC1 DENND5A OSBPL11 TRHDE SECISBP2L RDX MBOAT2 TMOD3 CORO1C VAT1L THAP2 QKI AKAP7 NR3C1 OTUD4 CBL SCN5A TMX4 ZEB2 ERG SEMA6D KIAA0355 DNAJC3 ASAP1 SERINC1 RANBP9 PICALM HIPK3 KLF6 PAG1 DACH1 KANK2 ZEB1 ZYG11B GPM6A FLI1 CPED1 PTPN12 ROCK2 PRDM16 PTPN21 CCDC82 KLF4 ZCCHC24 CLIC4 SPAG9 RECK WASF3 DUSP1 ELK3 ADIPOR2 GNAQ LIN7A AFF3 USP25 PDIK1L PHTF2 PIKFYVE JUN NOTCH1 HMBOX1 SLC14A1 ETS1 MAP4K4 OSTM1 FOXN2 TBC1D12 FERMT2 IPO7 UBAC2 HSPA13 PI4K2B MBNL2 ATL2 FSD1L CASZ1 PPM1F GAS2L3 AGFG1 CDK17 YPEL2 PKIA NAP1L5 ZFAND6 HNRNPD TIMP2 STRN PDS5B TSC22D1 KHDRBS1 NAB1 C16orf72 ATXN1 TOB1 KYNU CLASP2 SBSPON POLK ATAD2B RNF2 GEM SESN1 VASH1 XKR8 MGAT2 IER5 MFAP5 TRAPPC8 RIPK2 FBXO30 ARIH1 DIXDC1 ZDHHC21 ULK2 STK4 RASSF8 COPS8 SCAI B3GNT2 CECR2 DNAJB9 FAM126B PRKG1 CYTH1 MMD CAMSAP2 NRG1 ZFPM2 DNAJB5 EVI5 FEZ2 PMAIP1 ZNF326 REEP1 PSIP1 EXOG CRTAP CFL2 CLIP1 GJC1 HIPK1 FAM8A1 NOG CSNK1G3 CTDSPL2 YWHAB PRTG PPFIA1 UBE2W SGIP1 TSC22D2 MATR3 ADH1B MAP3K1 CNTN1 CCNYL1 NR5A2 RAB11FIP2 MPDZ LRP1 PKD1 MAPK7 SYDE1 NTF3 GPATCH2L ANKRD44 FBXO33 PLXNC1 PUM2 YAP1	down	***
MODULE_146	0.0008726	0.0114538	0.4772708	-0.3800438	-1.747914	73	HCRTR1 GPR17 EDNRB GPR65 CALCRL ADCYAP1R1 C5AR1 CHRNE ADRB1 ADRB2 NPR3 PTGER3 PTH1R S1PR4 HCAR3 PRPH2 HRH1 GPR183 PTGER2 GPR3 FPR2 CCR1 HTR6 CXCR4 ADORA2A GPR171 LPAR6 CX3CR1 FPR1 BDKRB2 FPR3	down	*
BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP	0.0000315	0.0007320	0.5573322	0.3856424	1.747570	175	TRIP13 HJURP FANCI NUP107 COIL NDC80 TTK CDC6 EIF3B NCAPD2 CCT2 NME1 MELK HMMR NLE1 CEP55 BUB1 CCT5 PUS7 NUP155 CBX3 KIF2C RBM28 PFN2 TOPBP1 ACTL6A MAD2L1 RAD51AP1 PHB CKLF NSF PLOD2 UCK2 ATIC NCAPG SEC61G KIF2A EZH2 PSMC4 KPNB1 TPD52L2 TACC3 ANP32E KDM3A CENPM LRRC59 UBE2V2 MED24 C5orf22 WDR45B MARCKS WDYHV1 PRMT5 CCNA2 PRIM1 CANT1 SNRPD2 SNX7 ZWILCH DNAJC10 HGS GPN1 PWP1 ENO1 CYB5B MRTO4 SRM UTP18 ADSL LPCAT1 SRI	up	***
DORN_ADENOVIRUS_INFECTION_48HR_DN	0.0043234	0.0384247	0.4070179	-0.4548119	-1.746948	35	NR4A1 NFE2L2 MCL1 MAP2K3 SRSF5 SDCBP IL6 BCAR3 SGK1 JUNB CD83 KLRC2 EWSR1 EPHA2 NFKBIA CYTH1 HNRNPH1 CCNK	down	*
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN	0.0000000	0.0000005	0.7614608	-0.2935177	-1.746870	461	SIDT2 ARHGAP31 SASH1 EDNRB HHEX TBX3 GLIPR2 SLC16A4 ST6GALNAC3 PTPRB STXBP6 ELF2 PRKAR1A NEDD9 GALNT18 NFATC3 TRIB1 SCARA3 TEX2 SNHG5 KCNAB1 MMRN2 FBXO7 LIFR ASAH1 CSRP1 NLK FOXP1 CAV2 CLN5 STOM FAM122A HNRNPDL TNS1 SPTBN1 PPP1R13B EPM2AIP1 CYP4V2 UBE2D3 CYB5D2 GPM6A ZMIZ1 CYBRD1 FOXO1 SAP30BP DENND6A TSPAN12 ZCCHC24 KLF9 SLC7A8 GRK5 FMNL3 NPAS3 TEF CD302 LBH WASF3 PINK1 MATN2 WFS1 MPC1 GNAQ ZNF706 RUFY3 HES1 SNN HGSNAT MYLIP SLC25A3 IL17D FRY PRDM11 SYNPO2 PKNOX1 SGK1 CTSS PHACTR2 MAGI2 PPP6C AQP3 CYB5R1 KCTD12 BTD PODXL HERC1 SNX1 LPCAT2 SNX22 NIPSNAP3B SNRK TOM1L2 MCAM FOS CALM1 PKIA CHPT1 DDHD2 TCF4 NDUFA5 GNAI1 MIA3 MPV17L MEIS3P1 PLSCR4 ANKRD13A TOB1 STX12 SBSPON RIMKLB N4BP2L2 KAT2B ABI3BP RXRA SESN1 GPX3 SLC35D2 PDLIM5 CPQ PARM1 CEBPD ATP9B EIF4EBP3 NSUN4 TBC1D1 BRWD1 GPD1L BCAM RBMS3 CCDC92 TIMP3 PDE4A RNF38 MTUS1 PRKG1 GSPT1 ENY2 SMAD4 FEZ1 BANK1 PAPSS2 FNBP1 CBX7 STARD13 PHYH EGR1 CDON GHR NR4A2 MAMDC2 NDFIP1 FAM53B CBR4 COX20 HEY1 ABHD14A PEBP1 RMDN1 KIDINS220 AKAP12 POLI MAN1A1 ATOH8 SNRPN MAP3K1 KLHDC1 ZFYVE21 ECHDC3 NKTR AKAP13 SKP1 TPST2 BMPR1A ERLIN2 EIF4E3 ALDH3A2 ST3GAL1 GSN AP4S1 WDFY3-AS2 ZFHX3 RASSF5 CPNE3 RCAN3 TCTA TMEM150C CSGALNACT1 EED ZC2HC1A SRRD RGS5 FARP1 RASSF8-AS1 TMEM64	down	***
GO_PRE_REPLICATIVE_COMPLEX_ASSEMBLY_INVOLVED_IN_CELL_CYCLE_DNA_REPLICATION	0.0027441	0.0271471	0.4317077	0.7880664	1.746810	7	MCM4 MCM2 MCM7 MCM3 MCM6 MCM5	up	*
GO_B_CELL_HOMEOSTASIS	0.0054528	0.0455101	0.4070179	-0.4822052	-1.746720	26	GAPT ADA MIR17HG NCKAP1L RC3H1 CD74 DOCK10 PPP2R3C BCL10 RC3H2 CASP3 BCL2L11 TNFRSF13B TNFAIP3 LYN ABL1	down	*
GSE4984_UNTREATED_VS_GALECTIN1_TREATED_DC_UP	0.0000202	0.0005068	0.5756103	-0.3336042	-1.746704	166	SLPI GLIPR2 LRRFIP1 FLVCR2 GPCPD1 AGTPBP1 IGSF6 ZEB2 LRRFIP2 ASAP1 MALAT1 RASGRP4 LITAF KLF10 SPI1 ADAMTSL4 ARL11 CASP5 DUSP3 ST3GAL2 OSTF1 VASP MAFG KLF7 PLBD1 ERP44 LAPTM5 SNORA28 FCER1G ARL4A DSE AFF1 RBPJ CREBRF SLC8A1 VAMP3 CPEB4 RAB31 WTAP SORT1 SERPINB1 GNG5 GPR84 RXRA BMP2K ITPRIPL2 UBE2D1 S100A4 GLUL GCNT7 ITCH EGR1 CHP1 USP4 SH3BGRL3 AOAH ZYX S100A8 FPR1 ZFP36 C6orf62 DAPP1 ZBED6 ATP2B4 WDFY2 CFLAR RNF19B CYP1B1 GPATCH2L	down	***
GO_NEGATIVE_REGULATION_OF_CELL_MOTILITY	0.0000005	0.0000206	0.6594444	-0.3197333	-1.746319	236	ANGPT4 ACVRL1 HMOX1 DLC1 PPARG ADTRP TIE1 WNT4 ENG CORO1C CITED2 TBXA2R TRIB1 RHOA APOD SEMA6D MIR146A MMRN2 PTPRM MCTP1 ADA ADIPOR1 ABHD6 DACH1 GATA3 RGCC NFE2L2 CRK SFRP1 NODAL RHOB ADARB1 DUSP3 KLF4 THBS1 ADAMTS9 CLDN5 CLIC4 MIR24-2 RECK DUSP1 SMAD7 TBX5 IL24 ARHGDIB STK24 GNRH1 SRF SRGAP2C KANK1 PODN MAGI2 MITF LRCH1 NOTCH1 PTGER4 RRAS FOXO3 EPPK1 CD74 WNT11 TGFB1 CYGB MIA3 KLRC4-KLRK1 MYOCD CLASP2 GPR18 LDLRAD4 FGF2 VASH1 SP100 LIMCH1 SCAI KLRK1 PTEN PRKG1 NRG1 STARD13 ACVR1C GREM1 SERPINE1 C5AR2 CX3CR1 C5 PIP5KL1 NOG MIR640 MIR2355 CALR	down	***
GSE21033_CTRL_VS_POLYIC_STIM_DC_1H_DN	0.0000413	0.0009210	0.5573322	-0.3376864	-1.745623	150	GATA2 COQ2 AQP9 YPEL5 KCNN3 SCARF1 EIF4A1 CD5 LMNA COQ7 CHMP1B BZW1 GLS CRK AKT3 CLK1 BTG3 GPM6A SORBS3 YBX3 PSPN SNIP1 NFKB1 DOCK9 RBMS1 KCNMB1 HPSE LRRC3 DCP1A BCAR3 PPP6C SRSF3 HECA PHF10 LTBP2 JUNB ARHGEF10 HSPA13 REL AGFG1 SLC3A2 AZI2 USP7 ING3 PDLIM1 MEIS3P1 PHLPP2 DOCK6 PITPNA IL18 ARIH1 MEX3C PKNOX2 ITCH NRG1 SFPQ GIMAP4	down	***
IKEDA_MIR133_TARGETS_UP	0.0055742	0.0463424	0.4070179	-0.4267123	-1.743901	40	CDC42 PTPRO ACTR3 SLC6A6 SACM1L RBPJ FMNL2 PPP2CA EBF2 RABGAP1 SNX1 ANKRD12 SEC61B MAFK ARPC5 SGPP1 SLC23A2 DNAJB6 APPBP2 CYLD USP32 NFAT5	down	*
NPAT_TARGET_GENES	0.0000188	0.0004776	0.5756103	0.3785738	1.743814	196	FAM24B ZNF12 PAGR1 THOC3 ANKRD24 SAYSD1 YEATS4 GPI CKLF-CMTM1 MIS18A LRRC27 SPPL2B FAM220A RANBP1 CEP250 CISD1 KIF3B POLA2 LARS2 ENTPD6 SLC2A11 TRMT2A SRRM5 CKLF CBX5 CDK12 GNB1L ATP6V0E2-AS1 PHF12 SEC61G ANKRD26 TMEM79 FADD LIPT2 SMG5 NDUFA11 ATP6V0E2 DNAJA3 MAN1B1 LONP1 JMJD4 PDRG1 CGREF1 CDC7 KDM3A FAM71E1 TIMM13 NPRL3 HMGB3P22 PPP6R1 ZNF248 LSM7 SNAP47 RPP38 MST1P2 MCRS1 SMARCA4 TMEM141 PRPF31 AP001372.2 N6AMT1 NDUFA8 RPRD2 SNORA14B VDAC3 SIRT6 RANBP3 NCAPD3 TK2 NUP93 FAM222B MOK VPS26B RPL36 HINT1 MRPL45P2 ARMC6 EHMT1 XRCC5 SUGP2 PRKAB2 POLD3 COPS7A ZNF473 HNRNPA1 VRK3 GTF3A NVL DAGLB BLOC1S4 EMC10 ZBTB17 TOLLIP-AS1 FUT8 MLST8 VMAC CHCHD4 C10orf88	up	***
REACTOME_POLO_LIKE_KINASE_MEDIATED_EVENTS	0.0054106	0.0453090	0.4070179	0.6230346	1.743516	16	FOXM1 CCNB1 CENPF PLK1 CCNB2 CDC25A MYBL2 CDC25C PKMYT1	up	*
GO_NON_MOTILE_CILIUM_ASSEMBLY	0.0050141	0.0428823	0.4070179	0.4674579	1.743410	48	CEP89 RPGRIP1L MKS1 IFT122 CEP250 BBS1 CCDC13 POC1A IFT172 C2CD3 CENPJ VANGL2 IFT52	up	*
PARK_APL_PATHOGENESIS_DN	0.0056897	0.0470661	0.4070179	-0.4265563	-1.743264	40	PECAM1 MNDA ASAH1 IFI30 SIRPA CES1 SRGN SPI1 CEBPA CTSD SRF BTG1 VAT1 RAB31 JUNB	down	*
GO_ACTIN_FILAMENT_BUNDLE_ORGANIZATION	0.0000458	0.0010066	0.5573322	-0.3450663	-1.743190	132	SWAP70 PHACTR1 DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 INPP5K BAG4 BAIAP2 S1PR1 CDC42 NEDD9 RHOA SPIRE1 LCP1 RGCC SFRP1 SORBS3 RHOB ROCK2 ARRB1 SYNPO SORBS1 ROCK1 MYO1B PLEK ADD1 SRF FAM107A WASF2 SYNPO2 RHOBTB2 ARHGEF10 PTGER4 PIK3R1 PPM1F ESPNL WNT11	down	**
GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_DN	0.0001204	0.0022548	0.5384341	0.3923675	1.742828	145	BBOX1 PTPRT SPICE1 CDH17 SPOCK1 PARPBP DGCR5 BRCA1 METTL1 SPP1 TPX2 CDC25A LIME1 CDT1 MANSC1 ITGA2 EXO1 EMC9 DPY19L1 APOL1 RAD54L SARS2 KDELR2 GAS8 EHHADH PKMYT1 TSHR PLA2R1 PSRC1 ASF1B CDK1 PDK1 SPAG5 G6PC3 ALDH7A1 PKP3 BTN2A3P POLD1 KDELR3 CLINT1 ASRGL1 DYNC1LI2 IGHMBP2 B9D1 RCN3 HDLBP ARSA PCSK5 GTF3C5 IGLV3-19 UBE2C COPZ2 FOLH1	up	**
GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN	0.0000083	0.0002390	0.5933255	-0.3257005	-1.742655	186	USP12 RBMS2 SNX10 SPNS1 GIMAP8 PTPRE CALCRL INPP5A CCNL1 PDE2A GINM1 CHMP1B CYB5A HLX GPBP1L1 CRK UBE2D3 ATP6V1H ATP10A PPM1K CASP1 COQ10B UHRF1BP1L SELL PIK3C2A KLRD1 MBD2 UBASH3B C16orf54 SLC25A33 PPIL4 CREBRF ETF1 S1PR4 SENP3 CD160 SNAP23 PLEKHA3 STAT4 RHOBTB2 KCTD12 UBAC2 KBTBD8 YWHAZ CEBPZ RNF146 AZI2 PPTC7 HBP1 ANKRD13A KTI12 PITPNA GLTP C3orf38 SEC63 VPS4B TRAPPC8 ESYT1 TBC1D1 G3BP2 SDAD1	down	***
GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_DN	0.0000397	0.0008951	0.5573322	-0.3351818	-1.742129	155	EPAS1 SWAP70 SNX10 CD44 CLYBL MYADM GNPTAB FAM49A ZEB2 GINM1 LRRFIP2 ANXA1 ATP2B1 SBDS C1orf21 MAP3K8 SERPINB9 SRGN BAG1 CST3 AHNAK PSTK PLEKHM3 ITGAX HOPX ID2 CCL4 PRF1 DSTN SMNDC1 INSL6 MTPN GABARAPL2 STAT4 PRKCE COBLL1 TCP1 CST7 SLC25A24 NKG7 KLRC2 PIK3AP1 SMPDL3B GSAP PHF11 ACADL NPTN SERINC3 GEM IL18RAP ING2 SAMSN1 RORA PMAIP1 JDP2 PPP2R3C NR4A2 ICOS ITGAL	down	***
GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_UP	0.0001338	0.0024519	0.5188481	-0.3448205	-1.741411	129	SLC24A4 IL1A TBX3 BMP2 EGR2 CCRL2 FLVCR2 TRIB1 IER2 HBEGF ITGA5 BTG2 FZD4 NR4A1 CD93 SPRY2 ID3 ADAMTS9 ATF3 DUSP1 SMAD7 MAFF SLC25A33 SLC25A25 SGK1 OASL SF3B1 JUN JUNB DUSP8 RCAN1 PPP1R15A FERMT2 FOS LMCD1 FOSB DUSP5 TGFB1I1 ACADL ADAMTS15 MACF1 NR2E3 OPN3 CEBPD EDN1 EGR1 SERPINE1 ACSM5 DUSP6 NR4A2 ARL4D ZFP36 FAM53B PIAS2 AKAP12 TNFSF18 NR4A3 PTGS2 GABRD LRRC18 COL4A2 MFHAS1 CYTIP TNFAIP6 GRM8	down	**
GO_INTERLEUKIN_12_PRODUCTION	0.0024637	0.0251105	0.4317077	-0.4141974	-1.741117	47	ACP5 SCIMP IL23A CD36 CLEC7A FOXP1 TRAF6 IL10 MEFV THBS1 NFKB1 TLR4 CCR7 IRF8 TIGIT IRF5 ARRB2 RIPK2	down	*
MODULE_64	0.0000000	0.0000009	0.7477397	-0.2992578	-1.739967	405	SLC6A4 EREG RAMP3 IL1A TEK OLR1 TSPAN4 ASGR1 EDNRB CD55 SFRP4 SPN IL1B SLC16A4 GPR65 PTPRE THBD BMP2 FOLR1 SLC10A1 FCER1A CAV1 CALCRL AQP9 C5AR1 FXYD2 MAL CD1C CD9 CD22 IGSF6 LILRB3 CD8A FGR ANXA1 PTPRM CD5 HBEGF KCNK3 CHRNE MAP3K8 ANPEP PRSS12 MS4A1 STOM ADRB2 IL18R1 GRN CD37 GPM6A PTGIR EPOR PTPRO GPA33 TNFSF12 PTAFR PLAUR GRK5 NPR3 CCL3 LAPTM5 CDKN1A ITGAX PTPRC CXCL2 SELL AXL CCL4 JAM2 CD53 FCER1G CD300C EVI2A INHBA IL7R IL24 PTH1R NCKAP1L PDK4 CD8B S1PR4 HCAR3 FLT1 AREG IL6 IL2RB PRPH2 AQP3 STAT4 HK3 TYROBP IFNGR1 CD83 GYPC GPR183 OSM MAPK4 UNC13B RGS13 GPRC5A GRIK1 MCAM GPR3 NKG7 CD6 FPR2 DUSP5 LRRC32 CD86 CNTNAP1 GLRA1 LGALS3 CCR1 FCGRT RGS2 CLEC2B MLANA RXRA CCL20 ICAM1 LAT SCN7A HTR6 CXCR4 EPHA4 CCR9 EPHA2 ICAM3 DAPK1 CD19 KIT CD3G KLRK1 P2RX1 FGFR1 RORA LDLR NRG1 LPAR6 MS4A2 CSF2RB GHR AQP5 CNR2 DUSP6 KCNJ6 NR4A2 CX3CR1 PRKCH ITGAL FPR1 HAS2 BDKRB2 CD69 GNG11	down	***
MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_21	0.0006198	0.0087840	0.4772708	0.9259679	1.739926	4	HMGA2 CDK4	up	**
GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN	0.0000399	0.0008993	0.5573322	-0.3306711	-1.739921	168	KMO LPIN2 IL1A ADPRH BACH1 QKI MYD88 ZCCHC2 GTF2I ARL8B GIMAP6 SCARF1 IGSF6 IER2 CCNL1 RBM7 TXN BAG1 CASP5 IL10 PLAUR CLIC4 CCL4 CCSER2 INHBA N4BP1 C4BPB AFF1 USP25 HCAR3 OASL SERPINB8 DHX15 CCR7 COBLL1 NDUFV2 ACSL1 AGFG1 CD164 PIM1 GNG5 KCNA3 SOD2 STX12 GATA6 PDE4B GEM ICAM1 IL18RAP TNFAIP8 NBN HSP90AA1 NLRP3 TRAF1 B3GNT2 GPR171 LDLR MT2A GIMAP4 EHD4 TRIM36 PMAIP1	down	***
GO_MITOCHONDRIAL_MATRIX	0.0000001	0.0000056	0.7049757	0.3564691	1.739701	396	CPS1 AK4 BDH1 GPT2 CCNB1 TSFM NMNAT3 TBRG4 THEM4 THEM5 MRPL46 FLAD1 TYMS GLDC SHMT2 MRPS35 COQ3 NDUFB8 NUDT1 MRPL15 PCCB NDUFS2 LARS2 COASY ERAL1 MRPL3 MRPL27 BLOC1S1 MCCC2 PYCR2 TARS2 SARS2 TRMT61B ACSF2 MRPS11 ETFA FDXR MRPS30 MTG1 TST IDH2 TRIT1 MRPL36 FASTK HARS2 MRPL37 CDK1 SSBP1 NUDT2 DMGDH GOT2 OAT ACP6 TRAP1 MCAT DNA2 MRPS2 MRPL17 PDK1 MECR MRPS12 LIPT2 ETFB ATAD3A UQCC2 HYKK PARS2 NADK2 NFS1 DNAJA3 PUS1 ALDH7A1 MRPS34 LONP1 MRPL11 MRPL52 DTYMK MRPL4 ACAD10 DAP3 GFM2 GSTK1 ELAC2 NT5M YARS2 DHTKD1 CHPF NAGS IARS2 CHCHD1 SIRT4 C12orf65 LRRC59 FAHD1 BCL2L1 NAT8L PHYKPL MRPL24 MRPS33 MRPL28 MRPL41 HIBADH ACOT11 SIRT5 MALSU1 MRPL53 PRODH NDUFS7 AMT MRPL51 SUOX PYCR1 MRPL14 SCO2 VDAC1 MRPL55 NME4 ABHD10 ACSF3 RAD51 GADD45GIP1 ATG4D OXCT1 ECHS1 MRPL9 MRPL21 NDUFS8 NUBPL ETHE1 PARG EARS2 MPG TP53 TIMM44 MRPS27 PDP1 BCAT2 MRPL20 MRPL48 TK2 MRPS26 TRUB2 ACAD8 CYP11A1 MTG2 RPUSD3 TFB1M SARDH BCKDK POLRMT MRPS16 ACSM3 DGUOK TOP3A PDK2 MRPL12 CLPP MRPL43 SDHAF1 MRPL2 MCEE GLRX5 COQ5 MPST TEFM GCSH MRPS6 D2HGDH MARS2 CS TXN2 PC LRPPRC MCCC1 MTHFD2	up	***
chr2p16	0.0040327	0.0364091	0.4070179	-0.4468134	-1.738927	36	LHCGR CCDC88A RNU4-49P SPTBN1 VRK2 FOXN2 FBXO11 REL PRORSD1P CCDC85A TSPYL6 STON1 ACYP2 RTN4 PSME4 RNU6-433P NONOP2 CHAC2	down	*
REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_PHOSPHORYLATION	0.0007273	0.0099062	0.4772708	0.4217994	1.738547	82	CHEK2 BRCA1 AURKB TPX2 RBBP8 EXO1 RHNO1 AURKA ATR TOPBP1 CHEK1 MDM2 BRIP1 BLM DYRK2 DNA2 TAF6 PRKAA2 STK11 RAD9A SSRP1 NOC2L RAD50 SUPT16H RPA1 CCNA2 RFC5 CDK5 TP53 TAF4 RAD1 PRKAG1 TOP3A ATRIP RMI1 TP53RK PRKAB2 RMI2 PRKAA1 RFC3 BARD1 RFC4 MAPK14 MAPKAPK5	up	**
KEGG_VIRAL_MYOCARDITIS	0.0045456	0.0398198	0.4070179	-0.4169777	-1.738339	44	CD55 FYN CAV1 CASP9 SGCA PRF1 MYH11 HLA-DQA1 CD80 RAC2 CYCS CD86 ICAM1 ABL2 ACTB EIF4G2 MYH10 ITGAL HLA-DRB1	down	*
GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP	0.0000162	0.0004212	0.5756103	-0.3269318	-1.738290	175	SEMA6A SLC12A6 DENND5A PTPRE LRRFIP1 LINC00472 LMO2 ZCCHC2 ELF2 RRAGC SIRPA NDEL1 MCL1 MTMR6 SRSF5 SDCBP UHRF1BP1L OSTF1 CEBPA DENND3 MAFG ERP44 COTL1 ITGAX ARAP3 FRMD4A TM6SF1 CAPZA2 EVI2A SLC6A6 GNAQ NCOA1 PRCP CYB5R1 PLK3 JUNB IFNGR1 PPP1R15A DAPK2 PSTPIP2 OSM CAP1 RALB PELI1 SLC22A1 FOXO3 SORT1 NAB1 ATP6V0C GNG5 NQO2 ZNF267 SERINC3 BMP2K XKR8 NLRP3 ICAM3 PAK2 DOCK4	down	***
GO_TRANSFERASE_ACTIVITY_TRANSFERRING_SULFUR_CONTAINING_GROUPS	0.0028185	0.0277229	0.4317077	0.4580204	1.738070	53	SULT1C3 HS3ST1 CHST6 SULT1C2 CHST4 GAL3ST1 MOCOS HS3ST5 AMACR TST GAL3ST4 NFS1 CHST3 TRMU SULT1B1 CDK5RAP1 SULT1A3 OXCT1 CDKAL1 ACSM3 CTU2 MPST	up	*
GSE27859_MACROPHAGE_VS_DC_UP	0.0000503	0.0010913	0.5573322	-0.3343633	-1.737597	153	NLRC4 SNX10 RAPGEF2 ARRDC4 CALCRL SUSD2 SLC15A3 TET2 IGSF6 CCNL1 RBM7 B3GNT5 PPP1R15B EIF1 TNIP3 MAP3K8 PPP2R2A FAM122A RAB12 MEFV PTAFR SLC12A4 VASP CCL3 NFKB1 ATF3 IRAK2 JAM2 GCA PTCHD4 DSTN SPRYD7 KPNA3 TANC1 KREMEN1 HCK VPS37A CPEB4 HSPA13 MALT1 HIVEP2 TREX1 PIK3AP1 CCR4 TMX3 SMCR8 IFNAR1 TAGAP PLEKHO2 ABL2 RAB5A NLRP3 CCR9 TRAF1 MCOLN2 GSPT1 SPATA5L1	down	**
GO_POSITIVE_REGULATION_OF_MUSCLE_TISSUE_DEVELOPMENT	0.0039530	0.0359221	0.4070179	-0.4005311	-1.736652	56	HMGCR TGFBR3 TBX2 WNT3A ARNTL TBX5 CYP26B1 MIR17HG LMOD3 RBPJ NOTCH1 CREB1 TGFB1 PIM1 MYOCD GATA6 FGF2 ARRB2 EDN1 FGFR1 MIR548C NRG1 ZFPM2 GREM1 CDON MAPK1 EFNB2	down	*
GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP	0.0000218	0.0005407	0.5756103	-0.3281434	-1.736639	172	CXCL3 CD300LF CPEB2 LIPA EGR2 MYADM PLEKHA1 STX11 CD9 TRIB1 SPCS3 ZEB2 SEMA3B SLC7A7 LIFR EIF1 LITAF HDC HIPK3 GLS SIRPA TIPARP IL10 TBC1D9 AHNAK PDE8A CXCL2 VIM ID2 CCND2 UBASH3B STK24 SERTAD2 JUN RAB31 PTGER4 STX7 PSTPIP2 OSM TAGLN2 YPEL2 NIPA2 TCF4 DUSP5 CD86 PIM1 CCR1 GEM CCR9 MCOLN2 NR3C2 GIMAP4 RNF13 DMXL2 CSF2RB SLC38A2 CD69 SORCS2 FXYD5 SPTY2D1 GPR137B	down	***
GO_LEUKOCYTE_HOMEOSTASIS	0.0008395	0.0111104	0.4772708	-0.3769168	-1.736585	74	GAPT HCAR2 ANXA1 SH2B3 ADA ADAM17 SLC7A11 JAM3 SLC46A2 MPL AXL FCER1G MIR17HG NCKAP1L IL6 SKIL GPR183 RC3H1 CD74 PDE4B LAT DOCK10 PMAIP1 PPP2R3C BCL10 HMGB1 RC3H2 CASP3 BAP1 FLT3	down	*
GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN	0.0000415	0.0009238	0.5573322	-0.3300315	-1.736556	168	CD52 PDLIM2 FYN LY86 WDR74 MYD88 ZCCHC2 INPP5A YPEL5 MSRA FRAT1 TGFBR2 HPS5 GGA2 LCP1 ATP6V1H STK17B MAP1LC3B LAPTM5 RBMS1 SELL LBH CD53 ALOX5AP SNN PKIG METAP1 WASF2 CDC40 INPP5B RNF141 PIKFYVE CD48 HMBOX1 CD83 RASSF2 TNFSF13 BTBD7 DCK TGIF1 PHF11 PIP4K2A RIPK2 SP100 OSER1 CD19 JMJD1C DOCK10 PAK2 DLST CCND3 IL16 BANK1 FNBP1 ARHGEF18	down	***
GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_UP	0.0000447	0.0009853	0.5573322	-0.3308676	-1.736540	165	SIRPB1 SMAD6 CD52 PNPLA6 FCN1 CD55 SPN LTA4H FBP1 FIG4 INPP5K PSMD5 TGFBR2 FGR IER2 TXNIP HBEGF SLC7A7 MASP1 HSPB1 ASH2L HMGN1 CCL22 KIAA0513 BST1 CEBPA CDKN1A RRP8 DUSP1 HTT VAMP5 HLA-DQA1 HES1 HCAR3 SGK1 GAS2L1 JUNB GRB2 WDR7 NDUFV2 PPM1F PLCG2 UBB ALDH3B1 PEA15 JMJD6	down	***
GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN	0.0000253	0.0006053	0.5756103	-0.3270461	-1.736238	174	ADPRH DENND5A FYN CD44 BMPR2 AGTPBP1 TET2 TEX2 HBEGF REV3L RGCC TRAF6 CSRNP1 FOXO1 SPAG9 MGAT4A NFKB1 SELP CD53 EPS15 MBD2 RAP1GDS1 IL7R TP53BP2 AFF1 IL24 ANXA3 BTG1 GPBP1 RYBP SOCS3 UTRN LYRM1 OSM PTGER2 COBLL1 ZNRF3 AP3B1 RRAS CDK17 ZC3H12D GALC PIM1 TMEM107 NRN1 GTF2B BMP2K ANKLE2 MIER1 YAF2 TMEM184B SSH2 FDX1 DOCK10 LYST CAMSAP2 NABP1 ICOS DCUN1D3 SH3GLB1 DRAM2 HEY1 POLI MAN1A1 ITGA6 FNIP1 DUSP22 NR4A3 CCNC IRF4 AKAP13 RNF19B	down	***
MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN	0.0025473	0.0257471	0.4317077	0.4342440	1.736236	67	RACGAP1 MCM2 TYMS CCT2 LSM5 CCT5 PRKDC AIMP2 CHEK1 THYN1 TIMM50 CDK1 SSBP1 EZH2 MRPS12 EFTUD2 CDC23 C1orf131 NDUFA13 IP6K2 CHCHD1 MALSU1 LSM4 CEP152 TBCB RNF7 NMT1 CBWD1 NOMO3 NCAPD3 ZNF367 MRPL43 TEFM RFX7 KEAP1 FIBP EBNA1BP2 PSMD8 IK	up	*
GSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN	0.0000455	0.0010014	0.5573322	-0.3307668	-1.736011	165	SC5D ST6GALNAC3 INSIG1 CCRL2 CLYBL SUSD2 NR3C1 IL1RL1 TEX2 SEMA6D ANXA1 BTG2 PBX3 RNF125 NMUR1 GATA3 NR4A1 RGCC MAPK8IP1 TUBB6 AHNAK SCP2 COQ10B MAFG CDKN1A ATF3 ID2 ARL4A CNOT6L CREM NSMAF ARL5B STAT4 KCTD12 PLK3 UHRF2 GPR183 MALT1 COBLL1 TNFRSF9 DENND4A TIGIT FOSB TTBK2 EHD1 MIR23A IRS2 PLSCR4 RGS2 SERINC3 ARAP2 IL18 IL18RAP ITPRIPL2 CCR9 NFKBIA SAMSN1 LDLR TOX2 EVI5 TRIM36 PMAIP1	down	**
TGFB_UP.V1_UP	0.0000462	0.0010150	0.5573322	-0.3306802	-1.735556	165	SMAD6 DLC1 TBX3 WNT4 RAPGEF2 RCOR1 BMPR2 PLEKHA1 IL1RL1 SLCO2A1 TRIB1 CLCF1 UBL3 ITGA5 ABCG1 KLF10 HLX RGCC PDGFA CASP5 RHOB SNAI1 KLF4 PXDC1 ID3 KLF7 ATF3 JAM2 ELK3 CYP26B1 KANK1 HCAR3 SGK1 JUN LTBP2 HRH1 JUNB FERMT2 SKIL NDST1 LMCD1 CDK17 PKIA WNT11 TFEB JMJD6 TAGLN ETS2 ANKLE2 TNFAIP8 LRP12 EPHA4 MAP3K4 JMJD1C CD1E EDN1 CYTH1 MMD FLT4 SPHK1 SPSB1 TBPL1	down	**
GO_NEGATIVE_REGULATION_OF_MESODERM_DEVELOPMENT	0.0006846	0.0094802	0.4772708	0.9234753	1.735243	4	DKK1 TP63	up	**
GO_CELLULAR_RESPONSE_TO_NUTRIENT	0.0025737	0.0259232	0.4317077	-0.3957924	-1.735074	57	HMOX1 PPARG P2RY1 FOLR1 FYN LPL BAIAP2 GAS6 ATP2B1 FOXA2 SFRP1 KANK2 SSH1 P2RY2 NCOA1 SRF	down	*
GO_TRNA_BINDING	0.0045634	0.0399621	0.4070179	0.4619816	1.734831	49	SLFN13 METTL1 XPO5 XPOT AARS2 NSUN2 SARS2 EEFSEC DTD1 TRMU PUS1 YARS2 IARS2 NSUN6 IGHMBP2 FARSA CTU1 EARS2 MRPS27 DTD2	up	*
GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_UP	0.0000174	0.0004480	0.5756103	-0.3262687	-1.734764	175	ACP5 MS4A7 DCSTAMP PID1 ENG LY86 CORO1C ACER3 GGA2 PDE2A EDEM1 WWC2 CD33 LIFR SLC7A11 DENND6A PXDC1 KLF7 FMNL3 MGAT4A ATF3 CCL4 ARAP3 FCER1G IL7R GLB1 ST6GALNAC6 SLC25A33 CTSS MAGI2 C1QA STAT4 HRH1 RAC2 TYROBP ACKR3 GPR183 NDST1 TIMP2 RELL1 GPR84 DOK2 ACYP2 ETS2 ARAP2 SCPEP1 EDN1 B3GNT2 DLST KIF1B HTRA2 C1QB CX3CR1 DRAM2 PLXDC2 MTSS1 PDE7B MAN1A1 FCGR3A PDPN PTGS2 IRF4 SRXN1 SLC29A3	down	***
GO_METAL_CLUSTER_BINDING	0.0013885	0.0163199	0.4550599	0.4458842	1.734279	59	DDX11 PRIM2 POLE XDH CISD1 NDUFS2 BRIP1 ERCC2 TYW1 DNA2 UQCRFS1 NFS1 POLD1 NDUFS7 NDUFV1 CISD3 RTEL1 CDK5RAP1 NUBP2 RSAD1 NDUFS8 NUBPL CIAPIN1 CDKAL1 DPYD RSAD2 GLRX5	up	*
GO_REGULATION_OF_LIPID_KINASE_ACTIVITY	0.0025737	0.0259232	0.4317077	-0.3955611	-1.734060	57	TEK CDC42 FGR RB1 KLF4 SOCS2 SOCS5 PPP2R5A PIK3R5 NRBF2 FLT1 SOCS3 CCR7 PIK3R1 TGFB1 VAV3 FPR2 CD81 RBL2 FGF2 CD19 KIT	down	*
REACTOME_RESOLUTION_OF_D_LOOP_STRUCTURES_THROUGH_SYNTHESIS_DEPENDENT_STRAND_ANNEALING_SDSA	0.0058943	0.0482524	0.4070179	0.5530860	1.733933	25	BRCA1 RBBP8 XRCC2 EXO1 RAD51AP1 BRIP1 BLM DNA2 RAD51D RAD50 PALB2 RTEL1 RAD51 TOP3A RMI1 RMI2 RAD51B BARD1 WRN RAD51C	up	*
GSE3982_NKCELL_VS_TH1_DN	0.0000638	0.0013250	0.5384341	0.3806648	1.733702	180	ABCC2 HELLS NEK2 GGCT DEPDC1 PHGDH E2F8 CENPA PTTG1 ESPL1 SFXN1 TPX2 CCNB2 CDC25A GINS4 AURKA NUP155 KIF2C RRM2 PDCD5 KIF11 SMYD5 BLM TST SYMPK NOL3 SPRY1 PARP1 CASP6 CKS1B NCAPG2 TMEM106C POLE2 BIRC5 GMNN POLR3K NCAPG STEAP1 PSMB5 RECQL4 QPRT SNRNP25 TUBG1 EFCAB2 DBN1 IL15RA GINS2 KIF20B LRRC20 ENPP2 TCEA2 CKAP5 PELO MCM5 GLO1 MSH2 FAM3C PRIM1 RAD51 N6AMT1 LRRC8B OXCT1 NME7 TNS3 SMC2 POP4 PAICS UBE2C BCAT2 OAS3	up	**
REACTOME_BASE_EXCISION_REPAIR	0.0036771	0.0340628	0.4317077	0.4748840	1.732884	44	POLE LIG3 SMUG1 POLD2 LIG1 XRCC1 PARP1 POLE2 UNG NEIL3 FEN1 MBD4 POLD1 POLB RPA1 RFC5 PNKP PARG MPG NEIL1 APEX1 PARP2 POT1 POLD3 RFC3 POLE4 RFC4 PCNA ADPRHL2 TDG NEIL2 RPA3 POLE3 MUTYH	up	*
GO_GOLGI_LUMEN	0.0026958	0.0267814	0.4317077	0.4319381	1.732823	68	MUC5B PCSK6 MUC13 HS3ST1 MUC4 MUC16 MUC5AC LHB PROC GPC2 MUC20 PROZ PODXL2 MUC6 WNT1 WNT5B PPIL2	up	*
GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP	0.0000354	0.0008098	0.5573322	-0.3294352	-1.732755	164	SEMA3G EPAS1 NLRC4 MGAT3 CD52 GLIPR2 LPXN TRPV2 ARRDC4 GGA2 ADAM17 ABCG2 PARVG ANXA5 MS4A14 C1orf162 ADARB1 KLF11 VASP STK17B TLR4 GNAQ IL7R NCOA1 PRCP TECR CABLES1 AQP3 ETS1 KLHL18 SIGLEC15 NPR1 SNX1 CD151 LMCD1 SIGLEC1 PNPLA3 TGFB1 TSC22D1 ANKRD13A FCGRT DECR1 EGFL7 CALHM2 IQSEC1 PIP4K2A OSER1 LTBP3 TOMM5 EHD4 DISP1 SVIL KCNE1 ATP11B	down	***
GSE23568_CTRL_TRANSDUCED_VS_WT_CD8_TCELL_UP	0.0000249	0.0005981	0.5756103	-0.3263787	-1.732523	178	HHEX ZC3H12C LYL1 LMO2 TMOD3 MYADM INPP5A NCF2 FUCA1 CD22 GGA2 ANXA1 SLC7A7 LIFR ENTPD1 GM2A MAP3K8 IFI30 PBX3 LITAF MS4A1 PPP3CA CYP4V2 TUBB6 CD37 PPP3CC TIPARP MPEG1 KLF4 PLBD1 CLIC4 PDE8A EVI2A HCK MTPN PKIG LIMD1 RAB31 KCTD12 CTSZ GSTO1 SNX2 IRF8 PRKCE NDST1 RHOQ TCF4 SBF2 CBFA2T3 LGALS3 CCR1 ACADL IL18 SPIB ALDH2 S100A4 CD19 CTSC DNAJB9 MCOLN2 IQGAP1 RNH1 EVI5	down	***
chr5q31	0.0001028	0.0019799	0.5384341	0.3889762	1.732441	149	SPATA24 KIF20A PCDHGA10 SPOCK1 NRG2 PCDHGA9 PCDHGA5 PCDHGA7 NPY6R PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 FSTL4 PCDHGA11 PCDHGA8 PCDHGB8P PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 CDC25C NME5 GNPDA1 PROB1 KLHL3 MYOT CXCL14 HARS2 PCDHGA2 RN7SL68P CATSPER3 CDC23 SLC22A5 MTND5P11 SLC4A9 KDM3B ACSL6 SIL1 RAD50 PCDHGB1 BRD8	up	**
BENPORATH_ES_2	0.0040811	0.0367298	0.4070179	0.5397199	1.732429	27	HELLS MCM10 CHEK2 CDC25A MYBL2 ORC1 DSCC1 DBNDD1 EPHA1 L1TD1 DTYMK ETV4 RRP9 DNMT3A	up	*
REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT	0.0019910	0.0213723	0.4317077	0.4528242	1.732392	54	CHEK2 CCNB1 BRCA1 RBBP8 EXO1 TP53BP1 RHNO1 ATR CDC25C TOPBP1 CHEK1 BRIP1 BLM CDK1 DNA2 RAD9A RAD50 RPA1 UBE2V2 UIMC1 RFC5 TP53 RAD1 PIAS4 TOP3A ATRIP RNF8 HERC2 RMI1 RMI2 RFC3 BARD1 RFC4	up	*
MIR148B_3P	0.0000002	0.0000077	0.6901325	-0.3084007	-1.732300	296	EPAS1 PNPLA6 FOXF1 TEK OSBPL11 SECISBP2L LIPA SIK1 DDX6 QKI GPCPD1 ZCCHC2 MTMR10 S1PR1 ARL8B OTUD4 EOGT TXNIP HECW2 ADAM17 ITGA5 KLF6 ITSN2 UBE2D3 RAB14 GPM6A AGO4 NRARP KLF4 LEPROTL1 ROCK1 MAFG EPM2A MPL ITPK1 CADM1 EPS15 DUSP1 PIK3C2A CUL5 PEAK1 PRICKLE2 PDE1C TANC1 NCOA1 TGFB2 SNN TMEM9B ADCY2 VPS37A PHACTR2 MTMR14 MITF BMP3 CNTN4 ATP11A MTMR9 ZNF804A FAM43A RC3H1 HOMER1 TRAK2 GPRC5A CASZ1 WDFY4 AGFG1 ITGA9 PHF3 KIAA0232 BAZ2B SBF2 SKIDA1 MMP15 ATXN1 NPTN ADAMTS15 LTBP1 PLAA CLCN6 ADAM10 DOCK6 MIER1 INO80 EPN2 RTN4 CYB5R4 MAP3K4 ING2 RASSF8 RNF38 MMD CAMSAP2 CNTNAP3B LDLR FEZ2 USP48 ZFYVE26 STARD13 CDC14A CFL2 CDKN1B TGOLN2 EYA3 NOG EFNB2 YWHAB SRSF11 SPTY2D1 WDR47 ARHGEF12 ATP8A1 ATP2B4	down	***
GO_CYTOKINE_BINDING	0.0004095	0.0062746	0.4984931	-0.3478924	-1.732282	106	ACVRL1 SOSTDC1 GREM2 ENG CCRL2 BMPR2 TGFBR3 IL1RL1 IL1RN TGFBR2 CD36 LTBP4 LIFR FZD4 IL18R1 CD93 TCAP THBS1 NRROS IL2RB IFNGR1 CCR7 ACKR3 CD74 CCR4 LRRC32 IFNAR1 CCR1 LTBP1 CCR6 CXCR4 CCR9 KIT LTBP3 NRP2 GREM1 GHR CX3CR1 ITGB1 ZFP36 CD109 NOG	down	**
PYEON_HPV_POSITIVE_TUMORS_UP	0.0008007	0.0107076	0.4772708	0.4202677	1.732234	82	LINC00342 HELLS SLFN13 ABCA17P CENPF CDCA7 UHRF1 TYMS DTL MCM8 C5orf34 STAG3 KIF15 KNTC1 SYCP2 MPHOSPH9 MCM3 LIG1 KLHL35 CDKN2C CENPJ ZNF789 EZH2 MIR3939 INTS7 CDK3 CDC7 CENPK MEI1 FBXO22 TRIM56 ATAD2 ZSCAN16 TM7SF3 WDR76 MON2 E2F7 ZNF367	up	*
GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP	0.0001538	0.0027603	0.5188481	-0.3429554	-1.731992	129	IL1A TBX3 GPR65 EGR2 CCRL2 TRIB1 IER2 HBEGF BTG2 LITAF NR4A1 CD93 SPRY2 RHOB IL10 KLF4 COQ10B CXCL2 ATF3 DUSP1 PIK3C2A MAFF SLC25A33 SLC25A25 CD80 PRDM11 IL6 DDHD1 SGK1 JUN PLK3 JUNB RCAN1 PTGER4 FOS SPRY4 RBKS FOSB DUSP5 LRRC32 RGS2 GEM CEBPD EDN1 NRG1 MT2A PMAIP1 EGR1 SERPINE1 DUSP6 NR4A2 KIAA2026 ARL4D ZFP36 ADAMTSL3 AKAP12 HMGB1 TNFSF18 NFIL3 NR4A3 PTGS2 IMPACT NFKBIZ DUSP2	down	**
KEGG_LEISHMANIA_INFECTION	0.0026523	0.0264228	0.4317077	-0.4014996	-1.731971	53	IL1A IL1B MYD88 NCF2 TRAF6 IL10 NFKB1 TLR4 HLA-DQA1 TGFB2 JUN IFNGR1 JAK1 FOS CR1 TGFB1 TAB2 NFKBIA CYBA MAPK1 ITGB1 NCF1 HLA-DRB1 FCGR3A PTGS2	down	*
MORF_WNT1	0.0039405	0.0358546	0.4070179	0.4368731	1.731799	64	KIF1A MYBPH BHMT RPGRIP1L DOC2A CYP4F11 PDE9A FSTL4 TNNT2 NLE1 ODF2 TEKT2 WNT1 PHKG2 SPAG8 PTGDR2 ATP2A1 VPS41 ZNF239 NTN3 COX10 SEC14L2 RPGRIP1	up	*
PID_KIT_PATHWAY	0.0037536	0.0345716	0.4317077	-0.4086545	-1.731797	50	CBL SH2B3 STAT5A EPOR PTPRO MATK MITF PIK3R1 GRB2 FOXO3 MAPK8 TEC CREBBP KIT PTEN GRB10	down	*
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_ACTIVATION	0.0011450	0.0141248	0.4550599	-0.3722193	-1.731149	80	CD55 SPN TGFBR2 IL23A ANXA1 FOXP1 HLX GATA3 IL18R1 FUT7 SOCS5 SMAD7 NCKAP1L CD80 IL6 CD160 PTGER4 CD83 GPR183 MALT1 RC3H1 TBX21 RUNX3 CD86 CD81 IL18 SEMA4A RIPK2 NLRP3	down	*
GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP	0.0000506	0.0010962	0.5573322	0.3806269	1.730421	179	KIF20A FAM81A CDC45 BUB1B POLQ MND1 TTF2 PIF1 GTSE1 TRAIP MSTO1 FLAD1 PAK6 TPX2 SMPDL3A PRC1 CCNF DTL MCM8 LIME1 NCAPD2 MELK EXO1 PAQR4 PAFAH1B3 AUNIP EXOC4 BRI3BP AHCY RAD51AP1 ABCB9 SPC24 PERP BRIP1 PML ERCC2 KNSTRN RNF216 DCLK1 CBX5 ASF1B STON2 CENPH ARPC1A ADAP1 DNA2 AP5Z1 SAPCD2 RTP4 ABHD4 SERHL2 SLC37A4 FHL2 CENPK DHRS1 POPDC2 NEK4 PYGO2 HMCES IL12RB2 B9D1 SHCBP1 LPGAT1 CARHSP1 MXD3 VDAC3 UQCRQ LIF UBE2C COX6B1 NUP93 CYP11A1 TEX9 LYPLA1	up	**
RUTELLA_RESPONSE_TO_HGF_UP	0.0000000	0.0000015	0.7337620	-0.2990842	-1.730352	380	CXCL3 ACP5 KMO SC5D IL1A OSBPL1A IL1B FBP1 CYP27A1 SNX10 DCSTAMP LPXN RDX CCRL2 ST3GAL6 AQP9 ALAS1 CD9 LAMP1 EPB41L3 RFTN1 TEX2 PLA2G7 MCTP1 ASAH1 ENTPD1 GM2A CSRP1 CYB5A TNIP3 HSPB1 ANXA5 LITAF ABCG1 GLS SLC7A11 STOM LAIR1 AKT3 CRTAM CES1 ZFYVE16 TFRC TXN ATP6V1H APOC1 CD58 EPB41L2 IL10 CCL22 KCNMA1 ACSL3 KLF9 DAB2 CTSD CCL3 CDS2 CTBS TM6SF1 CCSER2 INHBA PINK1 MATK ZNF706 N4BP1 TBC1D4 CRIM1 HEXB ARL6IP5 CD80 PKNOX1 SGK1 RAB8B PDCD6IP C1QA MITF VAT1 LTBP2 DUOX1 JAK1 TMEM251 CCR7 ZNF804A ATP13A3 CXCL5 MOB1A SLC3A2 POGLUT1 GRSF1 RHOQ NKG7 RIN2 EMC7 TIMP2 TFEB TSC22D1 DUSP5 DYNC1LI1 CD81 SOD2 LGALS3 CCR1 KYNU IL18 TNFAIP8 SLC31A1 CALHM2 ATP9B TBC1D1 TRAF1 PLGRKT FDX1 BCAT1 CD1E FOXJ2 LDLR DOCK4 MT2A CREG1 ARFGAP3 ACAT1 SPHK1 DMXL2 ATP6V0A1 TMEM184C PHYH	down	***
GO_MITOTIC_DNA_REPLICATION	0.0042779	0.0381384	0.4070179	0.6544117	1.730045	13	CDC45 CHEK2 GINS1 MCM4 MCM2 MCM3 LIG1 MCM6 RAD51 BCL6	up	*
GO_TUBE_MORPHOGENESIS	0.0000000	0.0000000	0.8513391	-0.2761148	-1.729640	707	TRIM71 ANGPT4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SOSTDC1 SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK DLC1 TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB BMP2 CDH5 ENG FOLR1 ECSCR SOX17 CAV1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 HSPG2 HEG1 RHOA ZEB2 APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM WNT2B RAP1A ITGA5 CLEC14A HSPB1 LUZP1 FZD4 FOXP1 ANPEP HLX GATA3 NR4A1 JAM3 RGCC TRAF6 NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A ZEB1 SPI1 TCAP MTHFR PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 ROCK2 AMOTL1 NRARP TBX4 NPNT TNFSF12 TSPAN12 KLF4 ROCK1 VASP THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HPSE ID2 MIR24-2 RECK PIK3C2A ELK3 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS DCHS1 HES1 PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ GZF1 HESX1 FLT1 AREG IL6 WASF2 PKNOX1 CD160 PSEN1 NDNF JUN NOTCH1 ETS1 CTSZ JUNB JAK1 RHOJ PODXL	down	***
DAZARD_RESPONSE_TO_UV_SCC_UP	0.0005792	0.0083043	0.4772708	-0.3657013	-1.729510	85	CXCL3 SC5D IL1B MIR22HG CITED2 PRKAR1A ANAPC15 SLC11A1 UBE2D3 ITM2B CXCL2 ATF3 ID2 ANXA3 ARHGDIB SNX3 IL6 SDHD YWHAZ RALB FOS TOB1 KYNU ME2 CCL20 JUND RTN4 CDKN1C SRSF10 PMAIP1 CSF2	down	**
NIKOLSKY_BREAST_CANCER_20Q12_Q13_AMPLICON	0.0008859	0.0115989	0.4772708	0.4037759	1.728846	111	RBBP8NL ZMYND8 TSHZ2 BCAS1 TOMM34 LIME1 ZFP64 OSBPL2 CYP24A1 C20orf197 AURKA SYCP2 FAM209A SAMD10 ZNF512B ABHD16B DIDO1 BCAS4 PRPF6 UCKL1 TPD52L2 ZGPAT ARFRP1 MRGBP ADNP ATP9A SALL4 CABLES2 TCEA2 LSM14B PPP1R3D GID8 STMN3 OGFR ARFGAP1 RTEL1 ZNF217 ADRM1 PFDN4 TAF4 NPEPL1 ZNF831 ZBP1 MTG2 SS18L1 PMEPA1 CSTF1	up	*
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_DN	0.0000243	0.0005895	0.5756103	-0.3247433	-1.728332	177	SLC24A4 EPAS1 ACP5 HHEX FABP4 MNDA CLEC3B KL LY86 CLEC10A AVPI1 DPEP2 CARD16 ASAH1 GNGT2 ECHDC1 M1AP RB1 GRN APOC1 SORBS3 CYBRD1 CFD DUSP3 AHNAK CPVL SLC7A8 ZADH2 TPP1 LINC00324 BACE1 SPIN1 CCNY CTSS SNX29 DDX17 BTD PIK3R1 MBNL2 SIGLEC15 OGFRL1 GAS2L3 FXYD6 ITGA9 CD1D ZBTB1 FAM228B BAZ2B EXOC1 VPS39 PLA2G15 IST1 CEBPD PIP4K2A SLC2A9 METTL7A NHLRC3 LPAR6 CNOT8 SPOPL MIS18BP1 SLC35A1 STARD13 ATP6V0A1 HERPUD1 NR4A2 C5 TREM2	down	***
GO_MYOBLAST_DIFFERENTIATION	0.0017170	0.0190284	0.4550599	-0.3834909	-1.727980	68	EPAS1 SOSTDC1 TBX3 HMGCR KCNAB1 TBX2 RB1 TCF7L2 REST ID3 PLEKHM3 AKIRIN1 SRF BTG1 RBPJ NOTCH1 DDX17 IFRD1 DDX5 TGFB1 MYOCD MBNL1 IL18	down	*
MODULE_485	0.0058120	0.0477673	0.4070179	0.4633008	1.727906	48	GRIK2 BDH1 POLE CDC6 MYBL2 GSDMB BUB1 MSX2 AURKA RRM2 HOOK1 CD24 FADS2 SSUH2 UNG DLGAP5 ARHGEF16 CELF4 NT5DC2 CCNA2 RBM42 CAP2 MCF2L2 NQO1 SLC40A1 PDK2	up	*
GO_CHROMOSOME_LOCALIZATION	0.0033833	0.0320836	0.4317077	0.4347116	1.727885	65	SPICE1 CCNB1 CENPF NDC80 KIF14 NUF2 CDCA8 CDT1 SPDL1 BOD1 KIF2C MAD1L1 CDCA5 PSRC1 SUN1 SPAG5 TRAPPC12 KPNB1 CDC23 DLGAP5 KIF22 CENPQ MEI1 CHMP4C KATNB1 NUP62 CHMP1A CHMP2A CENPE RRS1 CHMP6 DYNC1H1	up	*
WALLACE_PROSTATE_CANCER_UP	0.0041440	0.0371727	0.4070179	0.5922312	1.727472	19	BDH1 LIG3 POLD2 AMACR SOX4 AHCY DAP ST14 TSTA3 PRSS8	up	*
MORF_CCNF	0.0019456	0.0210079	0.4550599	0.4280788	1.727448	70	TRIP13 FANCI BRCA1 GTSE1 CENPA CCNF WDR62 MKI67 HLTF LARS2 MAD2L1 PPP5C DNA2 OARD1 TTI1 KPNB1 FANCG ANP32E PLEKHB1 CDC7 CPSF4 RRP9 UBE2V2 RFC5 LPGAT1 BMS1 ARHGAP11A PAXIP1 TIMM44 SIGMAR1 NELFA	up	*
GO_NEGATIVE_REGULATION_OF_NEURON_DIFFERENTIATION	0.0000243	0.0005895	0.5756103	-0.3245047	-1.727062	177	SLC6A4 TNR DAB1 SEMA6B SEMA3G SEMA6A EDNRB DENND5A RAPGEF2 DDX6 CTDSP1 RHOA SEMA6D ASAP1 SEMA3B PAQR3 EIF4E PPP3CA WNT3A ZNF365 LRP4 PTPRO TRIM46 REST ID3 VIM ID2 PAFAH1B1 RUFY3 HES1 KREMEN1 SRGAP2C KANK1 MYLIP ID4 CNTF PSEN1 NOTCH1 CTSZ CNTN4 BAG5 IFRD1 LSM1 RTN4R TRAK2	down	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN	0.0000513	0.0011063	0.5573322	-0.3322590	-1.726938	155	OSBPL1A GPR65 EGR2 IBA57 PRPF38A S1PR1 BCL2A1 DENND2C PPM1D PDCL IER2 BTG2 ZNF410 PRSS12 ZBTB8A NR4A1 NFE2L2 ADO EVI2A MIR17HG RASGEF1B C2orf69 CREM CRNKL1 ETV3 ARL5B CYCS PALM PNPLA8 KLHL18 MBNL2 GPR183 KBTBD8 NUDT15 NAA30 HSF5 VPREB3 C4orf36 CNTNAP1 TAGAP GPR18 FAM98B CCNH GEM SLC31A1 TXNDC15 IER5 FBXO30 DNAJB9 LPAR6 PUS3 EGR1 NR4A2 YRDC DNAJB4 CD69 CYP51A1 CHAC2 BCL10 TRMT10C FNIP1 NR4A3 ZNF331 DUSP2 ENPEP FBXO33 CSTF2T	down	**
NIKOLSKY_BREAST_CANCER_16P13_AMPLICON	0.0006403	0.0090149	0.4772708	0.4113331	1.726920	93	ZG16B HBA1 HBA2 WDR90 KREMEN2 PAQR4 EME2 PKMYT1 CLDN9 CCDC78 POLR3K WDR24 SNRNP25 WFIKKN1 TELO2 MRPS34 NHLRC4 LMF1 CHTF18 NPRL3 FAHD1 RPUSD1 MRPL28 SPSB3 CAPN15 TSC2 HAGHL NME4 NUBP2 PRSS22 RHOT2 UNKL MAPK8IP3 MPG ZNF205 TBL3 MSRB1 PIGQ RAB40C AXIN1 ZNF598 RAB11FIP3 TRAF7 PDIA2 RAB26	up	**
PRC2_EED_UP.V1_DN	0.0000841	0.0016674	0.5384341	0.3828890	1.726914	168	CA9 HELLS CDC45 MCM10 BUB1B PAGR1 ANKZF1 DBF4B PLK1 CDCA8 MCM2 MYBL2 ORC1 ACY1 AP1G2 MICALL2 TOP3B KIF23 QTRT1 FRS2 ODF2 POLA2 CLSPN LIPE RAD54L PCDHGA3 PHKG2 CHAF1B ABCB9 TRMT2A CAD FADS2 SYMPK GLE1 IDH2 ERCC2 BTBD2 INCENP APLP1 ASF1B EXOSC2 C1orf112 PACS1 TNK2 RECQL4 RANGAP1 SLC35C2 CHST3 TACC3 DLK2 PRMT7 LRRC20 POLD1 SLC26A1 TNS4 ZNF446 MCM5 SURF2	up	**
GO_NEGATIVE_REGULATION_OF_TRANSPORT	0.0000001	0.0000047	0.7049757	-0.2996956	-1.726782	368	FFAR4 RAB11FIP1 CD300LF FOXF1 HMOX1 ADTRP SFRP4 IL1B PRKG2 P2RY1 PLA2G10 PID1 INSIG1 PCSK9 STXBP6 INPP5K BAG4 CAV1 NEDD4L HMGCR MIR27B GAS6 CD22 KCNAB1 APOD CD36 ANXA1 MIR146A CARD16 MCTP1 ADA CD33 HECW2 RAP1A RAB33B PICALM ANXA5 PPP3CA SIRPA RGCC SFRP1 SRGN TXN APOC1 IL10 FABP5 SDCBP TACR2 REST THBS1 KLF7 UBQLN1 DPH3 NFKB1 MIR24-2 FRMD4A PTGER3 INHBA OXSR1 GNAI2 TBC1D4 CALM2 SNX3 PKIG ARL6IP5 VAMP3 LRRTM2 APPL1 NOTCH1 CARD8 GSTO1 PTGER4 UBAC2 PRKCE OSM PXK PPM1F CD34 CALM1 ATG3 PKD2 PKIA CD74 EPHA3 NUP153 STXBP3 PEA15 SERPINB1 HECW1 MTMR2 LRRC32 IRS2 MPV17L LGALS3 ANKRD13A CRY1 ACTN2 RGS2 SYT11 GEM ICAM1 CTTNBP2NL OSR1 VPS4B NLRP3 SP100 ISCU BOK SREBF2 EDN1 PTEN NRG1 GRB10 PSMD9 ENY2 ATF4 BANK1 PIM3 KALRN ACVR1C CHP1 C5AR2 KCNE1 FKBP1B CRBN	down	***
GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_UP	0.0001405	0.0025565	0.5188481	0.3804233	1.726200	176	CEP89 NUP107 CCDC34 PSPH PBK KIF18B TTF2 DEPDC1B E2F8 GTSE1 KCNQ5 RAD54B TYMS MCM8 SHMT2 TAMM41 RANBP1 CISD1 KIF23 MKI67 FANCA TOP2A CENPL E2F2 RRM2 SMYD2 CDCA5 MRPL27 SMYD5 ZNHIT1 AHCY DSCC1 KNSTRN CBX5 C1orf112 NUDT2 GMNN SEC61G NUP205 MZT2B LMNB2 DTYMK MYBBP1A MFSD2A GINS2 DAP3 FUCA2 C12orf73 NUP85 DCUN1D5 MRPL41 NMNAT1 SNRPD1 LANCL2 KATNB1 POLR2I ETV6 CCNA2 SMARCA4 PRIM1 HDLBP RNF157 MRPL21 NDUFS8 CISH NDUFB7 ZNF367 PPP1R14B NCAPH GEMIN2 TEX9	up	**
GO_MITOCHONDRIAL_PROTEIN_COMPLEX	0.0000267	0.0006380	0.5756103	0.3722871	1.726177	207	CHCHD6 MRPL46 ANKZF1 NDUFS6 MRPS35 AGK NDUFB8 SDHA MRPL15 NDUFS2 MRPL3 MRPL27 MCCC2 TIMM50 MRPS11 MRPS30 MRPL36 MRPL37 DNA2 MRPS2 MRPL17 PDK1 MRPS12 CHCHD3 UQCRFS1 NDUFA11 SPG7 COA3 FOXRED1 MRPS34 MRPL11 MRPL52 MRPL4 DAP3 DNAJC11 NDUFA13 TIMM13 C12orf65 MRPL24 MRPS33 MRPL28 MRPL41 ROMO1 MALSU1 MRPL53 NDUFS7 MRPL51 NDUFV1 MRPL14 VDAC1 MRPL55 UQCRC1 TOMM40L MCU MRPL9 MRPL21 MICU1 NDUFA8 NDUFS8 UQCRQ MRPS27 MRPL20 MRPL48 NDUFB7 MRPS26 IMMP2L BCKDK TOMM7 POLRMT MRPS16 PDK2 MRPL12 MRPL43 MRPL2 TOMM40 TIMM10 MRPS6 NDUFB2 TIMM9 MCCC1 COX6A1 NDUFA4L2 NDUFA9 SDHC WDR93 MRPS7 MRPL35 MRPL13 MRPL33 NDUFA10 BCKDHA MFN1 NDUFB10 TIMM23 IMMP1L NDUFS4	up	***
SGCGSSAAA_E2F1DP2_01	0.0002417	0.0040416	0.5188481	0.3902327	1.726144	140	GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 MCM4 MCM2 CDC25A EFNA5 C19orf57 CAND1 RANBP1 WDR62 PAQR4 AP4M1 MCM7 CLSPN RRM2 PRKDC MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 POLE2 GMNN E2F1 UNG THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2	up	**
CSR_EARLY_UP.V1_UP	0.0001169	0.0022014	0.5384341	-0.3419629	-1.725770	134	USP12 KLF13 GATA2 NUP54 ZBTB2 MOB1B TBX2 EIF4A1 HBEGF CD33 KLF10 HLX ZNF697 SPRY2 PTPN12 MAP2K3 SNAI1 PLAUR REST ID3 ACTR3 DNTTIP2 ELK3 CCDC59 SMAD7 INHBA BCAR3 ETS1 DNAJA1 SPRY4 PTP4A1 UTP3 PHLPP2 TIMM22 AMD1 ITPRIPL2 SRP72 RIPK2 KPNA4 C21orf91 EHD4 FJX1 ZNF800 MSANTD3 UBE2N DDX21 TRMT10C SREK1IP1 PTGS2 YOD1 CBFB PNP ST3GAL1 FAM107B GNL2 EIF4A3 RNPS1 DIS3 MYO9B PTPN1 TNFRSF12A TOP1	down	**
GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP	0.0000103	0.0002849	0.5933255	-0.3270425	-1.725538	171	HHEX RAPGEF2 THBD SIK1 CTSW ST3GAL6 VAMP2 MAL HEG1 TXNIP TOE1 EIF1 BTG2 LITAF CLK1 SORBS3 TIPARP MOAP1 LEPROTL1 TPP1 LAPTM5 RRP8 UBE2B PER1 IL7R PLCD1 NCOA1 BTG1 KCNA5 AREG CD48 JUNB DUSP8 CCR7 DDX5 YWHAZ SRSF6 ZBTB1 HBP1 GABARAPL1 TOB1 PDE4B JUND RBL2 CXCR4 IFFO1 RPS13 CYTH1 EIF4A2 ARHGEF18 CDC14A LHFPL2 HAS2 TUBA1A TSC22D2 MATR3 CHKA FCHSD2 RANBP2 TERF1 PNISR FASN HOXA5 EPHB6 RPL32 JOSD1 PADI2 PYGM RPS15A USP34 VIPR1 CD59	down	***
chr14q12	0.0030951	0.0298591	0.4317077	0.4578916	1.725424	51	NOVA1 COCH LTB4R2 NOP9 EMC9 REC8 TGM1 LTB4R PSME2 NFATC4 ARHGAP5-AS1 HECTD1 DHRS1 RNU6-455P RNF31 NEDD8 AKAP6 HEATR5A ARHGAP5 NUBPL GMPR2 TSSK4 DTD2 RIPK3 DCAF11 KHNYN HIGD1AP17 PSME1 CBLN3 TM9SF1	up	*
GO_DNA_POLYMERASE_ACTIVITY	0.0046363	0.0404059	0.4070179	0.5375168	1.725358	27	POLQ POLE POLM POLA2 POLD2 POLN TERC POLE2 TEP1 POLL POLD1 POLB	up	*
GO_PHOSPHOLIPASE_C_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.0034591	0.0326571	0.4317077	-0.3819814	-1.725326	65	GPR17 EDNRB F2RL3 LHCGR P2RY1 GPR65 ADRA1D C5AR1 S1PR1 NMUR1 GPR4 NPR3 P2RY2 PTGER3 GNAQ GPR157 PTH1R HRH1 ADRA1A HOMER1 FPR2 ACTN2 GPR18 EDN1 LPAR6 C5AR2 CX3CR1 FPR1 FPR3 GPR55	down	*
GCM_HBP1	0.0022211	0.0232293	0.4317077	-0.3892198	-1.724300	60	USP47 RANBP9 SLAIN2 FOXJ3 LAMTOR3 ZFAND5 CUL5 PPIL4 PRKRA COPS2 NAA30 RRN3 RNASEK YTHDF3 MAP3K2 HBP1 HNRNPH3 COMMD9 USPL1 TAB2 FNBP4 C1orf52 MED17 TBC1D23 SCAF8 KANSL3 MTDH PHACTR4 PRPF8 ZC3H14 PCNP IRF2BP2 RBM25 ZNF644 PPM1B	down	*
GO_PYRIMIDINE_NUCLEOTIDE_BIOSYNTHETIC_PROCESS	0.0041120	0.0369434	0.4070179	0.4967235	1.723983	36	GPAT2 TYMS UMPS TAMM41 NME1 NME9 NME5 CAD UCK2 UCKL1 UPP2 DHODH DTYMK AGPAT5 LCLAT1	up	*
GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_UP	0.0001347	0.0024669	0.5188481	0.3860884	1.723881	152	SPATA24 CHEK2 NEK2 CCDC34 TIMELESS UBE2T DEPDC1 CDK4 RACGAP1 IFT27 ESPL1 E2F3 FIGNL1 UHRF1 GINS4 SPDL1 TAMM41 DNPH1 KNTC1 BUB1 NUP155 POLA2 POC1A CDCA5 WDHD1 LIG1 ORC6 MAD2L1 DSCC1 RAD18 NCAPG2 CDKN2C NSF GMNN PSMB5 GNPNAT1 PSAT1 NEIL3 TAF6 RANGAP1 NMRAL1 MNS1 TUBB2A TK1 ANP32E CEP128 TDP1 LANCL2 GINS3 ALG8 ECH1 UQCRC1 CCDC181 CHMP2A NDUFS8 VDAC3 SWI5 PPIA COX6B1 KIF24 TRPC4AP ACSL5	up	**
GSE3982_DC_VS_NKCELL_UP	0.0000264	0.0006299	0.5756103	-0.3237017	-1.722788	177	GPD1 SLC31A2 KMO SLC47A1 TAL1 PPARG CAT CCDC88A FCER1A FOSL1 CYB5R3 ALAS1 CD9 IL1RN LAMP1 SCARF1 IGSF6 GM2A ANPEP HLX ABHD6 RGCC TNS1 SLC19A1 ATP6V1H CCL22 DRAM1 CDKN1A ATF3 ARL4A FKBP15 MMP19 CLN8 SGK1 ESD SLCO2B1 MITF RAB31 CTSZ PODXL PABPC4 CD83 NPR1 PSMD12 PEA15 CTNNAL1 MCUR1 LRRC32 UTP3 LGALS3	down	***
TGAATGT_MIR181A_MIR181B_MIR181C_MIR181D	0.0000000	0.0000005	0.7614608	-0.2956373	-1.722561	414	TRIM71 IL1A ADCY9 DPYSL2 MBOAT2 LONRF1 BAIAP2 QKI CDH13 BMPR2 SRSF7 INPP5A SFR1 NR3C1 OTUD4 ZBTB4 ATP2B1 CACNA2D2 PBX3 PICALM NLK SPIRE1 FOXP1 KLF6 RNF182 GLS MED26 SLC25A37 AKT3 ADARB1 KCNMA1 LIN7C ADO TMED5 GAPVD1 PER2 RECK UBE2B EPS15 CCSER2 SMAD7 ELMSAN1 CUL5 UNC5A BCLAF1 TBC1D4 AFF1 CRIM1 PI4K2A SNN C2orf69 MTPN PDK4 KANK1 GPBP1 CREBRF ETF1 SLC25A3 FMNL2 SLC25A25 METAP1 NSMAF PLEKHA3 HECA WSCD2 CPEB4 ETS1 CNTN4 MTMR9 FBXO11 PI4K2B MBNL2 PRKCE CREB1 RBM22 TRAK2 CGGBP1 EPC2 MEAF6 ACSL1 AGFG1 FOS SPRY4 YTHDF3 SYPL2 ZFAND6 AP1G1 PHF3 BAZ2B YTHDF2 DUSP5 CBFA2T3 LRRC32 IRS2 ATXN1 PPP3R1 NPTN GATA6 KAT2B ABI3BP PDLIM5 RLF FKBP1A CTTNBP2NL INO80 ACAP2 LRP12 EPHA4 TBC1D1 IPO5 MEX3C BRWD1 GPD1L G3BP2 PKNOX2 CUL3 TIMP3 DOCK10 FAM126B DAZAP2 FAM13B NAA15 GRB10 EIF4A2 PUM1 PURB PPP1CB RABGEF1 CBX7 KLF15 PLAG1 GREM1 CDON MB21D2 TBPL1 CLIP1 ZNF800 MAPK1 MYH10 MAMDC2 CCNK SLC38A2 EYA3 ATP1B1 CSNK1G3 PPIP5K2 PRTG C6orf62 GOLGA8B TRIM13 TSC22D2 RAD21 FNDC3A PNRC2 ATP8B5P CPNE2 ROBO2 RAB11FIP2 SIRT1 NR4A3	down	***
GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP	0.0000241	0.0005854	0.5756103	-0.3239407	-1.722386	175	EPAS1 CD101 OSBPL1A HHEX FABP4 CLEC3B CAT LY86 CLEC10A TBC1D2 CD9 AVPI1 TXNIP DPEP2 PCYOX1 GRN CYB5D2 APOC1 SORBS3 FABP5 CFD PPT1 CPVL SLC7A8 ZADH2 CEBPA KLF7 LINC00324 CADM1 NR1D2 CD302 BACE1 CD300LB MAPRE2 CNRIP1 RPS6KA2 PDK4 SPIN1 CCNY SGK1 SNX29 PABPC4 SIGLEC15 OGFRL1 WDR7 GAS2L3 ECI2 SPOP FAM228B LGALS3 GNA13 PLA2G15 SESN1 HAVCR2 METTL7A ING2 ACADM STARD13 HERPUD1 PHYH CRTAP TREML1 EIF3L TREM2 PLEKHA2 KCNJ1 ATP1B1 HLA-DRB1 ABHD14A METTL25	down	***
GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN	0.0000633	0.0013181	0.5384341	-0.3278989	-1.720958	165	RAB11FIP1 GCOM1 ARHGAP31 OLR1 ZC3H12C LRRC8C SNX10 MIR22HG INSIG1 TMEM170B HCAR2 CALCRL ATF7IP2 SIRPA NDEL1 NODAL PTPN12 REST PLEKHM3 ZFAND5 VASP KLF7 NFKB1 IRAK2 AQP4 CCL4 DUSP1 PLEK SH2D2A N4BP1 PIK3R5 KPNA3 MAFF RASGEF1B FAM102B SOCS3 MITF CPEB4 NXPE3 FOXN2 WTAP MALT1 REL EHD1 CRY1 PDE4B ETS2 ICAM1 CEBPD NLRP3 MEX3C NFKBIA KIT ZDHHC5 TNFSF9 SAMSN1 GSPT1	down	**
GO_DEOXYRIBONUCLEASE_ACTIVITY	0.0040597	0.0366017	0.4070179	0.4541548	1.720753	52	POLE RBBP8 NME1 EXO1 EME1 EME2 XRCC1 DNA2 FEN1 DCLRE1C MBD4 RAD9A POLD1 SLX4 DNASE1 RAD50 MGME1 ZRANB3 APEX1 RAD1 MUS81 DNASE1L2 DFFB RAG1 DCLRE1B DCLRE1A	up	*
GO_RESPONSE_TO_ESTROGEN	0.0017426	0.0192207	0.4550599	-0.3900599	-1.720510	59	SMAD6 ZNF366 HMOX1 TEK PPARG CAV1 CITED2 SFR1 TGFBR2 ARSB SERPINB9 ASH2L GATA3 SFRP1	down	*
MIR518D_5P_MIR518F_5P_MIR520C_5P_MIR526A_5P	0.0008739	0.0114654	0.4772708	-0.3791526	-1.720490	71	SEMA6A TMEM170B JPH4 MED4 NR3C1 NCEH1 ECHDC1 LCP1 TFRC FLI1 HMGN1 PTPN21 ZSWIM6 CLK4 SLC25A33 CREBRF PLGLB1 NXPE3 CHORDC1 SAV1 ZCCHC10 EWSR1 RELL1	down	*
KEGG_ADHERENS_JUNCTION	0.0022035	0.0231021	0.4317077	-0.3877982	-1.720362	61	PTPRB FYN BAIAP2 CDC42 TGFBR2 RHOA PTPRM NLK TCF7L2 SNAI1 SORBS1 TJP1 WASF3 WASF2 RAC2 ACTN2 CSNK2A2 TCF7L1 SMAD2 ACTB CREBBP FGFR1 IQGAP1 SMAD4 MAPK1 LMO7 EP300	down	*
GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN	0.0000157	0.0004100	0.5756103	-0.3234560	-1.719980	176	DENND5A RAPGEF2 CCRL2 MYD88 CIR1 RBM14 ALAS1 CDC42 MARCO BCL2A1 RFTN1 PLA2G7 DNAJC3 HBEGF CYB5A LITAF LCP1 STOM PDE4D TFRC TXN CASP5 MAP2K3 PLAUR DENND3 GMPR CCL3 RIT1 ATF3 DUSP1 INHBA VAMP5 N4BP1 CRIM1 FLT1 OASL CD48 SH3BP5 DNAJA1 RCAN1 PPP1R15A WTAP CCR7 IFRD1 CD83 CXCL5 PPP2CB TESK2 DUSP5 PIM1 KYNU ANKRD12 GEM ICAM1 SLC31A1 NBN	down	***
GO_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	0.0000000	0.0000000	0.9436322	-0.2742653	-1.719885	871	TNR FFAR4 SIGLEC11 SEMA6B AJAP1 SEMA3G GPR17 NLRC4 SEMA6A EREG ACP5 CD300LF IL17RB SASH1 FOXF1 SWAP70 FCN1 TEK EDNRB SCIMP SIGLEC16 PPARG ADTRP CD55 PGC WFDC1 IL1B FABP4 MNDA WNT4 THBD CDH5 FYN LPL LY86 SAMHD1 CLEC12B CAV1 CALCRL CDH13 MYD88 BMPR2 TBXA2R C5AR1 CLEC10A RBM14 S1PR1 HMGCR FGF10 MARCO CASP12 IL1RL1 CD9 GAS6 OTUD4 PSMD5 LAMP1 TGFBR2 SCARF1 TRIB1 RFTN1 IL23A FGR DNASE1L3 PDE2A APOD SEMA6D CD36 ANXA1 MIR146A MYOZ1 PLA2G7 SH2B3 CARD16 SEMA3B ADA FOXA2 ADAM17 CLEC7A TNIP3 HSPB1 ANXA5 RNF125 FOXP1 IFNK SERPINB9 GATA3 JAM3 SIRPA PLXNA4 RB1 TRAF6 NFE2L2 NDEL1 GRN CRK CRTAM WNT3A KANK2 UBE2D3 PDGFA CASP5 SLC7A2 IL10 DUSP3 BIRC2 PTPRO MEFV CASP1 BST1 SLC46A2 ZSWIM6 KLF4 PLAUR THBS1 CEBPA STX3 SOCS5 LY96 UBQLN1 CCL3 NFKB1 CDKN1A CADM1 NR1D2 PTPRC IRAK2 SELP HPSE CCL4 TLR4 PTGER3 SFTPD XCL2 FCER1G PER1 DUSP1 PLEK ZMPSTE24 OXSR1 UBASH3B PTGIS BACE1 AKIRIN1 KREMEN1 PIAS1 STK24 HCK NCKAP1L IL17D CNTF METAP1 IL6 MUC3A PDE6A CD160 CTSS PDE6B SOCS3 APPL1 SEC14L1 PSMA1 NOTCH1 ETS1 RAC2 CARD8 HSPA1B IFNGR1 JAK1 PTGER4 CCR7 ENPP4 DAPK2 PRKCE GPR183 OSM MALT1 RTN4R UNC13B PRKACA SUCNR1 CST7 PPM1F CD34 PLCG2 UBB PELI1 BCL6B CALM1 YTHDF3 PSMD12 ICAM2 PRKCG EPPK1 TREX1 CD74 CR1 PIK3AP1 SMPDL3B CCR4 TGFB1 AP1G1 CD1D CD6 TEC FPR2 YTHDF2 NLRP6 PIK3C3 CNOT7 CD81 KLRC4-KLRK1 CCR1 CLASP2 GPR18 GRK4 ADAM10 IFNLR1 SYT11 CCR6 FGF2 IL18 IL18RAP TFPI ARRB2 SEMA4A RTN4 TIAM1 CXCR4 EPHA4 TAB2 RIPK2 NLRP3 UBE2D1 HAVCR2 PSME4 CREBBP GRIN3A ICAM3 TLR10 SIN3A NFKBIA ADORA2A CTSC EDN1 PAK2 KLRK1 PTEN MTUS1 PRKG1 AIM2 FGFR1 RORA ITCH LDLR PSMD6 PSMD9 SFPQ IL16 PUM1	down	***
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP	0.0000344	0.0007919	0.5573322	-0.3239084	-1.719580	174	SC5D FCN1 CD101 HHEX FBP1 DCSTAMP LPXN LIPA TMEM170B SAMHD1 GFOD1 RASAL2 NCF2 CD9 AVPI1 TXNIP CD36 NCEH1 CLEC7A CAMTA1 ABHD6 RGCC SPRY2 PPT1 KIAA0513 ADO KLF9 LAPTM5 PAPSS1 TM6SF1 EVI2A RAP1GDS1 UBASH3B CD300LB PRCP RBPJ PGD MITF MALT1 LPCAT2 VMO1 FOS TGFB1 GABARAPL1 DECR1 GNA13 PLA2G15 ARHGAP18 TBC1D1 SCPEP1 CD1E DOCK10 CAMSAP2 ENY2 HAT1 DISP1 GREM1 SERPINE1 C5AR2	down	***
GCM_PTK2	0.0000609	0.0012766	0.5573322	-0.3408707	-1.719421	131	MGAT3 CLDND1 CCDC88A KIAA1109 PLEKHA1 AGPAT4 EPB41L3 TEX2 ZEB2 DNAJB14 TTL NLK SPIRE1 TTYH2 ABHD6 MOAP1 CCDC82 PEG3 DOCK9 BACE1 FMNL2 GZF1 MAP4K4 FRYL NAA30 OCIAD1 NAPG DDHD2 MTMR2 FAXDC2 PPIG WBP2 NPTN CLASP2 PHLPP2 ARPP19 GLTP RTN4 TMOD2 SIK3 MEGF9 TMEM184B ULK2 CCDC92 FNIP2 KIF1B RNF13 RABGEF1 TMEM30A FAM8A1 DYNC1I2 DIRAS1 KIDINS220	down	**
REACTOME_PEPTIDE_HORMONE_METABOLISM	0.0022296	0.0232639	0.4317077	-0.3996082	-1.719312	54	FFAR4 ACE VAMP2 SPCS3 PLA2G7 ANPEP CES1 TCF7L2 KLF4 BCHE MYRIP CTSD INHBA CTSZ MME CPA3 EXOC1 EXOC2	down	*
GO_RESPONSE_TO_AMINE	0.0030282	0.0293687	0.4317077	0.4865065	1.719195	39	CPS1 PPP1R1B ASIC1 GRIN2A GLDC NME1 ITGA2 ADAMTS13 ASS1 OXTR CAD RGS4 CDK1 RGS17 UROS	up	*
GO_NUCLEOSIDE_METABOLIC_PROCESS	0.0013868	0.0163078	0.4550599	0.4129181	1.719043	87	AK4 PRTFDC1 GMPS UMPS DPYS NME1 DNPH1 DLG1 CARD11 NT5C1B NME9 NME5 AHCY CAD LRGUK UCK2 ATIC OARD1 UCKL1 UPP2 DHODH TK1 DTYMK NT5M APOBEC2 NME4 NME7 GMPR2 TK2 APOBEC3B DGUOK DPYD APRT OPA1 PRPSAP2 TYMP	up	*
GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP	0.0000473	0.0010321	0.5573322	-0.3275387	-1.719018	167	KLF13 HSD17B11 KIAA1109 INPP5A NEDD9 AGTPBP1 FRAT1 IER2 TOE1 TNFRSF8 KLF6 CD93 CLK1 EPM2AIP1 MCL1 CFD SRSF5 SAP30BP CASP1 KLF4 CPVL DENND3 PTPRC SELL CLK4 DUSP1 WDR48 EVI2A S1PR4 NXF1 JUNB CSTA PPM1F PELI1 KLF2 ICAM2 ING3 CD1D CBFA2T3 RGS2 HELZ SEMA4A CEBPD SIK3 NLRP3 ICAM3 FNBP4 LYST DAZAP2 IL16 MIS18BP1 SETX DUSP6 CX3CR1 CRBN ING1 ZFP36 MTSS1 DAPP1 SECISBP2 DUSP22 JARID2 ARGLU1 MYO1F CRLF3 TNFRSF1B IL10RA PNISR PELI2 C15orf39 SYF2 VNN2 STK10	down	**
GO_MEIOTIC_CELL_CYCLE_CHECKPOINT	0.0040979	0.0368295	0.4070179	0.7754199	1.718778	7	TRIP13 TTK NSUN2 HORMAD1	up	*
GO_CYTOKINE_RECEPTOR_BINDING	0.0000340	0.0007851	0.5573322	-0.3230976	-1.718418	184	SMAD6 CXCL3 CD300LF IL1A CXCL16 IL1B BMP2 CDH5 ENG CCL3L1 CCRL2 MYD88 TGFBR3 IL1RN TGFBR2 IL23A SH2B3 CLCF1 ADAM17 LIFR ITGA5 IFNK GATA3 TRAF6 NODAL IL10 CCL22 SDCBP TNFSF12 TNFSF15 SOCS2 TMBIM1 CCL3 CXCL2 CCL4 XCL2 SMAD7 INHBA TGFB2 CNTF IL6 BMP3 JAK1 PIK3R1 GRB2 OSM CXCL5	down	***
GSE3982_EOSINOPHIL_VS_TH1_DN	0.0000758	0.0015301	0.5384341	0.3798222	1.718392	173	FOXM1 CEP72 RUVBL1 ELOVL6 APOLD1 METTL1 PTTG1 TYMS CAND1 SHMT2 CCT2 NME1 LDHB KNTC1 EEF1E1 PUS7 APOL1 VANGL1 ZNHIT6 ABCB6 KDELR2 PHB TST ERCC2 CNPY2 PLOD2 ASF1B BIRC5 AAGAB GOLGA8A MRPL17 NEIL3 SPAG5 METTL3 PA2G4 RNASEH2A RANGAP1 SNRNP25 DNMT1 DNAJA3 ATP9A DPH2 GINS2 MRPL4 AGPAT5 KIF20B DAP3 ASNS COPS6 FN3KRP PFAS BAD MRPL24 UBE2V2 MRPS33	up	**
GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_DN	0.0000456	0.0010049	0.5573322	-0.3241361	-1.718097	181	ACP5 RAMP3 SWAP70 HVCN1 GPR65 CALCRL IDI1 SLC15A3 GIMAP6 AGPAT4 EDEM1 CLCF1 HBEGF SBDS SGMS2 ADAM17 MAP3K8 KLF10 NFE2L2 TUBB6 SLC7A2 IL10 RAB12 REST PNRC1 N4BP1 MAPRE2 PROCR RPS6KA2 RNF149 SYNPO2 SOCS3 OASL ARL5B ST6GALNAC4 HSPA1B JUNB ATP11A EEA1 GPR183 DENND4A CDK17 UBXN2A VAV3 TGIF1 DUSP5 IFNAR1 STK40 GNA13 PLEKHO2 GTF2B RNF2 CTTNBP2NL SETDB2 IQSEC1 RIPK2 RASSF8 ADORA2A KIT NRP2 SPATA13 PAPSS2 CSF2 SUGT1 CD70 CDC14A CX3CR1 OSGIN2 HLA-DRB1 DAPP1 UBE2N RCSD1 CSF3 SH3BP2 PDPN NR4A3 NCOA7 EBI3 ST3GAL1 TNFRSF1B SLAMF7	down	**
REACTOME_KERATINIZATION	0.0030818	0.0297758	0.4317077	0.4860781	1.717681	39	PCSK6 LIPM KRT5 PKP2 PKP1 KRT16 KRT15 FLG TGM1 PERP KRT18 ST14 PKP3 PKP4 KRT19 KRT8 SPINK5 KRTAP5-9 PRSS8	up	*
GO_LYSOSOMAL_LUMEN	0.0009355	0.0120571	0.4772708	-0.3686057	-1.717030	78	LIPA GPC5 MANBA FUCA1 HSPG2 MAN2B1 ARSB ASAH1 NAAA GM2A IFI30 PRELP PPT1 GAA TPP1 CTSD HPSE GLB1 HEXB CTSS	down	*
GO_ASTROCYTE_DIFFERENTIATION	0.0010699	0.0133921	0.4550599	-0.3791189	-1.717018	67	DAB1 TAL1 IL1B BMP2 C5AR1 CLCF1 GRN LAMC3 VIM ID2 TLR4 HES1 ID4 CNTF IL6 PSEN1 LAMB2 C1QA NOTCH1 IFNGR1 GPR37L1 FPR2 EPHA4 ADORA2A LDLR MAPK1 TREM2 S100A8 NOG	down	*
GSE3982_EOSINOPHIL_VS_TH2_DN	0.0001732	0.0030462	0.5188481	0.3782965	1.716549	176	RIBC2 RUVBL1 CDC45 FAT2 COIL APOLD1 KIF18B PLK1 PTTG1 CCT6A COX11 CCT2 DNPH1 DLG1 SMARCC1 AUNIP PUS7 NDUFS2 TMEM177 P4HTM VANGL1 MPHOSPH9 GPSM2 ACTL6A FBL PERP CAD PHB CNPY2 CMAS NUSAP1 BIRC5 NCAPG CPNE1 NUP205 MRPS12 PA2G4 RANGAP1 DNMT1 FANCG ATP6V0E2 DPH2 IL15RA MRPL4 KIF20B SPA17 AAMP PFAS BAD LSM7 NEK4 TBC1D16 LSM4 MAB21L1 PRMT5 CCNA2 NFRKB SNRPD2 RNF123 NDUFA8 DNAJC10 DHRS3 MRPS27 PWP1 ENO1	up	**
GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN	0.0000364	0.0008273	0.5573322	-0.3233149	-1.716430	174	OSBPL11 PRKG2 SNX10 ENG KL PRPF38A PDCL RBM7 PCYOX1 IFI30 ANXA5 ZEB1 TMEM38B ATP10A TIMM10B BNIP2 AGR3 ARC PNRC1 N4BP2L1 PPP2R5A RABGGTB MCMBP DDHD1 HSD17B13 PGD PLEKHA3 ETV3 NOTCH1 DDX17 APBB2 SNX2 IRF8 NAA30 TPRA1 MOB1A MBP EMC7 STXBP3 PARD6A NAB1 GALC WBP2 CTTNBP2NL MGAT2 IQSEC1 CXCR4 RIPK2 G3BP2 KATNA1 FNBP4 KLRK1 SKI THRAP3 C1orf52 ZFAND2A UBXN8 CHIC2 CLEC4E PRKCH TRMT1L DRAM2 KMT2E RNF167 GNG11 SNX14 CAPZA1	down	***
KEGG_CHEMOKINE_SIGNALING_PATHWAY	0.0000863	0.0017033	0.5384341	-0.3334471	-1.716223	151	CXCL3 CXCL16 ADCY9 ADCY4 CCL3L1 ELMO1 CDC42 FGR RHOA RAP1A GNGT2 GNG7 CRK AKT3 ROCK2 ARRB1 CCL22 ROCK1 GRK5 CCL3 NFKB1 CXCL2 SHC4 CCL4 XCL2 PIK3R5 GNAI2 HCK ADCY2 RAC2 CCR7 PIK3R1 GRB2 PRKACA CXCL5 FOXO3 CCR4 VAV3 GNAI1 GNG5 GNB4 CCR1 GRK4 CCL20 CCR6 ARRB2 TIAM1 CXCR4 CCR9 NFKBIA	down	**
ZNF532_TARGET_GENES	0.0024835	0.0252816	0.4317077	0.4458224	1.716120	55	EGLN3 CDCA7 HOXB7 DZANK1 C19orf48 WASF1 RPL32P3 NSUN2 PES1 NUP205 TAF6 SRD5A1 SUDS3 NUP85 RNF187 BLCAP GOSR2 DTNB FARSB SMC2	up	*
WHITFIELD_CELL_CYCLE_G2_M	0.0000930	0.0018184	0.5384341	0.3767241	1.715755	180	TRIP13 FOXM1 FGA BUB1B NEK2 CCNB1 CENPF PBK DEPDC1 TFF3 DEPDC1B TTK GTSE1 KIF14 ANLN TOMM34 PLK1 NUF2 CENPA ECT2 TPX2 CCNB2 MCM4 ASPHD2 SPDL1 HMMR CEP55 MKI67 BUB1 IDO1 AURKA VANGL1 ODF2 KIF2C C6 POC1A GPSM2 CDC42EP1 KNSTRN CKS1B HPS4 NUSAP1 BIRC5 KLHDC9 PSMG3 SPAG5 SAPCD2 SRD5A1 RANGAP1 DLGAP5 MAPK13 ANP32E KIF20B	up	**
GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN	0.0000310	0.0007244	0.5573322	0.3755868	1.715684	185	UCHL1 PRIM2 BRCA1 NDUFS6 IFT27 ACAD9 MCM2 XPNPEP1 XPOT TAMM41 CISD1 KIF23 MKI67 BUB1 TOP2A POLD2 GCAT CHAF1B LMNB1 AIMP2 FAM162A LIG1 ORC6 MAD2L1 RAD51AP1 DCTPP1 CAD CNPY2 INCENP CKS1B NUSAP1 CDK1 BIRC5 GMNN ZMIZ2 POLR3K MRPL17 TSPAN31 EZH2 ETFB SNRNP25 DNMT1 MZT2B TUBG1 TACC3 MNS1 MBD4 TRIM37 NUP85 MARCKSL1 RAD50 CENPK CKAP5 CDC20 CKAP2 MCM5 RCC1 HAUS4 MARCKS GADD45G NDUFV1 RFC5 NME4 INO80E HK2 TRAK1 PGAM1 RPN1 CHERP DTD2 NCAPH CYB5B RNF14 UNC119 RCN2 MRTO4	up	***
PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN	0.0001562	0.0027873	0.5188481	-0.3402809	-1.715641	128	TMEM100 SECISBP2L CD44 PLEKHF2 TGFBR3 TRIB1 CCNL1 ARHGAP29 ECHDC1 ZNF410 KLF6 NDEL1 HNRNPDL LAMTOR3 BAG1 EPB41L2 MTMR6 ID2 DUSP1 EXOSC8 N4BP1 TP53BP2 NRBF2 RABGGTB ZNF330 MOB4 RYBP DCTN6 RBM34 TRAK2 CEBPZ ZBED5 ING3 BCAS2 TEX30 ZCCHC10 CCNH CCL20 AMD1 TNFAIP8 CGRRF1 CDC42EP3 GTPBP8 LDLR C1orf115 HAT1 SH3GLB1 HEY1 ANKHD1 CDK7 WWTR1 TAF1D ORC4 AIMP1 RAB11FIP2 PTGS2 BTBD1 NOL11 IVNS1ABP ARFGAP2 UQCRB LEPROT	down	**
GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP	0.0000377	0.0008551	0.5573322	-0.3240792	-1.715198	169	CLEC1B HSPB7 OLR1 TUBB1 SH2D3C LDB2 STX11 ALAS1 NEDD9 IL23A CCNL1 SGMS2 HECW2 ENTPD1 KLF10 SLC7A11 SLC25A37 SPRY2 ITSN2 PTPN12 SNED1 SORBS1 BST1 USP2 FMNL3 UBE2B CD53 PLEK N4BP1 RASGEF1B PIAS1 BTG1 NINJ1 MYLIP ATP6V0B CNTN4 SKIL MPZL3 ZNF597 ACSL1 PELI1 PRKCG PIK3AP1 NAB1 PIM1 TAGAP XKR8 IQSEC1 SIK3 SSH2 GRIN3A LYSMD3 MTUS1	down	***
GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN	0.0000380	0.0008597	0.5573322	-0.3230696	-1.715127	174	GLIPR2 DPYSL2 RGS9 CALCRL OTUD4 USP47 CCNL1 RBM7 FAM89A ZNF503 DACH1 FAM122A ZFYVE16 TXN ATP10A PLAUR OSTF1 THBS1 ST7L GPR85 PAPSS1 CLK4 WDR48 NUS1 EFR3A KREMEN1 PIAS1 TDRD7 USP25 UFM1 CD80 PPP2CA INO80C NXF1 GABPA ATP6V0B GMFG MORC3 TPP2 TMEM128 MAPK8 SPOP EMC7 AZIN1 ZBTB1 KCTD10 TSC22D1 FEM1B YTHDF2 CNOT7 HNRNPH3 GEM EPHA4 ARL14EP TBC1D1 LYSMD3 NFKBIA KLRK1 COL13A1 PPP1CB PIM3 CFL2 BHLHE41 TBPL1 SPPL2A	down	***
LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER	0.0000282	0.0006663	0.5756103	0.3713808	1.714665	200	PAX9 PDCD6 CCDC127 TSFM METTL1 CDK4 NDUFS6 FIGNL1 COCH TDRKH CCT6A CLCN2 ZNF3 MAGEF1 CLPTM1L KCNH2 NUDT1 ZNF74 SDHA CCT5 NDUFS2 YKT6 MCM7 ABCC5 SETDB1 SLC12A7 EGFR PARD3 MIPOL1 CKS1B MRPL36 FASTK HDGF SEC61G TAF6 FADD DAP SRD5A1 POLR2H ILF2 ZSCAN21 DPP3 DVL3 MRPL11 DUSP12 ADAR SLC4A2 S100A13 JTB COPS6 TSTA3 PLD1 ALKBH4 PPP1R3D POLR2J BLCAP USP21 C5orf22 LANCL2 PYGO2 HAX1 PIP5K1A PSMB4 PI4KA FKBP9 MANBAL ABCF2 ARHGAP5 MRPL9 CDK5 EIF4G1 PNN SLC39A1 PI4KB NAT10 PPP1R16A CORO1B GEMIN2 POGZ INPPL1 MED15 LPCAT1 FASTKD3 OPA1 CCS PMVK PRCC	up	***
GSE17721_12H_VS_24H_LPS_BMDC_UP	0.0000269	0.0006408	0.5756103	-0.3223698	-1.714034	175	SGK3 ZC3H12C PRKG2 TMOD3 MYD88 PRPF38A MKNK1 FGR CCNL1 KCNAB1 ABCG2 KLF10 KLF6 PPP2R2A ARHGEF2 ITSN2 KIF1C CCL22 RAB12 BNIP2 DENND6A SLC7A8 VRK2 RBMS1 UBE2E2 PTPRC GPR85 ATF3 ELAC1 PLEK SPRYD7 FKBP15 MAPRE2 NRROS RPS6KA2 IL6 NEK7 NXF1 SERPINB6 MORC3 PXK SLC3A2 SAV1 GPR84 APLP2 PDLIM5 WDR1 ALDH1B1 IER5 PLGRKT KATNA1 NFKBIA	down	***
GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN	0.0000352	0.0008071	0.5573322	-0.3222154	-1.713726	184	TMEM126A U2AF1 RCOR1 ST3GAL6 GTF2E2 PRPF38A NEDD9 BCL2A1 CD9 PTS ASAH1 LITAF CYP4V2 AHNAK CASP1 YBX3 RRM2B ITIH5 NFKB1 ID2 ARAP3 EVI2A CPT1A KLRD1 TM9SF2 IL7R MAPRE2 CREBRF CD160 KCTD12 TYROBP SHOC2 GSTO1 EEA1 DAPK2 CREB1 RAB8A SNX1 CST7 OCIAD1 SNX9 GRSF1 RHOQ CHPT1 TCF4 TGIF1 PDS5B VAMP4 TSC22D1 GABARAPL1 ACADL DECR1 RGS2 ARPP19 TFPI OSER1 KIT B3GNT2 CHCHD7 MCOLN2 DAZAP2 RHOT1 GIMAP4 EID1 KLC1 HERPUD1 PHYH	down	***
GO_HEART_VALVE_DEVELOPMENT	0.0025103	0.0254939	0.4317077	-0.3982432	-1.713440	54	SMAD6 BMP2 BMPR2 TGFBR2 PDE2A GATA3 RB1 ROCK2 SNAI1 ROCK1 ADAMTS9 TBX5 DCHS1 TGFB2 RBPJ NOTCH1	down	*
MIR935	0.0006799	0.0094354	0.4772708	-0.3546213	-1.713328	95	OSBPL11 PRKG2 LMO2 P2RY13 CLEC14A FOXJ3 ZNF365 GMEB1 TBC1D9 FOXO1 MYO1B CRIM1 SPIN1 GABARAPL2 GLUD1 ATXN1L EEA1 GFPT2 ZFAND6 KIAA0232 IRS2 LEKR1 PGGT1B HACE1 TNFAIP8 INO80 PUS10 SCAI RORA NRG1 KALRN CSNK1G3 MTSS1 CSF3 SREK1IP1 JARID2 NCOA7 ERLIN2 IREB2 ANKRD44	down	**
GSE9988_LPS_VS_LOW_LPS_MONOCYTE_UP	0.0003806	0.0059467	0.4984931	0.3961313	1.713159	120	STYK1 FANCI DEPTOR MPP6 ZNF138 E2F8 PCDHGB6 IGSF11 CDCA8 LAMP5 GLDC LRRC31 PCDHGB8P ZNF485 HHIP-AS1 WDR78 TTC22 SDHAP1 TRMT61B KLHL3 FBXO16 C12orf75 GABRB2 TRAP1 ZNF789 DIAPH3 SEMA4F AMPH DHRS4-AS1 PKP3 ZNF544 GBP6 HMGB3P22 ZNF320 PTHLH STRBP ME1 TMEM72 PARG CGN ZNF204P SLC38A4 TLR5 SLC1A7 MED22 WDR63 PLK4	up	**
GSE41867_DAY8_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP	0.0004025	0.0061948	0.4984931	0.3980787	1.712551	117	PRR15 MYBPH ABCA17P PHGDH LYPD6B ANKRD24 FBXL19-AS1 DZANK1 ZNF607 GPR37 NLE1 SMAGP TIGD4 FBF1 SLC4A11 CHAF1B RNFT2 ARHGEF34P SCAMP5 LRRC61 BLM PARD3 LAMB4 RNF207 CXCL17 LINC00173 TBX1 CADM4 ITFG2 DLK2 LCN12 RHD CHADL CHRD COL26A1 NSUN6 CEP152 ALMS1 TMC5 ZNF70 ACKR2 ZFP14 PTPRF BCAS3 SH3GL1P2 ZSCAN20 SNAP25 TMEM132B INO80B ANO8 DNAAF1 DNM1P46 SMYD3 AMH THY1 GDF11 CEACAM19	up	**
MODULE_18	0.0000002	0.0000095	0.6901325	0.3519679	1.712536	381	RIBC2 TRIP13 PLAT FOXM1 PAX9 TFAP2A BUB1B CCNB1 IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 GTSE1 GMPS SPP1 BAMBI MMP1 TOMM34 PLK1 AURKB CENPA PTTG1 TBX19 ESPL1 TPX2 RBBP8 MCM2 TYMS ORC1 CCNF CCT6A SHMT2 ZWINT INTS1 TNC CEP250 CASP2 NUDT1 CHAF1A PRB4 EEF1E1 TOP2A CBX3 MYO10 CARD10 POLA2 MCM7 MSX1 TTLL12 PRKDC SLC22A18AS MRPL3 KIF11 LMNB1 AIMP2 CDC42EP1 MAD2L1 SCAMP5 AHCY PSMD4 PKMYT1 CAD FDXR PPP5C CLDN9 TMED3 CDKN2C TMEM106C PLOD2 KRT18 CDK1 SSBP1 FAT1 UCK2 ARPC1A TNFRSF25 E2F1 UNG TRIM2 PEG10 FEN1 NUP205 FADD IGSF3 CBX1 PSMC4 ITGA2B ITPR3 TBX1 DNMT1 LGR5 VBP1 DLGAP5 TRIM16 SLC26A2 CHST3 LMNB2 TK1 DTYMK ASNS SLC4A2 FHL2 TWF1 TYRO3 MAT1A CKAP5 CDC20 IARS2 ERBB3 RPA1 CXCL1 MCM6 RCC1 WDR45B PDIA4 SLC1A5 LSM4 MCRS1 RPS26 CCNA2 CAP2 FKBP9 ACKR2 DLEC1 LPGAT1 TRIP6 HOXB2 CIAPIN1 TRIB2 MTHFD1 DHRS3 PAICS APEX1 SNRPC UBE2C PWP1 NUP93 WIZ CALU IFI16 NQO1 CYB5B TPM1 APOBEC3B MLLT11 RCN2	up	***
GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_DN	0.0002100	0.0035755	0.5188481	-0.3390387	-1.712211	129	RAB11FIP1 ZC3H12C MIR22HG GFOD1 B3GNT5 NR4A1 CLK1 MAPK8IP1 RHOB CSRNP1 IRAK2 ZBTB43 CLK4 TP53BP2 SLC25A33 CREBRF HCAR3 AREG CREM DNAJC27 ETV3 PTGER4 OSM KBTBD8 GRASP MFAP4 HOMER1 DENND4A PELI1 FOXO3 TGIF1 IRS2 RIMKLB RGS2 PDE4B GEM ABL2 MIR155HG DDX59 TMEM217 TRAF1 TTC32 FNBP4 MAFK ZNF165 PURB PMAIP1 DCUN1D2 PIM3 NR4A2 SLC19A2 EFNB2 PATL2 DNAJB1 TPSD1 IRF1 SIRT1 NR4A3 PTGS2 METRNL IVNS1ABP ZCCHC14	down	**
REACTOME_M_PHASE	0.0000016	0.0000558	0.6435518	0.3569685	1.712101	317	CEP72 KIF20A BUB1B NUP107 NEK2 CCNB1 CENPF NDC80 TUBB2B CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CCNB2 PRKCA DYNC1I1 NCAPD2 ZWINT DCTN2 SPDL1 HAUS5 CEP250 KIF23 KNTC1 BUB1 CENPL NUP155 ODF2 SFI1 TPR KIF2C MAD1L1 LPIN3 CDCA5 LMNB1 MAD2L1 PSMD4 CENPO SPC24 INCENP NCAPG2 ANAPC5 CDK1 CENPJ CENPH BIRC5 NCAPG PSMB5 KIF2A ANAPC7 NUP205 DYNLL2 PSMC4 CENPP FGFR1OP KPNB1 RANGAP1 MZT2A MZT2B CEP63 CEP192 CDC23 TUBG1 PSMA5 NINL TUBB2A PSME2 TUBA3D TUBA8 CENPQ ANAPC1 PSMD2 NUP85 CENPK CKAP5 PSMB3 CDC20 CENPM TUBG2 AAAS CHMP4C CDK5RAP2 DYNC1LI2 CENPT HAUS6 RCC1 HAUS4 PSMB4 CEP152 NUP62 ALMS1 BANF1 ANAPC2 TUBGCP4 CEP164 LPIN1 TUBA4B ZWILCH SEC13 NME7 CHMP2A SMC2 MAU2 CENPE GOLGA2 LEMD2 UBE2C NCAPD3 TUBA1C PPP2R5D NUP210 CLASP1 NUP93 NCAPH CEP290 CHMP6 DYNC1H1 PLK4 AKAP9 PCNT DSN1 PPP2R5E FBXO5 PSMB10 TUBGCP2 PSME1 NSL1 TMPO	up	***
GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN	0.0002107	0.0035798	0.5188481	-0.3382576	-1.712049	138	FCN1 BAG4 FLVCR2 IL1RN CD36 CD33 ENTPD1 EIF1 ADIPOR1 SLC25A37 CD93 GRN SPI1 ZMIZ1 CYBRD1 PTGIR DUSP3 PPT1 SDCBP BST1 KLF4 PLAUR TPP1 PLBD1 CTBS CD302 PLEK GNAQ VAMP3 CTSS PGD SOCS3 SERPINB8 IFNGR1 GRB2 DEDD ACSL1 FOS SORT1 TIMP2 SERPINB1 APLP2 LGALS3 CTIF STX12 TSPO BNIP3L GPX3 CHMP3 MS4A4A GLUL DAZAP2 WDFY3 EGR1 CSF2RB CRTAP ZYX S100A8 FPR1 QSOX1 CYP51A1 TRIM25 RAB1A CCPG1 RNF19B CYP1B1 MYL9 GSN HBS1L	down	**
GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY	0.0002983	0.0048626	0.4984931	-0.3399375	-1.711868	120	RASIP1 HHEX IL1B INPP5K CAV1 HMGCR PRKAR1A HEG1 SH2B3 FBXO7 LATS2 HSPB1 HIPK3 PAQR3 RB1 SFRP1 SPRY2 MAPK8IP1 DUSP3 CEBPA CDKN1A MIR24-2 DUSP1 PKIG PPP2CA DNAJA1 DUSP8 IPO7 SPRY4 PKIA CHORDC1 DUSP5 MYOCD RGS2 KAT2B PP2D1 CDKN1C IPO5 PTEN DUSP7 SMPD1 CDKN1B DUSP6	down	**
GOLDRATH_IMMUNE_MEMORY	0.0025047	0.0254525	0.4317077	-0.3864129	-1.711865	60	CD55 CTSW AQP9 ABCB1 PRSS12 CYP4V2 SORBS1 RRM2B PDE8A DOCK9 NR1D2 RECK PLCD1 CD160 KCTD12 PRKCE RRAS CHPT1 FCGRT RNF138 TRAF1 PALD1 CHCHD7 MCOLN2 USP48 HCFC1R1	down	*
REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS	0.0051293	0.0436709	0.4070179	0.5868802	1.711863	19	MUC5B MUC13 MUC4 MUC16 MUC5AC MUC20 MUC6	up	*
PSMB5_TARGET_GENES	0.0000050	0.0001561	0.6105269	-0.3151716	-1.711816	221	ABHD5 TSPAN4 SNORD101 CD44 CITED2 TMEM138 SRSF7 SNORD12C CCNL1 SNHG5 ZBTB4 MALAT1 LMNA PPP1R15B EIF1 BTG2 CYB561A3 SRSF2 TOB1-AS1 MCL1 SNHG1 RHOB AHNAK RNU11 THBS1 ATF3 ID2 DUSP1 MFSD11 CALM2 AFF1 RABGGTB ZCWPW1 SLC25A3 ID4 SGK1 SRSF3 NXF1 CYCS HSPA1B JUNB DNAJA1 PPP1R15A DDX5 RNVU1-14 SLC3A2 UBB KLF2 CALM1 PXN-AS1 SRSF6 HNRNPA2B1 ZFAS1 SNORA57 TOB1 GTF2B INTS6 WDR1 ADAMTS4 IER5 RNU4ATAC HSP90AA1 TOB2 HSPA8 ACTB NABP1 EIF4A2 ATF4 PMAIP1 SLFN11 HNRNPH1 PRKG1-AS1 SERPINE1 FUS GAS5 FTL SLC38A2 ARL4D ZFP36 TUBA1A MT1E CALR POLR2L C6orf62 SNHG9 TRIM25 NDUFAF3 NFKBIZ SNORA9 KBTBD2 MEPCE EMP1 CEP95 PNP ANO10 VASN PIK3R3 TUBB3 MAT2A ADAMTS1 UBC ID1 EEF1A1	down	***
GO_PHOSPHOTRANSFERASE_ACTIVITY_PHOSPHATE_GROUP_AS_ACCEPTOR	0.0052946	0.0446259	0.4070179	0.4860488	1.711305	38	AK4 PPIP5K1 IP6K3 AK8 NME1 DLG1 CARD11 NME9 NME5 LRGUK AK7 DTYMK IP6K2 RAD50 ATP6AP1 NME4 NME7 PNKP	up	*
GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP	0.0000308	0.0007202	0.5573322	-0.3214550	-1.710831	177	SEMA6B SWAP70 OLR1 PHACTR1 PPP4R1 CD9 HEG1 PDE2A SH2B3 LMNA PKD2L2 EIF1 SERINC1 AKT3 SPTBN1 TLE4 AGO3 SAP30BP CADM1 TAF9 IL7R PAFAH1B1 AKIRIN1 CDKN2AIP MMP19 TDRD7 EMP3 SAR1A ESD RAB8B RHOG FERMT2 PODXL UNC13B RNF24 YWHAZ CGGBP1 TPRA1 AMD1 MOB3B OPN3 B3GALNT1 SNX15 ITCH NRP2 IQGAP1 SFPQ GSPT1 PAPSS2 HTRA2 SSB ZNF654 DNAJC8 KIDINS220 GABPB1 ACTR1A EP300 TRIM25 SH3BP2 UEVLD MPDZ KRT10 HS3ST2 CYP1B1 APOBR CBLL1 MFHAS1 PPP2R5B TRNAU1AP BCAP29 TOP1 PLEKHM2 S100A10 CDC27 IL1R1 VEZF1 SLC25A44	down	***
GSE17721_0.5H_VS_8H_CPG_BMDC_DN	0.0000348	0.0007989	0.5573322	-0.3232297	-1.710635	172	SASH1 MS4A7 DENND5A C18orf32 NUP54 OSCAR CAV1 IDI1 PRPF38A DSCAML1 PILRA ABCB1 RBM7 ANXA1 SERINC1 COX18 ZBTB21 TOR1AIP1 CLK1 ZEB1 CASP1 SLC7A8 RMDN3 CLIC4 ELK3 MBD2 MPC1 MTPN MOB4 ARL6IP6 TREM1 DNAJA1 ENPP4 LYRM1 PRKCE CREB1 REL PHOSPHO2 PSMD12 CCR4 UBXN2A HBP1 ICAM1 ARAP2 SLC31A1 SFT2D1 EPHA4 ARL14EP TBC1D1 KPNA4 TLK2 THEMIS2 PPP2R3C SERPINE1 TNFSF8 CLIP1 SLC38A2 FAM8A1 DRAM2 DYNC1I2 EYA3	down	***
GO_CILIUM_OR_FLAGELLUM_DEPENDENT_CELL_MOTILITY	0.0035020	0.0329772	0.4317077	0.4263422	1.710374	68	DNAH2 SORD SLC26A8 DNAH3 DNAI1 SPAG16 DPCD TEKT2 PLTP WDR66 DNAH8 GAS8 DNAH11 CCDC40 DRC1 LRRC6 DNAH5 TCTE1 CATSPER3 DNAH7 IQCG TEKT3 TAC4 ROPN1B EFHC1 CATSPER2 RSPH4A CATSPER1 DNAH1 TACR1 ARMC2 TEKT1 WDR63 ROPN1L	up	*
MIR4671_3P	0.0000559	0.0011825	0.5573322	-0.3224108	-1.709904	182	DLC1 PPARG SECISBP2L CPEB2 DDX6 FOSL1 MTMR10 TSHZ1 TRIB1 ZBTB4 WNT2B RAP1A SRSF2 AGO4 RAB12 DGKE NPNT SOCS5 KLF7 ERP44 ARHGEF26 PNRC1 SLC6A6 PAFAH1B1 PIK3R5 MARK3 IKZF5 CNOT6L AFF3 GPBP1 CCNY TMOD1 PDIK1L APPL1 HCFC2 EPC1 FERMT2 SNX2 STX7 PSTPIP2 KBTBD8 ZNRF3 ACSL1 UBB PELI1 HIVEP2 RUNX3 NIPA2 SBF2 TOB1 SERINC3 CEP170 EPN2 RAB5A LRP12 TOB2 CYP2U1 ULK2 NPAT ING2 NR3C2 CCND3 WDFY3 VPS13D MB21D2 CLIP1	down	**
VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP	0.0047140	0.0408360	0.4070179	0.4368782	1.709798	60	TSPAN8 TF HKDC1 EGLN3 PKP2 LSR SHMT2 TNNT2 AP1M2 FAM162A SLC9A3R1 SPINT1 ALDOA SLC39A5 KCNE3 REEP6 ALDOB CTSV SLC13A4 KRT19 CCNG1 PRSS8 ADM CDH1	up	*
GO_REGULATION_OF_ALPHA_BETA_T_CELL_DIFFERENTIATION	0.0046378	0.0404059	0.4070179	-0.3943279	-1.709756	56	TGFBR2 IL23A RHOA ANXA1 ADA HLX GATA3 SOCS5 SMAD7 NCKAP1L CD80 CD83 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 IL18 RIPK2 NLRP3 ZBTB16 HMGB1 RC3H2 IRF4 NFKBIZ CBFB PNP	down	*
GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN	0.0000863	0.0017033	0.5384341	0.3772546	1.709560	175	MDM1 HJURP BRCA1 RACGAP1 E2F8 GTSE1 CENPA TPX2 MCM2 COX6B2 SHMT2 NCAPD2 SPDL1 WDR90 WDR62 EXO1 PAQR4 CCDC77 CENPL EME1 KIF2C MAD1L1 POC1A MPHOSPH9 RAD54L KIF11 FAM162A GET4 CKAP2L DCTPP1 IPO9 INCENP CBX5 HDGF CENPJ RFWD3 NCAPG NUP205 DYNLL2 SAPCD2 CCNE1 TUBG1 UBAC1 TACC3 AARSD1 MBD4 SSRP1 ESCO2 GINS2 ANP32E RAD50 GEMIN6 PRMT1 TDP1 SIRT5 MRPL51 NEFH ATAD2 ECH1 SNRPD2 TPGS2 ZWILCH SUPT3H PAXIP1 VDAC3 DTNBP1 POP4 SEPHS1 DNM1L ILVBL NCAPH TFB1M	up	**
GO_MONOSACCHARIDE_CATABOLIC_PROCESS	0.0046883	0.0407079	0.4070179	0.4511265	1.709279	52	FUT6 XYLB PGM2L1 SORD GPI GAPDH ALDOC PKM PFKP KHK FUT2 ALDOA ALDOB BPGM FOXK1 GALK2 BAD HK2 PFKM PGAM1 GLYCTK TP53 FUT10 ENO1	up	*
GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP	0.0001706	0.0030090	0.5188481	0.3800081	1.709080	161	EIF2B5 GLDC SHMT2 RCCD1 MRPS35 NME1 LDHB NR2C2AP DNPH1 C19orf48 NOP9 PDCD5 EMG1 FAM162A DCTPP1 MRPS30 ALDOA HSPBP1 DHRS13 DDX51 DTD1 ESRP1 ATIC MRPL17 KLHDC9 PSMG3 HMGXB3 TPD52L2 ILF2 SMG5 JOSD2 AARSD1 COL9A2 MRPL11 GINS2 ELAC2 ETV4 KLHDC3 TIMM13 STOML2 CHCHD1 ZNF428 NAT8L SSH3 RABEPK SNAP47 EIF3D ADCK1 TXNL4A VDAC1 ACSF3 HOOK2 TYSND1 ALKBH6 RAD1 CYB5B NDUFAF6 TEAD3 FURIN RPL36 HDAC10 VAC14 NHP2 BATF LOX SPRYD4 PFKL ACOT7 NUDT19 MRPS7 CHCHD5 CDH26 DHX30 PDSS2 TRIM28 C1orf174 SUSD3 CUEDC2 DRG2 RBFA POLR2C MYLK4 PECR TRMT1 SLC7A1 DBH OAS1 PGP SIAH2	up	**
MODULE_177	0.0010254	0.0129553	0.4550599	-0.3599082	-1.709012	87	CD52 LMO2 NR3C1 EDEM1 EIF5 LCP1 UBE2D3 TFRC RHOB FABP5 NFKB1 PTPRC CD53 HLA-DQA1 ARHGDIB BTG1 SGK1 CD48 CUL4A JAK1 CD83 GYPC CLN3 PLCG2	down	*
GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_BINDING	0.0055633	0.0463130	0.4070179	-0.4391150	-1.708966	36	SMAD6 BMP2 ENG TGFBR3 TGFBR2 NODAL SMAD7 INHBA TGFB2 BMP3 TGFB1 SMAD2 FKBP1A	down	*
HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN	0.0052476	0.0443317	0.4070179	0.5151605	1.708926	31	RHPN2 PRSS2 BAMBI TRIB3 ASTN2 CEL MSX1 ASS1 IGSF21 IGFBP5 PPIC TESC	up	*
GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN	0.0000568	0.0011993	0.5573322	-0.3255469	-1.708564	167	LPXN PID1 CD44 CTSW ST3GAL6 MYADM STX11 BCL2A1 PEAR1 ABCB1 PDE2A ATP2B1 B3GNT5 ZDHHC2 PRSS12 IL18R1 GRN PPP3CC NRARP AHNAK CASP1 YBX3 GAA OSTF1 PDE8A CDKN1A ID2 MATK IL7R MAPRE2 IL2RB RAB8B NDNF ATXN1L PTGER2 TBX21 CST7 GPRIN3 NKG7 SMPDL3B ZC3H12D TBRG1 C8orf37 SPOCK2 SYT11 IL18RAP EPB41L5 CDC42EP3 HIGD1C TRAF1 HES2 S100A4 METTL7A ADORA2A RORA GSG1 TOX2 JDP2 ENDOD1 ICOS ITGB1 SLC26A11 MICAL1 ABHD14A	down	**
GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP	0.0000135	0.0003610	0.5933255	-0.3238002	-1.708431	171	TEK PDLIM2 USHBP1 LIPA BMP2 SH2D3C LDB2 CAV1 MYADM NCF2 FUCA1 PILRA MAN2B1 ASAP1 PTPRM NAAA RASGRP4 CLEC7A PARVG CAV2 ADRB1 DES PPP3CA EPB41L2 EVI2B MTMR6 SCP2 RUNX1T1 PLBD1 COTL1 ITGAX PAPSS1 RECK ARHGAP9 EVI2A HGSNAT PRCP TECR ID4 CYB5R1 PRKACA SUCNR1 UVRAG CYP4A22 ALDH3B1 TIMP2 ZNF521 TGFB1 TEC TSC22D1 PLEKHO2 ESYT1 ARHGAP18 SREBF2 LIMCH1 CD3G RNF38 ITCH ACAT1 CBX7 SVIL CX3CR1 ITGAL FPR1	down	***
GO_PRODUCTION_OF_MOLECULAR_MEDIATOR_INVOLVED_IN_INFLAMMATORY_RESPONSE	0.0045456	0.0398198	0.4070179	-0.4002264	-1.708196	51	MYD88 APOD CD36 CLEC7A SIRPA GRN SLC7A2 MEFV TLR4 FCER1G PER1 IL17D SNAP23 APPL1 CHIA CD6	down	*
MIR32_5P	0.0000000	0.0000012	0.7337620	-0.2931600	-1.707670	412	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 NEDD4L BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 PRSS12 MED19 SLC7A11 GPBP1L1 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 FOXN3 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 NOTCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 ZNF804A KBTBD8 MORC3 GRIA1 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 PIK3AP1 ZNF521 PHF3 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 IRS2 NFYC ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 ARPC2 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 MCOLN2 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 DUSP6 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 PIP5K1C MEF2D ZFYVE21 MTFMT ITGA6 ROBO2 DOCK5 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1	down	***
GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS	0.0000099	0.0002763	0.5933255	0.3640288	1.707641	234	HMGA2 DDX11 CDC45 CHEK2 CCNB1 PAGR1 STOX1 NDC80 BRCA1 CDK4 SMPD3 RACGAP1 E2F8 GTSE1 DBF4B KIF14 AURKB ECT2 ESPL1 CDC6 TFDP2 CDC25A DTL CDT1 RANBP1 CASP2 SMARCD3 KIF23 RHNO1 KIF3B MSX2 MAP10 AURKA TPR MSX1 POC1A CXCR5 CDCA5 GPSM2 CDC25C SOX4 EGFR MAD2L1 MDM2 PML CNOT3 STXBP4 NUSAP1 ANAPC5 CDK1 CENPJ E2F1 FEN1 EZH2 CNOT11 SPAG5 EGF RAB11FIP4 MTBP GIPC1 CCNE1 DLGAP5 CNOT2 MTA3 MYBBP1A PKP4 NUDT16 KIF20B ATAD5 CDC7 ANKRD31 SH2B1 CENPV	up	***
MIR4700_3P	0.0010067	0.0128019	0.4550599	-0.3665497	-1.707453	78	SIDT2 TAL1 FYN CAV1 SLC39A8 PAFAH1B2 NR3C1 TSHZ1 CBL LATS2 EPM2AIP1 ZNF365 FOXO1 ERP44 C9orf72 PDCD6IP TREM1 DUSP8 FBXO11 HSPA13 PCGF5 RALB	down	*
GO_CELL_CYCLE_G2_M_PHASE_TRANSITION	0.0000509	0.0010993	0.5573322	0.3641099	1.707355	237	HMGA2 FOXM1 CEP72 TICRR CHEK2 NEK2 CCNB1 CENPF STOX1 BRCA1 CDK4 BRSK1 GTSE1 DBF4B KIF14 CEP70 PLK1 AURKB CDC6 TPX2 CCNB2 CDC25A ORC1 DTL ZFYVE19 CDK5RAP3 DCTN2 HAUS5 CEP250 MELK HMMR BTRC SMARCD3 AURKA ODF2 SFI1 CLSPN CDC25C TOPBP1 CHEK1 PSMD4 PKMYT1 FBXL8 BLM MNAT1 SKP2 CDK1 CENPJ PSMB5 PSMC4 FGFR1OP CEP63 CEP192 TUBG1 NEK10 PSMA5 NINL PSME2 MTA3 AKAP8L FZR1 PSMD2 ATAD5 PPME1 CDC7 CKAP5 PSMB3 CHMP4C WNT10B CDK5RAP2 UIMC1 HAUS6 HAUS4 PSMB4 CEP152 ESRRB ALMS1 CCNA2	up	**
MORF_DDB1	0.0000488	0.0010595	0.5573322	0.3676353	1.707287	210	TRIP13 DDX11 EIF2B5 TOMM34 MCM2 CIB1 WDR62 RUVBL2 DNPH1 SDHA HLTF TP53BP1 BPHL TPR PRKDC TRRAP PEX6 CDC25C ACTL6A PKMYT1 CAD FDXR PHB CNOT3 ERCC2 ALG3 MEA1 KXD1 OARD1 TTI1 RTCB DNAJC7 EIF6 GOLGA3 FANCG ILF2 SSRP1 MLEC TCEA1 DAP3 SLC4A2 KDM3B PSMD2 COPS6 SH2B1 TSTA3 CPSF4 BRD8 AHCYL1 SRRT MRPL28 TFAP4 AATF PDIA4 SMARCC2 NUP62 DOCK3 NFRKB CSNK1G2 PDAP1 PRPF31 BMS1 SNRNP200 RPRD2 CHD3 PARG ADAM15 RANBP3 PWP1 PLIN3 ILVBL SART3 PRKAG1 PARP2 XPO6 PCGF2 DRG1 NELFB HUWE1 TUBGCP2 NSL1 MPST SPRN CS HNRNPAB LRPPRC UBE3C PSMD3 PDXDC1 DRAP1 BECN1 ACTN4 CLTC RABGGTA RAC1 DDB1 ATXN2L YIF1A PRKCSH DNAJC13 POLR2C SUMO4 CLSTN1 DDX46 RERE NCBP2	up	**
GSE8835_HEALTHY_VS_CLL_CD4_TCELL_DN	0.0003721	0.0058397	0.4984931	0.3874251	1.707267	135	RIBC2 HELLS SLC13A3 ELOVL6 DEPTOR B3GAT1 FCER2 CCNB2 LMLN BUB1 CCT5 MMS22L CSRNP3 HOXC6 ARMC12 RAD51AP1 TBC1D8 PTGDR2 BLM HOXB5 FBXO16 MBOAT1 SLC25A10 INCENP C12orf75 GMNN SMG9 GDAP1L1 BBS5 AMPH DNAH7 TSNAXIP1 ADAM28 MAPK13 EPHB2 CNGA4 PRG4 ZSWIM1 DDIT4L GBF1 ZNF76 ARVCF KDM4B TIAM2	up	**
GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN	0.0000316	0.0007336	0.5573322	-0.3207016	-1.706821	177	GCOM1 PECAM1 HSD17B11 EGR2 INPP5K GPCPD1 VAMP2 DYRK1A MKNK1 NR3C1 PDE2A NUMB SLC44A2 UBL3 EIF1 RAB33B GNGT2 BTG2 RANBP9 FOXP1 GLS ADRB2 NFE2L2 MAFG KLF7 FAM49B CDS2 CEP57 GNAQ TAF13 AFF3 RPL17 PIKFYVE NXF1 VAT1 ZFP91 KCTD12 ETS1 IFRD1 UBAC2 RHOQ AZI2 HIVEP2 SRSF6 DUSP5 TOB1 SERINC3 LAT SFT2D1 ING2 STK4 CEPT1 ARPC5 SCAI SKI CYTH1 SPATA13 ARHGEF18 LNPEP TUBA1A RNF167 SRSF11 BCL10 RCSD1 STX16	down	***
GO_FOCAL_ADHESION_ASSEMBLY	0.0015991	0.0180984	0.4550599	-0.3672649	-1.706699	77	ACVRL1 TEK DLC1 WNT4 CORO1C RHOA APOD SFRP1 ROCK2 DUSP3 SORBS1 LIMS1 ROCK1 THBS1 PEAK1 FAM107A MAP4K4 FERMT2 PPM1F EPHA3 TESK2 CLASP2 ACTN2 MACF1 EPB41L5 LIMCH1 PTEN IQGAP1	down	*
chr2q33	0.0010067	0.0128019	0.4550599	-0.3663448	-1.706499	78	BMPR2 SNORD11 HSPE1 BZW1 CLK1 COQ10B PLEKHM3 KLF7 CYP20A1 KLF7-IT1 C2orf69 MOB4 SF3B1 CREB1 TRAK2 SNORD70 AOX1 ORC2 PPIL3 NBEAL1 INO80D METTL21A FAM126B NRP2 HNRNPA1P35 ICOS MIR2355 ANKRD44-IT1 FTCDNL1 CCNYL1 CFLAR KCTD18 ANKRD44 PLCL1 PGAP1 NOP58	down	*
GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP	0.0001031	0.0019831	0.5384341	0.3771719	1.706401	173	FOXM1 MDM1 TICRR PARPBP ACY3 BUB1B CENPF CIB2 DEPDC1B TTK GINS1 CDCA2 RACGAP1 ASPM STIL CCNB2 TYMS XDH TMCC1 GINS4 B4GALT4 TP53BP1 AP4M1 BUB1 CCDC77 TOP2A RAD54L KIF11 L3HYPDH HEBP2 MAD2L1 CKAP2L EHHADH XRCC1 SPC24 BLM TTYH3 INCENP CDKN2C CBX5 CTDSP2 CDK1 CENPJ CENPH KRBA1 EZH2 TRAPPC12 ANKRD39 ZNF606 ARHGEF16 URGCP ANP32E CCDC51 PTER SUPT16H CENPM ANKRD6	up	**
REACTOME_SIGNALING_BY_TGF_BETA_FAMILY_MEMBERS	0.0008126	0.0107995	0.4772708	-0.3522237	-1.706124	94	SMAD6 ACVRL1 GREM2 BMP2 NEDD4L BMPR2 CBL TGFBR2 RHOA ZFYVE16 UBE2D3 CDK9 SMAD7 INHBA JUNB PPP1R15A SKIL FSTL3 UBB TGFB1 PARD6A TGIF1 ZFYVE9 SMAD2 FKBP1A UBE2D1 SKI SMAD4 PPP1CB ARHGEF18 ACVR1C SERPINE1 CCNK NOG SNW1 CCNT2	down	*
FAELT_B_CLL_WITH_VH3_21_UP	0.0056719	0.0469870	0.4070179	0.4845281	1.705951	38	TYMS TOP3B YKT6 PKMYT1 PPP5C CNOT3 SMG5 TK1 HMGA1 CLUH VDAC1 GNA12 EIF4G1 SBNO2 UBTF SAFB TOMM40 E2F4 ZBTB48 ACTN4 SRC SMARCD1 PRKCSH	up	*
GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP	0.0000476	0.0010367	0.5573322	-0.3213141	-1.705638	178	SWAP70 SNX10 CAT FYN LY86 QKI ZCCHC2 SRSF7 VAMP2 MKNK1 CD1C CD22 FGR GGA2 KIAA0355 ENTPD1 ATP6V1H ATP6V1B2 SRSF5 DENND3 LAPTM5 GCA RAP1GDS1 TBC1D4 MAPRE2 SNN STK24 RPL17 USP25 PKIG MYLIP FRY CDC40 PHTF2 SNAP23 PIKFYVE PDCD6IP STX7 DDX5 MORC3 REL UVRAG SLC25A24 AGPS MYL12A VAV3 TSC22D1 KYNU PPID RBL2 TRAC TNFAIP8 ZBTB25 ARPC5 PAK2 LYST PDE8B AIM2 DAZAP2 CNOT8 SMAD4	down	**
GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN	0.0000931	0.0018192	0.5384341	0.3763143	1.705299	175	KIF20A GALNT14 NUP107 KIF18B SORD TTK UBE2Z ASPM MCM2 CDC25A PRC1 EIF3B CAND1 SHMT2 CCT2 UQCC1 BUB1 CCT5 LARS2 KIF2C MCM7 MPHOSPH9 TMEM45A MRPL3 KIF11 SEC61A1 SDHAP1 TOPBP1 CHEK1 AHCY C7orf26 GEMIN4 THOP1 BIRC5 C1orf112 SUN1 E2F1 TRAP1 RANGAP1 TUBG1 PKP4 AHNAK2 NRF1 POLD1 KDM3A PFAS HMGA1 LRRC59 RPA1 PPP6R1 MCM6 PRMT1 TDP1 DOLPP1 C1QTNF3 PRMT5 COG5 CAPN15 PRDM10 TXNL4B PAK4 TUBGCP4 SMC2 TCF3 NCAPD3 ADCK2 BTN2A1 NUP93 FTSJ3	up	**
GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN	0.0000657	0.0013554	0.5384341	-0.3242055	-1.705247	164	ADTRP C18orf32 HCAR2 PLEKHF2 GTF2E2 GPCPD1 SLC15A3 STX11 IL23A LYRM4 ENTPD1 MTF1 PICALM HDC PAG1 PPP2R2A FAM122A IL18R1 NDEL1 CLK1 MCL1 FLI1 CPED1 SNAI1 FMNL3 PTPRC CDS2 IRAK2 CD300C N4BP1 LRRC3 CMTM6 HGSNAT NXPE3 IFNGR1 SKIL EEA1 UBAC2 CREB1 PTGER2 PXK ASTE1 ADNP2 CDK17 ETS2 IFNLR1 PDLIM5 IL18RAP RLF THAP6 G3BP2 GRIN3A KATNA1 MTUS1 MACROD2 SUGT1 CNR2 ITGAL TRMT1L S100A8	down	**
GO_REGULATION_OF_BLOOD_PRESSURE	0.0003942	0.0061068	0.4984931	-0.3376157	-1.705125	123	ACVRL1 HMOX1 ACE EDNRB PPARG EMP2 RAMP2 ADRA1D BMPR2 TBXA2R GAS6 CYP4A11 RHOA ATP2B1 ADRB1 ADRB2 CES1 PDE4D PTPRO PTAFR NPR3 ID2 PRCP SGK1 CTSZ ADRA1A NPR1 SUCNR1 CD34 GPR37L1 SLC4A5 MME CPA3	down	**
GO_PYRIMIDINE_RIBONUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS	0.0058933	0.0482524	0.4070179	0.6447531	1.704511	13	NME1 NME9 NME5 CAD UCK2 UCKL1 NME4 NME7	up	*
GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP	0.0001581	0.0028190	0.5188481	-0.3377872	-1.704396	126	OTUD1 BACH1 NEDD4L CRY2 CD9 DENND2C TEX2 PDE2A RASGRP4 ADRB2 RHOB CYBRD1 ARRB1 TCP11L2 ID3 ITIH5 PRF1 DUSP1 TANC1 HEXB SLC25A33 FAM107A SCEL SGK1 JUN VAT1 BTD PPP1R15A GSTO1 TINF2 SNX9 FOS EHD2 FOSB TSC22D1 DUSP5 TGFB1I1 IRS2 NFYC ADPGK RGS2 GIMAP5 DAPK1 PAIP2 ATF4 ACVR1C PRKCH ZFP36 ATP1B1 SORCS2 DNAJB1	down	**
MORF_DNMT1	0.0006780	0.0094185	0.4772708	0.4021804	1.704240	101	BUB1B ESPL1 MCM2 TYMS SRPK1 ZWINT RUVBL2 NUDT1 CHAF1A CCT5 POLA2 PRKDC TRRAP RAD54L MCM3 DNAJC9 SSBP1 GOT2 PMEL SPAG5 KXD1 DNMT1 SNRPA LMNB2 SSRP1 TCEA1 DNAJC11 MCM6 MCM5 SRSF1 TXNL4A TCERG1 SNRNP200 VDAC3 ZNF131 MRPS27 CLPP TNPO3 SAFB CS XRCC5 NAE1 LRPPRC EBNA1BP2 STMN1 PPM1G KHSRP BUB3	up	**
LIM_MAMMARY_STEM_CELL_UP	0.0000001	0.0000028	0.7195128	-0.2920753	-1.704230	410	LIMS2 EPAS1 PRX WTIP STAC EDNRB RASIP1 CSDC2 IL1B LRRC8C TIE1 THSD1 PTPRE EGR2 BACH1 CAV1 AQP9 QKI CDH13 CDC42EP2 TGFBR3 EOGT AGPAT4 HSPG2 HEG1 CD36 TBX2 PLA2G7 BMP1 LTBP4 TACC1 LIFR PLXNA2 TMEM204 LUZP1 FOXP1 TTYH2 JAM3 TNS1 AKT3 SRGN PDGFA TUBB6 CNN1 LRP4 ADARB1 FABP5 AMOTL1 KCNMA1 SORBS1 PEG3 PXDC1 SLC12A4 ZNF423 THBS1 ARNTL SSH1 CDKN1A CADM1 TMEM255B KCNMB1 VIM AXL JAM2 ARC RECK IGFBP2 LBH SHE CCND2 ELK3 MATN2 ACTG2 PRICKLE2 MYH11 DCHS1 IL24 MRVI1 RASL12 MEDAG CNRIP1 ID4 SCN4B IL6 PODN CCDC3 ETS1 MSRB3 ELP5 RHOJ RAPGEF1 FERMT2 GYPC MALT1 GRASP COL23A1 MCAM GPR3 TSHZ3 FLNC MME ISM1 TCF4 ITGA9 CYGB TGFB1I1 CTNNAL1 GNAI1 GNB4 MYOCD MRGPRF SBSPON MFNG ABI3BP TCF7L1 TAGLN MBNL1 GEM ICAM1 YAF2 LMOD1 PAMR1 OSR1	down	***
GSE24210_RESTING_TREG_VS_TCONV_UP	0.0000218	0.0005402	0.5756103	-0.3204708	-1.704106	176	SLC12A6 KLF13 HHEX CYP27A1 ARRDC4 MYADM C8orf58 MANBA SPATA1 GIMAP6 SYS1 CD22 ANXA1 CNST SH2B3 RAPGEF4 NAAA CYB561A3 TMEM123 ZEB1 EVI2B AGO4 ARRB1 MTMR6 CCDC82 ITM2B ROCK1 PTPRC MRVI1 AFF3 FRY MTMR14 CPEB4 JAK1 RAPGEF1 FRYL COBLL1 AP3B1 PXK KLF2 YPEL2 CD164 AZI2 NAPG KYNU SERINC3 UNC13D SESN1 SLC35D2 CHURC1 CDC42EP3 TRAPPC8 ARHGAP18 FBXO25 METTL7A JMJD1C CYTH1 PAPSS2 CTSH SH3BGRL3 ING1 ITGAL NCF1 PLEKHA2 PIK3CG WDR47 SGPP1 EP300 MEF2D CCPG1 FAM78A	down	***
GO_EXTRACELLULAR_LIGAND_GATED_ION_CHANNEL_ACTIVITY	0.0031918	0.0306075	0.4317077	0.4723842	1.704003	42	GRIK2 GRIA4 GRIN2D GABRP GABRB3 CHRNG CHRNA7 GRIN2A P2RX2	up	*
MIR4777_5P	0.0007230	0.0098802	0.4772708	-0.3550432	-1.703945	91	MED4 KCNN3 FBXO3 ZBTB2 SEMA6D CHMP1B KLF10 TMEM123 SPTBN1 RAB14 HIF3A FMO2 TMED5 RMDN3 PAFAH1B1 GNAI2 CREBRF SCEL CYCS NXPE3 NIPSNAP3B FOXO3 PDE12 CYGB MCUR1 PGGT1B CCR9 UBE2D1 SP100 RAD9B RORA WDFY3 ENY2 NIPSNAP3A MAP4 PHYH KLF15 NDFIP1 PIK3CG SRP14 CFLAR TTC39B KBTBD2 ZNF80 ENPEP CPPED1	down	**
COATES_MACROPHAGE_M1_VS_M2_UP	0.0010424	0.0131118	0.4550599	-0.3657926	-1.703927	78	RASAL2 P2RY13 MARCO TXNIP ADA MALAT1 SLC7A7 FAM124A ARSB MSR1 HAUS2 PLBD1 CADM1 AXL PTGER3 PPP2R5C HLA-DQA1 CRIM1 CNRIP1 SLCO2B1 CAP1 OGFRL1 BLOC1S6 PIK3AP1 GNB4 ACYP2	down	*
REACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE	0.0000207	0.0005170	0.5756103	0.3622970	1.703830	243	CEP72 CEP89 RPGRIP1L NEK2 CHCHD6 RAB3IP MKS1 TUBB2B IFT122 TTC26 CEP70 PLK1 IFT27 EXOC3 CCT2 DCTN2 HAUS5 CEP250 SMARCD3 BBS1 KIF3B FBF1 EXOC4 CCT5 ODF2 SFI1 IFT43 WDR60 IFT172 KIF3C CNGB1 C2CD3 IDH2 IQCB1 CDK1 SSBP1 CEP97 CENPJ CCT3 TCTN2 DYNLL2 SMO PRKAA2 FGFR1OP IFT52 CHCHD3 CEP63 BBS5 CEP192 NPHP1 EXOC7 TUBG1 NINL TUBB2A TUBA3D TUBA8 CNGA4 DNAJC11 NRF1 TRAF3IP1 CKAP5 WDR34 SIRT4 GBF1 TCTN1 CDK5RAP2 WDR35 SIRT5 HAUS6 DYNC2H1 ESRRA HAUS4 UNC119B CEP152 B9D1 ALMS1 CEP164 CLUAP1 TUBA4B MARK4 TCTEX1D1 TTC30B TUBA1C CLASP1 KIF24 PRKAG1 TFB1M CEP290 POLRMT DYNC1H1 PLK4 PPARGC1B AKAP9 PCNT RAB11FIP3 KIFAP3	up	***
PID_FAK_PATHWAY	0.0048245	0.0415946	0.4070179	-0.3929342	-1.703713	56	FYN ELMO1 RHOA ASAP1 RAP1A ITGA5 CRK ROCK2 PTPN21 JUN ETS1 RAPGEF1 PIK3R1 GRB2 RRAS MAPK8	down	*
MODULE_205	0.0000093	0.0002615	0.5933255	0.3604205	1.703618	255	KIF1A DKK1 PRLR TF CDHR2 EGLN3 MDM1 CYP19A1 HJURP SPOCK1 NEK2 CIB2 DNAJC22 MUC16 SRGAP3 SLC25A21 DEPDC1B E2F8 KIF14 TRAIP SAYSD1 TPX2 ZNF117 GALNT10 HPS3 DTL KHDC1 ASPHD2 B4GALT4 RSPH1 TTLL4 BOD1 MAP10 SEMA6C HHAT MSX1 ICA1 FANCD2 GPSM2 CDC25C YEATS2 KCNJ11 C22orf46 FDXR WNT5B TSHR KIAA0556 DNER PPM1E DNAH6 CACHD1 FAM114A1 ULBP2 NARF TRAF5 PLVAP IFT52 MYO19 ST14 DLGAP5 SLC26A2 EPHB2 CENPQ AGPAT5 SPA17 CCDC51 COG4 FKBP14 GNAZ SEC14L2 TCTN1 FANCM TIAM2 CELF4 FCHSD1 PRSS16 TMEM45B CNTN2 ZNF286A INTS8 SUV39H2 B9D1 CCNA2 ZNF93 SHCBP1 PPFIA3 ATG4D FBN2	up	***
PUJANA_BREAST_CANCER_LIT_INT_NETWORK	0.0011191	0.0138723	0.4550599	0.4086517	1.703348	90	CHEK2 BUB1B CCNB1 CDK4 PLK1 RBBP8 CDC25A TP53BP1 FANCA AURKA ATR CLSPN PRKDC FANCD2 MCM3 CDC25C CHEK1 MDM2 BLM CDK1 E2F1 FANCG CCNE1 TUBG1 RAD9A HDAC1 FHL2 ESR1 RAD50 RPA1 PEX5 MSH2 CCNA2 SMARCA4 RAD51	up	*
GSE7219_WT_VS_NIK_NFKB2_KO_DC_DN	0.0000793	0.0015913	0.5384341	-0.3279026	-1.703212	160	CD55 SPN CLDND1 LRRFIP1 PPP4R1 AQP9 S1PR1 ELMO1 GNPTAB NFATC3 FAM49A PDE2A ATP2B1 CYP17A1 B3GNT5 GM2A C1orf21 ECHDC1 FOXP1 LAIR1 IL18R1 CRTAM PSTK ZSWIM6 SELL CD302 PLEK PPP2R5C IL7R PIK3R5 MOB3A CNOT6L UTRN SH3BP5 CD7 TAGLN2 KLRC2 XYLT1 BIN2 SMPDL3B PDLIM1 ZC3H12D CLDND2 EXOC1 MACF1 ME2 IL18RAP SP100 GPD1L CCND3 SMAD4 ARHGEF18 SETX TNFSF8 ATP11B	down	**
GO_NUCLEOTIDYLTRANSFERASE_ACTIVITY	0.0010775	0.0134682	0.4550599	0.3974238	1.702816	108	POLQ PRIM2 NMNAT3 POLE FLAD1 TAMM41 POLR3A RPAP1 POLM POLA2 POLD2 COASY POLR3C POLN TERC CMAS POLE2 POLR3K POLR1C TEP1 NMNAT2 POLR2H POLL POLD1 POLB POLR2J GMPPA NMNAT1 POLR2J3 POLR2I POLR3E MAB21L1 PRIM1 POLR3B CTU1 POLR1B POLR1A GDPGP1 OAS3	up	*
GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_UP	0.0000759	0.0015308	0.5384341	0.3768497	1.702776	172	GRIA4 MCM10 BDH1 ELOVL6 ZDHHC4 CHEK2 BUB1B GINS1 CDCA2 IQGAP3 GTSE1 ABCA12 NUF2 ACAD9 MCM8 XPOT EXO1 POLD2 KIF2C WDHD1 FANCD2 MAD2L1 CKAP2L IPO9 BLM SLC18B1 FADS2 IDH2 ALG3 SLC25A10 WWC1 PARP1 CBX5 ASF1B MRPL37 ANAPC5 ARHGAP39 POLE2 PEG10 PDK1 POC1B TRIM24 DLGAP5 SLC35C2 LMNB2 DTYMK SLC4A2 ATAD5 UBQLN4 LIMA1 L3MBTL2 TMEM106B PIGU UTP20 PRODH CUBN RAB34 STRBP PRIM1 RTEL1 VDAC1 CDC42BPA TPGS2 PPP6R2	up	**
SABATES_COLORECTAL_ADENOMA_UP	0.0005559	0.0080249	0.4772708	0.4026783	1.702687	103	CCNO CPS1 GABRP C2CD4A S100A2 GALNT6 LCN2 MUC5AC FABP6 ANLN MMP1 GRHL3 SP5 CLDN1 TRIM29 MSX2 MSX1 RRM2 SERPINA3 GPSM2 WDR72 HES6 BACE2 CXCL11 DGAT2 PSAT1 CDH3 TRIM7 LGR5 L1TD1 MMP7 ACSL6 ETV4 TNS4 CXCL1	up	**
GSE41176_WT_VS_TAK1_KO_UNSTIM_BCELL_UP	0.0000590	0.0012409	0.5573322	-0.3271150	-1.702083	154	EREG KMO USP12 RAPGEF2 INSIG1 BACH1 AQP9 CDC42EP2 STX11 BCL2A1 FAM49A TOE1 TRA2B RRAGC BTG2 MAP3K8 PTX3 NR4A1 JAM3 AKT3 CNN1 PRDM16 TPSG1 VASP CLIC4 DNTTIP2 MAFF AKIRIN1 SNN NINJ1 KANK1 PPP2CA PSEN1 PPP1R15A WTAP PODXL TAGLN2 TOM1L2 TPRA1 IP6K1 ACSL1 GPR37L1 CDK17 ICAM2 SOD2 IST1 RNF2 ANKLE2 TNFAIP8 RAB5A CALCOCO2 NUP98 RPS13 KCNK7 TLK2 ATF4 DNAJB5 ARFGAP3	down	**
FALVELLA_SMOKERS_WITH_LUNG_CANCER	0.0024208	0.0248011	0.4317077	-0.3777392	-1.702063	68	EPAS1 ENG OTUD4 B3GNT5 EIF1 BTG2 AHRR RNF144B RNF125 MCL1 RHOB RAB12 SRSF5 AQP4 ATP6V0D2 DUSP1 MYH11 ACTR2 UFM1 RCAN1 SOD2 CCL20 WDR1 PRKG1 CYTH1 IQGAP1 SERPINE1 FUS SCAF11 MATR3	down	*
GO_GLYCOSYLCERAMIDE_BIOSYNTHETIC_PROCESS	0.0053304	0.0448708	0.4070179	0.7677854	1.701856	7	UGT8 GAL3ST1 FA2H	up	*
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	0.0000507	0.0010964	0.5573322	0.3646507	1.701817	217	HMGA2 TRIP13 TICRR CHEK2 BUB1B CCNB1 CENPF NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 PLK1 AURKB CDC6 TFDP2 ORC1 DTL ZFYVE19 CDT1 CDK5RAP3 SPDL1 CASP2 BUB1 AURKA TPR MAD1L1 CLSPN PRKDC CDC25C SOX4 TOPBP1 CHEK1 MAD2L1 PSMD4 MDM2 BLM PML CNOT3 CDKN2C CTDSP2 CDK1 RFWD3 E2F1 PSMB5 EZH2 CNOT11 PSMC4 MAD2L2 KLHL22 CNOT2 PSMA5 PSME2 FZR1 PSMD2 PSMB3 CDC20 CHMP4C CDK5RAP2 PRMT1 UIMC1	up	**
CEBPB_01	0.0000110	0.0003012	0.5933255	-0.3133981	-1.701666	204	COL25A1 ASGR1 GLIPR2 IL1B FABP4 P2RY1 MIR22HG RCOR1 PDE1B FLVCR2 P2RY13 DYRK1A TRIB1 IL23A CCNL1 EIF4A1 ITGA5 LUZP1 FOXP1 CLN5 ADRB2 TUBB6 RHOB IL10 MAP2K3 PRDM16 PTGIR SPAG9 MARVELD1 GPR85 SFTPD DUSP1 ELMSAN1 CRIM1 NCKAP5 AFF3 FOXN3 MCMBP RBM39 ETF1 VAMP3 DDX47 C2CD2 MITF RCAN1 PIK3R1 GPR3 SPRY4 PRKCG IRF5 STRN AP1G1 ZFYVE9 SKIDA1 CTNNAL1 PIM1 CSDE1 TOB1 MBNL1 BNIP3L CDC42EP3 SPIB PTCH1 CEPT1 RORA NRP2	down	***
REACTOME_CD22_MEDIATED_BCR_REGULATION	0.0056719	0.0469870	0.4070179	0.4638881	1.701311	46	IGLV3-27 IGKV1-17 IGKV3-15 IGKV3-11 IGKV1-16 IGKV4-1 IGKV2D-28 IGLV1-44 IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGLV7-43 IGLV6-57 IGHM IGLV1-47	up	*
GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP	0.0000226	0.0005545	0.5756103	-0.3199256	-1.701207	176	WEE1 GCOM1 HHEX ZC3H12C HSD17B11 LMO2 MYADM NEDD4L CD22 GGA2 CASP9 PTS UBL3 SLC7A7 RAP1A MAP3K8 LITAF TMEM123 MCL1 TUBB6 TIPARP MPEG1 CASP1 TACR2 YBX3 KLF4 PLAUR PLBD1 CLIC4 SELL EPS15 EVI2A RABGGTB HSDL2 HCK PKIG PHTF2 LIMD1 RAB31 KCTD12 PRKCE HOMER1 KLF2 TCF4 TGIF1 SBF2 PIM1 CCR1 SLC31A1 CD19 FDX1 CTSC MCOLN2 FAM126B RSU1 CTSH SLC38A2 DRAM2 TUBA1A EBF1 ABHD14A UBE3A GPR137B SERP1 MAN1A1 NFIL3 MAP3K1	down	***
GO_LYMPHOCYTE_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.0001257	0.0023331	0.5188481	-0.3304240	-1.701137	143	SWAP70 GAPT SPN CD1C LAMP1 SLC11A1 IL23A ANXA1 CLCF1 ADA FOXP1 HLX LCP1 IFNK GATA3 IL18R1 TFRC IL10 SOCS5 PTPRC TLR4 FCER1G SMAD7 CD80 IL6 PSEN1 PTGER4 GPR183 MALT1 RC3H1 TBX21 ZNF683 PLCG2 TNFSF13 TGFB1 AP1G1 CD86 CD81 LGALS3 MFNG UNC13D CCR6 ICAM1 IL18 NBN SEMA4A RIPK2 NLRP3 HAVCR2 CD19 DOCK10 RORA	down	**
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_UP	0.0001219	0.0022784	0.5384341	0.3768542	1.700831	166	BBOX1 KIF20A MDM1 TICRR BHMT TIMELESS CIB2 NDC80 AGFG2 RACGAP1 DNMT3B ASPM ECT2 CCNB2 ARHGAP33 PRC1 SMUG1 CDT1 KIF23 CEP55 TOP2A CCT5 AURKA CD2AP MMS22L GPSM2 CDC25C TXNDC5 SPC24 IDH2 DET1 KNSTRN CBX5 CDK1 POLE2 BIRC5 SPAG5 LCA5 VPS72 RAPGEF5 RNASEH2A DNMT1 DLGAP5 SNRPA KIF20B KCNB1 CCDC30 SLFN12 CDR2 ASRGL1 MRPS33 CKAP2 HAUS6	up	**
GNF2_SPINK1	0.0055768	0.0463494	0.4070179	0.7670638	1.700256	7	CUZD1 PRSS2 SPINK1 CEL SERPINI2 PDIA2	up	*
GO_T_CELL_MEDIATED_IMMUNITY	0.0008577	0.0113062	0.4772708	-0.3644137	-1.700052	79	CD55 IL1B EMP2 CD1C SLC11A1 RFTN1 IL23A CD8A GATA3 IL18R1 TRAF6 FAM49B PTPRC PRF1 SMAD7 IL7R IL6 STX7 MALT1 TBX21 TREX1 CD1D ZBTB1 CD81 FCGRT ICAM1 IL18 IL18RAP NLRP3 CTSC CD1E	down	*
GO_MICROTUBULE	0.0000016	0.0000573	0.6435518	0.3507614	1.699456	360	KIF1A SAA1 KIF12 KLC3 KIF20A MDM1 DNAH2 RPGRIP1L NEK2 KIF18B TUBB2B RACGAP1 GTSE1 KIF14 SPAG17 ASPM PLK1 AURKB TPX2 DNAH3 PRC1 DYNC1I1 CCT6A KIF27 CDK5RAP3 DNAH14 CCT2 DCTN2 DNAI1 HAUS5 TTLL4 DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 KNTC1 KIF3B MAP10 CCT5 AURKA ODF2 KIF2C MAP1LC3C TEKT2 FSD1 HOOK1 DCDC2 KIF11 DNAH8 GAS8 KIF3C DNAH11 TRPV4 PSRC1 INCENP KNSTRN NUSAP1 CDK1 DNAH6 KIF5A CENPJ BIRC5 CCT3 TTLL9 JAKMIP1 SCTR KIF19 SPAG6 KIF2A KIF7 DYNLL2 SPAG5 DNAH5 KLHL22 TUBG1 DNAH7 NINL TUBB2A TUBA3D KIF22 DNM1 TUBA8 KIF21A HID1 MAP6D1 KIF20B POLB CCT7 KLC2 KLC4 CKAP5 TUBG2 TTLL3 CDK5RAP2 DYNC1LI2 KIF21B EML6 TBCA CKAP2 DNAI2 HAUS6 DYNC2H1 FAM161A RAB3D KATNB1 SKAP1 TTLL6 HAUS4 APC2 NAV1 TUBGCP4 SYBU CCDC181 DNAH1 HOOK2 TUBA4B TPGS2 CDK5 TBCB BCAS3 CAMSAP3 CENPE MAP1LC3A SRPRB GOLGA2 TTC30B DCDC1 TUBA1C MAP9 DNM1L TTLL5 CLASP1 KIF24 MAP2K2 ROR2 DNAL4 SHROOM1 DYNC1H1 TEKT1 BAG2 GSK3A RUSC1 FAM110C PCNT TUBGCP2 KIFAP3 LZTS2 PARP4 RCC2 TPPP3 NDRG1 TMEM214 KIF6 TPPP LRPPRC REEP4 DYNLT1 CALM3 DNAH9 TUBGCP5 KIF3A STMN1 DCTN3 DNAL1 SKA3 SKA2	up	***
GO_PYRIMIDINE_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS	0.0058248	0.0478359	0.4070179	0.5822312	1.698303	19	TYMS NME1 NME9 NME5 DCTPP1 CAD UCK2 UCKL1 DTYMK NME4 NME7	up	*
WEST_ADRENOCORTICAL_TUMOR_UP	0.0000056	0.0001713	0.6105269	0.3586255	1.698213	273	PCSK6 FOXM1 KIF20A PARPBP FANCI ELOVL6 BUB1B NEK2 CCNB1 CENPF IGF2BP3 PBK KIF18B RACGAP1 KIF14 ASPM PTTG1 ESPL1 TPX2 GAPDH NNT MCM2 CDC25A PRC1 DTL CCT6A CAND1 XPOT ZWINT DCTN2 LSM5 BZW2 MELK NUDT1 CHAF1A BUB1 TOP2A AURKA YKT6 KIF2C MAD1L1 RRM2 RHOBTB3 CDC25C ORC6 KIF3C CAD TFCP2 SKP2 TMEM106C CDK1 RFWD3 GMNN EZH2 RALGPS1 FGFR1OP TPD52L2 DNMT1 INTS7 CCNE1 DPP3 CDC23 VPS41 TUBB2A HDAC1 DAP3 EPB41L4B TWF1 SLC1A3 ATP13A1 CENPM ACLY CDK5RAP2 CLINT1 UBE2V2 KDM4B YIPF2 LSM4 MED27 GLO1 SMARCA4 VDAC1 RFC5 WDR77 LPIN1 ZWILCH FBN2 TMED9 TARBP2 ANKMY2 SRPRB SLC36A1 PPIA ENO1 TUBA1C RAD1 PI4KB KHNYN SART3 NPTX2 COPE XPO6 DYNC1H1 ACSM3	up	***
GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN	0.0002032	0.0034905	0.5188481	0.3773540	1.697729	164	TRIP13 SPICE1 PARPBP CCDC34 CENPF PBK C6orf141 CDCA2 ASPM AURKB ECT2 CCNB2 CYP27B1 TYMS DTL RANBP1 MELK MKI67 BUB1 DPY19L1 HAVCR1 E2F2 CENPW SMYD2 GCAT SBK1 GPSM2 CDC25C CHEK1 SPC24 EHF INCENP NCAPG2 NUSAP1 ASF1B UCK2 BIRC5 FAM114A1 DNA2 ITPKA ACTR3B CENPP ZNF606 HDHD3 KIF22 ZNF239 ENPP2 CNDP2 CDC20 EML6 ZRANB3 HAX1 PRSS16 GNAL GADD45G CCNA2 NME4 CPOX SMC2 CENPE EPSTI1 BPNT1 UBE2C KCNK6 TTC5 AVEN COMTD1 NOD1 HINT1 TMPRSS4 KIAA1841 HSD17B7	up	**
VANTVEER_BREAST_CANCER_ESR1_DN	0.0000356	0.0008129	0.5573322	0.3603244	1.697379	242	CA9 HJURP LAD1 KCNK5 TICRR GPT2 GABRP PROM1 BAIAP2L2 UGT8 PRTFDC1 PKP1 PRIM2 PHGDH CDCA7 TTK ANLN GMPS STIL KRT16 CDCA8 CENPA GAPDH CCNB2 MYBL2 NCAPD2 LDHB PLEKHG1 MELK CEP55 KCNN4 TRIM29 BUB1 FANCA IDO1 MYO10 KIF2C RSRC1 TRPV6 PDCD5 TMEM45A RAD54L GPSM2 PLTP HEBP2 TOPBP1 PDZK1IP1 ASS1 PFKP BLM TTYH3 HDGF TNFRSF21 UCK2 C1orf112 PSAT1 STEAP3 CDH3 RAB6B ATAD3A DIAPH3 ILF2 ST14 CTSV USB1 IL15RA IFNAR2 MMP7 ASNS	up	***
GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS	0.0000000	0.0000000	0.8140358	0.3358868	1.697191	711	HMGA2 TRIP13 TP63 DDX11 FOXM1 EGLN3 EYA1 RUVBL1 CDC45 TICRR PARPBP MCM10 FANCI CHEK2 EYA2 CCNB1 TIMELESS POLQ UBE2T PAGR1 CHCHD6 DDIT4 PIF1 BRCA1 BRSK1 E2F8 GTSE1 NPAS2 PMS2P5 POLE NABP2 PLK1 PTTG1 WDR70 TFDP2 FIGNL1 RBBP8 UHRF1 ACER2 MCM4 MCM2 RAD54B PMS2 XRCC2 DTL CIB1 MCM8 LIG3 MAP2K6 GINS4 SMUG1 MRPS35 CDK5RAP3 MAGEF1 IKBKE RUVBL2 CASP2 EXO1 NUDT1 CHAF1A C9orf116 TP53BP1 POLM RHNO1 FANCA CCDC13 BRAT1 EEF1E1 AUNIP TOP2A AURKA EME1 CBX3 REC8 ATR POLD2 IRF3 SMARCAL1 MCM7 ASCC2 MSX1 CLSPN SMYD2 MMS22L CDCA5 PRKDC TRRAP WDHD1 WNT1 HELB RAD54L FANCD2 MCM3 CHAF1B CDC25C SOX4 EGFR LIG1 EME2 MORC2 TOPBP1 CHEK1 NEK11 ACTL6A RAD51AP1 XRCC1 MDM2 PRMT6 MRPS11 BRIP1 RAD18 BLM PPP5C PML CNOT3 PLA2R1 ERCC2 MNAT1 STXBP4 RECQL5 DYRK2 PARP1 POLN CBX5 PAK1 ING4 CDK1 POLE2 RFWD3 ZNF652 EEPD1 E2F1 UNG DNA2 AP5Z1 NEIL3 FEN1 CNOT11 METTL3 OARD1 CBX1 MAD2L2 RECQL4 STK11 RNASEH2A POLR2H FANCG CEP63 INTS7 CDK3 DCLRE1C FANCF CNOT2 SPATA18 POLL MBD4 RAD9A MC1R KIF22 RAD51D SSRP1 COPS7B FBXO4 NFATC4 ESCO2 MGMT GINS2 FZR1 NUDT16 TCEA1 USP43 TRIM32 BCL2L12 POLD1 POLB ATAD5 PARP9 COPS6 SLX4 CDC7 RAD50 UBQLN4 SUPT16H PALB2 TWIST1 SIRT4 HMGA1 ASCC1 BCL2L1 RPA1 POLR2J BAD FANCM UBE2V2 MCM6 MGME1 THOC5 WRNIP1 PRMT1 XRCC4 MCM5 ANKRD1 TDP1 ZRANB3 UIMC1 NEK4 TFAP4 HMCES AATF POLR2I IGHMBP2 PMS2P1 MSH4 PMS1 MCRS1 MSH2 NFRKB DTX3L RTEL1 RFC5 WDR4 CEP164 INO80E RAD51 TNKS1BP1 EYA4 PAXIP1 NUDT16L1 WDR76 SIRT6 PNKP TONSL PARG BCL6 XPC MPG SWI5 TP53 NEIL1 APEX1 FBXO45 RAD1 E2F7 DDB2 MUC1 PIAS4 MRPS26 IMMP2L ACTR5 TMEM161A IFI16 TIPRL ERCC3 ALKBH2 PARP2 TTC5	up	***
GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN	0.0001136	0.0021482	0.5384341	0.3751493	1.696789	171	EGLN3 MCM10 FANCI PBK METTL1 GINS1 RACGAP1 TRAIP POLE SPP1 STIL NUF2 CDC6 TPX2 TFDP2 UMPS TDRKH COQ3 NUDT1 CPD DPCD RRM2 CDCA5 RAD54L CHEK1 IFT172 COX19 DCTPP1 DSCC1 MTG1 PSRC1 CKS1B NCAPG2 ASF1B NCAPG PSAT1 CENPP INTS7 UBE3D ASNS CNDP2 CENPK GEMIN6 CPSF4 SLFN12 METTL2B MRPL41 HAX1 ATAD2 ZNF580 TIGD2 STAB1 SHCBP1 PRPF31 LPGAT1 RAD51 OXCT1 UHRF1BP1	up	**
GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY	0.0008060	0.0107468	0.4772708	-0.3606120	-1.696645	82	PHACTR1 DLC1 WNT4 GPR65 ARHGEF15 INPP5K BAG4 S1PR1 CDC42 RHOA RGCC SFRP1 SORBS3 ROCK2 ARRB1 SORBS1 ROCK1 SRF WASF2 ARHGEF10 PTGER4 PIK3R1 PPM1F WNT11 CLASP2 LIMCH1 CUL3 RAPGEF3 SYNPO2L	down	*
chr5q35	0.0008610	0.0113425	0.4772708	0.3962443	1.696296	112	CDHR2 CPLX2 GABRP SUDS3P1 CBY3 FAM153B FAM153A THOC3 ZFP62 SFXN1 STC2 SPDL1 SIMC1 BOD1 MSX2 B4GALT7 MGAT4B ZNF346 TRIM41 SNORA74B TRIM7 GPRIN1 RNF44 ZNF454 ZNF354A TBC1D9B TSPAN17 DBN1 RAB24 CLTB RMND5B HMGB3P22 PHYKPL UIMC1 NSD1 SH3PXD2B SCGB3A1 FBXW11 ERGIC1 GRM6 TMED9 HRH2 MXD3 PRDX2P3 ZNF354B DDX41 ADAMTS2 TRIM52 FAF2 NHP2 NPM1 RUFY1 HNRNPAB	up	*
GO_CHROMOSOME_ORGANIZATION_INVOLVED_IN_MEIOTIC_CELL_CYCLE	0.0060487	0.0492954	0.4070179	0.4780828	1.696224	40	TRIP13 BUB1B NCAPD2 STAG3 BUB1 REC8 SYCP2 FANCD2 HORMAD1 BRIP1 SUN1 CCNE1 RAD50 ANKRD31 MEI1 MSH4 RAD51 SMC2 NCAPD3 NCAPH MLH3	up	*
SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN	0.0022248	0.0232485	0.4317077	0.4168536	1.695575	74	ATP6V0A4 ALDH3B2 GPR87 TP63 EPN3 PROM1 DNAJC12 TTC39A SLC27A2 STC2 TJP3 HOOK1 MDK PDZK1IP1 TBC1D8 PERP MRPS30 GRB14	up	*
MIR4665_5P	0.0004986	0.0073344	0.4772708	0.3920023	1.695302	120	ATP10B GRIK2 SPICE1 FOXA3 PCDHGA10 SYNPR IGF2BP3 PCDHGA9 PCDHGA5 PCDHGA7 IP6K3 UBE2Z PCDHGA1 PCDHGB3 NAALADL2 PRKCA PCDHGA11 PCDHGA8 PCDHGA12 WDHD1 PCDHGB7 PCDHGA3 CCDC148 SPINT1 ZNF32 DCLK1 C12orf75 PPM1E SDCBP2 KSR2 SSX2IP PCDHGA2 DVL3 PIGG ADAR	up	**
GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE	0.0000055	0.0001685	0.6105269	0.3565950	1.695302	281	HMGA2 TRIP13 BRINP1 TICRR CHEK2 BUB1B CCNB1 CENPF NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB PTTG1 CDC6 TFDP2 ORC1 ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 NLE1 KNTC1 BUB1 TOP2A AURKA EME1 TPR MAD1L1 CLSPN PRKDC TOM1L1 CDC25C SOX4 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 BLM PML CNOT3 PTPN3 CDKN2C CTDSP2 CDK1 RFWD3 E2F1 PSMB5 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 CNOT2 PSMA5 RAD9A PSME2	up	***
MIR518A_5P_MIR527	0.0000116	0.0003157	0.5933255	-0.3103144	-1.695281	216	GCOM1 ABHD5 RBMS2 NUP54 TRPC3 OTUD1 QKI SRSF7 OTUD4 PSMD5 ZEB2 HBEGF ENTPD1 RAP1A PPP1R15B PLXNA2 C1orf21 FZD4 HIPK3 TMEM123 LAMTOR3 PDE4D RHOB TLE4 AGO3 TBX4 ANKRD10 MAP1LC3B GPR85 CTBS ID2 KCTD20 JAM2 CXXC4 WASF3 NUS1 AKIRIN1 FOXN3 CREBRF DCP1A SYNPO2 SGK1 SOCS3 RAB8B PDCD6IP FYTTD1 PIK3R1 FRYL GTDC1 NAA30 RBKS FOXO3 ZFAND6 ZNF521 ISM1 TCF4 STRN DCK VAMP4 CNOT7 ATXN1 INO80D ARPC2 POLR2M ZDHHC21 KPNA4 STK4 MAFK RNF38 RORA NR3C2 ELFN1 MIER3	down	***
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP	0.0000000	0.0000007	0.7477397	0.3389762	1.694797	579	HELLS NXPH4 AK4 PARPBP FANCI GPT2 ELOVL6 BUB1B CCNB1 CCDC34 CENPF IGF2BP3 PRTFDC1 COA1 PSPH GGCT PBK TTF2 SLC2A1 PHF14 BRCA1 PHGDH CDCA7 TTK GINS1 RACGAP1 IQGAP3 GTSE1 KIF14 ANLN CCDC14 GMPS STIL TTC26 ECT2 CDC6 SFXN1 TFDP2 NNT FIGNL1 STC2 RBBP8 MCM4 HOXB7 MCM2 TYMS PRC1 HPS3 DTL CCT6A MCM8 MIS18A ZWINT SPDL1 NME1 C5orf34 CLDN1 GFPT1 MKI67 HLTF KNTC1 CCDC77 DPY19L1 AURKA NUP155 CBX3 WDR3 ATR POLD2 YKT6 TPR KIF2C MCM7 CENPW RSRC1 PRKDC RHOBTB3 PDCD5 TMEM45A WDHD1 KISS1R ZNF146 FANCD2 GPSM2 LMNB1 TOPBP1 CHEK1 DNAJC9 ORC6 MAD2L1 RAD51AP1 RAD18 PSRC1 CKLF RBAK MIPOL1 GPX8 CKS1B NUSAP1 CBX5 MRPL37 OSMR CDK1 SSBP1 UCK2 RFWD3 ATIC NPM3 NCAPG SNAPC1 KIF2A PSAT1 STEAP3 FEN1 SSX2IP MRPS12 NLN MAD2L2 DIAPH3 LAPTM4B SRD5A1 RNASEH2A CHCHD3 HSPA4L DNMT1 INTS7 CCNE1 TUBG1 DLGAP5 NADK2 PSMA5 LMNB2 LONP1 OSBPL3 DTYMK CENPQ GINS2 LINC00662 AGPAT5 KIF20B ASNS GFM2 FKBP14 TWF1 DENND5B ENC1 SASS6 P4HA1 SUPT16H FAF1 FBXO22 ZNF780B UBE2V2 ODF2L MCM6 RAI14 CKAP2 SRPK2 XRCC4 HEATR1 SNRPD1 HAUS6 C5orf22 DYNC2H1 RCC1 CHRNA5 ATAD2 GTPBP10 KLHL7 AP2S1 SUV39H2 PMS1 CCNA2 PRR11 SHCBP1 ABCF2 WDR4 BMS1 TPGS2 ZWILCH MICU1 ACP1 WDR76 SMC2 PFDN4 DNAJC10 TRUB1 PAICS UBE2C CDKAL1 ENO1 ZC3HAV1L DNM1L ZNF367 C4orf46 PPP1R14B CALU BRIX1 IFI16 TIPRL ERLIN1 NQO1 GEMIN2	up	***
GO_R2TP_COMPLEX	0.0016856	0.0187617	0.4550599	0.9018703	1.694646	4	RUVBL1 RUVBL2 PIH1D1	up	*
PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP	0.0019594	0.0211131	0.4317077	0.4356614	1.694517	59	COPB2 GOLPH3L COPG2 COPG1 KDELR2 PSMD4 CBY1 PSMC4 PSMA5 ASNS SIL1 PSMD2 GOLM1 PSMB3 PRSS16 PDIA4 PSMB4 ERGIC3 GOSR2 COPZ1 COPA ERGIC1 TMED9 TBCB TRAPPC6A COPE	up	*
BAKKER_FOXO3_TARGETS_UP	0.0060917	0.0495829	0.4070179	-0.4034921	-1.693933	48	PNPLA6 SLC12A6 CITED2 ASAH1 KLF6 SIRPA TCP11L2 CPT1A PINK1 DSTN GNAI2 BTG1 DCP1A CPEB4 OSBPL9 NQO2 RGS2 PGGT1B RBL2 SESN1 KIT CSF2RB CDKN1B HIPK1 XPO7	down	*
MIR606	0.0016212	0.0182877	0.4550599	-0.3641239	-1.693498	80	COL25A1 MBOAT2 CD44 GNPTAB PPM1D CNST CAV2 SLC7A11 SFRP1 HNRNPU UBE2D3 RUNX1T1 MAP1LC3B RBPJ DDX60L ASNSD1 WTAP SLC10A7 TCF4 ANKRD13A HFM1 POLK MBNL1 RPP30 EPHA4 BRWD1 ZDHHC21 FDX1 HNRNPC RASSF8 ACADM DNAJB5 ELP4 PRTG XRN2 RMDN1 SCAF11 SMARCA5	down	*
GO_ALPHA_BETA_T_CELL_DIFFERENTIATION	0.0008092	0.0107595	0.4772708	-0.3528474	-1.693407	91	SPN TGFBR2 IL23A RHOA ANXA1 ADA FOXP1 HLX GATA3 IL18R1 FUT7 SOCS5 SMAD7 NCKAP1L CD80 IL6 PTGER4 CD83 GPR183 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 GPR18 IL18 SEMA4A RIPK2 NLRP3 RORA ZBTB16 TNFSF8 HMGB1 IRF1 RC3H2 IRF4 NFKBIZ CBFB PNP	down	*
GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_DN	0.0003891	0.0060463	0.4984931	0.3827100	1.692868	140	DNAJC22 SLC2A1 ASIC1 LAMP5 DTL NCAPD2 WDR90 FANCA POLA2 MCM7 SMYD2 KIF11 CHAF1B XXYLT1 TOPBP1 C7orf50 SLC25A39 CAD PPIC FAM135A E2F1 UNG KCTD13 GJB3 DHX33 MECR SF3B3 SNRPE ZMAT5 DAP3 SGSM3 RHD PPME1 CHPF RNF187 TSTA3 CENPM ERBB3 TUBG2 DNMT3A MCM5 TMEM147 ALG8 PRIM1 DBNL NDUFA8 MXD3 TBL3 MSRB1 CSTF1 TOMM7 MED22 RPL36 TMPO RASAL1 NPM1 PRCC ARFIP2 CDPF1 SHMT1 GDF11 E2F4 CALM3 PPP4C SAMD14 PFKL	up	**
GO_NEGATIVE_REGULATION_OF_MULTICELLULAR_ORGANISMAL_PROCESS	0.0000000	0.0000000	0.9325952	-0.2682157	-1.692830	932	SLC6A4 TNR FFAR4 SMAD6 LIMS2 ANGPT4 DAB1 RBP4 SEMA6B RAB11FIP1 SEMA3G SEMA6A ACP5 ACVRL1 NOVA2 SOSTDC1 HMOX1 TEK EDNRB DENND5A TAL1 KLF13 PPARG ADTRP HHEX GATA2 IL1B TIE1 WNT4 RAPGEF2 THBD BMP2 PCSK9 FIG4 ARHGEF15 ECSCR SOX17 DDX6 CORO1C CALCRL BMPR2 GTF2I CTDSP1 TBXA2R HMGCR MIR27B IL1RL1 CD9 GAS6 SLC11A1 TGFBR2 NFATC3 TRIB1 LILRB3 IL23A HSPG2 RHOA APOD SEMA6D ANXA1 TBX2 WWC2 MIR146A MMRN2 ATP2B1 SH2B3 FBXO7 ASAP1 PTPRM CARD16 SEMA3B ADA CD33 FOXA2 ADAM17 LMNA ANXA5 RNF125 PAQR3 HLX ADIPOR1 ABHD6 EIF4E ADRB1 GATA3 PPP3CA SIRPA RB1 RGCC ADRB2 IL18R1 NFE2L2 GRN SFRP1 SPRY2 WNT3A SRGN ARHGEF2 PDE4D ZNF365 APOC1 PDGFA FOXC2 NODAL CST3 LRP4 GPR4 IL10 ROCK2 ARRB1 SNAI1 NRARP FOXO1 KCNMA1 PTPRO MEFV TRIM46 DAAM2 TACR2 YBX3 KLF4 PLAUR REST ZNF423 ID3 ROCK1 THBS1 ARNTL ADAMTS9 SOCS2 CLDN5 SOCS5 KLF7 NPR3 CCL3 NFKB1 PDE3B PTPRC VIM AXL ID2 TLR4 MIR24-2 PTGER3 SFTPD SMAD7 INHBA TBX5 ZNF706 UBASH3B PAFAH1B1 GNAI2 RUFY3 HES1 MIR17HG AKIRIN1 KREMEN1 ARHGDIB TGFB2 GNRH1 PROCR SRF SRGAP2C NCKAP1L KANK1 MYLIP RBPJ WNT9A IL17D ID4 CNTF PPP2CA AREG IL6 CD160 PSEN1 HPGDS NOTCH1 LIMD1 GABPA CUL4A CTSZ ADRA1A PDE5A CARD8 CNTN4 TYROBP IFNGR1 PTGER4 BAG5 IFRD1 PIK3R1 CD83 LSM1 NPR1 RC3H1 RTN4R REL PRKACA TRAK2 FSTL3 TBX21 TIGIT IP6K1 CD34 GPR37L1 KLF2 RUNX3 SRSF6 EPPK1 CD74 WNT11 SAV1 TGFB1 ISM1 SERPINB1 MTMR2 LRRC32 PDCD1 GLRA1 MEIS1 MYOCD CCR1 TOB1 NPTN CRY1 GATA6 N4BP2L2 RGS2 GPR18 PDE4B TSPO SYT11 LDLRAD4 FGF2 PCM1 VASH1 TFPI EPN2 ARRB2 OSR1 SEMA4A RTN4 EPHA4 NLRP3 TOB2 DIXDC1 PTCH1 SP100 HAVCR2 EPHA2 ULK2 STK4 NFKBIA CTSC EDN1 FOXJ2 PTEN SKI LTBP3 PRKG1 GPR171 FGFR1 ITCH LDLR DOCK4 NRG1	down	***
GO_LEUKOCYTE_MEDIATED_CYTOTOXICITY	0.0020316	0.0216984	0.4317077	-0.3658278	-1.692753	76	EMP2 CLEC12B CD1C LAMP1 IL23A DNASE1L3 SERPINB9 CRK CRTAM FAM49B CADM1 PTPRC PRF1 IL7R CD160 TYROBP STX7 AP1G1 CD1D KLRC4-KLRK1 FCGRT UNC13D ICAM1 IL18 IL18RAP ARRB2 HAVCR2 CTSC CD1E KLRK1 LYST	down	*
MIR608	0.0001802	0.0031408	0.5188481	0.3753168	1.692731	169	ONECUT2 ENTPD2 MEX3A PCDHGA10 CPLX2 FAM177B PCDHGA9 PCDHGA5 PCDHGA7 ASIC1 PCDHGA1 PCDHGB3 RGS6 GRIN2A VSTM2L EFNA5 PCDHGA11 PCDHGA8 C9orf116 PCDHGA12 MAP3K13 ANKRD52 PCDHGB7 PCDHGA3 WDR66 EGFR SLC9A3R1 MSI1 CYP2W1 TTYH3 MEOX1 SLC45A3 TTBK1 IGFBP5 SRCIN1 NAV2 ZNF584 KSR2 HMGXB3 PCDHGA2 CCL21 NPTXR DVL3 SEMA4G SYNGAP1 ZBTB7B EPN1 MDGA1 RAI1 KIF21B BSN GNG4 TFAP4 TBC1D16 MMP24 LHPP PATZ1	up	**
GO_AMINOGLYCAN_CATABOLIC_PROCESS	0.0053388	0.0449250	0.4070179	-0.3965741	-1.692608	51	LYVE1 GPC5 CD44 CHIT1 FUCA1 HSPG2 ARSB PRELP HPSE2 CTBS HPSE GLB1 HEXB HGSNAT IDS CHIA TGFB1	down	*
GO_HOMOLOGOUS_RECOMBINATION	0.0042609	0.0380081	0.4070179	0.4788748	1.692226	39	TRIP13 MND1 RAD54B TOP2A EME1 REC8 RAD54L EME2 BRIP1 RAD51D SLX4 RAD50 ANKRD31 KLHDC3 FANCM MSH4 RAD51 MUS81 MLH3 C11orf80 HDAC10 RMI1 MSH3 RAD51B	up	*
GO_G1_DNA_DAMAGE_CHECKPOINT	0.0045196	0.0396937	0.4070179	0.4295422	1.692162	61	CHEK2 CCNB1 E2F8 GTSE1 TFDP2 CASP2 AURKA PRKDC CDC25C SOX4 MDM2 PML CNOT3 CDK1 RFWD3 E2F1 CNOT11 CNOT2	up	*
GO_PYRIMIDINE_CONTAINING_COMPOUND_METABOLIC_PROCESS	0.0016830	0.0187544	0.4550599	0.4100057	1.692089	83	CPS1 GPAT2 THTPA TYMS UMPS SMUG1 DPYS TAMM41 NME1 NME9 NME5 DCTPP1 CAD UCK2 UNG ENPP3 UCKL1 UPP2 MTOR MBD4 DHODH TK1 DTYMK AGPAT5 LCLAT1 NT5M	up	*
GO_POSITIVE_REGULATION_OF_LOCOMOTION	0.0000000	0.0000003	0.7749390	-0.2837412	-1.691903	483	ANGPT4 SEMA6B SEMA3G SEMA6A SASH1 FOXF1 HMOX1 SWAP70 TEK CXCL16 PECAM1 GLIPR2 GATA2 SPN IL1B RDX RAPGEF2 BMP2 CDH5 BAG4 CAV1 MYADM CDH13 BMPR2 C5AR1 S1PR1 FGF10 MIR27B NEDD9 VAPA GAS6 TGFBR2 IL23A FGR RHOA NUMB SEMA6D ANXA1 MIR146A PLA2G7 SEMA3B HBEGF ADAM17 CLEC7A ITGA5 HSPB1 FOXP1 CAV2 GATA3 PPP3CA NFE2L2 GRN CRK AKT3 SPRY2 ARHGEF2 PDGFA FOXC2 RHOB MAP2K3 ROCK2 STAT5A AMOTL1 SNAI1 SDCBP TACR2 PTAFR DAB2 THBS1 STX3 SPAG9 CCL3 SSH1 ITGAX PTPRC SELP CCL4 JAM2 XCL2 PIK3C2A OXSR1 NUS1 GNAI2 RUFY3 ANXA3 AKIRIN1 MAPRE2 TGFB2 SRGAP2C NCKAP1L MYO1C FAM107A SLC8A1 FLT1 IL6 JUN NOTCH1 ETS1 RAC2 MAP4K4 ELP5 DUOX1 RHOJ PODXL CCR7 DAPK2 PIK3R1 ACKR3 PRKCE DOCK8 SUCNR1 PPM1F MCAM PLCG2 CD151 PTP4A1 CD74 WNT11 CCR4 TGFB1 FPR2 MIR23A MIA3 IRS2 SOD2 LGALS3 CCR1 CLASP2 PLAA SPOCK2 ADAM10 CCL20 CCR6 ICAM1 FGF2 EPB41L5 CHMP3 SEMA4A RTN4 IQSEC1 TIAM1 CXCR4 VPS4B	down	***
KRAS.KIDNEY_UP.V1_DN	0.0017177	0.0190288	0.4550599	0.4061562	1.691443	89	SLC9A3 B3GALT5 NPC1L1 ZDHHC8P1 SLC5A5 IGKV3D-15 CHRNG GPR35 TENM2 KLHDC8A SGK2 LILRB4 VILL LRRC31 CETP NPFFR1 CXCL10 SLC6A20 FOXA1 IFI44L LIPE MDFI EDN2 CXCL11 DDX51	up	*
GO_POSITIVE_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION	0.0022449	0.0233732	0.4317077	-0.3834330	-1.691280	59	GPR17 F2RL3 GPR65 ADCYAP1R1 FGF10 RASGRP4 GPR4 ARRB1 EPOR MAPRE2 NOTCH1 MAP4K4 SHOC2 RAPGEF1 GRB2 RTN4R IRS2 GPR18 SYNPO2L NRG1 LPAR6 CDON	down	*
REACTOME_ACTIVATION_OF_NIMA_KINASES_NEK9_NEK6_NEK7	0.0061314	0.0497847	0.4070179	0.7629411	1.691118	7	CCNB1 PLK1 CCNB2 CDK1	up	*
MODULE_321	0.0013422	0.0159908	0.4550599	-0.3396648	-1.691107	103	LRRC8C PTPRE CD44 CORO1C FOSL1 TGFBR2 ITGA5 ANXA5 KLF6 BTG3 GMEB1 FABP5 YBX3 ACSL3 CCND2 ACTG2 CLIP4 PROCR KANK1 SERPINB8 IFNGR1 FERMT2 LPCAT2 TNFRSF10B RRAS CTNNAL1 APLP2 LTBP1 EPHA2 SOAT1 CTSC NRP2 NRG1 CREG1 EHD4 CNN2	down	*
GO_MUSCLE_CELL_PROLIFERATION	0.0000625	0.0013045	0.5384341	-0.3193618	-1.690231	169	RBP4 EREG HMOX1 PPARG CALCRL CDH13 S1PR1 HMGCR PRKAR1A MIR27B TGFBR3 TGFBR2 TRIB1 APOD TBX2 HBEGF FOXP1 TRAF6 TCF7L2 FOXC2 CNN1 IL10 PTGIR PTAFR KLF4 THBS1 NPR3 ABCC4 CDKN1A ID2 TBX5 GNAI2 MIR17HG AKIRIN1 TGFB2 RBPJ IL6 JUN NOTCH1 NPR1 SAV1 PIM1 SOD2 MEIS1 NQO2 MYOCD GATA6 RXRA FGF2 IL18 SF1 EDN1 FOXJ2 PTEN PRKG1 FGFR1 MIR548C ZFPM2	down	**
GO_NUCLEOBASE_CONTAINING_COMPOUND_KINASE_ACTIVITY	0.0043681	0.0387013	0.4070179	0.4782650	1.690071	39	AK4 AK8 NME1 DLG1 CARD11 NME9 NME5 LRGUK UCK2 AK7 UCKL1 TK1 DTYMK RAD50 NME4 NME7 PNKP TK2 DGUOK AK9 CMPK2	up	*
GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP	0.0000271	0.0006440	0.5756103	-0.3178072	-1.689942	176	FCN1 CXCL16 NUP54 GPR65 SIK1 BACH1 ELF2 ARL8B TGFBR2 MOB1B TRIB1 ANXA1 SH2B3 MOAP1 GPA33 PRKD3 FBXL3 DUSP11 ZMPSTE24 RPF1 SLC25A32 IL7R IKZF5 VCPKMT SLC25A33 PPIL4 CCNY DDX20 NOTCH1 MTMR9 FYTTD1 ATXN1L IFRD1 REL SNX9 ASTE1 ADNP2 PTP4A1 FOSB NAP1L5 SMCR8 IRS2 TAGAP CRY1 KANSL2 GEM IER5 IQSEC1 USPL1 CUL3 TTC19 DNAJB9 ZNF165 PUS3 ZNF326 SVIL CRBN ZFP36 TBC1D23 CD69 SPTY2D1 WDR47 DDX21 ITGA6 SECISBP2 HIVEP1	down	***
ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_DN	0.0034236	0.0323585	0.4317077	0.4167669	1.689941	71	TOX3 CDCA2 SLC26A8 ENAM SPATS2 SCG5 GFPT1 KIF15 MMS22L CCL28 SLC28A2 NCAPG2 NUSAP1 NSF POLE2 AAGAB SLC12A8 ANXA2R SLC26A2 TMEM237 KIF20B CEP128 IQUB UTP20 ZNF563 CFH USP39 TRAPPC9 RAB25 KDM5B TPM1 MBTD1 ST6GALNAC1	up	*
GO_REGULATION_OF_LEUKOCYTE_MEDIATED_CYTOTOXICITY	0.0055715	0.0463382	0.4070179	-0.3897297	-1.689818	56	CLEC12B CD1C LAMP1 IL23A DNASE1L3 SERPINB9 CRK CRTAM FAM49B CADM1 PTPRC IL7R CD160 TYROBP STX7 AP1G1 CD1D KLRC4-KLRK1 FCGRT ICAM1 IL18RAP ARRB2 HAVCR2 CD1E KLRK1	down	*
MORF_RRM1	0.0015396	0.0176112	0.4550599	0.4074491	1.689520	86	CENPF ESPL1 MCM2 TYMS ZWINT RUVBL2 NUDT1 CHAF1A BUB1 CCT5 PRKDC RAD54L KIF11 MCM3 DNAJC9 PARP1 SSBP1 GOT2 PMEL FEN1 SPAG5 DNMT1 DLGAP5 SNRPA LMNB2 SSRP1 MCM6 SRSF1 TXNL4A MSH2 VDAC1 SNRNP200 CHERP GPN1 SAFB CS XRCC5 NAE1 LRPPRC STMN1 PPM1G KHSRP BUB3	up	*
GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_UP	0.0000647	0.0013372	0.5384341	-0.3182413	-1.689327	178	KMO CD52 SASH1 ABHD5 DENND5A TAL1 OSBPL1A PTPRE RAMP2 LY86 LMO2 MYADM AQP9 CYB5R3 GIMAP6 EPB41L3 SH2B3 MAN2B1 BMP1 NAAA MAP3K8 IL18R1 GRN SPRY2 CYP4V2 RAB14 PTPN12 BNIP2 PLAUR ST3GAL2 STK17B KLF7 PLBD1 TMBIM1 ITGAX KLRD1 PRDM5 MAPRE2 HCK CTSS CABLES1 TYROBP APBB2 IRF8 SELENBP1 PRKCE SPOP DDHD2 CRYZL1 TSC22D1 CBFA2T3 GNB4 CD81 MEIS1 RGS2 GEM ICAM1 IL18 PIP4K2A ALDH6A1 S100A4 NFKBIA LTBP3 DNAJB9 THEMIS2	down	**
MIR4717_5P	0.0013123	0.0156911	0.4550599	-0.3565049	-1.688767	83	EPAS1 TRHDE GPR65 RAB3C FYN ERG ASAP1 SRSF2 ZEB1 ADIPOR2 PEAK1 BCLAF1 RBPJ GAS2L1 ST6GALNAC4 SERPINB6 FSD1L COL23A1 AGFG1 XYLT1 AKIRIN2 ATP6V1A PGGT1B FKBP1A KIF1B STARD13 CDC42BPB PAX5 PDE7B TES	down	*
GSE2706_R848_VS_LPS_8H_STIM_DC_DN	0.0000576	0.0012129	0.5573322	-0.3287759	-1.688515	142	RAB11FIP1 FOXF1 CPEB2 SNX10 LY86 PLEKHF2 GNPTAB EPB41L3 LATS2 ABCG1 STOM SLC25A37 TFEC BTG3 LINC00528 GPA33 KLF4 SPAG9 SNIP1 ERP44 C4orf33 PNRC1 PEAK1 N4BP1 RUFY3 HCAR3 CD80 DDX60L SAR1A HRH1 MAP4K4 GYPC OSM STX5 TNFRSF9 PELI1 GJA4 ICAM2 SRSF4 MFSD12 TCF7L1 UNC13D MIR155HG NBN TMOD2 TAB2 STK4 CYTH1 AIM2 NRP2 GRB10 GIMAP4 PMAIP1	down	**
GO_POSITIVE_REGULATION_OF_ENDOTHELIAL_CELL_PROLIFERATION	0.0008899	0.0116220	0.4772708	-0.3568496	-1.687648	85	ACVRL1 HMOX1 TEK GATA2 BMP2 CDH13 BMPR2 MIR27B MIR146A ADAM17 CAV2 NR4A1 AKT3 IL10 STAT5A NRARP TNFSF12	down	*
GO_CHROMOSOME_ORGANIZATION	0.0000000	0.0000000	0.8870750	0.3312142	1.687514	927	HMGA2 TRIP13 TP63 DDX11 HELLS FOXA3 EYA1 DDX12P HJURP STAG3L2 RUVBL1 CDC45 BUB1B NUP107 NEK2 EYA2 CCNB1 SOX2 CENPF POLQ PAGR1 KIF18B NDC80 PRIM2 PIF1 BRCA1 TTK GINS1 RACGAP1 CABIN1 KIF14 L3MBTL1 TSPYL5 DNMT3B POLE NABP2 MSTO1 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 WDR70 ESPL1 CDC6 SOX9 UHRF1 MCM4 PRKCA MCM2 RAD54B PRC1 MSL3P1 CCT6A MCM8 MIS18A GINS4 SRPK1 RCCD1 NCAPD2 ZWINT CDT1 CCT2 SPDL1 TOP3B RUVBL2 SDR16C5 SMARCD3 EXO1 SMARCC1 KIF23 STAG3 CHAF1A FOXA1 MKI67 BOD1 HLTF BUB1 TOP2A MAP10 CCT5 CENPL GPER1 AURKA NUP155 CBX3 REC8 POLA2 SYCP2 ATR POLD2 TPR SMARCAL1 KIF2C MCM7 MAD1L1 CENPW SMYD2 TTLL12 CDCA5 PRKDC TRRAP BRPF3 HELB SETDB1 RAD54L FANCD2 MCM3 CHAF1B HORMAD1 YEATS2 CHD6 BRD9 MORC2 ZNHIT1 CHEK1 NEK11 ACTL6A MAD2L1 FBL CENPO XRCC1 PIH1D1 PRMT6 DSCC1 BRIP1 HSF4 BLM PPP5C PHB PML NAA40 TADA2A ERCC2 MNAT1 RECQL5 PARP1 PSRC1 INCENP KNSTRN NCAPG2 TERC NUSAP1 ASF1B PAK1 ANAPC5 ING4 CDK1 WDR5B SSBP1 POLE2 RFWD3 CENPH CCT3 SUN1 DIS3L2 ZMIZ2 NAV2 NPM3 NCAPG DNA2 FEN1 EZH2 SPAG5 TAF6 TRAPPC12 PRKAA2 MAD2L2 VPS72 KLHL22 RECQL4 CENPP TEP1 KPNB1 L3MBTL3 DNMT1 TELO2 CCNE1 PABPC1L CDC23 TUBG1 DCLRE1C DLGAP5 TRIM16 SATB2 SMG5 MRGBP TACC3 KIF22 HIRA RAD51D HMGN3 MTA3 TRIM37 SUDS3 COPS7B FBXO4 CHTF18 CENPQ AKAP8L HDAC1 ESCO2 GINS2 ANP32E NOC2L LRWD1 PRMT7 SAP30 ANAPC1 CHD5 KDM3B POLD1 ESR1 COPS6 SLX4 ZBTB7B CCT7 RAD50 KDM3A ANKRD31 CENPK BAZ2A TADA3 EP400 SUPT16H STAG3L4 CENPV MEI1 PPHLN1 L3MBTL2 BRD8 CDC20 CENPM YLPM1 TWIST1 TUBG2 HMGA1 ALKBH4 RPA1 CHMP4C PELO CDK5RAP2 MCM6 KDM4B DNMT3A CHTF8 CENPT PRMT1 MCM5 USP21 ZRANB3 UIMC1 PYGO2 NSD1 NFE2 KATNB1 IGHMBP2 PRKD2 SMARCC2 ZNF274 ATAD2 PRMT5 NUP62 MSH4 SUV39H2 MCRS1 MSH2 CCNA2 SMARCA4 NTMT1 PRIM1 DTX3L BANF1 RTEL1 RFC5 ZNF462 INO80E MLLT6 RAD51 HLCS TNKS1BP1 BRMS1 CHMP1A NOS1 EYA4 SUPT3H PAXIP1 CHMP2A CHD3 CDK5 SIRT6 SMC2 PNKP LIF BCL6 XPC MAU2 CENPE SRCAP TP53 KDM5B APEX1 NCAPD3 PWP1 SMARCB1 ATF7IP DDB2 RRS1 NAT10 MUC1 RCBTB1 ZFPM1 SART3 ACTR5 SS18L1 SETD5 ERCC3 NCAPH ACIN1 PCGF6 POGZ INO80B CHMP6 SETD1A PCGF2 MBTD1 MLH3 MAP3K12 SPHK2 TOP3A METTL4 DFFB DSN1 HDAC10 HR RBL1 FBXO5 LCMT1 HUWE1 SAFB NSL1 EXOSC10 MECOM SMYD3 NHP2 RAG1 NPM1 CHD8 RNF8 DCLRE1B MSH6 RNF40 HMG20B WDR5 DQX1	up	***
REACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS	0.0042793	0.0381384	0.4070179	0.4277258	1.687141	62	IGLV3-27 IGKV1-17 IGKV3-15 IGKV3-11 IGKV1-16 IGKV4-1 IGKV2D-28 IGLV1-44 IGKV1-5 IGKV1D-33 IGHV3-48 IGLV1-40 IGHG1 PLCG1 IGLV7-43 ITPR3 IGLV6-57 IGLV1-47 PLD1 AHCYL1 IGKV1D-12	up	*
GO_IMMUNOGLOBULIN_PRODUCTION	0.0011648	0.0143218	0.4550599	0.3848578	1.686971	130	IGLV4-69 IGLV3-27 IGKV3D-15 IGKV1-17 IGKV2D-29 IGLV1-36 IGKV3-15 POLQ IGKV1-6 IGKV1-16 GCNT3 IGKV1-27 PMS2P5 IGLV3-9 IGKV4-1 GPI PMS2 IGKV2D-28 IGLV3-10 EXO1 CARD11 TP53BP1 POLM IGLV1-44 PRKDC IGKV1-5 IGKV2-24 IGKV1D-33 IGLV1-40 IGKV1-9 UNG MAD2L2 IGLV7-43 IGLV6-57 POLL IGLV1-47 POLB ATAD5	up	*
GO_ALPHA_BETA_T_CELL_ACTIVATION	0.0003209	0.0051543	0.4984931	-0.3359668	-1.686505	119	CD55 SPN TGFBR2 IL23A RHOA ANXA1 ADA FOXP1 HLX GATA3 IL18R1 MAPK8IP1 FUT7 SOCS5 PTPRC SMAD7 NCKAP1L CD80 IL6 CD160 PTGER4 CD83 GPR183 MALT1 RC3H1 AP3B1 TBX21 ZNF683 RUNX3 CD86 CD81 GPR18 IL18 SEMA4A RIPK2 NLRP3 ADORA2A RORA ZBTB16 TNFSF8 HMGB1 CD3E IRF1 RC3H2 IRF4 NFKBIZ EBI3 CBFB PNP	down	**
GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_DN	0.0001163	0.0021919	0.5384341	-0.3213338	-1.686502	165	CXCL3 ACE RASIP1 TIE1 PTPRE CCRL2 ST3GAL6 INPP5A SFR1 LMNA LIFR ACOT2 RNASE1 NR4A1 RGCC NDEL1 CD93 SPTBN1 SRGN SORBS1 PLAUR ID3 THBS1 LAPTM5 NFKB1 CXCL2 HOPX ACTR3 SS18L2 CMTM6 STK24 FOXN3 ETF1 CD80 AREG IL6 SOCS3 PABPC4 CEBPZ RALB NDST1 HIVEP2 SRSF6 MAPK8 FOSB EHD1 NAB1 STK40 SELPLG GPX3 SLC25A20 CD19 NFKBIA CYTH1 ZFAND2A	down	**
GO_REGULATION_OF_RNA_SPLICING	0.0007549	0.0102122	0.4772708	-0.3369878	-1.686104	110	PRX SRSF7 DYRK1A RBM7 TRA2B RBM4 SRSF2 CLK1 HNRNPU CWC22 AHNAK SRSF5 REST CLK4 SRSF3 CELF1 DDX17 WTAP PIK3R1 SMU1 DDX5 MBNL2 RBM22 CELF2 SRSF6 HNRNPA2B1 JMJD6 SRSF4 KHDRBS1 MAGOH MBNL1 HNRNPK NUP98 SRSF10 RPS13 THRAP3 HNRNPH1 ZNF326 YTHDC1 SETX RBMXL1 SAP18 FUS SNW1	down	*
MIR92B_3P	0.0000001	0.0000047	0.7049757	-0.2889602	-1.686054	410	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 NEDD4L BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 PRSS12 MED19 SLC7A11 GPBP1L1 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B NCKAP5 EFR3A AFF3 SNN LIN54 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 NOTCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 ZNF804A KBTBD8 MORC3 GRIA1 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 PIK3AP1 ZNF521 PHF3 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 IRS2 NFYC ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 ARPC2 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 MCOLN2 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 DUSP6 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 PIP5K1C MEF2D ZFYVE21 ITGA6 ROBO2 DOCK5 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1	down	***
VECCHI_GASTRIC_CANCER_EARLY_DN	0.0000052	0.0001626	0.6105269	-0.3034676	-1.685710	266	DAB1 SIDT2 TMEM100 SOSTDC1 ADTRP PGC FABP4 LYVE1 GREM2 CLDND1 PID1 ARRDC4 CGNL1 ST3GAL6 CITED2 MAL NR3C1 CD36 TMPRSS6 SSTR1 UBL3 MCTP1 SLC36A4 ADA LIFR C16orf89 LINC00261 GNG7 ADRB2 SFRP1 CNN1 EVI2B CYBRD1 PRDM16 C14orf132 PRKD3 KLF9 BCHE MYRIP ITIH5 GMPR AQP4 JAM2 CD302 PTGER3 VEPH1 AFF3 PDK4 TRGC2 FAM107A ID4 SYNPO2 MAGI2 NDNF RASSF10 RGS13 DUSP5 ZNF844 GABARAPL1 SCARA5 SBSPON IGKV1D-39 GPX3 SCN7A SEMA4A MFAP5 TTLL7 ALDH6A1 MT1M ZNF471 RBMS3 METTL7A GLUL KIT ABCA8 RORA NR3C2 KLF15 GHR CFL2 ZBTB16 ZNF385B ZNF677 MAMDC2 PIK3CG EBF1 MT1E LDB3 PLN SNRPN ADH1B CNTN1 CCPG1 ECHDC3 HSPB8 PLLP CYP1B1 SLC18A2 MT1X CHGA SETBP1 ZNF667-AS1 SLAMF7	down	***
GO_VACUOLE	0.0000000	0.0000000	0.8266573	-0.2749623	-1.685345	633	ACP5 RAMP3 SIDT2 PEBP4 MCOLN1 ACE TMEM150B IL1B MNDA CAT RAB44 SPNS1 LIPA RAMP2 THBD GPC5 PCSK9 CTSW CALCRL TMEM138 CHIT1 CYB5R3 ARL8B SLC15A3 CDC42 MANBA NCF2 CD1C VAPA FUCA1 LAMP1 CBL SLC11A1 HSPG2 ANXA1 SLC44A2 DNAJC3 MAN2B1 RRAGC SLC3A1 ADA RILP ARSB PCYOX1 ASAH1 NAAA GM2A IFI30 PRELP LITAF CYB561A3 ANPEP CLN5 ABHD6 STOM ADRB2 GRN LAMTOR3 SRGN ATP6V1H RAB14 ATP6V1B2 CYBRD1 FABP5 ARRB1 RAB12 PPT1 AHNAK SDCBP MEFV PEG3 SLC12A4 CDIP1 DAB2 GAA DRAM1 MAP1LC3B STX3 ATP6V1D TPP1 PLBD1 SPAG9 UBQLN1 CTSD TMBIM1 LAPTM5 CTBS C9orf72 HPSE ATP6V0D2 M6PR SFTPD TM6SF1 PRF1 WDR48 GCA HTT GNAQ HLA-DQA1 NRBF2 BACE1 LMBRD1 CMTM6 PI4K2A ACTR2 GLB1 HEXB HCK HGSNAT TBC1D5 PRCP TMEM9B CTSS GABARAPL2 PSEN1 SNAP23 VAT1 SFTPB CTSZ ATP6V0B ATP11A OSTM1 DNASE2 VPS26A TBC1D12 SNX2 STX7 GLIPR1 DAPK2 IDS ENTPD4 SNX1 CAP1 AP3B1 UVRAG CLN3 CST7 CD34 TMEM192 SLC3A2 ATP6V0D1 CD164 NAPG CD74 SORT1 AP1G1 CD1D MILR1 VAMP4 SBF2 MTMR2 TMEM230 GNAI1 ATP6V1A IFNAR1 PIK3C3 GALC ATP6V0C GNB4 GABARAPL1 ORM2 BRI3 VPS39 MFSD12 CLCN6 PLA2G15 IST1 SYT11 UNC13D CPQ LAT BLOC1S2 PIP4K2A CXCR4 HSP90AA1 CALCOCO2 GIMAP5 HSPA8 NHLRC3 KIT CTSC CD1E SNAP29 MMD ANXA11 LDLR CREG1 WDFY3 RNF13 RAB2A LYZ SMPD1 FNBP1 ZFYVE26 EPG5 ATP6V0A1 USP4 CTSH SPPL2A TMEM30A KCNE1 ATP11B LNPEP MAPK1 FTL SH3GLB1 NCF1 RB1CC1 RAB37 ZFYVE1 DRAM2 FPR1 SLC26A11 NFAM1 PIK3CG YWHAB VPS36 WDR41 LAMP3 SNX14 HLA-DRB1 LAMTOR5	down	***
GO_DAMAGED_DNA_BINDING	0.0044868	0.0394933	0.4070179	0.4271714	1.684954	62	TP63 POLQ BRCA1 RBBP8 TP53BP1 AUNIP XRCC1 RAD18 BLM ERCC2 UNG NEIL3 FEN1 RECQL4 FANCG DCLRE1C POLD1 POLB RPA1 MSH2 PNKP XPC MPG NEIL1 APEX1 RAD1 DDB2 ERCC3 DCLRE1B MSH6 DCLRE1A POT1 XRCC5 XRCC6 MSH3	up	*
GO_AMYLOID_BETA_BINDING	0.0052326	0.0442349	0.4070179	-0.3742171	-1.684779	63	RAMP3 COL25A1 MARCO HSPG2 CD36 PICALM FZD4 ADRB2 CST3 MSR1 ITM2B BCHE TLR4 BACE1 TGFB2 C1QA APBB2 GRIA1 CD74 GSAP FPR2 APBB1 EPHA4 DLGAP3 LDLR	down	*
GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS	0.0007253	0.0098961	0.4772708	0.3847898	1.684704	127	HKDC1 ENTPD2 AK4 NUP107 PGM2L1 DDIT4 GPI GAPDH ALDOC AK8 NME1 DLG1 CARD11 NUP155 TPR NME9 PKM NME5 PFKP ALDOA ENTPD5 GCKR LRGUK ALDOB BPGM NUP205 AK7 PRKAA2 EIF6 FOXK1 DTYMK NUDT16 NUP85 DHTKD1 ENTPD8 AAAS ENTPD3 BAD PFKFB4 ESRRB NUP62 NME4 HK2 SEC13 PFKM NME7 PGAM1 SIRT6 ENO1 NUP210 NUP93 PRKAG1	up	**
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN	0.0004356	0.0065735	0.4984931	0.3743619	1.684696	162	FOXM1 MCM10 PROM1 CCNB1 POLE PTTG1 PAK6 CDC6 TPX2 NNT CCNB2 MCM4 MCM2 TYMS CCNF RANBP1 WDR62 HMMR EXO1 KIF23 CHAF1A MKI67 WASF1 KIF2C RRM2 RHOBTB3 CDC25C SIDT1 CHEK1 MAD2L1 INPP4B IDH2 CKS1B CDKN2C TMEM106C POLE2 BIRC5 TESC MECR SRD5A1 TUBG1 DLGAP5 HMGN3 TK1 DTYMK RHD POLD1 CDC20 CENPM RPA1 CORO2A CCNA2 SHCBP1 BLVRB INSL3 TRIB2 MTHFD1 DHRS3 GPX7 UBE2C NUP210 HGF NCAPH CD38	up	**
MODULE_139	0.0039394	0.0358546	0.4070179	0.4147146	1.684649	73	MNX1 PRLR BDH1 PRR15L AGR2 SPINT2 SYT12 TJP3 SYTL2 FOXA1 MSX2 ICA1 SLC9A3R1 B3GNT3 KRT18 TNFRSF25 ARHGEF16 PKP3 MSI2 KRT19 ERBB3 UBXN6 KRT8 ANXA9 EPCAM CDH1 BLVRB	up	*
MIR1202	0.0043771	0.0387674	0.4070179	-0.3841588	-1.684075	57	OSBPL11 LRRC8C CDH5 ZBTB34 CNST LUZP1 ZNF365 LRP4 DENND6A CLIC4 SHE ZBTB43 EGLN2 CDK14 RRN3 BCL6B PSMD12 SYPL2 NR2C1 ZDHHC21 PAK2 TMEM87A	down	*
GSE19198_1H_VS_24H_IL21_TREATED_TCELL_DN	0.0000803	0.0016093	0.5384341	-0.3171479	-1.683690	174	SLC24A4 PTPRE EGR2 CD44 WDR74 RASAL2 SRSF7 NCF2 GALNT18 LRRFIP2 HBEGF DNAJC5B LITAF TTYH2 SLC7A11 ZFYVE16 SRGN BTG3 TUBB6 TAPT1 TBC1D9 ADO PLBD1 PAPSS1 ATP6V0D2 ARAP3 PLEK PLCD1 NRROS ARL6IP5 BCAR3 SNAP23 CD48 HK3 CCR7 CD83 LGALS2 OCIAD1 CDK14 CR1 EHD1 PEA15 CD86 KYNU MOB3B RIPK2 TRAF1 PLGRKT TIMP3 ANXA11 C1orf115 PMAIP1 RAP1GAP AFTPH CSF2RB MB21D2 SVIL ITGAL TBC1D23 TUBA1A ATP1B1 NFAM1 PTGS1 ZBTB46 SLC25A45 FCHSD2 CYTL1 NR4A3 MSC PPP1R14A SLC29A3 CYP1B1	down	**
chr12q13	0.0001071	0.0020529	0.5384341	0.3650213	1.683523	199	KRT5 NXPH4 TROAP GALNT6 TIMELESS DNAJC22 ASIC1 RACGAP1 IGFBP6 NABP2 ESPL1 B4GALNT1 SPATS2 DTX3 PIP4K2C SHMT2 SMUG1 MYL6B DCTN2 SLC4A8 SMAGP METTL7B GPR182 ANKRD52 HOXC6 WNT1 BLOC1S1 LETMD1 CSRNP2 SNORA2A TFCP2 R3HDM2 CNPY2 SLC39A5 MYO1A TMEM106C CBX5 KRT18 KIF5A STAT2 PMEL FAM186A ACVR1B PA2G4 KCNH3 OR10AD1 SCN8A OS9 BCDIN3D-AS1 BAZ2A RDH16 LIMA1 DGKA ORMDL2 ERBB3 AAAS MIR4698 WNT10B KRT8 DDX23 STAC3 CACNB3 NFE2 SUOX SMARCC2 COPZ1 MCRS1 RPS26 PRIM1 STAT6 PFKM IKZF4 DIP2B TARBP2 ADCY6 DNAJC14 OR5BK1P SLC38A4 KRT80 TUBA1C C12orf10 PRKAG1	up	**
GSE17974_0H_VS_0.5H_IN_VITRO_ACT_CD4_TCELL_DN	0.0001412	0.0025672	0.5188481	-0.3264169	-1.683504	148	OSBPL1A TMEM126A GPR65 GLTPD2 EGR2 IBA57 IDI1 PRPF38A BCL2A1 PPM1D IER2 PKHD1L1 RAPGEF4 BTG2 KLF10 ZNF410 PRSS12 ZBTB8A NR4A1 NFE2L2 SPI1 EVI2A MIR17HG RASGEF1B AREG CREM CRNKL1 ETV3 ARL5B HPGDS IFRD1 PNPLA8 GPR183 NUDT15 NAA30 HSF5 TEX30 CNTNAP1 TAGAP LEKR1 GPR18 GEM EXOC2 SLC31A1 TXNDC15 IER5 DCTN4 FBXO30 USH2A DNAJB9 DOCK4 EGR1 CFL2 LRRC63 NR4A2 ICOS YRDC CD69 ANKHD1 TRMT10C NR4A3 YOD1 ZNF331 DUSP2 FBXL13	down	**
LEE_DIFFERENTIATING_T_LYMPHOCYTE	0.0000811	0.0016202	0.5384341	-0.3170795	-1.683327	174	CD52 KLF13 LPXN SRSF7 MAL ATF7IP2 TXNIP EIF4A1 BTG2 PAG1 GATA3 RGCC FLI1 EVI2B HAUS2 MGAT4A LAPTM5 PTPRC SELL ARHGAP9 CD53 EVI2A IL7R CNOT6L ARHGDIB BTG1 NCKAP1L TRGC2 RYBP AQP3 CD48 GIMAP2 RAC2 GMFG DOCK8 CELF2 OCIAD1 ICAM2 SRSF6 ING3 CCDC152 TAGAP MR1 SELPLG LAT TNFAIP8 CXCR4 CD3G CYTH1 FGFR1 CCND3 SFPQ SPATA13 FNBP1 LNPEP PRKCH ICOS ITGAL KMT2E PIK3CG RCSD1 STX16 ATP8A1 TRAT1 AKAP13 ARHGAP30 FAM107B RASSF5 PNISR TMEM71 CBX4 ITK DOCK2 HCLS1 CD3D BCL2L11 APBB1IP METAP2 SNX20	down	**
GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP	0.0001326	0.0024429	0.5188481	-0.3198513	-1.682990	168	SC5D KLF13 SIK1 FYN HSD17B11 ELF2 PLEKHA1 S1PR1 TGFBR2 IER2 KIAA0355 DPEP2 BTG2 RNF125 LITAF CLK1 PPP3CC ARRB1 FOXO1 SRSF5 BNIP2 GPA33 ITM2B PSPN COQ10B LEPROTL1 ARNTL MGAT4A SMAD7 BRF2 PIAS1 ID4 CD48 DNASE2 WTAP PTGER4 PIK3R1 GYPC HIVEP2 CD6 CDC37L1 TSPAN14 TOB1 ACYP2 KANSL2 KAT2B PDE4B EPN2 CXCR4 OSER1 ICAM3 JMJD1C CYTH1 DAZAP2 IL16 ZBTB40 SMPD1 ARHGEF18 ACSM5	down	**
MIR92A_3P	0.0000000	0.0000024	0.7195128	-0.2888299	-1.682872	413	SOSTDC1 SGK3 GATA2 CPEB2 ATXN3 MBOAT2 RAB3C INSIG1 ARRDC4 KIAA1109 NEDD4L BMPR2 SLC39A8 PLEKHA1 PCOLCE2 TET2 OTUD4 TEX2 ZEB2 EDEM1 ZNF385D LATS2 MTF1 ITGA5 BTG2 RANBP9 LUZP1 HIPK3 PRSS12 MED19 SLC7A11 GPBP1L1 ADRB1 MCL1 RAB14 ATP6V1B2 MSR1 MOAP1 AGO3 NPNT PTPRO KLF4 REST MYO1B ZNF24 PER2 DOCK9 TEF PLEKHB2 SLC25A32 PEAK1 GNAQ UBASH3B AFF1 NCKAP5 EFR3A AFF3 SNN LIN54 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 RAB8B PIKFYVE LRCH1 NOTCH1 CPEB4 C20orf194 FOXN2 MTMR9 APBB2 TBC1D12 PTGER4 ZNF804A KBTBD8 MORC3 GRIA1 SLC10A7 PDZD2 CXCL5 GFPT2 EPC2 CELF2 CTTNBP2 KLF2 MAPK8 PIK3AP1 ZNF521 PHF3 TGIF1 BAZ2B ABHD13 DUSP5 CBFA2T3 MIA3 IRS2 NFYC ATXN1 GLRA1 TAGAP TOB1 GATA6 KAT2B ADAM10 PHLPP2 PITPNA MIER1 ARPC2 FKBP1A VPS4B TOB2 G3BP2 FNBP4 LIMCH1 ZDHHC5 RNF38 ST6GAL2 FNIP2 PTEN LYST DNAJB9 MCOLN2 FAM126B MMD C21orf91 RORA NRG1 EVI5 TRIM36 PAPSS2 EPG5 ARHGEF17 DUSP6 ADAMTSL1 HIPK1 LHFPL2 SLC38A2 PLXDC2 ADAMTSL3 COX20 CD69 C6orf62 UBE2W FAM160B1 SCAF11 SGPP1 RAD21 PAXBP1 PIP5K1C MEF2D ZFYVE21 ITGA6 ROBO2 DOCK5 USP45 FNIP1 GNPDA2 NR4A3 CCNC HIVEP1	down	***
KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY	0.0018836	0.0204249	0.4550599	-0.3715236	-1.682618	67	CD22 NFATC3 LILRB3 PPP3CA AKT3 PPP3CC NFKB1 PIK3R5 JUN RAC2 PIK3R1 GRB2 MALT1 PLCG2 FOS PIK3AP1 VAV3 PPP3R1 CD81 CD19 NFKBIA CHP1 MAPK1 PIK3CG CD79B DAPP1 BCL10 SOS2 RASGRP3 PIK3R3 NRAS	down	*
GO_INOSITOL_1_3_4_5_TETRAKISPHOSPHATE_BINDING	0.0057153	0.0472245	0.4070179	0.8363574	1.682490	5	ASTN2 SYT2 ADAP1 ITPR3	up	*
TURASHVILI_BREAST_NORMAL_DUCTAL_VS_LOBULAR_DN	0.0057806	0.0475954	0.4070179	0.8362189	1.682212	5	ZNF117 RHOBTB3 EHBP1 TSPAN5	up	*
GO_HETEROTYPIC_CELL_CELL_ADHESION	0.0061320	0.0497847	0.4070179	-0.3939730	-1.681506	51	IL1B IZUMO1 CD44 MYADM IL1RN ITGA5 JAM3 SIRPA CD58 GLDN IL10 KLF4 ITGAX PTPRC	down	*
GO_BLOOD_MICROPARTICLE	0.0018859	0.0204410	0.4550599	0.4037695	1.681504	89	TF HP FGA IGKV1-17 HBA1 CP HBA2 IGKV3-15 CIB2 SLC2A1 IGKV4-1 HBB IGKV2D-28 APOL1 AGT FGG SERPINA3 OAZ3 HPR IGKV1-5 IGKV1D-33 PON1	up	*
GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN	0.0001717	0.0030221	0.5188481	0.3728083	1.681448	168	FOXM1 KCNK5 BDH1 NUP107 CCNB1 POLQ PAGR1 ANKZF1 TRAIP TRIB3 UHRF1 EXOC3 RCCD1 ASTN2 KCNN4 EMC9 PAFAH1B3 FANCA EME1 NDUFS2 LETMD1 SARS2 EHHADH BRIP1 GNPDA1 GLE1 MEOX1 NUDT2 UNG ZNF775 MECR COA4 ETFB DIAPH3 QPRT RNASEH2A PSMA5 LMNB2 RAD51D FBXO4 FUCA2 GEMIN6 TADA3 DHRS1 LINC00467 HMGA1 RABEPK CACNB3 FBXO36 MRPL51 CCNG1 HAUS4 GLO1 PFKM ZSCAN22 GBP2 ETHE1 SNUPN KDM5B NCAPD3 ENO1 PRKAG1 NCAPH CYB5B HEXIM2 TRAFD1 MRPL12 CBLN3 MSH6 DHX32 STXBP1 CDPF1 SHMT1 KEAP1 TXN2 POLD3 METTL9 STMN1 COA6 RMI2 SKA3 SLC29A1 MRPL35 AJUBA	up	**
GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_UP	0.0000243	0.0005895	0.5756103	-0.3186321	-1.681163	171	CXCL3 EREG EDNRB TBX3 RBMS2 CPEB2 FIG4 PPP4R1 CCRL2 MTMR10 TRIB1 SEMA6D PKHD1L1 LITAF PTX3 TOR1AIP1 CD93 TUBB6 IL10 FOXO1 DGKE NPNT KLF4 PLAUR DAB2 ZFAND5 CXCL2 CCL4 N4BP1 HLA-DQA1 TULP2 SOCS3 OASL ETV3 SLC14A1 KCTD12 ARHGEF10 RHOJ RCAN1 PRKCE REL CLN3 FOS EPPK1 RIN2 PIK3AP1 SAV1 PDLIM1 BMP2K GEM FGF2 B3GALNT1 TIAM1 TDRP TBC1D1 ING2 EDN1 EPB41L4A CYTH1 THEMIS2 MT2A ZBTB44 RABGEF1	down	***
GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_DN	0.0001117	0.0021208	0.5384341	-0.3229896	-1.680729	159	SIRPB1 RAB11FIP1 CXCL3 SLC31A2 ACP5 OLR1 ZC3H12C IL1B SNX10 NUP54 TMEM170B HCAR2 RGS9 MS4A15 CDC42EP2 BCL2A1 PILRA HDC SLC7A11 BNIPL TFEC NODAL PTPN12 CCL22 MEFV REST VASP KLF7 CCL4 PLEK N4BP1 FAM102B HCK KANK1 SOCS3 SERPINB8 NXPE3 FOXN2 UBAC2 ACSL1 RHOQ SMPDL3B EHD1 GSAP SOD2 PDE4B ETS2 SLC34A2 SEMA4A CEBPD USPL1 NLRP3 TRAF1 NFKBIA ADORA2A ZDHHC5 SAMSN1	down	**
GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP	0.0004049	0.0062201	0.4984931	0.3715946	1.680045	174	MEGF10 TROAP BUB1B ANKFN1 CENPF PBK KIF18B RACGAP1 IQGAP3 DGCR8 PLK1 NUF2 NNT CCNB2 CCNF XPO5 MIS18A FSTL4 SLC4A8 TAMM41 MKI67 PCCB COPG1 KIF2C MCM7 KIF11 FANCD2 TRMT2A CAD IPO9 BLM IDH2 WWC1 PARP1 CMAS ANAPC5 PEG10 POC1B NOP2 DNMT1 INTS7 DLGAP5 C19orf44 ADAM12 SND1 NRF1 NADSYN1 L3MBTL2 KDELR3 TMEM106B BEND6 NOL6 WDR35 CLUH PRODH RAB34 CDC42BPA SHCBP1 NAV1 RAD51 R3HDM4	up	**
GSE24726_WT_VS_E2_2_KO_PDC_DAY4_POST_DELETION_UP	0.0000492	0.0010676	0.5573322	-0.3159437	-1.679866	175	SLC31A2 KMO SC5D PECAM1 LRRC8C C18orf32 RAPGEF2 CLDND1 AKAP7 CDC42EP2 NR3C1 LAMP1 AGPAT4 SLC11A1 DNAJC3 COQ7 PAG1 CLN5 NFE2L2 SPRY2 TFEC MTHFR FABP5 MAFG RMDN3 PLBD1 IRAK2 C9orf72 HPSE RAP1GDS1 HLA-DQA1 MMP19 LACC1 NINJ1 METAP1 VPS37A DDHD1 JUN USO1 PSTPIP2 HSD17B12 HOMER1 NOP10 CD74 CDC37L1 IFNAR1 DYNC1LI1 STK40 TSPO SEMA4A CEBPD FBXO30 CEPT1 SAMSN1 NRP2 CCND3	down	**
NAKAMURA_ADIPOGENESIS_LATE_UP	0.0010105	0.0128301	0.4550599	-0.3499762	-1.679628	91	PPARG FABP4 INSIG1 CCRL2 MYADM CDH13 TGFBR3 GAS6 CD36 GM2A SERPINB9 STOM CYBRD1 FOXO1 STX3 ZNF24 SIK2 ATF3 ELK3 PPP2R5A TGFB2 RAB31 CCDC50 PLK3 XYLT1 TGFB1 IRS2 RAB5A CEBPD ACACB MMD SMPD1 USP4 HMGCS1 MAPK1	down	*
MIR570_3P	0.0000000	0.0000000	0.8140358	-0.2735946	-1.679562	635	SEMA6A SC5D COL25A1 TUBD1 TBX3 LRRC8C ATXN3 SNX10 PTPRE LIPA TMEM170B EMCN PPP4R1 SEC22C BAG4 MYADM NEDD4L QKI PAFAH1B2 KBTBD3 KCNN3 FBXO3 NR3C1 CD1C C3orf70 FAM49A DDO TMX4 STARD4 LACTB PTS TRA2B B3GNT5 CYYR1 RNF182 CAV2 CAMTA1 SLC7A11 PEX5L DACH1 SPRY2 HNRNPU GPM6A PTPN12 CWC22 TBC1D9 C14orf132 AGO3 BNIP2 PPP6R3 LIMS1 ACSL3 SLC38A11 HAUS2 PLEKHM3 ZFAND5 MYO1B ABCC4 SPAG9 MGAT4A UBE2E2 EPGN CDS2 C9orf72 ATP6V0D2 FRMD4A PLEKHB2 PIK3C2A WDR48 RAP1GDS1 KBTBD4 PAFAH1B1 BCLAF1 KPNA3 PDE1C CALM2 CRIM1 MARK3 EFR3A LIN7A LMOD3 RPS6KA2 SNX3 SERTAD2 GPBP1 SPIN1 MOB4 RBPJ SLC8A1 DCP1A PPP2CA METAP1 ELF1 FAM189A1 PDIK1L YBX1 NEK7 SNAP23 APPL1 UTRN SRSF3 ARL5B GABPA DDX17 BMP3 APBB2 AK1 HSPA13 SMU1 DDX5 MBNL2 CREB1 KBTBD8 COBLL1 RC3H1 ZBTB24 ATP13A3 TPP2 TRAK2 THSD7B OGFRL1 YWHAZ CGGBP1 ZCCHC9 ZNF407 CDK14 MORF4L1 ADNP2 CTTNBP2 YPEL2 CD164 YTHDF3 PSMD12 SRSF6 SLC35F1 XYLT1 EPHA3 PBRM1 STRN KIAA0232 PDS5B TEX14 HECW1 VAMP4 GNAI1 IRS2 TPMT CNOT7 ORC2 COL15A1 HNRNPH3 PPIG MYOCD ODF3 CLASP2 GNA13 KAT2B ADAM10 IST1 CCNH INO80D HELZ JUND ABL2 ARPC2 FKBP1A C22orf23 SCN7A MGAT2 DCTN4 RTN4 LRP12 FBXO30 DIXDC1 PTCH1 KPNA4 RBMS3 SREBF2 STAM2 HNRNPC CUL3 SCAI FNIP2 C20orf203 FAM126B PRKG1 SAMSN1 C21orf91 TMCC3 RORA FAM13C DAZAP2 GRB10 TLK1 EHD4 PURB MACROD2 ZBTB44 EIF4G2 PPP1CB DCUN1D2 ZNF326 MAP4 PSIP1	down	***
LI_INDUCED_T_TO_NATURAL_KILLER_UP	0.0000010	0.0000383	0.6435518	-0.3042084	-1.679405	275	CD52 GPR15 SCIMP HVCN1 HHEX GLIPR2 TMEM126A LRRC8C CLDND1 CTSW GFOD1 ST3GAL6 CORO1C AQP9 STX11 CD9 KLHL30 ARSB LMNA ASAH1 C1orf21 SERP2 EMILIN2 IFI30 LITAF IL18R1 PDGFA TUBB6 PPP3CC AHNAK CASP1 MED11 OSTF1 DENND3 CCL3 NFKB1 CDKN1A COTL1 RBMS1 IRAK2 VIM HOPX ID2 CCND2 ARAP3 FCER1G EVI2A KLRD1 ARL6IP5 CD160 SGK1 TYROBP JUNB STX7 GLIPR1 DAPK2 OSM SERPINB6 CD7 TNFRSF9 DENND4A PLCG2 MFSD10 MSMO1 NKG7 PEA15 KCTD10 DUSP5 LGALS3 DOK2 GPR18 PLEKHO2 ZNF296 TSPO VASH1 SERTAD1 ELOVL1 SEMA4A TIAM1 LRP12 CYB5R4 SEC61B ITGAE HAVCR2 TRAF1 S100A4 KIT EHD4 FNBP1 PIM3 EGR1 DUSP6 SH3BGRL3 HMGCS1 CAPZB ENDOD1 CX3CR1 SLC19A2 FTL NDFIP1 MT1E CD69 CYP51A1 FXYD5	down	***
GO_NEGATIVE_REGULATION_OF_LOCOMOTION	0.0000010	0.0000389	0.6435518	-0.3041976	-1.679345	275	ANGPT4 SEMA6B SEMA3G SEMA6A ACVRL1 HMOX1 DLC1 PPARG ADTRP TIE1 WNT4 ENG CORO1C CITED2 TBXA2R TRIB1 RHOA APOD SEMA6D MIR146A MMRN2 PTPRM MCTP1 SEMA3B ADA ADIPOR1 ABHD6 DACH1 GATA3 RGCC NFE2L2 CRK SFRP1 WNT3A NODAL RHOB ADARB1 DUSP3 PTPRO KLF4 THBS1 ADAMTS9 CLDN5 CLIC4 MIR24-2 RECK DUSP1 SMAD7 TBX5 IL24 ARHGDIB STK24 GNRH1 SRF SRGAP2C KANK1 PODN MAGI2 MITF LRCH1 NOTCH1 PTGER4 RRAS FOXO3 EPPK1 CD74 WNT11 TGFB1 CYGB MIA3 KLRC4-KLRK1 MYOCD CLASP2 GPR18 LDLRAD4 FGF2 VASH1 CHMP3 SEMA4A SP100 LIMCH1 ADORA2A SCAI KLRK1 PTEN PRKG1 NRG1 STARD13 ACVR1C GREM1 SERPINE1 C5AR2 CX3CR1 C5 PIP5KL1 NOG MIR640 MIR2355 CALR WNT5A ANGPT2 TRIM13 HMGB1	down	***
GSE7509_DC_VS_MONOCYTE_DN	0.0000247	0.0005953	0.5756103	-0.3182613	-1.679206	171	CXCL3 SLPI ACP5 OLR1 SNX10 CCRL2 AQP9 PRPF38A MARCO MOB1B FGR IER2 RHOA ADA SLC7A7 RAB33B CYB5A ABCG1 SLC7A11 MS4A1 RGCC SPI1 TXN RHOB PTGIR KLF4 KLF7 CLIC4 MARVELD1 CD302 INHBA CPT1A HLA-DQA1 TANC1 HCK PROCR PSEN1 GMFG FSTL3 ACSL1 KRTCAP2 KLF2 ECI2 SRSF6 FPR2 NAB1 SOD2 MAGOH PLAA TSPO ETS2 CCR6 TRAF1 NFKBIA EPB41L4A C1orf52 GIMAP4 ATF4 SMPD1 RAP1GAP FKBP1B CLEC4E S100A8 FPR1	down	***
GO_MALE_GAMETE_GENERATION	0.0000036	0.0001153	0.6272567	0.3478826	1.679179	344	TSPAN8 TRIP13 TP63 SPATA24 SPATA25 MYCBPAP FOXA3 RUVBL1 PMFBP1 CCNB1 WFDC2 DPY19L2P1 GAL3ST1 CREB3L4 RACGAP1 CATSPERB SLC26A8 ASPM TTC26 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 SPINK1 CIB1 TDRKH MCM8 SRPK1 RSPH1 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA REC8 ODF2 SYCP2 POC1A DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 HORMAD1 CDC25C NME5 OAZ3 HSF2BP BRIP1 SPAG8 CCDC136 MEA1 ASF1B LRGUK MERTK SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 GOLGA3 FANCG CATSPERG CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 CTSV MNS1 ADAM28 IQCG MORN2 PCSK4 TSSK3 SPA17 SPATA32 SLC4A2 CHD5 TYRO3 KDM3A MEI1 ROPN1B BCL2L1 CATSPER2 BAD DNMT3A RAI14 GGT3P DPY19L2 PYGO2 GGT5 PHC2 PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1	up	***
MORF_FANCG	0.0003062	0.0049783	0.4984931	0.3790682	1.678599	144	DDX11 SLC2A1 ECE2 SLC4A3 RBBP8 CCNF PVT1 HAUS5 WDR62 MKI67 BPHL CARD10 TPR MSX1 ERAL1 CDC25C PKMYT1 HSF4 FDXR PPP5C PHB PML ERCC2 MEA1 PPIL2 DNA2 OARD1 TTI1 ZNF500 DNAJC7 FANCG SPEF1 KDM3B CDK13 SH2B1 TSTA3 CPSF4 SRRT TFAP4 NUP62 NFRKB ACKR2 BMS1 PAXIP1 RPRD2 CHD3 ADAM15 PWP1 PLIN3 ILVBL MOK PRKAG1 GRIP2 XPO6 PCGF2	up	**
FEVR_CTNNB1_TARGETS_DN	0.0000001	0.0000068	0.6901325	0.3396269	1.678405	476	HMGA2 TRIP13 FOXM1 SPATA24 HELLS EPHB3 KIF20A RUVBL1 CHEK2 BUB1B HBA2 ADRA2A TIMELESS PRIM2 BRCA1 PHGDH TTK GINS1 ZFP62 RACGAP1 TRAIP GMPS POLE NUF2 AURKB ECT2 CDC6 SOX9 NNT CCNB2 FIGNL1 MCM4 MCM2 TYMS PRC1 HBB NCAPD2 CDT1 CCT2 LSM5 CYP3A5 C5orf34 MELK EXO1 KIF23 KCNN4 MKI67 CARD11 KNTC1 BUB1 TOP2A CCT5 CENPL NUP155 POLD2 MCM7 CD2AP CENPW RRM2 SMYD2 RHOBTB3 ZNHIT6 RAD54L MRPL3 MCM3 CHAF1B CDC25C SOX4 SMYD5 EGFR LIG1 CHEK1 ORC6 FBL CENPO PFKP RAD51AP1 DSCC1 EHF EEFSEC SKP2 GEMIN4 INCENP KNSTRN CBX5 ASF1B ANAPC5 CDK1 HDGF POLE2 KCNE3 CENPH BIRC5 CCT3 AAGAB E2F1 UNG GJB3 GNPNAT1 ENPP3 FEN1 EZH2 SPAG5 LIPT2 MTBP CBX1 DIAPH3 CENPP PA2G4 DNMT1 VBP1 NINL NMRAL1 KIF22 EPHB2 TRIM37 SSRP1 DTYMK CHTF18 MSI2 POLD1 POLB CDC7 CENPK CDC20 KIAA0100 AHCYL1 LIPG FAM136A RPA1 MCM6 CKAP2 MCM5 CAPRIN2 SNRPD1 HAUS6 ADD3 SRSF1 CUBN LRIG1 GTPBP10 NUP62 PMS1 MSH2 CCNA2 PRIM1 SHCBP1 RAD51 TRIP6 ARHGAP5 SCOC ERGIC1 ACP1 SLC12A2 POLR1B CENPE SMPD4 MTHFD1 PAICS FGFBP1 APEX1 TTC30B EPHB4 PNN NUP210 RAD1 RRS1	up	***
REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	0.0003028	0.0049293	0.4984931	0.3730257	1.678255	164	BUB1B NUP107 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 CDCA5 MAD2L1 PSMD4 CENPO SPC24 INCENP ANAPC5 CENPH BIRC5 PSMB5 KIF2A ANAPC7 DYNLL2 PSMC4 CENPP RANGAP1 CDC23 PSMA5 TUBB2A PSME2 TUBA3D TUBA8 CENPQ ANAPC1 PSMD2 NUP85 CENPK CKAP5 PSMB3 CDC20 CENPM DYNC1LI2 CENPT	up	**
GO_POSITIVE_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	0.0013453	0.0160042	0.4550599	-0.3601548	-1.677665	78	IL1B CD1C LAMP1 IL23A CLCF1 GATA3 IL18R1 TRAF6 CRTAM TFRC FAM49B CADM1 PTPRC FCER1G IL6 CD160 STX7 MALT1 TBX21 TNFSF13 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT IL18 IL18RAP NLRP3 CD1E KLRK1	down	*
GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP	0.0000251	0.0006033	0.5756103	-0.3179633	-1.677634	171	SC5D ADCY9 CTSW ST3GAL6 MAL LAMP1 TGFBR2 TXNIP HBEGF ADA BTG2 HNRNPDL SORBS3 TIPARP CCNI SDCBP BNIP2 LEPROTL1 STX3 SPAG9 UBE2B PER1 RNF139 IL7R PLCD1 FOXN3 BTG1 RBM39 AREG CREM SGK1 JUNB PPP1R15A CCR7 SNRK SRSF6 GABARAPL1 FCGRT CLEC2B PDE4B JUND RBL2 TPT1 RPS13 CYTH1 FGFR1 DAZAP2 MT2A EIF4A2	down	***
MODULE_223	0.0016417	0.0184340	0.4550599	-0.3318863	-1.677194	113	EREG IL1A IL1B EMP2 INSIG1 LY86 FOSL1 ADRA1D GAS6 LILRB3 CD8A DNAJC3 CD5 HBEGF KLF6 GRN ZEB1 MTHFR PDGFA DAB2 SELL SELP EVI2A BTG1 EMP3 CD8B AREG IL6 CD48 CD83 OSM CXCL5	down	*
chr7q11	0.0051611	0.0438904	0.4070179	0.4251196	1.676861	62	STAG3L2 ZNF273 ZP3 ZNF138 PMS2P5 SKP1P1 ZNF117 ERV3-1 ZNF107 PMS2P4 LINC00174 DTX2P1 KCTD7 TYW1 SNORA22 FDPSP7 DTX2 UPK3BP1 CCDC146 STAG3L4	up	*
GO_PROTEIN_TRANSPORT_ALONG_MICROTUBULE	0.0055542	0.0462664	0.4070179	0.4255789	1.676549	61	KIF1A IFT122 TTC26 IFT27 KIF3B IFT43 WDR60 IFT172 KIF3C KIF5A SSX2IP DYNLL2 LCA5 IFT52 TRAF3IP1 WDR34 WDR35 DYNC2H1 ICK CLUAP1 MAPK8IP3 CAMSAP3 TTC30B MAK KIFAP3 BBS12 KIF3A IFT81 IFT74 TCTEX1D2 DLG2 SSNA1 IFT80 TTC30A LCA5L TUB	up	*
GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	0.0021006	0.0222599	0.4317077	0.4067371	1.676465	82	HMGA2 DDX11 FOXM1 EYA1 EYA2 TIMELESS BRCA1 NPAS2 EEF1E1 ATR MSX1 PRKDC EGFR XRCC1 PLA2R1 PARP1 MAD2L2 RAD9A MGMT NUDT16 PARP9 UBE2V2 ANKRD1 UIMC1 DTX3L EYA4 PAXIP1 PIAS4 TMEM161A SPIDR HDAC10 SPRED3	up	*
GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN	0.0001429	0.0025874	0.5188481	-0.3193689	-1.676189	165	DNAH17 DLC1 HHEX FABP4 MNDA FBP1 DCSTAMP LPXN GPR65 LIPA GFOD1 RASAL2 LINC00622 NCF2 AVPI1 TXNIP CD36 NCEH1 CLEC7A RGCC KIAA0513 ADO KLF9 MAP1LC3B PAPSS1 TM6SF1 RAP1GDS1 UBASH3B CD300LB MRVI1 PRCP RBPJ PGD OASL MITF CPEB4 TREM1 MALT1 CELF2 FOS TAGAP GABARAPL1 GNA13 MBNL1 IL18 BRWD1 CD1E DOCK10 CAMSAP2 HAT1 DISP1 SERPINE1 C5AR2 GJC1 TBC1D23 PLXDC2 FPR3 HMGN2	down	**
GO_CORNIFICATION	0.0050113	0.0428727	0.4070179	0.4742390	1.675844	39	PCSK6 LIPM KRT5 PKP2 PKP1 KRT16 KRT15 FLG TGM1 PERP KRT18 TMEM79 ST14 PKP3 PKP4 KRT19 KRT8 SPINK5 PRSS8	up	*
PID_AMB2_NEUTROPHILS_PATHWAY	0.0032712	0.0311822	0.4317077	-0.4450398	-1.674646	34	FYN FGR RHOA RAP1A JAM3 PLAUR ROCK1 NFKB1 SELP JAM2 HCK IL6	down	*
GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN	0.0003536	0.0056070	0.4984931	0.3690360	1.674530	176	TRIP13 FOXM1 KIF20A FAM81A MCM10 FBXW8 MND1 PBK BRCA1 TTK GINS1 CDK4 GTSE1 CENPA ECT2 CDC6 UHRF1 SMPDL3A CCNF DTL LIME1 COQ3 MANSC1 MELK PCDHGC4 KIF2C CPD MORN1 TRPT1 BRI3BP AHCY DSCC1 PERP PML FLNB SPRY1 NUSAP1 STON2 CENPH DNA2 TTC16 ABHD4 IFT52 ALDH7A1 NMRAL1 MNS1 C9orf152 ESCO2 GINS2 HIP1R CENPK DHRS1 CKAP5	up	**
GO_MYELOID_CELL_HOMEOSTASIS	0.0003595	0.0056866	0.4984931	-0.3328857	-1.673833	127	EPAS1 HMOX1 TAL1 KLF13 GATA2 HCAR2 TMOD3 TGFBR3 ANXA1 SH2B3 ADAM17 SLC7A11 GATA3 JAM3 RB1 SPI1 MPL AXL ID2 FCER1G LYAR INHBA ADD1 SRF NCKAP1L IL6 PKNOX1 ETS1 HSPA1B DNASE2 SP3 KLF2 FOXO3 EPB42 JMJD6	down	**
PUJANA_CHEK2_PCC_NETWORK	0.0000000	0.0000003	0.7614608	0.3318102	1.673758	675	TRIP13 FOXM1 BIK MYBPH RUVBL1 CDC45 FANCI TROAP CHEK2 BUB1B CCNB1 CENPF TIMELESS CPSF6 TTF2 NDC80 TTC39A BRCA1 BET1 TTK GINS1 CDK4 GTSE1 KIF14 GMPS POLE STIL PLK1 AURKB CENPA PTTG1 ESPL1 CDC6 TPX2 TFDP2 CCNB2 NBR2 RBBP8 MCM4 MCM2 TYMS XPNPEP1 MYBL2 CCNF SHMT2 NCAPD2 ZWINT CDT1 COX11 CCT2 LSM5 NME1 LDHB RANBP1 CASP2 MELK HMMR EXO1 NUDT1 SMARCC1 CHAF1A LAMC2 MKI67 KNTC1 PAFAH1B3 BUB1 EEF1E1 TOP2A IDO1 CCT5 AURKA CBX3 ATR KIF2C MCM7 CD2AP MPHOSPH9 RRM2 PRKDC WDHD1 RAD54L MRPL3 KIF11 MCM3 LMNB1 RNFT2 LIG1 POLR3C TOPBP1 CHEK1 DNAJC9 ACTL6A MAD2L1 FBL RAD51AP1 CAD ETFA BLM CNOT3 MNAT1 MYO1A PARP1 THOP1 CKS1B CDKN2C TMEM106C ANAPC5 CDK1 HDGF SSBP1 POLE2 SNX4 UCK2 CCT3 ATIC GTF2E1 RBCK1 NPM3 UNG TCF20 DNA2 SEC61G FEN1 EZH2 NUP205 SPAG5 NF1 TTI1 SNRPE NOP2 RECQL4 PA2G4 RNASEH2A POLR2H DNMT1 VBP1 PELP1 ILF2 TRIM24 CDC23 GNPAT DLGAP5 PSMA5 ADNP AGL SNRPA LMNB2 RAD9A PSME2 HIRA HMGN3 SSRP1 DPH2 DTYMK HDAC1 TP53TG1 ANP32E TCEA1 KIF20B TM9SF4 ELAC2 CDC7 ABCC10 PFAS CPSF4 KLHL23 CDC20 IARS2 PPP1R8 ACLY RPA1 POLR2J MCM6 TBCA MED24 PRMT1 UTP20 MCM5 LSM7 TFAP4 SRSF1 AATF RCC1 LSM4 PSMB4 TXNL4A CHRNA5 TSR1 TCERG1 NUP62 PMS2P1 MSH2 CCNA2 SMARCA4 ZNF195 SNRPD2 RFC5 WDR77 HK2 ARHGAP11A SRP9 PAXIP1 SNRNP200 UBAP2L ZNF131 SMC2 PARG CENPE TCF3 PFDN4 DDX52 POP4 SMPD4 NMT1 SEPHS1 PAICS CHERP SNRPC PPIA UBE2C PNN TAF4 GPN1 PWP1 RIMS1 NUP210 RAD1 SMARCB1 RRS1 ZNF337 SART3 ERCC3 GEMIN2 PARP2 LYPLA1	up	***
chr19q13	0.0000000	0.0000008	0.7477397	0.3341296	1.673603	594	RHPN2 CEACAM1 KLC3 FOXA3 CEP89 GRIN2D FBXO27 PDCD2L NPAS1 TMEM86B PTPRH WDR88 GPATCH1 LHB BRSK1 ZNF285 CNTD2 GPI ZNF221 SPINT2 LSR ARHGAP33 ZNF888 PHLDB3 SLC7A9 ZNF283 COX6B2 LIPE-AS1 LILRB4 EPS8L1 SIPA1L3 HAUS5 WDR62 RUVBL2 ZNF607 C19orf48 DYRK1B KCNN4 ZNF850 CBLC LINC00665 PAFAH1B3 MYBPC2 ZNF112 ZNF587B NCCRP1 PSENEN ZNF766 SYNE4 SAE1 IRF3 LIPE PDCD5 CCDC114 ZNF146 ZNF226 ZNF530 CAPN12 LIG1 SARS2 CGB7 FBL CLIP3 XRCC1 PIH1D1 DNAAF3 TIMM50 AKT2 GEMIN7 ZNF507 RNU6-611P PPP5C SYMPK FUT2 CNOT3 ZNF587 ERCC2 HSPBP1 SRRM5 PPP1R37 ZNF229 ISOC2 ZNF480 APLP1 SUPT5H DMKN ZNF45 CCDC61 CEACAM16 SIGLEC12 ZNF260 VN1R1 SPACA4 ZNF541 GIPR SMG9 ZNF419 MAP3K10 KCNJ14 RN7SL789P FAM98C ZNF584 MRPS12 THAP8 ETFB CXCL17 PSMC4 ZNF324B DHX34 ZNF606 CATSPERG C19orf18 GRAMD1A OVOL3 ZNF671 C19orf47 ZNF233 JOSD2 SNRPA LRFN3 ZNF468 ZNF234 ZNF544 ZNF417 KCNC3 CADM4 ZNF761 PINLYP ZNF816 MEGF8 LIN37 BCL2L12 POLD1 FXYD3 ZNF814 PRRG2 ZBTB45 ZNF416 MAMSTR EPN1 FAM71E1 ZNF841 STRN4 CA11 ZNF428 ZNF616 CLASRP ZNF497 PPP6R1 ZNF780B IGFL2 ZNF320 MYPOP ZNF160 ZNF223 CACNG8 ZNF446 CYP2S1 ZNF432 PRMT1 NOSIP TMEM147 KPTN ZNF749 ZNF599 EXOSC5 POLR2I SLC1A5 PRKD2 FFAR2 ZNF765 ZNF780A ZNF274 NTN5 EIF3K U2AF2 NUP62 ZNF580 CEACAM5 ZNF837 AP2S1 TPM3P9 ZNF571-AS1 ZNF224 CYTH2 C19orf33 RBM42 RCN3 ECH1 SNRPD2 BLVRB PAK4 CTU1 ZNF404 CCDC9 PRPF31 HAS1 ZFP14 PPFIA3 MARK4 ZNF71 SAMD4B ZSCAN22 SNRNP70 CHMP2A ZNF573 FAM83E TBCB ZNF610 ETHE1 ALKBH6 CLEC11A ZNF567 PNKP CPT1C EIF5AP3 ZNF793	up	***
CAIRO_HEPATOBLASTOMA_CLASSES_DN	0.0000934	0.0018212	0.5384341	-0.3150618	-1.673580	179	LIMS2 RAMP3 WFDC1 CAT LPXN HSD17B6 PTPRB ENG SLC10A1 EMCN GFOD1 KANK3 LDB2 AQP9 ALAS1 GAS6 DNASE1L3 PDE2A MMRN2 ABHD6 SPTBN1 KANK2 ZEB1 ATP10A SNED1 SYNPO ZCCHC24 TJP1 MYRIP ITIH5 NR1D2 SMAD7 ADIPOR2 ARL6IP5 FRY KLRB1 IL2RB FAM189A2 RCAN1 SNRK RRAS HIVEP2 PEA15 TSC22D1 AOX1 CD81 GABARAPL1 LMOD1 PAMR1 CDC42EP3 GIMAP5 ALDH2 DAPK1 GLUL NFKBIA KLRK1 GPR171 MAN1C1 PHYH EGR1 GHR DKK3 CX3CR1 PRKCH	down	**
HALLMARK_KRAS_SIGNALING_UP	0.0000519	0.0011156	0.5573322	-0.3178335	-1.673553	170	RBP4 SLPI EREG TMEM100 ACE PECAM1 USP12 IL1B PRKG2 BMP2 ENG MTMR10 FUCA1 CBL EPB41L3 TRIB1 ABCB1 APOD SEMA3B HBEGF ADAM17 MALL LCP1 RBM4 SPRY2 CD37 CDADC1 KLF4 PLAUR PEG3 LY96 LAPTM5 ID2 CCND2 FCER1G CCSER2 INHBA IL7R	down	**
REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES	0.0026021	0.0261464	0.4317077	0.4114350	1.673535	74	CEP72 NEK2 CEP70 PLK1 DCTN2 HAUS5 CEP250 ODF2 SFI1 CDK1 CENPJ FGFR1OP MZT2A MZT2B CEP63 CEP192 TUBG1 NINL CKAP5 TUBG2 CDK5RAP2 HAUS6 HAUS4 CEP152 ALMS1 TUBGCP4 CEP164 NME7 CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT CDK11B TUBGCP2	up	*
GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP	0.0001596	0.0028382	0.5188481	-0.3179257	-1.672857	168	ATXN3 INPP5K S1PR1 IL23A SDE2 BTG2 MED19 PAG1 CRK CSRNP1 MTMR6 PSTK DENND6A COQ10B LEPROTL1 TADA2B UBE2B WDR48 SLC25A32 IL7R UBASH3B MYLIP CCNY CREM DCTN6 PLK3 IFNGR1 MTMR9 FYTTD1 CCR7 CD83 ENTPD4 CEBPZ ZNF350 PELI1 SRSF6 ADPRM SMCR8 SH3RF3 CDC37L1 TSPAN14 MAP3K2 RELL1 KTI12 GEM INO80 NBN USPL1 UBE2D1 NUP98 RNF38 EPB41L4A MTUS1 ZNF791 PUS3 RBMXL1 CDC14A TNFSF8 RB1CC1 YRDC CSNK1G3 CD69 NOL9 SLU7 RAB11FIP2 NR4A3 HIVEP1	down	**
GO_DNA_METABOLIC_PROCESS	0.0000000	0.0000001	0.7881868	0.3301826	1.672856	736	HMGA2 TRIP13 DDX11 FOXM1 HELLS EYA1 RUVBL1 CDC45 TICRR PARPBP MCM10 FANCI CHEK2 NEK2 EYA2 CENPF TIMELESS POLQ UBE2T PAGR1 STOX1 MND1 PRIM2 PIF1 BRCA1 GINS1 SMPD3 NPAS2 DNMT3B PMS2P5 POLE NABP2 AURKB PTTG1 WDR70 CDC6 FIGNL1 RBBP8 UHRF1 MCM4 MCM2 RAD54B TYMS PMS2 XRCC2 ORC1 DTL CIB1 TDRKH CCT6A MCM8 LIG3 MIS18A GINS4 SMUG1 CDT1 CCT2 MAGEF1 NME1 TOP3B RUVBL2 EXO1 NUDT1 CHAF1A TP53BP1 POLM RHNO1 FANCA AUNIP TOP2A CCT5 GPER1 EME1 REC8 POLA2 ATR POLD2 SMARCAL1 MCM7 ASCC2 CLSPN MMS22L CDCA5 PRKDC TRRAP WDHD1 HELB RAD54L FANCD2 MCM3 CHAF1B EGFR LIG1 EME2 TOPBP1 CHEK1 ORC6 ACTL6A RAD51AP1 DCTPP1 XRCC1 THAP10 PRMT6 DSCC1 BRIP1 RAD18 BLM GRHL2 PPP5C PHB PML ERCC2 MNAT1 RECQL5 PARP1 POLN TERC CDK1 POLE2 RFWD3 PICK1 CCT3 EEPD1 UNG DNA2 AP5Z1 NEIL3 FEN1 EZH2 MAD2L2 RECQL4 TEP1 RNASEH2A KPNB1 POLR2H DNMT1 FANCG TELO2 CCNE1 DCLRE1C SMG5 FANCF POLL MBD4 RAD9A MC1R LONP1 KIF22 RAD51D SSRP1 COPS7B FBXO4 TK1 CHTF18 ESCO2 MGMT GINS2 FZR1 NUDT16 TCEA1 USP43 LRWD1 PRMT7 KRBA2 POLD1 POLB ATAD5 PARP9 COPS6 SLX4 CCT7 CDC7 DNASE1 RAD50 ANKRD31 BAZ2A KLHDC3 SH2B1 UBQLN4 SUPT16H PGBD5 PALB2 YLPM1 TWIST1 HMGA1 ASCC1 ALKBH4 RPA1 POLR2J FANCM UBE2V2 MCM6 MGME1 DNMT3A CHTF8 WRNIP1 XRCC4 MCM5 NMNAT1 ANKRD1 TDP1 ZRANB3 UIMC1 GINS3 EXOSC5 POLR2I IGHMBP2 PRKD2 PRMT5 PMS2P1 MSH4 PMS1 MCRS1 APOBEC2 MSH2 PRIM1 ZNF93 NFRKB DTX3L BANF1 RTEL1 RFC5 STAT6 CEP164 INO80E RAD51 N6AMT1 TNKS1BP1 ST20 EYA4 PAXIP1 NUDT16L1 SIRT6 PNKP TONSL PARG BCL6 XPC ZNF91 TCF3 MPG SWI5 TP53 NEIL1 APEX1 PPIA RAD1 SMARCB1 ATF7IP DDB2 NAT10 PIAS4 HGF TK2 HEMK1 ACTR5 TMEM161A ERCC3 ALKBH2 PARP2 TTC5 APOBEC3B INO80B MUS81 DNASE1L2 SPIDR MLH3 TOP3A METTL4 C11orf80 GSK3A DFFB PRPF19 HDAC10 MYO18A HUWE1 ATRIP EXOSC10 CDC34 NHP2 RAG1 NPM1 RNF8 BATF PIWIL4 PARP4 DCLRE1B TEFM MSH6 MTRR DCLRE1A ASCC3 EHMT1 POT1 ZSWIM7 HERC2 RMI1 LOX XRCC5 ETAA1 TIPIN	up	***
GO_ENDOTHELIAL_CELL_PROLIFERATION	0.0001757	0.0030735	0.5188481	-0.3310079	-1.672440	125	ACVRL1 HMOX1 TEK PPARG GATA2 BMPER BMP2 CAV1 CDH13 BMPR2 MIR27B MIR146A PTPRM ADAM17 CAV2 NR4A1 RGCC AKT3 IL10 STAT5A NRARP TNFSF12 THBS1 MIR24-2	down	**
GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_UP	0.0001089	0.0020770	0.5384341	-0.3179444	-1.672316	164	GPR65 MIR22HG SIK1 LDB2 CITED2 YPEL5 TXNIP ANXA1 DPEP2 BTG2 CLK1 TCF7L2 ITPRIP PSTK KLF4 COQ10B LEPROTL1 DUSP1 IL7R MYH11 PIK3R5 MAFF MYLIP WASF2 KLRB1 SGK1 HCST MAP4K4 TYROBP JUNB SKIL FOS KLF2 YPEL2 ZNF669 BIN2 ADPRM VAV3 TGIF1 FAM228B ZNF844 IRS2 KCNA3 TOB1 RGS2 PDE4B EPHA4 OSER1 RORA ITCH ZFAND2A TNFRSF10D ARRDC2 CDC14A TNFSF8 MDS2 NR4A2 CLEC4E GPR153 FAM8A1 SLC26A11 ASH1L-AS1 MICAL1	down	**
GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN	0.0001390	0.0025322	0.5188481	-0.3207765	-1.672299	156	SLC6A4 SOWAHC TUBB1 IL1RN TOE1 RBM7 ANXA1 MAN2B1 LATS2 CHMP1B EIF4E JAM3 CD93 HNRNPU MCL1 EIF1B CDADC1 ID3 THBS1 ADAMTS9 CXCL2 ATF3 ELAC1 SELP HOPX UBE2B CLEC9A VWF PROCR SLC25A25 PDE5A GPR141 FERMT2 SKIL MBNL2 HOMER1 CXCL5 RNF24 KLRC2 CCR4 SMCR8 TOB1 ARPP19 RTN4 NLRP3 KLRK1 PAIP2 EIF4G2 CBX7 JDP2 GNG11 PTDSS1 SPTY2D1 ABHD14A AKAP12 DR1 NR4A3 CFLAR NFKBIZ SKP1 KLRC1 FBXO33 RFC1 TNFAIP6 PLCL1 TRPC6 ADAMTS1 EEF1A1 WDR75 SNX20 RBPMS2 WDFY1 ALOX12	down	**
MODULE_19	0.0000024	0.0000809	0.6272567	-0.3018609	-1.671550	262	EPAS1 SC5D CD55 FABP4 CLEC3B PHYHIP ENG LPL CITED2 ALAS1 TGFBR3 PDE4C FUCA1 EPB41L3 TGFBR2 HSPG2 ABCB1 TMX4 PDE2A APOD PTS CYB5A ACOT2 RNASE1 NR4A1 NFE2L2 SPTBN1 APOC1 KRT4 RHOB PTPN12 MAP2K3 CFD SCP2 BIRC2 EPOR AOC3 PEG3 DAB2 GMPR CADM1 CCND2 PER1 ADIPOR2 MYH11 MAPRE2 PTH1R EMP3 SGK1 LAMB2 RAB31 ST6GALNAC4 PLK3 JUNB PPP1R15A COBLL1 FSTL3 TNFRSF10B CLN3 WDR7 CD34 PLCG2 FOS PTP4A1 MSMO1 FOSB LRRC32 AOX1 COL15A1 FCGRT RGS2 MBNL1 PCCA SOD3 GPX3 CXCR4 CDKN1C ALDH6A1 GPD1L TIMP3 MTUS1 LDLR GRB10 IQGAP1	down	***
DANG_REGULATED_BY_MYC_DN	0.0000173	0.0004466	0.5756103	-0.3061735	-1.671463	211	ACP5 HMOX1 TMEM126A BDNF CAV1 LAMP1 SLC11A1 TGFBR2 JPH2 MAN2B1 HBEGF GM2A HSPB1 RB1 SDCBP CASP1 LIMS1 KLF4 PLAUR ITM2B RRM2B ID3 ROCK1 GAA THBS1 CEBPA KLF7 MYO1B CDKN1A CTBS ID2 DUSP1 INHBA WFS1 FOXN3 MYO1C VAMP3 MAGI2 CD48 PPP1R15A SP3 DDX5 DLEU2 ACSL1 CD151 HIVEP2 MYL12A TIMP2 TGFB1 PEA15 SERPINB1 PIM1 CSDE1 FCGRT SERINC3 TSPO CCNH SCPEP1 ISCU EDN1 PAK2 RAB2A PMAIP1 LYZ HNRNPH1 UBE2V1 CHP1 SERPINE1 CDKN1B DUSP6 ITGAL ITGB1 FTL	down	***
GO_REGULATION_OF_CELL_ADHESION	0.0000000	0.0000003	0.7614608	-0.2757288	-1.671417	579	TNR SIRPB1 LIMS2 DAB1 AJAP1 SEMA6A ACVRL1 FOXF1 SWAP70 TEK DLC1 CCM2L ADTRP CD55 SPN IL1B ATXN3 WNT4 LPXN EMP2 RDX BMP2 FYN CD44 BAG4 CAV1 CORO1C MYADM CITED2 CDH13 S1PR1 PRKAR1A CDC42 MIR27B NEDD9 CD9 IL1RN TGFBR2 IL23A RHOA APOD CD36 ANXA1 MIR146A SH2B3 CD5 ADA FOXA2 PLXNA2 ITGA5 MAP3K8 FZD4 HLX PAG1 GATA3 PPP3CA JAM3 SIRPA PLXNA4 RGCC TRAF6 CRK SFRP1 WNT3A TFRC FOXC2 NODAL ZMIZ1 IL10 ROCK2 NRARP DUSP3 NPNT PTPRO DENND6A LIMS1 BST1 PTAFR KLF4 ROCK1 THBS1 STX3 CLECL1 SOCS5 FAM49B PDE3B PTPRC JAM2 IGFBP2 SFTPD DUSP1 SMAD7 PEAK1 IL7R UBASH3B HES1 ARHGDIB TGFB2 GNRH1 SRF NCKAP1L NINJ1 KANK1 FAM107A CD80 PPP2CA IL6 CD160 UTRN NDNF NOTCH1 ETS1 PDE5A RAC2 MAP4K4 PODXL CCR7 PIK3R1 CD83 PRKCE GRB2 MALT1 RC3H1 HSD17B12 DOCK8 AP3B1 FSTL3 TBX21 TIGIT PPM1F PELI1 CD164 MBP RUNX3 CD74 EPHA3 TGFB1 VAV3 CD1D ZBTB1 CD6 YTHDF2 LRRC32 MIA3 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1 CLASP2 MACF1 SPOCK2 ADAM10 ABI3BP UNC13D ICAM1 IL18 ABL2 ARPC2 EPB41L5 CXCR4 DACT2 RIPK2 NLRP3 HAVCR2 EPHA2 RND1 LIMCH1 RET ADORA2A PAK2 KLRK1 PTEN PRKG1 CYTH1 TNFSF9	down	***
OCT1_03	0.0002076	0.0035367	0.5188481	-0.3197837	-1.671339	162	DAB1 MS4A7 DLC1 PPARG BDNF TMOD3 CITED2 DYRK1A ANAPC15 NFIX MCTP1 ARSB LIFR PLXNA2 FAM89A SLC7A11 UBE2D3 GLDN MOAP1 RUNX1T1 ZNF423 ATL3 RIT1 ELK3 PTCHD4 MIR17HG PIAS1 FOXN3 PPP2CA NEK7 MITF LTBP2 JPH1 DDX17 RCAN1 FBXO11 SKIL CASZ1 NDST1 FOXO3 SRSF6 TCF4 AP1G1 MBNL1 AMD1 HNRNPK FNBP4 NFKBIA CHCHD7 PRKG1 PAIP2 NRP2 TLK1 CACNA2D3 ATP6V0A1 PLAG1 ZNF385B CX3CR1 FAM53B ZNF654	down	**
MIR200A_3P	0.0000003	0.0000132	0.6749629	-0.2921731	-1.671250	347	SEMA6A DLC1 OSBPL11 TRHDE P2RY1 SIK1 ZBTB34 TMEM170B EGR2 HCAR2 IBA57 PAFAH1B2 NR3C1 CBL ZEB2 ERG EDEM1 B3GNT5 FOXA2 C1orf21 HIPK3 KLF6 GLS SLAIN2 FOXJ3 PLXNA4 LHX6 TNS1 TMEM41B ZEB1 ZYG11B ARRB1 DUSP3 RNFT1 ZCCHC24 PEG3 MED6 VRK2 SOCS5 MYRIP SPAG9 NPAS3 KCTD20 CCND2 ELK3 PLEK ARL4A RSL24D1 KIAA0408 CYP26B1 NCKAP5 IKZF5 TGFB2 C2orf69 CREBRF HCAR3 RAB8B PIKFYVE TMTC1 SLC14A1 MN1 APBB2 CSTA PRKCE GRB2 CREB1 TSHZ3 TTBK2 TCF4 YTHDF2 IFNAR1 IRS2 MAP3K2 ATXN1 CLASP2 GNA13 LTBP1 KIF17 PHLPP2 MBNL1 MLANA INO80D MIER1 ABL2 FKBP1A ITPRIPL2 CDC42EP3 TIAM1 TTLL7 PTCH1 IPO5 EPHA2 DAPK1 LYSMD3 RASSF8 ARPC5 FNIP2 FAM126B C21orf91 DOCK4 GSG1 SFPQ WDFY3 SPOPL MIER3 HSDL1 ARHGEF18 SUGT1 PLAG1 CHP1 CDC14A GJC1 HMGCS1 SLC19A2 MYH10 DCUN1D3 RB1CC1 PIAS2 FAM160B1 UBE3A C11orf54 KIDINS220 GABPB1 ATP8A1 DR1 WWTR1 CNTN1 SLC23A2	down	***
GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN	0.0000559	0.0011825	0.5573322	-0.3173931	-1.671234	170	CXCL3 EREG KMO DENND5A ROBO4 RAPGEF2 BMP2 SLC39A8 CDC42EP2 OTUD4 LRRFIP2 ADA EIF1 BZW1 LITAF SLC7A11 RBM4 ARHGEF2 CASP5 MAP2K3 STAT5A SNAI1 PTGIR TJP1 SOCS2 SNIP1 CXCL2 TP53BP2 MARK3 AKIRIN1 NINJ1 CD80 SAR1A PSEN1 RAB8B PPP1R15A PTGER4 GRB2 REL PELI1 HIVEP2 PRKCG RIN2 EHD1 ITGA9 FPR2 PHF11 MFSD12 PDE4B GTF2B ARAP2 ABL2 NBN DCTN4 LRP12	down	**
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN	0.0000001	0.0000035	0.7049757	-0.2868080	-1.671091	413	DENND5A GLIPR2 ZC3H12C ENG BDNF HSD17B11 CD44 PPP4R1 CCDC88A BACH1 ST3GAL6 CAV1 CORO1C FOSL1 QKI NR3C1 TGFBR2 RFTN1 HEG1 ANXA1 EIF4A1 SH2B3 ASAP1 PTPRM B3GNT5 TTL EMILIN2 ECHDC1 ZDHHC2 PICALM ANXA5 LUZP1 RNF182 GLS PRSS12 CAV2 PTX3 NDEL1 SLC25A37 SFRP1 AKT3 SPTBN1 SPRY2 KANK2 ZEB1 SRGN PDGFA TUBB6 ZYG11B EPB41L2 FLI1 ITPRIP CCDC82 SGTB SDCBP CASP1 ZCCHC24 PRKD3 DAB2 BCHE GRK5 ABCC4 SPAG9 MARVELD1 CXCL2 IRAK2 VIM AXL LBH ARAP3 ELK3 INHBA DSE IL7R UBASH3B CYP26B1 PAFAH1B1 CRIM1 CNRIP1 ACTR2 TGFB2 EMP3 FMNL2 IL6 SGK1 SOCS3 MAML2 RAB8B PNMA2 RAB31 KCTD12 LTBP2 ETS1 HRH1 MSRB3 MAP4K4 CCDC50 ELP5 GLIPR1 PABPC4 MALT1 NOL7 GFPT2 MCAM AGPS NAP1L5 FLNC TIMP2 TGFB1 SERPINB1 MTMR2 TGFB1I1 CTNNAL1 GNAI1 NAB1 PIM1	down	***
GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP	0.0000533	0.0011385	0.5573322	-0.3142869	-1.671057	175	CD300LF ADTRP OSBPL1A HHEX GATA2 SPN TTC7B BAIAP2 CRY2 GPCPD1 SLC25A30 CD9 IL1RN MOB1B CD5 HIPK3 SIRPA HNRNPDL TFEC TMEM38B CCNI ROCK2 DGKE CASP1 BST1 USP2 GRK5 SOCS5 COTL1 PIK3C2A CPT1A CMTM6 MCMBP TECR RAB8B DDX47 DESI2 JAK1 IPO7 EEA1 NAA30 CD1D VAMP4 CSDE1 GNA13 ADAM10 PLA2G15 ATAD2B RBL2 CPQ INO80 RTN4 FNBP4 CTSC B3GNT2 IQGAP1 DUT MACROD2 BMI1 UBAP1 NAF1 PRKCH ITGB1 FTL	down	**
GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP	0.0001789	0.0031224	0.5188481	0.3686578	1.670603	175	SPATA24 CPLX2 CDC45 BUB1B TSFM DEPDC1 IRS1 TUBB2B TTK E2F8 CDCA8 IGLC7 ESPL1 KIAA0895 MELK EME1 KLHL25 KIF2C CENPW GPSM2 PPP1R35 ZNHIT1 CKAP2L CBY1 COX19 SPC24 GLE1 KNSTRN FAM221A TRIM2 NEIL3 SPAG5 STK11 LGR5 DLGAP5 TACC3 EFCAB2 AARSD1 ZMAT5 DUSP12 ARF5 ESCO2 PPME1 NAT9 CKAP5 CDC20 CENPM ZCCHC17 KLHL32 ZNF428 ASCC1 TDP1 DNAJC21 ENOX1 SMARCA4 ABCF2 WDR4 CARHSP1 F13A1 WLS RBM19 PNKP TRIB2 UBE2C MSRB1 ZFPM1 NCAPH CD38	up	**
GO_INTERFERON_GAMMA_PRODUCTION	0.0016304	0.0183393	0.4550599	-0.3509724	-1.670573	86	SPN IL1B IL1RL1 GAS6 SLC11A1 IL23A CLEC7A GATA3 SIRPA IL18R1 PDE4D IL10 FAM49B AXL TLR4 MIR24-2 INHBA CD160 CCR7 IRF8 AZI2 KLRC4-KLRK1 PDE4B IL18 IL18RAP RIPK2 HAVCR2 KLRK1	down	*
GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_UP	0.0001554	0.0027765	0.5188481	-0.3147147	-1.670453	180	CD300LF MS4A7 GLIPR2 ZC3H12C RAPGEF2 ST6GALNAC3 KIAA1109 GTF2I RFTN1 TMX4 DNASE1L3 EDEM1 CNST FAM89A PBX3 LITAF REV3L SIRPA RGCC TXN IL10 MPEG1 KLF4 PLAUR COQ10B STK17B TMED5 VRK2 MGAT4A PDE3B DUSP1 PLEK ARL4A RSRC2 LACC1 CD80 CHDH BCAR3 HIC1 MN1 HSPA1B JUNB DUSP8 FSD2 TPP2 DOCK8 TBX21 SLC3A2 PNPLA2 UBXN2A EHD1 GSAP TEX30 SBF2 CTNNAL1 CD86 IFNLR1 RNF138 HSPA2 HSPA8 FDX1 GPR171 SAMSN1 C21orf91 NRP2 EHD3 BMI1	down	**
GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT	0.0000000	0.0000000	0.8753251	-0.2685362	-1.670376	844	ANGPT4 SEMA6B SEMA3G SEMA6A EREG MGAT3 ACVRL1 SASH1 FOXF1 HMOX1 SWAP70 TEK CXCL16 GCSAML ACE PHACTR1 DLC1 SGK3 PECAM1 PPARG ADTRP ROBO4 GLIPR2 GATA2 SPN IL1B TIE1 WNT4 EMP2 RDX RAPGEF2 BMPER BMP2 CDH5 ENG BAG4 LDB2 CAV1 CORO1C MYADM CITED2 CDH13 BMPR2 TBXA2R C5AR1 S1PR1 FGF10 MIR27B TGFBR3 NEDD9 CD9 GAS6 LAMP1 TGFBR2 TRIB1 SCN5A IL23A FGR RHOA NUMB APOD SEMA6D ANXA1 MIR146A MMRN2 PLA2G7 PTPRM MCTP1 SEMA3B HBEGF ADA ARSB ADAM17 LMNA PLXNA2 CLEC7A ITGA5 HSPB1 ANXA5 FOXP1 ADIPOR1 ABHD6 DACH1 GATA3 PPP3CA JAM3 PLXNA4 RGCC NFE2L2 GRN CRK SFRP1 AKT3 SPRY2 WNT3A ARHGEF2 PDE4D PDGFA FOXC2 NODAL RHOB ADARB1 MAP2K3 ROCK2 STAT5A AMOTL1 SNAI1 DUSP3 TNNC1 SDCBP PTPRO BST1 ZSWIM6 TRIM46 TACR2 PTAFR KLF4 ROCK1 DAB2 THBS1 ADAMTS9 CLDN5 CLIC4 SPAG9 CCL3 SSH1 ITGAX PTPRC SELP CCL4 JAM2 MIR24-2 RECK XCL2 DUSP1 PIK3C2A SMAD7 TBX5 OXSR1 NUS1 GNAI2 RUFY3 IL24 ANXA3 AKIRIN1 MAPRE2 ARHGDIB TGFB2 STK24 GNRH1 SRF SRGAP2C NCKAP1L PRCP KANK1 MYO1C FAM107A SLC8A1 FLT1 IL6 SGK1 APPL1 PODN MAGI2 JUN MITF LRCH1 NOTCH1 RHOBTB2 ETS1 RAC2 MAP4K4 ELP5 DUOX1 RHOG RHOJ PTGER4 PODXL CCR7 DAPK2 PIK3R1 ACKR3 PRKCE GPR183 DOCK8 PPM1F MCAM PLCG2 CD151 RRAS PTP4A1 FOXO3 EPPK1 CD74 WNT11 TTBK2 TGFB1 OSGIN1 FPR2 MIR23A CYGB MIA3 IRS2 CD81 SOD2 LGALS3 KLRC4-KLRK1 MYOCD CCR1 CLASP2 GNA13 MACF1 GPR18 PLAA SPOCK2 ADAM10 PDE4B CCL20 HACE1 CCR6 ICAM1 LDLRAD4 FGF2 ABL2 VASH1 EPB41L5 SEMA4A RTN4 IQSEC1 TIAM1 CXCR4 ARHGAP18 SP100 EPHA2 RND1 GLUL LIMCH1 RET ABI3 KIT EDN1 DOCK10 SCAI KLRK1 PTEN MTUS1 PRKG1 FGFR1 NRP2 DOCK4 NRG1 RHOT1 IQGAP1	down	***
GO_REGULATION_OF_EPITHELIAL_CELL_APOPTOTIC_PROCESS	0.0040695	0.0366383	0.4070179	-0.3714894	-1.670284	64	HMOX1 TEK GATA2 SFRP4 RAMP2 ECSCR GAS6 GATA3 RGCC NFE2L2 TCF7L2 THBS1 MIR24-2 WFS1 IL6 CD160 NDNF SRSF6 SPOP SORT1 ICAM1 ARRB2 BOK ANO6 SERPINE1	down	*
GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN	0.0004986	0.0073344	0.4772708	0.3693652	1.669965	174	TRIP13 EGLN3 AK4 KNOP1 CA12 EIF3B ACY1 CASP2 MRPL15 EXOC4 SAE1 ASCC2 COASY TTLL12 GCAT PKM XXYLT1 DCTPP1 SLC39A11 SSBP1 L2HGDH DGAT2 NUP205 DDT DPP3 CDC23 GNPAT GPR68 MLF2 SPTSSA DUSP12 DNAJC11 NDUFA13 TRIM32 ASNS SAP30 C15orf41 TSEN54 SND1 SIL1 C12orf73 MAGOHB CENPV IARS2 ZNF428 METTL2B UTP20 TDP1 POLR2I GRHL1 HLCS GRAMD1B SUPT3H ACP1 CPOX UQCRQ XPC PFDN4 NDOR1 TRUB1 SIGMAR1 TAF4 FBXO45 NDUFAF6 ZNF511 ISYNA1 C7orf25 RPP25 HRAS PPARGC1B ZNF771 NHP2 CCDC6 GCSH NETO2 LRP8	up	**
GO_NEGATIVE_REGULATION_OF_INFLAMMATORY_RESPONSE	0.0004054	0.0062241	0.4984931	-0.3336415	-1.669917	114	FFAR4 GPR17 ACP5 FOXF1 TEK PPARG WFDC1 CDH5 CALCRL APOD MIR146A ADA GATA3 SIRPA RB1 GRN IL10 MEFV KLF4 SOCS5 NFKB1 NR1D2 PTPRC PTGIS SOCS3 PSMA1 ETS1 PTGER4 CST7 SMPDL3B FPR2 NLRP6	down	**
ROSS_AML_WITH_AML1_ETO_FUSION	0.0035237	0.0330829	0.4317077	-0.3763543	-1.669595	61	IL17RB WFDC1 CAV1 TBXA2R IER2 CACNA2D2 LCP1 CD58 PTPN12 PTGIR RUNX1T1 KLF11 LAPTM5 VAMP5 HPGDS PALM RPS6KA1 CD34 ADPRM	down	*
GSE13547_WT_VS_ZFX_KO_BCELL_UP	0.0002838	0.0046583	0.4984931	-0.3247451	-1.669531	147	SLPI ARHGAP31 SOSTDC1 CD101 ACE ENDOU SECISBP2L CD55 CPEB2 ST6GALNAC3 FYN PLEKHA1 YPEL5 NEDD9 DNASE1L3 ZEB2 LRRFIP2 ZBTB4 LATS2 AKT3 IL10 CCL4 LBH CCND2 SNN PIAS1 TBC1D5 CREBRF FRY NSMAF SNX29 JAK1 DAPK2 CD83 PTGER2 CD7 STRN BAZ2B TEC HNRNPH3 RGS2 SYT11 RNF2 RBL2	down	**
GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_UP	0.0001082	0.0020670	0.5384341	-0.3153872	-1.669195	169	AKAP5 MS4A7 LRRFIP1 TGFBR3 ZEB2 DNAJB14 ATP2B1 SIRPB2 LATS2 EIF1 C1orf21 ABCG2 ADRB2 IL18R1 ERP44 LAPTM5 P2RY2 CCL4 SNORA28 PRF1 FCER1G DSE SH2D2A ACTR2 CREBRF C20orf194 SHOC2 WTAP PTGER4 PSTPIP2 ZNF683 RUNX3 NKG7 SERPINB1 FAM228B DUSP5 SYT11 NEK1 ITPRIPL2 HAVCR2 S100A4 BCAT1 PDE4A PAK2 CREG1 PAPSS2 EGR1 DUSP6 SH3BGRL3 NR4A2 CLOCK KMT2E ATP1B1 C6orf62 FBXW12 ZBED6 TSC22D2 S1PR5 ATP2B4 KATNAL1 METRNL GZMB CYP1B1 GPATCH2L ZNF80 RANBP2 IL10RA ANKRD17 AP5B1 TRA2A DUSP10 BCAP29 HIP1 SESN2 WAC-AS1 SNTB2 RAP2A TLR3 PHF20 SMURF2	down	**
GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN	0.0005570	0.0080363	0.4772708	0.3704247	1.668831	165	DDIT4 SORD STIL SPINT2 CCNF SHMT2 GSDMB MAGEF1 PAQR4 STAP2 COPG2 AURKA NDUFS2 MPHOSPH9 SLC9A3R1 CBX5 ASF1B CD300A DTD1 POLR3K KIF2A FEN1 CBX1 RECQL4 FOCAD CHCHD3 SNRNP25 DNMT1 RHOC GNPAT GALK2 GSS SLC37A4 MTA3 PRMT7 GFM2 COPS6 NADSYN1 P4HA1 ANKRD6 FBXO22 SIRT5 TMUB1 CCNA2 SNRPD2 ARHGAP11A MICU1 WDR76 TMEM101 ETHE1 VDAC3 PAICS PCBD1 SPATA20 DDB2 C4orf46 LINC00888 PRKAG1 CLNS1A TFB1M CD38 APEH EIF2D ZDHHC13 CLPP SRI MCEE MPST RNF144A	up	**
GO_REGULATION_OF_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	0.0026895	0.0267417	0.4317077	-0.3676769	-1.668787	69	HMOX1 SCIMP IL1B CD36 GATA3 IL18R1 TRAF6 IL10 TLR4 FCER1G SMAD7 TGFB2 IL6 CD160 MALT1 TBX21 CD74 TGFB1 CD81 IL18 NLRP3	down	*
GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP	0.0000895	0.0017609	0.5384341	-0.3196738	-1.668748	158	RAB11FIP1 HHEX RCOR1 FOLR1 RTN3 MTMR10 YPEL5 AGTPBP1 TGFBR2 FAM49A TMX4 CHMP1B NDEL1 SLC25A37 TLE4 AOC3 ST3GAL2 OSTF1 COTL1 PTPRC ARAP3 PPP2R5C GNAI2 NRBF2 PRCP RYBP NEK7 GLIPR1 DOCK8 TAGLN2 CELF2 TIMP2 ZRANB1 BAZ2B IRS2 MAP3K2 HBP1 APLP2 ACTN2 PHF2 BNIP3L XKR8 TOB2 TBC1D1 METTL7A KIT ARPC5 PTEN FAM126B CYTH1 PAIP2 IQGAP1 SPOPL HIPK1 CX3CR1 MAPK1 RAB37 NFAM1 FAR1 FAM160B1 STX16 MAP3K1 TRIM25 WDFY2	down	**
GO_REGULATION_OF_NUCLEAR_DIVISION	0.0005856	0.0083772	0.4772708	0.3707196	1.668305	162	TRIP13 BUB1B NEK2 CCNB1 CENPF NDC80 TTK SMPD3 L3MBTL1 ANLN PLK1 AURKB PTTG1 ESPL1 CDC6 CDT1 SPDL1 RANBP1 MKI67 CUL9 CUL7 FBXO43 KNTC1 BUB1 MSX2 AURKA TPR MAD1L1 MSX1 CDCA5 TOM1L1 KIF11 HORMAD1 CDC25C CHEK1 MAD2L1 PKMYT1 NUSAP1 ANAPC5 CEP97 EGF MTBP MAD2L2 KLHL22 CDC23 DLGAP5 TACC3 FZR1 KIF20B ANAPC1 CDK13 SH2B1 CDC20 CHMP4C CDK5RAP2 RCC1 PRMT5 NUP62 CEP85 CHMP1A CHMP2A AURKAIP1 LIF CENPE UBE2C MAP9 RAD1	up	**
GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP	0.0001363	0.0024934	0.5188481	-0.3147225	-1.668200	181	HCAR2 CCRL2 SLC39A8 STX11 VAPA TET2 IER2 PPP1R15B HDC KLF6 TFEC CSRNP1 STAT5A PLAUR SLC12A4 ZFAND5 CLIC4 TMBIM1 MGAT4A P2RY2 MYH11 SPRYD7 KPNA3 AFF1 RSRC2 KREMEN1 SNN FLT1 RYBP APPL1 ETV3 LRCH1 RCAN1 DHX15 ACKR3 CD83 HSPA13 LGI4 RBM22 REL HNRNPA2B1 PIM1 GNA13 MICU3 PDE4B FAM98B GTF2B MOB3B INO80 ADAMTS4 RIPK2 IPO5 RND1 EDN1 TTC19 SFPQ TRIM36 SPATA13 SPHK1 YTHDC1 JDP2 RBMXL1 DCUN1D3 ZFP36 WAC FANCC DR1 NFIL3 PPFIBP1 FCHSD2 JARID2	down	**
WNT_UP.V1_UP	0.0006907	0.0095309	0.4772708	0.3789704	1.667796	133	CPS1 ENTPD2 HS3ST1 GRIN2D GALNT6 EYA2 UGT8 TFF3 STK36 LCN2 CHRNA7 AURKB DPYSL4 INSRR AP1G2 POLD2 IL12B KDELR2 THYN1 MST1R FNTB LTB4R HPS4 NF1 MYO5B FOXK1 ADAM28 RAD9A MC1R TSPO2 KCNC3 FXYD3 THRB DNAJB13 STRN4 CXCL1 CKMT2 CYP2S1 LANCL2 HTRA3 CKAP4 AP2S1	up	**
CHICAS_RB1_TARGETS_LOW_SERUM	0.0042405	0.0378744	0.4070179	0.4097110	1.667705	76	HELLS DEPDC1 CDCA7 MCM4 TYMS DTL CDT1 CENPW MCM3 LMNB1 SOX4 EGFR UQCR11 CKLF SNRPE UQCC2 ZNF827 RNASEH2A RAD51D COX7C SYT1 PTN MCM6 MCM5 ROMO1 LSM7 ATOX1 COX5B WDR76 SYNE2 NNMT COX6B1 ZNF367 TOMM7 C4orf48 OST4	up	*
GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0006726	0.0093667	0.4772708	0.3741820	1.667536	146	TICRR IGF2BP3 KIF18B FOXD4 TTK PLK1 FIGNL1 KNOP1 UMPS MCM8 NCAPD2 PUS7 AURKA IL12B WDHD1 FANCD2 ORC6 CBY1 SPC24 PPP5C CNPY2 TXLNB CENPH PSAT1 KSR2 LIPT2 KPNB1 EIF6 EFTUD2 MZT2B NPHP1 PSMA5 PUS1 MLF2 MRPL52 IQCG HMGN3 FAM207A TIMM13 WDR34 GPATCH4 THOC5 UTP20 TMEM147 CLUH SRSF1 LSM4 PRMT5 GRHL1 UQCRC1 SEC13 OXCT1 ZMYND19 TARBP1 PGAM1 TARBP2 MTHFD1 NMT1 TBL3 TMEM42 FTSJ3 TMEM161A BCKDK EIF2B1 ZC3HC1 LCMT1 PSME1	up	**
RAMASWAMY_METASTASIS_UP	0.0032080	0.0307169	0.4317077	0.4286326	1.667178	59	STIL PTTG1 GPI CAND1 MSX2 LMNB1 MAD2L1 URI1 BIRC5 RALGPS1 COL1A1 COL1A2 UBAC1 TRIM37 PRMT1 TMEM147 EIF3K NUP62 RBM42 GPN1 COX6B1 PCNT TMPO NHP2 HNRNPAB DHPS ITPA NSUN5P1 PSEN2 HOXA2 UPF2 ZFC3H1 TDG VPS13B CANX P4HB CHD2 UBN1 RAB5C FAM98A SRGAP2 NOTCH3	up	*
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN	0.0000006	0.0000254	0.6594444	-0.2897284	-1.667148	360	EPAS1 SIDT2 SWAP70 ABHD5 TSPAN4 PDLIM2 CAT ENG BDNF TMOD3 CAV1 GAS6 LAMP1 EOGT TGFBR2 RFTN1 SCARA3 RHOA AVPI1 ANXA1 BMP1 RRAGC ASAP1 ITGA5 ANXA5 KLF6 CAV2 PTX3 NDEL1 GRN CST3 ATP10A MTMR6 SCP2 PLAUR PXDC1 COQ10B ID3 DAB2 DRAM1 THBS1 TMED5 TPP1 MYO1B CLIC4 SPAG9 SSH1 PAPSS1 AXL LBH PLEKHB2 DUSP1 ELK3 SMAD7 INHBA SLC25A32 GNAI2 BACE1 CMTM6 ACTR2 HEXB TMEM9B VAMP3 NSMAF SNAP23 VAT1 RAB31 OSTM1 JAK1 GSTO1 SNX2 STX7 GLIPR1 HSPA13 IDS CAP1 FSTL3 TAGLN2 NDST1 CD151 GRSF1 ATP6V0D1 RRAS KLF2 ATG3 PKD2 XYLT1 TIMP2 TGFB1 EHD1 PEA15 TGFB1I1 CD81 APLP2 NQO2 GABARAPL1 STX12 NPTN ADAM10 TSPO MBNL1 PITPNA FGF2 PDLIM5 WDR1 ELOVL1 SEC61B SCPEP1 TMEM184B PARVA ARPC5 PTEN NRG1 IQGAP1 PSMD9 CNN2 FEZ1 PAPSS2 SPHK1 TMEM50A CLIP1 SH3BGRL3 TMEM43 CAPZB ENDOD1	down	***
GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_DN	0.0002231	0.0037712	0.5188481	0.3693881	1.667134	166	SPATA24 CPLX2 CENPF APOLD1 CLGN BRCA1 GINS1 SLC27A2 COLQ DGCR8 UHRF1 UMPS MYBL2 LSM5 KIF23 CEP55 AUNIP EME1 CDCA5 SBK1 FANCD2 ANG SMYD5 CKAP2L SPC24 INCENP THOP1 C1orf112 POLR3K TRIM2 TTC16 CBX1 RECQL4 CENPP RAPGEF5 NMNAT2 MYO19 LGR5 GOLGA3 DLGAP5 ATP6V0E2 TACC3 CENPQ GAS2 SAP30 CHADL CEP128 ZNF428 SNRPD1 HAUS6 MYEF2 STRBP ADM PRR11 WDR4 BRMS1 RNF7 POP4 NMT1 TBL3 E2F7 DDX41 SLC1A7 DLEU7 LONRF2	up	**
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_DN	0.0000001	0.0000068	0.6901325	-0.2858359	-1.666951	388	CXCL3 SLPI EREG IL1A ZC3H12C MIR22HG HSD17B11 CD44 PPP4R1 CCDC88A GFOD1 ST3GAL6 CAV1 CORO1C FOSL1 CYB5R3 NR3C1 TGFBR2 RBM7 ANXA1 BMP1 PTPRM B3GNT5 ADA CHMP1B GM2A ZDHHC2 LUZP1 PRSS12 CAV2 CAMTA1 SIRPA RGCC ADRB2 NFE2L2 NDEL1 SLC25A37 CRK SFRP1 AKT3 SPTBN1 SPRY2 SOX7 BTG3 TUBB6 CD58 CYBRD1 TLE4 CCDC82 CASP1 YBX3 PXDC1 PRKD3 TMED5 MYO1B CLIC4 COTL1 RBMS1 CXCL2 AXL LBH ARAP3 ELK3 INHBA DSE CLIP4 IL7R UBASH3B ANXA3 EMP3 ETF1 FMNL2 VAMP3 YBX1 SGK1 MAML2 STAT4 ETS1 HRH1 RAC2 OSBPL9 MAP4K4 DUOX1 IFNGR1 GLIPR1 MBNL2 NUDT15 OGFRL1 RALB AGPS MBP RUNX3 MYL12A MME MTMR2 GNAI1 NAB1 IRS2 RGS2 CSNK2A2 ETS2 MBNL1 GTF2B AMD1 ICAM1 FGF2 IL18 TNFAIP8 ARPC2 FKBP1A WDR1 CDC42EP3 CEBPD ORMDL1 TBC1D1 SP100 EPHA2 SCPEP1 SOAT1 RBMS3 COPS8 CTSC FDFT1 KIF1B NABP1 MT2A TOX2 TNFRSF10D CFL2 ZBTB16 TBPL1 TMEM30A SVIL GJC1 ITGB1 CMPK1 SH3GLB1 HP1BP3 CD109	down	***
HALLMARK_COMPLEMENT	0.0001804	0.0031416	0.5188481	-0.3167738	-1.666797	168	FCN1 OLR1 CD55 LTA4H LIPA PCSK9 FYN CDH13 CASP9 CD36 TMPRSS6 PLA2G7 SH2B3 CSRP1 GNGT2 ANXA5 GATA3 ZEB1 APOC1 CASP5 CASP1 PLAUR CTSD DOCK9 FCER1G PLEK GCA PIK3R5 GNAI2 C4BPB MAFF USP16 PRCP IL6 CTSS PSEN1 C1QA RHOG GRB2 CALM1 DGKG CR1 PPP2CB TIMP2 EHD1 DUSP5 MMP15 PIM1 GNB4 LGALS3 KYNU ACTN2 SPOCK2 CPQ FDX1 CTSC DOCK10 DOCK4 ZFPM2 HPCAL4 IRF2 SERPINE1 CTSH DUSP6	down	**
GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP	0.0001544	0.0027651	0.5188481	-0.3206705	-1.666706	155	CXCL3 PPARG ZC3H12C FABP4 LPL EGR2 SAMHD1 ZCCHC2 ELF2 ALAS1 CD9 IL1RN CD36 LMNA ENTPD1 CLEC7A CYB5A TNIP3 RNF144B ANXA5 ANPEP TTYH2 TFRC AHNAK MED11 CLIC4 ATF3 HPSE ATP6V0D2 GPR157 SPRYD7 CD300LB VWF VAT1 CPEB4 CCDC50 CD83 FOS CD74 LGALS3 GABARAPL1 BRI3 MFSD12	down	**
GSE12366_NAIVE_VS_MEMORY_BCELL_UP	0.0001094	0.0020832	0.5384341	-0.3227257	-1.666533	152	LIMS2 PTPRE FIG4 LYL1 MYADM SLC39A8 PLEKHA1 S1PR1 NFATC3 RFTN1 ABCB1 DNASE1L3 SWT1 FOXP1 PCDH12 LAIR1 MAPK8IP1 HIF3A YBX3 TM6SF1 GCA PEAK1 AFF1 IL6 DDHD1 ADAMTSL2 FOXP1-IT1 GAS2L1 ARHGEF10 CD83 PRKCE RC3H1 OGFRL1 XYLT1 HSF5 ADPRM CHPT1 GNB4 APLP2 CRY1 MEGF6 XIRP1 PSME4 FNBP4 CEPT1 EDN1 FDFT1 MMD P2RX1 MROH6 EHD4 FCRL1 ATP6V0A1 DUSP6 KBTBD11 PLEKHA2 FAM53B GNG11 CD79B PDE7B	down	**
HALLMARK_ALLOGRAFT_REJECTION	0.0001549	0.0027704	0.5188481	-0.3196450	-1.666400	156	EREG IL1B GPR65 LY86 IGSF6 CD8A FGR CRTAM SRGN SPI1 IL10 CCL22 SOCS5 PTPRC CCL4 CCND2 PRF1 INHBA KLRD1 HLA-DQA1 DEGS1 TGFB2 CD8B CD80 IL6 CTSS IL2RB STAT4 ETS1 IFNGR1 RPL9 IRF8 CD7 PRKCG CD74 TGFB1 CD1D APBB1 CD86 CCR1 ICAM1 IL18 IL18RAP RIPK2 NLRP3 UBE2D1 BCAT1 CD3G CCND3 IL16 ABI1 ITGAL UBE2N BCL10 CD3E TRAT1 IRF4 CD4 GZMB EIF3J CAPG CDKN2A ABCE1 CD47 FASLG GZMA B2M ITK HCLS1 CD3D CCR5 GALNT1 IFNG JAK2 TLR3	down	**
MODULE_17	0.0000078	0.0002259	0.5933255	0.3473953	1.666044	314	TRIP13 DDX11 CDC45 PRSS2 CCNB1 IGF2BP3 PSPH DDIT4 SORD TTK KIF14 GMPS NDUFS6 PLK1 AURKB PTTG1 AKR1C1 TPX2 CCNB2 MCM2 TYMS ORC1 CCT6A SRPK1 SHMT2 ZWINT HMMR NUDT1 CHAF1A GFPT1 EEF1E1 TOP2A CBX3 NDUFS2 POLD2 SNCG KIF2C MCM7 PRKDC MRPL3 MCM3 AIMP2 MDK CD24 CDC42EP1 AHCY PSMD4 PKMYT1 CAD PES1 TMED3 KRT18 CDK1 SSBP1 UCK2 ATIC RBCK1 FEN1 EZH2 NUP205 MRPS12 PSMC4 ITPR3 RNASEH2A RANGAP1 DNMT1 VBP1 LMNB2 MBD4 DPH2 TK1 DTYMK DAP3 ASNS SLC4A2 KRT19 LTBR CHPF P4HA1 KLHDC3 CKAP5 CDC20 IARS2 AHCYL1 RRP9 BCL2L1 MCM6 LSM7 TFAP4 RCC1 CCNG1 SLC1A5 SF3A2 ALG8 PYCR1 MSH2 CCNA2 SMARCA4 RBM42 PRIM1 BLVRB BMS1 SEC13 HOXB2 TRIB2 MTHFD1 DHRS3 PAICS APEX1 MRPS27 SNRPC NNMT PPP2R5D NUP93 CALU TRPC4AP TRAPPC6A CYB5B APOBEC3B MLLT11 POLRMT INPPL1 ITGB5 MRPL12 PRPF19 TMEM259 LPCAT1 CLPP APRT	up	***
REACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC	0.0000915	0.0017966	0.5384341	0.3647176	1.666033	185	KIF1A KIF12 KLC3 KIF20A KIF18B TUBB2B RACGAP1 RAB36 DYNC1I1 COPB2 KIF27 DCTN2 KIF23 BICD1 KIF15 COPG2 COPG1 PAFAH1B3 KIF3B YKT6 KIF2C RHOBTB3 KIF11 KDELR2 KIF3C TMED3 NSF KIF5A STX18 KIF19 KIF2A DYNLL2 RAB6B GOLGA5 ARFRP1 TUBB2A TUBA3D COG2 COG7 KIF22 ARF5 TUBA8 KIF21A KIF20B COG4 KLC2 KLC4 KDELR3 COG1 GBF1 MAN2A1 DYNC1LI2 KIF21B RABEPK VPS53 GOSR2 COPZ1 ARFGAP1 COG5 CYTH2 TUBA4B COPA SCOC TMED9 RAB43 GOSR1 CENPE COPZ2 TUBA1C PLIN3 COPE DYNC1H1 CYTH3 GCC2 KIFAP3 GCC1 COG6 ARFIP2 KIF6 ARL1 BNIP1 NBAS KIF3A DCTN3 RGP1 MAN1A2 KIF13B STX10 DCTN5	up	**
AMIT_EGF_RESPONSE_60_MCF10A	0.0034513	0.0325955	0.4317077	-0.4425845	-1.665407	34	DLC1 SOWAHC TRIB1 IER2 KLF7 CXCL2 INHBA HES1 IL6 JUN JUNB PTGER4 GLIPR1 SLC35D2 PDLIM5	down	*
GO_MYELOID_LEUKOCYTE_MIGRATION	0.0001234	0.0023006	0.5188481	-0.3178518	-1.665150	157	CXCL3 IL1A SWAP70 EDNRB PECAM1 IL1B CCL3L1 C5AR1 CD9 IL1RN IL23A ANXA1 PLA2G7 JAM3 SIRPA PDE4D CCL22 PTPRO BST1 THBS1 CCL3 CXCL2 CCL4 MIR24-2 SFTPD XCL2 FCER1G DUSP1 AKIRIN1 TGFB2 NCKAP1L FLT1 IL6 HRH1 RAC2 RHOG PTGER4 CCR7 DAPK2 CXCL5 CD74 VAV3 ITGA9 FPR2 CD81 LGALS3 CCR1 PDE4B CCL20 WDR1 KIT EDN1 MTUS1 MCOLN2 ANO6 GREM1 SERPINE1 C5AR2 CX3CR1 C5 TREM2 S100A8	down	**
REACTOME_ACROSOME_REACTION_AND_SPERM_OOCYTE_MEMBRANE_BINDING	0.0016401	0.0184231	0.4550599	-0.9425082	-1.664804	3	IZUMO1 CD9	down	*
GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_UP	0.0000607	0.0012737	0.5573322	-0.3161701	-1.664794	170	RAB11FIP1 SLC31A2 ARHGAP31 EDNRB PECAM1 SPN LRRC8C DCSTAMP RAPGEF2 PID1 SIK1 HCAR2 MYD88 CDC42EP2 IL1RN SCARF1 HEG1 ITGA5 FBXL5 MEFV DRAM1 VASP KLF7 MYO1B NFKB1 GPR85 CD302 N4BP1 PIK3R5 HCK LACC1 SH3BP5 KCTD12 ETS1 NXPE3 GMFG MALT1 LPCAT2 TNFRSF10B RRAS GSAP JMJD6 KCNA3 SOD2 GPR18 PDE4B	down	**
chr5p13	0.0052568	0.0443562	0.4070179	0.4328952	1.664708	57	PRLR DROSHA WDR70 GOLPH3 NUP155 C6 SPEF2 AMACR SKP2 AIG1P1 OSMR KRT18P31 RPS4XP6 TTC23L NADK2 FBXO4 SLC1A3 ADAMTS12 RAI14 C5orf22 DNAJC21 C1QTNF3 OXCT1 OFD1P17 RAD1 BRIX1 LMBRD2	up	*
GO_CYTOKINE_PRODUCTION_INVOLVED_IN_IMMUNE_RESPONSE	0.0017812	0.0195715	0.4550599	-0.3496414	-1.664238	86	HMOX1 SCIMP CD55 IL1B GAS6 SLC11A1 CD36 GATA3 IL18R1 TRAF6 IL10 TLR4 FCER1G SMAD7 TGFB2 IL6 CD160 MALT1 TBX21 CD74 TGFB1 CD81 MR1 IL18 IL18RAP NLRP3 KIT WNT5A BCL10 DDX21 SIRT1 NR4A3 CD226 CHGA TNFRSF1B TRIM6 ARG1 B2M	down	*
RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN	0.0000100	0.0002785	0.5933255	0.3469932	1.663127	312	LINC00342 BUB1B GGCT SORD TTK CDK4 RACGAP1 E2F8 GMPS PTTG1 ECT2 GPI GAPDH CCNB2 MCM4 SLC35E3 MCM2 TYMS CDC25A PRC1 DTL CCT6A MIS18A SHMT2 ZWINT MRPS35 COX11 LSM5 NME1 LDHB BZW2 MELK HMMR NUDT1 CEP55 KIF15 PCCB WASF1 TOP2A RRM2 PRKDC MRPL3 KIF11 KDELR2 CHEK1 MAD2L1 AHCY FBL RAB13 RAD51AP1 ETFA IDH2 CNPY2 DYRK2 CKS1B HPS4 NUSAP1 CDK1 SSBP1 POLE2 BIRC5 CCT3 ATIC GMNN GOT2 UNG NCAPG SNRPE LAPTM4B CHCHD3 ATP9A SPTSSA SSRP1 GINS2 ANP32E MARCKSL1 COPS6 CCT7 STOML2 IARS2 AHCYL1 HMGA1 RPA1 MCM6 MYO5C MRPS33 TBCA PRMT1 MCM5 NEK4 LRIG1 CCNG1 HAUS4 LSM4 DPH5 INTS8 GLO1 PRIM1 VDAC1 SNRPD2 SHCBP1 RAD51 TPGS2 PFKM OXCT1 NDUFA8 SMC2 MTHFD1 PAICS GPX7 APEX1 PPIA ENO1 TUBA1C LXN	up	***
GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN	0.0000823	0.0016390	0.5384341	-0.3138958	-1.663011	173	SASH1 EDNRB USP12 SOWAHC LTA4H SOX17 DDX6 SRSF7 GIMAP6 VAPA NFATC3 LACTB CORO6 CHMP1B AHRR MAP3K8 COX18 TMEM123 CRK MCL1 ZYG11B FLI1 ZADH2 FAM49B ID2 KLRD1 KBTBD4 TM9SF2 MYH11 MARK3 HCK MTPN ELF1 LRRTM2 EBAG9 HMBOX1 ETS1 ELOVL7 FERMT2 DDX5 NAA30 TSPYL1 RHOQ CD164 HIVEP2 STXBP3 NIPA2 AOX1 GLRA1 ABI3BP RTN4 ALDH6A1 DAPK1 STAM2 FAM126B KIF1B FCRL1 PAPSS2	down	**
GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP	0.0000712	0.0014515	0.5384341	-0.3108217	-1.662836	187	SC5D SNX10 PTP4A2 RCOR1 GTF2E2 PLEKHA1 BCL2A1 CD9 RRAGC UBL3 ASAH1 SRGN UBE2D3 EPB41L2 ARRB1 AHNAK LIN7C RNFT1 ITM2B PRKD3 ROCK1 OSTF1 SNIP1 ITIH5 RECK ARAP3 PLEKHB2 EPS15 KLRD1 PPP2R5C TM9SF2 IL7R SMNDC1 DEGS1 RNF149 KCTD12 IFNGR1 EEA1 SMU1 RAB8A SNX9 RHOQ PELI1 YTHDF3 VAMP4 RGS2 ADAM10 SERINC3 PPID HAUS3 VPS4B HNRNPK OSER1 B3GNT2 DNAJB9 DAZAP2 NABP1 EID1 RSU1 RAB2A PPP1CB PHYH TMEM30A HMGCS1 PRKCH	down	**
DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN	0.0008474	0.0111975	0.4772708	-0.3410377	-1.662813	97	MNDA PTPRE LPL LY86 EPB41L3 LILRB3 ADA BTG2 IFI30 ANXA5 GATA3 MCL1 KLF4 SELL JAM2 CD53 VAMP5 IL7R NINJ1 MN1 CSTA CCR7 GLIPR1 IRF8 CST7 KLF2 NKG7 GPX3 CEBPD MS4A4A FGFR1 RPL18A IL16	down	*
MIR141_3P	0.0000005	0.0000211	0.6594444	-0.2904125	-1.662427	349	SEMA6A DLC1 OSBPL11 TRHDE P2RY1 SIK1 ZBTB34 TMEM170B EGR2 HCAR2 IBA57 PAFAH1B2 NR3C1 CBL ZEB2 ERG EDEM1 B3GNT5 FOXA2 C1orf21 HIPK3 KLF6 GLS SLAIN2 FOXJ3 PLXNA4 LHX6 TNS1 TMEM41B ZEB1 ZYG11B ARRB1 DUSP3 RNFT1 ZCCHC24 PEG3 MED6 VRK2 SOCS5 MYRIP SPAG9 NPAS3 KCTD20 CCND2 ELK3 PLEK ARL4A RSL24D1 KIAA0408 CYP26B1 NCKAP5 IKZF5 TGFB2 C2orf69 CREBRF HCAR3 RAB8B PIKFYVE TMTC1 SLC14A1 MN1 APBB2 CSTA PRKCE GRB2 CREB1 TSHZ3 TTBK2 TCF4 YTHDF2 IFNAR1 IRS2 MAP3K2 ATXN1 CLASP2 GNA13 LTBP1 KIF17 PHLPP2 MBNL1 MLANA INO80D MIER1 ABL2 FKBP1A ITPRIPL2 CDC42EP3 TIAM1 TTLL7 PTCH1 IPO5 EPHA2 DAPK1 LYSMD3 RASSF8 ARPC5 FNIP2 FAM126B C21orf91 DOCK4 GSG1 SFPQ WDFY3 SPOPL MIER3 HSDL1 ARHGEF18 SUGT1 PLAG1 CHP1 CDC14A GJC1 HMGCS1 SLC19A2 MYH10 DCUN1D3 RB1CC1 PIAS2 FAM160B1 UBE3A C11orf54 KIDINS220 GABPB1 ATP8A1 DR1 WWTR1 CNTN1 SLC23A2	down	***
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.0023170	0.0239777	0.4317077	-0.3670355	-1.662292	67	SC5D CXCL16 PPARG CPEB2 LPL IDI1 HMGCR CD9 STARD4 SEMA3B ANXA5 FABP5 PLAUR ATF3 PNRC1	down	*
OSMAN_BLADDER_CANCER_UP	0.0000005	0.0000204	0.6594444	-0.2870381	-1.662244	370	MS4A7 PTP4A2 COQ2 CD44 TMOD3 SAMHD1 KIAA1109 CITED2 INPP5A USP47 ACER3 DNAJB14 SNHG5 MALAT1 SGMS2 EIF5 MED19 LAIR1 C1orf162 SLC25A37 ZFYVE16 SPI1 TCF7L2 RAB14 ZYG11B CDADC1 AGO3 LRRC57 SCP2 LIN7C VASP TMED5 CEBPA SOCS2 ATP6V1D TPP1 CTSD SSH1 RBMS1 PTPRC CEP57 ACTR3 PRF1 FCER1G CCSER2 SMAD7 BCLAF1 KPNA3 USP16 PIAS1 NCKAP1L ELF1 PHACTR2 APPL1 HCFC2 SF3B1 CD48 KCTD12 DESI2 GLUD1 FOXN2 ENPP4 PIK3R1 HSPA13 PTGER2 TRAK2 DLEU2 MOB1A BLOC1S6 RHOQ AGPS KLF2 AZI2 TNFSF13 RUNX3 ALDH3B1 NKG7 TGFB1 STRN KHDRBS1 EWSR1 MAP3K2 ATXN1 TMEM107 LGALS3 KYNU SERINC3 MR1 MBNL1 INO80D INTS6 PDLIM5 CHURC1 NBN SRP72 MS4A4A HSP90AA1 THAP6 RIPK2 ARIH1 ALDH2 HAVCR2 MEX3C PSME4 STK4 CTSC ZDHHC5 LYST CCND3 IQGAP1 RNH1 SUGT1 CRTAP SPPL2A SVIL ATP11B UBA6 LNPEP TGOLN2 FAR1 CALR SRSF11 BSG WDR41 UBE2W NOL9 IER3IP1 RMDN1 SCAF11 SLC25A40 ACTR1A RAD21 CRIPT RNU6-1016P KLHL9 NKTR SECISBP2 FNIP1 APOBEC3C IMPACT AKAP13 NFKBIZ CYP1B1 BICD2 FAM107B ZC3H7A C3AR1 CPNE3 PNISR LDLRAD3 SRP19 JAZF1 MTDH SCAMP1 RASA2 ANKRD17 CD47 SNRNP48 PTPN22	down	***
GSE22886_NAIVE_VS_MEMORY_TCELL_DN	0.0001768	0.0030903	0.5188481	-0.3131272	-1.662027	180	ACP5 IL17RB GPR15 CD44 TMOD3 CITED2 SLC39A8 EDEM1 RAP1A TMEM123 FLI1 EVI2B LIMS1 ITM2B FUT7 DOCK9 UXS1 CCND2 ELK3 DSTN TP53BP2 DEGS1 SEC31A LMBRD1 PHTF2 PPP6C AQP3 HECA PSMA1 FOXN2 WTAP TSPYL1 YWHAZ TAGLN2 CALM1 HIVEP2 ICAM2 CR1 CCR4 TEX14 TPMT NFYC ORC2 N4BP2L2 CCR6 SESN1 ACAP2 EPHA4 TAB2 CCR9 MEX3C DUSP7 SNX15 SAMSN1 LPAR6 EHD4 EID1 DNAJA2 EIF4G2 CRTAP CMPK1 YWHAB KCMF1 MATR3 RAD21 RCBTB2 TRAT1 BMPR1A CBFB IVNS1ABP CBLL1 MFHAS1 ISCA1 KDM4C CAPG SLAMF1 AIDA CD47 CREBL2 PDS5A	down	**
KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP	0.0000000	0.0000000	0.9325952	0.3244974	1.662026	1128	SLC9A3 TRIP13 GRIK2 FOXM1 HELLS HJURP PKP2 RUVBL1 CDC45 TICRR PARPBP MCM10 FANCI TROAP CHEK2 BUB1B SYNPR PROM1 NEK2 COIL TRNP1 CCNB1 DNAJC12 CCDC34 SOX2 CENPF TIMELESS POLQ UBE2T MPP6 MND1 KIF18B PKP1 TTF2 CLGN NDC80 RAB3IP PRIM2 DEPDC1 SLC25A21 SORD BRCA1 DEPDC1B CDCA7 C12orf66 ZNF138 TTK GINS1 CDCA2 RACGAP1 IQGAP3 E2F8 GTSE1 KIF14 NOL12 ANLN AC011043.1 ASPM PLK1 NUF2 YEATS4 KCNQ5 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 TRIB3 FIGNL1 UHRF1 MCM4 MCM2 RAD54B TYMS XPNPEP1 CDC25A UMPS MYBL2 PRC1 ORC1 CCNF PLS1 DTL DYNC1I1 MCM8 XPO5 KIAA0895 GINS4 NCAPD2 ZWINT CDT1 ZNF107 CCT2 SPDL1 TAMM41 FAM220A RANBP1 CLDN1 MELK HMMR EXO1 C19orf48 SMARCC1 XPNPEP3 KIF23 CEP55 CHAF1A GFPT1 PAQR4 MKI67 ZNF850 HLTF EMC9 KIF15 MRPL15 FBXO43 KNTC1 RHNO1 BUB1 FANCA AUNIP TOP2A IDO1 CENPL PUS7 BPHL AURKA EME1 NUP155 C1orf226 POLA2 SAE1 ATR KIF2C MCM7 E2F2 POC1A MPHOSPH9 CPD RRM2 CDCA5 PRKDC WDHD1 HOOK1 RAD54L DCDC2 KIF11 PASK FANCD2 GPSM2 MCM3 CHAF1B LMNB1 CDC25C FAM162A LIG1 BRI3BP POLR3C KDELR2 CHEK1 DNAJC9 ORC6 MAD2L1 CKAP2L TRMT61B NFYA CENPO PFKP RAD51AP1 DCTPP1 PRMT6 PKMYT1 BRIP1 ZNF507 RAD18 BLM PPP5C GLE1 CCDC138 DBNDD1 COQ9 SKP2 PARP1 GEMIN4 INCENP THOP1 KNSTRN NCAPG2 CMAS FRMD5 NUSAP1 URI1 ASF1B CDK1 POLE2 KCNE3 EXOSC2 CENPJ DIDO1 UCK2 BCAS4 RFWD3 CENPH BIRC5 ESRP1 ABHD17C C1orf112 GMNN NBPF3 POC5 E2F1 NCAPG STX18 STEAP1 DNA2 KIF2A DHX33 PSAT1 FSBP NEIL3 FEN1 SSX2IP NUP205 POC1B SLC35F3 ATAD3A ITPR3 PA2G4 RNASEH2A KPNB1 RANGAP1 NET1 MYO19 SLAIN1 DNMT1 FANCG EDEM3 TUBG1 DLGAP5 GALK2 TRMU PUS1 TACC3 SNRPA MBD4 TUBB2A OSBPL3 NGFR SLC37A4 UBE3D SUDS3 SSRP1 TMEM237 TK1 DTYMK MYBBP1A GINS2 GEMIN5 ANP32E PKP4 TCEA1 KIF20B SRD5A3 ASNS GFM2 TSEN54 CDK13 NUP85 ITGB2-AS1 CCZ1 SCNN1G SLC1A3 ATAD5 ELAC2 CDC7 EFCAB7 CENPV CKAP5 KLHL23 CDC20 CENPM PPP1R8 FBXO22 ACLY ZNF76 RPA1 ENTPD3 CDR2 ASRGL1 UBE2V2 MCM6 MGME1 CKAP2 SRPK2 DHX8 MCM5 USP21 ZRANB3 SNRPD1 MAB21L3 HAUS6 NEK4 FAM161A SLC35A3 SRSF1 C1orf109 GINS3 AATF DUS4L PIGX RCC1 HAUS4 SLC1A5 LSM4 WDYHV1 ATAD2 TSR1 CEP152 DUS2 NUP62 CEP85 SUV39H2 MSH2 ME1 RCN3 PRIM1 PRR11 ZNF93 DDX54 RFC5 TUBGCP4 USP39 ABCF2 WDR4 AP001372.2 HK2 RAD51 FARSB ZWILCH	up	***
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_UP	0.0001367	0.0024979	0.5188481	-0.3159784	-1.661975	164	SC5D DENND5A SIK1 HSD17B11 SAMHD1 LDB2 YPEL5 AGTPBP1 PTPRM PDE4D ARRB1 ITPRIP AHNAK PSTK DENND6A KLF4 ST7L DUSP1 RNF139 UBASH3B PIK3R5 MAFF C16orf54 SNN TBC1D5 AREG SOCS3 AQP3 JUN MAP4K4 JUNB ATXN1L SKIL OGFRL1 TAGLN2 FOS PTP4A1 ZNF669 TRAPPC10 BIN2 NAP1L5 FAM204A ADPRM GSAP TSC22D1 ZNF844 IRS2 KCNA3 DOK2 TOB1 RGS2 KAT2B HAUS3 CCDC69 CGRRF1 ARRB2 EPHA4 ZBTB25 TTC32 ITCH ZFAND2A PIEZO1 CFL2 MDS2	down	**
GSE360_CTRL_VS_L_MAJOR_DC_DN	0.0001547	0.0027678	0.5188481	-0.3199616	-1.661964	160	SIRPB1 SLPI FOXF1 GPR15 ADPRH PPARG FCN3 THBD SLC39A8 IL1RN TRIB1 IL23A BMP1 CD5 HSPB1 LITAF KLF6 CAMTA1 SERPINB9 ITSN2 IL10 DENND3 SOCS2 GMPR ID2 DNTTIP2 ARL4A VAMP5 SMNDC1 TDRD7 BTG1 S1PR4 SLC14A1 CCR7 FRYL PTGER2 RAB8A CELF2 RHOQ CDK17 SFTPC DUSP5 IRS2 PIM1 ATP6V0C SOD2 KYNU ETS2 CCR6	down	**
GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP	0.0004028	0.0061952	0.4984931	0.3694036	1.661960	164	CDHR2 STAC2 GPT PKP2 MCM10 ELOVL6 NEK2 APOLD1 KIF18B CDCA7 RACGAP1 ANLN ABCA12 BCAS1 AURKB CENPA TPX2 MYBL2 MIS18A MYL6B MKI67 DCBLD2 KIF2C CHAF1B LMNB1 XXYLT1 AIMP2 BRI3BP TXNDC5 CKAP2L TIMM50 PERP EEFSEC IDH2 MBOAT1 SLC25A10 PPIL1 CDK1 E2F1 CTXN1 KPNB1 NET1 CRLF1 CCNE1 DLGAP5 NEK10 NADK2 LMF1 ROGDI DNM1 TYRO3 LSM14B CKAP5 TUBG2 BEND6 CDR2	up	**
KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN	0.0001483	0.0026729	0.5188481	-0.3133039	-1.661606	182	LPIN2 DENND5A SNX10 CLDND1 KCTD9 TTC7B CD44 ST3GAL6 MYADM AQP9 BCL2A1 FGR ANXA1 ENTPD1 RAB33B LITAF KLF10 SERPINB9 IL18R1 CRTAM SRGN TXN AHNAK SORBS1 CASP1 YBX3 SOCS2 CTSD LAPTM5 ITGAX HOPX ID2 CCL4 RECK PRF1 KLRD1 MBD2 DSTN MAPRE2 EMP3 CD160 GABARAPL2 SLC35E4 EEA1 DAPK2 GMFG RHOQ KRTCAP2 CHPT1 LGALS3 FCGRT IL18RAP ACTB S100A4 ADORA2A KLRK1 RORA CCND3 RSU1 NR4A2 ITGAL ITGB1 ALG2 POLR2L RPA2 ATF6 DOCK5 FAM89B CD4 CASP3 GZMB RNF19B MYO1F KLRC1 EMP1 KLRG1 TERF1 GZMK IL10RA	down	**
GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_UP	0.0000655	0.0013528	0.5384341	-0.3155431	-1.661493	170	ARHGAP31 OLR1 FABP4 CALCRL MEF2A NEDD9 DSCAML1 SLC25A17 EIF1 FOXP1 SLC7A11 SERPINB9 FOXJ3 FAM122A SLC25A37 IL10 SLC12A4 KLF9 STK17B CLDN5 CDKN1A P2RY2 GPR85 DUSP1 WDR48 SPRYD7 KREMEN1 GPBP1 JUN HPGDS STAT4 EPC1 IFRD1 IRF8 GYPC REL ACSL1 FOS GIMAP1 AZIN1 GLRA3 TGIF1 KCTD10 FEM1B CD86 IRS2 AOX1 TPMT KCNA3 ZNF296 ETS2 ICAM1 PDLIM5 SLC25A20 PTCH1 TRAF1 PKNOX2 LTBP3 MMD MT2A HTRA2 BHLHE41 CHIC2	down	**
GO_SPINDLE_ASSEMBLY	0.0015516	0.0176853	0.4550599	0.3957219	1.661379	93	SPICE1 CHEK2 NEK2 RACGAP1 ASPM MSTO1 PLK1 AURKB TPX2 MYBL2 HAUS5 KIF23 KIF3B MAP10 AURKA TPR CENPW KIF11 GPSM2 CEP97 BIRC5 KIF2A SPAG5 KPNB1 CEP63 CEP192 CDC20 AAAS CHMP4C HAUS6 RCC1 HAUS4 TUBGCP4 CHMP1A CHMP2A GOLGA2 MAP9 CLASP1 DRG1 DYNC1H1 WRAP73 FBXO5 TUBGCP2 LZTS2	up	*
HALLMARK_SPERMATOGENESIS	0.0031267	0.0300672	0.4317077	0.3990646	1.661369	87	NEK2 COIL CLGN TTK CCNB2 SCG5 MAP7 RPL39L BUB1 AURKA GPR182 KIF2C TEKT2 PHKG2 OAZ3 TOPBP1 CDK1 EZH2 HSPA4L NPHP1 MTOR PCSK4 IL12RB2 GAD1 NEFH STRBP SLC2A5 YBX2 LPIN1 NOS1 MEP1B VDAC3 SLC12A2 ALOX15 NCAPH PARP2	up	*
GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN	0.0005303	0.0077386	0.4772708	0.3657445	1.660781	177	KIF20A CDC45 MCM10 NEK2 UBE2T PRIM2 BRCA1 TTK E2F8 ANLN ASPM CDCA8 AURKB CENPA IGLC7 ECT2 CDC6 CCNB2 TYMS PRC1 CCNF DTL CISD1 CHAF1A MKI67 BUB1 TOP2A AURKA KIF2C CDCA5 GCAT KIF11 CDC25C LIG1 CHEK1 MAD2L1 PERP GNPDA1 INCENP CKS1B CDKN2C NUSAP1 ASF1B CDK1 BIRC5 GMNN EZH2 DLGAP5 TACC3 KIF22 TK1 GALNT3 FHL2 RHD	up	**
GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP	0.0000647	0.0013372	0.5384341	-0.3123497	-1.660757	175	ARHGAP31 GAPT PLEKHF2 QKI CDC42EP2 EPB41L3 TGFBR2 FAM49A IL23A ADA RAP1A MTF1 MAP3K8 RNF144B LAIR1 NFE2L2 EPM2AIP1 ARRB1 BIRC2 PPM1K PTAFR VASP STK17B THBS1 KLF7 CLIC4 TLR4 PNRC1 CCSER2 PIK3R5 HCK LACC1 HCAR3 SYNPO2 SOCS3 OASL DNAJA1 FOXN2 GRB2 RBM22 TNFRSF9 TNFRSF10B NDUFV2 ACSL1 MYL12A RIN2 PIK3AP1 EHD1 FPR2	down	**
MORF_PRKDC	0.0004154	0.0063438	0.4984931	0.3692216	1.660568	161	TRIP13 RUVBL1 BUB1B MCM2 TYMS SRPK1 SHMT2 ZWINT RUVBL2 NUDT1 SMARCC1 CHAF1A CCT5 PRKDC TRRAP RAD54L MCM3 ACTL6A PKMYT1 CAD ALG3 COQ9 THOP1 CDKN2C ANAPC5 PABPN1 SSBP1 GOT2 NPM3 KXD1 DNMT1 ILF2 SNRPA SSRP1 MLEC TCEA1 DNAJC11 PSMD2 CDC7 BRD8 MCM6 MCM5 TFAP4 AATF TXNL4A NUP62 PRPF31 BMS1 SNRNP200 VDAC3 ZNF131 RPN1 MRPS27 GPN1 MZF1 AKR7A2 XPO6	up	**
GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP	0.0001245	0.0023184	0.5188481	-0.3127831	-1.660518	174	CD52 CD101 OSBPL1A HHEX FABP4 CLEC3B CAT LY86 RASAL2 MEF2A VAPA CD9 AVPI1 TXNIP DPEP2 ATP2B1 ECHDC1 REV3L TNS1 GRN APOC1 ZYG11B SORBS3 FABP5 CFD PPT1 CPVL SLC7A8 ZADH2 CEBPA CADM1 CD302 TAF9 BACE1 CDKN2AIP CNRIP1 RPS6KA2 PRCP TECR CCNY SNX29 PABPC4 WDR7 GAS2L3 GRSF1 TIMP2 CD86 LGALS3 CLEC2B PLA2G15 GPX3 HAVCR2 AMZ2P1 ACADM CD1E FAM13B STARD13 CRTAP TREML1 C5 TREM2 ATP1B1 CBR4	down	**
MIR487A_3P	0.0014849	0.0171156	0.4550599	-0.3469962	-1.660413	89	CLEC12A ZCCHC2 MTMR10 DYRK1A MOB1B ZEB2 BTG2 NLK PDE4D GPM6A KCNMA1 ATL3 SMAD7 LRRTM2 APPL1 MAGI2 LRCH1 SNX2 SP3 PDZD2 AGFG1 AZIN1 STXBP3 APLP2 LEKR1 ST6GAL2 KIF1B ENY2 EVI5 ATF2 CRBN	down	*
GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN	0.0002171	0.0036770	0.5188481	0.3664069	1.660403	175	KIF1A CNGA1 ADH1C ELOVL6 PSPH BRCA1 RACGAP1 ANLN CDCA8 CCNB2 MCM2 MYBL2 PRC1 HAUS5 RANBP1 BZW2 NUDT1 F2RL1 TOP2A MCM7 MPHOSPH9 MRPL27 CDC25C SLC12A7 RBP1 CHEK1 MAD2L1 AHCY PFKP XRCC1 CKS1B DRC1 NUSAP1 CDK1 BIRC5 SRCIN1 TCF20 PSAT1 PDK1 EZH2 SEMA4F COL1A2 PSME2 KIF22 SSRP1 MYBBP1A MMP7 HLA-A ZBTB7B CENPK CPSF4 PSMB3 CDC20 MRPL41 CKAP2 NFE2 CBR1 AP2S1 CCNA2 MRPL55 RFC5 LPIN1 RAD51 UQCRQ GOSR1 NPTX1 DHRS3 FRMD6	up	**
GO_NEGATIVE_REGULATION_OF_SECRETION	0.0001773	0.0030974	0.5188481	-0.3190497	-1.660227	159	FFAR4 RAB11FIP1 FOXF1 HMOX1 ADTRP IL1B P2RY1 STXBP6 HMGCR GAS6 CD22 ANXA1 MIR146A CARD16 ADA RAP1A RAB33B ANXA5 PPP3CA RGCC SFRP1 SRGN IL10 TACR2 REST KLF7 DPH3 MIR24-2 FRMD4A PTGER3 INHBA GNAI2 VAMP3 NOTCH1 CARD8 PTGER4 OSM CD34 CD74 STXBP3 SERPINB1 LRRC32 CRY1 SYT11 VPS4B NLRP3 EDN1 NRG1 PSMD9 ENY2 BANK1 PIM3 KALRN ACVR1C C5AR2 FKBP1B	down	**
MORF_CSNK2B	0.0000472	0.0010314	0.5573322	0.3519322	1.659657	246	PDCD6 COA1 GGCT CDK4 GMPS GPI ESPL1 EIF3B CCT2 DCTN2 RUVBL2 SDHA EEF1E1 CCT5 CBX3 NDUFS2 MCM7 FBL COMMD4 ANAPC5 HDGF SSBP1 AP3D1 CCT3 ATIC KIF2A LARP1 FEN1 KXD1 SNRPE DAP VBP1 UQCRFS1 CDC23 SNRPA LMNB2 TUBB2A HDAC1 TCEA1 CLTA DAP3 SLC4A2 JTB CCT7 ACLY PRMT1 TMEM147 SRSF1 HAX1 POLR2I SLC1A5 LSM4 PSMB4 SF3A2 EIF3K ALG8 NDUFV1 AP2S1 RER1 GLO1 ATP6AP1 DOCK3 BANF1 VDAC1 SNRPD2 PDAP1 PRPF31 UQCRC1 SEC13 COX5B MRPL9 SRP9 SNRNP200 ACP1 TMED9 NDUFS8 UBAP2L EIF4G1 CHERP TBL3 PTOV1 GPN1 SF3B2 COX6B1 MAP2K2 LYPLA1 COPE AKR7A2 DRG1 DGUOK FAM120A CLPP HUWE1 NHP2 CS SEC24C HNRNPAB SRSF9 PPP2R1A CALM3 COX6A1 DDX49 MAEA FIBP XRCC6 PSMD8 ACOT7 COX6C PRRC2C PPM1G BUB3 ATXN10 HNRNPUL1 RAC1 TRIM28	up	**
GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN	0.0001277	0.0023696	0.5188481	-0.3124882	-1.658952	174	SIRPB1 SMAD6 LIMS2 ACP5 IL1A HMOX1 MCOLN1 OSBPL11 PECAM1 FABP4 SNX10 THBD NEDD4L GPCPD1 TGFBR3 IL1RN AVPI1 ECHDC1 PICALM ABCG1 KLF10 ATP6V1B2 TBC1D9 UHRF1BP1L KLF11 PDE3B NR1D2 IRAK2 AXL ATP6V0D2 PLEKHB2 CPT1A PRICKLE2 USP16 HSDL2 ELF1 UTRN MED30 PTGER2 ATP13A3 SNX9 ECI2 SORT1 NIPA2 VAV3 NR2C1	down	**
MIR154_3P	0.0017435	0.0192232	0.4550599	-0.3482454	-1.658880	88	CLEC12A ZCCHC2 MTMR10 DYRK1A MOB1B ZEB2 BTG2 NLK PDE4D GPM6A KCNMA1 ATL3 SMAD7 LRRTM2 APPL1 MAGI2 LRCH1 SNX2 SP3 PDZD2 AGFG1 AZIN1 STXBP3 APLP2 LEKR1 ST6GAL2 KIF1B ENY2 EVI5 ATF2 CRBN	down	*
GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_UP	0.0000934	0.0018212	0.5384341	-0.3116934	-1.658878	177	OLR1 OSBPL11 CAT LRRFIP1 LY86 RTN3 CITED2 QKI CTDSP1 MKNK1 CD9 PILRA TXNIP DPEP2 TACC1 PBX3 ABHD6 PPP3CA CD37 EPB41L2 ZMIZ1 BST1 RNFT1 PRKD3 SLC7A8 KLF7 ITPK1 CARS2 HTT FKBP15 LMBRD1 SIAH1 HGSNAT NCKAP1L TBC1D5 RPS6KA2 ARHGAP17 CDC40 IFNGR1 PIK3R1 APH1B CACYBP CD74 KIAA0232 VAMP4 ADAM10 HELZ SELPLG RPP30 FKBP1A MS4A4A MTO1 ITGAE ALDH6A1 SLC2A9 BRWD1 IFFO1	down	**
GSE29614_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_DN	0.0025350	0.0256637	0.4317077	0.3915378	1.658860	99	GPR156 FAM83B GRIK2 HOXD8 RGMB-AS1 TTK BRSK1 TMEM254-AS1 DTL KHDC1 DNAI1 WDR62 GPR37 CBLC ZNF112 FSD1 HHIPL1 SOX11 SPC24 GRHL2 SYMPK APLP1 DMGDH NCAPG STEAP1 KSR2 PRR22 UPP2 COL5A2 TSPO2 AKAP8L GINS2 CHRD KCNB1 CD2BP2 MMP24 FRY-AS1 ZNF257 TMC2 FRZB CNTNAP3 BFSP2 C4orf46	up	*
GO_IMMUNE_RECEPTOR_ACTIVITY	0.0010929	0.0136331	0.4550599	-0.3377428	-1.658573	100	GPR17 IL17RB CD44 CCRL2 C5AR1 IL1RL1 LIFR FZD4 IL18R1 EPOR MPL FCER1G IL7R HLA-DQA1 CD160 IL2RB IFNGR1 CCR7 ACKR3 CD74 CR1 CCR4 IFNAR1 KLRC4-KLRK1 CCR1 MR1 IFNLR1 CCR6 IL18RAP CXCR4 CCR9 KLRK1 KLRF1 CSF2RB C5AR2 GHR CTSH CX3CR1	down	*
GO_POSITIVE_REGULATION_OF_ALPHA_BETA_T_CELL_ACTIVATION	0.0036402	0.0338317	0.4317077	-0.3862081	-1.658123	55	CD55 TGFBR2 IL23A RHOA ANXA1 ADA HLX SOCS5 PTPRC NCKAP1L CD80 CD160 CD83 MALT1 AP3B1 RUNX3 CD86 CD81 IL18 RIPK2 NLRP3	down	*
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS	0.0000129	0.0003466	0.5933255	0.3490474	1.657663	285	HMGA2 TRIP13 MDM1 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 PLK1 AURKB PTTG1 ESPL1 CDC6 TFDP2 RBBP8 ORC1 CCNF DTL ZFYVE19 CDT1 CDK5RAP3 SPDL1 CASP2 FBXO43 BUB1 GPER1 AURKA CBX3 TPR MAD1L1 CLSPN RRM2 PRKDC TOM1L1 HORMAD1 CDC25C SOX4 TOPBP1 CHEK1 MAD2L1 PSMD4 MDM2 MGA BLM PML CNOT3 CDKN2C CBX5 CTDSP2 CDK1 RFWD3 E2F1 PSMB5 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 CNOT2 PSMA5 PSME2 TRIM37 FZR1 PSMD2 CDC7 L3MBTL2 PSMB3 CDC20 CHMP4C CDK5RAP2 PRMT1 UIMC1 TFAP4	up	***
GO_PLASMA_MEMBRANE_RAFT	0.0012682	0.0152628	0.4550599	-0.3430151	-1.657253	95	HMOX1 DLC1 ADTRP EMP2 CAV1 CORO1C CDH13 BMPR2 ADCYAP1R1 PRKAR1A MAL CBL TGFBR2 SCN5A CD8A CAV2 MS4A1 LRP4 KCNMA1 PTGIS ADD1 HCK KCNA5 ADRA1A PRKACA CLN3 EHD2	down	*
GO_T_CELL_CYTOKINE_PRODUCTION	0.0037514	0.0345716	0.4317077	-0.4403523	-1.657008	34	CD55 IL1B SLC11A1 GATA3 IL18R1 TRAF6 SMAD7 IL6 MALT1 TBX21 CD81 IL18 IL18RAP NLRP3	down	*
GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN	0.0000913	0.0017945	0.5384341	-0.3130852	-1.656947	172	SLC6A4 TAL1 PTPRE HCAR2 CAV1 NUDT9 DYRK1A NR3C1 IL1RN PPP1R15B ABCG2 RAB33B MAP3K8 ZNF410 MCL1 TMEM38B FUT7 VRK2 CDKN1A ATF3 GCA ZDHHC20 NINJ1 ARHGAP17 MCMBP SYNPO2 ESD PDCD6IP ETV3 IRF8 IDS HOMER1 NAA30 MOB1A TMEM192 BLOC1S6 CD164 MRPL39 EXOC1 GNA13 HACE1 SERTAD1 RTN4 TAB2 G3BP2 CTSC ZDHHC5 KLRK1 LDLR PPP1CB HAT1 HTRA2 FHL5 CD70 CHIC2 TBPL1 ENDOD1 ITGB1 NOG PIAS2 UBE2N PDE7B	down	**
GO_REGULATION_OF_LEUKOCYTE_APOPTOTIC_PROCESS	0.0018090	0.0197920	0.4550599	-0.3606276	-1.656800	75	PTCRA GIMAP8 RAPGEF2 HCAR2 GAS6 ANXA1 ADA ADAM17 FOXP1 SLC7A11 IL10 SLC46A2 AXL FCER1G IL7R MIR17HG CCR7 DOCK8 TCP1 CD74 IRS2 PDCD1 LGALS3	down	*
REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	0.0000986	0.0019090	0.5384341	0.3573199	1.656779	207	BUB1B NUP107 CCNB1 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ESPL1 CCNB2 DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL NUP155 KIF2C MAD1L1 CDCA5 LMNB1 MAD2L1 PSMD4 CENPO SPC24 INCENP ANAPC5 CDK1 CENPH BIRC5 PSMB5 KIF2A ANAPC7 NUP205 DYNLL2 PSMC4 CENPP KPNB1 RANGAP1 CDC23 PSMA5 TUBB2A PSME2 TUBA3D TUBA8 CENPQ ANAPC1 PSMD2 NUP85 CENPK CKAP5 PSMB3 CDC20 CENPM CHMP4C DYNC1LI2 CENPT RCC1 PSMB4 NUP62 BANF1 ANAPC2 TUBA4B ZWILCH SEC13 CHMP2A CENPE LEMD2 UBE2C TUBA1C PPP2R5D CLASP1 NUP93 CHMP6 DYNC1H1 DSN1 PPP2R5E FBXO5 PSMB10 PSME1 NSL1 TMPO	up	**
GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP	0.0001325	0.0024429	0.5188481	-0.3119852	-1.656282	174	OSBPL11 THBD S1PR1 TBC1D2 GAS6 LAMP1 WWC2 RRAGC SLC36A4 RNF144B ABCG1 CD93 SPRY2 TMEM41B ATP6V1B2 FBXO8 RHOB LRP4 PTPN21 KIAA0513 LEPROTL1 CEBPA NR1D2 CDS2 TM6SF1 CD300C MFSD11 CPT1A NRBF2 ANXA3 PI4K2A CNRIP1 VWF GLB1 MYLIP PGD CD48 SLC10A7 APH1B WDR7 SLC3A2 ATP6V0D1 YPEL2 C19orf38 TIMP2 TESK2 TEC TMEM230 NQO2 RGS2 MFSD12 PLA2G15 ZNF438 MTO1 METTL21A G3BP2 HEBP1 LPAR6 EHD4 PHYH TMEM50A ZBTB16	down	**
WEST_ADRENOCORTICAL_TUMOR_DN	0.0000000	0.0000021	0.7195128	-0.2803294	-1.656222	455	SEMA6A IL17RB TEK SLC47A1 RASIP1 CSDC2 CD55 SFRP4 WFDC1 CLEC3B CAT WNT4 PID1 ARHGEF15 INPP5K ST3GAL6 FLVCR2 VAMP2 CTDSP1 MSRA ALAS1 SLCO2A1 USP47 ABCB1 CASP9 IER2 CCNL1 APOD EIF4A1 LTBP4 SEMA3B RAPGEF4 KCNK3 CSRP1 TMEM204 BTG2 PRELP ABCG1 KLF6 NR4A1 JAM3 SIRPA TNS1 AOC4P APOC1 FOXC2 SORBS3 ATP10A RHOB CFD AHNAK CASKIN2 SRSF5 SORBS1 FMO2 KLF11 PARVB GMPR LAMC3 HOPX AXL CD302 DUSP1 CUL5 PTGIS MAFF PTH1R KCNA5 PKIG MYLIP ID4 CREM PHACTR2 LAMB2 CNNM2 GLUD1 CYP2A6 JUNB PTGER4 PODXL LYRM1 DDX5 THUMPD1 LUZP2 NPR1 RASSF2 CD34 FOS UBB KLF2 TNFSF13 RBKS FOSB IRF5 CBFA2T3 LRRC32 KCNN2 AOX1 MEIS3P1 FAXDC2 CD81 PPIG TOB1 KYNU PLEKHO2 SPOCK2 TCF7L1 TAGLN TSPO SOD3 GEM ICAM1 SF1 CALHM2 SCN7A LMOD1 CEBPD TPT1 MFAP5 EIF4EBP3 TOB2 ALDH6A1 PTCH1 EPHA2 RBMS3 PARVA TTC19 RORA RHOT1 MT2A CNN2 EHD3 MS4A2 EGR1 ACSM5 DKK3 NR4A2 EIF3L ZYX NUP88 ZFP36 FAM53B ADAMTSL3 MT1E SV2B ABHD14A PEBP1 PLN IRF1 RCBTB2 ADH1B SLC23A2 TPSAB1 CEP68 SIRT1 NR4A3 IRF4 LRP1 SYDE1 ZNF331 MEPCE SLC25A28 FBLN1 PLEKHO1 CCDC85B HDDC2 MT1X CDC42EP4 ALDH3A2 MYLK	down	***
GO_NEGATIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	0.0011500	0.0141739	0.4550599	-0.3439661	-1.656108	92	FOXF1 HMOX1 CD55 CLEC12B CD22 ANXA1 RNF125 HLX SERPINB9 GRN CRK IL10 SOCS5 PTPRC SMAD7 IL7R C4BPB TGFB2 APPL1 SEC14L1 RC3H1 TBX21 CR1 TGFB1 LGALS3	down	*
GO_REGULATION_OF_ORGAN_GROWTH	0.0017907	0.0196590	0.4550599	-0.3554869	-1.655921	78	SLC6A4 RBP4 TGFBR3 TGFBR2 TBX2 WWC2 CACNA2D2 LATS2 HLX FOXC2 YBX3 TBX5 MIR17HG RBPJ NOTCH1 SAV1 PIM1 MEIS1 GATA6 RGS2 FGF2 ACACB STK4 EDN1 PTEN FGFR1 MIR548C ZFPM2 DUSP6 MAPK1 NOG	down	*
MIR8089	0.0008049	0.0107468	0.4772708	0.3762494	1.655822	133	EGLN3 PCDHGA10 PPP1R1B CPLX2 PCDHGA9 PCDHGA5 TTF2 TOX3 PCDHGA7 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 RANBP1 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 WDR72 CAPN12 ABCB9 CNGB1 NAA40 OSBPL7 FBXO41 KSR2 PCDHGA2 ZNF687 NRIP2 MAT1A NR6A1 PCDHGB1 ABCC10 BCL2L1 ENTPD3 ANKIB1 SLC38A7	up	*
GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_DN	0.0000983	0.0019057	0.5384341	-0.3110468	-1.655437	177	OTUD1 KLHL8 BACH1 CRY2 INPP5A NR3C1 ZBTB2 FAM49A DENND2C NUMB LATS2 CHMP1B TMEM204 TTYH2 KLF6 SETD3 RHOB ARRB1 CCDC82 LEPROTL1 CDIP1 RRM2B KLF7 MARVELD1 CDS2 ELAC1 SMAD7 DEGS1 RPS6KA2 SERTAD2 RYBP PDCD6IP ETV3 ETS1 CELF1 SHOC2 BAG5 RASSF2 LETM2 RNF146 PNPLA2 PHF3 CD1D KCTD10 TEC PIK3C3 TAGAP NBEAL1 RGS2 INO80 IER5 DAPK1 RBM48 RASSF8 TTC28 DNAJB9 RSU1 SMAD4 MAN1C1 SPPL2A TMEM43 LNPEP PATL2 RNF167	down	**
GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN	0.0003732	0.0058495	0.4984931	0.3670420	1.655411	169	EGLN3 CCDC34 CENPF DDIT4 ANKZF1 TRIB3 SPINT2 CDC25A CCNF DNAH14 RUVBL2 EXO1 SPAG16 CENPW WDHD1 PLTP CHAF1B DNAJC9 BLM GLE1 IDH2 PAK1 MRPL37 DTD1 CENPJ TRAP1 MRPL17 KIF2A FEN1 FADD LRRC42 SAPCD2 MAD2L2 RECQL4 POLR2H DNMT1 VBP1 DNAJC17 RHOC MTA3 TK1 DTYMK SND1 POLB YARS2 P4HA1 DHRS1 NFXL1 IARS2 ZCCHC17 FAF1 FBXO22 PPCDC MCM5	up	**
GSE3982_BASOPHIL_VS_TH1_UP	0.0001414	0.0025689	0.5188481	-0.3153593	-1.655096	167	SWAP70 LYL1 PLEKHF2 RTN3 NTM P2RY13 CD9 AGTPBP1 FRAT1 FGR RHOA SH2B3 EMILIN2 SERINC1 PBX3 CLK1 FBXL5 SCP2 SDCBP SORBS1 KLF9 MAP1LC3B PLBD1 PTPRC TLR4 DUSP1 RNF139 DSE PPP2R5A BCLAF1 LMBRD1 ARHGDIB HCK USP25 ZCWPW1 WSCD2 GRIA1 CD164 MBP ICAM2 SRSF6 BIN2 CR1 BTBD7 BAZ2B TSC22D1 GALC HBP1 EXOC1 N4BP2L2 SERINC3 PRDM8 IQSEC1 MEGF9 S100A4 MARC1 KIT FAM13B EIF4A2	down	**
GO_POSITIVE_REGULATION_OF_IMMUNE_EFFECTOR_PROCESS	0.0000961	0.0018681	0.5384341	-0.3127197	-1.655013	172	RBP4 FOXF1 HMOX1 SCIMP GATA2 PGC IL1B CD1C LAMP1 IL23A FGR CD36 ANXA1 CLCF1 RAP1A HLX GATA3 IL18R1 TRAF6 CRTAM TFRC PTAFR SOCS5 FAM49B CADM1 PTPRC TLR4 FCER1G CD80 IL6 CD160 RAC2 RAPGEF1 STX7 MALT1 TBX21 TNFSF13 CD74 TGFB1 AP1G1 CD1D ZBTB1 CD86 CD81 KLRC4-KLRK1 FCGRT UNC13D IL18 IL18RAP RIPK2 NLRP3 CD1E KLRK1	down	**
GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP	0.0002896	0.0047441	0.4984931	0.3657234	1.654606	173	FOXM1 CDC45 FANCI IGF2BP3 KIF18B CLGN SORD BRCA1 E2F8 TSPYL5 STIL COPB2 MIS18A MYL6B STAG3 RPL39L KIF15 TP53BP1 PCCB NUP155 POLA2 MCM7 LMNB1 SALL2 PSMD4 DSCC1 TSHR EFCAB11 CBX5 CEP97 TNFRSF21 FAT1 PLCH1 C1orf112 GMNN SPAG5 FADD TMEM231 KPNB1 CHCHD3 TAPBPL PSMA5 ARHGAP32 SAP30 DNMBP SND1 MARCKSL1 CDC20 ASRGL1 PEX5	up	**
SRF_Q6	0.0000720	0.0014655	0.5384341	-0.3078731	-1.654554	194	PPARG TMEM126A LRRFIP1 BDNF EGR2 CORO1C MYADM CITED2 FOSL1 CTDSP1 JPH2 KCNK3 RAP1A EMILIN2 PRELP PICALM FOXP1 KLF6 NR4A1 ZEB1 UBE2D3 CNN1 ROCK2 TNNC1 TRIM46 THBS1 NPR3 KCNMB1 ACTR3 ACTG2 MYH11 SRF CNTF TRIM55 PODN DHH JUNB RHOJ LYRM1 HERC1 RASSF2 FOS KRTCAP2 FOSB DGKG AKIRIN2 DUSP5 TGFB1I1 C16orf72 MRGPRF TAGLN MBNL1 PITPNA LDLRAD4 PDLIM5 DIXDC1 PTCH1 ACTB G3BP2 SIN3A KIF1B CNN2 RSU1 ATF4 STARD13 EGR1 CFL2 CDKN1B SVIL DCUN1D3 WNT5A LDB3 PLN MATR3 TES	down	**
GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN	0.0002032	0.0034905	0.5188481	-0.3116449	-1.654159	180	IL1B RAPGEF2 LRRFIP1 RBM14 BCL2A1 VAPA HPS5 ATP2B1 TRA2B LTBP4 ADAM17 RANBP9 PAQR3 SPRY2 CD58 EVI2B MAP2K3 ADO NFKB1 ATF3 CDS2 HOPX CCL4 MATK SH2D2A PPP2CA NSMAF PNO1 SERPINB8 CYCS RHOG TMEM251 IPO7 IFRD1 EEA1 SP3 IDS ZBTB24 REL DLEU2 ACSL1 HIVEP2 FEM1B DUSP5 NAB1 GNG5 ZNF267 PGGT1B MBNL1 GEM IL18RAP WDR1 CDC42EP3 NLRP3 UBE2D1 TRAF1 PSMD9 NUP160 FEZ2 NUP88 TUBA1A WDR47 BCL10 TSC22D2 GABPB1 KLHL9 SRR IRF4 DUSP2 CYP1B1 IVNS1ABP PNP RANBP2 TNFRSF1B GNL2 SUCLA2 EIF4A3 PSMD14 EZR AGO2 FASLG PTPN22 SACS SEC62 PRNP	down	**
GO_MEIOTIC_CELL_CYCLE_PROCESS	0.0007698	0.0103813	0.4772708	0.3772607	1.654146	129	TRIP13 BUB1B MND1 TTK ASPM PLK1 NUF2 PTTG1 ESPL1 FIGNL1 RAD54B CDC25A TDRKH NCAPD2 STAG3 FBXO43 BUB1 FANCA MSX2 TOP2A AURKA EME1 REC8 SYCP2 MSX1 NSUN2 RAD54L FANCD2 HORMAD1 CDC25C EME2 BRIP1 SUN1 CCNE1 TUBG1 RAD51D FZR1 SLX4 RAD50 ANKRD31 KLHDC3 MEI1 CDC20 TUBG2 FANCM	up	*
GO_REGULATION_OF_CELL_ADHESION_MOLECULE_PRODUCTION	0.0024364	0.0249161	0.4317077	-0.9362989	-1.653836	3	IL1B CAV1	down	*
HALLMARK_ESTROGEN_RESPONSE_LATE	0.0006256	0.0088367	0.4772708	0.3657668	1.653696	174	LTF TFPI2 PRLR PTGES KIF20A KCNK5 DNAJC12 FRK SORD TFF3 SLC27A2 STIL CDC6 RBBP8 AGR2 LSR CA12 CYP4F11 TJP3 LAMC2 TRIM29 TPBG TOP2A GPER1 SERPINA3 MDK SLC9A3R1 ASS1 PERP TST FLNB IDH2 DLG5 CXCL14 RAPGEFL1 GJB3 METTL3 ETFB FAM102A RNASEH2A HSPA4L ST14 SLC26A2 LLGL2 PKP3 MAPK13 SLC22A5 S100A9 CPE GINS2 KRT19	up	**
GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_DN	0.0006215	0.0088026	0.4772708	0.3745824	1.653590	139	PPM1H CCL19 HNF1A SLC16A14 BDH1 LHB C5orf46 TTC26 EFNA4 BCL2L14 XDH CDT1 SLC4A8 THBS4 SYCP2 POC1A RHOBTB3 HOOK1 AMACR SMYD5 DNAH8 KLHL35 SAMD10 DNAH6 MCTP2 WDR54 SPACA4 FAM98C ENPP3 FEN1 TMEM79 MTBP TMEM51 TAPBPL ARHGAP32 ZMAT5 CADM4 CASP7 PCDH9 ATP13A1 NR6A1 SLC26A1 RRP9	up	**
GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP	0.0000934	0.0018212	0.5384341	-0.3120635	-1.653304	173	SLC6A4 EPAS1 SECISBP2L FABP4 ENG TMOD3 SAMHD1 BAIAP2 MYD88 TLCD2 CHRNE PBX3 FOXP1 RGCC MTHFR RAB12 FOXO1 KCNMA1 NES STX3 VRK2 CCL4 PNRC1 WASF3 ARL4A CPT1A SH2D2A TANC1 KREMEN1 NCOA1 NSMAF MED28 COPS2 NXF1 INMT ST6GALNAC4 GSTO1 SNX2 CD83 STX5 TSPYL1 CD164 RUNX3 RELL1 PIM1 SLIRP BRI3 IST1 JUND ICAM1 TAB2 UBE2D1 TBC1D1 FBXO25 PSME4 STAM2 KATNA1	down	**
GO_REGULATION_OF_CELL_ACTIVATION	0.0000001	0.0000039	0.7049757	-0.2785105	-1.653075	480	SIRPB1 CD300LF FOXF1 HMOX1 CD55 GATA2 SPN IL1B MNDA PLA2G10 THBD FYN CAV1 PRAM1 FGF10 PRKAR1A CDC42 IL1RL1 CD9 GAS6 LAMP1 CD22 TGFBR2 IL23A FGR RHOA ANXA1 SH2B3 CLCF1 FBXO7 CD5 ADA CLEC7A MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 GRN SFRP1 WNT3A ZEB1 MAPK8IP1 TFRC PDGFA SLC7A2 ZMIZ1 IL10 NRARP DUSP3 BST1 SLC46A2 PTAFR THBS1 CEBPA CLECL1 SOCS5 MPL FAM49B CCL3 CDKN1A PTPRC SELP AXL ID2 TLR4 IGFBP2 SFTPD FCER1G SMAD7 PLEK INHBA IL7R UBASH3B CYP26B1 HES1 MIR17HG GNRH1 NCKAP1L CD80 IL6 CD160 PDE5A RAC2 TYROBP CCR7 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 RPS6KA1 DOCK8 AP3B1 TBX21 ZNF683 CST7 TIGIT PELI1 TNFSF13 RUNX3 TREX1 CD74 CR1 TGFB1 VAV3 AP1G1 CD1D ZBTB1 MILR1 CD6 TEC CYGB LRRC32 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23	down	***
GO_MEIOSIS_I_CELL_CYCLE_PROCESS	0.0033601	0.0318869	0.4317077	0.4033035	1.652890	79	TRIP13 MND1 PLK1 PTTG1 ESPL1 RAD54B CDC25A STAG3 TOP2A AURKA EME1 REC8 SYCP2 RAD54L FANCD2 HORMAD1 CDC25C EME2 BRIP1 SUN1 CCNE1 RAD51D SLX4 RAD50 ANKRD31 KLHDC3 MEI1 FANCM	up	*
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_UP	0.0008620	0.0113495	0.4772708	0.3755812	1.652881	133	STYK1 HHLA2 VWDE HELLS UGT8 IGF2BP3 TOX3 FABP6 PLD5 GLDC PLS1 AK8 GPX2 APOL1 POLA2 FNDC5 SP140L EGFR PERP STAT2 CDH3 NAPEPLD GBP5 SNCAIP CHST3 PSME2 ENAH ZNF239 ATG9B FHL2 IQCH POLB CCDC137 MDGA1 HHLA3 PARP14 RGMB SCO2 GBP1 TUBA4B GBP2 DNPEP WDR76 TRIB2 LINC00205 LRRC4C SLC35G1 RIMS1 NLRC5 KCNK6 DYNC1H1 TRAFD1 ST6GALNAC1 TMEM229B HINT1 ZNF276 PSMB10 RSAD2 BAK1	up	*
GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP	0.0001144	0.0021590	0.5384341	-0.3153536	-1.652061	163	MYO7B OLR1 DENND5A FCER1A ADRA1D SLC39A8 VAMP2 MAL CD1C ABCB1 DNASE1L3 TOE1 TRA2B LMNA EIF1 ITGA5 ADIPOR1 CLK1 MOAP1 MVB12B LRRC40 ELK3 DSE MATN2 GNAQ MAFF TOPORS BTG1 AREG ASNSD1 KIF13A UBQLN3 SRSF3 ETV3 GAS2L1 PTGER4 CCR7 IFRD1 N4BP3 NIPSNAP3B IP6K1 RUNX3 SRSF6 PKIA TGFB1 VAV3 JMJD6 CD6 TGFB1I1 ZNF136 GABARAPL1 TOB1 CCNH SESN1 RTN1	down	**
GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN	0.0002611	0.0043252	0.4984931	0.3652533	1.652030	171	NUP107 POLQ SORD ACAD9 SFXN1 UHRF1 HPS3 RCCD1 GSDMB MAGEF1 GOLPH3L KCNN4 EME1 SYNE4 FSD1 PKM EIF2AK1 LMNB1 B3GNTL1 LETMD1 CAPN12 BRI3BP SARS2 PSMD4 RAB13 PIH1D1 GEMIN7 NOL3 DLG5 C12orf75 CMAS NSF UCK2 NUDT2 ACP6 ZNF775 MAD2L2 SRD5A1 ANKRD39 UNC45A RHOC C12orf45 COMMD7 MTA3 ARF5 PINLYP TCEA1 FUCA2 NUP85 STOML2 ASCC1 ZNF558 GINS3 CEP152 ABHD10 UQCRC1 ZSCAN22 MICU1 CDK5 ETHE1 ALKBH6 CDC25B MRPL48 PARP2 CLNS1A CAMK2G JAKMIP2 SRI PSMB10 MTMR4 RNF144A TCEA3 DHX32 STXBP1 CS TXN2	up	**
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_CELL_CELL_ADHESION	0.0000432	0.0009568	0.5573322	-0.3094170	-1.651901	185	SIRPB1 CD55 IL1B FYN CD44 CAV1 CDC42 TGFBR2 IL23A RHOA ANXA1 CD5 ADA MAP3K8 HLX GATA3 SIRPA TRAF6 TFRC ZMIZ1 PTAFR CLECL1 SOCS5 FAM49B PTPRC IGFBP2 IL7R HES1 NCKAP1L CD80 IL6 CD160 ETS1 CCR7 PIK3R1 CD83 GRB2 MALT1 DOCK8 AP3B1 RUNX3 CD74 CD1D ZBTB1 CD6 CD86 PDCD1 CD81 KLRC4-KLRK1 ICAM1 IL18 RIPK2 NLRP3 HAVCR2 PAK2 KLRK1 TNFSF9	down	***
DORN_ADENOVIRUS_INFECTION_32HR_DN	0.0039914	0.0361780	0.4070179	-0.4389400	-1.651694	34	NR4A1 NFE2L2 MCL1 MAP2K3 SRSF5 SDCBP BCAR3 SGK1 JUNB CD83 KLRC2 EWSR1 EPHA2 NFKBIA CYTH1 HNRNPH1	down	*
GSE3982_MAST_CELL_VS_MAC_DN	0.0002307	0.0038812	0.5188481	-0.3146294	-1.651314	165	EPAS1 KMO USP12 FABP4 SLC6A12 ENG BAG4 PCOLCE2 EPB41L3 SCARF1 DDO PILRA TEX2 GGA2 DNAJB14 CD36 MAN2B1 MTF1 HLX TUBB6 PPT1 DAB2 SLC7A8 TMED5 RMDN3 SPAG9 CAPZA2 INHBA MATK CLIP4 ZNF706 RABGGTB CTSS PHACTR2 RAB8B SERPINB8 JUN MITF ZNF804A CXCL5 RHOQ PSMD12 FOXO3	down	**
RB_P130_DN.V1_UP	0.0018210	0.0198969	0.4550599	0.3896599	1.651184	101	HMGA2 SIM2 KIF20A CHCHD6 RACGAP1 AURKB CCNB2 SLC7A9 ORC1 B4GALT4 FAM220A RUVBL2 QTRT1 AURKA POLD2 ICA1 DCTPP1 FADS2 ANAPC5 CDK1 EXOSC2 BIRC5 ATP2A1 EFTUD2 PARS2 CRLF1 KIF22 RAD51D TK1 CASP7 SGSM3 CDC7 SULT1B1 ZNF428 RABEPK STMN3 POLR2I LSM4	up	*
GO_REGULATION_OF_LYMPHOCYTE_MEDIATED_IMMUNITY	0.0020130	0.0215362	0.4317077	-0.3278313	-1.650731	112	IL1B CLEC12B CD1C LAMP1 IL23A CLCF1 SERPINB9 GATA3 IL18R1 TRAF6 CRK CRTAM TFRC IL10 FAM49B CADM1 PTPRC FCER1G SMAD7 IL7R C4BPB IL6 CD160 STX7 MALT1 TBX21 TNFSF13 CR1 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT IL18 IL18RAP ARRB2 NLRP3 HAVCR2 CD1E KLRK1	down	*
GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN	0.0002059	0.0035218	0.5188481	-0.3137135	-1.650694	168	GPR15 USP12 SOWAHC OTUD1 TMOD3 CCRL2 ST3GAL6 HEATR5B GTF2E2 PAFAH1B2 TRIB1 ABCB1 SEMA6D FAM89A JAM3 NDEL1 TIPARP CSRNP1 PTPRO PPM1K PLAUR TMED5 CLIC4 GPR85 ATF3 VIM AXL CCND2 FRMD4A RNF139 HSDL2 PI4K2A RASGEF1B IL6 OASL CPEB4 RHOG ENPP4 GLIPR1 CGGBP1 TOM1L2 STXBP3 GSAP PDCD1 TAGAP TSPO SETDB2 SETD4 TRAF1 TMEM184B KATNA1 LYST TNFSF9 SYNPO2L THEMIS2 GIMAP4	down	**
GSE19198_CTRL_VS_IL21_TREATED_TCELL_1H_UP	0.0009047	0.0117379	0.4772708	-0.3268314	-1.650659	123	SLC6A4 SMAD6 TMEM100 FGD5 OSBPL1A MMRN1 SH2D3C KCNAB1 HBEGF SLC7A7 ZBTB8A TCF7L2 APOC1 SLC46A2 KCNK17 GCHFR SLC38A11 ID3 CEBPA RMDN3 EPM2A ID2 ALOX5AP SMAD7 INSL6 SPIN1 SCN4B CNNM2 INMT DNASE2 SKIL	down	*
GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP	0.0000832	0.0016541	0.5384341	-0.3134285	-1.650359	170	USP12 SIK1 RUNDC3B TMOD3 CALCRL CTDSP1 NR3C1 DENND2C ZBTB4 CNST PKD2L2 GM2A FOXP1 PAG1 LAIR1 PPP3CA BTG3 DENND6A PRKD3 GAPVD1 NR1D2 PPP2R5A IL7R PIK3R5 TP53BP2 FAM102B BTG1 CREBRF SGK1 IFNGR1 PTGER4 CCR7 DDX5 GPR183 RC3H1 CD7 RNF24 RUNX3 MTMR2 PHF2 CLCN6 SESN1 MIER1 IER5 ALDH2 TDRP ZNF471 FAM13B SMAD4 ZBTB40 CFL2 CDKN1B ATP11B ALG2 ATP1B1 ATP8A1 RCBTB2 SMIM4 KLHDC1 ITGA6 NEXN FAM78A CD226 CFLAR ZFP1 BICD2 RCAN3 ARID3B ATP10D LATS1 TMEM64 AMPD3 PADI2 RARA XPO4 VIPR1 RASSF3 BCL11B IFIT2 STAR AMZ1 VPS37B PPM1B IL27RA IL6ST NRIP1 AAK1	down	**
GO_MICROTUBULE_CYTOSKELETON	0.0000000	0.0000000	0.8634154	0.3232849	1.650306	1015	KIF1A CCNO SAA1 PKHD1 KIF12 KLC3 DDX11 CEP72 SPICE1 KIF20A MDM1 RUVBL1 CEP89 CDC45 DNAH2 RPGRIP1L BUB1B NEK2 ZNF12 CCNB1 CENPF STOX1 KIF18B NUDCD3 NDC80 MKS1 CCDC113 BRCA1 FANK1 TUBB2B TTK RACGAP1 BRSK1 GTSE1 IFT122 KIF14 SPAG17 CCDC14 CNTD2 ASPM STIL TTC26 CEP70 PLK1 IFT27 CDCA8 AURKB ECT2 ESPL1 CDC6 TPX2 GAPDH TFDP2 CCNB2 MCM2 DNAH3 PLEKHA7 PRC1 XRCC2 CCNF DTL DYNC1I1 CIB1 HNF4G CCT6A ZFYVE19 KIF27 SHMT2 CDK5RAP3 DNAH14 CCT2 DCTN2 SPDL1 WDR90 SPPL2B NME1 MICALL2 DNAI1 HAUS5 RANBP1 CEP250 WDR62 RSPH1 TTLL4 RUVBL2 HMMR DLG1 MAP7 KIF23 CEP55 BBS1 BOD1 CUL7 BICD1 KIF15 KNTC1 TSGA10 KIF3B CCDC13 CCDC77 AUNIP TOP2A FBF1 MAP10 CCT5 AURKA CBX3 ODF2 SFI1 IFT43 TPR SNCG KIF2C MAD1L1 POC1A AGBL4 WDR78 MPHOSPH9 TTLL12 MAP1LC3C TEKT2 FSD1 NSUN2 HOOK1 CCDC114 DCDC2 WDR73 KIF11 GPSM2 MCM3 YEATS2 WDR60 DNAH8 TOPBP1 CHEK1 NEK11 IFT172 CC2D1A MAD2L1 CKAP2L GAS8 KIF3C CBY1 TMEM63A DNAH11 SPAG8 RAD18 FNTB RABEP2 LRRC45 C2CD3 ERCC2 TRPV4 C4orf47 DLG5 PSRC1 INCENP MARK1 CCDC78 KNSTRN TTBK1 DRC1 NUSAP1 KRT18 LRGUK IQCB1 CDK1 CROCC DNAH6 CCDC61 CEP97 KIF5A SNX4 CENPJ DIDO1 BIRC5 CCT3 TTLL9 KIAA0753 JAKMIP1 POC5 E2F1 SCTR PSMB5 KIF19 ALDOB SPAG6 KIF2A ANKRD26 KIF7 SSX2IP CCDC88C DYNLL2 SPAG5 TTC23L POC1B RAB11FIP4 TRAF5 LCA5 DNAH5 CBX1 KCTD1 MAD2L2 KLHL22 FGFR1OP IFT52 RANGAP1 MZT2A MZT2B CEP63 BBS5 CCNE1 CEP192 EXOC7 TUBG1 DLGAP5 VPS41 DNAH7 NINL TACC3 CCDC151 TUBB2A TUBA3D KIF22 RAD51D IQCG DNM1 TUBA8 KIF21A CCDC146 HID1 PKP4 CLTA MAP6D1 KIF20B TEKT3 LRWD1 SMTNL1 NUP85 CEP128 JTB POLB TRAF3IP1 AAMP CCT7 CDC7 KLC2 SASS6 KLC4 TADA3 CENPV CKAP5 AGBL2 CDC20 WDR34 TUBG2 AAAS FTCD TTLL3 EFHC1 BCL2L1 UBXN6 CDK5RAP2 ODF2L DYNC1LI2 KIF21B EML6 TBCA CDC42BPG CKAP2 DNAI2 CAPRIN2 WDR35 HAUS6 DYNC2H1 NEK4 FAM161A TBC1D30 RAB3D TMUB1 KATNB1 NEURL4 SKAP1 ESRRA TTLL6 HAUS4 MARCKS TCHP CEP152 STRBP NUP62 CEP85 MICAL3 B9D1 ALMS1 APC2 TTC12 SHCBP1 NAV1 TUBGCP4 SYBU ICK CEP164 CCDC181 CLUAP1 NUBP2 DNAH1 HOOK2 TUBA4B CCDC88B RAD51 TPGS2 TRIP4 FBXW11 CHMP1A MARK4 NME7 CHD3 CDK5 AGBL5 CTTN TBCB BCAS3 CAMSAP3 CENPE DTNBP1 MAP1LC3A E4F1 SRPRB NEIL1 GOLGA2 APEX1 TTC30B CDC25B DCDC1 TUBA1C ZMYND10 MAP9 DNM1L RABL6 TTLL5 CLASP1 GSDMC BRSK2 TMEM201 KIF24 MAP2K2 NLRC5 ROR2 KIAA0586 MLLT11 DNAL4 UNC119 CEP290 SHROOM1 USP20 DNAAF1 DYNC1H1 MAK TEKT1 WRAP73 KLHL42 WDR63 BAG2 RPP25 PLK4 GSK3A FAM92B RUSC1 FAM110C PRPF19 AKAP9 PCNT DSN1	up	***
GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY_COUPLED_TO_CYCLIC_NUCLEOTIDE_SECOND_MESSENGER	0.0002430	0.0040614	0.5188481	-0.3209379	-1.649793	145	RAMP3 AKAP5 LHCGR ADCY9 P2RY1 GPR65 ADCY4 RAPGEF2 RAMP2 CALCRL ADRA1D TBXA2R S1PR1 RXFP1 MARCO PDE2A ANXA1 SSTR1 ADRB1 ADRB2 PDE4D PTGIR GRK5 NPR3 PTGER3 GNAQ GNAI2 PTH1R S1PR4 ADCY2 WASF2 HRH1 ADRA1A PALM PTGER4 PTGER2 GPR37L1 GPR3 FPR2 GNAI1 CCR1 GNA13 RGS2	down	**
GO_ADENYLATE_CYCLASE_ACTIVATING_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.0032470	0.0310093	0.4317077	-0.3586868	-1.649688	73	RAMP3 LHCGR ADCY9 GPR65 ADCY4 RAPGEF2 RAMP2 CALCRL ADRA1D TBXA2R RXFP1 ADRB1 ADRB2 PDE4D PTGIR PTGER3 GNAQ GNAI2 PTH1R S1PR4 ADCY2 ADRA1A PTGER4 PTGER2 GPR3	down	*
GO_INTERLEUKIN_1_PRODUCTION	0.0025021	0.0254512	0.4317077	-0.3487184	-1.649561	84	NLRC4 ACP5 IL1B MNDA LPL GAS6 CD36 ANXA1 CARD16 CD33 CLEC7A HSPB1 FOXP1 SIRPA IL10 MEFV CASP1 CCL3 TLR4 CARD8 TYROBP CCR7 MALT1 SUCNR1 SERPINB1 ORM2 MR1 ARRB2 RIPK2 NLRP3 HAVCR2	down	*
MIR545_3P	0.0000016	0.0000565	0.6435518	-0.2885452	-1.649533	329	WEE1 CXCL16 DENND5A OSBPL11 SECISBP2L KCNA2 PRKG2 LYVE1 RDX RCOR1 OTUD1 STXBP6 CAV1 NEDD4L CALCRL BMPR2 PAFAH1B2 NR3C1 CBL MOB1B FAM49A CIT APOD UBR3 PEX5L ADIPOR1 EIF4E TRAF6 CRK SPTBN1 PDE4D TCF7L2 SETD3 TIPARP AGO4 ARRB1 PTAFR RRM2B PRKD3 SCAF4 SNIP1 DPH3 MGAT4A CADM1 NPAS3 NR1D2 DUSP1 RPF1 ELMSAN1 ARL4A ILDR2 PEAK1 CYP26B1 EFR3A CDKN2AIP RBPJ CREBRF KIF13A PSEN1 SEC14L1 SLC14A1 SNX29 USO1 JPH1 TMPRSS11D SHOC2 FOXN2 APBB2 SNX2 ATXN1L PIK3R1 IRF8 FAM43A RC3H1 ENTPD4 ZNRF3 CEBPZ TUBGCP3 CELF2 MAPK8 METTL14 ATAD2B INO80D SYT11 RBL2 FGF2 INTS6 LRP12 MFAP5 ARHGAP18 FBXO30 ARIH1 UBE2D1 PTCH1 G3BP2 CUL3 BCAT1 DOCK10 RNF38 SCAI KIF1B FGFR1 NRP2	down	***
REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES	0.0032838	0.0312907	0.4317077	0.3996575	1.649382	83	CEP72 NEK2 TUBB2B CEP70 PLK1 DCTN2 HAUS5 CEP250 ODF2 SFI1 CDK1 CENPJ FGFR1OP MZT2A MZT2B CEP63 CEP192 TUBG1 NINL TUBB2A TUBA3D TUBA8 CKAP5 TUBG2 CDK5RAP2 HAUS6 HAUS4 CEP152 ALMS1 TUBGCP4 CEP164 TUBA4B NME7 TUBA1C CLASP1 CEP290 DYNC1H1 PLK4 AKAP9 PCNT TUBGCP2	up	*
GO_REGULATION_OF_TUBE_SIZE	0.0012627	0.0152116	0.4550599	-0.3297511	-1.649070	109	SLC6A4 HMOX1 ACE EDNRB P2RY1 CAV1 ADRA1D BMPR2 TBXA2R HMGCR RHOA ATP2B1 PTPRM ADRB1 ADRB2 FOXC2 ROCK2 KCNMA1 PTAFR ROCK1 PER2 P2RY2 KCNMB1 PIK3C2A RAP1GDS1 KCNA5 SLC8A1 HRH1 ADRA1A	down	*
GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_UP	0.0000817	0.0016311	0.5384341	-0.3100527	-1.648544	175	TMEM126A HSD17B11 EGR2 NEDD9 BCL2A1 CD9 ANXA1 PTS ASAH1 ABCG2 LITAF CD93 CRTAM CYP4V2 TMEM38B EPB41L2 AHNAK CASP1 YBX3 ITIH5 NFKB1 ARAP3 FCER1G EVI2A CPT1A ADIPOR2 N4BP1 NUS1 HSDL2 RBPJ PHTF2 CD160 NSMAF GABARAPL2 SNAP23 SH3BP5 KCTD12 ETS1 TYROBP VPS26A GSTO1 EEA1 IRF8 SNX1 AP3B1 TNFRSF9 AGFG1 RHOQ IRF5 TSC22D1 KHDRBS1 PDCD1 CD81 GABARAPL1 ACADL DECR1	down	**
PID_FCER1_PATHWAY	0.0049200	0.0422614	0.4070179	-0.3831589	-1.648539	54	FYN FCER1A S1PR1 CBL NFKB1 FCER1G DUSP1 JUN PIK3R1 GRB2 FOS MAPK8 LAT PAK2 SPHK1 MS4A2 MAPK1 MAP3K1 FER ITK HCLS1 PLD2 SYK PIK3CA PTPN11 LCP2 LYN DOK1 PRKCB	down	*
GO_LEUKOCYTE_MEDIATED_IMMUNITY	0.0000000	0.0000002	0.7749390	-0.2659400	-1.648526	675	SIRPB1 SLPI FOXF1 HMOX1 SWAP70 FCN1 OLR1 ACE SCIMP PECAM1 HVCN1 CD55 GAPT GATA2 IL1B MNDA LTA4H CAT RAB44 EMP2 CLEC12A PTPRB OSCAR CD44 CLEC12B PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 MANBA CD1C VAPA FUCA1 LAMP1 CBL SLC11A1 LILRB3 RFTN1 IL23A CD8A FGR RHOA DNASE1L3 CD36 SLC44A2 CLCF1 DNAJC3 MAN2B1 IGKV2-28 CD33 ARSB ADAM17 ASAH1 RAP1A GM2A ANPEP PTX3 SERPINB9 STOM LAIR1 GATA3 SIRPA IL18R1 TRAF6 CD93 GRN LAMTOR3 CRK CRTAM TFRC RAB14 CD58 CST3 IL10 FABP5 CFD SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D FAM49B CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 CADM1 ITGAX PTPRC SELL HPSE TLR4 ARHGAP9 CD53 PRF1 FCER1G SMAD7 GCA KLRD1 IL7R C4BPB DEGS1 ANXA3 CMTM6 ACTR2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP IGLV2-11 IL6 CD160 CTSS PSEN1 SNAP23 C1QA VAT1 RAB31 HK3 CTSZ RAC2 TYROBP HSPA1B ATP11A RHOG STX7 ENPP4 GLIPR1 GMFG MALT1 SERPINB6 CAP1 TBX21 IGKV3-20 TNFSF13 PSMD12 ALDH3B1 TREX1 CD74 KLRC2 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 TGFB1 AP1G1 DOK3 CD1D ZBTB1 MILR1 SERPINB1 FPR2 TSPAN14 DYNC1LI1 ATP6V0C GPR84 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 ORM2 BRI3 FCGRT PLEKHO2 ADAM10 IST1 IGKV1D-39 COMMD9 UNC13D CCR6 ICAM1 IL18 IL18RAP LAT WDR1 NBN ARRB2 HSP90AA1 NLRP3 HSPA8 HAVCR2 METTL7A CD19 NHLRC3 KIT SIGLEC9 CTSC CD1E ARPC5 KLRK1 LYST SNAP29 P2RX1 PSMD6 IQGAP1 CREG1	down	***
GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN	0.0003172	0.0051078	0.4984931	0.3643691	1.648479	173	EGLN3 CCDC34 DROSHA SORD ANKZF1 CDC6 STC2 SPINT2 APOL2 EXO1 SPAG16 DPY19L2P2 STAP2 FANCA LGMN MPHOSPH9 PKM CHAF1B ORC6 MAD2L1 ETFA REPIN1 BLM GLE1 SKP2 ASF1B PAK1 DTD1 KIF2A MAD2L2 ITPR3 UNC45A CHCHD2 PIAS3 SNRNP25 VBP1 GNPAT SNRPA LMNB2 OSBPL3 MRPL52 TMEM237 GFM2 P4HA1 CENPM FBXO22 ZNF248 MCM5 SIRT5 TMUB1 FARSA LRP11 CCNA2 VDAC1 SHCBP1 UQCRC1 WDR76 VDAC3 GMPR2 PAICS NCAPD3 E2F7 C4orf46 IFI16 CLNS1A TFB1M APEH DRG1 MRPS16 FAM120A TRAFD1 CRAT MTMR4 HDAC3 TIPIN PLEKHJ1 KEAP1 TXN2 NUP37 PFKL RBX1 COA6	up	**
GO_RESPONSE_TO_TRANSFORMING_GROWTH_FACTOR_BETA	0.0000754	0.0015250	0.5384341	-0.3012544	-1.648408	209	SMAD6 ACVRL1 CLEC3B WNT4 CDH5 ENG FOLR1 FYN CAV1 CITED2 NR3C1 TGFBR3 CBL TGFBR2 RHOA PDE2A LTBP4 ADAM17 NLK CAV2 CRK SFRP1 ZEB1 NODAL ROCK2 PRDM16 SDCBP NPNT LIMS1 ROCK1 DAB2 THBS1 CLDN5 SMAD7 VEPH1 HTRA4 MIR17HG TGFB2 NRROS ADAMTSL2 APPL1 JUN LTBP2 FERMT2 SKIL CREB1 FOS UBB RUNX3 TGFB1 PARD6A ZFYVE9 TGFB1I1 LRRC32 MYOCD LTBP1 SMAD2 LDLRAD4 EPB41L5 ARRB2 CDKN1C CREBBP ING2 EDN1 SKI LTBP3	down	**
TCCAGAG_MIR518C	0.0007747	0.0104307	0.4772708	0.3775795	1.647384	126	PCDHGA10 RPGRIP1L PCDHGA9 PCDHGA5 PCDHGA7 SDK2 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 PCDHGA12 PCDHGC5 PCDHGC4 MED12L PCDHGA4 PCDHGB7 PCDHGA3 SALL2 IQCB1 ZNF652 TNK2 DDT PCDHGA2 CHCHD3 RNF44 ZNF606 CSNK1G1 PCDH9 PCDHGB1 TWIST1 NRXN2 DNMT3A RAB15 CLUH GAD1 TCERG1 PATZ1	up	*
GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN	0.0000683	0.0014004	0.5384341	-0.3097892	-1.647306	176	SLC6A4 OLR1 SNX10 HCAR2 PLEKHF2 TXNL1 GTF2E2 USP47 ZEB2 GINM1 ANXA1 SSTR1 PPP1R15B CHMP1B NMUR1 BFAR GPBP1L1 SERPINB9 MCL1 TMEM38B KCNMA1 BNIP2 CDIP1 GCA CPT1A WFS1 PPP2R5A PEF1 CMTM6 KREMEN1 PI4K2A TDRD7 CREBRF WASF2 NKD2 ESD PLEKHA3 MTMR14 SNHG8 SNX2 FBXO11 HOMER1 TSPYL1 GFPT2 TMEM192 BLOC1S6 CACYBP	down	**
GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN	0.0003810	0.0059496	0.4984931	0.3616723	1.647203	180	NEK2 C17orf75 MPP6 PBK KIF18B PIF1 TBRG4 E2F8 ANLN POLE AURKB TYMS UMPS PRC1 GLDC GRB7 NME1 RANBP1 MRPL15 CLHC1 EME1 POLA2 PDCD5 AKAP1 RAD54L KIF11 AIMP2 LIG1 CHEK1 MAD2L1 GNPDA1 PPIL1 INCENP CKS1B RFWD3 CENPH SRCIN1 SDCBP2 ETFB CENPP CCNE1 ALDH7A1 TACC3 KIF22 TRIM37 CASP7 SCN8A MLEC HLA-A PROX1 GEMIN6 HNF1B ASRGL1 NMNAT1 MALSU1 LHPP RAB34 CCNA2 CISD3 BANF1 RFC5 RAD51	up	**
GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP	0.0001120	0.0021237	0.5384341	-0.3111909	-1.646921	172	CD52 SWAP70 ACE CD55 HHEX CYP27A1 LPXN GPR65 LIPA SLC6A12 CD44 LY86 RGS9 CD1C GGA2 SIGLEC6 NDUFAF1 SLC7A7 NAAA MAP3K8 IFI30 HSPB1 MS4A1 TFRC TXN TBC1D9 PTPN21 AHNAK KLF9 STX3 LY96 SELL CCL4 ALOX5AP PLEK EVI2A MATK PKIG PNO1 SNAP23 CD48 SH3BP5 MAP4K4	down	**
PID_CXCR4_PATHWAY	0.0017106	0.0189738	0.4550599	-0.3400003	-1.646916	94	FYN CDC42 FGR RHOA ITGA5 PAG1 CRK RHOB STAT5A FOXO1 UBQLN1 SSH1 PTPRC PIK3R5 GNAI2 HCK PIK3R1 ITGA11 RALB ITGA9 GNAI1 GNA13 ARRB2 CXCR4 VPS4B CD3G PTEN ITCH MAPKAP1 ITGB1 PIK3CG HLA-DRB1 CD3E ITGA6 PLCB2 CD4 PIK3R3 ITGA10 CD3D GNG2 BLK PIK3R6 JAK2 ITGA1 RGS1 PRKCZ STAT3 PIK3CA PTPN11 STAT1 LYN	down	*
GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN	0.0003109	0.0050325	0.4984931	0.3648660	1.646726	166	MMP13 FOXM1 HELLS MCM10 NUP107 MND1 AGFG2 IQGAP3 EBF3 PTTG1 CUEDC1 RAD54B TYMS DLGAP1 WDR90 TNC LDHB RUVBL2 NOS1AP EXO1 ZFYVE27 AGT MCM7 ABCC5 RAD51AP1 PIH1D1 PKMYT1 BRIP1 RAD18 BLM ZCRB1 CKS1B LRRC6 FAT1 E2F1 EZH2 SEMA4F MOV10 INTS7 CEP192 DCAKD LMNB2 TRIM37 SUDS3 COPS7B GINS2 POLD1 CCT7 SH2B1 CENPT SNX11 TMUB1 CDH11 CEP152 DTNB ARRDC1 TNKS1BP1	up	**
GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN	0.0005214	0.0076123	0.4772708	0.3661308	1.646667	161	LINC00342 CABIN1 MSTO1 PTTG1 SPATS2 GLDC GON4L LIME1 COQ3 LDHB P4HTM GTPBP3 IGLV1-44 MCM7 MPHOSPH9 FANCD2 CHD6 ORC6 ADCY10P1 COX19 TMEM63A AKT2 SYMPK ETV7 DDX51 VN1R1 TNFRSF25 PKD1P1 IGHG1 PAXIP1-AS1 PDK1 C16orf71 METTL3 HMGXB3 FGFR1OP ZNF500 GRAMD1A PABPC1L IGLV6-57 SPG7 MSI2 HECTD1 ITFG2 ENOSF1 DENND5B FAM71E1 DGKA SRSF1 STMN3 PDIA4 ZNF274 AMN1 GABPB1-AS1 GTF3C2 CDK5RAP1 SNRNP70 SNRNP200 TCF3 IGLV3-19	up	**
GO_CD4_POSITIVE_ALPHA_BETA_T_CELL_DIFFERENTIATION	0.0027171	0.0269529	0.4317077	-0.3635578	-1.646542	67	SPN IL23A ANXA1 FOXP1 HLX GATA3 IL18R1 FUT7 SOCS5 SMAD7 NCKAP1L CD80 IL6 PTGER4 CD83 GPR183 MALT1 RC3H1 TBX21 RUNX3 CD86 IL18 SEMA4A RIPK2 NLRP3	down	*
MATTIOLI_MGUS_VS_PCL	0.0040485	0.0365261	0.4070179	0.3893869	1.645898	96	IGHV4-61 RUVBL1 HBA1 TBRG4 IGKV4-1 MCM4 MCM2 IGKV2D-28 IGLV3-10 AKAP1 PSMD4 CAD PARP1 CKS1B NUSAP1 EXOSC2 AP3D1 CCT3 IGHG1 FADD PSMC4 LAPTM4B INTS7 SAP30 RRP9 MCM6 KIF21B LPCAT4 MCM5 SRSF1 NUP62 SMARCA4 TBCB IGLV3-19 SEPHS1 PAICS ENO1 NUP210	up	*
BILD_HRAS_ONCOGENIC_SIGNATURE	0.0000346	0.0007951	0.5573322	-0.3011938	-1.645454	216	CXCL3 EREG IL1A CD55 TBX3 IL1B LRRC8C PTPRE MBOAT2 LRRFIP1 BMP2 FOSL1 MYD88 DENND2C TRIB1 IER2 CCNL1 ATP2B1 CLCF1 B3GNT5 HBEGF PLXNA2 KLF6 MALL PTX3 TOR1AIP1 ADRB2 TCF7L2 MCL1 PDGFA ITPRIP CASP1 PLAUR MAP1LC3B CXCL2 HPSE DUSP1 ELK3 OXSR1 CALM2 TGFB2 PIAS1 PNMA2 DDX17 JUNB PPP1R15A ELOVL7 PNPLA8 CXCL5 TNFRSF10B PALMD FOS SPRY4 EHD1 SERPINB1 TSC22D1 DUSP5 PIM1 ADAMTS15 CCL20 GLTP	down	***
CAGTGTT_MIR141_MIR200A	0.0000086	0.0002455	0.5933255	-0.2951987	-1.645255	263	SEMA6A DLC1 OSBPL11 TRHDE SIK1 QKI ELF2 PAFAH1B2 YPEL5 CBL ZEB2 RBM7 PPP1R15B C1orf21 FOXP1 TTYH2 PPP2R2A LHX6 TFRC ATP6V1B2 KIF1C STAT5A DUSP3 RNFT1 ZCCHC24 ARNTL MYRIP SPAG9 RBMS1 FRMD4A KIAA0408 CYP26B1 KPNA3 BACE1 IKZF5 SIAH1 TGFB2 FOXN3 MTPN CREBRF SLC25A3 PPP2CA PSEN1 JUN STAT4 RABGAP1 APBB2 DDX5 KLHL18 GRB2 PDZD2 CDK17 PTP4A1 YTHDF3 TSHZ3 TTBK2 STRN PDS5B YTHDF2 ATP6V1A IRS2 ATXN1 CLASP2 GATA6 PHLPP2 MBNL1 INO80D MOB3B YAF2 DIXDC1 EPHA2 GRIN3A MBD5 CUL3 ARPC5 CAMSAP2 NRP2 C2orf42 SFPQ WDFY3 YTHDC1 ARHGEF18 KALRN PLAG1 CHP1 CDC14A HIPK1 FUS MYH10 DCUN1D3 CDC42BPB ATP1B1 CSNK1G3 UBE3A MTSS1 DR1 SLC23A2 WDR26 CSF3	down	***
GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP	0.0005455	0.0078881	0.4772708	0.3625276	1.644997	176	FOXM1 HELLS CDC45 MCM10 BUB1B DNAJC12 CENPF POLQ PBK BRCA1 PHGDH E2F8 HILPDA AURKB ECT2 ESPL1 CDC6 SFXN1 TRIB3 CDC25A COCH CCNF DTL ZWINT MYL6B COQ3 TNC KIF23 AURKA THBS4 WDHD1 GPSM2 CHEK1 MAD2L1 DLG5 CBX5 MCTP2 DNA2 SPAG5 DLGAP5 SCLY TRADD KIF22 GINS2 FHL2 ELAC2 IP6K2 PPCDC NOC4L SUOX MARCKS CCNA2 SHCBP1 RAD51 TPGS2 SUPT3H NME7 SMC2 COPZ2 GPN1 RASGRP1	up	**
WINTER_HYPOXIA_UP	0.0039507	0.0359221	0.4070179	0.3950421	1.644623	87	CA9 AK4 SLC2A1 HILPDA ANLN GAPDH CA12 XPO5 NME1 RUVBL2 IGF2BP2 TPBG PTGFRN ALDOA MNAT1 TPD52L2 RHOC MRGBP GSS PLEKHG3 METTL22 PSMD2 TMEM30B P4HA1 TNS4 PFKFB4 MRPL14 NTMT1 BMS1 PGAM1	up	*
HALLMARK_IL6_JAK_STAT3_SIGNALING	0.0035248	0.0330829	0.4317077	-0.3575525	-1.644471	73	CXCL3 ACVRL1 IL17RB HMOX1 IL1B CD44 MYD88 CD9 CBL CD36 MAP3K8 IL18R1 PIK3R5 IL6 SOCS3 JUN IFNGR1 GRB2 TGFB1 IFNAR1 PIM1 CCR1	down	*
CCAWWNAAGG_SRF_Q4	0.0051764	0.0439623	0.4070179	-0.3657199	-1.644343	64	EGR2 CORO1C KCNK3 CSRP1 PICALM KLF6 NR4A1 TNNC1 THBS1 ACTG2 MYH11 MRVI1 SRF PODN RASSF2 FOSB TCF4 DUSP5 MRGPRF TAGLN MBNL1 PDLIM5 DIXDC1 PTCH1 ACTB EGR1 CFL2 SVIL PLN DUSP2 SREK1 NKX2-1 MYLK	down	*
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_DN	0.0008904	0.0116221	0.4772708	0.3718094	1.644312	141	SYT8 GRIK2 FOXA3 CUZD1 KCNK5 GABRB3 FAT2 GPR35 BAIAP2L1 C4orf19 ARHGAP33 MARVELD3 DZANK1 MYL6B SHC2 RSPH1 CYP24A1 TIMD4 MSX1 TRPV6 SDK1 TOM1L1 OAZ3 HHIPL1 GEMIN7 SPAG8 RECQL5 NRTN C2CD4C SPATA6L DNAH6 C16orf71 ANKRD55 ATP7B HIRA PAPLN ZNF239 KIF21A HIP1R MAP6D1 ACSL6 DHTKD1 CADM3 HPD	up	*
BOQUEST_STEM_CELL_CULTURED_VS_FRESH_UP	0.0000008	0.0000328	0.6594444	-0.2822931	-1.643906	375	SEMA3G CXCL3 HSPB7 TMEM100 CLIC3 EDNRB PPARG CLEC3B EMP2 GREM2 CYP4B1 BMP2 ENG LPL CD44 SAMHD1 SRSF7 TGFBR3 CD9 TRIB1 SYNC CCNL1 TXNIP KCNAB1 LTBP4 HBEGF OLFML2A EIF1 BTG2 EIF5 MAP3K8 PRELP KLF6 GLS SLC7A11 SPTBN1 SPRY2 CLK1 CES1 SRGN APOC1 RHOB PER3 SYNPO FOXO1 SORBS1 KLF4 AOC3 PEG3 RUNX1T1 FMO2 KLF9 KLF11 THBS1 BCHE PLBD1 NPR3 ABCC4 CCL3 PER2 CXCL2 ATF3 CD302 DUSP1 INHBA N4BP2L1 MATN2 RAP1GDS1 CYP26B1 TP53BP2 RASL12 ARHGDIB TGFB2 RPS6KA2 PDK4 MYLIP CTSS NEK7 OASL JUN MITF HSPA1B JUNB RABGAP1 PPP1R15A PODXL GLIPR1 PIK3R1 ACKR3 CD83 SELENBP1 PTGER2 MFAP4 REL GPRC5A CELF2 CD34 PELI1 FLNC EPHA3 FAXDC2 COL15A1 SOD2 RGS2 ADAM10 ABI3BP CLEC2B ETS2 JUND GEM GPX3 FGF2 PDLIM5 CPQ SLC31A1 TFPI IER5 CDC42EP3 CDKN1C ACACB MT1M RND1 METTL7A LIMCH1 NFKBIA	down	***
FARMER_BREAST_CANCER_BASAL_VS_LULMINAL	0.0000286	0.0006758	0.5756103	0.3460079	1.643779	278	BBOX1 FOXM1 HS3ST1 MCM10 GABRP TFAP2A GALNT6 UGT8 DNAJC12 MPP6 PKP1 NDC80 TTC39A PHGDH SPDEF TFF3 IRS1 TTK PRR15L KIF14 GMPS STIL KRT16 CENPA PTTG1 TPX2 E2F3 AGR2 CA12 GALNT10 SRPK1 LDHB TTLL4 MELK BBS1 TRIM29 IGF2BP2 BUB1 TPBG MYO10 HHAT SLC2A10 P4HTM CPD RNF43 AMACR TOM1L1 MCCC2 YEATS2 SIDT1 SLC9A3R1 HEBP2 CHEK1 ACTL6A PFKP RAD51AP1 INPP4B SKP2 NRTN EFCAB11 KRT18	up	***
GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_DN	0.0001215	0.0022724	0.5384341	-0.3105933	-1.643759	172	OLR1 TMEM170B WDR74 AQP9 IL1RN OTUD4 EPB41L3 MOB1B RFTN1 RBM7 NFIX TRA2B CLN5 TCF7L2 MTHFR FOXC2 PTPN12 PPM1K TJP1 SOCS2 PER2 CDKN1A GPR85 CCND2 WFS1 UNC5A BACE1 RSRC2 PIAS1 PHTF2 APPL1 SRSF3 MITF ETS1 ELP5 FOXN2 TBC1D12 SKIL ZCCHC9 TMEM128 GPRIN3 PDS5B CD86 C16orf72 STK40 MICU3 PGGT1B PTCH1 RND1 NRP2 ZFPM2 MT2A ATF4 DNAJA2 PPP1CB CSF2 PSIP1	down	**
GO_CYTOPLASMIC_REGION	0.0001966	0.0033897	0.5188481	0.3558755	1.643757	202	KIF1A GRIK2 DNAH2 RPGRIP1L AP3B2 CENPF UCHL1 SPAG17 ANLN PCLO DNAH3 AK8 DNAI1 ARMC4 BBS1 SPAG16 KIF3B HYDIN WDR78 CCDC114 DCDC2 GPSM2 BLOC1S1 WDR66 DNAH8 IFT172 GAS8 DNAH11 TULP3 CCDC40 DRC1 KIF5A AP3D1 ERC2 KIF19 SPAG6 SAPCD2 LCA5 MYO5B DNAH5 RANGAP1 SPEF1 BBS5 SPG7 DNAH7 MNS1 CCDC151 HIP1R CLTA TRAF3IP1 CLTB DNAJB13 WDR34 TTLL3 EFHC1 AP3M2 RPGRIP1 BSN DNAI2 WDR35 DYNC2H1 NEK4 RSPH4A TCHP SYBU DNAH1 PPFIA3 TRAK1 WLS MAPK8IP3 DTNBP1 TTC30B RIMS1 ENO1 CLASP1 DNAAF1 DYNC1H1 MAK GLI3 WDR63	up	**
chr3p23	0.0042429	0.0378805	0.4070179	0.8747665	1.643717	4	ZNF587P1 ZNF860 OSBPL10-AS1	up	*
GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN	0.0003889	0.0060463	0.4984931	0.3632127	1.643247	173	HJURP FAM81A RUVBL1 GMDS FBXW8 CDK4 SPP1 EIF2B5 PMS2 EIF3B SHMT2 SIMC1 TMEM41A NUDT1 MKI67 F2RL1 WDR3 POC1A TRRAP PASK FANCD2 SLC12A7 GLE1 PPP1R37 GPX8 CKS1B C1orf112 ACP6 SCTR KIAA1211L ATAD3A KCTD1 DAP TELO2 TACC3 LONP1 OSBPL3 PTGES2 SSRP1 MLEC FHL2 ELAC2 GTF3C1 DGKA ACLY MCM6 WDR83 LTV1 HMCES SKAP1 TXNL4B NME7 SMPD4 MON2 GPX7 SYNE2 ANKRD46 NELFA CNPY4 EIF2D POLRMT RANBP10 ZNF598 HINT1 MEX3D SNHG17 NHP2 RCC2 WDR89 TXN2 PPP2R1A NBAS EBNA1BP2 CTPS1 PRRC2B MIEF1 MPLKIP	up	**
GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN	0.0000530	0.0011344	0.5573322	-0.3113842	-1.642922	171	SLPI ARHGAP31 IL1A CXCL16 FBP1 LONRF1 FLVCR2 BCL2A1 IL1RN SCARF1 HPS5 ZEB2 HSPE1 EIF4A1 RRAGC B3GNT5 MCTP1 ADAM17 MTF1 STOM TXN LIMS1 PLAUR ATP6V1D UBQLN1 DPH3 CD53 PRF1 PROCR KLRB1 GABARAPL2 PHACTR2 PSMA1 STAT4 GIMAP2 GSTO1 WTAP PI4K2B ATP13A3 RRN3 PIK3AP1 DDX18 AZIN1 PDE12 LRRC32 SOD2 KYNU ETS2 PITPNA MOB3B HSP90AA1 SRSF10 NFKBIA CD1E FNIP2 SMPD1 SLFN11 SPHK1 MB21D2 C1QB CLEC4E COX20 CALR FPR3 CCDC93 SERP1 IRF1	down	**
GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0006062	0.0086197	0.4772708	0.3716354	1.642872	143	SPATA24 MCM10 NEK2 IQCE PBK THOC3 IFT122 KIF14 CDC6 UHRF1 ARHGAP33 FERMT1 MKI67 TSGA10 CCDC77 MPO TGM1 PPP5C FADS2 SYMPK BTBD2 PARP1 PES1 TMED3 ASF1B HDGF EXOSC2 RAPGEFL1 IGSF3 CBX1 CHST3 NMRAL1 SSRP1 HECTD1 SLC22A23 SEC14L2 EPN1 CENPV GID8 TMEM147 ZRANB3 RFC5 CARHSP1 PPP6R2 TAB1 TARBP1 CPOX UQCRQ SIRT6 ADCY6 TMEM256 SNRPC UBTF ZFPM1 SLC40A1 TUBGCP2 STARD10 GLRX5 ABCD3 CS PPA1 COX6A1 RAB3IL1 EXOSC7 BUB3 EDC3 GATM CLPB	up	**
GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN	0.0000962	0.0018697	0.5384341	-0.3070434	-1.642622	187	WEE1 RAB11FIP1 OSBPL11 GPR65 RAPGEF2 CLDND1 TGFBR3 TRIB1 ANXA1 UBL3 ENTPD1 PICALM TTYH2 STOM AKT3 SRGN CD58 EVI2B AHNAK LIMS1 ARNTL VRK2 SPAG9 ITPK1 COTL1 PAPSS1 FXYD7 SLC6A6 DEGS1 KLRB1 PHACTR2 AQP3 RAPGEF1 GPR183 TAGLN2 TIGIT GPRIN3 CD74 AKIRIN2 PEA15 DUSP5 ATXN1 TERF2IP LGALS3 CCR6 CDC42EP3 EPHA4 ARHGAP18 S100A4 CTSC KIF1B RORA NABP1 IQGAP1 EMC3 EHD4 RSU1 PIEZO1 HERPUD1 SPSB1 SPPL2A SH3BGRL3 ITGB1 SH3GLB1 FAM53B HLA-DRB1 RNF214 ATP2B4 MAP3K1 NCOA7 RNF19B MYO1F MYO5A CBLL1 ADAM19	down	**
REACTOME_APC_C_MEDIATED_DEGRADATION_OF_CELL_CYCLE_PROTEINS	0.0037085	0.0342795	0.4317077	0.4007698	1.642506	79	BUB1B NEK2 CCNB1 PLK1 AURKB PTTG1 BTRC AURKA MAD2L1 PSMD4 SKP2 ANAPC5 CDK1 PSMB5 ANAPC7 PSMC4 CDC23 PSMA5 PSME2 FZR1 ANAPC1 PSMD2 PSMB3 CDC20 PSMB4 CCNA2 ANAPC2	up	*
GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP	0.0007014	0.0096530	0.4772708	0.3616026	1.641974	177	KIF20A HJURP CDC45 FANCI CCNB1 NDC80 RACGAP1 E2F8 SPP1 ALDH18A1 GPI TPX2 CCNB2 MCM2 CDC25A ZWINT RANBP1 CEP55 MKI67 PCCB SLC22A18AS GPSM2 DNAJC9 DET1 COQ9 PARP1 NCAPG2 NUSAP1 ATIC NCAPG MRPS12 PSMC4 VBP1 ILF2 DPP3 TUBG1 AARSD1 TUBB2A PSME2 TUBA3D ROGDI TK1 CLTA MAGOHB PEX10 TSTA3 ACLY MCM5 AATF NT5DC2 PRIM1 HK2 TTC1 SEC13 COX5B PGAM1 UQCRQ SPR NMT1 PAICS UBE2C COX17 APOBEC3B APEH LASP1 PSTPIP1 FBXO5 ABHD2 BAK1 TMPO GTF2F1 COX6A1 EIF4G3 P2RY6 COPS7A IPO4 PSMD8 DEF6 ACOT7 COX6C P4HA2 WDR12	up	**
GSE6259_BCELL_VS_CD8_TCELL_DN	0.0000538	0.0011472	0.5573322	-0.3111577	-1.641727	171	AKAP5 MS4A7 TAL1 RAPGEF2 PTPRE LONRF1 IDI1 CIR1 YPEL5 FRAT1 ERG TNIP3 PICALM NLK FZD4 TFEC MYCT1 PPM1K YBX3 ST3GAL2 NR1D2 HES1 AFF1 TANC1 MAPRE2 FAM102B NRROS BTG1 CREBRF HECA GAS2L1 CARD8 IFNGR1 PNPLA8 MBNL2 HERC1 RHOQ YPEL2 IRS2 HBP1 TAGAP MEIS1 PHLPP2 BMP2K IER5 CEBPD CXCR4 FBXO25 NUP98 METTL7A NPAT STK4 FDFT1 GRB10 ZBTB44 PSIP1 DUSP6 CCDC112 SLC38A2 FAM8A1 KIAA2026 PIK3CG	down	**
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP	0.0026279	0.0262803	0.4317077	-0.3248233	-1.641501	113	SLPI CD52 TSPAN4 MNDA SNX10 LPL SAMHD1 BCL2A1 LILRB3 BTG2 LITAF SIRPA GRN MSR1 MPEG1 CASP1 STX3 LAPTM5 MARVELD1 PTPRC CXCL2 CD53 HLA-DQA1 HCK PROCR CTSS C1QA TYROBP CD7 RRAS CD74 CHIA LGALS3 ORM2 CCR1 SELPLG GLTP GPX3 MS4A4A S100A4 CTSC NABP1 IQGAP1 LYZ CYBA C1QB S100A8 FPR1 MT1E QSOX1	down	*
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14	0.0011900	0.0145539	0.4550599	0.3770934	1.641438	124	CDK4 EIF2B5 TYMS NME1 RANBP1 CLPTM1L CISD1 YKT6 SMYD2 NSUN2 PKM SEC61A1 FBL DCTPP1 PES1 THOP1 CCT3 PSMB5 GNPNAT1 GOLGA5 UQCC2 EFTUD2 SLAIN1 UBFD1 DVL3 DTYMK MLEC TCEA1 SND1 PSMB3 PRMT1 TMEM147 SRSF1 PDIA4 TCERG1 RAB34 SMARCA4 HDLBP BANF1 SEC13 ERGIC1 TBCB RPN1 EIF4G1 APEX1 PTOV1 MRPL20 PIGQ PPP1R14B DDX41 PRRC1 MRPL12 GGA1 ASL NHP2 TMEM167A CS PPA1 FGF1 EBNA1BP2 IPO4 DNAJC2 PTP4A3 RCN1	up	*
GO_NEGATIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS	0.0000009	0.0000351	0.6594444	-0.2841315	-1.640531	367	GPR17 CD300LF FOXF1 HMOX1 TAL1 KLF13 PPARG ADTRP CD55 GATA2 SPN MNDA LPXN SAMHD1 CLEC12B PRKAR1A IL1RL1 OTUD4 CD22 TRIB1 LILRB3 FGR APOD ANXA1 MIR146A FBXO7 ADA RNF125 HLX PAG1 SERPINB9 NFE2L2 GRN CRK SFRP1 IL10 NRARP DUSP3 THBS1 SOCS5 LY96 UBQLN1 CCL3 PTPRC AXL ID2 TLR4 MIR24-2 SFTPD FCER1G DUSP1 SMAD7 INHBA IL7R UBASH3B HES1 C4BPB TGFB2 GNRH1 IL17D CD80 ELF1 CD160 APPL1 SEC14L1 PSMA1 LRCH1 NOTCH1 GABPA CUL4A PDE5A TYROBP PTGER4 PIK3R1 RC3H1 FSTL3 TBX21 CST7 TIGIT PELI1 YTHDF3 RUNX3 TREX1 CD74 CR1 SMPDL3B TGFB1 MILR1 YTHDF2 NLRP6 LRRC32 MIA3 CD86 CNOT7 PDCD1 LGALS3 MEIS1 KLRC4-KLRK1 N4BP2L2 GPR18	down	***
GO_POSITIVE_REGULATION_OF_CELL_ACTIVATION	0.0000076	0.0002200	0.6105269	-0.2927877	-1.640214	294	SIRPB1 CD55 GATA2 IL1B FYN CAV1 FGF10 CDC42 IL1RL1 GAS6 LAMP1 TGFBR2 IL23A FGR RHOA ANXA1 CLCF1 CD5 ADA CLEC7A MAP3K8 HLX GATA3 SIRPA TRAF6 WNT3A TFRC ZMIZ1 IL10 BST1 PTAFR THBS1 CEBPA CLECL1 SOCS5 MPL FAM49B CCL3 CDKN1A PTPRC SELP AXL TLR4 IGFBP2 FCER1G PLEK IL7R HES1 NCKAP1L CD80 IL6 CD160 TYROBP CCR7 PIK3R1 CD83 GRB2 GPR183 MALT1 RPS6KA1 DOCK8 AP3B1 TBX21 PELI1 TNFSF13 RUNX3 CD74 TGFB1 VAV3 AP1G1 CD1D ZBTB1 CD6 CD86 IRS2 PDCD1 CD81 KLRC4-KLRK1 IGHV3-23	down	***
GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN	0.0000806	0.0016131	0.5384341	-0.3083751	-1.639787	176	SNX10 HSD17B11 DDX6 INPP5A DYRK1A BCL2A1 CD9 CD22 SPG21 RANBP9 MS4A1 IL18R1 CYP4V2 MCL1 EPB41L2 AHNAK CASP1 ITM2B RRM2B ATP6V1D SELL M6PR EPS15 DUSP1 PPP2R5A VAMP5 IL7R HLA-DQA1 NXF1 ETS1 ATP11A SNX2 CCR7 CD83 ENTPD4 RASSF2 RRN3 CD6 SBF2 RELL1 TOB1 PPID PDE4B CCR6 GLTP RNF138 WDR1 TPT1 SLC25A20 ARIH1 CREBBP CD19 ARPC5 SKI DNAJB9 IL16 EIF4A2 SMAD4 DNAJA2 EIF4G2 CTSH ITGB1 ZFP36 AKAP12 MATR3 SKAP2 ITGA6 RNGTT CFLAR PKD1 TTC39B CD4 ANKH MFHAS1 IL10RA CYTIP RCAN3 TMEM71 CD47 FASLG B2M LUC7L	down	**
MODULE_180	0.0020885	0.0221906	0.4317077	0.3822711	1.639664	110	MNX1 TSPAN8 PRLR BDH1 PRR15L AKR1C1 AGR2 SPINT2 GRB7 SYT12 TJP3 MAP7 SYTL2 FOXA1 MSX2 ICA1 HOOK1 MDK SLC9A3R1 B3GNT3 MSI1 LRRC37A4P KRT18 LRRC4 ARHGEF16 LLGL2 MSI2 MMP7 KRT19 ERBB3 UBXN6 KRT8 ANXA9 SSH3 ANK3 EPCAM CDH1 BLVRB	up	*
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIGRATION	0.0019425	0.0209834	0.4550599	-0.3402498	-1.639477	93	PECAM1 CDH5 ESAM CDC42 NCF2 RHOA RAPGEF4 RAP1A JAM3 ROCK2 ROCK1 VASP CLDN5 JAM2 PIK3R5 GNAI2 RAC2 PIK3R1 PLCG2 PRKCG MYL12A VAV3 GNAI1 ACTN2 ICAM1 CXCR4 ACTB RAPGEF3 CYBA ITGAL ITGB1 NCF1 PIK3CG	down	*
GO_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING	0.0045204	0.0396937	0.4070179	-0.3638208	-1.639348	68	PPARG TBX3 EGR2 LMO2 LDB2 MEF2A TBX2 RB1 NFE2L2 SETD3 EXOSC9 PRDM16 TBX4 TAF9 TBX5 WFS1 JUN GABPA CREB1 TBX21 FOS SMAD2 RBL2 CREBBP SIN3A BHLHE41 ATF2 ATOH8 EP300 MEF2D	down	*
GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_UP	0.0002464	0.0041020	0.4984931	-0.3149494	-1.638890	159	SLC31A2 EREG PID1 FYN MS4A15 MARCO BCL2A1 SLC11A1 MCTP1 SIRPB2 ASAH1 AHRR NFE2L2 BTG3 TCF7L2 TMEM38B FBXL5 LIMS1 BST1 PLAUR DAB2 STX3 ARAP3 ALOX5AP EVI2A PINK1 FKBP15 IL24 KREMEN1 PROCR HCAR3 DDX60L VPS37A NSMAF PDCD6IP ARL5B SH3BP5 CCDC50 TMEM251 GSTO1 PNPLA8 NDST1 TINF2 SNX9 RUNX3 MYL12A ZFAND6 VAV3 TSC22D1 IRS2 BRI3 LTBP1 CCL20 BNIP3L ATP9B ING2 BCAT1 RET B3GNT2 MROH6 IL16	down	**
GO_POSITIVE_REGULATION_OF_ADAPTIVE_IMMUNE_RESPONSE	0.0022738	0.0236166	0.4317077	-0.3458791	-1.638432	83	IL1B CD1C SLC11A1 IL23A ANXA1 CLCF1 ADA HLX GATA3 IL18R1 TRAF6 TFRC SOCS5 FAM49B PTPRC FCER1G CD80 IL6 STX7 MALT1 TBX21 TNFSF13 TGFB1 CD1D ZBTB1 CD81 FCGRT IL18 RIPK2 NLRP3 CD1E	down	*
DODD_NASOPHARYNGEAL_CARCINOMA_UP	0.0000000	0.0000000	0.9653278	0.3182927	1.638182	1384	ATP10B CCNO SAA1 RHPN2 LTF ATP6V0A4 ALDH3B2 PRR15 RIBC2 KCNMB2 B3GALT5 SCIN ABCA13 MUC13 MYEOV ABCC2 PTPRT SLC16A9 FUT6 HHLA2 SPATA24 MYCBPAP FOXA3 ADH1C EYA1 GALNT14 OR7E14P FAM182B WFDC3 DNAH2 GMDS BDH1 GPT2 GABRP EPN3 SLC13A3 CECR7 CP CHST6 C5orf63 ANKFN1 SYNPR-AS1 PROM1 LRRC43 PPIP5K1 ADRA2A TRNP1 ARMC3 PTPRN2 MUC4 FUT3 WFDC2 FAM153A CIB2 C21orf58 TSHZ2 GCNT3 TOX3 MUC16 TTC25 GUCY2C MKS1 PLEKHA6 PLEKHH1 CCDC113 SPDEF TFF3 FANK1 PTPRH CCDC74A LCN2 MUC5AC AGFG2 ASIC1 SMPD3 PRR15L ALDH1L1 BCL2L15 SLC27A2 RHOV GALNT4 DAW1 SPAG17 FA2H COL28A1 FCER2 BCAS1 LYPD6B TTC26 SIX1 ACOT8 SAMD15 VSTM2L H19 C4orf19 KCNT1 AGR2 RAB36 GRHL3 DNAH3 CA12 CD163L1 PLS1 CIB1 MUC20 CCDC74B ASXL3 VILL C2orf81 DZANK1 LRRC27 PLEKHS1 EPS8L1 DNAI1 C6orf132 TJP3 MANSC1 RSPH1 ARMC4 SDR16C5 ANKUB1 STAG3 OSBPL2 SYTL2 C9orf116 SPAG16 SMAGP FOXJ1 TRIM29 TSGA10 FBXW9 MAP3K13 CCDC13 RPL32P3 BPIFB1 TMEM184A IQCD PSENEN REC8 SLC2A10 SYNE4 P4HTM GPR182 ODF2 KLHDC7A IFT43 C6 HYDIN AGBL4 WDR78 TPCN1 TTC22 SPEF2 TEKT2 IL20RB FAM216B EFCAB12 SRGAP3-AS2 CCDC89 CCDC114 DCDC2 BEST4 ANKMY1 C7orf57 WDR66 TGM1 AP1M2 C11orf16 NME5 RIPK4 SLC9A3R1 B3GNT3 CCDC148 NEK11 PDZK1IP1 ASS1 IFT172 STEAP4 GAS8 CBY1 CCL28 MSI1 DNAAF3 OXTR BACE2 SPATA17 CAPS DNAH11 FBXL8 SPAG8 CCDC136 KLHL3 FUT2 CCDC170 C4orf47 MGLL WWC1 CCDC40 OSBPL7 RECQL5 PTPN3 TXLNB GPX8 CCDC78 IKBKB FGGY PRRT3 TTC9 DRC1 FRMPD2 MB KIAA0556 DNER LRGUK LRRC6 DMKN FAM221A CROCC SPATA6L DNAH6 EFCAB6 ARHGAP39 CLMN KCNE3 SERTAD4 TNFRSF21 DIDO1 MDH1B SSUH2 TTLL9 WDR54 ANKRD54 SUN1 STX18 GIPR FAM81B IGHG1 REEP6 TMEM8B LRRC4 KIF19 WDR31 SPAG6 TCTN2 TRIM41 SDCBP2 KLHDC9 NEK5 CCDC88C EFCAB1 TTC6 TTC23L TRIM7 NF1 RAET1E RALGPS1 TNRC18 KIAA1211L LCA5 MYO5B AK7 TTC16 DNAH5 LRRC56 PRKAA2 CXCL17 FAM102A TMEM231 CASC1 TSPAN1 PPP1R36 FOCAD FAM86C1 C3orf67 ANKRD45 PIAS3 SNHG18 DENND6B KIAA1257 SPEF1 CAPS2 ST14 CYP2C8 NPHP1 COL1A1 NEK10 GDPD3 SPG7 SLC26A2 DNAH7 SPATA18 TSNAXIP1 EFCAB2 MNS1 C22orf15 LLGL2 ARHGAP32 CCDC151 TUBB2A FAM166B GPRC5C TPO IQCG RGS22 FBXO15 MORN2 C9orf152 PPOX CADM4 SLC13A4 CASP7 CNGA4 KIF21A PINLYP MSI2 MROH9 S100A9 CCDC146 TUBBP5 ATG9B HECTD1 PCDH9 GRIN3B USP43 SPAG1 TEKT3 IGHM LRWD1 SRD5A3 SPA17 PLAC4 SMIM22 SGSM3 FHL2 AHNAK2 EPB41L4B SLC9C2 IQCH TTLL10 THRB TRAF3IP1 TMEM232 DNAJB13 PROCA1 TMEM234 C15orf62 KCNB1 AGBL2 IQUB LINC00467 CCDC30 KLHL32 EFHC1 TCTN1 RSPH10B CATSPER2 CXCL1 PPP6R1 ENTPD3 ASRGL1 UPK1B ODF2L CDRT1 EML6 FAM174A LPCAT4 ODF3B VWA3B ANXA9 DNAI2 SPINK5 IGHA1 LRRC73 SMIM6 IFITM10 DYNC2H1 ZNF599 CHRNA3 FBXO36 MMP24 EDAR EFHB KATNB1 YIPF2 CH25H TMEM254 RSPH4A SLC41A3 VWA3A LRRC46 TMEM45B CCDC60 MVP STRBP GNAL CEACAM5 MICAL3 B9D1 CES4A LRP11 C19orf33 ULK4 DZIP3 TTC12 TMC5 ZNF445 RTEL1 TMEM72 SYBU CEP164 PCSK5 CCDC181 CLUAP1 DNAH1 OSBPL10 TUBA4B DLEC1 PRSS22 MAP3K9 R3HDM4 SLC25A29 CHMP1A MCU LRRC71 EYA4 ENKUR ERGIC1 RDH10 TCTEX1D1 TRAK1 WDR49 VPS9D1 GNA14 LRG1 WLS FAM83E ERBB2 TTC39C ENPP5 CASC2 ALDH3A1 RAB43 BCL6 LOXL4 GNE MAP1LC3A CMTM8 CGN CHL1 ZNF204P DHRS3 UBXN10 KIAA1522 BCAN NEIL1 GOLGA2 ALOX15 TMEM256 FBXO34 ADARB2 NSUN7 CYSTM1 DCDC1 CAPN9 KRT80 UBTF CLDN10 RIPK3 RORC FOLH1 ZMYND10 DHRS9 LXN TAX1BP1 ZER1 MUC1 PLIN3 STK11IP TK2 B3GNT4 TTLL5 GSDMC PLXNB1 APOBEC4 MOK HEMK1 MAP3K19 PPP1R16A KCNK6 TMCO6 NQO1 SPATA33 DNAL4 ZSWIM5 STK33 ACSBG1 PLAC8 KCNJ15 ARMC2 KLK10 MORN3 MED16 DNAAF1 WDR55 ZDHHC1 DYNC1H1 MAK SCRN2 TEKT1 ZDHHC13 ABLIM3 PPP1R13L REXO1 WDR63 SIGIRR CRAT RBM20 MST1 ST6GALNAC1 CNKSR1 NOXA1 PEX11A CAMK2G	up	***
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP	0.0000157	0.0004096	0.5756103	0.3406769	1.637276	327	KIF12 PRLR ONECUT2 ZDHHC8P1 EPN3 DEPTOR GALNT6 ZNF84 ZNF12 IQCE PRRT2 TTC39A PLEKHH1 SPDEF TFF3 CREB3L4 BCAS1 POLE C4orf19 AGR2 CA12 EIF3B AVL9 ASTN2 SLC4A8 EPS8L1 TJP3 RSPH1 ZNF74 FOXA1 FRS2 TMEM184A SLC2A10 SYNE4 P4HTM SYCP2 SFI1 ICA1 SBK1 MCCC2 SIDT1 SLC9A3R1 KDELR2 CSRNP2 RABEP2 C7orf26 DHRS13 RBAK PRRT3 TTC9 KIAA0556 CTXN1 KLHDC9 NEK5 TTC6 USP42 RALGPS1 TNRC18 MYO5B VPS72 KLHL22 ACVR1B DENND1A LZTR1 ULK1 SNX27 ATP6V0E2 LLGL2 GPRC5C C9orf152 HIP1R HID1 PKP4 KRT19 ESR1 BAZ2A GTF3C1 ERBB3 SH3GLB2 KDM4B ZSWIM8 ANXA9 CACNB3 SCYL3 TBC1D30 RAB3D TBC1D16 MYEF2 PI4KA SMARCC2 TC2N PATZ1 STRBP PYCR1 ATP6AP1 CANT1 HK2 TRAPPC9 SLC25A29 RSAD1 ERGIC1 SOX12 NDUFS8 ADCY6 CAMSAP3 RHPN1 CAPN9 CISH PPP1R16A PRKAG1 ANKRD13D POGZ CYHR1 LONRF2 ATXN7L3B LUC7L3 SLC38A10 LRRN1 RAB40C RUSC1 TMEM229B TRPS1 GGA1 RAB11FIP3	up	***
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_MEDIATED_IMMUNITY	0.0023017	0.0238652	0.4317077	-0.3296176	-1.637209	104	SCIMP GATA2 IL1B CD1C LAMP1 IL23A FGR CLCF1 GATA3 IL18R1 TRAF6 CRTAM TFRC PTAFR FAM49B CADM1 PTPRC FCER1G IL6 CD160 STX7 MALT1 TBX21 TNFSF13 TGFB1 AP1G1 CD1D ZBTB1 CD81 KLRC4-KLRK1 FCGRT IL18 IL18RAP NLRP3 CD1E KLRK1	down	*
REACTOME_TRNA_PROCESSING	0.0024900	0.0253379	0.4317077	0.3868983	1.636816	98	NUP107 METTL1 XPOT QTRT1 PUS7 NUP155 GTPBP3 TPR NSUN2 TRMT61B TRIT1 TYW1 NUP205 RTCB TRMU PUS1 ADAT1 TSEN54 NUP85 ELAC2 CPSF4 AAAS POP7 NSUN6 RPPH1 RPP38 DUS2 NUP62 CTU1 WDR4 SEC13 OSGEP POP4 CDKAL1 NUP210 NUP93 RPP25 CTU2 ADAT3 TP53RK NUP214 NUP37 TSEN15 RPP40 NUP43 TRMT12 URM1 THADA CPSF1 MT-RNR1 TRMT1 NUP35 DDX1 NUP50 NUP133 MT-RNR2 POP1 TRMT44	up	*
GO_DIGESTION	0.0061022	0.0496369	0.4070179	0.4020982	1.636717	76	MUC13 NPC1L1 PRSS2 ADRA2A MUC4 GCNT3 GUCY2C TFF3 SLC5A1 AKR1C1 SOX9 PLS1 MUC6 KCNN4 CEL ADM2 SERPINA3 OXTR CAPN8 PBLD PTGER1 SLC22A5 HIP1R VIL1	up	*
GO_CENTROSOME	0.0000006	0.0000236	0.6594444	0.3304218	1.636225	501	CCNO PKHD1 DDX11 CEP72 SPICE1 MDM1 CEP89 CDC45 RPGRIP1L NEK2 ZNF12 CCNB1 CENPF STOX1 NDC80 MKS1 CCDC113 BRSK1 CCDC14 CNTD2 ASPM STIL TTC26 CEP70 PLK1 IFT27 AURKB ESPL1 CCNB2 PLEKHA7 XRCC2 CCNF DTL CIB1 HNF4G ZFYVE19 CDK5RAP3 DCTN2 SPPL2B NME1 HAUS5 RANBP1 CEP250 WDR62 RUVBL2 HMMR KIF23 CEP55 BBS1 BOD1 CUL7 BICD1 KIF15 KIF3B CCDC13 CCDC77 AUNIP FBF1 MAP10 CCT5 AURKA ODF2 SFI1 IFT43 SNCG KIF2C MAD1L1 POC1A FSD1 HOOK1 DCDC2 GPSM2 MCM3 WDR60 CHEK1 NEK11 CKAP2L TMEM63A RAD18 RABEP2 LRRC45 C2CD3 C4orf47 KNSTRN KRT18 IQCB1 CDK1 CROCC CCDC61 CEP97 CENPJ KIAA0753 POC5 E2F1 PSMB5 ALDOB KIF2A ANKRD26 SSX2IP CCDC88C DYNLL2 SPAG5 POC1B RAB11FIP4 TRAF5 KCTD1 KLHL22 FGFR1OP IFT52 MZT2A MZT2B CEP63 BBS5 CCNE1 CEP192 EXOC7 TUBG1 DLGAP5 NINL TACC3 RAD51D KIF20B JTB TRAF3IP1 SASS6 CKAP5 CDC20 TUBG2 AAAS EFHC1 BCL2L1 CDK5RAP2 ODF2L DYNC1LI2 CDC42BPG CKAP2 CAPRIN2 WDR35 HAUS6 FAM161A KATNB1 HAUS4 MARCKS TCHP CEP152 NUP62 CEP85 B9D1 ALMS1 TTC12 TUBGCP4 CEP164 CLUAP1 NUBP2 HOOK2 CCDC88B TRIP4 FBXW11 MARK4 NME7 CHD3	up	***
GSE24972_WT_VS_IRF8_KO_MARGINAL_ZONE_SPLEEN_BCELL_UP	0.0002415	0.0040411	0.5188481	-0.3149005	-1.635675	160	TMEM150B CPEB2 FABP4 LPXN CGNL1 MYD88 BMPR2 CTDSP1 IL1RN GAS6 FRAT1 LMNA NAAA HSPB1 RNF144B PAG1 ANKRD29 TFRC CSRNP1 CCDC82 SORBS1 AFAP1L1 TMBIM1 DUSP1 ALOX5AP CCDC59 ADIPOR2 USP25 UFM1 DDHD1 JUN MTMR14 IFNGR1 STX5 CD164 STXBP3 NAB1 GATA6 ABL2 CXCR4 VPS4B ZNF471 SSH2 ULK2 CEPT1 DOCK10 EIF4A2 CNN2 KLF15 CHP1 HIPK1 SLC26A11 MT1E FAM160B1 SNX14 MFSD1 MTSS1 RCSD1 ARHGEF12 ATP8A1 RAB39A WDR26	down	**
GO_GRANULOCYTE_MIGRATION	0.0012250	0.0148826	0.4550599	-0.3354038	-1.635343	97	CXCL3 IL1A PECAM1 IL1B CCL3L1 C5AR1 IL1RN IL23A ANXA1 JAM3 PDE4D CCL22 BST1 THBS1 CCL3 CXCL2 CCL4 XCL2 FCER1G AKIRIN1 TGFB2 NCKAP1L HRH1 RAC2 RHOG PTGER4 CCR7 DAPK2 CXCL5 CD74 VAV3 ITGA9 LGALS3 PDE4B CCL20 WDR1	down	*
CAGTATT_MIR200B_MIR200C_MIR429	0.0000006	0.0000230	0.6594444	-0.2824725	-1.635114	395	DLC1 DENND5A OSBPL11 SLC16A12 GATA2 MBOAT2 CORO1C VAT1L CITED2 QKI AKAP7 ELF2 ARL8B NR3C1 OTUD4 RHOA ZEB2 SEMA6D KIAA0355 ASAP1 SERINC1 RANBP9 KLF10 LCP1 DACH1 SRSF2 ZEB1 HNRNPU GPM6A FLI1 LRP4 PPP6R3 KLF4 ZCCHC24 KLF9 MAFG CLIC4 UBQLN1 ID2 RECK UBE2B DUSP1 ADIPOR2 PPP2R5C SLC6A6 FAM76B AFF3 SIAH1 SRF USP25 RPS6KA2 KANK1 PPP2CA ADCY2 PDIK1L PHTF2 APPL1 PIKFYVE HMBOX1 GABPA SLC14A1 ETS1 MAP4K4 CNTN4 FERMT2 NDST1 IP6K1 PPM1F AGFG1 CDK17 YPEL2 YTHDF3 PKIA NAP1L5 ZFAND6 HNRNPD NUP153 PDS5B BAZ2B TSC22D1 KHDRBS1 NAB1 C16orf72 CNOT7 ATXN1 BAG6 TMEM70 TOB1 CLASP2 KAT2B GEM SESN1 RLF VASH1 MGAT2 IER5 MFAP5 UBE2D1 MEX3C BRWD1 HNRNPK SSH2 ULK2 COPS8 MTUS1 MMD NRP2 RHOT1 ZFPM2 WDFY3 BMI1 DNAJB5 EVI5 FEZ2 REEP1 PSIP1 ARHGEF17 CFL2 BHLHE41 CLIP1 HIPK1 UBA6 FHOD1 SLC38A2 FAM8A1 FBXW2 NOG EFNB2 CSNK1G3 CTDSPL2 YWHAB LMO7 C6orf62 UBE2W SGIP1 GOLGA8B TSC22D2 MATR3	down	***
KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	0.0012250	0.0148826	0.4550599	-0.3353310	-1.634988	97	RAMP3 ADCY9 ADCY4 PLA2G10 RAMP2 CALCRL ADRA1D CYP4A11 RHOA ROCK2 PTGIR KCNMA1 ROCK1 KCNMB1 ACTG2 GNAQ MYH11 CALM2 MRVI1 ADCY2 ADRA1A PRKCE NPR1 PRKACA CYP4A22 CALM1 PRKCG	down	*
MYC_UP.V1_UP	0.0007448	0.0100975	0.4772708	0.3697610	1.634586	143	HP SLC29A4 TSFM SORD C12orf66 ECE2 METTL1 SLC27A2 C5orf46 NR2C2AP C19orf48 NLE1 QTRT1 EEF1E1 PUS7 B3GNTL1 SMYD5 DCTPP1 CAPS LRRC61 REPIN1 ALG3 PES1 CCDC78 ISOC2 UNG DGAT2 FAM86C1 PUS1 UBE3D GEMIN5 CGREF1 RRP9 NOL6 WDR83 VWA3B NOC4L EXOSC5 NEFH MMP16 WDR4 FARSB MICU1 VPS9D1	up	*
GO_MICROTUBULE_ORGANIZING_CENTER	0.0000001	0.0000037	0.7049757	0.3249837	1.634484	643	CCNO PKHD1 DDX11 CEP72 SPICE1 MDM1 RUVBL1 CEP89 CDC45 RPGRIP1L BUB1B NEK2 ZNF12 CCNB1 CENPF STOX1 NDC80 MKS1 CCDC113 BRCA1 FANK1 BRSK1 IFT122 CCDC14 CNTD2 ASPM STIL TTC26 CEP70 PLK1 IFT27 AURKB ESPL1 CCNB2 PLEKHA7 XRCC2 CCNF DTL CIB1 HNF4G ZFYVE19 CDK5RAP3 DCTN2 SPDL1 WDR90 SPPL2B NME1 MICALL2 HAUS5 RANBP1 CEP250 WDR62 RUVBL2 HMMR KIF23 CEP55 BBS1 BOD1 CUL7 BICD1 KIF15 TSGA10 KIF3B CCDC13 CCDC77 AUNIP TOP2A FBF1 MAP10 CCT5 AURKA ODF2 SFI1 IFT43 SNCG KIF2C MAD1L1 POC1A AGBL4 MPHOSPH9 TTLL12 TEKT2 FSD1 HOOK1 DCDC2 GPSM2 MCM3 WDR60 TOPBP1 CHEK1 NEK11 IFT172 CC2D1A CKAP2L GAS8 CBY1 TMEM63A RAD18 RABEP2 LRRC45 C2CD3 C4orf47 DLG5 CCDC78 KNSTRN KRT18 IQCB1 CDK1 CROCC CCDC61 CEP97 CENPJ KIAA0753 POC5 E2F1 PSMB5 ALDOB KIF2A ANKRD26 KIF7 SSX2IP CCDC88C DYNLL2 SPAG5 TTC23L POC1B RAB11FIP4 TRAF5 LCA5 KCTD1 KLHL22 FGFR1OP IFT52 MZT2A MZT2B CEP63 BBS5 CCNE1 CEP192 EXOC7 TUBG1 DLGAP5 NINL TACC3 CCDC151 RAD51D CCDC146 KIF20B LRWD1 SMTNL1 CEP128 JTB TRAF3IP1 SASS6 CKAP5 AGBL2 CDC20 WDR34 TUBG2 AAAS FTCD EFHC1 BCL2L1 UBXN6 CDK5RAP2 ODF2L DYNC1LI2 CDC42BPG CKAP2 CAPRIN2 WDR35 HAUS6 NEK4 FAM161A TBC1D30 TMUB1 KATNB1 NEURL4 TTLL6 HAUS4 MARCKS TCHP CEP152 NUP62 CEP85 MICAL3 B9D1 ALMS1 TTC12 TUBGCP4 ICK CEP164 CLUAP1 NUBP2 HOOK2 CCDC88B RAD51 TRIP4 FBXW11 CHMP1A MARK4	up	***
GSE3982_DC_VS_BASOPHIL_UP	0.0000610	0.0012769	0.5384341	-0.3097449	-1.634272	171	KMO SIDT2 PPARG LTA4H TRPV2 CYB5R3 PCOLCE2 CD1C DDO CD36 MAN2B1 ASAP1 HBEGF GM2A ABHD6 RGCC TNS1 GRN SPRY2 ATP6V1B2 ATP10A IL10 SNED1 CCL22 ADO GAA DRAM1 ATP6V1D PDE8A LAMC3 PER2 ATF3 ZBTB43 INHBA MATK CLIP4 ZNF706 GLB1 HCK ESD C1QA HUNK CD83	down	**
LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP	0.0001543	0.0027649	0.5188481	-0.3120677	-1.633942	166	TEK CDH5 ST3GAL6 LDB2 NR3C1 FUCA1 TGFBR2 ZEB2 ERG ASAH1 OLFML2A CYB5A ACOT2 CAV2 TBC1D9 MTMR6 AHNAK SCP2 CPVL ITM2B DAB2 TMED5 PDE8A AXL MATN2 DSTN PPP2R5A ANXA3 CRIM1 EFR3A PRCP FRY ELF1 PDE6B MAGI2 MITF KCTD12 PODXL SDHD ACSL1 PLCG2 MSMO1 GNAI1 LRRC32 TOB1 TSPO ETS2 TNFAIP8 TFPI CEBPD CDKN1C ALDH6A1 SP100	down	**
PID_IL12_2PATHWAY	0.0041334	0.0370962	0.4070179	-0.3703556	-1.633597	59	IL1B CD8A HLX PPP3CA IL18R1 MAP2K3 STAT5A CCL3 NFKB1 CCL4 CD8B IL2RB STAT4 TBX21 FOS PPP3R1 IL18 IL18RAP RIPK2 CD3G ATF2 HLA-DRB1 CD3E CD4 GZMB FASLG GZMA B2M CD3D CCR5 IL1R1 RAB7A IFNG JAK2 RELB	down	*
REACTOME_MITOTIC_G2_G2_M_PHASES	0.0004164	0.0063552	0.4984931	0.3592768	1.633359	179	FOXM1 CEP72 NEK2 CCNB1 CENPF TUBB2B GTSE1 CEP70 PLK1 TPX2 E2F3 CCNB2 CDC25A MYBL2 DCTN2 HAUS5 CEP250 HMMR BTRC AURKA ODF2 SFI1 CDC25C PSMD4 PKMYT1 MNAT1 CDK1 CENPJ E2F1 PSMB5 PSMC4 FGFR1OP MZT2A MZT2B CEP63 CEP192 TUBG1 PSMA5 NINL TUBB2A PSME2 TUBA3D TUBA8 LIN37 PSMD2 PPME1 CKAP5 PSMB3 TUBG2 CDK5RAP2 HAUS6 HAUS4 PSMB4 CEP152 ALMS1 CCNA2 TUBGCP4 CEP164 TUBA4B FBXW11 NME7 TP53 CDC25B TUBA1C CLASP1 FBXL18 CEP290 DYNC1H1 PLK4 AKAP9 PCNT CDK11B PSMB10 LCMT1 TUBGCP2 PSME1	up	**
REACTOME_GPCR_LIGAND_BINDING	0.0000090	0.0002568	0.5933255	-0.2959122	-1.633208	257	FFAR4 CXCL3 HCRTR1 GPR17 RAMP3 CXCL16 EDNRB CD55 F2RL3 LHCGR WNT4 P2RY1 GPR65 RAMP2 HCAR2 CCL3L1 CCRL2 CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 ANXA1 SSTR1 WNT2B GNGT2 FZD4 NMUR1 ADRB1 GNG7 ADRB2 WNT3A GPBAR1 GPR4 PTGIR CCL22 TACR2 PTAFR CCL3 P2RY2 CXCL2 CCL4 PTGER3 XCL2 PTH1R GNRH1 WNT9A S1PR4 HCAR3 TAS1R1 DHH HRH1 ADRA1A PTGER4 CCR7 ACKR3 GPR183 PTGER2 SUCNR1 CXCL5 GPR37L1 WNT11 CCR4 FPR2 GNG5 GNB4 CCR1 GPR18 QRFP CCL20 CCR6 OPN3 HTR6 CXCR4 CCR9 PTCH1	down	***
GO_REGULATION_OF_REACTIVE_OXYGEN_SPECIES_BIOSYNTHETIC_PROCESS	0.0024369	0.0249161	0.4317077	-0.3543637	-1.632675	74	ACP5 IL1B FYN CAV1 RHOA CD36 CLEC7A PTX3 SIRPA IL10 ROCK2 KLF4 TLR4 MIR24-2 PTGIS SLC25A33 CD34 KLF2 PKD2 MPV17L KLRC4-KLRK1 TSPO ICAM1 HSP90AA1 EDN1 KLRK1 CYBA CX3CR1 ATP2B4 DUOXA1 CFLAR PTGS2	down	*
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY5_UP	0.0000635	0.0013191	0.5384341	-0.3093664	-1.632275	171	MCOLN1 TSPAN4 CYP27A1 DPYSL2 FIG4 MSRA CD1C FUCA1 GAS6 EOGT IGSF6 TRIB1 PILRA PLA2G7 SH2B3 MAN2B1 ASAP1 LMNA RNASE1 HLX LAIR1 SIRPA SLC19A1 TUBB6 CST3 EPB41L2 ZMIZ1 YBX3 CPVL GAA SOCS2 CD302 HLA-DQA1 SIAH1 HCK NINJ1 SLCO2B1 VAT1 IFNGR1 CSTA SNX2 CD83 TNFRSF9 RASSF2 PLCG2 TNFSF13 TCF4 MILR1 CD86 ATP6V0C CD81 BMP2K MS4A4A DAPK1 LIMCH1 MAFK MMD CREG1 EHD4	down	**
MORF_BUB3	0.0000549	0.0011683	0.5573322	0.3478886	1.631928	234	GMPS AURKB ESPL1 MCM2 TYMS XPOT ZWINT CCT2 RUVBL2 NUDT1 CHAF1A SDHA BUB1 CCT5 CBX3 NDUFS2 POLA2 MCM7 PRKDC MCM3 DNAJC9 ACTL6A FBL CAD THOP1 ANAPC5 SSBP1 CCT3 GOT2 PMEL FEN1 KXD1 SNRPE RANGAP1 DNMT1 VBP1 ILF2 SNRPA LMNB2 SSRP1 HDAC1 TCEA1 DAP3 DNAJC11 CCT7 BRD8 ACLY MCM6 MCM5 LSM7 SRSF1 HAX1 AATF POLR2I SLC1A5 LSM4 TXNL4A SF3A2 EIF3K NDUFV1 GLO1 MSH2 DOCK3 VDAC1 PRPF31 UQCRC1 MRPL9 SNRNP200 ACP1 TMED9 UBAP2L VDAC3 PAICS CHERP MRPS27 GPN1 SF3B2 MAP2K2 LYPLA1 AKR7A2 DRG1 DGUOK SRM CLPP TNPO3 SAFB EDC4 CS SEC24C XRCC5 NAE1 HNRNPAB LRPPRC SRSF9 PPP2R1A CALM3 DDX49 FIBP XRCC6 STMN1 PSMD8 PPM1G KHSRP BUB3 ATXN10 HNRNPUL1 TRIM28	up	**
GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN	0.0000643	0.0013316	0.5384341	-0.3092669	-1.631750	171	NLRC4 KMO TMEM52B CYP27A1 TMEM170B FYN CCDC88A NEDD4L DNAJB14 ASAH1 PBX3 CAMTA1 ADIPOR1 SLAIN2 PPP3CA MPHOSPH6 TCF7L2 TAPT1 AGO3 THBS1 PDE8A NR1D2 PINK1 FAM76B CNOT6L CDKN2AIP HAUS1 CDC40 RAB8B C2CD2 DESI2 MED30 UBAC2 PTGER2 SNX1 PRKACA TRAK2 ZBED5 GAS2L3 ECI2 ATG2B CD81 SERINC3 CCNH INTS6 CPQ CEP170 TRAPPC8 MEGF9 MEX3C CEPT1 NFU1 SPATA5L1 SPOPL CHML SLC19A2 MAPK1 MZT1	down	**
GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP	0.0004099	0.0062746	0.4984931	0.3609876	1.631660	170	CEP72 MCM10 POLQ PBK PRIM2 GINS1 CDK4 AURKB SFXN1 CCNB2 UMPS SHMT2 RANBP1 NUDT1 CISD1 AURKA EME1 POLD2 MCM7 RRM2 SMYD2 CCDC58 ORC6 FBL SPC24 DSCC1 CAD RAD18 PPIL1 CKS1B ASF1B CDK1 POLE2 UCK2 BIRC5 GMNN ADAP1 MECR NF1 PSMC4 CENPP POLL TK1 MFSD2A GEMIN5 AGPAT5 PRMT7 POLD1 POLB CLTB GEMIN6 FAM136A SNRPD1 LSM7 PRIM1 BANF1 RFC5 RAD51 SEC13 ZMYND19	up	**
GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN	0.0002039	0.0034964	0.5188481	-0.3071641	-1.631628	179	EPAS1 ACP5 STAC PPARG FBP1 CYP27A1 DCSTAMP TRPV2 ENG CORO1C ALAS1 LAMP1 PFDN1 AVPI1 HSPE1 NDUFAF1 ARSB LMNA GM2A CSRP1 CYB5A HSPB1 CRTAM TFRC SETD3 FABP5 ACSL3 PXDC1 PARVB ATP6V1D RMDN3 CLIC4 CTSD PAPSS1 EFR3A PI4K2A HEXB TECR MITF VAT1 ST6GALNAC4	down	**
GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN	0.0001120	0.0021237	0.5384341	-0.3068222	-1.631367	175	TUBD1 OSBPL1A MMRN1 ASAP1 MCTP1 MTF1 KLF6 MPHOSPH6 CRK CCNI ROCK2 DUSP3 CASP1 RNFT1 DAB2 KLF7 SCAF4 PDE8A RBMS1 SELP KCTD20 CD53 ADIPOR2 GNAQ KPNA3 LMBRD1 NCOA1 PIAS1 TBC1D5 MOB4 RBPJ ARL6IP5 CDC40 GABARAPL2 ESD PSMA1 GSTO1 FBXO11 GMFG REL AP3B1 UVRAG POGLUT1 SPOP SAV1 STRN MR1 SYT11 CPQ ARPC2 CALCOCO2 C21orf91 PAPSS2 AFTPH PUS3 TMEM50A SAP18 EXPH5 CLOCK	down	**
LI_DCP2_BOUND_MRNA	0.0050730	0.0433281	0.4070179	0.3999140	1.631250	75	PHGDH TRIB3 RUVBL2 CHAF1A TPR MRPS11 TST FAHD2A PI4KAP1 NARF TSPAN31 MRPS12 ETFB DGCR6 NDUFA13 DUS1L UBXN6 NDUFS7 NT5DC2 AP2S1 SCO2 UQCRC1 DLEC1 CHMP2A NDUFS8 ENO1 NDUFB7 C12orf10 MAP2K2 APEH MRTO4 MRPL12 APRT	up	*
MIR497_3P	0.0000593	0.0012455	0.5573322	-0.3007297	-1.631205	203	KLF13 TBX3 CPEB2 CLDND1 ZBTB34 BAIAP2 RXFP1 NR3C1 VAPA TMX4 CNST LIFR TCF7L2 FOXO1 SGTB FAM124B KLF4 PAQR5 ATG7 UBE2E2 GPR85 C9orf72 IL7R ARHGAP17 SPIN1 RBPJ PDCD6IP HECA LRCH1 GABPA MSRB3 CYCS WTAP SNX2 STX7 SP3 PCGF5 CREB1 YWHAZ ACSL1 AGPS PTP4A1 MAPK8 TMX3 CEP76 C16orf72 RELL1 SLC24A1 PPIL3 KAT2B SERINC3 MBNL1 ATAD2B SMAD2 INO80D AMD1 INTS6 SLC31A1 SPARCL1 MRPL1 RTN1 RTN4 MAP3K4 TBCEL PAK2 CNN2 EIF4G2 SCLT1	down	**
MORF_MTA1	0.0030944	0.0298591	0.4317077	0.3917199	1.631117	88	COIL GGCT XPOT DCTN2 SDHA ACTL6A CNOT3 TMEM106C PABPN1 ILF2 SNRPA TCEA1 SLC4A2 RPA1 MRPL28 POLR2I PSMB4 NUP62 NDUFV1 DOCK3 BANF1 PDAP1 FBXW11 MRPL9 SRP9 SNRNP200 UBAP2L PWP1 ILVBL SART3 MAP2K2 PRKAG1 LYPLA1 AKR7A2 XPO6 DRG1 FAM120A SHMT1 CS HNRNPAB PPP2R1A FIBP PPM1G RAC1 ENSA ARF3 PIGC HDAC2 NCBP2 SMG7 KDELR1 CTDNEP1 COX5A CANX	up	*
GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_DN	0.0012226	0.0148675	0.4550599	-0.3229486	-1.631049	123	TRHDE KCNA2 GIMAP8 INSIG1 GPC5 TMEM170B SH2D3C GFOD1 FOSL1 NEDD9 AGPAT4 TTL FAM89A TMEM74B PRSS12 RHOB FABP5 CFD ITPRIP PLAUR ID3 KLF11 DRAM1 SPAG9 DUSP1 CPT1A GPR157 MAFF NINJ1 IL6 VPS37A MN1 RBKS ISM1 SH3RF3 DUSP5 PDCD1 C8orf37 GEM MRPL1 NLRP3 ST6GAL2 B3GNT2 GCNT7 ZFPM2	down	*
GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN	0.0001171	0.0022038	0.5384341	-0.3097387	-1.630930	170	LPIN2 SLC12A6 GIMAP8 OTUD1 LMO2 YPEL5 C8orf58 HPS5 RCHY1 GGA2 CASP9 PDE2A ZBTB4 B3GNT5 LATS2 KLF6 MS4A1 CLK1 HERC3 RRM2B STK17B CDS2 HPSE PNRC1 CLK4 CD53 MBD2 LMBRD1 HEXB BTG1 MYLIP CREBRF FRY GZF1 C20orf194 ETS1 OSBPL9 DDX17 EPC1	down	**
GO_CXCR3_CHEMOKINE_RECEPTOR_BINDING	0.0056901	0.0470661	0.4070179	0.8679573	1.630922	4	CXCL10 CXCL9 CXCL11	up	*
GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION	0.0004582	0.0068534	0.4984931	-0.3184738	-1.630591	146	TNR SWAP70 CCM2L ADTRP SPN RDX BMP2 MYADM PRKAR1A CD9 IL1RN ANXA1 MIR146A SH2B3 HLX PAG1 RGCC IL10 NRARP DUSP3 KLF4 SOCS5 SFTPD SMAD7 UBASH3B GNRH1 CD80 PDE5A PODXL RC3H1 TBX21 TIGIT PPM1F PELI1 MBP RUNX3 CD74 TGFB1 YTHDF2 LRRC32 MIA3 CD86 LGALS3	down	**
GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP	0.0006851	0.0094802	0.4772708	0.3620062	1.630499	159	SAA2 KIF20A ADH1C LAD1 CEP89 MCM10 BDH1 PSPH SCN3A COLQ SFXN1 FIGNL1 ANKRD22 RBBP8 SMPDL3A EIF3B MYL6B NUB1 CASP2 HMMR COPG2 CEL RAD54L KIF11 SIDT1 KHK SLC45A3 EDN2 BTBD2 CDKN2C CDK1 ZMIZ2 OAT NEIL3 OARD1 TRAF5 TCTE1 MNS1 ARL6IP4 FBXO4 MRPL4 SND1 COPS6 CHTF8 SLC41A3 CATSPER1 MRPL14 HLCS RDH10 NDUFA8 NDUFS8 AGBL5 UBAP2L	up	**
GSE36826_WT_VS_IL1R_KO_SKIN_DN	0.0001672	0.0029595	0.5188481	-0.3113578	-1.630225	166	CD101 OLR1 SPN PID1 EMCN BACH1 AQP9 C5AR1 RBM14 CDC42 RFTN1 CD5 MTF1 ANPEP SLC7A11 LCP1 SLC25A37 MCL1 CD58 THBS1 SCAF4 CDKN1A COTL1 VIM CD53 DUSP1 DSE SRF EMP3 FRY PSMA1 TREM1 RHOG PPP1R15A IDS CDK2AP2 REL CGGBP1 CST7 PPM1F CDK14 SLC3A2 HNRNPA2B1 NAB1 PITPNA TXNDC15 MGAT2 ITGAE ACTB TRAF1 SRSF10 PDE4A DNAJB5 EIF4G2 PPP1CB AFTPH DUSP6 SH3BGRL3 TMEM43 FHOD1 FPR1 PTGS1 GNG11 LAMP3 DDX21 TES STARD5 IRF4 MSC GPATCH2L EMP1 PNP	down	**
ROSS_LEUKEMIA_WITH_MLL_FUSIONS	0.0037737	0.0347073	0.4317077	-0.3591099	-1.629904	69	SIDT2 ADCY9 CORO1C ZEB2 PBX3 ANXA5 DACH1 CES1 SCP2 DAB2 PTPRC CCND2 HEXB ARL6IP5 RAC2 RBKS NKG7 WHAMMP3 MEIS1 CLASP2 ADAM10 MBNL1 ARPC2 SCPEP1 JMJD1C KLRK1 FEZ1 BMI1	down	*
GSE30083_SP3_VS_SP4_THYMOCYTE_DN	0.0001509	0.0027161	0.5188481	-0.3076177	-1.629750	173	FAM167A ST8SIA6 HHEX ZC3H12C SNX10 CD44 LY86 CTSW CLEC10A IL1RL1 TEX2 GM2A LITAF CYB561A3 LAIR1 IL18R1 GRN SPRY2 CYP4V2 RHOB EVI2B AHNAK MPEG1 CASP1 RNFT1 RRM2B HOPX HPSE PLEK KLRD1 DSE UBASH3B TDRD7 TBC1D5 S1PR4 SGK1 IL2RB STAT4 TYROBP IRF8 FAM43A TBX21 RHOQ NKG7 RIN2 PEA15 KCTD10 KCNN2 ZC3H12D TAGAP N4BP2L2 RXRA GEM IL18RAP IER5 ITGAE	down	**
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP	0.0004832	0.0071444	0.4984931	0.3613445	1.629744	168	HABP2 BUB1B NUP107 TIMELESS TRAIP PMS2P5 SAYSD1 DNAH3 DPYSL4 ORC1 DTL LIME1 MRPS35 CHAF1A KCNMB3 SETDB1 RAD54L SALL2 WDR60 SLC9A3R1 DET1 ANAPC5 TNFRSF25 AAGAB EZH2 ETFB CCDC57 PA2G4 ZNF606 DCLRE1C TAPBPL DHX40 ADAM28 MC1R ARHGAP32 SLC37A4 SCN8A MGMT ACAD10 DAP3 ENOSF1 CDK13 CNDP2 CCT7 PPP1R8 MCM6 ZNF248 TRANK1 MCM5 HMCES EDAR C1QTNF3 ALOX12P2 MSH2 TM7SF3 TUBGCP4 CDK5RAP1 ABHD10 TRAPPC9 MICU1 SNRNP200 CELSR2	up	**
GSE7509_DC_VS_MONOCYTE_UP	0.0001536	0.0027576	0.5188481	-0.3061955	-1.629618	177	TSPAN4 LTA4H THBD LPL HSD17B11 LY86 SRSF7 ARL8B ALAS1 ANXA1 HBEGF ENTPD1 GM2A ANXA5 LITAF CST3 FABP5 NES DAB2 PLBD1 CTSD CADM1 ITGAX ATF3 PER1 ACTG2 IL7R PTGIS PI4K2A GLB1 HGSNAT RPS6KA2 DCTN6 C1QA ST6GALNAC4 UVRAG CEBPZ FOXO3 NDUFA5 TEC UTP3 LGALS3 GABARAPL1 RGS2 GTF2B SESN1 GSTM5 CDC16 CDKN1C TMEM109 TIMP3 PSMD6 CREG1 CNN2 UBAP1 SPSB1 CSF2RB C1QB CRTAP CTSH	down	**
REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	0.0012515	0.0150975	0.4550599	0.3761743	1.629231	121	BUB1B NUP107 CENPF NDC80 TUBB2B PLK1 NUF2 CDCA8 AURKB CENPA DYNC1I1 ZWINT SPDL1 KNTC1 BUB1 CENPL KIF2C MAD1L1 PFN2 MAD2L1 CENPO SPC24 INCENP CENPH BIRC5 KIF2A DYNLL2 DIAPH3 CENPP RANGAP1 RHOC DVL3 TUBB2A TUBA3D TUBA8 CENPQ NUP85 CENPK CKAP5 CDC20 CENPM DYNC1LI2 CENPT	up	*
GO_AMYLOID_BETA_CLEARANCE	0.0054319	0.0453807	0.4070179	-0.4329675	-1.629219	34	C5AR1 HMGCR MARCO CD36 PICALM LRP4 MSR1 ROCK1 SRF IFNGR1 MME MYOCD RAB5A LDLR TREM2 CYP51A1	down	*
GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP	0.0004209	0.0064022	0.4984931	0.3604419	1.629194	170	CUZD1 TICRR JPH3 PSPH KIF18B TTK CDCA2 GTSE1 KIF14 STIL IGSF11 CCNF CCT6A WDR62 NDUFB8 EXO1 KIF23 BUB1 AUNIP MCM7 ZNF146 MRPL27 PASK FANCD2 CHAF1B SPC24 BRIP1 IDH2 HDGF CENPJ UCK2 SPAG5 RAB11FIP4 DIAPH3 PA2G4 CCNE1 TSPAN17 ST14 NMRAL1 MBD4 HIRA CLTA SAP30	up	**
GSE2585_CD80_HIGH_VS_LOW_MTEC_UP	0.0011204	0.0138754	0.4550599	0.3700907	1.629042	132	COL17A1 SHISA3 ZNF12 CIB2 COL27A1 GCNT3 THEM5 IRS1 ABCA12 BCAS1 ENAM LAMP5 SLC6A3 CYP27B1 ASPHD2 CCDC150 SDR16C5 ANO9 RND2 TSGA10 FLG TOM1L1 DCDC2 ASB16 PROB1 NRG4 DLG5 FAT1 SCTR TMEM182 POLR1C C9orf43 LAPTM4B ILF2 ASGR2 OS9 PCDH9	up	*
REACTOME_SIGNALING_BY_INTERLEUKINS	0.0000020	0.0000707	0.6272567	-0.2816721	-1.628861	365	IL17RB IL1A HMOX1 IL1B FYN CCL3L1 MYD88 VAMP2 S1PR1 MEF2A CDC42 IL1RL1 IL1RN PSMD5 CBL IL23A CD36 ANXA1 CLCF1 LIFR MAP3K8 LCP1 GATA3 IL18R1 TRAF6 HNRNPDL CRK ZEB1 MCL1 PTPN12 IL10 MAP2K3 STAT5A DUSP3 CCL22 FOXO1 CASP1 PTAFR STX3 SOCS2 SOCS5 CCL3 NFKB1 CDKN1A ITGAX NKIRAS1 CXCL2 IRAK2 VIM CCL4 IL7R CA1 IL24 HCK RPS6KA2 CD80 CNTF PPP2CA IL6 SOCS3 IL2RB JUN PSMA1 STAT4 JUNB JAK1 RAPGEF1 GSTO1 PIK3R1 GRB2 CREB1 OSM RPS6KA1 PRKACA TCP1 YWHAZ FOS UBB PELI1 PSMD12 FOXO3 MAPK8 PPP2CB TGFB1 HNRNPA2B1 TEC CD86 IRS2 PIM1 SOD2 CCR1 IFNLR1 CCL20 PITPNA ICAM1 FGF2 IL18 IL18RAP CEBPD HSP90AA1 TAB2 RIPK2 HSPA8 HAVCR2 BRWD1 PSME4 NFKBIA PAK2 DUSP7 RORA PSMD6 PSMD9 IL16 CNN2	down	***
GO_CHYLOMICRON_REMODELING	0.0041562	0.0372489	0.4070179	-0.9219954	-1.628571	3	GPIHBP1 LPL	down	*
REACTOME_CHYLOMICRON_REMODELING	0.0041562	0.0372489	0.4070179	-0.9219954	-1.628571	3	GPIHBP1 LPL	down	*
GO_NEGATIVE_REGULATION_OF_AXONOGENESIS	0.0043858	0.0388311	0.4070179	-0.3691764	-1.628396	59	TNR DAB1 SEMA6B SEMA3G SEMA6A RHOA SEMA6D SEMA3B WNT3A LRP4 PTPRO TRIM46 RUFY3 PSEN1 IFRD1 RTN4R TRAK2	down	*
GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS	0.0000000	0.0000001	0.7881868	-0.2609417	-1.628321	744	SLC6A4 TNR SMAD6 LIMS2 ANGPT4 DAB1 RBP4 SEMA6B SEMA3G SEMA6A EREG ACVRL1 SOSTDC1 TEK EDNRB DENND5A TAL1 KLF13 PPARG HHEX TBX3 GATA2 IL1B TIE1 WNT4 RAPGEF2 BMP2 INSIG1 FIG4 BDNF ARHGEF15 ECSCR SOX17 DDX6 CAV1 CORO1C BMPR2 GTF2I CTDSP1 TBXA2R FGF10 MIR27B GAS6 TGFBR2 NFATC3 TRIB1 LILRB3 HSPG2 RHOA SEMA6D ANXA1 TBX2 WWC2 MIR146A MYOZ1 MMRN2 FBXO7 ASAP1 PTPRM SEMA3B FOXA2 ABCG1 PAQR3 HLX ADIPOR1 EIF4E ADRB1 GATA3 PPP3CA RB1 RGCC ADRB2 NFE2L2 SFRP1 AKT3 SPRY2 WNT3A ZEB1 SRGN ARHGEF2 HNRNPU ZNF365 FOXC2 NODAL CST3 LRP4 GPR4 ROCK2 SNAI1 NRARP FOXO1 PTPRO TRIM46 DAAM2 YBX3 KLF4 RUNX1T1 REST ID3 ROCK1 ZADH2 THBS1 ARNTL ADAMTS9 SOCS2 CLDN5 SOCS5 KLF7 CCL3 CDKN1A PDE3B VIM HOPX ID2 TLR4 MIR24-2 LBH SMAD7 INHBA PINK1 TBX5 ZNF706 UBASH3B PAFAH1B1 RUFY3 HES1 MIR17HG AKIRIN1 KREMEN1 ARHGDIB TGFB2 GNRH1 SRGAP2C KANK1 MYLIP RBPJ WNT9A IL17D ID4 CNTF PPP2CA AREG IL6 YBX1 CD160 MED28 PSEN1 VAT1 NOTCH1 LIMD1 GABPA CUL4A CTSZ CNTN4 BAG5 SKIL IFRD1 PIK3R1 LSM1 NPR1 RC3H1 RTN4R PRKACA TRAK2 FSTL3 TBX21	down	***
GO_NUCLEOTIDE_PHOSPHORYLATION	0.0016653	0.0186190	0.4550599	0.3801711	1.627554	109	HKDC1 AK4 NUP107 PGM2L1 DDIT4 GPI GAPDH ALDOC AK8 NME1 NUP155 TPR NME9 PKM NME5 PFKP ALDOA ENTPD5 GCKR ALDOB BPGM NUP205 AK7 PRKAA2 EIF6 FOXK1 DTYMK NUP85 DHTKD1 AAAS PFKFB4 ESRRB NUP62 NME4 HK2 SEC13 PFKM NME7 PGAM1 SIRT6 PNKP ENO1 NUP210 NUP93 PRKAG1	up	*
MIR518E_5P_MIR519A_5P_MIR519B_5P_MIR519C_5P_MIR522_5P_MIR523_5P	0.0052105	0.0441207	0.4070179	-0.3611961	-1.627521	68	SEMA6A TMEM170B JPH4 MED4 NCEH1 ECHDC1 LCP1 TFRC FLI1 HMGN1 PTPN21 ZSWIM6 CLK4 SLC25A33 CREBRF PLGLB1 CHORDC1 SAV1 ZCCHC10 EWSR1 RELL1	down	*
E2F1_Q6	0.0004238	0.0064363	0.4984931	0.3525242	1.627203	198	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 ORC1 C19orf57 MCM8 CAND1 EPHB1 CDT1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 CACNA1G MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2	up	**
GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN	0.0007328	0.0099608	0.4772708	0.3586019	1.627184	176	HMGA2 CCDC162P CDC45 CCDC127 THOC3 NDUFS6 GPI MCM8 ZFYVE19 COQ3 DCTN2 TAMM41 MRPL15 EME1 CBX3 POLD2 RAB19 CDC25C ABCB6 CKAP2L TIMM50 CMAS POLR3K ACTR3B OCIAD2 KCTD1 VIPAS39 GNPAT SCLY MRPL11 TRIM37 DTYMK C1orf131 DAP3 LIN37 TEKT3 CENPM STOML2 ZCCHC17 FAF1 CKAP2 TDP1 SNRPD1 MALSU1 EIF3D EIF3K SHCBP1 PRPF31 HOOK2 MRPL9 NDUFS8 WDR76 NMT1 NUP93 PPP1R14B VNN1 MAP2K2 ACSL5 TRAPPC6A TIPRL DRG1 PLK4 DFFB LCMT1 TOMM40 KIAA1841 MCEE HSD17B7 TLCD1	up	**
GO_INTERLEUKIN_8_PRODUCTION	0.0044489	0.0392395	0.4070179	-0.3688778	-1.627079	59	FCN1 IL1B MYD88 ANXA1 MIR146A CD33 CLEC7A CD58 IL10 ARRB1 KLF4 PTPRC TLR4 IL17D HSPA1B	down	*
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY10_DN	0.0001301	0.0024046	0.5188481	-0.3089721	-1.626894	170	ABHD5 MNDA SNX10 TRPV2 MYD88 STX11 ALAS1 IL1RN PSMD5 SPG21 GRN TXN TUBB6 ATP6V1B2 TBC1D9 KIAA0513 CASP1 PTAFR PLAUR STX3 RMDN3 CLIC4 CDKN1A CDS2 INHBA DSE USP25 PGD RAB31 HK3 ATP6V0B TYROBP DNAJA1 KLHL18 OGFRL1 CGGBP1 ACSL1 RHOQ ATG3 RIN2 SORT1 DUSP5 CD86 ATP6V0C SOD2 CCR1 KYNU GEM SLC31A1 RTN1 LRP12 CALCOCO2 NLRP3 GLRX2 MT2A CREG1	down	**
CAMP_UP.V1_DN	0.0001185	0.0022216	0.5384341	-0.3058875	-1.626398	175	LRRFIP1 INSIG1 MED4 NCF2 EPB41L3 ANXA1 ATP2B1 BZW1 SERINC1 GLS EIF4E SRSF2 AKT3 CLK1 ZMIZ1 TJP1 MYO15B TMBIM1 NFKB1 UBE2E2 PTPRC ID2 CCND2 PLEK MBD2 PINK1 GNAQ IL7R BACE1 SNN FOXN3 FRY CD160 RGS18 RAB31 MAP4K4 DNAJA1 MTMR9 MPZL3 CD83 IDS CELF2 PELI1 CALM1 FOSB PKIA TIMP2 TSC22D1 BAG6 SPOCK2 ETS2 PRDM8 SYT11 GEM RNF138 MIR155HG HSP90AA1 ESYT1 CCR9 HSPA8	down	**
ACTGTAG_MIR139	0.0026112	0.0262135	0.4317077	-0.3273935	-1.626162	104	HMGCR CDC42 ZEB2 UBR3 CACNA2D2 FOXP1 BTG3 SOCS2 MGAT4A FRMD4A RUFY3 FAM76B SLC25A3 PPP2CA CCNY JUN NOTCH1 CPEB4 ETS1 DHX15 FBXL16 KBTBD8 FOS AZIN1 AKIRIN2 SRSF4 TGIF1 RSBN1L ATXN1 APLP2 GPD1L PSME4 SRSF10 KPNA4 PDE4A PIEZO1 EIF4G2 JDP2 HIPK1 CTDSPL2 WDR47	down	*
MIR1277_5P	0.0000000	0.0000001	0.7881868	-0.2615998	-1.625872	746	SMAD6 EREG GCOM1 EDNRB SGK3 KCNA2 ZC3H12C CPEB2 PRKG2 P2RY1 RDX NUP54 DPYSL2 PTPRE ST6GALNAC3 BMP2 KL BDNF PLEKHF2 MYADM NEDD4L QKI VAMP2 MEF2A RXFP1 KCNN3 NR3C1 TGFBR3 DSCAML1 TET2 MOB1B PILRA TEX2 ZEB2 DNAJB14 TXNIP NUMB KCNAB1 BRINP3 CD36 ANXA1 SSTR1 HBEGF SBDS TACC1 FOXA2 LIFR RAP1A PPP1R15B CHMP1B PLXNA2 SWT1 EMILIN2 BTG2 ZDHHC2 MAP3K8 ANXA5 NLK CSGALNACT2 KLF6 CAMTA1 SLC7A11 DACH1 FOXJ3 NR4A1 RGCC TRAF6 SPRY2 TFEC SRGN GPM6A KDSR CPED1 ROCK2 SNAI1 TLE4 TBX4 ZSWIM6 PEG3 RRM2B VASP ADAMTS9 GAPVD1 RIT1 CDS2 C9orf72 RECK CCND2 ACTR3 EPS15 CCSER2 DUSP1 PIK3C2A ELK3 SMAD7 BRF2 LYAR EXOSC8 TBX5 TM9SF2 SPRYD7 AFF1 NCKAP5 EFR3A KREMEN1 LIN7A AFF3 NCOA1 FAM102B SLC25A3 FMNL2 HESX1 PRDM11 PDIK1L VPS37A SYNPO2 PHTF2 KIF13A PHACTR2 PIKFYVE UTRN NECAP1 SERPINB8 TMTC1 ARL5B MITF GABPA ETS1 PDE5A MSRB3 FOXN2 DUSP8 SKIL ENPP4 FBXL16 ACKR3 SMU1 PCGF5 HERC1 ZNF804A IDS CREB1 COBLL1 RC3H1 SNX1 FSD1L DOCK8 HOMER1 ZNRF3 SUCNR1 CXCL5 PREX2 DENND4A BLOC1S6 SLC25A24 PELI1 NECAB1 NAPG FOSB RIN2 ZNF521 UBXN2A SAV1 TMX3 TCF4 STRN NR2C1 ZBTB1 TGIF1 RSBN1L TEC ZBTB11 CNOT7 HBP1 CNTNAP1 PLSCR4 THAP9 ADPGK TOB1 NPTN RIMKLB CSNK2A2 KAT2B SERINC3 CCNH INO80D HACE1 GEM LDLRAD4 INTS6 NEK1 ABL2 FKBP1A SF1 OPN3 CALHM2 SETDB2 CDC42EP3 MFAP5 EPHA4 SIK3 USH2A MEX3C POLR2M NUP98 EPHA2 SCPEP1 CREBBP PARVA DAPK1 STAM2 NEK3 LYSMD3 CUL3 RASSF8 TTC28 ZDHHC5 SCAI PTEN TNFSF9 MMD SAMSN1 C21orf91 FGFR1 RORA FAM13C DAZAP2 LDLR RHOT1 WDFY3 EVI5 ZBTB44 CSF2 STARD13 SPSB1 PLAG1 CDON SERPINE1 SVIL UBA6 CLOCK RB1CC1 SLC38A2 KIAA2026 ALG2 EXOC8 HP1BP3 ZFP36 PLXDC2 EFNB2 BBS7 PIGK ADAMTSL3 DNAJB4 CTDSPL2 PPIP5K2	down	***
GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_UP	0.0004771	0.0070746	0.4984931	0.3575937	1.625707	179	SAA1 CDH17 PHGDH ECE2 METTL1 ALDH18A1 CDC6 CDC25A ACY1 CCT6A MCM8 SHMT2 EXO1 C19orf48 IDO1 WDR3 CCDC58 AIMP2 C7orf50 DNAH11 ALG3 DDX56 MRPL37 HDGF EXOSC2 DTD1 CCT3 ATIC UNG MRPS2 ATAD3A NOP2 DDT FAH YDJC C12orf45 DBN1 ZNF239 MFSD2A DNAJC11 MAGOHB AHCYL1 GPATCH4 PRMT1 BSN TMEM147 SURF2 CLUH DUS4L POLR2I POLR3E SF3A2 TSR1 PRMT5 USP39 WDR77 HK2 POLR1B MRPS27 MUC1 FTSJ3 PCGF6 CLNS1A MRTO4 WDR55 MED22 SFXN2 SHQ1 SRM PARL ADSL APRT SNHG17 TIMM10 SAMD11 MRPS6 RBM8A TIMM9 EBNA1BP2 COQ4 CTPS1 EEF1D EXOSC7 DNAJC2 GRWD1 NUP43 RRP1B IDH3A CHCHD4 PUS7L HTR7 AEN PECR PLSCR1 GART PSME3	up	**
GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	0.0002406	0.0040285	0.5188481	-0.3061764	-1.625444	174	WEE1 ARHGAP31 PTP4A2 FYN PDE1B KIAA1109 CORO1C FLVCR2 NR3C1 TGFBR3 GGA2 TMX4 ASAP1 PTPRM CD5 C1orf21 PICALM CAMTA1 RB1 CD58 EFCAB14 AGO4 KIF1C DENND3 COTL1 EPS15 ALOX5AP PPP2R5C SLC6A6 CRIM1 MYO1C PHACTR2 CPEB4 GTDC1 TNFRSF9 CCR4 SAV1 BAZ2B ATXN1 SYT11 MGAT2 NLRP3 GLUL CCDC92 ABI3 AIM2 KIF1B IQGAP1 LPAR6 PIEZO1 SLFN11 KLRF1 SPSB1 UBR2 ZBTB16 CCDC112 AOAH KIAA2026 FAM53B RCBTB2 ATP2B4 KATNAL1 USP45 CFLAR AKAP13 FAM89B BMPR1A MYO5A GALM	down	**
FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP	0.0000001	0.0000050	0.7049757	-0.2734227	-1.624111	507	SMAD6 RAB11FIP1 CXCL3 EREG ZNF366 PNPLA6 IL1A STAC OLR1 ADTRP CD55 SOWAHC IL1B LRRC8C DCSTAMP THBD LPL GFOD1 ST3GAL6 LONRF1 NEDD4L YPEL5 VAPA IL1RN SCARF1 IGSF6 ACER3 DNASE1L3 SNHG5 EDEM1 ARHGAP10 PTS ASAP1 B3GNT5 HBEGF RILP NAAA CLEC7A CSRP1 BTG2 COX18 GLS SLC7A11 ZNF697 PPP3CA RGCC MPHOSPH6 CD93 SPI1 TUBB6 CCNI CPED1 EFCAB14 TAPT1 TIMM10B CCL22 PTPRO MPEG1 ACSL3 PLAUR ST3GAL2 PRKD3 SLC7A8 VASP SOCS2 DPH3 CXCL2 HOPX UXS1 SMAD7 EVI2A INHBA SLC6A6 GPR157 IL7R PEF1 NUS1 TBC1D4 MAFF CRIM1 AKIRIN1 MOB3A MMP19 FAM102B FOXN3 PROCR CLN8 TRGC2 HCAR3 FMNL2 IL6 PHTF2 BCAR3 PHACTR2 AQP3 PPA2 ETV3 JUN MTMR14 SH3BP5 RAB31 RAC2 TREM1 PLK3 RCAN1 GLIPR1 LYRM1 SIGLEC15 ENTPD4 FSD1L REL CXCL5 TNFRSF9 SMIM20 LGALS2 TAGLN2 CST7 WDFY4 NDUFV2 SLC3A2 POGLUT1 RHOQ CALM1 TNFSF13	down	***
MORF_RAD54L	0.0053099	0.0447408	0.4070179	0.3901096	1.624088	87	TRIP13 BUB1B MCM2 SRPK1 ZWINT RUVBL2 CHAF1A PRKDC TRRAP RAD54L ACTL6A PKMYT1 CAD ALG3 THOP1 PABPN1 SSBP1 GOT2 DNMT1 SSRP1 MLEC KIF20B DNAJC11 CDC7 NUP62 BMS1 VDAC3 ZNF131 MZF1 XPO6 TNPO3 SAFB CS NAE1 LRPPRC	up	*
GO_POSITIVE_REGULATION_OF_CARDIAC_MUSCLE_ADAPTATION	0.0044854	0.0394933	0.4070179	-0.9193724	-1.623938	3	TRPC3 PPP3CA	down	*
GO_COAGULATION	0.0000091	0.0002583	0.5933255	-0.2940697	-1.623625	260	CLEC1B ADTRP GATA2 F2RL3 P2RY1 THBD RCOR1 TRPC3 FYN MMRN1 CAV1 TBXA2R PRKAR1A CDC42 CD9 GAS6 HPS5 PEAR1 CD36 SH2B3 FOXA2 ENTPD1 CSRP1 HSPB1 ANXA5 SLC7A11 GATA3 NFE2L2 WNT3A PDGFA ARRB1 DGKE PLAUR THBS1 MAFG MPL ITPK1 DOCK9 SELP AXL HPSE TLR4 CAPZA2 FCER1G PLEK GNAQ UBASH3B PIK3R5 C4BPB MAFF VWF PROCR SRF PRCP METAP1 IL6 PSEN1 ENPP4 PIK3R1 PABPC4 PRKCE PRKACA DOCK8 AP3B1 YWHAZ CD34 PLCG2 EHD2 PRKCG MYL12A DGKG STXBP3 EHD1 VAV3 TEC GATA6 GNA13 DOCK6 TFPI ARRB2 RAB5A ACTB ADORA2A JMJD1C MAFK EDN1 SCUBE1 PRKG1 P2RX1 ZFPM2 EHD3 ANO6 PAPSS2 IRF2 SERPINE1 TREML1 CAPZB MAPK1 PRKCH	down	***
GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN	0.0004881	0.0072048	0.4984931	0.3570507	1.623238	179	RIBC2 GMDS BDH1 TIMELESS KIF14 TTC26 PLK1 CENPA TYMS ACY1 SPDL1 AGK KIF23 KIF15 TOP2A RRM2 RAD54L MRPL3 CDC25C KDELR2 ORC6 EHHADH DCTPP1 ETFA BLM CKS1B EFCAB11 NCAPG2 CDK1 UNG PSMB5 OARD1 SNRPE RTCB PA2G4 RNASEH2A VBP1 UQCRFS1 TACC3 MRPL11 HIRA GINS2 KIF20B LAMTOR2 PRMT7 POLD1 MARCKSL1 AAMP MRPS33 MCM5 TDP1 PDIA4 LSM4 U2AF2 CCNA2 ADM PRIM1 PRDM10 CDC42BPA ECHS1 GTF3C5 NME7 ETHE1 PFDN4 TP53	up	**
REACTOME_METABOLISM_OF_NUCLEOTIDES	0.0041284	0.0370647	0.4070179	0.3897502	1.623120	89	ENTPD2 AK4 GMPS TYMS UMPS XDH DPYS AK8 NME1 DNPH1 NUDT1 RRM2 NT5C1B ENTPD6 DCTPP1 CAD ENTPD5 UCK2 ATIC AK7 UCKL1 UPP2 DHODH TK1 DTYMK NUDT16 NT5M PFAS ENTPD8 ENTPD3 LHPP NME4 ENTPD7 GMPR2 PAICS TK2 DGUOK ADSL DPYD APRT TYMP AK9	up	*
GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP	0.0003838	0.0059819	0.4984931	0.3592003	1.623028	172	TFPI2 SCIN TICRR CCDC34 MPP6 NDC80 DEPDC1 GINS1 CDCA2 IQGAP3 PTTG1 CDC6 ARHGAP33 DTL CCT2 NME1 WDR62 C9orf116 RND2 MCM7 RAD54L KIF11 POLR3C THYN1 CKAP2L RAD51AP1 SPC24 PKMYT1 PSRC1 KNSTRN CKS1B NCAPG2 CDKN2C CENPH SCTR SEC61G PEG10 SPAG5 CENPP CCNE1 DLGAP5 CHTF18 ESCO2 GAS2	up	**
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0	0.0024802	0.0252580	0.4317077	-0.3571945	-1.622460	70	SASH1 HSD17B11 BACH1 DDX6 ALAS1 PLA2G7 LIFR FOXP1 ADRB2 CYP4V2 MAP1LC3B ITIH5 NR1D2 TEF RECK CREBRF RHOQ PNPLA2 RIN2 VAMP4 AOX1 GABARAPL1 GEM SESN1 CEBPD	down	*
GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN	0.0003154	0.0050878	0.4984931	-0.3058740	-1.622201	182	LRRFIP1 EGR2 GTF2E2 RBM14 S1PR1 BCL2A1 HPS5 ATP2B1 HBEGF PAQR3 EIF4E IL18R1 NFE2L2 NDEL1 SRGN CD58 MAP2K3 ADO PER2 NFKB1 ATF3 CCL4 SH2D2A PPP2CA PNO1 GABPA CYCS RHOG TMEM251 IPO7 IFRD1 SP3 NOL7 ACSL1 BAZ2B TEX30 DUSP5 GNAI1 ATP6V1A NAB1 GNG5 CD81 UTP3 PGGT1B MBNL1 GEM ANKLE2 IL18RAP WDR1 CDC42EP3 RIPK2 UBE2D1 TRAF1 STK4 ZNF165 PSMD9 NUP160 FEZ2 ARFGAP3 EIF4G2 SNRPG ICOS WDR47 GABPB1 KLHL9 CFLAR GTF2H1 IVNS1ABP PNP RANBP2 TNFRSF1B GNL2 SUCLA2 KLRG1 CYTIP PSMD14 TRPC6 EZR AGO2 PGAP1 CD47 PTPN22 SACS SEC62	down	**
RUAN_RESPONSE_TO_TNF_DN	0.0035178	0.0330771	0.4317077	-0.3580486	-1.621591	67	GPD1 PPARG LPL AATK QKI ALAS1 HIPK3 FABP5 CFD SORBS1 AOC3 CEBPA ARL4A SELENBP1 TPP2 ACSL1 COL15A1 TOB1 RGS2 ESYT1 ACADM	down	*
GO_CAVEOLA	0.0042497	0.0379275	0.4070179	-0.3572469	-1.621448	69	HMOX1 DLC1 ADTRP EMP2 CAV1 CORO1C CDH13 BMPR2 ADCYAP1R1 CBL TGFBR2 SCN5A CAV2 KCNMA1 PTGIS HCK KCNA5 ADRA1A CLN3 EHD2	down	*
BILD_MYC_ONCOGENIC_SIGNATURE	0.0006830	0.0094694	0.4772708	0.3549165	1.621364	181	SORD C12orf66 METTL1 CDK4 FGF11 FLAD1 KCNQ5 CDCA8 XPO5 EPS8L1 OSBP2 C19orf48 NLE1 LAMC2 SLC29A2 TTLL12 AIMP2 TGM1 MST1R SLITRK6 PHB ALG3 PES1 CCDC78 ATIC SLC12A8 NOP2 LINC00173 PA2G4 FAM86C1 COL1A1 DHODH NGFR PLEKHG3 MYBBP1A GEMIN5 AGPAT5 ANAPC1 CCDC137 DHRS1 LSG1 DGKA ERBB3 RRP9 GPATCH4 NOL6 ABCC3 ERVMER34-1 UTP20 FCHSD1 SSH3 RABEPK STMN3 EXOSC5 FARSA CYTH2 FARSB PFKM RNF213 CGN PAICS GOLGA2 FGFBP1 ADAM8 PDP1 SFXN4 KHNYN	up	**
SRF_Q4	0.0001332	0.0024488	0.5188481	-0.3049218	-1.621263	175	PPARG EGR2 CITED2 IER2 JPH2 KCNK3 CSRP1 EMILIN2 FOXP1 KLF6 NR4A1 MCL1 CNN1 ROCK2 TNNC1 TRIM46 YBX3 VASP THBS1 MYO1B NPR3 KCNMB1 DSTN ACTG2 MYH11 SRF TMOD1 PRDM11 SGK1 PODN DDX17 JUNB RHOJ LYRM1 HERC1 RASSF2 COL23A1 IP6K1 FOS KRTCAP2 FOSB DGKG SORT1 AKIRIN2 TGIF1 DUSP5 TGFB1I1 MRGPRF TAGLN MBNL1 PDLIM5 VGF DIXDC1 PTCH1 ACTB G3BP2 EDN1 RSU1 EGR1 ARHGEF17 CFL2 CDKN1B DUSP6 SVIL ADAMTSL1 DCUN1D3	down	**
GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN	0.0009910	0.0126266	0.4550599	0.3585922	1.621259	174	EGLN3 ELOVL6 CENPF PHGDH TTK CDCA2 AP1S1 PTTG1 GPI ACOT8 CCNB2 STC2 MCM4 SPPL2B RUVBL2 CISD1 RND2 KNTC1 FANCA MSX1 CLSPN RAD54L CMBL PYCR2 CKAP2L CBY1 DCTPP1 MTG1 UQCR11 THOP1 KCNE3 TTLL9 UNG CMTR1 DNA2 FAM98C SAPCD2 AARSD1 MRPL52 ESCO2 IGHM LRWD1 PRMT7 COX10 TIMM13 MCM5 CAPRIN2 NDUFS7 HAUS4 NEFH LHPP CBR1 B9D1 MSH2 DCPS CCDC88B UQCRQ CLEC11A PNKP CENPE MPG UBE2C C12orf10 TEX9 COPE OVGP1 MAN2C1 RAB40C SIGIRR PPARGC1B RPL36 PSMB10 MRPL2 LZTS2	up	*
GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP	0.0001748	0.0030606	0.5188481	-0.3046247	-1.621258	177	WTIP ARHGAP31 SWAP70 ADCY4 HSD17B11 EMCN LY86 INPP5K CALCRL ELMO1 FAM49A TXNIP TMEM204 MAP3K8 GATA3 PPP1R13B KANK2 TFEC HERC3 MTHFR CD37 TIPARP EFCAB14 FUT7 ITIH5 PDE8A CCL4 TLR4 PNRC1 RECK TM6SF1 WFS1 UBASH3B NCKAP1L MYLIP FMNL2 CHDH RGS18 MITF STAT4 OSBPL9 IRF8 DOCK8 RNF24 CDK14 RRAS	down	**
GSE3039_B2_VS_B1_BCELL_DN	0.0008188	0.0108702	0.4772708	0.3597756	1.620453	159	SCIN CEP89 TICRR BUB1B CCDC127 ECE2 METTL1 IQGAP3 POLE BAMBI CDCA8 GPI COQ3 RANBP1 RSPH1 IGF2BP2 HOMER3 KIF2C MAD1L1 CLSPN ICA1 AKAP1 RAD54L ANKRD13B CHEK1 DCTPP1 SPC24 TST CNOT3 ALDOA PSRC1 ASF1B GOT2 SLC16A13 HMGXB3 RAPGEF5 ILF2 CCNE1 SCLY SNRPA C19orf12 TMEM237 KCNC3 MLEC CENPM CENPT CLUH SLC1A5 SH3PXD2B CKAP4 PPP6R2 CPT1C SMPD4 TP53 FRMD6 APEX1 NOMO1 E2F7 NDUFB7	up	*
MORF_FBL	0.0016655	0.0186190	0.4550599	0.3731306	1.620451	123	COA1 AURKB GPI MCM2 EIF3B CCT2 NME1 RUVBL2 NUDT1 EEF1E1 CBX3 MCM7 AHCY FBL ANAPC5 HDGF SSBP1 CCT3 KXD1 SNRPE ILF2 UQCRFS1 SNRPA JTB CCT7 PRMT1 TMEM147 LSM7 POLR2I LSM4 SF3A2 EIF3K NDUFV1 DOCK3 BANF1 SNRPD2 PDAP1 MRPL9 TBL3 LYPLA1 CLNS1A DRG1 CS HNRNPAB SRSF9 PPP2R1A DDX49 FIBP XRCC6 PSMD8 HNRNPA1 PPM1G BUB3 ATXN10 HNRNPUL1 TRIM28 TARDBP PCNA NCL SNRPB PARK7 CDC123 UBA2 YWHAQ BTF3	up	*
GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN	0.0001748	0.0030606	0.5188481	-0.3044410	-1.620280	177	CD300LF IL1A SOWAHC F2RL3 LYVE1 HCAR2 BACH1 MYD88 FGR NDUFAF1 PLXNA2 ITGA5 HDC SERPINB9 TOR1AIP1 AKT3 TXN TUBB6 TIPARP IL10 MEFV BST1 THBS1 SOCS2 CLIC4 CDKN1A SELL CCL4 CCND2 MAFF PROCR ETF1 IL6 DDHD1 PNO1 SOCS3 JUNB ATP11A RHOJ IRF8 OGFRL1 CST7 TMEM192 FOS STXBP3 FPR2 BRI3 ADPGK IL18 ADAMTS4 RIPK2 TMEM184B FNBP4	down	**
ZHENG_BOUND_BY_FOXP3	0.0000003	0.0000141	0.6749629	-0.2756066	-1.619986	440	PEBP4 MS4A7 DENND5A LRRC8C LTA4H GPR65 RAPGEF2 FYN CD44 SAMHD1 CITED2 S1PR1 ELMO1 GIMAP6 ZBTB2 TGFBR2 TRIB1 ANXA1 ATP2B1 TRA2B LATS2 RAP1A MAP3K8 FOXP1 KLF6 PAG1 LCP1 GATA3 RB1 SPTBN1 HERC3 PPP3CC FLI1 KDSR GLDN DENND6A ITM2B LEPROTL1 STK17B SOCS2 PTPRC SELL SELP AXL ACTR3 PTGER3 CD53 ELK3 ARL4A PPP2R5C IL7R UBASH3B NUS1 TBC1D4 FAM76B CNOT6L VWF VCPKMT ZDHHC20 STK24 TBC1D5 ELF1 CREM PHTF2 NSMAF NEK7 RAB8B UTRN ETV3 PSMA1 LRCH1 STAT4 ZFP91 NSMCE2 ETS1 HK3 MAP4K4 ARHGEF10 IFNGR1 JAK1 PTGER4 CCR7 UBAC2 GPR183 PTGER2 MALT1 COBLL1 TPP2 GTDC1 RGS13 NDUFV2 CELF2 SNX9 GPRIN3 PELI1 AGPS KLF2 CDK17 HIVEP2 ECI2 ZNF175 ZFAND6 GIMAP1 NUP153 MRPL39 ENPP6 ZBTB1 TEC ZC3H12D UTP3 SBSPON MACF1 GPR18 PDE4B MBNL1 NR2E3 RBL2 LDLRAD4 SESN1 C3orf38 EXOC2 CHURC1 PARM1 MS4A4A PIP4K2A SIK3 ZBTB25 SP100 SSH2 JMJD1C DOCK10 B3GNT2 CYTH1 AIM2 SAMSN1 C21orf91 TLK1 GIMAP4 EVI5 IRF2 CDKN1B DUSP6 NR4A2 CX3CR1 PRKCH ICOS MAMDC2 KBTBD11 PIK3CG AQR CD69 PIAS2 SNX14 RCSD1 POLI MAN1A1 RCBTB2 MAP3K1 SLC23A2 TRAT1 NR5A2 ITGA6 NR4A3 CD226 JARID2 IRF4 AKAP13 TTC39B NFKBIZ ANKH C15orf48 ANKRD44 ADAM19 FAM107B HBS1L FEM1C CYTIP FLT3 TMEM71 SLAMF1 ITPR2 ANKRD28 AGO2 PGAP1 FASLG PTPN22 TMEM64	down	***
GO_PLASMA_MEMBRANE_BOUNDED_CELL_PROJECTION_CYTOPLASM	0.0013546	0.0160830	0.4550599	0.3595574	1.619872	165	KIF1A GRIK2 DNAH2 RPGRIP1L AP3B2 CENPF UCHL1 SPAG17 DNAH3 AK8 DNAI1 ARMC4 BBS1 SPAG16 KIF3B HYDIN WDR78 CCDC114 DCDC2 BLOC1S1 WDR66 DNAH8 IFT172 GAS8 DNAH11 TULP3 CCDC40 DRC1 KIF5A AP3D1 KIF19 SPAG6 LCA5 DNAH5 RANGAP1 SPEF1 BBS5 SPG7 DNAH7 MNS1 CCDC151 HIP1R TRAF3IP1 DNAJB13 WDR34 TTLL3 EFHC1 AP3M2 RPGRIP1 DNAI2 WDR35 DYNC2H1 NEK4 RSPH4A SYBU DNAH1 TRAK1 WLS MAPK8IP3 DTNBP1	up	*
GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION	0.0000051	0.0001590	0.6105269	0.3326370	1.619456	388	HMGA2 TRIP13 CEP72 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF PAGR1 STOX1 NDC80 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 DBF4B KIF14 ANLN CEP70 PLK1 AURKB ESPL1 CDC6 TPX2 TFDP2 CDC25A ORC1 DTL ZFYVE19 CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 CEP250 CASP2 HMMR BTRC SMARCD3 KNTC1 BUB1 AURKA ODF2 SFI1 TPR MAD1L1 CLSPN CDCA5 PRKDC CDC25C SOX4 EGFR TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 BLM PML CNOT3 ERCC2 STXBP4 CDKN2C ANAPC5 CTDSP2 CDK1 CENPJ RFWD3 E2F1 PSMB5 ANAPC7 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 FGFR1OP CEP63 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 NINL PSME2 MTA3 FZR1 ANAPC1 PSMD2 ATAD5 CDC7 CKAP5 PSMB3 CDC20 CHMP4C WNT10B CDK5RAP2 PRMT1 UIMC1 HAUS6 TFAP4	up	***
GO_CIRCULATORY_SYSTEM_DEVELOPMENT	0.0000000	0.0000000	0.8753251	-0.2574712	-1.618818	901	SMAD6 ANGPT4 RBP4 EPAS1 SEMA6A EREG HSPB7 RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK PDLIM2 DLC1 TAL1 PECAM1 RASIP1 CCM2L PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 WNT4 EMP2 RAPGEF2 BMPER RAMP2 PTPRB BMP2 SIK1 CDH5 ENG LYL1 ARHGEF15 FOLR1 ECSCR SOX17 CAV1 CITED2 FOSL1 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 PRKAR1A MEF2A CDC42 MIR27B TGFBR3 TGFBR2 NFATC3 SCN5A HSPG2 HEG1 RHOA PDE2A KCNAB1 APOD JPH2 ANXA1 TBX2 MIR146A MMRN2 PTPRM LMNA RAP1A TMEM204 ITGA5 CLEC14A HSPB1 LUZP1 FZD4 ANPEP GATA3 NR4A1 JAM3 RB1 RGCC NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A HNRNPU SPI1 TCAP TCF7L2 PDGFA FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 MMP21 ROCK2 AMOTL1 SNAI1 NRARP TNNC1 FOXO1 TBX4 EPOR TNFSF12 TSPAN12 KLF4 REST ID3 ROCK1 ZFAND5 GAA THBS1 ADAMTS9 CLDN5 CLIC4 SEC24B FMNL3 CDKN1A PDE3B ITGAX EPGN HPSE ID2 MIR24-2 RECK PIK3C2A ELK3 SMAD7 ZMPSTE24 ADIPOR2 MBD2 TBX5 SH2D2A MYH11 NUS1 PTGIS DCHS1 HES1 MIR17HG PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ SLC8A1 FLT1 IL6 WASF2 PKNOX1 CD160 PSEN1 SOCS3 NDNF JUN NOTCH1 ETS1 ADRA1A JUNB EPC1 JAK1 RHOJ RAPGEF1 ACKR3 CREB1 NPR1 TBX21 NDST1 NDUFV2 MCAM CD34 POGLUT1 RRAS KLF2 CACYBP GJA4 PKD2 TREX1 WNT11 SYPL2 SAV1 TGFB1 VAV3 ISM1 JMJD6 MIR23A PDLIM1 MIA3 PIM1 COL15A1 SOD2 MEIS1 MYOCD GATA6 GNA13 ACTN2 RGS2 LTBP1 KAT2B ADAM10 PRICKLE4 RXRA SMAD2 FGF2 IL18 PDLIM5 FKBP1A VASH1 EGFL7 EPN2 ARRB2 OSR1 SETDB2 SEMA4A RTN4 CXCR4 TAB2 PTCH1 SP100 ACACB EPHA2 PARVA GLUL STK4 RAPGEF3 KIT EDN1 SCUBE1 ETV2 FOXJ2 PTEN SYNPO2L FGFR1 RORA MIR548C LDLR NRP2 NRG1 NAA15 ZFPM2	down	***
GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_DN	0.0038253	0.0350937	0.4317077	0.3903208	1.618496	86	RIBC2 SLC5A5 SPATA24 PPP1R1B PAX9 DCST1 MIR205HG CHST4 MKS1 PCLO CMYA5 TMEM132D C2orf81 SLC34A3 PCDHGB7 WDR72 C11orf16 SMYD5 EGFR LINC00265 AFAP1L2 KRT18	up	*
GO_SPECIFIC_GRANULE	0.0003326	0.0053100	0.4984931	-0.3208399	-1.618381	131	SLPI OLR1 HVCN1 RAB44 CLEC12A PTPRB OSCAR CHIT1 CD36 SLC44A2 CD33 RAP1A PTX3 STOM LAIR1 CD93 LAMTOR3 BST1 PLAUR STX3 ATP6V1D CTSD TMBIM1 ERP44 NFKB1 HPSE CD53 DEGS1 ANXA3 CMTM6 HGSNAT SNAP23 CTSZ ATP11A ALDH3B1 TIMP2 STXBP3 FPR2 TSPAN14 GPR84 ORM2 ADAM10	down	**
GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN	0.0002062	0.0035226	0.5188481	-0.3089556	-1.617647	166	CD55 LMO2 SAMHD1 MYADM CITED2 GGA2 PDE2A B3GNT5 PICALM KLF6 LCP1 PPP3CA FLI1 AHNAK FOXO1 RRM2B ID3 VIM SELL LBH ADD1 LMBRD1 AFF3 NCOA1 EMP3 FRY WASF2 SGK1 STAT4 SH3BP5 SNX29 MAP4K4 JAK1 SNX2 GMFG PXK SNX9 KLF2 BIN2 TGFB1 CC2D2B TEC LGALS3 CCR6 CXCR4 LRP12 TBC1D1 BRWD1 RNF38 CCND3 IQGAP1 GIMAP4 IRF2 ARHGEF18 ATP6V0A1 EGR1 CTSH TUBA1A ATP1B1 CSNK1G3 CD69 RAD21 TRIM25 SH3BP2 TNFRSF13C FCHSD2	down	**
GSE20715_0H_VS_48H_OZONE_LUNG_UP	0.0002921	0.0047791	0.4984931	-0.3074132	-1.617543	168	CD52 PDLIM2 PTPRE FIG4 LYL1 LY86 LMO2 INPP5K NEDD4L PLEKHA1 YPEL5 SLCO2A1 TLCD2 SLC44A2 CLEC14A ACOT2 SRGN CD37 FBXO8 EVI2B SRSF5 PTPRO PTPRC SLC6A6 SEC31A ARHGDIB ACTR2 RPS6KA2 MYLIP MYO1C HMBOX1 RAB31 SNX2 DAPK2 IRF8 EHD2 GIMAP1 SORT1 ZNF521 SERPINB1 IFNAR1 CD81 DECR1 RGS2 PCCA ELF5 ARAP2 SESN1 CXCR4 PTCH1 CD19 LIMCH1 EMC3 GIMAP4 CNN2 CNR2 FKBP1B PXMP4	down	**
GO_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	0.0009762	0.0124878	0.4772708	-0.3199707	-1.617482	122	ACP5 SPN LPL GAS6 IL23A CD36 TNFRSF8 CD33 CLEC7A HSPB1 FOXP1 SIRPA ARHGEF2 IL10 PTAFR THBS1 LY96 CCL3 PTPRC AXL TLR4 FCER1G PSEN1 TYROBP IFNGR1 PIK3R1 CD34 AZI2 TREX1 CD86 ORM2 GPR18 TSPO SYT11 ARRB2 RIPK2 HAVCR2 CYBA C5AR2 CX3CR1 TREM2 ZFP36 TBC1D23 WNT5A BCL10 AKAP12 HMGB1	down	*
GO_MEIOTIC_CELL_CYCLE	0.0008057	0.0107468	0.4772708	0.3584788	1.616789	169	TRIP13 BUB1B NEK2 MND1 TTK SLC26A8 ASPM PLK1 NUF2 PTTG1 ESPL1 FIGNL1 RBBP8 RAD54B CDC25A XRCC2 TDRKH NCAPD2 RSPH1 EXO1 STAG3 FBXO43 BUB1 FANCA MSX2 TOP2A AURKA EME1 REC8 SYCP2 MSX1 NSUN2 RAD54L FANCD2 HORMAD1 CDC25C EME2 BRIP1 SUN1 METTL3 CCNE1 TUBG1 MNS1 RAD51D FZR1 SLX4 RAD50 ANKRD31 KLHDC3 MEI1 CDC20 TUBG2 RPA1 FANCM	up	*
REACTOME_SIGNALING_BY_NTRKS	0.0015102	0.0173371	0.4550599	-0.3200894	-1.616608	123	BDNF LYL1 FYN EGR2 FOSL1 ADCYAP1R1 MEF2A TRIB1 RHOA RAP1A CRK DUSP3 PTPRO REST ID3 RIT1 ID2 ARC SRF RPS6KA2 ID4 PPP2CA SGK1 JUNB RAPGEF1 PIK3R1 GRB2 CREB1 RPS6KA1 RALB FOS FOSB PPP2CB NAB1 IRS2 JUND VGF TIAM1 ADORA2A DUSP7 EGR1 DUSP6 ATF2 MAPK1 YWHAB KIDINS220 EP300 MEF2D	down	*
GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_DN	0.0008578	0.0113062	0.4772708	0.3536879	1.616215	182	FOXM1 CDC45 POLQ GMPS ESPL1 MCM4 SPINT2 EIF3B DTL MYL6B CCT2 SPDL1 MELK EXO1 MKI67 KIF15 KNTC1 CCT5 PUS7 ODF2 POLD2 COASY RBM28 RAD54L SLC35G2 KDELR2 MAD2L1 RAB13 BLM IDH2 TFCP2 EXOSC2 TNFRSF21 CCT3 POLR3K MCAT MRPL17 MRPS12 LAPTM4B CCNE1 DPP3 PSMA5 TACC3 PSME2 MRPL11 CASP7 AGPAT5 CCT7 CDC7 RAD50 SUPT16H NPRL3 LRRC59 FAM136A BCL2L1	up	*
GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN	0.0004611	0.0068894	0.4984931	0.3576721	1.616123	172	CEP72 BDH1 CCDC34 SORD NIPSNAP1 TRIB3 RBBP8 UHRF1 CDC25A APOL2 SHMT2 DCTN2 CISD1 STAP2 MCM7 PKM ORC6 KHK IDH2 NSF MRPL37 POLE2 DTD1 GMNN UNG MRPL17 KIF2A LRRC42 SF3B3 MAD2L2 RECQL4 UNC45A POLR2H VBP1 MOV10 GALK2 PSMA5 SNRPA LMNB2 TUBA3D MRPL52 TMEM237 MAGOHB RAB24 ANKRD6 FAF1 FBXO22 TMUB1 PIGX GLO1 LRP11 CCNA2 RFC5 GBP2 PAXIP1 FRMD6 GPX7 NAT10 WIPI1 CORO1B PRKAG1 TFB1M	up	**
GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN	0.0001209	0.0022620	0.5384341	-0.3039072	-1.616029	176	SLC31A2 SIDT2 TUBD1 SGK3 ADPRH CLEC12A TXNL1 NEDD9 MTF1 ZNF410 ABHD6 CRK TCF7L2 SETD3 CD58 GMEB1 CASP1 RNFT1 VRK2 DPH3 CYP20A1 TLR4 ZMPSTE24 SMNDC1 FMNL2 DDX60L CRNKL1 DESI2 PI4K2B NAA30 ZCCHC9 BLOC1S6 GRSF1 SIGLEC1 CD164 AZI2 MSMO1 ZCCHC10 IFNAR1 THAP9 CCR1 PHF11 ACYP2 POLK ME2 BMP2K SLC31A1 NT5C2 METTL21A CYP2U1 HAVCR2 TMX2 CTSC FNIP2 HEBP1 CNOT8 SCLT1 PPP2R3C DUSP6 ZNF106 SNW1 IFIT5 LAMP3 SNX14 UNC50 C11orf54 BCL10 NMI CCNYL1 NTAN1	down	**
MIR8084	0.0001589	0.0028269	0.5188481	-0.3001980	-1.615521	197	MGAT3 FOXF1 ABHD5 DLC1 OSBPL1A TRPC3 BAG4 QKI WBP4 TET2 SCN5A ZEB2 DNAJB14 PTS TRA2B RAP1A HIPK3 AKT3 ZEB1 GPM6A PTPN12 MSR1 PTPN21 SETD9 RECK DUSP1 ELK3 RSL24D1 LIN7A ZNF330 MOB4 FMNL2 JUN NOTCH1 HMBOX1 SLC14A1 ATP11A OSTM1 FOXN2 PI4K2B FSD1L SLC10A7 OGFRL1 EPC2 SPRY4 CDK17 PSMD12 SRSF6 SLC35F1 CCDC152 PDS5B SLC24A1 ACYP2 PDE4B CTTNBP2NL XKR8 ING2 SCAI B3GNT2 CECR2 DNAJB9 FAM126B MMD RORA FAM13C UBE2V1 CFL2 ATP11B NR4A2 BDKRB2 PRTG IL5 EP300 CRIPT MAP3K1 NR5A2 NKD1 RAB11FIP2 SIRT1	down	**
GTGCAAT_MIR25_MIR32_MIR92_MIR363_MIR367	0.0000186	0.0004737	0.5756103	-0.2907952	-1.615317	266	SMAD6 GATA2 CPEB2 ATXN3 SIK1 INSIG1 ARRDC4 EGR2 BMPR2 PLEKHA1 S1PR1 P2RY13 DSCAML1 OTUD4 ZEB2 EDEM1 NFIX LATS2 ITGA5 BTG2 NLK LUZP1 REV3L GPBP1L1 MCL1 RAB14 MOAP1 PTPRO KLF4 CEBPA SOCS5 MYO1B PER2 DOCK9 TEF USP44 SMAD7 PAFAH1B1 SNN LIN54 SERTAD2 MYLIP FRY PHTF2 NSMAF RNF141 APPL1 PIKFYVE NECAP1 CPEB4 CNTN4 FOXN2 PTGER4 KLHL18 PRKCE CREB1 MORC3 PDZD2 TRAK2 CXCL5 GFPT2 KLF2 PIK3AP1 TGIF1 PDS5B BAZ2B CBFA2T3 TOB1 NPTN GATA6 KAT2B ADAM10 POLK PHLPP2 PITPNA CDKN1C TOB2 G3BP2 TMEM184B FNBP4 ZDHHC5 RNF38 TMEM87A LYST DNAJB9 FAM126B FAM13B KALRN ARHGEF17 LHFPL2 SLC38A2 ADAMTSL3 CD69 C6orf62 UBE2W FAM160B1 GOLGA8B SGPP1 RAD21 PIP5K1C MEF2D ROBO2 FNIP1 NR4A3 CCNC HIVEP1	down	***
GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN	0.0001032	0.0019837	0.5384341	-0.3060370	-1.614709	171	CXCL3 IL1A SOWAHC ARRDC4 MOB1B EDEM1 RBM7 MALAT1 CYB5A PARVG CAV2 STOM SLAIN2 TNS1 ITSN2 ARRB1 MTMR6 PPT1 ZADH2 TMED5 FBXL3 NFKB1 MARVELD1 GCA N4BP2L1 MPC1 RUFY3 MEDAG GLB1 SPIN1 ELF1 PHTF2 PHACTR2 MTMR14 SH3BP5 ENPP4 HERC1 MSANTD2 HOMER1 DEDD CELF2 TCF4 CNOT7 HINT3 GTF2B GEM PDLIM5 NBN B3GALNT1 RIPK2 TMEM184B FNBP4 STK4 CYTH1 ITCH CBX7 MRPS28 SERPINE1 CLIP1 ENDOD1 DYNC1I2 CHAC2 MPV17 RCSD1 IRF1 TRIM25 CCPG1 CASP3 ANKRD44 IVNS1ABP ZC3H7A CAAP1 SPAG7 HBS1L IL10RA	down	**
GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN	0.0002709	0.0044750	0.4984931	-0.3081996	-1.614585	157	ABHD5 SLC12A6 PLEKHF2 SLC25A30 PPM1D TXNIP BTG2 RANBP9 PARVG ABCG1 CLK1 ITSN2 TFRC CCNI TLE4 CDKN1A ATF3 ARHGAP9 CLK4 N4BP2L1 CLIP4 C16orf54 BTG1 AXDND1 PPIL4 SLC25A25 PHTF2 UTRN HCST DOCK8 ZNF597 MEAF6 RHOQ CDK17 ZFAND6 DUSP5 ZBTB11 C16orf72 DOK2 ADAM10 HELZ JUND TRAC PIP4K2A ESYT1 MEGF9 MEX3C CREBBP RNF38 FOXJ2 SKI LYST MMD	down	**
GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP	0.0002360	0.0039569	0.5188481	-0.3075839	-1.614289	167	DNAH17 SEMA6A INSIG1 ST3GAL6 CORO1C RPL23AP53 NR3C1 IL1RN IER2 LRRFIP2 SH2B3 CHMP1B ANXA5 EIF4E BTG3 UBE2D3 ZNF365 MAP2K3 MOAP1 SRSF5 DNTTIP2 RABGGTB TOPORS PRKRA DCP1A FLT1 IL6 SOCS3 NXF1 GABPA ELP5 JUNB CSTA PPP1R15A FBXO11 HUNK DLEU2 TSPYL1 GPRC5A AGFG1 SLC3A2 AZI2 USP7 MAPK8 TFEB OSGIN1 PIK3C3 ZNF143 TAB2 G3BP2 RBM48 SKI TMEM87A AIM2 ITCH SFPQ MED17 PPP1CB	down	**
MIR421	0.0003828	0.0059702	0.4984931	-0.3132577	-1.614240	144	ZC3H12C RDX TRPC3 SOX17 CALCRL QKI VAPA SEMA6D ASAP1 FAM122A CLEC1A ACSL3 RUNX1T1 KLF11 MGAT4A HOPX MBD2 ZNF706 TBC1D4 CALM2 SLC25A3 DDX60L PRDM11 DNAJC27 PHTF2 ETS1 JPH1 SP3 SLC10A7 BLOC1S6 TTBK2 ATG2B DCAF5 TESK2 ZBTB11 TLDC2 ATAD2B ARPP19 LDLRAD4 SRSF10 FAM126B RORA RSU1 CLOCK FAM8A1 KIAA2026 CTDSPL2 SGIP1 MPV17 CAPZA1 SRR FCHSD2 SREK1IP1 JARID2 ARGLU1 CASP3	down	**
GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN	0.0002107	0.0035798	0.5188481	-0.3032862	-1.614134	177	CXCL3 SCN4A MS4A7 TBX3 LPXN LY86 FUT1 MYD88 PRPF38A GNPTAB ZBTB2 PDCL ARHGAP10 RRAGC COX18 KLF6 SERPINB9 TIPARP IL10 MPEG1 ITM2B C9orf72 CCND2 WFS1 SLC6A6 KBTBD4 IL7R SPRYD7 SMNDC1 CMTM6 HCK PROCR USP25 PKIG SGK1 STAT4 SH3BP5 ATP11A PRKCE GRASP MORC3 OGFRL1 CDK14 TMEM128 SPOP EPHA3 STXBP3 NR2C1 CD86 GNB4 RNF2 TAB2 NSUN4 FNBP4 TIMP3 KLRK1 CYTH1 SMAD4 IRF2 AFTPH SPSB1 KLF15	down	**
GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP	0.0008661	0.0113916	0.4772708	0.3551329	1.614100	178	PPM1H MDM1 BDH1 PAGR1 NPY6R HILPDA ECT2 COX11 MPPED2 ZNF74 HLTF HOMER3 MCM7 ABCC5 PASK CHAF1B RNFT2 TRMT61B CBY1 KHK C2CD3 TRPV4 GOLGA8A VPS72 STK11 POLR2H SNRNP25 NFS1 ATP6V0E2 LRRC8D JTB OLFML2B GALNT7 TNK1 DGKA RPA1 MCM6 MCM5 TBC1D16 LRIG1 KATNB1 CREB3L2 POLR3E PRKD2 NT5DC2 UNC119B SPSB3 MSH2 GTF3C2 RFC5 USP39 NDUFA8 CDK5 SYNRG SEPHS1 FGFBP1 PPP2R5D ZER1 PARP2 ESM1 RCN2 SHQ1 PCNT PARL RWDD2B TMPO NCKIPSD STXBP1 PCBP4 HDAC3 MIEF1 NINJ2 TTC3 GRAMD4 HMBS NSUN5P1	up	*
SASAKI_ADULT_T_CELL_LEUKEMIA	0.0008896	0.0116220	0.4772708	0.3614580	1.613907	152	FOXM1 TFAP2A BUB1B CCNB1 CENPF PTPRN2 KIF14 PLK1 PTTG1 ACOT8 TPX2 CCNB2 TYMS ZWINT MYL6B NME1 KCNN4 MKI67 TOP2A KIF2C MSX1 KIF11 MCM3 ETFA TFCP2 PARP1 TMED3 MRPS12 TRAPPC12 ARNT2 POLR2H VBP1 DLGAP5 GALK2 TK1 HDAC1 TP53TG1 SAP30 FHL2 CDK13 PLD1 RPA1 MED24 LPCAT4	up	*
GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP	0.0004534	0.0068056	0.4984931	-0.3179802	-1.613437	139	KLF13 EGR2 RASAL2 KIAA1109 STX11 TRIB1 SLC44A2 MAP3K8 NR4A1 UBE2D3 ADAMTSL4 MEFV FAM124B SNORA30 NFKB1 PER1 CPT1A PTH1R ETV3 ARL5B DDX17 PPP1R15A PTGER4 GPR183 CREB1 REL DEDD MCAM FOS GSAP TGIF1 NAB1 PDCD1 TAGAP GPR18 DBNDD2 ICAM1 ARAP2 YAF2 SSH2 SDAD1 NFKBIA CTSC TTC19 SAMSN1 VPS13D EGR1 FPR1 NDFIP1 CSNK1G3 CD69	down	**
MORF_PPP5C	0.0053732	0.0451257	0.4070179	0.3909515	1.613291	81	FANCI BRCA1 RBBP8 CCNF WDR62 BPHL ERAL1 FNTB FDXR PPP5C ERCC2 MEA1 OARD1 TTI1 ZNF500 FANCG CDK13 PLEKHB1 SH2B1 EP400 CPSF4 CYP4F12 NFRKB RFC5 PAXIP1 CHD3 POP4 NMT1 SIGMAR1 ILVBL GRIP2 KIAA0586	up	*
E2F4DP1_01	0.0004540	0.0068104	0.4984931	0.3502331	1.613269	196	ONECUT1 GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 SEZ6 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 LIG1 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 SASS6 MDGA1 OLFML3 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2	up	**
GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP	0.0002456	0.0040956	0.4984931	-0.3072671	-1.612626	167	CXCL3 SCN4A SECISBP2L CD55 PTPRE ELF2 DNASE1L3 ZEB2 SH2B3 UBL3 EIF1 SERINC1 ABCG1 GLS HLX TRAF6 SPTBN1 CLK1 GPM6A FLI1 PTPN12 MTMR6 SRSF5 YBX3 KLF7 DOCK9 CXCL2 CTBS SMAD7 ADIPOR2 CRIM1 HCK RPS6KA2 MOB4 MYO1C PSEN1 NEK7 ZNF548 MAGI2 APBB2 STX7 ENPP4 RPS6KA1 AGFG1 BAZ2B VAMP4 MIA3 SLC24A1 HBP1 SBSPON N4BP2L2 CEBPD CREBBP DAPK1 RASSF8 LYST DNAJB9 CYTH1 IL16 RNF13 EVI5 ABI1 SH3GLB1 RB1CC1 FAM8A1 ZFP36	down	**
MIR513B_5P	0.0000228	0.0005597	0.5756103	-0.2938660	-1.612532	234	WEE1 DLC1 TBX3 GATA2 KL RCOR1 BDNF CCDC36 VAPA TET2 SCN5A RHOA ZEB2 MED26 SPRY2 HNRNPU TCF7L2 ZYG11B EIF1B CWC22 AGO4 PRDM16 KCNMA1 PKD1L1 MED6 GAPVD1 MGAT4A GPR85 USP44 ZBTB43 SPRYD7 C2orf69 BTG1 USP25 METAP1 RYBP EBF2 NEK7 GABPA SNX2 EEA1 SNURF SLC10A7 APOL4 TMEM192 AGFG1 PKIA TRAPPC10 SRSF4 PDS5B PDE12 GNB4 CLASP2 AMD1 HNRNPK TBCEL FAM126B SYNPO2L C1orf52 GIMAP4 ARFGAP3 DNAJA2 RABGEF1 IRF2 HAT1 FAM131B ADAMTSL1 ATF2 LHFPL2 SH3GLB1 FBXW2 SV2B LRRC2 GABPB1 MAN1A1 DR1 SNRPN WWTR1 CNTN1 CCNYL1 RNGTT CCPG1 PTGS2 IMPACT BMPR1A SLC18A2 IVNS1ABP CBLL1 CASQ1 PTPN14 FEM1C TNFRSF19 PIK3R3 ERBB4 RBM27 MTDH PPP1R14C ABCE1 TMEM64	down	***
MIR4418	0.0022027	0.0231021	0.4317077	-0.3205258	-1.612363	111	RTKN2 GFOD1 CORO1C CHRNE PICALM CAMTA1 GPM6A EIF1B DENND6A NES ZNF423 ZFAND5 MGAT4A GPR85 CCSER2 MPC1 AFF3 BTG1 SERTAD2 MED28 PPM1F AGFG1 KIAA0232 GALC ATAD2B INO80D FGF2 ATP9B G3BP2 FAM126B RHOT1 EHD4 SPOPL GPALPP1 PSIP1 CDC14A SLC25A38 RAB37 SLC38A2	down	*
GO_T_CELL_ACTIVATION_INVOLVED_IN_IMMUNE_RESPONSE	0.0038391	0.0351696	0.4317077	-0.3408430	-1.612307	84	SPN CD1C SLC11A1 IL23A ANXA1 FOXP1 HLX LCP1 IFNK GATA3 IL18R1 SOCS5 FCER1G SMAD7 CD80 IL6 PSEN1 PTGER4 GPR183 MALT1 RC3H1 TBX21 CD86 CD81 LGALS3 ICAM1 IL18 SEMA4A RIPK2 NLRP3 HAVCR2 RORA CLEC4E ITGAL HMGB1 TNFSF18 RC3H2 IRF4 NFKBIZ	down	*
GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN	0.0010218	0.0129169	0.4550599	0.3620852	1.611687	148	TICRR NUP107 NEK2 SRGAP3 SORD CDCA7 DGCR8 NUF2 EXOC3 MCM2 CDC25A PRC1 XDH DTL COPB2 ITGA2 MELK SDHA TOP2A KIF2C MPHOSPH9 GPSM2 MCM3 CHAF1B MAD2L1 AKT2 IPO9 NCAPG2 CBX5 RFWD3 PSAT1 NUP205 DNMT1 CCNE1 DLGAP5 TACC3 TRIM37 SSRP1 GALNT7 KIAA0100 MAN2A1 FBXO22 MCM6 WDR35 LANCL2 GINS3 LRRK1 MSH4 VDAC1 ANAPC2 VDAC3 PRPF3 SEPHS1 BPNT1 SF3B2 RCBTB1	up	*
GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP	0.0001423	0.0025779	0.5188481	-0.3011986	-1.611558	186	LPIN2 PNPLA6 GLIPR2 SPN ADCY9 RDX FYN PPP4R1 CCRL2 FLVCR2 IDI1 NR3C1 NEDD9 ARHGAP10 SH2B3 PTPRM C1orf21 TNIP3 ANXA5 SPIRE1 GATA3 PPP3CA AHNAK OSTF1 RMDN3 SIK2 EPS15 MBD2 PPP2R5C SH2D2A SLC6A6 PI4K2A PHACTR2 PRKCE IDS GTDC1 GFPT2 TIGIT RUNX3 NKG7 PEA15 ATXN1 GABARAPL1 STK40 PHF2 PDE4B RXRA ARAP2 CALHM2 SEMA4A SIK3 RBMS3 CCDC92 AIM2 NABP1 PMAIP1 PIEZO1 SLFN11 FNBP1	down	**
GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN	0.0002904	0.0047551	0.4984931	-0.3044791	-1.611464	169	LRRC8C GPR65 MIR22HG EGR2 FLVCR2 SLC15A3 LAMP1 IER2 AVPI1 GM2A EMILIN2 TMEM74B SERPINB9 SRGN BTG3 TIPARP CSRNP1 SYNPO LEPROTL1 GAA STX3 ATF3 JAM2 ARC PLEK SH2D2A UBASH3B DEGS1 CMTM6 ST6GALNAC6 RPS6KA2 RBPJ RAB8B HIC1 ATP6V0B PLK3 PPP1R15A PTGER4 EEA1 MALT1 CRYM TSSK6 PREX2 TBX21 RGS13 CLN3 CST7 AGFG1 SLC3A2 ATP6V0D1 TGFB1 SERPINB1 ATP6V0C TAGAP BRI3 CLCN6 CCR6	down	**
GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN	0.0008300	0.0110016	0.4772708	0.3528041	1.611150	184	ELOVL6 PDCD6 CCNB1 UCHL1 SLC2A1 TBRG4 BET1 RACGAP1 SFXN1 TYMS UMPS PRC1 CCT6A SHMT2 XPOT CCT2 RANBP1 KCNN4 CHAF1A MRPL15 EEF1E1 MCM7 RBM28 ERAL1 CHAF1B ACTL6A MAD2L1 ALDOA MCTP2 GMNN POLR3K DNA2 FEN1 SNRPE RTCB FOCAD RANGAP1 CCNE1 FAH DVL3 CCDC51 CCT7 CDC7 RAD50 SUPT16H LIMA1 CDC20 STOML2 PPP1R8 TMEM147 GNG4 CLUH ESRRA NT5DC2 MED27 ATOX1 BMS1 RAD51 MTHFD1 SEPHS1 CISH COX17 SART3 C12orf10 ERLIN1 CSTF1 DHDDS CXorf40A BAG2	up	*
GO_POSITIVE_REGULATION_OF_SMOOTH_MUSCLE_CELL_PROLIFERATION	0.0058281	0.0478480	0.4070179	-0.3502782	-1.611015	73	EREG HMOX1 CALCRL CDH13 S1PR1 HMGCR MIR27B TGFBR2 HBEGF FOXP1 TRAF6 IL10 PTAFR THBS1 ABCC4 ID2 GNAI2 IL6 JUN	down	*
REACTOME_GLUCOSE_METABOLISM	0.0051283	0.0436709	0.4070179	0.3960637	1.611011	74	NUP107 PGM2L1 GPI GAPDH ALDOC NUP155 TPR PKM PFKP GNPDA1 ALDOA SLC25A10 GCKR GOT2 ALDOB SLC25A13 BPGM NUP205 G6PC3 SLC37A4 NUP85 AAAS PFKFB4 NUP62 HK2 SEC13 PFKM PGAM1 ENO1 PPP2R5D NUP210 NUP93	up	*
MIR144_3P	0.0000002	0.0000093	0.6901325	-0.2753383	-1.610955	432	WEE1 SEMA6A TEK SGK3 HVCN1 ZC3H12C CPEB2 CDH5 KL ZBTB34 CCDC88A MED4 ST3GAL6 CALCRL ZCCHC2 MEF2A NCF2 TET2 OTUD4 TRIB1 ACER3 SEMA6D UBR3 ATP2B1 SH2B3 LIFR MAP3K8 PBX3 NLK FZD4 SPIRE1 ZBTB21 HIPK3 CAV2 SLC7A11 PPP2R2A SLAIN2 GATA3 NFE2L2 ZEB1 HNRNPU PDE4D EPB41L2 PRDM16 TSPAN12 PRKD3 ROCK1 TJP1 MED6 FBXL3 PDE8A MGAT4A PDE3B NR1D2 PNRC1 PAFAH1B1 TP53BP2 FAM76B CDKN2AIP SACM1L MOB4 CREBRF SLC25A3 PRKRA FLT1 NEK7 PIKFYVE CNTN3 ETS1 ADRA1A MTMR9 MORC3 REL ZNF597 PREX2 CGGBP1 FOS CTTNBP2 CCDC85A PPTC7 TSHZ3 XYLT1 RIN2 NIPA2 AP1G1 PDS5B BAZ2B KCTD10 MAP3K2 ATXN1 PPP3R1 APLP2 EXOC1 MYOCD GNA13 ACYP2 MBNL1 ATAD2B INO80D LDLRAD4 CEP170 SPARCL1 EPN2 IQSEC1 LRP12 TRAPPC8 ARHGAP18 DIXDC1 UBE2D1 PTCH1 MEGF9 ZDHHC21 MAP3K4 STAM2 LIMCH1 RASSF8 MAFK PTEN FAM126B RORA NRP2 NAA15 SPATA5L1 SHISA6 SPOPL PURB SLC44A5 EIF4G2 HAT1 ABI1 UBE2V1 RBMXL1 EXPH5 KCNJ6 ZNF800 CRBN ANKS1A KIAA2026 ATP1B1 CCNT2 ADAMTSL3 EBF1	down	***
GO_CELL_CYCLE_PHASE_TRANSITION	0.0000018	0.0000624	0.6435518	0.3240005	1.610687	530	HMGA2 CCNO TRIP13 FOXM1 CEP72 CDC45 TICRR MCM10 CHEK2 BUB1B NEK2 CCNB1 CENPF TIMELESS PAGR1 STOX1 NDC80 PRIM2 BRCA1 TTK CDK4 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 ANLN POLE CNTD2 CEP70 PLK1 AURKB ESPL1 CDC6 TPX2 TFDP2 CCNB2 RBBP8 MCM4 MCM2 TYMS CDC25A ORC1 CCNF DTL MCM8 ZFYVE19 CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 CEP250 CASP2 MELK HMMR BTRC SMARCD3 KNTC1 BUB1 AURKA ODF2 POLA2 SFI1 TPR MCM7 MAD1L1 CLSPN RRM2 CDCA5 PRKDC MCM3 CDC25C SOX4 EGFR TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 MDM2 PKMYT1 FBXL8 BLM PML CNOT3 ERCC2 MNAT1 STXBP4 SKP2 CKS1B CDKN2C ANAPC5 CTDSP2 CDK1 POLE2 CENPJ RFWD3 GMNN E2F1 PSMB5 CCNJL ANAPC7 EZH2 CNOT11 MTBP PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP CEP63 CCNE1 CEP192 CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 NINL TACC3 PSME2 MTA3 AKAP8L FZR1 ANAPC1 PSMD2 ATAD5 PPME1 CDC7 CKAP5 PSMB3 CDC20 RPA1 CHMP4C WNT10B CDK5RAP2 MCM6 PRMT1 MCM5 UIMC1 HAUS6 TFAP4 RCC1 CCNG1 HAUS4 PSMB4	up	***
MIR4667_5P	0.0009576	0.0122990	0.4772708	0.3645730	1.610424	136	EGLN3 PCDHGA10 PPP1R1B CPLX2 GPAT2 PCDHGA9 PCDHGA5 TTF2 TOX3 PCDHGA7 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 PCDHGB4 PCDHGA11 PCDHGA8 RANBP1 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 WDR72 CAPN12 ABCB9 CNGB1 NAA40 OSBPL7 FBXO41 KSR2 PCDHGA2 ZNF687 NRIP2 MAT1A NR6A1 PCDHGB1 ABCC10 BCL2L1 ENTPD3 ANKIB1 SLC38A7	up	*
GO_CELLULAR_AMINO_ACID_METABOLIC_PROCESS	0.0001385	0.0025267	0.5188481	0.3409866	1.610316	264	CPS1 GPT GPT2 BHMT ACMSD PSPH NOXRED1 SLC25A21 PHGDH GMPS ALDH18A1 GLDC PAH ACY1 SHMT2 DPYS AARS2 GFPT1 EEF1E1 IDO1 BPHL LARS2 GCAT MCCC2 AIMP2 PYCR2 TARS2 OAZ3 SARS2 ASS1 AHCY PSMD4 CAD TST HARS2 PLOD2 GOT2 OAT PSMB5 PSAT1 PSMC4 HYKK PARS2 SCLY FAH PSMA5 GSS ALDH7A1 AARSD1 PSME2 ENOSF1 ASNS PSMD2 SLC1A3 MAT1A YARS2 NAGS PFAS PSMB3 IARS2 HPD FTCD SIRT4 NAT8L PHYKPL ASRGL1 HIBADH PRODH AMT GGT5 PSMB4 GAD1 FARSA DDAH1 PYCR1 AGMAT FARSB NOS1 EARS2 MTHFD1 SEPHS1 PCBD1 BCAT2 FOLH1 ACAD8 NQO1 SARDH BCKDK NOS3 HGD DPYD PSMB10 PSME1 ASL MPST PLOD1 GCSH MTR SHMT1 MTRR MARS2 NIT2 PPA1 PLOD3 TXN2 AFMID MCCC1 PSMD3 HAL CARNS1 HAAO TPH1	up	**
GTGTTGA_MIR505	0.0030378	0.0293950	0.4317077	-0.3399244	-1.610224	83	CITED2 YPEL5 OTUD4 USP47 UBR3 ATP2B1 RANBP9 SIRPA FAM122A PDE4D UBE2D3 ARNTL GPR85 KIAA0408 GPBP1 SLC25A3 LRCH1 CELF1 DHX15 CREB1 CGGBP1 YTHDF3 TTBK2 KHDRBS1 MBNL1 EPN2	down	*
GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN	0.0005364	0.0077822	0.4772708	-0.3079683	-1.609586	162	GIMAP8 LRRFIP1 SLC6A12 CDH13 MEF2A ALAS1 FRAT1 NFATC3 SCARF1 STARD4 TACC1 ENTPD1 PARVG TCF7L2 EVI2B VAMP5 HLA-DQA1 MAFF ZDHHC20 CLN8 MYO1C DDHD1 OASL UTRN MITF GSTO1 PCGF5 MALT1 DOCK8 BLOC1S6 LMCD1 ICAM2 AKIRIN2 TGFB1I1 ATP6V1A CBFA2T3 ATP6V0C HBP1 DECR1 KAT2B CLEC2B TAGLN MBNL1 CCL20 SELPLG CCDC69 BLOC1S2 SCPEP1 RAD9B CTSC EDN1 LPAR6 ATP6V0A1 CSF2RB SPPL2A CLEC4E ITGAL SLC38A2 FAR1 DNAJB4 ANKHD1 NMI ZBTB46	down	**
GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP	0.0005364	0.0077822	0.4772708	-0.3079614	-1.609549	162	PRMT8 TMEM100 ABHD5 P2RY1 BACH1 SPATA1 HPS5 RCHY1 PDE2A APOD RRAGC HBEGF ABCG2 LAMTOR3 TIPARP ZMIZ1 IL10 CSRNP1 TLE4 KLF9 ZFAND5 SCAF4 TANC1 CLN8 PRCP GZF1 BCAR3 CABLES1 SH3BP5 CPEB4 ST6GALNAC4 RABGAP1 VPS26A OSM ATP13A3 GPRC5A GAS2L3 SMCR8 ZFYVE9 FEM1B ANKRD12 N4BP2L2 ABL2 CEP170 THAP6 SLC2A9 BCAM OSER1 STAM2 RAD9B JMJD1C MAFK FNIP2 SNX15 ZFAND2A SPHK1 RABGEF1 NAF1 ACVR1C	down	**
GO_TELOMERE_ORGANIZATION	0.0024767	0.0252333	0.4317077	0.3660830	1.609391	131	NEK2 PRIM2 PIF1 POLE NABP2 AURKB CCT6A CCT2 EXO1 CCT5 POLA2 ATR POLD2 SMARCAL1 PRKDC XRCC1 BLM PML PARP1 TERC POLE2 CCT3 DNA2 FEN1 RECQL4 TEP1 TELO2 CCNE1 DCLRE1C SMG5 RAD51D FBXO4 POLD1 SLX4 CCT7 RAD50 YLPM1 RPA1 PRIM1 RTEL1 RFC5 RAD51 TNKS1BP1 SIRT6 PNKP APEX1 NAT10 EXOSC10 NHP2 DCLRE1B DCLRE1A POT1 XRCC5 CTC1 POLD3 XRCC6 ZBTB48 HNRNPA1 RFC3 POLE4 RFC4 HUS1B SRC MAPKAPK5 PCNA	up	*
BURTON_ADIPOGENESIS_2	0.0039869	0.0361740	0.4070179	-0.3552357	-1.608851	67	RAMP3 SIDT2 SASH1 SAMHD1 FOSL1 TGFBR3 IL1RL1 GNPTAB AVPI1 ITGA5 MCL1 SNAI1 CLIC4 PER2 SLC6A6 TLL1 PGD RHOJ GSTO1 PRKCE	down	*
MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP	0.0000752	0.0015238	0.5384341	-0.2944659	-1.608699	216	RAB11FIP1 KMO SLC12A6 GATA2 ZC3H12C ADCY9 EMP2 DPYSL2 ADCY4 RAMP2 RCOR1 FYN ECSCR AKAP7 ADRA1D YPEL5 FUCA1 TRIB1 ZEB2 SH2B3 ASAP1 CHMP1B FZD4 MALL SLC7A11 ABHD6 SIRPA SPTBN1 CES1 CD58 FLI1 KDSR ADARB1 ROCK2 TBC1D9 EPOR ZSWIM6 PAQR5 GRK5 NPR3 ID2 IGFBP2 LBH MEDAG ARHGDIB IL17D CABLES1 LRCH1 KCTD12 JAK1 PODXL FAM43A SIGLEC15	down	**
GO_NEUTROPHIL_MIGRATION	0.0025052	0.0254525	0.4317077	-0.3446419	-1.607813	79	CXCL3 IL1A PECAM1 IL1B CCL3L1 C5AR1 IL1RN IL23A JAM3 PDE4D CCL22 BST1 CCL3 CXCL2 CCL4 XCL2 FCER1G TGFB2 NCKAP1L RAC2 RHOG CCR7 DAPK2 CXCL5 CD74 VAV3 ITGA9 LGALS3 PDE4B CCL20 WDR1	down	*
GO_REGULATION_OF_CELL_CYCLE_PROCESS	0.0000001	0.0000037	0.7049757	0.3198433	1.606815	633	HMGA2 PKHD1 TRIP13 DDX11 FOXM1 CEP72 SPICE1 KIF20A MDM1 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF PAGR1 STOX1 NDC80 BRCA1 TTK CDK4 SMPD3 RACGAP1 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN STIL CEP70 PLK1 AURKB PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 TFDP2 RBBP8 CDC25A PRC1 ORC1 CCNF DTL ZFYVE19 CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 CASP2 HMMR BTRC SMARCD3 KIF23 MKI67 CUL9 CUL7 FBXO43 KNTC1 RHNO1 KIF3B BUB1 MSX2 MAP10 GPER1 AURKA CBX3 ODF2 SFI1 TPR MAD1L1 MSX1 POC1A CLSPN CXCR5 RRM2 CDCA5 PRKDC FSD1 TOM1L1 KIF11 GPSM2 HORMAD1 CDC25C SOX4 EGFR TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 AKT2 MGA PKMYT1 BLM PML CNOT3 ERCC2 STXBP4 PSRC1 INCENP KNSTRN CDKN2C NUSAP1 CBX5 ANAPC5 CTDSP2 CDK1 CEP97 CENPJ RFWD3 E2F1 PSMB5 ANAPC7 FEN1 EZH2 CNOT11 SPAG5 EGF RAB11FIP4 MTBP PSMC4 MAD2L2 KLHL22 FGFR1OP GIPC1 MYO19 ANKK1 CEP63 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 NINL TACC3 PSME2 MTA3 TRIM37 MYBBP1A FZR1 PKP4 NUDT16 KIF20B ANAPC1 SND1 CDK13 PSMD2 ATAD5 CDC7 ANKRD31 SH2B1 CENPV CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B BCL2L1 CHMP4C WNT10B CDK5RAP2	up	***
GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN	0.0002531	0.0042074	0.4984931	-0.3018943	-1.606726	177	ACP5 SIDT2 USP12 TMEM126A C18orf32 SNX10 GIMAP8 PTPRE LIPA TMOD3 SAMHD1 BACH1 CALCRL SYS1 CYB5A LAMTOR3 ZYG11B ATP10A EVI2B PRKD3 SELL DUSP11 LBH CLK4 SMAD7 UNC5A AKIRIN1 LMBRD1 RSRC2 SLC25A33 S1PR4 SNAP23 RHOBTB2 KCTD12 TYROBP OSTM1 UBAC2 GMFG GRB2 RC3H1 RPS6KA1 YWHAZ SNRK PLCG2 CD164 SRSF6 HBP1 ACADL MFNG IL18RAP SEC63 TRAPPC8 ESYT1 TAB2 GIMAP4 EHD3 FEZ2 IRF2 YTHDC1 EGR1	down	**
GSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN	0.0044245	0.0390932	0.4070179	0.3664173	1.606140	130	LEMD1 HABP2 ADH1C HJURP AP3B2 PROM1 NRG2 CDCA2 AURKB MST1L ESPL1 THTPA ZNF862 GTPBP3 RRM2 PASK PYCR2 CLDN9 ACVR2B-AS1 AFAP1L2 EPHA1 NPM3 LRRC4 PEG10 ANAPC7 C22orf15 MTA3 DPH2 PINLYP JTB KIAA1549 CENPV DGKA HMGB3P22 WNT10B IGFL2 CHTF8 COL5A3 USP21 HHLA3 AGMAT ZNF93 TYSND1 LINC00240 RELL2 TCF3 FGFBP1 SLC35G1 TMEM201 APOBEC4 PDK2 MST1 HUWE1 AP2B1 LTK	up	*
GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_DN	0.0002745	0.0045288	0.4984931	-0.3059702	-1.605820	167	HMOX1 CLDND1 BACH1 ST3GAL6 NEDD4L CITED2 CYB5R3 NR3C1 ZBTB2 ITGA5 MAP3K8 IFI30 ANPEP RNASE1 STOM SRGN TCAP TIPARP ZFAND5 UBQLN1 RBMS1 P2RY2 CCL4 SFTPD PIK3C2A MATN2 GNAQ AFF1 RSRC2 IL17D JUN ST6GALNAC4 JUNB PTGER4 PCGF5 UNC13B SNRK AGFG1 CD164 TGFB1 EHD1 TEC NAB1 CD86 PIM1 BAG6 CCR1 ETS2 CEBPD SOAT1 HNRNPC LYST MCOLN2 TNFSF9 RHOT1 RNH1	down	**
GO_POSITIVE_REGULATION_OF_CYTOKINE_PRODUCTION	0.0000044	0.0001382	0.6105269	-0.2788561	-1.605809	358	POLR3H EREG IL17RB IL1A HMOX1 FCN1 SCIMP SIGLEC16 CCM2L SPN IL1B MNDA LRRFIP1 LPL MYD88 C5AR1 IL1RL1 IL1RN SLC11A1 IL23A FGR HEG1 CD36 ANXA1 TNFRSF8 ADAM17 CLEC7A HSPB1 RNF125 GATA3 RGCC IL18R1 TRAF6 SPTBN1 CRTAM WNT3A ARHGEF2 PDE4D CD58 NODAL IL10 ROCK2 BIRC2 CASP1 PTAFR THBS1 LY96 FAM49B CCL3 NFKB1 CADM1 PTPRC HPSE TLR4 FCER1G CLEC9A IL17D CD80 IL6 CD160 PSEN1 APPL1 SEC14L1 CARD8 TYROBP HSPA1B IFNGR1 PTGER4 CCR7 PIK3R1 CD83 IRF8 CREB1 OSM MALT1 TIGIT CD34 PLCG2 PELI1 MBP CD74 WNT11 IRF5 CHIA TGFB1 AKIRIN2 CD6 CD86 CD81 KLRC4-KLRK1 ORM2 PDE4B IL18 RIPK2 NLRP3 HAVCR2 CREBBP KLRK1 MCOLN2 AIM2 RORA PUM1 ATF4 FLT4 SPHK1 CSF2 CYBA EGR1 SERPINE1 ATF2 CLEC4E C5 TREM2 TBC1D23 NFAM1 POLR2L WNT5A BCL10 AKAP12 HMGB1 DDX21 EP300 CD3E IRF1	down	***
MIR22_3P	0.0008748	0.0114657	0.4772708	-0.3210652	-1.605799	115	RCOR1 PRPF38A TET2 KCNAB1 WWC2 PPP1R15B MTF1 KLF6 AKT3 MTHFR EPB41L2 ARRB1 PPM1K LIN7C CLIC4 FAM49B NPAS3 KIRREL3 NUS1 BTG1 PRCP CD80 PDIK1L MED28 INPP5B RASSF10 EPC1 CREB1 HOMER1 SNRK DAGLA ZFYVE9 MTMR2 ANKRD13A RGS2 SESN1 LRP12 NLRP3	down	*
E2F_Q6_01	0.0008032	0.0107296	0.4772708	0.3484650	1.605196	195	GRIA4 CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A ORC1 XPO5 EPHB1 RANBP1 CASP2 MELK PAQR4 RND2 AP4M1 MAP3K13 CACNA1G MCM7 RRM2 PRKDC MCM3 LIG1 TOPBP1 KLHL35 MSI1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CNPY2 MEA1 CBX5 POLE2 GMNN E2F1 UNG EZH2 TNPO2 LRRC56 KPNB1 DNMT1 ZNF687 ACBD6 FANCG INTS7 NDUFA11 CCDC151 PCSK4 ANP32E DNAJC11 POLD1 MARCKSL1 ETV4 SASS6 KLHDC3	up	*
MODULE_52	0.0000102	0.0002826	0.5933255	0.3305592	1.605032	368	RIBC2 TRIP13 PLAT FOXM1 SPOCK1 CDC45 PAX9 BUB1B PROM1 PRSS2 CCNB1 CENPF IGF2BP3 NRG2 NPAS1 SLC2A1 DDIT4 SORD TTK GTSE1 GMPS SPP1 MMP1 PLK1 CENPA PTTG1 ESPL1 TPX2 E2F3 CCNB2 MCM2 UMPS MYBL2 CCNF CCT6A SRPK1 ZWINT TNC CASP2 HMMR NUDT1 CHAF1A PRB4 EEF1E1 TOP2A SEMA6C AGT MYO10 CARD10 POLD2 MSX1 RRM2 SLC22A18AS KIF11 MCM3 LMNB1 SOX4 MDK RBP1 CD24 SLC9A3R1 MAD2L1 SCAMP5 PKMYT1 FDXR FADS2 CLDN9 MGLL PON2 TMED3 CDKN2C TMEM106C PLOD2 KRT18 CDK1 FAT1 UCK2 E2F1 UNG STEAP1 PEG10 FEN1 EZH2 NUP205 ETFB IGSF3 CBX1 DDT ITPR3 RNASEH2A TBX1 LGR5 DLGAP5 CHST3 ALDH7A1 LMNB2 COL5A2 DTYMK DBN1 ASNS KRT19 FHL2 LTBR TYRO3 MAT1A CHPF KLHDC3 CKAP5 CDC20 RRP9 CXCL1 MCM6	up	***
ACTGAAA_MIR30A3P_MIR30E3P	0.0003304	0.0052783	0.4984931	-0.3049749	-1.604713	168	EPAS1 OSBPL11 CAV1 QKI VAMP2 YPEL5 NR3C1 CBL FRAT1 FAM49A ZEB2 DNAJB14 EIF1 ZBTB21 FOXP1 FOXJ3 SFRP1 NRARP RUNX1T1 ZFAND5 STX3 ELK3 LIN7A SIAH1 SLC25A33 CDC40 DNAJC27 LRRTM2 RNF141 DUSP8 SP3 CELF2 PBRM1 AP1G1 KIAA0232 SRSF4 ZFYVE9 CDC37L1 TSPAN14 ATXN1 KCNA3 TOB1 ACYP2 TCF7L1 ARPP19 POLR2M CREBBP SRSF10 ISCU PTEN CYTH1 DLST PAIP2 FAM13B MACROD2 PSIP1 EGR1 RBMXL1 SH3GLB1 EYA3 CSNK1G3 DNAJB4 TSC22D2 ZNF22 EP300 MEF2D	down	**
GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS	0.0000000	0.0000000	0.8140358	-0.2534657	-1.604348	882	TRIM71 ANGPT4 SLC24A4 RBP4 EPAS1 CLEC1B SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK DLC1 TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 DCSTAMP WNT4 EMP2 BMPER RAMP2 PTPRB BMP2 CDH5 ENG FIG4 FOLR1 EGR2 TMOD3 ECSCR SOX17 WDR74 CAV1 CITED2 CALCRL CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 PRKAR1A MEF2A CDC42 MIR27B TGFBR3 CD9 AGTPBP1 EPB41L3 TGFBR2 HSPG2 CASP9 RHOA ZEB2 APOD CD36 ANXA1 TBX2 MIR146A MYOZ1 MMRN2 PTPRM ADA FOXA2 ADAM17 WNT2B PLXNA2 CSRP1 ITGA5 CLEC14A HSPB1 LUZP1 ANPEP GATA3 NR4A1 JAM3 RGCC TRAF6 NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A SOX7 TCAP MTHFR PDGFA FOXC2 NODAL RHOB HIF3A GPR4 IL10 ROCK2 AMOTL1 SNAI1 NRARP FOXO1 TBX4 TNFSF12 TSPAN12 KLF4 ROCK1 VASP THBS1 ADAMTS9 CLDN5 MPL CLIC4 SEC24B FMNL3 PDE3B ITGAX EPGN HOPX HPSE MIR24-2 RECK CD53 PIK3C2A ELK3 INHBA ADIPOR2 TBX5 SH2D2A PEF1 MYH11 PAFAH1B1 NUS1 PTGIS DCHS1 HES1 PLCD1 ANXA3 TANC1 TGFB2 MMP19 LMOD3 TOPORS MTPN SRF BTG1 PRCP RBPJ HESX1 FLT1 TMOD1 IL6 WASF2 PKNOX1 CD160 PSEN1 PIKFYVE NDNF JUN NOTCH1 GABPA ETS1 TYROBP JUNB JAK1 RHOJ PODXL SKIL SP3 ACKR3 HERC1 GRB2 KBTBD8 NPR1 RC3H1 PRKACA MCAM CD34 AGFG1 POGLUT1 RRAS KLF2 EHD2 WNT11 TGFB1 EHD1 VAV3 ISM1 JMJD6 MTMR2 MIR23A MMP15 MIA3 PIM1 CNTNAP1 COL15A1 CD81 MEIS1 CLASP2 GATA6 MFNG GNA13 ACTN2 CALB1 ETS2 SMAD2 ELF5 UNC13D FGF2 IL18 FKBP1A VASH1 WDR1 EGFL7 EPB41L5 LMOD1 EPN2 OSR1 SEMA4A RTN4 CXCR4 TMOD2 PTCH1 SP100 EPHA2 PARVA GLUL STK4 CUL3 RET RAPGEF3 EDN1 ETV2 FOXJ2 PTEN SKI SYNPO2L FGFR1 RORA NRP2	down	***
GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS	0.0032449	0.0310004	0.4317077	0.3793643	1.604106	103	AK4 PRTFDC1 GMPS AKR1C1 UMPS DPYS NME1 DNPH1 DLG1 CARD11 NT5C1B NME9 NME5 AHCY CAD LRGUK UCK2 ATIC OARD1 UCKL1 UPP2 DHODH TK1 DTYMK FUCA2 NT5M APOBEC2 NME4 ABHD10 NME7 GMPR2 TK2 AKR7A2 APOBEC3B DGUOK DPYD APRT OPA1 PRPSAP2 TYMP AKR1A1	up	*
BENPORATH_ES_CORE_NINE_CORRELATED	0.0044101	0.0390059	0.4070179	0.3851742	1.603860	88	TRIP13 FOXM1 E2F8 TBX19 SOX9 E2F3 TFDP2 MYBL2 MDFI WDHD1 SOX4 YEATS2 SOX11 ETV7 SUPT5H E2F1 TCF20 EZH2 ILF2 SSRP1 MYBBP1A SAP30 HMGA1 TFCP2L1 CREB3L2 ETV6 SMARCA4 MLXIP GTF3C2	up	*
KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP	0.0007816	0.0104957	0.4772708	0.3544316	1.603519	173	CDC45 COIL PRIM2 RACGAP1 IQGAP3 E2F8 CCNB2 TYMS PRC1 XDH CIB1 SPDL1 NUDT1 MKI67 TOP2A RRM2 CDCA5 MRPL27 KIF11 LMNB1 CDC25C LIG1 PERP GNPDA1 ALDOA CKS1B CDKN2C CMAS NUSAP1 ASF1B CDK1 BIRC5 ETFB DDT DAP DLGAP5 PSMA5 TACC3 MNS1 KIF22 CASP7 CNDP2 DHRS1 TIMM13 USP18 CDC20 MRPL41 MCM5 EIF3D NFE2 ERGIC3 EIF3K DCPS BANF1 HK2 NDUFA8 RPN1 ADAM8 LXN COX17 ACSL5 NCAPH PLAC8 PRRC1 ISYNA1 NAT1 GSTT2 MRPL43 CDC34 BATF PTGR1	up	*
GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME	0.0035076	0.0329938	0.4317077	-0.3441662	-1.603430	81	SRSF7 DYRK1A RBM7 TRA2B RBM4 SRSF2 HNRNPU CWC22 SRSF5 REST SRSF3 CELF1 DDX17 WTAP SMU1 DDX5 MBNL2 CELF2 SRSF6 HNRNPA2B1 JMJD6 SRSF4 KHDRBS1 MAGOH MBNL1 HNRNPK NUP98 SRSF10 THRAP3 YTHDC1 RBMXL1 SAP18	down	*
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP	0.0000640	0.0013278	0.5384341	0.3372651	1.603405	281	DKK1 TRIP13 TP63 HKDC1 DDX11 SLC5A5 GALNT6 CCNB1 PSPH CHST4 PRIM2 SORD PPP1R14D IRS1 METTL1 ECT2 CCNB2 STC2 RBBP8 MCM4 MCM2 RAD54B XDH TRIM45 LSM5 WDR62 BZW2 KCNN4 MKI67 MRPL15 PCCB CYP24A1 HOMER3 PUS7 BPHL POLD2 MCM7 MAD1L1 PRKDC GCAT AMACR PEX6 DDR1 CAD ZNF507 PML PLA2R1 NCAPG2 IGFBP5 KRT18 MERTK ESRP1 LARP1 SSX2IP ARHGAP32 ROGDI RHBDD3 SLC22A5 SAP30 FXYD3 ENPP2 MARCKSL1 PFAS TSTA3 ERBB3 NPRL3 CXCL1 CKMT2 PRMT1 CLUH LRCH4 ZDHHC11 SF3A2 WDYHV1 PRMT5 AKAP6 LRRC14 FARSA NCDN SCRG1 FBN2 GRM6 SOX12 CELSR2 UBAP2L RAB25 PAICS EPHB4 ENO1 PPP2R5D HGF CORO1B LYPLA1 PCGF2 PDK2 BCL7A TBC1D10B ABHD2 TLE2 TCFL5 MPZL1 NCKIPSD SNTA1 FCGBP CEP112 ELL3 INHA ANK1 NUP214 EPS15L1 SLC12A9 GRHPR IPO4 RNF170 GPR27 HMBS GPR137 PTP4A3 CIC TSPAN15 NDUFA10 EIF4EBP1 ZC3H3	up	**
HALLMARK_KRAS_SIGNALING_DN	0.0015098	0.0173371	0.4550599	0.3726760	1.603186	114	RIBC2 HNF1A SLC5A5 KRT5 TG PKP1 CHRNG TENM2 SLC6A3 KLHDC8A KRT15 CLSTN3 STAG3 ZNF112 IFI44L IL12B TGM1 SIDT1 EDN2 FGGY MYOT EGF NRIP2 GPRC5C SPTBN2 DLK2 THRB NR6A1 TFCP2L1 PRODH EDAR CLDN16 YBX2 DTNB NOS1 GTF3C5 CELSR2 ENTPD7 MYO15A IDUA COPZ2 CAPN9 CDKAL1 GP1BA HSD11B2	up	*
GSE21360_PRIMARY_VS_SECONDARY_MEMORY_CD8_TCELL_DN	0.0012369	0.0149806	0.4550599	0.3619686	1.602877	144	TFPI2 GABRP FAM153A PTPRR PTPRH MST1L SLC7A9 DYNC1I1 GON4L INSRR CEL AGT MPO SETDB1 FHOD3 BRD9 GPR135 FUT2 ZNF512B DCLK1 FASTK HARS2 PABPN1 ITGB8 NOP2 ULK1 POLR2H ATP7B DNAJA3 MNS1 ZNF239 PRRG2 NAT9 RDH16 DUS1L WNT10B BSN MVP SPSB3 ARFGAP1 KRTAP5-9 GTF3C2 ATOX1 R3HDM4 FMOD MAU2 TIMM44 BCAT2 ARHGEF10L ZBP1 TMEM161A RANGRF KLK10 SNTA1 BRD4 BNIP1 MEN1 SAP30L DHPS KLF5 PDE1A TCHH	up	*
REACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS	0.0002975	0.0048528	0.4984931	-0.3004747	-1.602608	183	FFAR4 CXCL3 HCRTR1 GPR17 CXCL16 EDNRB F2RL3 LHCGR P2RY1 GPR65 HCAR2 CCL3L1 CCRL2 ADRA1D TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 ANXA1 SSTR1 NMUR1 ADRB1 ADRB2 GPBAR1 GPR4 PTGIR CCL22 TACR2 PTAFR CCL3 P2RY2 CXCL2 CCL4 PTGER3 XCL2 GNRH1 S1PR4 HCAR3 HRH1 ADRA1A PTGER4 CCR7 ACKR3 GPR183 PTGER2 SUCNR1 CXCL5 GPR37L1 CCR4 FPR2 CCR1 GPR18 QRFP CCL20 CCR6 OPN3 HTR6 CXCR4 CCR9 ADORA2A EDN1 HEBP1 LPAR6 NPW C5AR2 CNR2 CX3CR1 C5 FPR1 BDKRB2 FPR3 UTS2B S1PR5 GPR55	down	**
GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	0.0011198	0.0138746	0.4550599	0.3525848	1.602519	178	TFPI2 CEACAM1 RUVBL1 SORD C12orf66 CDK4 ALDH18A1 EIF3B CCT2 RANBP1 F2RL1 PUS7 WDR3 POLD2 LMNB1 AHCY DCTPP1 CAD PHB DYRK2 PPIL1 CCT3 ATIC TRAP1 NARF LARP1 PDK1 NUP205 POLR1C NOP2 TSPAN17 SULT1B1 PFAS GPATCH4 CXCL1 NOL6 UTP20 HEATR1 EXOSC5 WDYHV1 PMS1 MRPS25 RNF157 CLUAP1 APBA2 FARSB POLR1B BCL6 POLR1A DTNBP1 EIF4G1 CMTM8 TP53 SRPRB PAICS SBNO2 EPHB4 CISH SFXN4 ENO1 RRS1 MRTO4 SFXN2 SRM URB2 C3 LRP8 TSPAN3 CEP112 HNRNPAB UBE3C NUDCD1 DHPS CTPS1 GTPBP4 WDR12 GTF3A HIF1A	up	*
GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP	0.0007566	0.0102200	0.4772708	0.3542846	1.602419	171	CEP72 SPATA24 HJURP CDC45 FANCI NEK2 SRGAP3 GTSE1 CENPA SRPK1 NCAPD2 MRPS35 SPDL1 WDR90 CASP2 DNPH1 NUDT1 KIF23 CUL7 CCDC77 SAE1 MAD1L1 MPHOSPH9 CPD WDHD1 BRD9 AHCY DCTPP1 XRCC1 BRIP1 ALDOA EFCAB11 NEIL3 ANAPC7 FEN1 DYNLL2 MTBP DAP RNASEH2A CCNE1 TRIM24 PSMA5 NMRAL1 MBD4 IQCG ANP32E CLTA RAD50 GEMIN6 PTER MAN2A1 RPUSD1 PIGU SNRPD1	up	*
PR_01	0.0021445	0.0226533	0.4317077	-0.3202990	-1.601800	109	CD52 GREB1 TIE1 WNT4 BDNF VAMP2 MTMR10 ELMO1 BRINP3 CD36 TNIP3 RANBP9 SRGN SLC7A8 GSDMA CEP57 DSTN FAM76B NCKAP5 TECTA SENP3 RWDD1 FAM189A2 ETS1 JPH1 SKIL GRB2 CASZ1 MBP KHDRBS1 JMJD1C RNF38 CHCHD7 DNAJA2 EPG5 PLAG1 ADAMTSL1 RAB37 CD109 KCNJ1 ZNF654	down	*
GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN	0.0004122	0.0063017	0.4984931	-0.3021439	-1.601526	181	DNAH17 SIDT2 LPIN2 SGK3 PECAM1 INPP5K DDX6 MKNK1 NR3C1 CBL PDE2A UBL3 EIF1 CSGALNACT2 NFE2L2 SPTBN1 MCL1 CD37 CCNI SRSF5 RNFT1 MAFG KLF7 HPSE PLEKHB2 GNAQ RPL17 RYBP NEK7 NXF1 VAT1 KCTD12 RAPGEF1 CCR7 IRF8 COBLL1 STX5 SRSF6 ING3 ZFAND6 GSAP DUSP5 FCGRT TOB1 JUND LAT TRAPPC8 FBXO30 ING2 CEPT1 ABI3 CYTH1 IQGAP1	down	**
GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP	0.0012070	0.0147136	0.4550599	0.3529436	1.601509	176	ZG16B AK4 KIF18B IFI27L1 PHGDH E2F8 TRAIP NABP2 NUF2 TRIB3 RAD54B TDRKH XPO5 ZFP64 DCTN2 TNFRSF11A EMC9 COPG1 EME1 ODF2 RRM2 ERAL1 MRPL27 TOPBP1 DCTPP1 PIH1D1 PKMYT1 MRPL37 UNG RNF181 NARF NUP205 LRRC42 RECQL4 IFI27L2 RHOC DPP3 FAH CLTA GALNT3 POLD1 CENPM BCL2L1 CDK5RAP2 SNRPD1 PFKFB4 RTKN HAUS4 STK39 FARSA TM7SF3 RFC5 TPGS2 NME7 WDR76 CPOX SMC2 RPN1 ADRM1 ZBTB32 PCBD1 TUBA1C E2F7 KIF24 PRKAG1 NQO1	up	*
GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN	0.0003259	0.0052119	0.4984931	-0.3013792	-1.600899	179	LIPA LRRFIP1 THBD SIK1 KIAA1109 MEF2A IL1RN OTUD4 PFDN1 ANXA1 COQ7 MAP3K8 HSPB1 KLF10 PPP2R2A RB1 NDEL1 CD58 CASP5 TMED5 STX3 VRK2 VIM ZBTB43 DUSP1 N4BP1 FKBP15 TDRD7 PROCR PDHX ELF1 NSMAF DCTN6 OASL TMEM251 PPP1R15A CGGBP1 GRSF1 AGPS CD164 PTP4A1 NUP153 BCAS2 GSAP TGIF1 TOB1 DECR1 GPR18 PGGT1B CGRRF1 NT5C2 SP100 ISCU MAP3K4 CTSC DOCK10 CREG1 IRF2 SETX PHYH	down	**
REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	0.0051301	0.0436709	0.4070179	-0.3459640	-1.600840	76	PPARG FABP4 LPL EGR2 MED4 CD36 MED19 MED26 MED11 KLF4 CEBPA MED6 NFKB1 NCOA1 MED28 MED30 TGFB1 RXRA CEBPD CREBBP SREBF2 THRAP3 CCND3 MED17 MED31	down	*
MODULE_27	0.0000107	0.0002946	0.5933255	-0.2896894	-1.600307	281	RAMP3 TEK OLR1 ASGR1 EDNRB PPARG SFRP4 TIE1 GPR65 PTPRE THBD FOLR1 FCER1A CALCRL ADCYAP1R1 C5AR1 TGFBR3 IGSF6 LILRB3 CD8A TNFRSF8 PTPRM CD5 HBEGF LIFR CHRNE ITGA5 ANPEP PRSS12 ADRB1 ADRB2 IL18R1 EPOR PTPRO GPA33 PTAFR PLAUR MPL NPR3 CDKN1A ITGAX PTPRC SELP AXL FCER1G CD300C EVI2A IL7R PTH1R PDK4 CD8B HCAR3 CD80 IL2RB PRPH2 HRH1 IFNGR1 GPR183 PTGER2 UNC13B GPRC5A GRIK1 GPR37L1 KLRC2 CR1 ITGA9 GLRA3 CD6 FPR2 CD86 CNTNAP1 GLRA1 LGALS3 CCR1 FCGRT RXRA ICAM1 CXCR4 EPHA4 CCR9 EPHA2 ADORA2A KIT CD3G KLRK1 GPR171 P2RX1 FGFR1 RORA LDLR LPAR6 MS4A2 CSF2RB GHR CNR2 NR4A2 CX3CR1 PRKCH ITGAL	down	***
GO_NEGATIVE_REGULATION_OF_CELL_ACTIVATION	0.0002670	0.0044169	0.4984931	-0.3054050	-1.599943	163	CD300LF FOXF1 HMOX1 SPN MNDA THBD PRKAR1A CD9 FGR ANXA1 SH2B3 FBXO7 HLX PAG1 GRN SFRP1 PDGFA IL10 NRARP DUSP3 SOCS5 PTPRC AXL ID2 SFTPD SMAD7 INHBA UBASH3B GNRH1 CD80 PDE5A TYROBP RC3H1 TBX21 CST7 TIGIT PELI1 RUNX3 CD74 MILR1 CYGB LRRC32 CD86 LGALS3	down	**
GO_SYNAPSE_ASSEMBLY	0.0015573	0.0177351	0.4550599	0.3718860	1.599788	114	DKK1 EPHB3 GABRB3 SIX4 SDK2 COLQ PCLO SIX1 SLITRK5 EFNA5 EPHB1 PPP1R9A CLSTN3 TPBG CEL SDK1 OXTR SLITRK6 DLG5 DNER GABRB2 LRRC4 GNPAT ADNP LRFN3 EPHB2 SPTBN2 MDGA1 NRXN2 UBE2V2 BSN MUSK CDH1 DBNL NLGN2 CDK5 NTN1 EIF4G1 FBXO45 NLGN1 PLXNB1 GRIN1	up	*
LINDGREN_BLADDER_CANCER_CLUSTER_1_DN	0.0000274	0.0006492	0.5756103	0.3324463	1.599710	332	MNX1 PCSK6 TRIP13 CDC45 NEK2 CCNB1 CENPF DEPDC1 TTC39A BRCA1 CDCA7 CDCA2 RACGAP1 GTSE1 HILPDA KIF14 TRAIP POLE TOMM34 PLK1 CDCA8 CENPA PTTG1 CDC6 CCNB2 CDC25A MYBL2 PRC1 ORC1 MCM8 ZWINT CDT1 TNC TJP3 MELK EXO1 NUDT1 TNFRSF11A KIF23 PAFAH1B3 BUB1 TOP2A IDO1 AURKA PMS2P4 SAE1 KIF2C POC1A MPHOSPH9 RRM2 RGL1 RBM28 WDHD1 RAD54L KIF11 CHAF1B TRIM11 SLC9A3R1 KDELR2 ACSF2 IDH2 DYRK2 PSRC1 CASP6 CKS1B NCAPG2 CDKN2C CDK1 HDGF UCK2 BIRC5 TNK2 NAV2 E2F1 BPGM EZH2 RNASEH2A CCNE1 DLGAP5 TACC3 MNS1 COL5A2 DNM1 TK1 ENAH ATG9B GINS2 SLC1A3 CDC7 ERBB3 POP7 CXCL1 MCM6 KIF21B RAI14 MCM5 NFE2 CREB3L2 PSMB4 ATAD2 HTRA3 NUP62 ZNF286A PRSS8 PYCR1 MAP3K14 SMARCA4 VDAC1 BLVRB ABCF2 RAD51 SEC13 TCF25 ERBB2 SLC12A2 B4GALNT3 CENPE ADAM15 CGN CELSR3 SBNO2 CDC25B UBE2C CISH BCAT2	up	***
BMI1_DN_MEL18_DN.V1_UP	0.0017773	0.0195453	0.4550599	-0.3167017	-1.599499	123	WEE1 IL1A TEK SIK1 FOSL1 CDH13 CDC42EP2 KCNN3 ZEB2 TNFRSF8 HBEGF ITGA5 TNIP3 SLC7A11 LCP1 ADRB2 SLC19A1 TFEC BST1 PLAUR KLF7 ATF3 INHBA ARL4A IL7R ANXA3 TGFB2 FAM189A1 C2CD2 APBB2 PODXL TNFRSF9 OGFRL1 GFPT2 EHD1 PIM1 TAGLN TIMP3 EDN1 TNFSF9 COL13A1 NRP2 PIEZO1 CSF2 GREM1 FJX1 FADS3 LHFPL2 HAS2 PIK3CG	down	*
SMID_BREAST_CANCER_ERBB2_UP	0.0022280	0.0232638	0.4317077	0.3716602	1.598897	117	IGHV4-61 TSPAN8 ALDH3B2 ABCC2 BIK GALNT6 FUT3 PLEKHA6 EFNA3 CATSPERB FA2H ABCA12 IGKV4-1 GRB7 LRRC31 GSDMB SLC2A10 FGG CPD TRPV6 GCAT ASS1 C2orf72 NOL3 TSPAN1 SERHL2 QPRT SLC12A1 S100A9 PRMT7 KIAA0100 ABCC3 MED24 PRODH FFAR2	up	*
GO_PLATELET_DEGRANULATION	0.0035949	0.0335810	0.4317077	-0.3225304	-1.598462	102	PECAM1 CLEC3B MMRN1 CTSW CD9 GAS6 CD36 ANXA5 SRGN PDGFA CFD THBS1 FAM49B ABCC4 SELP FCER1G PLEK VWF TGFB2 PHACTR2 CYB5R1 TAGLN2 CALM1 TGFB1 TMX3 CDC37L1 APLP2 ORM2 ACTN2 WDR1 TIMP3 P2RX1 SERPINE1 ENDOD1 LHFPL2 CD109 QSOX1	down	*
GSE3982_BASOPHIL_VS_TH2_DN	0.0007244	0.0098885	0.4772708	0.3536091	1.598310	170	TP63 ELOVL6 PROM1 TTF2 TOMM34 ESPL1 SPATS2 DNAI1 HAUS5 SYTL2 AURKA RSRC1 MCCC2 ORC6 ACTL6A CAD INPP4B BLM MTG1 PHB GEMIN4 TMED3 NUSAP1 PSMB5 TMEM8B SPAG5 LRRC42 SNRPE PSMC4 FOCAD VBP1 MRPL11 LRRC8D CENPQ MRPL4 SPA17 SCNN1G SEC14L2 PFAS MED24 CKAP2 SLC41A3 MSH2 DCPS BANF1 DOHH ABCF2 HOOK2 RPUSD2 NDUFA8 SNUPN ADRM1 PFDN4 MTHFD1 TP53 APEX1 SIGMAR1 ADCK2 ENO1 WIZ CHMP6 MRTO4 PRSS50 TOP3A TOMM40 RNF8 KCNK1 TIPIN ZAP70 WNT16 E2F4	up	**
MODULE_8	0.0000156	0.0004086	0.5756103	0.3288020	1.598112	378	HMGA2 TRIP13 FOXM1 LAD1 BUB1B PROM1 CCNB1 CENPF IGF2BP3 PAIP1 PSPH SORD TTK GMPS BAMBI NDUFS6 PLK1 AURKB PTTG1 TPX2 E2F3 CCNB2 MCM2 TYMS UMPS PAH CCT6A SRPK1 SHMT2 ZWINT MYL6B COX11 DNPH1 NUDT1 CHAF1A EEF1E1 TOP2A SEMA6C AGT CBX3 NDUFS2 POLD2 MCM7 CPD PRKDC MRPL3 MCM3 BLOC1S1 LMNB1 AIMP2 SOX4 MDK RBP1 CD24 SLC9A3R1 CDC42EP1 MAD2L1 AHCY PSMD4 CAD ETFA PES1 PON2 TMED3 TMEM106C PLOD2 KRT18 CDK1 SSBP1 FAT1 UCK2 ARPC1A RBCK1 UNG PEG10 FEN1 NUP205 FADD ETFB CBX1 DDT PSMC4 ITPR3 DNMT1 VBP1 ADNP AGL LMNB2 MBD4 COL5A2 ASGR2 TK1 DTYMK DBN1 VIL1 DAP3 ASNS SLC4A2 KRT19 ENPP2 CKAP5 CDC20 IARS2 RPA1 CXCL1 MCM6 KIF21B LSM7 TFAP4 RCC1 PDIA4 SLC1A5 ALG8 EPCAM MSH2 CCNA2 SMARCA4	up	***
GO_LEUKOCYTE_CHEMOTAXIS	0.0001422	0.0025779	0.5188481	-0.3028081	-1.597672	171	CXCL3 IL1A SWAP70 CXCL16 EDNRB IL1B CCL3L1 C5AR1 S1PR1 IL1RN GAS6 IL23A ANXA1 PLA2G7 SBDS ADAM17 JAM3 PDE4D IL10 CCL22 PTPRO BST1 THBS1 CCL3 CXCL2 CCL4 SFTPD XCL2 FCER1G DUSP1 OXSR1 AKIRIN1 TGFB2 NCKAP1L FLT1 IL6 HRH1 RAC2 CCR7 DAPK2 GPR183 CXCL5 CD74 VAV3 ITGA9 FPR2 LGALS3 KLRC4-KLRK1 CCR1 GPR18 ADAM10 PDE4B CCL20 CCR6 CXCR4 KIT EDN1 KLRK1 MTUS1 LYST IL16 ANO6 GREM1 SERPINE1 C5AR2 CNR2 C5 S100A8 PIK3CG CALR WNT5A	down	**
GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP	0.0012735	0.0153194	0.4550599	0.3520496	1.597452	176	CEACAM1 AK4 MCM10 CHEK2 NUP107 DNAJC12 DDIT4 PHGDH TRAIP NUF2 ECT2 GPI CDC25A ALDOC ASPHD2 MIS18A SRPK1 LSM5 CCDC150 EME1 ODF2 KIF2C RRM2 WDHD1 FAM162A BRI3BP RAD18 MNAT1 SLC25A10 PTPN3 POLE2 GMNN DNA2 MRPL17 NARF PA2G4 RNASEH2A HSPA4L POLR2H FANCG TUBG1 FAH MLF2 LMNB2 TK1 GEMIN5 POLD1 SASS6 PSMB3 HNF1B RPRD1B ACLY PFKFB4 ATAD2 PRMT5 FAM3C VDAC1 RFC5 HK2 FARSB SEC13 SCOC WDR76 ADRM1 DHRS3 ZBTB32 NSUN7 NCAPD3 MSRB1 ENO1 C4orf46 TIPRL	up	*
GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN	0.0048756	0.0419498	0.4070179	0.3730835	1.597431	111	ATP10B TICRR SIX4 TTK ANLN EIF2B5 LAMP5 PROC ECT2 CUEDC1 GAPDH SPATS2 XPNPEP1 RANBP1 POLA2 CLSPN SMYD2 RAD54L ANKRD13B EGFR PDZK1IP1 TBC1D8 DSCC1 PERP CAD THOP1 TNFRSF21 PODNL1 EFTUD2 TSNAXIP1 NHLRC1 PSME2 CCDC159 FAM71F2 CDC42BPG LRRC15 GNAL CES4A TTC12 TXNL4B SYBU APBA2 COX5B PGAM1 UQCRQ	up	*
LENAOUR_DENDRITIC_CELL_MATURATION_UP	0.0011549	0.0142137	0.4550599	-0.3196587	-1.597316	107	STAC PPARG FABP4 CAT LIPA LPL CITED2 CD1C GAS6 DNASE1L3 CYB5A ACOT2 ABCG1 RNASE1 TFRC APOC1 FABP5 CCL22 PTPRO CEBPA CCND2 DUSP1 INHBA HLA-DQA1 CCR7 CD83 SERPINB6 PKD2 CD74 CR1 DUSP5 CD86	down	*
MIR6804_3P	0.0036350	0.0338035	0.4317077	-0.3428788	-1.597190	78	DNAH17 PPP4R1 MOB1B EDEM1 CACNA2D2 SDE2 REV3L PPP3CC LDHAL6A PTPN12 SCP2 SOCS2 PDE8A C9orf72 MBD2 NCOA1 CCDC3 ETS1 MAP4K4 ATXN1L KLHL18 PRKCE YWHAZ ADNP2 TSHZ3 CCP110	down	*
LIU_VMYB_TARGETS_UP	0.0011549	0.0142137	0.4550599	-0.3196087	-1.597066	107	SLC31A2 IL17RB DPYSL2 TRPV2 FYN THAP9-AS1 MED4 PCOLCE2 ABCG2 CSGALNACT2 LHX6 TUBB6 FABP5 KLF11 CLIC4 RUFY3 CRIM1 VCPKMT NCOA1 USP25 EMP3 RPS6KA2 IDS RHOQ ZBTB1 CTNNAL1 BNIP3L HSPA2 MGAT2 CXCR4 ULK2 ICAM3 MMD GRB10 DNAJB5 ETFDH PSIP1	down	*
GSE17721_CTRL_VS_CPG_4H_BMDC_DN	0.0002794	0.0045945	0.4984931	-0.3048448	-1.597008	163	SNX10 PTPRE CLDND1 TXNL1 CDH13 MYD88 PRPF38A DSCAML1 IL1RN IL23A CCNL1 GINM1 TNFRSF8 RAB33B FOXP1 BFAR CLN5 SFRP1 TXN PIP5K1B RNFT1 OSTF1 NFKB1 ATF3 DUSP11 RUFY3 AFF1 TANC1 PI4K2A TDRD7 RPS6KA2 MTMR14 ADRA1A APBB2 GYPC GRB2 CST7 POGLUT1 PIK3AP1 HNRNPD STXBP3 SOD2 PLAA PDE4B IL18 SERTAD1 IER5 TAB2 G3BP2 KATNA1 ZDHHC5 SAMSN1 LDLR SLC22A3 MACROD2	down	**
GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP	0.0006801	0.0094354	0.4772708	0.3537724	1.596658	166	TF KIF20A CDC45 TICRR BUB1B CENPF PBK KIF18B PKP1 CHCHD6 DEPDC1B AGFG2 ASPM NUF2 CDCA8 CDC6 CCNB2 SPATS2 PRC1 TNC LDHB HMMR EXO1 MKI67 AURKA KIF2C RRM2 CDCA5 SGPL1 KIF11 PLTP CDC25C LIG1 MAD2L1 CKAP2L SPC24 KNSTRN CDKN2C C12orf75 ASF1B KRT18 FEN1 TMEM51 OCIAD2 ADAM12 CTSV ALDH7A1 MNS1	up	**
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN	0.0002720	0.0044905	0.4984931	-0.3058311	-1.596487	158	USP12 KLF13 EMP2 CLDND1 NXPH3 CAV1 TSHZ1 IL23A CLCF1 FBXO7 CACNA2D2 LUZP1 TTYH2 NR4A1 IL18R1 ARHGEF2 PDE4D RHOB ZMIZ1 SYNPO PIP5K1B SLC12A4 MVB12B ZADH2 SSH1 MATN2 DSTN HES1 ST6GALNAC6 PDK4 CREM KIF13A IFRD1 UBAC2 PRKCE GRASP FSTL3 TPRA1 PKIA TGIF1 CD86 RGS2 PDE4B CXCR4 TMOD2 ALDH2 AMZ2P1 CYTH1 PAIP2	down	**
GO_CYCLIC_NUCLEOTIDE_MEDIATED_SIGNALING	0.0005441	0.0078784	0.4772708	-0.3159609	-1.596414	125	RAMP3 EDNRB LHCGR ADCY9 GPR65 ADCY4 RAPGEF2 RAMP2 CALCRL ADRA1D ADCYAP1R1 TBXA2R PRKAR1A RXFP1 PDE2A CD36 RAPGEF4 PEX5L ADRB1 ADRB2 PDE4D PTGIR THBS1 PDE3B PTGER3 UBE2B GNAQ GNAI2 PTH1R S1PR4 ADCY2 GPR61 ADRA1A PTGER4 PTGER2 NPR1	down	**
GO_REGULATION_OF_CARDIAC_MUSCLE_TISSUE_DEVELOPMENT	0.0031985	0.0306544	0.4317077	-0.3514004	-1.596142	70	RBP4 BMP2 TGFBR3 TGFBR2 JPH2 TBX2 WNT3A TBX5 MIR17HG RBPJ NOTCH1 CREB1 SAV1 TGFB1 PIM1 MEIS1 MYOCD GATA6 RGS2 FGF2 ARRB2 EDN1 PTEN FGFR1 MIR548C NRG1 ZFPM2 SMAD4 GREM1 MAPK1 NOG EFNB2	down	*
GSE42724_NAIVE_VS_MEMORY_BCELL_DN	0.0002825	0.0046393	0.4984931	-0.3045829	-1.595636	163	PEBP4 EDNRB SGK3 USP12 SNX10 FYN KIAA1109 MSRA CCNL1 ANXA1 GLS HLX BFAR PPP2R2A PPM1K GCHFR PRKD3 DRAM1 CLIC4 SEC24B MGAT4A RBMS1 FRMD4A KLRD1 PINK1 PPP2R5A N4BP1 AFF1 NRBF2 LRCH1 HMBOX1 CPEB4 GLUD1 RCAN1 CD83 YWHAZ NUP153 SAV1 PIM1 GPR84 HINT3 STX12 CLASP2 PGGT1B PDE4B IST1 SETDB2 TPT1 PIP4K2A RIPK2 SREBF2 KATNA1 LDLR SPSB1 RBMXL1 C1QB ZYX FAR1 PPIP5K2 CD69	down	**
GO_GROWTH_FACTOR_RECEPTOR_BINDING	0.0025379	0.0256831	0.4317077	-0.3203954	-1.595364	106	EREG CD300LF IL1A IL1B CDH5 KL FYN FGF10 IL1RN CBL HBEGF ADAM17 ITGA5 MS4A1 GATA3 PDGFA IL10 SDCBP SOCS5 EPGN CNTF AREG IL6 SNX2 GRB2 SNX1	down	*
GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP	0.0010326	0.0130212	0.4550599	0.3491895	1.595201	181	SYT8 GGCT PHF14 SDK2 TSPYL5 MSTO1 FLAD1 IFT27 SRPK1 MAP7 WDR3 PSMG4 ZNF443 SLC25A39 RPAP2 CAD ZNF229 MRPL36 ERC2 DHX33 COA4 METTL3 TNRC18 CDC23 THNSL1 SLC35C2 FANCF WDR53 DNAJA3 PUS1 COG2 ZNF544 CCDC51 MAGOHB NAIF1 PALB2 YLPM1 FAHD1 MGME1 THOC5 DDX23 C1orf109 URB1 ESRRA SUOX DUS2 INTS8 MSH2 PRIM1 DZIP3 MRPS25 VPS33B SEC13 SUPT3H RPUSD2 TARBP2 RELL2 ZSCAN29 TRUB1 TAF4 MRPS26 RANGRF ALKBH2 KIAA0586 RTN4IP1 RCN2 MRPL12 EIF2B1 RBL1 MCEE URB2 GXYLT1 RMI1 TP53RK SWSAP1	up	*
GO_MICROTUBULE_BINDING	0.0004497	0.0067540	0.4984931	0.3434568	1.595003	210	KIF1A KIF12 KLC3 KIF20A MDM1 KIF18B RACGAP1 KIF14 PLK1 GAPDH PRC1 DYNC1I1 KIF27 WDR90 KIF23 KIF15 KIF3B MAP10 KIF2C MAP1LC3C FSD1 HOOK1 KIF11 GAS8 KIF3C CLIP3 SPAG8 PPP5C TRPV4 PSRC1 NUSAP1 KIF5A BIRC5 JAKMIP1 KIF19 KIF2A KIF7 CCDC88C SPAG5 MAST1 SPEF1 VPS41 KIF22 DNM1 KIF21A GAS2 S100A9 MAP6D1 KIF20B POLB TRAF3IP1 FTCD CDK5RAP2 KIF21B EML6 FAM161A KATNB1 SKAP1 HAUS4 NEFH STRBP ALMS1 APC2 JAKMIP3 TUBGCP4 SYBU CCDC181 HOOK2 CCDC88B MARK4 CAMSAP3 CENPE MAP1LC3A GOLGA2 DCDC1 MAP9 DNM1L CLASP1 KIF24	up	**
GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP	0.0003098	0.0050209	0.4984931	-0.3038776	-1.594837	167	RAB11FIP1 DENND5A HHEX FYN LY86 PLEKHF2 WDR74 CYB5R3 ZCCHC2 SLC15A3 BCL2A1 CD1C FRAT1 NFATC3 SH2B3 LAIR1 JAM3 GPM6A KLF4 DENND3 GRK5 SCAF4 SSH1 PER2 NFKB1 TM6SF1 TP53BP2 IL24 SNN INPP5B RNF141 PIKFYVE CD83 REL RASSF2 RUNX3 CD74 SAV1 DCK SERPINB1 MACF1 ATAD2B DIXDC1 SP100 OSER1 CD19 PAK2	down	**
GO_LIGAND_GATED_ION_CHANNEL_ACTIVITY	0.0059841	0.0488159	0.4070179	0.3811644	1.594588	91	GRIK2 GRIA4 CNGA1 GRIN2D GABRP GABRB3 JPH3 CHRNG ASIC1 CHRNA7 GRIN2A KCNJ8 P2RX2 KCNH2 TPCN1 KCNJ11 CNGB1 KCNJ2 GABRB2 KCNJ14 ITPR3 CNGA4 GRIN3B SCNN1G	up	*
ZWANG_DOWN_BY_2ND_EGF_PULSE	0.0004173	0.0063652	0.4984931	0.3416731	1.594581	217	FAM227A VWDE TROAP KIF18B DEPDC1 ZNF138 CDCA2 ZFP62 ANKZF1 E2F8 GTSE1 HILPDA DNMT3B CDCA8 ZNF714 STC2 TIGD1 ZNF117 ZNF283 CCNF ANKRD36B ZNF107 UQCC1 CCDC150 STAG3 DPY19L2P2 CENPL LINC00174 ARMC12 FAM27E3 FBXL8 CCDC136 ZNF587 DET1 PSRC1 CDKN2C ZNF440 KIF5A KCTD7 POC5 SMG9 RN7SL166P ZKSCAN5 FGFR1OP ZNF454 ZNF687 DCLRE1C HDHD3 TIGD6 ZNF37A TP53TG1 HSP90B2P SLX4 ZBTB7B STAG3L4 BRD8 PLD1 C12orf65 CATSPER2 ZNF780B TAS2R31 EPCAM GADD45G DPH5 ALOX12P2 CEP85 CYTH2 AP001372.2 ZSCAN22 SYNRG BCL6 ZNF526 ZNF354B ZNF33A SPATA33 ZNF630 ZNF740 MORN4 IFI44 ZNF678 MFSD9 PEX11A HSD17B7 ZNF805 TRIM59 DCLRE1A WDR89 LRRC37B ZNF30 ZNF429 STAG3L1 TOB2P1 ZNF302	up	**
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP	0.0031272	0.0300672	0.4317077	-0.3320658	-1.594148	90	MNDA SNX10 LY86 SAMHD1 MARCO BCL2A1 IL1RN EOGT SLC11A1 LITAF IL18R1 MSR1 MPEG1 ITPK1 CXCL2 CD53 N4BP1 HLA-DQA1 HCK PROCR CTSS TYROBP ATP11A IRF8 CD74 ORM2 ICAM1 MS4A4A NFKBIA GIMAP4 LYZ CYBA C1QB PTGS1 MT1E	down	*
SASSON_RESPONSE_TO_FORSKOLIN_DN	0.0038420	0.0351837	0.4317077	-0.3421702	-1.594131	81	ACP5 ADCY9 PTPRE RASAL2 TRIB1 RAB33B MAP2K3 DAB2 THBS1 AXL PPP2R5C ACTG2 MAPRE2 PI4K2A ACTR2 STK24 ARL6IP5 MAP4K4 CDK14 FLNC PPP3R1 GEM RAB5A CDKN1C ACTB DAPK1 TLK1 PMAIP1 TUBA1A KIDINS220 AKAP12 CAPZA1	down	*
GO_POSITIVE_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	0.0039949	0.0361780	0.4070179	-0.3421379	-1.593738	78	RBP4 SCIMP PGC IL1B CD36 CLCF1 GATA3 IL18R1 TRAF6 TFRC PTPRC TLR4 FCER1G IL6 CD160 MALT1 TBX21 TNFSF13 CD74 TGFB1 CD81 IL18 NLRP3	down	*
MIR3120_3P	0.0000152	0.0003994	0.5933255	-0.2832629	-1.592932	297	WEE1 GCSAML SECISBP2L ZC3H12C C18orf32 OTUD1 PPP4R1 NEDD4L PRKAR1A MEF2A NR3C1 CYP4Z1 VAPA SPG21 ASAH1 NLK PEX5L EIF4E SRSF2 EPM2AIP1 TCF7L2 RAB14 SLC7A2 TLE4 SORBS1 PPM1K FBXL3 SCAF4 SPAG9 DPH3 RBMS1 ZBTB43 ELMSAN1 ADIPOR2 PEAK1 ZNF706 PDE1C AFF1 EFR3A TGFB2 TMEM9B CREBRF ETF1 GZF1 KIF13A EBAG9 PLEKHA3 SRSF3 SNX29 JPH1 FOXN2 EPC1 MTMR9 APBB2 SKIL IDS FAM43A ATL2 DOCK8 HOMER1 OGFRL1 CEBPZ CELF2 RRAS MAPK8 DAGLA AKIRIN2 PHF3 DPM1 PDE4B MBNL1 ATAD2B RBL2 ACAP2 CXCR4 FBXO30 ARIH1 IPO5 MEX3C G3BP2 SSH2 NPAT CUL3 RAB2B DOCK10 ARPC5 SCAI PAK2 KIF1B ZFPM2 EID1 ELFN1 SLFN11 EPG5 PLAG1 TBPL1 FKBP1B	down	***
GO_MITOTIC_CELL_CYCLE	0.0000000	0.0000006	0.7477397	0.3130963	1.592748	876	HMGA2 CCNO MCIDAS TRIP13 FOXM1 CEP72 SPICE1 BRINP1 KIF20A CDC45 TICRR MCM10 CHEK2 BUB1B NEK2 CCNB1 CENPF STOX1 PBK KIF18B NDC80 PRIM2 BRCA1 TUBB2B TTK GINS1 CDK4 SMPD3 RACGAP1 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN POLE CNTD2 NABP2 STIL MSTO1 CEP70 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 TFDP2 CCNB2 RBBP8 MCM4 PRKCA MCM2 TYMS CDC25A MYBL2 PRC1 XRCC2 ORC1 CCNF DTL CIB1 MCM8 ZFYVE19 NCAPD2 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 WDR62 CASP2 MELK HMMR BTRC SMARCD3 DLG1 NLE1 KIF23 CEP55 FOXA1 MKI67 CUL9 BOD1 CUL7 KIF15 KNTC1 KIF3B BUB1 LGMN TOP2A MAP10 AURKA EME1 ODF2 POLA2 SFI1 TPR KIF2C MCM7 MAD1L1 CENPW POC1A CLSPN RRM2 TTLL12 CDCA5 PRKDC WDHD1 FSD1 TOM1L1 KIF11 GPSM2 MCM3 CDC25C SOX4 EGFR LIG1 EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 MDM2 DSCC1 PKMYT1 FBXL8 BLM PPP5C PML CNOT3 ERCC2 MNAT1 SPRY1 SKP2 RECQL5 PSRC1 PTPN3 INCENP KNSTRN CKS1B AFAP1L2 CDKN2C NUSAP1 ANAPC5 CTDSP2 CDK1 POLE2 CEP97 CENPJ RFWD3 BIRC5 GMNN DIS3L2 E2F1 NCAPG PSMB5 CCNJL TMEM8B DNA2 KIF2A ANAPC7 EZH2 CNOT11 SPAG5 EGF SAPCD2 MTBP PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP KPNB1 CEP63 CCNE1 CEP192 RHOC CDC23 CDK3 TUBG1 DLGAP5 CNOT2 PSMA5 NINL TACC3 RAD9A TUBB2A PSME2 KIF22 HIRA MTA3 TUBA8 AKAP8L FZR1 KIF20B ASNS ANAPC1 CDK13 PSMD2 JTB ATAD5 PPME1 CDC7 CENPK SH2B1 TADA3 CKAP5 PSMB3 CDC20 TUBG2 AAAS GBF1 EFHC1 BCL2L1 RPA1 CHMP4C WNT10B CDK5RAP2 MCM6 DNMT3A CHTF8 STAMBP CENPT PRMT1 CKAP2 MCM5 HAUS6 NEK4 TFAP4 AATF KATNB1 RTKN RCC1 CCNG1 HAUS4 PSMB4 ANK3 CEP152 PRMT5 ESRRB NUP62 CEP85 ALMS1 MSH2 CCNA2 PRIM1 BANF1 RTEL1 ANAPC2 TUBGCP4 CEP164 LPIN1 TUBA4B RAD51 GADD45GIP1 TNKS1BP1 ZWILCH FBXW11 CHMP1A	up	***
GO_LYMPHOCYTE_MIGRATION	0.0036788	0.0340661	0.4317077	-0.3354073	-1.592671	87	CXCL16 GCSAML GPR15 ADTRP SPN CCL3L1 S1PR1 GAS6 RHOA APOD ADAM17 GATA3 CRK CCL22 CCL3 CCL4 JAM2 XCL2 OXSR1 LRCH1 CCR7 GPR183 DOCK8 TBX21 MIA3 KLRC4-KLRK1 ADAM10 CCL20 CCR6 ICAM1	down	*
GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP	0.0001650	0.0029210	0.5188481	-0.3018171	-1.592444	171	SEMA6B CD300LF CD101 SGK3 CPEB2 DPYSL2 TRPV2 LMO2 PRAM1 P2RY13 NCEH1 MAN2B1 ARSB NAAA GM2A RNF144B SPRY2 PDE4D ADAMTSL4 ARL11 PPT1 EPOR DAB2 USP2 CEBPA COTL1 AXL HPSE CD300C SMAD7 CPT1A HEXB CABLES1 CYB5R1 HPGDS RCAN1 SNX1 WDR7 TPRA1 CD34 RUNX3 XYLT1 SORT1 TSPAN14 CCR1 FCGRT RGS2 PLA2G15 GPX3 TNFAIP8 SSH2 ULK2 JMJD1C CYTH1 MMD CAMSAP2 LPAR6	down	**
ATAAGCT_MIR21	0.0037716	0.0347005	0.4317077	-0.3205752	-1.592296	104	ELF2 PLEKHA1 TGFBR2 UBR3 PPP3CA SPRY2 UBE2D3 RHOB RNFT1 PER2 RECK SMAD7 MATN2 CRIM1 CREBRF SRSF3 JPH1 FBXO11 PIK3R1 PELI1 ING3 PBRM1 EHD1 PCDH17 KCNA3 TAGAP STK40 MBNL1 OSR1 TRAPPC8 EPHA4 HNRNPK TIMP3 SKI PURB PLAG1 ZNF654 TRPM7 RNF111 ARGLU1 YOD1 NTF3 YAP1 CBX4 AGO2 FASLG CREBL2 TGFBI UBE4A GID4 PCBP1 NAA50 PDCD4 NFIB CPEB3 SOX5 FCHO2 PAN3	down	*
GSE14415_INDUCED_VS_NATURAL_TREG_UP	0.0010827	0.0135190	0.4550599	-0.3145051	-1.591828	138	CD55 CALCRL CIR1 NR3C1 ZBTB2 ZEB2 LATS2 EIF1 C1orf21 SWT1 RGCC ADRB2 CLK1 FOXC2 NRARP CASP1 COQ10B NKIRAS1 CCL4 DUSP1 DNTTIP2 N4BP2L1 TBC1D4 MRVI1 ZDHHC20 TMEM9B AREG VPS37A CREM NDNF JUNB EPC1 TBC1D12 CD7 EPC2 KLF2 FOXO3 KLRC2 ADPRM CHPT1 ZRANB1 BAZ2B RNF2 GEM YAF2 CDC42EP3 POLR2M ULK2 CD3G DNAJB9	down	*
CTTTGTA_MIR524	0.0000052	0.0001614	0.6105269	-0.2752222	-1.591562	365	IL1A SCN4A USP12 CPEB2 PTPRE DDX6 FOSL1 QKI DYRK1A CDC42 TSHZ1 FRAT1 PDCL ZEB2 PDE2A LRRFIP2 ATP2B1 NFIX CACNA2D2 BZW1 EIF5 RANBP9 NLK FOXP1 ADIPOR1 EIF4E PPP3CA SRSF2 LHX6 NDEL1 HNRNPU TCF7L2 UBE2D3 GPM6A ZMIZ1 TLE4 SRSF5 FAM76A TJP1 SNIP1 SEC24B CEP57 ARL4A SLC6A6 HES1 ADD1 TANC1 CNRIP1 NCOA1 FOXN3 MTPN RBM39 GPBP1 PRKRA ID4 WASF2 CREM DDHD1 APPL1 NXF1 NECAP1 JUN MITF STAT4 CPEB4 ZFP91 GLUD1 CELF1 SKIL SP3 MBNL2 GTDC1 SPRY4 KRTCAP2 YPEL2 HIVEP2 SRSF6 BTBD7 EPHA3 SORT1 PPP2CB HNRNPA2B1 VAV3 ITGA9 BAZ2B SBF2 GNAI1 KHDRBS1 LRRC32 IRS2 PCDH17 CSDE1 KAT2B ADAM10 ETS2 ARPP19 JUND SESN1 INTS6 MIER1 FKBP1A MGAT2 TAB2 FBXO30 HNRNPK TMEM184B SRSF10 KPNA4 PARVA JMJD1C NAA15 IQGAP1 GSPT1 WDFY3 PUM1 SMAD4 PPP1CB KALRN MB21D2 DUSP6 ZNF106 NR4A2 HIPK1 SSB CDC42BPB KMT2E ADAMTSL3 API5 SPTY2D1 LAMTOR5 MTSS1 UBE2N TSC22D2 SERP1 ARHGEF12 ATP8A1 RNF111 NR5A2 CPNE2 DACT3 NR4A3 IRX5	down	***
BAELDE_DIABETIC_NEPHROPATHY_DN	0.0000022	0.0000762	0.6272567	-0.2736944	-1.591330	397	CD55 PHYHIP RDX BMP2 FYN LPL ST3GAL6 CITED2 ELF2 DYRK1A PRKAR1A NR3C1 TGFBR3 NEDD9 OTUD4 NFATC3 TMX4 APOD ANXA1 SEMA3B SERINC1 LITAF TMEM123 HNRNPDL MCL1 PDGFA HMGN1 SYNPO TLE4 BIRC2 HNRNPA3 PTPRO CASP1 YBX3 ACSL3 TMED5 GRK5 MYO1B RBMS1 CXCL2 VIM PAPSS1 AXL IGFBP2 ACTR3 EPS15 DUSP1 N4BP2L1 DSTN N4BP1 PAFAH1B1 CALM2 MAFF CRIM1 EFR3A PTH1R SACM1L CLIC5 KANK1 FRY BCAR3 NEK7 MAGI2 AQP3 PNMA2 RHOBTB2 DDX17 DNAJA1 VPS26A RCAN1 PTGER4 FERMT2 PODXL STX7 MORC3 ATP13A3 AP3B1 YWHAZ GPRC5A TOM1L2 PLCG2 CD164 NAPG ALDH3B1 MYL12A CR1 MME PPP2CB KIAA0232 NAB1 GALC ATXN1 TOB1 NPTN SPOCK2 PDE4B PHLPP2 HSPA2 PDLIM5 NBN CDC42EP3 CEBPD CDKN1C HSP90AA1 SP100 MEGF9 BCAM ULK2 OSER1 HNRNPC GLUL ACADM DNAJB9 CAMSAP2 TLK1 EIF4A2 EID1 FNBP1 ARHGEF18 ABI1 VPS13D UBR2 CDC14A SERPINE1 PEX14 GHR EXPH5	down	***
GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP	0.0003226	0.0051734	0.4984931	-0.3031784	-1.591168	167	SLC47A1 CYP27A1 USHBP1 GREM2 SH2D3C KANK3 CRY2 CDH13 GAS6 IER2 CD36 TBX2 KCNK3 BTG2 HLX LAIR1 SLC25A37 CD93 TCAP PDGFA PER3 NPNT FUT7 STK17B CLDN5 ATG7 NR1D2 PTPRC SELL TEF CPT1A KLRD1 PEAK1 ADD1 TMEM9B MYLIP S1PR4 STAT4 IRF8 PALMD PELI1 ICAM2 NKG7 SERPINB1 ZBTB11-AS1 GABARAPL1 DOCK6 SLC2A9 PALD1 CD19 CD3G ABCA8 IL16 CEND1	down	**
PAL_PRMT5_TARGETS_UP	0.0013859	0.0163078	0.4550599	0.3500435	1.590968	178	TRIP13 HELLS PRIM2 TTK CDK4 RACGAP1 AURKB ECT2 NNT CCNB2 FIGNL1 UHRF1 MCM4 MCM2 TYMS NME1 NDUFB8 KIF23 MKI67 GCAT KIF11 CDC25C TOPBP1 AHCY INCENP CKS1B ANAPC5 POLE2 DTD1 GMNN PSMB5 CPNE1 TACC3 SNRPA TUBB2A SPTSSA GAS2 ANP32E PKP4 NDUFA13 NUP85 PTN CDC20 HAUS6 SRSF1 MARCKS U2AF2 INTS8 B9D1 PRIM1 ECH1 RFC5 ECHS1 WLS AURKAIP1 APEX1 SLC38A4 PTOV1 MRPL20 MRPL48 RCBTB1	up	*
GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP	0.0002324	0.0039051	0.5188481	-0.2973051	-1.590726	186	PLEKHF2 CTSW BMPR2 SLC39A8 ARL8B IL1RN FAM49A TMX4 UBR3 CACNA2D2 ASAH1 PBX3 KLF10 GRN CRK ZEB1 ARHGEF2 ATP6V1H REST PRKD3 KLF9 GAPVD1 SNIP1 MGAT4A NFKB1 CDS2 ELK3 HTT UBASH3B PAFAH1B1 SIAH1 FAM102B NCKAP1L SGK1 RNF141 NOTCH1 PIK3R1 GFPT2 BLOC1S6 NUP153 TSC22D1 NAB1 CD86 TAGAP GNA13 CSNK2A2 KAT2B TSPO BMP2K CDC16 TIAM1 PTCH1 MAP3K4 NPAT FNIP2 RORA IQGAP1 TOX2 DNAJB5 TMEM30A SVIL DYNC1I2 PLEKHA2 XRN2 MTSS1 FNDC3A POLR2B WDR26 C15orf48 CBFB PGF ALDH3A2 GSN BICD2	down	**
GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP	0.0003194	0.0051380	0.4984931	-0.3002140	-1.590525	173	CXCL3 IL1A SIGLEC16 SOWAHC IL1B MIR22HG PID1 TMEM138 SLC39A8 NCF2 HPS5 RFTN1 ACER3 PPM1N ASAP1 MTF1 TNIP3 SLC7A11 BTG3 TXN CD58 PTPN12 PLAUR SOCS2 P2RY2 CXCL2 IRAK2 CCL4 FCER1G N4BP1 PIK3R5 TP53BP2 HCK PROCR SOCS3 MAML2 PLEKHA3 HRH1 HIC1 MN1 TREM1 PLK3 ELOVL7 ACKR3 PSTPIP2 FSD1L CXCL5 TNFRSF9 PXK AZIN1 GSAP FPR2 GPR84 SOD2 KYNU CCL20 ICAM1 TNFAIP8	down	**
GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN	0.0003259	0.0052119	0.4984931	-0.3001607	-1.590243	173	USP12 HVCN1 PGC RUNDC3B HSD17B11 CALCRL S1PR1 NR3C1 TGFBR2 ARHGAP29 SH2B3 BTG2 ABCG1 BFAR CLK1 ZYG11B CDADC1 FOXO1 TCP11L2 ID3 MARVELD1 NR1D2 SELL FRMD4A AFF3 SNN RPL17 BTG1 UTRN SH3BP5 RABGAP1 SKIL RC3H1 CD7 CEBPZ LETM2 FOXO3 MTMR2 ZBTB11-AS1 CLCN6 IER5 IQSEC1 SSH2 ABI3 JMJD1C ACADM SKI TLK2 CAMSAP2 SPATA5L1 ZBTB40 REEP1 SETX CDKN1B CNR2 FAM8A1 KBTBD11	down	**
GO_G_PROTEIN_COUPLED_RECEPTOR_ACTIVITY	0.0000664	0.0013666	0.5384341	-0.2882414	-1.590188	240	FFAR4 HCRTR1 GPR17 RAMP3 GPR15 EDNRB PPARG F2RL3 LHCGR P2RY1 GPR65 RAMP2 HCAR2 CCRL2 INPP5K CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 SSTR1 FZD4 NMUR1 ADRB1 ADRB2 GPBAR1 GPR4 TAPT1 PTGIR TACR2 PTAFR NPR3 P2RY2 GPR85 PTGER3 GPR157 PTH1R S1PR4 HCAR3 GPR61 TAS1R1 HRH1 ADRA1A GPR141 PTGER4 CCR7 ACKR3 GPR183 PTGER2 NPR1 SUCNR1 OGFRL1 GPRC5A TPRA1 GPR37L1 GPR3 CCR4 FPR2 NLRP6 GPR84 MRGPRF CCR1 OR52B6 GPR18	down	**
MCBRYAN_PUBERTAL_BREAST_4_5WK_UP	0.0004178	0.0063682	0.4984931	0.3394245	1.590039	224	LTF TSPAN8 CEACAM1 PRLR TP63 PLAT SCIN LAD1 PROM1 WFDC2 SLC2A1 LCN2 IGFBP6 SPP1 COL7A1 SOX9 STC2 ALDOC TNC MANSC1 FOXA1 TPBG SOX4 PFN2 MDK RBP1 CD24 RIPK4 HEBP2 PDZK1IP1 PROM2 SPINT1 PERP EHF DDR1 GRHL2 MBOAT1 WWC1 MARK1 TMED3 CXCL14 KRT18 ESRP1 GDPD1 MKRN1 FEN1 IRF6 PIAS3 ST14 KIF22 ENAH GALNT3 KRT19 EPB41L4B FXYD3 TMEM30B PLEKHB1 MARCKSL1 PTN ERBB3 ABCC3 KRT8 BTN1A1 NHSL1 CDCP1 CDH11 EPCAM SPON2 CDH1	up	**
GSE3982_DC_VS_TH1_DN	0.0014081	0.0164724	0.4550599	0.3498062	1.589890	178	ABCC2 ASB4 CENPF POLQ PBK PMS2P5 CENPA PTTG1 SFXN1 CCNB2 STC2 TYMS ORC1 GINS4 AGK CLDN1 HMMR BUB1 AURKA KIF2C PASK CHAF1B CHEK1 DNAJC9 THYN1 PERP PARP1 DNAH6 BIRC5 TESC RBCK1 FGFR1OP UNC45A HSPA4L DLGAP5 PINLYP PRMT7 FKBP14 MAGOHB COX10 SUPT16H YLPM1 TWIST1 PELO MYO5C THOC5 PRMT1 PRODH PIP5K1A DOLPP1 LSM4 ATAD2 GLO1	up	*
MIR4718	0.0038389	0.0351696	0.4317077	-0.3355871	-1.589679	83	GATA2 PLEKHA1 VAPA ZEB2 SLC3A1 TM2D3 HECW2 BTG2 HIPK3 CAMTA1 GPBP1L1 EIF4E LAMTOR3 TJP1 FAM49B ZBTB43 MBD2 ARHGEF10 RGS13 KLB HIVEP2 MMP15 NPTN SESN1 MGAT2 TIAM1 SIK3 MEGF9	down	*
GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	0.0006277	0.0088517	0.4772708	-0.2994686	-1.589529	180	SASH1 SOX18 LRRC8C GIMAP8 CDH5 RASAL2 AKAP7 ESAM CASP12 GIMAP6 SLCO2A1 AGPAT4 FAM49A PEAR1 ERG ARHGAP29 LUZP1 ABCG1 KANK2 TCF7L2 CYP4V2 GPR4 CSRNP1 PRKD3 MPL ITIH5 AXL CCL4 CCND2 PPP2R5C AFF3 PROCR CREBRF FRY RNF149 PHTF2 UTRN SH3BP5 EPC1 APBB2 GRASP COBLL1 CLN3 FOXO3 ZFAND6 GIMAP1 TCF4 NR2C1 TSC22D1 TSPAN14 DOK2 SESN1 GIMAP5 TBC1D1 NHLRC3 TTC28 SPOPL FNBP1 MAP4 EXPH5 MAMDC2 PLEKHA2 CSNK1G3 PTGS1 C11orf54 IRF1 RCBTB2 TRIM25 FCHSD2 CEP68 PKD1 ARHGAP30 LRRC28 ST3GAL1 MYLK MFHAS1 ZFHX3	down	**
GO_REGULATION_OF_PRODUCTION_OF_MOLECULAR_MEDIATOR_OF_IMMUNE_RESPONSE	0.0029568	0.0288286	0.4317077	-0.3159568	-1.589379	111	RBP4 HMOX1 SCIMP PGC IL1B CD22 CD36 CLCF1 GATA3 IL18R1 TRAF6 TFRC IL10 PTPRC TLR4 FCER1G SMAD7 TGFB2 IL6 CD160 MALT1 TBX21 TNFSF13 TREX1 CD74 TGFB1 CD81	down	*
MIR1271_5P	0.0000090	0.0002553	0.5933255	-0.2774227	-1.589342	323	SLC24A4 AJAP1 EPAS1 COL25A1 NOVA2 SLC12A6 ATXN3 RAB3C ST6GALNAC3 RUNDC3B TMEM170B PTPMT1 CAV1 CORO1C VAT1L QKI CTDSP1 PRKAR1A ERG EDEM1 SLC44A2 HBEGF CACNA2D2 RAPGEF4 EIF5 LCP1 CLN5 SLAIN2 PPP3CA ZEB1 TCF7L2 TAPT1 MAP2K3 AGO4 PRDM16 FOXO1 KIAA0513 TRIM46 ZFAND5 SLC7A8 STK17B MYRIP FAM49B DOCK9 PTGER3 RNF139 PIK3C2A OXSR1 PAFAH1B1 NUS1 LRRC3 TLL1 CNOT6L TOPORS MCMBP SPIN1 VAMP3 NEK7 APPL1 RAB8B MITF VAT1 SH3BP5 C20orf194 PCGF5 PRKCE GRB2 FAM43A STX5 RALB PPM1F MORF4L1 CD164 PTP4A1 FOXO3 EPHA3 SORT1 AZIN1 ABHD13 FEM1B CBFA2T3 MAP3K2 RELL1 ATXN1 PPP3R1 RGS2 NRN1 ARPP19	down	***
GO_REGULATION_OF_CELL_CELL_ADHESION	0.0000032	0.0001049	0.6272567	-0.2792949	-1.589105	341	TNR SIRPB1 SWAP70 CCM2L ADTRP CD55 SPN IL1B WNT4 RDX BMP2 FYN CD44 CAV1 MYADM CITED2 PRKAR1A CDC42 CD9 IL1RN TGFBR2 IL23A RHOA ANXA1 MIR146A SH2B3 CD5 ADA FOXA2 MAP3K8 HLX PAG1 GATA3 SIRPA RGCC TRAF6 WNT3A TFRC NODAL ZMIZ1 IL10 NRARP DUSP3 DENND6A PTAFR KLF4 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SFTPD SMAD7 IL7R UBASH3B HES1 GNRH1 NCKAP1L CD80 IL6 CD160 ETS1 PDE5A PODXL CCR7 PIK3R1 CD83 GRB2 MALT1 RC3H1 DOCK8 AP3B1 FSTL3 TBX21 TIGIT PPM1F PELI1 MBP RUNX3 CD74 TGFB1 CD1D ZBTB1 CD6 YTHDF2 LRRC32 MIA3 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1	down	***
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_UP	0.0003818	0.0059585	0.4984931	-0.3034891	-1.589026	166	CXCL3 EREG IL1A IL1B AQP9 CDH13 SLC15A3 BCL2A1 AGPAT4 IL23A SLC7A7 MTF1 TNIP3 PTX3 NDEL1 BTG3 TFRC TXN ATP6V1H PPP3CC IL10 PLAUR MYO1B NPR3 PDE8A CXCL2 CCL4 UXS1 INHBA MAFF IL24 CRIM1 SNN NINJ1 FLT1 IL6 SOCS3 ETV3 STAT4 CUL4A HRH1 PLK3 WTAP LYRM1 ATP13A3 CXCL5 ACSL1 UBB RIN2 EHD1 SERPINB1 FPR2 SOD2 ETS2 CCL20 TRAF1 PLGRKT MAP3K4 DNAJB9 MT2A FLT4 ARFGAP3 PMAIP1 MYH10 CYB5R2 YRDC HEY1 MT1E LAMP3 GPR137B SLC43A3 CFLAR PTGS2 PCID2 EBI3 DUSP2 MT1X ST3GAL1 TNFRSF1B SLAMF7	down	**
GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN	0.0002264	0.0038162	0.5188481	-0.2988234	-1.588996	176	CXCL3 IL1A ZC3H12C GPR65 CITED2 BCL2A1 KLF6 PAG1 NR4A1 NFE2L2 CST3 RHOB IL10 AHNAK ID3 ERP44 RBMS1 CXCL2 KCTD20 UBE2B DUSP1 PI4K2A VWF RBM39 SLC8A1 SGK1 NEK7 HMBOX1 ATP11A FOXN2 GSTO1 PTGER4 IFRD1 STX5 ATP13A3 CGGBP1 CDK14 AGFG1 GPR37L1 PELI1 DDX18 EHD1 TGIF1 FPR2 SBF2 TSC22D1 FEM1B TMEM230 BRI3 STX12 ATAD2B BMP2K RNF138 TRAF1 KPNA4 OSER1 MCOLN2 ZFAND2A SMAD4 BMI1 EGR1 ZBTB16 CLEC4E SLC38A2 NOG EFNB2 FXYD5 SNX14	down	**
GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN	0.0014505	0.0167789	0.4550599	0.3593927	1.588752	143	MCM10 CDC6 TYMS CDC25A MYBL2 PLEKHA7 DTL ZWINT CASP2 C19orf48 MYO10 E2F2 RRM2 CDCA5 CHAF1B LMNB1 CHEK1 SLC25A10 SKP2 PPIL1 KCNE3 AAGAB GMNN ADAP1 DHX33 FEN1 COA4 CHCHD3 TELO2 CCNE1 SCLY MRPL11 ESCO2 GINS2 GEMIN5 CENPM RRP9 MRPL24 CKMT2 PPCDC GINS3 RCC1 NEFH STRBP ZNF93 DENR AMDHD2 ZWILCH WDR76 SNRPC MRPL48 CYB5B RFFL PPP2R5E TMPO TIMM10 NPM1 WDR5 RMI1 TIPIN	up	*
WELCSH_BRCA1_TARGETS_DN	0.0021573	0.0227477	0.4317077	0.3673407	1.588648	120	DDX11 CDK4 NPIPB3 MCM2 EIF3B SRPK1 CHAF1A PHKG2 AIMP2 SOX4 EMG1 CAD ALG3 SSBP1 AP3D1 ATIC TRAP1 MRPS12 DDT DNAJC7 CCNE1 PDCD11 LMNB2 SSRP1 MLEC CLTA POLD1 SLC1A3 RABEPK RCC1 SLC1A5 FARSA CKAP4 SMARCA4 HDLBP GTF3C2 VDAC1 BMS1 SNRNP70 UBAP2L MTHFD1 NMT1 APEX1 CDC25B SF3B2 POLRMT SRM HRAS SAFB EDC4 GCSH NDRG1 SEC24C XRCC5	up	*
OISHI_CHOLANGIOMA_STEM_CELL_LIKE_UP	0.0000935	0.0018212	0.5384341	0.3327901	1.588645	304	PRLR ONECUT1 HKDC1 HABP2 DGCR9 NUDCD3 PHGDH GAL3ST1 MRPL46 NOL12 SPP1 SAYSD1 NNT PMS2 GON4L TOP3B ZSCAN2 DNPH1 XPNPEP3 BPHL AGT WDR3 NDUFS2 HOOK1 SETDB1 ZNF146 ANKEF1 ZNF226 MORC2 CDC42EP1 LRRC37A4P TBC1D8 ZNF507 MRPS30 ZNF587 PARP1 GEMIN4 EFCAB11 NRSN2 ZNF480 ZNF45 VN1R1 GMNN SCTR BPGM POLR1C SNRPE PRKAA2 ZNF623 VPS72 KLHL22 ZKSCAN5 IMPG2 ZNF692 RANGAP1 ZSCAN9 INTS7 SMG5 NFS1 EFCAB2 YIPF3 COG2 SPTBN5 SPTSSA PPOX ENAH MEGF8 SLC22A5 TRIM32 COX10 RMND5B PROX1 PGBD5 HNF1B IARS2 MAN2A1 ZNF202 MRPL24 ZNF432 SRPK2 ANXA9 HEATR1 ZNF749 SCYL3 TBC1D16 AATF PIP5K1A ZSCAN16 PATZ1 PMS2P1 ZNF224 ZNF212 SCNM1 LPGAT1 FBXW11 SRP9 PTPRF UBAP2L TP53 PRPF3 PCBD1 TIMM44 CLASP1 MZF1 ZNF562 POGZ CSTF1 RNF14 EIF2D METTL18 MRPS16 MLH3 TRIM52 SFT2D2 GPR75 DEPDC5 KIFAP3 MRPL2 GCC1 CRYZ PRCC MTR KLHL12 DGCR2 NDUFB2 MCCC1 FGF1 CTPS1 TMEM183A MIEF1 ZNF473 WDR12 ITPA SUCO SDHC KLHL20	up	**
GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP	0.0004977	0.0073285	0.4772708	-0.3046884	-1.588427	156	ABHD5 SNX10 CD44 MYADM SYS1 FAM49A ZEB2 LRRFIP2 ANXA1 C1orf21 SERPINB9 DACH1 LAIR1 IL18R1 MPHOSPH6 SRGN BAG1 CST3 AHNAK CASP1 YBX3 COQ10B ITGAX NR1D2 HOPX CCL4 PRF1 SMNDC1 INSL6 CALM2 GABARAPL2 IFNGR1 COBLL1 TBX21 CST7 NKG7 KLRC2 SMPDL3B GSAP DUSP5 GABARAPL1 PHF11 ACADL NPTN RGS2 GEM IL18RAP ARHGAP18 GTF2F2 RORA THEMIS2 PMAIP1 CX3CR1 ITGB1 ZYX S100A8 MICAL1 SPTY2D1 UBE2N S1PR5 ATP2B4 NFIL3 ATF6	down	**
GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN	0.0014524	0.0167937	0.4550599	0.3494622	1.588326	178	FOXM1 TICRR TROAP BUB1B TTK RACGAP1 E2F8 CCDC14 POLE PLK1 CDCA8 FIGNL1 THTPA PRKCA XRCC2 TMCC1 ZFYVE19 GINS4 WDR90 CCDC77 EME1 MCM7 CDCA5 RAD54L PASK HEBP2 PDZK1IP1 ORC6 CKS1B CBX5 PPIC POLE2 CCDC61 CENPJ C1orf112 SPAG5 TTC23L TRAF5 DIAPH3 FANCG OR10AD1 FANCF RHBDD3 KIF20B CCDC51 POLD1 ATAD5 PALB2 CENPM FAF1 CKAP2 TDP1 NFE2 PSMB4 STK39 MSH2 LRP11 PRIM1 DZIP3 RFC5 TPGS2 MCU	up	*
GSE3982_MAST_CELL_VS_TH2_UP	0.0004575	0.0068475	0.4984931	-0.2991640	-1.588216	174	TBX3 FBP1 TIE1 EMCN PLEKHF2 PCOLCE2 IL1RN FRAT1 TGFBR2 CD36 ANXA1 ASAH1 PTX3 CAMTA1 SPRY2 CLK1 SPI1 ATP6V1H SORBS1 BST1 ZCCHC24 CPVL ITM2B DAB2 ARNTL TPP1 SOCS5 CLIC4 NPR3 GMPR PAPSS1 DSTN AFF1 LMBRD1 TMOD1 CYB5R1 HERC1 ZNF804A WDR7 ZNF175 GSAP AP1G1 KIAA0232 ZFYVE9 GNAI1 GALC HBP1 CCDC68 ABI3BP SERINC3 DOCK6 EPN2 GLUL TIMP3 TMEM87A TTC19 DNAJB9 SAMSN1 COL13A1 GRB10 EMC3 LYZ KLC1 PHYH CRTAP	down	**
LET_7F_1_3P	0.0000000	0.0000009	0.7477397	-0.2608324	-1.588050	624	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
LET_7B_3P	0.0000000	0.0000013	0.7337620	-0.2607506	-1.588046	623	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP	0.0003388	0.0053980	0.4984931	-0.2997415	-1.588022	173	KMO OLR1 GAPT TMEM170B LYL1 CITED2 SPG21 SIRPB2 RAP1A PBX3 CSGALNACT2 LINC00909 MPHOSPH6 FBXL5 HMGN1 MTMR6 PLEKHM3 CD302 PINK1 SLC6A6 CDKN2AIP NCOA1 GZF1 CDC40 GABARAPL2 HECA PHF10 DDX17 TMEM251 PTGER2 ATP13A3 TUBGCP3 ZCCHC9 ZBED5 NDUFV2 GAS2L3 ATG2B MILR1 METTL14 IRS2 TBRG1 CD81 BRI3 KYNU SERINC3 BNIP3L CPQ FGF14-IT1 RTN1 DOCK10 PAIP2 TRAPPC11 SPOPL ZBTB44 CENPC MAPK1 ITGB1 FBXW2 PPWD1 HMGB1 PAXBP1 KLHL9 WDSUB1 PDPN SDCCAG8 DOCK5	down	**
DURCHDEWALD_SKIN_CARCINOGENESIS_DN	0.0000833	0.0016555	0.5384341	-0.2908703	-1.587667	231	RAB11FIP1 SLPI HMOX1 FCN1 FABP4 CAT CD44 CCDC88A SAMHD1 DDX6 QKI STX11 SEMA6D ASAP1 UBL3 GM2A RANBP9 ABCG1 HIPK3 KLF6 NFE2L2 TIPARP ADARB1 PTPN12 CSRNP1 LRRC57 KIAA0513 PIP5K1B TPP1 CADM1 SMAD7 CLIP4 PEAK1 N4BP1 UBASH3B SNN PIAS1 CD80 CCNY CDC40 BCAR3 PDE6B ESD UTRN AQP3 HPGDS CPEB4 MAP4K4 EEA1 DAPK2 COBLL1 SERPINB6 ATP13A3 YWHAZ RALB DEDD PXK SNX9 FOS AGPS TMX3 IRS2 C16orf72 APLP2 MACF1 ARAP2 CREBBP RAPGEF3 MAFK ZDHHC5 RNF38 KIF1B CAMSAP2 NRG1 PMAIP1 RAP1GAP UBAP1 CLIP1 TMEM43 HMGCS1 FHOD1 DCUN1D3 ITGB1	down	**
GO_SMOOTH_MUSCLE_CELL_PROLIFERATION	0.0013445	0.0160042	0.4550599	-0.3154107	-1.587390	121	EREG HMOX1 PPARG CALCRL CDH13 S1PR1 HMGCR MIR27B TGFBR2 TRIB1 APOD HBEGF FOXP1 TRAF6 TCF7L2 CNN1 IL10 PTGIR PTAFR KLF4 THBS1 NPR3 ABCC4 CDKN1A ID2 GNAI2 IL6 JUN NPR1 SOD2 NQO2 MYOCD FGF2 IL18 SF1 EDN1 FOXJ2 PTEN PRKG1	down	*
GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP	0.0007816	0.0104957	0.4772708	0.3516899	1.587387	167	CCNO B3GALT5 FUT6 CDC45 GABRP EPN3 DEPTOR PBK NDC80 DNMT3B COL7A1 ESPL1 CUEDC1 SLITRK5 MCM2 TYMS COCH DTL INTS1 CEP55 ITGB4 SAE1 E2F2 ERAL1 SMYD5 RIPK4 SLC9A3R1 B3GNT3 TRMT2A GNPDA1 PML GEMIN4 NUSAP1 CBX5 FBXO41 ZNF500 PIAS3 PELP1 COG2 KIF22 SPTBN2 CCDC51 KRT19 MADCAM1 SPINK5 NSD1 LRRC14 BCL9 APOBEC2 TSC2 ANAPC2 ERBB2 UBAP2L ZNF142 PNKP CENPE IDUA MRPS27 FAM222B TRPC4AP MED16 GLI3 RUSC1 CNKSR1 KHDRBS2	up	*
MIR101_3P	0.0000022	0.0000762	0.6272567	-0.2741052	-1.586578	394	AJAP1 SEMA3G SGK3 TAL1 HVCN1 CPEB2 EMP2 CDH5 ZBTB34 CALCRL ZCCHC2 CIR1 KCNN3 TGFBR3 TET2 OTUD4 USP47 UBR3 SH2B3 ASAP1 PLXNA2 PBX3 RANBP9 NLK FZD4 REV3L SPIRE1 ZBTB21 HIPK3 KLF6 CAMTA1 SLC7A11 PPP2R2A ADRB1 SLAIN2 NFE2L2 AKT3 ZEB1 PDE4D NPNT ZSWIM6 PRKD3 TJP1 CEBPA SOCS2 SOCS5 ZNF24 FMNL3 SSH1 MGAT4A COTL1 NR1D2 GPR85 C9orf72 PNRC1 CXXC4 DUSP1 PAFAH1B1 DEGS1 ZDHHC20 SACM1L ARHGAP17 MOB4 CREBRF SLC25A3 SGK1 PHACTR2 NEK7 MAGI2 PIKFYVE CNTN3 MITF NOTCH1 TBC1D12 ATXN1L PRKCE FRYL KBTBD8 MORC3 FOS CTTNBP2 KLF2 PPTC7 TSHZ3 RIN2 ING3 AP1G1 PDS5B MTMR2 CD86 TBRG1 ATXN1 APLP2 MBNL1 ATAD2B INO80D ARAP2 OPN3 EPN2 IQSEC1 RAB5A ARHGAP18 UBE2D1 PTCH1 ZDHHC21 MAP3K4 CUL3 PDE4A RNF38 RORA NAA15 C1orf52 SHISA6 PURB ENY2 EVI5 PIEZO1 DMXL2 JDP2 KCNJ6 ZNF385B ATP11B SLC19A2 MAPK1 ANKS1A NDFIP1 ATP1B1 CCNT2 ADAMTSL3 PPFIA1 CHAC2 UTS2B GABPB1 DR1 PIP5K1C FNDC3A SMARCA5 RNF111 KLHDC1 WWTR1 RAB1A ROBO2	down	***
REACTOME_SIGNALING_BY_GPCR	0.0000003	0.0000121	0.6749629	-0.2607876	-1.586259	534	FFAR4 RBP4 CXCL3 HCRTR1 GPR17 RAMP3 CXCL16 GPR15 EDNRB GPIHBP1 CD55 F2RL3 LHCGR WNT4 ADCY9 P2RY1 GPR65 ADCY4 HSD17B6 RAMP2 GPC5 TRPC3 ARHGEF15 LPL PDE1B HCAR2 CCL3L1 RGS9 CCRL2 CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 PRKAR1A CDC42 RXFP1 PDE4C HSPG2 RHOA PDE2A ANXA1 RLBP1 SSTR1 HBEGF WNT2B GNGT2 FZD4 NMUR1 ABHD6 ADRB1 PPP3CA GNG7 ADRB2 AKT3 WNT3A ARHGEF2 GPBAR1 PDE4D CYP4V2 PPP3CC RHOB GPR4 ROCK2 ARRB1 PTGIR CCL22 DGKE TACR2 PTAFR ROCK1 GRK5 PDE8A CCL3 PDE3B P2RY2 CXCL2 ARHGEF26 CCL4 PTGER3 XCL2 GNAQ PIK3R5 GNAI2 PDE1C PTH1R GNRH1 RPS6KA2 WNT9A S1PR4 HCAR3 PPP2CA METAP1 ADCY2 PDE6A PDE6B RGS18 TAS1R1 DHH HRH1 ADRA1A ARHGEF10 PTGER4 CCR7 PIK3R1 ACKR3 PRKCE GRB2 GPR183 CREB1 PTGER2 RPS6KA1 PRKACA SUCNR1 CXCL5 RGS13 GPR37L1 CALM1 PRKCG DGKG DAGLA WNT11 CCR4 PPP2CB VAV3 FPR2 GNAI1 SLC24A1 GNG5 GPR84 PPP3R1 GNB4 CCR1 GNA13 OR52B6 RGS2 GPR18 GRK4 PDE4B QRFP CCL20 CCR6 OPN3 HTR6 ARRB2 TIAM1 CXCR4 LRP12	down	***
GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP	0.0030323	0.0293950	0.4317077	0.3605367	1.586128	134	CDHR2 SLCO5A1 CYP19A1 LAD1 AK4 GRIN2D RBBP8NL PRSS2 BRCA1 GAL3ST1 IGKV4-1 SIX1 EFNA5 NUB1 TMEM41A MUC6 IDO1 REC8 IFI44L PASK CC2D1A WWC1 STAT2 TNPO2 ZNF827 ZGPAT DTX2 MC1R CADM4 SPTBN2 TMEM30B MDGA1 USP18 DGKA LRRC17 GNG4 PARP14 MMP24 CES4A ADCY1	up	*
IVANOVSKA_MIR106B_TARGETS	0.0032870	0.0312978	0.4317077	-0.3398953	-1.585669	79	SIK1 SFR1 HPS5 NCEH1 KLF10 BTG3 FBXL5 EFCAB14 CYBRD1 TBC1D9 KIAA0513 CDKN1A NKIRAS1 UXS1 CLIP4 TMEM9B JAK1 TNFRSF10B DEDD PKD2 PKIA ZFYVE9 CDC37L1 PLSCR4 DAZAP2 RNH1 PURB TRIM36 CFL2 AKTIP MAPK1 CLOCK	down	*
GCATTTG_MIR105	0.0010278	0.0129798	0.4550599	-0.3096326	-1.585323	146	PDE1B NEDD4L GPCPD1 TEX2 TRA2B BMP1 FOXJ3 CRK TIPARP DENND6A ITM2B COQ10B TJP1 SOCS5 SNIP1 GPR85 CXXC4 PRICKLE2 TM9SF2 KIAA0408 SMNDC1 COPS4 NCOA1 LIN54 MYLIP RYBP GABARAPL2 CCDC3 CELF1 SP3 CELF2 CDK14 YTHDF3 AKIRIN2 MAP3K2 PPP3R1 PCCA PRDM8 SLC31A1 EPHA4 HNRNPK KPNA4 COPS8 FAM126B RAB2A MIER3 EIF4G2 KALRN CDKN1B DCUN1D3 CMPK1 RB1CC1	down	*
GO_POSITIVE_REGULATION_OF_CELL_ADHESION	0.0000062	0.0001853	0.6105269	-0.2782692	-1.585230	343	SIRPB1 LIMS2 FOXF1 TEK CD55 IL1B WNT4 EMP2 FYN CD44 BAG4 CAV1 MYADM CITED2 CDH13 CDC42 MIR27B NEDD9 TGFBR2 IL23A RHOA CD36 ANXA1 CD5 ADA FOXA2 ITGA5 MAP3K8 HLX GATA3 PPP3CA SIRPA TRAF6 CRK SFRP1 WNT3A TFRC FOXC2 NODAL ZMIZ1 IL10 NPNT DENND6A LIMS1 PTAFR ROCK1 STX3 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SMAD7 IL7R HES1 TGFB2 NCKAP1L NINJ1 CD80 IL6 CD160 UTRN NDNF ETS1 MAP4K4 PODXL CCR7 PIK3R1 CD83 PRKCE GRB2 MALT1 HSD17B12 DOCK8 AP3B1 FSTL3 PPM1F RUNX3 CD74 VAV3 CD1D ZBTB1 CD6 CD86 PDCD1 CD81 KLRC4-KLRK1 SPOCK2 ABI3BP UNC13D ICAM1 IL18 ARPC2 EPB41L5	down	***
GO_CELL_PROJECTION_ASSEMBLY	0.0000082	0.0002357	0.5933255	0.3216199	1.584817	465	CCNO PKHD1 MCIDAS ONECUT2 ONECUT1 CCL19 CEP72 CEP89 RPGRIP1L ZMYND8 NEK2 AVIL NUDCD3 RAB3IP MKS1 CCDC113 STK36 IFT122 RHOV SPAG17 ANLN TENM2 TTC26 CEP70 PLK1 IFT27 KIF27 DCTN2 WDR90 EPS8L1 DNAI1 HAUS5 CEP250 RSPH1 PPP1R9A ARMC4 GOLPH3 BBS1 SPAG16 F2RL1 FOXJ1 TSGA10 KIF3B CCDC13 FBF1 MYO10 ODF2 SFI1 IFT43 CD2AP POC1A HYDIN TEKT2 WNT1 CCDC114 DCDC2 PFN2 WDR60 NME5 DNAH8 SLC9A3R1 CDC42EP1 IFT172 GAS8 KIF3C CBY1 DNAAF3 RABEP2 C2CD3 CCDC40 MYO1A TNIK DRC1 LRGUK LRRC6 IQCB1 CDK1 CROCC CEP97 CENPJ VANGL2 TCTN2 SSX2IP DYNLL2 POC1B DNAH5 TMEM231 FGFR1OP IFT52 CEP63 BBS5 PLEKHM1 CEP192 NPHP1 TUBG1 DNAH7 CCL21 MTOR NINL MNS1 CCDC151 IQCG TMEM237 SPAG1 TEKT3 TWF1 NUP85 TRAF3IP1 DNAJB13 SH2B1 C15orf62 CKAP5 IQUB PLD1 WDR34 TTLL3 TCTN1 CDK5RAP2 ODF2L PLEK2 DNAI2 WDR35 HAUS6 DYNC2H1 FAM161A TBC1D30 PIP5K1A HAUS4 RSPH4A NEFH TCHP UNC119B CEP152 TMEM17 B9D1 ALMS1 DBNL MIEN1 ICK CEP164 CLUAP1 DNAH1 MARK4 CELSR2 CTTN TBC1D32 TTC39C VDAC3 NTN1 BCAS3 RHOD UBXN10 CELSR3 ESPN SYNE2 TRPM2 TTC30B ZMYND10 NLGN1 CLASP1 KIF24 LPAR3 KIAA0586 CEP290 ARMC2 DNAAF1 INPPL1 DYNC1H1 MAK TEKT1 ABLIM3 WRAP73 WDR63 PLK4 HRAS FAM110C AKAP9 PCNT	up	***
GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_DN	0.0014605	0.0168723	0.4550599	0.3467072	1.584316	182	HELLS RUVBL1 CHCHD6 MRPL46 CCT2 RANBP1 C19orf48 NLE1 QTRT1 WDR3 POLD2 WDHD1 AIMP2 SLC25A39 TRMT2A EEFSEC SNAPC4 MTG1 MRPL36 HDGF CCT3 GMNN ZMIZ2 E2F1 MRPS2 ANKRD26 LIPT2 UQCC2 PA2G4 TELO2 POFUT1 EXOC7 PDCD11 PUS1 SNRPA UROS COPS7B METTL22 GK5 POLD1 COX10 ELAC2 PFAS PPHLN1 ROMO1 CAPRIN2 LSM7 NEK4 NEURL4 RCC1 ABCD4 C1orf122 SF3A2 TSR1 LRRC14 DCPS MRPL55 PCBD2 CLUAP1 ZSCAN22 ACP1 DTNBP1 SMPD4 PPP1R14B PCTP GEMIN2 POLRMT SHQ1 EIF2B1 CAMK2G SDHAF1 OPA1 URB2 DHRS4 SHMT1 HDAC3 HNRNPAB NCOA5 LRPPRC TP53RK BNIP1 DHPS	up	*
GO_RENAL_SYSTEM_PROCESS	0.0031015	0.0298873	0.4317077	-0.3310651	-1.584180	89	EDNRB ADCY9 EMP2 ADCY4 INPP5K PRKAR1A GAS6 CYP4A11 RHOA KCNMA1 PTPRO RRM2B NPR3 AQP4 WFS1 GNAI2 ADCY2 SGK1 AQP3 ADRA1A NPR1 PRKACA SUCNR1 MCAM IGKV3-20 CD34 SLC4A5	down	*
GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY	0.0006657	0.0092898	0.4772708	-0.3044289	-1.584145	159	SMAD6 ACVRL1 CDH5 ENG FOLR1 CAV1 CITED2 TGFBR3 CBL TGFBR2 RHOA LTBP4 ADAM17 NLK CAV2 ZEB1 NODAL PRDM16 SDCBP NPNT DAB2 THBS1 CLDN5 SMAD7 VEPH1 HTRA4 MIR17HG TGFB2 NRROS ADAMTSL2 APPL1 JUN LTBP2 FERMT2 SKIL CREB1 FOS UBB TGFB1 PARD6A ZFYVE9 TGFB1I1 LRRC32 MYOCD LTBP1 SMAD2 LDLRAD4 ARRB2 CDKN1C CREBBP ING2 SKI LTBP3	down	**
MCCLUNG_CREB1_TARGETS_UP	0.0044868	0.0394933	0.4070179	-0.3437582	-1.583812	74	OSBPL1A BDNF CDH13 IDI1 LMNA BZW1 KLF10 ASH2L ADARB1 AQP4 ID2 CPLX1 HSPA1B ACKR3 HSD17B12 CAP1 CDK14 FOS	down	*
CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_DN	0.0011139	0.0138210	0.4550599	-0.3138774	-1.583753	126	SMAD6 SLPI TSPAN4 RBMS2 SNX10 EMP2 LPL SAMHD1 CITED2 INPP5A MSLN CD9 MAN2B1 ASAH1 IFI30 FOXP1 SPTBN1 ID3 MAP1LC3B GRK5 ATF3 RECK PER1 DUSP1 VAMP5 PEF1 SOCS3 SEC14L1 LAMB2 NOTCH1 ATP11A CD151 FOS KLF2	down	*
GO_RESPONSE_TO_IONIZING_RADIATION	0.0032525	0.0310382	0.4317077	0.3646793	1.583748	123	HMGA2 EYA1 TICRR CHEK2 BRCA1 TSPYL5 DNMT3B NABP2 ECT2 FIGNL1 XRCC2 CXCL10 TP53BP1 RHNO1 BRAT1 ATR PRKDC RAD54L FANCD2 TOPBP1 RAD51AP1 MDM2 BLM PML PARP1 RFWD3 XRRA1 STK11 NET1 INTS7 DCLRE1C RAD9A FBXO4 POLB BCL2L1 DNMT3A XRCC4 UIMC1 VCAM1 MSH2 RAD51 TNKS1BP1 PAXIP1 SWI5 TP53	up	*
GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN	0.0002107	0.0035798	0.5188481	-0.3001492	-1.583643	171	RAB11FIP1 OSBPL11 MYADM FGR DNASE1L3 KIAA0355 DPEP2 SH2B3 GM2A JAM3 HNRNPDL HNRNPU ITSN2 ARL11 RAB14 KPNA5 DENND3 RBMS1 PTPRC ACTR3 SNN SERTAD2 IL6 WASF2 SNX29 CELF1 CCDC50 IFNGR1 DHX15 EEA1 IRF8 GMFG PRKCE FRYL FAM43A UVRAG KLF2 MBP XYLT1 HSF5 ADPRM RPL21 GNB4 ANKRD13A MBNL1 CCR6 ARAP2 OPN3 SIK3 TOB2 HNRNPK TLR10 CEPT1 PTEN	down	**
GO_EPITHELIAL_CELL_APOPTOTIC_PROCESS	0.0046067	0.0402307	0.4070179	-0.3326670	-1.583442	86	HMOX1 TEK GATA2 SFRP4 RAMP2 ECSCR BMPR2 GAS6 TGFBR2 GATA3 RB1 RGCC NFE2L2 TCF7L2 IL10 THBS1 MIR24-2 WFS1 IL6 CD160 NDNF SRSF6 SPOP SORT1 ICAM1 ARRB2 BOK STK4 ANO6 SERPINE1 HIPK1 ZFP36 PIK3CG	down	*
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	0.0005618	0.0080875	0.4772708	-0.3097509	-1.583346	141	FFAR4 HCRTR1 GPR17 EDNRB F2RL3 P2RY1 GPR65 TRPC3 ADRA1D TBXA2R ANXA1 HBEGF GNGT2 NMUR1 ABHD6 GNG7 GPR4 DGKE TACR2 PTAFR GRK5 P2RY2 XCL2 GNAQ GNRH1 RPS6KA2 RGS18 HRH1 ADRA1A PIK3R1 PRKCE GRB2 CREB1 RPS6KA1 RGS13 DGKG DAGLA FPR2 GNG5 GNB4 RGS2 QRFP	down	**
MIR4650_3P	0.0057283	0.0473096	0.4070179	-0.3144469	-1.583336	112	SLC6A4 TRIM71 OLR1 GAPT LRRC8C SLC39A8 FUCA1 PDE2A CD36 UBL3 WNT2B PPP1R15B SDE2 CLEC14A AKT3 TCF7L2 ARRB1 FMO2 ZFAND5 STX3 DENND3 C1QTNF7	down	*
MIR12133	0.0000094	0.0002649	0.5933255	-0.2773442	-1.583165	320	SLC24A4 AJAP1 EPAS1 COL25A1 NOVA2 SLC12A6 ATXN3 RAB3C ST6GALNAC3 RUNDC3B TMEM170B PTPMT1 CAV1 CORO1C VAT1L QKI CTDSP1 PRKAR1A ERG EDEM1 SLC44A2 HBEGF CACNA2D2 RAPGEF4 EIF5 LCP1 CLN5 SLAIN2 PPP3CA ZEB1 TCF7L2 TAPT1 MAP2K3 AGO4 PRDM16 FOXO1 KIAA0513 TRIM46 ZFAND5 SLC7A8 STK17B MYRIP FAM49B DOCK9 PTGER3 RNF139 PIK3C2A OXSR1 PAFAH1B1 NUS1 LRRC3 CNOT6L TOPORS MCMBP SPIN1 VAMP3 NEK7 APPL1 RAB8B MITF VAT1 SH3BP5 C20orf194 PCGF5 PRKCE GRB2 FAM43A STX5 RALB PPM1F MORF4L1 CD164 PTP4A1 FOXO3 EPHA3 SORT1 AZIN1 ABHD13 FEM1B CBFA2T3 MAP3K2 RELL1 ATXN1 PPP3R1 RGS2 NRN1 ARPP19	down	***
GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0006890	0.0095218	0.4772708	-0.3075770	-1.583072	151	SLPI SGK3 KCNA2 TRPV2 PDE1B SAMHD1 IL1RL1 FAM49A STARD9 HBEGF RAPGEF4 ZDHHC2 SPIRE1 ANPEP STOM SLC25A37 ITSN2 MSR1 MEFV TCP11L2 FAM49B SELL ARHGAP9 FRMD4A CD300C CLEC9A PEAK1 HES1 MOB3A PRCP TMEM9B PHACTR2 HCFC2 SLC14A1 ETS1 PODXL COBLL1 CDK14 KLF2 YPEL2 SORT1 TFEB ZBTB1 CD81 KYNU CALHM2 BRWD1 SOAT1 TTC32 MBD5 TMEM109	down	**
GSE27786_LIN_NEG_VS_NKCELL_UP	0.0013579	0.0161003	0.4550599	0.3517615	1.582587	164	CEP72 BDH1 CCDC34 C12orf66 EIF2B5 DIO2 CCNF KIAA0895 CCDC150 KNTC1 FBF1 NUP155 METTL7B SAE1 SYCP2 GPSM2 MORC2 TOPBP1 BACE2 PPP5C PES1 CDK1 CENPH C1orf112 LRRC42 DIAPH3 PPP1R36 OR10AD1 MGMT DAP3 RHD RPRD1B IARS2 SIRT4 SRRT WNT10B MGME1 ODF3B NOB1 LANCL2 PRODH CREB3L2 RHOBTB1 STRBP FARSA BLVRB MLLT1 AGBL5 SMPD4 ZNF205 PWP1 MRPL48 NUP93 GSDMC CLNS1A PDXP ZDHHC13 HRAS PCNT ADSL ZNF771 FOXRED2 TEFM AP1B1 LRP8 AP2A1 TIPIN TXN2 DTX4 TIMM9 SLC28A3 INTS9	up	*
GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_DN	0.0020091	0.0215213	0.4317077	0.3678122	1.582263	114	AK4 SLFN13 ANKFN1 CHRNG IFT27 SAMD15 H19 SLC4A8 CLDN1 NLE1 TIMD4 PMS2P4 KLHDC7A CACNA1G MPHOSPH9 TOM1L1 LINC00857 FAM151A NEK11 C7orf50 FDXR MIPOL1 LINC00894 SLC25A13 FAM205A RTP4 ANKRD45 TBX1 ZNF233 CCDC130 HECTD1 PROCA1 TMEM72 ZNF436 DLEC1 CAPN10 KCNQ3 VWA1 TONSL IGLV3-19 TRUB2 PCGF6 DHX57 AKAP9 TLE2 RAG1 DCAF4L1 DHX32 SOCS2-AS1 CACTIN ZNF17 FGF1 DPYSL3 PACRG	up	*
GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_DN	0.0023765	0.0244451	0.4317077	0.3626350	1.582181	126	PKHD1 LAD1 DCST1 CBY3 SOX2 MUC16 GUCY2C MRPL46 ASPM ANKRD22 RAB36 DPYS TMEM184A WDR73 C11orf16 SARS2 PLXNA1 EHHADH AFAP1L2 MEA1 KCNE3 TNFRSF25 SYN3 BPGM COL3A1 NPHP1 UQCRFS1 VWA5B2 MNS1 NGFR SPAG1 DNAJC11 CLTB ZNF248 NOB1 SIRT5 PKDREJ MYH3 CDH11 PRSS53 TMEM17 BCL9 ALMS1 JAKMIP3	up	*
GSE14350_TREG_VS_TEFF_UP	0.0004788	0.0070908	0.4984931	-0.2980395	-1.582090	178	SECISBP2L FYN NEDD4L GPCPD1 PLEKHA1 MTMR10 MEF2A C3orf70 TMX4 SLC44A2 ABCG2 CYB5A BTG2 ABCG1 CSGALNACT2 CLN5 CRTAM RAB14 STAT5A ITPRIP CASP1 FBXL3 NKIRAS1 TBC1D4 PIAS1 NXF1 VPS26A ATXN1L CD83 RBM22 DOCK8 SNRK CELF2 MOB1A ASTE1 CDK17 YPEL2 TMEM230 TBRG1 MAP3K2 DBNDD2 ATP9B MEGF9 SSH2 MBD5 SCAI PTEN SKI PUM1 MED17 HERPUD1 CLOCK RNF167 WDR41 CD79B MTSS1 KIDINS220 TRAT1 SLC25A45 RAB11FIP2 ZFP1 SCAF8 GALM TNFRSF1B CSTF2T PHIP	down	**
GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP	0.0003199	0.0051420	0.4984931	-0.3004170	-1.581847	170	LTA4H PTPRB MYADM RTN3 PLEKHA1 VAPA FRAT1 ZBTB2 ABCB1 RAP1A SERINC1 RB1 RGCC HNRNPDL CLK1 UBE2D3 RHOB FABP5 MED11 KLF4 SLC12A4 HNRNPUL2 ARHGAP9 PRF1 KLRD1 NUS1 CNOT6L DDHD1 PPP6C SF3B1 STAT4 CTSZ TYROBP SP3 DDX5 THUMPD1 TPP2 RHOQ ICAM2 CHORDC1 EPHA3 AZIN1 IRS2 ACTN2 RGS2 RNF2 CCR6 RPP30 PIP4K2A HSP90AA1 S100A4 RORA MIS18BP1 RNF13 SNRPG DRAM2 UBE2N BCL10 MATR3 MAN1A1 PAXBP1 MAP3K1 WDR26	down	**
GO_REGULATION_OF_CELLULAR_RESPONSE_TO_GROWTH_FACTOR_STIMULUS	0.0001335	0.0024511	0.5188481	-0.2903522	-1.581471	225	SMAD6 SEMA6A ACVRL1 SOSTDC1 HHEX SFRP4 IL1B WNT4 GREM2 BMPER CDH5 ENG FOLR1 CAV1 CITED2 BMPR2 FGF10 TGFBR3 TGFBR2 TMPRSS6 MIR146A MMRN2 LTBP4 ADAM17 TMEM204 ITGA5 FZD4 CAV2 GATA3 SFRP1 SPRY2 ZEB1 PRDM16 SDCBP NPNT ZNF423 DAB2 THBS1 SMAD7 VEPH1 HES1 HTRA4 MIR17HG NRROS RBPJ MYO1C FLT1 ADAMTSL2 NOTCH1 SKIL FSTL3 SPRY4 UBB TGFB1 TGFB1I1 MYOCD TOB1 NPTN LTBP1 SMAD2 LDLRAD4 FGF2 EPN2 CDKN1C CREBBP ING2 SKI FGFR1 GRB10 SMAD4 SKOR1	down	**
SANSOM_APC_MYC_TARGETS	0.0005340	0.0077605	0.4772708	0.3395084	1.581007	214	FOXM1 TICRR PHGDH METTL1 POLE CENPA LIG3 SHMT2 ZFP64 INTS1 NUB1 NME1 WDR62 SMARCC1 CARD11 QTRT1 POLA2 GTPBP3 MCM7 WIPI2 MCM3 SEC61A1 MCCC2 SOX4 GAS8 PSRC1 THOP1 KNSTRN ING4 CTDSP2 ATIC SSX2IP TRIM7 SAPCD2 ANKRD39 DENND6B TELO2 POFUT1 LMNB2 TUBB2A HIRA DPH2 MYBBP1A GEMIN5 DNMBP SLC1A3 COX10 ABCC10 GTF3C1 HNF1B RRP9 BCL2L1 KPTN NSD1 PIP5K1A LHPP OGFR NTMT1 CDC42BPA TMEM141 WDR4 NUBP2 RASSF4 ZMYND19 BCAS3 EIF4G1 SMPD4 MTHFD1 TP53 SIGMAR1 NELFA DNM1L PIAS4 SART3 ASCL2 TRAPPC6A NPTX2 ROR2 ALKBH2 USP20 MED22 SFXN2 SCRN2 PRPF19 SCAMP4 ATRIP NHP2 NDRG1 CXXC1 SHMT1 TXN2 TP53RK MEN1 LFNG DDX49 SEMA4D ZBTB48 ABCB8 PRRC2C	up	**
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_UP	0.0008558	0.0112920	0.4772708	-0.3012032	-1.580848	165	CXCL3 IL1A DLC1 IL1B TRIB1 IL23A SLC19A3 RAPGEF4 MTF1 TNIP3 PRSS12 PTX3 SLC7A11 BTG3 PTAFR PLAUR SOCS2 MYO1B CLIC4 NFKB1 CXCL2 CCL4 DNTTIP2 INHBA IL7R PRDM5 HCK PROCR NINJ1 HCAR3 CD80 IL6 SOCS3 STAT4 TREM1 DNAJA1 WTAP TNFRSF9 ACSL1 EHD1 SERPINB1 FPR2 DUSP5 EWSR1 SOD2 ETS2 CCL20 ICAM1 HSPA2 TNFAIP8 IER5 MT1M NUP98 TRAF1 MAP3K4 NFKBIA SIGLEC9 FEZ1 DNAJB5 REEP1 FJX1 BHLHE41	down	*
MODULE_126	0.0013306	0.0158720	0.4550599	0.3509869	1.580823	160	FOXM1 BIK CCNB1 CENPF POLQ UBE2T PTPRN2 CDK4 GMPS ASPM TPX2 CMYA5 CDC25A UMPS EIF3B SHMT2 MELK MKI67 BUB1 AURKA SIDT1 PPP5C MGLL CKS1B NCAPG2 MB CDK1 HDGF TNFRSF21 ULBP2 PANX2 E2F1 UNG FEN1 DAP ILF2 EDEM3 ETV4 ANKRD6 IARS2 PRMT1 RCC1 WDYHV1 CCNA2 SLC2A5 NME4 CDK5 CLEC11A SMC2 CENPE TCF3 PAICS TIMM44 APEX1 NOMO1 RCN2 PDXP ITGB5 ASPH GCC2 ADSL CLPP FBXO5	up	*
GO_VASCULAR_PROCESS_IN_CIRCULATORY_SYSTEM	0.0007852	0.0105332	0.4772708	-0.3115394	-1.580756	139	SLC6A4 HMOX1 TEK ACE EDNRB P2RY1 RAMP2 CDH5 CAV1 ADRA1D BMPR2 TBXA2R HMGCR RHOA PDE2A ATP2B1 PTPRM ADRB1 ADRB2 FOXC2 ROCK2 KCNMA1 TACR2 PTAFR ROCK1 PER2 P2RY2 KCNMB1 PIK3C2A RAP1GDS1 KCNA5 SLC8A1 HRH1 ADRA1A	down	*
PRC2_EZH2_UP.V1_DN	0.0025801	0.0259565	0.4317077	0.3546613	1.580542	146	HELLS CDH17 HJURP CDC45 MCM10 CENPF NPAS1 PSPH SCN3A DEPDC1 TTK AURKB ECT2 MCM2 CDC25A MYBL2 CDT1 HAUS5 HMMR KIF15 KNTC1 BUB1 PUS7 RAD54L LMNB1 MST1R OXTR DSCC1 LRRC61 SKP2 PSRC1 THOP1 APLP1 GNB1L DNA2 EZH2	up	*
GTTATAT_MIR410	0.0054217	0.0453481	0.4070179	-0.3455983	-1.580420	72	RDX DPYSL2 CITED2 QKI NR3C1 MOB1B NUMB DACH1 DOCK9 SMAD7 MYLIP FMNL2 RAB8B CPEB4 ETS1 SP3 IP6K1 BAZ2B ANKRD12 MACF1 ADAM10 YAF2	down	*
GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP	0.0003361	0.0053631	0.4984931	-0.3000759	-1.580051	170	SLC16A4 MYD88 RPL23AP53 NR3C1 IL1RL1 RCHY1 RFTN1 IL23A ABCB1 IER2 ZEB2 HBEGF MAP3K8 KLF10 BTG3 PDGFA CD58 ADARB1 FABP5 PPT1 FOXO1 ADO GRK5 ATF3 TAF9 SMAD7 AFF1 RPL17 RBPJ JUN KCTD12 DDX17 IFNGR1 GSTO1 IPO7 CD83 REL TNFRSF9 ACSL1 CDK17 PKD2 STXBP3 TGIF1 CD6 GNG5 GABARAPL1 MACF1 PGGT1B CCL20 GEM ZNF143 SLC31A1 CEP170 SPARCL1 RAB5A TIAM1 DIXDC1 OSER1 MMD ZNF165 PUM1 NR4A2 SNW1 CYP51A1 UNC50 UBE3A TSC22D2 HMGB1 TES ATP8A1	down	**
GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP	0.0002944	0.0048072	0.4984931	-0.2953229	-1.579920	187	CXCL16 MCOLN1 KLF13 DDX6 ZCCHC2 PAFAH1B2 CTDSP1 TBC1D2 CBL FRAT1 GGA2 TXNIP FBXO7 LINC01010 IFI30 ZNF503 BFAR UBE2D3 ARL11 FABP5 REST FKBP15 NUS1 NRBF2 CD300LB PI4K2A STK24 ST6GALNAC6 TMEM9B MED28 SH3BP5 CAP1 KIAA0232 FEM1B DOK2 TMEM70 CCR1 PLEKHO2 TMA7 AMD1 SERTAD1 ELOVL1 ARRB2 BLOC1S2 ACTB SP100 HAVCR2 G3BP2	down	**
YAATNRNNNYNATT_UNKNOWN	0.0055634	0.0463130	0.4070179	-0.3454778	-1.579869	72	SLC24A4 BDNF CDH13 ERG NFIX IFNK LHX6 ZNF423 RBMS1 NPAS3 CCSER2 IKZF5 FOXN3 PDHX CREM MN1 DDX17 CELF2 TGIF1 ELF5 ZDHHC21 MTUS1	down	*
GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_DERIVED_MACROPHAGE_UP	0.0023033	0.0238652	0.4317077	0.3609204	1.579822	128	GABRB3 PRTFDC1 C6orf141 PMS2P5 ASPM C1orf220 BTRC RPAP1 CENPL ZNF766 SYCP2 ANKRD52 RBM28 IL20RB ZNHIT6 XXYLT1 BMS1P1 GET4 HSF2BP C4orf47 NRG4 MYOT PPM1E MCTP2 KCTD7 ULBP2 ANKRD54 SLC35F3 L3MBTL3 ZNRF2P1 DTYMK PLAC4 WDR34 SIRT4 ZNF76 ZSWIM8 TMEM147 LRRC73 AMT TMEM253 LINC00964 TUBGCP4 VPS9D1 PTPRF ENPP5 CHPF2 DCAF11 E2F7 ZNF253 ACTR5 PHRF1 VPS18 PTPRK LOXL1-AS1	up	*
GO_HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES	0.0000002	0.0000078	0.6901325	0.3126838	1.579784	709	KIF1A KIF12 ABCA13 KLC3 DDX11 ENTPD2 ABCC2 HELLS KIF20A DDX12P RUVBL1 CDC45 DNAH2 MYO3B POLQ KIF18B TTF2 MYH16 PIF1 TUBB2B GINS1 KIF14 RHOV ABCA12 GMPS PMS2P5 IFT27 RGS6 FIGNL1 THTPA MCM4 RAB36 MCM2 RAD54B DNAH3 PMS2 XRCC2 DYNC1I1 MCM8 GINS4 KIF27 MYL6B DNAH14 DCTN2 DNAI1 RUVBL2 TNNT2 NUDT1 KIF23 RND2 HLTF KIF15 KIF3B TOP2A MYO10 RAB19 GTPBP3 SMARCAL1 KIF2C MCM7 WDR78 ABCC5 RHOBTB3 HELB RAD54L ENTPD6 KIF11 MCM3 PEX6 PFN2 NUDT17 WDR60 CHD6 DNAH8 MORC2 ABCB6 KIF3C RAB13 DCTPP1 ABCB9 DSCC1 DNAH11 BRIP1 EEFSEC BLM MTG1 RGS4 ERCC2 MNAT1 ENTPD5 MYO1A RECQL5 DDX56 NSF DDX51 DNAH6 KIF5A GBP3 NUDT2 NAV2 DHX37 ABCC11 KIF19 DNA2 KIF2A DHX33 ENPP3 KIF7 DYNLL2 MYO5B RAB6B DNAH5 ABCA4 PSMC4 RECQL4 GBP5 EFTUD2 DHX34 MYO19 MOV10 ARFRP1 RHOC TUBG1 RGS17 RABL2A DNAH7 DHX40 FHIT LONP1 TUBB2A TUBA3D KIF22 RAD51D ARF5 DNM1 TUBA8 CHTF18 GBP6 KIF21A GINS2 NUDT16 KIF20B GFM2 CHD5 GNAZ ENPP2 ATAD5 RAB24 ATP13A1 RAD50 ABCC10 KLC2 KLC4 EP400 LSG1 ABCC9 ENTPD8 WDR34 TUBG2 ENTPD3 ABCC3 ABCA7 FANCM MCM6 CHTF8 MYO5C WRNIP1 DYNC1LI2 KIF21B DHX8 MCM5 DNAI2 GNG4 RAB15 ZRANB3 DDX23 DYNC2H1 RAB3D KATNB1 DOLPP1 MYH7B IGHMBP2 RHOBTB1 MYH3 RAP2B ABCD4 LHPP DDX55 ATAD2 TSR1 RAB34 GNAL MYH13 PMS2P1 MSH4 PMS1 MSH2 SMARCA4 DCPS DDX54 ABCF3 RTEL1 CANT1 RFC5 NUGGC GBP1 GTPBP2 ABCF2 DNAH1 TUBA4B BMS1 RAD51 ARHGAP5 GBP2 SNRNP200 CHD3 GNA14 RHOT2 GNA12 RAB43 RNF213 CENPE RHOD SRCAP MYO15A DDX52 HSPA7 CGN	up	***
GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_DN	0.0016762	0.0186894	0.4550599	0.3478956	1.579732	177	HJURP BUB1B NEK2 NDC80 BET1 RACGAP1 KIF14 ANLN POLE TPX2 PRC1 EIF3B TNC WDR62 CISD1 MKI67 KNTC1 AURKA E2F2 MMS22L CKAP2L URI1 HDGF CENPH C1orf112 TNFRSF25 AAGAB POC5 FEN1 NUP205 SF3B3 SNRNP25 NMRAL1 MNS1 XYLT2 TRIO C15orf41 NADSYN1 TSTA3 CDC20 RRP9 CKAP2 TFAP4 ALG8 ZNF286A RTEL1 FKTN ARHGAP11A RPRD2 NDUFS8 UQCRQ SMC2 NMT1 UBE2C NPEPL1 KCNK6 RPL23A TNFRSF1A VPS16	up	*
GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP	0.0002237	0.0037761	0.5188481	-0.2994026	-1.579705	171	SLC6A4 CXCL3 ABHD5 CLDND1 HSD17B6 SIK1 CDH5 FOLR1 EGR2 NEDD4L QKI PRPF38A CCNL1 EDEM1 SLC44A2 ASAP1 SLC25A17 CLEC7A CSRP1 RANBP9 BFAR GPBP1L1 ZBTB8A PRKD3 SLC7A8 STX3 VRK2 ITGAX ARL4A SPRYD7 PTH1R HEXB PKIG SLC25A25 PHTF2 CTSZ GYPC MSANTD2 NAP1L5 TIMP2 SAV1 NDUFA5 VPREB3 RGS2 ATAD2B NEK1 SLC34A2 NBN CALHM2 TBC1D1 G3BP2 STK4	down	**
GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS	0.0016762	0.0186894	0.4550599	0.3478060	1.579326	177	HMGA2 DDX11 FOXM1 EYA1 PARPBP CHEK2 EYA2 TIMELESS POLQ BRCA1 NPAS2 WDR70 FIGNL1 MAGEF1 TP53BP1 EEF1E1 AUNIP ATR MSX1 SMYD2 PRKDC HELB EGFR CHEK1 RAD51AP1 XRCC1 MDM2 PML PLA2R1 RECQL5 PARP1 RFWD3 MAD2L2 RAD9A FBXO4 MGMT NUDT16 TRIM32 BCL2L12 ATAD5 PARP9 UBQLN4 TWIST1 BCL2L1 UBE2V2 THOC5 WRNIP1 ANKRD1 UIMC1 NEK4 DTX3L RTEL1 RAD51 EYA4 PAXIP1 NUDT16L1 WDR76 SIRT6 PARG TP53 MUC1 PIAS4 TMEM161A	up	*
GO_EXOCYTOSIS	0.0000000	0.0000006	0.7477397	-0.2535201	-1.578717	727	SIRPB1 RAB11FIP1 SLPI FOXF1 HMOX1 FCN1 OLR1 PECAM1 HVCN1 CD55 GATA2 MNDA CLEC3B LTA4H CAT RAB44 P2RY1 CLEC12A RAB3C PTPRB OSCAR MMRN1 CD44 STXBP6 CTSW PRAM1 CHIT1 CYB5R3 VAMP2 PAFAH1B2 C5AR1 YPEL5 STX11 MANBA VAPA CD9 FUCA1 GAS6 LAMP1 CBL SLC11A1 LILRB3 FGR RHOA CD36 ANXA1 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB RAPGEF4 ASAH1 RAP1A GM2A RAB33B ANXA5 ANPEP PRSS12 PTX3 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 SRGN PDGFA RAB14 CD58 CST3 FABP5 CFD RAB12 EXOC3L2 EXOC3L1 SDCBP LIN7C BST1 PTAFR PLAUR REST ROCK1 GAA OSTF1 THBS1 STX3 ATP6V1D FAM49B ABCC4 CTSD ATG7 TMBIM1 CCL3 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL SELP HPSE ARHGAP9 CD53 FCER1G PIK3C2A PLEK GCA GNAI2 DEGS1 ANXA3 BACE1 CMTM6 CPLX1 LIN7A VWF ACTR2 TGFB2 GLB1 HEXB HCK HGSNAT RAB6A NCKAP1L PRCP ARHGAP17 VAMP3 CTSS PSEN1 PHACTR2 NKD2 SNAP23 RAB8B PDCD6IP CYB5R1 VAT1 NOTCH1 RAB31 HK3 CTSZ ADRA1A RAC2 TYROBP HSPA1B ATP11A RHOG ENPP4 GLIPR1 GMFG RAB8A SERPINB6 UNC13B CAP1 RALB TAGLN2 BLOC1S6 CALM1 PSMD12 PRKCG ALDH3B1 BIN2 CR1 MME TIMP2 STXBP3 SIGLEC14 TGFB1 TMX3 AP1G1 DOK3 MILR1 SERPINB1 FPR2 CDC37L1 TSPAN14 MIA3 DYNC1LI1 ATP6V0C GPR84 APLP2 LGALS3 EXOC1 ORM2 BRI3 CCR1 CLASP2 ACTN2 PLEKHO2 ADAM10 IST1 SYT11 COMMD9 UNC13D	down	***
LET_7A_3P	0.0000000	0.0000004	0.7614608	-0.2591992	-1.578628	626	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
GSE10325_CD4_TCELL_VS_BCELL_UP	0.0005992	0.0085348	0.4772708	-0.2978102	-1.578555	181	TRPV2 FYN SAMHD1 SLC39A8 MAL TGFBR3 GIMAP6 ANXA1 STOM GATA3 ZMYM6 RGCC TMEM123 SRGN PDE4D ATP10A ARRB1 LEPROTL1 ARNTL SOCS2 MGAT4A DOCK9 PDE3B VIM ID2 CCND2 PRF1 CCSER2 SH2D2A GNAQ VAMP5 TBC1D4 KLRB1 PHACTR2 IL2RB AQP3 STAT4 PLK3 PIK3R1 PTGER2 CALM1 CD6 PIM1 TOB1 SELPLG WDR1 TIAM1 PIP4K2A GIMAP5 GPD1L S100A4 CD3G DUSP7 RORA CCND3 LPAR6 GIMAP4 TNFSF8 SVIL TMEM43 AKTIP PRKCH ICOS	down	**
GO_TUBE_DEVELOPMENT	0.0000000	0.0000001	0.8012156	-0.2508554	-1.577880	857	SMAD6 TRIM71 ANGPT4 DAB1 RBP4 EPAS1 SEMA6A EREG RAMP3 TMEM100 ACVRL1 IL1A SOSTDC1 SASH1 FOXF1 HMOX1 SLC12A6 SOX18 TEK DLC1 EDNRB TAL1 PECAM1 RASIP1 PPARG ADTRP HHEX TBX3 ROBO4 GATA2 IL1B TIE1 CAT WNT4 EMP2 RAPGEF2 BMPER LIPA RAMP2 PTPRB BMP2 CDH5 ENG FOLR1 ECSCR SOX17 CAV1 CITED2 CALCRL QKI CDH13 BMPR2 GTF2I TBXA2R C5AR1 S1PR1 FGF10 CDC42 MIR27B TGFBR3 TGFBR2 HSPG2 HEG1 RHOA ZEB2 APOD ANXA1 TBX2 MIR146A MMRN2 PTPRM ADA WNT2B RAP1A PLXNA2 ITGA5 CLEC14A HSPB1 LUZP1 FZD4 FOXP1 ANPEP HLX SLC7A11 EIF4E GATA3 NR4A1 JAM3 RB1 RGCC TRAF6 NFE2L2 GRN SFRP1 AKT3 SPRY2 WNT3A ZEB1 SPI1 TCAP MTHFR PDGFA TMEM38B FOXC2 NODAL TIPARP RHOB ZMIZ1 HIF3A GPR4 IL10 ROCK2 AMOTL1 NRARP TBX4 NPNT TNFSF12 TSPAN12 KLF4 ROCK1 VASP THBS1 ADAMTS9 CEBPA CLDN5 CLIC4 SEC24B ITPK1 FMNL3 CDKN1A PDE3B ITGAX EPGN HPSE ID2 MIR24-2 RECK SFTPD PIK3C2A ELK3 WDR48 SMAD7 ADIPOR2 TBX5 SH2D2A NUS1 PTGIS DCHS1 HES1 MIR17HG PLCD1 ANXA3 TGFB2 MMP19 SRF BTG1 PRCP RBPJ GZF1 HESX1 FLT1 AREG IL6 WASF2 PKNOX1 CD160 PSEN1 ADAMTSL2 NDNF HECA JUN NOTCH1 ETS1 CTSZ JUNB JAK1 RHOJ PODXL ATXN1L SP3 ACKR3	down	***
GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN	0.0005052	0.0074177	0.4772708	-0.2972176	-1.577727	178	SLPI ST8SIA6 GLIPR2 SPN CLDND1 THBD INSIG1 MYADM GPCPD1 ZBTB2 IER2 EDEM1 SPG21 RRAGC ASAP1 UBL3 PICALM SRGN COQ10B TMED5 MAFG ERP44 ATF3 UBE2B PLEKHB2 PLEK PI4K2A LIN54 EMP3 SLC25A33 RYBP NEK7 IL2RB VAT1 SH3BP5 JUNB SKIL PNPLA8 TPP2 TBX21 ZCCHC9 ATP6V0D1 PIK3AP1 TGIF1 DUSP5 ATP6V1A CD86 GNA13 SYT11 PITPNA RNF2	down	**
REACTOME_LEISHMANIA_INFECTION	0.0000757	0.0015301	0.5384341	-0.2888202	-1.577705	227	RAMP3 IL1A GPR15 IL1B LHCGR ADCY9 ADCY4 RAMP2 FYN BAIAP2 CALCRL ADCYAP1R1 IGKV1-33 PRKAR1A ELMO1 CDC42 RXFP1 FGR TXNIP DPEP2 IGKV2-28 ADAM17 ENTPD1 GNGT2 ADRB1 GNG7 ADRB2 CRK GPBAR1 TXN IL10 PTGIR MEFV CASP1 NFKB1 ACTR3 WASF3 GNAI2 PTH1R ACTR2 HCK NCKAP1L IGLV2-11 MYO1C ADCY2 IL6 WASF2 JUN PTGER4 GRB2 CREB1 PTGER2 PRKACA IGKV3-20 PLCG2 CALM1 MAPK8 VAV3 GNAI1 GNG5 GPR84 GNB4 IGHV3-23 IGKV1D-39 IL18 ARPC2 HTR6 NLRP3 ACTB ADORA2A CD3G ARPC5	down	**
GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN	0.0004234	0.0064354	0.4984931	-0.2963497	-1.577217	177	EPAS1 HMOX1 EDNRB OSBPL11 ENG MYD88 SLC44A2 ASAP1 ADA MAP3K8 LITAF NDEL1 FABP5 STAT5A TIMM10B CCL22 CASP1 DAB2 ZFAND5 SELP C9orf72 CCL4 CD53 HTT CMTM6 INPP5B RAB8B JUN ST6GALNAC4 MAP4K4 PIK3R1 SNX1 UNC13B TINF2 AGFG1 KRTCAP2 CD86 MAP3K2 PIM1 ATP6V0C CCR1 STX12 TSPO IST1 BMP2K TNFAIP8 CEBPD HSPA8 CTSC MCOLN2 TLK2 NABP1	down	**
GO_AXON_EXTENSION	0.0043964	0.0388982	0.4070179	-0.3182413	-1.577205	102	TNR SEMA6B SEMA3G SEMA6A DPYSL2 TRPV2 BMPR2 SEMA6D SEMA3B TTL PLXNA4 ISLR2 NDEL1 WNT3A TRIM46 C9orf72 PAFAH1B1 RUFY3 SRF LAMB2 IFRD1 RTN4R	down	*
MIR10527_5P	0.0000003	0.0000141	0.6749629	-0.2662961	-1.577040	493	SLC6A4 GCOM1 MS4A7 SECISBP2L MNDA ATXN3 RAB3C KCTD9 CCDC88A LONRF1 CALCRL QKI MTMR10 DYRK1A TET2 PPM1D ACER3 KCNAB1 SSTR1 PTPRM B3GNT5 LATS2 PKD2L2 MTF1 EIF5 PBX3 ZBTB21 FOXP1 HIPK3 KLF6 EIF4E SRSF2 EPM2AIP1 MCL1 RAB14 KDSR MAP2K3 ROCK2 TBC1D9 SCP2 LIN7C YBX3 ST3GAL2 HAUS2 ZFAND5 STK17B THBS1 CEBPA LAPTM5 CTBS CXXC4 LBH CEP57 CCND2 M6PR ZBTB43 ELMSAN1 MBD2 DSTN CLIP4 SLC6A6 PRICKLE2 AFF1 BACE1 CMTM6 C2orf69 LIN54 SNX3 KCNA5 GPBP1 SPIN1 RYBP VPS37A DDHD1 PHACTR2 EBF2 APPL1 RAB8B ZFP91 ADRA1A MN1 MSRB3 CNTN4 SHOC2 RABGAP1 SKIL PCGF5 IDS RC3H1 FSD1L SLC10A7 OGFRL1 APH1B NIPSNAP3B PXK ZNF407 CELF2 CDK14 BLOC1S6 FOS SLC25A24 ADNP2 CTTNBP2 PELI1 CDK17 PTP4A1 HIVEP2 SRSF6 TSHZ3 DGKG PKIA HNRNPD VAV3 ATG2B CCP110 TBRG1 MAP3K2 CSDE1 PPP3R1 MYOCD STON1 SBSPON ZNF267 PGGT1B ADAM10 MBNL1 ARPP19 RXRA INO80D HELZ MIER1 ZNF143 CTTNBP2NL ITPRIPL2 SFT2D1 TBC1D1 POLR2M ZDHHC21 SSH2 PARVA ACADM SCAI FAM126B FGFR1 DOCK4 NRG1 CCND3 GIMAP4 DUT WDFY3 BMI1 DMXL2 ZNF326 HAT1 ABI1 UBE2V1 EXOG CDKN1B TMEM30A HIPK1 ATF2 SLC19A2 MAPK1 CMPK1 CD109 KMT2E PLXDC2 CSNK1G3 DNAJB4 LMO7 PIAS2 SGIP1 UBE3A	down	***
PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN	0.0007584	0.0102390	0.4772708	-0.3063063	-1.576532	151	CD55 HHEX GFOD1 ZCCHC2 NEDD9 CD22 PDE2A LACTB B3GNT5 LCP1 HNRNPDL SLC25A37 UBE2D3 CD37 ID3 ZADH2 COTL1 PDE3B CNOT6L ARHGDIB AFF3 SNN MTPN BTG1 USP25 S1PR4 SH3BP5 ETS1 CCDC50 SNX2 CCR7 STX7 GMFG GYPC FRYL FAM43A WDFY4 CELF2 KLF2 SERPINB1 VPREB3 PDLIM1 ANKRD13A RNF2 TNFAIP8 UBE2D1 GPD1L CD19 STK4 BCAT1 CECR2 BANK1 ARHGEF18 FUS PLEKHA2 EBF1 PAX5 RCSD1 FCRLA SNRPN SMIM4 FAM111A BTBD1 CBFB ANKRD44 PUM2 RDH12 TNFRSF19	down	*
E2F1_Q4_01	0.0005806	0.0083205	0.4772708	0.3442022	1.575819	189	CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A MCM8 EPHB1 RANBP1 WDR62 CASP2 MELK PAQR4 AP4M1 NUP155 POLA2 MCM7 PRKDC MCM3 TOPBP1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 TNPO2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 FANCG INTS7 NDUFA11 DHX40 DNAJC11 RHD KDM3A SASS6 PPP1R8 HMGA1 PELO MCM6 SRSF1 GINS3 OVOL2 STK35 ATAD2 EIF3K PATZ1	up	**
GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_UP	0.0003497	0.0055580	0.4984931	-0.2976709	-1.575369	172	CD52 PECAM1 DDX6 YPEL5 MAL FRAT1 ATF7IP2 DPEP2 MALAT1 PPP3CA AGO4 TLE4 LINC00528 DENND6A LEPROTL1 STK17B ARNTL LAPTM5 NR1D2 PNRC1 SH3BP5-AS1 PINK1 IL7R PIK3R5 CNOT6L C16orf54 ARHGDIB SNN PIAS1 CREBRF KLRB1 UTRN AQP3 AK1 GLIPR1 PIK3R1 HERC1 IDS ENTPD4 KLF2 YPEL2 MBP FOXO3 GSAP TSC22D1 HBP1 GPR18 SPOCK2 SLC35D2 CXCR4 EPHA4 IFFO1 SSH2 CYTH1 ZBTB40 ARRDC2 ARHGEF18	down	**
GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_DN	0.0008707	0.0114415	0.4772708	-0.3123111	-1.575360	131	KRT81 SEMA6B EPAS1 CYP27A1 RAMP2 CD44 RTN3 DDO LMNA EIF1 FOXC2 CYBRD1 MAP2K3 YBX3 PINK1 MATN2 MPC1 CMTM6 SLC25A3 VAMP3 NXF1 RAB31 ATP6V0B PABPC4 SPATA2L MFAP4 BTBD7 SMPDL3B EPB42 SOD2 RGS2 TMA7 DOCK6 PITPNA EIF3F BNIP3L ALDH1B1 PKNOX2 NRG1 DNAJB5 TNFRSF10D RABGEF1 EXOG CHP1 EIF3L AOAH EFNB2	down	*
GO_POSITIVE_REGULATION_OF_TUMOR_NECROSIS_FACTOR_SUPERFAMILY_CYTOKINE_PRODUCTION	0.0039535	0.0359221	0.4070179	-0.3468151	-1.575314	70	SPN LPL IL23A CD36 TNFRSF8 CLEC7A HSPB1 ARHGEF2 PTAFR THBS1 LY96 CCL3 PTPRC TLR4 FCER1G PSEN1 TYROBP IFNGR1 PIK3R1	down	*
GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE	0.0032257	0.0308629	0.4317077	0.3638181	1.575303	119	FOXM1 CHEK2 CCNB1 BRCA1 E2F8 GTSE1 PLK1 TFDP2 ACER2 DTL CASP2 EEF1E1 AURKA ATR MSX1 SMYD2 PRKDC WNT1 CDC25C SOX4 CHEK1 MDM2 PML CNOT3 PLA2R1 ING4 CDK1 E2F1 CNOT11 MAD2L2 CEP63 CNOT2 FZR1 ATAD5 TWIST1 PRMT1 ANKRD1 UIMC1 TFAP4	up	*
GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0010009	0.0127396	0.4550599	0.3489933	1.575088	166	PRLR PARPBP BUB1B ZNF280B MPP6 PHGDH BET1 GINS1 ANLN AP1S1 SHMT2 NCAPD2 ZFP64 CDK5RAP3 EXO1 KCNN4 POLD2 TTLL12 GCAT PKM KIF11 TRPT1 SEC61A1 PYCR2 KDELR2 DSCC1 ALG3 TMED3 CDKN2C UCK2 GOT2 PSMB5 BPGM UBFD1 ST14 ALDH7A1 NMRAL1 SND1 COPS6 CENPK RNF187 MAN2A1 STAMBP PYCR1 ZWILCH SLC12A2 ENTPD7 DNAJC10 NMT1 SRPRB NCAPD3 KCNK6 NCAPH DHDDS TFG EIF2B1 PNPO TM9SF1 PTGR1 TMEM214 ALPK2 TIPIN PLOD3 NUDCD1	up	*
GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN	0.0006079	0.0086393	0.4772708	-0.3006086	-1.574818	157	ACP5 SASH1 LY86 P2RY13 NCF2 CD22 SLC11A1 NCEH1 ADAM17 MS4A14 TTYH2 LAIR1 FOXJ3 PLXNA4 LAMTOR3 TCF7L2 ITM2B ZFAND5 TPP1 MGAT4A FCER1G DUSP1 DSE RUFY3 GZF1 SLCO2B1 SEC14L1 HPGDS CPEB4 HK3 CTSZ TYROBP LPCAT2 ATP13A3 ACSL1 TIMP2 ZFYVE9 SBF2 IRS2 GALC MACF1 ADAM10 SERINC3 PLA2G15	down	**
GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_WOUNDING	0.0051033	0.0435348	0.4070179	-0.3416047	-1.573890	74	TNR AJAP1 ADTRP WFDC1 WNT4 THBD HMGCR CD9 MYOZ1 SH2B3 ANXA5 CRK PDGFA PLAUR THBS1 CDKN1A UBASH3B KREMEN1 RTN4R CD34 EPPK1 CLASP2 FGF2 TFPI EPHA4 EDN1 PTEN PRKG1 SERPINE1 CDKN1B CD109 SIGLEC10	down	*
MIR1275	0.0006852	0.0094802	0.4772708	0.3365564	1.573673	226	ATP10B GRIK2 SPICE1 FOXA3 PCDHGA10 SPOCK1 ASB4 SYNPR IGF2BP3 TNNI1 PCDHGA9 PCDHGA5 PCDHGA7 IP6K3 PCDHGB2 PCDHGA6 UBE2Z PCDHGA1 PCDHGB3 NAALADL2 PCDHGB6 PCDHGB4 PRKCA GUCA1B PCDHGA11 PCDHGA8 PCDHGA12 COPG1 PCDHGC5 PCDHGC4 WDHD1 PCDHGA4 PCDHGB7 PKM PCDHGA3 CCDC148 SPINT1 SLC45A3 ZNF32 DCLK1 C12orf75 PPM1E SDCBP2 KSR2 SSX2IP HMGXB3 PCDHGA2 LAPTM4B COL1A1 NFASC DVL3 PIGG ADAR CADM4 TMTC2 SRGAP1 SPA17 PCDHGB1 SH2B1 HMGA1 FAM50B ACLY	up	**
GSE34515_CD16_POS_MONOCYTE_VS_DC_UP	0.0001679	0.0029646	0.5188481	-0.2947583	-1.573642	185	ACVRL1 LPIN2 FYN LONRF1 AKAP7 BMPR2 SFR1 TEX2 TRA2B CD5 LMNA KLF6 NDEL1 HNRNPDL ZMIZ1 KIF1C ITM2B STK17B FMNL3 PER1 B9D2 PRICKLE2 KPNA3 TP53BP2 NRBF2 LMBRD1 ACTR2 SACM1L MOB4 SAR1A PHTF2 DDX17 JUNB MCM9 FYTTD1 TTC14 IDS ATL2 DYM EPC2 AGFG1 NKG7 RIN2 BAZ2B CEP76 KHDRBS1 NAB1 CSDE1 PPIG CRY1 SPOCK2 SERINC3 MIER1 ABL2 TNFAIP8 ITPRIPL2 HSP90AA1 LYSMD3 FDX1 NFKBIA PRKG1 ANXA11 NR3C2 PPP1CB FNBP1 CHIC2 TMEM30A ZNF800 FUS ITGAL CMPK1	down	**
GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN	0.0007310	0.0099470	0.4772708	-0.2967156	-1.573629	182	ACP5 CXCL16 SGK3 PECAM1 KLF13 GAPT PTP4A2 GIMAP8 ENG SH2D3C MYD88 FUCA1 FRAT1 TGFBR2 TACC1 C1orf162 GRN ARRB1 MPEG1 PTAFR RRM2B MGAT4A COTL1 EVI2A ELMSAN1 PINK1 PIK3R5 STK24 HCK ARL6IP5 SEC14L1 HECA LTBP2 DDX17 RHOG GRB2 RPS6KA1 RASSF2 NDST1 PPM1F RUNX3 PIK3AP1 GIMAP1 TFEB ANKRD13A MR1 GLTP CALHM2 ELOVL1 IFFO1 SIN3A DUSP7 PAIP2	down	**
GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_IL2_CULTURE_UP	0.0006427	0.0090377	0.4772708	-0.3003664	-1.573549	157	IL1B SNX10 CCDC88A MYADM SLC15A3 PILRA ZEB2 PLA2G7 C1orf21 MPHOSPH6 LAMTOR3 ZFYVE16 SRGN PDE4D BAG1 NRARP MPEG1 BST1 COQ10B ITIH5 HOPX ID2 CCL4 PRF1 SMNDC1 INSL6 MTPN AREG CREM SAR1A TREM1 EEA1 LYRM1 COBLL1 NKG7 KLRC2 XYLT1 CHPT1 NAB1 GABARAPL1 PHF11 ACADL RNF2 GEM ARAP2 IL18RAP NFKBIA AIM2 RORA EMC3 EHD4 PMAIP1 SCLT1 TSTD3 NR4A2 CX3CR1 ICOS ITGB1 SH3GLB1	down	**
GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP	0.0014630	0.0168854	0.4550599	0.3488214	1.573233	169	HELLS ELOVL6 TROAP BUB1B XYLB KIF18B CDCA2 ANLN PLK1 CDCA8 ECT2 NCAPD2 TTLL4 C19orf48 KIF23 OSBPL2 AURKA SLC29A2 IDH2 KCNJ2 SKP2 CDKN2C PABPN1 KCNE3 AP3D1 GMNN OAT SLC25A13 EZH2 NUP205 POC1B RNF150 FGFR1OP PLEKHG3 TK1 PKP4 ATAD5 SLX4 NAT9 NR6A1 PFAS CDC20 ACLY ZRANB3 URB1 SLC41A3 CCNA2 TRERF1 DNPEP SNX8 PNKP EIF4G1 FRMD6 TRUB2 KIF24 NCAPH POLRMT USP20 MLH3 CRAT HDAC10 TRPS1 TLCD1 GAK SAFB2 SMAD3 NLRC3 REEP4	up	*
GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_UP	0.0004097	0.0062746	0.4984931	-0.2996961	-1.572892	167	CD55 TTC7B CD44 NEDD4L AQP9 S1PR1 ELMO1 CD9 GNPTAB NFATC3 FAM49A PDE2A ATP2B1 CYP17A1 RAPGEF4 C1orf21 ECHDC1 FOXP1 LAIR1 ZSWIM6 SELL PIK3R5 CNOT6L FRY SH3BP5 ETS1 ELOVL7 CCR7 PIK3R1 FRYL COBLL1 CD7 DYM TAGLN2 ICAM2 BIN2 C19orf38 SMPDL3B VAV3 PDLIM1 ZC3H12D RXRA RNF138 IL18 IL18RAP GPD1L B3GNT2 CYTH1 CCND3 SMAD4 ARHGEF18 TNFSF8 CX3CR1 KBTBD11 FAM53B	down	**
E4F1_Q6	0.0000809	0.0016164	0.5384341	-0.2869550	-1.572620	235	ZMYND15 CXCL16 SECISBP2L KCNA2 RBMS2 SIK1 EGR2 CALCRL CRY2 NR3C1 NEDD9 TRIB1 ZEB2 ZBTB4 EIF4A1 EIF1 C1orf21 ZBTB21 PPP2R2A TOR1AIP1 NR4A1 SLC25A37 SRGN CCNI ZADH2 ZNF24 DPH3 C1QTNF7 KIRREL3 DUSP1 WDR48 SH2D2A PAFAH1B1 CALM2 MAFF FAM76B AKIRIN1 LMBRD1 RAB6A SACM1L NINJ1 GPBP1 ETF1 SLC25A25 DNAJC27 CD160 PPP6C OXNAD1 EPC1 PPP1R15A CREB1 CDK2AP2 STX5 LETM2 MCAM GPR3 PTP4A1 PSMD12 FOSB KAT8 AZIN1 HNRNPA2B1 ATP6V0C LTBP1 GEM NEK1 TNFAIP8 SLC31A1 SEC63 OSR1	down	**
GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_UP	0.0029178	0.0285136	0.4317077	0.3524637	1.572402	151	MUC13 HP SLCO5A1 CNGA1 FOXA3 BIK CEP89 HOXD8 HOXB6 SLC2A1 TBRG4 IQGAP3 TRAIP CHRNA7 PTTG1 FIGNL1 AGR2 FAM220A ITGB4 SYNE4 SMYD2 SNHG11 CDC25C TARS2 SMYD5 KCNJ11 POLR1C MECR ALX4 SLC35C2 ATP9A MBD4 YIPF3 DHODH ASGR2 PTGER1 FHL2 LIPC ENPP2 MAT1A CDC20 FAHD1 TIAM2 EXOSC5 IL7 MMP16 RCN3 TMEM141 GTPBP2	up	*
MIR98_3P	0.0000000	0.0000016	0.7337620	-0.2580841	-1.572185	628	SLC6A4 TRHDE USP12 SECISBP2L SOWAHC CPEB2 EMP2 RDX PTPRE BMPER BTNL9 BDNF SEC22C KIAA1109 CORO1C HEATR5B QKI BMPR2 GTF2I HMGCR NR3C1 TGFBR3 VAPA TET2 OTUD4 SCARF1 PPM1D RHOA WWC2 UBL3 ASAH1 PPP1R15B MTF1 REV3L FOXP1 HIPK3 GLS CAMTA1 PEX5L DACH1 SLAIN2 GATA3 PPP3CA ZMYM6 SRSF2 ADRB2 SPRY2 ZFYVE16 TFRC ATP6V1H RAB14 ZMIZ1 CWC22 MAP2K3 PRDM16 TLE4 FOXO1 SGTB SORBS1 BST1 KLF4 ITM2B ROCK1 ARNTL MED6 GRK5 FBXL3 UBQLN1 C1QTNF7 CADM1 CEP57 ACTR3 UBE2B WASF3 PIK3C2A BRF2 MATN2 PEAK1 GNAQ KIAA0408 KPNA3 HES1 NRBF2 FAM76B RABGGTB EFR3A CNOT6L AFF3 ZDHHC20 PIAS1 STK24 LIN54 USP25 RBPJ CREBRF C5orf58 ID4 CCNY RNF149 PHACTR2 APPL1 PIKFYVE UTRN HIC1 JPH1 C11orf58 BMP3 SHOC2 FOXN2 ELOVL7 FYTTD1 EEA1 MBNL2 MALT1 RC3H1 MSANTD2 RBM22 RNF24 DENND4A GPRIN3 KLF2 HIVEP2 YTHDF3 SLC4A5 TSHZ3 NAA16 FAM204A HNRNPD HNRNPA2B1 VAV3 ISM1 ATG2B DPM1 SBF2 CEP76 TRGC1 LRRC32 GNB4 TOB1 STK40 CLASP2 CRY1 GNA13 RIMKLB ETS2 MBNL1 INO80D ARAP2 RNF138 PDLIM5 SLC34A2 CTTNBP2NL SCN7A RTN1 IER5 ARIH1 PTCH1 NUP98 LYSMD3 FNBP4 CEPT1 MARC1 DOCK10 SCAI PAK2 B3GNT2 TMEM87A CECR2 FAM126B RORA ITCH NRP2 RHOT1 ZFPM2 SFPQ EIF4A2 PUM1 SPOPL RAB2A DNAJB5 ZNF326 YTHDC1 ABI1 PSIP1 COLCA2 PLAG1 DUSP6 CLIP1 DKK3 AKTIP ZNF800 ATF2 CLOCK CMPK1 SRSF11 SV2B TRPM7 UBE2W WAC C11orf54 CTR9 AKAP12 RAD21 MAN1A1 DDX21 PAXBP1 DR1 ARHGAP44 FNDC3A SMARCA5 MEF2D CNTN1 ZFYVE21 WDR26 NR5A2 CPNE2 ITGA6 NKTR RAB11FIP2 EDIL3 NR4A3	down	***
SABATES_COLORECTAL_ADENOMA_DN	0.0001586	0.0028257	0.5188481	-0.2904359	-1.572174	205	TMEM100 FABP4 CLEC3B SLC51B LYVE1 GREM2 RUNDC3B EPB41L3 SEMA6D BRINP3 CD36 LIFR WNT2B ABCG2 ANPEP PAG1 MS4A1 TNS1 SFRP1 CD37 CNN1 GLDN TBC1D9 AOC3 USP2 BCHE ITIH5 JAM2 WASF3 DUSP1 MYH11 CA1 PLAC9 AFF3 TRGC2 FAM107A ADCY2 SYNPO2 PDE6A CNNM2 CD48 KCTD12 BMP3 CNTN4 MFAP4 LGALS2 SIGLEC1 EPHA3 ENPP6 VPREB3 MEIS1 SCARA5 ABI3BP PHLPP2 GPX3 SCN7A LMOD1 RTN1 OSR1 SPIB MFAP5 TMOD2 MT1M DOCK10 MCOLN2 ABCA8 TMCC3 FAM13C	down	**
GO_MUSCLE_STRUCTURE_DEVELOPMENT	0.0000002	0.0000092	0.6901325	-0.2641577	-1.572125	514	RBP4 EPAS1 EREG SOSTDC1 FOXF1 PDLIM2 EDNRB CCM2L TBX3 WNT4 RAMP2 BMP2 SIK1 ENG BDNF EGR2 TMOD3 CAV1 QKI GPCPD1 S1PR1 HMGCR FGF10 PRKAR1A MEF2A CDC42 TGFBR3 CD9 TGFBR2 NFATC3 HEG1 RHOA KCNAB1 JPH2 TBX2 MYOZ1 HBEGF CACNA2D2 LMNA CSRP1 TMEM204 BTG2 CAV2 HLX PPP3CA RBM4 RB1 WNT3A ZEB1 HNRNPU TCAP TCF7L2 SGCA SETD3 FOXC2 ADARB1 UNC45B TNNC1 NPNT BNIP2 YBX3 REST ID3 PLEKHM3 USP2 ARNTL CDK9 SPAG9 NR1D2 ATF3 MIR24-2 CD53 SMAD7 ZMPSTE24 TBX5 VAMP5 CYP26B1 MYH11 HES1 MAFF MIR17HG AKIRIN1 TANC1 TGFB2 LMOD3 PIAS1 MTPN SRF BTG1 RBPJ SLC8A1 CNTF TMOD1 YBX1 MED28 COPS2 UTRN NOTCH1 ADRA1A JPH1 DDX17 FOXN2 EPC1 IFRD1 DDX5 CREB1 HOMER1 ITGA11 FOS CACYBP CD164 EHD2 FLNC SYPL2 SORT1 SAV1 TGFB1 EHD1 MIR23A PDLIM1 PIM1 CD81 SOD2 MEIS1 MYOCD GATA6 ACTN2 RGS2 PRICKLE4 TAGLN MBNL1 RXRA FGF2 IL18 PDLIM5 FKBP1A WDR1 LMOD1 ARRB2	down	***
GO_ALPHA_AMINO_ACID_METABOLIC_PROCESS	0.0025738	0.0259232	0.4317077	0.3502776	1.572023	158	CPS1 GPT GPT2 BHMT ACMSD PSPH NOXRED1 SLC25A21 PHGDH GMPS ALDH18A1 GLDC PAH SHMT2 GFPT1 IDO1 GCAT MCCC2 PYCR2 ASS1 AHCY CAD TST PLOD2 GOT2 OAT PSAT1 HYKK FAH ALDH7A1 ASNS MAT1A NAGS PFAS HPD FTCD SIRT4 PHYKPL ASRGL1 HIBADH PRODH AMT GAD1 DDAH1 PYCR1 AGMAT NOS1 MTHFD1 SEPHS1 PCBD1 BCAT2 ACAD8 SARDH NOS3 HGD ASL MPST PLOD1 GCSH MTR SHMT1 MTRR NIT2 PLOD3 AFMID MCCC1 HAL CARNS1 HAAO	up	*
KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION	0.0004403	0.0066395	0.4984931	-0.2955252	-1.571773	184	CXCL3 ACVRL1 IL17RB IL1A CXCL16 IL1B BMP2 CCL3L1 BMPR2 TGFBR2 IL23A TNFRSF8 CLCF1 LIFR IFNK IL18R1 PDGFA IL10 CCL22 EPOR TNFSF12 TNFSF15 MPL CCL3 CXCL2 CCL4 XCL2 INHBA IL7R IL24 TGFB2 CNTF FLT1 IL6 IL2RB IFNGR1 CCR7 OSM CXCL5 TNFRSF9 TNFRSF10B TNFSF13 CCR4 TGFB1 IFNAR1 CCR1 PLEKHO2 IFNLR1 CCL20 CCR6 IL18 IL18RAP CXCR4 CCR9 KIT TNFSF9 FLT4 TNFRSF10D CSF2 CD70 CSF2RB GHR TNFSF8 CX3CR1	down	**
MCBRYAN_PUBERTAL_BREAST_4_5WK_DN	0.0006583	0.0092054	0.4772708	-0.2987629	-1.571425	164	GPD1 WEE1 EPAS1 FABP4 TIE1 LIPA CDH5 LPL AATK DDX6 QKI HSPG2 CD8A SH2B3 BMP1 MALAT1 KCNK3 GM2A PRELP STOM TNS1 MAPK8IP1 TFRC EPB41L2 KIF1C FABP5 PER3 SORBS1 PPP6R3 ZFAND5 BCHE HLA-DQA1 PDK4 MYO1C PDCD6IP ZFP91 ETS1 PRKCE TPP2 ACSL1 EHD2 EHD1 APLP2 SOD2 SOD3 TMEM109 MARC1 CYTH1 GRB10 ACAT1 NIPSNAP3A ETFDH ATP6V0A1 KLF15 ACVR1C ZBTB16 ZNF106	down	**
MAML1_TARGET_GENES	0.0000680	0.0013969	0.5384341	-0.2885959	-1.571329	223	ARHGAP31-AS1 ZEB2-AS1 GAPT RCOR1 SH2D3C LY86 BACH1 NR3C1 NEDD9 BCL2A1 IL23A LYRM4 DNASE1L3 ZEB2 TXNIP ACOXL CD36 SBDS CYB561A3 MS4A1 TOR1AIP1 ZEB1 RNU2-6P PDE4D CD37 TLE4 P2RX5-TAX1BP3 CCL3 CCL4 CD53 PLEK HES1 RN7SL473P MOB3A MAPRE2 AFF3 SEC14L1 SFTPB CTSZ RHOG IRF8 UBAC2 REL CDK17 USP7 RUNX3 ICAM2 NAPG SLC4A5 PIK3AP1 MME TFEB GSAP TMX3 NAPSB CD1D TESK2 GPR18 SELPLG LDLRAD4 MIR155HG PUS10 SPIB TXNDC11 CD19 GTPBP8 P2RX1 IL16 CYBA JDP2 PRKCH ITGAL HES4 DRAM2 PLEKHA2 CD69 EPN2-AS1 CD79B	down	**
GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_DN	0.0004420	0.0066581	0.4984931	-0.2965272	-1.570993	173	CXCL3 IL1A IL1B ARRDC4 PDE1B CALCRL C5AR1 HMGCR IL1RN TNFRSF8 HBEGF SLC25A17 ITGA5 RBM4 MAP2K3 STAT5A TNNC1 PLAUR ITPK1 PER2 CDKN1A CCL4 PER1 DUSP1 AFF1 MAPRE2 ACTR2 PROCR NCKAP1L RPS6KA2 MYO1C TULP2 SOCS3 SKIL THUMPD1 ENTPD4 TNFRSF9 SNRK RRN3 EHD1 PIM1 TMEM70 STK40 RIMKLB POLK ETS2 IL18RAP TIAM1 TRAF1 NFKBIA GTF2F2 MT2A PSMD9 PIM3 EGR1 SERPINE1 CNR2 HIPK1 ZFP36 MT1E	down	**
GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP	0.0012299	0.0149147	0.4550599	-0.3066505	-1.570055	146	GPR15 HHEX CLDND1 SLC6A12 CCDC88A DDX6 PRAM1 SUSD2 SFR1 AGPAT4 C11orf94 MALAT1 ITGA5 STOM IL18R1 REST UHRF1BP1L DENND3 MGAT4A RIT1 ARHGEF26 FCER1G TM9SF2 IL7R ARHGDIB AFF3 SENP3 CTSS SNAP23 RABGAP1 DOCK8 CD7 CELF2 ACSL1 PLCG2 CD74 ZFAND6 TEC HNRNPH3 MACF1 GPR18 ABI3BP PDE4B CCR6	down	*
GO_REGULATION_OF_CHEMOTAXIS	0.0005778	0.0082895	0.4772708	-0.2957718	-1.570052	178	SEMA6B SEMA3G SEMA6A SWAP70 CDH13 BMPR2 C5AR1 S1PR1 FGF10 GAS6 IL23A SEMA6D PLA2G7 SEMA3B ADAM17 HSPB1 JAM3 PLXNA4 WNT3A DUSP3 PTPRO BST1 ZSWIM6 THBS1 STX3 CCL3 CCL4 XCL2 DUSP1 OXSR1 AKIRIN1 NCKAP1L IL6 NOTCH1 RAC2 CCR7 DAPK2 GPR183 SUCNR1 PPM1F CD74 CCR4 TGFB1 FPR2 KLRC4-KLRK1 CCR1 GPR18 ADAM10 CCR6 FGF2 SEMA4A TIAM1 CXCR4 EDN1 KLRK1 MTUS1 FGFR1 IL16 ANO6 GREM1 SERPINE1 C5AR2 C5 TREM2 EFNB2 CALR WNT5A ANGPT2 HMGB1	down	**
GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN	0.0003529	0.0055986	0.4984931	-0.2934353	-1.570020	186	ST8SIA6 ACE TSPAN4 CD44 SEC22C LONRF1 QKI CTDSP1 HMGCR P2RY13 RFTN1 HEG1 CLCF1 DNAJC3 ABCG1 PAG1 LAIR1 RGCC TXN ZMIZ1 HNRNPA3 PIP5K1B RIT1 PDE3B HNRNPUL2 VIM MPC1 HCK PLEKHA3 SH3BP5 PHF10 CUL4A OSBPL9 RPL9 PI4K2B IDS RBM22 ATP13A3 TRAK2 PPM1F MBP TRAPPC10 STXBP3 SAV1 KCTD10 NFYC CD81 PGGT1B SERINC3 POLK DOCK6 BMP2K B3GALNT1 ATP9B FBXO25 IFFO1	down	**
GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP	0.0015128	0.0173512	0.4550599	0.3512892	1.569743	154	PRR15 TFPI2 FOXM1 NEK2 SLC5A1 GTSE1 UBE2Z TENM2 ASPM AP1S1 CENPA LSR GALNT10 HNF4G SPPL2B DNPH1 TP53BP1 COPG1 CENPL SYNE4 CHAF1B CDC25C CAD REPIN1 PPP5C FLNB NRTN THOP1 ZNF32 POLE2 E2F1 MECR SPAG5 LMNB2 RAD51D TK1 CDC7 KLC2 CENPV TUBG2 RRP9 BLCAP PIGU CACNB3 DOLPP1 PDIA4 PI4KA MRPL55 FARSB STK25 ACP1 ADCY6 CAPN9 NELFA SART1 RAD1 AZGP1	up	*
GO_NEGATIVE_REGULATION_OF_DEFENSE_RESPONSE	0.0005189	0.0075847	0.4772708	-0.2997584	-1.569492	166	FFAR4 SIGLEC11 GPR17 ACP5 FOXF1 TEK PPARG WFDC1 CDH5 SAMHD1 CLEC12B CALCRL APOD MIR146A ADA RNF125 SERPINB9 GATA3 SIRPA RB1 GRN CRK IL10 MEFV KLF4 SOCS5 NFKB1 NR1D2 PTPRC PTGIS SOCS3 SEC14L1 PSMA1 ETS1 PTGER4 CST7 YTHDF3 TREX1 CR1 SMPDL3B FPR2 YTHDF2 NLRP6 CNOT7 SYT11 ARRB2 NLRP3 HAVCR2 ADORA2A RORA ITCH LDLR	down	**
GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN	0.0006694	0.0093369	0.4772708	-0.3020645	-1.569002	160	KMO ARHGAP31 CAT CLEC12A PID1 SLC6A12 SIK1 CAV1 CDC42EP2 PLEKHA1 HEG1 CD36 ADAM17 CYB5A ANPEP MS4A1 SLC7A2 MEFV LIMS1 ZADH2 KLF7 INHBA N4BP1 PIK3R5 SPRYD7 FAM102B PROCR LACC1 CD80 RNF149 STAT4 ETS1 CCDC50 NXPE3 CD83 CST7 KRTCAP2 GSAP NAB1 KCNA3 STK40 PDE4B ICAM1 WDR1 NLRP3 TRAF1 NFKBIA SAMSN1 ATF4	down	**
GSE22886_IL2_VS_IL15_STIM_NKCELL_UP	0.0034821	0.0328387	0.4317077	0.3565202	1.568996	133	ATP6V0A4 PTPRZ1 EGLN3 ASB4 DGCR9 GUCY2C ABCA12 PCDHGB6 SEC14L5 THTPA SGK2 INSRR SCG5 ITGB4 HAVCR1 WDR78 SYT2 MCCC2 B3GNT3 SCAMP5 BACE2 PSRC1 RNF216 DCLK1 ZNF480 KIAA0556 ING4 ESRP1 KCNJ14 RAPGEF5 IGLV6-57 ADAM12 FMO6P COL5A2 TPO SPTBN5 OS9 TYRO3 PTN KCNB1 TFCP2L1 TIAM2 C1orf56 RAB3D MMP24 FSCN2 PMS2P1 ME1 FKBP9 MAP3K9 RARRES1	up	*
GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP	0.0013178	0.0157488	0.4550599	0.3443386	1.568258	180	HELLS CDC45 BUB1B NEK2 UBE2T TTF2 SRGAP3 CDCA2 NIPSNAP1 POLE STIL ESPL1 CDC6 TPX2 MCM4 ARHGAP33 TYMS AP1G2 HOMER3 DPY19L1 AURKA LARS2 RAD54L LMNB1 CENPO RAD51AP1 DCTPP1 KHK HES6 SPC24 ZCRB1 KNSTRN HPS4 IQCB1 CENPH PACS1 TNNI2 SSX2IP SNCAIP DNMT1 SLC35C2 CENPQ ATAD5 NFXL1 PALB2 OLFML3 CENPT SH3BP5L NEDD8 STK35 GLIS3 PRIM1 TRIP6 PFKM ARHGAP11A OXCT1 LBX2 TNS3 CPT1C KIAA1522 PPIA GPN1 CCDC91 ZNF367 KIF24 APOBEC3B APEH SLC38A10 FURIN BCL7A FASTKD3 ZNF579 TMEM9 HSD17B7 MMP14 LRP8 MAP3K5 LOX	up	*
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN	0.0005774	0.0082877	0.4772708	-0.2963094	-1.568225	169	GPATCH11 PAN3-AS1 TUBD1 GLTPD2 EGR2 PRPF38A S1PR1 BCL2A1 PPM1D IL23A KLF10 ZNF410 MED19 NR4A1 LCMT2 ADO TACR2 EVI2A SH2D2A SLC25A32 MIR17HG GLB1 CREM CRNKL1 ARL5B ELP5 GPR183 KBTBD8 FAM177A1 EPC2 GIMAP1 BAZ2B NAB1 C16orf72 GPR18 ZNF267 FAM98B GEM EXOC2 MIR155HG TXNDC15 TEX10 FBXO30 USH2A ZNF165 NABP1 LPAR6 DNAJA2 PUS3 TMEM184C EGR1 ALG2 CHAC2 BCL10 ZNF347 TRMT10C TMEM165 FNIP1 NR4A3 IRF4	down	**
TTGCACT_MIR130A_MIR301_MIR130B	0.0000071	0.0002066	0.6105269	-0.2752481	-1.568139	342	WEE1 EREG SASH1 KLF13 PPARG DPYSL2 SIK1 CCDC88A DDX6 LONRF1 QKI AKAP7 GPCPD1 BMPR2 S1PR1 OTUD4 TGFBR2 ZEB2 ZBTB4 PTPRM HECW2 RAPGEF4 WNT2B MTF1 CAMTA1 PEX5L NDEL1 ATP6V1B2 LRP4 AGO4 NRARP NPNT PPP6R3 PRKD3 TPP1 SOCS5 SNIP1 ITPK1 M6PR EPS15 ELK3 N4BP1 PAFAH1B1 CALM2 NRBF2 NCOA1 BTG1 ADCY2 VPS37A PHACTR2 APPL1 HECA CPEB4 ZFP91 ATP11A SNX2 KBTBD8 NAA30 EPC2 ACSL1 AGFG1 PELI1 PTP4A1 HIVEP2 RUNX3 BTBD7 TIMP2 AP1G1 PHF3 TESK2 ZFYVE9 YTHDF2 SKIDA1 CNOT7 ATXN1 HBP1 ANKRD12 NPTN PLAA MBNL1 RXRA LDLRAD4 MIER1 WDR1 INO80 CEP170 RTN1 CHMP3 RAB5A UBE2D1 BRWD1 G3BP2 ULK2 NPAT CUL3 KIT RNF38 LDLR NRP2 NR3C2 RHOT1 ZFPM2 WDFY3 SPOPL MIER3 USP48 ZFYVE26 MAP4 STARD13 MB21D2 BHLHE41 CLIP1 ZNF800 LNPEP CLOCK CMPK1 FAM53B EFNB2 CD69 SPTY2D1 IER3IP1 WDR47	down	***
ENK_UV_RESPONSE_EPIDERMIS_UP	0.0004479	0.0067385	0.4984931	0.3315271	1.568136	253	PKP2 RUVBL1 GALNT6 PRSS2 FUT3 SLC2A1 HILPDA NPIPB3 POLE KRT16 ESPL1 CYP27B1 LSR TYMS SHMT2 XPOT TNC RUVBL2 PAFAH1B3 HOMER3 ITGB4 MDFI AIMP2 TGM1 ACTL6A PFKP XRCC1 EHF FDXR PHB FUT2 CMAS OSMR ULBP2 ATIC TNFRSF25 ACP6 SLC25A13 CDH3 CPNE1 KXD1 METTL3 DNAJC7 TPD52L2 NET1 DPP3 TUBG1 SPG7 PSMA5 COPS7B HDAC1 POLD1 ELAC2 CCT7 CDC20 LIPG BCL2L1 ENTPD3 STAMBP SURF2 CACNB3 RCC1 SLC1A5 STK39 PRMT5 ZNF212 ME1 SCO2 PRIM1 ANAPC2 HK2 PRSS22 SNX7 CARHSP1 STK25 PGAM1 XPC NMT1 HGS ADAM8 COPZ2 KRT17 DHRS9 DDB2 PLXNB1 PRKAG1 APEH USP20 SRM ADSL RWDD2B CES2 TMPRSS4 TUBGCP2 VLDLR	up	**
GSE3982_MAST_CELL_VS_TH2_DN	0.0019822	0.0212919	0.4317077	0.3455808	1.568100	176	RIBC2 TRIP13 FOXM1 GPT CDC45 GABRB3 TIMELESS PLK1 SFXN1 CDC25A MIS18A MYL6B COQ3 AURKA TPR RSRC1 MCM3 LMNB1 LIG1 ORC6 DCTPP1 INPP4B BLM SLC25A10 CKS1B APLP1 DDX51 BIRC5 GMNN GOLGA8A MRPS2 PDK1 SPAG5 FADD ETFB PA2G4 MRPL11 SSRP1 KIF20B IGHM POLD1 NUP85 DGKA RPA1 TDP1 URB1 ATAD2 CEP152 TCERG1 MSH2 GBP1 USP39 PPP6R2 PAXIP1 ETHE1 ADRM1	up	*
REACTOME_OPIOID_SIGNALLING	0.0053773	0.0451438	0.4070179	-0.3403361	-1.568045	74	ADCY9 ADCY4 PDE1B PRKAR1A PDE4C GNGT2 PPP3CA GNG7 PDE4D PPP3CC GNAI2 PDE1C PPP2CA ADCY2 CREB1 PRKACA CALM1 PRKCG PPP2CB GNAI1 GNG5 PPP3R1 GNB4 PDE4B	down	*
GO_CARDIOCYTE_DIFFERENTIATION	0.0016035	0.0181077	0.4550599	-0.3101789	-1.567983	122	SOX18 TBX3 BMP2 SIK1 FOLR1 SOX17 MEF2A TGFBR3 TBX2 LMNA WNT3A HNRNPU TCAP REST MIR24-2 ZMPSTE24 TBX5 MYH11 HES1 TGFB2 SRF RBPJ SLC8A1 NOTCH1 ADRA1A CACYBP TGFB1 MIR23A MYOCD GATA6 ACTN2 RGS2 RXRA PDLIM5 ARRB2 EDN1 NRG1 SMAD4 GREM1 MAPK1 MYH10 ITGB1 EFNB2 CALR	down	*
GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_UP	0.0036205	0.0337566	0.4317077	0.3562546	1.567828	133	SLC26A4 PTPRT ACY3 APOLD1 TRIM17 CHCHD6 CHST4 PIF1 NIPSNAP1 SEC14L5 KCNT1 XDH LRRC27 NLE1 MYBPC2 GPR182 ANKRD52 ASPHD1 WDR73 EEPD1 WDR31 TMEM231 TSPAN1 MYO19 RABL2A ACBD4 POMT2 CEP128 ENPP2 CLTB ABCC9 RABEPK CH25H ANK3 MED27 CNTN2 CAP2 TMEM141 INO80E MTIF3 PPP6R2 KIAA0825 F13A1 ALKBH6 PGPEP1 CELSR3 KRT80 FUT10 PARP2 GLIPR1L1 POLRMT DRG1 ITGB5 FAM110C	up	*
LU_EZH2_TARGETS_UP	0.0009687	0.0124226	0.4772708	0.3343509	1.567811	237	FGA BIK PPP1R1B RUVBL1 S100A2 PAGR1 THOC3 DDIT4 NUDCD3 PRIM2 PHGDH ZP3 AP1S1 TRIB3 MYL6B TRIM16L NUDT1 PODXL2 ODF2 IFT43 SNCG SNHG11 ZNHIT1 PSMD4 CBY1 KLHL35 PIH1D1 PRMT6 WASH2P ISOC2 BCAS4 WDR54 ADAP1 TCF20 KLHDC9 TRAPPC12 ARTN ETFB UNC45A TSPAN17 JOSD2 ZNF133 LONP1 ZMAT5 RAD51D CASP7 HDAC1 MGMT DLK2 AHNAK2 S100A13 ZNF814 RMND5B KLHDC3 FAM71E1 CENPV ZNF616 RPUSD1 WDR83 SURF2 LSM7 OGFR CBR1 HAGHL ELFN2 MIEN1 TMEM141 AMDHD2 ATOX1 ARL17B TRIP6 TYSND1 NDUFA8 MPG PPP1R14B ALKBH2 ZNF629 MFSD3 PDXP SIGIRR COMTD1 RPL36 LPCAT1 PSMB10 MEX3D RPLP0P6 PGAP3 PAQR7 PMVK TLCD1 RPS6KB2	up	*
GSE13522_WT_VS_IFNG_KO_SKIN_DN	0.0034047	0.0322630	0.4317077	-0.3313647	-1.567122	85	MGAT3 NOVA2 SOSTDC1 FBP1 PTPRE THBD FUT1 FBXO3 ACSM1 CBL RBM7 RAB33B NLK SLC25A37 ZYG11B PTPRO PEG3 ADAMTS9 NPAS3	down	*
GO_HISTONE_BINDING	0.0016496	0.0184984	0.4550599	0.3483231	1.567117	164	HJURP ZMYND8 L3MBTL1 UHRF1 MCM2 NCAPD2 SMARCC1 TP53BP1 TTLL12 CHAF1B YEATS2 BRD9 PIH1D1 PRMT6 IPO9 CKS1B NCAPG2 CBX5 ASF1B ING4 WDR5B NPM3 VPS72 TRIM24 SSRP1 ANP32E NOC2L LRWD1 PRMT7 CHD5 PARP9 BAZ2A SUPT16H L3MBTL2 PWWP2A UIMC1 PYGO2 RCC1 SMARCC2 ATAD2 SMARCA4 DTX3L MLLT6 BCAS3 TONSL SRCAP SBNO2 KDM5B NCAPD3 PWP1 SART3 MBTD1 SPHK2 RAG1 NPM1 CHD8 RNF8 MSH6 MLLT3 WDR5 CXXC1 USP49 MTF2 BRD4 KMT2D SAP30L	up	*
AAAGACA_MIR511	0.0006599	0.0092195	0.4772708	-0.3008613	-1.566517	161	ACE TXNL1 QKI ANAPC15 SEMA6D C1orf21 EMILIN2 PRELP NLK REV3L CAMTA1 AGO4 KCNMA1 ZCCHC24 KLF9 ZADH2 SOCS2 RECK MBD2 SLC6A6 ZNF706 CRIM1 EFR3A FOXN3 BTG1 CREBRF SCN4B CREM PSMA1 CELF1 MAP4K4 RHOJ ENPP4 KLHL18 ATL2 DEDD CDK14 PELI1 LMCD1 CALM1 VAV3 YTHDF2 MAP3K2 PCDH17 TOB1 SYT11 DCTN4 TRAPPC8 EPHA4 ZDHHC21 RHOT1 RAB2A ARHGEF17 DUSP6 KCNE1 FIP1L1 NR4A2 HAS2 ZNF654 CCNT2 ADAMTSL3	down	**
GO_LEUKOCYTE_CELL_CELL_ADHESION	0.0000446	0.0009853	0.5573322	-0.2813819	-1.566468	283	SIRPB1 PECAM1 ADTRP CD55 SPN IL1B FYN CD44 CAV1 PRKAR1A CDC42 TGFBR2 IL23A RHOA ANXA1 MIR146A CD5 ADA ITGA5 MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 TFRC ZMIZ1 IL10 NRARP DUSP3 PTAFR KLF4 ROCK1 CLECL1 SOCS5 FAM49B PTPRC SELL SELP JAM2 IGFBP2 SFTPD SMAD7 IL7R HES1 GNRH1 NCKAP1L CD80 IL6 CD160 ETS1 PDE5A RAC2 CCR7 PIK3R1 CD83 GRB2 MALT1 RC3H1 DOCK8 AP3B1 TBX21 TIGIT PELI1 RUNX3 CD74 CD1D ZBTB1 CD6 LRRC32 MIA3 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1 ICAM1 SELPLG IL18 RIPK2 NLRP3 HAVCR2 ADORA2A PAK2 KLRK1 TNFSF9 CD70 ZBTB16 CX3CR1 ICOS ITGAL ITGB1 S100A8 HAS2 NDFIP1 EFNB2 BCL10 HMGB1 CD3E IRF1 RC3H2 TNFRSF13C DUSP22 NR4A3 CD4 CASP3 NFKBIZ EBI3 CBFB PNP FERMT3 PYCARD	down	***
GSE17721_CTRL_VS_LPS_1H_BMDC_DN	0.0010150	0.0128472	0.4550599	-0.2996898	-1.566318	162	EREG OSBPL1A SOWAHC ZC3H12C F2RL3 DDX6 CITED2 MTMR10 IGSF6 IL23A IER2 CCNL1 MAP3K8 LUZP1 PTX3 NR4A1 NFE2L2 BTG3 TIPARP MEFV CDKN1A ATF3 AQP4 C9orf72 ID2 INHBA MAFF NRBF2 PROCR MTPN KIF13A OASL JUN PPP1R15A PTGER4 FOS SLC4A5 RIN2 CHORDC1 EPHA3 EHD1 DPM1 SBF2 TSC22D1 IRS2 CCR1 KIF17 CALB1 TAGLN CCR6 ICAM1 OSR1 PIP4K2A RIPK2 KCNJ9 B3GNT2 DNAJB9 NABP1 BHLHE41 CHIC2 CLEC4E FPR1 ZFP36 EFNB2 DNAJB4 SYCP3 TOR2A GABPB1 DLD NKD1 CLVS1 UFSP2 CFLAR EBI3 DUSP2	down	*
GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN	0.0003882	0.0060424	0.4984931	-0.2958839	-1.565912	172	RAB11FIP1 RTKN2 SC5D IL17RB SWAP70 SNX10 CLDND1 TBC1D2 NEDD9 TRIB1 RFTN1 HBEGF MAP3K8 RANBP9 TFRC MAP2K3 TNFSF12 UHRF1BP1L SOCS2 ERP44 IRAK2 SMAD7 GCA MBD2 STK24 PHTF2 SGK1 IL2RB HCST SH3BP5 DESI2 RAC2 LYRM1 OSM TNFRSF9 RALB TAGLN2 RUNX3 PKD2 MYL12A PEA15 KAT2B PDE4B LDLRAD4 CTTNBP2NL MIR155HG ELOVL1 SEC61B METTL7A COPS8 PDE4A DLST ETFDH CSF2RB CTSH ZBTB8OS	down	**
GSE39556_CD8A_DC_VS_NK_CELL_DN	0.0007500	0.0101570	0.4772708	-0.2949560	-1.565876	174	CXCL3 KMO CD55 SIK1 FIG4 FOLR1 S1PR1 CD22 TGFBR2 TMX4 DNASE1L3 ZEB2 KIAA0355 ATP2B1 SH2B3 TACC1 GRN MCL1 GPM6A ADARB1 MTMR6 PTPN21 BNIP2 PIP5K1B PTAFR TJP1 CXCL2 SMAD7 HCK BTG1 EMP3 RPS6KA2 MYO1C SERPINB8 APBB2 STX7 CRYM UVRAG DENND4A XYLT1 NIPA2 PDLIM1 AOX1 APLP2 SBSPON RGS2 GPR18 TNFAIP8 CCDC69 SPIB ESYT1 TBC1D1 SP100 METTL7A CD19 LYST CYTH1 RNF13 EVI5 SETX HERPUD1	down	*
GSE45365_WT_VS_IFNAR_KO_CD11B_DC_UP	0.0020411	0.0217818	0.4317077	0.3497453	1.565206	156	UNC5CL STYK1 THEM4 CABIN1 NIPSNAP1 MSTO1 EIF3B ACY1 LIME1 AARS2 ANO9 RPL39L LINC00954 KLHDC4 ANKEF1 SBK1 SMYD5 MTG1 ALG3 HPS4 PPIL2 DDX51 TNFRSF25 JAKMIP1 TCF20 CMTR1 GNPNAT1 PEG10 NOP2 ZNF827 FAM102A GIPC1 PELP1 YDJC TRMU LMF1 KRI1 NAT9 L3MBTL2 C12orf65 UTP20 NOSIP SURF2 WDR35 CLUH ANXA2P1 ANK3 GLO1 MAP3K14 MRPS25 TYSND1 SOX12	up	*
MODULE_121	0.0045701	0.0400068	0.4070179	-0.3326502	-1.565088	82	IL1A IL1B INSIG1 FOSL1 GAS6 CD8A ERG CD5 HBEGF KLF6 GRN ZEB1 PDGFA DAB2 EVI2A MAPRE2 BTG1 EMP3 CD8B AREG IL6 OSM RUNX3 CD86 CD81 IL18 BCAT1 EDN1 TNFSF9 CREG1	down	*
GO_INFLAMMATORY_RESPONSE	0.0000003	0.0000140	0.6749629	-0.2583779	-1.565066	562	FFAR4 CXCL3 GPR17 NLRC4 ACP5 IL17RB IL1A FOXF1 HMOX1 TEK OLR1 EDNRB PPARG WFDC1 IL1B FABP4 LIPA BMP2 CDH5 LPL CD44 LY86 CCL3L1 CCRL2 CALCRL MYD88 TBXA2R C5AR1 CASP12 IL1RL1 IL1RN SLC11A1 NFATC3 IL23A HSPG2 ACER3 DNASE1L3 PDE2A APOD CD36 ANXA1 MIR146A PLA2G7 ADA CLEC7A TNIP3 FOXP1 PTX3 GATA3 JAM3 SIRPA RB1 IL18R1 NFE2L2 GRN CASP5 SLC7A2 IL10 MAP2K3 PTGIR CCL22 BIRC2 MEFV CASP1 BST1 PTAFR KLF4 AOC3 THBS1 CEBPA SOCS5 LY96 CCL3 NFKB1 NR1D2 PTPRC CXCL2 IRAK2 SELP AXL CCL4 TLR4 PTGER3 XCL2 FCER1G PER1 CYP26B1 PTGIS HCK NRROS PRCP RBPJ IL17D CNTF IL6 PSEN1 SOCS3 SNAP23 APPL1 C1QA JUN PSMA1 NOTCH1 ETS1 HRH1 TYROBP TREM1 IFNGR1 PTGER4 CCR7 OSM PTGER2 REL SUCNR1 CXCL5 CST7 PXK NDST1 FOS SIGLEC1 BCL6B TREX1 PIK3AP1 SMPDL3B CCR4 CHIA TGFB1 CD6 FPR2 NLRP6 CD81 ORM2 CCR1 PLAA CCL20 SYT11 UNC13D CCR6 ICAM1 IL18 IL18RAP LAT CXCR4 RIPK2 NLRP3 HAVCR2 EPHA2 PLGRKT TLR10 NFKBIA ADORA2A KIT CTSC SCUBE1 AIM2 P2RX1 RORA THEMIS2 ITCH LDLR ANO6 LYZ SPHK1 MS4A2 CYBA SERPINE1 C5AR2 CNR2 C5 CLOCK ITGAL TREM2 ZYX S100A8 FPR1 NDFIP1 TBC1D23 NFAM1 PTGS1 PIK3CG SIGLEC10 BDKRB2 FPR3	down	***
GSE3203_WT_VS_IFNAR1_KO_INFLUENZA_INFECTED_LN_BCELL_DN	0.0032854	0.0312942	0.4317077	0.3507633	1.564816	151	TRNP1 NPAS1 PPP1R14D CABIN1 CA12 DPYS C6orf132 NEURL2 BPIFB1 FAM171A2 MAD1L1 HEBP2 MARK1 CXCL11 GPX8 CBX5 GOT2 AP5Z1 COA4 RNF207 SEMA4F ITGA2B EFTUD2 MZT2B MLF2 NGFR MRPL11 SALL4 TK1 SPTBN2 USP43 FHL2 IQCH NAGS ZNF428 ZNF558 CCSER1 LRIG1 OVOL2 LSM4 NEFH EIF3K CAPN10 R3HDM4 FOXD2 BCL6 POLR1A COPZ2 NUP210 RABL6 PPP1R14B MOK SLC1A7 NELL2 KCNK6 RPUSD3 GLIPR1L1 PAQR8 PRSS50 HRAS	up	*
KONDO_PROSTATE_CANCER_WITH_H3K27ME3	0.0057539	0.0474211	0.4070179	-0.3405818	-1.564706	75	CLEC1B PHACTR1 GPR15 CLDND1 ELMO1 MARCO ERG SIGLEC6 ENTPD1 TNIP3 TFEC RUNX1T1 CLECL1 C1QTNF7 AQP4 KIRREL3 TECTA TMPRSS11A CRNKL1 TMTC1 TREM1 EPB42 CD1D FPR2 CD86 SLC8A3 ACADL	down	*
GSE32423_CTRL_VS_IL7_IL4_MEMORY_CD8_TCELL_UP	0.0002793	0.0045945	0.4984931	-0.2965379	-1.564590	171	GPR17 HVCN1 PTP4A2 ARRDC4 COQ2 ELF2 SFR1 MTMR10 MOB1B RBM7 CACNA2D2 ARSB SWT1 RAB33B ZDHHC2 RANBP9 CRTAM AHNAK HNRNPA3 STK17B ABCC4 UBQLN1 TMBIM1 LRRC40 ZBTB43 ARL4A MATN2 UBASH3B BACE1 CDKN2AIP SRF BTG1 MYLIP YBX1 RHOBTB2 MAP4K4 THUMPD1 CD7 NAA30 CDK17 FAM204A C19orf38 ZBTB1 TSC22D1 TOB1 LTBP1 DISP2 SRSF10 SDAD1 MAP3K4 KLRK1 THRAP3 GPR171 DUT PIEZO1 HNRNPH1	down	**
MIR548AA_MIR548AP_3P_MIR548T_3P	0.0000011	0.0000415	0.6435518	-0.2642503	-1.564250	460	SEMA6A SASH1 SWAP70 OSBPL11 TBX3 ZC3H12C RUNDC3B TRPC3 ZBTB34 TMEM170B OTUD1 PPP4R1 CCDC88A DDX6 CITED2 CALCRL ZCCHC2 ARL8B NR3C1 VAPA AGTPBP1 EPB41L3 MOB1B HEG1 ZEB2 DNAJB14 NUMB WWC2 BMP1 UBL3 PCYOX1 LMNA C1orf21 RAB33B SERP2 ZBTB21 RNF182 DACH1 MYCT1 TIPARP TAPT1 PER3 FOXO1 HNRNPA3 FAM124B RNFT1 PRKD3 KLF11 ZFAND5 VASP FBXL3 KIF26A SSH1 CDS2 PAPSS1 TEF CCND2 ARAP3 ZBTB43 WASF3 MPC1 ZNF706 PIAS1 FOXN3 RPS6KA2 MOB4 SENP3 C2CD2 MITF GABPA DDX17 C11orf58 CYCS RABGAP1 FOXN2 AK1 WTAP MCM9 SNX2 SKIL GLIPR1 TTC14 SP3 PABPC4 DDX5 MBNL2 CREB1 COBLL1 PREX2 YWHAZ SNRK CDK14 PELI1 CDK17 MAPK8 ING3 DDHD2 TMX3 CNOT7 MAP3K2 PIM1 PPP3R1 CCR1 MACF1 KAT2B MBNL1 JUND NEK1 NBN EPN2 BRWD1 ZDHHC21 CREBBP RBMS3 TBCEL LIMCH1 RET TTC28 TIMP3 RNF38 SCAI TMEM87A PRKG1 KIF1B RORA	down	***
GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP	0.0017086	0.0189609	0.4550599	0.3467432	1.563860	169	DDX11 GPT ZMYND8 KIF18B DEPDC1B COL7A1 PLK1 KNOP1 RAD54B KCNMB4 TNC NOS1AP RPAP1 COPG2 CENPL VANGL1 NEB CENPO RAD51AP1 ANKRD16 CXCL9 CCDC136 STXBP4 ZNF512B ANAPC5 FAT1 PICK1 TNK2 STAT2 DPH7 SF3B3 IGSF3 HMGXB3 ZNF692 TBX1 ARFRP1 BCL2L12 KDM3B NRF1 BAZ2A RNF187 STRN4 CKAP5 CENPM FITM2 SRRT TIAM2 CHTF8 KIF21B RNF215	up	*
SENESE_HDAC1_AND_HDAC2_TARGETS_UP	0.0002327	0.0039065	0.5188481	-0.2897145	-1.563853	201	CXCL3 EREG IL1A CD55 ROBO4 TIE1 LPXN BMP2 LDB2 FOSL1 BCL2A1 TGFBR2 DNAJB14 SH2B3 SPIRE1 PTX3 CAMTA1 JAM3 SFRP1 CES1 SRGN PDE4D TFRC MCL1 MYCT1 SLC7A2 KDSR PTPN12 PLAUR LAPTM5 IRAK2 CCND2 PLEKHB2 ELK3 IL7R UBASH3B NUS1 MAFF IL24 AFF3 TMOD1 CREM PHTF2 SNAP23 CPEB4 RAC2 PCGF5 PSTPIP2 CXCL5 TNFRSF10B GFPT2 GPR3 PPTC7 KYNU GNA13 RGS2 SNHG16 CCL20 GEM CEP170	down	**
GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_UP	0.0017268	0.0191044	0.4550599	0.3456572	1.563822	173	BDH1 BUB1B POLE ASPM DGCR8 CCT6A RCCD1 MRPS35 FAM220A AP4M1 GTPBP3 WIPI2 PRKDC RAD54L TOPBP1 CHEK1 TIMM50 RAD18 IPO9 SLC28A2 PHB IDH2 STXBP4 GCKR ZNF32 KIAA0753 ANKRD54 ACP6 MECR KXD1 RNASEH2A SNRNP25 MZT2B GNPAT FANCF AARSD1 LRRC8D LMF1 METTL22 PKP4 CCDC51 SASS6 PRODH DNAJC21 POLR2I SLC1A5 RRP36 TCHP CBR1 BANF1 SNRPD2 CSNK1G2 WDR77 HOOK2 SNX7 MLLT1 ATG2A SMC2 MAPK8IP3 SWI5 SMPD4 DNAJC10 ZMAT2 PGPEP1 FRMD6 TRUB1 SLC35G1 RRS1 CALU BCKDK RCN2 LUC7L3	up	*
MIR6507_5P	0.0000826	0.0016442	0.5384341	-0.2805727	-1.563732	268	ZNF366 SGK3 CD55 QKI BMPR2 IDI1 OTUD4 STARD4 DNAJC3 PTPRM SLC36A4 ABCG2 CSGALNACT2 PPP2R2A SLAIN2 HIPK4 MYCT1 RHOB ROCK2 ITPRIP PTPRO LIN7C TSPAN12 KLF9 ROCK1 ZFAND5 DRAM1 ZADH2 GAPVD1 DOCK9 PDE3B NR1D2 GPR85 PAPSS1 ID2 CLK4 KIAA0408 PRDM5 SPRYD7 AKIRIN1 NCOA1 LACC1 CDC40 KIF13A NEK7 APPL1 PODN CNTN3 ARL5B ADRA1A PDE5A OSBPL9 C11orf58 APBB2 PCGF5 TUBGCP3 GRIK1 MEAF6 PPM1F ACSL1 MOB1A HIVEP2 MSMO1 ZBTB1 CCP110 MAP3K2 ORC2 ACYP2 MICU3 PGGT1B ARPP19 FGF2 EPB41L5 CDC42EP3 VPS4B ARIH1 USH2A ZDHHC21 ULK2 METTL7A CEPT1 SCAI PAK2 FOXJ2 PTEN FAM126B PRKG1 CAMSAP2	down	**
DCA_UP.V1_UP	0.0056406	0.0467883	0.4070179	0.3624785	1.563628	118	NPC1L1 PTPRT CDC45 GRIN2D IGKV3D-15 EYA2 COLQ CABIN1 CATSPERB AURKB SIX1 ZNF117 CLCN2 AOC1 KREMEN2 TNNT2 CASP2 MDK KLHL3 GABRB2 MCTP2 BCAS4 GIPR ALG1L2 GDPD3 FMO6P LRFN3 ZSWIM1 NTN3 TYRO3 RAI1 TTLL3 TNS4 NRXN2 ANKRD1 CUBN INSL3 ZNF91 ADARB2 COPZ2 MIR600HG LPAR3 SARDH DNAL4 INO80B OVGP1	up	*
GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP	0.0004010	0.0061821	0.4984931	-0.2954131	-1.563421	172	ACVRL1 OLR1 HVCN1 WFDC1 MYD88 CLEC10A PRPF38A FGR RBM7 ARHGAP10 SSTR1 TTL CLEC7A KLF10 ANPEP NFE2L2 EPB41L2 ATP10A RHOB PTGIR DUSP3 MEFV BNIP2 CDKN1A RBMS1 ITGAX RRP8 SS18L2 DUSP1 INHBA BCLAF1 KCNA5 TMEM9B SLC25A25 APBB2 CD151 SLC3A2 ATG3 KLRC2 TIMP2 UBXN2A CBFA2T3 GNA13 KTI12 GEM ICAM1 MOB3B	down	**
GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP	0.0005075	0.0074426	0.4772708	-0.2938675	-1.562956	184	EGR2 BCL2A1 CD9 HPS5 ATP2B1 LTBP4 ADAM17 GLS EIF4E IL18R1 NFE2L2 NDEL1 ZFYVE16 SRGN CD58 EVI2B MAP2K3 ACSL3 PRKD3 VASP SPAG9 PER2 NFKB1 ATF3 CDS2 VIM CCL4 MATK CALM2 MAPRE2 PPP2CA NSMAF PNO1 CD48 GABPA CYCS RHOG TMEM251 IPO7 SP3 IDS HOMER1 NOL7 HIVEP2 PEA15 DUSP5 GNAI1 ATP6V1A PDCD1 GNG5 UTP3 PHLPP2 CCL20 AMD1 WDR1 CEP170 UBE2D1 TRAF1 COPS8	down	**
GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_DN	0.0005323	0.0077412	0.4772708	-0.2949584	-1.562681	173	EPAS1 ST8SIA6 GPR65 HSD17B11 KLHL8 ST3GAL6 CLYBL NEDD4L TBXA2R DNAJB14 TXNIP ZBTB4 CLCF1 BMP1 BTG2 SERINC1 ACOT2 FOXP1 KLF6 PRSS12 PAG1 LAIR1 CYP4V2 PPM1K TCP11L2 PDE8A MGAT4A MARVELD1 ID2 IL7R PIK3R5 SGK1 RNF141 NDNF RHOBTB2 CCR7 GLIPR1 DDX5 LETM2 KLF2 MBP FOXO3	down	**
GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP	0.0012559	0.0151359	0.4550599	0.3457213	1.562657	170	FOXM1 POM121L9P CDC45 FANCI CHEK2 BUB1B NEK2 FAM153B PRIM2 BRCA1 IRS1 TTK SLC27A2 KIF14 SPP1 STIL ESPL1 COCH CCNF MELK RPL39L DPY19L2P2 WASF1 BUB1 FANCA DPY19L1 RRM2 CDC25C RAD51AP1 BLM RGS4 MGLL CDKN2C DNA2 SPAG5 RAPGEF5 NRGN CCNE1 DLGAP5 AGL TRIM9 ANP32E KIF20B SPA17 POLD1 GNAZ CDC7 TADA3 RDH16	up	*
chr6p21	0.0018919	0.0204975	0.4550599	0.3469246	1.562571	159	UNC5CL KCNK5 SPDEF IP6K3 SLC26A8 SAYSD1 XPO5 GUCA1B SRPK1 AARS2 C6orf132 DNPH1 CUL9 CUL7 MDFI BRPF3 PEX6 DNAH8 ARMC12 ADCY10P1 NFYA C6orf223 DDR1 PPIL1 TTBK1 MEA1 ETV7 CMTR1 PACSIN1 POLR1C OARD1 TCTE1 UQCC2 ITPR3 TAPBP YIPF3 MAPK13 TSPO2 ANKRD18EP TJAP1 DLK2 SYNGAP1 ABCC10 KLC4 KLHDC3 MDGA1 HMGA1 ZNF76 RPL7L1 LRRC73 ZBTB9 RRP36 GLO1 MRPL14 APOBEC2 STK38 TRERF1 CCDC167 GTPBP2 UHRF1BP1 TMEM63B SUPT3H ENPP5 LEMD2 SNRPC PPP2R5D	up	*
GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_UP	0.0023204	0.0239832	0.4317077	0.3472116	1.562515	162	TRIP13 MCM10 IGF2BP3 MPP6 CPSF6 DEPDC1 RACGAP1 E2F8 GMPS AP1S1 CDC6 CCNB2 FIGNL1 KNOP1 MCM4 DTL EXO1 KIF23 DPY19L1 SAE1 ATR RRM2 AKAP1 KLHDC4 MCM3 CDC25C CCDC58 BRI3BP THYN1 MAD2L1 AHCY TIMM50 SPC24 BRIP1 CENPH BIRC5 CENPP PA2G4 TACC3 SNRPA ARL6IP4 GALNT3 ATAD5 COX10 CDC7 PPP1R8 UTP20 SNRPD1 LTV1 SLC35A3 PRMT5 BANF1 RAD51 COX5B WDR76 PGAM1 CLNK DDX52 ZBTB32	up	*
GSE40068_CXCR5POS_BCL6POS_TFH_VS_CXCR5NEG_BCL6NEG_CD4_TCELL_UP	0.0005840	0.0083622	0.4772708	-0.2941241	-1.562361	179	SGK3 USP12 CTDSP1 TBXA2R S1PR1 NR3C1 DENND2C RFTN1 TXNIP ZBTB4 CNST CLCF1 GM2A FOXP1 PAG1 EPM2AIP1 MCL1 TIPARP CDADC1 FOXO1 TCP11L2 KLF7 NR1D2 SELL CD302 PNRC1 SHE IL7R ADD1 MCMBP SNHG8 RPL9 WTAP ELOVL7 CCR7 ATXN1L SKIL ENPP4 RC3H1 CEBPZ LETM2 FOXO3 ICAM2 ZRANB1 PHF2 CLCN6 PDE4B	down	**
GSE24726_WT_VS_E2_2_KO_PDC_DN	0.0005154	0.0075371	0.4772708	-0.2934677	-1.561878	177	SLC31A2 ACP5 PECAM1 HVCN1 EGR2 HCAR2 GTF2E2 AKAP7 SLC11A1 DNAJC3 ADAM17 CYB5A EMILIN2 LITAF PAG1 CLN5 TOR1AIP1 NFE2L2 TIMM10B BNIP2 DRAM1 KLF7 MGAT4A PLEK RAP1GDS1 UBASH3B PIK3R5 FKBP15 HLA-DQA1 MMP19 ST6GALNAC6 METAP1 RNF149 VPS37A PKNOX1 CNNM2 JAK1 SDHD FAM177A1 TAGLN2 TRAPPC10 TESK2 NFYC STK40 ME2 FAM98B RLF CEBPD TXNDC11 ZDHHC21 TRAF1 ISCU PLGRKT SAMSN1 NRP2 ARRDC2 CYBA EGR1 ING1 AOAH	down	**
DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP	0.0000400	0.0009014	0.5573322	-0.2827955	-1.561377	260	WEE1 SECISBP2L CD55 ATXN3 SAMHD1 BACH1 DYRK1A OTUD4 RCHY1 PDCL ZEB2 ANXA1 KLF6 EIF4E FOXJ3 CRK CLK1 BTG3 PDE4D MCL1 TIPARP KPNA5 TBC1D9 DUSP3 STK17B STX3 ZNF24 NR1D2 CXCL2 ATF3 CAPZA2 DUSP1 GNAQ N4BP1 SMNDC1 RSRC2 TDRD7 ZNF330 MOB4 ID4 RYBP CREM COPS2 DCTN6 PNO1 NEK7 OASL NECAP1 JUN CELF1 SHOC2 DUSP8 RCAN1 PPP1R15A WTAP IFRD1 THUMPD1 SNRK AGFG1 SLC3A2 CDK17 LSM6 CCP110 BAZ2B GNAI1 GABARAPL1 GNA13 ARPP19 GEM FGF2 RLF RAB5A UBE2D1 SP100 POLR2M NUP98 OSER1 NFKBIA DNAJB9 ITCH TLK1 PMAIP1 YTHDC1 KAT5	down	***
GO_CELL_CYCLE_PROCESS	0.0000000	0.0000001	0.8012156	0.3047964	1.561274	1131	HMGA2 CCNO PKHD1 TRIP13 DDX11 FOXM1 CEP72 SPICE1 BRINP1 KIF20A MDM1 DDX12P STAG3L2 CDC45 TICRR MCM10 CHEK2 BUB1B NEK2 CCNB1 SOX2 CENPF TIMELESS PAGR1 STOX1 MND1 KIF18B NDC80 PRIM2 TBRG4 BRCA1 PHGDH TTK GINS1 CDK4 SMPD3 RACGAP1 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN POLE CNTD2 ASPM NABP2 STIL MSTO1 CEP70 PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 TFDP2 CCNB2 FIGNL1 RBBP8 MCM4 PRKCA CYP27B1 MCM2 RAD54B TYMS CDC25A MYBL2 PRC1 XRCC2 ORC1 NOX5 CCNF DTL TDRKH MCM8 MAP2K6 ZFYVE19 NCAPD2 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 WDR62 CASP2 MELK HMMR BTRC SMARCD3 DLG1 KIF23 CEP55 STAG3 MKI67 CUL9 BOD1 CUL7 FBXO43 KNTC1 RHNO1 KIF3B BUB1 FANCA MSX2 AUNIP TOP2A MAP10 GPER1 AURKA EME1 CBX3 REC8 ODF2 POLA2 SYCP2 POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 MSX1 CENPW POC1A CLSPN CXCR5 IL12B RRM2 CDCA5 PRKDC FSD1 NSUN2 RAD54L TOM1L1 KIF11 FANCD2 GPSM2 MCM3 HORMAD1 CDC25C SOX4 EGFR LIG1 EME2 TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 MDM2 AKT2 DSCC1 MGA PKMYT1 BRIP1 FBXL8 BLM PML C2CD3 CNOT3 ERCC2 MNAT1 STXBP4 SPRY1 SLC39A5 SKP2 RECQL5 PSRC1 INCENP KNSTRN CKS1B CDKN2C NUSAP1 CBX5 ANAPC5 ING4 CTDSP2 CDK1 CROCC POLE2 CEP97 CENPJ RFWD3 BIRC5 KIAA0753 GMNN SUN1 DIS3L2 E2F1 NCAPG PSMB5 CCNJL DNA2 KIF2A ANAPC7 FEN1 SSX2IP EZH2 CNOT11 SPAG5 EGF RAB11FIP4 SAPCD2 TRAPPC12 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP STK11 IRF6 KPNB1 GIPC1 MYO19 ANKK1 CEP63 CCNE1 CEP192 RHOC CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 MTOR NINL TACC3 RAD9A LLGL2 PSME2 KIF22 HIRA RAD51D MTA3 TRIM37 MYBBP1A CENPQ AKAP8L ESCO2 GAS2 FZR1 PKP4 NUDT16 CGREF1 KIF20B LAMTOR2 SGSM3 ANAPC1 SND1 CDK13 POLD1 PSMD2 JTB ATAD5 PPME1 SLX4 CDC7 RAD50 ANKRD31 CENPK SASS6 KLHDC3 SH2B1 STAG3L4 CENPV MEI1 CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B ROPN1B TUBG2 AAAS EFHC1 ALKBH4 BCL2L1 RPA1 CHMP4C WNT10B FANCM CDK5RAP2 MCM6 CHTF8	up	***
MIR12129	0.0017230	0.0190707	0.4550599	-0.3101996	-1.561164	121	KCNA2 BDNF UBR3 ARSB RAP1A CYYR1 NR4A1 TIPARP AMOTL1 SDCBP KLF9 SEC24B MGAT4A DOCK9 RBMS1 CXXC4 CCSER2 RNF139 PPP2R5C HSDL2 FAM102B LIN54 BTG1 KCTD12 SKIL PIK3R1 FAM43A YPEL2 EPHA3 KHDRBS1 MAP3K2 PCDH17 MIER1 SEC63 NUP98 ZDHHC21 SSH2 SIN3A RHOT1 MIER3 KALRN KCNJ6 ICOS RAB37 SLC38A2 KIAA2026 KMT2E CCNT2 KLHDC1 NKTR SIRT1 FNIP1 JARID2 KBTBD2 SETBP1 NSMCE4A PHIP	down	*
MIR655_3P	0.0000078	0.0002255	0.5933255	-0.2724257	-1.560997	350	WEE1 C18orf32 SLC16A4 TMOD3 SRSF7 HMGCR ACER3 HEG1 CLCF1 MCTP1 PCYOX1 ABCG2 CYYR1 PBX3 ZNF503 FZD4 HIPK3 GPBP1L1 DACH1 ZEB1 TCF7L2 EPB41L2 EIF1B CDADC1 TLE4 SRSF5 ZCCHC24 FMO2 ZFAND5 SOCS2 FBXL3 SYCP2L CLIC4 DOCK9 UBE2E2 GPR85 TADA2B PNRC1 FRMD4A CAPZA2 FAM76B ADD1 EFR3A CNOT6L NCOA1 SIAH1 C2orf69 SRF KANK1 MOB4 CREBRF WASF2 PHTF2 DCTN6 MAGI2 MITF SNX29 C11orf58 MAP4K4 RABGAP1 CSTA FERMT2 ATXN1L MBNL2 ATL2 FSD1L ATP13A3 CGGBP1 GAS2L3 AGFG1 CDK17 PTP4A1 CCDC85A TRAPPC10 ZNF521 TMX3 STRN ABHD13 NAB1 LRRC32 C8orf37 EXOC1 TOB1 MACF1 ADAM10 ARPP19 INO80D RBL2 MOB3B RTN1 FBXO30 TOB2 IPO5 FNBP4 ING2 GTF2F2 SCAI RORA FAM13C NRG1 RNF13 RAB2A KLC1 MAP4 UBAP1 KALRN EGR1 UBXN8 CHIC2 UBA6 SSB ITGB1 CCNK PIGK CTDSPL2 EBF1	down	***
GO_TRANSLATIONAL_ELONGATION	0.0033298	0.0316586	0.4317077	0.3608587	1.560615	120	TSFM MRPL46 DIO2 MRPS35 MRPL15 ERAL1 MRPL3 MRPL27 MRPS11 EEFSEC MRPS30 MRPL36 MRPL37 MRPS2 MRPL17 DPH7 MRPS12 MRPS34 MRPL11 MRPL52 DPH2 MRPL4 DAP3 CHCHD1 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 MRPL53 MRPL51 DPH5 MRPL14 MRPS25 MRPL55 GTPBP2 GADD45GIP1 MRPL9 SRP9 MRPL21 AURKAIP1 MRPS27 MRPL20 MRPL48 MRPS26 MRPS16 MRPL12 ZNF598 MRPL43 MRPL2 MRPS6 ABTB1 EEF1D MRPS7 EEF2K MRPL35 MRPL13 MRPL33	up	*
GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_UP	0.0020562	0.0219072	0.4317077	0.3486641	1.560386	155	PRIM2 DGCR8 RAD54B ZWINT TAMM41 GOLPH3L CASP2 TMEM41A TOP2A COASY ANKRD52 FAM162A SMYD5 IPO9 ALG3 SKP2 RNF216 CBX5 ASF1B POLE2 EZH2 MECR SF3B3 LIPT2 SNRPE HSPA4L MYO19 DNMT1 FANCG TELO2 THNSL1 DCAKD DPH2 AGPAT5 C12orf73 TADA3 PSMB3 MED24 TDP1 NDUFS7 RFC5 ICK WDR77 LPGAT1 MCU TARBP1 SMC2 POLR1B NMT1 RASGEF1A BCKDK PDXP MUS81 DHDDS APRT APBA3 NFE2L1 NPM1 TLCD1 ARFIP2 TRIM59 NDUFB2 TXN2 MTHFD2 POLD3 NUDT19 WDR12 SDHC KHSRP EIF4EBP1 GRWD1 AMPD2 NUP43	up	*
GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	0.0003620	0.0057222	0.4984931	-0.2933773	-1.560036	176	ARHGAP31 PECAM1 BDNF INPP5K QKI CRY2 AKAP7 AGPAT4 ZBTB2 RCHY1 PDE2A CD36 CD33 CSGALNACT2 STOM LAIR1 HNRNPDL SRGN AGO4 TBC1D9 LRRC57 KLF7 ZBTB43 CPT1A FAM76B RSRC2 SERTAD2 SRSF3 HERC1 ZCCHC9 SLC3A2 NOP10 FAM204A TFEB CHRAC1 SMCR8 MIA3 NFYC BRI3 WBP2 ATAD2B GTF2B GEM PCM1 PIP4K2A GPD1L JMJD1C KIT FOXJ2 THRAP3 MCOLN2 TMCC3 ITCH PUM1 SMAD4 NIPSNAP3A MED31 AFTPH SETX HIPK1 ANKS1A DNAJB1 MAP4K2 MTSS1 RCSD1	down	**
MORF_EI24	0.0026522	0.0264228	0.4317077	0.3626203	1.559929	114	TRIP13 CCNB1 XPOT ZWINT RUVBL2 SDHA BUB1 CCT5 NDUFS2 PRKDC ACTL6A ALG3 COQ9 TMEM106C SSBP1 CCT3 GOT2 LARP1 KXD1 VBP1 SNRPA SSRP1 MLEC TCEA1 DNAJC11 TM9SF4 SRSF1 HAX1 POLR2I SLC1A5 LSM4 ALG8 NUP62 NDUFV1 AP2S1 GLO1 DOCK3 VDAC1 SNRNP200 TMED9 VDAC3 EIF4G1 SART3 LYPLA1 AKR7A2 DGUOK FAM120A CS SEC24C HNRNPAB CALM3 PPM1G KHSRP BUB3 ATXN10 RAC1 RFC4	up	*
GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP	0.0006732	0.0093692	0.4772708	-0.2947296	-1.559864	169	SOSTDC1 GLIPR2 F2RL3 SNX10 CD9 TMX4 PDE2A RBM7 PTS RAPGEF4 LATS2 GM2A RAB33B ADRB2 FBXO8 FLI1 EVI2B ARRB1 AHNAK PPM1K ATL3 COTL1 CAPZA2 KLRD1 HLA-DQA1 CRIM1 C16orf54 EMP3 NSMAF EBAG9 SOCS3 PLEKHA3 LIMD1 PDE5A FOXN2 GMFG GPR183 GRASP RTN4R LPCAT2 TBX21 PELI1 PNPLA2 NKG7 IRF5 GPR18 SERINC3 SELPLG SESN1 C3orf38 RIPK2 GPD1L SCPEP1 TTC32	down	**
MIR374C_5P	0.0000055	0.0001690	0.6105269	-0.2724933	-1.559851	349	WEE1 C18orf32 SLC16A4 TMOD3 SRSF7 HMGCR ACER3 HEG1 CLCF1 MCTP1 PCYOX1 ABCG2 CYYR1 PBX3 ZNF503 FZD4 HIPK3 GPBP1L1 DACH1 ZEB1 TCF7L2 EPB41L2 EIF1B CDADC1 TLE4 SRSF5 ZCCHC24 FMO2 ZFAND5 SOCS2 FBXL3 SYCP2L CLIC4 DOCK9 UBE2E2 GPR85 TADA2B PNRC1 FRMD4A CAPZA2 FAM76B ADD1 EFR3A CNOT6L NCOA1 SIAH1 C2orf69 SRF KANK1 MOB4 CREBRF WASF2 PHTF2 DCTN6 MAGI2 MITF SNX29 C11orf58 RABGAP1 CSTA FERMT2 ATXN1L MBNL2 ATL2 FSD1L ATP13A3 CGGBP1 GAS2L3 AGFG1 CDK17 PTP4A1 CCDC85A TRAPPC10 ZNF521 TMX3 STRN ABHD13 NAB1 LRRC32 C8orf37 EXOC1 TOB1 MACF1 ADAM10 ARPP19 INO80D RBL2 MOB3B PDLIM5 RTN1 FBXO30 TOB2 IPO5 FNBP4 ING2 GTF2F2 SCAI RORA FAM13C NRG1 RNF13 RAB2A KLC1 MAP4 UBAP1 KALRN EGR1 UBXN8 CHIC2 UBA6 SSB ITGB1 CCNK PIGK CTDSPL2 EBF1	down	***
PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP	0.0038947	0.0355427	0.4317077	0.3602149	1.559702	119	CEACAM1 PCSK6 FOXM1 SLC26A4 BUB1B CCNB1 CENPF NDC80 TFF3 TTK GINS1 PLK1 AURKB PTTG1 CCNB2 MYBL2 CETP SMAGP BUB1 TOP2A KIF2C KIF11 LMNB1 RBP1 SPRY1 DCLK1 CKS1B CDK1 PEG10 SPAG5 RAPGEF5 TBX1	up	*
MIR582_3P	0.0061069	0.0496595	0.4070179	-0.3394158	-1.559349	75	GCOM1 U2AF1 LONRF1 RHOA SLC44A2 HERC3 ACTR3 ZBTB43 N4BP2L1 RAP1GDS1 PEAK1 HTRA4 NRBF2 NEK7 PPA2 MAP4K4 FERMT2 SKIL PALMD AZIN1 UBXN2A AKIRIN2 ATAD2B SCN7A DIXDC1 POLR2M	down	*
LAIHO_COLORECTAL_CANCER_SERRATED_UP	0.0036003	0.0336069	0.4317077	-0.3131621	-1.559347	106	SC5D DPYSL2 CAV1 ARL8B PRKAR1A VAPA ATP2B1 SPG21 ANXA5 SDCBP PLEKHB2 ELK3 EMP3 RBM34 RASSF2 TAGLN2 SNRK NDUFV2 PELI1 NOP10 RIN2 EMC7 TCF4 NPTN MACF1 ADAM10 ARPP19 BNIP3L PDLIM5 ARPC2 HSPA8 HNRNPC IQGAP1 EMC3 SVIL ATP1B1 HLA-DRB1 NXN CAPZA1	down	*
GO_REGENERATION	0.0008996	0.0117005	0.4772708	-0.3019277	-1.559134	152	TNR HMOX1 PPARG FOLR1 C5AR1 FGF10 TGFBR3 CD9 GAS6 TGFBR2 SCARF1 APOD ANXA1 MYOZ1 RAP1A LCP1 PPP3CA JAM3 NDEL1 GRN SGCA PTPN12 IL10 SRSF5 KLF4 CDKN1A AXL MATN2 ANXA3 AKIRIN1 KREMEN1 STK24 MTPN NINJ1 CNTF LAMB2 JUN NOTCH1 IFRD1 RTN4R	down	*
GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNAR_KO_UP	0.0006782	0.0094185	0.4772708	-0.2922891	-1.558949	183	EPAS1 SLPI ACP5 KMO RAMP3 ACVRL1 LIPA LY86 GTF2I CLEC10A MSRA TGFBR3 TGFBR2 DNASE1L3 ARHGAP29 ARSB RAPGEF4 ANXA5 RGCC CRTAM SCP2 MPEG1 OSTF1 ZADH2 PDE3B ID2 PRF1 FCER1G ALOX5AP KLRD1 PPP2R5A HLA-DQA1 TANC1 SNN TMEM9B PKNOX1 SGK1 SNHG8 TYROBP ELOVL7 CCR7 GMFG GPR183 RASSF2 WDFY4 RUNX3 ICAM2 C19orf38 TEC TSPAN14 ANKRD13A FCGRT GPR18 PDE4B PITPNA SPIB SETD4 TDRP COMMD8 DUSP7 LYST THEMIS2 EHD3 FEZ2 SUGT1 SPSB1 CTSH	down	**
GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_UP	0.0019815	0.0212919	0.4317077	0.3459567	1.558211	159	KLC3 LAD1 CHEK2 BUB1B TRIM17 NOVA1 PLEKHH1 TBRG4 GMPS BCAS1 EFNA5 KCNJ8 XPO5 TMEM81 DZANK1 HAUS5 TSGA10 TPBG CCDC77 GPSM2 PDZK1IP1 ASS1 PES1 PSRC1 KNSTRN PLOD2 AP5Z1 TRAPPC12 FOCAD LZTR1 ZNF354A SCLY PKP3 OSBPL3 FBXO4 COG4 SEC14L2 ABCC3 NOC4L USP21 FARSA ZNF622 CCNA2 CDH1 DTNB VPS33B ANK2 TNKS1BP1 ARHGAP5 MROH1 RHOT2 TBC1D32 ARHGEF39 POLR1B ZSCAN29 C1orf159 GGCX KHNYN ZFPM1 TIPRL LASP1 ZKSCAN4 MECOM DUS3L LZTS2 RNF40 ARMC6 IGDCC4 NDRG1 CNTNAP2 TMEM181 WDR25 FIBP IPO4 SLCO4C1 TTC3	up	*
GO_REGULATION_OF_CELL_SHAPE	0.0017338	0.0191657	0.4550599	-0.3078483	-1.558136	138	DLC1 FGD5 P2RY1 RDX FYN BAIAP2 CDC42EP2 CDC42 EPB41L3 FGR RHOA ANXA1 PLXNA2 PLXNA4 CRK ATP10A RHOB PARVB FMNL3 CCL3 WASF3 ZMPSTE24 HEXB HCK FMNL2 RHOBTB2 LIMD1 RAC2 RHOG RHOJ PALM FERMT2 PALMD RHOQ EPB42 GNA13 ICAM1 WDR1 SEMA4A CDC42EP3 ARHGAP18 BRWD1 RND1 PARVA KIT	down	*
PEA3_Q6	0.0000845	0.0016742	0.5384341	-0.2846833	-1.558059	230	GPD1 FFAR4 TSPAN4 HHEX LPXN BDNF CTSW RTN3 NCF2 FUCA1 CBL HPS5 SYNC TXNIP MMRN2 CD5 PICALM GATA3 AKT3 SPI1 ZNF365 FLI1 GPA33 ZCCHC24 ATL3 MARVELD1 CADM1 ST7L PTPRC SELL SELP XCL2 CD53 PRF1 ARHGDIB WASF2 PDIK1L CTSS ETV3 CELF1 RHOG EPC1 IPO7 STX5 MSANTD2 CAP1 WDFY4 RUNX3 BIN2 ZRANB1 SBF2 DUSP5 MR1 IL18 CTTNBP2NL ADAMTS4 SF1 CALHM2 ELOVL1 NT5C2 SIK3 NLRP3 EPHA2 ZDHHC5 PUM1 FCRL1 GPN2 CDC14A HIPK1 FAM53B YRDC CD69 POLR2L MAP4K2 GPR137B CAPZA1 FCGR3A OMA1 CD3E RAB39A KCNAB2 NIPAL3 GTF2H1 ARHGAP30 SRRM1 EXTL2 LAYN GNL2 FERMT3 ARFGAP2 RELT TAF5 ARAP1	down	**
GSE3982_NEUTROPHIL_VS_TH2_UP	0.0010698	0.0133921	0.4550599	-0.2997766	-1.557860	153	NOVA2 STAC SLC12A6 DENND5A FBP1 LRRFIP1 ZCCHC2 SPATA1 SLC11A1 DPEP2 SLC7A7 RAB33B DACH1 TOR1AIP1 TRAF6 CLK1 UBE2D3 EVI2B CFD KLF4 CEBPA SPAG9 SEC24B LAPTM5 CDS2 ACTR3 CAPZA2 EVI2A ARL4A GNAQ MARK3 FOXN3 NECAP1 SH3BP5 LTBP2 HK3 RAC2 TREM1 PSTPIP2 OGFRL1 APH1B	down	*
GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN	0.0013654	0.0161591	0.4550599	0.3443891	1.557662	171	HMGA2 MDM1 GMDS GABRP DEPTOR NEK2 CCDC34 TIMELESS PRIM2 DEPDC1 CDCA2 RACGAP1 C4orf19 RAD54B TYMS EME1 POLA2 ICA1 BRI3BP CKAP2L FADS2 ASF1B RFWD3 EEPD1 GOT2 TMEM8B SSX2IP SPAG5 SRD5A1 KPNB1 DNMT1 AGL ESCO2 CLTA FUCA2 KIAA1549 CCDC137 CENPM NAT8L C16orf58 ZNF446 RAI14 CKAP2 BSN CCNA2 CDH1 HDLBP RNF157 ZWILCH SCOC SOX12 TBC1D32 RNF7 POLR1A SEPHS1	up	*
MIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED	0.0050308	0.0429970	0.4070179	0.3666753	1.557560	105	CHST6 SYNPR DROSHA SLC26A8 ILDR1 DLGAP1 ASPHD2 SCG5 SPAG16 REC8 GPR182 SYCP2 RBM28 IL20RB CHAD KCNV2 KCNJ11 SPAG8 LTB4R ABHD16B KRT18 EPHA1 SPAG6 PLVAP GIGYF1 L1TD1 CNGA4 HOXA3 NSD1 IL12RB2 FSCN2 MSH4 SLC2A5 NOS1 NLGN2 VWA1	up	*
GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_DN	0.0012362	0.0149806	0.4550599	-0.2966940	-1.557182	165	FCN1 SGK3 PID1 AATK INPP5A SFR1 RBM14 PRPF38A CD36 TNFRSF8 TACC1 ZDHHC2 AHRR PARVG REV3L CYB561A3 ZNF410 CRTAM ATP10A GMEB1 MSR1 CASP1 BST1 ERP44 HPSE TLR4 ARAP3 CCDC59 PIK3R5 MARK3 IKZF5 NCOA1 RBP7 CD48 ZNF555 SNRK ASTE1 ATP6V0D1 ATPAF1 ING3 CHRAC1 TESK2 HNRNPH3 DOK2 CHMP3 CDKN1C CREBBP ANKRD49 GSG1 LPAR6 SETX JDP2 CHML TNFSF8 CCDC112	down	*
GSE360_CTRL_VS_T_GONDII_DC_UP	0.0004807	0.0071157	0.4984931	-0.2966251	-1.556774	167	CD52 PNPLA6 STAC PECAM1 OSBPL1A HHEX LTA4H LYL1 LPL EGR2 FUCA1 TGFBR2 GGA2 TXNIP UBL3 PICALM SLC19A1 CRTAM APOC1 RAB14 ADARB1 EXOSC9 EFCAB14 MSR1 TNFSF12 ZCCHC24 CPVL PINK1 HEXB NCKAP1L PRCP KLRB1 LRRTM2 PIKFYVE CAPN11 KCTD12 DNASE2 BAG5 PPM1F PLCG2 ALDH3B1 RIN2 KIAA0232 ZBTB1 CTNNAL1 ATXN1 DOK2 CLEC2B PLA2G15 RXRA GPX3 VASH1 ESYT1 S100A4 METTL7A CD1E P2RX1	down	**
GO_HOMEOSTASIS_OF_NUMBER_OF_CELLS	0.0003970	0.0061359	0.4984931	-0.2858657	-1.556296	208	EPAS1 HMOX1 TAL1 KLF13 GAPT GATA2 LIPA HCAR2 TMOD3 TGFBR3 ANXA1 SH2B3 ADA ADAM17 SLC7A11 GATA3 JAM3 RB1 SPI1 SLC46A2 MPL AXL ID2 FCER1G WDR48 LYAR INHBA ILDR2 IL7R MIR17HG ADD1 SRF NCKAP1L IL6 PKNOX1 NOTCH1 ETS1 HSPA1B DNASE2 CCR7 SKIL SP3 GPR183 GCNT4 RC3H1 RASSF2 RRN3 KLF2 FOXO3 CD74 CCR4 EPB42 JMJD6	down	**
ATGTACA_MIR493	0.0000462	0.0010150	0.5573322	-0.2793599	-1.556061	273	IL1A TTC7B SH2D3C RASAL2 CITED2 CDH13 VAMP2 SH2B3 TM2D3 PBX3 FZD4 DACH1 MED26 ITSN2 PDE4D MCL1 ZMIZ1 PTPN12 SNAI1 TLE4 FOXO1 KCNMA1 ZFAND5 TJP1 DOCK9 PPP2R5C CUL5 ZNF706 UNC5A TBC1D4 FAM76B AFF3 NCOA1 PIAS1 MTPN BTG1 SERTAD2 ETF1 FMNL2 RYBP PIKFYVE SRSF3 TMTC1 JUN JPH1 SP3 PIK3R1 MBNL2 ZNF804A COBLL1 NDST1 CELF2 SNX9 HIVEP2 PPTC7 ZBTB11 NAB1 APLP2 PHF2 ADAM10 ACAP2 LRP12 CREBBP SSH2 KPNA4 MBD5 SIN3A RNF38 KIF1B RHOT1 WDFY3 MED17 IRF2 REEP1 VPS13D CDC14A BHLHE41 SVIL ZNF385B HMGCS1 ZNF800 HIPK1 MAPK1 ITGB1 KIAA2026 CCNT2 SRSF11 XPO7 SV2B WNT5A UNC50 UBE3A ZNF362	down	**
E2F_Q6	0.0017701	0.0194825	0.4550599	0.3373540	1.555918	199	GRIA4 CDC45 GABRB3 GPAT2 CDCA7 E2F8 NABP2 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 CDT1 RANBP1 WDR62 PAQR4 AP4M1 SPTB POLA2 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 INTS7 HIRA DNAJC11 RHD POLD1 TYRO3 ATAD5 SASS6 PPP1R8 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 RAD51 ARHGAP11A KIAA0825 MXD3	up	*
GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN	0.0009065	0.0117548	0.4772708	-0.2930773	-1.555903	174	IL1A MS4A7 CCRL2 CD300E CD9 LAMP1 IER2 NFIX PTPRM BTG2 CYYR1 LITAF NR4A1 SPRY2 PDE4D LRP4 GPR4 IL10 KLF4 PLAUR ID3 ZFAND5 CCL3 ATF3 PER1 DUSP1 CD300C MAFF LACC1 SLC25A33 SLC25A25 IL6 MED28 ADAMTSL2 JUN OXNAD1 PLK3 JUNB RCAN1 PTGER4 ACKR3 FOS SPRY4 PKD2 FOSB EHD1 DUSP5 NFYC PLEKHO2 PLA2G15 FAM98B GTF2B HSPA2	down	*
GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP	0.0027463	0.0271587	0.4317077	-0.3080610	-1.555859	123	RCOR1 CD44 NEDD4L NEDD9 HBEGF KLF6 GATA3 TRAF6 CD93 SPRY2 SLC19A1 SRGN CSRNP1 KLF4 FAM49B CXCL2 ATF3 SERTAD2 ZNF330 RBPJ ARL6IP5 GZF1 SGK1 ETS1 RCAN1 PTGER4 SELENBP1 HOMER1 GPRC5A FOS SPRY4 JMJD6 TGIF1 CNOT7 ME2 CDC42EP3 ACAP2 PTCH1 SOAT1 RND1 NFKBIA JMJD1C EDN1 RORA PIM3 EGR1 CHIC2 ZFP36 DNAJB4	down	*
GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP	0.0010213	0.0129164	0.4550599	-0.2930496	-1.555459	180	GCOM1 FYN INPP5K IL1RL1 NCF2 UBL3 EIF1 RAB33B GNGT2 PPP3CA CCNI ZMIZ1 REST FAM49B CDS2 HPSE CEP57 ZBTB43 PLEKHB2 GNAQ IKZF5 CDKN2AIP AFF3 PIAS1 NRROS PIKFYVE SF3B1 CPEB4 KCTD12 IDS COBLL1 TPRA1 CELF2 AZI2 SRSF6 UBXN2A TGFB1 TFEB CD1D VPREB3 DUSP5 RNF138 SF1 SFT2D1 THAP6 TAB2 TOB2 SSH2 PLGRKT CEPT1 CD3G SKI TTC19 CYTH1 RPL18A CNOT8 BANK1 PPP1CB RABGEF1 ZNF326 DUSP6 HCFC1R1 FAM8A1 TUBA1A ATP1B1 RNF167 BCL10 RCSD1 STX16	down	*
GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_UP	0.0008911	0.0116262	0.4772708	-0.2938516	-1.555217	169	SEMA3G PTPRE SIK1 ELF2 YPEL5 RPL23AP53 ATF7IP2 TMX4 TXNIP ANXA1 DPEP2 GATA3 SLC7A2 MOAP1 CADM1 ZBTB43 DUSP1 ARL4A GNAQ MYH11 AFF1 PLCD1 NCOA1 SLC8A1 SGK1 AQP3 JUN PTGER4 THUMPD1 PREX2 TSPYL1 TNFRSF10B FOS KLF2 PTP4A1 XYLT1 FAM204A CBFA2T3 IRS2 FCGRT TOB1 RLF IQSEC1 USPL1 EPHA4 NLRP3 PTCH1 ACACB OSER1 RBM48 DNAJB9 P2RX1 RORA DAZAP2 NR3C2 PPP1CB SLC16A10 ARHGEF18 ATP6V0A1 NR4A2 ITGB1 FAM8A1 FPR1 CD69 DPF3 DNAJB1 LDB3	down	*
E2F_Q4	0.0009584	0.0122991	0.4772708	0.3367035	1.555203	202	GRIA4 CDC45 GABRB3 GPAT2 CDCA7 E2F8 NABP2 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 CDT1 RANBP1 WDR62 PAQR4 AP4M1 SPTB POLA2 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 INTS7 HIRA DNAJC11 RHD POLD1 TYRO3 ATAD5 SASS6 PPP1R8 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 RAD51 ARHGAP11A KIAA0825 MXD3	up	*
GSE10325_CD4_TCELL_VS_BCELL_DN	0.0008079	0.0107562	0.4772708	-0.2985572	-1.554521	161	KMO SWAP70 HHEX LTA4H LYL1 LY86 PLEKHF2 LMO2 GFOD1 SLC15A3 MEF2A CD1C CD22 GGA2 SLC7A7 ENTPD1 GM2A MS4A1 GNG7 TUBB6 TBC1D9 SYNPO YBX3 DENND3 CLIC4 HLA-DQA1 TBC1D5 SNX3 ARHGAP17 PKIG RNF141 JUN RHOBTB2 STX7 CD83 IRF8 CDK14 PLCG2 RHOQ IRF5 TFEB VAV3 TCF4 CD1D VPREB3 PDLIM1 CLCN6 OPN3 SPIB SCPEP1 METTL7A CD19 AIM2 EHD3 BANK1	down	*
GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_UP	0.0009040	0.0117379	0.4772708	-0.2937110	-1.554473	169	LIMS2 ACP5 PHACTR1 TRHDE FOLR1 CD44 IER2 PLA2G7 CACNA2D2 ENTPD1 MTF1 APOC1 TUBB6 TBC1D9 AHNAK PTPRO CASP1 REST PDE8A CXCL2 IGFBP2 CCND2 FCER1G HES1 HCK FLT1 IL6 TYROBP DNASE2 CCR7 IQSEC3 SKIL GPR183 POGLUT1 KLF2 TNFSF13 MBP FOXO3 GSAP TGIF1 CLEC2B CCR6 OPN3 SCN7A ICAM3 FNBP4 NFKBIA LTBP3 MT2A BANK1 LYZ	down	*
SMID_BREAST_CANCER_RELAPSE_IN_BONE_DN	0.0007997	0.0107060	0.4772708	0.3299850	1.554460	242	IGHV4-61 DKK1 CEACAM1 PTPRZ1 CA9 BBOX1 EPHB3 GALNT14 KRT5 KCNK5 GABRP S100A2 CP UCHL1 IGF2BP3 MPP6 PSPH PKP1 MUC16 PHGDH TUBB2B KRT16 IGKV4-1 AKR1C1 TBX19 SOX9 FERMT1 COCH GLDC PDE9A IGKV2D-28 LDHB TTLL4 CLDN1 IGLV3-10 KCNN4 TRIM29 IGF2BP2 PRKDC TMEM45A GPSM2 RBP1 EGFR PDZK1IP1 SOX11 PERP WNT5B PLOD2 TNFRSF21 IGHG1 TRIM2 GJB3 PSAT1 PEG10 PDK1 SRD5A1 LGR5 CRLF1 CHST3 FNDC4 TUBB2A SSRP1 S100A9 ANP32E MMP7	up	*
GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP	0.0005842	0.0083622	0.4772708	-0.2951952	-1.554351	170	HSPB7 USP12 BMPR2 BCL2A1 DNAJB14 GNGT2 LCP1 SIRPA CRK RAB14 KIF1C CSRNP1 MTMR6 VASP DENND3 VRK2 MARVELD1 IRAK2 ARHGAP9 MBD2 MARK3 CMTM6 NCOA1 HCK MTPN NCKAP1L CREBRF FMNL2 LIMD1 HRH1 GLUD1 EPC1 FBXO11 WNT11 PIK3AP1 SPOP FPR2 CD86 GNB4 STX12 PGGT1B IST1 BMP2K ITPRIPL2 RTN1 ATP9B TRAPPC8 TBC1D1 ABI3 ITCH RPL18A IQGAP1 EIF4A2 UBAP1 HERPUD1 CDC14A CX3CR1 FHOD1 ESCO1 FCRLA TES GLIS2 PIP5K1C ABCA3 USP45 IRX5 JARID2 GPATCH2L ANKH EIF4E3 IVNS1ABP MFHAS1 PPFIBP2 PYCARD FEM1C TAOK3 RNF145 TMEM127 ACRBP APBB3 MYO9B	down	**
GO_REGULATION_OF_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS	0.0051223	0.0436479	0.4070179	-0.3421733	-1.554230	70	ATXN3 CAV1 EDEM1 DNAJC3 PPP1R15B BFAR NFE2L2 RNFT1 UBQLN1 WFS1 USP25 PPP1R15A PIK3R1 UBAC2 SPOP BAG6 SERINC3 BOK DNAJB9 PMAIP1 HERPUD1 ATF6 SIRT1 DERL2 YOD1 HSPA5 PTPN1 BCL2L11 UBE2J1 DERL3	down	*
REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	0.0053484	0.0449762	0.4070179	-0.3207719	-1.553776	94	EREG KL FYN MYD88 FGF10 IL1RL1 HBEGF TRAF6 AKT3 PDGFA PIP5K1B EPGN PPP2R5C PPP2R5A CD80 PPP2CA AREG RAC2 RHOG PIK3R1 GRB2 FGFR4 KLB PIK3AP1 PPP2CB STRN CD86 IRS2 PHLPP2 FGF2 PIP4K2A CD19 KIT PTEN FGFR1 NRG1	down	*
GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN	0.0009929	0.0126449	0.4550599	-0.3021686	-1.553309	145	OLR1 ZC3H12C SNX10 SAMHD1 PAFAH1B2 IL1RN DNASE1L3 SBDS PPP1R15B ITGA5 NDEL1 SRGN ATP10A ZFAND5 TNFSF15 RMDN3 ATF3 PIK3R5 PROCR IL6 ENPP4 PCGF5 GYPC MALT1 AP3B1 HIVEP2 TREX1 SAV1 MRPL39 NAB1 SOD2 GNA13 IST1 ALDH1B1 SETDB2 ATP9B TRAF1 MAFK EDN1 AIM2 SAMSN1 MIER3 RABGEF1 SPSB1 SERPINE1 TNFSF8 SNW1 CD69 SSC5D NMI IRF1 SLC23A2 ROBO2 CFLAR NFKBIZ RNF19B	down	*
GO_T_CELL_ACTIVATION	0.0000059	0.0001786	0.6105269	-0.2669899	-1.553012	390	SIRPB1 CD55 SPN IL1B WNT4 FYN CD44 CAV1 PRKAR1A CDC42 CD1C SLC11A1 TGFBR2 IL23A CD8A RHOA ANXA1 CD5 ADA ADAM17 CLEC7A MAP3K8 FOXP1 HLX PAG1 LCP1 IFNK GATA3 PPP3CA SIRPA IL18R1 TRAF6 ZEB1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 SLC46A2 FUT7 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SFTPD FCER1G SMAD7 IL7R CYP26B1 HES1 GNRH1 SRF NCKAP1L CD8B CD80 IL6 PKNOX1 CD160 PSEN1 PDE5A RAC2 PTGER4 CCR7 SP3 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 DOCK8 AP3B1 CD7 TBX21 ZNF683 TIGIT CD151 PELI1 AZI2 RUNX3 TREX1 CD74 CR1 CD1D ZBTB1 JMJD6 CD6 LRRC32 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1 GPR18 CCR6 ICAM1 IL18 LAT FKBP1A SEMA4A RIPK2 NLRP3 CCR9 HAVCR2 ADORA2A KIT CD3G PAK2 KLRK1 TNFSF9 RORA CCND3	down	***
MORF_FDXR	0.0014234	0.0165552	0.4550599	0.3389389	1.552753	188	DDX11 FUT6 CYP19A1 PAX9 SLC2A1 ECE2 GPR35 COLQ SLC4A3 RBBP8 ALDOC PVT1 IKBKE HAUS5 WDR62 CASP2 BPHL SPTB CARD10 TPR MSX1 ERAL1 PKMYT1 HSF4 FDXR PPP5C PHB PML GLE1 ERCC2 PPIL2 DDX51 TNFRSF25 TTI1 ZNF500 TBX1 FANCG SPEF1 CDK13 PLEKHB1 SH2B1 DHRS1 CPSF4 DGCR11 WNT10B PRSS16 CYP4F12 IGHMBP2 MUSK CNTN2 NFRKB RFC5 TUBGCP4 ACKR2 PAXIP1 CHD3 ADAM15 KHNYN ILVBL MOK CYP11A1 GRIP2 NELFB CAMK2G TLN2 TUBGCP2 LTK HMG20B NCKIPSD RPS6KB2	up	*
GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0004587	0.0068577	0.4984931	-0.2933720	-1.552618	172	ACP5 SPN FOLR1 CLYBL PLEKHA1 ELMO1 ZBTB2 FAM49A PPM1N TMX4 PDE2A CACNA2D2 LATS2 PPP1R15B NAAA GM2A NFE2L2 CRTAM HERC3 APOC1 FBXO8 FLI1 ARRB1 TCP11L2 STK17B CTSD ELAC1 DUSP11 MOB3A EFR3A EMP3 TMEM9B ELF1 PLEKHA3 LIMD1 OSBPL9 FOXN2 IDNK TAGLN2 RRAS MBP ICAM2 TEC GPR18 ME2 SELPLG MOB3B SESN1 SLC35D2 C3orf38 XKR8 SETD4 GIMAP5 RIPK2 TDRP GPD1L TTC32 RBM48 MAFK CNN2 MAN1C1 SETX HERPUD1	down	**
GO_CYTOKINE_PRODUCTION	0.0000001	0.0000049	0.7049757	-0.2547178	-1.552522	608	POLR3H FFAR4 NLRC4 EREG ACP5 IL17RB IL1A HMOX1 FCN1 SCIMP SIGLEC16 CCM2L CD55 SPN IL1B FABP4 MNDA LIPA LRRFIP1 LPL JPH4 MYD88 C5AR1 IL1RL1 IL1RN GAS6 SLC11A1 NFATC3 RFTN1 IL23A FGR HEG1 APOD CD36 ANXA1 MIR146A TNFRSF8 ATP2B1 CARD16 CD33 ADAM17 CLEC7A HSPB1 RNF125 LITAF FOXP1 GATA3 SIRPA RGCC IL18R1 TRAF6 SPTBN1 CRTAM WNT3A SRGN ARHGEF2 PDE4D CD58 NODAL IL10 MAP2K3 ROCK2 ARRB1 BIRC2 MEFV CASP1 PTAFR KLF4 THBS1 CLECL1 SOCS5 LY96 FAM49B CCL3 NFKB1 CADM1 PTPRC AXL HPSE TLR4 MIR24-2 SFTPD FCER1G PER1 SMAD7 INHBA CLEC9A TGFB2 NRROS NCKAP1L RBPJ IL17D CD80 ELF1 IL6 CD160 PSEN1 APPL1 SEC14L1 NOTCH1 CARD8 TYROBP HSPA1B IFNGR1 PTGER4 CCR7 PIK3R1 CD83 IRF8 CREB1 OSM MALT1 REL SUCNR1 TBX21 TIGIT CD34 PLCG2 PELI1 KLF2 AZI2 MBP TREX1 CD74 WNT11 IRF5 CHIA TGFB1 AKIRIN2 SERPINB1 CD6 LRRC32 CD86 CD81 KLRC4-KLRK1 ORM2 NPTN GATA6 GPR18 LTBP1 PDE4B MR1 TSPO SYT11 IL18 IL18RAP ARRB2 RIPK2 NLRP3 HAVCR2 EPHA2 CREBBP TLR10 KIT KLRK1 LTBP3 MCOLN2 AIM2 FGFR1 RORA ITCH IQGAP1 PUM1 ATF4 SMAD4 BANK1 FLT4 SPHK1 CSF2 CYBA KAT5 EGR1 SERPINE1 C5AR2 ATF2 CX3CR1 CLEC4E C5 TREM2 S100A8 ZFP36 NDFIP1 TBC1D23 NFAM1 PIK3CG MUL1 POLR2L WNT5A SSC5D BCL10 AKAP12 HMGB1 DDX21 NMI EP300 CD3E IRF1	down	***
GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP	0.0004061	0.0062311	0.4984931	-0.2918865	-1.551955	175	TMEM100 TUBD1 GPR65 ST3GAL6 THAP2 MSRA LAMP1 CBL PPM1D DNASE1L3 CNST STARD4 TRAF6 CCNI KDSR CPED1 FOXO1 ACSL3 USP2 SCAF4 SPAG9 ERP44 HPSE CCSER2 ELMSAN1 MBD2 TBC1D4 NRBF2 HSDL2 MAPRE2 GLB1 MTPN EBAG9 HECA GABPA ETS1 PIK3R1 ZNF597 PPM1F CDK17 YPEL2 ZNF521 SAV1 BAZ2B VAMP4 KHDRBS1 ANKLE2 RNF138 SFT2D1 TRAPPC8 LTBP3 CECR2 ABCA8	down	**
GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP	0.0019666	0.0211630	0.4317077	-0.3066113	-1.551875	138	CXCL3 EREG PRX IL1A SASH1 DENND5A USP12 ZC3H12C RAPGEF2 STX11 BCL2A1 LIFR LATS2 MAP3K8 TTYH2 NPNT TNFSF15 DRAM1 KLF7 NFKB1 IRAK2 ZBTB43 DUSP1 LRRC3 CPLX1 RASGEF1B SNN KANK1 HESX1 DDX60L IL6 OASL STAT4 PTGER4 SKIL PI4K2B PALMD ACSL1 PELI1 GPR84 ADORA2A-AS1 GEM ARAP2 IL18RAP MIR155HG PUS10 ADORA2A MCOLN2 TNFSF9 AIM2 C21orf91 NRP2 GSG1	down	*
MIR6882_3P	0.0049641	0.0425258	0.4070179	-0.3211021	-1.551382	95	DAB1 PID1 TMEM170B SEC22C OTUD4 CBL TGFBR2 HEG1 TMX4 WWC2 MTF1 FOXP1 PRSS12 AKT3 TCF7L2 TFRC PRDM16 LIN7C AFF1 KREMEN1 CREBRF ADCY2 RAPGEF1 FRYL OSM SNRK RRN3 AKIRIN2 ANKRD13A RGS2	down	*
GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_DN	0.0016520	0.0185163	0.4550599	0.3423223	1.551262	175	CA9 TICRR DEPTOR UBE2T PSPH PBK TTK DGCR8 IFT27 CDC6 ACY1 CCT6A SDHA NUP155 MCM7 WDR78 MMS22L AKAP1 AMACR CHAF1B ORC6 CKAP2L RAD51AP1 SLC25A39 BLM GRHL2 MTG1 PPP5C DET1 CLDN15 FAM221A NPM3 SMO ILF2 CDC23 CNOT2 UROS LRRC8D GAS2 KIF20B CCDC51 CNDP2 SULT1B1 SASS6 DUS1L MUSK PATZ1 SPAG4 FARSA DDX54 RTEL1 MCU F13A1 WDR76 DNAJC10 FRMD6 SLC35G1 HGF CYP11A1 PCGF6 DLEU7 F5 TOMM7 METTL18 WDR55 PRRC1 PEX11A LCMT1 MRPL2 TIMM10 DUS3L GLRX5 TCN2 DHRS4 KLHL12 NAE1 NUDCD1 MTHFD2 QSOX2	up	*
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_PROLIFERATION	0.0047463	0.0410428	0.4070179	-0.3083717	-1.551223	111	CD55 IL1B FGF10 TGFBR2 IL23A ANXA1 CLCF1 ADA TRAF6 WNT3A TFRC BST1 CLECL1 MPL CDKN1A PTPRC TLR4 IGFBP2 HES1 NCKAP1L CD80 IL6 GPR183 PELI1 CD74 VAV3 CD1D CD6 CD86 IRS2 CD81 IL18 RIPK2 HAVCR2	down	*
GSE3982_NKCELL_VS_TH2_UP	0.0008939	0.0116499	0.4772708	-0.2980563	-1.550984	159	EDNRB WFDC1 IL1B F2RL3 PTPRE FYN CD44 FCER1A PCOLCE2 C5AR1 CLEC10A MANBA AGPAT4 FAM49A ANXA1 PTX3 GPBP1L1 STOM GPR4 CLEC1A KLF4 DRAM1 CEBPA DENND3 TPP1 NPR3 MYO15B FRMD4A IL7R SNN PROCR WASF2 CD160 KLRB1 CYB5R1 LTBP2 HK3 RAC2 AK1 ENPP4 MARC2 VAV3 TSC22D1 CDC37L1 ACTN2 RXRA ZNF143 XKR8 MFAP5 GLUL DAZAP2 NRG1 ZBTB44 DCUN1D2 UBAP1 AOAH ITGAL KCNJ1 FAM53B	down	*
GO_LEUKOCYTE_PROLIFERATION	0.0001840	0.0031956	0.5188481	-0.2841202	-1.550822	231	ACE CD55 HHEX GAPT SPN IL1B MNDA WNT4 FYN FGF10 PRKAR1A CD22 SLC11A1 TGFBR2 IL23A ANXA1 CLCF1 ADA MS4A1 IFNK TRAF6 WNT3A MAPK8IP1 TFRC IL10 BST1 CLECL1 MPL NPR3 CDKN1A PTPRC TLR4 IGFBP2 SFTPD IL7R HES1 GNRH1 NCKAP1L CD80 IL6 PDE5A RAC2 TYROBP GPR183 MALT1 RC3H1 DOCK8 CD151 PELI1 AZI2 CD74 VAV3 CD1D CD6 LRRC32 CD86 IRS2 CD81 LGALS3	down	**
GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN	0.0006138	0.0087137	0.4772708	-0.2913765	-1.550749	177	CD101 BAIAP2 TGFBR3 NEDD9 TRIB1 RFTN1 ARSB ENTPD1 BTG2 ZYG11B PPP3CC CCNI RHOB PIP5K1B MVB12B TJP1 CLIC4 FMNL3 DOCK9 CDKN1A ATF3 CCL4 RBPJ RNF149 CREM JUN HPGDS PPP1R15A PTGER4 SKIL TIGIT SNX9 SLC3A2 ATP6V0D1 MFSD10 PIK3AP1 EHD1 CD86 PDCD1 APLP2 GABARAPL1 RGS2 PDE4B ETS2 ICAM1 IER5 TOB2 ITGAE NUP98 NFKBIA GPR171 SLC16A10 HERPUD1 EGR1 PRKCH ICOS ZFP36 QSOX1 CYP51A1 DNAJB1 SPTY2D1 ARHGEF12 FNDC3A ATP2B4 NFIL3 SIRT1 NR4A3 IRF4 DUSP2 ZFP1 ADAM19 TNFRSF1B	down	**
GSE3982_MAC_VS_TH1_DN	0.0020660	0.0219840	0.4317077	0.3438211	1.550681	169	PRB3 TIMELESS DGCR8 ALDH18A1 GPI SFXN1 TFDP2 KLHDC8A PRC1 XRCC2 ORC1 GINS4 HMMR KIF23 F2RL1 KNTC1 PAFAH1B3 NUP155 ODF2 CLSPN TFR2 EIF2AK1 KDELR2 PERP PKMYT1 ERCC2 NCAPG2 NUSAP1 ASF1B DNAH6 BIRC5 GOLGA8A RBCK1 TRAF5 DNAJC7 DNAJA3 SNRPA DUSP12 TK1 STOML1 CSNK1G1 NR6A1 TSTA3 DGKA PPP1R8 CDR2	up	*
GO_REGULATION_OF_PROTEIN_AUTOUBIQUITINATION	0.0011410	0.0140834	0.4550599	-0.9894301	-1.550409	2	SASH1	down	*
WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_UP	0.0000137	0.0003640	0.5933255	-0.2711714	-1.549878	328	NLRC4 CD300LF ZNF366 SIDT2 MS4A7 CD101 ST8SIA6 SCIMP LTA4H C18orf32 FIG4 PDE1B LY86 KIAA1109 FLVCR2 ELMO1 MANBA NCF2 AGTPBP1 TET2 LAMP1 ATF7IP2 ACER3 SIGLEC6 CD36 SIRPB2 MALAT1 ASAH1 RASGRP4 GM2A IFI30 ANXA5 CYB561A3 SLC7A11 ZFYVE16 CD37 ZYG11B CCNI EVI2B SGTB MEFV CASP1 ST3GAL2 GAA SYCP2L MYO15B MGAT4A PTPRC PAPSS1 ALOX5AP EVI2A HEXB CLN8 PRCP CTSS CD48 GIMAP2 CPEB4 USO1 DNASE2 FOXN2 CSTA PSTPIP2 IDS HERC2P3 ZNF555 TRAK2 DYM NKG7 CD74 TIMP2 ZFAS1 ATP6V1A RPL21 ATXN1 NBEAL1 CSNK2A2 MR1 IL18 SLC35D2 PUS10 SLC25A20 CXCR4 ORMDL1 ALDH2 SLC2A9 AMZ2P1	down	***
GSE4590_SMALL_VS_LARGE_PRE_BCELL_UP	0.0014143	0.0164724	0.4550599	-0.2952873	-1.549799	165	DAB1 GCOM1 MS4A7 GAPT ZC3H12C CYP4B1 HCAR2 NEDD4L SLC15A3 CD8A ZEB2 PLA2G7 IFI30 LAIR1 C1orf162 RB1 SLC25A37 CD93 PDE4D FBXL5 TBC1D9 SPNS3 PTAFR PXDC1 VASP CCL3 ERP44 CCDC38 CXCL2 C9orf72 HPSE PRF1 EPS15 HCK ATP6V0B TYROBP TMPRSS11D PTGER4 ACKR3 LUZP2 NKG7 PIK3AP1 VPREB3 DUSP5 NAB1 PHF19 RGS2 IL18 LAT	down	*
GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN	0.0004780	0.0070835	0.4984931	-0.2928388	-1.549797	172	TAL1 OSBPL11 CLDND1 CLYBL NR3C1 PDCL SSTR1 RAB33B HIPK3 BFAR ASH2L CCNI PTPRO BNIP2 OSTF1 ZADH2 VRK2 NFKB1 CDKN1A ATF3 C9orf72 IGFBP2 PPP2R5A N4BP1 LMBRD1 EFR3A ZDHHC20 TDRD7 USP25 RPS6KA2 ETF1 TECR PDE6B PLEKHA3 MITF RAB31 USO1 PPP1R15A CST7 BLOC1S6 NKG7 NIPA2 TSC22D1 ATAD2B PDLIM5 SERTAD1 CHMP3 TIAM1 NFKBIA ZDHHC5 KLRK1 TNFSF9 IRF2 UBAP1 UBXN8 CHIC2 ZNF106 ENDOD1 DRAM2 PLEKHA2 CCNT2 XRN2 C6orf62 UBE2N POLR2B STARD5	down	**
GO_REGULATION_OF_ACTIN_FILAMENT_ORGANIZATION	0.0002061	0.0035226	0.5188481	-0.2838628	-1.549665	211	SWAP70 DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 TMOD3 INPP5K BAG4 KANK3 MYADM BAIAP2 CDC42EP2 ESAM S1PR1 CDC42 CIT RHOA SPIRE1 RGCC SFRP1 SPTBN1 SORBS3 ROCK2 SYNPO ROCK1 VASP COTL1 C9orf72 ACTR3 CAPZA2 PLEK DSTN ADD1 ACTR2 LMOD3 HCK MTPN NCKAP1L KANK1 MYO1C TMOD1 WASF2 SYNPO2 ARHGEF10 PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 PPM1F SNX9 WNT11 WHAMMP3 CLASP2 ACTN2 ICAM1 ARPC2 WDR1 LMOD1 CDC42EP3 TMOD2 ARHGAP18 LIMCH1 RAPGEF3 ARPC5 SYNPO2L	down	**
GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP	0.0014143	0.0164724	0.4550599	-0.2952420	-1.549561	165	HHEX LRRC8C HSD17B11 SH2D3C INPP5K P2RY13 FRAT1 RCHY1 PDE2A BEST1 TACC1 GNGT2 HLX PPP3CA RB1 CCDC82 PTPRO ID3 MARVELD1 PNRC1 LBH ELMSAN1 MYO1C PRKRA WASF2 HECA KCTD12 MSRB3 RASSF2 KLF2 WNT11 TFEB BAZ2B APLP2 ANKRD13A JUND UNC13D BNIP3L SESN1 CDC42EP3 SPIB TPT1 CD19 RNF38 CCND3 EVI5 IRF2 C1QB CNR2 C16orf95 RB1CC1 RNF167 MAP4K2 GPR137B RCSD1 SERP1 MAN1A1 FCRLA	down	*
GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP	0.0021434	0.0226533	0.4317077	0.3442888	1.548967	164	FOXM1 KCNK5 CDC45 POLQ CLGN KIF14 PMS2P5 TPX2 SLC35E3 MIS18A NCAPD2 SPDL1 CLDN1 STAG3 NUP155 VANGL1 KIF2C MPHOSPH9 GPSM2 SOX4 POLR3C KCNJ2 CKS1B NCAPG2 CBX5 HDGF C1orf112 ATIC AAGAB AP5Z1 FEN1 METTL3 SNRPE FOCAD RNASEH2A ULK1 GOLGA3 INTS7 NINL KIF22 SSRP1 ITFG2 PPME1 DHTKD1 PELO KRT8 TXNL4A CORO2A C1QTNF3 CCNA2 SMARCA4 RNF121	up	*
GSE37301_HEMATOPOIETIC_STEM_CELL_VS_GRAN_MONO_PROGENITOR_DN	0.0014143	0.0164724	0.4550599	-0.2951152	-1.548895	165	SIK1 AKAP7 HMGCR NR3C1 UBL3 NAAA PBX3 KLF10 KLF6 GRN TFRC KDSR ADARB1 MAP2K3 SDCBP SORBS1 NPNT TRIM46 ST3GAL2 UHRF1BP1L CDKN1A ATF3 HPSE ID2 CPT1A RBPJ SEC14L1 GLUD1 MALT1 LPCAT2 NIPSNAP3B YPEL2 CCR4 TEC IRS2 GALC RELL1 PIM1 ATXN1 GNB4 STX12 SPOCK2 PLA2G15 RTN4 FBXO30 TOB2 ARL14EP KIT DUSP7 EHD4 TRIM36 PMAIP1 RABGEF1 ATP6V0A1 HERPUD1 TMEM30A CCDC112 TMEM43 HMGCS1 YWHAB AKAP12 IL5 SLC43A3 ATP2B4 WDR26 DOCK5 EBI3 MYO1F FBXO33 ANXA6 IL10RA CAPG EZR ZC2HC1A TLN1 FARP1	down	*
GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY7_UP	0.0009809	0.0125230	0.4550599	-0.2926521	-1.548869	169	CPEB2 SNX10 GPR65 PTPRE RUNDC3B ARRDC4 CALCRL BMPR2 SLC39A8 STX11 ANXA1 CYP17A1 RNF182 AHNAK AIRN LEPROTL1 DRAM1 TJP1 TMBIM1 PDE3B VIM HOPX ID2 ARHGAP9 FRMD4A PRF1 ELK3 ADIPOR2 PDE1C NRBF2 ADD1 CNOT6L EMP3 MED28 MED30 ATP11A JAK1 GLIPR1 RPS6KA1 TSHZ3 TIMP2 GLRA1 POLK RXRA RBL2 YAF2 ELOVL1 ATP9B ORMDL1 ITGAE MBD5 KIT FNIP2 MMD GIMAP4	down	*
GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN	0.0039958	0.0361780	0.4070179	0.3475291	1.548758	146	TRIP13 BIK HJURP SPINK13 PRSS2 UCHL1 TM4SF18 IFI27L1 ILDR1 LAMP5 PTTG1 AKR1C1 SFXN1 TYMS MYBL2 IGFBPL1 COPB2 LILRB4 ZWINT SCG5 NME1 LGMN VASH2 HYDIN RRM2 CDCA5 SLC37A3 KDELR2 MGLL SEC61G PSAT1 PSMA5 TK1 SIL1 CEP128 CHPF KDELR3 LRRC59 PPCDC CREB3L2 PDIA4 ZNF195 FARSB SEC13 RPN1 CENPE IGLV3-19	up	*
GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN	0.0007976	0.0106830	0.4772708	-0.2922324	-1.548239	173	CD300LF SIDT2 SWAP70 PECAM1 HSD17B11 CALCRL VAMP2 NR3C1 ZBTB2 FAM49A HPS5 PDE2A ATP2B1 UBL3 GNGT2 RNF125 CSGALNACT2 FOXP1 GLS MAFG KLF7 ELMSAN1 IL7R PIAS1 FOXN3 SRF RNF141 NXF1 NECAP1 VAT1 JUNB CCR7 RC3H1 TMEM167B ACSL1 AZI2 TFEB ZBTB11 DYNC1LI1 ATAD2B INO80D SF1 SSH2 ARPC5 SKI CYTH1 FAM13B BANK1 SPATA13 CDC14A ENDOD1 LNPEP CLOCK ITGAL	down	*
GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_2H_UP	0.0045260	0.0397157	0.4070179	0.3470145	1.548093	151	HJURP NEK2 DROSHA PDCD2L NOVA1 PHF14 ZFP62 ZNF285 UMPS HNF4G ZNF850 CCDC13 ZNF485 RIPK4 RGS4 GUCY1B2 PSRC1 FRMD5 ZNF45 ZNF260 NAV2 TTI1 TNRC18 NAPEPLD ACVR1B PARS2 FANCF WDR53 ZNF234 ZNF544 GEMIN5 CCDC51 NAIF1 RMND5B SASS6 EFCAB7 CKMT2 NMNAT1 HAUS6 ZSCAN32 URB1 ZBTB9 RSPH4A INTS8 CEP85 NCDN PRIM1 DZIP3 ZNF70 RUNDC1 SLC35B3 ZSCAN29 SYNE2 MRPS26 PLXNB1 CSTF1 PAQR8 ZNF319 MLH3	up	*
GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN	0.0027376	0.0271040	0.4317077	0.3410956	1.547748	176	DDIT4 PRIM2 BRCA1 RACGAP1 ANLN NDUFS6 IFT27 CENPA ACAD9 ACOT8 CCNB2 XDH TAMM41 CISD1 KIF23 MKI67 F2RL1 PAFAH1B3 BUB1 TOP2A AURKA LMNB1 FAM162A MAD2L1 CNPY2 CKS1B NUSAP1 CDK1 BIRC5 GMNN POLR3K TRIM41 TSPAN31 EZH2 SNRNP25 DNMT1 ACBD6 ELMOD3 TUBG1 TACC3 MNS1 SLC37A4 TRIM37 HIP1R LCLAT1 POLB RAD50 CENPK CKAP5 CDC20 CKAP2 PDIA4 UNC119B RFC5 HK2 TRAK1 PGAM1 RPN1 DDX52 DTD2 LXN NCAPH CYB5B RNF14 UNC119 RCN2 LUC7L3 PLK4 CYTH3 RBL1 TMEM229B TMPO PTGR1 CCDC6 MLLT3	up	*
MIR4276	0.0002626	0.0043465	0.4984931	-0.2843525	-1.547349	220	EPAS1 KMO SGK3 OSBPL11 TRHDE SOWAHC TBX3 IL1B GPC5 SMIM12 CLEC12B QKI TET2 EOGT FAM49A TLCD2 DENND2C ZEB2 SH2B3 RRAGC ASAP1 HECW2 CSGALNACT2 GATA3 RB1 AKT3 ITSN2 UBE2D3 PTPRO MPEG1 TSPAN12 AFAP1L1 NR1D2 SIK2 USP44 ZBTB43 CYP26B1 RASGEF1B PRDM11 VPS37A INPP5B APPL1 HECA C20orf194 CNTN4 TBC1D12 FERMT2 RC3H1 ACSL1 EMC7 KIAA0232 SBF2 TSC22D1 NAB1 IFNAR1 ADAM10 CALB1 B3GALNT1 SETDB2 USPL1 TMOD2 CAMSAP2 RORA MIS18BP1 ZFYVE26 PLAG1 CSF2RB CDC14A CDKN1B EXOC8 TBC1D23 PLXDC2 CTDSPL2	down	**
YANG_BCL3_TARGETS_UP	0.0004311	0.0065176	0.4984931	0.3253019	1.546814	279	MMP13 TF PLAT FOXM1 KIF20A PARPBP ELOVL6 CP CCNB1 UBE2T PBK CDCA2 RACGAP1 TRAIP IGFBP6 NDUFS6 AURKB PTTG1 ECT2 ESPL1 CCNB2 LSR PRC1 LRRC27 CXCL10 MKI67 KNTC1 BUB1 TOP2A AURKA KIF2C COASY RRM2 LIPE PEX6 B3GNTL1 HPR RAD51AP1 KHK BACE2 CKLF NRTN TNIK KNSTRN CDKN2C NUSAP1 IGFBP5 CDK1 TNFRSF21 MERTK E2F1 CTXN1 STAT2 DGAT2 SDCBP2 SAPCD2 RTP4 RAPGEF5 CPT1B IRF6 MOV10 DLGAP5 TACC3 KIF22 SLC37A4 KIF20B SPA17 SMIM22 CEP128 PTN ABCC9 CDC20 NAT8L CKMT2 CENPT CKAP2 RAB15 PARP14 PFKFB4 CH25H MYH3 CCNA2 DTX3L TXNL4B SYBU PCSK5 PFKM ARHGAP11A SCOC GBP2 GNA14 VWA1 ABO GPX7 UBE2C RASGRP1	up	**
GSE14000_4H_VS_16H_LPS_DC_UP	0.0009300	0.0120174	0.4772708	-0.2966615	-1.546580	156	EPAS1 ZC3H12C LTA4H SAMHD1 RTN3 MSRA MKNK1 CBL SPCS3 DNASE1L3 CD33 BTG2 PARVG REV3L GPBAR1 GPM6A EFCAB14 SCP2 LIMS1 RRM2B KLF9 GAPVD1 PLEKHB2 HTT MPC1 UBASH3B ACTR2 ZNF426 TBC1D5 TECR FLT1 OASL SNX29 GLIPR1 ATP13A3 HOMER1 NIPA2 OSGIN1 TPMT ATXN1 MBNL1 RXRA ABL2 IQSEC1 RAB5A ESYT1 MEGF9 RPS13 S100A4 TMX2	down	*
GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP	0.0025518	0.0257626	0.4317077	0.3436678	1.546571	163	LTF ZDHHC4 CHODL SLC5A1 SAYSD1 C4orf19 ACY1 SPDL1 ZNF862 PCCB KNTC1 P4HTM MCM3 MCCC2 THYN1 TBC1D8 RABEP2 REPIN1 BLM SLC35E2B NAA40 TNIK TMED3 FASTK UCK2 ATIC KCTD13 TRAPPC12 NRGN G6PC3 DNAJA3 UROS PIGG PPOX SCNN1G TCEA2 KDELR3 MRPS33 USP21 HAX1 MMP24 POLR2I CCNG1 HAUS4 ENOX1 SPON2 PRIM1 SCNM1 TTC31 WDR77 TRAPPC9 RSAD1 DHRS3 MRPL48 ACAD8 MAP2K2 NCAPH CLNS1A INPPL1 SHQ1 CXorf40A AXIN1 TRAFD1	up	*
GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	0.0006494	0.0091132	0.4772708	-0.2878810	-1.546555	189	SMAD6 ACVRL1 SOSTDC1 SFRP4 GREM2 BMPER BMP2 CDH5 ENG FOLR1 CAV1 CITED2 BMPR2 FGF10 TGFBR3 TGFBR2 TMPRSS6 LTBP4 ADAM17 CAV2 SFRP1 SPTBN1 ZEB1 NODAL PRDM16 SDCBP NPNT ZNF423 DAB2 THBS1 SMAD7 INHBA VEPH1 HES1 HTRA4 MIR17HG TGFB2 NRROS RBPJ ADAMTSL2 MAGI2 NOTCH1 BMP3 SKIL FSTL3 UBB TGFB1 TGFB1I1 MYOCD TOB1 LTBP1 SMAD2 LDLRAD4 FKBP1A CDKN1C DACT2 CREBBP ING2 SKI SMAD4 SKOR1 GREM1 DKK3 CD109 NOG SNW1 CTDSPL2 WNT5A EP300 RNF111 WWTR1 GDF7	down	**
GCM_MAP4K4	0.0013558	0.0160830	0.4550599	-0.2958724	-1.546367	162	RDX CLDND1 CCDC88A KIAA1109 BMPR2 ARL8B AGPAT4 ZEB2 DNAJB14 UBL3 TTL SPIRE1 TTYH2 ABHD6 EPB41L2 LRP4 ADO RMDN3 SPAG9 PEAK1 FMNL2 IL17D GZF1 RNF141 HMBOX1 PHF10 DDX17 MAP4K4 IPO7 FRYL PDZD2 NAA30 OCIAD1 CALM1 NAPG DDHD2 MTMR2 PPIG WBP2 STX12 NPTN CLASP2 MACF1 PHLPP2 GLTP RTN4 TMOD2 SIK3 IPO5 ULK2 CCDC92 MTUS1 KIF1B RNF13 TMEM30A HIPK1 SH3GLB1 DYNC1I2	down	*
GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP	0.0005904	0.0084372	0.4772708	-0.2946233	-1.546268	167	SLC12A6 PHACTR1 SPNS1 EGR2 PLEKHF2 BMPR2 GIMAP6 LAMP1 CD22 MTF1 FOXP1 HIPK3 CD93 LAMTOR3 ATP6V1B2 CST3 LRRC57 TCP11L2 MAP1LC3B ARNTL LAPTM5 N4BP2L1 CNOT6L NCOA1 CREBRF ELF1 SGK1 RHOBTB2 CPEB4 RAC2 ATP6V0B OSTM1 PTGER4 CCR7 IRF8 GMFG COBLL1 STX5 DOCK8 SNRK CELF2 ATP6V0C C8orf37 GPR18 ADAM10 TXNDC15 NT5C2 TMEM184B COMMD8 SNAP29 ANXA11 FCRL1 IRF2 EGR1 PXMP4 ITGAL FAM8A1	down	**
MIR301A_3P	0.0000223	0.0005486	0.5756103	-0.2711767	-1.546185	337	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 MCTP1 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 PXK ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	***
MIR301B_3P	0.0000223	0.0005486	0.5756103	-0.2711767	-1.546185	337	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 MCTP1 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 PXK ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	***
WIERENGA_STAT5A_TARGETS_DN	0.0009321	0.0120322	0.4772708	-0.2951305	-1.546119	157	SMAD6 FCN1 GCSAML PECAM1 GAPT WFDC1 FCER1A GFOD1 STX11 CD9 DENND2C JAM3 CD93 ROCK2 PTGIR SPNS3 CLDN5 MPL COTL1 SELP ARAP3 FCER1G SBDSP1 WASF3 PLEK UBASH3B VWF RGS18 CAPN11 NOTCH1 ETS1 MSRB3 IRF8 PSTPIP2 OGFRL1 PPM1F PLCG2 GJA4 DOK3 PDLIM1 IRS2 CTIF MEIS1 PLEKHO2 LDLRAD4 VASH1 CGRRF1 CXCR4 SCPEP1 ADORA2A BANK1 LYZ TREML1 C5 LHFPL2 ZYX PLXDC2 EFNB2 GNG11	down	*
GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_UP	0.0011815	0.0144779	0.4550599	-0.2912817	-1.546075	180	SLC6A4 SWAP70 MS4A7 LY86 LONRF1 ALAS1 BCL2A1 NCF2 GALNT18 SLCO2A1 ANXA1 CLEC7A IFI30 LITAF CYB561A3 SERPINB9 GRN SFRP1 SRGN CST3 FABP5 DUSP3 CCL22 AHNAK GRK5 GMPR AXL FCER1G PLEK ACTG2 MYH11 HLA-DQA1 HEXB ATP6V0B HSPA1B STX7 CD83 IRF8 PSTPIP2 LPCAT2 OGFRL1 SERPINB1 TEC TSC22D1 CD86 GNB4 APLP2 LGALS3 DECR1 TAGLN DBNDD2 ICAM1 PARM1 CDC42EP3 ISCU S100A4 NRP2 GRB10 EHD4 RNH1 PAPSS2	down	*
GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN	0.0016018	0.0181059	0.4550599	0.3380577	1.545724	186	PAGR1 MPP6 NDC80 BRCA1 GMPS GINS4 CCT2 MELK CISD1 KNTC1 PUS7 LARS2 COASY RBM28 AIMP2 EMG1 KDELR2 DNAJC9 CAD PHB IDH2 DDX56 HDGF POLE2 CCT3 PSMB5 MCAT MRPS2 NEIL3 PSMC4 RTP4 KPNB1 RANGAP1 DNAJC17 DPP3 GSS LONP1 CASP7 ANAPC1 FHL2 CCT7 RAD50 RNF187 ORMDL2 PPP1R8 HMGA1 FAM136A HEATR1 DUS4L RCC1 GLO1 DOHH BLVRB NDUFA8 CDK5 CENPE PPIA NCAPD3 RAD1 DDB2 NAT10 DNM1L ILVBL PPP1R14B ACSL5 PRKAG1 ERLIN1 CYB5B CD38 RNF14 AVEN MUS81 CLPP RWDD2B TMPO BATF TEFM	up	*
GSE16755_CTRL_VS_IFNA_TREATED_MAC_DN	0.0005036	0.0073996	0.4772708	-0.2920028	-1.545372	172	SLC31A2 DENND5A MYD88 STX11 EDEM1 ATP2B1 ADA TNIP3 SERPINB9 PPP2R2A UBE2D3 PDGFA ATP10A PPM1K GMPR CDKN1A CCSER2 N4BP1 IL7R TDRD7 SRGAP2C DCP1A HESX1 IL6 PSEN1 SOCS3 MAML2 RAB8B STAT4 ELOVL7 IQSEC3 FSD1L RNF24 DENND4A GFPT2 PELI1 HIVEP2 ADPRM SAV1 AKIRIN2 TEX30 DUSP5 SOD2 ICAM1 RNF138 C3orf38 TNFAIP8 NBN IER5 LRP12 TRAF1 NFKBIA MCOLN2 TNFSF9 SSB OSGIN2 ASH1L-AS1 LAMP3 FAM160B1 WNT5A NMI IRF1 PTGS2 NCOA7 MSC EBI3 RNF19B SLC25A28 CDC42EP4 IL10RA FEM1C SLC5A10	down	**
AKT_UP_MTOR_DN.V1_DN	0.0026715	0.0265934	0.4317077	0.3452975	1.545319	155	COL17A1 CPLX2 BDH1 PROM1 COIL JPH3 PKP1 IRS1 ACY1 MOCOS SMARCD3 KCNN4 POLM PUS7 ZNF112 POLD2 MSX1 CHAD SARS2 ASS1 CBY1 MGAT4B TULP3 HARS2 MERTK TYW1 STEAP1 PSAT1 KRBA1 DNAJA3 SLC37A4 COL5A2 CENPQ MSRB2 AGPAT5 CADM3 MCM6 PLEK2 UTP20 LANCL2 RTKN IL7 STAB1 CAP2 CDC42BPA BLVRB VPS33B GNA14 MTHFD1 KCNAB3 PARP2 ISYNA1 ZC3HC1 DPYD ZNF771 CES2 AP2B1 FMO3 TYMP RPS6KB2 MRPS6 CDPF1 SHMT1 TIPIN IL17RC	up	*
GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP	0.0017449	0.0192295	0.4550599	0.3418393	1.545110	170	NOVA1 STK36 ANKZF1 GMPS DGCR8 TFDP2 EXOC3 MIS18A CCDC77 RFXANK ZNF174 SETDB1 ZNF226 IFT172 SLC25A39 TRMT2A PRMT6 NCAPG2 KIAA0556 EEPD1 LRRC37A2 NRGN EFTUD2 INTS7 CNOT2 FOXRED1 TACC3 DHRS4-AS1 PLEKHG7 MTA3 LRRC8D CCDC159 NADSYN1 NIF3L1 CCDC137 NAGS FAM50B PPP1R3D MRPL41 MCM5 WDR35 LANCL2 PYGO2 PRKD2 MVP ZNF519 COG5 RRNAD1 RBM42 ZNF436 COX5B RNF123 PFKM RHOT2 ADRM1 LXN APEH TOP3A TYK2 SLC2A4RG PRCC KCNK1 SHKBP1 XRCC5 DHX38 MEN1 BBS12 GLCE MSH3 TTC38 PRRG4 BUB3 RALGAPA2 CHCHD5 RABGGTA SUSD3 TXK USP32P2 EMC10 RALGAPB	up	*
GO_SECRETORY_GRANULE	0.0000001	0.0000063	0.6901325	-0.2514414	-1.545092	636	SIRPB1 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 IL1B MNDA CLEC3B LTA4H SNX10 CAT RAB44 CLEC12A IZUMO1 PTPRB OSCAR MMRN1 CD44 CTSW CAV1 BAIAP2 CHIT1 CYB5R3 VAMP2 PAFAH1B2 TBXA2R C5AR1 YPEL5 CDC42 MANBA NCF2 VAPA CD9 FUCA1 GAS6 LAMP1 SLC11A1 LILRB3 FGR RHOA CD36 SLC44A2 DNAJC3 MAN2B1 CD33 ARSB ASAH1 RAP1A GM2A ANPEP CAV2 PTX3 STOM LAIR1 SIRPA CD93 GRN LAMTOR3 SRGN PDGFA RAB14 CD58 CST3 FABP5 CFD EXOC3L1 SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 THBS1 STX3 ATP6V1D MYRIP FAM49B ABCC4 SPAG9 CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL SELP HPSE ARC ARHGAP9 CD53 FCER1G GCA DEGS1 ANXA3 CMTM6 VWF ACTR2 TGFB2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP VAMP3 CTSS PSEN1 PHACTR2 EBAG9 SNAP23 CYB5R1 CAPN11 VAT1 NOTCH1 RAB31 SFTPB HK3 CTSZ TYROBP HSPA1B ATP11A RHOG STX7 SKIL ENPP4 GLIPR1 GMFG SERPINB6 CAP1 PRKACA TCP1 FSTL3 PSMD12 ALDH3B1 BIN2 CR1 MME CPA3 TIMP2 STXBP3 SIGLEC14 TGFB1 TMX3 DOK3 SFTPC SERPINB1 FPR2 CDC37L1 TSPAN14 DYNC1LI1 ATP6V0C SLIRP GPR84 APLP2 LGALS3 ORM2 BRI3 ACTN2 PLEKHO2 CSNK2A2 ADAM10 IST1 COMMD9 TCTEX1D4 UNC13D	down	***
GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS	0.0004655	0.0069433	0.4984931	-0.2905857	-1.545038	175	LPIN2 PPARG CPEB2 IL1B PTPRE PID1 KL PCSK9 LPL INPP5K BAIAP2 VAMP2 ATP2B1 CAV2 ADIPOR1 NDEL1 ATP6V1H ATP6V1B2 FOXC2 RAB12 FOXO1 SRSF5 SORBS1 ATP6V1D PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 SLC25A33 PDK4 KANK1 MYO1C SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 RAB8A ATP6V0D1 RHOQ FOXO3 ATP6V1A IRS2 ATP6V0C	down	**
GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP	0.0007150	0.0097967	0.4772708	-0.2950431	-1.544803	166	SMAD6 CXCL3 HMOX1 FABP4 BMP2 GTF2E2 AQP9 C5AR1 SLC11A1 ZBTB2 FGR KCNAB1 WWC2 SLC44A2 SH2B3 ENTPD1 PLXNA2 ITGA5 COX18 STOM RGCC SLC19A1 PPP3CC MSR1 MAP2K3 NES UBQLN1 CADM1 VIM HOPX IL7R PEF1 TANC1 PROCR NINJ1 PDK4 PHTF2 ESD RAB8B SLC35E4 INMT PLK3	down	**
GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN	0.0006755	0.0093914	0.4772708	-0.2904503	-1.544781	184	HSD17B11 DDX6 NEDD4L AQP9 SRSF7 VAMP2 PLEKHA1 LAMP1 HSPE1 EIF1 EIF5 NLK ABCG1 KLF6 PRSS12 GATA3 RGCC ADRB2 RHOB ARRB1 KLF4 NR1D2 SELL PNRC1 CCND2 DUSP1 SMAD7 IL7R BTG1 RBM39 CTSS SOCS3 RNF141 DDX47 JUN NOTCH1 KCTD12 GSTO1 CCR7 PABPC4 DDX5 CD7 DYM DEDD SLC3A2 FOS MBP FOSB NR2C1 PIM1 TOB1 KANSL2 RGS2 ETS2 JUND SESN1 PCM1 TDRP TRAF1 RNF38 SKI MCOLN2	down	**
GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_DN	0.0007150	0.0097967	0.4772708	-0.2949160	-1.544138	166	HSPA12B IL17RB BMP2 ARRDC4 BDNF STXBP6 KANK3 MANBA IL1RL1 PEAR1 SPCS3 EDEM1 KCNK3 ENTPD1 ZDHHC2 AHRR PBX3 PPP2R2A ANKRD29 EFCAB14 PER3 NRARP BST1 GAA ARNTL BCHE C9orf72 AXL HPSE ATP6V0D2 MBD2 N4BP1 UBASH3B PPIL4 METAP1 NDNF PNPLA8 PSTPIP2 WDR7 CCR4 TIMP2 EHD1 NIPA2	down	**
GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP	0.0030481	0.0294832	0.4317077	0.3450176	1.544048	156	PDE11A CA9 HP DEPTOR NEK2 CENPF WFDC2 COL27A1 PHGDH CDK4 RACGAP1 TRAIP DIO2 PAK6 XRCC2 ALDOC TMEM41A SMARCC1 KIF23 STAG3 BUB1 MDFI CHAD ANKRD13B CHAF1B LMNB1 MCCC2 PDZK1IP1 ORC6 INCENP CBX5 HDGF E2F1 NCAPG GDAP1L1 DGCR6 MOV10 OR10AD1 CCL21 LMNB2 AARSD1 DNM1 SGSM3 C12orf73 ATAD5 RAD50 KRT8 CKAP2 ODF3B LSM7 RTKN GAD1 CHRNA5	up	*
GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP	0.0006467	0.0090791	0.4772708	-0.2901095	-1.544006	177	ADPRH CPEB2 LPXN KIAA1109 MYD88 GNPTAB ZBTB2 ABCB1 CSRP1 COX18 KLF6 M1AP ABHD6 PPP2R2A ARHGEF2 TXN CST3 SLC7A8 CLIC4 CDKN1A NR1D2 PNRC1 WDR48 INSL6 KREMEN1 PIAS1 ST6GALNAC6 USP25 SGK1 PPP1R15A CCR7 MORC3 HOMER1 OGFRL1 TAGLN2 TPRA1 POGLUT1 CD164 ICAM2 MARC2 SPOP STXBP3 MTMR2 HBP1 ACYP2 NR2E3 PDLIM5 SERTAD1 NSUN4 TRAF1 FNBP4 SIN3A NFKBIA THRAP3 CYTH1 AIM2 EHD4 CNN2 BMI1 JDP2 SERPINE1 TNFSF8 TMEM30A NR4A2 ENDOD1 CRBN	down	**
GO_LEUKOCYTE_MIGRATION	0.0000080	0.0002304	0.5933255	-0.2665804	-1.543122	395	ANGPT4 CXCL3 IL1A HMOX1 SWAP70 TEK CXCL16 GCSAML OLR1 GPR15 EDNRB PECAM1 ADTRP SPN IL1B THBD FYN CD44 CCL3L1 CAV1 ESAM C5AR1 S1PR1 CDC42 CD9 IL1RN GAS6 IL23A RHOA APOD ANXA1 PLA2G7 IGKV2-28 ADA SLC7A7 SBDS ADAM17 ITGA5 SLC7A11 GATA3 JAM3 SIRPA CRK PDE4D CD58 IL10 CCL22 PTPRO BST1 PTAFR FUT7 ROCK1 SLC7A8 THBS1 CCL3 ITGAX CXCL2 SELL SELP CCL4 JAM2 MIR24-2 SFTPD XCL2 FCER1G DUSP1 OXSR1 AKIRIN1 TGFB2 HCK NCKAP1L IGLV2-11 FLT1 IL6 CD48 LRCH1 HRH1 RAC2 TREM1 RHOG PTGER4 CCR7 DAPK2 PIK3R1 GYPC GRB2 GPR183 DOCK8 CXCL5 TNFRSF10B TBX21 IGKV3-20 CD34 SLC3A2 CD74 TGFB1 VAV3 ITGA9 VPREB3 FPR2 MIA3 CD81 LGALS3 DOK2 KLRC4-KLRK1 IGHV3-23 CCR1 GPR18 ADAM10 PDE4B IGKV1D-39 CCL20 CCR6 ICAM1 SELPLG	down	***
chr20q11	0.0045755	0.0400402	0.4070179	0.3558298	1.542986	122	DNMT3B TPX2 VSTM2L ARHGAP40 UQCC1 CEP250 KIF3B BPIFB1 RPS3P2 SNHG11 AHCY SNORA71D BPIFB9P TTLL9 E2F1 CPNE1 TTI1 FER1L4 CBFA2T2 EIF6 POFUT1 NFS1 GSS COMMD7 HM13-IT1 PDRG1 TM9SF4 EFCAB8 RPRD1B BCL2L1 BLCAP PIGU ROMO1 SNORA71A MMP24 MYH7B ERGIC3 SPAG4 SNORA60 MANBAL CDK5RAP1 RNU6-759P MAP1LC3A ZNF341 ACTR5 TRPC4AP DSN1 RBL1 ITCH-AS1 SNHG17 ASIP DUSP15 DLGAP4 SNTA1 CDC42P1 NCOA6 GGT7 HM13 SNORA71C SNORA71B FOXS1 SRC RALGAPB MIR4755 PLAGL2	up	*
GSE36826_WT_VS_IL1R_KO_SKIN_UP	0.0006227	0.0088099	0.4772708	-0.2939432	-1.542698	167	ACP5 FABP4 CYP27A1 HSD17B11 CRY2 CLEC10A DPEP2 NAAA ABCG1 SLC7A11 APOC1 CST3 EPB41L2 FLI1 CYBRD1 CFD PER3 SRSF5 KCNMA1 CPVL CTSD ITGAX WDR48 CLIP4 HLA-DQA1 PI4K2A VWF STK24 BTBD18 MYLIP BCAR3 CTSS MITF DNASE2 PABPC4 COBLL1 RNF146 FOXO3 TCF4 CD86 IRS2 HBP1 CD81 RGS2 CLEC2B SEMA4A CEBPD TPT1 CXCR4 CDKN1C ISCU LTBP3 LYZ ZBTB40 CBX7 ACSM5 BHLHE41	down	**
GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN	0.0006227	0.0088099	0.4772708	-0.2991815	-1.542348	149	IL1A FCN1 TRHDE IL1B F2RL3 GREM2 PTPRE CDC42EP2 CDC42 PDE4C PILRA RHOA BTG2 MCL1 MYOZ3 MAP2K3 CASKIN2 HAUS2 PLBD1 HPSE KCTD20 TLR4 PRF1 WASF3 OXSR1 CA1 TAF13 EMP3 HECA MTMR14 ETS1 PPP1R15A TNFRSF9 RASSF2 ZNF407 BIN2 MME EHD1 JMJD6 TESK2 FPR2 TERF2IP RGS2 CES3 IQSEC1 CYB5R4 KCNJ9 SYNPO2L FLT4 SETX FHL5 CHIC2 AKTIP OSGIN2	down	**
GO_REGULATION_OF_MITOTIC_CELL_CYCLE	0.0000068	0.0002002	0.6105269	0.3090862	1.541750	548	HMGA2 MCIDAS TRIP13 CEP72 BRINP1 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 CENPF STOX1 NDC80 BRCA1 TTK CDK4 SMPD3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN NABP2 CEP70 PLK1 AURKB PTTG1 ESPL1 CDC6 TPX2 TFDP2 PRKCA CDC25A ORC1 DTL ZFYVE19 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 CASP2 HMMR BTRC SMARCD3 DLG1 NLE1 FOXA1 MKI67 CUL9 CUL7 KNTC1 BUB1 LGMN TOP2A AURKA EME1 ODF2 SFI1 TPR MAD1L1 CLSPN TTLL12 CDCA5 PRKDC FSD1 TOM1L1 KIF11 GPSM2 CDC25C SOX4 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 MDM2 PKMYT1 BLM PML CNOT3 ERCC2 PSRC1 PTPN3 INCENP CKS1B AFAP1L2 CDKN2C NUSAP1 ANAPC5 CTDSP2 CDK1 CEP97 CENPJ RFWD3 E2F1 PSMB5 TMEM8B ANAPC7 EZH2 CNOT11 EGF MTBP PSMC4 MAD2L2 KLHL22 FGFR1OP CEP63 CCNE1 CEP192 CDC23 TUBG1 DLGAP5 CNOT2 PSMA5 NINL TACC3 RAD9A PSME2 MTA3 FZR1 KIF20B ASNS ANAPC1 CDK13 PSMD2 ATAD5 CDC7 SH2B1 CKAP5 PSMB3 CDC20 GBF1 BCL2L1 CHMP4C WNT10B CDK5RAP2	up	***
GO_REGULATION_OF_SEROTONIN_SECRETION	0.0023333	0.0240767	0.4317077	-0.9838149	-1.541610	2	SLC6A4	down	*
GO_RESPONSE_TO_ORGANOPHOSPHORUS	0.0022415	0.0233494	0.4317077	-0.3081851	-1.541379	115	SLC6A4 GPD1 TEK IL1B P2RY1 RAPGEF2 THBD TRPC3 INPP5K FOSL1 AQP9 PDE2A RAP1A BIRC2 PTAFR SSH1 P2RY2 SELL PER1 DUSP1 MMP19 SLC8A1 AREG JUN DUOX1 JUNB RAPGEF1 FOS PKD2 FOSB	down	*
GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_UP	0.0053306	0.0448708	0.4070179	0.3577108	1.540927	115	PDE11A PTPRT FGA FUT6 KRT5 ADRA2A STAB2 PPP1R14D ECE2 ALDH1L1 SLC4A3 B4GALNT1 SYT12 NPFFR1 SLC6A20 STRA6 GPR37 F2RL1 TRIM29 HAVCR1 RAD54L SALL2 NEK11 THPO NRSN2 ASF1B TRIM2 CDH3	up	*
TAATAAT_MIR126	0.0008884	0.0116135	0.4772708	-0.2908408	-1.540866	173	RASAL2 VAPA TSHZ1 ZBTB2 ERG SEMA6D ATP2B1 HECW2 LDLRAD2 BZW1 GPBP1L1 DACH1 TFEC PTPN12 CLEC1A PPP6R3 DENND6A RUNX1T1 UHRF1BP1L SPAG9 PNRC1 PLEKHB2 ZMPSTE24 MPC1 STK24 FOXN3 GPBP1 HECA JPH1 PRKCE COBLL1 AP3B1 GRIK1 CELF2 TSHZ3 ING3 AZIN1 AP1G1 SKIDA1 ATP6V1A C16orf72 MAP3K2 KAT2B PRDM8 RNF138 ZNF583 KPNA4 CEPT1 EIF4A2 PURB PLAG1 GHR BHLHE41 DCUN1D3 NDFIP1 PDE7B HMGB1 MAN1A1 ARHGEF12 CUL2 FNDC3A MEF2D NR5A2 NKD1 RAB11FIP2 MAT2B NDUFAF3 LRP1 ARGLU1 SRRM1 ERLIN2	down	*
MORF_SOD1	0.0007219	0.0098698	0.4772708	0.3281532	1.540782	236	PDCD6 CCNB1 COA1 GGCT CDK4 EIF3B XPOT CCT2 DCTN2 NME1 RUVBL2 SDHA EEF1E1 CCT5 CBX3 NDUFS2 MRPL3 AIMP2 FBL ETFA TMEM106C ANAPC5 SSBP1 CCT3 ATIC UNG SEC61G KIF2A LARP1 FEN1 KXD1 SNRPE DAP VBP1 ILF2 CDC23 SNRPA SLC4A2 CCT7 STOML2 ACLY RPA1 TBCA PRMT1 TMEM147 SRSF1 HAX1 POLR2I LSM4 PSMB4 NEDD8 ALG8 NDUFV1 AP2S1 GLO1 MSH2 DOCK3 BANF1 VDAC1 PRPF31 ATOX1 TPGS2 SEC13 FBXW11 MRPL9 SRP9 SNRNP200 NDUFS8 UBAP2L MTHFD1 CHERP TBL3 GPN1 SF3B2 SART3 MAP2K2 LYPLA1 CLNS1A AKR7A2 DRG1 DGUOK UTP18 FAM120A HUWE1 NHP2 CS HNRNPAB LRPPRC SRSF9 PPP2R1A CALM3 COX6A1 DDX49 FIBP PSMD8 ACOT7 COX6C PPM1G BUB3 ATXN10 RAC1 TRIM28	up	**
MIR196A_3P	0.0024383	0.0249191	0.4317077	-0.3082733	-1.540424	107	EPAS1 AATK SEC22C CORO1C TEX2 SPIRE1 SLC25A37 SPTBN1 DUSP3 C9orf72 CUL5 ADD1 SEC31A SRF INO80C MED28 USO1 MSRB3 RABGAP1 FOXN2 ATL2 MSANTD2 PTP4A1 FOXO3 MAPK8 PBRM1 ATXN1 PPP3R1 ANKRD13A INO80D	down	*
GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_UP	0.0009843	0.0125601	0.4550599	-0.2927996	-1.540060	164	GPD1 OLR1 USP12 IL1B PTP4A2 SLC39A8 MAL SLC11A1 CD8A HSPE1 WNT2B LITAF STOM CLK1 BTG3 TXN TRPC2 CFD HNRNPA3 SOCS2 CCL3 NFKB1 SELL INHBA KLRD1 MBD2 N4BP1 PTGIS CRIM1 BTG1 NINJ1 IL6 KLRB1 STAT4 PPP1R15A WTAP CCR7 HERC2P3 ENTPD4 DENND4A CELF2 FOXO3 PPP2CB EHD1 CCP110 PIM1 SOD2 ANKRD12 ICAM1 BNIP3L CXCR4 TOB2	down	*
GO_MYELOID_LEUKOCYTE_DIFFERENTIATION	0.0005679	0.0081660	0.4772708	-0.2894610	-1.539211	176	CD101 TAL1 PPARG GATA2 SNX10 DCSTAMP OSCAR PDE1B CDC42 TGFBR2 TRIB1 LILRB3 IL23A KLF10 FOXP1 GATA3 RB1 TRAF6 SFRP1 SPI1 TFRC EVI2B CEBPA CCL3 ID2 TLR4 FCER1G INHBA UBASH3B PAFAH1B1 NRROS RBPJ PSEN1 JUN MITF CUL4A TYROBP JUNB OSTM1 CCR7 SP3 PIK3R1 GPR183 CREB1 SIGLEC15 FSTL3 RASSF2 FOS CD74 TGFB1 CBFA2T3 CD81 CCR1	down	**
GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_UP	0.0049022	0.0421222	0.4070179	0.3535779	1.539079	124	CDHR2 BHMT AP3B2 CHEK2 DNAJC22 DEPDC1B C6orf141 ASIC1 FA2H ANKRD24 LAMP5 CCNB2 CYP27B1 ARHGAP33 CDC25A EME1 AGT ADM2 AMACR MYRFL C22orf46 FDXR FUT2 BMP5 C2orf50 SPATA6L DMGDH CDH3 EFCAB1 LINC00649 CPXM1 EVC2 FER1L5 COL9A2	up	*
E2F1_Q3	0.0011927	0.0145805	0.4550599	0.3319278	1.539044	207	GRIK2 GRIA4 GABRB3 CDCA7 E2F8 NABP2 CDC6 E2F3 GAPDH SLITRK5 MCM2 CDC25A ORC1 C19orf57 MCM8 CAND1 EPHB1 WDR62 PAQR4 KIF15 AP4M1 SPTB CACNA1G MCM7 CLSPN RRM2 MCM3 TOPBP1 DNAJC9 DCTPP1 PKMYT1 CNOT3 CDK1 POLE2 PHF12 GMNN E2F1 EZH2 THAP8 ZNF827 DNMT1 ZNF687 ACBD6 PELP1 NDUFA11 HIRA EPHB2 PCSK4 POLD1 TYRO3 ATAD5 SASS6 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 OVOL2 STK35 ATAD2 NUP62 MSH2 YBX2 ABCF2 ARHGAP11A MXD3 E2F7 RABL6 ZNF367 NELL2 LASP1 LUC7L3 ADAMTS2 PLK4 RBL1 FBXO5 TMPO FMO4 SHMT1 ZNF524 TIPIN MTF2 SIX5 GPRC5B PAN2 KLF5 POLD3 RAVER1 STMN1 RMI2	up	*
GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_DN	0.0014240	0.0165553	0.4550599	-0.2977202	-1.539023	150	SLPI SASH1 ABHD5 ENDOU IL1B MNDA DCSTAMP ARHGEF15 AATK AQP9 P2RY13 BCL2A1 IGSF6 LITAF SLC7A11 LHX6 TNS1 ATP6V1B2 SDCBP MEFV BST1 DRAM1 STX3 DENND3 PLBD1 LY96 ITIH5 P2RY2 CTBS TLR4 ARAP3 GCA LMBRD1 HCAR3 RNF141 TREM1 IFNGR1 APH1B RALB CDK14 DGKG MME TFEB SOD2 STON1 NRN1 FGF2 XKR8 CYB5R4 MEGF9 STAM2 MARC1 ARPC5	down	*
GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP	0.0009013	0.0117114	0.4772708	-0.2904794	-1.538952	173	LRRC8C MYADM RTN3 INPP5A C8orf58 TSHZ1 PEAR1 TXNIP SLC36A4 TTL CYB5A ANXA5 RB1 MCL1 ZMIZ1 AGO4 AHNAK FOXO1 TCP11L2 PXDC1 SOCS5 KLF7 ADD1 MAPRE2 AFF3 NCOA1 ZDHHC20 HEXB FRY WASF2 C20orf194 RAB31 KCTD12 PTGER4 CD83 GTDC1 SLC25A24 TESK2 SBF2 HBP1 ADAM10 SLC35D2 TXNDC15 ARHGAP18 MEGF9 LYST ANO6 SLC16A10 GJC1 SLC19A2 ING1 SLC38A2 FAM8A1 KBTBD11 TUBA1A ATP1B1 MICAL1 SNX14 MTSS1 GPR137B	down	*
GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_UP	0.0029602	0.0288286	0.4317077	0.3390703	1.538558	176	GGCT AGFG2 ASIC1 AP1S1 TTC26 CDCA8 CENPA TPX2 E2F3 CCNB2 HMMR NLE1 MCM7 RAD54L KIF11 DCTPP1 SYMPK FAHD2A BIRC5 ATIC MRPL17 ARNT2 PIAS3 SNRNP25 MZT2B UQCRFS1 COA3 PUS1 MLF2 PINLYP PKP4 ZNF768 CCDC51 RNF187 PTER TIMM13 STOML2 IARS2 FAM136A BCL2L1 MRPL24 BLCAP PRMT1 NFE2 ESRRA STK39 PYCR1 PPFIA3 CHMP1A RSAD1 EYA4 VDAC3 GGCX SRPRB PPP2R5D TK2 PCTP CYB5B DNAL4 CAMK2N1 ACSBG1 EIF2B1 PRPF19 DSN1 CAMK2G NHP2 MTMR4 PRCC RFX7	up	*
GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP	0.0012011	0.0146625	0.4550599	-0.2898356	-1.538541	178	SMAD6 KRT81 SECISBP2L LPXN LIPA MYADM PAFAH1B2 SEMA6D KLHL30 B3GNT5 AKT3 EPB41L2 KIF1C MPEG1 NOSTRIN CASP1 KLF4 FAM76A MVB12B LAPTM5 NFKB1 CTBS C9orf72 ID2 MBD2 MATN2 PAFAH1B1 PIK3R5 DCHS1 MTPN PKIG RBPJ HESX1 NEK7 RNF141 CRNKL1 PDCD6IP ARL6IP6 SH3BP5 MN1 MSRB3 JUNB GPR183 HIVEP2 STX12 ATAD2B ANKLE2 EGFL7 OPN3 DDX59 SSH2 TMEM109 TLK2 CAMSAP2 NABP1 PURB BANK1 EIF4G2 ACVR1C CHML	down	*
ZHOU_INFLAMMATORY_RESPONSE_FIMA_UP	0.0000066	0.0001946	0.6105269	-0.2661347	-1.538517	382	RTKN2 CXCL3 SEMA6A EREG HSPB7 AKAP5 ARHGAP31 IL1A MS4A7 DENND5A USP12 CD55 KCNA2 ZC3H12C IL1B P2RY1 EMP2 RDX RAPGEF2 MIR22HG CD44 EMCN STXBP6 CCRL2 DDX6 NEDD4L FOSL1 UBE2FP1 CYP4A11 IL23A ZEB2 KCNAB1 TMPRSS6 ATP2B1 CLCF1 SGMS2 ADAM17 PRMT5-AS1 MTF1 BTG2 RNF144B FZD4 LITAF HIPK3 PTX3 EIF4E MOB3C LDHAL6A AGBL1 MAP2K3 STAT5A TBC1D9 SNAI1 PTPN21 LIMS1 PLAUR PXDC1 DRAM1 C1QTNF7 NFKB1 C4orf33 CXCL2 IRAK2 HOPX CCL4 PNRC1 TBX5 MAFF KREMEN1 VWF RASGEF1B AFF3 TGFB2 SNN NINJ1 ZCWPW1 AXDND1 KANK1 CD80 IL6 C9orf131 PIKFYVE SERPINB8 JUN PNMA2 CNTN4 HSPA1B PLK3 EPC1 RHOJ PPP1R15A WTAP ELOVL7 FERMT2 CD83 IRF8 FSD1L REL TNFRSF9	down	***
CEBPA_01	0.0006016	0.0085632	0.4772708	-0.2875128	-1.538332	186	TNR SMAD6 GPATCH11 CD55 SLC16A12 ARRDC4 BDNF HCAR2 RASAL2 AQP9 S1PR1 TRIB1 EIF4A1 MCTP1 CHMP1B GPBP1L1 RBM4 SIRPA ADRB2 LHX6 ZEB1 PDE4D MAP2K3 ID3 ZADH2 CADM1 UBE2E2 GPR85 FCER1G HTRA4 CRIM1 NCKAP5 FOXN3 MYO1C HCAR3 MITF NOTCH1 RHOBTB2 JPH1 FBXO11 SP3 GYPC ITGA11 RHOQ TSC22D1 SKIDA1 SLC24A1 CSDE1 TOB1 TCF7L1 MBNL1 SPIB RASSF8 COL13A1 NRP2 PPP1CB FNBP1 CFL2 CHML ZBTB8OS CLOCK RB1CC1 CD109 KMT2E CTDSPL2 CALR WNT5A NXN ANGPT2	down	**
GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_UP	0.0029602	0.0288286	0.4317077	0.3389924	1.538204	176	SPATA24 C1GALT1 NUP107 SLFN13 DNAJC12 MND1 KIF18B THOC3 NDC80 PIF1 SORD BAIAP2L1 NUF2 CDCA8 ESPL1 TFDP2 CCNF SMARCC1 KIF23 KCNN4 MKI67 WDR78 KLHDC4 KIF11 GPSM2 PFN2 CKAP2L XRCC1 SPC24 IDH2 RASSF6 CMAS CTDSP2 CDK1 NCAPG ANAPC7 PLCG1 RTCB NADK2 DHX40 MBD4 TRIM37 LRWD1 SLX4 CDC7 SASS6 BRD8 MAN2A1	up	*
GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_UP	0.0011174	0.0138582	0.4550599	-0.2936041	-1.538123	157	EREG PRX NEDD4L STX11 OTUD4 MCTP1 MASP1 TNIP3 MAP3K8 RNF144B IL18R1 MAP2K3 CSRNP1 STAT5A BIRC2 SORBS1 CCL4 PLEK IL7R PIK3R5 SNN TDRD7 NINJ1 DDX60L IL6 OASL NXF1 MAP4K4 PLK3 PPP1R15A WTAP SKIL CD83 PI4K2B GPR183 PTGER2 PELI1 FXYD6 EHD1 SERPINB1 DUSP5 ARAP2 ANKLE2 C3orf38 IL18RAP MIR155HG EGFL7 RIPK2 ADORA2A AIM2 EHD4 PIM3 RBMXL1 SERPINE1	down	*
PRC2_EZH2_UP.V1_UP	0.0019533	0.0210552	0.4317077	-0.2991511	-1.537950	147	SLPI EREG TMEM100 KLF13 KCNA2 PRKG2 PTPRB BMP2 AATK FLVCR2 CDH13 MTMR10 IL1RL1 TRIB1 MCTP1 HBEGF ANPEP MALL RGCC PDGFA CDADC1 DUSP3 KIAA0513 KLF4 NES PAQR5 KLF11 RASL12 SLC14A1 KCTD12 OSTM1 DUSP8 IRF8 IDS GFPT2 PKIA FXYD6 OSGIN1 ATXN1 CCDC68 KYNU CLEC2B SLC35D2 OPN3 PAMR1 TTLL7 MEGF9 EDN1 COL13A1 NR3C2 CD70 CLIP1 NR4A2 CLEC4E SLC19A2 EYA3 YRDC OTUB2 FPR3	down	*
GSE3982_MAST_CELL_VS_BASOPHIL_DN	0.0009478	0.0121914	0.4772708	-0.2922692	-1.537858	168	EPAS1 ABHD5 ARHGEF15 MYD88 YPEL5 GIMAP6 PILRA DNAJC3 SPTBN1 ZFYVE16 TCAP PDE4D MAP1LC3B DENND3 PTPRC DUSP11 DUSP1 ALOX5AP CCDC59 RPF1 N4BP2L1 PPP2R5A LMBRD1 HSDL2 ARHGDIB ZCWPW1 WASF2 BCAR3 UTRN NECAP1 CD48 RAB31 JAK1 RASSF2 DYM UBB PELI1 VAMP4 TMEM230 HBP1 EXOC1 MACF1 ETS2 ARAP2 SELPLG CCDC69 ACTB MARC1 RNF38 FOXJ2 DAZAP2 CCND3 PMAIP1 CSF2 HTRA2 CDC14A TMEM50A ZNF106 CX3CR1 OSGIN2 RB1CC1	down	*
GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN	0.0006927	0.0095534	0.4772708	-0.2889484	-1.537826	177	SIDT2 DENND5A KLF13 CALCRL MKNK1 NR3C1 GIMAP6 CBL FAM49A NUMB ANXA1 UBL3 CHMP1B EIF1 RAB33B RNF125 GLS HNRNPDL IL10 MAFG FAM49B NFKB1 RBMS1 CLK4 PAFAH1B1 AFF1 CRIM1 CDKN2AIP TAF13 FOXN3 VAMP3 VPS37A SAR1A PIKFYVE NXF1 NECAP1 SF3B1 KCTD12 N4BP3 REL NDST1 AZI2 TFEB CDC37L1 VPS39 PCM1 SF1 SFT2D1 IQSEC1 FBXO30 CREBBP SSH2 NHLRC3 SKI TTC19 FAM13B NIPSNAP3A CDKN1B DUSP6 ENDOD1 CDC42BPB ATP1B1 RNF167 SRSF11	down	**
GSE42724_NAIVE_VS_B1_BCELL_DN	0.0014389	0.0166977	0.4550599	0.3403378	1.537799	172	GGCT GPR35 MRPS35 DCTN2 NEURL2 SPDYE1 EEF1E1 POLD2 PRKDC FBL DCTPP1 TIMM50 LRRC45 PES1 TMED3 MRPL36 MEA1 EXOSC2 MRPS2 ZNF584 NRGN OVOL3 ATP6V0E2 LMNB2 MRPS34 ARL6IP4 DPH2 S100A9 MRPL4 ANAPC1 SND1 MRPL24 PRMT1 TMEM147 RABEPK EIF3K ALG8 JAKMIP3 TMEM117 DOCK3 GTF3C2 SNRPD2 CCDC167 HLCS COX5B SLC25A29 PFKM RHOT2 AURKAIP1 TIMM44 APEX1 MRPS27 PTOV1 NUP210 MRPL48 TMEM161A TPM1 EIF2D PPARGC1B MRPL12	up	*
GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP	0.0032692	0.0311744	0.4317077	0.3443220	1.537755	153	MUC4 PBK BRCA1 DIO2 CCNF GOLPH3L SOX30 TP53BP1 KNTC1 EXOC4 TMEM184A KIF2C POC1A CDCA5 HOXC6 WNT1 CHAD FAM162A NUDT17 B3GNT3 TIMM50 SPATA17 GEMIN7 PML NAA40 SPACA4 VANGL2 OARD1 LRRC56 DIAPH3 PYROXD2 MYO19 C19orf18 CCNE1 SCLY NMRAL1 TJAP1 SGSM3 ANAPC1 TRAF3IP1 CLTB SULT1B1 SASS6 KRT8 KDM4B GID8 USP21 LANCL2 C1orf109 VWA3A PRR11 STAB1 CARHSP1 LLGL1 MXD3 ESPN SIAE ARHGEF10L C4orf46 LUC7L3 CRYGS SH3RF2 PCNT CYP8B1 XAF1 DHX32 AP1B1 GCNT1 GOLT1A CMPK2	up	*
GSE360_L_DONOVANI_VS_T_GONDII_DC_DN	0.0027662	0.0273050	0.4317077	0.3440994	1.537616	154	KIF1A ALDH3B2 FOXM1 HABP2 RUVBL1 AP3B2 BUB1B PROM1 IGF2BP3 IQCE EIF2B5 NDUFS6 SIX1 CCL8 ACOT8 ALDOC NME1 CYP24A1 AURKA POLA2 IGLV1-44 WIPI2 PDZK1IP1 MAD2L1 FBL XRCC1 CDK1 IGSF3 CCNE1 MTOR MLF2 LMTK2 MARCKSL1 RPA1 MCM6 PRMT1 MCM5 CHRNA5 MSH2 MMP16 NME4 ANK2 GNE TBL3 NELFA VNN1 SARDH BEAN1 IFI44 GSTP1 CADPS NHP2 MTMR4 MTR DYNLT1 CALM3 IGF1R STMN1 IGLV3-25 ACTN4 TNFSF4	up	*
GO_RESPONSE_TO_BACTERIUM	0.0000026	0.0000880	0.6272567	-0.2622487	-1.537468	447	SMAD6 SIGLEC11 CXCL3 NLRC4 SLPI ACP5 KMO IL1A SASH1 EDNRB SCIMP SIGLEC16 CD55 SPN PGC IL1B FABP4 THBD BMP2 LPL LY86 CAV1 BAIAP2 MYD88 CHIT1 TBXA2R C5AR1 FGF10 IL1RN SLC11A1 PPM1D TRIB1 IL23A FGR CASP9 RHOA CD36 MIR146A CARD16 ADAM17 TNIP3 LITAF FOXP1 MS4A1 SERPINB9 SIRPA TRAF6 GRN PDE4D RAB14 GPM6A IL10 PTGIR MPEG1 CASP1 PTAFR ADAMTS9 LY96 CCL3 NFKB1 CXCL2 IRAK2 VIM SELP AXL TLR4 SFTPD FCER1G C4BPB IL24 ANXA3 GNRH1 HCK SNX3 RBPJ CD80 IL6 CD160 JUN NOTCH1 CARD8 JUNB PTGER4 CCR7 IRF8 PRKCE PTGER2 MALT1 UNC13B CXCL5 IGKV3-20 PLCG2 FOS PELI1 MAPK8 CCR4 IRF5 TGFB1 AKIRIN2 CD1D CD6 FPR2 NLRP6 IFNAR1 CD86 PLSCR4 KLRC4-KLRK1 IGHV3-23 PLAA PDE4B MR1 TSPO CCL20 SYT11 JUND ICAM1 IL18 VGF TFPI SCN7A TAB2 RIPK2 NLRP3 HAVCR2 MT1M EPHA2	down	***
GO_GAMETE_GENERATION	0.0000434	0.0009598	0.5573322	0.3127775	1.537219	443	TSPAN8 TRIP13 TP63 SPATA24 SPATA25 MYCBPAP FOXA3 RUVBL1 PMFBP1 CCNB1 WFDC2 DPY19L2P1 GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 SPINK1 CIB1 TDRKH MCM8 SRPK1 RSPH1 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A AURKA REC8 ODF2 SYCP2 POC1A DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 OAZ3 CGB7 HSF2BP BRIP1 SPAG8 PTGDR2 CCDC136 MEA1 ASF1B LRGUK MERTK PICK1 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 MTOR CTSV MNS1 ADAM28 IQCG MORN2 PCSK4 GAS2 TSSK3 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 TYRO3 NR6A1 KDM3A PTN MEI1 ROPN1B BCL2L1 CATSPER2 BAD DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 GGT5 ETV6 PHC2 PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2	up	***
GO_ORGANELLE_ASSEMBLY	0.0000011	0.0000412	0.6435518	0.3048070	1.536957	679	CCNO PKHD1 MCIDAS ONECUT2 ONECUT1 CEP72 SPICE1 MDM1 CEP89 RPGRIP1L CHEK2 NEK2 CENPF AVIL NUDCD3 RAB3IP MKS1 CCDC113 BRCA1 SIX4 STK36 RACGAP1 IFT122 SPAG17 ANLN SNF8 ASPM STIL MSTO1 TTC26 CEP70 PLK1 IFT27 AURKB CENPA TPX2 MYBL2 GRB7 PLS1 PIP4K2C KIF27 DCTN2 WDR90 DNAI1 HAUS5 CEP250 WDR62 RSPH1 ARMC4 TNNT2 NLE1 KIF23 BBS1 SPAG16 BICD1 FOXJ1 KIF3B CCDC13 FBF1 MAP10 AURKA ODF2 SFI1 IFT43 TPR CENPW POC1A HYDIN MAP1LC3C WIPI2 TEKT2 ERAL1 CCDC114 DCDC2 FHOD3 KIF11 GPSM2 WDR60 NME5 DNAH8 IFT172 NEB GAS8 KIF3C CBY1 DNAAF3 MRPS11 RABEP2 CCDC136 C2CD3 CCDC40 CCDC78 HPS4 DRC1 LRGUK LRRC6 IQCB1 CDK1 CROCC CEP97 CENPJ CENPH BIRC5 KIAA0753 STX18 VANGL2 VPS28 MRPS2 TCTN2 KIF2A RUFY4 SSX2IP DYNLL2 SPAG5 POC1B TRAPPC12 DNAH5 PRKAA2 NOP2 TMEM231 FGFR1OP IFT52 KPNB1 EIF6 ULK1 CEP63 BBS5 CEP192 NPHP1 TUBG1 DNAH7 CNOT2 NINL MNS1 CCDC151 MRPL11 IQCG TRIM37 TMEM237 ATG9B VIL1 SPAG1 TEKT3 SMIM22 KRT19 TRAF3IP1 DNAJB13 CENPK PROX1 SASS6 CKAP5 VPS25 CDC20 IQUB WDR34 NPRL3 AAAS TTLL3 TCTN1 NRXN2 CHMP4C CDK5RAP2 KRT8 ODF2L CENPT DNAI2 WDR35 ANKRD1 HAUS6 DYNC2H1 FAM161A TBC1D30 RCC1 WDR45B HAUS4 LSM4 MYH3 RSPH4A SH3PXD2B TCHP UNC119B CEP152 RAB34 NUP62 TMEM17 B9D1 ALMS1 DBNL TUBGCP4 ICK CEP164 CLUAP1 DNAH1 CHMP1A MARK4 NLGN2 CHMP2A CELSR2 TBC1D32 TTC39C ATG2A VDAC3 CENPE MAP1LC3A UBXN10 LRSAM1 CELSR3 GOLGA2 HGS SYNE2 TTC30B CAPN9 MRPL20 ZMYND10 MAP9 RRS1 WIPI1 NLGN1 CLASP1 KIF24 BRIX1 TRAPPC6A POGZ KIAA0586 TPM1 CEP290 CHMP6 RPL23A ARMC2 MRTO4 DNAAF1 DRG1 DYNC1H1 MAK TEKT1 ABLIM3 WRAP73 WDR63 ARHGEF5 PLK4	up	***
GO_FAT_CELL_DIFFERENTIATION	0.0014624	0.0168854	0.4550599	-0.2895438	-1.536850	180	FFAR4 SMAD6 OSBPL11 PPARG GATA2 LRRC8C FABP4 BMP2 INSIG1 LPL EGR2 FGF10 MIR27B ADRB1 GATA3 NR4A1 ADRB2 SFRP1 WNT3A HNRNPU TCF7L2 PRDM16 FOXO1 KLF4 RUNX1T1 ZADH2 ARNTL CEBPA GRK5 PER2 ID2 ARL4A HES1 MEDAG PIAS1 ID4 IL6 EBF2 CCDC3	down	*
MODULE_105	0.0026866	0.0267233	0.4317077	0.3365007	1.536697	184	SAA1 FOXM1 LAD1 NEK2 CCNB1 IGF2BP3 CENPA UMPS MYBL2 CCNF GPX2 MELK CHAF1A MKI67 KNTC1 PAFAH1B3 TPBG POLD2 MAD1L1 COASY RRM2 AIMP2 SOX4 EMG1 RBP1 TOPBP1 MAD2L1 PFKP BLM PHB CKS1B SUPT5H CDK1 BIRC5 ARPC1A GOT2 COL3A1 CDH3 EZH2 FADD DAP ITPR3 TUBG1 CCL21 COG2 COL5A2 DTYMK MGMT ASNS S100A13 FXYD3 LTBR P4HA1 RPA1 POLR2J COMP CACNB3 PFKFB4 CBR1 MSH2 CCNA2 FAM3C	up	*
GSE18893_TCONV_VS_TREG_2H_CULTURE_DN	0.0009013	0.0117114	0.4772708	-0.2892746	-1.536601	179	LPIN2 ADPRH ARRDC4 SUSD2 GPCPD1 INPP5A AGPAT4 TGFBR2 SERPINB9 NFE2L2 CRK RAB14 IL10 NRARP RAB12 ITPK1 MGAT4A CDKN1A VIM CTBS ID2 PIK3C2A ARL4A RAP1GDS1 WFS1 MARK3 MYO1C VAMP3 SGK1 SOCS3 SNX2 CCR7 TBX21 CGGBP1 SNX9 RRAS PNPLA2 RUNX3 DAGLA STXBP3 EHD1 FEM1B CYGB STX12 GPR18 KAT2B ICAM1 ARAP2 G3BP2 CTSC NABP1 CYBA CRTAP CFL2 SLC19A2 DCUN1D3 SH3GLB1 NCF1 PLEKHA2 PCMT1 MAN1A1 IRF1 FNDC3A RAB1A	down	*
CREBP1_Q2	0.0003917	0.0060789	0.4984931	-0.2820060	-1.536435	207	SLC6A4 FAM167A ZMYND15 KLF13 HHEX RBMS2 SIK1 EGR2 AGPAT4 TRIB1 ZBTB21 PPP2R2A SPI1 PDE4D DIABLO TAPT1 DAAM2 PEG3 ID3 USP2 DPH3 SIK2 PNRC1 CCND2 PER1 DUSP1 WDR48 PAFAH1B1 CALM2 MAFF AKIRIN1 RAB6A KCNA5 GPBP1 SLC25A25 FLT1 CREM DNAJC27 OXNAD1 OSBPL9 RCAN1 PPP1R15A CDK2AP2 LETM2 MCAM FOS GPR3 FOSB ING3 PNPLA3 HNRNPA2B1 ZBTB11 ATP6V0C CSDE1 PPIG LTBP1 MBNL1 GEM SLC31A1 VGF OSR1 EPHA2 RET THRAP3 DLST GPR171	down	**
GO_POSITIVE_REGULATION_OF_CELL_CELL_ADHESION	0.0003155	0.0050878	0.4984931	-0.2823350	-1.536371	220	SIRPB1 CD55 IL1B FYN CD44 CAV1 CITED2 CDC42 TGFBR2 IL23A RHOA ANXA1 CD5 ADA FOXA2 MAP3K8 HLX GATA3 SIRPA TRAF6 WNT3A TFRC NODAL ZMIZ1 IL10 DENND6A PTAFR CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SMAD7 IL7R HES1 NCKAP1L CD80 IL6 CD160 ETS1 PODXL CCR7 PIK3R1 CD83 GRB2 MALT1 DOCK8 AP3B1 FSTL3 RUNX3 CD74 CD1D ZBTB1 CD6 CD86 PDCD1 CD81 KLRC4-KLRK1 ICAM1 IL18 RIPK2 NLRP3 HAVCR2 PAK2 KLRK1 TNFSF9 PIEZO1 CD70 ZBTB16 ICOS HAS2 EFNB2 WNT5A BCL10 HMGB1 CD3E TNFRSF13C ITGA6 PDPN NR4A3 CD4 NFKBIZ EBI3 CBFB PNP ADAM19 PYCARD	down	**
ATGCAGT_MIR217	0.0053484	0.0449762	0.4070179	-0.3189684	-1.535750	92	KCTD9 VAT1L ZCCHC2 DYRK1A PPM1D UBL3 TACC1 PAQR3 DACH1 NDEL1 MAPK8IP1 GPM6A CUL5 MTPN RBM39 FBXO11 RIN2 HNRNPA2B1 PDS5B ATP6V1A PCDH17 KCNA3 YAF2 SLC31A1 TLK2 EIF4A2 SPOPL MIER3 YTHDC1 NR4A2 MAPK1 MAMDC2 SLC38A2 KIAA2026 ATP1B1 ESCO1 TAF1D SIRT1	down	*
LIU_PROSTATE_CANCER_DN	0.0000026	0.0000870	0.6272567	-0.2646089	-1.535749	415	RBP4 EPAS1 TMEM100 SOSTDC1 FOXF1 SLC47A1 FGD5 WFDC1 ADCY9 ADCY4 CYP4B1 FYN TXNL1 CAV1 CORO1C TGFBR3 GAS6 EOGT EPB41L3 HSPG2 SEMA6D STARD4 TACC1 WNT2B RAP1A CSRP1 MASP1 ECHDC1 HSPB1 PRELP CAV2 DES STOM GATA3 TNS1 KANK2 BTG3 TUBB6 PPP3CC CFD PER3 KCNMA1 SORBS1 BNIP2 CASP1 AOC3 KLF11 GRK5 CLIC4 MYO15B ITIH5 MARVELD1 RBMS1 CCND2 DSE WFS1 ACTG2 CLIP4 SLC6A6 VAMP5 PRICKLE2 MYH11 CRIM1 MRVI1 RASL12 CNRIP1 TGFB2 PDK4 TSPAN18 ID4 CPAMD8 SYNPO2 PODN AQP3 LAMB2 NDNF C20orf194 SLC14A1 MSRB3 CCDC50 DUOX1 RHOJ FERMT2 PIK3R1 ACKR3 GYPC PTGER2 PREX2 MCAM EHD2 PKD2 FLNC MME FXYD6 TIMP2 VAV3 ITGA9 TGFB1I1 PDLIM1 MEIS1 MYOCD MRGPRF SBSPON RIMKLB LTBP1 MR1 TAGLN ETS2 LMOD1 CDC42EP3 ALDH2 TBC1D1 ACACB GPD1L EPHA2 SCPEP1 S100A4 METTL7A TTC28 KIT TIMP3 PDE4A MAGI2-AS3 LYST FGFR1 COL13A1 NR3C2	down	***
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_DN	0.0010299	0.0129999	0.4550599	-0.2948677	-1.535310	161	ABHD5 ASGR1 MIR22HG HSD17B6 SLC6A12 EGR2 BACH1 EML1 BCL2A1 NCF2 IL1RN FAM49A SYNC SIGLEC6 LRRFIP2 ADIPOR1 RGCC ATP6V1H ATP6V1B2 KIAA0513 PTAFR CLIC4 SPAG9 ATF3 CDS2 B9D2 DCHS1 CLN8 RPS6KA2 PGD ETV3 SH3BP5 KLHL18 PSTPIP2 HOMER1 RNF24 RALB TAGLN2 TIMP2 SAV1 TGIF1 TSC22D1 CD86 KYNU VPS39 ELOVL1 IQSEC1 ALDH2 GLRX2 CAMSAP2 DOCK4 NRG1 GREM1 C5AR2 DUSP6 EXPH5 TMEM43	down	*
REACTOME_INNATE_IMMUNE_SYSTEM	0.0000000	0.0000006	0.7477397	-0.2440756	-1.535235	857	POLR3H SIRPB1 NLRC4 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 FCN3 IL1B MNDA LTA4H CAT RAB44 CLEC12A LRRFIP1 PTPRB OSCAR FYN CD44 LY86 FCER1A BAIAP2 MYD88 CHIT1 CYB5R3 CD300E IGKV1-33 PAFAH1B2 C5AR1 CLEC10A YPEL5 MEF2A ELMO1 CDC42 MANBA NCF2 VAPA FUCA1 PSMD5 LAMP1 SLC11A1 NFATC3 LILRB3 FGR CASP9 RHOA TXNIP CD36 SLC44A2 DNAJC3 MAN2B1 IGKV2-28 CD33 ARSB ASAH1 RAP1A RASGRP4 GM2A CLEC7A MASP1 MAP3K8 RNF125 ANPEP PTX3 STOM LAIR1 PPP3CA SIRPA TRAF6 CD93 GRN LAMTOR3 CRK UBE2D3 TXN ATP6V1H RAB14 ATP6V1B2 CD58 CST3 MAP2K3 FABP5 CFD DUSP3 CCL22 BIRC2 SDCBP MEFV CASP1 BST1 PTAFR PLAUR ROCK1 GAA OSTF1 ATP6V1D LY96 CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX NKIRAS1 PTPRC IRAK2 SELL HPSE ATP6V0D2 TLR4 ARHGAP9 ACTR3 SFTPD CD53 CAPZA2 FCER1G WASF3 GCA KLRD1 C4BPB DEGS1 CD300LB CMTM6 ACTR2 GLB1 HEXB HCK HGSNAT RAB6A NCKAP1L RPS6KA2 PRCP IGLV2-11 MYO1C PPP2CA WASF2 MUC3A CTSS PSEN1 SNAP23 C1QA JUN PSMA1 VAT1 RAB31 HK3 CTSZ RAC2 ATP6V0B TYROBP TREM1 HSPA1B ATP11A RHOG ENPP4 EEA1 GLIPR1 PIK3R1 GMFG PRKCE GRB2 CREB1 MALT1 SIGLEC15 SERPINB6 RPS6KA1 CAP1 PRKACA IGKV3-20 PLCG2 FOS ATP6V0D1 UBB PELI1 CALM1 PSMD12 ICAM2 ALDH3B1 MAPK8 TREX1 KLRC2 BIN2 CR1 MME PPP2CB TIMP2 SIGLEC14 VAV3 DOK3 SERPINB1 TEC FPR2 ATP6V1A TSPAN14 PIK3C3 DYNC1LI1 ATP6V0C GPR84 PPP3R1 CD81 LGALS3 IGHV3-23 ORM2 BRI3 PLEKHO2 ADAM10 IST1 IGKV1D-39 COMMD9 UNC13D CCR6 LAT ARPC2 HSP90AA1 TAB2 RIPK2 NLRP3 HSPA8 UBE2D1 ACTB PSME4 CREBBP METTL7A ICAM3 CD19 TLR10 NHLRC3 NFKBIA SIGLEC9 CTSC CD3G ARPC5 PAK2 KLRK1 DUSP7 SNAP29 AIM2 P2RX1 ITCH PSMD6 IQGAP1 CREG1 PSMD9 CNN2 ANO6 LYZ MS4A2 ABI1 UBE2V1 CYBA ATP6V0A1 SUGT1 IGKV2-30 C5AR2 C1QB CTSH DUSP6 TMEM30A ATP11B ATF2 CLEC4E C5 MAPK1 ITGAL TREM2 FTL NCF1 S100A8 RAB37	down	***
KEGG_WNT_SIGNALING_PATHWAY	0.0009865	0.0125820	0.4550599	-0.3042245	-1.535212	135	SFRP4 WNT4 SOX17 FOSL1 FRAT1 NFATC3 RHOA WNT2B NLK FZD4 PPP3CA SFRP1 WNT3A TCF7L2 PPP3CC ROCK2 DAAM2 ROCK1 CXXC4 CCND2 PPP2R5C PPP2R5A PRICKLE2 SIAH1 WNT9A PPP2CA PSEN1 NKD2 JUN RAC2 PRKACA CACYBP PRKCG MAPK8 WNT11 PPP2CB PPP3R1 CSNK2A2 TCF7L1 SMAD2	down	*
GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN	0.0034094	0.0322721	0.4317077	0.3377475	1.535082	178	DDX11 MDM1 RUVBL1 BUB1B FLAD1 PLK1 ALDH18A1 KNOP1 PRC1 PIP4K2C RANBP1 NDUFB8 ZNF443 TRMT61B DSCC1 SNAPC4 PPP5C HPS4 HARS2 ZNF45 ING4 BIRC5 ATIC GMNN POLR3K LARP1 FEN1 SSX2IP MRPS12 PLCG1 GOLGA5 RNASEH2A FAM86C1 MPI SNRNP25 ZGPAT UQCRFS1 TUBG1 VPS41 FMO6P GINS2 MRPL4 KDM3B PTER CENPM YLPM1 RPA1 BAD BLCAP RABEPK LSM4 TXNL4A WDYHV1 UNC119B	up	*
GSE17721_0.5H_VS_4H_POLYIC_BMDC_UP	0.0017893	0.0196518	0.4550599	0.3401174	1.535029	166	PTPRZ1 TP63 FOXM1 SPICE1 BDH1 EPN3 ELOVL6 CREB3L4 CDK4 INTS1 TOP3B CEP250 SAE1 MCM7 MAD1L1 GPR146 MCM3 CCDC58 FAM162A KDELR2 GET4 CC2D1A FBL MSI1 TIMM50 SAMD10 PPP1R37 MEA1 TAF6 LZTR1 POLR2H DPH2 PCSK4 SLC26A1 GTF3C1 CPSF4 ORMDL2 BCL2L1 MADCAM1 CYP4F12 HAUS4 ERGIC3 CORO2A CEP85 LHX4 GTF3C2 TRIP4 ENPP5 EARS2 GPX7 CDKAL1 NPR2 MRPL48 NCAPH BMF SPHK2 PNPO LCMT1 NHP2 SHMT1 ZNF790 SPRYD4 SRSF9 HAAO TPH1 PPP4C C15orf40	up	*
GO_MICROTUBULE_BASED_TRANSPORT	0.0030035	0.0291950	0.4317077	0.3410167	1.534640	163	KIF1A KLC3 AP3B2 UCHL1 STK36 IFT122 SPAG17 TTC26 IFT27 DYNC1I1 KIF27 KIF23 BICD1 COPG2 COPG1 KIF3B IFT43 DPCD BLOC1S1 WDR60 NME5 IFT172 GAS8 KIF3C DNAH11 CCDC40 KIAA0556 LRRC6 KIF5A AP3D1 SUN1 SSX2IP DYNLL2 LCA5 DNAH5 IFT52 SPG7 SPA17 TRAF3IP1 WDR34 AP3M2 WDR35 DYNC2H1 NEFH SYBU ICK CLUAP1 DNAH1 TRAK1 RHOT2 MAPK8IP3 CAMSAP3 DTNBP1 SYNE2 TTC30B RASGRP1 TMEM201 DNAAF1 DYNC1H1 MAK ROPN1L OPA1 KIFAP3	up	*
GO_POLYMERIC_CYTOSKELETAL_FIBER	0.0000310	0.0007236	0.5573322	0.3097097	1.534397	509	KIF1A SAA1 KIF12 KLC3 KIF20A MDM1 KRT5 PKP2 DNAH2 RPGRIP1L NEK2 KIF18B PKP1 TUBB2B RACGAP1 GTSE1 KIF14 SPAG17 ASPM PLK1 KRT16 AURKB TPX2 DNAH3 PRC1 PLS1 DYNC1I1 CCT6A KIF27 CDK5RAP3 KRT15 DNAH14 CCT2 DCTN2 NME1 MICALL2 DNAI1 HAUS5 RSPH1 TTLL4 DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 KNTC1 KIF3B FBF1 MAP10 CCT5 GPER1 AURKA ODF2 FLG KIF2C CD2AP MAP1LC3C TEKT2 FSD1 HOOK1 DCDC2 KIF11 LMNB1 DNAH8 GAS8 KIF3C DNAH11 TRPV4 MYO1A PSRC1 INCENP KNSTRN NUSAP1 PAK1 KRT18 CDK1 DNAH6 KIF5A CENPJ BIRC5 CCT3 TTLL9 JAKMIP1 SCTR KIF19 SPAG6 KIF2A NARF KIF7 DYNLL2 SPAG5 DNAH5 KLHL22 EIF6 UPP2 TUBG1 DNAH7 DNAJA3 NINL LMNB2 MNS1 TUBB2A TUBA3D KIF22 DNM1 DBN1 TUBA8 KIF21A GAS2 HID1 MAP6D1 KIF20B SMTNL1 KRT19 TWF1 POLB CCT7 KLC2 KLC4 CKAP5 TUBG2 TTLL3 CDK5RAP2 KRT8 DYNC1LI2 KIF21B EML6 TBCA CKAP2 DNAI2 KPTN HAUS6 DYNC2H1 FAM161A RAB3D KATNB1 SKAP1 TTLL6 HAUS4 NEFH TCHP KRTAP5-9 MICAL3 APC2 DBNL NAV1 TUBGCP4 SYBU ACKR2 CCDC181 DNAH1 HOOK2 TUBA4B TPGS2 CDK5 CTTN TBCB BCAS3 CAMSAP3 CENPE MAP1LC3A SRPRB GOLGA2 ESPN TTC30B DCDC1 PNN KRT80 TUBA1C KRT17 MAP9 BFSP2 DNM1L TTLL5 CLASP1 KIF24 MAP2K2 CORO1B ROR2 TPM1 DNAL4 SHROOM1 VPS18 DYNC1H1 TEKT1 BAG2 GSK3A RUSC1 FAM110C PCNT TUBGCP2 KIFAP3 LZTS2 PARP4 RCC2 NCKIPSD TPPP3 NDRG1 TMEM214 KIF6 WIPF3 RAC3 KEAP1 TPPP LRPPRC FMN1 REEP4 DYNLT1 CALM3 DNAH9 DPYSL3 DSP TUBGCP5 DLGAP2 KIF3A PAWR	up	***
REACTOME_RESPONSE_TO_ELEVATED_PLATELET_CYTOSOLIC_CA2	0.0027504	0.0271890	0.4317077	-0.3070653	-1.534388	107	PECAM1 CLEC3B MMRN1 CTSW CD9 GAS6 CD36 ANXA5 SRGN PDGFA CFD THBS1 FAM49B ABCC4 SELP PLEK VWF TGFB2 PHACTR2 CYB5R1 CAP1 TAGLN2 CALM1 PRKCG STXBP3 TGFB1 TMX3 CDC37L1 APLP2 ORM2 ACTN2	down	*
GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN	0.0005945	0.0084838	0.4772708	-0.2884540	-1.533857	176	WEE1 SLC31A2 FCN1 CD55 CAT LMO2 RTN3 ANXA1 ASAP1 CYB5A SLC25A37 CLK1 CFD DENND3 CLIC4 SCAF4 SIK2 HOPX HPSE MBD2 PPP2R5A BCLAF1 RAB6A SACM1L EMP3 SERTAD2 TMEM251 IRF8 DDX5 REL UVRAG KLF2 AZI2 PKD2 PPP2CB CHPT1 GSAP SERPINB1 BAZ2B GALC LGALS3 THAP11 USPL1 ALDH2 SCPEP1 NFU1 RHOT1 CSF2RB HMGCS1 SSB CLOCK CMPK1 ANKS1A SNW1 HLA-DRB1 WAC DAPP1 WDR47 TSC22D2 TES SLC23A2 ECHDC3 RAB11FIP2 SECISBP2	down	**
TARTE_PLASMA_CELL_VS_PLASMABLAST_DN	0.0004644	0.0069337	0.4984931	0.3233658	1.533324	275	TRIP13 FOXM1 TROAP NEK2 CCNB1 TTK GINS1 KIF14 STIL CENPA GPI ESPL1 CDC6 NNT TYMS GLDC ORC1 CCNF CCT6A LILRB4 CCT2 NME1 LDHB HMMR KIF23 CHAF1A MKI67 TOP2A CCT5 CBX3 POLD2 KIF2C COASY RRM2 PRKDC MRPL3 KIF11 MCM3 LMNB1 AIMP2 ANG TOPBP1 MAD2L1 AHCY PSMD4 PFKP PHB IDH2 CASP6 CKS1B CBX5 CDK1 EXOSC2 UCK2 ATIC OAT TRAP1 KIF2A EZH2 DNAJC7 VBP1 CCNE1 TUBG1 DLGAP5 PSMA5 PSME2 KIF22 DTYMK GALNT3 ASNS CCT7 KLHDC3 BRD8 CDC20	up	**
GO_MOLECULAR_TRANSDUCER_ACTIVITY	0.0000001	0.0000036	0.7049757	-0.2461729	-1.533166	732	FFAR4 SMAD6 HCRTR1 CLEC1B GPR17 RAMP3 ACVRL1 IL17RB SOSTDC1 FCN1 TEK GPR15 EDNRB PPARG ROBO4 SPN TIE1 F2RL3 LHCGR P2RY1 LYVE1 GPR65 PTPRE RAMP2 THBD PTPRB ENG OSCAR FOLR1 CD44 HCAR2 CCRL2 INPP5K CALCRL CRY2 ADRA1D BMPR2 ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 MARCO NR3C1 TGFBR3 IL1RL1 TGFBR2 SCARF1 IGSF6 PEAR1 LILRB3 CD8A CD36 PKHD1L1 TNFRSF8 SSTR1 PTPRM LTBP4 CD5 CD33 LIFR CHRNE PLXNA2 CLEC7A FZD4 NMUR1 ANPEP PAQR3 ADIPOR1 ADRB1 NR4A1 PLXNA4 TMEM123 ADRB2 IL18R1 CD93 GPBAR1 GPR4 TAPT1 PTGIR EPOR PTPRO CLEC1A GPA33 TACR2 PTAFR PLAUR PAQR5 MPL NPR3 LY96 P2RY2 ITGAX NR1D2 PTPRC GPR85 AXL TLR4 CD302 RECK M6PR PTGER3 FCER1G RNF139 CD300C SMAD7 EVI2A ADIPOR2 KLRD1 CUL5 UNC5A GPR157 IL7R HLA-DQA1 CRIM1 PTH1R PROCR CD8B TRGC2 S1PR4 HCAR3 CD80 FLT1 GPR61 CD160 KLRB1 IL2RB TAS1R1 CD48 NOTCH1 HRH1 ADRA1A TREM1 IFNGR1 GPR141 PTGER4 CCR7 ACKR3 GPR183 PTGER2 NPR1 RTN4R GRIA1 SUCNR1 CD7 TNFRSF9 OGFRL1 TNFRSF10B GPRC5A ITGA11 TPRA1 GRIK1 FGFR4 GPR37L1 GPR3 CD74 KLRC2 CR1 CCR4 EPHA3 SORT1 NR2C1 JMJD6 GLRA3 FPR2 NLRP6 IFNAR1 CD86 CNTNAP1 GPR84 GLRA1 KLRC4-KLRK1 MRGPRF CCR1 CRY1 OR52B6 GPR18 LTBP1 MR1 TSPO IFNLR1 RXRA SMAD2 CCR6 NR2E3 ICAM1 INTS6 IL18RAP OPN3 HTR6 SEC63 CXCR4 EPHA4 CCR9 PTCH1 BCAM EPHA2 GRIN3A TLR10 RET ADORA2A KIT CD3G KLRK1 MMD GPR171 P2RX1 OR1K1 FGFR1 RORA NRP2 NR3C2 LPAR6 SMAD4 FLT4 TNFRSF10D FCRL1 SPHK1 KLRF1 ACVR1C CSF2RB C5AR2 GHR CTSH CDKN1B CNR2 NR4A2 CX3CR1 CLEC4E ITGAL ITGB1 TREM2 GPR153	down	***
ENK_UV_RESPONSE_EPIDERMIS_DN	0.0000061	0.0001839	0.6105269	-0.2575582	-1.532857	461	CLIC3 CD55 WNT4 EMP2 CYP4B1 LRRFIP1 THBD FYN MED4 CORO1C RTN3 FOSL1 EML1 INPP5A MSRA STX11 TGFBR3 GAS6 NFATC3 TRIB1 ARHGAP29 ANXA1 ATP2B1 UBL3 ASAH1 PLXNA2 C1orf21 MAP3K8 HSPB1 PBX3 PPP2R2A GATA3 PPP3CA TRAF6 NDEL1 SPRY2 TFRC RHOB GMEB1 MAP2K3 CFD PER3 CCL22 PTPN21 SAP30BP PLAUR ID3 KLF11 STK17B ARNTL BCHE ABCC4 SPAG9 CADM1 CXCL2 ATF3 PNRC1 DNTTIP2 SMAD7 MATN2 OXSR1 SMNDC1 TP53BP2 NCOA1 FOXN3 RPS6KA2 PKIG FRY TECR DCP1A SCEL ID4 PPP2CA AREG RYBP PNO1 UTRN AQP3 HECA DNASE2 DUSP8 RCAN1 PTGER4 CD83 IRF8 HERC1 GPR183 HOMER1 UVRAG TNFRSF10B ACSL1 PELI1 KLF2 HIVEP2 FOSB PKIA CHORDC1 TIMP2 VAV3 TCF4 DCK TESK2 FEM1B ZBTB11 GNAI1 IRS2 GALC PIM1 LGALS3 CRY1 GNA13 CSNK2A2 CLEC2B PDE4B CCL20 INTS6 RLF WDR1 OPN3 RAB5A CDKN1C ALDH2 EPHA2 SCPEP1 KPNA4 S100A4 NPAT KATNA1 KCNK7 KIT B3GNT2 CYTH1 RORA HEBP1 GSPT1 RSU1 ACAT1 MED17 UBAP1 PHYH EGR1 FJX1 CTSH ZBTB16 CHIC2 DUSP6 DKK3 NR4A2 PRKCH FAM8A1 FBXW2 TUBA1A EFS DNAJB4	down	***
GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN	0.0026486	0.0264068	0.4317077	0.3407853	1.532676	161	MDM1 CHRNG PLK1 UHRF1 NLE1 IDO1 SLC29A2 YKT6 POC1A EIF2AK1 PPP1R35 SARS2 AKT2 NAA40 THOP1 CKS1B KCNE3 TNFRSF25 DCBLD1 NCAPG NF1 CHCHD2 G6PC3 TELO2 NINL ARF5 ATG9B MRPL4 SMTNL1 NTN3 ZBTB45 PPHLN1 LIPG C16orf58 TBCA CDC42BPG TFAP4 PYGO2 CUBN ESRRA C1orf122 RPS26 PRR11 R3HDM4 TOMM40L TAB1 TMED9 TMEM101 ETHE1 CIAPIN1 EIF4G1 C1orf159 ZMAT2 ALG1 SRPRB FBXO34 SIGMAR1	up	*
ZWANG_CLASS_1_TRANSIENTLY_INDUCED_BY_EGF	0.0000052	0.0001605	0.6105269	-0.2609951	-1.532479	423	SLPI EREG MEG8 LYPD5 USP12 GAPT LRRC8C PTPRE KCTD9 LRRFIP1 EGR2 BACH1 NEDD4L FOSL1 MYD88 TBC1D2 NEDD9 DENND2C IER2 AVPI1 ADAM17 SDE2 CSRP1 EIF5 HIPK3 KLF6 PTX3 RB1 ADRB2 TRAF6 SPRY2 ARHGEF2 HERC3 RHOB LDHAL6A MAP2K3 AGO4 SGTB BIRC2 KIAA0513 COQ10B ZFAND5 STK17B THBS1 ARNTL SOCS2 SOCS5 KLF7 FBXL3 EPGN LBH XCL2 MATN2 OXSR1 KBTBD4 CRIM1 AKIRIN1 TGFB2 RAB6A SRF BTG1 SLC25A25 AREG BCAR3 SGK1 NEK7 ADAMTSL2 RAB8B AQP3 SERPINB8 JUN LRCH1 SH3BP5 C20orf194 PLK3 FOXN2 WTAP ELOVL7 PTGER4 SKIL PNPLA8 HUNK ACKR3 PTGER2 HOMER1 GPRC5A SPRY4 CDK17 EHD1 KCTD10 TSC22D1 MIR23A IRS2 PIM1 CCDC68 LEKR1 ANKRD13A STK40 ANKRD12 ADAMTS15 ARPP19 LINC00319 JUND BMP2K ARAP2 PDLIM5 ABL2 WDR1 SERTAD1 IER5 PARM1 TIAM1 DDX59 ING2 RASSF8 B3GNT2 DUSP7 LYST CYTH1 LDLR NABP1 SHISA6 EHD4 RNH1 CNN2 ARFGAP3 PMAIP1 PIM3 ATP6V0A1 CTSH RNU6-433P KCNE1 ZNF800 SLC19A2 PRKCH ITGB1 SLC38A2 HAS2 ZFP36	down	***
SMID_BREAST_CANCER_LUMINAL_B_UP	0.0049532	0.0424921	0.4070179	0.3470747	1.532158	139	PCSK6 PTGES PTPRT DNAJC12 C17orf75 WFDC2 TOX3 NOVA1 SORD TFF3 IFT122 SLC27A2 NPIPB3 PCLO AGR2 CA12 TJP3 C9orf116 SPAG16 SERPINA3 MCCC2 SLC9A3R1 MRPS30 KRT18 ZNF652 CASC1 ARNT2 G6PC3 AGL TRIM9 SYT1 ESR1 RDH16 KDM4B ANXA9 TBC1D30 ZDHHC11 ALG8 CEACAM5 B9D1 TTC12 YBX2 SYBU	up	*
GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP	0.0012489	0.0150801	0.4550599	-0.2943898	-1.531905	159	FIG4 OTUD1 MYADM VAT1L BMPR2 LINC00622 MANBA NEDD9 FRAT1 ABCB1 SWT1 BTG2 SERINC1 PICALM HDC LCP1 CLK1 PTPN21 OSTF1 DUSP1 ACTG2 CLIP4 RUFY3 SPIN1 ARL6IP5 CPAMD8 CREM PSEN1 CYB5R1 MTMR9 ZNF540 PIK3R1 GRB2 FSD1L FSTL3 RALB XYLT1 TSC22D1 HBP1 CCDC68 EXOC1 CLASP2 LTBP1 TAGLN BNIP3L CTTNBP2NL ITPRIPL2 LMOD1 RTN1 CEBPD TRAPPC8 MMD FAM13B EHD3 RAB2A REEP1 VPS13D TMEM30A CLIP1 PRKCH ITGB1 DYNC1I2 COX20 WDR47 KIDINS220	down	*
REACTOME_PI3K_AKT_SIGNALING_IN_CANCER	0.0054496	0.0454984	0.4070179	-0.3201245	-1.531829	89	EREG KL FYN FGF10 CASP9 HBEGF NR4A1 AKT3 PDGFA FOXO1 CDKN1A EPGN CD80 AREG RAC2 RHOG PIK3R1 GRB2 CREB1 FGFR4 KLB FOXO3 PIK3AP1 STRN CD86 IRS2 FGF2 CD19 KIT PTEN FGFR1 NRG1 MAPKAP1	down	*
MIR513A_3P_MIR513C_3P	0.0000174	0.0004483	0.5756103	-0.2636844	-1.531459	371	SLC6A4 PPARG MBOAT2 PTPRB RUNDC3B TMEM170B JPH4 BAG4 NEDD4L ELF2 RXFP1 WBP4 MOB1B EDEM1 ARHGAP29 CNST RASGRP4 ZDHHC2 RANBP9 SPIRE1 ZBTB21 SLC7A11 ZBTB8A PPP3CA LAMTOR3 ZFYVE16 UBE2D3 TMEM38B FBXO8 EFCAB14 CYBRD1 LIN7C PAQR5 SETD9 ZFAND5 PDE8A PTPRC WASF3 KLRD1 SPRYD7 NUS1 CNOT6L NCOA1 LIN54 TOPORS LACC1 SNX3 GPBP1 ELF1 RYBP PDIK1L VPS37A SAR1A KIF13A APPL1 RAB8B SERPINB8 TMTC1 ARL6IP6 CCDC50 TBC1D12 SKIL EEA1 SP3 IDS CREB1 RC3H1 FSD1L HOMER1 PREX2 YWHAZ CASZ1 ZCCHC9 RNF146 AGFG1 CDK17 PTP4A1 YTHDF3 AZIN1 PPP2CB STRN NDUFA5 JMJD6 ABHD13 TSC22D1 FEM1B TRGC1 NAB1 TPMT ADAM10 CALB1 HACE1 RNF138 TXNDC11 ALDH6A1 HNRNPK ZDHHC21 RBMS3 MAP3K4 CUL3 RASSF8 TTC28 SCAI PTEN CHCHD7 SNX15 MCOLN2 PRKG1 ITCH GSPT1 EIF4A2 HPCAL4 ZNF326 ABI1 KLF15 KALRN	down	***
SENESE_HDAC3_TARGETS_UP	0.0000054	0.0001669	0.6105269	-0.2607985	-1.531324	423	WEE1 CXCL3 CD55 ROBO4 CPEB2 LPXN PTPRB BMP2 CD44 TMOD3 CCDC88A BACH1 NEDD4L GTF2I INPP5A RBM14 OTUD4 TGFBR2 TRIB1 GGA2 DNAJB14 ATP2B1 NCEH1 MALAT1 GM2A BTG2 SPIRE1 KLF6 GLS PTX3 SLC7A11 ZNF697 SLAIN2 PPP3CA RB1 SLC25A37 SFRP1 AKT3 SPTBN1 MAPK8IP1 TFRC MCL1 RHOB PTPN12 TBC1D9 KCNMA1 SLC12A4 TNFSF15 TPP1 MYO1B ABCC4 ATF3 TLR4 CCND2 PLEKHB2 ELK3 SLC6A6 IL7R UBASH3B TBC1D4 IL24 USP16 AKIRIN1 ACTR2 BTG1 PDK4 CREBRF FMNL2 VAMP3 CREM PHTF2 SNAP23 RAB8B OASL SF3B1 CPEB4 SLC14A1 LTBP2 JAK1 MBNL2 IDS ATP13A3 GTDC1 CXCL5 YWHAZ TNFRSF10B GFPT2 CDK17 HIVEP2 PPTC7 PKIA TRAPPC10 SAV1 STRN ATP6V1A GALC MAP3K2 SOD2 KYNU GNA13 ADAM10 SERINC3 PDE4B CALB1 ETS2 SNHG16 MBNL1 CCL20 GEM CEP170 OPN3 CDKN1C ORMDL1 MEX3C PSME4 G3BP2 TRAF1 STK4 NFKBIA JMJD1C TIMP3 DOCK4 GRB10 IQGAP1 MAPKAP1 MIER3 PMAIP1	down	***
E2F1_UP.V1_UP	0.0036269	0.0337691	0.4317077	0.3402806	1.531324	162	MCM10 UBE2T PRIM2 MRPL46 E2F8 STIL AURKB E2F3 MCM4 TYMS PRC1 UQCC1 RND2 BUB1 TOP2A POLA2 WDHD1 CHAF1B LMNB1 SLC9A3R1 CHEK1 DCTPP1 CAD ERCC2 HSPBP1 PARP1 THOP1 DRC1 ARHGAP39 UCK2 PACS1 PHF12 DNA2 KIF2A FEN1 SSX2IP EZH2 TAF6 EIF6 SPEF1 DLGAP5 TK1 CASP7 PKP4	up	*
GO_CIRCULATORY_SYSTEM_PROCESS	0.0000068	0.0002000	0.6105269	-0.2618124	-1.530844	409	SLC6A4 EPAS1 HSPB7 RAMP3 ACVRL1 HMOX1 TEK OLR1 ACE EDNRB PPARG P2RY1 EMP2 RAMP2 CDH5 FYN CAV1 NEDD4L ADRA1D BMPR2 CYB5R3 TBXA2R HMGCR FXYD2 MEF2A CDC42 GAS6 CYP4A11 SCN5A HEG1 RHOA PDE2A TBX2 ATP2B1 PTPRM HBEGF ADA CACNA2D2 KCNK3 ADRB1 DES ADRB2 CES1 TCAP PDE4D TMEM38B FOXC2 FLI1 MAP2K3 ROCK2 TNNC1 KCNMA1 PTPRO TACR2 PTAFR ROCK1 GAA NPR3 PER2 P2RY2 KCNMB1 ID2 XCL2 PIK3C2A SMAD7 ZMPSTE24 RAP1GDS1 FXYD7 GNAI2 CALM2 TGFB2 PRCP KCNA5 SLC8A1 SCN4B SGK1 HRH1 CTSZ ADRA1A PDE5A RCAN1 GSTO1 PTGER2 NPR1 PRKACA SUCNR1 CELF2 CD34 GPR37L1 CALM1 TREX1 SLC4A5 MME CPA3 FXYD6 TGFB1	down	***
GSE27786_CD8_TCELL_VS_NKCELL_DN	0.0010959	0.0136639	0.4550599	-0.2880245	-1.529960	179	FFAR4 P2RY1 MIR22HG HSD17B11 RTN3 AKAP7 CLEC10A MKNK1 NEDD9 NFIX TOR1AIP1 RB1 ARHGEF2 TMEM38B LRP4 PRKD3 KLF9 PLEKHM3 RIT1 C9orf72 AXL HPSE FRMD4A INHBA ADIPOR2 SLC6A6 ANXA3 VCPKMT VAMP3 WASF2 PHTF2 KIF13A OASL SERPINB8 ATP6V0B SNX2 ATXN1L MBNL2 PRKACA YWHAZ SNX9 SOD2 BRI3 ACADL ACYP2 GEM HSPA2 CPQ DCTN4 SPIB ARHGAP18 ALDH2 ACTB TMCC3 SPATA13 KLC1 ZNF326 CYBA CHP1 TMEM30A	down	*
GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP	0.0007455	0.0101018	0.4772708	-0.2874547	-1.529876	177	SIDT2 DENND5A SNX10 CAT LY86 S1PR1 MANBA CD1C TGFBR2 GGA2 KIAA0355 ITSN2 ATP6V1B2 SRSF5 GCA RAP1GDS1 MAPRE2 ARHGDIB SNN STK24 RPL17 USP25 PKIG FRY CDC40 KIF13A RBM34 ESD HMBOX1 IRF8 PSTPIP2 MORC3 REL EGLN2 SLC25A24 PKIA CD74 GSAP DCK CRYZL1 TSC22D1 DYNC1LI1 SLC24A1 KYNU ZNF267 PPID RBL2 TNFAIP8 ESYT1 LYST FAM13B WDFY3 ENDOD1 ING1 BBS7 CD79B PAX5 SGPP1 ZNF22 PNRC2 RNF111 RPA2	down	*
E2F_Q3_01	0.0027589	0.0272517	0.4317077	0.3321112	1.529862	195	CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A MCM8 EPHB1 RANBP1 WDR62 CASP2 MELK PAQR4 AP4M1 NUP155 POLA2 MCM7 PRKDC MCM3 TOPBP1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 CDK1 POLE2 GMNN E2F1 UNG EZH2 TNPO2 THAP8 KPNB1 DNMT1 ZNF687 ACBD6 FANCG PELP1 INTS7 NDUFA11 DHX40 DNAJC11 RHD KDM3A SASS6 PPP1R8 HMGA1 PELO MCM6 SRSF1 GINS3 OVOL2 STK35 ATAD2 EIF3K PATZ1	up	*
MIR6079	0.0025312	0.0256451	0.4317077	-0.3043396	-1.529133	118	PRX ATXN3 CORO1C BMPR2 ZCCHC2 OTUD4 EPB41L3 KIAA0355 MS4A1 HIF3A HMGN1 KCNMA1 ADO MVB12B MYRIP DSTN ILDR2 PRICKLE2 VEPH1 CDKN2AIP FOXN3 SACM1L CREBRF MITF YWHAZ PTP4A1 MSMO1 MME HNRNPD TIMP2 ATP6V1A C16orf72 SCARA5 SPOCK2 ATAD2B CHURC1 RTN4	down	*
GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN	0.0005910	0.0084412	0.4772708	-0.2875919	-1.529120	175	IL1B LRRFIP1 BAIAP2 RBM14 BCL2A1 HPS5 ATP2B1 LTBP4 HBEGF ADAM17 PAQR3 GLS NFE2L2 NDEL1 SPRY2 ZFYVE16 SRGN MAP2K3 ADO NFKB1 ATF3 CDS2 VIM HOPX MATK EMP3 NSMAF PGD PNO1 CYCS RHOG TMEM251 IPO7 SP3 HOMER1 NOL7 CDK17 HIVEP2 PEA15 BAZ2B ATP6V1A NAB1 PDCD1 GNG5 CD81 MBNL1 GEM ANKLE2 WDR1 UBE2D1 IPO5 TRAF1 COPS8 ZNF165 PSMD9 NUP160 FEZ2 SNRPG BCL10 TSC22D2 GABPB1 KLHL9 ORC4 CFLAR GTF2H1 DUSP2 IVNS1ABP SENP6 ADAM19 GNL2 SUCLA2 EIF4A3 PSMD14 EZR AGO2 FASLG PTPN22 SACS SEC62 PRNP	down	**
GSE3982_DC_VS_TH2_DN	0.0022339	0.0232960	0.4317077	0.3382739	1.528995	170	TRIP13 KIF20A FANCI TROAP CENPF POLQ TFF3 PTTG1 SFXN1 CCNB2 BCL2L14 TYMS ORC1 GINS4 AGK HMMR DPY19L2P2 KIF15 THBS4 TPR KIF2C MPHOSPH9 PDCD5 PASK GPSM2 DNAJC9 PERP MB ASF1B BIRC5 TESC PSMC4 LAPTM4B DLGAP5 SPTBN2 GALNT3 COX10 MARCKSL1 AAMP SUPT16H TWIST1 KIF21B GINS3 DOLPP1 ATAD2 CCNA2 ARHGAP5 ARHGAP11A PAXIP1 ZNF142 EIF4G1 E4F1 SEPHS1 SYNE2	up	*
GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_UP	0.0026223	0.0262364	0.4317077	-0.3024536	-1.528931	122	SOWAHC TBX3 HSD17B6 EGR2 CCRL2 IER2 BTG2 NR4A1 SPRY2 MYOZ3 COQ10B ADAMTS9 CXCL2 ATF3 MAFF TGFB2 PROCR SLC25A33 SLC25A25 AREG IL6 KCTD12 PLK3 DUSP8 PPP1R15A REL HOMER1 FOS FOSB WNT11 PARD6A MIR23A DUSP5 IRS2 CEBPD TOB2 HES2 EDN1 TMCC3 NRG1 ELFN1 PMAIP1 EGR1 SERPINE1 NR4A2 ARL4D ZFP36 KCNJ1 DNAJB4 DPF3 AKAP12 NFIL3 NR4A3 PTGS2 IMPACT NFKBIZ	down	*
GO_NEGATIVE_REGULATION_OF_IMMUNE_RESPONSE	0.0025312	0.0256451	0.4317077	-0.3042717	-1.528792	118	GPR17 FOXF1 HMOX1 PPARG CD55 SAMHD1 CLEC12B IL1RL1 ANXA1 HLX SERPINB9 GRN CRK IL10 SOCS5 PTPRC SMAD7 IL7R C4BPB TGFB2 CD160 PSMA1 RC3H1 TBX21 YTHDF3 TREX1 CR1 TGFB1 YTHDF2 NLRP6 CNOT7 PDCD1 LGALS3	down	*
GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN	0.0046187	0.0402942	0.4070179	0.3366671	1.528746	177	NUP107 GGCT RACGAP1 POLE ALDH18A1 CCNB2 CCNF ZWINT MYL6B RUVBL2 EXO1 KNTC1 BUB1 ERAL1 MCM3 THYN1 ORC6 PFKP PKMYT1 ETFA MNAT1 CKS1B CMAS GMNN MCAT MRPL17 FADD SNRPE RTCB FOCAD CHCHD2 GNPAT FAH GINS2 CCDC51 PSMD2 ENPP2 PSMB3 BCL2L1 PELO STAMBP MCM5 SNRPD1 LSM4 KLHL7 NUP62 NDUFV1 DCPS ATOX1 RAD51 CPOX EIF4G1 POP4 SEPHS1 PPIA COX17 ERLIN1 TBC1D10B FASTKD3 BATF GCNT1 MTHFD2 COX6A1 SMC4 CTPS1 PSMD8 ACOT7 P4HA2 HMBS MRPL35 MRPL13 EDC3 RFC3 CNOT6 GALK1 TARDBP GIGYF2 PSMC2 SNRPB SDC4 PARK7	up	*
MIR7162_3P	0.0003890	0.0060463	0.4984931	-0.2853304	-1.528556	192	TRIM71 ANGPT4 DLC1 KLF13 SECISBP2L RAB3C THAP2 QKI GPCPD1 EML1 TBC1D7 BMPR2 GNPTAB FAM49A SPCS3 SLC19A3 SH2B3 STARD9 FOXP1 PLXNA4 RB1 RUNX1T1 LEPROTL1 MED6 FMNL3 DPH3 RBMS1 TEF USP44 CCND2 MYH11 VEPH1 HTRA4 PRDM11 UTRN UHRF2 MTMR9 APBB2 FAM43A GCNT4 UVRAG EGLN2 PPM1F GPR3 YTHDF3 SRSF6 VAV3 PDS5B SH3RF3 ATXN1 ADAMTS15 ADAM10 ABL2 ZNF583 XKR8 CEBPD TAB2 ALDH6A1	down	**
MIR122B_5P	0.0016385	0.0184215	0.4550599	-0.2878071	-1.527924	174	RAB11FIP1 P2RY1 CLDND1 THBD DDX6 FOSL1 NR3C1 PKHD1L1 UBL3 SBDS RAPGEF4 RAP1A ITGA5 EIF5 PBX3 PICALM ADRB2 ZFYVE16 ITSN2 CYBRD1 RAB12 DRAM1 CLIC4 SIK2 PIK3C2A ELMSAN1 DSTN PEAK1 MYO1C PPIL4 ID4 VPS37A NXF1 C2CD2 KCTD12 MAP4K4 APBB2 VPS26A TOM1L2 PANK2 RHOQ SPOP ZNF596 PCDH17 ATXN1	down	*
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_UP	0.0009118	0.0118049	0.4772708	-0.2918167	-1.527910	166	SC5D PTPRB SIK1 HSD17B11 SAMHD1 CITED2 DPEP2 TNFRSF8 PTS PTPRM SLC7A7 ASAH1 NAAA PDE4D PPP3CC CDADC1 ITPRIP SGTB PSTK KLF11 TPP1 ST7L DUSP1 RNF139 UBASH3B MYH11 MAFF SNN TBC1D5 JUN OXNAD1 LIMD1 SNX29 ATXN1L SUGT1P3 FBXL16 SLC10A7 OGFRL1 TAGLN2 PTP4A1 BIN2 FAM204A FAM228B IRS2 KCNA3 TOB1 COMMD9 HAUS3 CGRRF1 EPHA4 BRWD1 TTC32 TTC28	down	*
GO_MESENCHYME_DEVELOPMENT	0.0001742	0.0030569	0.5188481	-0.2806065	-1.527829	223	SEMA6B SEMA3G SEMA6A TMEM100 ACVRL1 FOXF1 EDNRB GLIPR2 IL1B WNT4 BMP2 ENG FOLR1 CORO1C CITED2 BMPR2 FGF10 TGFBR3 TGFBR2 ZEB2 SEMA6D TBX2 SEMA3B FOXA2 ADIPOR1 RGCC SFRP1 WNT3A TCF7L2 FOXC2 NODAL TAPT1 SNAI1 SDCBP DAB2 SMAD7 TBX5 ACTG2 PEF1 DCHS1 HES1 TGFB2 RBPJ PPP2CA IL6 NOTCH1 DDX17 DDX5 KBTBD8 POGLUT1 PKD2 WNT11 EPHA3 TGFB1 TGFB1I1 CLASP2 SMAD2 LDLRAD4 EPB41L5 OSR1 SEMA4A RTN4 TIAM1 S100A4 RET EDN1 PTEN FGFR1 NRP2 NRG1 ZFPM2 SMAD4	down	**
QI_PLASMACYTOMA_UP	0.0001742	0.0030569	0.5188481	-0.2805811	-1.527691	223	RBP4 IL17RB SWAP70 SNX10 LRRFIP1 LY86 TMOD3 MARCO CD22 FGR DNASE1L3 RNASE1 LCP1 RB1 CD37 ARRB1 EPOR CASP1 VASP STK17B CCL3 AXL ID2 CD53 ALOX5AP PLEK KLRD1 ACTG2 UBASH3B ARHGDIB ACTR2 HCK MTPN SRF BTG1 ARL6IP5 IL2RB RAC2 IFNGR1 WTAP SNX2 IRF8 GRB2 RPS6KA1 CAP1 CD7 RASSF2 CST7 MOB1A TGFB1 TFEB EHD1 GNB4 CCR1 ARAP2 IL18 IL18RAP LAT WDR1 SEMA4A CDC42EP3 SPIB UBE2D1 SP100 TRAF1 CD19 NFKBIA ABI3 KIT CD3G ANXA11 CNN2 IRF2 CNR2 CLEC4E ITGB1 ZYX NFAM1 PTGS1 BDKRB2 GNG11 DNAJB1 DAPP1 CD3E SLC43A3 IRF1 TRAT1 SH3BP2 ITGA6 CD4 CASP3 DUSP2 PLEKHO1 PLXNC1 ARAP1 FLT3 CAPG SLAMF1 DPP4 TUBB3 TLN1 PFN1 CD47 FGL2 PTPN1 STK10 ADCY7 HCLS1 CD3D LSP1 CCR5 BLK	down	**
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP	0.0000003	0.0000144	0.6749629	-0.2471769	-1.527362	657	RAB11FIP1 LPIN2 SLC12A6 TMEM52B OSBPL11 SECISBP2L CD55 CPEB2 C18orf32 DPYSL2 RAPGEF2 PTPRE LRRFIP1 TTC7B ARRDC4 FIG4 TMEM170B FYN INPP5K SEC22C PRAM1 GPCPD1 PLEKHA1 YPEL5 MEF2A BCL2A1 IL1RN EPB41L3 TXNIP NUMB EDEM1 KIAA0355 SH2B3 NCEH1 B3GNT5 HBEGF CHMP1B EIF1 CLEC7A EIF5 CSGALNACT2 KLF10 PAG1 SLC7A11 ADRB1 RBM4 MOB3C IL18R1 SLC25A37 PDE4D CD37 TAPT1 AGO4 MTMR6 ITPRIP SGTB EPOR BST1 ZSWIM6 KLF4 ZCCHC24 ITM2B KLF9 UHRF1BP1L MAP1LC3B MYO1B CLIC4 SCAF4 CCL3 SSH1 RIT1 CDKN1A C4orf33 ST7L PTPRC ATF3 CTBS RECK ARHGAP9 FCER1G ALOX5AP PLEK NUTM2A-AS1 HTT N4BP1 MAFF ANXA3 LIN7A NCOA1 HCK LACC1 BTG1 NINJ1 RBM39 TFAP2E TRAF3IP2-AS1 CTSS PHACTR2 PGD RAB8B UTRN HCST SEC14L1 HECA CD48 CPEB4 USO1 ETS1 TYROBP CCDC50 NXPE3 CSTA JAK1 PPP1R15A SKIL IFRD1 GLIPR1 PNPLA8 HSPA13 MBNL2 IDS SERPINB6 ENTPD4 FSD1L SUCNR1 OGFRL1 TNFRSF10B APH1B GAS6-AS1 RNF146 ACSL1 SLC3A2 SLC25A24 CDK17 AZI2 RBKS PKD2 MYL12A BIN2 TTBK2 CR1 TIMP2 EHD1 TCF4 DCAF5 SMCR8 SERPINB1 TGIF1 BAZ2B VAMP4 FPR2 SH3RF3 DUSP5 CNOT7 ATXN1 HBP1 GPR84 TAGAP GABARAPL1 PHF11 RGS2 VPS39 KAT2B MR1 ATAD2B HACE1 RNF2 BMP2K ARAP2 BNIP3L IL18 NEK1 IL18RAP CCDC69 SEMA4A ALDH6A1 SP100 DDX59 METTL7A PCBP1-AS1 NHLRC3 STK4 C7orf31 CCDC92 RET ADORA2A RAB2B FOXJ2 DNAJB9 KIF1B GRB10 NABP1 WDFY3 MIER3 ARFGAP3 TNFRSF10D PMAIP1 MED17	down	***
MIR4778_5P	0.0022106	0.0231661	0.4317077	-0.2970715	-1.527259	147	SLC6A4 AKAP5 ABHD5 SLC12A6 HMGCR SLC15A3 EOGT EPB41L3 ABCB1 SLC36A4 ABCG1 NRARP CYP4X1 SETD9 USP2 CD302 UBE2B DSTN PHTF2 HECA PIK3R1 CREB1 HOMER1 CGGBP1 CD164 ZRANB1 CCP110 SLC24A1 MACF1 ZNF267 PDE4B INO80D FBXO25 MBD5 KLLN GLUL LIMCH1 RORA ITCH CNTNAP3B SMAD4 GPALPP1 FJX1 SH3GLB1 CCNT2 EBF1 YWHAB PIAS2 MTSS1 UBE2N ANKHD1 CRIPT PTPRQ PJA2 SRRM1 KCTD18 ENPEP BICD2	down	*
GO_CELL_CHEMOTAXIS	0.0001388	0.0025304	0.5188481	-0.2782617	-1.526907	234	CXCL3 IL1A SWAP70 CXCL16 EDNRB IL1B CCL3L1 CCRL2 C5AR1 S1PR1 IL1RN GAS6 IL23A ANXA1 PLA2G7 HBEGF SBDS ADAM17 HSPB1 NR4A1 JAM3 CRK PDE4D IL10 CCL22 PTPRO BST1 THBS1 CCL3 CXCL2 CCL4 SFTPD XCL2 FCER1G DUSP1 OXSR1 AKIRIN1 TGFB2 NCKAP1L FLT1 IL6 NOTCH1 HRH1 RAC2 RHOG CCR7 DAPK2 ACKR3 GPR183 CXCL5 CD74 BIN2 CCR4 VAV3 ITGA9 FPR2 LGALS3 KLRC4-KLRK1 CCR1 GPR18 ADAM10 PDE4B CCL20 CCR6 FGF2 ARRB2 TIAM1 CXCR4 CCR9 EPHA2 PARVA KIT EDN1 KLRK1 MTUS1 LYST FGFR1 DOCK4 IL16 ANO6 GREM1 SERPINE1 C5AR2 CNR2 CX3CR1 C5	down	**
GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_12H_UP	0.0028300	0.0278149	0.4317077	0.3368276	1.526361	175	TRIP13 SCIN RUVBL1 MCM10 BUB1B C17orf75 TRIM17 PRIM2 ESPL1 RBBP8 ORC1 CCT6A VILL SPDL1 WDR62 EME1 POLD2 KIF11 PASK CHAF1B SPINT1 MRPS11 ETFA ZCRB1 NUSAP1 ANAPC5 SPATA6L CENPJ GNB1L C1orf112 NPM3 DNA2 WDR31 SPAG5 NF1 CHCHD3 C19orf44 FOXRED1 MORN2 ZNF239 SYT1 PRMT7 LRRC20 NRF1 NUP85 ATAD5 CENPK PSMB3 BRD8 RPA1 KPTN LSM4 CEP152 MSH2 MCU WDR76 AURKAIP1 NTN1 CENPE SWI5 NMT1 EPHB4 SMARCB1 C4orf46 NUP93 PARP2 RCN2 UTP18 ZC3HC1 HINT1 FOXRED2	up	*
ACATTCC_MIR1_MIR206	0.0000470	0.0010288	0.5573322	-0.2746454	-1.526333	274	TSPAN4 KLF13 TTC7B BDNF BAG4 CORO1C CITED2 QKI VAMP2 HMGCR CDC42 TGFBR3 CBL SEMA6D ZBTB4 TRA2B OLFML2A PICALM FOXP1 EIF4E SFRP1 ANKRD29 TFEC HNRNPU SLC7A2 CPED1 HMGN1 LIN7C CDK9 UBQLN1 TMSB4XP8 WDR48 PAFAH1B1 C2orf69 SLC25A25 PDIK1L CREM SRSF3 GAS2L1 ETS1 DDX17 DHX15 SNX2 DDX5 MSANTD2 YWHAZ CEBPZ TAGLN2 CDK14 YPEL2 HIVEP2 SLC35F1 FOSB DGKG NAP1L5 AZIN1 PBRM1 AP1G1 VAMP4 RSBN1L ATP6V1A MEIS1 ADPGK PHLPP2 JUND RNF138 PDLIM5 CTTNBP2NL SEC63 ACAP2 TMOD2 MEX3C HNRNPK TIMP3 EDN1 RNF38 MMD	down	**
GSE7852_LN_VS_THYMUS_TREG_UP	0.0006504	0.0091215	0.4772708	-0.2870489	-1.526233	175	CXCL3 ARHGAP31 GPR15 HVCN1 SPN LPXN RUNDC3B PEAR1 ABCB1 PDE2A ARSB MS4A1 SRGN CYP4V2 ARRB1 SYNPO AGO3 CASP1 ATP6V1D ABCC4 TMBIM1 NR1D2 HOPX SHE ELMSAN1 BRF2 GNAQ UBASH3B MYH11 BCLAF1 HLA-DQA1 TANC1 HGSNAT FOXN3 RPS6KA2 KIF13A WSCD2 ST6GALNAC4 PTGER4 PRKCE PTGER2 SH2D4B CST7 NDST1 SNX9	down	**
GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN	0.0006899	0.0095243	0.4772708	-0.2883622	-1.526105	172	LPIN2 FYN DDX6 CORO1C GTF2E2 IDI1 APIP NUDT9 CD9 IL1RN ANXA5 LITAF SLC7A11 LCP1 PPP2R2A NDEL1 LAMTOR3 SRGN TUBB6 STAT5A SORBS1 CDIP1 ARNTL ATP6V1D SOCS5 FBXL3 CDKN1A ID2 M6PR EXOSC8 IL7R EBF2 RAB8B DHH STAT4 MAP4K4 PTGER4 IFRD1 CD74 EHD1 AP1G1 KCTD10 C16orf72 GABARAPL1 STX12 CRY1 GNA13 CSNK2A2 FKBP1A SLC31A1 ARIH1 ACTB TDRP	down	**
GTGACTT_MIR224	0.0018630	0.0202525	0.4550599	-0.3024451	-1.525594	131	CPEB2 DPYSL2 EGR2 QKI HMGCR CDC42 IL1RN CIT TRA2B PTX3 NR4A1 HNRNPU UBE2D3 KCNMA1 ITM2B ZNF423 ID3 CDK9 MAFG FAM49B UBQLN1 AFF3 ZDHHC20 FOXN3 SERTAD2 TMEM9B MYLIP CREBRF KCTD12 WTAP MBNL2 KBTBD8 CGGBP1 EPC2 FOSB AZIN1 NUP153	down	*
GSE1112_HY_CD8AB_VS_HY_CD8AA_THYMOCYTE_RTOC_CULTURE_DN	0.0014313	0.0166322	0.4550599	-0.2912080	-1.525570	157	CXCL3 EREG IL1A CD55 IL1B LTA4H PID1 COQ2 FYN RADIL BCL2A1 ATP2B1 PTPRM CARD16 FAM124A MPHOSPH6 BNIPL TCF7L2 AGO3 CASP1 PLAUR STK17B STX3 CXCL2 ALOX5AP PINK1 IL24 KREMEN1 PROCR FMNL2 DDX60L NSMAF SH3BP5 CELF1 CCDC50 PNPLA8 ZBED5 SNX9 TGIF1 TSC22D1 IRS2 CCL20 BNIP3L CDC42EP3 ING2 BCAT1 RET IL16 RABGEF1 LINC00922 CRBN CLEC4E SLC19A2	down	*
GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN	0.0011670	0.0143416	0.4550599	-0.2899221	-1.525509	168	ACP5 PLEKHA1 STX11 NR3C1 MANBA EPB41L3 KIAA0355 SH2B3 NDUFAF7 IFI30 NLK ADARB1 PTGIR DRAM1 MAP1LC3B PDE3B SIK2 CD302 CLK4 DUSP1 PLEK N4BP2L1 GNRH1 HCK FOXN3 MYLIP RBPJ DCP1A PDE6B BTD CCR7 DAPK2 TNFRSF9 ZBED5 POGLUT1 PNPLA2 SPOP TGIF1 TSPAN14 HBP1 CPT2 N4BP2L2 SYT11 BNIP3L TIAM1 PTCH1 MEGF9 NFU1 AFTPH CD70 CSF2RB NR4A2 CX3CR1 AOAH PDCD2 TREM2 GPR137B STX16 IL5 ATP8A1 ZFYVE21	down	*
GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN	0.0048365	0.0416841	0.4070179	0.3453266	1.524977	137	EYA1 GABRB3 BHMT DNAJC22 GINS1 CDK4 ASIC1 FOXE1 FA2H ANKRD24 CALML6 KNOP1 CYP27B1 CDC25A CXCL10 DLG1 BOD1 CXCR5 AMACR CCDC58 FUT2 CXCL11 CCDC61 DMGDH GJB3 EFCAB1 CPXM1 EVC2 DVL3 COL9A2 COX7C C1orf131 CASP7 COLEC11 GEMIN5 DAP3	up	*
GSE37605_NOD_VS_C57BL6_IRES_GFP_TREG_UP	0.0016640	0.0186188	0.4550599	-0.3017358	-1.524296	132	SOSTDC1 PLEKHF2 CGNL1 STX11 NR3C1 NFATC3 PEAR1 FGR ANXA1 ATP2B1 DNAJC3 LTBP4 RNF125 STOM SLAIN2 GRN GPA33 ARNTL KIF26A CDKN1A UXS1 PIK3C2A PLCD1 PTH1R NCOA1 MYO1C FRY NDNF C1QA NDST1 XYLT1 IRF5 CNTNAP1 KCNA3 APLP2 SPOCK2 PHLPP2 CCR6 GPX3 TIAM1 ADORA2A B3GNT2 IQGAP1 LPAR6 PMAIP1 EGR1 C1QB	down	*
BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN	0.0000176	0.0004518	0.5756103	0.3052971	1.524089	561	PCSK6 DDX11 HELLS KIF20A GALNT14 MDM1 HJURP MCM10 BDH1 ELOVL6 DEPTOR ZDHHC4 GALNT6 NEK2 IGF2BP3 PAGR1 PTPRN2 ZFHX4 COA1 KIF18B IRS1 HILPDA NDUFS6 AP1S1 AURKB SIX1 SOX9 THTPA HOXB7 RAD54B FERMT1 ORC1 CCNF GALNT10 GINS4 MANSC1 TTLL4 DNPH1 EXO1 NUDT1 CISD1 PAQR4 MKI67 EMC9 KIF15 POLM CYP24A1 BUB1 FANCA TOP2A DPY19L1 AURKA ZNF112 APOL1 TMEM177 CARD10 VANGL1 POLA2 ATR ZNF174 MPHOSPH9 RRM2 TTLL12 RHOBTB3 MCM3 BLOC1S1 LMNB1 MCCC2 RNFT2 THYN1 CBY1 DCTPP1 THAP10 MRPS11 BRIP1 FNTB NAA40 RGS4 DET1 WWC1 PIGO SKP2 PSRC1 CKLF GEMIN4 PON2 ZNF512B ISOC2 CDKN2C IGFBP5 CDK1 WDR5B PPIC POLE2 BIRC5 C1orf112 POLR3K E2F1 ACP6 MCAT DNA2 NEIL3 SSX2IP COA4 ETFB TSPAN1 FOCAD FAM86C1 NRGN DGCR6 SNRNP25 CCNE1 FANCF SLC26A2 ADAM12 ATP6V0E2 ADAT1 LMNB2 UROS MRPS34 DHODH OSBPL3 SLC37A4 USB1 SPTSSA COPS7B PPOX DTYMK ZNF239 MSRB2 GINS2 PKP4 PRMT7 ENC1 CLTB CDC7 GEMIN6 DHRS1 USP18 HNF1B YLPM1 AP3M2 SLFN12 BCL2L1 MRPL24 BLCAP SURF2 POLR2I RNASET2 ALG8 FARSA PMS1 TM7SF3 CCNA2 PRIM1 ZNF93 MLXIP GTF3C2 PDF FKTN GBP1 WDR77 HK2 APBA2 N6AMT1 RSAD1 NME7 CDK5 AGBL5 WDR76 NUBPL TNS3 CHPF2 GMPR2 BRICD5 GGCX SEPHS1 FGFBP1 NNMT PNN UBTF NDUFB7 RRS1 ACSL5 FBXL18 TMCO6 ERLIN1 PARP2 C9orf40 CSTF1 MLLT11	up	***
GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP	0.0015334	0.0175480	0.4550599	-0.2879271	-1.523862	169	RBP4 CXCL16 PPARG LRRC8C P2RY1 EMP2 GPR65 BMP2 LY86 AQP9 GAS6 CBL HBEGF NLK GRN SRGN RHOB AHNAK MED11 ST3GAL2 NES PRKD3 ITGAX CDS2 EPS15 SPRYD7 DEGS1 TANC1 CNRIP1 VWF HEXB RAB6A SACM1L NINJ1 TMOD1 ESD C20orf194 ETS1 APBB2	down	*
GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN	0.0038059	0.0349403	0.4317077	0.3356586	1.523077	176	KLC3 FOXM1 FAM81A CDC45 UBE2T KIF18B PIF1 DEPDC1B IQGAP3 E2F8 POLE STIL FIGNL1 TYMS WDR62 MELK HMMR EXO1 BUB1 TPBG POC1A ICA1 CPD PASK CDC25C CHEK1 ORC6 CKAP2L RAD51AP1 BRIP1 BLM SLC25A10 INCENP KNSTRN ADAP1 DNA2 SLC12A8 DAP RAPGEF5 SNRNP25 INTS7 HMGN3 CASP7 GINS2 KIF20B LCLAT1 FHL2 ERBB3 RPA1 HMCES IL12RB2 RCC1 STK39 NUP62 CYTH2 MMP16 AMDHD2 CARHSP1 RPP25L KIAA1522 ZBTB32 FAXC RORC NUP93 CYP11A1 CYB5B ESM1	up	*
GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP	0.0012255	0.0148826	0.4550599	-0.2867203	-1.523032	179	SIDT2 CD52 SWAP70 SLC47A1 MIR22HG TRPV2 COQ2 BACH1 FOSL1 PCOLCE2 FUCA1 EOGT TEX2 EIF4A1 HSPB1 PICALM LAIR1 SIRPA CES1 CYBRD1 PPT1 ACSL3 CPVL PXDC1 UHRF1BP1L SLC7A8 CEBPA STX3 ERP44 ITGAX TM6SF1 INHBA MATK HCAR3 CTSS TREM1 CD83 CXCL5 NDUFV2 ACSL1 AZI2 NOP10 PSMD12 FXYD6 TSC22D1 GALC CPT2 APLP2 CLASP2 CLEC2B PLA2G15 AMD1 CEP170 RTN1	down	*
GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN	0.0057365	0.0473536	0.4070179	0.3417557	1.523028	146	ENTPD2 CPLX2 SLC6A3 PCDHGB4 GOLGB1 RAB36 DPYSL4 BPHL NUP155 EIF2AK1 GPSM2 SEC61A1 SLC9A3R1 CLIP3 ZKSCAN1 HSF4 PTGDR2 SNAPC4 SLC28A2 ERCC2 NRTN EFCAB11 KRT18 ATP2A1 SUN1 MCAT SSX2IP NF1 SRD5A1 CDK3 CCL21 COG2 DNMBP COPS6 SEC14L2 CLINT1 TFAP4 HMCES KATNB1 RHOBTB1 ANK3 EPCAM MICAL3 ALMS1 ZNF212 STK38 ZNF169 CSNK1G2 ABCF2 CCDC9 BMS1	up	*
GO_NEGATIVE_REGULATION_OF_NEURON_PROJECTION_DEVELOPMENT	0.0025491	0.0257471	0.4317077	-0.3020090	-1.522680	128	TNR DAB1 SEMA6B SEMA3G SEMA6A DENND5A RAPGEF2 RHOA SEMA6D ASAP1 SEMA3B PAQR3 PPP3CA WNT3A ZNF365 LRP4 PTPRO TRIM46 VIM PAFAH1B1 RUFY3 KREMEN1 SRGAP2C KANK1 MYLIP PSEN1 CTSZ BAG5 IFRD1 RTN4R TRAK2	down	*
GO_CELL_DIVISION	0.0000405	0.0009094	0.5573322	0.3075384	1.522390	498	HMGA2 CCNO TP63 SPICE1 HELLS KIF20A CUZD1 RUVBL1 CHEK2 BUB1B NEK2 CCNB1 CENPF TIMELESS STOX1 KIF18B NDC80 CDCA2 CDK4 RACGAP1 E2F8 KIF14 ANLN ASPM PLK1 NUF2 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 TPX2 CCNB2 RBBP8 CDC25A PRC1 NOX5 CCNF CIB1 LIG3 MIS18A ZFYVE19 NCAPD2 ZWINT CDT1 SPDL1 LMLN HAUS5 KIF23 CEP55 BOD1 CUL7 KNTC1 KIF3B BUB1 TOP2A MAP10 AURKA THBS4 SYCP2 TPR KIF2C MAD1L1 CD2AP CENPW CXCR5 CDCA5 FSD1 NSUN2 KIF11 GPSM2 CDC25C MDK LIG1 ORC6 MAD2L1 SPC24 BRIP1 BLM ERCC2 PARD3 RECQL5 PSRC1 INCENP KNSTRN CKS1B NCAPG2 NUSAP1 ANAPC5 CDK1 CENPJ BIRC5 DIS3L2 NCAPG VANGL2 KIF2A ANAPC7 SPAG5 RAB11FIP4 SAPCD2 MAD2L2 KLHL22 GIPC1 MYO19 CEP63 CCNE1 RHOC CDC23 CDK3 TACC3 LLGL2 FZR1 PKP4 CLTA KIF20B ANAPC1 JTB CABLES2 CDC7 PTN CENPV CKAP5 CDC20 ROPN1B EFHC1 ALKBH4 BCL2L1 CHMP4C PELO STAMBP CENPT CKAP2 HAUS6 NEK4 KATNB1 RTKN RCC1 CCNG1 HAUS4 TXNL4A ANK3 ESRRB NUP62 MICAL3 CCNA2 ANAPC2 USP39 CEP164 ZWILCH CHMP1A MARK4 CHMP2A CDK5 SMC2 MAU2 CENPE E4F1 GOLGA2 CDC25B UBE2C DCDC1 NCAPD3 TUBA1C MAP9 E2F7 CLASP1 BRSK2	up	***
GO_REGULATION_OF_NIK_NF_KAPPAB_SIGNALING	0.0061553	0.0499577	0.4070179	-0.3180082	-1.521702	89	RTKN2 SASH1 IL1B IL23A RHOA MIR146A LITAF ADIPOR1 IL18R1 TRAF6 AGO3 BIRC2 LIMS1 TNFSF15 TLR4 ZFP91 MALT1 RC3H1 TNFRSF10B RASSF2 TERF2IP IL18 NLRP3 HAVCR2 NFKBIA COPS8 EDN1 NR3C2 SPHK1 GREM1 TREM2 CALR HMGB1 EP300 RC3H2	down	*
MIR498_5P	0.0004191	0.0063809	0.4984931	-0.2804934	-1.521440	203	TRIM71 GCOM1 OSBPL11 LRRC8C TRPC3 BAG4 RTN3 DYRK1A KCNN3 VAPA TET2 MOB1B ZEB2 C12orf76 SEMA6D ATP2B1 MCTP1 PPP1R15B KLF6 FOXJ3 FAM122A TFRC PPP6R3 NOSTRIN DAB2 KLF7 ZBTB43 CAPZA2 TBC1D4 TLL1 NCOA1 CREBRF SYNPO2 TMTC1 NSMCE2 FERMT2 SKIL KLHL18 PCGF5 CREB1 LPCAT2 SNRK MEAF6 RHOQ YPEL2 CHORDC1 PHF3 NAB1 HBP1 GNA13 PDE4B ATAD2B MLANA POLR2M CREBBP B3GNT2 SKI GPR171 BMI1 CACNA2D3 IRF2 HIPK1 C5 CMPK1 EYA3 CD109 FAR1 PPIP5K2 PRTG	down	**
CSR_LATE_UP.V1_DN	0.0032228	0.0308473	0.4317077	-0.3009532	-1.521347	122	ACVRL1 SC5D HHEX IL1B CLEC3B INSIG1 BACH1 LONRF1 CDC42EP2 IDI1 HMGCR GAS6 STARD4 ADAM17 OLFML2A BTG2 MOB3C ANKRD29 DAAM2 DRAM1 VAMP5 PLCD1 DDX60L SFTPB PDE5A GYPC RASSF2 MSMO1 MME IRS2 SOD2 MRGPRF PAMR1 KIT FDFT1 LDLR C1orf52 C1orf115	down	*
GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN	0.0012057	0.0147041	0.4550599	-0.2891303	-1.521342	168	CXCL3 ARHGAP31 TMOD3 BCL2A1 IL1RN CCNL1 FBXO7 NFIX MAP3K8 CNTD1 AKT3 TFEC SRGN IL10 BIRC2 RMDN3 CLIC4 LY96 MGAT4A CDKN1A UBE2E2 GPR85 ATF3 HTT SPRYD7 PIAS1 FLT1 PODN MITF LRCH1 CPEB4 KCTD12 JUNB SKIL CD83 PHOSPHO2 CGGBP1 DEDD ZNF407 ACSL1 AGFG1 HIVEP2 TCF4 ATAD2B GTF2B MIER1 XKR8 ALDH1B1 TIAM1 DOCK10 TNFSF9 FEZ2 MIER3 CSF2RB ZNF800 DYNC1I2 PLEKHA2 CHAC2 EXOC6 FCF1 SLU7 HIVEP1 NCOA7 SLC25A28 RANBP2 WHAMM IL10RA TANK	down	*
GTF2A2_TARGET_GENES	0.0000048	0.0001502	0.6105269	-0.2620263	-1.521175	406	SNORD101 KCTD9 RNU1-1 WDR74 RADIL BAIAP2 SRSF7 RPL23AP53 EOGT ATF7IP2 SNHG5 ZBTB4 MALAT1 EIF1 CSRP1 EIF5 REV3L KLF6 SERPINB9 SRSF2 UBE2D3 TFRC TOB1-AS1 MCL1 NBPF12 SNHG1 CCNI ADARB1 SNAI1 PPT1 PTPN21 ZSWIM6 RNU11 PLEKHM3 RNU12 CEBPA CDKN1A NKIRAS1 ATF3 VIM ID2 LBH PTGER3 DUSP1 MFSD11 CARS2 HES1 CALM2 AFF1 BTG1 MYLIP TRAF3IP2-AS1 SGK1 TULP2 SOCS3 SEC14L1 SRSF3 NXF1 SNHG8 CYCS HSPA1B JUNB DNAJA1 EPC1 PPP1R15A IFRD1 PABPC4 DDX5 SELENBP1 HOMER1 NOL7 RNVU1-14 SLC3A2 FOS UBB CALM1 PXN-AS1 SRSF6 FOSB C19orf38 AZIN1 SAV1 ZNF596 EHD1 MRPL39 AP1G1 RNU2-63P KCTD10 MIA3 DYNC1LI1 SNORA57 TOB1 RNU5D-1 RGS2 GTF2B AMD1 JUND ZNF143 EGFL7 VGF RNU5B-1 IER5 RNU4ATAC HSP90AA1 USPL1 ACTB BRWD1 PCBP1-AS1 GLUL CHCHD7 RNU5F-1 TNFSF9 SFPQ EIF4A2 ATF4 PIEZO1 PIM3 HERPUD1 EGR1 PLAG1 ZBTB8OS FUS ING1 FTL HP1BP3 ZFP36 COX20 DNAJB4 CALR HMGN2 DNAJB1 SNHG9	down	***
GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0030170	0.0292824	0.4317077	-0.3003688	-1.520279	138	NUP54 BACH1 GTF2E2 DENND2C TRIB1 CCNL1 RBM7 SDE2 CSRP1 HSPB1 KLF6 CD93 FAM76A MAFG UBQLN1 DPH3 CXCL2 USP44 MIR24-2 DEGS1 MIR17HG CNOT6L TAF13 BTG1 CAPN11 PLK3 TMEM251 TMEM167B TNFRSF10B PTP4A1 PHF19 MAGOH ZBTB25 TOB2 MEX3C SCPEP1 KPNA4 ADORA2A MAFK CAMSAP2 ATF4 DNAJA2 BHLHE41 CLEC4E PIP5KL1	down	*
GO_CARDIAC_VENTRICLE_DEVELOPMENT	0.0058127	0.0477673	0.4070179	-0.3052790	-1.520094	106	SMAD6 FOXF1 CCM2L TBX3 ENG CITED2 BMPR2 TGFBR3 TGFBR2 SCN5A HEG1 PDE2A LUZP1 GATA3 FOXC2 TNNC1 ID2 SMAD7 ZMPSTE24 TBX5 HES1 MIR17HG TGFB2 RBPJ NOTCH1 WNT11 SAV1 TGFB1 MYOCD LTBP1 RXRA FKBP1A	down	*
GO_TEMPERATURE_HOMEOSTASIS	0.0016079	0.0181497	0.4550599	-0.2956580	-1.519841	145	FFAR4 EPAS1 IL1A NOVA2 EDNRB IL1B FABP4 TRPV2 CAV1 CD36 ADAM17 ADIPOR1 ABHD6 ADRB1 RB1 ADRB2 IL18R1 FOXC2 FABP5 PRDM16 FOXO1 ZNF423 ARNTL NPR3 PER2 TLR4 PTGER3 ADIPOR2	down	*
GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN	0.0026135	0.0262135	0.4317077	0.3362131	1.519680	170	BDH1 FANCI PDCD2L GGCT SORD CDK4 TRIB3 SPINT2 GLB1L2 XPOT ZWINT RUVBL2 DNPH1 NLE1 TP53BP1 ZNF485 POLD2 RBM28 SLC37A3 FAM162A MAD2L1 FNTB BLM UCK2 GOT2 SMG9 MCAT DGAT2 MRPL17 GNPNAT1 FEN1 FADD OARD1 POLR2H SNRNP25 VBP1 SMG5 COA3 DNAJA3 OSBPL3 RAD51D SPTSSA DPH2 MLEC SPAG1 NIF3L1 LIMA1 ORMDL2 AAAS RRP9 POP7 MCM5 C1orf109 RCC1 VDAC1 ATOX1 ARHGAP11A TARBP2 PAICS RRS1 MRPS26 PPP1R14B BRIX1 FTSJ3 TMCO6	up	*
GSE21063_WT_VS_NFATC1_KO_3H_ANTI_IGM_STIM_BCELL_DN	0.0011996	0.0146509	0.4550599	-0.2868106	-1.519514	173	ARHGAP31 CD52 ARRDC4 LPL LY86 SAMHD1 ALAS1 PILRA DNASE1L3 NAAA CLEC7A IFI30 SERPINB9 TFEC TXN CASP1 DRAM1 VASP STX3 RMDN3 PLBD1 ABCC4 ITGAX HOPX AXL GCA INSL6 HSDL2 USP25 INPP5B HK3 ELP5 IRF8 CST7 CD164 CD74 SMPDL3B ADPRM CD1D FPR2 GNB4 SOD2 STK40 PLAA PCCA IL18RAP ALDH1B1 SEMA4A EDN1 DOCK10 KLRK1 THEMIS2	down	*
GSE10325_MYELOID_VS_LUPUS_MYELOID_DN	0.0014412	0.0167097	0.4550599	-0.2865023	-1.519464	182	KMO AQP9 QKI FLVCR2 ZCCHC2 SLC39A8 MARCO IL1RN LAMP1 EPB41L3 IGSF6 ADAM17 GM2A ZNF410 HLX LAIR1 SLC25A37 TNS1 TFEC TXN ATP10A ADO KLF9 VRK2 CTSD ATG7 GMPR CDS2 CTBS PLEK PEF1 PAFAH1B1 HESX1 PHACTR2 RAB8B OASL GABPA ACSL1 SIGLEC1 CALM1 PTP4A1 EMC7 MILR1 CRYZL1 DPM1 PIM1 ADPGK KYNU	down	*
GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN	0.0040285	0.0363839	0.4070179	0.3348240	1.519290	176	ADH1C CDC45 RAB3IP TTK ANLN ASPM PTTG1 CDC6 MCM2 PRC1 XDH PDE9A RANBP1 NUDT1 KIF23 MKI67 TOP2A POLD2 MCM7 MPHOSPH9 CDCA5 KLHDC4 LMNB1 SLC12A7 PFKP BLM DRC1 ASF1B CDK1 PPIC UCK2 BIRC5 ACP6 PSAT1 PDK1 SSX2IP EZH2 NRGN DNMT1 SSRP1 DTYMK GEMIN5 PKP4 CNDP2 CENPK SASS6 PSMB3 RPA1 MRPL41	up	*
GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN	0.0012091	0.0147313	0.4550599	-0.2855780	-1.518868	184	FBP1 CYP27A1 LY86 C8orf58 MSRA ALAS1 ELMO1 NCF2 TGFBR2 FAM49A PDE2A EDEM1 SLC44A2 ARSB GM2A CLEC7A LITAF BFAR TFEC TUBB6 CD37 SORBS3 PPT1 SPNS3 FUT7 TMBIM1 ITIH5 COTL1 PTPRC VIM TLR4 ELK3 WFS1 ZNF706 ARHGDIB NRROS RPS6KA2 SOCS3 APPL1 RGS18 MITF STAT4 SH3BP5 RAC2 BTD TREM1 PTGER2 CD34 CDK14 NKG7 DGKG SMPDL3B TESK2 TEC	down	*
BROWNE_HCMV_INFECTION_4HR_DN	0.0021838	0.0229798	0.4317077	0.3267365	1.518831	211	CCL19 CHEK2 UGT8 ZP3 SIX1 UMPS PMS2 GLB1L2 ZNF3 AVL9 SHC2 AP1G2 AURKA ODF2 POLD2 SETDB1 TOM1L1 EMG1 MORC2 NFYA XRCC1 RGS4 MNAT1 TFCP2 DYRK2 GTF2E1 METTL3 RALGPS1 ETFB ABCA4 ZNF623 PIAS3 SLC12A1 NMNAT2 GALK2 NINL PTGER1 ZNF239 SCN8A FZR1 LIN37 NOC2L TMEM186 DNMBP LTBR TMEM30B POLB ABCC10 RIN1 AP3M2 LRRC17 DDX23 ZNF749 KATNB1 ZNF274 PATZ1 B9D1 ADM ZNF195 SERPINI2 ZNF217 SOX12 MICU1 CDK5 SNUPN PARG TRIB2 ZNF205 RORC NDUFB7 RRS1 SLC1A7 NCAPH GEMIN2 ZNF629 CSTF1 MIOS CXorf40A SBF1 GSTT2	up	*
GO_PLATELET_ACTIVATION	0.0019759	0.0212456	0.4317077	-0.3009542	-1.518813	134	CLEC1B F2RL3 P2RY1 THBD TRPC3 FYN CD9 GAS6 PEAR1 SH2B3 CSRP1 HSPB1 SLC7A11 WNT3A PDGFA ARRB1 DGKE MPL SELP AXL TLR4 FCER1G PLEK GNAQ UBASH3B PIK3R5 VWF SRF METAP1 IL6 PIK3R1 PRKCE YWHAZ PLCG2 PRKCG MYL12A DGKG STXBP3 VAV3 TEC	down	*
GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN	0.0007543	0.0102098	0.4772708	-0.2856076	-1.518721	176	KMO AKAP5 CYP27A1 LMO2 TMOD3 ST3GAL6 NEDD9 HEG1 CASP9 CD36 STARD9 IFI30 CNTD1 CYB561A3 FOXP1 MS4A1 SLAIN2 PPM1K REST FAM49B ZBTB43 RNF139 PLEK HLA-DQA1 MTPN RBM39 HCST HECA SF3B1 KCTD12 DHX15 FYTTD1 RBM22 MOB1A CDK17 MBP ICAM2 BAZ2B PDE4B EMC4 ATAD2B BMP2K BLOC1S2 IQSEC1 CUL3 CEPT1 CYTH1 PAIP2 LDLR NABP1 LPAR6 GIMAP4	down	*
E2F1DP1_01	0.0028913	0.0282764	0.4317077	0.3296965	1.518672	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
E2F1DP2_01	0.0028913	0.0282764	0.4317077	0.3296965	1.518672	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
E2F4DP2_01	0.0028913	0.0282764	0.4317077	0.3296965	1.518672	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
E2F_02	0.0028913	0.0282764	0.4317077	0.3296965	1.518672	196	GRIA4 GABRB3 CDCA7 E2F8 NABP2 AP1S1 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A EFNA5 C19orf57 MCM8 CAND1 EPHB1 RANBP1 WDR62 PAQR4 AP4M1 SPTB CBX3 MCM7 CLSPN RRM2 PRKDC FANCD2 MCM3 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 CDK1 POLE2 GMNN E2F1 UNG EZH2 THAP8 DNMT1 ZNF687 ACBD6 FANCG HIRA POLD1 TYRO3 ATAD5 NR6A1 SASS6 HMGA1 MCM6 SNRPD1 TFAP4 SRSF1 GINS3 STK35 ATAD2 NUP62 MSH2 YBX2 ARHGAP11A KIAA0825 MXD3	up	*
GO_CHROMOSOME	0.0000000	0.0000003	0.7614608	0.2960946	1.518525	1222	HMGA2 SIM2 MNX1 PKHD1 TRIP13 ONECUT2 ONECUT1 HNF1A TP63 DDX11 FOXM1 HELLS FOXA3 HJURP STAG3L2 RUVBL1 CDC45 PARPBP MCM10 PAX9 ASCL5 TFAP2A CHEK2 BUB1B NUP107 HOXD8 NEK2 TRNP1 CCNB1 SOX2 CENPF TIMELESS POLQ HOXB6 ZFHX4 CPSF6 NPAS1 TSHZ2 THOC3 NDC80 PRIM2 PIF1 BRCA1 SPDEF CREB3L4 FOXD4 SIX4 FANK1 ZFHX2 TTK GINS1 CDCA2 CDK4 E2F8 FOXE1 L3MBTL1 NPAS2 POLE NABP2 IRX6 PLK1 NUF2 CDCA8 AURKB CENPA SIX1 EBF3 WDR70 TBX19 SOX9 E2F3 TFDP2 FIGNL1 RBBP8 UHRF1 MCM4 HOXB7 MCM2 GRHL3 SP5 MYBL2 XRCC2 ORC1 DTL DYNC1I1 HNF4G MCM8 ASXL3 MIS18A GINS4 RCCD1 NCAPD2 ZWINT CDT1 DCTN2 SPDL1 TOP3B RSPH1 RUVBL2 SDR16C5 SMARCD3 SMARCC1 SOX30 STAG3 CHAF1A FOXA1 MKI67 BOD1 TP53BP1 FOXJ1 KNTC1 RHNO1 BUB1 MSX2 AUNIP TOP2A CENPL AURKA EME1 CBX3 REC8 POLA2 SYCP2 ATR POLD2 TPR IRF3 SMARCAL1 KIF2C MCM7 MAD1L1 ZNF174 E2F2 MSX1 CENPW MMS22L CDCA5 PRKDC TRRAP WDHD1 CSRNP3 HOXC6 HELB SETDB1 FANCD2 MCM3 CHAF1B HORMAD1 SOX4 BRD9 EME2 MORC2 ZNHIT1 TOPBP1 CHEK1 ORC6 ACTL6A MAD2L1 NFYA SOX11 FBL CENPO CSRNP2 RAD51AP1 XRCC1 THAP10 HES6 SPC24 DSCC1 MGA EHF RAD18 HSF4 REPIN1 BLM GRHL2 PML HOXB5 TADA2A MEOX1 TFCP2 RECQL5 PARP1 PES1 INCENP KNSTRN NCAPG2 TERC NUSAP1 ETV7 CBX5 ASF1B PAK1 CDK1 CDK12 POLE2 RFWD3 CENPH BIRC5 ARPC1A PHF12 ZMIZ2 E2F1 TBX15 NCAPG PRRX2 STAT2 DNA2 POU5F1B FEN1 EZH2 SPAG5 THAP8 TRAPPC12 OARD1 TTI1 MTBP CBX1 MAD2L2 RECQL4 CENPP ARNT2 TEP1 IRF6 RANGAP1 TBX1 DNMT1 PELP1 TELO2 INTS7 ZGPAT OVOL3 FOXK1 TRIM24 TUBG1 DCLRE1C ALX4 SATB2 ADNP DVL3 MBD4 RAD9A KIF22 HIRA RAD51D HMGN3 MTA3 SALL4 SUDS3 SSRP1 C1orf131 CHTF18 NFATC4 CENPQ AKAP8L HDAC1 ESCO2 GINS2 ANP32E LIN37 LRWD1 OTX1 CHD5 KDM3B CDK13 POLD1 THRB NUP85 ESR1 ATAD5 ENC1 PARP9 SLX4 RAD50 NR6A1 CCDC137 ETV4 KDM3A ANKRD31 CENPK BAZ2A PROX1 KLHDC3 EP400 UBQLN4 SUPT16H STAG3L4 CENPV NFXL1 CKAP5 PPHLN1 BRD8 HNF1B CENPM TWIST1 HMGA1 RPA1 TFCP2L1 NOL6 MCM6 HOXA3 DNMT3A CHTF8 THOC5 WRNIP1 DYNC1LI2 ZNF446 CENPT MCM5 ZRANB3 TFAP4 NSD1 ADD3 HMCES NFE2 EXOSC5 ESRRA CREB3L2 ETV6 RCC1 PHC2 SMARCC2 GTPBP10 ESRRB ZNF580 MSH4 SUV39H2 LHX4 MCRS1 MSH2 SMARCA4 PRIM1 NFRKB GRHL1 BBX BANF1 MLXIP RTEL1 RFC5 STAT6 WDR4 INO80E RAD51 HLCS TNKS1BP1 BRMS1 ZWILCH SEC13 CHMP1A FOXD2 LLPH LBX2 PAXIP1 SOX12 CHMP2A CHD3 WDR76 HOXB2 MXD3 RBM19 SIRT6 SMC2 BCAS3 TONSL BCL6 XPC MAU2 CENPE TCF3 SRCAP SWI5 TP53 ZBTB32 NEIL1 LEMD2 APEX1 TAF4 NCAPD3 PWP1 RORC RAD1 SMARCB1 E2F7 RRS1 NAT10 MUC1 THAP3 HOXA6 CLASP1 ZFPM1 ASCL2 ACTR5 SS18L1	up	***
GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN	0.0018112	0.0197986	0.4550599	-0.2860526	-1.518320	180	RAB11FIP1 ZC3H12C PTPRE FIG4 LMO2 TXNL1 GFOD1 HEATR5B PLEKHA1 P2RY13 ZEB2 ATP2B1 RNF144B RNF125 PTX3 GPBP1L1 ASH2L MOB3C PPM1K FBXL3 CXCL2 PLEK MIR17HG AFF1 NRROS SERTAD2 ARHGAP17 GPBP1 PRKRA SLC25A25 PKNOX1 BCAR3 C2CD2 MTMR14 CELF1 FOXN2 GPR183 PTGER2 SUCNR1 TCP1 NDUFV2 GRSF1 ATG3 PPTC7 GSAP RSBN1L MIA3 CD86 KYNU KTI12 ARAP2 SETDB2 UBE2D1 MEGF9 RAB2B NRP2 EHD4 STARD13 DUSP6 CCDC112 ATF2 LIN52 MZT1 ANKS1A	down	*
GO_REGULATION_OF_INFLAMMATORY_RESPONSE	0.0000634	0.0013183	0.5384341	-0.2750032	-1.518176	275	FFAR4 GPR17 ACP5 IL17RB FOXF1 TEK EDNRB PPARG WFDC1 IL1B FABP4 CDH5 LPL CALCRL MYD88 CASP12 IL1RL1 IL23A DNASE1L3 PDE2A APOD ANXA1 MIR146A PLA2G7 ADA CLEC7A FOXP1 GATA3 SIRPA RB1 GRN CASP5 SLC7A2 IL10 BIRC2 MEFV CASP1 BST1 KLF4 CEBPA SOCS5 CCL3 NFKB1 NR1D2 PTPRC TLR4 PTGER3 FCER1G PER1 PTGIS HCK IL17D IL6 SOCS3 APPL1 PSMA1 ETS1 PTGER4 CCR7 OSM SUCNR1 CST7 BCL6B TREX1 PIK3AP1 SMPDL3B CD6 FPR2 NLRP6	down	**
GSE7852_TREG_VS_TCONV_UP	0.0018112	0.0197986	0.4550599	-0.2860031	-1.518056	180	SWAP70 DENND5A CLDND1 ARRDC4 LONRF1 BMPR2 RXFP1 C3orf70 LYRM4 MAP3K8 PAQR3 TMEM123 TFRC PIP5K1B YBX3 ST3GAL2 SOCS2 SOCS5 ITIH5 NFKB1 CYP20A1 SHE PLEKHB2 ELK3 B9D2 MATN2 MATK GNAQ N4BP1 UBASH3B NCKAP5 SACM1L SNX3 PRKRA CD80 PHTF2 KIF13A ELP5 GSTO1 CD83 IRF8 TNFRSF9 OGFRL1 ZBED5 YPEL2 PDCD1 CD81 NRN1 POLK CCR6 CALHM2 TIAM1 ITGAE	down	*
GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP	0.0052180	0.0441398	0.4070179	0.3392885	1.517812	157	SIM2 KRT5 FANCI PBK TTK COL7A1 TYMS CA12 EIF3B GUCA1B CEP55 ITGB4 POLA2 TMEM132A TPCN1 LIPE TRRAP ERAL1 BRD9 CHEK1 GEMIN4 RNF216 NCAPG2 HDGF TCF20 NEIL3 ZNF500 PIAS3 SPG7 ARHGAP32 COG2 CCDC51 TADA3 NSD1 POLR3E LHPP GOSR2 BCL9 MMP16 TSC2 ABCF3 ANAPC2 ERBB2 PNKP CENPE IDUA CDC25B NAT10 FAM222B TRPC4AP ERCC3 ACIN1 ADRA2B GRIP2 DAZAP1 KLK10 TEAD3 RUSC1 DSN1 CNKSR1	up	*
GSE14000_UNSTIM_VS_4H_LPS_DC_UP	0.0042268	0.0377893	0.4070179	0.3356972	1.517746	174	DEPTOR MSTO1 CCT6A SPDL1 TAMM41 GTPBP3 POC1A WIPI2 AIMP2 B4GALT7 OGFOD2 NAA40 DHRS13 DDX51 EXOSC2 MCAT FEN1 EFTUD2 SATB2 NADK2 SLC26A2 TACC3 ZNF544 NUDT16 CPSF4 POP7 UBXN6 PEX5 KDM4B THOC5 HAUS6 SNAP47 RAB3D GINS3 AATF TCHP ZSCAN16 SPSB3 SMARCA4 MLXIP POLR3B CLUAP1 RSAD1 GTF3C5 BCAS3 KDM5B NCAPD3 RRS1 NAT10 FTSJ3 C12orf10 ALKBH2 ZNF630 DCAF16 POLRMT PSTPIP1 MBTD1 SHQ1 SPHK2 BCL7A ATRIP ZNF77 SHB SLC7A6OS KCTD6 SWSAP1 HENMT1 EPS15L1 PRDM15 DEF6 ZBTB48 MPLKIP WDR12 SLC27A1 RFC3 CROT	up	*
GSE7852_TREG_VS_TCONV_FAT_UP	0.0014132	0.0164724	0.4550599	-0.2863295	-1.517701	181	ARHGAP31 SWAP70 PPARG LRRC8C TMEM170B MTMR10 STX11 ANXA1 EIF4A1 GM2A ZNF503 CYP4V2 KDSR ARRB1 SORBS1 NPNT ZCCHC24 TMBIM1 CDKN1A ATF3 HOPX M6PR DUSP1 GNAQ SNX3 ELF1 AREG ARL5B MITF IFNGR1 ENPP4 COBLL1 SERPINB6 ATP13A3 TNFRSF9 APH1B SNX9 YPEL2 IRF5 TGIF1 GALC PDCD1 DBNDD2 FAM98B GEM SESN1 IL18 ITPRIPL2 ARL14EP SAMSN1 EHD4 PIEZO1 RABGEF1 DMXL2 HERPUD1 JDP2	down	*
GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN	0.0013759	0.0162382	0.4550599	-0.2914301	-1.517411	161	CXCL3 IL17RB SWAP70 TSPAN4 DENND5A PPARG MYADM IL1RL1 SLC44A2 ENTPD1 PAQR3 PAG1 TRAF6 GPM6A EXOSC9 PTGIR AHNAK KLF11 SOCS2 NFKB1 CDKN1A DUSP11 SHE MATK GNAQ N4BP1 AFF1 RPL17 AREG IL6 APPL1 ARL5B SH3BP5 KCTD12 PTGER4 SKIL COBLL1 PIM1 LGALS3 CCR1 KAT2B SERINC3 RXRA BMP2K TPT1 FBXO30 ITGAE	down	*
GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP	0.0039066	0.0356221	0.4070179	0.3321018	1.517140	181	TTF2 TBRG4 KIF14 IFT27 GPI TRIB3 UMPS MIS18A GINS4 CISD1 MKI67 STAP2 EEF1E1 DCTPP1 PKMYT1 TADA2A ALDOA MNAT1 HDGF GOT2 STEAP1 RECQL4 EIF6 VBP1 UQCRFS1 TRIM24 CDC23 COA3 DNAJA3 PUS1 DHODH PSME2 MRPL11 TK1 MYBBP1A ASNS POLD1 JTB RAD50 TSTA3 POP7 GMPPA KPTN LSM7 NDUFS7 LSM4 TCERG1 PRIM1 SNRPD2 RFC5 BMS1 GADD45GIP1 NDUFA8 DNPEP CPOX SLC12A2 SMC2 POP4 SF3B2 PWP1 MRPL48 DNM1L COX17 CALU RANGRF GEMIN2 MRPL12 PRPF19 CLPP TOMM40 NCKIPSD CS NIT2 RMI1 REEP4 CALM3 BNIP1 COX6A1	up	*
GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN	0.0012444	0.0150470	0.4550599	-0.2883064	-1.517007	168	SLPI PNPLA6 ST8SIA6 KLF13 HSD17B11 PDE1B BACH1 MEF2A TMX4 KCNAB1 CNST RAB33B FOXP1 CD37 ITPRIP RAB12 TCP11L2 STK17B LBH RAP1GDS1 KREMEN1 FAM102B HECA SF3B1 ETV3 MITF VPS26A CCR7 PRKCE FRYL IP6K1 RNF146 TTBK2 SPOP ZRANB1 BAZ2B HBP1 FCGRT TAGLN LAT TRAPPC8 BRWD1 CREBBP TTC19 SNX15 PAIP2 RHOT1 C1orf52 SMAD4 HNRNPH1 CBX7	down	*
GO_REGULATION_OF_ANATOMICAL_STRUCTURE_MORPHOGENESIS	0.0000000	0.0000006	0.7477397	-0.2403728	-1.516543	889	TNR LIMS2 ANGPT4 DAB1 SEMA6B AJAP1 SEMA3G SEMA6A TMEM100 ACVRL1 WTIP IL1A SASH1 HMOX1 TEK DLC1 FGD5 PPARG HHEX GATA2 IL1B TIE1 DCSTAMP WNT4 P2RY1 EMP2 RDX DPYSL2 RAPGEF2 BMPER RAMP2 PID1 BMP2 TRPV2 CDH5 ENG BDNF FYN SHANK3 CD44 ECSCR CORO1C MYADM NEDD4L BAIAP2 CITED2 BMPR2 GTF2I CDC42EP2 TBXA2R C5AR1 FGF10 CDC42 MIR27B NEDD9 IL1RN PSMD5 EPB41L3 TGFBR2 HSPG2 FGR RHOA ZEB2 SEMA6D CD36 ANXA1 TBX2 MIR146A MMRN2 PTPRM SEMA3B ADA TTL FOXA2 HECW2 WNT2B RAP1A PLXNA2 ITGA5 HSPB1 FZD4 FOXP1 GATA3 PPP3CA ZMYM6 PLXNA4 RGCC ISLR2 NFE2L2 NDEL1 GRN CRK SFRP1 AKT3 SPRY2 WNT3A ITSN2 PDGFA FOXC2 NODAL CST3 ATP10A RHOB LRP4 GPR4 IL10 AGO4 ROCK2 NRARP PTPRO LIMS1 ZSWIM6 TRIM46 TNFSF12 TSPAN12 KLF4 ROCK1 DAB2 PARVB THBS1 ADAMTS9 CLDN5 MPL SEC24B TMBIM1 FMNL3 CCL3 PDE3B ITGAX ARC MIR24-2 RECK SS18L2 CD53 WASF3 PIK3C2A ZMPSTE24 PINK1 TBX5 PRICKLE2 PAFAH1B1 PTGIS RUFY3 HES1 ANXA3 ACTR2 TGFB2 HEXB HCK SRF BTG1 KANK1 RBPJ FMNL2 CNTF FLT1 IL6 CD160 DDHD1 PSEN1 MAGI2 PSMA1 VAT1 NOTCH1 RHOBTB2 LIMD1 ETS1 RAC2 TYROBP RHOG JAK1 RHOJ PALM FERMT2 SKIL IFRD1 NPR1 RC3H1 RTN4R ZNRF3 TRAK2 PALMD CD34 POGLUT1 RHOQ RRAS KLF2 MBP PSMD12 EHD2 SRSF6 WNT11 BTBD7 TGFB1 EPB42 EHD1 PARD6A DDHD2 ISM1 ZRANB1 HECW1 MIR23A PIM1 CLASP2 GATA6 GNA13 MACF1 PLAA ADAM10 IST1 RXRA UNC13D ICAM1 FGF2 PDLIM5 ARPC2 VASH1 WDR1 EPN2 ARRB2 OSR1 SEMA4A RTN4 CDC42EP3 TIAM1 CXCR4 EPHA4 ARHGAP18 SP100 BRWD1 PSME4 EPHA2 RND1 ULK2 PARVA GLUL SIN3A RET RAPGEF3 KIT EDN1 FOXJ2 PTEN	down	***
GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP	0.0009532	0.0122549	0.4772708	-0.2888730	-1.516089	167	SEMA3G SIK1 HSD17B11 SAMHD1 AKAP7 ELF2 YPEL5 MSRA RPL23AP53 FRAT1 ATF7IP2 TMX4 TXNIP ANXA1 DPEP2 LAIR1 SPTBN1 PDE4D MOAP1 TLE4 GPA33 ITM2B MGAT4A ARL4A PLCD1 MAPRE2 TBC1D5 AQP3 HECA CD48 JUN AK1 BAG5 NUDT15 UVRAG TSPYL1 FOS KLF2 PTP4A1 MMP15 IRS2 FCGRT TOB1 KANSL2 BNIP3L RLF IQSEC1 ZBTB25 NLRP3 ACACB S100A4 OSER1 RBM48 DAZAP2 NR3C2 PPP1CB ARHGEF18 ITGB1 FAM8A1 ZFP36 DNAJB1 PIAS2 LDB3	down	*
GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN	0.0027094	0.0268869	0.4317077	0.3334038	1.515734	179	TRIP13 GPT2 CCNB1 TBRG4 PHGDH ACAD9 ALDH18A1 ESPL1 SPINT2 ORC1 DTL LIG3 C19orf48 CISD1 GFPT1 QTRT1 PCCB CCT5 COASY FSD1 NSUN2 WDR73 SLC25A39 HSPBP1 DDX56 THOP1 SNX4 ARPC1A TRAP1 POLR1C POFUT1 DNAJA3 LMNB2 SSRP1 ZNF239 MFSD2A GINS2 XPR1 SND1 MAGOHB CCDC137 PFAS VPS25 ORMDL2 CENPM KIAA0100 FAM136A CREB3L2 SLC1A5 SUV39H2 CISD3 DDX54 POLR3B ATOX1 CDK5 RBM19 SMC2 ZBTB32 PCBD1 SFXN4 RRS1 TRUB2 ALKBH2 RNF14 SRM TOMM40 TIMM10 TLCD1 URB2 NETO2 LRP8 RBM8A CCDC86	up	*
MIR4295	0.0000372	0.0008437	0.5573322	-0.2652122	-1.515616	338	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 LRP4 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	***
GO_TISSUE_REMODELING	0.0018531	0.0201623	0.4550599	-0.2943722	-1.515530	143	EPAS1 ACP5 ACVRL1 IL1A ACE SNX10 DCSTAMP LIPA CAV1 BMPR2 S1PR1 FGF10 IL23A ANXA1 PPP3CA ADRB2 TRAF6 SFRP1 TFRC FOXC2 CST3 ROCK2 ROCK1 TPP1 TMBIM1 AXL UBASH3B PTH1R PDK4 RBPJ IL6 MITF RAC2	down	*
GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY	0.0001627	0.0028863	0.5188481	-0.2726382	-1.515450	271	SMAD6 TMEM100 ACVRL1 SOSTDC1 SFRP4 GREM2 BMPER BMP2 CDH5 ENG FOLR1 CAV1 CITED2 BMPR2 RBM14 FGF10 TGFBR3 CBL TGFBR2 RHOA TMPRSS6 LTBP4 ADAM17 NLK CAV2 SFRP1 SPTBN1 ZFYVE16 ZEB1 UBE2D3 NODAL PRDM16 SDCBP NPNT ZNF423 DAB2 THBS1 CLDN5 VIM SMAD7 INHBA VEPH1 HES1 HTRA4 MIR17HG TGFB2 NRROS RBPJ ADAMTSL2 APPL1 MAGI2 JUN NOTCH1 LTBP2 BMP3 FERMT2 SKIL DDX5 CREB1 FSTL3 FOS UBB TGFB1 PARD6A ZFYVE9 TGFB1I1 LRRC32 MYOCD TOB1 LTBP1 SMAD2 LDLRAD4 FKBP1A ARRB2 CDKN1C DACT2 UBE2D1 CREBBP ING2 ETV2 SKI LTBP3 SMAD4 SKOR1 ARHGEF18 ACVR1C EGR1 GREM1 DKK3 LNPEP ZYX CD109 NOG SNW1 CTDSPL2	down	**
GO_REGULATION_OF_LYMPHOCYTE_ACTIVATION	0.0000185	0.0004717	0.5756103	-0.2606973	-1.515447	378	SIRPB1 CD55 SPN IL1B MNDA FYN CAV1 FGF10 PRKAR1A CDC42 GAS6 LAMP1 CD22 TGFBR2 IL23A FGR RHOA ANXA1 CLCF1 FBXO7 CD5 ADA CLEC7A MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 SFRP1 WNT3A ZEB1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 BST1 SLC46A2 CLECL1 SOCS5 MPL FAM49B CDKN1A PTPRC AXL ID2 TLR4 IGFBP2 SFTPD SMAD7 INHBA IL7R CYP26B1 HES1 MIR17HG GNRH1 NCKAP1L CD80 IL6 CD160 PDE5A RAC2 TYROBP CCR7 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 DOCK8 AP3B1 TBX21 ZNF683 TIGIT PELI1 TNFSF13 RUNX3 TREX1 CD74 CR1 TGFB1 VAV3 AP1G1 CD1D ZBTB1 CD6 LRRC32 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23	down	***
GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN	0.0018380	0.0200406	0.4550599	-0.2854667	-1.515209	180	MIR22HG CLDND1 STX11 RFTN1 TMX4 ANXA1 UBL3 TTYH2 STOM SRGN BTG3 TXN CD58 EVI2B AGO4 LIMS1 COTL1 HOPX EPS15 ALOX5AP LACC1 RNF149 PHTF2 KLRB1 PHACTR2 AQP3 SH3BP5 GLIPR1 CDK2AP2 OGFRL1 TBX21 TIGIT CD74 AKIRIN2 PEA15 DUSP5 ATXN1 LGALS3 CCR6 TRAC SLC35D2 CALHM2 CDC42EP3 ARHGAP18 S100A4 CTSC KIF1B RORA NABP1 IQGAP1 SPOPL MIS18BP1 PIEZO1 SH3BGRL3 ITGB1 MTSS1 ATP2B4 CD226 MYO1F CBLL1 ADAM19 PLXNC1 MFHAS1 CPPED1 GZMK IL10RA CAPG ZC2HC1A TMEM64 GZMA IQGAP2	down	*
AGCATTA_MIR155	0.0030892	0.0298249	0.4317077	-0.3015345	-1.515039	118	WEE1 SGK3 BACH1 QKI S1PR1 KCNN3 ATP2B1 NFIX PICALM CAMTA1 SPI1 UBE2D3 TLE4 SDCBP GPR85 N4BP1 RAB6A CREBRF ARL5B ETS1 CNTN4 FBXO11 SP3 YWHAZ CELF2 HIVEP2 TSHZ3 PKIA PDE12 TSPAN14 HBP1 MEIS1 TAB2 G3BP2 SSH2 BCAT1 SKI	down	*
GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN	0.0024201	0.0248011	0.4317077	-0.2898361	-1.514818	162	GIMAP8 CD44 TMOD3 AKAP7 IDI1 HMGCR TNFRSF8 STARD4 LMNA NAAA KLF10 CAV2 GPBAR1 TUBB6 RHOB FBXL5 ARRB1 DUSP3 SCP2 ZCCHC24 KLF11 ARNTL IRAK2 CYP20A1 ID2 MIR24-2 CCND2 PLEKHB2 PLEK ZMPSTE24 ARL4A C16orf54 SPIN1 SGK1 C2CD2 ARL5B PLK3 DNAJA1 GRB2 CAP1 RALB PTP4A1 TTBK2 ZFAND6 EHD1 GALC PDCD1 ATXN1 DOK2 POLK CYB5R4 ARHGAP18 ARL14EP OSER1	down	*
WELCSH_BRCA1_TARGETS_UP	0.0007897	0.0105828	0.4772708	-0.2848498	-1.514541	175	PTCRA CAT RDX LIPA INPP5K CITED2 GTF2I PRKAR1A NR3C1 CD9 ANXA1 PBX3 PICALM ANXA5 GATA3 UBE2D3 KRT4 SRSF5 LIMS1 YBX3 CDKN1A ID2 PPP2R5C TM9SF2 ADD1 RABGGTB HEXB RAB6A PRCP VAMP3 ID4 COPS2 PPP6C SRSF3 JAK1 CREB1 RAB8A RRAS AGPS MYL12A SERPINB1 GNAI1 NFYC FCGRT ZNF267 SERINC3	down	*
MIR4498	0.0026485	0.0264068	0.4317077	0.3266508	1.514467	205	SLC9A3 PPM1H PCDHGA10 CPLX2 PKP2 ARMC3 PCDHGA9 JPH3 PCDHGA5 PCDHGA7 SDK2 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 CUEDC1 PCDHGB4 PCDHGA11 PCDHGA8 TNC OSBP2 TMEM41A PAQR4 PCDHGA12 PCDHGC5 PCDHGC4 PCDHGA4 PCDHGB7 PCDHGA3 PLXNA1 PROM2 CLIP3 EEFSEC PML TMEM178B TTYH3 ZNF346 PPIL2 IGFBP5 PACS1 FBXO41 LARP1 GPRIN1 RAB6B PCDHGA2 ARNT2 ACVR1B SRD5A1	up	*
MIR454_3P	0.0000296	0.0006971	0.5756103	-0.2607562	-1.514452	371	WEE1 EREG DLC1 PPARG SECISBP2L CPEB2 GPR65 DPYSL2 INSIG1 TRPC3 TMEM170B FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 MCTP1 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 IKZF5 BTG1 TMEM9B CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 ZNF555 CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 PHF3 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 NPTN PLAA CLCN6 SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 CHMP3 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	***
KEGG_MAPK_SIGNALING_PATHWAY	0.0003011	0.0049050	0.4984931	-0.2784441	-1.514345	222	IL1A IL1B RAPGEF2 PLA2G10 BDNF FGF10 CDC42 MKNK1 TGFBR2 CACNA2D2 RAP1A RASGRP4 MAP3K8 HSPB1 NLK PPP3CA NR4A1 TRAF6 LAMTOR3 CRK AKT3 MAPK8IP1 PDGFA PPP3CC MAP2K3 ARRB1 DUSP3 NFKB1 DUSP1 TGFB2 SRF RPS6KA2 JUN RAC2 MAP4K4 HSPA1B DUSP8 GRB2 RPS6KA1 PRKACA FGFR4 FOS RRAS PRKCG MAPK8 FLNC TGFB1 DUSP5 MAP3K2 PPP3R1 JUND HSPA2 FGF2 ARRB2 TAB2 HSPA8 MAP3K4 STK4 PAK2 DUSP7 FGFR1 ATF4 CACNA2D3 CHP1 DUSP6 ATF2 MAPK1	down	**
GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP	0.0026198	0.0262215	0.4317077	0.3354912	1.514273	167	FANCI ZNF280B NUDCD3 ALDOC GINS4 NCAPD2 MYL6B DLG1 RPAP1 FRS2 CCDC77 FBF1 TMEM177 SNHG11 SLC45A1 ACSF2 XRCC1 TBC1D8 MGA ZNF605 COQ9 FAHD2A CCT3 KCTD13 SNAPC1 PRPF6 MAD2L2 ZKSCAN5 SMG5 FANCF NFS1 COPS7B SLC22A5 KRI1 LRWD1 NAT9 PTER VPS25 IARS2 TUBG2 ASCC1 BAD UBE2V2 BLCAP MYH3 RCN3 MANBAL PCBD2 GTPBP2 ATOX1 RELL2 POLR1A PRPF3 ARMC10 DTD2 PIGQ ACAD8 MIR600HG C12orf10	up	*
GO_PHAGOCYTOSIS	0.0001374	0.0025096	0.5188481	-0.2724026	-1.514141	270	SIRPB1 CD300LF FCN1 PECAM1 PPARG FCN3 GATA2 IL1B FYN CORO1C BAIAP2 MYD88 ELMO1 CDC42 MARCO NCF2 GAS6 SLC11A1 PEAR1 FGR CD36 ANXA1 IGKV2-28 RAP1A CLEC7A PTX3 SIRPA CD93 CRK RAB14 MSR1 THBS1 PTPRC AXL TLR4 CD302 ACTR3 SFTPD FCER1G LYAR C4BPB ANXA3 ACTR2 HCK NCKAP1L SNX3 IGLV2-11 MYO1C WASF2 IL2RB APPL1 RAB31 RAC2 TYROBP RHOG RAPGEF1 PIK3R1 IRF8 PRKCE GRB2 IGKV3-20 PLCG2 ATG3 PRKCG TREX1 BIN2 VAV3 JMJD6 FPR2 IGHV3-23 IGKV1D-39 SYT11 UNC13D ARPC2 XKR8 RAB5A HSP90AA1 ACTB ICAM3 ADORA2A CD3G ARPC5 PTEN ANXA11 LDLR ANO6 SPHK1 ABI1 CYBA IGKV2-30 MAPK1 ITGAL ITGB1 TREM2	down	**
WANG_CISPLATIN_RESPONSE_AND_XPC_DN	0.0009797	0.0125140	0.4550599	-0.2813391	-1.514031	197	SLC31A2 GLIPR2 RAMP2 CDC42EP2 EIF4A1 CHMP1B KLF10 HIPK3 PRSS12 HLX STOM ARHGEF2 HERC3 FLI1 CYBRD1 SDCBP YBX3 SLC12A4 MYO1B CDKN1A KCNMB1 UBE2B TAF9 SMAD7 EFR3A MMP19 BTG1 ELF1 CDC40 EBAG9 JUN CELF1 RAC2 IFNGR1 WTAP FERMT2 TNFRSF10B ITGA11 DEDD GRSF1 RRAS TGIF1 VAMP4 CTNNAL1 GNAI1 PDLIM1 HBP1 CNTNAP1 PHF11 SESN1 ZNF143 NT5C2 ATP9B UBE2D1 SP100 CUL3 PRKG1 NRG1 TLK1 RNH1 DNAJA2 SLC35A1 CYBA KALRN FADS3 HAS2 CSNK1G3 PTGS1	down	*
PECE_MAMMARY_STEM_CELL_DN	0.0034630	0.0326826	0.4317077	-0.2994093	-1.513542	122	SRSF7 IDI1 EPB41L3 ACER3 CCNL1 TXNIP UBL3 ARHGEF2 TCF7L2 SNED1 MAP1LC3B PLBD1 SCAF4 EPS15 WASF3 TM9SF2 DEGS1 NSMAF DESI2 CTSZ GLUD1 JAK1 ZCCHC9 RNF146 CALM1 ZBTB1 TMEM230 PCM1 CDC16 SEC63 CUL3 JMJD1C RAB2B SFPQ CNOT8 PURB ITGB1 EBF1 HEY1 XRN2 NKTR RPP14 ANKH EMP1 DENND4C PUM2 REXO2 PNISR BTBD19 SQLE	down	*
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP	0.0045235	0.0397077	0.4070179	0.3329960	1.513486	178	TRIP13 RUVBL1 RPGRIP1L TIMELESS SCN3A GINS1 STIL MYBL2 PRC1 ORC1 COPB2 MIS18A ZWINT MYL6B PCCB CCT5 CBX3 KIF2C CD2AP RNFT2 TOPBP1 ORC6 MAD2L1 DET1 PON2 TNFRSF21 UCK2 C1orf112 AAGAB GMNN GOT2 FEN1 CBX1 FOCAD PA2G4 CHCHD3 VIPAS39 NINL MRPL11 TCEA1 SPAG1 SND1 CCT7 CDC20 MCM6 TDP1 TCERG1 CFH MSH2 TM7SF3 CCNA2 PRR11 DENR ABHD10 TPGS2 MICU1 NUBPL SMC2 FAIM GMPR2 CENPE SCN9A PAICS SIGMAR1	up	*
GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN	0.0013945	0.0163735	0.4550599	-0.2849064	-1.513397	179	PECAM1 PPARG LTA4H DCSTAMP P2RY1 STXBP6 CCDC88A CLYBL ZCCHC2 ESAM PAFAH1B2 TGFBR3 TXNIP ANXA1 ARHGAP10 CLCF1 CHMP1B ZBTB21 ZNF697 TFRC ATP6V1H ZADH2 SOCS5 CLIC4 RBMS1 DUSP11 MATK PRICKLE2 ZNF706 PTGIS LMBRD1 ARL6IP5 PPIL4 S1PR4 SLC25A25 ESD PLEKHA3 NXF1 PPA2 CNNM2 AK1 GYPC	down	*
GO_ENTRY_INTO_HOST	0.0036087	0.0336605	0.4317077	-0.3028578	-1.513363	107	FCN1 GPR15 CD55 FCN3 SLC10A1 CAV1 GAS6 LAMP1 CBL ITGA5 ANPEP CAV2 PTX3 TFRC AXL EPS15 KPNA3 SNX3 CD80 HSPA1B GRB2 UVRAG CD74 CR1 NUP153 CD86 CD81 ICAM1 SELPLG EXOC2 CXCR4 EPHA2 ITCH LDLR	down	*
ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN	0.0058169	0.0477864	0.4070179	-0.3092840	-1.512781	98	SIDT2 TRPV2 LYL1 LMO2 KLF6 ARHGEF2 ADAMTSL4 MCL1 STAT5A EPOR ST3GAL2 CTSD RIT1 PTPRC ARL4A CMTM6 CREM SLCO2B1 AQP3 SEC14L1 RAC2 JUNB RHOG SELENBP1 CAP1 MCAM CBFA2T3 PIM1 FAXDC2 KYNU CALB1 TNFAIP8 ESYT1 BCAM SAMSN1 ARFGAP3	down	*
GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_UP	0.0059416	0.0485930	0.4070179	0.3471832	1.512733	125	TF PTPRR STC2 HOXB7 PLS1 ACY1 TDRKH TOP3B MYBPC2 KIF2C B3GNTL1 RIPK4 CDC42EP1 GPR135 KHK PTGDR2 RGS4 C7orf26 PTPN3 ZNF512B IGFBP5 NAV2 IGSF3 ZKSCAN5 LGR5 TELO2 TUBG1 MSRB2 EPB41L4B ERBB3 ZNF428 NRXN2 UBXN6 TFCP2L1 METTL2B LPCAT4 DHX8 KPTN DUS2 MYH13 YBX2 PCSK5 PRSS22 MAP3K9 ST20 TACR1 BPNT1 BFSP2 SETD5 WDR55 RNF126	up	*
GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_DN	0.0045399	0.0397970	0.4070179	0.3345557	1.512585	174	DEPTOR NUP107 UBE2T PGM2L1 SIX4 POLE ALDH18A1 PMS2 MRPS35 CLPTM1L TTLL4 CEP55 AUNIP RAD54L YEATS2 ORC6 NFYA GAS8 RAD51AP1 RPAP2 BRIP1 CAD PPP5C GLE1 KCNE3 SLC25A13 ANKRD26 LIPT2 RNF150 ABHD4 PLEKHG3 MRPL52 SPTSSA DTYMK GALNT3 PSMD2 NUP85 TIMM13 IARS2 ZCCHC17 RRP9 CACNG8 TDP1 RHOBTB1 SLC1A5 SH3PXD2B CEP152 FARSA SUV39H2 JAKMIP3 CCNA2 HLCS SCOC SNX8 PARP2 MFSD3 CLNS1A FAM120A DFFB NELFB EIF2B1 ADSL IL1RL2 MRPL2 SNHG17 TIMM10 RCC2 GCSH DGKZ IMP3 ZSWIM7 PARP16 SRSF9 PRKAB2 ZNF664 PPM1G BUB3 TRIM28 JKAMP DAGLB DDX31 DVL2 TIMM23 DRG2 DPY30 NAA38 SSNA1 SENP5 GTF2A2 TAZ	up	*
GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_UP	0.0013454	0.0160042	0.4550599	-0.2911836	-1.512484	160	FCN1 IL1B MIR22HG SIK1 LDB2 YPEL5 TRIB1 IER2 ANXA1 DNAJC3 ASAH1 CLEC7A RNF125 TCF7L2 FBXL5 ITPRIP KLF4 COQ10B KLF11 ID2 SNORA28 DUSP1 RNF139 IL7R C16orf54 VCPKMT HCK SLC25A33 TMEM9B SGK1 JUN SNX29 RAPGEF1 ATXN1L SKIL CD83 GRASP KLF2 PTP4A1 ZNF669 BIN2 NAP1L5 GSAP ABHD13 ZNF844 IRS2 GABARAPL1 KANSL2 RGS2	down	*
GO_ADENYL_NUCLEOTIDE_BINDING	0.0000000	0.0000002	0.7749390	0.2944670	1.512403	1297	KIF1A ATP10B CPS1 KIF12 STYK1 TRIP13 HKDC1 ABCA13 DDX11 ENTPD2 ABCC2 HELLS EPHB3 KIF20A DDX12P RUVBL1 AK4 DNAH2 CHEK2 BUB1B SLFN13 MYO3B PPIP5K1 NEK2 XYLB FRK POLQ UBE2T PBK KIF18B TTF2 GUCY2C PIF1 NMNAT3 IP6K3 STK36 TTK CDK4 BRSK1 SLC27A2 KIF14 UBE2Z ABCA12 GMPS STK31 FLAD1 PLK1 AURKB ACAD9 ALDH18A1 PAK6 CDC6 WNK2 TRIB3 FIGNL1 MCM4 PRKCA MCM2 RAD54B DNAH3 PMS2 NWD1 XRCC2 ORC1 AACS CCT6A MCM8 PIP4K2C LIG3 MAP2K6 SGK2 SRPK1 KIF27 INSRR EPHB1 P2RX2 DNAH14 MPPED2 CCT2 AGK AK8 NME1 IKBKE AARS2 TTLL4 RUVBL2 MELK DYRK1B KIF23 MKI67 CUL9 SLFN5 HLTF KIF15 PCCB HS3ST5 MAP3K13 KIF3B BUB1 TOP2A CCT5 AURKA MYO10 ATR LARS2 SMARCAL1 KIF2C MCM7 COASY ABCC5 TTLL12 PRKDC RHOBTB3 HELB RAD54L PKM SBK1 EIF2AK1 PHKG2 KIF11 PASK MCM3 PEX6 MCCC2 TARS2 CHD6 EGFR DNAH8 LIG1 SARS2 RIPK4 MORC2 ABCB6 CHEK1 NEK11 ASS1 ACSF2 AHCY KIF3C EPHA10 PFKP ABCB9 HSP90AB2P MST1R KCNJ11 KHK AKT2 CNGB1 PKMYT1 DNAH11 BRIP1 DDR1 CAD BLM PPP5C ATAD3C ERCC2 TRPV4 HSPBP1 MYO1A TRIT1 RECQL5 DYRK2 DDX56 MARK1 TNIK IKBKB DCLK1 TTBK1 CBWD6 FASTK NSF DDX51 HARS2 PAK1 LRGUK CDK1 CDK12 DNAH6 EPHA1 KIF5A UCK2 MERTK STK32A CCT3 ATP2A1 TTLL9 TNK2 NAV2 DHX37 TRAP1 ABCC11 SYN3 MAP3K10 KIF19 DNA2 ACTR3C KIF2A DHX33 ACSBG2 KIF7 ITPKA KSR2 PDK1 NEK5 ACTR3B MYO5B AK7 ATAD3A DNAH5 PRKAA2 ABCA4 UCKL1 PSMC4 RTCB RECQL4 MAST1 ACVR1B STK11 TEP1 GAL3ST4 ULK1 DHX34 HSPA4L NMNAT2 MYO19 ACBD6 PARS2 MOV10 ANKK1 ILF2 CDK3 ATP7B DCAKD NEK10 NADK2 SPG7 DNAH7 DHX40 GALK2 TRMU MTOR GSS DNAJA3 ATP9A AARSD1 LONP1 TRIO KIF22 MAPK13 RAD51D EPHB2 ACBD4 UBE2Q1 TK1 DTYMK CHTF18 CNGA4 SCN8A KIF21A CSNK1G1 LMTK2 SLC22A5 HSP90B2P MAPK10 TSSK3 KIF20B NDUFA13 ASNS GK5 CHD5 CDK13 TTLL10 TWF1 ACSL6 SIL1 TYRO3 ATAD5 MAT1A ATP13A1 NADSYN1 CCT7 CDC7 IP6K2 YARS2 RAD50 ABCC10 TNK1 EP400 ACBD5 PFAS UBE2O ABCC9 ENTPD8 DGKA IARS2 ERBB3 POPDC2 TTLL3 ACLY ENTPD3 ABCC3 ABCA7 FANCM MCM6 MYO5C CKMT2 WRNIP1 DYNC1LI2 KIF21B CDC42BPG SRPK2 DHX8 MCM5 NMNAT1 ACOT11 ZRANB3 DDX23 DYNC2H1 NEK4 LANCL2 SCYL3 ADCK1 PIP5K1A MYH7B PFKFB4 LRRK1 TTLL6 IGHMBP2 MYH3 MAB21L1 MUSK ABCD4 PALM3 PRKD2 STK39 PI4KA STK35 DDX55 ATAD2 FARSA MYH13 ROS1 MSH4 PMS1 ATP6AP1 MSH2 MAP3K14 ME1 ADCY1 SMARCA4 ULK4 STK38 DDX54 ABCF3 RTEL1 CDC42BPA RFC5 CSNK1G2 NME4 PAK4 ICK ABCF2 ACSF3 NUBP2 DNAH1 HK2 BMS1 RAD51 HLCS FARSB STK25 MAP3K9 PFKM MARK4 SNRNP200 NME7 CHD3 CDK5 POMK ERBB2 NUBPL SMC2 PNKP ADCY6 CENPE EIF4G1 GNE SRCAP EARS2 MYO15A DDX52 HSPA7 GLYCTK MTHFD1 TP53 CBWD1 TSSK4 SEPHS1 PAICS TIMM44 EPHB4 UBE2C NPR2 RIPK3 ADCK2 OAS3 PI4KB NAT10 TK2 TTLL5 BRSK2 KIF24 MOK ALPK1 DDX41 MAP3K19 MAP2K2 ACSL5 NLRC5 ERCC3 PRKAG1 ROR2 SLFNL1	up	***
MIR3666	0.0000312	0.0007266	0.5573322	-0.2662071	-1.512270	339	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 CIT TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	***
BIDUS_METASTASIS_UP	0.0026422	0.0263635	0.4317077	0.3307169	1.512160	186	MCM10 FANCI CCNB1 CENPF PAIP1 PBK TTF2 DEPDC1 RACGAP1 CENPA ECT2 CDC6 TPX2 CCNB2 TYMS CAND1 BUB1 AURKA MPHOSPH9 RRM2 PRKDC WDHD1 FNDC5 KIF11 LMNB1 CHEK1 MAD2L1 KNSTRN NUSAP1 PLOD2 ASF1B CDK1 BIRC5 ANKRD54 GMNN FEN1 NF1 SRD5A1 VBP1 CDC23 DLGAP5 ADNP MNS1 SSRP1 P4HA1 CKAP5 KLHL23 EFHC1 GID8 SNRPD1 C5orf22 SRSF1 MARCKS TSR1 CCNA2 VDAC1 RFC5 TUBGCP4	up	*
GSE19401_UNSTIM_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_DN	0.0013088	0.0156640	0.4550599	-0.2873155	-1.511793	168	RBP4 SASH1 IL1B FABP4 MIR22HG DDX6 CDC42EP2 SCARF1 COQ7 ANPEP GLS SERPINB9 SRSF2 BAG1 FABP5 LIMS1 THBS1 CCL3 ERP44 NFKB1 ATF3 SELL CCL4 TP53BP2 MARK3 RABGGTB RSRC2 LIN7A HCK CD80 BCAR3 NECAP1 PSMA1 STAT4 SNX29 MN1 JUNB CD83 GYPC ZNF804A IDS LSM1 AGFG1 EHD1 PIK3C3 GEM SRP72 TRAF1 SRSF10 ULK2 NPAT NFKBIA ADORA2A PDE8B ITCH MT2A DNAJB5	down	*
MIR1468_3P	0.0000015	0.0000532	0.6435518	-0.2492718	-1.511566	541	PRMT8 EREG GCOM1 IL1A SECISBP2L RBMS2 GATA2 CPEB2 RDX LRRFIP1 INSIG1 TMEM170B CD44 PLEKHF2 TMOD3 STXBP6 BMPR2 SRSF7 S1PR1 PRKAR1A MEF2A GALNT18 LAMP1 EOGT PPM1D CCNL1 ZEB2 DNAJB14 EDEM1 TRA2B TACC1 HECW2 PPP1R15B MTF1 PLXNA2 FOXP1 GLS GPBP1L1 PEX5L EIF4E DACH1 FOXJ3 PLXNA4 IL18R1 TRAF6 LAMTOR3 SPRY2 TFRC FBXO8 TIPARP AGO4 PRDM16 MTMR6 SCP2 KCNMA1 SORBS1 BNIP2 DENND6A LIN7C KLF4 RUNX1T1 ID3 TMED5 CEBPA SOCS2 KLF7 ZNF24 CLIC4 SNIP1 RBMS1 GPR85 CCND2 EPS15 CUL5 CLIP4 FAM76B NCKAP5 CNOT6L FOXN3 TMEM9B CREBRF VAMP3 PDIK1L PHTF2 HCFC2 PDCD6IP TMTC1 C20orf194 GLUD1 PDE5A BMP3 UHRF2 VPS26A SKIL SMU1 MBNL2 PCGF5 KBTBD8 FSD2 HOMER1 APH1B CGGBP1 EPC2 ZNF407 GRIK1 AGFG1 CTTNBP2 PPTC7 MAPK8 TSHZ3 XYLT1 NAP1L5 CR1 BTBD7 AKIRIN2 DDHD2 TMX3 TCF4 STRN SMCR8 DCK DPM1 ZBTB11 MCUR1 HBP1 GNA13 ATAD2B ARPP19 HELZ BMP2K GEM RBL2 ARAP2 INTS6 EXOC2 MIER1 ITPRIPL2 MGAT2 LMOD1 POLR2M PSME4 ZDHHC21 TBCEL BCAT1 TIMP3 FOXJ2 B3GNT2 TMCC3 LDLR NRP2 FAM13B GSPT1 WDFY3 PUM1 SPOPL	down	***
GSE30083_SP2_VS_SP4_THYMOCYTE_DN	0.0008295	0.0110013	0.4772708	-0.2842404	-1.511300	175	FAM167A ST8SIA6 HVCN1 HHEX TMEM150B SPN SNX10 LY86 IBA57 CLEC10A S1PR1 CLCF1 ARSB GM2A CYB561A3 LAIR1 IL18R1 GRN CYP4V2 PPP3CC RHOB EVI2B AHNAK MPEG1 CASP1 RRM2B PDE3B HOPX HPSE PLEK N4BP2L1 DSE S1PR4 SGK1 CTSS SOCS3 IL2RB AQP3 STAT4 IFNGR1 IRF8 FAM43A TBX21 RHOQ RIN2 PEA15 KCNN2 ACADL GEM SELPLG IER5 GIMAP5 ZBTB25 ITGAE	down	*
MIR493_5P	0.0000179	0.0004594	0.5756103	-0.2591377	-1.511251	388	MGAT3 IL1A DENND5A TRHDE GATA2 CPEB2 LRRC8C RAPGEF2 TTC7B TMEM170B EGR2 OTUD1 RASAL2 CITED2 CDH13 VAMP2 HMGCR MEF2A DSCAML1 AGTPBP1 GNPTAB SH2B3 NLK FZD4 REV3L PAG1 DACH1 SLAIN2 FOXJ3 TCF7L2 ZMIZ1 HMGN1 FOXO1 KLF4 PRKD3 ZFAND5 FBXL3 NPR3 SEC24B DOCK9 NPAS3 M6PR FRMD4A PTGER3 CAPZA2 WASF3 CUL5 RSL24D1 KIAA0408 USP16 AFF3 NCOA1 PIAS1 BTG1 SERTAD2 FMNL2 KIF13A NDNF SF3B1 JUN JPH1 SHOC2 IFRD1 EEA1 SP3 PIK3R1 MBNL2 PCGF5 CREB1 SLC10A7 DENND4A NDST1 CELF2 TMEM128 SNX9 NECAB1 HIVEP2 USP7 HSF5 TCF4 MCUR1 NAB1 PIK3C3 MAP3K2 ANKRD12 POLK ATAD2B RXRA PRDM8 LDLRAD4 TNFAIP8 ZNF143 ITPRIPL2 SPARCL1 SEC63 ACAP2 LRP12 MFAP5 PTCH1 SSH2 KPNA4 MBD5 LIMCH1 SIN3A NFKBIA LTBP3 LDLR RHOT1 MT2A PUM1 PURB MIER3 PAPSS2 HAT1 REEP1 STARD13 VPS13D KALRN CDC14A CLIP1 GJC1 KCNJ6 ZNF385B HMGCS1 ENDOD1 HIPK1 CLOCK ITGB1 SLC38A2 KIAA2026 HP1BP3 FAR1 CTDSPL2 PPFIA1 WNT5A UNC50 MTSS1 TSC22D2 SERP1 RAD21	down	***
GO_MUSCLE_TISSUE_DEVELOPMENT	0.0001123	0.0021273	0.5384341	-0.2646100	-1.510519	306	RBP4 CCM2L TBX3 BMP2 SIK1 ENG EGR2 CAV1 GPCPD1 S1PR1 HMGCR PRKAR1A MEF2A CDC42 TGFBR3 TGFBR2 HEG1 RHOA KCNAB1 JPH2 TBX2 MYOZ1 LMNA CSRP1 BTG2 CAV2 HLX PPP3CA RB1 WNT3A HNRNPU TCAP FOXC2 TIPARP TNNC1 YBX3 ZFAND5 ARNTL ADAMTS9 NR1D2 ATF3 ID2 MIR24-2 SMAD7 ZMPSTE24 TBX5 VAMP5 CYP26B1 MYH11 MAFF MIR17HG AKIRIN1 TGFB2 LMOD3 MTPN SRF RBPJ SLC8A1 COPS2 NOTCH1 ADRA1A DDX17 FOXN2 IFRD1 DDX5 CREB1 HOMER1 NDUFV2 POGLUT1 FOS CACYBP PKD2 SAV1 TGFB1 MIR23A PIM1 MEIS1 MYOCD GATA6 ACTN2 RGS2 RXRA FGF2 PDLIM5 FKBP1A ARRB2 OSR1 EDN1 PTEN SKI FGFR1 MIR548C NRG1 ZFPM2 SMAD4 EGR1 GREM1 CDON CFL2 SVIL GJC1 MAPK1 MYH10 ITGB1 NOG EFNB2 CCNT2 CALR WNT5A PAX5 PLN	down	**
GSE6875_TCONV_VS_TREG_DN	0.0055666	0.0463248	0.4070179	0.3382992	1.510503	152	PRR15 RUVBL1 POLQ NOVA1 PPP1R14D DGCR8 CDC25A SLC4A4 CCNF DNAI1 TNNT2 AP4M1 CLHC1 CCT5 WDR3 MPO AKAP1 CHAD BRI3BP PLXNA1 HEBP2 TOPBP1 WNT5B PON1 UQCR11 ATIC GOT2 ACSBG2 ACTR3B RNF207 ETFB ATAD3A RNASEH2A IFI27L2 MZT2B SALL4 TUBA8 MRPL4 SYT1 IQCH ZBTB7B NAGS RRP9 TTC34 EXOSC5 POLR2I LSM4	up	*
GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_UP	0.0011809	0.0144779	0.4550599	-0.2838104	-1.510481	177	CXCL3 RAMP3 IL1A RBMS2 ZC3H12C F2RL3 LYVE1 CDH5 SUSD2 IL1RN TRIB1 SBDS ITGA5 LITAF SERPINB9 NFE2L2 AKT3 RHOB SLC7A2 IL10 MOAP1 SOCS2 CDKN1A CXCL2 ATF3 CCL4 KPNA3 MAFF PROCR PDK4 IL6 INPP5B RAB8B ELP5 ATP11A RHOJ CCR7 IFRD1 CD83 EGLN2 SLC3A2 TREX1 ADPRM SAV1 SOD2 PDE4B ICAM1 SESN1 CTTNBP2NL ADAMTS4 NSUN4 SIN3A TIMP3 EDN1 NAA15 MT2A SPHK1 JDP2 SPSB1 CD70 SERPINE1	down	*
GSE12366_GC_VS_NAIVE_BCELL_UP	0.0043215	0.0384212	0.4070179	0.3337667	1.510027	173	HELLS BIK BUB1B MND1 CDCA7 GINS1 BAIAP2L1 PLK1 ESPL1 SOX9 GAPDH CCNB2 UHRF1 MCM4 MCM2 TYMS DTL GFPT1 GPER1 MPHOSPH9 CDCA5 PRKDC RAD54L FHOD3 MCM3 RNFT2 CHEK1 HES6 NCAPG2 TMEM106C ASF1B BCAS4 ENPP3 PEG10 RAPGEF5 CCNE1 KIF22 HMGN3 ANP32E AAMP CKAP5 CENPM RPA1 ROMO1 TDP1 DPY19L2 GINS3 CEP152 MCRS1 SLC2A5 CCDC167 PFKM SRP9 CTTN SMC2 BCL6 CENPE CBWD1 SYNE2 MRPS27 UBE2C NCAPD3 NPR2 SMARCB1	up	*
ZNF436_TARGET_GENES	0.0000982	0.0019041	0.5384341	0.3102796	1.509872	384	ANKRD18A FAM201A KLC3 DDX11 LAD1 DNAH2 EPN3 HBA1 ELOVL6 GALNT6 EYA2 IQCE GCNT3 SLC2A1 PLEKHA6 TTC39A SPDEF STAB2 IGFBP6 ACOT8 ZNF221 SPINT2 PLEKHA7 GRB7 HPS3 ASPHD2 LIPE-AS1 EPS8L1 POLM RFXANK AURKA SSPO GTPBP3 TMEM132A ANKRD19P MDFI KISS1R SLC4A11 ZNF226 SARS2 C2orf72 PIH1D1 AKT2 CNGB1 PKMYT1 EEFSEC FBXL19 LRRC45 CCDC136 UQCR11 BTBD2 CCDC78 PLOD2 SUPT5H CROCC BCAS4 SSUH2 EEPD1 ATIC ZSCAN25 ANKRD54 REEP6 MAP3K10 PACSIN1 TSPAN31 KXD1 PBLD SEMA4F PRR22 KCNH3 CATSPERG ARHGEF16 ATP6V0E2 DVL3 LONP1 DOK4 PCSK4 HDAC1 S100A9 MTND5P11 HID1 SPAG1 ZSWIM3 ETV4 MDGA1 RAI1 RPA1 UBXN6 FIBCD1 TFCP2L1 ABCA7 PRMT1 SRPK2 NOSIP OVOL2 PRKD2 SMARCC2 SF3A2 AP2S1 COG5 TSC2 RBM42 ECH1 HAGHL PAK4 TMEM44 TRAPPC9 TMPRSS9 ATG4D TRAK1 ZNF573 LZTS3 SIRT6 TCF3 TRIM62 CMTM8 ZMAT2 TIMM44 ESPN TRPV3 NELFA SPATA20 CSTF1 BEAN1 UNC119 LASP1 SLC38A10 DEPDC4 C4orf48 PPARGC1B NELFB GCC2 TMEM259 APRT ZNF514 SCAMP4 GGA1 RASAL1 STARD10 ARHGEF19 TEFM ECE1 SAMD11 NDRG1 CACTIN LRP8 SHKBP1 ABTB1 ADAT3 SMAD3 PC KLHL17 CERKL PPP2R2C PFKL RBX1 ECHDC2 SLC23A1 PRR5 GPR137 FBN3 RNASEL COL6A3 MYO7A CIC RAC1 NBEAL2 SH2D3A ZNF746 FAM83G CIZ1 FBXO2 SRC HSD11B1L	up	**
GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_UP	0.0057503	0.0474211	0.4070179	0.3354849	1.509743	162	MCM10 E2F8 TRAIP ILDR1 CEP70 CDC6 NNT UMPS CCT6A CLCN2 KIAA0895 RANBP1 TTLL4 TNNT2 PCCB TMEM177 KIF2C TFR2 WDHD1 MRPL3 WDR66 YEATS2 C7orf50 RAD51AP1 SPC24 PKMYT1 IDH2 CKS1B FAHD2A HARS2 KCTD7 ERC2 PSMG3 GIPC1 GRAMD1A ATP7B NDUFA11 YDJC TSNAXIP1 LONP1 KIF22 ZMAT5 SLC22A23 SGSM3 ACSL6 CENPK TNK1 SASS6 ASB6 PLEK2 LSM7 ENOX1 LPIN1 VPS33B GADD45GIP1 GTF3C5 MAPK8IP3 TRIM67 PIGQ NOS3 SFXN2 SRM MRPL2 RASAL1 COL5A1 STARD10 SCUBE3 MLLT3 MMP14	up	*
ASH1L_TARGET_GENES	0.0000000	0.0000026	0.7195128	0.2948253	1.509658	1134	ONECUT2 FAM227A MDM1 HJURP RUVBL1 CEP89 CDC45 TICRR ZNF273 C1QTNF6 ZMYND8 CHEK2 CCNB1 CENPF DROSHA GBAP1 C21orf58 GGCT KIF18B TTF2 CHCHD6 PIF1 BRCA1 CDCA7 CREB3L4 ZNF138 CDCA2 RACGAP1 ANKZF1 CABIN1 ASPM NABP2 MSTO1 FLAD1 SAP30L-AS1 IFT27 CDCA8 CENPA ECT2 ACOT8 TPX2 E2F3 CCNB2 ZNF714 GOLGB1 ZNF117 ERV3-1 CCNF TDRKH LIPE-AS1 ZWINT SMUG1 ZNF107 ZNF726 GOLPH3L WDR62 HMMR CLSTN3 RAB11B-AS1 CHAF1A BOD1 HLTF STAP2 EMC9 TP53BP1 CLHC1 BUB1 CCDC77 EEF1E1 TOP2A EXOC4 RPL32P3 AURKA EME1 CBX3 GTPBP3 KLHL25 CACNA1G COASY TMEM45A RAD54L MRPL27 PASK MCM3 ZNF226 CDC25C TRIM11 ZNF785 PYCR2 TARS2 RNFT2 CHD6 SARS2 CCDC148 C7orf50 ACTL6A CKAP2L NFYA PSMD4 CBY1 DNAAF3 ANKRD16 SPC24 BRIP1 EEFSEC FBXL19 MRPS30 PHB LRRC45 FADS2 CNOT3 ARL16 ERCC2 C4orf47 TULP3 INCENP CKS1B EFCAB11 ISOC2 CBX5 MRPL37 ANAPC5 ING4 CDK1 PABPN1 CDK12 EFCAB6 CCDC61 LMCD1-AS1 KCTD7 RFWD3 CCT3 NUDT2 PHF12 ANKRD54 AAGAB SUN1 GTF2E1 POLR3K UNG REEP6 DGAT2 PMEL RNF181 BPGM PSAT1 NARF KLHDC9 PAXIP1-AS1 FEN1 TSPAN31 EZH2 ZNF775 TNPO2 MRPS12 THAP8 RALGPS1 SAPCD2 OARD1 LCA5 TTC16 SNRPE RTP4 ZKSCAN5 STK11 IFT52 KPNB1 ANKRD39 TPD52L2 CHCHD2 SNRNP25 GIPC1 VBP1 GOLGA3 ZNF687 ILF2 EDEM3 CEP192 CDC23 AKR1E2 CCZ1B VIPAS39 DLGAP5 NEK10 SPG7 SLC26A2 PSMA5 MTOR ZNF133 FHIT UROS HIRA HMGN3 CCDC130 COX7C ACBD4 ROGDI COPS7B UBE2Q1 DPH2 ZNF417 TK1 PLEKHA8 PCSK4 CENPQ RHBDD3 AKAP8L ESCO2 MLEC ANP32E PKP4 NUDT16 ZNF300 AGPAT5 LAMTOR2 DAP3 LIN37 ZSWIM3 ZSWIM1 DNAJC11 TM9SF4 IQCH FKBP14 PRRG2 CCZ1 CCDC159 AAMP NAIF1 ELAC2 CCT7 NR6A1 CCDC137 CENPK TADA3 UBQLN4 CKAP5 PWWP2A PSMB3 ORMDL2 CENPM ZCCHC17 CA11 GBF1 RRP9 AP3M2 FAHD1 BCL2L1 NOL6 CDR2 ABCA7 MRPL24 ARVCF KDM4B WDR83 MED24 PRMT1 CKAP2 XRCC4 NOSIP MCM5 TDP1 ZRANB3 UIMC1 DDX23 C5orf22 LANCL2 SCYL3 RAB3D C1orf109 LRCH4 SNX11 ZBTB9 KATNB1 DOLPP1 POLR2I PDIA4 LSM4 RAP2B SUGP1 TMEM45B STK35 TCERG1 COPZ1 SPSB3 ZNF837 AP2S1 ZNF622 ZNF519 SH3D21 GLO1 ATP6AP1 FCF1P8 CYTH2 RPS26 APC2 MSH2 NCDN RBM42 ZNF195 PRR11 ZNF93 ZNF169 BBX DDX54 ZNF257 DENR ZNF66 RNF121 TXNL4B DOHH ZNF436 CEP164 PRPF31 NUBP2 ZNF384 NBR1 ZNF292 TOMM40L FBXW11 NLGN2 SRP9 LLPH PAXIP1 NME7 LINC00240 NDUFS8 AGBL5 TBCB ALKBH6 GNA12 BCAS3 BCL6 TMEM260 MAU2 CENPE POLR1A PFDN4 RHPN1 HGS TMEM256 ZNF526 PPIA PNN TTC9C RHPN1-AS1 SFXN5 DCAF11 ZSCAN20 TMEM38A TPRN SLC39A1 ZNF253 COX6B1 STK11IP TTLL5 FAM222B FTSJ3 TMEM161A MSANTD4 TRAPPC6A SETD5 ANKRD11 CYB5B PHRF1 CSTF1 CYHR1 COPE RTN4IP1 RCN2 MORN4 PDXP MBTD1 ZDHHC13 NSUN5 ZNF678 PPP1R13L PDK2 WDR63 UTP18 HRAS TRAFD1 PCNT CDK11B SRI TBC1D10B PPP2R5E PNPO FBXO5 LCMT1 ZNF688 CYB5RL ABHD2 TNPO3 FASTKD3 TMPO TOMM40 SLC2A8 ZNF774 SMYD3 GLRX5 ZNF77 TYK2 PMVK MPZL1 MTMR4 ZNF43 MTR HOMEZ TMEM167A MTRR TRIM59 HINT2 SHKBP1 MBD6 AP2A1 GDF11 WDR89 RMI1 HNRNPAB PARP16 PC LRPPRC FMN1 AFMID LYPLA2 MTHFD2 STRIP1 DHX38 CALM3 PAN2 METTL17 EVI5L ELMO2 ZNF675 SAP30L KLF5 WDR25 BBS12 DDX49 MAEA TUBGCP5 RAB4B STAG3L1 PDXDC1 ZNF691 CTPS1	up	***
GSE27786_BCELL_VS_NKCELL_DN	0.0008744	0.0114657	0.4772708	-0.2838994	-1.509637	176	GATA2 CYP27A1 MIR22HG CD44 RTN3 BMPR2 CTDSP1 SLC15A3 SLCO2A1 PDE2A NCEH1 DNAJC3 MCTP1 ADIPOR1 SPRY2 RAB14 ZMIZ1 ARRB1 PTGIR SGTB KLF9 MAP1LC3B ITPK1 RIT1 RECK FRMD4A TM6SF1 DSE NCOA1 EMP3 TMEM9B VAMP3 PRKRA NSMAF KIF13A INPP5B PDCD6IP CYB5R1 OSTM1 ATXN1L MBNL2 HSD17B12 RALB	down	*
GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_WITH_EGR2_DELETED_DN	0.0017804	0.0195704	0.4550599	-0.2881439	-1.509518	157	STAC GLIPR2 TRPV2 EGR2 PCOLCE2 ANAPC15 GGA2 ABCG2 ANXA5 FOXP1 PTX3 C1orf162 ADRB2 TIPARP KLF11 STK17B GNAQ IL7R HGSNAT PRCP S1PR4 SCEL AQP3 SLC35E4 DNAJA1 PODXL KLHL18 SNX1 CAP1 PREX2 EGLN2 WDFY4 CTTNBP2 UBB HNRNPA2B1 DYNC1LI1 DOK2 ANKRD13A ADAMTS15 OPN3 CALHM2 RTN4 PIP4K2A CALCOCO2 EXD3 MEGF9 GPD1L	down	*
GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP	0.0013866	0.0163078	0.4550599	-0.2867697	-1.508921	168	SIDT2 SPN LRRC8C RAPGEF2 SAMHD1 USP47 ABCB1 NUMB UBR3 PPP1R15B CYB5A PAG1 TOR1AIP1 EPM2AIP1 RAB14 PTPN21 UHRF1BP1L GAA ZADH2 SCAF4 WDR48 EXOSC8 PEAK1 TM9SF2 PAFAH1B1 NRBF2 STK24 HGSNAT NCKAP1L DCP1A APPL1 NECAP1 CELF1 OSTM1 EPC1 CREB1 MORC3 CGGBP1 TRAPPC10 FAM204A PHF3 TEX14 VAMP4 POLK PLA2G15 SLC43A2 FKBP1A CYB5R4 BRWD1 CEPT1 DOCK10 RORA NABP1 GIMAP4 FEZ2 CBX7 ATP11B ITGAL FAM8A1 ZFYVE1 HP1BP3 CCNT2 MICAL1	down	*
GSE17721_PAM3CSK4_VS_CPG_2H_BMDC_UP	0.0051129	0.0435822	0.4070179	0.3371467	1.508824	156	SAA2 BHMT DOC2A CLGN NIPSNAP1 EFNA4 LAMP5 EBF3 ACAD9 RGS6 ZFP64 SMARCC1 FOXA1 TPBG NUP155 MPHOSPH9 TPCN1 SMYD2 LPIN3 TMEM45A FAM162A ARMC12 TOPBP1 PTGDR2 LINGO1 SRCIN1 DNAH5 TCTE1 SMG5 PUS1 LMNB2 HDHD3 KY ZNF239 METTL22 NUDT16 GRIN3B IFNAR2 NIF3L1 NOL6 CAPRIN2 HMCES LRRK1 POLR3E WDR45B PSMB4 PRMT5 LRRC14 PRSS22 MRPL9 IKZF4 GNE SRCAP TRIB2 GOLGA2 SLC38A4 MRPL20 CEP290 APRT RALGPS2 CHD8 PARP4 CRYZ DCLRE1A ZAP70 UBE3C CRCP SLC44A1 SLC25A35 ZBTB48 C1orf43 RPS10 OPN1SW GLB1L ASPRV1	up	*
GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP	0.0040871	0.0367711	0.4070179	0.3370890	1.508584	155	PCSK6 FAM83F GRIA4 KCNK5 EPN3 CP ANLN DGCR8 LMLN FAM169A CUL9 EEF1E1 NUP155 WIPI2 ASPHD1 CCL28 RPAP2 C2CD3 CBX5 CDK1 C1orf112 VANGL2 POLR1C LRRC56 GAL3ST4 UNC45A SNRNP25 TRIO OSBPL3 ACBD4 DNM1 TSSK3 SGSM3 C15orf41 TNK1 SASS6 TUBG2 KRT8 ARVCF GAD1 TCHP STRBP APOBEC2 CCNA2 PRR11 MSS51 RNF123 NME7 CENPE SMPD4 ZMAT2	up	*
GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_UP	0.0056504	0.0468397	0.4070179	0.3406349	1.508407	144	TF HKDC1 FUT6 BDH1 JPH3 DGCR9 PBK LCN2 LHB IFT122 EIF2B5 HOXB7 FERMT1 PAH PLS1 ACY1 HNF4G TSGA10 MCM7 ZNF443 KHK C7orf26 PTPN3 ZNF512B ZNF45 EPHA1 PLA2G2A NAV2 IGSF3 SNCAIP GIPC1 LGR5 NFATC4 METTL22 ECEL1 EPB41L4B CCZ1 ZNF76 TFCP2L1 ZNF223 DHX8 TBC1D30 ZSCAN32 SUGP1 ZKSCAN7 TXNL4B YBX2 PRSS22 MAP3K9	up	*
GO_REGULATION_OF_LEUKOCYTE_MIGRATION	0.0013660	0.0161591	0.4550599	-0.2878099	-1.507766	163	HMOX1 SWAP70 GCSAML ADTRP SPN C5AR1 CD9 GAS6 IL23A RHOA APOD ANXA1 PLA2G7 ADA ADAM17 JAM3 CRK BST1 PTAFR THBS1 CCL3 SELP CCL4 JAM2 MIR24-2 XCL2 DUSP1 OXSR1 AKIRIN1 NCKAP1L IL6 LRCH1 RAC2 RHOG PTGER4 CCR7 DAPK2 DOCK8 CD74 FPR2 MIA3 CD81 LGALS3 KLRC4-KLRK1 CCR1 GPR18 ADAM10 CCL20 CCR6 ICAM1 EDN1 KLRK1 MTUS1 ANO6 GREM1 SERPINE1 C5AR2 CX3CR1 C5 TREM2	down	*
GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR	0.0031005	0.0298873	0.4317077	0.3215054	1.507577	237	TP63 FOXM1 CHEK2 CCNB1 DDIT4 BRCA1 E2F8 GTSE1 L3MBTL1 AURKB TPX2 TFDP2 RBBP8 ACER2 CDK5RAP3 CASP2 EXO1 RHNO1 EEF1E1 AURKA ATR E2F2 MSX1 SMYD2 CDC25C SOX4 TOPBP1 CHEK1 MDM2 PRMT6 PERP BRIP1 BLM PML CNOT3 PLA2R1 DYRK2 ING4 CDK1 E2F1 DNA2 CNOT11 TAF6 PRKAA2 NOP2 STK11 TRIM24 CNOT2 FHIT RAD9A SSRP1 MYBBP1A HDAC1 NOC2L BCL2L12 CHD5 ATAD5 RAD50 SUPT16H TWIST1 RPA1 PRMT1 ANKRD1 TFAP4 PRMT5 MSH2 RFC5 TNKS1BP1 PAXIP1 CHD3 CDK5 TP53 TAF4 RAD1 E2F7 RRS1 MUC1 IFI16 PRKAG1 TTC5 RFFL PPP1R13L TOP3A PDK2 SPRED3 HINT1 ATRIP NPM1 BATF NDRG1 PCBP4 EHMT1 RMI1 ELL3 E2F4 TP53RK	up	*
GSE45365_NK_CELL_VS_CD11B_DC_UP	0.0059681	0.0487219	0.4070179	0.3437577	1.507248	129	PDE11A MUC16 SRGAP3 PTPRR B3GAT1 TRAIP SP5 ASPHD2 CUL9 MSX2 IDO1 ABCC5 KIF11 SOX11 CYP2W1 BTBD2 C2orf50 SPACA4 CCNJL KCNK12 STEAP3 GDAP1L1 ZNF606 MBD4 ASGR2 PCSK4 GINS2 VIL1 NUDT16 MMP7 CCDC51 PROX1 L3MBTL2 COL26A1 RPUSD1 KRT8 MAB21L3 CHRNA3 VWA3A ZNF212 DTNB ZFP14 SIRT6 TRIM62 PIGL SLC35G1 ASCL2 ZNF619 TMEM63C WDR63 HDAC10 PRR12 ROPN1L ZNF414 DRD4 LZTS2	up	*
SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_UP	0.0045849	0.0400811	0.4070179	-0.2976590	-1.506952	130	SEMA3G TMEM126A FABP4 PTPRB MMRN1 CAV1 CASP12 SBDS CLEC14A HDC LHX6 HNRNPDL SLC25A37 SDCBP AOC3 PRKD3 KLF9 LY96 CD300C MPC1 SPRYD7 USP16 MYO1C EBAG9 TYROBP CSTA RHOJ IFRD1 FAM177A1 CPA3 TEX30 NAB1 ACYP2 SERINC3 SESN1 SPARCL1 ARRB2 B3GALNT1 GIMAP5 DIXDC1 PLGRKT PTEN SPOPL ACAT1 SPPL2A TREM2 SLC26A11 PTGS1 PIAS2	down	*
MIR300	0.0000159	0.0004142	0.5756103	-0.2606635	-1.506888	382	USP12 EMP2 GPR65 PTPRE RAB3C BDNF FYN SEC22C CORO1C HEATR5B QKI BMPR2 GTF2I P2RY13 NR3C1 VAPA PPM1D IER2 SEMA6D CLCF1 UBL3 PPP1R15B CAMTA1 PEX5L ZNF697 SLAIN2 FOXJ3 PPP3CA ATP6V1H KDSR CWC22 EFCAB14 MAP2K3 FOXO1 SGTB SORBS1 MPEG1 ACSL3 KLF4 ITM2B CADM1 AXL PNRC1 ACTR3 MATN2 GNAQ KIAA0408 PAFAH1B1 KPNA3 HES1 RABGGTB CNOT6L USP25 RBPJ CREBRF RYBP PHACTR2 PPP6C PDE5A JPH1 EPC1 ELOVL7 IPO7 FYTTD1 SKIL MBNL2 MALT1 RC3H1 REL CGGBP1 TMEM128 AGFG1 SLC25A24 PTP4A1 HIVEP2 SLC4A5 BTBD7 ZNF521 ATG2B CHRAC1 ZBTB1 PDS5B CEP76 KHDRBS1 CNOT7 HBP1 ORC2 GNB4 CRY1 GNA13 RIMKLB PHF2 ARAP2 PDLIM5 SCN7A RTN1 ARIH1 PTCH1 ULK2 MBD5 LYSMD3 NFKBIA CEPT1 SCAI B3GNT2 KIF1B RORA ITCH RHOT1 ZFPM2 EIF4A2 NUP160 RAB2A YTHDC1 ABI1 PSIP1 KALRN ZNF800 LIN52 CLOCK FUS MYH10 XPO7 TRPM7 UBE2W WNT5A WAC MTSS1 AKAP12 TES PAXBP1 ARHGAP44 ZFYVE21 NR5A2 ITGA6 ORC4 NKTR RAB11FIP2 PLCB4 EDIL3 FNIP1	down	***
GO_RESPONSE_TO_GROWTH_FACTOR	0.0000026	0.0000866	0.6272567	-0.2480106	-1.506588	578	SMAD6 TRIM71 SEMA6A TMEM100 ACVRL1 SOSTDC1 HHEX SFRP4 IL1B CLEC3B CAT WNT4 P2RY1 GREM2 RDX RAPGEF2 BMPER RAMP2 BMP2 CDH5 ENG KL BDNF FOLR1 FYN CD44 INPP5K BAG4 CAV1 BAIAP2 CITED2 TBC1D7 BMPR2 FGF10 MIR27B NR3C1 TGFBR3 GAS6 CBL TGFBR2 IER2 RHOA PDE2A TMPRSS6 ANXA1 MIR146A MMRN2 LTBP4 ADAM17 RAP1A TMEM204 ITGA5 HSPB1 NLK FZD4 CAV2 GATA3 NR4A1 CRK SFRP1 SPRY2 ZFYVE16 ZEB1 UBE2D3 RAB14 NODAL PTPN12 IL10 MAP2K3 ROCK2 PRDM16 DUSP3 SDCBP NPNT LIMS1 KLF4 ZNF423 ROCK1 DAB2 THBS1 CLDN5 PDE8A CEP57 SMAD7 VEPH1 NUS1 HES1 HTRA4 MIR17HG ANXA3 TGFB2 NRROS RBPJ MYO1C FLT1 ADAMTSL2 APPL1 MAGI2 JUN NOTCH1 LTBP2 BMP3 SHOC2 RAPGEF1 FERMT2 SKIL DDX5 GRB2 CREB1 FSTL3 NDST1 FGFR4 FOS SPRY4 UBB KLB RUNX3 SORT1 TGFB1 EHD1 PARD6A TGIF1 ZFYVE9 MIR23A TGFB1I1 LRRC32 MYOCD TOB1 NPTN GATA6 LTBP1 SMAD2 LDLRAD4 FGF2 EPB41L5 EPN2 ARRB2 ACAP2 CDKN1C UBE2D1 EPHA2 CREBBP ING2 GTF2F2 EDN1 ETV2 PTEN SKI LTBP3 KIF1B FGFR1 NRP2 GRB10 IQGAP1 EHD4 SMAD4 FEZ1 FLT4 SPHK1 SKOR1 HNRNPH1 ADAMTS7 ARHGEF18 SETX HTRA2 ACVR1C EGR1 GREM1 DUSP6 DKK3 CX3CR1 MAPK1 ZYX HAS2 ZFP36 CD109 NOG	down	***
GO_NEGATIVE_REGULATION_OF_NERVOUS_SYSTEM_DEVELOPMENT	0.0002787	0.0045897	0.4984931	-0.2743943	-1.506457	241	SLC6A4 TNR DAB1 SEMA6B SEMA3G SEMA6A EDNRB DENND5A IL1B RAPGEF2 FIG4 ARHGEF15 DDX6 CTDSP1 RHOA SEMA6D MIR146A ASAP1 SEMA3B PAQR3 EIF4E PPP3CA WNT3A ARHGEF2 ZNF365 LRP4 PTPRO TRIM46 DAAM2 REST ID3 VIM ID2 PAFAH1B1 RUFY3 HES1 KREMEN1 GNRH1 SRGAP2C KANK1 MYLIP ID4 CNTF IL6 PSEN1 NOTCH1 CTSZ CNTN4 BAG5 IFRD1 LSM1 RTN4R PRKACA TRAK2	down	**
GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP	0.0009412	0.0121248	0.4772708	-0.2832821	-1.506355	176	KLF13 HVCN1 SPN SLC6A12 LPL LMO2 RASAL2 BMPR2 FXYD2 ALAS1 NFATC3 C11orf94 STARD9 TACC1 RAP1A AHRR IFI30 HLX LCP1 UBE2D3 PTPN12 EFCAB14 CSRNP1 MED11 ST3GAL2 RRM2B PLEKHM3 UHRF1BP1L CTSD LAPTM5 PTPRC SMAD7 PPP2R5C TBC1D4 NCOA1 NRROS HRH1 RHOG RAPGEF1 IDS NOL7 OGFRL1 AGPS AZI2 RUNX3 ATPAF1 ZNF175 AZIN1	down	*
GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP	0.0028885	0.0282764	0.4317077	0.3337272	1.506311	167	HELLS DEPDC1 PIF1 BRCA1 RACGAP1 E2F8 ANLN DGCR8 PLK1 ESPL1 UHRF1 MCM4 NCAPD2 IKBKE WDR62 KIF15 CENPL EME1 POLA2 TPR MPHOSPH9 RRM2 WDHD1 GPSM2 CKAP2L PIH1D1 MDM2 ANKRD16 ZCRB1 CDKN2C PLOD2 CENPH TRAP1 DNA2 DYNLL2 TNPO2 GBP5 TEP1 GRAMD1A MAN1B1 PPOX CHTF18 ESCO2 MLEC SLC4A2 ATAD5 GALNT7 CKAP5 DYNC1LI2 UTP20 IL12RB2 ATAD2 RTEL1 TUBGCP4 RAD51 SNRNP70 MAPK8IP3 PRPF3 NCAPD3 RASGRP1 DNM1L THAP3 NCAPH ACIN1 PCGF6	up	*
GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_UP	0.0013424	0.0159908	0.4550599	-0.2842784	-1.506099	173	FFAR4 SIRPB1 GCOM1 GPR15 GATA2 SPN SAMHD1 FCER1A SUSD2 CLEC10A STX11 MARCO IL1RL1 APOD PPP1R15B NAAA HDC SERPINB9 RGCC IL18R1 AKT3 MTHFR ATP10A STAT5A CCL22 SELL KLRD1 EMP3 DDHD1 OASL RGS18 OSBPL9 PCGF5 GYPC PRKCE PXK TMEM192 AGFG1 ICAM2 CPA3 SPOP SMCR8 FPR2 GNB4 LGALS3 TSPO IER5 SETDB2 SEMA4A TIAM1 ESYT1 ACTB KATNA1 CD3G KLRK1 B3GNT2 NRP2	down	*
GO_REGULATION_OF_CELL_SUBSTRATE_ADHESION	0.0022807	0.0236693	0.4317077	-0.2837160	-1.506056	178	LIMS2 AJAP1 ACVRL1 FOXF1 TEK DLC1 ATXN3 WNT4 EMP2 CORO1C MYADM CDH13 CDC42 NEDD9 RHOA APOD CD36 ITGA5 FZD4 CRK SFRP1 ROCK2 DUSP3 NPNT PTPRO LIMS1 BST1 ROCK1 THBS1 PEAK1 NINJ1 KANK1 FAM107A UTRN NDNF NOTCH1 RAC2 MAP4K4 CCR7 PIK3R1 PRKCE HSD17B12 PPM1F EPHA3 CLASP2 MACF1 SPOCK2 ABI3BP UNC13D ARPC2 EPB41L5	down	*
GSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_DN	0.0015811	0.0179422	0.4550599	-0.2840189	-1.505454	181	ADCY9 PTP4A2 FYN PPP4R1 GFOD1 CTDSP1 TGFBR3 AGPAT4 ZEB2 MAP3K8 TTYH2 STOM ADRB2 SRGN CD58 AGO4 AHNAK TNFSF12 DENND3 HOPX CCL4 PRF1 SMAD7 KLRD1 MATK PIK3R5 IL2RB SH3BP5 BTD TBX21 CST7 TIGIT MBP NKG7 PIK3AP1 ATXN1 DOK2 STK40 PLEKHO2 KAT2B CLEC2B SYT11 PITPNA TMEM184B S100A4 CTSC PDE4A MCOLN2 PIEZO1 SLFN11 MAP4 ITGAL ITGB1 TOR2A MAN1A1 ATP2B4 KATNAL1 CD226 SRXN1 GZMB TNFRSF1B SLAMF7 KLRG1 IL10RA PIK3R3 JAZF1 RALGDS GZMA	down	*
GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN	0.0021062	0.0223096	0.4317077	-0.2924453	-1.505191	151	RAB11FIP1 IL1A ZC3H12C HCAR2 CCRL2 CDC42EP2 PRPF38A STX11 IGSF6 BTG2 MAP3K8 FOXP1 HIPK3 PLXNA4 BIRC2 ZFAND5 FBXL3 NFKB1 GPR85 ATF3 C9orf72 CCL4 PLEK N4BP1 SPRYD7 RASGEF1B DDHD1 SOCS3 MTMR14 NXPE3 CD83 MALT1 REL ACSL1 PELI1 HIVEP2 NAB1 CNOT7 PIM1 SOD2 TAGAP BRI3 GPR18 RNF2 ICAM1	down	*
GO_NEGATIVE_REGULATION_OF_GROWTH	0.0007084	0.0097271	0.4772708	-0.2783068	-1.505072	202	SLC6A4 TNR RBP4 SEMA6B SEMA3G SEMA6A ACVRL1 PPARG WFDC1 FBP1 DCSTAMP SOX17 BMPR2 TGFBR2 SEMA6D WWC2 MYOZ1 SEMA3B ADIPOR1 ADRB1 ADRB2 SFRP1 WNT3A PPT1 TRIM46 SOCS2 CDKN1A ST7L INHBA ADIPOR2 TBX5 MIR17HG CDKN2AIP TGFB2 BTG1 SERTAD2 PPP2CA PRDM11 NOTCH1 HSPA1B APBB2 IFRD1 NPR1 RTN4R WNT11 SAV1 TGFB1 OSGIN1 APBB1 MEIS1 RGS2 SEMA4A RTN4 PTCH1 MT1M ULK2 STK4 PTEN MT2A SMAD4 GREM1 CDKN1B ING1 DCUN1D3 OSGIN2 NOG MT1E MUL1 WNT5A	down	**
MCBRYAN_PUBERTAL_BREAST_6_7WK_UP	0.0010153	0.0128472	0.4550599	-0.2830676	-1.505065	175	GPD1 EPAS1 SECISBP2L CLEC3B LIPA HSD17B11 DDX6 QKI EIF3CL NFATC3 ZEB2 SH2B3 NFIX MALAT1 KCNK3 GM2A PRELP FZD4 MS4A1 STOM SIRPA TNS1 ARHGEF2 ITSN2 MAPK8IP1 EPB41L2 KIF1C SORBS1 PPP6R3 CCND2 SFTPD CRIM1 MYO1C PDCD6IP ZFP91 ETS1 PIK3R1 NDST1 IP6K1 EHD2 MAPK8 TIMP2 EHD1 CYGB APLP2 SOD2	down	*
TGTGTGA_MIR377	0.0014644	0.0168938	0.4550599	-0.2859927	-1.504833	168	PRX HMOX1 EDNRB EGR2 QKI S1PR1 ARL8B AGPAT4 ZEB2 ZBTB4 CACNA2D2 FZD4 RNF182 CAMTA1 EIF4E NDEL1 CD93 ADARB1 TAPT1 KCNMA1 MVB12B GPR85 NCOA1 FOXN3 SRF HMBOX1 CPEB4 CUL4A ETS1 RABGAP1 PPM1F CELF2 GRSF1 FLNC BTBD7 AZIN1 NUP153 PHF3 BAZ2B C16orf72 CNOT7 ATXN1 MACF1 MIER1 LRP12 FBXO30 IPO5 PSME4 RET RNF38 GTPBP8 C21orf91 NRG1 NAA15 PUM1 REEP1 EGR1 CDON CDKN1B	down	*
MIR194_5P	0.0011737	0.0144097	0.4550599	-0.2866879	-1.504621	167	CXCL3 SLC12A6 OSBPL11 C18orf32 LPXN LRRFIP1 TTC7B EMCN QKI DYRK1A ERG HBEGF RNF125 REV3L DACH1 PPP3CA ATP6V1H FLI1 CPED1 PTPN12 MTMR6 BNIP2 LIN7C ZFAND5 TMED5 SEC24B MGAT4A CADM1 USP44 ELMSAN1 PRICKLE2 OSTM1 SLC10A7 NIPSNAP3B EPC2 CDK14 PPTC7 BTBD7 CHORDC1 RSBN1L TBRG1 NRN1 RXRA CEP170 SSH2 PARVA PAIP2 C21orf91	down	*
MIR130A_3P	0.0000407	0.0009123	0.5573322	-0.2640984	-1.504617	342	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 PHF3 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	***
GO_TRNA_METABOLIC_PROCESS	0.0049594	0.0425136	0.4070179	0.3379331	1.504184	148	SLFN13 METTL1 AARS2 QTRT1 EEF1E1 PUS7 GTPBP3 LARS2 NSUN2 TRPT1 AIMP2 TARS2 SARS2 TRMT61B ANKRD16 TRIT1 HARS2 EXOSC2 DTD1 TYW1 POLR3K RTCB PARS2 TRMU PUS1 ADAT1 AARSD1 TSEN54 ELAC2 YARS2 CPSF4 IARS2 DUS1L POP7 METTL2B NSUN6 DUS4L RPP38 DUS2 FARSA CTU1 CDK5RAP1 WDR4 FARSB TARBP1 OSGEP EARS2 POP4 TRUB1 SEPHS1 CDKAL1 DTD2 NAT10 RPP25 EXOSC10 CTU2 DUS3L MARS2 PPA1 ADAT3 ELP6 TP53RK PUSL1 EXOSC7 TSEN15 DARS2 RPP40 TRMT12 NARS2 URM1 THADA CPSF1 TRMT1 TRMT10B DDX1	up	*
GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_UP	0.0021519	0.0227091	0.4317077	-0.2841914	-1.504090	169	SWAP70 DENND5A SH2D3C CTSW SAMHD1 AQP9 ZEB2 ANXA1 ENTPD1 BTG2 LAIR1 PPP3CA ARHGEF2 PTGIR YBX3 MVB12B SOCS2 TMBIM1 CDKN1A ITGAX VIM AQP4 ID2 TM6SF1 PLEK KLRD1 PDHX SGK1 IL2RB TYROBP IFNGR1 RHOJ ELOVL7 CD7 NKG7 PIK3AP1 DUSP5 CLDND2 LGALS3 NQO2 ACTN2 RGS2 RXRA RBL2 SELPLG ARHGAP18 CTSC KLRK1 LYST SAMSN1 USP48 SMPD1 CSF2 ZYX SSC5D S1PR5 RCBTB2 NFIL3 RPA2 DOCK5 METRNL GZMB MYO1F KLRC1 C15orf48 APOBR EIF4E3 F2RL2 SLAMF7 ANXA6 KLRG1 CAPG CD47 SNAI3 GZMA IQGAP2	down	*
MODULE_197	0.0037861	0.0347837	0.4317077	0.3376788	1.503970	149	DDX11 FOXM1 TFAP2A CCNB1 NPAS1 NDC80 TBRG4 CDK4 PLK1 PTTG1 SOX9 E2F3 CCNB2 RBBP8 CDC25A MYBL2 NCAPD2 KIF23 KNTC1 BUB1 KIF2C WDHD1 HOXC6 MCM3 SOX4 ACTL6A MAD2L1 PPP5C TULP3 CDK1 BIRC5 E2F1 EZH2 CBFA2T2 DNMT1 CCNE1 CDK3 KIF22 SSRP1 NFATC4 CDC7 CXCL1 MCM6 NEK4 RCC1 TXNL4A PMS1 CCNA2 ZNF195	up	*
GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_UP	0.0010123	0.0128402	0.4550599	-0.2841361	-1.503739	172	RAB11FIP1 DENND5A SNX10 MYD88 INPP5A ELMO1 FRAT1 CD22 TGFBR2 TMX4 ZEB2 PBX3 ASH2L SLC25A37 C14orf132 KLF4 PXDC1 SCAF4 ITPK1 HOPX LBH ALOX5AP HLA-DQA1 IL24 TDRD7 HCK ARHGAP17 WASF2 PIKFYVE RABGAP1 TNFRSF10B RASSF2 PPM1F TNFSF13 RUNX3 CD74 ZNF136 ATAD2B TIMM22 IQSEC1 TPT1 SIK3 VSIG10 CD19 CCDC92 TNFSF9 DLST AIM2 IL16 ZFYVE26 PLAG1	down	*
GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP	0.0051692	0.0439306	0.4070179	0.3325788	1.503648	174	EGLN3 FANCI PBK KIF18B GINS1 RACGAP1 TRAIP POLE SPP1 STIL NUF2 ALDH18A1 CDC6 TFDP2 CCNB2 UMPS TMCC1 TDRKH MAP7 MKI67 TOP2A CPD DPCD RRM2 CDCA5 PASK SPRY1 KNSTRN CKS1B NUSAP1 ASF1B CDK1 DNA2 RNF181 PSAT1 ABHD4 FGFR1OP HSPA4L DGCR6 AKR1E2 KIF22 KY ASNS LCLAT1 CENPK SLFN12 MCM5 CREB3L2 ATAD2 ZNF580 TMEM17 CCNA2 TIGD2 STAB1 LPGAT1 FBXW11 IKZF4 GMPR2 SEPHS1 CISH PPP1R16A NCAPH CD38 METTL4 DSN1 SMYD3 MPZL1 COG6 GCSH MRPS6 TMEM214 ALPK2 TXN2	up	*
GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_DN	0.0044344	0.0391363	0.4070179	0.3317533	1.503367	175	GRIK2 BDH1 NUP107 NEK2 CCDC34 CENPF PAIP1 BRCA1 MRPL46 METTL1 TRAIP ECT2 TPX2 PRC1 AACS TMCC1 ZFP64 TMEM81 COX11 WDR62 BUB1 TMEM177 POC1A WDHD1 AKAP1 KIF11 FANCD2 GPSM2 ANG ABCB6 MTG1 C2CD3 CENPH POLR3K USP42 NLN CBX1 LGR5 ILF2 GBP6 GEMIN5 FZR1 GK5 ATAD5 CENPK PPHLN1 CHCHD1 ZNF428 SLFN12 TDP1 PYGO2 DNAJC21 ADM FAM3C WDR4 RAD51 ARHGAP11A	up	*
MIR19B_3P	0.0000020	0.0000703	0.6272567	-0.2495481	-1.503213	553	SLC31A2 EREG ABHD5 DLC1 OSBPL11 USP12 KLF13 SECISBP2L ADCY9 NUP54 RAPGEF2 ARRDC4 RCOR1 OTUD1 CCDC88A DDX6 LONRF1 QKI GPCPD1 BMPR2 S1PR1 MEF2A WBP4 EOGT MOB1B CCNL1 ZBTB4 UBL3 HECW2 RAPGEF4 RAP1A NLK KLF10 FOXP1 HIPK3 ADRB1 PLXNA4 MED26 ANKRD29 UBE2D3 RAB14 ATP6V1B2 FBXO8 ATP10A RHOB MTMR6 BNIP2 DENND6A REST SOCS5 KLF7 RBMS1 PDE3B HNRNPUL2 ID2 ARC PNRC1 CCND2 FRMD4A EPS15 CCSER2 ADIPOR2 MBD2 CLIP4 SLC6A6 PRICKLE2 FKBP15 KPNA3 AFF1 FAM76B NCKAP5 CNOT6L SRGAP2C BTG1 CREBRF VAMP3 PDIK1L VPS37A PKNOX1 PHTF2 LRRTM2 SGK1 KIF13A EBF2 SOCS3 APPL1 MAGI2 RAB8B HCFC2 C20orf194 ZFP91 DESI2 HIC1 PDE5A BMP3 ATP11A RABGAP1 BAG5 ATXN1L SKIL MBNL2 FAM43A KBTBD8 ATL2 GTDC1 HOMER1 ZNRF3 RASSF2 GRSF1 CD164 MSMO1 SRSF6 PPTC7 SLC35F1 MAPK8 TSHZ3 RIN2 FLNC BTBD7 EMC7 ZNF521 SMCR8 TGIF1 ZFYVE9 SBF2 YTHDF2 SKIDA1 ZBTB11 CNOT7 MAP3K2 ATXN1 HBP1 GABARAPL1 NPTN MACF1 PLAA SERINC3 ARPP19 INO80D SYT11 ARAP2 MIER1 WDR1 RTN1 EPN2 VPS4B CYP2U1 SP100 MEX3C BRWD1 G3BP2 RBMS3 LIMCH1 DOCK10 PTEN DUSP7 CAMSAP2 RORA ITCH LDLR C2orf42 DOCK4 NR3C2 WDFY3 DNAJA2 EIF4G2 DMXL2 AFTPH ZFYVE26 MB21D2 SERPINE1 AQP5 CFL2 CLIP1 ZNF385B HIPK1 ATF2 MAPK1 CLOCK CNGA3 DCUN1D3	down	***
GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_DN	0.0023463	0.0241926	0.4317077	-0.2831201	-1.503042	174	SEMA6A ACVRL1 OLR1 RAPGEF2 CYP4B1 STX11 CDC42 IL1RN FAM49A ADA MTF1 PRELP ZNF410 LCP1 TXN MAP2K3 KCNMA1 SLC12A4 DENND3 VRK2 GMPR NFKB1 CCL4 DUSP1 ARL4A VAMP5 TP53BP2 SRSF3 CD48 DNAJA1 RCAN1 PPP1R15A WTAP PTGER4 CCR7 CD83 CXCL5 CST7 MSMO1 DUSP5 ANKRD12 KAT2B SOD3 ICAM1 CGRRF1 RTN1 TRAF1 GLUL STK4 BCAT1 NFKBIA LDLR MT2A ABI1 CSF2RB DUSP6 ENDOD1 S100A8 MT1E SLC9A3R2 LAMTOR5 FCGR3A PDPN NR4A3 MSC RNF19B CYP1B1 ADAM19 PLXNC1 CRLF3 SERPING1 IL10RA SQLE MT1G CRYBA1	down	*
GO_ACTOMYOSIN_STRUCTURE_ORGANIZATION	0.0015504	0.0176837	0.4550599	-0.2893420	-1.502918	160	PHACTR1 DLC1 WNT4 GPR65 ARHGEF15 TMOD3 INPP5K BAG4 S1PR1 PRKAR1A MEF2A CDC42 EPB41L3 CIT RHOA MYOZ1 CSRP1 RGCC SFRP1 TCAP CNN1 SORBS3 EPB41L2 ROCK2 ARRB1 SORBS1 ROCK1 MYH11 LMOD3 SRF TMOD1 WASF2 PDCD6IP ARHGEF10 PTGER4 PIK3R1 PPM1F WNT11 CLASP2 ACTN2 WDR1 EPB41L5 LMOD1 TMOD2 LIMCH1 CUL3 RAPGEF3 EDN1 EPB41L4A SYNPO2L CNN2 SMAD4 CFL2 MYH10 FHOD1 ITGB1 ZYX CDC42BPB PPFIA1 TRPM7 LDB3	down	*
GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP	0.0054012	0.0452714	0.4070179	0.3339223	1.502714	163	LEMD1 CEP89 PARPBP PRIM2 BET1 TTK CDK4 ANLN PLK1 AURKB TPX2 FIGNL1 PRC1 MCM8 CAND1 NCAPD2 MAGEF1 RUVBL2 TOP2A YKT6 KIF2C E2F2 C14orf93 ERAL1 GPSM2 TARS2 ASS1 DNAJC9 ORC6 TIMM50 ZMIZ2 EFCAB1 VPS72 EFTUD2 ACBD6 ILF2 C19orf47 NMRAL1 TK1 MGMT MAGOHB TDP1 HAUS6 STK35 INTS8 CCNA2 DENR MRPL55 PDAP1 ABHD10 CLUAP1 ZWILCH PPFIA3 MXD3 VDAC3 SMC2 GLYCTK CDC25B FBXO45 E2F7 C4orf46 SCAF1 SPIDR METTL4 PLK4 RBL1 ZNF771	up	*
E2F_Q4_01	0.0041615	0.0372589	0.4070179	0.3258401	1.502022	197	CDC45 GPAT2 UCHL1 CDCA7 AGFG2 E2F8 CDC6 E2F3 GAPDH MCM4 MCM2 CDC25A ORC1 EPHB1 RANBP1 WDR62 CASP2 MELK PAQR4 AP4M1 KNTC1 MAP3K13 POLA2 MCM7 PRKDC MCM3 TOPBP1 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 POLE2 GMNN E2F1 UNG EZH2 TNPO2 THAP8 ZNF827 KPNB1 DNMT1 ZNF687 ACBD6 FANCG INTS7 NDUFA11 EPHB2 PCSK4 ANP32E DNAJC11 ETV4 KDM3A SASS6 PPP1R8 HMGA1 MCM6 SRSF1 GINS3 OVOL2 ATAD2 EIF3K PATZ1 PRIM1 RNF121 YBX2 ABCF2 RAD51 ARHGAP11A MXD3 SMC2	up	*
GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_DN	0.0011407	0.0140834	0.4550599	-0.2886625	-1.502003	154	WEE1 TMEM52B GPR65 CCRL2 PLEKHA1 KCNN3 ACER3 PDCL SPCS3 TRA2B C10orf25 RANBP9 SLAIN2 BNIP2 DENND6A MVB12B ACTR3 ELK3 FAM76B CMTM6 TYROBP FOXN2 RC3H1 MORC3 GFPT2 BLOC1S6 AGFG1 YTHDF3 PSMD12 ZFAND6 PDS5B PDE12 TMEM230 ATXN1 CLASP2 DCTN4 VPS4B FBXO30 RBM18 G3BP2 CREBBP COPS8 ACADM SCAI FAM13B EIF4A2 ANO6 BMI1 EXPH5 HIPK1 ATF2 DYNC1I2 CSNK1G3	down	*
GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN	0.0018730	0.0203206	0.4550599	-0.2885991	-1.501773	159	ARRDC4 PDE1B AKAP7 EML1 PAFAH1B2 AGPAT4 MOB1B STARD4 LMNA CAV2 GATA3 TFRC TUBB6 FBXL5 KDSR DUSP3 LRRC57 PXDC1 ITIH5 ATF3 IRAK2 MIR24-2 SHE GNAQ UBASH3B STK24 SPIN1 C2CD2 GLUD1 RPS6KA1 TNFRSF9 YWHAZ APH1B GFPT2 YPEL2 CRYZL1 TEC TSC22D1 LGALS3 SETDB2 RTN4 RAB5A ARL14EP CCR9 KIT PSMD6 ATP6V0A1 TMEM30A TMEM43 HMGCS1 ZFP36 FAR1 PTGS1 CD69 SLC25A19 ARHGEF12 ATP8A1 KATNAL1 PLCB4 SRXN1 ZFP1 EIF4E3 PNP PLCL1 MTDH SCAMP1 DCTD TMEM64 STK10 STX2 PADI2 SLC37A2	down	*
GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN	0.0052591	0.0443562	0.4070179	0.3321566	1.501739	174	DDX11 HJURP ZMYND8 TTK NIPSNAP1 EIF2B5 UMPS CAND1 VILL COQ3 CETP NUDT1 DPY19L2P2 TOP2A PUS7 MRPL3 PASK MCM3 SIDT1 TMEM63A PERP PHB ZNF32 CBX5 URI1 PKD1P1 CMTR1 STEAP1 SYN3 ITPR3 PELP1 LRRC8D COPS7B ZNF544 AGPAT5 DAP3 COPS6 SULT1B1 PFAS TSTA3 LIMA1 KLHL23 IARS2 MRPL24 MRPS33 NOSIP USP21 ADD3 ABCD4 COPZ1 INTS8 DZIP3 CLUAP1 ERBB2 TRIB2 DHRS3 NELFA PWP1 CORO1B CD38 TMEM62 EIF2D NSUN5 TFG RPL36	up	*
ZHOU_INFLAMMATORY_RESPONSE_LPS_UP	0.0001735	0.0030484	0.5188481	-0.2680351	-1.501549	294	CXCL3 SEMA6A EREG HSPB7 ARHGAP31 DENND5A USP12 CD55 ZC3H12C IL1B RDX RAPGEF2 CD44 CCRL2 CLEC12B DDX6 NEDD4L FOSL1 UBE2FP1 IL23A DNASE1L3 TMPRSS6 ATP2B1 ADAM17 BTG2 RNF144B FZD4 LITAF PTX3 EIF4E LDHAL6A AGBL1 MAP2K3 CSRNP1 STAT5A SNAI1 PTPN21 LIMS1 KLF4 PLAUR DRAM1 NFKB1 C4orf33 NPAS3 CXCL2 IRAK2 AQP4 CCL4 HTT MAFF PRICKLE2-AS3 MOB3A KREMEN1 VWF SNN NINJ1 AXDND1 CD80 IL6 RBM34 OASL PNMA2 PPP1R15A WTAP ELOVL7 IRF8 OSM MAPK4 GRIA1 REL ACSL1 NIPAL4 ITGA9 TEC DUSP5 SLC24A1 GPR84 ADORA2A-AS1 N4BP2L2 CCL20 ICAM1 IL18 PDLIM5 ABL2 EPB41L5 NBN	down	**
GSE7460_TCONV_VS_TREG_LN_DN	0.0005579	0.0080404	0.4772708	-0.2812242	-1.501386	185	CXCL3 GPR15 DENND5A ZC3H12C LPXN CCRL2 C3orf70 ABCB1 ENTPD1 MAP3K8 KLF6 CYP4V2 AHNAK AGR3 ST3GAL2 SOCS2 SOCS5 HOPX AXL SHE UBE2B ELK3 MATN2 PEAK1 UBASH3B TBC1D4 CNRIP1 TDRD7 PRKRA PHTF2 KIF13A IL2RB RAB8B ST6GALNAC4 PTGER4 CD83 IRF8 TNFRSF9 DENND4A ZBED5 CD86 ZC3H12D CD81 GABARAPL1 STON1 SERINC3 RXRA BMP2K CCR6 GEM SESN1	down	**
GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN	0.0045894	0.0401074	0.4070179	0.3354705	1.501340	155	BBOX1 SLCO5A1 SPICE1 KIF20A DGCR5 UCHL1 CIB2 KIF18B TTC39A METTL1 AURKB TPX2 CCNB2 CCNF SPINK1 LIME1 CDT1 EXO1 KCNMB3 TMEM177 POLA2 RAD54L SARS2 IGKV1-5 ZKSCAN1 PKMYT1 WNT5B ASF1B CDK1 GJB3 ANKRD26 PDK1 FER1L4 G6PC3 FAH SLC37A4 TK1 IL15RA IGHM DHRS1 CLINT1 DYNC1LI2 XRCC4 RABEPK LANCL2 GADD45G PYCR1 APOBEC2 ARSA GTF3C5 WDR76 CHPF2 ZNF91 TIMM44 UBE2C COPZ2 DHRS9 ANKRD11 DNAAF1 DHDDS GSTP1 CNKSR1 BAK1 CDC34	up	*
GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN	0.0054128	0.0453090	0.4070179	0.3308470	1.501244	176	TRIP13 TBRG4 CDK4 EIF2B5 ALDH18A1 CDC6 PMS2 RUVBL2 NDUFB8 DNPH1 EXO1 CISD1 BUB1 AURKA MCM7 RRM2 ZNHIT1 CHEK1 ORC6 MRPS11 MRPL36 CCT3 POLR3K MRPS2 MRPL17 LARP1 TSPAN31 EZH2 MRPS12 UQCC2 EIF6 EFTUD2 EDEM3 DPP3 SNRPA KIF22 MRPL11 ZSWIM1 MARCKSL1 TIMM13 CPSF4 RPRD1B STOML2 DUS1L MRPS33 CKAP2 HAX1 UNC119B FARSA RER1 USP39 PRPF31 NDUFA8 ACP1 SMC2 RPN1 SNRPC DTD2 MRPL20 NDUFB7 NUP93 COX17 NCAPH LUC7L3 DRG1 MRPL12 CLPP EXOSC10 TOMM40 CDC34 GCSH TIPIN MTHFD2 PFKL ITPA PTCD2 EXOSC7 MRPS7 MRPL35 MRPL13 UGDH RRP1B PRDX2 TARDBP DPY30 PMPCB PLSCR1 GART SSNA1 DDX1 UBE2M	up	*
GSE20727_CTRL_VS_H2O2_TREATED_DC_UP	0.0016030	0.0181077	0.4550599	-0.2831532	-1.500137	173	RAB11FIP1 SIDT2 PDLIM2 MNDA PTP4A2 PLEKHF2 HEATR5B MEF2A MANBA CD1C ZDHHC2 RNF144B PARVG ABCG1 PTPN12 STAT5A SDCBP KLF4 SLC38A11 ID3 RBMS1 ELMSAN1 SLC6A6 MAPRE2 PI4K2A HCK BTG1 TBC1D5 SERTAD2 CCNY RAB8B CELF1 IFNGR1 GRB2 GTDC1 HOMER1 UVRAG EGLN2 TFEB GSAP CD1D IRS2 CD81 GNA13 CCR6 MOB3B SF1 BLOC1S2 SIK3 ACTB	down	*
GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP	0.0020103	0.0215257	0.4317077	-0.2877060	-1.499893	156	KMO SLC12A6 SOX18 PECAM1 FCER1A AQP9 PLEKHA1 WBP4 CD22 DNASE1L3 OLFML2A PBX3 SERPINB9 LAIR1 ADARB1 AGO4 FOXO1 BST1 YBX3 KLF9 MYO15B KCTD20 UXS1 PER1 BTG1 PRCP MITF LRCH1 IFNGR1 MTMR9 OSM ZNF350 SPRY4 XYLT1 EPHA3 VAV3 CCP110 IRS2 AOX1 TPMT ZNF136 APLP2 GRK4 SESN1 INTS6 CXCR4 MFAP5 TTC28 LYST P2RX1 NR3C2 HEBP1 EHD4 ATP6V0A1 EXOG ZBTB16 CHML	down	*
WANG_LMO4_TARGETS_DN	0.0000920	0.0018016	0.5384341	-0.2628348	-1.499858	318	RAB11FIP1 TUBD1 GATA2 CPEB2 U2AF1 RDX TMOD3 SAMHD1 LONRF1 TBC1D7 PLEKHA1 S1PR1 CDC42 FBXO3 PSMD5 USP47 PPM1D CLCF1 PTS CHMP1B BZW1 AHRR CSGALNACT2 SPTBN1 ATP6V1H RAB14 DIABLO SLC7A2 TBC1D9 DUSP3 SAP30BP ACSL3 RNFT1 MED6 ZNF24 UBQLN1 PLEKHB2 CAPZA2 RPF1 KBTBD4 SPRYD7 BACE1 LIN7A ACTR2 TOPORS MYLIP SYNPO2 SAR1A DDX20 JUN VAT1 OSTM1 EPC1 MPZL3 COBLL1 RBM22 AP3B1 SNX22 NOL7 GPRC5A ZNF407 MEAF6 OCIAD1 TMEM192 SLC3A2 RRN3 KRTCAP2 NECAB1 BCAS2 BAZ2B MTMR2 CDC37L1 C16orf72 EXOC1 PHF11 STX12 ATAD2B CHURC1 ELP2 SRP72 CYP2U1 NSUN4 FDX1 C17orf49 RASSF8 ZDHHC5 PAK2 FAM126B DLST ITCH IQGAP1 ZFAND2A PURB FEZ2 PAPSS2 RABGEF1 SUGT1 KAT5 MRPS28 KALRN HMGCS1 UBA6 SH3GLB1 RB1CC1 NUP88 SLC26A11 PPFIA1 WDR41 CHMP4A DAPP1 EXOC6	down	**
MODULE_26	0.0055827	0.0463834	0.4070179	0.3332779	1.499814	163	CPNE4 CDHR2 BBOX1 MDM1 ZDHHC4 PRTFDC1 UBE2T FA2H MSTO1 CYP46A1 SLC7A9 DYNC1I1 KHDC1 STRA6 RPAP1 EMC9 MAP3K13 TFR2 B3GNT3 TRIT1 MYOT MRPL36 APLP1 FAHD2A LINGO1 SERTAD4 CENPJ TYW1 RBCK1 TRIM2 ACTR3B SMO NLN GDAP1L1 ZKSCAN5 IFT52 HSPA4L	up	*
GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN	0.0013923	0.0163574	0.4550599	-0.2817843	-1.499698	177	DAB1 LPIN2 HSD17B11 GPCPD1 BCL2A1 IL1RN HSPE1 UBL3 ADAM17 LMNA LATS2 LITAF SLC7A11 SERPINB9 PPP2R2A RGCC TRAF6 SRGN UBE2D3 TUBB6 CWC22 FABP5 AHNAK HNRNPA3 YBX3 CDIP1 STX3 CDKN1A M6PR KPNA3 ANXA3 MARK3 PDK4 PPP6C STAT4 MAP4K4 EEA1 PIK3R1 CD83 AGFG1 SNX9 HIVEP2 STXBP3 HNRNPA2B1 TGIF1 SLIRP RNF2 RPP30 IL18RAP SERTAD1 RAB5A VPS4B TRAF1 B3GNT2 ANXA11 LDLR GSPT1 DNAJA2 SUGT1 CENPC FTL C6orf62 WAC KCMF1 SMARCA5 WDR26 PDPN GJB2 CFLAR CCNC IRF4 SRXN1 TPST2	down	*
GSE27786_LSK_VS_NEUTROPHIL_UP	0.0033811	0.0320746	0.4317077	0.3322393	1.499595	167	PLEKHA6 BRCA1 GINS1 DGCR8 IFT27 CCT6A TRIM45 EXO1 TMEM177 SAE1 TTLL12 HOOK1 FAM162A THYN1 RAD51AP1 FLNB MRPL36 C12orf75 CENPH ZNF260 ZMIZ2 SLC25A13 MECR METTL3 TRAPPC12 RNF150 ZNF623 MZT2B ST14 LONP1 SLC37A4 LMF1 SLC22A5 GSTK1 TSEN54 ESR1 RAI1 NPRL3 RRP9 C16orf58 MRPL28 MYEF2 LSM4 HAGHL MRPS25 INO80E ZSCAN22 DTNBP1 TRUB1 SHISA2 RAD1 IMMP2L CYB5B ISLR PAQR8 AKAP9 PSMB10 MRPL2 DUS3L GLRX5 POT1 TXN2 NUP214 TUBGCP5 KIF3A PPM1G NDUFA9 TUFT1	up	*
MIR4275	0.0048468	0.0417447	0.4070179	-0.2961954	-1.499542	130	LYVE1 LRRFIP1 PTPRB QKI UBR3 STARD4 SH2B3 COQ7 MASP1 TMEM41B UBE2D3 ZNF423 UBQLN1 LRRC40 NR1D2 USP44 CCND2 SLC6A6 KPNA3 FAM76B USP25 ARHGAP17 ELF1 NEK7 SF3B1 DNAJA1 DHX15 AP3B1 RNF24 PTP4A1 YTHDF3 CHORDC1 EPHA3 TMX3 FEM1B KHDRBS1 MAP3K2 MICU3 EPB41L5 SRSF10 TBCEL FAM126B GSPT1 RAB2A PMAIP1 EIF4G2 HNRNPH1 ZNF326 PSIP1 MB21D2	down	*
GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN	0.0015421	0.0176171	0.4550599	-0.2849794	-1.499501	168	EPAS1 IL1A DENND5A PECAM1 GPR65 MIR22HG AKAP7 MYD88 BCL2A1 TMX4 CD36 EIF4A1 SH2B3 CD5 PICALM RGCC IL18R1 SPTBN1 KLF4 SCAF4 SLC25A32 MPC1 C4BPB MAPRE2 HCAR3 KLRB1 TULP2 STAT4 CYCS DNAJA1 MALT1 SNRK KLF2 PSMD12 ZBTB1 TGIF1 MIA3 MAP3K2 NFYC PIM1 CLASP2 GPR18 ICAM1 RLF SP100 SCPEP1 GSPT1 PMAIP1 PPP1CB AFTPH CHP1 NR4A2 ENDOD1 FUS ECD	down	*
GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP	0.0016931	0.0188204	0.4550599	-0.2828237	-1.499119	181	HMOX1 TSPAN4 PPARG MIR22HG LY86 FOSL1 TRIB1 GGA2 LMNA NDEL1 TMEM41B SETD3 RHOB MOAP1 AHNAK ACSL3 ZFAND5 SPAG9 RIT1 CDS2 CD302 DUSP1 SLC6A6 DEGS1 PRCP SERTAD2 VAMP3 RYBP BCAR3 PGD SRSF3 JUN IDS STX5 YWHAZ IP6K1 SLC3A2 FOS ATP6V0D1 STRN KIAA0232 JMJD6 MEIS3P1 ATP6V0C PLEKHO2 TSPO ME2 PITPNA CDKN1C ARIH1 JMJD1C DNAJB9 NRG1 GRB10 CREG1 TLK1 RNH1	down	*
GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN	0.0011348	0.0140193	0.4550599	-0.2907753	-1.499012	149	EPAS1 CXCL3 IL17RB TIE1 SIK1 CCRL2 MYADM CALCRL NR3C1 SEMA6D LMNA KLF6 GATA3 NR4A1 RB1 RGCC CSRNP1 SORBS1 AFAP1L1 ZFAND5 SLC7A8 STK17B MYO1B CDKN1A DUSP1 PLCD1 PLAC9 RBPJ SLC25A3 AREG CREM KCTD12 GLUD1 JUNB PPP1R15A SKIL LPCAT2 ATP13A3 PTP4A1 CPA3 ISM1 ZCCHC10 IRS2 MYOCD ETS2	down	*
COREBINDINGFACTOR_Q6	0.0003084	0.0050054	0.4984931	-0.2744482	-1.498764	219	GPD1 SLC12A6 CD101 PPARG MIR22HG RAMP2 LMO2 BMPR2 CBL EPB41L3 IL23A ERG NFIX CYP17A1 B3GNT5 UBL3 PICALM CNTD1 LUZP1 HLX ZBTB8A NR4A1 ARHGEF2 DIABLO FLI1 MAFG MPL CCL3 CADM1 PDE3B VIM CCL4 XCL2 FCER1G EVI2A TBX5 IL7R PAFAH1B1 CRTAC1 ADD1 FOXN3 ETF1 RYBP BCAR3 RGS18 PSMA1 RHOG PDZD2 RASSF2 EPC2 TIGIT AZIN1 SRSF4 CD6 CYGB TAGAP CCR1 STON1 LTBP1	down	**
GO_POSITIVE_REGULATION_OF_PROTEIN_KINASE_B_SIGNALING	0.0026951	0.0267814	0.4317077	-0.2941842	-1.498639	140	EREG RAMP3 TEK ENG KL FYN BAG4 FGF10 GAS6 HBEGF GATA3 SPRY2 TCF7L2 TXN PDGFA THBS1 CCL3 EPGN AXL HPSE PINK1 PIK3R5 CD80 AREG RAC2 RHOG CCR7 PIK3R1 GRB2 OSM FGFR4 KLB PIK3AP1 TGFB1 CD86 IRS2 FGF2 IL18 ARRB2 RTN4 HSP90AA1 CD19 RET KIT FGFR1 NRG1	down	*
GREB1_TARGET_GENES	0.0000110	0.0003012	0.5933255	0.2965366	1.498614	695	MUC5B ATP6V0A4 ALDH3B2 PPM1H SYT8 SCIN IGSF9 LAD1 CEP89 C1QTNF6 EPN3 RBBP8NL LRIG3 ZMYND8 S100A2 ANKFN1 RGMB-AS1 SDK2 PTPRH TMC1 PRR15L SLC27A2 SPAG17 NIPSNAP1 NAALADL2 CNTD2 SEC14L5 IFT27 NNT ANKRD22 STC2 RBBP8 DNAH3 CA12 GALNT10 C19orf57 TDRKH KIAA0895 SRPK1 VILL WDR90 SPPL2B DNAI1 GOLPH3L KCNH2 OSBPL2 STAP2 SMAGP TRIM29 TOP2A IQCD CARD10 GTPBP3 IFT43 KLHL25 ASCC2 ZNF860 RHOBTB3 TMEM45A AKAP1 C7orf57 LINC00511 XXYLT1 CCDC58 MCCC2 TGM1 CHD6 HEBP2 PROM2 ACTL6A ZKSCAN1 TBC1D8 CNGB1 EHF DNAH11 INPP4B GRHL2 CNOT3 WWC1 PARD3 DLG5 CCDC40 RECQL5 TMED3 ISOC2 CDKN2C CAPN8 PABPN1 EPHA1 SRRM2-AS1 RFWD3 ABHD17C RAPGEFL1 TNK2 ADAP1 POLR3K ABCC11 DGAT2 PMEL ENPP3 CCDC88C TMEM79 PSMG3 RNF207 FER1L4 IGSF3 VPS72 RECQL4 TSPAN1 KPNB1 ANKRD39 TPD52L2 PYROXD2 SNRNP25 DNMT1 VBP1 ZNF687 GRAMD1A RHOC AKR1E2 SPG7 NINL LLGL2 S100A16 PKP3 SALL4 C9orf152 CHTF18 TMTC2 CASP7 AKAP8L KIF21A ATG9B ANP32E RNF224 NUDT16 MAPK10 ZSWIM1 DNMBP ZNF282 CCDC159 ENC1 NAIF1 CCT7 DNASE1 SEC14L2 SLC26A1 LIMA1 PWWP2A DGKA KIAA0100 FAF1 AP3M2 KRT8 KDM4B EML6 MED24 VWA3B ANXA9 UIMC1 MAB21L3 SMIM6 IFITM10 TBC1D16 LRCH4 URB1 KATNB1 DOLPP1 RTKN OVOL2 RGMB SLC1A5 CORO2A CDH11 COPZ1 DOK7 CYTH2 PRR11 GRHL1 ECH1 CANT1 ANAPC2 CSNK1G2 BLVRB PAK4 SYBU OSBPL10 PRSS22 ARRDC1 TNKS1BP1 TRAPPC9 PPFIA3 ERGIC1 TCF25 ABCC5-AS1 CHD3 LRG1 DNPEP ERBB2 UNKL ALKBH6 BCAS3 CLNK RHPN1 FRMD6 NMT1 MCF2L2 EPHB4 UBE2C RHPN1-AS1 KRT80 TUBA1C TPRN SLC39A1 WIPI1 TTLL5 PLXNB1 UMODL1 ASCL2 PPP1R16A ANKRD11 PCTP FAM47E DAZAP1 LASP1 DNAAF1 ZDHHC1 MIOS RFFL PDK2 AKAP9 RBM20 COMTD1 GSTP1 SRI TMEM229B TBC1D10B SCAMP4 ABHD2 TMPRSS4 FAM111B EXOSC10 SLC2A8 RASAL1 NAV2-AS3 TRAF7 CDC34 STARD10 GLRX5 ZNF77 CHD8 BATF PIWIL4 MTMR4 KCNK1 MLLT3 SLC20A2 HOMEZ C1orf194 NDRG1 RAB26 EHMT1 NADK CYB561 AP2A1 ADAT3 SMAD3 RGS3 INHA FMN1 DENND2D	up	***
GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP	0.0051922	0.0440090	0.4070179	0.3353623	1.498573	154	TRIP13 BUB1B IGF2BP3 CDCA2 E2F8 GTSE1 SLC27A2 ANLN STIL NUF2 ECT2 TPX2 PRC1 CCNF DTL NCAPD2 HMMR KIF23 MKI67 KIF15 KNTC1 CLSPN CPD MMS22L KIF11 CDC25C LIG1 CD24 TXNDC5 CKAP2L DET1 INCENP CKS1B ASF1B POLE2 CENPH NUP205 ETFB	up	*
NABA_ECM_AFFILIATED	0.0043429	0.0385266	0.4070179	-0.2984478	-1.498165	119	SEMA6B SEMA3G CLEC1B SEMA6A FCN1 FCN3 CLEC3B CLEC12A GPC5 EMCN CLEC12B CLEC10A SEMA6D ANXA1 SEMA3B PLXNA2 CLEC7A CLEC14A ANXA5 PLXNA4 CLEC1A C1QTNF7 SFTPD CLEC9A C1QTNF2 ANXA3 MUC3A C1QA SFTPB	down	*
GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_UP	0.0053301	0.0448708	0.4070179	0.3365078	1.497839	148	HABP2 ACY3 TSHZ2 CREB3L4 BCL2L15 STC2 SPATS2 PRKCA TAMM41 CBLC ZNF112 THBS4 RRM2 KISS1R HEBP2 ZKSCAN1 DDR1 CKLF GABRB2 CD300A CCM2 PACSIN1 NARF PLVAP MYO19 KCNH3 INTS7 POFUT1 DLGAP5 S100A16 TUBA8 CHTF18 S100A9 CGREF1 POLD1 TYRO3 PARP9 MARCKSL1 CENPK KLHDC3 NAGS CENPV	up	*
GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS	0.0035890	0.0335381	0.4317077	0.3231222	1.497480	206	AK4 ELOVL6 GPAT2 ACMSD GUCY2C NMNAT3 GMPS FLAD1 TYMS UMPS GUCA1B AK8 TAMM41 NME1 IDO1 COASY RRM2 NME9 PKM NME5 CAD IDH2 ALDOA PARP1 UCK2 ATIC SLC25A13 ACSBG2 PDK1 AK7 UCKL1 QPRT NMNAT2 UPP2 DCAKD NADK2 SLC26A2 DHODH TK1 DTYMK AGPAT5 LCLAT1 ACSL6 PARP9 NADSYN1 RAD50 SLC26A1 PFAS ENTPD8 STOML2 ACLY PPCDC NMNAT1 LHPP ME1 ADCY1 NME4 ACSF3 ELOVL4 COX5B NOS1 NME7 VPS9D1 SLC35B3 PNKP ADCY6 MTHFD1 PAICS NNMT PDP1 RNLS NPR2 ENO1 TK2 ACSL5 ACSBG1 NOS3 DGUOK SPHK2 PDK2 ADSL APRT PANK4 PRPSAP2 AK9 SHMT1 NADK PARP16 CMPK2 AFMID HAAO	up	*
GO_SKIN_DEVELOPMENT	0.0026017	0.0261464	0.4317077	0.3221904	1.497009	208	DKK1 PCSK6 TP63 LIPM KRT5 PKP2 PKP1 FOXE1 FA2H ABCA12 KRT16 SOX9 SLITRK5 CYP27B1 LSR GRHL3 FERMT1 KRT15 ITGA2 CLDN1 HRNR MSX2 ITGB4 FLG NSUN2 TGM1 EGFR ABCB6 PERP GRHL2 FLNB ERCC2 IGFBP5 KRT18 VANGL2 GJB3 COL3A1 CDH3 TMEM79 NF1 SMO ACVR1B IRF6 LGR5 ST14 COL1A1 COL1A2 ALX4 TRIM16 CTSV TRADD PKP3 COL5A2 HDAC1 PKP4 KRT19 PPHLN1 WNT10B KRT8 COMP COL5A3 SPINK5 EDAR PIP5K1A OVOL2 KRTAP5-9 PRSS8	up	*
GO_REGULATION_OF_CHROMOSOME_ORGANIZATION	0.0011052	0.0137401	0.4550599	0.3149434	1.496868	286	TRIP13 DDX11 CDC45 BUB1B NEK2 CCNB1 CENPF NDC80 PIF1 BRCA1 TTK DNMT3B NABP2 PLK1 AURKB PTTG1 WDR70 ESPL1 CDC6 MCM2 CCT6A CDT1 CCT2 SPDL1 RUVBL2 SDR16C5 MKI67 BUB1 TOP2A CCT5 ATR TPR MAD1L1 CDCA5 SETDB1 MORC2 ZNHIT1 CHEK1 MAD2L1 XRCC1 PIH1D1 PRMT6 PML NAA40 TADA2A MNAT1 PARP1 ANAPC5 CCT3 FEN1 TRAPPC12 MAD2L2 KLHL22 DNMT1 CDC23 DLGAP5 SMG5 TACC3 HIRA FBXO4 AKAP8L NOC2L ANAPC1 SLX4 ZBTB7B CCT7 RAD50 KDM3A TADA3 CENPV PPHLN1 CDC20 YLPM1 TWIST1 HMGA1 ALKBH4 CDK5RAP2 PYGO2 NSD1 PRKD2 ZNF274 ATAD2 RTEL1 MLLT6 NOS1 PAXIP1 SIRT6 PNKP LIF BCL6 CENPE TP53 SMARCB1 ATF7IP NAT10 MUC1 SART3 SETD5	up	*
GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP	0.0026346	0.0263085	0.4317077	-0.2818655	-1.496381	174	MCOLN1 TSPAN4 LTA4H LPXN SEC22C GTF2I S1PR1 FRAT1 PCYOX1 C1orf21 ACOT2 TTYH2 KANK2 ARL11 FLI1 PER3 DUSP3 MPEG1 KIAA0513 STX3 TLR4 LBH ALOX5AP CD300C MFSD11 PINK1 PEAK1 IL7R MMP19 CREBRF FRY CYB5R1 SNX29 RHOJ IRF8 TPRA1 CELF2 MBP TEC CD81 NQO2 RGS2 MFSD12 SESN1 TIAM1 PIP4K2A GLUL FNIP2 SKI DUSP7 MAN1C1 ZFYVE26 ATP6V0A1 PLAG1 CNR2 BHLHE41 PXMP4 HIPK1 HP1BP3 PTGS1 EXOC6 SGPP1 MAP3K1 ITGA6 CCPG1 DUSP22	down	*
HALLMARK_MITOTIC_SPINDLE	0.0035705	0.0334256	0.4317077	0.3268023	1.496173	187	CEP72 NEK2 CENPF NDC80 PIF1 TTK RACGAP1 ANLN PLK1 ECT2 ESPL1 TPX2 CCNB2 PRC1 CEP250 DLG1 KIF23 KIF15 KNTC1 WASF1 KIF3B BUB1 TOP2A AURKA KIF2C CD2AP KIF11 LMNB1 CDC42EP1 KIF3C FLNB GEMIN4 INCENP NUSAP1 CDK1 CENPJ BIRC5 DYNLL2 NF1 RAPGEF5 NET1 CEP192 DLGAP5 TRIO KIF22 KIF20B SASS6 CKAP5 CDK5RAP2 KPTN KATNB1 MARCKS ALMS1 CYTH2 CDC42BPA ARHGAP5 MARK4 LLGL1 RHOT2 CTTN CENPE	up	*
GSE30083_SP1_VS_SP4_THYMOCYTE_UP	0.0029368	0.0286667	0.4317077	0.3310509	1.495836	172	MUC5B KCNMB2 MEX3A GABRB3 UCHL1 SORD TUBB2B WDR70 CDC25A TDRKH VILL AARS2 SMARCC1 SYTL2 BBS1 CBLC HHAT TMEM132A ABCC5 AKAP1 KLHDC4 REPIN1 SLC45A3 PLOD2 PAK1 PLA2G2A CCT3 ABHD17C TNK2 CTXN1 REEP6 CNOT11 LRRC42 SMO TMEM120B CBX1 LAPTM4B ANKRD45 ALDH7A1 L1TD1 EDARADD MARCKSL1 RPL7L1 CCSER1 WDR35 MARCKS STRBP SERPINI2 ICK WDR4 CAPN10 GTF3C5 TCTEX1D1 F13A1 RBM19 CHL1	up	*
GO_CYTOPLASMIC_SIDE_OF_MEMBRANE	0.0021862	0.0229955	0.4317077	-0.2895772	-1.495357	152	PRMT8 AJAP1 AKAP5 STAC FYN SHANK3 FGR RHOA KCNAB1 ATP2B1 GM2A GNGT2 LITAF CAV2 PPP3CA GNG7 TRAF6 EPM2AIP1 DIABLO BIRC2 CDIP1 PTPRC GNAQ GNAI2 GNRH1 HCK DNAJA1 PALM FERMT2 SNX9 PTP4A1 PKD2 GNAI1 GNG5 EXOC1 GNA13 RGS2 GEM FKBP1A RAB5A TIAM1 ESYT1 TRAF1 SRMS KIT PTEN CYTH1 IQGAP1 HTRA2 CNR2 SPPL2A	down	*
GO_DRUG_BINDING	0.0000000	0.0000002	0.7749390	0.2902840	1.495184	1416	KIF1A ATP10B CPS1 KIF12 STYK1 TRIP13 HKDC1 ABCA13 DDX11 NPC1L1 ENTPD2 ABCC2 HELLS EPHB3 KIF20A DDX12P CYP19A1 GPT RUVBL1 AK4 DNAH2 GPT2 HBA1 CHEK2 BUB1B SLFN13 MYO3B HBA2 PPIP5K1 NEK2 XYLB FRK POLQ UBE2T PBK KIF18B TTF2 GUCY2C PIF1 CHRNG NMNAT3 IP6K3 STK36 TTK CDK4 BRSK1 SLC27A2 KIF14 UBE2Z ABCA12 GMPS STK31 FLAD1 CHRNA7 PLK1 AURKB ALDH18A1 PAK6 SLC6A3 CDC6 WNK2 TRIB3 FIGNL1 MCM4 PRKCA MCM2 RAD54B TYMS DNAH3 PMS2 NWD1 GLDC XRCC2 ORC1 AACS HBB CCT6A MCM8 PIP4K2C LIG3 MAP2K6 SGK2 SRPK1 KIF27 SHMT2 MOCOS INSRR EPHB1 P2RX2 DNAH14 MPPED2 AOC1 CCT2 DPYS AGK AK8 CYP3A5 NME1 IKBKE AARS2 TTLL4 RUVBL2 MELK DYRK1B KIF23 MKI67 CUL9 SLFN5 HLTF KIF15 PCCB MAP3K13 KIF3B BUB1 TOP2A CCT5 AURKA MYO10 ATR LARS2 SMARCAL1 KIF2C MCM7 COASY ABCC5 TTLL12 PRKDC RHOBTB3 SGPL1 GCAT HELB RAD54L PKM SBK1 EIF2AK1 PHKG2 KIF11 PASK MCM3 PEX6 MCCC2 TARS2 CHD6 EGFR DNAH8 LIG1 SARS2 RIPK4 MORC2 ABCB6 CHEK1 NEK11 ASS1 ACSF2 KIF3C EPHA10 PFKP ABCB9 HSP90AB2P MST1R KCNJ11 KHK AKT2 OXER1 PKMYT1 DNAH11 BRIP1 DDR1 CAD BLM PPP5C ATAD3C GLE1 ERCC2 TRPV4 MYO1A TRIT1 RECQL5 DYRK2 DDX56 PPIL1 MARK1 TNIK IKBKB DCLK1 TTBK1 CBWD6 FASTK NSF DDX51 MB HARS2 PAK1 LRGUK CDK1 CDK12 DNAH6 EPHA1 LRP2 PPIC KIF5A UCK2 MERTK STK32A CCT3 ATP2A1 TTLL9 TNK2 GOT2 NAV2 OAT DHX37 TRAP1 ABCC11 SYN3 MAP3K10 KIF19 DNA2 ACTR3C KIF2A DHX33 ACSBG2 KIF7 ITPKA KSR2 PDK1 NEK5 ACTR3B METTL3 SMO MYO5B AK7 ATAD3A DNAH5 PRKAA2 ABCA4 UCKL1 PSMC4 RTCB RECQL4 MAST1 ACVR1B STK11 TEP1 ITPR3 ULK1 DHX34 HSPA4L NMNAT2 MYO19 PARS2 MOV10 ANKK1 ILF2 CDK3 ATP7B DCAKD NEK10 NADK2 NFS1 SPG7 DNAH7 DHX40 GALK2 TRMU MTOR GSS DNAJA3 ATP9A AARSD1 LONP1 DHODH TRIO KIF22 MAPK13 RAD51D EPHB2 UBE2Q1 TK1 DTYMK CHTF18 SCN8A KIF21A CSNK1G1 LMTK2 SLC22A5 HSP90B2P GRIN3B MAPK10 TSSK3 XPR1 KIF20B NDUFA13 ASNS GK5 CHD5 CDK13 TTLL10 TWF1 ACSL6 TYRO3 ATAD5 MAT1A ATP13A1 NADSYN1 CCT7 CDC7 IP6K2 YARS2 RAD50 ABCC10 TNK1 EP400 PFAS UBE2O ABCC9 ENTPD8 DGKA IARS2 ERBB3 FTCD TTLL3 ACLY FIBCD1 ENTPD3 ABCC3 PHYKPL ABCA7 FANCM MCM6 MYO5C CKMT2 WRNIP1 DYNC1LI2 KIF21B CDC42BPG PRMT1 SRPK2 DHX8 MCM5 NMNAT1 ZRANB3 DDX23 DYNC2H1 NEK4 LANCL2 SCYL3 CUBN CHRNA3 CYP2D6 ADCK1 PIP5K1A MYH7B PFKFB4 LRRK1 TTLL6 IGHMBP2 MYH3 MAB21L1 MUSK ABCD4 PALM3 PRKD2 STK39 PI4KA GAD1 STK35 CHRNA5 DDX55 ATAD2 FARSA MYH13 ROS1 MSH4 SUV39H2 PMS1 ATP6AP1 MSH2 MAP3K14 ADCY1 SMARCA4 ULK4 STK38 DDX54 ABCF3 RTEL1 CDC42BPA RFC5 CSNK1G2 NME4 PAK4 ICK ABCF2 ACSF3 NUBP2 DNAH1 HK2 BMS1 RAD51 HLCS FARSB STK25 MAP3K9 PFKM NOS1 CHRFAM7A MARK4 SNRNP200 NME7 CHD3 CDK5 POMK ERBB2 NUBPL SMC2 PNKP ADCY6 CENPE HBG2 EIF4G1 GNE SRCAP EARS2 MYO15A DDX52 HSPA7 GLYCTK MTHFD1 TP53 CBWD1 TSSK4 SEPHS1 PAICS TIMM44 SIGMAR1 PPIA EPHB4 UBE2C NPR2 RIPK3 ADCK2 OAS3 PI4KB NAT10 TK2 TTLL5 BRSK2 KIF24 MOK ALPK1 DDX41 MAP3K19 MAP2K2 GRIN1 ACSL5 NLRC5 ERCC3 PRKAG1 ROR2 SLFNL1	up	***
MIR19A_3P	0.0000035	0.0001128	0.6272567	-0.2478310	-1.495162	550	SLC31A2 EREG ABHD5 DLC1 OSBPL11 USP12 KLF13 SECISBP2L ADCY9 NUP54 RAPGEF2 ARRDC4 RCOR1 OTUD1 CCDC88A DDX6 LONRF1 QKI GPCPD1 BMPR2 S1PR1 MEF2A WBP4 EOGT MOB1B CCNL1 ZBTB4 UBL3 HECW2 RAPGEF4 RAP1A NLK KLF10 FOXP1 HIPK3 ADRB1 PLXNA4 MED26 ANKRD29 UBE2D3 RAB14 ATP6V1B2 FBXO8 ATP10A RHOB MTMR6 BNIP2 DENND6A REST SOCS5 KLF7 RBMS1 PDE3B HNRNPUL2 ID2 ARC PNRC1 CCND2 FRMD4A EPS15 CCSER2 ADIPOR2 MBD2 CLIP4 SLC6A6 PRICKLE2 KPNA3 AFF1 FAM76B NCKAP5 CNOT6L SRGAP2C BTG1 CREBRF VAMP3 PDIK1L VPS37A PKNOX1 PHTF2 LRRTM2 SGK1 KIF13A EBF2 SOCS3 APPL1 MAGI2 RAB8B HCFC2 C20orf194 ZFP91 DESI2 HIC1 PDE5A BMP3 RABGAP1 BAG5 ATXN1L SKIL MBNL2 FAM43A KBTBD8 ATL2 GTDC1 HOMER1 ZNRF3 RASSF2 GRSF1 CD164 MSMO1 SRSF6 PPTC7 SLC35F1 MAPK8 TSHZ3 RIN2 FLNC BTBD7 EMC7 ZNF521 SMCR8 TGIF1 ZFYVE9 SBF2 YTHDF2 SKIDA1 ZBTB11 CNOT7 MAP3K2 ATXN1 HBP1 GABARAPL1 NPTN MACF1 PLAA SERINC3 ARPP19 INO80D SYT11 ARAP2 MIER1 WDR1 RTN1 EPN2 VPS4B CYP2U1 SP100 MEX3C BRWD1 G3BP2 RBMS3 LIMCH1 DOCK10 PTEN DUSP7 CAMSAP2 RORA ITCH LDLR C2orf42 DOCK4 NR3C2 WDFY3 DNAJA2 EIF4G2 DMXL2 AFTPH ZFYVE26 MB21D2 SERPINE1 AQP5 CFL2 CLIP1 ZNF385B HIPK1 ATF2 MAPK1 CLOCK CNGA3 DCUN1D3	down	***
GO_PYRUVATE_FAMILY_AMINO_ACID_METABOLIC_PROCESS	0.0008489	0.0112126	0.4772708	0.9900062	1.495062	2	GPT GPT2	up	*
GO_CARDIAC_CHAMBER_MORPHOGENESIS	0.0045087	0.0396450	0.4070179	-0.2991695	-1.494932	107	SMAD6 RBP4 FOXF1 TEK CCM2L TBX3 ENG CITED2 BMPR2 TGFBR3 TGFBR2 HEG1 TBX2 GATA3 FOXC2 TNNC1 ID2 SMAD7 TBX5 HES1 MIR17HG TGFB2 SRF RBPJ	down	*
GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0011014	0.0137062	0.4550599	-0.2810944	-1.494722	176	KMO GIMAP8 TMOD3 MTMR10 CIR1 TET2 FAM49A UBR3 B3GNT5 UBL3 SERINC1 ACOT2 FOXP1 PRSS12 CLN5 SLC25A37 TIPARP PTPN12 PXDC1 SOCS5 PLBD1 ARHGAP9 ARL4A ADD1 AFF3 STK24 TDRD7 HCK NRROS MYLIP CREBRF SOCS3 TYROBP RCAN1 CCR7 FAM43A LPCAT2 CEBPZ SNRK RNF146 FOXO3 DDX18 CD1D CD81 FCGRT CRY1 VPS39 PLA2G15 TXNDC15 ALDH2 NFKBIA TTC28 LPAR6 GIMAP4 RNF13 FEZ2 SPATA13 FCRL1	down	*
REACTOME_ESR_MEDIATED_SIGNALING	0.0037200	0.0343736	0.4317077	-0.2918311	-1.494179	146	EREG GREB1 CAV1 HBEGF GNGT2 HSPB1 CAV2 GATA3 GNG7 AKT3 AGO4 AGO3 CDK9 CTSD EPGN GNAI2 NCOA1 SRF KANK1 AREG EBAG9 JUN PIK3R1 DDX5 CREB1 FOS CALM1 FOXO3 FOSB STRN GNAI1 GNG5 GNB4 KAT2B PPID JUND HSP90AA1 ZDHHC21 CREBBP GTF2F2 SPHK1 KAT5 CDKN1B ATF2 MAPK1 GNG11 POLR2L RAD21 EP300 POLR2B NR5A2	down	*
MIR548AZ_5P	0.0000781	0.0015699	0.5384341	-0.2595660	-1.493588	360	SLC24A4 EREG GCOM1 PPARG ZC3H12C DPYSL2 MBOAT2 BMP2 TMEM170B CITED2 BMPR2 MTMR10 STX11 OTUD4 MOB1B ACER3 ZEB2 KCNAB1 UBR3 EIF4A1 SGMS2 PPP1R15B PAG1 PEX5L PPP2R2A C1orf162 SLAIN2 PPP3CA HNRNPDL TNS1 PDE4D UBE2D3 TXN ADARB1 SCP2 SGTB PPP6R3 LIN7C ADO LEPROTL1 HAUS2 KLF9 STK17B ADAMTS9 SPAG9 NFKB1 AQP4 FRMD4A CAPZA2 WASF3 PIK3C2A CLIP4 SLC6A6 RBM44 KPNA3 CRIM1 NCKAP5 ADD1 NCOA1 C2orf69 TOPORS BTG1 SERTAD2 ETF1 RYBP PDIK1L PHTF2 PLGLB1 APPL1 AQP3 CPEB4 DESI2 RAPGEF1 SKIL CREB1 CXCL5 DENND4A TMEM128 AGFG1 SNX9 CCDC152 PBRM1 TCF4 CHRAC1 DCK CDC37L1 MAP3K2 ATXN1 MICU3 PHLPP2 PITPNA ADAMTS4 EPB41L5 THAP6 ARIH1 BRWD1 GPD1L POLR2M ZDHHC21 TBCEL BCAT1 RNF38 ABCA8 DOCK4 NABP1 SPOPL FEZ2 MIER3 YTHDC1 PLAG1 RBMXL1 CFL2 ZNF106 ATF2 MAPK1 CLOCK ITGB1 SLC38A2 HAS2 NAALAD2	down	**
TGCCTTA_MIR124A	0.0000054	0.0001679	0.6105269	-0.2517082	-1.493428	495	SLC31A2 SEMA6A SASH1 EDNRB OSBPL11 KLF13 EMP2 PTPRE MBOAT2 PID1 EGR2 RGS9 DDX6 LONRF1 MYADM VAT1L RTN3 THAP2 QKI NR3C1 OTUD4 SYNC GGA2 PDE2A EDEM1 SEMA6D SH2B3 NFIX CACNA2D2 TACC1 TTL PCYOX1 LMNA C1orf21 ANXA5 LITAF MED26 AKT3 SPRY2 RAB14 TUBB6 PTPN12 EFCAB14 ROCK2 AHNAK LRRC57 PPP6R3 KLF4 ZCCHC24 PEG3 SLC7A8 MYRIP ABCC4 SNIP1 COTL1 RBMS1 GPR85 CCND2 FRMD4A UBE2B ELK3 ADIPOR2 CUL5 MPC1 OXSR1 ZNF706 KIAA0408 BACE1 TLL1 RSRC2 ZDHHC20 RAB6A MTPN KANK1 MYLIP MYO1C ETF1 VAMP3 SCN4B GZF1 PHTF2 PSEN1 CNTN3 MITF VAT1 KCTD12 GAS2L1 ETS1 DESI2 HIC1 JPH1 RHOG APBB2 FERMT2 SP3 PCGF5 CREB1 MAPK4 SLC10A7 PDZD2 FAM177A1 ITGA11 PPM1F ACSL1 BLOC1S6 CD164 SRSF6 PPTC7 EPHA3 PEA15 BAZ2B DYNC1LI1 HBP1 ANKRD13A NPTN GNA13 MACF1 IST1 RXRA GLTP SLC31A1 OPN3 EPN2 DCTN4 SLC25A20 FBXO30 TOB2 BRWD1 TMEM184B RBMS3 ULK2 TMEM109 LYSMD3 LIMCH1 STK4 PDE4A ARPC5 ANXA11 TMCC3 NRP2 NAA15 IQGAP1 WDFY3 MACROD2 USP48	down	***
GO_TUBULIN_BINDING	0.0008993	0.0117005	0.4772708	0.3139214	1.493272	282	KIF1A KIF12 KLC3 KIF20A MDM1 KIF18B BRCA1 RACGAP1 BRSK1 KIF14 CEP70 PLK1 GAPDH PRC1 DYNC1I1 KIF27 WDR90 NME1 TTLL4 KIF23 KIF15 KIF3B MAP10 CCT5 TPR KIF2C AGBL4 TTLL12 MAP1LC3C PDCD5 FSD1 HOOK1 KIF11 GAS8 KIF3C CLIP3 SPAG8 PPP5C ALDOA TRPV4 PSRC1 NUSAP1 KIF5A CENPJ BIRC5 JAKMIP1 KIF19 KIF2A KIF7 CCDC88C SPAG5 MAST1 VBP1 SPEF1 VPS41 ADNP KIF22 RAD51D DNM1 KIF21A GAS2 S100A9 MAP6D1 KIF20B POLB TRAF3IP1 FTCD EFHC1 CDK5RAP2 KIF21B EML6 TBCA FAM161A STMN3 KATNB1 SKAP1 TTLL6 HAUS4 NEFH STRBP ALMS1 APC2 JAKMIP3 TUBGCP4 SYBU CCDC181 HOOK2 CCDC88B MARK4 AGBL5 BCAS3 CAMSAP3 CENPE MAP1LC3A GOLGA2 DCDC1 MAP9 DNM1L CLASP1 KIF24	up	*
GSE17721_CTRL_VS_POLYIC_4H_BMDC_DN	0.0013843	0.0163078	0.4550599	-0.2851605	-1.493060	166	ZC3H12C CLDND1 SIK1 HCAR2 CAV1 NUDT9 NR3C1 IL1RN MOB1B CCNL1 TXNIP SSTR1 PAG1 ATP10A DAB2 OSTF1 CDKN1A ATF3 CAPZA2 PPP2R5A N4BP1 SPRYD7 CMTM6 TDRD7 PROCR USP25 RAB8B MTMR14 MITF PPP1R15A IRF8 NPR1 BLOC1S6 PIK3AP1 EHD1 GSAP TSC22D1 IFNAR1 ZNF296 PDE4B ETS2 IL18RAP SERTAD1 CEBPD TAB2 ARL14EP G3BP2 FNBP4 KLRK1 TNFSF9	down	*
GSE17721_LPS_VS_CPG_6H_BMDC_UP	0.0015414	0.0176171	0.4550599	-0.2849753	-1.492917	163	SLC12A6 ADPRH RBMS2 LRRC8C SNX10 SLC10A1 FYN CCRL2 SAMHD1 PRPF38A TLCD2 BFAR FAM122A AKT3 ATP10A MAP2K3 TBX4 STX3 LY96 SEC24B ATL3 GPR85 ARL4A KLRD1 PI4K2A SAR1A PHACTR2 APPL1 HSPA1B TSPYL1 SNRK CDK14 CACYBP CD164 CCR4 DOK3 SERPINB1 KCNN2 TMEM70 ACADL CRY1 GNA13 SMAD2 IQSEC1 UBE2D1 FNBP4 STK4 MAFK KLRK1 TNFSF9 BMI1 SUGT1 TNFSF8 CDKN1B ATP11B	down	*
GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN	0.0061285	0.0497847	0.4070179	0.3289221	1.492509	176	NMNAT3 METTL1 GTSE1 ALDH18A1 WDR70 TRIB3 XPOT SIMC1 NOP9 QTRT1 SLC29A2 PDCD5 MRPL3 AIMP2 FAM162A AHCY DCTPP1 PRMT6 PHB ALG3 THOP1 HDGF ATIC KIF2A DHX33 GNPNAT1 NUP205 POLR1C DYNLL2 MYO19 GEMIN5 MAGOHB COPS6 GEMIN6 PPHLN1 RPL7L1 PIGU SURF2 SNRPD1 CLUH HAX1 DUS4L RCC1 SLC1A5 MARCKS NEFH ALG8 BANF1 WDR77 PRPF31 LPIN1 SUPT3H PPIA TBL3 FAM185A PPP1R14B CALU PMEPA1 WDR55 UTP18 CLPP HINT1 TIMM10 NHP2 GLRX5 NPM1	up	*
MORF_AATF	0.0049535	0.0424921	0.4070179	0.3267948	1.492373	184	RUVBL1 EIF2B5 MCM2 CCT2 RUVBL2 SDHA TP53BP1 PRKDC TRRAP AIMP2 ACTL6A PKMYT1 CAD PHB ALG3 COQ9 DYRK2 THOP1 ANAPC5 PABPN1 SSBP1 KXD1 RTCB EIF6 ILF2 MTOR SNRPA SSRP1 MLEC TCEA1 DAP3 DNAJC11 KDM3B PSMD2 COPS6 PSMB3 BRD8 ACLY SRRT MCM5 LSM7 TFAP4 AATF POLR2I SMARCC2 EIF3K NUP62 PRPF31 BMS1 MRPL9 SNRNP200 VDAC3 RPN1 GPN1 PWP1 SART3 PRKAG1 LYPLA1 CLNS1A XPO6 DRG1 NELFB ADSL HUWE1 SAFB CS XRCC5 NAE1 HNRNPAB LRPPRC PSMD3 DHX38 DDX49 FIBP	up	*
GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP	0.0036498	0.0338908	0.4317077	0.3306100	1.492241	167	HELLS MDM1 KCNK5 CEP89 PARPBP PAGR1 GINS1 CDCA2 UHRF1 SLC35E3 EXO1 POC1A BRPF3 MRPL3 TRIM11 BRD9 MRPS11 EEFSEC UQCR11 PSRC1 PPIL2 KIAA0556 ING4 CTDSP2 AAGAB GDPD1 IFT52 RP9 TUBG1 MLF2 TRIM37 DTYMK AGPAT5 LRWD1 KDM3B CCT7 LSM14B ZNF841 CKAP5 BRD8 RPA1 BAD WDR83 CKAP2 POLR2I MRPL51 CREB3L2 WDR27 HDLBP TTC12 SCNM1 DOHH TRAK1 MXD3 PGPEP1 SBNO2 RANBP3	up	*
GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN	0.0022571	0.0234620	0.4317077	-0.2889613	-1.492177	152	CLEC1B FABP4 LPL ARL8B CD9 ATP2B1 RRAGC LMNA ENTPD1 CLEC7A TTYH2 STOM TFRC MTHFR ATP6V1B2 ATP10A AHNAK PTPRO CLIC4 SPAG9 NR1D2 ATF3 CDS2 ATP6V0D2 IL7R CALM2 CNOT6L VWF OASL CPEB4 HK3 MBNL2 GPR183 GAS2L3 PNPLA2 TREX1 TSC22D1 RELL1 APLP2 LGALS3 GABARAPL1 BRI3 ANKRD12	down	*
ELVIDGE_HYPOXIA_UP	0.0053693	0.0451226	0.4070179	0.3334165	1.492148	155	GPR87 CA9 EGLN3 SPOCK1 AK4 ZMYND8 S100A2 PPFIA4 SLC2A1 DDIT4 EFNA3 ANKZF1 HILPDA SOX9 STC2 PRKCA DPYSL4 ALDOC KRT15 TMEM45A ANG YEATS2 FAM162A EGFR PFKP DDR1 NOL3 FLNB SPRY1 IGFBP5 RBCK1 PDK1 ARTN	up	*
GSE3982_MAST_CELL_VS_NKCELL_UP	0.0014106	0.0164724	0.4550599	-0.2849855	-1.492143	166	EPAS1 LIPA LYL1 FCER1A RTN3 FOSL1 ALAS1 LAMP1 SIGLEC6 HSPE1 WWC2 MCTP1 LMNA CAMTA1 ABHD6 EPB41L2 SORBS1 TPSG1 ADO DRAM1 SOCS5 CLIC4 ABCC4 GMPR M6PR ARAP3 RPF1 GNAQ RSL24D1 TBC1D4 SNN FRY PPP2CA ESD PPP6C MITF IPO7 ZNF804A MOB1A RBKS PSMD12 LSM6 TSC22D1 UTP3 SERINC3 HSPA2 CHMP3 LRP12 GLUL BCAT1 TIMP3 P2RX1 CAMSAP2 GRB10 EVI5	down	*
DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	0.0000003	0.0000125	0.6749629	-0.2347625	-1.491950	800	SMAD6 SASH1 SWAP70 DLC1 DENND5A USP12 SECISBP2L ADCY9 RDX RAPGEF2 MBOAT2 LRRFIP1 RCOR1 BDNF FYN KIAA1109 GTF2E2 QKI SRSF7 DYRK1A MEF2A NR3C1 TGFBR3 WBP4 OTUD4 TGFBR2 NFATC3 RFTN1 HEG1 ZEB2 NUMB ARHGAP29 KIAA0355 ATP2B1 PTPRM UBL3 ADAM17 RAP1A PBX3 PICALM REV3L KLF10 KLF6 CAV2 PTX3 EIF4E PPP2R2A FOXJ3 RB1 HNRNPDL ZFYVE16 ZEB1 ITSN2 TCF7L2 UBE2D3 ATP6V1H SETD3 TIPARP ZMIZ1 ADARB1 PTPN12 ROCK2 TLE4 ACSL3 PLAUR ID3 ROCK1 GRK5 SOCS5 KLF7 MYO1B GAPVD1 SPAG9 SEC24B PDE8A NFKB1 DOCK9 RBMS1 CDS2 EPS15 CCSER2 WASF3 DUSP1 PIK3C2A SMAD7 MBD2 PPP2R5C PPP2R5A GNAQ OXSR1 N4BP1 IL7R PAFAH1B1 KPNA3 TP53BP2 AFF1 CRIM1 MARK3 EFR3A NCOA1 TGFB2 STK24 TDRD7 FOXN3 RAB6A RPS6KA2 RBM39 MOB4 RBPJ PPP2CA RYBP BCAR3 NSMAF NEK7 PIKFYVE SEC14L1 SRSF3 C2CD2 JUN MITF RAB31 MN1 DDX17 ARHGEF10 SHOC2 RABGAP1 APBB2 FERMT2 DHX15 IPO7 SNX2 PODXL IFRD1 SP3 ZNF804A FRYL CREB1 MALT1 ATP13A3 HOMER1 AP3B1 UVRAG DLEU2 TUBGCP3 WDR7 AGFG1 SLC25A24 CDK17 HIVEP2 YTHDF3 USP7 FOXO3 PKD2 MAPK8 RIN2 SPOP AZIN1 NUP153 STXBP3 PHF3 TGIF1 PDS5B BAZ2B ZFYVE9 DUSP5 ZBTB11 GNAI1 PIK3C3 NFYC ATXN1 ORC2 PPP3R1 HNRNPH3 CTIF CLASP2 CRY1 MACF1 N4BP2L2 ADAM10 PHLPP2 ME2 MBNL1 ATAD2B PCCA HELZ RNF2 BMP2K ARAP2 ANKLE2 FGF2 NEK1 PDLIM5 TNFAIP8 RLF YAF2 CEP170 CDC16 NBN TFPI NT5C2 ACAP2 TIAM1 PIP4K2A TRAPPC8 EPHA4 TAB2 SIK3 ARIH1 SP100 PSME4 NUP98 CREBBP DAPK1 MAP3K4 NPAT TTC28 GTF2F2 PTEN TMEM87A TLK2 CYTH1 CAMSAP2 ITCH LDLR DOCK4 NRG1 TLK1 WDFY3 PUM1 NUP160 SMAD4 RNF13 EVI5 DMXL2 KLC1 HAT1 ABI1 SETX STARD13 UBR2 SERPINE1 PEX14 CDKN1B CLIP1 ATP11B CENPC ATF2 LHFPL2 CLOCK	down	***
GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP	0.0026161	0.0262156	0.4317077	-0.2810543	-1.491789	180	EREG IL1B SIK1 RTN3 AQP9 STX11 ELMO1 TRIB1 IER2 HBEGF PTX3 HNRNPU MCL1 HNRNPA3 BNIP2 VASP CDK9 CTSD LAPTM5 COTL1 P2RY2 CXCL2 DUSP1 ARL4A CARS2 TP53BP2 ACTR2 AREG CREM SGK1 SOCS3 NECAP1 CTSZ GLUD1 TREM1 PLK3 JUNB PPP1R15A BAG5 PABPC4 CD83 RAB8A SPATA2L YWHAZ ATP6V0D1 ADNP2 MFSD10 FOSB TESK2 FPR2 DUSP5 TSPAN14 NPTN PLEKHO2 JUND CXCR4 HNRNPK G3BP2 SCPEP1 ICAM3 GLUL NFKBIA PAK2 SFPQ EHD4 ATP6V0A1 HERPUD1	down	*
GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP	0.0057436	0.0473968	0.4070179	0.3337407	1.491327	154	C1QTNF6 NUDCD3 SDK2 CDK4 SPP1 SAYSD1 SFXN1 KIAA0895 SHMT2 AP1G2 LMLN LDHB BZW2 CUL9 TSGA10 TIMD4 HAVCR1 FANCD2 MCCC2 ANKRD16 FNTB KLHL3 RECQL5 TRAP1 ANKRD26 NLN GAL3ST4 NET1 MPI CCNE1 AKR1E2 ATP6V0E2 FHIT UBE3D ACBD4 L1TD1 TCEA2 SULT1B1 PFAS ABCA7 NOSIP ZNF563 DPH5 HOOK2 METAP1D PAICS RANBP3 TLR5 CDC25B SFXN5 UBTF NAT10 MRPS26 NELL2 PRKAR1B F5 XPO6 RPL23A LRRN1 PPARGC1B PTPRK PRPF19 PNPO ECE1 TCEA3 PPA1 OLFM2 LRPPRC	up	*
GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP	0.0061661	0.0499978	0.4070179	0.3262975	1.490624	181	SPICE1 KIF20A PKP2 UBE2T KIF18B SORD LYPD6B IFT27 TFDP2 NWD1 CCNF MAP2K6 GINS4 TRIM45 GOLPH3L HMMR KCNN4 PAFAH1B3 CENPL AURKA KIF2C CDCA5 PEX6 LETMD1 KIF3C RPAP2 KNSTRN CDKN2C TMEM106C ZNF260 FAM114A1 GMNN RNF181 DDT RNASEH2A VIPAS39 NADK2 DHX40 KIF22 SLC37A4 ZSWIM3 C15orf41 CEP128 HLA-A ACBD5 KLHL32 ALKBH4 KIF21B CYP2S1 ADD3 GLO1 STK38 SHCBP1 ZNF436 NBR1 MTIF3 MRPL9 NME7 MXD3 BCL6 PAICS TTC9C TMEM38A RASGEF1A	up	*
GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN	0.0027194	0.0269652	0.4317077	-0.2815719	-1.490226	169	RAMP3 OLR1 LTA4H GPR65 CD44 CITED2 IDI1 IL1RN FUCA1 FAM49A SCARF1 RCHY1 CASP9 EDEM1 HSPE1 EIF4A1 HBEGF RAB14 PXDC1 PER2 CDKN1A ITGAX CCND2 PLEKHB2 CD53 ALOX5AP N4BP1 SNX3 ARL6IP5 HCAR3 IL2RB SEC14L1 STAT4 STX7 LYRM1 ZBTB24 NDUFV2 PLCG2 NKG7 DUSP5 NAB1 PIM1 ATXN1 PDE4B ETS2 ARAP2 TNFAIP8 CEP170 PAMR1 TPT1	down	*
GO_RESPONSE_TO_CYTOKINE	0.0000000	0.0000006	0.7477397	-0.2388090	-1.490168	953	GPD1 CXCL3 GPR17 EREG ACP5 KMO CD300LF IL17RB IL1A FOXF1 HMOX1 CXCL16 PPARG IL1B FABP4 MNDA SNX10 DCSTAMP GREM2 PLA2G10 PID1 FYN CD44 PDE1B CCL3L1 SOX17 CCRL2 INPP5K SAMHD1 ST3GAL6 BAG4 CAV1 FOSL1 MYD88 CDC42EP2 SRSF7 PCOLCE2 S1PR1 CDC42 IL1RL1 IL1RN GAS6 OTUD4 PSMD5 CBL SLC11A1 IL23A RHOA PDE2A CD36 ANXA1 MIR146A TNFRSF8 SSTR1 SH2B3 CLCF1 CARD16 FOXA2 ADAM17 LIFR ASAH1 MAP3K8 IFI30 FZD4 LCP1 IFNK ADIPOR1 GATA3 SIRPA IL18R1 TRAF6 NFE2L2 HNRNPDL CRK SFRP1 SPRY2 ZEB1 ARHGEF2 HNRNPU SPI1 TFRC MCL1 MTHFR CD58 PTPN12 IL10 STAT5A CCL22 TLE4 RAB12 FOXO1 BIRC2 EPOR NPNT MEFV CASP1 LIMS1 TNFSF12 YBX3 PTAFR KLF4 CDIP1 TNFSF15 THBS1 CEBPA STX3 SOCS2 CDK9 VRK2 SOCS5 MPL CCL3 LAPTM5 NFKB1 PMM1 CDKN1A ITGAX PTPRC CXCL2 IRAK2 VIM AQP4 AXL CCL4 TLR4 MIR24-2 ACTR3 XCL2 TAF9 FCER1G DUSP1 SMAD7 ADIPOR2 MPC1 OXSR1 IL7R PAFAH1B1 PRDM5 BCLAF1 CA1 PTGIS HLA-DQA1 IL24 AFF3 ACTR2 PIAS1 HCK SRF MYO1C CREBRF VAMP3 CD80 CNTF ELF1 IL6 YBX1 SOCS3 IL2RB APPL1 OASL SRSF3 ETV3 JUN PSMA1 CCDC3 LRCH1 STAT4 ETS1 CARD8 HSPA1B DUOX1 JUNB IFNGR1 JAK1 RAPGEF1 GSTO1 CCR7 SKIL PIK3R1 ACKR3 IRF8 GRB2 CREB1 OSM RC3H1 REL PRKACA DOCK8 CXCL5 TCP1 TNFRSF9 YWHAZ GFPT2 ACSL1 FOS UBB PELI1 KLF2 CACYBP TNFSF13 YTHDF3 PSMD12 FOXO3 MAPK8 TREX1 CD74 ZFAND6 MME CCR4 IRF5 TIMP2 UBXN2A STXBP3 TGFB1 HNRNPA2B1 TEX14 TEC YTHDF2 PDE12 IFNAR1 CD86 IRS2 CNOT7 PIM1 SOD2 CCR1 KYNU PGGT1B SPOCK2 ADAM10 IFNLR1 CCL20 PITPNA JUND CCR6 ICAM1 SELPLG FGF2 IL18 IL18RAP TFPI CEBPD CXCR4 HSP90AA1 CALCOCO2 TAB2 RIPK2 CCR9 HSPA8 SP100 BRWD1 PSME4 TRAF1 DAPK1 NFKBIA KIT TIMP3 EDN1 PAK2 B3GNT2 TNFSF9 AIM2 RORA NRP2 PSMD6 MT2A PSMD9 IL16 EIF4A2 CNN2 SMAD4 SPHK1 IRF2 CSF2 ADAMTS7 LRRC70 UBE2V1 CYBA HTRA2 EGR1 CD70 CSF2RB	down	***
BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN	0.0014136	0.0164724	0.4550599	-0.2862901	-1.489658	154	LIMS2 DLC1 MBOAT2 CAV1 GTF2I HSPG2 ZNF385D PICALM KANK2 PTPN21 AHNAK NOSTRIN ACSL3 AOC3 ZCCHC24 NPR3 RIT1 CADM1 KCNMB1 ZBTB43 ACTG2 MRVI1 NCOA1 ZNF426 C20orf194 PDE5A MSRB3 RABGAP1 RCAN1 FERMT2 ZNF20 TMEM192 LMCD1 FLNC EPHA3 SORT1 SAV1 C1orf116 TGFB1I1 CD81 TAGLN CHMP3 RTN4 PARVA TTC28 COPS8 TIMP3 EMC3 CNN2 STARD13 ENDOD1 CX3CR1 MYH10 FBXW2 ZFYVE1 MTSS1 KIDINS220 SNRPN KATNAL1 DACT3 SEMA5A MAPK7 MYL9 MYLK EXTL2 PTPN14	down	*
GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN	0.0054128	0.0453090	0.4070179	0.3270549	1.489541	180	TRIP13 HELLS CPSF6 GGCT PBK NDC80 TTK GINS1 CDCA8 MCM4 MCM2 ALDOC DTL ZWINT CCT2 KIF15 MRPL15 TOP2A RRM2 FSD1 KIF11 ORC6 MAD2L1 AHCY DCTPP1 BLM CKS1B NUSAP1 TMEM106C CDK1 POLE2 GMNN SNAPC1 PSMB5 FEN1 RECQL4 PA2G4 RNASEH2A ATP9A SSRP1 GINS2 KIF20B CCT7 MCM6 PPCDC SNRPD1 PDIA4 PRMT5 PYCR1 MSH2 CCNA2 VDAC1 GTF3C5 CPOX SMC2 LIF MTHFD1 ENO1 COX17 CALU NCAPH CD38	up	*
MOOTHA_HUMAN_MITODB_6_2002	0.0004407	0.0066426	0.4984931	0.3077714	1.488931	358	CPS1 GPT AK4 BDH1 TSFM SLC25A21 GAL3ST1 MRPL46 NPIPB3 NDUFS6 TOMM34 ALDH18A1 NNT CYP27B1 SHMT2 MRPS35 COX11 NDUFB8 SDHA MRPL15 PCCB CYP24A1 NDUFS2 LARS2 MPO GCAT AKAP1 AMACR OAZ3 ABCB6 MRPS11 ETFA FDXR MRPS30 TST IDH2 SLC25A10 UQCR11 SSBP1 GOT2 OAT ACP6 TRAP1 MRPS2 SLC25A13 MRPL17 PDK1 MRPS12 ETFB MAST1 CPT1B UQCRFS1 ATP7B NFS1 SPG7 MTOR UROS MRPS34 LONP1 DHODH MRPL11 COX7C PPOX TK1 MRPL4 DAP3 NRF1 ACSL6 SLC1A3 COX10 TIMM13 BCL2L1 BAD MRPL24 MRPS33 CKMT2 HAX1 NDUFS7 AMT FARSA PYCR1 NME4 ABCF2 UQCRC1 HLCS COX5B OXCT1 ECHS1 MRPL9 NDUFA8 NDUFS8 CPOX TBCB VDAC3 MTHFD1 SBNO2 TIMM44 MRPS27 PDP1 BCAT2 MRPL20 MRPL48 NDUFB7 COX6B1 DNM1L TK2 COX17 ACAD8 CYP11A1 ACSL5 CYB5B TFB1M SARDH BCKDK POLRMT MRPS16 MLH3 UCP3 DGUOK MRPL12 CRAT CLPP OPA1 BAK1 MRPL2 TOMM40 TIMM10 MPST SHMT1 CS NDUFB2 TXN2 PC COX15 TIMM9 MCCC1 LYPLA2 MTHFD2 COX6A1 FIBP COX6C ABCB8 NDUFA9 SDHC MRPS7 ACADS MRPL35 MRPL13 GATM MRPL33 GSR NDUFA10 BCKDHA MFN1 SUCLG1	up	**
GO_POSITIVE_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION	0.0014136	0.0164724	0.4550599	-0.2861344	-1.488848	154	ANGPT4 EREG ACE TAL1 PECAM1 BDNF FYN CD44 FGF10 NEDD9 GAS6 IL23A CD36 CLCF1 HBEGF ADAM17 ITGA5 WNT3A ARHGEF2 LRP4 PTPRC EPGN HES1 IL24 CD80 CNTF AREG IL6 SOCS3 ADRA1A OSM CD74 TGFB1 TEC CD81 ICAM1 IL18 ARRB2 EPHA4 RIPK2 KIT PAK2 NRG1 IQGAP1 EHD4 BANK1 CSF2 ABI1 GREM1 GHR TREM2 NCF1 IL5 CD3E TNFSF18 CNTN1 CSF3 CTF1 CSPG4 CD4 NTF3	down	*
MIR802	0.0042617	0.0380081	0.4070179	-0.2973967	-1.488507	114	TRIM71 SECISBP2L SNX10 RCOR1 PSMD5 SCARF1 CIT BTG2 ANXA5 HIPK3 CAMTA1 EIF4E TMEM123 SRGN EPM2AIP1 TCF7L2 SCP2 ITM2B ADAMTS9 SOCS2 CALM2 TLL1 RASGEF1B CCNY PHTF2 SLC9B1 TMTC1 ARL6IP6 SLC14A1 EPC1 CREB1 SLC10A7 ZCCHC9	down	*
MIR3960_MIR8072	0.0015874	0.0179896	0.4550599	0.9855653	1.488356	2	SLC9A3 WWP2	up	*
GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP	0.0028148	0.0277182	0.4317077	-0.2803788	-1.488341	178	SLC31A2 ZC3H12C LIPA HCAR2 MYD88 ZCCHC2 ZBTB2 TGFBR2 ACER3 JPH2 ANXA1 PLXNA2 COX18 SERPINB9 NFE2L2 CWC22 FABP5 ZFAND5 MAFG RMDN3 ATF3 HPSE CCL4 IL7R DEGS1 TDRD7 LACC1 NRROS RBPJ SOCS3 OASL SRSF3 ST6GALNAC4 PPP1R15A ENPP4 PCGF5 HSD17B12 CDK14 DDX18 SAV1 TMEM230 NAB1 IFNAR1 CD86 ATP6V0C PLEKHO2 PDE4B PCCA SERTAD1 CDKN1C LRP12	down	*
WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK	0.0033912	0.0321471	0.4317077	-0.2945953	-1.488223	132	PPARG FABP4 LPL PLEKHF2 YPEL5 GINM1 PCYOX1 TTYH2 BFAR STOM FBXO8 ACSL3 FAM49B ABCC4 CD302 ADIPOR2 HSDL2 EFR3A BCAR3 IFNGR1 HSD17B12 PNPLA2 MSMO1 SORT1 CHPT1 AOX1 KAT2B PLA2G15 PCCA PUS10 TOB2 ALDH6A1 G3BP2 FDX1 ACADM MTUS1 LTBP3 CYTH1 TMCC3 NABP1 AFTPH PIM3 KLF15 CHP1 PXMP4 LIN52 DRAM2	down	*
MIR130B_3P	0.0000557	0.0011814	0.5573322	-0.2602822	-1.488118	344	WEE1 EREG DLC1 PPARG SECISBP2L DPYSL2 INSIG1 TRPC3 FYN DDX6 FOSL1 BMPR2 MTMR10 TSHZ1 EOGT TGFBR2 CIT TEX2 HEG1 ZEB2 ZBTB4 HECW2 RAPGEF4 PPP1R15B PEX5L SRSF2 ATP6V1B2 AGO4 RAB12 DGKE NPNT PRKD3 SOCS5 KLF7 SNIP1 ERP44 ARHGEF26 EPS15 PIK3C2A ELK3 MBD2 SLC6A6 CALM2 NRBF2 NCKAP5 BTG1 CCNY TMOD1 PDIK1L VPS37A LRRTM2 KIF13A PHACTR2 APPL1 PIKFYVE HCFC2 HECA BMP3 FERMT2 SNX2 BAG5 KBTBD8 FSD1L CGGBP1 EPC2 PXK ACSL1 AGFG1 UBB PTP4A1 HIVEP2 RUNX3 MSMO1 BTBD7 AKIRIN2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 PLAA SERINC3 MBNL1 ARAP2 LDLRAD4 MIER1 INO80 CEP170 ITPRIPL2 RTN1 RAB5A LRP12 CYP2U1 HSPA8 BRWD1 G3BP2 ULK2 NPAT ING2 CUL3 EDN1 RNF38 CAMSAP2 LDLR NABP1 WDFY3 ZFYVE26 VPS13D MB21D2 CFL2 BHLHE41 CLIP1 ZNF800 MAPK1 DCUN1D3	down	**
GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_UP	0.0022807	0.0236693	0.4317077	-0.2881735	-1.488108	152	ACE LINC00472 CD44 CBL TGFBR2 SCARF1 LRRFIP2 SH2B3 ADA LMNA MTF1 TMEM74B ADRB2 CLK1 MOAP1 AGO3 SRSF5 YBX3 CLDN5 ACTR3 DCP1A CREM SAR1A ADRA1A ELP5 PLK3 ARHGEF10 DNAJA1 IPO7 CASZ1 GPR3 LMCD1 MSMO1 MLANA RXRA PITPNA AMD1 ARIH1 SP100 MEX3C PKNOX2 TMEM87A DLST P2RX1 NRG1 CNN2 CSF2 AFTPH KLC1 MAPK1 ING1 ZYX ECD CDC42BPB FPR3	down	*
GO_NEGATIVE_REGULATION_OF_CELL_POPULATION_PROLIFERATION	0.0000048	0.0001504	0.6105269	-0.2466585	-1.488089	550	SLC6A4 SMAD6 LIMS2 RBP4 EREG ACVRL1 IL1A HMOX1 DLC1 KLF13 PPARG GATA2 SFRP4 SPN WFDC1 IL1B MNDA RAPGEF2 BMP2 CDH5 CCL3L1 CAV1 FOSL1 CDH13 BMPR2 FGF10 PRKAR1A TGFBR3 CD9 TGFBR2 PPM1D TRIB1 APOD MIR146A TNFRSF8 SSTR1 SH2B3 PTPRM CD33 LMNA BTG2 ZNF503 KLF10 CAV2 IFNK DACH1 GATA3 RB1 RGCC SFRP1 SPRY2 BNIPL KANK2 ZEB1 SOX7 BTG3 KRT4 NODAL CNN1 ADARB1 IL10 PTGIR KLF4 REST KLF9 KLF11 THBS1 CEBPA BCHE NPR3 PER2 CDKN1A ID2 MIR24-2 SFTPD DUSP1 RNF139 INHBA PPP2R5C TBX5 ADAMTS8 HES1 MIR17HG IL24 AKIRIN1 PTH1R TGFB2 GNRH1 SRF BTG1 RPS6KA2 RBPJ WNT9A PRKRA CD80 FLT1 IL6 DDX20 PODN MAGI2 ETV3 JUN HPGDS NOTCH1 ETS1 ADRA1A PDE5A TYROBP HSPA1B RAPGEF1 OSM NPR1 RC3H1 MORC3 TNFRSF9 TINF2 PELI1 CD164 RUNX3 PKD2 EPPK1 WNT11 TIMP2 SAV1 TGFB1 PBRM1 STRN PDS5B TGFB1I1 CBFA2T3 LRRC32 CD86 TBRG1 CNOT7 SOD2 MEIS1 MYOCD TOB1 KAT2B TSPO IFNLR1 SMAD2 NR2E3 VASH1 CGRRF1 SF1	down	***
E2F_03	0.0041615	0.0372589	0.4070179	0.3210140	1.487710	206	GRIA4 CDC45 GPAT2 PRRT2 CDCA7 AGFG2 E2F8 NABP2 CDC6 PLD5 E2F3 GAPDH MCM4 MCM2 CDC25A ORC1 CAND1 EPHB1 RANBP1 MELK PAQR4 AP4M1 KNTC1 SEZ6 POLA2 CACNA1G MCM7 PRKDC MCM3 LIG1 TOPBP1 DNAJC9 DCTPP1 TRMT2A PKMYT1 OSBPL7 CBX5 GMNN E2F1 UNG EZH2 LRRC56 DNMT1 ZNF687 FANCG INTS7 CCDC151 PCSK4 ANP32E DNAJC11 RHD POLD1 MARCKSL1 NR6A1 SASS6 KLHDC3	up	*
GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP	0.0056880	0.0470661	0.4070179	0.3282961	1.487700	175	RUVBL1 CPSF6 MND1 PBK GINS1 CEP70 E2F3 SLC35E3 MYBL2 CLCN2 KIAA0895 HAUS5 EXO1 NUP155 TMEM132A CLSPN LIG1 ORC6 CENPO FADS2 MGAT4B SLC25A10 CCDC40 DHRS13 ZNF229 NCAPG2 TMEM106C ANAPC5 CENPH ARPC1A ABHD17C SLC25A13 ANKRD26 ETFB ATAD3A UQCC2 SPEF1 TELO2 ILF2 TRIM24 NADK2 SNRPA DTYMK GINS2 C12orf73 PSMD2 MAGOHB RAD50 PFAS STOML2 ACLY ASRGL1 MCM5 SNRPD1 HAX1 AATF	up	*
GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN	0.0022248	0.0232485	0.4317077	-0.2805082	-1.487674	182	ACE LTA4H PTP4A2 BMP2 RUNDC3B BACH1 CDC42EP2 FAM49A IGSF6 ABCB1 TXNIP SLC44A2 RAP1A IFI30 SPIRE1 HLX PAG1 PTPN12 CASP1 PLAUR ST3GAL2 NR1D2 CD53 ELK3 MPC1 IL7R TBC1D4 DEGS1 CD300LB CNOT6L CLN8 ARL6IP5 PHTF2 GLUD1 RAC2 RAPGEF1 GPR183 ENTPD4 NDST1 CDK17 NAPG NIPA2 VAMP4 TEC	down	*
GO_PATTERN_RECOGNITION_RECEPTOR_SIGNALING_PATHWAY	0.0025493	0.0257471	0.4317077	-0.2838541	-1.487045	157	CD300LF FCN1 SCIMP CAV1 MYD88 MARCO OTUD4 RFTN1 CD36 MIR146A CLEC7A TNIP3 RNF125 TRAF6 UBE2D3 BIRC2 SLC46A2 LY96 UBQLN1 IRAK2 TLR4 SFTPD CTSS APPL1 SEC14L1 HSPA1B PRKCE UBB PELI1 PIK3AP1 SMPDL3B NLRP6 PIK3C3 ARRB2 RTN4 TAB2 RIPK2 UBE2D1 HAVCR2 TLR10 NFKBIA ITCH PUM1 UBE2V1 CYBA EPG5 CLEC4E S100A8 UBE2N BCL10 HMGB1 IRF1 MAP3K1 RAB11FIP2 IRF4 PJA2 LRRC19 UBE2D2 PUM2 MFHAS1 TANK ANKRD17 PTPN22 UBC UNC93B1 GPS2 CYLD CASP8 WDFY1 RIOK3 TLR3	down	*
MIR548T_5P	0.0000381	0.0008627	0.5573322	-0.2583113	-1.486859	356	SLC24A4 EREG GCOM1 PPARG ZC3H12C DPYSL2 MBOAT2 BMP2 TMEM170B CITED2 BMPR2 MTMR10 STX11 OTUD4 MOB1B ACER3 ZEB2 UBR3 EIF4A1 SGMS2 PPP1R15B PAG1 PEX5L PPP2R2A C1orf162 SLAIN2 PPP3CA HNRNPDL TNS1 PDE4D UBE2D3 TXN ADARB1 SCP2 SGTB PPP6R3 LIN7C ADO LEPROTL1 HAUS2 KLF9 STK17B ADAMTS9 SPAG9 NFKB1 AQP4 FRMD4A CAPZA2 WASF3 PIK3C2A CLIP4 SLC6A6 RBM44 KPNA3 CRIM1 NCKAP5 ADD1 NCOA1 C2orf69 TOPORS BTG1 SERTAD2 ETF1 RYBP PDIK1L PHTF2 PLGLB1 APPL1 AQP3 CPEB4 DESI2 RAPGEF1 SKIL CREB1 CXCL5 DENND4A TMEM128 AGFG1 SNX9 CCDC152 PBRM1 TCF4 CHRAC1 DCK CDC37L1 MAP3K2 ATXN1 MICU3 PHLPP2 PITPNA ADAMTS4 EPB41L5 ARIH1 BRWD1 GPD1L POLR2M ZDHHC21 TBCEL BCAT1 RNF38 ABCA8 DOCK4 NABP1 SPOPL FEZ2 MIER3 YTHDC1 PLAG1 RBMXL1 CFL2 ZNF106 ATF2 MAPK1 CLOCK ITGB1 SLC38A2 HAS2 NAALAD2	down	***
GSE19923_E2A_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP	0.0018272	0.0199311	0.4550599	-0.2825497	-1.486717	168	CXCL3 ZC3H12C F2RL3 CLDND1 CD44 CITED2 FOSL1 IDI1 HMGCR BCL2A1 TEX2 NUMB HBEGF EIF1 SERPINB9 SRGN IL10 CFD SLC12A4 RBMS1 CCND2 M6PR SH2D2A ACTG2 CLN8 BTG1 AREG IL6 ST6GALNAC4 EEA1 PRKCE HSD17B12 AGFG1 MSMO1 MAPK8 TGFB1 MIA3 TBRG1 KCNA3 CCR1 ADPGK SOD3 GEM TRAF1 PALD1 FDFT1 LDLR FNBP1 PIM3 DUSP6 HMGCS1 CYP51A1 IL5 TES PAXBP1 FNDC3A ATF6 PLA2G5 CFLAR CCNC TTC39B CASP3 EMP1 KLRG1 CYTIP SQLE SRP19 NRAS ANKRD17 PTPN22 MAPK6	down	*
PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7	0.0003129	0.0050619	0.4984931	0.3081012	1.486491	346	ALDH3B2 PRR15 PRLR FAM201A PTGES CDC45 PARPBP S100A2 CCDC34 SOX2 CYP2J2 COA1 DNAJC22 PHF14 TFF3 CREB3L4 C6orf141 E2F8 IFT122 HILPDA ASPM MMP1 TOMM34 SIX1 FIGNL1 ANKRD22 STC2 MCM4 PRKCA TYMS CA12 GALNT10 MIS18A B4GALT4 EPS8L1 TJP3 CLDN1 KIF15 IGF2BP2 RHNO1 HOMER3 MYO10 HOXC6 CMBL KIF11 FANCD2 LMNB1 MCCC2 THYN1 KIF3C RAD51AP1 MST1R TST MGLL GPX8 PLOD2 EPHA1 NCAPG STEAP1 SDCBP2 EZH2 SAPCD2 RECQL4 TSPAN1 RNASEH2A NET1 SNX27 ZNF233 GPR68 MNS1 S100A16 HMGN3 RBM12B FBXO4 DTYMK IL15RA GINS2 SAP30 FXYD3 ESR1 CEP128 HLA-A CLTB TCEA2 CDC7 CENPV CENPM WDR34 ENTPD3 ANXA9 ADD3 SRSF1 LRCH4 LRIG1 RCC1 HAUS4	up	**
GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0014005	0.0164080	0.4550599	-0.2795597	-1.486413	175	OLR1 MCOLN1 CLDND1 INSIG1 QKI TBC1D2 HPS5 EDEM1 B3GNT5 BZW1 NR4A1 PDE4D DIABLO ZMIZ1 ATP6V1D MAFG SPAG9 GGTLC1 CXCL2 PLEKHB2 ADIPOR2 FKBP15 SNN GPBP1 RBPJ HCAR3 RYBP DDHD1 RAB8B HCST ARL5B STAT4 SH3BP5 NSMCE2 MALT1 SIGLEC15 REL RBKS RUNX3 SAV1 ZBTB1 CTNNAL1 GALC CRY1 ZNF267 ICAM1 TNFAIP8 SLC31A1 ARHGAP18 TXNDC11 G3BP2	down	*
GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0017371	0.0191685	0.4550599	-0.2791394	-1.485621	177	ARHGAP31 TMEM126A PTPRE PPP4R1 MYADM AKAP7 ELMO1 IL1RL1 CD22 PDE2A LATS2 RAP1A FAM89A HSPB1 KLF10 LCP1 TIPARP IL10 ARRB1 ADO GCHFR SHE M6PR TM6SF1 PLEK PPP2R5A PEAK1 VAMP5 UBASH3B ACTR2 SLC25A33 S1PR4 CHDH CD48 NXPE3 ATXN1L GLIPR1 COBLL1 TBX21 RNF146 CD74 CCR4 SERPINB1 TEC LGALS3 STX12 SESN1 IL18	down	*
GSE3982_BCELL_VS_BASOPHIL_DN	0.0018531	0.0201623	0.4550599	-0.2823042	-1.485425	168	ABHD5 SLC12A6 RTN3 CD9 FUCA1 DDO PILRA DPEP2 SERINC1 PBX3 NLK SIRPA UBE2D3 CST3 FBXL5 BST1 FAM124B RNFT1 DRAM1 MAP1LC3B DENND3 MYRIP TLR4 DUSP1 SMAD7 ADIPOR2 PPP2R5A CRIM1 ACTR2 FRY ELF1 NECAP1 RAB31 BMP3 GSTO1 PSTPIP2 RASSF2 CST7 UBB PTP4A1 MBP FOXO3 BIN2 CHPT1 ITGA9 GLRA3 TOB1 SERINC3 ETS2 SELPLG WDR1 TPT1 LRP12 PLGRKT GLUL CD3G ARPC5 FOXJ2 C21orf91 DAZAP2 GRB10 CREG1 LPAR6	down	*
GO_CYTOKINE_MEDIATED_SIGNALING_PATHWAY	0.0000014	0.0000524	0.6435518	-0.2436394	-1.484999	608	CXCL3 GPR17 EREG CD300LF IL17RB IL1A HMOX1 PPARG IL1B GREM2 FYN CD44 CCL3L1 CCRL2 SAMHD1 BAG4 CAV1 MYD88 S1PR1 CDC42 IL1RL1 IL1RN GAS6 OTUD4 PSMD5 CBL IL23A CD36 ANXA1 MIR146A TNFRSF8 SH2B3 CLCF1 CARD16 ADAM17 LIFR MAP3K8 IFI30 FZD4 LCP1 IFNK ADIPOR1 GATA3 IL18R1 TRAF6 HNRNPDL CRK ZEB1 SPI1 MCL1 IL10 STAT5A CCL22 FOXO1 BIRC2 EPOR CASP1 LIMS1 TNFSF12 PTAFR CDIP1 TNFSF15 CEBPA STX3 SOCS2 VRK2 SOCS5 MPL CCL3 NFKB1 CDKN1A ITGAX PTPRC CXCL2 IRAK2 VIM AXL CCL4 MIR24-2 XCL2 FCER1G ADIPOR2 OXSR1 IL7R PAFAH1B1 CA1 HLA-DQA1 IL24 PIAS1 HCK CREBRF CD80 CNTF ELF1 IL6 SOCS3 IL2RB APPL1 OASL PSMA1 CCDC3 STAT4 CARD8 HSPA1B DUOX1 JUNB IFNGR1 JAK1 RAPGEF1 GSTO1 CCR7 PIK3R1 ACKR3 IRF8 GRB2 OSM PRKACA CXCL5 TCP1 TNFRSF9 YWHAZ ACSL1 FOS UBB PELI1 TNFSF13 YTHDF3 PSMD12 FOXO3 TREX1 CD74 CCR4 IRF5 TGFB1 HNRNPA2B1 TEC YTHDF2 IFNAR1 CD86 IRS2 CNOT7 PIM1 SOD2 CCR1 IFNLR1 CCL20 PITPNA CCR6 ICAM1 FGF2 IL18 IL18RAP CEBPD CXCR4 HSP90AA1 TAB2 RIPK2 CCR9 HSPA8 SP100 BRWD1 PSME4 TRAF1 NFKBIA KIT EDN1 PAK2 TNFSF9 AIM2 RORA PSMD6 MT2A PSMD9 IL16 CNN2 SMAD4 SPHK1 IRF2 CSF2 UBE2V1 EGR1 CD70 CSF2RB GHR TNFSF8 SPPL2A	down	***
GSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN	0.0014005	0.0164080	0.4550599	-0.2791667	-1.484324	175	SEMA6B SC5D CLIC3 SECISBP2L PTPRE RASAL2 CAV1 CITED2 MEF2A MARCO IL1RN IGSF6 IL23A CCNL1 NUMB RBM7 TNFRSF8 CLCF1 SBDS NDUFAF7 SERINC1 NDEL1 TFEC BTG3 BNIP2 PAFAH1B1 SPRYD7 MAFF SRF RPS6KA2 MYLIP ETF1 FLT1 WASF2 SYNPO2 INO80C HSD17B13 SOCS3 SNAP23 PLEKHA3 MTMR14 HSPA1B GRASP LGI4	down	*
GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_DN	0.0013016	0.0156063	0.4550599	-0.2791340	-1.484297	176	KLF13 HHEX QKI PLEKHA1 CIR1 HMGCR FXYD2 PDCL MCTP1 RAP1A C1orf21 ZBTB8A CCNI AGO4 MTMR6 TCP11L2 CPVL LEPROTL1 ALOX5AP N4BP2L1 ZDHHC20 STK24 BTG1 FRY CCNY SNAP23 HECA ARL5B STAT4 ZNF597 RNF146 YPEL2 ING3 ZFAND6 TBRG1 KANSL2 CXCR4 SSH2 TBCEL ACADM PAIP2 MT2A IL16 RSU1 HERPUD1 NCF1 FAR1 MT1E PIAS2 WAC DR1 RAB1A UFSP2 ANKRD44 IVNS1ABP ZCCHC14 FAM107B	down	*
HALLMARK_P53_PATHWAY	0.0022528	0.0234341	0.4317077	-0.2798668	-1.484272	182	IL1A HMOX1 PTPRE BMP2 BAIAP2 CDH13 FUCA1 PPM1D RCHY1 TXNIP HBEGF ADA GM2A BTG2 IFI30 SLC7A11 STOM RB1 ZNF365 PDGFA CASP1 KLF4 DRAM1 CEBPA CTSD PMM1 CDKN1A RRP8 ATF3 CCND2 DNTTIP2 CDKN2AIP PROCR BTG1 NINJ1 JUN NOTCH1 PLK3 AK1 PPP1R15A NUDT15 SLC3A2 FOS FOXO3 TGFB1 CCP110 OSGIN1 TSC22D1 CD81 TOB1 RXRA SESN1 CGRRF1 IER5 EPHA2 ISCU S100A4	down	*
GO_POSITIVE_REGULATION_OF_HEMOPOIESIS	0.0037436	0.0345418	0.4317077	-0.2839583	-1.484098	162	CD101 TAL1 GATA2 DCSTAMP GAS6 TGFBR2 TRIB1 IL23A RHOA ANXA1 ADA KLF10 HLX GATA3 RB1 TRAF6 ZMIZ1 EVI2B SOCS5 MPL PTPRC AXL ID2 INHBA IL7R NCKAP1L CD80 JUN ETS1 TYROBP HSPA1B ATXN1L CD83 CREB1 MALT1 AP3B1 FOS RUNX3 FOXO3 CD74 TGFB1 ZBTB1 CD86 CCR1 N4BP2L2 IL18 RIPK2 NLRP3	down	*
GSE3039_NKT_CELL_VS_B2_BCELL_DN	0.0014125	0.0164724	0.4550599	-0.2802424	-1.483132	172	CXCL3 IL1B EMCN HCAR2 CCRL2 LDB2 CAV1 FOSL1 AQP9 SLC15A3 SCN5A B3GNT5 EMILIN2 CRTAM ZMIZ1 CPED1 CSRNP1 SORBS1 DAB2 KLF7 CDKN1A RBMS1 CCL4 PNRC1 ELK3 SMAD7 LYAR IL7R TP53BP2 MAFF PROCR SLC25A33 RBP7 CD80 RNF149 ADRA1A TREM1 APBB2 WTAP STX7 PCGF5 TEC IRS2 SOD2 LGALS3 BRI3 ETS2 ARPP19 SERTAD1 EPHA2 MAFK EDN1 SKI CYTH1	down	*
GO_CELL_SURFACE	0.0000012	0.0000431	0.6435518	-0.2401427	-1.482468	669	TNR SIRPB1 SIGLEC11 AJAP1 RAMP3 ACVRL1 IL17RB FCN1 TEK ACE PECAM1 ADTRP GPIHBP1 CD55 SFRP4 SPN DCSTAMP WNT4 P2RY1 EMP2 CLDND1 BTNL9 RAMP2 THBD BMP2 TRPV2 CDH5 GPC5 ENG PCSK9 FOLR1 LPL CD44 CCRL2 FCER1A CLEC12B CDH13 BMPR2 ADCYAP1R1 C5AR1 S1PR1 FGF10 TGFBR3 MSLN IL1RL1 CD1C CD9 DSCAML1 LAMP1 CD22 TGFBR2 SCN5A ABCB1 CD8A HEG1 CD36 ANXA1 CD5 HBEGF ADA CD33 ARSB ADAM17 LIFR ABCG2 CLEC7A ITGA5 CLEC14A PICALM ANXA5 FZD4 ABCG1 ANPEP SLC7A11 MS4A1 SIRPA TMEM123 ISLR2 TNS1 CD93 SFRP1 WNT3A HNRNPU TFRC PDGFA KRT4 CD58 LRP4 GLDN SLC46A2 MSLNL AOC3 PLAUR THBS1 ADAMTS9 MPL CLIC4 ABCC4 ERP44 ITGAX PTPRC AQP4 SELL SELP AXL JAM2 TLR4 CD53 FCER1G CLEC9A KLRD1 VAMP5 IL7R BACE1 PROCR NRROS KCNA5 CD8B VAMP3 CD80 AREG PSEN1 IL2RB SLCO2B1 HCST NOTCH1 CTSZ TYROBP DUOX1 FERMT2 CCR7 ACKR3 CD83 CLEC17A RTN4R GRIA1 TNFRSF9 TNFRSF10B TIGIT MCAM CD34 CD151 SLC3A2 MBP CD74 CR1 MME CCR4 SORT1 TIMP2 TGFB1 TMX3 CD1D CD6 VAMP4 TSPAN14 LRRC32 KCNN2 CD86 PDCD1 GLRA1 LGALS3 KLRC4-KLRK1 IGHV3-23 CCR1 FCGRT SCARA5 NPTN ADAMTS15	down	***
GO_RESPONSE_TO_PEPTIDE_HORMONE	0.0000511	0.0011028	0.5573322	-0.2605470	-1.482435	341	EREG LPIN2 TEK EDNRB PPARG HHEX CPEB2 IL1B LHCGR CAT ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL EGR2 INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A TGFBR3 ANXA1 ATP2B1 BTG2 ANXA5 CAV2 ADIPOR1 NR4A1 NFE2L2 NDEL1 CRK EPM2AIP1 ATP6V1H ATP6V1B2 FOXC2 IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 ROCK1 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 GNRH1 BTG1 SLC25A33 PDK4 KANK1 MYO1C ADCY2 AREG SOCS3 APPL1 RAB8B STAT4 RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ CACYBP FOXO3 SRSF6 SORT1 STXBP3 SRSF4 GNAI1 ATP6V1A IRS2 ATP6V0C CRY1 ACTN2 KAT2B JUND ICAM1	down	**
GSE14415_NATURAL_TREG_VS_FOXP3_KO_NATURAL_TREG_DN	0.0021661	0.0228312	0.4317077	-0.2937625	-1.482418	135	CPEB2 IL1B CAV1 ADRA1D YPEL5 NR3C1 SLCO2A1 ZBTB2 ZEB2 KLHL30 LATS2 EIF1 C1orf21 AKT3 C3orf62 CASP1 COQ10B NKIRAS1 CCL4 PNRC1 N4BP2L1 FOXN3 PPIL4 AREG DNAJC27 NKD2 NDNF TBC1D12 CD7 EPC2 KLRC2 BAZ2B VAMP4 GNG5 ANKRD12 RNF2 GEM CDC42EP3 THAP6 MAFK CD3G DNAJB9 AIM2	down	*
NFKBIA_TARGET_GENES	0.0000015	0.0000553	0.6435518	0.2911378	1.482228	888	KIF1A ATP6V0A4 PPM1H NPC1L1 ZDHHC8P1 ENTPD2 CEP72 EPHB3 KRT5 ACY3 GALNT6 C5orf63 B4GALNT4 NEK2 EYA2 SLC9A2 PPFIA4 IQCE JPH3 PBK KIF18B CHRNG GAL3ST1 CHODL PPP1R14D ALDH1L1 IGHJ3P CABIN1 POLE ESPL1 B4GALNT1 TFDP2 PHLDB3 CYP4F11 GALNT10 EIF3B MUC20 GON4L LIG3 ARHGAP40 AOC1 PCDHGA8 ASTN2 WDR90 GSDMB CEP250 PPP1R9A RUVBL2 POLR3A OSBP2 STRA6 CLSTN3 LAMC2 CUL9 COPG1 CYP24A1 FRS2 GPER1 ITGB4 P4HTM SEZ6 SYCP2 DOC2GP MAD1L1 IL12B ABCC5 GALNT9 GNAS-AS1 LIPE BRPF3 NME9 KLHDC4 PKM ENTPD6 BEST4 PASK SLC12A7 WDR60 SLC9A3R1 NEB EPHA10 PFKP TBC1D8 TRMT2A RPAP2 DSCC1 B4GALT7 DDR1 HSF4 RABEP2 TRGV1 PPP5C TMEM178B ATAD3C THPO FLNB TRPV4 MGAT4B SLC25A10 DLG5 DBNDD1 PPP1R37 BTBD2 RECQL5 PES1 THOP1 DDX51 SUPT5H PAK1 KRT18 CROCC SSUH2 PICK1 TNK2 DMGDH JAKMIP1 RBCK1 ABCC11 SYN3 KIF19 LARP1 KRBA1 TTC6 SPAG5 RAB11FIP4 LIPT2 TCTE1 CCDC57 ZNF827 RECQL4 YEATS2-AS1 SUSD4 TEP1 PYROXD2 ELMOD3 ST14 EXOC7 AMPH ADAM12 RBFOX3 EFCAB2 LMNB2 GALNS PLEKHG3 PIGG SPTBN5 LMF1 FBXO15 DNM1 CADM4 DBN1 ENAH URGCP ATG9B HIP1R SPTBN2 PKP4 MAPK10 CLTA DAP3 LIN37 LRWD1 ENOSF1 AHNAK2 TTLL10 ACSL6 SIL1 GALNT7 ELAC2 CNDP2 RAD50 SMURF2P1 TNK1 P4HA1 DHRS1 MDGA1 NAGS CDC20 ANKRD6 NPRL3 KCNIP3 ASCC1 CATSPER2 FIBCD1 ARHGAP22 SH3GLB2 ABCA7 IGFL2 KRT8 ZNF320 TTC34 ADAMTS12 BLCAP ZNF558 EML6 CDC42BPG ZSWIM8 BSN SSH3 IGHJ5 SNAP47 NSD1 RTEL1-TNFRSF6B CYP2D6 LRIG1 STMN3 NDUFS7 NEURL4 LRRK1 CYP4F12 POLR3E SUGP1 SLC41A3 NT5DC2 GAD1 ERGIC3 SH3PXD2B U2AF2 MVP TC2N MST1P2 ESRRB GNAL KLHL7 DOK7 CEACAM5 ALMS1 ENGASE GLIS3 ECH1 GTF3C2 RTEL1 CSNK1G2 STAT6 ACSF3 DLEC1 TRAPPC9 ZFP14 MROH1 KCNQ3 IGHJ6 GRM6 TCF25 CHD3 LRG1 TMEM101 PTPRF ERBB2 ARHGEF39 RAB43 BCAS3 PNKP B4GALNT3 ZSCAN29 FLNB-AS1 FBLIM1 MYO15A CHL1 SRPRB BCAN TIMM44 RANBP3 TAF4 CAPN9 SFXN5 SLC35G1 RIPK3 NPEPL1 RNF144A-AS1 SART1 OAS3 SPATA20 KHNYN STK11IP ZBP1 PTPN13 PPP1R16A FBXL18 CORO1B SPATA33 DLEU7 TPM1 SUMF2 BEAN1 DAZAP1 ZNF740 LINC01088 USP20 PSTPIP1 SLC38A10 MUS81 DYNC1H1 BMF MROH7 ZNF619 MAN2C1 MED15 WDR63 HRAS SIGIRR ZNF598 PCNT ST6GALNAC1 CAMK2G NUDT22 DEPDC5 FOXP2 ZNF276 SMOC1 SH3PXD2A NFE2L1 MEGF11 SLC2A8 TLE2 CTU2 STARD10 TYK2 KRT18P61 RNF40 GAK TPPP3 D2HGDH CXXC1 RUFY1 PCBP4 CACTIN RAB26 SHKBP1 HERC2 GGA3 KEAP1 RETSAT TTC13 RGS3 TMEM175 PC OLFM2 ZDHHC11B CSMD1 KSR1 ANK1 TAOK2 CTC1 UVSSA PPP2R1A KCTD6 KLHL17 EVI5L WDR25 DNAH9 DLGAP2 POLD3 CACNA1A PTPN23 TFAP2C IPO4 SFRP5 VPS4A CAPN1 PNPLA7 RMI2 NDRG4 PPP1R32 ECHDC2 ITPA ACOX2	up	***
GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN	0.0049774	0.0425971	0.4070179	0.3277107	1.482226	171	HELLS HJURP CDC45 MCM10 PMFBP1 DEPTOR UBE2T PRIM2 SORD POLE PLK1 CDCA8 CDC6 TPX2 CCNB2 UHRF1 MCM4 TYMS CDC25A PRC1 DTL MIS18A LSM5 MELK KIF23 CEP55 MKI67 CENPW POC1A CLSPN RRM2 MCM3 LMNB1 IDH2 PARP1 PPIL1 NCAPG2 ASF1B PAK1 CDK1 BIRC5 STEAP3 TNRC18 TACC3 ADAM28 GINS2 PRMT7 LCLAT1 MAGOHB L3MBTL2 ZNF502	up	*
GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_STIM_DN	0.0014125	0.0164724	0.4550599	-0.2800633	-1.482185	172	GPR15 HHEX SOWAHC ZC3H12C CLDND1 EGR2 CCRL2 BMPR2 SLC15A3 STX11 IL1RL1 BCL2A1 SEMA6D ZDHHC2 FAM89A MAP3K8 LITAF SRGN SYNPO KLF4 DRAM1 TMBIM1 ITIH5 HOPX HPSE ATP6V0D2 SHE PLEKHB2 ACTG2 CD80 NSMAF RAB8B EEA1 HSPA13 PTGER2 TNFRSF9 SNX9 RIN2 GSAP TSC22D1 ZC3H12D PDCD1 GABARAPL1 ACADL CCR6 ICAM1 IL18RAP ITPRIPL2 ITGAE S100A4 TMEM87A MMD SAMSN1 EHD4 FCRL1 EXPH5 NR4A2 ENDOD1 NDFIP1 ATP2B4 SKAP2 PPFIBP1 GJB2 TTC39B CASP3 GZMB FAM111A EBI3	down	*
GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP	0.0016216	0.0182877	0.4550599	-0.2830446	-1.481981	166	EPAS1 DLC1 PPARG OSBPL1A CD55 PTPRE KCTD9 FYN GPCPD1 SLC39A8 RBM14 RXFP1 TRIB1 HEG1 C12orf76 STARD4 ASAP1 UBL3 RNF125 DACH1 GATA3 ZYG11B EVI2B KIAA0513 UHRF1BP1L CLECL1 CLDN5 CPT1A FAM102B STAT4 RCAN1 GPR183 RNF146 ENPP6 TEX30 ZFYVE9 CTNNAL1 GNAI1 SMAD2 NFU1 DNAJB9 NRP2 NABP1 MIER3 GPALPP1 DMXL2 DUSP6 SVIL FAM13A-AS1 HIPK1 ZNF677	down	*
GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY	0.0046802	0.0406507	0.4070179	0.3236777	1.481868	187	SCIN KIF18B AVIL MRPL46 CIB1 VILL MRPS35 F2RL1 MRPL15 SPTB KIF2C ERAL1 MRPL3 MRPL27 MRPS11 MRPS30 GLE1 TRPV4 MRPL36 NSF MRPL37 KIF19 MRPS2 MRPL17 KIF2A MRPS12 SPEF1 MRPS34 MRPL11 MRPL52 SPTBN5 JMJD4 SPTBN2 MRPL4 VIL1 MAP6D1 DAP3 GFM2 TWF1 LIMA1 CKAP5 CHCHD1 C12orf65 MRPS23 MRPL24 MRPS33 MRPL28 MRPL41 CKAP2 MRPL53 ADD3 STMN3 KATNB1 MRPL51 MICAL3 MRPL14 APC2 MRPS25 MRPL55 N6AMT1 GADD45GIP1 MRPL9 MRPL21 AURKAIP1 CAMSAP3 MRPS27 MRPL20 MRPL48 MRPS26 SH3GL1 CLASP1 KIF24 APEH PDXP MRPS16 ASPH MRPL12 MRPL43 MRPL2	up	*
GSE20715_0H_VS_24H_OZONE_LUNG_UP	0.0032931	0.0313330	0.4317077	-0.2790847	-1.481618	174	PECAM1 USHBP1 EMP2 TRPV2 CDH5 FIG4 LMO2 TMOD3 CYB5R3 YPEL5 TLCD2 CD36 TBX2 CLEC7A CSRP1 FOXP1 ADRB1 ARHGEF2 PDGFA PPT1 FMNL3 PTPRC SELL CD53 ELK3 SLC6A6 TANC1 ARHGDIB TGFB2 SERTAD2 MYLIP DCTN6 HCST ETS1 RAC2 TYROBP SNX2 PTGER2 CD7 RALB PLCG2 ICAM2 ADPRM SERPINB1 CD6 GNB4 BAG6 RGS2 ARAP2 RNF138 EPB41L5 SCN7A RTN1 CXCR4 CD19 CD3G THEMIS2 NRP2	down	*
GO_VACUOLAR_LUMEN	0.0021891	0.0230066	0.4317077	-0.2935902	-1.481548	135	MNDA LIPA GPC5 CYB5R3 MANBA FUCA1 HSPG2 DNAJC3 MAN2B1 ARSB ASAH1 NAAA GM2A IFI30 PRELP GRN FABP5 PPT1 SDCBP GAA TPP1 CTSD HPSE GCA ACTR2 GLB1 HEXB CTSS VAT1 DAPK2 IDS CAP1 CD74 GALC ORM2 IST1 UNC13D HSP90AA1 HSPA8 NHLRC3 CTSC CD1E CREG1 LYZ SMPD1	down	*
GSE3982_NEUTROPHIL_VS_TH1_UP	0.0025414	0.0257081	0.4317077	-0.2868743	-1.481399	152	SLC12A6 PDLIM2 MIR22HG LRRFIP1 MSRA AGTPBP1 DNAJC3 ASAP1 PLXNA2 RAB33B HLX UBE2D3 MCL1 CCNI SORBS1 KLF4 NPR3 SEC24B CD53 NRBF2 MARK3 ARHGDIB PIAS1 RNF141 LTBP2 RAC2 ATP6V0B SNRK BIN2 BTBD7 BAZ2B APLP2 EXOC1 SLC34A2 PARM1 SEMA4A ACAP2 EXD3 MBD5 KCNK7 DOCK4 RAB2A DCUN1D2 CDC14A USP4 MAPK1 HEY1 LRRC2 SCAF11 CAPZA1 SERP1 OCLM WDR26 SETD2	down	*
GO_REGULATION_OF_CELL_SIZE	0.0015799	0.0179360	0.4550599	-0.2846510	-1.481130	154	TNR SEMA6B SEMA3G SEMA6A SLC12A6 RDX DPYSL2 TRPV2 BDNF SHANK3 BMPR2 RHOA SEMA6D SEMA3B TTL PLXNA4 TMEM123 ISLR2 NDEL1 WNT3A KCNMA1 TRIM46 SLC12A4 AQP4 PLEK IL7R PAFAH1B1 RUFY3 ADD1 MTPN CLN8 SRF	down	*
GO_MESENCHYMAL_CELL_DIFFERENTIATION	0.0007050	0.0096968	0.4772708	-0.2774245	-1.481101	185	SEMA6B SEMA3G SEMA6A TMEM100 EDNRB GLIPR2 IL1B WNT4 BMP2 ENG FOLR1 CORO1C FGF10 TGFBR3 TGFBR2 ZEB2 SEMA6D SEMA3B FOXA2 ADIPOR1 RGCC SFRP1 TCF7L2 FOXC2 TAPT1 SNAI1 SDCBP DAB2 SMAD7 TBX5 PEF1 HES1 TGFB2 RBPJ PPP2CA IL6 NOTCH1 DDX17 DDX5 KBTBD8 WNT11 EPHA3 TGFB1 TGFB1I1 CLASP2 SMAD2 LDLRAD4 EPB41L5 OSR1 SEMA4A RTN4 TIAM1 S100A4 RET EDN1 PTEN FGFR1 NRP2 NRG1 SMAD4	down	**
MIR381_3P	0.0000301	0.0007069	0.5756103	-0.2560964	-1.480486	382	USP12 EMP2 GPR65 PTPRE RAB3C BDNF FYN SEC22C CORO1C HEATR5B QKI BMPR2 GTF2I P2RY13 NR3C1 VAPA PPM1D IER2 SEMA6D CLCF1 UBL3 PPP1R15B CAMTA1 PEX5L ZNF697 SLAIN2 FOXJ3 PPP3CA ATP6V1H KDSR CWC22 EFCAB14 MAP2K3 FOXO1 SGTB SORBS1 MPEG1 ACSL3 KLF4 ITM2B CADM1 AXL PNRC1 ACTR3 MATN2 GNAQ KIAA0408 PAFAH1B1 KPNA3 HES1 RABGGTB CNOT6L USP25 RBPJ CREBRF RYBP PHACTR2 PPP6C PDE5A JPH1 EPC1 ELOVL7 IPO7 FYTTD1 SKIL MBNL2 MALT1 RC3H1 REL CGGBP1 TMEM128 AGFG1 PTP4A1 HIVEP2 SLC4A5 BTBD7 ZNF521 ATG2B ZBTB1 PDS5B CEP76 KHDRBS1 CNOT7 HBP1 ORC2 GNB4 CRY1 GNA13 RIMKLB PHF2 ARAP2 PDLIM5 SCN7A RTN1 ARIH1 PTCH1 ULK2 MBD5 LYSMD3 NFKBIA CEPT1 SCAI B3GNT2 KIF1B RORA ITCH RHOT1 ZFPM2 EIF4A2 NUP160 RAB2A YTHDC1 ABI1 PSIP1 KALRN ZNF800 LIN52 CLOCK FUS MYH10 XPO7 TRPM7 UBE2W WNT5A WAC MTSS1 AKAP12 TES PAXBP1 ARHGAP44 ZFYVE21 NR5A2 ITGA6 ORC4 NKTR RAB11FIP2 PLCB4 EDIL3 FNIP1	down	***
GSE5679_RARA_AGONIST_AM580_VS_AM580_AND_ROSIGLITAZONE_TREATED_DC_DN	0.0020201	0.0215940	0.4317077	-0.2793388	-1.479929	173	ACP5 GCOM1 ST8SIA6 DENND5A HVCN1 PLA2G10 ST3GAL6 SFR1 S1PR1 TXNIP ANXA1 CD5 HBEGF LMNA ENTPD1 LAIR1 AKT3 LRP4 SOCS2 PDE8A HOPX SHE ARHGAP9 KLRD1 MATN2 FXYD7 IL7R PIK3R5 ADD1 FAM102B S1PR4 DCTN6 RHOBTB2 PIK3R1 OSM GRASP TBX21 KLF2 NKG7 IFNAR1 FCGRT ADPGK CRY1 IL18 TDRP DOCK10 KLRK1 KIF1B C21orf91 USP48 ARHGEF18 NCF1 FAM53B MTSS1 TES RCBTB2 ITGA6 FAM78A DUSP22 CD226 CFLAR IRF4 GZMB TPST2	down	*
GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP	0.0020086	0.0215213	0.4317077	-0.2812495	-1.479875	168	EPAS1 LPIN2 SWAP70 SPN SNX10 CD44 MYADM IL1RL1 GNPTAB ZEB2 ANXA1 C1orf21 ZDHHC2 SERPINB9 LAIR1 SIRPA IL18R1 MPHOSPH6 BAG1 PTPN12 AHNAK CTSD ITGAX VIM HOPX ID2 DSTN MTPN CD80 GABARAPL2 PHACTR2 RAB8B PLK3 IFNGR1 DAPK2 COBLL1 TBX21 SLC25A24 CALM1 KLRC2 PIK3AP1 SMPDL3B GSAP GABARAPL1 HINT3 NPTN GEM IL18RAP SEC61B ARHGAP18 USH2A SCPEP1 RORA THEMIS2 MIS18BP1 PMAIP1 TSTD3 ENDOD1 CX3CR1 ITGAL ITGB1 MICAL1 HMGN2 BSG	down	*
GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_DN	0.0020086	0.0215213	0.4317077	-0.2811694	-1.479454	168	SMAD6 RBP4 CTSW MYADM TBXA2R TGFBR2 SEMA6D RBM7 KLHL30 CNST B3GNT5 GM2A AHRR ABCG1 HERC3 EPB41L2 STAT5A NRARP MPEG1 FBXL3 MGAT4A ST7L NR1D2 RECK PIK3C2A KLRD1 DSTN TBC1D4 TP53BP2 AKIRIN1 ZDHHC20 RPL17 PDK4 RNF149 SGK1 ADAMTSL2 MAP4K4 TMPRSS11D GRASP CGGBP1 EPC2 TSPAN14 PLSCR4 STON1 GRK4 SLC43A2 PDLIM5 THAP6 PARVA JMJD1C PDE4A RORA	down	*
ZBED4_TARGET_GENES	0.0019269	0.0208236	0.4550599	0.3136622	1.479261	248	KIF20A MND1 PHF14 IFT122 DGCR8 UQCC1 FAM220A AP4M1 TSGA10 CLHC1 NUP155 POLD2 MCM7 LPIN3 MORN1 CMBL CDC25C GET4 TRMT61B MDM2 SPC24 DDR1 PIGO TERC NUSAP1 HARS2 CENPJ AAGAB SLC16A13 SEC61G KXD1 LIPT2 TSPAN1 ZKSCAN5 IRF6 EFTUD2 ZNF687 PARS2 CAPS2 TAPBPL PSMA5 MNS1 MAN1B1 MBD4 S100A16 MLEC SOX2-OT GEMIN5 CD27-AS1 IQCH LTBR YARS2 NIF3L1 CCDC137 PWWP2A BRD8 DGKA HMGB3P22 KRT8 ANKIB1 KPTN RPP38 LRRC46 MST1P2 RER1 HEATR5A PDAP1 AP001372.2 RAD51 ZNF384 UQCRQ C1orf159 DNAJC14 ADAM15 MRPS27 CYSTM1 NELFA DCAF11 PI4KB STK11IP DDX41 TEX9 NDUFAF6 WDR55 SFXN2 DHDDS MRPS16 MLH3 SH3RF2 TRIM52 DFFB CRB3 PNPO	up	*
GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_4H_UP	0.0021940	0.0230394	0.4317077	-0.2840807	-1.479145	161	CD52 SOWAHC SNX10 PTPRE LYL1 LDB2 CYB5R3 NCF2 PLA2G7 MAN2B1 BMP1 SLC7A7 ENTPD1 CHRNE PPP1R15B BTG2 ANXA5 LCP1 SPI1 EPB41L2 HIF3A FUT7 ZFAND5 VASP NPR3 COTL1 ITGAX CD302 ARHGAP9 CD300C DSTN CLIP4 ANXA3 SLC8A1 RNF149 PDE6B JUN GRB2 RBM22 CD74 NR2C1 SBF2 CD81 RGS2 PDE4B RTN1 SEMA4A MFAP5 TRAF1 KIT MAFK PAK2 ITCH	down	*
MODULE_181	0.0042852	0.0381782	0.4070179	0.3234468	1.478918	186	RIBC2 TP63 ENTPD2 POM121L9P FAT2 NRG2 FUT3 ECE2 GTSE1 PROC TBX19 CYP27B1 CCNF HBB RUNDC3A AOC1 CASP2 SMAGP PRB4 SLC29A2 MPO SLC22A18AS B3GNT3 HPR SCAMP5 GAS8 MSI1 ABCB9 GLE1 CLDN9 PIGO RECQL5 EXOSC2 TNFRSF21 JAKMIP1 ALDOB TBX1 CHST3 GALNS PKP3 MAPK13 RAD51D FZR1 ACSL6 MAT1A DNASE1 WNT10B KIF21B GNG4 LRCH4 MYEF2 UNC119B APC2 CDH1 CCDC9 BRMS1 PPP6R2 KCNQ3 MLLT1 ALOX15 TRPM2 PIGL NELFA	up	*
GO_REGULATION_OF_T_CELL_ACTIVATION	0.0005311	0.0077409	0.4772708	-0.2668917	-1.478840	267	SIRPB1 CD55 SPN IL1B FYN CAV1 PRKAR1A CDC42 TGFBR2 IL23A RHOA ANXA1 CD5 ADA MAP3K8 HLX PAG1 GATA3 SIRPA TRAF6 ZEB1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 SLC46A2 CLECL1 SOCS5 FAM49B PTPRC IGFBP2 SFTPD SMAD7 IL7R CYP26B1 HES1 GNRH1 NCKAP1L CD80 IL6 CD160 PDE5A RAC2 CCR7 PIK3R1 CD83 GRB2 MALT1 RC3H1 DOCK8 AP3B1 TBX21 ZNF683 TIGIT PELI1 RUNX3 TREX1 CD74 CR1 CD1D ZBTB1 CD6 LRRC32 CD86 PDCD1 CD81 LGALS3 KLRC4-KLRK1	down	**
GO_POSITIVE_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	0.0048650	0.0418870	0.4070179	-0.2932838	-1.478689	128	CD101 DCSTAMP GAS6 TGFBR2 TRIB1 IL23A RHOA ANXA1 ADA KLF10 HLX GATA3 RB1 TRAF6 ZMIZ1 EVI2B SOCS5 PTPRC AXL ID2 IL7R NCKAP1L CD80 JUN TYROBP CD83 CREB1 MALT1 AP3B1 FOS RUNX3 CD74 TGFB1 ZBTB1 CD86 CCR1 IL18 RIPK2 NLRP3	down	*
GSE25087_TREG_VS_TCONV_FETUS_UP	0.0020462	0.0218271	0.4317077	-0.2790735	-1.478524	173	RAB11FIP1 EPAS1 FBP1 SNX10 RDX DPYSL2 CLDND1 BTNL9 PPP4R1 EOGT TRIB1 STARD4 B3GNT5 ENTPD1 SERP2 TNIP3 SERINC1 MAP3K8 LRP4 AGO4 KLF9 KLF11 SOCS2 ARAP3 PRF1 CMTM6 IL2RB C2CD2 PNPLA8 CACYBP TNFSF13 PKD2 PIK3AP1 LRRC32 IRS2 PIM1 APLP2 LGALS3 KAT2B MBNL1 CCR6 MIR155HG CALHM2 RAB5A TAB2 RBMS3 NEK3 KIT TMEM87A MMD SAMSN1 NABP1 SPOPL TOX2 EVI5 FNBP1 C5 ITGAL ITGB1 ATP1B1 HLA-DRB1 PLN KCMF1 SGPP1 RAD21	down	*
GSE3982_MEMORY_CD4_TCELL_VS_BCELL_DN	0.0015162	0.0173744	0.4550599	-0.2793458	-1.478387	172	ACP5 SIDT2 SWAP70 PECAM1 HHEX CAT COQ2 LY86 LMO2 SLC15A3 HPS5 NUMB GM2A MS4A1 GNG7 RHOB TBC1D9 ADO PIP5K1B YBX3 PAPSS1 ADD1 ARHGAP17 PKIG HESX1 JUN RAB31 STX7 IRF8 COBLL1 CDK14 PLCG2 CD74 SAV1 TFEB TCF4 CD1D PDLIM1 TMEM70 BMP2K OPN3 PARM1 SPIB ALDH2 SCPEP1 METTL7A CEPT1 LYST P2RX1 ZNF165 BANK1 RABGEF1 CTSH BHLHE41 ZNF106 ING1 S100A8 CD79B MAP4K2 PAX5	down	*
MODULE_15	0.0002309	0.0038815	0.5188481	-0.2636183	-1.478362	295	TNR CD52 PECAM1 HHEX GATA2 IL1B LIPA INSIG1 CD44 LMO2 DYRK1A ELMO1 ANXA1 MAN2B1 ADA RAP1A EIF5 ANPEP SLC7A11 LCP1 LAIR1 SRSF2 SRGN TFRC APOC1 CD37 ZMIZ1 PTPN12 EVI2B MAP2K3 SCP2 BIRC2 BNIP2 GPA33 LAPTM5 PTPRC CXCL2 ATF3 SELL HOPX PNRC1 CCND2 M6PR CD53 PLEK VAMP5 HLA-DQA1 MAFF ARHGDIB EMP3 SERTAD2 ARL6IP5 S1PR4 METAP1 NSMAF COPS2 JUN RAC2 PLK3 JUNB RHOG PPP1R15A WTAP GMFG RAB8A TNFRSF10B CLN3 CST7 CD34 PLCG2 FOS PTP4A1 FOSB MME IRF5 TGFB1 SERPINB1 EWSR1 PIM1 ORM2 RGS2 CLEC2B ETS2 ME2 MBNL1	down	**
GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP	0.0035597	0.0333367	0.4317077	-0.2816499	-1.478223	165	PDLIM2 LYL1 AATK AKAP7 MSRA KBTBD3 DSCAML1 TACC1 CYB561A3 RAB14 FBXO8 KDSR FABP5 SCP2 NOSTRIN ACSL3 KLF9 DAB2 STK17B TPP1 FMNL3 LAPTM5 MARVELD1 TEF ARHGAP9 FRMD4A MBD2 SLC6A6 CNOT6L GZF1 CTSS GLUD1 OSBPL9 MTMR9 PALM SNX2 ATXN1L	down	*
GO_SECOND_MESSENGER_MEDIATED_SIGNALING	0.0001481	0.0026718	0.5188481	-0.2595482	-1.478123	314	RAMP3 TMEM100 MCOLN1 EDNRB LHCGR ADCY9 GPR65 ADCY4 RAPGEF2 RAMP2 JPH4 CCRL2 CALCRL CDH13 ADRA1D ADCYAP1R1 INPP5A TBXA2R PRKAR1A RXFP1 CD22 NFATC3 PDE2A CD36 JPH2 MYOZ1 MCTP1 ADA RAPGEF4 NMUR1 CAMTA1 PEX5L ADRB1 PPP3CA ADRB2 PDE4D TMEM38B PPP3CC PTGIR BST1 THBS1 CCL3 PDE3B PTPRC SELP CCL4 PTGER3 UBE2B PLEK ZMPSTE24 HTT GNAQ GNAI2 CALM2 PTH1R S1PR4 SLC8A1 PPP2CA ADCY2 GPR61 NDNF HRH1 ADRA1A PDE5A JPH1 RCAN1 GSTO1 PTGER4 CCR7 ACKR3 PTGER2 NPR1 PRKACA PLCG2 GPR3 LMCD1 CALM1 PKD2 CCR4 FPR2 GNAI1 PPP3R1 CCR1 GNA13 RGS2 CCL20 CCR6 LAT FKBP1A CXCR4 CCR9 MT1M RAPGEF3 ADORA2A EDN1 PDE4A	down	**
GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN	0.0011809	0.0144779	0.4550599	-0.2800231	-1.477455	171	CD300LF SASH1 GLIPR2 SNX10 GPR65 HCAR2 PLEKHF2 LMO2 CCRL2 QKI MSRA MEF2A CASP12 CLCF1 CYP17A1 CHRNE BFAR GPBP1L1 DACH1 KANK2 MTHFR TIMM10B CASP1 MED6 ATF3 MBD2 PIAS1 STK24 HCK SPIN1 BCAR3 STAT4 HMBOX1 STX7 IRF8 GYPC AP3B1 DEDD BLOC1S6 KLF2 RNASEK SPOP CHPT1 BCAS2 SAV1 CCR1 SELPLG EPB41L5 CXCR4 ARHGAP18 RIPK2 TRAF1 KATNA1 FAM13B EHD4 SPATA13 IRF2	down	*
GO_CELLULAR_RESPONSE_TO_PEPTIDE_HORMONE_STIMULUS	0.0004273	0.0064846	0.4984931	-0.2708506	-1.477159	254	LPIN2 PPARG CPEB2 IL1B LHCGR ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A ATP2B1 ANXA5 CAV2 ADIPOR1 NR4A1 NFE2L2 NDEL1 CRK ATP6V1H ATP6V1B2 FOXC2 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 ROCK1 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 SLC25A33 PDK4 KANK1 MYO1C ADCY2 SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ FOXO3	down	**
GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN	0.0044898	0.0395060	0.4070179	0.3267900	1.477088	170	CEP89 PARPBP CENPF KIF18B NDC80 CHODL TTK CDCA2 RACGAP1 ASPM CEP70 CDCA8 TPX2 GUCA1B KIF23 AP4M1 CLHC1 SAE1 KIF2C POC1A HELB GPSM2 PFN2 ACSF2 SLC18B1 IDH2 MNAT1 DYRK2 NUSAP1 CDK1 NCAPG SAPCD2 PLCG1 ANKRD55 CENPP LGR5 VBP1 IFI27L2 ELMOD3 PKP3 ARF5	up	*
TTTGCAC_MIR19A_MIR19B	0.0000079	0.0002286	0.5933255	-0.2518011	-1.476435	442	WEE1 SLC24A4 SLC31A2 EREG DLC1 KLF13 ADCY9 ARRDC4 CCDC88A DDX6 LONRF1 QKI GPCPD1 BMPR2 S1PR1 C3orf70 TGFBR2 SCARF1 CCNL1 ZEB2 ZBTB4 UBL3 HECW2 RAPGEF4 RAP1A RAB33B SPIRE1 KLF10 FOXP1 CAMTA1 PEX5L MED26 HNRNPU ATP6V1B2 FBXO8 ATP10A RHOB DENND6A SOCS5 SNIP1 RBMS1 ARC PNRC1 LBH CCND2 EPS15 CCSER2 ELK3 ADIPOR2 CLIP4 PRICKLE2 KPNA3 AFF1 NRBF2 BACE1 BTG1 MYLIP CREBRF ID4 VPS37A PKNOX1 PHTF2 SGK1 SOCS3 APPL1 MAGI2 RAB8B CPEB4 ZFP91 PDE5A ATP11A MBNL2 FAM43A KBTBD8 ATL2 TRAK2 EPC2 GRSF1 CALM1 PTP4A1 RUNX3 SRSF6 PPTC7 SLC35F1 TSHZ3 RIN2 FLNC BTBD7 AP1G1 TGIF1 TESK2 ZFYVE9 SBF2 YTHDF2 SKIDA1 CNOT7 ATXN1 HBP1 WBP2 ANKRD12 NPTN MACF1 PLAA MBNL1 ARPP19 RXRA SYT11 RNF2 MIER1 WDR1 INO80 CEP170 RTN1 EPN2 PARM1 VPS4B BRWD1 G3BP2 KPNA4 RBMS3 RAB2B KIT RNF38 NRP2 C2orf42 ZFPM2 WDFY3 MIER3 DNAJA2 CBX7 ZFYVE26 MB21D2 CLIP1 ZNF800 NR4A2 HIPK1 LNPEP CLOCK TGOLN2 EFNB2 CCNT2 CD69 DNAJB1 GPR137B WDR47 PDE7B ARHGEF12 FNDC3A MEF2D RNF111 B3GALNT2 WDR26 ITGA6 ROBO2	down	***
GO_RESPONSE_TO_PURINE_CONTAINING_COMPOUND	0.0055719	0.0463382	0.4070179	-0.2922971	-1.476157	129	SLC6A4 GPD1 TEK PPARG IL1B P2RY1 RAPGEF2 THBD TRPC3 INPP5K FOSL1 AQP9 PDE2A RAP1A TMEM38B BIRC2 PTAFR SSH1 P2RY2 SELL PER1 DUSP1 MMP19 SLC8A1 AREG JUN DUOX1 JUNB RAPGEF1 FOS PKD2 FOSB SLC8A3 JUND VGF FDX1 RAPGEF3 ADORA2A PTEN P2RX1	down	*
GSE42021_TCONV_PLN_VS_CD24HI_TCONV_THYMUS_DN	0.0045345	0.0397762	0.4070179	0.3265691	1.476089	170	CEP72 HJURP FANCI ELOVL6 DEPTOR COIL GAL3ST1 GTSE1 NIPSNAP1 ESPL1 SOX9 SPINT2 CA12 C19orf57 B4GALT4 DLG1 FOXA1 CUL9 EMC9 SMAGP HOMER3 DPY19L1 IFI44L TPCN1 ABCC5 AP1M2 MGLL SLC25A10 MB ASF1B BCAS4 FAM114A1 IGSF3 PIGG ZNF768 KRT19 EPB41L4B GALNT7 GTF3C1 USP18 AHCYL1 RPA1 MYO5C CD2BP2 MMP24 CREB3L2 MARCKS ANK3 UNC119B CAP2 SYBU PCSK5 RAD51 FBN2	up	*
GO_NEGATIVE_REGULATION_OF_CELL_DIFFERENTIATION	0.0000053	0.0001646	0.6105269	-0.2441374	-1.476088	545	SLC6A4 TNR SMAD6 DAB1 SEMA6B SEMA3G SEMA6A EREG ACVRL1 SOSTDC1 EDNRB DENND5A TAL1 KLF13 PPARG TBX3 GATA2 IL1B WNT4 RAPGEF2 BMP2 INSIG1 BDNF DDX6 CAV1 CORO1C CTDSP1 FGF10 MIR27B NFATC3 TRIB1 LILRB3 RHOA SEMA6D ANXA1 MIR146A FBXO7 ASAP1 SEMA3B FOXA2 ABCG1 PAQR3 HLX ADIPOR1 EIF4E GATA3 PPP3CA RB1 NFE2L2 SFRP1 WNT3A ZEB1 ARHGEF2 HNRNPU ZNF365 NODAL LRP4 SNAI1 NRARP FOXO1 PTPRO TRIM46 DAAM2 RUNX1T1 REST ID3 ZADH2 ARNTL SOCS5 CCL3 VIM HOPX ID2 TLR4 LBH SMAD7 INHBA TBX5 UBASH3B PAFAH1B1 RUFY3 HES1 AKIRIN1 KREMEN1 TGFB2 GNRH1 SRGAP2C KANK1 MYLIP RBPJ WNT9A ID4 CNTF PPP2CA AREG IL6 YBX1 MED28 PSEN1 NOTCH1 LIMD1 GABPA CUL4A CTSZ CNTN4 BAG5 SKIL IFRD1 PIK3R1 LSM1 RC3H1 RTN4R TRAK2 FSTL3 TBX21	down	***
CREBP1_01	0.0047280	0.0409276	0.4070179	-0.2882805	-1.476001	146	WEE1 RBMS2 MIR22HG LINC00472 CDC42 FBXO3 SH2B3 MCTP1 ZBTB21 ADRB2 GPM6A MAP2K3 AHNAK FAM76A KLF9 USP2 PER2 CADM1 ATF3 CALM2 CRTAC1 CRIM1 ID4 CNTF GABARAPL2 RHOBTB2 MBNL2 CDK2AP2 PREX2 DENND4A CELF2 SPRY4 CALM1 TNFSF13 TREX1 DAGLA TFEB ZFYVE9 TSC22D1 COL15A1 TOB1 PRDM8 SYT11 EPN2 SREBF2 JMJD1C ZDHHC5 PRKG1 FNBP1 STARD13 HERPUD1 CHIC2 AKTIP YRDC WDR47 EP300 ARHGAP44 NFIL3	down	*
MIR4325	0.0005077	0.0074426	0.4772708	-0.2696886	-1.475993	230	KMO DLC1 SGK3 CPEB2 LRRC8C INSIG1 EGR2 RGS9 GTF2E2 CALCRL ZCCHC2 PCOLCE2 DYRK1A NFIX EMILIN2 ITGA5 EIF5 PLXNA4 RAB12 PTPRO BNIP2 REST RRM2B GAA ARNTL MYO1B MYRIP SNIP1 ATL3 TEF UNC5A AFF1 MOB3A FRY SYNPO2 PDCD6IP C20orf194 HELQ ZNF804A KBTBD8 PDZD2 TRAK2 THSD7B YWHAZ ATG3 KLRC2 BAZ2B ACADL NPTN GATA6 PITPNA RTN1 ACTB RBMS3 FNBP4 NHLRC3 JMJD1C RNF38 MMD TMCC3 RORA KLRF1 KALRN BHLHE41 ADAMTSL1 HIPK1 CLOCK SLC38A2 PLXDC2 CCDC93 SCAF11 SGPP1 CHKA ZFYVE21 ROBO2 DOCK5 FNIP1 NR4A3 CCNC SEMA5A SREK1 KLRC1 ADCY3 OTUD7B ZFHX3 ZNF430	down	**
STAT4_01	0.0007243	0.0098885	0.4772708	-0.2706106	-1.475917	214	HSPB7 SOSTDC1 PDLIM2 ODF3L1 HHEX BDNF LPL CITED2 P2RY13 FGF10 ABCB1 ZEB2 ERG SH2B3 UBL3 EIF1 BZW1 HIPK3 TTYH2 NR4A1 PDE4D UBE2D3 FLI1 STAT5A CASKIN2 SDCBP NPNT CLEC1A LEPROTL1 USP2 EPM2A RBMS1 CXXC4 ELMSAN1 PTCHD4 TLL1 FLT1 SGK1 DHH MITF CPEB4 ETS1 RHOJ FYTTD1 GRIA1 PDZD2 LETM2 RHOQ BCL6B RUNX3 RIN2 HNRNPD CPA3 VAV3 DOK3 LRRC32 MBNL1 RNF138 LAT ARPC2 OSR1 RASSF8 JMJD1C EDN1 MTUS1 DOCK4 NRG1 EMC3 FEZ2 GREM1 ZNF385B CLOCK PRKCH SLC38A2 NDFIP1	down	**
GSE20727_CTRL_VS_H2O2_TREATED_DC_DN	0.0021765	0.0229215	0.4317077	-0.2785599	-1.475802	173	SIDT2 LPIN2 FIG4 MEF2A MANBA CD1C CNST ATP2B1 CLCF1 SLC2A14 ZDHHC2 CYB561A3 ABHD6 NR4A1 JAM3 SLC25A37 ARHGEF2 KPNA5 STAT5A SYNPO PPM1K FMNL3 ELMSAN1 HCK BTG1 TBC1D5 CDC40 UTRN ETS1 JUNB IFNGR1 STX7 UBAC2 TNFRSF10B RALB CELF2 PLCG2 STXBP3 TFEB GSAP CD1D HNRNPH3 SPOCK2 TNFAIP8 EPB41L5 ACTB SSH2 SIN3A LYST PSIP1 CRYM-AS1 CRBN TGOLN2 CDC42BPB PTGS1 CD79B CCDC93	down	*
GO_SECRETORY_VESICLE	0.0000007	0.0000274	0.6594444	-0.2364793	-1.475671	744	SIRPB1 SLPI FCN1 OLR1 PECAM1 HVCN1 CD55 IL1B MNDA CLEC3B LTA4H SNX10 CAT RAB44 CLEC12A IZUMO1 RAB3C PTPRB OSCAR BDNF MMRN1 CD44 CTSW CAV1 BAIAP2 CHIT1 CYB5R3 VAMP2 PAFAH1B2 TBXA2R C5AR1 YPEL5 STX11 CDC42 MANBA NCF2 VAPA CD9 FUCA1 GAS6 LAMP1 SLC11A1 LILRB3 FGR RHOA CD36 SLC44A2 DNAJC3 MAN2B1 MCTP1 CD33 ARSB ASAH1 RAP1A GM2A PICALM ANPEP CAV2 PTX3 STOM LAIR1 SIRPA NDEL1 CD93 GRN LAMTOR3 SRGN PDGFA RAB14 CD58 CST3 FABP5 CFD RAB12 EXOC3L1 PPT1 SDCBP BST1 PTAFR PLAUR ROCK1 GAA OSTF1 THBS1 STX3 ATP6V1D MYRIP FAM49B ABCC4 SPAG9 CTSD ATG7 TMBIM1 ERP44 NFKB1 COTL1 ITGAX PTPRC SELL SELP HPSE ARC ARHGAP9 CD53 FCER1G GCA WFS1 DEGS1 ANXA3 BACE1 CMTM6 COPS4 VWF ACTR2 TGFB2 GLB1 HEXB HGSNAT RAB6A NCKAP1L PRCP VAMP3 CTSS PSEN1 PHACTR2 NKD2 EBAG9 SNAP23 RAB8B CYB5R1 CAPN11 VAT1 NOTCH1 RAB31 SFTPB HK3 CTSZ TYROBP HSPA1B ATP11A RHOG STX7 SKIL ENPP4 GLIPR1 GMFG RAB8A SERPINB6 GRIA1 UNC13B CAP1 PRKACA TCP1 FSTL3 CLN3 WDR7 ATP6V0D1 CTTNBP2 PSMD12 ALDH3B1 BIN2 CR1 SYPL2 MME CPA3 TIMP2 STXBP3 SIGLEC14 TGFB1 TMX3 DOK3 SFTPC SERPINB1 VAMP4 FPR2 MTMR2 CDC37L1 TMEM230 TSPAN14 DYNC1LI1 ATP6V0C SLIRP GPR84 APLP2 LGALS3 ORM2 BRI3 STX12 ACTN2 PLEKHO2 CSNK2A2 ADAM10 PDE4B IST1 SYT11 COMMD9 TCTEX1D4 UNC13D	down	***
GO_REGULATION_OF_ANATOMICAL_STRUCTURE_SIZE	0.0000180	0.0004606	0.5756103	-0.2541023	-1.475173	406	SLC6A4 TNR SEMA6B SEMA3G SEMA6A HMOX1 SWAP70 SLC12A6 ACE EDNRB P2RY1 RDX DPYSL2 TRPV2 BDNF SHANK3 TMOD3 BAG4 KANK3 CAV1 MYADM BAIAP2 ADRA1D BMPR2 CDC42EP2 ESAM TBXA2R HMGCR CIT RHOA SEMA6D ATP2B1 PTPRM SEMA3B RILP TTL PICALM SPIRE1 ADRB1 PLXNA4 TMEM123 ADRB2 ISLR2 NDEL1 SPTBN1 WNT3A FOXC2 ROCK2 KCNMA1 TRIM46 PTAFR SLC12A4 ROCK1 VASP PER2 COTL1 P2RY2 KCNMB1 AQP4 ACTR3 CAPZA2 PIK3C2A PLEK DSTN RAP1GDS1 IL7R PAFAH1B1 RUFY3 ADD1 ACTR2 LMOD3 HCK MTPN CLN8 SRF NCKAP1L KCNA5 KANK1 MYO1C SLC8A1 TMOD1 HRH1 ADRA1A PPP1R15A CCR7 IFRD1 GMFG PRKCE GRB2 CREB1 NPR1 RTN4R	down	***
E2F1_Q6_01	0.0037389	0.0345233	0.4317077	0.3193263	1.474939	202	HMGA2 CDC45 CDCA7 E2F8 NABP2 AP1S1 ESPL1 PLD5 E2F3 MCM4 MCM2 CDC25A EFNA5 ORC1 MCM8 RANBP1 CASP2 CCDC150 PAQR4 AP4M1 POLA2 MCM7 CLSPN PRKDC MCM3 TOPBP1 DNAJC9 TRMT2A PKMYT1 CNOT3 CBX5 POLE2 GMNN E2F1 UNG EZH2 RNF207 DNMT1 ACBD6 FANCG INTS7 HIRA DNAJC11 TYRO3 ATAD5 SASS6 PPP1R8 FAF1 MCM6 GNG4 TFAP4 SRSF1 STK35 ATAD2 EIF3K MSH2 YBX2 RAD51 ARHGAP11A KIAA0825 MXD3	up	*
GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP	0.0023486	0.0242070	0.4317077	-0.2772363	-1.474501	184	DPYSL2 SIK1 RTN3 QKI YPEL5 SPCS3 ANXA5 KLF10 HNRNPU FLI1 HNRNPA3 BNIP2 YBX3 KLF9 KLF11 OSTF1 STK17B LAPTM5 COTL1 ATF3 EPS15 MBD2 MAFF AKIRIN1 SEC31A ACTR2 CREM JUN GLUD1 JUNB WTAP PIK3R1 PABPC4 CXCL5 YWHAZ ADNP2 AGPS PTP4A1 USP7 NAPG HNRNPD AZIN1 TESK2 FEM1B DUSP5 TERF2IP TOB1 NPTN HAUS3 IER5 SEC63 CXCR4 ILKAP G3BP2 SCPEP1 GLUL NFKBIA RNF38 PAK2 PTEN DAZAP2 SFPQ DUT ATF4 DNAJA2 PPP1CB	down	*
GO_SIDE_OF_MEMBRANE	0.0000215	0.0005344	0.5756103	-0.2524199	-1.474415	431	PRMT8 AJAP1 AKAP5 STAC FCN1 ACE PECAM1 GPIHBP1 BTNL9 CDH5 ENG PCSK9 FOLR1 FYN SHANK3 CCRL2 CLEC12B CDH13 S1PR1 TGFBR3 IL1RL1 CD1C CD9 LAMP1 TGFBR2 ABCB1 CD8A FGR HEG1 RHOA KCNAB1 CD36 ANXA1 ATP2B1 CD5 ADA CD33 LIFR GM2A ABCG2 GNGT2 ITGA5 CLEC14A ANXA5 LITAF ABCG1 ANPEP CAV2 MS4A1 PPP3CA GNG7 TMEM123 TRAF6 EPM2AIP1 TFRC DIABLO BIRC2 CDIP1 THBS1 ABCC4 PTPRC AQP4 SELL SELP TLR4 FCER1G KLRD1 GNAQ IL7R GNAI2 HLA-DQA1 GNRH1 HCK CD80 IL2RB DNAJA1 PALM FERMT2 CCR7 ACKR3 CD83 RTN4R TNFRSF9 MCAM CD34 SNX9 PTP4A1 PKD2 CD74 CCR4 CD1D CD6 GNAI1 CD86 PDCD1 GNG5 GLRA1 KLRC4-KLRK1 EXOC1 IGHV3-23 CCR1 FCGRT GNA13 RGS2 MR1 CCR6 GEM ICAM1 FKBP1A RAB5A TIAM1 CXCR4 ESYT1 ITGAE CCR9 HSPA8 BCAM TRAF1 CD19 SRMS KIT CD1E CD3G SCUBE1 KLRK1 PTEN CYTH1 P2RX1 LDLR IQGAP1	down	***
GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN	0.0014087	0.0164724	0.4550599	-0.2772744	-1.474409	176	NUP54 CLDND1 BACH1 MYD88 NR3C1 MAP3K8 LITAF TRAF6 TIPARP FBXL5 TIMM10B CASP1 DAB2 ZFAND5 SOCS2 RMDN3 FAM49B NFKB1 SELP CCL4 DNTTIP2 AFF1 RNF149 INPP5B JUN ST6GALNAC4 JAK1 CD83 IRF8 PCGF5 UNC13B AGFG1 PELI1 DCK TEC CD86 PIM1 CCR1 STX12 BMP2K SERTAD1 CEBPD HSPA8 NFKBIA MCOLN2 TNFSF9 MT2A CSF2RB RBMXL1 UBXN8 ZFP36 MT1E IRF1 CUL2 DR1 FNDC3A ATF6 NFKBIZ RNF19B DCAF13 PNP ANKRD17 NOP58 FGL2 ZNF281 GAB1 ID1 PTPN1 TGFBI CCR5 RIOK3 JAK2 IFIT2 UGCG ST3GAL4 GCNT2 MAP3K3 BUD31 IL15 SLC41A1 TRPC1 STAT3 IL17RA DDX24 NAMPT LCP2 YWHAG LYN	down	*
GAL_LEUKEMIC_STEM_CELL_DN	0.0058112	0.0477673	0.4070179	0.3200540	1.474256	196	ONECUT2 KIF20A CDC45 BUB1B CCNB1 KIF18B TUBB2B ALDH1L1 E2F8 GTSE1 AP1S1 PLK1 CDCA8 CENPA ESPL1 CDC6 CCNB2 TYMS CA12 COCH ORC1 LILRB4 ZWINT MAGEF1 MELK HMMR POLM BUB1 TOP2A HOMER3 POLA2 CACNA1G E2F2 RRM2 PASK LMNB1 CDC25C LIG1 FNTB FGGY NUSAP1 ASF1B CDK1 LRP2 BIRC5 E2F1 NCAPG FEN1 FER1L4 ITGA2B TEP1 MAPK13 S100A9 GINS2 PRMT7 ENC1 CADM3 CDC20 PALB2 CENPM CXCL1 THOC5	up	*
BARX2_TARGET_GENES	0.0000000	0.0000003	0.7749390	0.2857431	1.473908	1491	FOXM1 SPATA24 HOXB-AS3 MDM1 FAM81A RUVBL1 CEP89 CDC45 TICRR ZNF273 C1QTNF6 TROAP RPGRIP1L ZMYND8 CHEK2 NEK2 CCNB1 CENPF DROSHA UBE2T GGCT TTF2 CHCHD6 PHF14 MKS1 PLEKHH1 PIF1 BRCA1 C12orf66 CREB3L4 ZNF138 MRPL46 GINS1 ANKZF1 E2F8 IFT122 KIF14 TRAIP ASPM NABP2 STIL NNT-AS1 MSTO1 FLAD1 IFT27 CDCA8 AURKB CENPA ECT2 ACOT8 TPX2 TFDP2 NNT CCNB2 ZNF714 GOLGB1 RAD54B XPNPEP1 CDC25A PRC1 APOL2 TDRKH LIPE-AS1 CAND1 RCCD1 AVL9 ZWINT DZANK1 CCT2 DCTN2 UQCC1 TRIM45 LSM5 ZNF726 NME1 AARS2 GOLPH3L RUVBL2 POLR3A ZSCAN2 BZW2 LTB4R2 RAB11B-AS1 SMARCC1 KIF23 CHAF1A QTRT1 STAP2 EMC9 TP53BP1 AP4M1 BUB1 CCDC77 MSX2 TOP2A EXOC4 CCT5 CENPL RFXANK IQCD NUP155 WDR3 C1orf226 SAE1 GTPBP3 VASH2 TPR KIF2C MCM7 MPHOSPH9 C14orf93 TPCN1 GALNT9 RRM2 LIPE MDFI BRPF3 ZNHIT6 RAD54L ERAL1 BLOC1S1 CDC25C MCCC2 ZNF785 TARS2 RNFT2 LETMD1 CHD6 OAZ3 SARS2 ZNF443 CCDC148 C7orf50 IFT172 ORC6 ACTL6A NFYA PSMD4 RAD51AP1 DNAAF3 TIMM50 SPC24 MRPS11 ZNF48 BRIP1 ETFA FNTB FDXR BLM MRPS30 PHB LRRC45 FADS2 SYMPK C2CD3 FBXO16 CNOT3 ARL16 ALDOA ERCC2 TFCP2 SRRM5 PPP1R37 INCENP CKS1B EFCAB11 ISOC2 C12orf75 FRMD5 CBX5 PAK1 MRPL37 ANAPC5 CDK1 PABPN1 DNAH6 EFCAB6 CCDC61 EXOSC2 LMCD1-AS1 RFWD3 CENPH PICK1 CCT3 NUDT2 ANKRD54 ADAP1 TYW1 POC5 ITGB8 UNG STX18 STAT2 SEC61G PMEL RNF181 BPGM KIF2A ZNF584 PSAT1 ANAPC7 FEN1 TSPAN31 SPAG5 TNPO2 C16orf71 POC1B MRPS12 METTL3 OARD1 TNRC18 LCA5 NAPEPLD TTC16 NOP2 DIAPH3 CENPP SEMA4F ZKSCAN5 KPNB1 CHCHD3 TPD52L2 CHCHD2 HYKK POLR2H GIPC1 LGR5 ZNF687 FANCG UBFD1 CAPS2 ILF2 EDEM3 CEP192 UQCRFS1 CDC23 AKR1E2 DCLRE1C DLGAP5 C19orf44 ATP7B DCAKD NEK10 WDR53 SPG7 SLC26A2 FOXRED1 PSMA5 AGL MTOR ZNF133 SNRPA MNS1 FHIT MBD4 YIPF3 DHODH C19orf12 PLEKHG3 ZMAT5 GPRC5C SUDS3 ACBD4 COPS7B DPH2 TK1 TRAM1L1 PLEKHA8 CENPQ AKAP8L HDAC1 ESCO2 MLEC OS9 CCDC146 MRPL4 ANP32E PKP4 NUDT16 ITFG2 TCEA1 STX18-AS1 BTN2A3P LIN37 SPA17 ZSWIM3 ZSWIM1 NDUFA13 CCDC51 FKBP14 CCDC159 HLA-A PPME1 NAIF1 ELAC2 CCT7 IP6K2 CENPK GEMIN6 LIMA1 CKAP5 CPSF4 L3MBTL2 PWWP2A PSMB3 CDC20 DGKA ORMDL2 PALB2 CENPM WDR34 ZCCHC17 CCDC30 GBF1 C12orf65 RRP9 AP3M2 MRPS23 NOL6 CDR2 ABCA7 CDK5RAP2 MCM6 KDM4B METTL2B WDR83 RPL7L1 MED24 LPCAT4 PRMT1 ZSWIM8 CKAP2 UTP20 MCM5 ANKS3 CD2BP2 TDP1 ZRANB3 SNRPD1 C5orf22 FAM161A SCYL3 ZNF563 HAX1 RAB3D C1orf109 ZBTB9 DOLPP1 POLR2I CYP4F12 CREB3L2 CCNG1 MIB2 RAP2B RSPH4A AP4B1 LRRC46 GOSR2 EIF3K TCERG1 COPZ1 ALG8 SPSB3 PRMT5 ZNF837 ZNF519 MICAL3 AMN1 GLO1 ZNF212 CYTH2 RPS26 RBM42 ULK4 ZNF195 PRDM10 BBX BANF1 TXNL4B PAK4 PDAP1 STAT6 ACKR2 CEP164 WDR77 PRPF31 NUBP2 CAPN10 MAP3K9 NBR1 RNF123 PFKM KCTD21-AS1 NLGN2 ENKUR GTF3C5 MRPL9 SRP9 TYSND1 IKZF4 NDUFS8 ERBB2 NUBPL CPOX TBCB UBAP2L SNUPN ALKBH6 ZNF131 GNA12 BCAS3 POLR1B TARBP2 TCF3 ANKMY2 ZMAT2 ALG1 GGCX MTHFD1 PDZD7 NMT1 HGS TIMM44 TMEM256 ZNF526 UBE2C FBXO45 NCAPD3 SFXN5 ENO1 BTN2A1 PPP2R5D ZSCAN20 TMEM38A MRPL48 SLC39A1 COX6B1 TTLL5 ILVBL FAM222B CALU HEMK1 DDX41 TMEM161A MSANTD4 TRAPPC6A SETD5 ANKRD11 CYB5B RPUSD3 COPE TOMM7 RTN4IP1 XPO6 HEXIM2 RPL23A VPS26B MORN4 PDXP MBTD1 ZNF678 ASB16-AS1 MAP3K12 PDK2 WDR63 SH3RF2 PLK4 UTP18 PTPRK TRAFD1 PRPF19 MST1 TMEM259 TBC1D10B APRT PPP2R5E PNPO FBXO5 PSMB10 ZNF688 HUWE1 CYB5RL MRPL43 ABHD2 TNPO3 FAM111B NFE2L1 FASTKD3 KIFAP3 NSL1 ZKSCAN4 TMPO TOMM40 SLC2A8 ZNF774 TIMM10 SLC4A1AP TRAF7 NHP2 GLRX5 ZNF77 TYK2 RNF8 IMP4 MTMR4 DCLRE1B RNF40 GCSH MTR DLGAP4 OSCP1 HOMEZ RPLP0 MTRR SHB CACTIN IMP3 RBM26-AS1 HINT2 SHKBP1 CS ZNF524 TMEM67 AP2A1 WDR89 RMI1 HNRNPAB TIPIN PC DTX4 FAM149B1 FMN1 AFMID MCCC1 PSMD3 PPP2R1A MTHFD2 DHX38 RPL41 CALM3 SWSAP1 PAN2 EVI5L ELMO2 GARNL3 KLF5 DDX49 HHIP SLC25A35 SLC12A9 SCAND2P	up	***
GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP	0.0021084	0.0223234	0.4317077	-0.2769354	-1.473891	177	CD300LF RAMP2 PDE1B CCRL2 BACH1 VAMP2 STARD4 ATP2B1 EMILIN2 LITAF NDEL1 MAP2K3 FABP5 ZFAND5 ATP6V1D MYO1B SPAG9 LAPTM5 IRAK2 FRMD4A ELMSAN1 HLA-DQA1 RBM39 RBPJ CABLES1 HECA FOXN2 PTGER4 GPR183 FAM43A REL TSPYL1 RGS13 ATP6V0D1 RHOQ PIK3AP1 TGFB1 PEA15 DCK NAB1 CD86 IRS2 RGS2 LAT WDR1 INO80 UBE2D1 TMEM184B LYSMD3 MAFK THRAP3 SNAP29 SAMSN1 PPP1CB CBX7 ATP6V0A1 ZNF800 NR4A2 FTL KMT2E	down	*
GSE557_WT_VS_CIITA_KO_DC_DN	0.0026196	0.0262215	0.4317077	-0.2774423	-1.473748	179	SLPI HVCN1 GLIPR2 CPEB2 LRRC8C STX11 C3orf70 GAS6 TRIB1 RFTN1 ARHGAP29 ASAP1 RASGRP4 LITAF TTYH2 PPP2R2A NDEL1 SRGN DUSP3 CCL22 SORBS1 COQ10B STK17B ERP44 PLEK RSRC2 MAPRE2 NCOA1 LIN54 EMP3 IL2RB SH3BP5 HIC1 DUSP8 SKIL TBX21 ING3 UBXN2A VAMP4 DUSP5 PDLIM1 BRI3 FCGRT GNA13 RGS2 PLEKHO2 IFNLR1 SYT11 HSPA2 SERTAD1 EPN2 RIPK2 ARIH1 ITGAE SCPEP1 VSIG10	down	*
GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS	0.0001543	0.0027649	0.5188481	0.2978171	1.473617	491	CPS1 HKDC1 ENTPD2 AK4 GMDS ELOVL6 NUP107 SULT1C2 GPAT2 PRTFDC1 ACMSD PGM2L1 DDIT4 GUCY2C NMNAT3 THEM4 THEM5 GMPS FLAD1 GPI ACOT8 GAPDH SMPDL3A TYMS UMPS XDH ALDOC GUCA1B PDE9A SMUG1 DPYS AK8 TAMM41 NME1 DNPH1 NUDT1 DLG1 GFPT1 CARD11 IDO1 NUP155 TPR COASY RRM2 NT5C1B NME9 PKM ENTPD6 MCCC2 NUDT17 NME5 ACSF2 AHCY PFKP DCTPP1 CAD GNPDA1 IDH2 ALDOA ENTPD5 PARP1 GCKR LRGUK UCK2 ATIC UNG ALDOB DGAT2 SLC25A13 BPGM GNPNAT1 ENPP3 ACSBG2 PDK1 NUP205 OARD1 AK7 PRKAA2 UCKL1 QPRT EIF6 NMNAT2 MPI UPP2 ACBD6 FOXK1 DCAKD NADK2 SLC26A2 MTOR FHIT MBD4 DHODH TK1 DTYMK NUDT16 AGPAT5 LCLAT1 ACSL6 NUP85 PARP9 NADSYN1 NT5M SULT1B1 RAD50 DHTKD1 SLC26A1 PFAS TSTA3 ENTPD8 STOML2 AAAS ACLY ENTPD3 BAD PPCDC NMNAT1 ACOT11 SLC35A3 PTHLH PFKFB4 LHPP ESRRB NUP62 APOBEC2 ME1 ADCY1 AMDHD2 NME4 ACSF3 ELOVL4 HK2 SEC13 COX5B SULT1A3 PFKM NOS1 NME7 VPS9D1 SLC35B3 PGAM1 SIRT6 ENTPD7 PNKP PARG GMPR2 ADCY6 GNE MTHFD1 NEIL1 PAICS BPNT1 NNMT PDP1 RNLS NPR2 ENO1 NUP210 TK2 NUP93 ACSL5 PRKAG1 APOBEC3B ACSBG1 NOS3 ACSM3 DGUOK SPHK2 PDK2 GSK3A ADSL DPYD APRT HINT1 OPA1 PANK4 PRPSAP2	up	**
MORF_PRKAG1	0.0057293	0.0473096	0.4070179	0.3200664	1.473215	193	NIPSNAP1 EIF2B5 TOMM34 CIB1 RUVBL2 SDHA HLTF TP53BP1 BPHL TPR CDC25C ACTL6A PKMYT1 CAD PHB CNOT3 ALG3 COQ9 MEA1 PABPN1 KXD1 OARD1 RTCB DNAJC7 GOLGA3 FANCG ILF2 MLEC TCEA1 DAP3 SLC4A2 KDM3B PSMD2 COPS6 P4HA1 SH2B1 TSTA3 CPSF4 BRD8 AHCYL1 SRRT MRPL28 TFAP4 AATF NUP62 DOCK3 NFRKB CSNK1G2 BMS1 FBXW11 MRPL9 SNRNP200 RPRD2 CHD3 PARG ADAM15 PWP1 PLIN3 ILVBL SART3 MZF1 PRKAG1 PARP2 CYHR1 XPO6 DRG1 NELFB HUWE1 NSL1 MPST CS LRPPRC UBE3C PSMD3 PPP2R1A PDXDC1 DRAP1 BECN1 CLTC PMM2 RAC1 DDB1 ATXN2L YIF1A PIGC PRKCSH POLR2C SUMO4 CLSTN1 RPN2 HDAC2 NCBP2	up	*
TTGCCAA_MIR182	0.0001599	0.0028395	0.5188481	-0.2664475	-1.473059	277	EPAS1 EDNRB KLF13 RDX INSIG1 BDNF TXNL1 BAG4 CORO1C MYADM CITED2 QKI AKAP7 DYRK1A ELMO1 MOB1B TEX2 NUMB SLC44A2 TACC1 EIF5 RNF144B CAMTA1 FAM122A TAPT1 DENND6A MVB12B VASP MAP1LC3B CEBPA KLF7 EPM2A DOCK9 GPR85 C9orf72 SHC4 ZMPSTE24 CUL5 N4BP1 PAFAH1B1 KPNA3 MARK3 FOXN3 MCMBP VAMP3 ADCY2 WASF2 SNAP23 C2CD2 MITF SP3 MBNL2 IP6K1 SPRY4 FOXO3 ABHD13 CBFA2T3 PCDH17 ATXN1 PPP3R1 TOB1 ADAM10 ETS2 SLC43A2 INTS6 YAF2 PARM1 RTN4 POLR2M RET FAM126B MMD PAIP2 CAMSAP2 DAZAP2 EVI5 STARD13 KLF15 BHLHE41 CLOCK ZFP36 EFNB2 MTSS1 WDR47 KCMF1 PCMT1 ATOH8 DR1 SKAP2 MEF2D	down	**
MIR765	0.0031689	0.0304108	0.4317077	0.3154895	1.472997	219	PRLR PTPRT PCDHGA10 MDM1 XYLB PCDHGA9 PCDHGA5 COL27A1 PCDHGA7 SDK2 GPATCH1 ASIC1 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 CD164L2 PCDHGB6 PCDHGB4 RAD54B PCDHGA11 PCDHGA8 SLC4A8 KAZALD1 LMLN SIPA1L3 RND2 PCDHGA12 PCDHGC5 PCDHGC4 C1orf226 TPCN1 PCDHGA4 PCDHGB7 SDK1 PCDHGA3 ASB16 PML HOXB5 HSPBP1 MYO1A LINGO1 CLMN RUFY4 PCDHGA2 FAM102A DENND1A L3MBTL3 C3orf80 ADAM12 CADM4 FXYD3 ZBTB45 COX10 PCDHGB1 VPS25 ORMDL2 SLC38A7 BTN1A1 RAB15	up	*
GO_CYTOKINE_ACTIVITY	0.0052094	0.0441207	0.4070179	-0.2920781	-1.472610	128	CXCL3 IL1A CXCL16 IL1B GREM2 BMP2 CCL3L1 IL1RN IL23A CLCF1 BMP1 IFNK GRN NODAL IL10 CCL22 TNFSF12 TNFSF15 CCL3 CXCL2 CCL4 XCL2 INHBA IL24 TGFB2 IL17D CNTF AREG IL6 BMP3 OSM CXCL5 TNFSF13 TGFB1 CCL20 FGF2 IL18 EDN1 TNFSF9 NRG1 IL16 CSF2 GREM1 CD70 TNFSF8 C5 WNT5A HMGB1 IL5 TNFSF18 GDF7 CSF3 CTF1 AIMP1 IL32	down	*
GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP	0.0016976	0.0188547	0.4550599	-0.2781728	-1.472179	172	DAB1 CLIC3 OLR1 P2RY1 NUP54 CDH5 TXNL1 CAV1 HMGCR IL1RL1 ABCB1 SH2B3 RRAGC TTL KCNK3 GM2A HDC KIF1C AHNAK SAP30BP PLAUR GRK5 PDE8A CXCL2 PLEKHB2 PPP2R5A PIAS1 GLUD1 ST6GALNAC4 HSPA1B RCAN1 FERMT2 PCGF5 RASSF2 CYP4A22 MOB1A KLF2 MBP DDHD2 VPREB3 GABARAPL1 BRI3 ARPP19 ICAM1 CES3 RTN4 ACADM KIF1B LDLR GSPT1 RNH1 EVI5 CYBA SUGT1 MRPS28 SPSB1	down	*
GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0039694	0.0360357	0.4070179	-0.2804706	-1.472034	165	KLF13 HHEX MBOAT2 HMGCR GNPTAB PARVG HIPK3 KLF6 FAM122A MCL1 AGO4 SCP2 AOC3 GAA STK17B CEBPA MYO15B SELP ARHGAP9 GCA BCLAF1 ADD1 ACTR2 TOPORS PRCP RNF149 CRNKL1 UTRN GIMAP2 TYROBP JUNB DNAJA1 CSTA LPCAT2 TUBGCP3 CST7 PPM1F RELL1 PHF2 MEGF6 KAT2B TSPO ARPC2 HSP90AA1 HSPA8 SCPEP1 SOAT1 METTL7A PSMD9 WDFY3 CSF2RB TMEM30A CX3CR1 NFAM1 SRSF11 IFIT5 XRN2	down	*
MIR3143	0.0000514	0.0011077	0.5573322	-0.2540843	-1.471439	381	RTKN2 AKAP5 MRPS18C ZC3H12C ST6GALNAC3 RUNDC3B KLHL8 EMCN TMOD3 RASAL2 GPCPD1 SFR1 IDI1 NR3C1 SLCO2A1 B3GNT5 LIFR LATS2 PBX3 FZD4 ZBTB21 GLS SLC7A11 DACH1 SRSF2 HNRNPDL SPTBN1 ZEB1 PDE4D SETD3 ZYG11B ATP6V1B2 ATP10A PER3 NRARP MTMR6 SRSF5 LEPROTL1 UHRF1BP1L STK17B MAP1LC3B TMED5 GAPVD1 FBXL3 NPR3 UBQLN1 CADM1 CXCL2 AQP4 ATP6V0D2 ZBTB43 PIK3C2A CNOT6L C2orf69 RAB6A RBM39 CREBRF ID4 PDHX PRDM11 DNAJC27 CTSS PHACTR2 HECA RASSF10 NSMCE2 ARHGEF10 FOXN2 THUMPD1 CREB1 OSM SLC10A7 PREX2 CGGBP1 AGFG1 UBB PTP4A1 FOXO3 CCDC85A IRF5 AZIN1 GOLGA8R HNRNPA2B1 SBF2 GOLGA8H MAP3K2 RELL1 PLSCR4 CSDE1 KANSL2 NRN1 MBNL1 RNF2 BMP2K RBL2 RNF138 RTN1 CYB5R4 USPL1 TAB2 ARHGAP18 NSUN4 OSER1 SCAI B3GNT2 FAM126B GTPBP8 ZFPM2 EIF4A2 SLC44A5 ANO6 GRPEL1 SLC35A1 DMXL2 PSIP1 ACVR1C CHML SPPL2A ZNF800 HIPK1 TGOLN2 C16orf95 SH3GLB1 NOG KMT2E PLXDC2 BBS7 TRPM7 UBE2W PIAS2 VSTM4 UBE2N TRIM13 MATR3 IL5 CRIPT TYRP1	down	**
GSE12366_GC_VS_NAIVE_BCELL_DN	0.0022144	0.0231784	0.4317077	-0.2764232	-1.471165	177	MYO7B SLC12A6 PECAM1 CD55 HHEX GAPT LYL1 SLC25A30 PLEKHA1 TGFBR2 ABCB1 TXNIP MAN2B1 LAIR1 JAM3 CASP1 TNFSF12 ITM2B ITPK1 RBMS1 SELL PNRC1 DUSP1 N4BP2L1 HES1 HEXB EMP3 APPL1 MAML2 LIMD1 CCDC50 IFNGR1 CD83 GPR183 TSPYL1 SLC25A24 KLF2 YPEL2 CR1 TGFB1 VAV3 GSAP MACF1 CLEC2B PDE4B RXRA INO80D CCR6 ARAP2 MOB3B OPN3 ESYT1 DOCK10 SKI LYST IL16 BMI1 CBX7 SETX CHML NR4A2 RAB37 PATL2 CD69 FXYD5 UBE2W	down	*
FOXN3_TARGET_GENES	0.0000002	0.0000101	0.6901325	0.2871733	1.471048	1130	CCNO SIM2 ATP6V0A4 CEACAM1 SLC16A14 HS3ST1 EGLN3 MDM1 FAM182B WFDC3 PKP2 EPN3 C2CD4A PDCD6 ZNF84 HOXD8 LRRC43 EYA2 ARMC3 HOXB6 PAGR1 IQCE TOX3 MKS1 PRRT2 CCDC113 SORD BRCA1 FANK1 PTPRH GPR35 CABIN1 FGF11 NPAS2 BCAS1 TTC26 CDCA8 CCNB2 KNOP1 SMPDL3A PRKCA MYBL2 DNAH3 CKLF-CMTM1 FERMT1 PRC1 HNF4G LIME1 ARHGAP40 ZFP64 DZANK1 CDT1 LRRC27 COX11 UQCC1 WDR90 LMLN SIPA1L3 CEP250 RSPH1 TTLL4 ZNF862 HMMR BTRC MUC6 KIF23 C9orf116 SPAG16 CUL7 EMC9 FOXJ1 TSGA10 FBXW9 MAP3K13 EEF1E1 FBF1 KCNMB3 DPY19L1 THBS4 REC8 SLC2A10 TMEM177 ITGB4 C20orf96 ODF2 SYCP2 CACNA1G LPIN3 SPEF2 RNF157-AS1 ASPHD1 EFCAB12 AKAP1 ANKEF1 ENTPD6 SLC4A11 DCDC2 PASK TRPT1 SNHG11 LINC00511 TGM1 ANG SALL2 SMYD5 WDR60 CCDC148 NEK11 PROM2 ORC6 CKAP2L KIF3C C2orf72 EHHADH TBC1D8 SPATA17 SNORA71D SAMD10 LRRC45 C4orf47 STXBP4 CCDC40 CKLF THOP1 ZCRB1 EXOC3L4 EFCAB11 NRSN2 ETV7 SUPT5H PAK1 KIAA0556 LRGUK LRRC6 PPM1E CEP97 DNTTIP1 SMG1P1 FAT1 DIDO1 ARPC1A GNB1L NUDT2 TTLL9 KIAA0753 ATIC DCBLD1 GMNN DIS3L2 FBXO41 PSMB5 MRPS2 ACTR3C RUFY4 LINC00639 ENPP3 ANAPC7 CPNE1 DYNLL2 MIR3939 SLC35F3 TRAPPC12 TTC16 NLN CBX1 TCTE1 CCDC57 CBFA2T2 SEMA4F FGFR1OP ANXA2R IFT52 KANSL1-AS1 UBN2 EIF6 EFTUD2 HSPA4L DENND6B SPEF1 CAPS2 ZGPAT BBS5 NPHP1 EXOC7 RGS17 ATP7B RABL2A SCLY DTX2 NEK10 MRGBP NFS1 SPG7 COA3 DNAH7 TSNAXIP1 ADNP RBFOX3 ATP9A MNS1 DHRS4-AS1 LLGL2 GALNS COG7 PIGG GPRC5C HIRA IQCG RGS22 HMGN3 RBM12B FBXO15 MORN2 COPS7B ZNF544 NFATC4 ARHGAP5-AS1 CNGA4 POMT2 IQCK HECTD1 HID1 PKP4 TEKT3 ZSWIM3 SLC4A2 ANAPC1 FHL2 SYNGAP1 FUCA2 SND1 TTLL10 C12orf73 NUP85 FBXO44 TRAF3IP1 CLTB TMEM232 AAMP TCEA2 CCT7 RAD50 KDM3A CHPF TMEM234 GTF3C1 UBE2O PPHLN1 KLHL23 KCNB1 EFCAB10 AGBL2 VPS25 AAAS ZCCHC17 CCDC30 EFHC1 DUS1L TCTN1 ZNF497 BCL2L1 USP2-AS1 BAD CDR2 PEX5 MGME1 FAM174A ACTRT3 FAM183A PIGU ROMO1 TDP1 SIRT5 TMEM198 DPY19L2 DYNC2H1 NEK4 FAM161A RTEL1-TNFRSF6B C1orf109 TBC1D16 FBXO36 ZBTB9 RTKN TTLL6 WDR45B RPP38 WDR27 NEDD8 GAD1 LRRC46 OGFR CDH11 U2AF2 PRMT5 ARFGAP1 STRBP SPAG4 B9D1 ALMS1 MAP3K14 TTC12 GRHL1 CAP2 DDX54 RFC5 DTNB USP39 ACSF3 INO80E MLLT6 CARHSP1 STK25 R3HDM4 CHMP1A ARHGAP5 ZNF217 TEPP RUNDC1 KIAA0825 SOX12 CDK5 DNPEP AGBL5 TMEM101 NUBPL LZTS3 CASC2 ENTPD7 GMPR2 C1orf159 EARS2 TRIB2 PGPEP1 ALG1 GGCX MON2 SRPRB NEIL1 MCF2L2 HGS MRPS27 SIGMAR1 CDC25B UBE2C LINC00205 TAF4 FRZB GPN1 ARMC10 NELFA FOLH1 SPATA20 CCDC91 PPP4R4 STK11IP ZNF367 TK2 TTLL5 TRUB2 ATG4B MOK MZF1 PPP1R16A TRAPPC6A PCTP ANKRD13D GEMIN2 SPATA33 SARDH TOMM7 RTN4IP1 PGM5P2 INO80B ATP6V1C2 NDUFAF6 LASP1 DHX57 ARMC2 DNAAF1 ZNF316 ZDHHC1 SLC40A1 SEC31B SHQ1 MAN2C1 VPS16 REXO1 RAB40C MFSD9 RANBP10 GSTP1 PEX11A NUDT22 TBC1D10B ROPN1L PSME1 NFE2L1 LAMA5 RNF175 MECOM KIAA1841 MCEE ZNF414 TCFL5 FHAD1 GLRX5 SCUBE3 CCS LINC00271 CACNB1 SLC2A4RG TASP1 MLLT3 SAMD12 DLGAP4 OSCP1 ALS2 DHX32 CXXC1 ABCD3 KIF6 MRC2 TMEM67 CYB561 CEP112 XRCC5 MTF2 SIX5 GPRC5B CDH24 NCOA5 THAP4 SLC7A6OS E2F4 ZC3H18 TMEM219 HENMT1 HAAO WDR25 SAMD14 DNAH9 POLD3 PIFO PDXDC1 COQ4 TFAP2C IPO4 ZNF839 METTL9 TRAPPC2L HM13 SNHG10 NDRG4 DNAL1 MSL1 RCAN2 SLC4A7 LRBA ZNF460 PPM1G WBP1 SDHC	up	***
GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN	0.0022016	0.0231010	0.4317077	-0.2792621	-1.470455	170	SLC31A2 SASH1 IL1B FIG4 CCRL2 CDC42EP2 BCL2A1 TRIB1 EDEM1 EIF1 MTF1 LITAF ZNF410 SPTBN1 TXN MCL1 EPB41L2 STAT5A PTAFR CEBPA CDKN1A RBMS1 RRP8 PLEK N4BP2L1 VAMP5 SERTAD2 IL6 SOCS3 JUN STAT4 CTSZ JUNB PTGER4 CD83 IRF8 DENND4A RALB UBB HIVEP2 IRF5 JMJD6 DUSP5 PIM1 MR1 GEM ICAM1 TRAF1 TNFSF9 NRP2 DNAJA2 PMAIP1 SMPD1 C1QB ANKS1A EYA3 ZFP36 ATP1B1 CD69 LAMP3 MAN1A1 IRF1	down	*
ONDER_CDH1_TARGETS_2_DN	0.0005082	0.0074458	0.4772708	0.3017193	1.470395	390	COL17A1 SAA1 TFPI2 CEACAM1 GPR87 PTPRZ1 TP63 CA9 PTGES HS3ST1 BIK GALNT14 KRT5 LAD1 EPN3 FAT2 S100A2 GALNT6 LCN2 SLC5A1 ABCA12 MMP1 KRT16 AKR1C1 PAK6 SOX9 CYP27B1 SPINT2 LSR CA12 FERMT1 XDH CYP4F11 PIP4K2C B4GALT4 KRT15 EPS8L1 ITGA2 CLDN1 FAM169A MAP7 KCNN4 LAMC2 STAP2 CBLC TRIM29 ITGB4 TMEM132A AKAP1 HOOK1 SERPINA3 FHOD3 AP1M2 SLC35G2 CD24 RIPK4 B3GNT3 SPINT1 MST1R BACE2 PERP EHF DDR1 INPP4B GRHL2 FLNB WWC1 PTPN3 MARK1 GRB14 KRT18 EPHA1 MCTP2 TNFRSF21 ESRP1 TNFRSF25 STEAP1 GJB3 CDH3 SLC12A8 ARTN SEMA3A TMEM51 IGSF3 TSPAN1 RAPGEF5 IRF6 ST14 CTSV PKP3 MAPK13 IL15RA S100A9 SPAG1 GALNT3 ELMO3 EPB41L4B FXYD3 TMEM30B SLC1A3 DHRS1 LIMA1 ERBB3 CXCL1 TFCP2L1 ERVMER34-1 KRT8 MYO5C LPCAT4 PTHLH CDCP1 OVOL2 ANK3 CORO2A EPCAM GNAL PRSS8	up	**
GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_UP	0.0024111	0.0247214	0.4317077	-0.2775056	-1.470217	173	LPIN2 PPARG IL1B GIMAP8 CTSW CALCRL AQP9 CDC42EP2 MEF2A EPB41L3 ACER3 AVPI1 SPIRE1 FOXP1 AKT3 EVI2B TBC1D9 SRSF5 UBQLN1 UBE2E2 PTPRC RAP1GDS1 GNAQ PTGIS CRIM1 HCK PROCR RPL17 C1QA HPGDS RAPGEF1 CCR7 CD83 UNC13B CD7 LETM2 ICAM2 MAPK8 PIK3AP1 GIMAP1 TGIF1 YTHDF2 CD86 HNRNPH3 TAGAP MEIS1 KYNU CCR6 SFT2D1 B3GALNT1 CCR9 SCPEP1 TMCC3 FAM13B CREG1	down	*
MIR4504	0.0044139	0.0390256	0.4070179	-0.2913117	-1.469891	126	COL25A1 SOWAHC PLEKHA1 RBM7 GM2A C1orf21 RAB33B CSGALNACT2 HIPK3 TBC1D9 KLF7 PLBD1 SEC24B RIT1 ARHGEF26 LBH SLC6A6 BCLAF1 GPBP1 CNTF PPP2CA AREG APPL1 JUN ATP6V0B MAP4K4 WTAP PNPLA8 PCGF5 KBTBD8 TUBGCP3 ACSL1 CDK17 ZFAND6 METTL14 THAP9 MEIS1	down	*
GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP	0.0015429	0.0176171	0.4550599	-0.2763239	-1.469355	176	TSPAN4 SLC47A1 PHYHIP CAT ADCY9 LIPA FIG4 CLEC10A MSRA MAL CD1C IL1RN GAS6 RFTN1 ANXA1 MAN2B1 ASAP1 PBOV1 LMNA PLXNA2 RNF125 RNASE1 PEX5L ADIPOR1 EPB41L2 ZMIZ1 IL10 ARRB1 CCL22 AHNAK KLF11 HTT HLA-DQA1 PI4K2A HGSNAT CREM C2CD2 HRH1 CD83 RASSF2 SPRY4 MCUR1 COL15A1 APLP2 PLEKHO2 PLA2G15 RXRA	down	*
GO_CELLULAR_RESPONSE_TO_PEPTIDE	0.0002116	0.0035925	0.5188481	-0.2566625	-1.469311	310	LPIN2 PPARG CPEB2 IL1B LHCGR ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A CD36 MIR146A ATP2B1 ANXA5 KLF10 CAV2 ADIPOR1 NR4A1 ADRB2 NFE2L2 NDEL1 CRK ARHGEF2 ATP6V1H ATP6V1B2 FOXC2 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 KLF4 ROCK1 KLF11 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 VIM ATP6V0D2 TLR4 PIK3C2A GNAI2 TBC1D4 BACE1 SLC25A33 PDK4 KANK1 MYO1C ADCY2 PSEN1 SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ KLF2 FOXO3	down	**
GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN	0.0014188	0.0165100	0.4550599	-0.2784475	-1.469141	171	CXCL3 CLEC3B RCOR1 KIAA1109 MYADM FXYD2 LAMP1 METTL23 ADAM17 NAAA REV3L SLAIN2 RAB14 PSTK BIRC2 RNFT1 FAM76A TMBIM1 PER2 MARVELD1 PNRC1 RECK EPS15 SPRYD7 BCLAF1 FAM76B NCKAP1L MYLIP DCP1A DDX20 STAT4 ATP11A EPC1 STX5 ENTPD4 CGGBP1 TINF2 USP7 TRAPPC10 STXBP3 TMEM230 MIA3 ATAD2B RNF2 GEM ARRB2 DCTN4 SLC25A20 VPS4B TOB2 HNRNPK ING2 TMX2 ACADM TMEM87A EID1 ETFDH YTHDC1 NAF1 HCFC1R1 ATF2 PDCD2 PLEKHA2 MT1E XPO7	down	*
MIKKELSEN_ES_ICP_WITH_H3K4ME3	0.0001643	0.0029115	0.5188481	0.2948551	1.469084	542	UNC5CL PLAT CA9 KLC3 PTGES MEGF10 DNAH2 LYSMD1 ZMYND8 ARMC3 DNAJC12 WFDC2 CYP2J2 SRGAP3 CHRNG ZP3 ALDH1L1 BRSK1 SPP1 COL7A1 FLAD1 TTC26 GRB7 ALDOC ACY1 GLB1L2 COX6B2 SMUG1 GPX2 ZNF726 GOLPH3L TJP3 C5orf34 PLEKHG1 HMMR BBS1 PON3 C9orf116 TRIM29 CCDC77 EXOC4 TMEM184A MYBPC2 ZNF112 NCCRP1 SLC2A10 RAB19 SMARCAL1 HYDIN TMEM45A CSRNP3 EFCAB12 ADM2 RAD54L CCDC114 PHKG2 NME5 MORC2 RAB13 EHHADH PML FBXO16 ALG3 CLDN9 OSBPL7 RECQL5 TXLNB GPX8 RASSF6 NRSN2 PAK1 CROCC MDH1B ZNF260 TTLL9 GIPR TRIM2 SYN3 GJB3 TCTN2 BPGM ENPP3 FAM186A SEMA3A PBLD GDAP1L1 WDR24 ZKSCAN5 CPT1B QPRT PYROXD2 ZNF454 MPI SPEF1 AKR1E2 COL1A1 DCLRE1C TRIM16 VPS41 TSNAXIP1 NMRAL1 PKP3 ZMAT5 SLC37A4 FBXO15 C9orf152 ZNF239 STOML1 GBP6 SYT1 ELMO3 FKBP14 S100A13 ZNF416 IP6K2 TNK1 KLC4 GEMIN6 PTER LSG1 LIMA1 RIN1 ENTPD3 GMPPA GID8 MED24 RAI14 NSUN6 COL5A3 NOSIP SLC38A7 ZRANB3 C1orf56 ADD3 CYP2D6 EFHB NFE2 NHSL1 ANK3 SH3TC2 MVP SPSB3 AKAP6 PRSS8 PYCR1 AGMAT RCN3 PRIM1 PRR11 TTC12 ECH1 FLRT1 ZNF66 SCNM1 TMEM141 CTU1 PRPF31 ANK2 TOMM40L TEPP TRAK1 WDR49 NME7 FAM83E CPT1C GOSR1 SCN9A ZNF205 NEIL1 PCBD1 FIS1 TMEM256 ZNF681 KRT17 PLIN3 CLEC2D FAM222B ARHGAP8 ACSL5 NQO1 CD38 APOBEC3B SUMF2 CNPY4 ZNF740 TMEM63C CXorf40A WDR63 C7orf25 HRAS MST1 GSTP1 CNKSR1 ZC3HC1 NUDT22 SPRED3 ZNF276	up	**
MIR96_5P	0.0000530	0.0011344	0.5573322	-0.2526896	-1.468897	378	SLC24A4 AJAP1 EPAS1 COL25A1 NOVA2 SLC12A6 EDNRB TMEM52B ATXN3 RAB3C ST6GALNAC3 RUNDC3B TMEM170B AATK PTPMT1 CAV1 VAT1L QKI CTDSP1 PRKAR1A DENND2C RFTN1 ERG EDEM1 SLC44A2 HBEGF CACNA2D2 RAPGEF4 EIF5 LCP1 CLN5 SLAIN2 PPP3CA ZEB1 TCF7L2 TAPT1 MAP2K3 AGO4 PRDM16 FOXO1 KIAA0513 TRIM46 ZFAND5 SLC7A8 STK17B MYRIP FAM49B DOCK9 SHC4 PTGER3 RNF139 PIK3C2A OXSR1 PAFAH1B1 NUS1 LRRC3 CNOT6L TOPORS MCMBP SPIN1 CREBRF VAMP3 DDHD1 NEK7 APPL1 RAB8B MITF VAT1 SH3BP5 C20orf194 PIK3R1 PCGF5 PRKCE GRB2 FAM43A STX5 GRIA1 RALB NDST1 PPM1F MORF4L1 CD164 PTP4A1 FOXO3 EPHA3 SORT1 AZIN1 ABHD13 FEM1B CBFA2T3 MAP3K2 RELL1 ATXN1 HBP1 PPP3R1 RGS2 NRN1 PCCA ARPP19	down	**
MIKKELSEN_NPC_ICP_WITH_H3K4ME3	0.0007264	0.0099045	0.4772708	0.3040588	1.468761	347	PLAT MEGF10 LYSMD1 ZMYND8 DNAJC12 SRGAP3 ZNF138 BRSK1 KIF14 FLAD1 TTC26 ALDOC ACY1 SMUG1 ZNF608 ZNF726 GOLPH3L TJP3 C5orf34 HMMR BBS1 CCDC77 EXOC4 GPER1 ZNF112 SMARCAL1 CSRNP3 RAD54L PHKG2 RAB13 SLITRK6 PML FBXO16 ALG3 OSBPL7 KCNJ2 RECQL5 TXLNB GPX8 CDKN2C MDH1B ZNF260 TTLL9 SYN3 TCTN2 BPGM SEMA3A WDR24 ZKSCAN5 SUSD4 ZNF454 MPI AKR1E2 COL1A1 DCLRE1C TRIM16 VPS41 TSNAXIP1 NMRAL1 ZMAT5 SLC37A4 ZNF239 STOML1 PCDH9 SYT1 MAPK10 FKBP14 ZNF416 NIF3L1 KLC4 GEMIN6 PTN PTER LSG1 LIMA1 PLD1 GMPPA ADAMTS12 MED24 RAI14 NSUN6 SRPK2 NOSIP SLC38A7 ZRANB3 ADD3 VCAM1 SPSB3 PYCR1 PRIM1 PRR11 ECH1 SCRG1 ZNF66 SCNM1 CTU1 PRPF31 ANK2 TOMM40L TRAK1 NME7 CPT1C GOSR1 ADCY6 NEIL1 FIS1 TMEM256 ZNF354B ZNF681 LRRC4C CLEC2D FAM222B NQO1 APOBEC3B SUMF2 CNPY4 CDHR4 ACSBG1 CXorf40A WDR63 HRAS ZC3HC1 NUDT22 SPRED3 ZNF276 CBLN3 BAK1	up	**
GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP	0.0032891	0.0313064	0.4317077	-0.2774993	-1.468672	169	CD300LF CD52 ASGR1 KLF13 HHEX IZUMO1 P2RY13 ANXA1 CHMP1B RASGRP4 ITPK1-AS1 HLX SLAIN2 SPI1 UBE2D3 EVI2B SRSF5 HNRNPA3 LINC00877 C4orf33 KCNMB1 RNF139 RSL24D1 CD300LB LIN7A VCPKMT SERTAD2 PRKRA RWDD1 PSMA1 GMFG MALT1 DOCK8 FXYD6 TGFB1 ENPP6 TAGAP GABARAPL1 ZNF296 SMAD2 JUND TPT1 TBC1D1 MEGF9 HNRNPK SSH2 P2RX1 LYZ HERPUD1 SVIL CENPC CMPK1 KBTBD11 PLN ANKHD1 ACTR1A	down	*
GSE24726_WT_VS_E2_2_KO_PDC_DAY6_POST_DELETION_DN	0.0014454	0.0167350	0.4550599	-0.2783464	-1.468608	171	LPIN2 THBD FYN BACH1 BAIAP2 CITED2 MEF2A FBXO3 ATP2B1 MAN2B1 MALAT1 C1orf21 RNF144B ABCG1 ADIPOR1 PPP3CA EVI2B NOSTRIN UHRF1BP1L MAP1LC3B TPP1 ST7L CDS2 TM6SF1 PEAK1 TM9SF2 MAPRE2 NCOA1 GLB1 ARHGAP17 SNAP23 RGS18 NDNF CD48 NOTCH1 APH1B YPEL2 BAZ2B TEC FCGRT GNA13 GPX3 PDLIM5 MIER1 CGRRF1 RTN4 HIGD1C SSH2	down	*
VART_KSHV_INFECTION_ANGIOGENIC_MARKERS_UP	0.0046542	0.0405211	0.4070179	-0.2906702	-1.468395	132	ANGPT4 CXCL3 RAMP3 HMOX1 TEK PECAM1 ROBO4 SFRP4 IL1B TIE1 ENG CALCRL S1PR1 HEG1 TMPRSS6 WNT2B FZD4 PDGFA IL10 PLAUR CXCL2 HPSE SH2D2A MMP19 BTG1 FLT1 IL6 GRB2 NPR1 CXCL5 TNFSF13 EPHA3 TIMP2 TGFB1 COL15A1 IL18 EGFL7 CXCR4 EPHA4 TIMP3 PTEN FGFR1 NRP2 NAA15 FLT4 SPHK1 EFNB2 PTGS1 HEY1 CALR WNT5A ANGPT2	down	*
RFX1_02	0.0036906	0.0341507	0.4317077	0.3146059	1.468259	217	WFDC3 GRIN2D LYSMD1 ANKFN1 SEMA4B TSHZ2 PTPRR CCDC74A DAW1 AP1S1 LAMP5 RGS6 E2F3 NBR2 CCDC74B MPPED2 OSBPL2 BBS1 SPAG16 QTRT1 TP53BP1 TSGA10 HYDIN CSRNP3 MGAT4B NRSN2 LRRC6 PPM1E CRB2 PICK1 AAGAB E2F1 STX18 REEP6 TCTN2 ITPKA CHCHD3 C3orf67 ANKRD45 SPEF1 THNSL1 DHX40 TSNAXIP1 AARSD1 POLL MORN2 NFATC4 SPTBN2 MAPK10 ZSWIM1 ZNF768 CHD5 KDM3A STRN4 L3MBTL2 STOML2 AP3M2 BAD SH3GLB2 TBC1D16 TMEM17 SCNM1 PAK4 CCDC181 ANK2 TNKS1BP1 NOS1 NLGN2 ENKUR NME7 RHOD CHL1 DCDC1 MOK ANKRD13D TEX9 INO80B DHX57 CASKIN1 DNAAF1	up	*
MIR8065	0.0059686	0.0487219	0.4070179	-0.2921958	-1.468118	118	RAB11FIP1 ABHD5 ST6GALNAC3 RASAL2 NR3C1 LYRM4 ZEB2 ARHGAP29 ZBTB4 PPP3CA EFCAB14 CYBRD1 PPT1 PTAFR CDK9 ATG7 PLEKHB2 LIN54 LACC1 RNF149 PIKFYVE SF3B1 LRCH1 SH2D4B CELF2 CACYBP BAZ2B MBNL1 ABL2 NBN ALDH2 FDFT1 FAM126B PDE8B	down	*
GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP	0.0025580	0.0258143	0.4317077	-0.2790806	-1.467901	164	LPIN2 ZC3H12C THSD1 CLDND1 FYN TGFBR3 ZEB2 SH2B3 ENTPD1 C1orf21 TNIP3 LUZP1 TTYH2 SLC7A11 STOM GATA3 ATP6V1B2 CD58 AHNAK COTL1 MIR24-2 LYAR KLRD1 PPP2R5C SH2D2A CRIM1 PI4K2A PHACTR2 IL2RB SEC14L1 GPR141 RHOJ GPR183 TBX21 CST7 TIGIT GPRIN3 RUNX3 EPHA3 TGFB1 ATXN1 GABARAPL1 SYT11 ARAP2 IL18RAP EPHA4 HAVCR2 TLR10 NABP1 IQGAP1 ARFGAP3 PIEZO1 CDC14A SH3BGRL3 DKK3 ITGB1 ZFYVE1	down	*
GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP	0.0038727	0.0354015	0.4317077	-0.2764731	-1.467754	174	HVCN1 GLIPR2 SPN GPR65 EGR2 CTSW MYD88 S1PR1 TGFBR2 RFTN1 LACTB ASAP1 GM2A NR4A1 PPP1R13B CRTAM PTGIR FOXO1 ST3GAL2 FMNL3 NFKB1 COTL1 SELL ID2 CCND2 PRF1 SMAD7 N4BP2L1 STK24 ARL6IP5 S1PR4 IL2RB INPP5B OASL CD48 NXPE3 CCR7 PTGER2 CD7 COL23A1 CST7 GPRIN3 KLF2 RUNX3 NKG7	down	*
GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_UP	0.0028586	0.0280520	0.4317077	-0.2825607	-1.467694	160	EPAS1 SLPI FCN1 ADTRP FABP4 LTA4H CYP27A1 LYVE1 BTNL9 THBD SEC22C GAS6 TRIB1 PDE2A ANXA1 MCTP1 LATS2 DACH1 NR4A1 EPM2AIP1 PDE4D TMEM38B MEFV MARVELD1 PTPRC ARHGAP9 DUSP1 CD300C DSTN BACE1 S1PR4 HCST HK3 OSM MAPK4 FOSB TFEB SERPINB1 ADPGK ANKRD12 ABI3BP IFNLR1	down	*
GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_UP	0.0036726	0.0340335	0.4317077	-0.2764483	-1.467476	178	CXCL3 DLC1 PECAM1 USP12 LRRFIP1 CDH5 TXNL1 CRY2 CHIT1 CIR1 WBP4 SLC11A1 IGSF6 PDE2A GM2A ZNF410 PPP2R2A TFEC TXN MTMR6 HNRNPA3 TNFSF12 TPP1 CD53 ARL4A PPP2R5A TP53BP2 ACTR2 NCOA1 METAP1 MUC3A MAGI2 SH3BP5 VPS26A SP3 PTGER2 UBB CD164 RUNX3 MSMO1 MYL12A NUP153 EHD1 PIK3C3 KCNA3 PPID GTF2B ARAP2 GPX3 PDLIM5 ALDH1B1 CALCOCO2	down	*
GSE17721_0.5H_VS_12H_CPG_BMDC_DN	0.0038727	0.0354015	0.4317077	-0.2763027	-1.466849	174	ACP5 DENND5A C18orf32 ENG HSD17B11 BAIAP2 SLC11A1 ANXA1 ADAM17 SERINC1 ZNF503 ZBTB21 PPP2R2A RBM4 SLC25A37 CLK1 ZEB1 IL10 STAT5A MEFV CASP1 SLC7A8 ZADH2 TJP1 LY96 PAPSS1 GCA SACM1L USP25 RPS6KA2 SYNPO2 GABARAPL2 INPP5B CPEB4 DNAJA1 ENPP4 GLIPR1 LYRM1 PRKCE CREB1 RHOQ PSMD12 CCR4 CHPT1 TCF4	down	*
GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP	0.0026196	0.0262215	0.4317077	-0.2767778	-1.466361	173	PRX OSBPL1A GLIPR2 CPEB2 EGR2 PLEKHF2 CTSW MYD88 GGA2 DNAJC3 LMNA SERINC1 IFI30 FAM122A RGCC GRN TFRC GMEB1 IL10 HAUS2 UBQLN1 CAPZA2 N4BP1 C6orf201 IL24 ANXA3 SIAH1 ZDHHC20 RAB6A RBPJ PHACTR2 AQP3 SKIL GRASP KRTCAP2 RUNX3 TIMP2 TSPAN14 RELL1 CCL20 GEM LDLRAD4 YAF2 CDC16 MGAT2 TMEM184B TMEM109 GLUL FAM126B PUM1 RABGEF1 ATP6V0A1 JDP2 FJX1 ATP11B	down	*
GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP	0.0043279	0.0384382	0.4070179	-0.2793466	-1.466135	165	SEMA3G SIK1 CRY2 PLEKHA1 INPP5A YPEL5 RPL23AP53 TMX4 TXNIP ANXA1 UBL3 STOM JAM3 RGCC MOAP1 DAB2 KLF7 ZBTB43 DUSP1 ARL4A TBC1D4 TBC1D5 SAR1A SGK1 JUN PLK3 THUMPD1 IDS PDZD2 GFPT2 CDK14 FOS SFTPC CBFA2T3 IRS2 ZNF136 FCGRT PHF11 TOB1 N4BP2L2 RLF IQSEC1 CEBPD CXCR4 USPL1 EPHA4 NLRP3 PTCH1 SLC2A9 OSER1 TIMP3 P2RX1 DAZAP2 NR3C2 C1orf115 PPP1CB SLC16A10 NR4A2 FPR1 TUBA1A CD69 DNAJB1 SETD2 FCHSD2 NKTR MATN1 SECISBP2 ARGLU1 ZNF331	down	*
GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN	0.0038727	0.0354015	0.4317077	-0.2761630	-1.466108	174	OSBPL11 EGR2 TMOD3 CD22 KIAA0355 DPEP2 RRAGC NAAA MTF1 ITSN2 RAB14 KPNA5 GMEB1 VASP DENND3 NFKB1 MAPRE2 RPL17 BTG1 TBC1D5 SERTAD2 VPS37A PHACTR2 SNAP23 ETV3 CELF1 JAK1 DHX15 MORC3 RPS6KA1 GAS6-AS1 ZNF350 KLF2 HIVEP2 HNRNPD DCK CBFA2T3 C16orf72 UTP3 ZNF267 SPOCK2 MBNL1 HACE1 CCR6 PUS10 TMOD2 UBE2D1 CCDC92 DOCK10 SKI CNOT8 DUT TGOLN2 MSANTD3 PLEKHA2 CTDSPL2 CD69 HMGN2 FXYD5 NMI ATP8A1 SKAP2	down	*
GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP	0.0056119	0.0465805	0.4070179	0.3248339	1.466051	166	MUC13 CEP72 BUB1B KIF18B DEPDC1 DEPDC1B CDCA2 RACGAP1 IQGAP3 LYPD6B NABP2 TPX2 RAD54B ALDOC MICALL2 TJP3 KIF23 EXOC4 EME1 KIF2C MPO ICA1 RHOBTB3 GPSM2 GAS8 CBY1 FADS2 KNSTRN PHF12 NEIL3 DENND1A G6PC3 JOSD2 TRADD TUBB2A USB1 AKAP8L ESCO2 ITFG2 NAT9 ARHGAP12 TADA3 CENPV ZCCHC17 ASCC1 FAHD1	up	*
GSE3920_IFNA_VS_IFNG_TREATED_FIBROBLAST_UP	0.0027402	0.0271193	0.4317077	-0.2816872	-1.465805	159	LPIN2 PTP4A2 PTPRE TTC7B FYN SNX32 GFOD1 DDX6 CRY2 YPEL5 CD22 ZEB2 ACOXL SEMA6D UBR3 CYP17A1 ENTPD1 CHRNE PPP3CA CTSD HPSE KLRD1 PEAK1 CRIM1 NCOA1 CREBRF VAMP3 NDNF RAPGEF1 PTGER4 FRYL PKD2 NKG7 PIK3AP1 GSAP DCAF5 PHLPP2 RXRA HACE1 ICAM1 ARAP2 IL18RAP	down	*
GO_POSITIVE_REGULATION_OF_TOOTH_MINERALIZATION	0.0059325	0.0485338	0.4070179	0.9705934	1.465746	2	TFAP2A ENAM	up	*
GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_FUSION_GFP_DN	0.0052579	0.0443562	0.4070179	-0.2862461	-1.465584	146	SLPI SOSTDC1 MS4A7 GLIPR2 SNX10 DPYSL2 CTSW MYD88 STX11 IGSF6 RBM7 MAN2B1 ENTPD1 C1orf21 ZDHHC2 PBX3 CAV2 NOSTRIN RIT1 CADM1 ATP6V0D2 PLEKHB2 GCA PINK1 C16orf54 GLB1 PHACTR2 CYB5R1 STAT4 RAB31 TBX21 GFPT2 SLC3A2 PKIA GSAP CD6 CD81 STX12 SYT11	down	*
GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP	0.0041186	0.0369897	0.4070179	-0.2834506	-1.465259	150	PEBP4 EGR2 ARIH2OS AQP9 ACSM1 RCHY1 IER2 CCNL1 GATA3 NR4A1 FAM122A CD93 ZEB1 BTG3 FBXO8 EIF1B PER3 ITPRIP ADO TRIM46 ID3 ZFAND5 STK17B KIF26A CCL4 JAM2 PER1 EVI2A SH2D2A MYH11 CA1 MAFF VAMP3 ARL5B ELP5 PLK3 JUNB GLIPR1 PTGER2 MALT1	down	*
GO_CYTOKINE_SECRETION	0.0031779	0.0304857	0.4317077	-0.2764101	-1.465123	181	FFAR4 NLRC4 IL17RB IL1A FCN1 IL1B LPL IL1RL1 GAS6 FGR CD36 ANXA1 MIR146A CARD16 FOXP1 GATA3 RGCC SPTBN1 CRTAM SRGN CD58 IL10 CASP1 CLECL1 CCL3 CADM1 TLR4 MIR24-2 CLEC9A RBPJ CD160 NOTCH1 CARD8 IFNGR1 PTGER4 CCR7 OSM CD34 MBP CHIA SERPINB1 LRRC32 ORM2 SYT11 RIPK2 NLRP3 HAVCR2 TLR10 MCOLN2 AIM2	down	*
GSE3982_DC_VS_NEUTROPHIL_DN	0.0020962	0.0222363	0.4317077	-0.2798236	-1.465116	166	SEMA6A LPIN2 SLC12A6 PDLIM2 LRRFIP1 SH2D3C RHOA NUMB IL18R1 ZEB1 MCL1 MYOZ3 MAP2K3 CFD SRSF5 MEFV STK17B STX3 DENND3 CXCL2 RECK ARAP3 PPP2R5A ANXA3 SNN S1PR4 NECAP1 RHOG JAK1 REL FSTL3 RALB ZNF350 CELF2 ATP6V0D1 ING3 FPR2 NAB1 NFYC ADAM10 PDE4B ETS2 SELPLG RLF CXCR4 TAB2 ARPC5 FOXJ2 PTEN TLK2 ZNF165	down	*
GSE3982_EOSINOPHIL_VS_TH2_UP	0.0027914	0.0275305	0.4317077	-0.2815399	-1.465039	159	PECAM1 CD55 PTPRE LRRFIP1 KL CD44 PLEKHF2 DDX6 MYD88 MEF2A BCL2A1 FUCA1 TRIB1 ANXA1 TM2D3 EIF1 RAB33B LITAF CAMTA1 NFE2L2 CLK1 MTHFR ARRB1 BIRC2 PTAFR ZFAND5 SMNDC1 RAB6A BTG1 TBC1D5 HCAR3 PSEN1 INPP5B ZNF835 HK3 PPM1F CALM1 TNFSF13 VAV3 GSAP AP1G1 KIAA0232 CES3 CYB5R4 BRWD1 KIT PTEN GRB10 CREG1 CNN2 C1orf115 RABGEF1 CHP1 C5AR2 CNR2 SVIL CLOCK	down	*
GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN	0.0053555	0.0450207	0.4070179	0.3245557	1.464914	167	KIF20A CENPF NDUFS6 TNFRSF11A NLE1 TOP2A NDUFS2 IFI44L AHCY PFKP MTG1 PPP5C DET1 DRC1 TNFRSF21 SEC61G TMEM51 NOP2 GNPAT C19orf47 TAPBPL LONP1 TRIO ZMAT5 MGMT PDRG1 PARP9 ANKRD31 USP18 STOML2 SIRT4 GBF1 CATSPER2 GMPPA STAMBP EIF3D C1orf109 MYEF2 CREB3L2 ETV6 HLCS TYSND1 AURKAIP1 PGAM1 SYNRG CENPE POLR1A FBXO34 ADARB2 RASGRP1 NELFA ACAD8 HEMK1 CHMP6 VPS26B WDR55 LCMT1 FOXRED2 TOMM40 EMB CCS IMP4 RCC2 AP1B1 HINT2 PLOD3 NCOA5 REEP4 RAVER1 HNRNPA1 PPM1G NDUFA9 GTF3A MRPS7 BCKDHA CWC15 IDH3A NDUFB10 DNAJC16 HTR7 VCAN CARM1 RPL24 GTF3C6 TBC1D13 PACS2	up	*
GO_POSITIVE_REGULATION_OF_CELL_CYCLE	0.0009871	0.0125831	0.4550599	0.3067619	1.464845	308	HMGA2 DDX11 CDC45 CHEK2 CCNB1 PAGR1 STOX1 NDC80 BRCA1 CDK4 SMPD3 RACGAP1 E2F8 GTSE1 DBF4B KIF14 AURKB ECT2 ESPL1 CDC6 TFDP2 PRKCA CDC25A DTL CDT1 RANBP1 CASP2 SMARCD3 KIF23 FOXA1 RHNO1 KIF3B LGMN MSX2 MAP10 GPER1 AURKA TPR MSX1 POC1A CXCR5 CDCA5 GPSM2 CDC25C SOX4 TGM1 EGFR CHEK1 MAD2L1 MDM2 PML CNOT3 MNAT1 STXBP4 PSRC1 CKS1B NUSAP1 ANAPC5 CDK1 CENPJ E2F1 FEN1 EZH2 CNOT11 SPAG5 EGF RAB11FIP4 MTBP GIPC1 CCNE1 DLGAP5 CNOT2 MTA3 MYBBP1A PKP4 NUDT16 KIF20B TRIM32 ASNS ATAD5 CDC7 ANKRD31 PROX1 SH2B1 CENPV	up	*
MIR4713_5P	0.0048424	0.0417203	0.4070179	-0.2903002	-1.464788	126	EREG NOVA2 INPP5A DYRK1A CYP4A11 TRIB1 EDEM1 ZBTB4 CD36 C1orf21 EIF5 ZEB1 ATP6V1H CYP4X1 ZSWIM6 ITGAX IRAK2 SHC4 LBH ADIPOR2 SNAP23 ZFP91 OSBPL9 PIK3R1 PSTPIP2 HOMER1 DENND4A PIK3AP1 ZNF596 CNOT7 MYOCD ANKRD12 TDRP IPO5 MEGF9 PALD1 CYTH1 SYNPO2L LDLR SPOPL	down	*
YAMAZAKI_TCEB3_TARGETS_UP	0.0018597	0.0202252	0.4550599	-0.2840574	-1.464380	149	EPAS1 SEMA6A GREM2 RAMP2 THBD CDH5 RCOR1 PDE1B SOX17 BACH1 CITED2 SUSD2 HSPG2 SEMA6D PTPRM CYB561A3 NR4A1 SRGN TCF7L2 CST3 SNAI1 CASKIN2 PARVB ERP44 DOCK9 ID2 CCND2 LMBRD1 PTH1R FAM189A2 CTSZ MBNL2 COBLL1 RNF24 YPEL2 CALM1 GATA6 JUND YAF2 TFPI FDX1 GLUL KIT TIMP3 HSDL1 HERPUD1 KALRN GHR ITGB1 ZYX ATP1B1 SYCP3	down	*
GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN	0.0031106	0.0299409	0.4317077	-0.2793573	-1.463487	157	SLC12A6 DENND5A CD55 CD44 TXNL1 SOX17 TBC1D7 ARL8B TRIB1 LYRM4 TRA2B ITGA5 MS4A14 NFE2L2 TCF7L2 CASP5 MYO1B SPAG9 RIT1 CDKN1A ITGAX CCDC59 RSL24D1 TP53BP2 ETF1 CREM HRH1 RAPGEF1 FSD1L ATP13A3 SUCNR1 DENND4A CDK17 SLC22A1 RUNX3 EHD1 TSPYL6 SERPINB1 TSC22D1 CTNNAL1 IFNAR1 PIM1 HSPA2 CYTH1 SAMSN1 IAH1 SLC16A10 UBAP1 SPSB1 MB21D2 HES4 SH3GLB1 PNLDC1 FPR1 EYA3 MT1E LAMP3 GPR137B TRIM13 BBIP1 PLA2G5 DERL2 HIVEP1 SYDE2	down	*
GO_REGULATION_OF_LEUKOCYTE_DIFFERENTIATION	0.0006702	0.0093431	0.4772708	-0.2673862	-1.463392	230	CD101 TAL1 GATA2 DCSTAMP GAS6 TGFBR2 TRIB1 LILRB3 IL23A RHOA ANXA1 FBXO7 ADA KLF10 FOXP1 HLX GATA3 RB1 TRAF6 SFRP1 ZEB1 ZMIZ1 EVI2B NRARP SLC46A2 SOCS5 CCL3 PTPRC AXL ID2 TLR4 SMAD7 INHBA IL7R UBASH3B CYP26B1 MIR17HG NCKAP1L CD80 JUN MITF CUL4A TYROBP PIK3R1 CD83 CREB1 MALT1 SIGLEC15 RC3H1 AP3B1 FSTL3 TBX21 RASSF2 ZNF683 FOS RUNX3 CD74 CR1 TGFB1 ZBTB1	down	**
SMTTTTGT_UNKNOWN	0.0003721	0.0058397	0.4984931	-0.2563284	-1.463244	306	DAB1 ZNF366 GATA2 RCOR1 SLC10A1 DDX6 CITED2 QKI BMPR2 KCNN3 ANAPC15 WBP4 ERG NFIX TRA2B TTL ZNF503 FOXP1 LCP1 SRSF2 LHX6 LRRN4CL CLK1 PDE4D GPM6A GLDN SRSF5 RUNX1T1 USP2 KLF7 SYCP2L ITPK1 CADM1 GPR85 KIRREL3 ID2 USP44 CXXC4 CLK4 DSTN GNAQ ZNF706 VCPKMT PIAS1 FOXN3 SPIN1 WNT9A RYBP SRSF3 CPEB4 DDX17 EPC1 CCR7 SP3 PABPC4 DDX5 STX5 TPP2 OGFRL1 GFPT2 FGFR4 SLC3A2 GPRIN3 PTP4A1 EHD1 TCF4 TGIF1 YTHDF2 ZBTB11 C16orf72 LTBP1 ETS2 MBNL1 ELF5 ARPC2 ZNF143 CTTNBP2NL LMOD1 EPN2 TIAM1 PP2D1 CXCR4 USPL1 TAB2 HNRNPC SIN3A MTUS1 KIF1B NRG1 SFPQ TLK1 SLFN11 EIF4G2 ARHGEF17 DUSP6 NR4A2 FUS SLC38A2 YRDC PTGS1 EBF1 DPF3 MAP4K2 MTSS1	down	**
GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN	0.0035481	0.0332526	0.4317077	-0.2764180	-1.462950	169	ACP5 ST8SIA6 FABP4 ADCY9 LYL1 CALCRL BMPR2 S1PR1 TSHZ1 GGA2 PDE2A ZBTB4 PCYOX1 TMEM74B RB1 EVI2B KIF1C TLE4 CCDC82 RIT1 NCOA1 NINJ1 TBC1D5 AXDND1 CCNY ASNSD1 JUNB EPC1 JAK1 GPR183 RASSF2 CDK14 ATP6V0D1 ICAM2 NAA16 TTBK2 MCUR1 RELL1 MFNG CCR6 IER5 IQSEC1 TEX10 SIK3 FOXJ2 AIM2 RHOT1 MAN1C1 FNBP1 SETX CHIC2 LNPEP HEY1 FPR3 FXYD5 GPR137B FCRLA TES WDR26 RC3H2	down	*
GSE3982_MAST_CELL_VS_NEUTROPHIL_DN	0.0028426	0.0279281	0.4317077	-0.2811343	-1.462928	159	SLC31A2 SEMA6A SLC12A6 DENND5A MIR22HG LRRFIP1 LINC00472 SH2D3C CDC42EP2 C5AR1 SLC15A3 NEDD9 SLC11A1 ASAP1 SERINC1 ADIPOR1 ZEB1 SPI1 HERC3 PTAFR UHRF1BP1L VASP ARNTL NPR3 SPAG9 ARAP3 EVI2A GNAQ MARK3 PRCP S1PR4 AQP3 TYROBP JUNB ZNF407 IP6K1 ACSL1 MBP AOX1 PIM1 KCNA3 PPIG KAT2B SELPLG RLF XKR8 MARC1 KCNK7 JMJD1C ZNF165 DAZAP2	down	*
GO_REGULATION_OF_LIPID_METABOLIC_PROCESS	0.0001922	0.0033271	0.5188481	-0.2552984	-1.462592	323	SC5D ABHD5 TEK PPARG IL1B WNT4 BMP2 SIK1 INSIG1 HCAR2 CAV1 IDI1 HMGCR ALAS1 CDC42 MIR27B CYP4A11 FGR APOD CD36 ANXA1 STARD4 LACTB ASAH1 ABCG1 ADIPOR1 ABHD6 RB1 APOC1 PDGFA FABP5 SNAI1 SORBS1 ACSL3 KLF4 REST SOCS2 SOCS5 NFKB1 PDE3B NR1D2 ID2 ZMPSTE24 CPT1A ADIPOR2 PPP2R5A PIK3R5 NRBF2 NCOA1 PDK4 FLT1 NSMAF DDX20 HSD17B13 SOCS3 DHH CCDC3 MTMR9 CCR7 GLIPR1 PIK3R1 PRKCE CREB1 PANK2 FGFR4 ACSL1 PNPLA2 TREX1 CD74 TGFB1 VAV3 FPR2 MTMR2 IRS2 NFYC CD81 CPT2 ACADL TSPO RXRA RBL2 FGF2 SF1 ORMDL1 ACACB CREBBP CD19 SREBF2 SIN3A ACADM KIT FDFT1 RORA LDLR	down	**
GO_REGULATION_OF_CYTOSOLIC_CALCIUM_ION_CONCENTRATION	0.0004460	0.0067145	0.4984931	-0.2626401	-1.462132	283	HCRTR1 GPR17 RAMP3 CD52 SWAP70 MCOLN1 EDNRB CD55 GATA2 F2RL3 P2RY1 GPR65 TRPC3 FYN JPH4 CCRL2 CAV1 ADRA1D GTF2I ADCYAP1R1 TBXA2R C5AR1 S1PR1 CD36 JPH2 ATP2B1 KCNK3 MS4A1 PDE4D TMEM38B GPR4 SYNPO PTGIR CCL3 PTPRC PTGER3 HTT GPR157 UBASH3B CALM2 PLCD1 PTH1R KCNA5 S1PR4 SLC8A1 PDE6A PDE6B ADRA1A JPH1 GSTO1 PTGER4 CCR7 ACKR3 PRKCE PTGER2 GRIA1 PRKACA CLN3 PLCG2 CALM1 PKD2 CCR4 FPR2 SLC8A3 CCR1 NPTN GNA13 GPR18 CALB1 CCR6 FGF2 ABL2 FKBP1A CXCR4 CCR9 BOK CD19 EDN1 MCOLN2 P2RX1	down	**
KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN	0.0039330	0.0358124	0.4070179	-0.2739525	-1.461150	183	HSD17B11 WDR74 NEDD4L AQP9 SRSF7 VAMP2 PLEKHA1 LAMP1 IER2 EIF1 NLK ABCG1 FOXP1 KLF6 PRSS12 GATA3 RGCC ADRB2 ZYG11B RHOB ARRB1 KLF4 NR1D2 SELL PNRC1 CCND2 PER1 DUSP1 SMAD7 IL7R RBM39 CTSS SOCS3 JUN NOTCH1 KCTD12 GSTO1 CCR7 DDX5 CD7 RALB SLC3A2 FOS FOSB NR2C1 SBF2 PIM1 RGS2 JUND SESN1 SETD4 TDRP TRAF1 TMX2 RNF38 SKI MCOLN2	down	*
GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN	0.0028028	0.0276218	0.4317077	-0.2757771	-1.461059	173	NLRC4 KMO SLC12A6 SOWAHC CCRL2 FLVCR2 TMEM138 HPS5 ADAM17 HSPB1 NLK ZNF410 ZNF697 MOB3C IL18R1 NFE2L2 LAMTOR3 CES1 ARHGEF2 BTG3 TUBB6 ATP6V1B2 LCMT2 ACSL3 DAB2 VASP SPAG9 SLC25A3 PSEN1 TRIM55 CRNKL1 SERPINB8 DNAJA1 GAS2L3 SLC3A2 SIGLEC17P MSMO1 BTBD7 SAV1 KYNU ZNF267 PITPNA SLC43A2 WDR1 HSP90AA1 LRP12 HSPA8 LINC00884 TNFRSF10D MED31 GPN2 ATP6V0A1 C1QB FUS ZFYVE1 SLC26A11 YRDC CYP51A1	down	*
TGCACTG_MIR148A_MIR152_MIR148B	0.0006895	0.0095243	0.4772708	-0.2621471	-1.461039	268	PNPLA6 OSBPL11 SIK1 DDX6 QKI AKAP7 GPCPD1 ZCCHC2 S1PR1 ARL8B ELMO1 OTUD4 MOB1B TXNIP BMP1 PTPRM BEST1 HECW2 MTF1 ITGA5 PICALM NLK SLC7A11 ITSN2 GPM6A AGO4 NRARP KLF4 STX3 ITPK1 MGAT4A EPS15 CUL5 PRICKLE2 NCOA1 MMP19 SNN PDK4 TMEM9B SLC25A3 ADCY2 PHACTR2 MTMR14 MITF CPEB4 CNTN4 FBXO11 KLHL18 TRAK2 ITGA11 DEDD NDST1 AGFG1 FOSB PHF3 KIAA0232 RSBN1L SKIDA1 ATXN1 NPTN LTBP1 PLAA ARPP19 RXRA DOCK6 ELF5 MIER1 INO80 EPN2 CYB5R4 UBE2D1 RNF38 MMD LDLR FAM13B NAA15 ZFPM2 USP48 PPP1CB ZFYVE26 STARD13 CDC14A ARHGEF17 CFL2 CLOCK NOG EFNB2 YWHAB SRSF11 C6orf62 UBE2W SCAF11 ARHGEF12 EP300	down	**
GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS	0.0040681	0.0366383	0.4070179	0.3198357	1.461012	185	PKHD1 SPICE1 MDM1 NEK2 BRCA1 STIL CEP70 PLK1 TPX2 EFNA5 CCNF CIB1 RANBP1 CEP250 ARMC4 BICD1 MAP10 AURKA TPR POC1A FSD1 KIF11 GPSM2 CHEK1 CLIP3 DNAH11 TRPV4 CCDC40 PSRC1 DRC1 PAK1 CEP97 CENPJ SPAG5 PRKAA2 SPEF1 TACC3 TRIM37 MAP6D1 TRAF3IP1 CHMP4C CDK5RAP2 CKAP2 STMN3 KATNB1 TTLL6 NEFH NUP62 CEP85 CATSPER1 ALMS1 APC2 CHMP1A MARK4 CHMP2A ERBB2 CAMSAP3 MAP9 CLASP1 RANGRF DNAAF1 DRG1 DYNC1H1 KLHL42 PLK4 GSK3A AKAP9	up	*
GSE3039_ALPHAALPHA_VS_ALPHABETA_CD8_TCELL_DN	0.0027292	0.0270318	0.4317077	-0.2774058	-1.460681	170	FCN1 SPN CTSW BACH1 MARCO GIMAP6 HEG1 CD5 CHMP1B GNGT2 FOXP1 ADRB1 SLC25A37 APOC1 PTGIR PPM1K PLEKHM3 ROCK1 NFKB1 PTPRC PTGER3 PRICKLE2 CA1 CD300LB HCK SLC25A33 ARHGAP17 CYB5R1 NXPE3 RAPGEF1 UBAC2 CREB1 CD7 TBX21 MBP ICAM2 PPTC7 NKG7 VPREB3 GPR18 ATAD2B CALHM2 SPIB PIP4K2A CD3G PDE8B P2RX1 CREG1 GIMAP4 FCRL1 PSIP1 EBF1 OTUB2 CD79B DNAJC8 VSTM4 S1PR5 STX16 OMA1 RAB39A ABCA3 TNFRSF13C IRF4 NIPAL3 PPP1R14A CD4 MEPCE KLRC1 SLC18A2 PLXNC1 FLT3 RASGRP3 DPP4	down	*
KATSANOU_ELAVL1_TARGETS_UP	0.0050995	0.0435256	0.4070179	-0.2894061	-1.460276	126	CD52 FOXF1 SLC16A4 ENG EMCN LDB2 SUSD2 TXNIP KLHL30 SLC7A7 SLC25A17 STOM TNNC1 MPEG1 NES LAPTM5 KCNMB1 IGFBP2 MYH11 CTSS ESD TMTC1 C1QA PDE5A PCGF5 LPCAT2 FAM177A1 PALMD SORT1 CCDC68 GPX3 ITPRIPL2 EPHA4 DAPK1 SPSB1 C1QB FJX1 CTSH DUSP6 PLEKHA2 SYCP3 IER3IP1	down	*
GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP	0.0035362	0.0331538	0.4317077	-0.2747643	-1.459523	179	EPAS1 NLRC4 SLC12A6 PECAM1 HHEX LYL1 CCDC88A CD9 TGFBR2 NFATC3 TMX4 ZBTB4 FBXO7 PCYOX1 ECHDC1 IFI30 GRN EPB41L2 RHOB ZCCHC24 GAA TPP1 KLF7 ATP6V0D2 TLR4 CD302 FRMD4A ARHGDIB NCKAP1L DDHD1 RNF141 SEC14L1 KCTD12 GLUD1 SNX2 GMFG CLN3 ATP6V0D1 KLF2 ALDH3B1 TIMP2 DOK2 FCGRT STK40 BMP2K ESYT1 SLC2A9 CCDC92 B3GNT2 SLC35A1 CBX7 ATP6V0A1 PHYH CRTAP	down	*
GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	0.0019533	0.0210552	0.4317077	-0.2830843	-1.459363	149	SIDT2 FAM167A SIK1 INSIG1 OTUD1 PRKAR1A SWT1 MAP3K8 RNF125 KLF6 CD93 KLF4 FAM76A KLF11 SPAG9 UBQLN1 NR1D2 PRF1 SH2D2A DEGS1 RASGEF1B RYBP OASL PLK3 REL TCP1 TNFRSF9 DENND4A SLC3A2 FOS ATP6V0D1 CCR4 TGIF1 KCTD10 CTNNAL1 LRRC32 TAGAP CRY1 MAGOH NT5C2 ZBTB25 BOK OSER1	down	*
GSE19198_6H_VS_24H_IL21_TREATED_TCELL_UP	0.0038589	0.0353253	0.4317077	-0.2756734	-1.459009	169	OLR1 TMEM52B FGD5 C18orf32 EGR2 SH2D3C LINC00622 NCF2 GALNT18 LRRFIP2 KCNAB1 SLC44A2 HBEGF DNAJC5B GM2A SLC7A11 ZFYVE16 BTG3 TUBB6 ITPRIP PPT1 ADO PLAUR PRKD3 PLBD1 ATF3 ATP6V0D2 ARAP3 PLEK HTRA4 PLCD1 PKIG ARL6IP5 SLC8A1 HCAR3 BCAR3 CCR7 CD83 LGALS2 CDK14 SIGLEC17P RHOQ	down	*
LET_7C_3P	0.0000203	0.0005083	0.5756103	-0.2460435	-1.458950	508	CXCL3 FOXF1 TAL1 USP12 CD55 KCNA2 CPEB2 PRKG2 RDX RAPGEF2 THBD PTPRB BMP2 TMEM170B OTUD1 MED4 NEDD4L CITED2 HMGCR NR3C1 DSCAML1 GNPTAB TSHZ1 MOB1B ZEB2 SH2B3 TRA2B UBL3 MCTP1 HECW2 MAP3K8 RANBP9 NLK SLC7A11 DACH1 SLAIN2 FOXJ3 PPP3CA SPRY2 HNRNPU TCF7L2 GPM6A ATP6V1B2 FLI1 ZMIZ1 HMGN1 STAT5A FOXO1 KCNMA1 PPP6R3 DENND6A KLF4 COQ10B RRM2B KLF9 DAB2 ZFAND5 FBXL3 KIF26A FAM49B FMNL3 DOCK9 NPAS3 UBE2E2 PTPRC ARHGEF26 M6PR PTGER3 CLK4 RNF139 PPP2R5C SLC6A6 RSL24D1 FAM76B AKIRIN1 TANC1 SERTAD2 CREBRF PPP2CA RGPD3 PHTF2 KIF13A EBF2 SF3B1 MITF LRCH1 SHOC2 ELOVL7 FERMT2 SKIL SP3 FBXL16 MBNL2 PCGF5 HERC1 PRKCE ATP13A3 SLC10A7 MORF4L1 YPEL2 NECAB1 HIVEP2 NAA16 BTBD7 TSPYL6 SRSF4 TSC22D1 GNAI1 KHDRBS1 MAP3K2 PPP3R1 GNB4 ANKRD12 NPTN GNA13 RIMKLB PHF2 ADAM10 MBNL1 ATAD2B RXRA CEP170 SEC63 CXCR4 CDKN1C LRP12 CYB5R4 ZDHHC21 GRIN3A ISCU KPNA4 MBD5 PALD1 CUL3 SIN3A NFKBIA JMJD1C PDE4A NALCN GPR171 RORA COL13A1 DOCK4 GRB10 TLK1 WDFY3 PUM1 BMI1 MIER3 DNAJA2 ZBTB44 HAT1 PIM3	down	***
GTGCCAT_MIR183	0.0047477	0.0410428	0.4070179	-0.2834578	-1.458933	151	GREM2 TTC7B QKI CTDSP1 YPEL5 NR3C1 USP47 SEMA6D KIAA0355 HBEGF BZW1 FOXP1 PPP2R2A SRSF2 MAPK8IP1 PDE4D MTMR6 TLE4 FOXO1 ERP44 TMSB4XP8 PPP2R5C FAM76B BTG1 PPP2CA VPS37A PLEKHA3 RAB8B FOXN2 SNX1 UNC13B CELF2 DAGLA ING3 PPP2CB C16orf72 PIM1 GNG5 MBNL1 ARPP19 AMD1 BNIP3L RNF138 EPHA4 MAP3K4 SIN3A ZFPM2 SPOPL SLC35A1 ZFYVE26 ARHGEF18 EGR1 PLAG1 CFL2 ITGB1 CSNK1G3 SRSF11 PTDSS1	down	*
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN	0.0001924	0.0033279	0.5188481	-0.2549054	-1.458798	327	AKAP5 MS4A7 PHACTR1 CD55 PDE1B STXBP6 SOX17 GFOD1 LDB2 LONRF1 RXFP1 NEDD9 TGFBR2 FAM49A KCNAB1 ATP2B1 NFIX STARD9 LMNA REV3L KLF10 FOXP1 ANPEP PEX5L FOXJ3 ZEB1 SOX7 ZSWIM6 ST3GAL2 RUNX1T1 CDIP1 PRKD3 DAB2 THBS1 KLF7 C1QTNF7 PER2 C9orf72 PAPSS1 PTGER3 CD300C INHBA PTCHD4 MATN2 ADAMTS8 UBASH3B NRROS SERTAD2 TSPAN18 RBPJ ID4 CHDH RYBP SYNPO2 PKNOX1 SLCO2B1 CABLES1 C1QA SH3BP5 RHOBTB2 SLC14A1 BMP3 BTD TYROBP CSTA RHOJ CD83 GYPC MFAP4 RTN4R ENTPD4 GRIA1 RASSF2 GAS2L3 CTTNBP2 HIVEP2 PKD2 ZNF521 TCF4 FEM1B SKIDA1 TGFB1I1 MCUR1 C8orf37 MEIS1 MRGPRF JUND BMP2K SPARCL1 PAMR1 PARM1 CDC42EP3 DIXDC1 GRIN3A RBMS3 BCAT1 PTEN DUSP7	down	**
ELF1_Q6	0.0015745	0.0179019	0.4550599	-0.2679539	-1.458782	208	FFAR4 TEK SCIMP RASIP1 KLF13 TIE1 CLEC12A CDH5 MYADM CALCRL ELMO1 KCNAB1 BRINP3 CHMP1B GNGT2 TNIP3 PPP3CA CD37 LIMS1 PSPN VIM TLR4 TM6SF1 FCER1G ALOX5AP ELMSAN1 IL7R PRDM5 CNOT6L PI4K2A ARHGDIB RPL17 MTPN NCKAP1L MYO1C ARL6IP5 S1PR4 C1QA MITF TYROBP SNX2 IRF8 GRB2 STX5 REL TNFSF13 TGFB1 MR1 ARPC2 SF1 ELOVL1 ARRB2 CREBBP OSER1 VSIG10 ABI3 SAMSN1 IQGAP1 PUM1 DNAJA2 FCRL1	down	*
GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP	0.0045050	0.0396261	0.4070179	-0.2746810	-1.458239	174	SLPI SOX18 CXCL16 LHCGR THBD FOLR1 SUSD2 PAFAH1B2 TBXA2R PEAR1 ABCB1 EDEM1 MTF1 ABCG1 GRN SRGN BTG3 IL10 CASP1 ROCK1 CEBPA SCAF4 CDS2 AXL TLR4 ANXA3 MYO1C KIF13A HUNK CD83 N4BP3 PTGER2 CST7 SNX9 RBKS EHD2 PPTC7 TIMP2 JMJD6 FEM1B CD81 PLEKHO2 HAUS3 LDLRAD4 RIPK2 ITGAE TRAF1 TNFSF9 MMD SPSB1 ENDOD1 SLC38A2 HEY1 DNAJB1 SCAF11 ESCO1 ARHGEF12 FANCC NFIL3	down	*
GSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN	0.0017636	0.0194193	0.4550599	-0.2763747	-1.458205	171	SASH1 LMO2 BACH1 AQP9 FAM49A LILRB3 IL23A TNFRSF8 ADA SLC7A7 C1orf21 TNIP3 KLF6 PTX3 HLX SLC25A37 CD93 TFRC CASP5 IL10 SAP30BP ATL3 P2RY2 CXCL2 IL7R HES1 TP53BP2 IL24 KANK1 HCAR3 FLT1 IL6 SOCS3 CD48 ETV3 STAT4 MAP4K4 WTAP ENPP4 PNPLA8 SIGLEC15 SERPINB6 FSD1L GTDC1 GFPT2 SLC22A1 CALM1 RIN2 PIK3AP1 SERPINB1 FPR2 PIM1 ANKLE2 TNFAIP8 MIR155HG IER5 RND1 PLGRKT PTEN SAMSN1 TRIM36 PAPSS2 CSF2 SLC16A10	down	*
GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN	0.0019049	0.0206125	0.4550599	-0.2755174	-1.458126	172	EREG RAMP3 IL1A GLIPR2 CPEB2 CD44 HMGCR SLC15A3 VAPA IL1RN TRIB1 APOD PTPRM HBEGF MAP3K8 LITAF HDC KLF6 SLC7A11 SRGN TUBB6 PTPN12 IL10 STAT5A ZFAND5 CLIC4 CDKN1A SELP ID2 CCL4 MAFF MEDAG TDRD7 HCK SLC25A25 EBAG9 ST6GALNAC4 ELP5 FERMT2 TNFRSF9 CD164 RUNX3 EPPK1 TREX1 RIN2 EHD1 FPR2 TBRG1 SOD2	down	*
GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP	0.0027984	0.0275889	0.4317077	-0.2739293	-1.457892	177	KMO ARHGAP31 IL1A ZC3H12C IL1B TRPC3 CCRL2 ADAM17 ITGA5 MOB3C NFE2L2 LAMTOR3 ATP6V1H TUBB6 ATP6V1B2 PTPN12 STX3 MYO1B SPAG9 DPH3 CDKN1A ACTR3 PLEKHB2 ADIPOR2 PAFAH1B1 PIK3R5 CRIM1 SERPINB8 PSMA1 DNAJA1 GSTO1 NDUFV2 SNX9 HIVEP2 MSMO1 SAV1 TSC22D1 DUSP5 PIM1 KYNU ZNF267 TNFAIP8 TEX10 HSP90AA1 HSPA8 KLLN CREG1 LINC00884 RNF13 ARFGAP3 TNFRSF10D MED31 GPN2 CTSH KCNE1 OSGIN2 SH3GLB1 ZFYVE1 EYA3	down	*
GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN	0.0052042	0.0440962	0.4070179	-0.2745195	-1.457104	180	EREG ACP5 OLR1 HHEX LTA4H THBD ENG LYL1 FYN LPL ST3GAL6 BAIAP2 SLC11A1 TGFBR2 GGA2 ADA SLC7A7 LMNA LAIR1 TMEM41B ARHGEF2 SETD3 AHNAK FOXO1 HNRNPA3 ZCCHC24 CDK9 PDE3B DNTTIP2 PPP2R5C SERTAD2 KANK1 PDHX BCAR3 GAS2L1 DNASE2 GSTO1 GRB2	down	*
MCCABE_BOUND_BY_HOXC6	0.0023199	0.0239832	0.4317077	0.3052043	1.456940	307	KIF12 LEMD1 MEGF10 CHST6 ZNF84 PPIP5K1 NOXRED1 PGM2L1 CREB3L4 ZFHX2 E2F8 KIF14 NPIPB3 PMS2P5 ALDH18A1 DIO2 GLB1L3 ARHGAP33 COCH TMEM132D LIG3 ASXL3 AK8 CLPTM1L BTRC C19orf48 ZFYVE27 TIGD4 BPIFB1 THBS4 C20orf96 CXCR5 MAP1LC3C WDHD1 HOXC6 SGPL1 SERPINA3 BLOC1S1 ZNF785 AP1M2 CGB7 ORC6 RAD51AP1 PTGDR2 EDN2 RBAK FRMD5 FRMPD2 CBX5 PAK1 STON2 BCAS4 PICK1 PKD1P1 ZNF541 SNAPC1 DNAH5 FER1L4 CBFA2T2 WDR86 SUSD4 RP9 SPEF1 CCDC151 DHODH MRPL52 RBM12B ZNF239 GAS2 GUSBP1 DNMBP TMEM30B SLC1A3 ZCCHC17 CHTF8 PIGU CD2BP2 VCAM1 PTHLH SKAP1 LRRK1 TTLL6 CDH11 GADD45G KRTAP5-9 DBNL SHCBP1 TUBGCP4 TNKS1BP1 FARSB ZSCAN29 RHOD SCN9A SBNO2 SLC36A1 ERRFI1 NUP210 DPP10 SLC39A1 CCDC91	up	*
GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN	0.0023341	0.0240767	0.4317077	-0.2739635	-1.456658	175	USP12 NUP54 FOSL1 TMEM138 STX11 OTUD4 IL23A CLCF1 TRA2B LMNA PPP1R15B BTG2 MAP3K8 CAMTA1 SERPINB9 PPP2R2A RBM4 RGCC NDEL1 ARHGEF2 TFRC SDCBP TAF9 MIR17HG CRIM1 ETF1 RYBP PLEKHA3 RAB8B ARL5B DNLZ RHOG PABPC4 CD83 KBTBD8 TCP1 CEBPZ SLC3A2 FOS RRN3 PSMD12 PPTC7 NIPA2 SLIRP ADPGK KANSL2 ZNF267 PHLPP2 AMD1 ICAM1 ITPRIPL2 TRAF1 KPNA4 TMX2 MAFK	down	*
GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN	0.0019827	0.0212919	0.4317077	-0.2751462	-1.456162	172	SOSTDC1 CD101 DLC1 LTA4H SLC16A4 INSIG1 LY86 FCER1A MYD88 BMPR2 SLC39A8 S1PR1 BCL2A1 NFATC3 CD8A IER2 ANXA1 HSPE1 HBEGF EIF4E ATP6V1H CD58 SELL IGFBP2 XCL2 SMAD7 MATK GNAQ TP53BP2 CALM2 RBM39 HESX1 WASF2 JUN TMPRSS11D RPL9 GPR183 PTGER2 ACSL1 UBB PTP4A1	down	*
MIR548P	0.0000166	0.0004304	0.5756103	-0.2448079	-1.456011	504	EREG COL25A1 SWAP70 SGK3 TDRD6 SECISBP2L OSBPL1A GATA2 ZC3H12C CPEB2 BMPER STXBP6 LONRF1 CORO1C THAP2 QKI PRKAR1A KCNN3 CD9 SLCO2A1 OTUD4 LAMP1 ACER3 ZEB2 SH2B3 SPG21 B3GNT5 SLC36A4 SLC7A7 LATS2 PKD2L2 MTF1 REV3L ZBTB21 FOXP1 HIPK3 KLF6 EIF4E PPP3CA JAM3 RB1 PDE4D KDSR AGO4 TBC1D9 SCP2 LIN7C YBX3 HAUS2 THBS1 CEBPA SOCS2 RBMS1 ARHGEF26 CD302 PNRC1 CCND2 ZBTB43 MBD2 PEAK1 KIAA0408 CYP26B1 EFR3A SERTAD2 GPBP1 CREBRF FMNL2 SYNPO2 KIF13A RNF141 RAB8B SLC35E4 ARL5B ARL6IP6 RAB31 DESI2 CNTN4 HSPA1B FOXN2 VPS26A WTAP SKIL MPZL3 PIK3R1 PCGF5 THUMPD1 RC3H1 FSD1L AP3B1 CXCL5 ZNF597 RNF24 OGFRL1 YWHAZ PXK ZNF407 CELF2 AGFG1 RHOQ CTTNBP2 SRSF6 MAPK8 TSHZ3 NAP1L5 VAV3 TMX3 PHF3 SRSF4 METTL14 CCP110 IRS2 CSDE1 TOB1 THAP11 MACF1 PGGT1B ADAM10 KTI12 ATAD2B INO80D HACE1 HELZ JUND MIER1 ABL2 ZNF143 CTTNBP2NL ITPRIPL2 VGF SFT2D1 TIAM1 FBXO30 TOB2 ZDHHC21 SOAT1 KPNA4 ING2 STK4 TTC28 TIMP3 SCAI FNIP2 SNAP29 PRKG1 FGFR1 RORA C2orf42 DUT WDFY3 SPOPL MIS18BP1 EVI5 MAN1C1 ZBTB44 SCLT1 AFTPH SLC16A10	down	***
MIR340_5P	0.0000035	0.0001138	0.6272567	-0.2353208	-1.455606	660	SIRPB1 EPAS1 GPR15 DLC1 EDNRB GREB1 SECISBP2L HHEX PTPRE RAB3C RUNDC3B ZBTB34 CAV1 QKI MTMR10 C3orf70 GALNT18 TET2 OTUD4 NFATC3 RHOA CD36 RBM7 UBR3 ATP2B1 LACTB UBL3 SLC36A4 HECW2 ENTPD1 RAP1A ZNF503 REV3L SPIRE1 ZBTB21 PTX3 SLC7A11 JAM3 NFE2L2 TNS1 ZFYVE16 PDE4D HERC3 FBXO8 EVI2B CWC22 PRDM16 NRARP NPNT CASP1 ZSWIM6 TCP11L2 TACR2 PLAUR RUNX1T1 REST RRM2B STK17B MYO1B FBXL3 CLIC4 MYRIP SPAG9 SSH1 ERP44 MGAT4A RBMS1 NR1D2 CTBS ACTR3 PIK3C2A ADIPOR2 TBX5 SLC25A32 CLIP4 CYP26B1 FAM76B NCKAP5 LIN7A ANO2 LIN54 TOPORS SACM1L MTPN USP25 SNX3 MCMBP MYLIP CREBRF PRKRA PRDM11 PDIK1L VPS37A CREM PKNOX1 PHTF2 MED28 PNO1 NEK7 APPL1 PLEKHA3 PDCD6IP UTRN NDNF SF3B1 TMTC1 GABPA JPH1 MSRB3 OSTM1 HELQ FOXN2 IPO7 SKIL DDX5 IDS CREB1 LUZP2 COBLL1 FSD1L ATP13A3 TPP2 THSD7B OGFRL1 BLOC1S6 SLC25A24 CTTNBP2 PELI1 CALM1 PTP4A1 YTHDF3 MYL12A TSHZ3 EPHA3 VAV3 TMX3 ITGA9 NR2C1 ABHD13 ZBTB11 GNAI1 EWSR1 MAP3K2 ATP6V0C CCDC68 HNRNPH3 ADPGK ANKRD12 MAGOH GNA13 MACF1 SPOCK2 POLK PDE4B SMAD2 INO80D LDLRAD4 FGF2 YAF2 SCN7A EPN2 SEC63 ACAP2 TIAM1 LRP12 FBXO30 DIXDC1 UBE2D1 MEGF9 G3BP2 ZNF471 ZDHHC21 NPAT FDX1 CEPT1 KIT C20orf203 CAMSAP2 C21orf91 RORA FAM13B ZFPM2 PUM1 RNH1 TOX2	down	***
GO_ACTIN_FILAMENT_ORGANIZATION	0.0002029	0.0034897	0.5188481	-0.2543179	-1.455329	319	SWAP70 PHACTR1 DLC1 WNT4 EMP2 RDX GPR65 ARHGEF15 SHANK3 TMOD3 CGNL1 INPP5K BAG4 KANK3 CORO1C MYADM BAIAP2 CDC42EP2 ESAM S1PR1 CDC42 NEDD9 CIT RHOA CORO6 SPIRE1 LCP1 RGCC SFRP1 SPTBN1 ARHGEF2 TCAP SORBS3 RHOB ROCK2 ARRB1 SYNPO SORBS1 ROCK1 VASP MYO1B COTL1 C9orf72 ACTR3 CAPZA2 WASF3 PLEK DSTN RUFY3 ADD1 ACTR2 LMOD3 HCK MTPN SRF NCKAP1L ARHGAP17 KANK1 MYO1C FAM107A TMOD1 WASF2 SYNPO2 RHOBTB2 RAC2 ARHGEF10 RHOG RHOJ PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 CAP1 PPM1F ESPNL SNX9 RHOQ	down	**
HALLMARK_UV_RESPONSE_DN	0.0031098	0.0299409	0.4317077	-0.2883899	-1.455306	135	DLC1 PPARG INSIG1 BDNF FYN CAV1 CITED2 DYRK1A NR3C1 TGFBR3 TGFBR2 ATP2B1 PTPRM AKT3 ZMIZ1 PTPN21 KCNMA1 DAB2 TJP1 GRK5 NFKB1 NR1D2 DUSP1 SMAD7 NEK7 MAGI2 APBB2 PRKCE CELF2 SPOP PHF3 ATXN1 LTBP1 RXRA PDLIM5 TFPI KIT PTEN LDLR YTHDC1 KALRN CDON SERPINE1 PEX14 CDKN1B	down	*
GSE14415_INDUCED_TREG_VS_TCONV_DN	0.0055473	0.0462329	0.4070179	-0.2841948	-1.455082	146	CD55 ST6GALNAC3 SMIM12 OTUD1 YPEL5 FAM49A B3GNT5 LATS2 CHMP1B FOXP1 PRSS12 ADRB2 SPRY2 PPP1R13B CRTAM PPP3CC PSTK TCP11L2 PLEKHM3 KLF7 NR1D2 CCND2 DNTTIP2 IL7R CRIM1 MYLIP GABARAPL2 MAML2 SNX29 JUNB ELOVL7 BAG5 FOXO3 KLRC2 ZRANB1 PIK3C3 TBRG1 MICU3 IQSEC1 GIMAP5 ZBTB25 TDRP TRAF1 MBD5 NHLRC3 FOXJ2	down	*
GSE9006_1MONTH_VS_4MONTH_POST_TYPE_1_DIABETES_DX_PBMC_UP	0.0024497	0.0249881	0.4317077	-0.2787388	-1.455061	158	MIR22HG BMP2 GPC5 FIG4 AQP9 INPP5A BCL2A1 TRIB1 TEX2 LRRFIP2 TNFRSF8 MTF1 EMILIN2 IFI30 PTX3 HLX SLC19A1 TFRC KLF4 RBMS1 P2RY2 CARS2 GNAQ MAFF ANXA3 LIN7A CREM SGK1 TULP2 HK3 CTSZ CD83 HERC2P3 GCNT4 PTP4A1 MARC2 MME KIAA0232 MCUR1 TPMT PIM1	down	*
RACCACAR_AML_Q6	0.0016922	0.0188188	0.4550599	-0.2661719	-1.454898	210	GPD1 SLC31A2 SLC12A6 GPR15 PPARG CLDND1 TRPV2 OSCAR MSRA CBL AGPAT4 ZEB2 ERG LIFR SWT1 PICALM CNTD1 HLX GPBP1L1 ZBTB8A ARHGEF2 FLI1 ID3 DAB2 MAFG CCL4 FCER1G EVI2A TBX5 ADAMTS8 IL7R PAFAH1B1 MIR17HG FOXN3 ETF1 RYBP BCAR3 RHOG PIK3R1 REL PDZD2 RASSF2 SRSF4 CD6 CDC37L1 TAGAP DOK2 CCR1 STON1 CRY1 LTBP1 AMD1 SLC43A2 SPIB ZBTB25 NSUN4 SREBF2 JMJD1C SCAI GPR171 FGFR1 FAM13C	down	*
SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN	0.0048804	0.0419769	0.4070179	-0.2884085	-1.454791	131	CXCL3 CYP4B1 INSIG1 ENG CITED2 TGFBR3 CD9 IL1RN SEMA3B MALAT1 KLF6 STOM RGCC NFE2L2 CYBRD1 SDCBP CTSD CCL3 ATF3 PNRC1 BTG1 AQP3 LAMB2 GLUD1 IFNGR1 ACSL1 FOS MME VAV3 SOD2 KYNU RGS2 PLEKHO2 GEM BNIP3L SESN1 TFPI CDKN1C ALDH6A1 SCPEP1 S100A4 DAPK1 NFKBIA PTEN CREG1 LPAR6 EGR1 ZBTB16 CAPZB S100A8	down	*
GSE36009_WT_VS_NLRP10_KO_DC_DN	0.0019530	0.0210552	0.4550599	-0.2718775	-1.454492	187	SWAP70 SOWAHC GPR65 C5AR1 BCL2A1 GIMAP6 AVPI1 CD33 ADAM17 ZBTB21 CLN5 MED26 ARHGEF2 SPI1 RHOB ACSL3 CDK9 MAFG KLF7 TMBIM1 NFKB1 PIK3R5 SMNDC1 CD300LB SIAH1 METAP1 SEC14L1 HECA NECAP1 SERPINB8 ETV3 MTMR14 FOXN2 SKIL YPEL2 SRSF6 TRAPPC10 IRF5 METTL14 TESK2 TSC22D1 IFNAR1 STK40 RNF2 RBL2 IER5 MEX3C RASSF8 ZDHHC5 MCOLN2 DLST SLC16A10 HERPUD1 JDP2 NAF1 RBMXL1 LHFPL2 FHOD1 EYA3 KMT2E PIK3CG SURF6	down	*
MILI_PSEUDOPODIA_HAPTOTAXIS_UP	0.0000730	0.0014841	0.5384341	-0.2467612	-1.454490	435	MRPS18C MNDA PTP4A2 NUP54 TXNL1 QKI CYB5R3 IDI1 MEF2A NR3C1 AGTPBP1 WBP4 RBM7 UBR3 STARD4 TRA2B RAP1A BZW1 ZDHHC2 SERPINB9 PPP3CA KANK2 ZEB1 UBE2D3 EXOSC9 KIF1C MTMR6 SCP2 HNRNPA3 LIMS1 ROCK1 ATP6V1D ZNF24 CCND2 SS18L2 CAPZA2 PIK3C2A PAFAH1B1 BCLAF1 KPNA3 USP16 EFR3A TAF13 ACTR2 TOPORS SACM1L MTPN GPBP1 MOB4 RYBP ASNSD1 COPS2 PNO1 RBM34 SNAP23 RAB8B RWDD1 SRSF3 SF3B1 DNAJA1 TBC1D12 FYTTD1 MBNL2 OGFRL1 NAA30 CELF2 AGFG1 CACYBP PTP4A1 YTHDF3 MAPK8 CHPT1 PBRM1 STRN DCAF5 KCTD10 CRYZL1 VAMP4 SBF2 YTHDF2 RPL21 CNOT7 ORC2 SLIRP HNRNPH3 MBNL1 ARPP19 CCNH RNF138 C3orf38 YAF2 CTTNBP2NL RAB5A PIP4K2A CYB5R4 VPS4B TRAPPC8 DIXDC1 HNRNPK COMMD8 CUL3 TLK2 CAMSAP2 PSMD6 FAM13B NAA15 GSPT1 EIF4G2 PPP1CB ZNF326 YTHDC1 PSIP1 TSTD3 CFL2 HMGCS1 ATF2 CRBN SSB CLOCK SH3GLB1 FBXW2 FAR1 CSNK1G3 DNAJB4 PPWD1 SYCP3 YWHAB SRSF11 PPFIA1 CAPZA1 MATR3 ESCO1 CUL2 CRIPT FNDC3A WWTR1 WDR26 SLU7 BBIP1 SREK1IP1 UFSP2 CCNC PJA2 SKP1 BTBD1 MYO5A LARP7 MRPS14 IVNS1ABP UBE2D2 AP4S1 GNL2 SUCLA2 AASDHPPT TANK EIF3J	down	**
GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0030124	0.0292482	0.4317077	-0.2744827	-1.454201	173	ST8SIA6 HVCN1 HSD17B11 MYADM AKAP7 ATP2B1 SBDS ZDHHC2 HSPB1 ADAMTSL4 FLI1 IL10 MTMR6 SORBS1 ITM2B RRM2B NR1D2 SELL HOPX ARHGAP9 RNF139 PIK3C2A PPP2R5A CRIM1 EFR3A ZDHHC20 EMP3 SLC25A33 S1PR4 HECA RAB31 OSBPL9 MSRB3 CDK2AP2 RIN2 GIMAP1 OSGIN1 TEC ICAM1 SELPLG BNIP3L SESN1 IL18 SLC35D2 ZNF143 MMD C2orf42 GIMAP4 RNH1 HERPUD1 CLIP1 ENDOD1 CD79B IRF1 ITGA6 CCPG1 PLLP NIPAL3 AKAP13 TTC39B RNF19B MYO1F CRLF3 SLAMF7 CAPG SLAMF1 PLCL1	down	*
CTACTGT_MIR199A	0.0035203	0.0330771	0.4317077	-0.2764699	-1.454169	164	SECISBP2L BMP2 CITED2 CALCRL QKI CDC42 GALNT18 CBL ZBTB4 LIFR C1orf21 BZW1 FOXP1 PTX3 CAMTA1 NFE2L2 AKT3 ZEB1 GPM6A SIK2 ATF3 UXS1 RNF139 ZNF706 AKIRIN1 TANC1 SNN SRF RBM39 PDIK1L RNF141 CPEB4 PI4K2B GFPT2 FOS CDK17 BTBD7 AP1G1 TGIF1 PDS5B BAZ2B APLP2 PHLPP2 MBNL1 RBL2 TAB2 MAP3K4 RAB2B NRP2 NAA15 EHD3 YTHDC1 PLAG1 ZNF654 ATP1B1 CCNT2 ADAMTSL3 CTDSPL2 C6orf62 GOLGA8B	down	*
GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN	0.0020527	0.0218807	0.4317077	-0.2734120	-1.453871	176	CXCL3 CCM2L SLC39A8 CDC42EP2 BCL2A1 FAM49A RFTN1 ASAP1 SLC7A7 BEST1 HECW2 TNIP3 PTX3 HLX SLC7A11 ZNF697 LAIR1 SLC25A37 BTG3 CASP5 PLAUR DENND3 SOCS2 P2RY2 CXCL2 CCL4 FCER1G ALOX5AP N4BP1 HCK IL6 MAML2 PLEKHA3 ETV3 HRH1 MN1 TREM1 ELOVL7 FERMT2 ACKR3 PI4K2B FSD1L ATP13A3 CXCL5 TNFRSF9 ACSL1 PIK3AP1 AZIN1 FPR2 SOD2 KYNU CCL20 ICAM1 MIR155HG IER5 MT1M TRAF1 PLGRKT MAP3K4 MCOLN2 SAMSN1 MT2A	down	*
GO_MYELOID_CELL_DIFFERENTIATION	0.0002781	0.0045823	0.4984931	-0.2531524	-1.453751	334	EPAS1 CLEC1B CD101 TAL1 KLF13 PPARG GATA2 SNX10 DCSTAMP OSCAR PDE1B TMOD3 CDC42 TGFBR3 TET2 TGFBR2 TRIB1 LILRB3 IL23A CASP9 SH2B3 RASGRP4 KLF10 FOXP1 ASH2L GATA3 RB1 TRAF6 SFRP1 SPI1 TFRC FLI1 EVI2B AGO4 AGO3 THBS1 CEBPA MPL CCL3 ID2 TLR4 FCER1G LYAR INHBA UBASH3B PAFAH1B1 ADD1 SRF NRROS NCKAP1L RBPJ WASF2 PKNOX1 PSEN1 JUN MITF GABPA CUL4A ETS1 TYROBP HSPA1B JUNB OSTM1 DNASE2 CCR7 SP3 PIK3R1 PABPC4 IRF8 GPR183 CREB1 SIGLEC15 FSTL3 RASSF2 SNRK FOS KLF2 FOXO3 KAT8 CD74 TGFB1 EPB42 JMJD6 CBFA2T3 CD81 LGALS3 MEIS1 CCR1	down	**
GO_HEART_MORPHOGENESIS	0.0012453	0.0150511	0.4550599	-0.2661615	-1.453029	211	SMAD6 RBP4 TMEM100 ACVRL1 FOXF1 SOX18 TEK DLC1 CCM2L TBX3 BMP2 ENG FOLR1 SOX17 CITED2 BMPR2 S1PR1 TGFBR3 TGFBR2 HEG1 TBX2 GATA3 WNT3A TCAP FOXC2 NODAL ZMIZ1 SNAI1 TNNC1 GAA CLDN5 SEC24B ID2 SMAD7 ZMPSTE24 TBX5 DCHS1 HES1 MIR17HG TGFB2 SRF RBPJ PSEN1 JUN NOTCH1	down	*
GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP	0.0020604	0.0219430	0.4317077	-0.2744172	-1.452303	172	TNR PNPLA6 LMO2 CYB5R3 CLEC10A IL1RN RCHY1 TXNIP ATP2B1 RANBP9 PICALM ABCG1 ANPEP SPRY2 HNRNPU MAPK8IP1 FLI1 ADO ID3 SLC7A8 ABCC4 SMAD7 DEGS1 PRCP RBPJ PPP2CA BCAR3 SEC14L1 DHH CYCS DDX5 CST7 NDST1 PPM1F CD151 PTP4A1 XYLT1 HNRNPA2B1 KIAA0232 CD1D ATXN1 DOK2 CCR1 STX12 PHF2 MBNL1 TBC1D1 CTSC TIMP3 GNMT PAK2 GSPT1 INTS10 KLC1	down	*
GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN	0.0047684	0.0411662	0.4070179	-0.2735616	-1.452297	174	OLR1 SOWAHC CPEB2 CLEC3B GPR65 LPL CD44 LY86 PRKAR1A ITGA5 ANXA5 CST3 IL10 MSR1 MAP2K3 BST1 ZFAND5 CLIC4 DUSP1 CD300C IL7R MTPN YBX1 SENP3 ATP11A APBB2 RCAN1 PTGER4 SKIL CGGBP1 CDK14 RHOQ PELI1 PSMD12 EHD1 TMEM230 IRS2 KCNA3 RGS2 BMP2K RNF138 RTN4 CDKN1C CYB5R4 CUL3 RNF38 LYST FGFR1 GSPT1 SPATA13 PPP1CB EGR1 C1QB FJX1 CTSH ZBTB16 CAPZB CLEC4E SSB ZFP36 NOG EFNB2	down	*
GO_POSITIVE_REGULATION_OF_IMMUNE_SYSTEM_PROCESS	0.0000003	0.0000141	0.6749629	-0.2300957	-1.451770	908	SIRPB1 RBP4 NLRC4 EREG CD300LF FOXF1 HMOX1 SWAP70 FCN1 CD101 GCSAML SCIMP TAL1 CD55 FCN3 GATA2 SPN PGC IL1B MNDA DCSTAMP LPXN BTNL9 FYN HCAR2 CAV1 BAIAP2 PRAM1 MYD88 ELF2 PLEKHA1 C5AR1 CLEC10A RBM14 FGF10 ELMO1 CDC42 MARCO IL1RL1 CD1C GAS6 OTUD4 PSMD5 LAMP1 CD22 SLC11A1 TGFBR2 TRIB1 RFTN1 IL23A FGR RHOA CD36 ANXA1 MIR146A PLA2G7 SPG21 CLCF1 IGKV2-28 CD5 ADA ADAM17 RAP1A CLEC7A MASP1 TNIP3 MAP3K8 RNF125 KLF10 FOXP1 HLX PAG1 MS4A1 IFNK GATA3 SIRPA RB1 RGCC IL18R1 TRAF6 CRK CRTAM WNT3A PDE4D UBE2D3 TFRC ZMIZ1 EVI2B IL10 CFD DUSP3 BIRC2 BST1 SLC46A2 PTAFR THBS1 CEBPA CLECL1 SOCS5 MPL LY96 FAM49B UBQLN1 CCL3 NFKB1 CDKN1A CADM1 PTPRC IRAK2 SELP AXL ID2 CCL4 JAM2 TLR4 IGFBP2 ACTR3 SFTPD XCL2 FCER1G INHBA OXSR1 IL7R HLA-DQA1 HES1 C4BPB AKIRIN1 ACTR2 TGFB2 HCK NCKAP1L IGLV2-11 MYO1C CD80 ELF1 IL6 WASF2 MUC3A CD160 CTSS PSEN1 APPL1 AQP3 SEC14L1 C1QA JUN PSMA1 ETS1 RAC2 TYROBP HSPA1B RAPGEF1 CCR7 STX7 ATXN1L DAPK2 PIK3R1 CD83 PRKCE GRB2 GPR183 CREB1 MALT1 RC3H1 PRKACA DOCK8 AP3B1 TBX21 IGKV3-20 PLCG2 FOS UBB PELI1 TNFSF13 PSMD12 RUNX3 FOXO3 ICAM2 TREX1 CD74 CR1 PIK3AP1 SMPDL3B TGFB1 VAV3 AP1G1 CD1D ZBTB1 CD6 TEC FPR2 NLRP6 MIA3 PIK3C3 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 BAG6 CCR1 FCGRT N4BP2L2 ADAM10 PDE4B IGKV1D-39 CCL20 UNC13D CCR6 ICAM1 TRAC IL18 IL18RAP LAT ARPC2 ARRB2 RTN4 HSP90AA1 TAB2 RIPK2 NLRP3 UBE2D1 ACTB HAVCR2 PSME4 CREBBP ICAM3 CD19 TLR10 SIN3A NFKBIA CTSC CD1E EDN1 CD3G ARPC5 PAK2 KLRK1 TNFSF9 AIM2 THEMIS2 ITCH PSMD6 PSMD9 SFPQ	down	***
MIR1250_3P	0.0000865	0.0017062	0.5384341	-0.2473425	-1.451545	427	SLC6A4 FFAR4 SMAD6 GAPT ATXN3 GREM2 LIPA LRRFIP1 PTPRB TTC7B INSIG1 LPL THAP2 QKI GPCPD1 BMPR2 NR3C1 FUCA1 MOB1B RFTN1 SCARA3 SPCS3 ZEB2 ARHGAP29 MYOZ1 B3GNT5 SLC36A4 RAB33B PICALM CAMTA1 SRSF2 LAMTOR3 AKT3 TFRC MYCT1 ATP6V1B2 PTPN21 CCDC82 DGKE KCNMA1 LIMS1 YBX3 MYRIP ATL3 LBH ARL4A DSTN PAFAH1B1 NUS1 TBC1D4 ZDHHC20 FAM102B LACC1 SCEL PDIK1L CREM DNAJC27 PLGLB1 EBF2 EBAG9 CABLES1 RAB8B PDCD6IP TMTC1 HMBOX1 GABPA ADRA1A CNTN4 APBB2 IPO7 SNX2 SKIL CREB1 COBLL1 RC3H1 LPCAT2 ZNRF3 ZNF597 SMIM20 OGFRL1 MOB1A RRN3 RHOQ CALM1 PKIA TRAPPC10 KLRC2 ZFAND6 NIPA2 ATG2B PDS5B VAMP4 FEM1B PDE12 GNAI1 MAP3K2 PCDH17 RIMKLB AMD1 BMP2K RBL2 RNF138 CHURC1 YAF2 FKBP1A TMOD2 EPHA2 ZDHHC21 SRSF10 KPNA4 RBMS3 ING2 BCAT1 SCAI DNAJB9 C21orf91	down	**
TATTATA_MIR374	0.0007763	0.0104473	0.4772708	-0.2639547	-1.451303	237	SMAD6 BMPER BMP2 QKI SRSF7 VAMP2 NR3C1 SCN5A CCNL1 ZEB2 NUMB BRINP3 NFIX FOXP1 PAQR3 DACH1 GATA3 SPRY2 PDE4D GPM6A IL10 TLE4 FOXO1 ZCCHC24 ZNF423 MGAT4A PNRC1 CAPZA2 CLIP4 CYP26B1 HES1 AFF1 CRIM1 BACE1 VCPKMT NCOA1 SERTAD2 MOB4 PKNOX1 PIKFYVE CPEB4 CNTN4 DUSP8 SP3 MBNL2 RC3H1 HOMER1 DENND4A PELI1 HIVEP2 YTHDF3 FOSB PKIA C16orf72 ATXN1 MEIS1 LTBP1 ADAM10 PDE4B AMD1 LDLRAD4 FKBP1A SF1 TRAPPC8 MEX3C ZDHHC5 RNF38 ABCA8 CAMSAP2 BANK1 EIF4G2 STARD13 PLAG1 DUSP6 NR4A2 KIAA2026 NOG WNT5A PDE7B RNF214 EP300 DR1 MEF2D SETD2 FNIP1 NR4A3 METRNL NTF3 NFKBIZ	down	*
MIR3714	0.0000575	0.0012118	0.5573322	-0.2502997	-1.451085	386	SLC31A2 SEMA6A PHACTR1 RDX DPYSL2 MBOAT2 PID1 ARRDC4 RCOR1 RGS9 VAT1L QKI ELMO1 CBL SH2B3 ASAP1 TTL LMNA MTF1 BTG2 ZNF503 ANXA5 LITAF FOXP1 LCP1 SLAIN2 ADRB2 TNS1 EPM2AIP1 SETD3 PTPN12 EFCAB14 AMOTL1 SCP2 DAAM2 ROCK1 ZFAND5 SLC7A8 ADAMTS9 TPP1 MYRIP SPAG9 SNIP1 CDKN1A PIK3C2A CUL5 MPC1 ZNF706 FKBP15 BACE1 TLL1 MTPN USP25 RBM39 MYLIP RBPJ MYO1C CREBRF GZF1 RYBP PHTF2 MITF CCDC3 VAT1 NOTCH1 HMBOX1 HRH1 DESI2 JPH1 BTD CCDC50 CYCS APBB2 FERMT2 PCGF5 MAPK4 SLC10A7 ZNRF3 FAM177A1 THSD7B ACSL1 RHOQ CD164 MBP XYLT1 PEA15 MCUR1 ANKRD12 MACF1 MLANA SMAD2 GLTP MOB3B PDLIM5 MIER1 FKBP1A ELOVL1 DCTN4 SDAD1 ULK2 LYSMD3 KATNA1 LIMCH1 RASSF8 PDE4A ARPC5 MMD ANXA11 TMCC3 NR3C2 IQGAP1 EIF4A2 EVI5 TRIM36 PAPSS2 REEP1 SUGT1 CHP1 CDON	down	**
GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN	0.0031515	0.0302894	0.4317077	-0.2757661	-1.451023	168	SIRPB1 C18orf32 MIR22HG TXNL1 RTN3 PRPF38A WBP4 SCARF1 SPCS3 SPG21 SLC36A4 MALAT1 CRK DIABLO GMEB1 AGO3 COQ10B GRK5 AKIRIN1 HEXB MOB4 COPS2 ZFP91 RABGAP1 VPS26A TMEM251 HSPA13 SMU1 MORC3 UVRAG DYM TPRA1 CD164 EMC7 PPP2CB ADPRM AKIRIN2 TESK2 KHDRBS1 CEP170 SETDB2 RAB5A TRAF1 C17orf49 WDFY3 RNF13 RAB2A ATP11B CCNK NDFIP1 TBC1D23 COX20 DNAJB1 LAMTOR5 CCDC93 GABPB1 ANKHD1 CRIPT UFSP2 DERL2 CAPN7 TPST2 FBXL13 ST3GAL1 EIF4A3 HSPA5 RASA2 DNAJB6 MAPK6 EMC2 PRNP APPBP2 GPS2 NUDT21 GID4	down	*
GSE20715_WT_VS_TLR4_KO_24H_OZONE_LUNG_UP	0.0036216	0.0337566	0.4317077	-0.2758388	-1.450849	164	SLC12A6 TSPAN4 EMP2 GREM2 LIPA FIG4 ALAS1 FBXO3 ACSM1 EPB41L3 TGFBR2 PILRA PDCL RHOA RRAGC PCYOX1 ABCG1 RBM4 NFE2L2 PDGFA PER3 CCDC82 MEFV TSPAN12 FAM76A RRM2B USP2 PER2 NR1D2 CD302 SMAD7	down	*
GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN	0.0037526	0.0345716	0.4317077	-0.2823833	-1.450254	142	GPD1 ACP5 SGK3 ODF3L1 SNX32 IDI1 APIP OTUD4 SPCS3 ANXA1 TRA2B PICALM ADRB2 SRGN ATP6V1H CCNI CSRNP1 FOXO1 ZFAND5 CEP57 RAP1GDS1 BTG1 PKIG YBX1 HCFC2 DESI2 RAPGEF1 IRF8 GMFG PRKCE PIM1 CSDE1 EXOC1 THAP11 TAGLN ARAP2 SESN1 SF1 CXCR4 SSH2 CECR2 FEZ2 DNAJA2 ARHGEF18	down	*
MIR5197_5P	0.0035783	0.0334785	0.4317077	-0.2767734	-1.449950	157	IL1A LYVE1 RDX CLDND1 ZBTB34 TXNL1 UBR3 KIAA0355 ADAM17 PCYOX1 LUZP1 GLS MAPK8IP1 FBXO8 UNC45B SORBS1 LIMS1 KLF4 PDE8A ERP44 MGAT4A SEC31A CNOT6L VAMP3 PHACTR2 MAGI2 LRCH1 SHOC2 FOXN2 MAPK4 ATL2 MSANTD2 STRN SKIDA1 ZBTB11 MBNL1 ARPP19 BNIP3L INTS6 EPHA4 ZBTB25 PSME4 SRSF10 MAP3K4 MARC1 SFPQ ANO6 PLAG1 SAP18 ATF2 CLOCK ITGB1 CMPK1 NDFIP1 CTDSPL2 ATP8A1 FNDC3A SKAP2 ATF6 PIGP GJB2	down	*
MORF_DAP3	0.0058813	0.0481765	0.4070179	0.3207783	1.449915	170	NIPSNAP1 EIF2B5 CCT2 RUVBL2 SDHA CBX3 ZNF146 ALG3 ANAPC5 CCT3 KXD1 SNRPE DDT RTCB EIF6 POLR2H ILF2 SNRPA COX7C TCEA1 DAP3 PSMD2 JTB COPS6 CCT7 PSMB3 BRD8 STOML2 AHCYL1 ACLY TMEM147 HAX1 AATF POLR2I PSMB4 SMARCC2 EIF3K NDUFV1 BANF1 PDAP1 COX5B FBXW11 MRPL9 SRP9 SNRNP200 DNPEP TBCB TBL3 GPN1 COX6B1 PRKAG1 LYPLA1 CLNS1A DRG1 DGUOK FAM120A NELFB HUWE1 CS XRCC5 HNRNPAB LRPPRC SRSF9 PPP2R1A COX6A1 DDX49 FIBP PSMD8 IK BUB3 ATXN10 RPP40 HNRNPUL1	up	*
MIR6882_5P	0.0037526	0.0345716	0.4317077	-0.2822788	-1.449717	142	SMAD6 WEE1 TEK SOWAHC PTPRB EPB41L3 TRIB1 SEMA6D C10orf25 UBE2D3 TIPARP SOCS5 MYO1B MGAT4A UBE2E2 TM9SF2 AKIRIN1 TANC1 EFR3A MYLIP RYBP ETV3 MITF SKIL LSM1 CXCL5 SLC25A24 PTP4A1 GIMAP1 ZNF521 KCNA3 ARPP19 EPB41L5 ARIH1 ISCU TBCEL NFKBIA FAM126B DLST PUM1 SPOPL EIF4G2 DUSP6 MAPK1 ATP1B1 UNC50 RCSD1	down	*
GO_VACUOLAR_MEMBRANE	0.0001089	0.0020770	0.5384341	-0.2547319	-1.449349	341	SIDT2 MCOLN1 TMEM150B RAB44 SPNS1 THBD PCSK9 TMEM138 ARL8B SLC15A3 MANBA VAPA LAMP1 SLC44A2 MAN2B1 RRAGC SLC3A1 RILP LITAF CYB561A3 ANPEP CLN5 ABHD6 STOM GRN LAMTOR3 ATP6V1H RAB14 ATP6V1B2 CYBRD1 ARRB1 RAB12 AHNAK SLC12A4 CDIP1 DAB2 GAA DRAM1 MAP1LC3B ATP6V1D SPAG9 CTSD TMBIM1 LAPTM5 HPSE ATP6V0D2 M6PR TM6SF1 GNAQ HLA-DQA1 LMBRD1 CMTM6 PI4K2A HGSNAT PRCP TMEM9B GABARAPL2 PSEN1 ATP6V0B ATP11A OSTM1 STX7 GLIPR1 ENTPD4 AP3B1 UVRAG CLN3 TMEM192 SLC3A2 ATP6V0D1 CD164 NAPG CD74 SORT1 AP1G1 CD1D SBF2 MTMR2 GNAI1 ATP6V1A ATP6V0C GNB4 GABARAPL1 BRI3 VPS39 MFSD12 CLCN6 BLOC1S2 CALCOCO2 GIMAP5 HSPA8 SNAP29 MMD LDLR WDFY3 RNF13 RAB2A ZFYVE26 ATP6V0A1 SPPL2A TMEM30A ATP11B LNPEP SH3GLB1 RAB37 DRAM2 FPR1 SLC26A11 NFAM1 YWHAB WDR41 LAMP3 SNX14 HLA-DRB1 LAMTOR5 GPR137B	down	**
GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_DN	0.0040077	0.0362223	0.4070179	-0.2728356	-1.449278	179	SOWAHC WDR74 FLVCR2 MYD88 FXYD2 IL1RL1 VAPA ABCB1 IER2 TXNIP COQ7 LITAF ZEB1 TIPARP FLI1 STAT5A TRIM46 ZFAND5 TMBIM1 FMNL3 P2RY2 UBE2B N4BP1 HCK HESX1 GLUD1 RAC2 JUNB ATP11A PTGER4 PIK3R1 IRF8 PTGER2 SNX1 CAP1 TNFRSF9 SMIM20 RASSF2 LGALS2 MOB1A AZI2 HIVEP2 YTHDF2 EWSR1 IST1 BNIP3L GLTP RNF138 CEBPD TIAM1 OSER1 LDLR FAM13B MT2A SPSB1 CNR2 ZYX ZFP36 ATP1B1 EBF1 UBE2W	down	*
MIR7_2_3P	0.0000221	0.0005468	0.5756103	-0.2394062	-1.449167	546	GPR17 TAL1 CPEB2 DPYSL2 RAB3C KCTD9 LRRFIP1 TMEM170B BDNF CCDC88A DDX6 THAP2 SLC39A8 PRKAR1A TGFBR3 EPB41L3 ABCB1 TMX4 RBM7 SLC7A7 BZW1 PICALM EIF4E TOR1AIP1 PPP3CA PLXNA4 TRAF6 NFE2L2 TMEM41B ZFYVE16 PDE4D PDGFA GPM6A GMEB1 CSRNP1 PER3 HNRNPA3 BNIP2 UHRF1BP1L MVB12B MED6 MPL FBXL3 MGAT4A PDE3B NPAS3 CXCL2 AQP4 PNRC1 EPS15 CCSER2 RNF139 WDR48 N4BP2L1 WFS1 PEAK1 MPC1 PRICKLE2 TM9SF2 CYP26B1 BCLAF1 SMNDC1 ACTR2 SIAH1 C2orf69 TOPORS UFM1 SPIN1 TMPRSS11A SCEL CCNY ELF1 SYNPO2 KIF13A EBF2 NEK7 HCFC2 SEC14L1 SF3B1 OXNAD1 CPEB4 PDE5A CCDC50 FOXN2 VPS26A TBC1D12 SKIL EEA1 MBNL2 ATL2 RC3H1 MFAP4 FSD1L GRIA1 SLC10A7 CDK14 AGFG1 SLC25A24 ADNP2 PELI1 PTP4A1 HIVEP2 YTHDF3 AZIN1 CC2D2B TMX3 KIAA0232 PDS5B ABHD13 CNOT7 MAP3K2 PHF19 PPP3R1 GNB4 HINT3 RIMKLB ACYP2 INO80D RNF138 FGF2 PDLIM5 CEP170 HSP90AA1 LRP12 TMOD2 FBXO30 CREBBP RBMS3 STAM2 THRAP3 MCOLN2 PRKG1 CYTH1 PAIP2 CAMSAP2 FAM13C NAA15 ENDOV WDFY3 EID1 MACROD2 RAB2A MIER3 DMXL2 REEP1 KALRN MB21D2 SLC19A2 DCUN1D3 ITGB1 CMPK1 HP1BP3 CCNT2 CTDSPL2 AQR SRSF11 PRTG FPR3 PIAS2 MTSS1 GPR137B EXOC6 RCSD1 GABPB1 STX16 ARHGEF12 ATP8A1 TMEM220 ARHGAP44 SKAP2 MEF2D RNF111 SETD2 ROBO2 SREK1IP1 EDIL3 FNIP1 PTGS2 IMPACT EML5 YOD1 PJA2 PTPRA DCAF13 SCAF8 IREB2 SENP6 CBLL1	down	***
GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN	0.0055422	0.0462113	0.4070179	0.3207051	1.449089	172	CEP72 CDC45 CHEK2 BRCA1 CDK4 CENPA CDC6 TPX2 UMPS SRPK1 NCAPD2 MRPS35 AP1G2 SPDL1 LDHB NUDT1 C9orf116 PAFAH1B3 CCDC77 SAE1 MPHOSPH9 KIF11 C7orf50 DCTPP1 BRIP1 IDH2 ALDOA C12orf75 ASF1B RFWD3 NEIL3 ANAPC7 DAP POLR2H AGL GPR68 TACC3 AARSD1 CASP7 GAS2 C15orf41 PTER PFAS AAAS RPUSD1 RCC1 HAUS4 LHPP STK35 TCERG1	up	*
MIR548AU_3P	0.0058367	0.0479034	0.4070179	-0.2829987	-1.448957	146	FAM167A PHACTR1 RDX MED4 CDH13 MTMR10 C3orf70 PKHD1L1 MTF1 CAMTA1 CRK NPNT FAM76A MGAT4A PER2 FCER1G ELMSAN1 RAP1GDS1 OXSR1 GNAI2 C2orf69 FOXN3 FAM107A FMNL2 BMP3 SHOC2 FOXN2 TMEM251 EEA1 HSPA13 MAPK4 ZNRF3 SMIM20 GPRIN3 RRAS MBP	down	*
GSE17721_LPS_VS_POLYIC_8H_BMDC_DN	0.0043250	0.0384259	0.4070179	-0.2737716	-1.448943	169	SLC6A4 CYP27A1 LYL1 INPP5K SAMHD1 MKNK1 FGR SLC44A2 AHRR IFI30 PARVG ABHD6 TFEC TIPARP FBXL3 PMM1 LRRC40 HNRNPUL2 VIM TLR4 PNRC1 PIK3C2A GCA PIAS1 STK24 SLC25A3 STAT4 HIC1 EPC1 HOMER1 TSSK6 RBKS FOXO3 ATG3 WNT11 NAP1L5 ITGA9 SERPINB1 DOK2 BRI3 TOB1 THAP11 PHF2 DBNDD2 IL18RAP SERTAD1 PALD1 GLUL ACADM MCOLN2 CYTH1 IQGAP1 RNH1 SMAD4 REEP1 GREM1 TRMT1L S100A8 MICAL1 SLC9A3R2 DAPP1 HMGB1	down	*
ZHANG_BREAST_CANCER_PROGENITORS_UP	0.0009089	0.0117788	0.4772708	0.2968845	1.448478	391	TRIP13 TP63 HELLS BUB1B NUP107 PROM1 CENPF CPSF6 PBK TTF2 PHF14 DEPDC1 BRCA1 BET1 CDCA7 ANLN CDCA8 ECT2 CDC6 FIGNL1 RBBP8 UHRF1 MCM2 CDC25A CA12 NCAPD2 LSM5 ITGA2 MELK CEP55 TP53BP1 BUB1 TOP2A AURKA NUP155 WDR3 ATR KIF2C CD2AP RRM2 TRRAP HOOK1 GPSM2 PFN2 CD24 TOPBP1 CHEK1 DNAJC9 ACTL6A AHCY DDR1 GRHL2 TULP3 SKP2 PARP1 TNIK SSBP1 SERTAD4 C1orf112 GMNN POLR3K UNG NCAPG PRR14L ENPP3 PSAT1 ANKRD26 PDK1 EZH2 POLR1C ACTR3B ARNT2 FGFR1OP RNF44 EFTUD2 VBP1 CEP192 TRIM37 C1orf131 ZNF239 ESCO2 ANP32E PKP4 TCEA1 EDARADD SAP30 ANAPC1 NUP85 PLEKHB1 CLDN12 GEMIN6 EFCAB7 RPA1 ZNF160 MRPS33 LSM7 EDAR ATAD2 PATZ1 GTPBP10 STRBP CCNA2 PRIM1 TMEM117 VDAC1 SHCBP1 CEP164 RAD51 FARSB OXCT1 RPRD2 NME7 RNF7 VDAC3 SMC2 MTHFD1 PAICS TTC9C NCAPD3 ARMC10 PWP1 ZC3HAV1L E2F7 TAX1BP1 ZNF367 LMBRD2 CD38 VPS26B PDZD8 AKAP9 RBL1 TRPS1 TMPO MPZL1 CRYZ TASP1 PABPC4L MLLT3 SLC20A2 SHMT1 TRIM59 ZNF532 POT1 GLRB XRCC5 NAE1 C1orf74 PPP2R1A NUDCD1 ORC5 POLD3 SMC4 METTL9 STMN1 IK HNRNPA1 SKA2 LRBA TTC3	up	*
GSE3982_MAC_VS_NKCELL_UP	0.0033314	0.0316621	0.4317077	-0.2721260	-1.448295	177	RAB11FIP1 HMOX1 STAC SLC47A1 FABP4 LYL1 BAG4 PCOLCE2 C5AR1 MSRA LAMP1 EPB41L3 TRIB1 NUMB HBEGF ABCG2 ANXA5 RGCC TNS1 ATP6V1H EPB41L2 CYBRD1 KIF1C FABP5 CCL22 SDCBP PLAUR PAQR5 RMDN3 ERP44 CDKN1A M6PR NRBF2 CMTM6 CLN8 RBPJ APPL1 KCTD12 CD83 ZNF804A	down	*
GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_UP	0.0045840	0.0400811	0.4070179	-0.2714358	-1.447726	183	ACP5 LPIN2 IL1A DENND5A FGD5 HCAR2 CCDC88A CAV1 ZCCHC2 STX11 BCL2A1 IL1RN AGPAT4 IGSF6 AVPI1 HBEGF ITGA5 MAP3K8 SLC7A11 CLN5 TUBB6 SLC7A2 PTPN12 CLIC4 CDKN1A ID2 PNRC1 PLEK PIK3R5 SPRYD7 KPNA3 RASGEF1B PROCR RBPJ SYNPO2 ESD STAT4 HSPA1B RCAN1 IFRD1 CD83 GPR183 MALT1 RC3H1	down	*
MIR3606_3P	0.0001959	0.0033805	0.5188481	-0.2571051	-1.447701	301	SLC6A4 PPARG PTPRB RUNDC3B TMEM170B JPH4 NEDD4L ELF2 RXFP1 WBP4 MOB1B EDEM1 ARHGAP29 CNST ZDHHC2 RANBP9 SPIRE1 SLC7A11 ZBTB8A PPP3CA ZFYVE16 UBE2D3 TMEM38B CYBRD1 PAQR5 ZFAND5 PDE8A PTPRC WASF3 KLRD1 SPRYD7 NUS1 CNOT6L LIN54 TOPORS ELF1 PDIK1L VPS37A SAR1A KIF13A APPL1 RAB8B SERPINB8 ARL6IP6 TBC1D12 EEA1 SP3 CREB1 RC3H1 FSD1L YWHAZ ZCCHC9 RNF146 AGFG1 CDK17 PTP4A1 YTHDF3 AZIN1 PPP2CB STRN NDUFA5 ABHD13 TSC22D1 FEM1B TRGC1 NAB1 TPMT ADAM10 CALB1 HACE1 RNF138 TXNDC11 ALDH6A1 HNRNPK ZDHHC21 RBMS3 MAP3K4 CUL3 RASSF8 TTC28 SCAI PTEN CHCHD7 SNX15 PRKG1 ITCH GSPT1 EIF4A2 HPCAL4 ZNF326 ABI1 KLF15 KALRN	down	**
PLASARI_TGFB1_TARGETS_10HR_UP	0.0027075	0.0268793	0.4317077	-0.2722271	-1.447426	175	EREG OTUD7A OLR1 KLF13 LRRC8C PRKG2 GREM2 LRRFIP1 EGR2 GFOD1 FOSL1 ABCB1 IER2 HBEGF ITGA5 IL18R1 PDGFA FOXC2 CNN1 CSRNP1 SNAI1 NRARP PLAUR NES ARNTL SOCS2 ARC INHBA MAFF HCK WNT9A FLT1 RNF149 IL6 PLK3 JUNB PPP1R15A PI4K2B FSTL3 GFPT2 IP6K1 MCAM WNT11 TGFB1 DUSP5 GPR84 CRY1 CCL20 HSPA2 FGF2 TIMP3 TMCC3 PMAIP1 SPATA13 PAPSS2 SPHK1 SERPINE1 FJX1 DUSP6 ENDOD1	down	*
MIR6124	0.0000837	0.0016602	0.5384341	-0.2489466	-1.447139	378	OTUD7A TAL1 PECAM1 ZC3H12C ATXN3 MBOAT2 PTPRB LDB2 NEDD4L BAIAP2 BMPR2 PAFAH1B2 YPEL5 P2RY13 C3orf70 MOB1B DDO ZEB2 SPG21 TACC1 MTF1 SPIRE1 CSGALNACT2 FOXP1 KLF6 GLS CAV2 PAG1 GPBP1L1 DACH1 ZNF365 SETD9 PLEKHM3 KLF11 ZFAND5 NR1D2 C9orf72 PAPSS1 ELK3 PTCHD4 ILDR2 KIAA0408 CRIM1 CNOT6L LIN7A RASGEF1B HGSNAT FOXN3 CREBRF CD80 CREM LRRTM2 COPS2 SLCO2B1 MAGI2 TMTC1 ETS1 OSBPL9 MSRB3 TREM1 FOXN2 APBB2 BAG5 GLIPR1 HUNK CLEC17A IDS CREB1 KBTBD8 RC3H1 MORC3 NAA30 CASZ1 EPC2 ZNF407 CDK14 ESPNL FOS SLC25A24 CDK17 USP7 XYLT1 RIN2 ZNF521 HNRNPA2B1 TSPYL6 RSBN1L TSC22D1 MAP3K2 ATXN1 MYOCD LTBP1 CSNK2A2 IST1 INO80D INTS6 ARPC2 SF1 SFT2D1 NBN MGAT2 BLOC1S2 ARIH1 BRWD1 HNRNPK G3BP2 GRIN3A BCAT1 MAFK PAK2 RORA RHOT1 ELFN1 MAN1C1 IRF2 SCLT1	down	**
MIR4773	0.0025952	0.0260977	0.4317077	-0.2771423	-1.446727	158	SEMA6A GCSAML TRHDE HVCN1 ZC3H12C LHCGR HSD17B11 CAV1 CBL SEMA6D ASAP1 CAV2 PLXNA4 PTPRO ANKRD10 TJP1 C11orf91 ITIH5 DPH3 CADM1 AXL KCTD20 LBH ZNF706 RABGGTB FAM102B CELF1 FYTTD1 PRKCE ATL2 CRYM PELI1 AGPS YPEL2 NECAB1 CCR1 ATAD2B SMAD2 AMD1 SIK3 BRWD1 CREBBP CEPT1 TMEM87A DLST KIF1B ZFPM2 ACVR1C OSGIN2 TRMT1L SV2B UBE3A RMDN1 PLN ROBO2 SIRT1 FNIP1 IRF4 KRT10 SKP1	down	*
GSE3920_IFNA_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN	0.0059060	0.0483325	0.4070179	-0.2813759	-1.446567	147	EPAS1 LPIN2 FYN CYB5R3 IL1RL1 GNPTAB FGR DNASE1L3 ZEB2 LRRFIP2 SEMA6D TACC1 ENTPD1 FOXP1 SPRY2 IL10 SORBS1 CASP1 GRK5 TMBIM1 ITGAX PEAK1 CRIM1 NDNF RAPGEF1 PTGER4 PODXL DAPK2 FRYL PHOSPHO2 ZCCHC9 TIGIT NKG7 XYLT1 PIK3AP1 SMPDL3B LRRC32 PLSCR4 CLDND2 MRGPRF IL18RAP MS4A4A ZBTB25 KLRK1 FNIP2 THEMIS2 SPATA13 KAT5 CD70 CX3CR1 CD109 ATP6AP1L PLXDC2	down	*
GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP	0.0021123	0.0223556	0.4317077	-0.2733300	-1.446549	172	OLR1 SOWAHC LTA4H FIG4 ZBTB34 TMEM170B LPL RTN3 ALAS1 MANBA LAMP1 SYNC TMX4 DNAJC3 SLC36A4 SGMS2 CLEC7A LAIR1 SLAIN2 RGCC TMEM38B SLC7A2 SNED1 ANKRD10 DAB2 FAM49B KCTD20 GCA EFR3A TAF13 RNF149 KIF13A NECAP1 ATP11A PSTPIP2 MSANTD2 MOB1A AGPS DGKG TMX3 PDS5B CSDE1 ACAP2 ESYT1 TXNDC11 ISCU TTC32 OSER1 AIM2 NRG1 EHD4 RNF13 PAPSS2 CSF2 REEP1 PHYH CD70 TMEM50A	down	*
GSE27786_LIN_NEG_VS_MONO_MAC_DN	0.0044286	0.0391022	0.4070179	-0.2732497	-1.446181	169	CXCL3 MRPS18C ADPRH USP12 SLC6A12 MYADM CITED2 NR3C1 WBP4 SPATA21 ERG SLC44A2 PPP1R15B MAP3K8 KLF10 MED11 RIT1 PTPRC AXL TM6SF1 RAP1GDS1 N4BP1 PAFAH1B1 SLC35G6 FMNL2 ASNSD1 CTSS ATXN1L OGFRL1 YWHAZ CYP4A22 RNF146 SLC25A24 ATP6V0D1 NIPAL4 ATG3 MSMO1 PPP2CB EHD1 SPOCK2 PDLIM5 ITPRIPL2 SFT2D1 SLC25A20 AIM2 DAZAP2 BANK1 TRIM36 MED31 CNR2 CLIP1 GPR153 HAS2 ADAMTSL3 FAM160B1 WDR47	down	*
GO_CATALYTIC_ACTIVITY_ACTING_ON_RNA	0.0014547	0.0168131	0.4550599	0.3022660	1.445739	310	DDX12P SLFN13 DROSHA PRIM2 PIF1 METTL1 DGCR8 RAD54B AARS2 POLR3A EXO1 RPAP1 QTRT1 LARS2 NSUN2 TRPT1 EMG1 TARS2 ANG SARS2 POLR3C TRMT61B FBL TRMT2A BRIP1 TRIT1 DDX56 DDX51 HARS2 EXOSC2 DTD1 DIS3L2 TYW1 POLR3K CMTR1 DHX37 DHX33 FEN1 POLR1C METTL3 NOP2 RTCB RNASEH2A DHX34 POLR2H PARS2 MOV10 CNOT2 DHX40 PUS1 AARSD1 USB1 NUDT16 TSEN54 SND1 ELAC2 YARS2 IARS2 PPP1R8 DUS1L POP7 POLR2J FANCM METTL2B NSUN6 DHX8 NOB1 DDX23 POLR2J3 EXOSC5 DUS4L POLR2I POLR3E RNASET2 IGHMBP2 RPP38 DDX55 DUS2 FARSA PRPF18 RRNAD1 PRIM1 DCPS DDX54 POLR3B WDR4 FARSB TARBP1 SNRNP200 POLR1B POLR1A EARS2 DDX52 POP4 APEX1 CDKAL1 DTD2 AZGP1 DDX41 FTSJ3 TFB1M DHX57 POLRMT	up	*
CASP8AP2_TARGET_GENES	0.0046311	0.0403875	0.4070179	0.3059121	1.445682	261	FAM227A C1GALT1 ZNF12 C17orf75 PDCD2L ECE2 FABP6 SAYSD1 TIGD1 ASPHD2 LRRC27 LSM5 NME1 TOP3B RANBP1 TMEM41A BZW2 MT-TY EMG1 TARS2 CBY1 COX19 DNAAF3 TRMT2A ALG3 RBAK KNSTRN HPS4 SSBP1 AAGAB WDR31 AP5Z1 ENPP3 ANKRD26 TMEM79 USP42 MTBP TTC16 CCDC57 CENPP WDR24 CHCHD2 ILF2 THNSL1 SMG5 DNAJA3 PSME2 HIRA COPS7B JMJD4 PDRG1 MTND5P11 IQCH ZNF140 LIMA1 VPS25 MRPS23 SNRPD1 UIMC1 SNAP47 RCC1 RNF31 DDX55 KLHL7 NME1-NME2 ZNF195 BBX BMS1 N6AMT1 TRIP4 ENKUR GTF3C5 VPS9D1 AGBL5 TMEM101 CPOX	up	*
GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN	0.0031532	0.0302940	0.4317077	-0.2743714	-1.444703	170	OLR1 SOWAHC LTA4H SMIM12 LPL STXBP6 ALAS1 MANBA LAMP1 IGSF6 TEX2 EDEM1 SLC36A4 SGMS2 TACC1 NAAA CLEC7A HDC SLAIN2 RGCC TFEC PDE4D TMEM38B SLC7A2 PTPRO MEFV BNIP2 NOSTRIN PLBD1 KCTD20 RAP1GDS1 FAM76B RPS6KA2 ZNF330 NEK7 ATP11A PSTPIP2 CREB1 RALB AGPS CPA3 MTMR2 CSDE1 LGALS3 CRY1 COMMD9 WDR1 SEC63 SEMA4A TIAM1 TXNDC11	down	*
GSE45365_NK_CELL_VS_BCELL_UP	0.0035199	0.0330771	0.4317077	-0.2716278	-1.444672	184	CXCL3 THBD BACH1 FOSL1 PAFAH1B2 SLCO2A1 CBL IER2 EDEM1 PPP1R15B SDE2 PICALM NDEL1 ATP6V1H CSRNP1 ID3 VASP THBS1 CDK9 SOCS5 ATF3 SELP ARC DUSP1 SLC25A32 MOB3A IL6 ARL5B JUNB DNAJA1 IFRD1 CD83 FAM43A YWHAZ TMEM128 AGFG1 FOS FOSB BAZ2B FEM1B ATP6V1A IFNAR1 STX12 RGS2 GEM ICAM1 RNF138 ABL2 WDR1 IER5 HSP90AA1 RND1 BCAT1 ZDHHC5 DOCK10 PAK2 EPB41L4A B3GNT2 LDLR NABP1 HNRNPH1 JDP2 EGR1 RBMXL1 SERPINE1 CHIC2 DUSP6 OSGIN2 S100A8 ZFP36 SPTY2D1 BCL10 WWTR1 SLC23A2 ATF6 SH3BP2	down	*
MIR338_5P	0.0001123	0.0021273	0.5384341	-0.2494328	-1.443861	395	GCOM1 CD55 ZC3H12C RAB3C LDB2 DYRK1A KCNN3 NR3C1 CD9 TSHZ1 TET2 ACER3 TMX4 TBX2 ATP2B1 TRA2B PTPRM MTF1 SDE2 PICALM KLF10 PAQR3 CAV2 CAMTA1 FOXJ3 GATA3 SPTBN1 SPRY2 AMOTL1 CCDC82 PPP6R3 GPA33 DAAM2 KLF11 ZFAND5 TMED5 TADA2B JAM2 TLR4 CXXC4 PPP2R5C PPP2R5A KIAA0408 IKZF5 RABGGTB CNOT6L LIN54 USP25 FMNL2 ID4 HESX1 PDHX IL6 SGK1 COPS2 NEK7 PIKFYVE MITF CUL4A ETS1 CNTN4 TBC1D12 FERMT2 SP3 ACKR3 DDX5 PI4K2B CREB1 COBLL1 LSM1 FSD1L LPCAT2 OGFRL1 DENND4A SPRY4 PELI1 KLF2 CDK17 TSHZ3 DAGLA CHORDC1 AZIN1 ZNF521 LSM6 STRN BAZ2B TEC NAB1 MAP3K2 SOD2 HFM1 TOB1 ANKRD12 KAT2B PDE4B MBNL1 MLANA INO80D CCL20 HACE1 ARAP2 RNF138 FGF2 RLF SEC63 ARIH1 TXNDC11 PTCH1 DDX59 POLR2M MBD5 NPAT JMJD1C FAM126B ABCA8 PAIP2 RORA NAA15 C1orf52 TLK1 WDFY3 EID1 FEZ1 BMI1	down	**
TBK1.DF_UP	0.0007400	0.0100477	0.4772708	-0.2614934	-1.443703	243	IL1A HMOX1 SWAP70 SNX10 LPXN ADCY9 PID1 PLEKHF2 EML1 EOGT TEX2 KIAA0355 HBEGF CSGALNACT2 ANPEP PAQR3 SIRPA RB1 TMEM41B ZFYVE16 BTG3 PPP3CC CYBRD1 DUSP3 AGO3 SAP30BP PLAUR PXDC1 CDIP1 KLF11 DAB2 TMED5 STX3 ITPK1 NFKB1 RIT1 CXCL2 ATF3 UXS1 ARAP3 GCA TP53BP2 DEGS1 NRBF2 BTG1 EMP3 SERTAD2 VAMP3 CREM PKNOX1 PHTF2 SNAP23 PHF10 OSTM1 FERMT2 CD83 TRAK2 TNFRSF10B PELI1 RRAS RIN2 LSM6 DUSP5 MAP3K2 CCDC68 STX12 HSPA2 TNFAIP8 CGRRF1 OPN3 NT5C2 CDC42EP3 LRP12 TMEM184B RNF38 FEZ1 TRIM36 DCUN1D2 RABGEF1 TMEM50A CHIC2 TBPL1 FKBP1B ATP11B ENDOD1	down	*
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP	0.0000823	0.0016390	0.5384341	0.2873050	1.443700	636	HMGA2 ONECUT2 LINC00342 FOXM1 NXPH4 AK4 GPT2 ELOVL6 TFAP2A S100A2 BUB1B NUP107 NEK2 CCNB1 CENPF IGF2BP3 PSPH SLC2A1 NDC80 PRIM2 DEPDC1 SIX4 ZNF138 TTK RACGAP1 KIF14 ANLN ASPM STIL COL7A1 NUF2 AURKB CENPA ECT2 TPX2 TRIB3 FIGNL1 STC2 RBBP8 MCM4 HOXB7 MCM2 HPS3 CCT6A MCM8 MIS18A SRPK1 SHMT2 MOCOS XPOT CCT2 TNC C5orf34 CLDN1 MELK HMMR DLG1 CEP55 SYTL2 GFPT1 SLFN5 DCBLD2 IGF2BP2 TPBG EEF1E1 TOP2A AURKA CBX3 ATR TPR MCM7 RSRC1 RHOBTB3 WDHD1 ZNF146 KIF11 LINC00511 SP140L EGFR POLR3C TOPBP1 CHEK1 ORC6 ACTL6A MAD2L1 RAD51AP1 MRPS30 RBAK MIPOL1 GPX8 FRMD5 NUSAP1 CDK1 DNTTIP1 UCK2 AP3D1 ULBP2 KIF2A PSAT1 PEG10 FEN1 SSX2IP LINC00958 SEMA3A NLN DIAPH3 DNMT1 CEP63 WDR53 C3orf80 PSMA5 TRIO HECTD1 PDRG1 LINC00662 KIF20B ASNS GFM2 TM9SF4 ANAPC1 AHNAK2 TWF1 CCZ1 ENC1 RAD50 SUPT16H CKAP5 CDC20 ZNF616 FAF1 FBXO22 BCL2L1 CXCL1 ZNF780B ZNF160 CKAP2 XRCC4 ANKRD1 HAUS6 DYNC2H1 RCC1 SLC1A5 GAD1 ATAD2 GTPBP10 PMS1 PRR11 STK38 NBPF14 DENR GTPBP2 HK2 OSBPL10 ZWILCH ARHGAP5 COPA ARHGAP11A ZNF700 ZMYND19 NME7 ACP1 TTC39C ZNF131 SMC2 ZNF567 LIF ZNF91 CENPE EIF4G1 ADRM1 PFDN4 DDX52 DNAJC10 CELSR3 TRUB1 PAICS UBE2C PNN FBXO45 KRT80 ENO1 E2F7 DNM1L ZNF367 PPP1R14B CALU BRIX1 IFI16 ERLIN1 SNAP25	up	**
MIR4789_5P	0.0003254	0.0052113	0.4984931	-0.2527433	-1.443104	325	WEE1 AJAP1 GPATCH11 TRHDE SECISBP2L HHEX PTPRE BMPER SEC22C QKI PAFAH1B2 NR3C1 TGFBR3 OTUD4 ASAH1 PPP1R15B MAP3K8 HIPK3 SLAIN2 GATA3 ZMYM6 TCF7L2 TFRC RAB14 GPM6A SCP2 PPM1K ZSWIM6 ITM2B NPAS3 NR1D2 PNRC1 UBE2B PIK3C2A SMAD7 INHBA CMTM6 USP25 UFM1 SPIN1 MOB4 FOXN2 TBC1D12 EEA1 PIK3R1 MBNL2 HERC1 GRB2 FAM43A KBTBD8 RC3H1 DENND4A CASZ1 TPRA1 MORF4L1 SPRY4 TSHZ3 BTBD7 STRN PDS5B BAZ2B VAMP4 SBF2 ATP6V1A CNOT7 CD81 EXOC1 TMEM70 TOB1 MAGOH ADAMTS15 CLCN6 INO80D ARAP2 RNF138 TNFAIP8 ZNF143 CTTNBP2NL EPB41L5 ACAP2 TMOD2 CCR9 PSME4 NUP98 LYSMD3 SCAI FAM126B CAMSAP2 FGFR1 SFPQ WDFY3 PUM1 SPOPL ARFGAP3 DNAJA2 PLAG1 CHP1 CDKN1B DKK3 RB1CC1 SLC38A2 EXOC8 EBF1 XRN2 FAM160B1 WAC PLN TSC22D2 RAD21 DDX21 ARHGEF12 SMARCA5 MEF2D CNTN1 PLCB4 SIRT1 HIVEP1 CAPN7 AKAP13 GP5 PTPRA BMPR1A	down	**
MIR196A_1_3P	0.0002548	0.0042281	0.4984931	-0.2524815	-1.443056	328	WEE1 SEMA6A IL1A SLC12A6 DPYSL2 RCOR1 QKI SLC39A8 MTMR10 STX11 DYRK1A CDC42 TGFBR3 NEDD9 CD9 GNPTAB TET2 FAM49A TMX4 HBEGF ARSB PLXNA2 HIPK3 GLS DACH1 MOB3C TMEM123 TFRC TMEM38B TIPARP EPB41L2 EIF1B PER3 AMOTL1 TLE4 LIN7C PLAUR ADAMTS9 PDE3B UBE2E2 CXXC4 CCND2 WASF3 PTGIS MRVI1 ARL6IP5 VAMP3 RNF149 IL6 PDIK1L SYNPO2 SAR1A PHTF2 PHACTR2 NEK7 ARL6IP6 CNTN4 NXPE3 WTAP SKIL PIK3R1 PI4K2B PCGF5 ZNRF3 RGS13 MEAF6 POGLUT1 CDK17 AZI2 NIPAL4 EPPK1 TSHZ3 DGKG NAA16 ING3 PBRM1 HNRNPA2B1 TCF4 NDUFA5 ZBTB1 KHDRBS1 ATXN1 PPIG LEKR1 CRY1 ACYP2 MICU3	down	**
GSE42724_NAIVE_VS_B1_BCELL_UP	0.0039182	0.0357025	0.4070179	-0.2772128	-1.442522	159	HSPA12B RAB11FIP1 RAPGEF2 PLEKHF2 CITED2 NR3C1 PPP1R15B HDC GLS PPP2R2A ZEB1 CSRNP1 ITPRIP PPM1K CASP1 BST1 SLC7A8 DRAM1 VASP VRK2 IRAK2 FRMD4A UBASH3B KPNA3 MARK3 TFAP2E UBQLN3 INPP5B ELP5 HSPA1B PLK3 JUNB REL GTDC1 ZNRF3 CGGBP1 NAA16 TCF4 IFNAR1 PDE4B ATAD2B PAMR1 SEC63 SETDB2 ATP9B PTCH1 FNBP4 CEPT1	down	*
GO_RESPONSE_TO_PEPTIDE	0.0000584	0.0012276	0.5573322	-0.2476404	-1.442516	412	EREG RAMP3 LPIN2 TEK EDNRB PPARG HHEX CPEB2 IL1B LHCGR CAT ADCY9 ADCY4 PTPRE PID1 KL PCSK9 FYN LPL EGR2 INPP5K CAV1 BAIAP2 VAMP2 PRKAR1A TGFBR3 CD36 ANXA1 MIR146A ATP2B1 BTG2 ANXA5 KLF10 CAV2 ADIPOR1 NR4A1 ADRB2 NFE2L2 NDEL1 CRK ARHGEF2 EPM2AIP1 ATP6V1H ATP6V1B2 FOXC2 IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 KLF4 ROCK1 KLF11 SOCS2 ATP6V1D NFKB1 PDE3B SIK2 VIM ATP6V0D2 TLR4 PIK3C2A GNAI2 TBC1D4 BACE1 GNRH1 BTG1 SLC25A33 PDK4 KANK1 MYO1C ADCY2 AREG PSEN1 SOCS3 APPL1 RAB8B STAT4 NOTCH1 RAB31 USO1 ATP6V0B PIK3R1 GRB2 CREB1 RAB8A PRKACA ATP6V0D1 RHOQ KLF2 CACYBP FOXO3 SRSF6 IRF5 SORT1 STXBP3 SRSF4 FPR2 GNAI1 ATP6V1A IRS2 ATP6V0C	down	**
MIR3529_3P	0.0000787	0.0015800	0.5384341	-0.2423702	-1.442466	461	EPAS1 GPATCH11 SEMA6A SLC12A6 RDX DPYSL2 SMIM12 RCOR1 ZBTB34 GTF2I SLC39A8 ELF2 MEF2A CDC42 NEDD9 CD9 GNPTAB TET2 EOGT CBL HEG1 TMX4 ARHGAP29 CLCF1 NFIX HBEGF FOXA2 RANBP9 KLF10 FOXP1 DACH1 GATA3 TRAF6 ARHGEF2 TMEM38B NBPF12 EPB41L2 GMEB1 EIF1B AMOTL1 TLE4 SGTB KCNMA1 SORBS1 LIN7C PRKD3 ANKRD10 EPM2A ST7L UBE2E2 CCND2 WASF3 SLC25A32 GNAQ RBM44 PDE1C CRIM1 KREMEN1 SIAH1 UFM1 GPBP1 DCP1A FLT1 PDIK1L PHTF2 PLGLB1 PHACTR2 APPL1 PNMA2 KCTD12 DESI2 CELF1 CNTN4 NXPE3 MTMR9 WTAP ELOVL7 SP3 MBNL2 ZNF804A ATL2 FSD1L SLC10A7 ZNRF3 SUCNR1 PREX2 OGFRL1 CELF2 TMEM192 CDK17 YTHDF3 CCDC85A EPPK1 SLC4A5 ING3 CHORDC1 NUP153 PBRM1 HNRNPA2B1 AP1G1 SKIDA1 ATP6V1A KHDRBS1 ATXN1 COL15A1 GNB4 CLASP2 GNA13 ACYP2 N4BP2L2 CCL20 GLTP EPB41L5 PUS10 IER5 PARM1 LRP12 ARIH1 ALDH6A1 TBC1D1 SP100 HAVCR2 ISCU RBMS3 MAP3K4 LYSMD3 CUL3 SCAI ST6GAL2 DNAJB9	down	**
GSE14308_TH2_VS_INDUCED_TREG_UP	0.0049593	0.0425136	0.4070179	-0.2716477	-1.441993	178	SLC12A6 PDLIM2 SECISBP2L DDX6 AKAP7 SPATA1 GALNT18 WBP4 NCEH1 EIF5 PBX3 KLF10 CAV2 SPRY2 SPNS3 PPP6R3 LEPROTL1 TPP1 IRAK2 ARAP3 CLK4 CCSER2 INHBA MYH11 TAF13 MTPN GZF1 BCAR3 NEK7 MAGI2 C20orf194 MAP4K4 JAK1 STX7 ATXN1L DDX5 IDS RBM22 PXK PANK2 SNX9 GPRIN3 ECI2 FOXO3 NAB1 PIK3C3 IRS2	down	*
GO_CELL_JUNCTION_ASSEMBLY	0.0013632	0.0161485	0.4550599	-0.2636272	-1.441990	213	LIMS2 ACVRL1 TEK ACE DLC1 PECAM1 IL1B WNT4 RAPGEF2 RAMP2 CDH5 CAV1 CORO1C CDH13 ESAM CDC42 CD9 EPB41L3 HEG1 RHOA APOD RAP1A ITGA5 JAM3 TNS1 SFRP1 GPBAR1 ROCK2 SNAI1 DUSP3 SORBS1 PTPRO LIMS1 ROCK1 VASP TJP1 THBS1 CLDN5 SMAD7 PEAK1 SRF MYO1C FAM107A PDCD6IP MAP4K4 RAPGEF1 FERMT2 PRKACA PPM1F CD151 GJA4 WNT11 FLNC EPHA3 PARD6A STRN TESK2 CNTNAP1 CLASP2 ACTN2 MACF1	down	*
CIC_TARGET_GENES	0.0007566	0.0102200	0.4772708	0.2961199	1.441671	388	ATP10B MUC13 KIF20A FOXA3 FAM81A FANCI TFAP2A FRK TIMELESS APOLD1 SEMA4B NUDCD3 PHF14 HILPDA KIF14 TTC26 PTTG1 ESPL1 GAPDH AGR2 PLS1 CIB1 GON4L CAND1 XPOT CCT2 UQCC1 KAZALD1 MANSC1 GOLPH3 RPAP1 TP53BP1 KNTC1 WASF1 CLHC1 MSX2 FBF1 CBX3 MYO10 POLD2 MMS22L CDCA5 FANCD2 EMG1 PEX26 ORC6 LRRC61 FBXL19 FADS2 SYMPK EFCAB11 CBX5 ANAPC5 ING4 WDR5B ZMIZ2 FEN1 TNRC18 MTBP SNRPE CENPP RNF44 NET1 TRIM24 NADK2 CNOT2 ARHGAP32 COX7C ITFG2 MAGOHB YARS2 BAZ2A PPHLN1 BRD8 CDC20 ORMDL2 ERBB3 AAAS SIRT4 SRRT KRT8 MRPL24 MCM5 ANKRA2 TDP1 FAM161A EIF3D RTEL1-TNFRSF6B STMN3 LSM4 TCERG1 MCRS1 RN7SL1 GABPB1-AS1 GTF3C2 RTEL1 CDC42BPA TXNL4B MCU ENKUR SNX19 POP4 GLYCTK ZMAT2 TP53 RANBP3 PIGL OAS3 ATF7IP CCDC91 SART3 C12orf10 SETD5 ERLIN1 TEX9 SUMF2 PLAC8 VPS18 WDR55 TMEM259 PEX11A TLN2 ABHD2 TNPO3 MARVELD2 NPM1 PIGS TEFM TRIM59 SEC24C RBM8A PSMD3 STRIP1 INTS9 DHX38 PAN2 KIAA1217 CCDC124 COA6 HNRNPA1 ZNF460 ASB7 HMBS TUFT1 BUB3 HOXA-AS2 WDR93	up	*
MIR4666A_3P	0.0000412	0.0009209	0.5573322	-0.2436984	-1.441118	476	TRIM71 EREG USP12 ZC3H12C EMP2 RDX PTPRE PID1 KL TMEM170B BDNF TMOD3 HEATR5B QKI BMPR2 HMGCR NR3C1 NEDD9 VAPA WBP4 IL23A TMX4 RAP1A PPP1R15B KLF10 PAQR3 KLF6 CAMTA1 PEX5L DACH1 FOXJ3 PPP3CA ADRB2 AKT3 MCL1 ATP6V1H TLE4 FOXO1 SORBS1 PPP6R3 PPM1K ACSL3 KLF4 ITM2B ROCK1 ZFAND5 ARNTL MGAT4A CADM1 C4orf33 ACTR3 BRF2 MBD2 PPP2R5C EXOSC8 GNAQ KIAA0408 PAFAH1B1 CRIM1 RABGGTB CNOT6L TAF13 ZNF426 MTPN USP25 MOB4 CREBRF ID4 PPP2CA CCNY IL6 ASNSD1 SGK1 NEK7 PIKFYVE PDCD6IP PPP6C UTRN PDE5A OSBPL9 MSRB3 RABGAP1 CSTA WTAP FERMT2 FYTTD1 EEA1 HSPA13 PI4K2B MALT1 MSANTD2 HOMER1 ZNF597 PREX2 DENND4A WDR7 KLF2 HIVEP2 SLC4A5 TSHZ3 DAGLA NAA16 ZNF521 STRN CEP76 TRGC1 PIK3C3 TBRG1 ZNF136 TOB1 RIMKLB ETS2 MBNL1 ARPP19 ARAP2 RNF138 FGF2 PDLIM5 SCN7A NT5C2 ARIH1 PTCH1 DDX59 ZDHHC21 SOAT1 KPNA4 MBD5 LYSMD3 ANKRD49 CEPT1 SCAI B3GNT2 TMEM87A ITCH NRG1 NAA15 ZFPM2 EIF4A2 RAB2A ZBTB44 DMXL2 YTHDC1 ABI1 PSIP1 PLAG1 CLIP1 ZNF800 LIN52 CLOCK MAMDC2 OSGIN2 PDCD2 SH3GLB1 SLC38A2 CEP44 TRPM7 UBE2W SGIP1 PLN AKAP12 SERP1 RAD21 PAXBP1 CUL2 ARHGAP44 FNDC3A SMARCA5 NR5A2 ITGA6 NKTR RAB11FIP2 EDIL3 FNIP1	down	***
GSE17974_0H_VS_1H_IN_VITRO_ACT_CD4_TCELL_DN	0.0058775	0.0481608	0.4070179	-0.2714452	-1.441061	174	TUBD1 GPR65 EGR2 IBA57 CCRL2 PRPF38A BCL2A1 IL23A IER2 STARD4 ATP2B1 BTG2 KLF10 ZNF410 NR4A1 EVI2B ADO ID3 NKIRAS1 EVI2A SH2D2A SLC25A32 GZF1 CREM DNAJC27 CRNKL1 CYCS IFRD1 GPR183 KBTBD8 FAM177A1 NAA30 NAB1 PLEKHO2 CCNH GEM MIR155HG SERTAD1 TXNDC15 IER5 TEX10 NLRP3 TOB2 TNFSF9 ZNF165 SLFN11 PUS3 EGR1 ICOS DCUN1D3 YRDC MUL1 CHAC2 BCL10 ANKHD1	down	*
MIR7_1_3P	0.0000209	0.0005207	0.5756103	-0.2391233	-1.440353	548	GPR17 TAL1 CPEB2 DPYSL2 RAB3C KCTD9 LRRFIP1 TMEM170B BDNF CCDC88A DDX6 THAP2 SLC39A8 PRKAR1A TGFBR3 EPB41L3 ABCB1 TMX4 RBM7 SLC7A7 BZW1 PICALM EIF4E TOR1AIP1 PPP3CA PLXNA4 TRAF6 NFE2L2 TMEM41B ZFYVE16 PDE4D PDGFA GPM6A GMEB1 CSRNP1 PER3 HNRNPA3 BNIP2 UHRF1BP1L MVB12B MED6 MPL FBXL3 MGAT4A PDE3B NPAS3 CXCL2 AQP4 PNRC1 EPS15 CCSER2 RNF139 WDR48 N4BP2L1 WFS1 PEAK1 MPC1 PRICKLE2 TM9SF2 CYP26B1 BCLAF1 SMNDC1 ACTR2 SIAH1 C2orf69 TOPORS UFM1 SPIN1 TMPRSS11A SCEL CCNY ELF1 SYNPO2 KIF13A EBF2 NEK7 HCFC2 SEC14L1 SF3B1 OXNAD1 CPEB4 PDE5A CCDC50 FOXN2 VPS26A TBC1D12 SKIL EEA1 MBNL2 ATL2 RC3H1 MFAP4 FSD1L GRIA1 SLC10A7 CDK14 AGFG1 SLC25A24 ADNP2 PELI1 PTP4A1 HIVEP2 YTHDF3 AZIN1 CC2D2B TMX3 KIAA0232 PDS5B ABHD13 CNOT7 MAP3K2 PHF19 PPP3R1 GNB4 HINT3 RIMKLB ACYP2 INO80D RNF138 FGF2 PDLIM5 CEP170 HSP90AA1 LRP12 TMOD2 FBXO30 CREBBP RBMS3 STAM2 THRAP3 MCOLN2 PRKG1 CYTH1 PAIP2 CAMSAP2 FAM13C NAA15 ENDOV WDFY3 EID1 MACROD2 RAB2A MIER3 DMXL2 REEP1 KALRN MB21D2 SLC19A2 DCUN1D3 ITGB1 CMPK1 HP1BP3 CCNT2 CTDSPL2 AQR SRSF11 PRTG FPR3 PIAS2 MTSS1 GPR137B EXOC6 RCSD1 GABPB1 STX16 ARHGEF12 ATP8A1 TMEM220 ARHGAP44 SKAP2 MEF2D RNF111 SETD2 ROBO2 SREK1IP1 EDIL3 FNIP1 PTGS2 IMPACT EML5 YOD1 PJA2 PTPRA DCAF13 SCAF8 IREB2 SENP6 CBLL1	down	***
GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP	0.0058775	0.0481608	0.4070179	-0.2712407	-1.439976	174	LIMS2 OLR1 SECISBP2L HSD17B6 TTC7B HEATR5B MTMR10 SYS1 AGPAT4 CASP9 KCNAB1 CD36 HBEGF CHMP1B HSPB1 PDGFA CWC22 DUSP3 UBTD1 HAUS2 ZADH2 ATG7 ATP6V0D2 UXS1 CRIM1 MMP19 FMNL2 TMOD1 GABARAPL2 SLCO2B1 MITF CPEB4 C11orf58 FYTTD1 FBXL16 SELENBP1 SERPINB6 BTBD6 FOXO3 RIN2 ZFAND6 ZFYVE9 C16orf72 DYNC1LI1 MFSD12 PDLIM5 RAB5A BRWD1 RAD9B LTBP3 ZFAND2A NIPSNAP3A ETFDH TMEM184C USP4 FJX1	down	*
GO_REGULATION_OF_LEUKOCYTE_PROLIFERATION	0.0037578	0.0345858	0.4317077	-0.2705167	-1.439730	177	CD55 HHEX SPN IL1B MNDA FGF10 PRKAR1A CD22 TGFBR2 IL23A ANXA1 CLCF1 ADA TRAF6 WNT3A MAPK8IP1 TFRC IL10 BST1 CLECL1 MPL CDKN1A PTPRC TLR4 IGFBP2 SFTPD HES1 GNRH1 NCKAP1L CD80 IL6 PDE5A RAC2 TYROBP GPR183 RC3H1 PELI1 CD74 VAV3 CD1D CD6 LRRC32 CD86 IRS2 CD81 LGALS3	down	*
MIR888_5P	0.0021492	0.0226898	0.4317077	-0.2657959	-1.438794	205	GCSAML TRHDE PRKG2 RAPGEF2 SEC22C CDC42 OTUD4 TRIB1 ZEB2 NUMB EDEM1 RRAGC LATS2 OLFML2A EIF4E ADRB2 TMEM41B TFEC SETD3 CD58 MYO1B ATL3 CYP20A1 CLK4 CAPZA2 N4BP2L1 SLC25A32 KPNA3 LRRC3 AFF1 CNOT6L RASGEF1B MTPN SERTAD2 MED28 GABARAPL2 KIF13A KCTD12 FOXN2 CREB1 RC3H1 YTHDF3 BTBD7 C16orf72 ADAM10 INO80D ARAP2 RLF ARPC2 MGAT2 EPN2 PIP4K2A MEX3C BRWD1 KPNA4 GLUL NHLRC3 PAK2 PAIP2 FEZ1 ZBTB44 RABGEF1 BHLHE41 RB1CC1 FAR1 IFIT5 SV2B CTR9 RCSD1 S1PR5 RAD21 ATP8A1 MAP3K1 RNGTT USP45	down	*
GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTERNAL_STIMULUS	0.0000324	0.0007500	0.5573322	-0.2420491	-1.438271	501	NLRC4 EREG CD300LF IL17RB SASH1 SWAP70 FCN1 SCIMP SIGLEC16 PGC IL1B FABP4 MNDA THBD FYN LPL LY86 CAV1 CDH13 MYD88 BMPR2 C5AR1 CLEC10A RBM14 S1PR1 FGF10 MARCO IL1RL1 GAS6 OTUD4 PSMD5 LAMP1 SCARF1 RFTN1 IL23A PDE2A CD36 MIR146A PLA2G7 ADAM17 CLEC7A TNIP3 HSPB1 RNF125 IFNK TRAF6 NDEL1 GRN CRTAM UBE2D3 BIRC2 SLC46A2 THBS1 CEBPA STX3 LY96 UBQLN1 CCL3 NFKB1 CADM1 IRAK2 CCL4 TLR4 PTGER3 SFTPD XCL2 FCER1G OXSR1 AKIRIN1 HCK NCKAP1L IL17D CNTF IL6 MUC3A CD160 CTSS APPL1 SEC14L1 PSMA1 ETS1 RAC2 HSPA1B PTGER4 CCR7 DAPK2 PRKCE OSM MALT1 UNC13B PRKACA SUCNR1 PPM1F PLCG2 UBB PELI1 PSMD12 ICAM2 CD74 PIK3AP1 SMPDL3B CCR4 TGFB1 AP1G1 CD1D CD6 FPR2 NLRP6 PIK3C3 CD81 KLRC4-KLRK1 CCR1 ADAM10 CCR6 FGF2 IL18 IL18RAP ARRB2 RTN4 TIAM1 CXCR4 TAB2 RIPK2 UBE2D1 HAVCR2 PSME4 CREBBP ICAM3 TLR10 SIN3A NFKBIA CTSC EDN1 PAK2 KLRK1 AIM2 FGFR1 ITCH LDLR PSMD6 PSMD9 SFPQ IL16 PUM1	down	***
GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN	0.0043157	0.0383960	0.4070179	-0.2791040	-1.438244	144	ARHGAP31 USP12 TMEM170B HMCN2 TMOD3 SAMHD1 KIAA1109 MYD88 ALAS1 SCARF1 COX18 C1orf162 ATP10A CASP1 TDRD7 FAM102B USP25 FMNL2 ELF1 CREM NSMAF OASL CYCS PCGF5 OSM MORC3 ACSL1 PELI1 AZI2 PIK3AP1 SMPDL3B SAV1 GSAP KAT2B MOB3B INO80 XKR8 ALDH1B1 CCR9 PSME4 SNAP29 TLK2 AIM2 EHD4 FEZ2 MIER3 IRF2 AFTPH	down	*
GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN	0.0037578	0.0345858	0.4317077	-0.2701992	-1.438040	177	ACP5 MNDA LPXN CLDND1 SLC15A3 CD1C SLC7A7 IFI30 KLF10 JAM3 GRN TFEC GPM6A CD58 ZMIZ1 FABP5 TBC1D9 AHNAK PXDC1 LY96 ABCC4 COTL1 VIM PAPSS1 CCND2 M6PR PLEK EVI2A TM9SF2 SOCS3 RAB31 CYCS GPR183 COBLL1 IGKV3-20 EHD1 CD1D CBFA2T3 NQO2 THAP11 DECR1 SLC35D2 ELOVL1 SEC61B S100A4 CTSC DOCK10 AIM2 SAMSN1 RORA EHD3 USP48 ACAT1 CD70 CTSH BHLHE41 ING1 ITGB1	down	*
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP	0.0000224	0.0005523	0.5756103	-0.2426234	-1.437830	497	WEE1 RBP4 SWAP70 TEK FABP4 CAT SLC16A4 PTP4A2 DPYSL2 LRRFIP1 FYN CD44 KIAA1109 CITED2 QKI CYB5R3 GTF2I DYRK1A PRKAR1A CD9 CYP4A11 TGFBR2 RHOA ZEB2 HSPE1 NDUFAF1 BZW1 SERINC1 PICALM ANXA5 LITAF GLS FOXJ3 TOR1AIP1 RB1 TMEM123 SRSF2 HNRNPDL SFRP1 ZEB1 SRGN MCL1 ATP6V1B2 PTPN12 EVI2B HMGN1 DUSP3 SCP2 SDCBP ACSL3 LEPROTL1 ROCK1 TMED5 MYO1B SEC24B NR1D2 PTPRC VIM PAPSS1 ID2 EPS15 PIK3C2A ZMPSTE24 PPP2R5C DSTN N4BP1 IL7R MYH11 PAFAH1B1 HLA-DQA1 AFF1 RSRC2 PTH1R ACTR2 SIAH1 TOPORS ETF1 PRKRA COPS2 NEK7 NXF1 VAT1 DESI2 C11orf58 CYCS DNAJA1 SHOC2 IFNGR1 RCAN1 GSTO1 SNX2 SP3 HSPA13 DDX5 SELENBP1 CREB1 RAB8A CRYM MORC3 CDK14 MSMO1 CD74 AZIN1 PPP2CB NUP153 HNRNPA2B1 PHF3 NDUFA5 DPM1 TSC22D1 ATP6V1A GALC APLP2 TOB1 NPTN CLASP2 SERINC3 PPID TSPO AMD1 BMP2K EIF3F RBL2 PDLIM5 NBN SPARCL1 TFPI SRP72 TRAPPC8 HSPA8 MEGF9 HNRNPK CREBBP HNRNPC ARPC5 GRB10 DUT WDFY3 PUM1 RAB2A LYZ HAT1 ARHGEF18 ABI1 HERPUD1 SAP18 HIPK1 ATF2 CX3CR1 MYH10 DYNC1I2 TUBA1A CBR4 SRSF11 HLA-DRB1 UBE2N SCAF11 CAPZA1 SERP1 NMI DLD ATP8A1 SNRPN FNDC3A WWTR1 SH3BGR	down	***
GABRIELY_MIR21_TARGETS	0.0014979	0.0172264	0.4550599	-0.2601486	-1.437259	258	SASH1 OLR1 SOWAHC KLHL8 BMPR2 GTF2I FBXO3 USP47 TGFBR2 UBR3 WWC2 RRAGC B3GNT5 TACC1 LIFR REV3L PAG1 ITSN2 CYP4V2 ZYG11B FBXL5 CYBRD1 AGO4 PER3 LIN7C ZADH2 GAPVD1 MGAT4A TLR4 RECK PIK3C2A CLIP4 GNAQ PRICKLE2 RUFY3 ACTR2 TGFB2 FAM102B FOXN3 SACM1L MTPN SPIN1 PHACTR2 NEK7 UTRN JPH1 RABGAP1 FERMT2 FBXO11 PIK3R1 COBLL1 NAA30 PELI1 USP7 PKD2 BTBD7 PBRM1 DDHD2 ZRANB1 MAP3K2 MEIS1 ATAD2B SESN1 NEK1 SLC31A1 SEC63 OSR1 B3GALNT1 ACAP2 EPHA4 MEGF9 LIMCH1 CUL3 TIMP3 DOCK10 RNF38 PURB ZBTB44 FNBP1 ZNF326 ATP11B ATF2 CLOCK EXOC8 SRSF11 VPS36 TRPM7 WNT5A SCAF11 ARHGEF12 ATP2B4 MAP3K1	down	*
MIR3942_3P	0.0003953	0.0061159	0.4984931	-0.2603073	-1.437046	275	COL25A1 ZC3H12C ATXN3 ADCY9 NUP54 CAPN14 PLEKHF2 CCDC88A CDH13 EML1 BMPR2 P2RY13 RXFP1 TET2 OTUD4 KCNAB1 CD36 MCTP1 SLC36A4 CSGALNACT2 IFNK DACH1 TMEM38B EVI2B CASP1 RUNX1T1 NPR3 SPAG9 IRAK2 LBH PRDM5 CDC40 INO80C PNO1 PIKFYVE ARL6IP6 NXPE3 TMEM251 PTGER2 DENND4A RALB GAS2L3 SLC25A24 AGPS NECAB1 MAPK8 TSHZ3 PKIA TRAPPC10 KLRC2 XYLT1 AZIN1 NIPA2 VAV3 TMX3 PCDH17 ATXN1 GNB4 ANKRD12 RIMKLB N4BP2L2 ADAM10 SMAD2 ITPRIPL2 SCN7A MGAT2 TPT1 TIAM1 CDKN1C ARIH1 ALDH2 UBE2D1 BRWD1 SCPEP1 BCAT1 NALCN RNF38 DLST KIF1B TRAPPC11	down	**
chr17p13	0.0039576	0.0359470	0.4070179	-0.2669529	-1.436612	197	ZMYND15 CXCL16 ASGR1 SCIMP MIR22HG ARHGEF15 GLTPD2 C17orf107 INPP5K SENP3-EIF4A1 VAMP2 CLEC10A SAMD11P1 SCARF1 TLCD2 ZBTB4 EIF4A1 RILP CHRNE NDEL1 CRK CYB5D2 KIF1C SPNS3 P2RX5-TAX1BP3 MED11 TNFSF12 LINC00324 PER1 PAFAH1B1 PIK3R5 SLC35G6 MYO1C SENP3 SLC16A11 HIC1 ELP5 VMO1 RNASEK BCL6B TNFSF13 ADPRM RN7SL608P TMEM107 TIMM22 PITPNA SLC43A2	down	*
GO_CELL_FATE_COMMITMENT	0.0046965	0.0407651	0.4070179	-0.2708292	-1.436341	182	EPAS1 SOSTDC1 SOX18 TAL1 PPARG TBX3 GATA2 SPN WNT4 BMP2 SOX17 FGF10 CDC42 DSCAML1 IL23A RHOA TBX2 FOXA2 WNT2B GATA3 SFRP1 SPRY2 WNT3A ARHGEF2 TCF7L2 MCL1 FOXC2 NODAL TBX4 KLF4 ID2 TBX5 CYP26B1 HES1 RBPJ WNT9A IL6 PSEN1 EBF2 DHH MITF NOTCH1	down	*
CATGTAA_MIR496	0.0058460	0.0479644	0.4070179	-0.2778563	-1.436340	150	SEMA6A BDNF BACH1 LDB2 QKI ELF2 YPEL5 DNAJB14 SEMA6D HSPE1 CAMTA1 DACH1 FBXO8 MTMR6 PPP6R3 ITM2B PAFAH1B1 CREBRF VAMP3 LRRTM2 CPEB4 WTAP KBTBD8 TPP2 YWHAZ ADNP2 HIVEP2 YTHDF3 TSHZ3 EPHA3 KHDRBS1 COL15A1 PPP3R1 STON1 NPTN CLASP2 HACE1 YAF2 PARVA DAZAP2 TRAPPC11 TLK1 MIER3 CHML HMGCS1 UBE2W PAX5 RAD21 DR1 SETD2 ZNF331 SKP1 EMP1 ZCCHC14 CAAP1	down	*
MIKKELSEN_MEF_HCP_WITH_H3K27ME3	0.0017058	0.0189373	0.4550599	0.2991560	1.436205	315	SLC9A3 KIF12 PRLR ONECUT2 B3GALT5 SLC5A5 PTPRT CPLX2 SPOCK1 LAD1 SLC13A3 GALNT6 DOC2A UGT8 SOX2 PTPRN2 JPH3 NPAS1 DNAJC22 SLC5A1 SLC27A2 FGF11 CD164L2 LAMP5 GRIN2A KCNT1 CYP27B1 LSR GRHL3 IGFBPL1 CNNM1 RUNDC3A MARVELD3 FSTL4 DPYS SLC6A20 LAMC2 CBLC CYP24A1 THBS4 TTC22 FNDC5 RSPO4 SNHG11 AP1M2 PROM2 SLC45A1 OXTR GRHL2 IGSF21 NRTN PRRT3 DMGDH SRCIN1 TCF20 SCTR LRRC9 SPAG6 PACSIN1 SLC35F3 GPRIN1 RAB11FIP4 TCTE1 MAST1 IRF6 RBFOX3 KY SALL4 KCNC3 SCN8A SPTBN2 GRIN3B ECEL1 CHD5 ACSL6 NAGS CADM3 KCNB1 NRXN2 SLC6A1 MYO5C CELF4 ODF3B CABP7 BSN CHRNA3 MMP24 STMN3 SKAP1 CDCP1 GAD1 HTRA3 CNTN2 DOK7	up	*
USF_Q6_01	0.0013950	0.0163735	0.4550599	-0.2666287	-1.435677	198	WEE1 SLC31A2 SC5D HMOX1 MCOLN1 SPNS1 RAMP2 BDNF FLVCR2 TET2 LAMP1 HPS5 TRIB1 PICALM EIF4E HNRNPDL LRRN4CL ATP6V1H CSRNP1 TCP11L2 TRIM46 KLF4 SOCS5 UBE2B PER1 GPR157 TLL1 SNN SLC25A33 CREBRF YBX1 SGK1 RAB31 IPO7 EGLN2 DYM CLN3 ADNP2 RHOQ KRTCAP2 HNRNPD EWSR1 HNRNPH3 WBP2 ANKRD12 GNA13 ADAM10 WDR1 VGF DCTN4 SPIB USPL1 RAPGEF3 DUSP7 NR3C2 FAM13B	down	*
GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP	0.0035241	0.0330829	0.4317077	-0.2726140	-1.435450	170	CXCL3 IL1B THBD KBTBD3 SPATA1 IER2 RBM7 ADA BTG2 MAP3K8 ZNF410 ADRB2 FBXO8 FLI1 IL10 CSRNP1 COQ10B CXCL2 CTBS CCL4 JAM2 PNRC1 IGFBP2 DUSP1 UTP23 NCKAP5 MOB4 UBQLN3 SOCS3 ETV3 CELF1 TMPRSS11D OSM MALT1 ZNF597 MEAF6 FOS ATG3 FAM204A ING3 BCAS2 IGLON5 EWSR1 ORM2 PDE4B ALDH1B1 SLC25A20 NLRP3 UBE2D1 LRRC4B TTC19 TNFSF9 AIM2 MT2A ZBTB44 ZNF800 TREM2 ZFP36 MT1E CD69 ESCO1 IRF1 ZNF347 DR1 NFIL3 KLHL9 CFLAR PTGS2 CCNC	down	*
GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN	0.0053882	0.0451774	0.4070179	-0.2703916	-1.435326	178	ACP5 TSPAN4 OSBPL1A FABP4 FBP1 TIE1 LIPA LY86 QKI CLEC10A IDI1 MEF2A FGR GGA2 ASAH1 ENTPD1 GM2A IFI30 LAIR1 HNRNPDL GRN CES1 APOC1 EXOSC9 CFD PTPRO TNFSF12 CEBPA CTSD PDE3B FKBP15 KLRB1 SLCO2B1 VAT1 CTSZ DNASE2 KLHL18 CLN3 CD151 TIMP2 BCAS2 DDHD2 CD86 GALC DOK2 NQO2 DECR1 VPS39 BMP2K IQSEC1 PIP4K2A CDKN1C TBC1D1 IFFO1 SREBF2 ACADM	down	*
MIR106B_5P	0.0000173	0.0004468	0.5756103	-0.2357923	-1.435193	586	WEE1 RAB11FIP1 EREG TMEM100 ABHD5 FGD5 SOWAHC ZC3H12C DPYSL2 ST6GALNAC3 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 C3orf70 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 CRK ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 MSR1 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK SGTB BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 VASP ZADH2 STK17B FBXL3 ATG7 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 CLIP4 PAFAH1B1 KPNA3 NCKAP5 TANC1 CNOT6L CNRIP1 VCPKMT ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 MAPK8 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 TGFB1I1 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 TAGAP KAT2B PHLPP2 PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 UBE2D1 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	***
GSE15930_STIM_VS_STIM_AND_IL12_48H_CD8_T_CELL_DN	0.0043384	0.0385183	0.4070179	-0.2697587	-1.434731	184	ACE GPR65 CLDND1 BDNF TMOD3 ST3GAL6 NEDD4L MYD88 IL1RL1 PFDN1 GNGT2 AHRR MAP3K8 SLC7A11 SERPINB9 ADRB2 IL18R1 CD93 TMEM41B RHOB FABP5 STAT5A KLF7 CDS2 SELP HOPX PRF1 DSTN SH2D2A IL7R RBPJ IL6 SOCS3 IL2RB JUN DDX17 ST6GALNAC4 STX7 ACSL1 SPOP EHD1 NAB1 PIM1 CSDE1 LGALS3 ACYP2 GEM ADORA2A GTF2F2 KIT CCND3 MT2A GIMAP4 GPN2 HERPUD1	down	*
UDAYAKUMAR_MED1_TARGETS_DN	0.0016735	0.0186765	0.4550599	-0.2627351	-1.434324	211	HSPB7 HMOX1 ADCY9 FOLR1 THAP9-AS1 NEDD4L CITED2 DYRK1A PPM1D TRIB1 SPCS3 PDE2A TXNIP ADAM17 LIFR PPP3CA KANK2 RHOB EFCAB14 HNRNPA3 KLF4 PXDC1 MAP1LC3B DENND3 GRK5 SPAG9 TMBIM1 CDKN1A NR1D2 ATF3 AXL ID2 ARL4A VCPKMT BTG1 TRGC2 RYBP CREM MN1 JUNB RCAN1 IFRD1 ACKR3 HERC1 EHD1 PEA15 DUSP5 PIM1 HBP1 MEIS1 GABARAPL1 ACYP2 RGS2 CLEC2B ETS2 INTS6 TFPI CDKN1C TIMP3 PTEN TMEM87A DNAJB9 TNFSF9 FAM13B RNF13	down	*
THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN	0.0021968	0.0230596	0.4317077	-0.2643565	-1.433911	203	SLC31A2 HHEX LRRFIP1 CITED2 GTF2I PRKAR1A ENTPD1 ABCG1 SLC19A1 TCAP FLI1 FOXO1 ROCK1 PDE3B VIM ZMPSTE24 GCA GNAQ GNAI2 CALM2 ARHGDIB NCOA1 STK24 PRCP SLC25A3 S1PR4 SNAP23 SEC14L1 CSTA JAK1 DAPK2 IDS RPS6KA1 CELF2 PLCG2 CALM1 NUP153 TGFB1 SRSF4 CBFA2T3 TOB1 RGS2 ADAM10 ME2 GTF2B RBL2 SELPLG FKBP1A CREBBP ICAM3 CYTH1 ANXA11 IQGAP1 FEZ2 EIF4G2 KLC1 TBPL1 CAPZB	down	*
GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP	0.0036301	0.0337866	0.4317077	-0.2722382	-1.433471	170	LPIN2 OLR1 GPR15 GPR65 HCAR2 P2RY13 ADAM17 CSRP1 HDC ANPEP GLS PPP2R2A MOB3C CRTAM TXN BIRC2 ATF3 IRAK2 MBD2 PAFAH1B1 PI4K2A SNN DDHD1 SOCS3 JUNB ENPP4 GTDC1 BLOC1S6 MORF4L1 PIK3AP1 GSAP TEX14 FPR2 TSC22D1 NAB1 UTP3 STX12 RGS2 PDE4B ICAM1 XKR8 TRAF1 TMEM184B MAFK EDN1 TLK2 SPATA5L1 FEZ2 DNAJA2 SPSB1 CHIC2 CLEC4E TRMT1L ZYX ZFP36	down	*
GO_REGULATION_OF_SYSTEM_PROCESS	0.0000738	0.0014981	0.5384341	-0.2444530	-1.433002	424	TNR RAB11FIP1 EPAS1 HSPB7 TMEM100 SCN4A ACE EDNRB IL1B EMP2 FIG4 TRPC3 SHANK3 HCAR2 INPP5K CAV1 BAIAP2 CALCRL ADRA1D BMPR2 TBXA2R FXYD2 FGF10 MEF2A GAS6 SCN5A RHOA TBX2 ATP2B1 HBEGF ADA CACNA2D2 LMNA KCNK3 PBX3 GLS ADRB1 DES PPP3CA ADRB2 PDE4D SGCA SETD3 TMEM38B CNN1 IL10 FABP5 ROCK2 TNNC1 FOXO1 KCNMA1 NPNT PTPRO TACR2 PTAFR KLF4 ROCK1 GAA CDK9 CCL3 SSH1 PER2 ITGAX PTGER3 WASF3 SMAD7 ZMPSTE24 INHBA FXYD7 GNAI2 CALM2 MIR17HG TGFB2 MTPN SRF KCNA5 SLC8A1 SCN4B SGK1 RAB8B UTRN NOTCH1 HRH1 ADRA1A PDE5A GSTO1 PTGER2 NPR1 UNC13B PRKACA HOMER1 CST7 CELF2 LMCD1 CALM1 FOXO3 TSHZ3	down	**
GO_SEXUAL_REPRODUCTION	0.0003217	0.0051621	0.4984931	0.2878725	1.432920	538	TSPAN8 SYT8 TRIP13 TP63 SPATA24 SPATA25 MYCBPAP FOXA3 PPP1R1B RUVBL1 PMFBP1 SPINK13 CCNB1 WFDC2 DPY19L2P1 CLGN GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 NOX5 SPINK1 CIB1 TDRKH MCM8 SRPK1 CCT2 RSPH1 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A CCT5 AURKA REC8 ODF2 SYCP2 POC1A IL12B DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 OAZ3 CGB7 HSF2BP MST1R OXTR BRIP1 GNPDA1 SPAG8 PTGDR2 CCDC136 ALDOA MEA1 ASF1B LRGUK CDK1 MERTK PICK1 CCT3 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 MTOR CTSV MNS1 ADAM28 IQCG MORN2 UBE2Q1 PCSK4 GAS2 TSSK3 SPAG1 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 THRB TYRO3 CCT7 NR6A1 KDM3A PTN MEI1 ROPN1B AAAS BCL2L1 CATSPER2 BAD DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 PKDREJ GGT5 ETV6 PHC2 PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2	up	**
GO_LYMPHOCYTE_ACTIVATION	0.0000236	0.0005760	0.5756103	-0.2363248	-1.432224	573	SIRPB1 SWAP70 CD55 HHEX GAPT SPN IL1B MNDA WNT4 LYL1 FYN CD44 CAV1 FGF10 PRKAR1A CDC42 CD1C GAS6 LAMP1 CD22 SLC11A1 TGFBR2 IL23A CD8A FGR RHOA ANXA1 CLCF1 FBXO7 CD5 ADA ADAM17 CLEC7A MAP3K8 FOXP1 KLF6 HLX PAG1 MS4A1 LCP1 IFNK GATA3 PPP3CA SIRPA IL18R1 TRAF6 SFRP1 WNT3A ZEB1 SPI1 MAPK8IP1 TFRC ZMIZ1 IL10 NRARP DUSP3 BST1 SLC46A2 FUT7 CLECL1 SOCS5 MPL FAM49B CDKN1A PTPRC AXL ID2 TLR4 IGFBP2 SFTPD PRF1 FCER1G SMAD7 INHBA IL7R CYP26B1 HES1 MIR17HG GNRH1 SRF NCKAP1L CD8B RBPJ CD80 IL6 PKNOX1 CD160 PSEN1 PDE5A RAC2 TYROBP PTGER4 CCR7 SP3 PIK3R1 CD83 GRB2 GPR183 MALT1 RC3H1 DOCK8 AP3B1 CD7 TBX21 ZNF683 TIGIT PLCG2 CD151 PELI1 AZI2 TNFSF13 RUNX3 TREX1 CD74 CR1 TGFB1 VAV3 AP1G1 CD1D ZBTB1 JMJD6 CD6 LRRC32 CD86 IRS2 PDCD1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 BAG6 MFNG GPR18 UNC13D CCR6 ICAM1 IL18 LAT FKBP1A NBN SEMA4A RIPK2 NLRP3 CCR9 HAVCR2 CD19 ADORA2A KIT DOCK10 CD3G PAK2 KLRK1 DNAJB9 TNFSF9 SAMSN1 RORA CCND3	down	***
DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP	0.0012266	0.0148877	0.4550599	-0.2622289	-1.432164	228	SC5D GATA2 PTPRE CD44 CAV1 YPEL5 HMGCR KCNN3 NR3C1 CD9 FAM49A HEG1 TMX4 ARHGAP29 CSRP1 CAV2 TCF7L2 CD58 RHOB CYBRD1 FABP5 TBC1D9 ARRB1 FOXO1 KLF4 ITM2B ID3 OSTF1 THBS1 MAP1LC3B BCHE SOCS2 CADM1 ID2 CCND2 M6PR DUSP1 ELK3 INHBA HES1 MAFF ADD1 SERTAD2 CREM SGK1 PHACTR2 AQP3 JUN SH3BP5 MN1 MAP4K4 JAK1 ACKR3 CAP1 FGFR4 PELI1 MME EPHA3 VAV3 PEA15 TGIF1 TGFB1I1 IRS2 PCDH17 LTBP1 ADAM10 TCF7L1 PCCA TXNDC15 CXCR4 CUL3 CTSC MMD THEMIS2 NRP2 HEBP1 CREG1	down	*
GSE22886_NAIVE_TCELL_VS_NKCELL_DN	0.0032437	0.0310004	0.4317077	-0.2693026	-1.431877	175	RAB11FIP1 PTPRE GFOD1 LDB2 NEDD9 LAMP1 FAM49A RFTN1 HEG1 TACC1 MAP3K8 IL18R1 ZFYVE16 ATP10A GMEB1 ZCCHC24 DAB2 SSH1 PTPRC TM6SF1 SH2D2A HTT CRIM1 PI4K2A ADCY2 NOTCH1 STX7 FRYL UVRAG RNF146 PLCG2 RHOQ UBB CDK17 TCF4 GOLGA8H ATP6V1A CLASP2 PLEKHO2 IST1 HELZ ARAP2 INTS6 IL18RAP CEBPD SLC25A20 ARIH1 MEX3C PSME4 TMEM87A LYST SNAP29 ITCH FAM13B FEZ2 SETX UBR2 AOAH SH3GLB1 ATP1B1 WDR41 UBE2W S1PR5 ARHGEF12 UEVLD DUSP22 CFLAR JARID2 LARP7 IVNS1ABP GSN	down	*
GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN	0.0032437	0.0310004	0.4317077	-0.2692933	-1.431827	175	DENND5A RAPGEF2 FYN TMOD3 GTF2I CDC42EP2 INPP5A RFTN1 GGA2 BZW1 EIF4E LAMTOR3 ZFYVE16 ATP10A PTPN12 EIF1B COQ10B THBS1 TMED5 VRK2 GRK5 SOCS5 SNIP1 DSE SH2D2A PEF1 RSRC2 PROCR TULP2 SERPINB8 MITF MN1 PLK3 DUOX1 GPRC5A ZNF350 CD164 NOP10 NAPG AZIN1 PPP2CB EHD1 JMJD6 PLSCR4 PHF11 KYNU MAGOH PLEKHO2 HAUS3 NBN MGAT2 DNAJB9 ZNF165 DOCK4 MT2A MAN1C1 PPP1CB DKK3 HMGCS1 CENPC MYH10 SLC38A2 DNAJB4 FPR3 ACTR1A RAD21 FNDC3A PDPN BBIP1 JARID2 IRF4 MSC CASP3 EBI3	down	*
GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP	0.0026966	0.0267814	0.4317077	-0.2691804	-1.431369	176	ST8SIA6 ADPRH HVCN1 DCSTAMP LMO2 CCDC88A S1PR1 CD22 EDEM1 CD36 PLA2G7 ASAP1 MTF1 CLEC7A ZBTB21 ANPEP TTYH2 SLC7A11 CLN5 ADRB2 PTGIR BST1 KLF4 KLF9 CEBPA ITPK1 PMM1 COTL1 VIM SELL ATP6V0D2 DSTN PROCR FRY BCAR3 DDHD1 CPEB4 CTSZ ATP6V0B SNX9 ATP6V0D1 MIA3 COL15A1 BRI3 PLEKHO2 MFSD12 GLTP ALDH1B1 DCTN4 CDKN1C ALDH2	down	*
GO_RESPONSE_TO_INSULIN	0.0010078	0.0128084	0.4550599	-0.2620034	-1.430803	219	LPIN2 PPARG CPEB2 IL1B CAT PTPRE PID1 KL PCSK9 LPL EGR2 INPP5K BAIAP2 VAMP2 ATP2B1 CAV2 ADIPOR1 NDEL1 EPM2AIP1 ATP6V1H ATP6V1B2 FOXC2 IL10 RAB12 FOXO1 SRSF5 SORBS1 ATP6V1D PDE3B SIK2 ATP6V0D2 PIK3C2A GNAI2 TBC1D4 SLC25A33 PDK4 KANK1 MYO1C SOCS3 APPL1 RAB8B RAB31 USO1 ATP6V0B PIK3R1 GRB2 RAB8A ATP6V0D1 RHOQ FOXO3 SRSF6 SORT1 STXBP3 SRSF4 ATP6V1A IRS2 ATP6V0C CRY1 KAT2B	down	*
GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN	0.0016600	0.0185815	0.4550599	-0.2679606	-1.430575	185	NLRC4 ACP5 CXCL16 KLF13 GAPT PTP4A2 GIMAP8 ENG SH2D3C CTDSP1 FUCA1 CBL FRAT1 TACC1 IFI30 GRN ARRB1 MPEG1 LAPTM5 COTL1 EVI2A PIK3R5 GNAI2 CALM2 MOB3A STK24 HCK EMP3 ARL6IP5 HECA RAB31 DDX17 RHOG RPS6KA1 CAP1 RASSF2 RUNX3 IRF5 TFEB DOK2 THAP11 PLEKHO2 MR1 SLC43A2 CALHM2 ELOVL1 CXCR4	down	*
MIR548AH_5P	0.0007094	0.0097354	0.4772708	-0.2505469	-1.430241	306	EPAS1 SLC31A2 TDRD6 FGD5 CLEC12A RCOR1 CITED2 EML1 SLC39A8 MTMR10 RXFP1 C3orf70 OTUD4 ACER3 TXNIP KCNAB1 CD36 SGMS2 PPP1R15B MTF1 BZW1 BTG2 MS4A14 FZD4 LITAF REV3L PEX5L SLAIN2 FOXJ3 PPP3CA BTG3 FBXL5 TBC1D9 SCP2 REST PRKD3 VASP FBXL3 SPAG9 AQP4 PIK3C2A ELK3 UTP23 PRICKLE2 UBASH3B MARK3 FAM76B ADD1 ACTR2 BTG1 PDK4 TMEM9B MYLIP DNAJC27 PHTF2 DDHD1 DCTN6 PLEKHA3 RAB8B NDNF C2CD2 PDE5A HERC1 FSD1L CXCL5 TMEM128 AGFG1 PKD2 STRN NDUFA5 ZFYVE9 GNAI1 MAP3K2 NBEAL1 ADAM10 PHLPP2 BMP2K PDLIM5 MIER1 LRP12 EPHA4 HSPA8 UBE2D1 ZDHHC21 SSH2 NPAT FNBP4 BCAT1 RNF38 SCAI TMCC3 DOCK4 EIF4A2 ANO6 TRIM36 MED17 ZFYVE26 ZNF800 CLOCK PRKCH ITGB1 YWHAB PTDSS1 CEP44 LAMP3 GPR137B PDE7B TRIM13 RAD21 TES EP300 TYRP1 SMARCA5 B3GALNT2 ZFYVE21 SETD2	down	**
GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP	0.0029050	0.0283995	0.4317077	-0.2710693	-1.430213	171	SIRPB1 ACP5 FCN1 LTA4H CYP27A1 LIPA FIG4 CCRL2 VAMP2 FUCA1 FGR EIF4A1 CD37 DUSP3 ADO PXDC1 FUT7 ITGAX HLA-DQA1 MAPRE2 PI4K2A SIAH1 GLB1 RPS6KA2 PRCP BCAR3 CYB5R1 VAT1 STX7 EEA1 CD83 STX5 SERPINB6 RASSF2 CLN3 PLCG2 CD151 IRF5 PIM1 FCGRT PCCA GSTM5 ALDH1B1 LMOD1 SEC61B IFFO1 TMEM184B KCNJ9 SREBF2 ATF4 SMPD1 ETFDH ATP6V0A1	down	*
MIR12136	0.0000009	0.0000330	0.6594444	-0.2294187	-1.430188	839	RTKN2 CXCL3 EREG COL25A1 TAL1 USP12 SECISBP2L RBMS2 GATA2 ZC3H12C CPEB2 DPYSL2 PTPRE RUNDC3B CCDC88A CLEC12B BAG4 LDB2 CAV1 CORO1C NEDD4L INPP5A PAFAH1B2 ARL8B MEF2A KCNN3 VAPA C3orf70 TSHZ1 PSMD5 EOGT ZBTB2 MOB1B PPM1D RCHY1 ABCB1 ACER3 PDCL ZEB2 UBR3 SGMS2 HECW2 ADAM17 LATS2 MTF1 ABCG2 ECHDC1 ZNF503 FOXP1 HIPK3 KLF6 PAG1 SLC7A11 PEX5L PPP2R2A SLAIN2 PPP3CA SRSF2 NFE2L2 SPTBN1 HNRNPU UBE2D3 TXN RAB14 GPM6A SLC7A2 KDSR CPED1 CYBRD1 AGO4 NRARP SGTB BNIP2 ZNF423 PRKD3 ID3 KLF9 ANKRD10 TJP1 STK17B SCAF4 UBQLN1 SSH1 MGAT4A VIM ARHGEF26 ID2 USP44 ACTR3 UBE2B ELMSAN1 MBD2 CUL5 GNAQ TM9SF2 SMNDC1 GNAI2 FAM76B SEC31A TLL1 EFR3A CNOT6L ZDHHC20 FAM102B LIN54 SRF USP25 SERTAD2 RBM39 KANK1 PKIG MOB4 MYLIP RBPJ PPIL4 CREBRF AREG RYBP SAR1A PHTF2 PHACTR2 NEK7 APPL1 PPP6C SLC9B1 NXF1 ARL5B NOTCH1 HMBOX1 KCTD12 ETS1 DESI2 BMP3 TMPRSS11D DUSP8 SKIL EEA1 TTC14 SP3 MBNL2 GPR183 CREB1 LUZP2 ATL2 RC3H1 ATP13A3 HOMER1 AP3B1 TRAK2 OGFRL1 RNF146 SNX9 PTP4A1 YTHDF3 SLC35F1 BTBD7 SAV1 HNRNPA2B1 TMX3 STRN CCP110 ABHD13 YTHDF2 SKIDA1 MCUR1 MAP3K2 RELL1 ATXN1 HNRNPH3 ANKRD13A HFM1 ANKRD12 NPTN CRY1 GNA13 MICU3 KAT2B PDE4B ARPP19 SMAD2 INO80D RNF2 RNF138 PDLIM5 EPB41L5 SCN7A B3GALNT1 ACAP2 CXCR4 CYB5R4 SEC61B ZBTB25 TOB2 UBE2D1 USH2A SSH2 SRSF10 KPNA4 RBMS3 ULK2 TTC32 STAM2 LIMCH1 BCAT1 SIN3A TTC28 SCAI PAK2 FNIP2 SKI TMEM87A FAM126B PRKG1 MMD C21orf91 RORA DOCK4 GRB10 GSPT1 DUT EVI5 MIER3 TRIM36 CACNA2D3 ZBTB44 ELP4 ZNF326 ACVR1C UBR2 SPPL2A NR4A2 HIPK1 SLC19A2 MAPK1 CLOCK MZT1 OSGIN2 ITGB1 SH3GLB1 RB1CC1 SLC38A2 KMT2E EFNB2 PIGK SNW1 CCNT2 DNAJB4 CTDSPL2 EBF1 PPIP5K2 PRTG PPFIA1 TRPM7 UBE2W SPTY2D1 FAM160B1 SGIP1 LDB3 GPR137B ZNF362 BCL10 RAD21 STX16 PCDH15 IRF1 PYROXD1 RCBTB2 FNDC3A KLHDC1 WWTR1 WDR26 SETD2 RC3H2	down	***
GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP	0.0042908	0.0381884	0.4070179	-0.2686594	-1.429845	177	DNAH17 ACP5 PDLIM2 USP12 KLF13 LY86 CALCRL BCL2A1 IER2 AVPI1 CD36 RRAGC AKT3 ZYG11B RNFT1 PXDC1 COQ10B MAP1LC3B KLF7 FBXL3 CDS2 DUSP11 RECK PINK1 N4BP2L1 CNRIP1 PROCR S1PR4 SOCS3 HECA RAB31 CTSZ JUNB ARHGEF10 STX5 TMEM167B IP6K1 AZI2 GIMAP1 BAZ2B IFNAR1 SLC35D2 PDLIM5 SEC63 ACAP2 SETD4 ULK2 FNBP4 SNAP29 CYTH1	down	*
GSE24574_BCL6_HIGH_TFH_VS_TCONV_CD4_TCELL_UP	0.0040608	0.0366017	0.4070179	-0.2745769	-1.429661	161	RBP4 AJAP1 EPAS1 CXCL3 ARHGEF15 INPP5A STX11 MARCO NR3C1 CD9 PDE4C CD5 SERPINB9 NR4A1 SLC5A2 SYNPO DUSP3 C14orf132 ADO GCHFR ID3 CCL3 CXCL2 RAP1GDS1 GNAQ OXSR1 HES1 PLCD1 GNRH1 NINJ1 LRRTM2 SH3BP5 BMP3 GSTO1 MALT1 TNFRSF10B PTP4A1 PSMD12 RUNX3 TGFB1 CD6 DUSP5	down	*
MIR95_5P	0.0000279	0.0006610	0.5756103	-0.2343137	-1.429468	569	SLC24A4 SEMA6A CD300LF SLC12A6 TBX3 ZC3H12C CPEB2 WNT4 P2RY1 GPR65 KCTD9 TMEM170B BDNF KLHL8 GFOD1 CALCRL QKI GPCPD1 INPP5A PAFAH1B2 IDI1 CIR1 NR3C1 MOB1B TMX4 EIF4A1 NCEH1 CARD16 ADAM17 LATS2 SDE2 ZBTB21 CAV2 FOXJ3 PPP3CA SPTBN1 TFEC ZEB1 SRGN ARHGEF2 PDE4D HERC3 MYCT1 GPM6A FBXL5 SNAI1 SGTB PTPRO SLC12A4 COQ10B REST ADAMTS9 TMED5 SOCS5 ZNF24 NPR3 CXCL2 C9orf72 PTGER3 UBE2B CCSER2 RNF139 RPF1 MBD2 TBX5 CLIP4 GNAQ NUS1 TP53BP2 MAFF RSRC2 TGFB2 HEXB SRF PPIL4 RYBP PDIK1L VPS37A SGK1 MAGI2 PIKFYVE PDCD6IP PPP6C SEC14L1 HECA NOTCH1 RAC2 ATP6V0B CCDC50 PLK3 JUNB FOXN2 EPC1 DHX15 SKIL MPZL3 SP3 PABPC4 PSTPIP2 PRKCE IDS ATL2 MORC3 FSD1L NOL7 WDR7 OCIAD1 BLOC1S6 GPRIN3 RRN3 BCL6B CDK17 CD164 YTHDF3 USP7 EHD2 PPP2CB SAV1 AKIRIN2 TMX3 ISM1 DCAF5 ABHD13 ATP6V1A FSIP1 PCDH17 ATXN1 C8orf37 KCNA3 TAGAP ANKRD12 STX12 CLASP2 FAM180A SMAD2 INO80D ICAM1 CCDC69 CXCR4 DIXDC1 TXNDC11 ZDHHC21 PARVA MBD5 COMMD8 CUL3 RASSF8 TTC28 MAFK CTSC RNF38	down	***
GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP	0.0053714	0.0451254	0.4070179	-0.2694862	-1.429219	182	IL1B LRRFIP1 EGR2 GTF2E2 S1PR1 BCL2A1 HPS5 ATP2B1 LTBP4 HBEGF ADAM17 PAQR3 EIF4E IL18R1 NFE2L2 SRGN MAP2K3 PRKD3 SPAG9 PER2 NFKB1 ATF3 CDS2 CCND2 CALM2 PPP2CA PNO1 CD48 GABPA CYCS RHOG TMEM251 IPO7 GLIPR1 SP3 NOL7 ACSL1 HIVEP2 PEA15 DUSP5 GNAI1 ATP6V1A NAB1 GNG5 CD81 UTP3 ZNF267 GEM ANKLE2 WDR1 CEP170 CDC42EP3 UBE2D1 IPO5 SREBF2 COPS8 PSMD9 FEZ2 EIF4G2 SNRPG	down	*
GO_ENDOCYTIC_VESICLE	0.0015160	0.0173744	0.4550599	-0.2613028	-1.429145	242	FFAR4 RAB11FIP1 MCOLN1 SCIMP HVCN1 WNT4 RAPGEF2 CAV1 HEATR5B CDC42EP2 CDC42 MARCO NCF2 CD9 LAMP1 SLC11A1 SCARF1 CD36 HBEGF RILP RAP1A PICALM FZD4 WNT3A RAB14 MSR1 RAB12 MPEG1 NOSTRIN VIM ATP6V0D2 SFTPD EPS15 HLA-DQA1 ANXA3 LMBRD1 TBC1D5 SNX3 MYO1C VAMP3 INPP5B SNAP23 APPL1 RAB8B RAB31 SFTPB RAC2 ATP6V0B RAPGEF1 STX7 RAB8A GRIA1 UNC13B UVRAG ATP6V0D1 UBB CD74 STXBP3 SFTPC PIK3C3 ATP6V0C STX12 SYT11 EPN2 ARRB2 RAB5A HSP90AA1 PTCH1	down	*
HALLMARK_IL2_STAT5_SIGNALING	0.0054277	0.0453599	0.4070179	-0.2692602	-1.428020	182	SWAP70 DENND5A GLIPR2 LRRC8C GPR65 BMP2 CD44 BMPR2 SLC39A8 IL1RL1 ABCB1 TNFRSF8 MAP3K8 KLF6 IL18R1 RHOB IL10 AHNAK SOCS2 ITIH5 SELL SELP HOPX SHE CCND2 ARL4A MAFF PTH1R MYO1C PHTF2 IL2RB CD48 CTSZ IFNGR1 GSTO1 CD83 IRF8 PTGER2 SERPINB6 TNFRSF9 CST7 SNX9 SPRY4 CCR4 CD86 PIM1 CD81 GABARAPL1 SYT11 TIAM1 CDKN1C ITGAE PTCH1 TRAF1 FAM126B RORA CCND3 RNH1 CSF2 PRKCH ICOS CD79B SNX14 NFIL3 ITGA6 IRF4 TTC39B CASP3 NFKBIZ GALM EMP1 PNP ADAM19 TNFRSF1B F2RL2 IL10RA CAPG	down	*
MULLIGHAN_MLL_SIGNATURE_1_UP	0.0004025	0.0061948	0.4984931	-0.2486362	-1.427816	334	SIRPB1 PECAM1 CLEC3B SNX10 CAT ADCY9 IL1RN FUCA1 LAMP1 PILRA DPEP2 SPG21 PBX3 LCP1 DACH1 TOR1AIP1 SIRPA ADRB2 GRN HNRNPU SPI1 ADARB1 EVI2B CASP1 PTAFR FUT7 MVB12B CEBPA TPP1 LAPTM5 PER2 PMM1 ITGAX RRP8 ID2 CD302 RECK M6PR CD300C EVI2A ACTR2 TDRD7 HEXB RAB6A SRF ARL6IP5 PSEN1 SERPINB8 RAC2 MTMR9 CSTA RCAN1 IRF8 SDHD GRB2 MALT1 SNX1 RPS6KA1 TNFRSF10B RASSF2 CLN3 CALM1 TNFSF13 RBKS ATG3 TREX1 NKG7 TRAPPC10 FXYD6 TFEB MEIS1 CCR1 THAP11 PPID MR1 MBNL1 RXRA PITPNA SELPLG ARPC2 IQSEC1 CDC42EP3 CXCR4 NLRP3 SCPEP1 S100A4 COMMD8 JMJD1C DUSP7 LYST ABCA8 CCND3	down	**
MARTENS_BOUND_BY_PML_RARA_FUSION	0.0000687	0.0014058	0.5384341	-0.2458136	-1.427053	406	AJAP1 RAB11FIP1 ACP5 PEBP4 HMOX1 FCN1 KLF13 SPN PGC SIK1 LYL1 LMO2 GFOD1 C5AR1 NUDT9 FRAT1 FGR LINC00311 UBL3 LATS2 SDE2 NMUR1 SIRPA SPTBN1 TMEM41B ARHGEF2 SPI1 CD58 ZMIZ1 MAP2K3 ARRB1 ST3GAL2 VASP DENND3 CDK9 GRK5 CTSD LAPTM5 COTL1 P2RY2 CDS2 ID2 MIR24-2 ALOX5AP PLEK INHBA SLC6A6 RSL24D1 UBASH3B MRVI1 RSRC2 KREMEN1 STK24 HCK NINJ1 RPS6KA2 PKIG WNT9A RNF149 PGD MAML2 RWDD1 RAB31 RAC2 MN1 TYROBP RPL9 AK1 RAPGEF1 DAPK2 IRF8 DDX5 RPS6KA1 NUDT15 TNFRSF10B TAGLN2 ZNF683 TPRA1 CELF2 MCAM ACSL1 PLCG2 KLF2 CD164 HIVEP2 MBP RUNX3 SLC7A5P1 FOSB PIK3AP1 FXYD6 TIMP2 DOK3 SERPINB1 HECW1 YTHDF2 MIR23A DUSP5 GALC ATP6V0C APLP2 FCGRT	down	**
FARMER_BREAST_CANCER_APOCRINE_VS_BASAL	0.0028537	0.0280259	0.4317077	0.3004336	1.427025	284	ALDH3B2 PRLR KIF20A AK4 GABRP ZMYND8 S100A2 PROM1 CYP2J2 KIF18B PKP1 CLGN SPDEF GINS1 PRR15L KIF14 ABCA12 PCLO STIL KRT16 E2F3 RBBP8 TYMS MYL6B LDHB MELK KIF23 CEP55 BBS1 MKI67 IGF2BP2 MSX2 TOP2A SLC2A10 ABCC5 TTLL12 TRPV6 PDCD5 AMACR KIF11 YEATS2 SIDT1 SLC9A3R1 FBL ZKSCAN1 ETFA RABEP2 INPP4B IDH2 PON2 KRT18 PPIC TNFRSF21 NAV2 EGF ETFB DAP SERHL2 FAH LRRC8D TP53TG1 ANP32E ENOSF1 S100A13 PLEKHB1 GALNT7 P4HA1 TSTA3 LIMA1 CDC20 STOML2	up	*
GO_RIBONUCLEOTIDE_BINDING	0.0000001	0.0000047	0.7049757	0.2767223	1.426928	1571	KIF1A ATP10B CPS1 PDE11A KIF12 STYK1 TRIP13 HKDC1 ABCA13 DDX11 ENTPD2 ABCC2 HELLS EPHB3 KIF20A CNGA1 DDX12P RUVBL1 AK4 DNAH2 CHEK2 BUB1B SLFN13 MYO3B PPIP5K1 NEK2 XYLB FRK POLQ UBE2T PBK KIF18B TTF2 GUCY2C PIF1 NMNAT3 IP6K3 STK36 TUBB2B TTK CDK4 BRSK1 SLC27A2 KIF14 UBE2Z RHOV ABCA12 GMPS STK31 FLAD1 PLK1 IFT27 AURKB ACAD9 ALDH18A1 PAK6 CDC6 WNK2 TRIB3 FIGNL1 MCM4 PRKCA RAB36 MCM2 RAD54B DNAH3 PMS2 NWD1 XRCC2 ORC1 AACS CCT6A MCM8 PIP4K2C LIG3 MAP2K6 SGK2 SRPK1 KIF27 INSRR EPHB1 P2RX2 DNAH14 MPPED2 CCT2 AGK AK8 SCG5 NME1 IKBKE AARS2 TTLL4 RUVBL2 MELK DYRK1B KIF23 MKI67 CUL9 SLFN5 RND2 HLTF KIF15 PCCB HS3ST5 MAP3K13 KIF3B BUB1 TOP2A CCT5 AURKA MYO10 HHAT ATR RAB19 GTPBP3 LARS2 SMARCAL1 KIF2C MCM7 IFI44L COASY ABCC5 TTLL12 PRKDC RHOBTB3 HELB RAD54L ERAL1 PKM SBK1 EIF2AK1 PHKG2 KIF11 PASK MCM3 PEX6 MCCC2 TARS2 CHD6 EGFR DNAH8 LIG1 SARS2 RIPK4 MORC2 ABCB6 CHEK1 NEK11 ASS1 ACSF2 KIF3C EPHA10 RAB13 PFKP ABCB9 HSP90AB2P MST1R KCNJ11 KHK AKT2 CNGB1 PKMYT1 DNAH11 BRIP1 DDR1 EEFSEC CAD BLM MTG1 PPP5C ATAD3C ARL16 ERCC2 TRPV4 MYO1A TRIT1 RECQL5 DYRK2 DDX56 MARK1 TNIK IKBKB DCLK1 TTBK1 CBWD6 FASTK NSF DDX51 HARS2 PAK1 LRGUK CDK1 CDK12 DNAH6 EPHA1 KIF5A UCK2 GBP3 MERTK STK32A CCT3 ATP2A1 NUDT2 TTLL9 TNK2 NAV2 TYW1 DHX37 TRAP1 ABCC11 SYN3 MAP3K10 KIF19 DNA2 ACTR3C KIF2A DHX33 ACSBG2 KIF7 ITPKA KSR2 PDK1 NEK5 ACTR3B MYO5B RAB6B AK7 ATAD3A DNAH5 PRKAA2 ABCA4 UCKL1 PSMC4 RTCB RECQL4 MAST1 ACVR1B GBP5 STK11 TEP1 GAL3ST4 ULK1 EFTUD2 DHX34 HSPA4L NMNAT2 MYO19 ACBD6 PARS2 MOV10 ANKK1 ILF2 ARFRP1 RHOC CDK3 TUBG1 ATP7B RABL2A DCAKD NEK10 NADK2 SPG7 DNAH7 DHX40 GALK2 TRMU MTOR GSS DNAJA3 ATP9A AARSD1 LONP1 DHODH TRIO TUBB2A TUBA3D KIF22 MAPK13 RAD51D EPHB2 ARF5 ACBD4 DNM1 UBE2Q1 TK1 DTYMK TUBA8 CHTF18 GBP6 CNGA4 SCN8A URGCP KIF21A CSNK1G1 LMTK2 SLC22A5 HSP90B2P NUDT16 MAPK10 TSSK3 SPAG1 KIF20B DAP3 NDUFA13 ASNS GFM2 GK5 CHD5 CDK13 TTLL10 TWF1 ACSL6 GNAZ TYRO3 ATAD5 RAB24 MAT1A ATP13A1 NADSYN1 CCT7 CDC7 IP6K2 YARS2 RAD50 ABCC10 TNK1 EP400 ACBD5 PFAS LSG1 UBE2O ABCC9 ENTPD8 DGKA IARS2 ERBB3 TUBG2 POPDC2 TTLL3 ACLY ENTPD3 ABCC3 ABCA7 FANCM MCM6 MYO5C CKMT2 WRNIP1 DYNC1LI2 KIF21B CDC42BPG SRPK2 DHX8 MCM5 NMNAT1 RAB15 ACOT11 ZRANB3 DDX23 DYNC2H1 NEK4 LANCL2 SCYL3 RAB3D ADCK1 PIP5K1A MYH7B PFKFB4 RTKN LRRK1 TTLL6 IGHMBP2 RHOBTB1 MYH3 MAB21L1 RAP2B MUSK ABCD4 PALM3 PRKD2 STK39 PI4KA STK35 DDX55 ATAD2 TSR1 DUS2 GTPBP10 RAB34 GNAL FARSA NDUFV1 MYH13 ROS1 MSH4 PMS1 ATP6AP1 MSH2 MAP3K14 ME1 ADCY1 SMARCA4 ULK4 STK38 DDX54 ABCF3 RTEL1 CDC42BPA RFC5 CSNK1G2 NUGGC GBP1 NME4 PAK4 GTPBP2 ICK ABCF2 ACSF3 NUBP2 DNAH1 HK2 TUBA4B BMS1 RAD51 HLCS ARL17B FARSB STK25 MAP3K9 PFKM ARHGAP5 NOS1 MARK4 GBP2 SNRNP200 NME7 CHD3 CDK5 GNA14 POMK RHOT2 ERBB2 NUBPL SMC2 GNA12 RAB43 PNKP ADCY6 CENPE EIF4G1 RHOD GNE SRCAP EARS2 MYO15A DDX52 HSPA7 GLYCTK NDOR1 MTHFD1 TP53 RAB25 SRPRB CBWD1 TSSK4 SEPHS1 PAICS TIMM44 EPHB4 UBE2C GPN1 NPR2 RIPK3 ADCK2 OAS3 TUBA1C PI4KB NAT10 DNM1L RABL6 TK2 TTLL5 BRSK2 KIF24 MOK ALPK1 DDX41 MTG2 MAP3K19 MAP2K2 ACSL5 NLRC5 ERCC3 PRKAG1 ROR2 SLFNL1	up	***
RIGGI_EWING_SARCOMA_PROGENITOR_UP	0.0003801	0.0059416	0.4984931	-0.2479501	-1.425781	351	DAB1 GPR17 KMO CLIC3 TRHDE HVCN1 TBX3 GATA2 WFDC1 FABP4 GIMAP8 RCOR1 LPL LMO2 LDB2 CITED2 AKAP7 SLC39A8 TBXA2R YPEL5 NFATC3 SEMA6D CD36 SH2B3 ASAP1 CARD16 HBEGF MALAT1 KCNK3 BTG2 CYYR1 PRELP FZD4 PAG1 ABHD6 SERPINB9 CES1 PDGFA KDSR ADARB1 CASP1 ZSWIM6 PEG3 PAQR5 TNFSF15 GRK5 NPR3 LAPTM5 ID2 IGFBP2 LBH CCND2 PTGER3 TM6SF1 CYP26B1 HES1 MAPRE2 ARHGDIB ID4 CREM EBF2 RNF141 RGS18 AQP3 SEC14L1 STAT4 GIMAP2 JPH1 JAK1 PTGER4 PODXL PIK3R1 PCGF5 FAM43A KBTBD8 SIGLEC15 MFAP4 MCAM CDK14 PLCG2 FOS CTTNBP2 ICAM2 EPHA3 TGFB1 TCF4 CDC37L1 DUSP5 MCUR1 PDLIM1 PCDH17 MEIS1 FCGRT RIMKLB RGS2 TCF7L1 ICAM1 GPX3 OPN3 PARM1 EPHA4 ACACB ZDHHC21 DAPK1 KIT DUSP7 NR3C2 TOX2 SPATA13 SLFN11 FNBP1 REEP1 KALRN CTSH ZBTB16 BHLHE41 DUSP6 FADS3 ATP11B C5 MAMDC2 ANKS1A	down	**
GSE3039_CD4_TCELL_VS_NKT_CELL_UP	0.0044508	0.0392395	0.4070179	-0.2678394	-1.425481	177	GPD1 SLPI PDLIM2 TMEM150B GIMAP8 CCDC88A INPP5K NEDD4L P2RY13 PDE2A SH2B3 PTS PARVG HIPK3 STOM CLK1 ZEB1 RIT1 MARVELD1 UBE2E2 CDS2 LBH PRICKLE2 IKZF5 CDKN2AIP TGFB2 PIAS1 ARHGAP17 CREBRF PHACTR2 PIKFYVE HECA MTMR14 UBAC2 CREB1 FSD2 PDZD2 CGGBP1 CELF2 HNRNPH3 UNC13D ICAM1 ANKLE2 CCR9 TRAF1 SSH2 RBM48 P2RX1 DOCK4 HEBP1 CCND3 IQGAP1	down	*
DBP_Q6	0.0019609	0.0211140	0.4317077	-0.2660771	-1.425414	192	SEMA6A ADTRP JPH4 CRY2 TRIB1 ZEB2 ERG LRRFIP2 KIAA0355 TNFRSF8 NFIX PLXNA2 NLK PPP2R2A CD93 ITSN2 GPM6A CNN1 TLE4 ADAMTS9 KLF7 ELMSAN1 DCHS1 AFF3 LIN54 FOXN3 BTG1 EBF2 MITF MN1 DDX17 MBNL2 CDK2AP2 PDZD2 GRIK1 MCAM CD151 SNX9 GPRIN3 TSHZ3 NAP1L5 SFTPC TGIF1 TPMT PCDH17 TOB1 THAP11 MBNL1 UNC13D IL18 ARRB2 SPIB PTCH1 SCUBE1 FAM13C PLAG1 BHLHE41 DUSP6 SPPL2A SVIL ZNF385B	down	*
GO_REGULATION_OF_PEPTIDYL_TYROSINE_PHOSPHORYLATION	0.0029472	0.0287570	0.4317077	-0.2604201	-1.424971	209	ANGPT4 EREG ACE TAL1 PECAM1 BDNF FYN CD44 CAV1 FGF10 NEDD9 GAS6 CBL IL23A CD36 MIR146A SH2B3 CLCF1 HBEGF ADAM17 ITGA5 SFRP1 WNT3A ARHGEF2 PDGFA LRP4 BST1 SOCS5 PTPRC EPGN HES1 IL24 CD80 CNTF PPP2CA AREG IL6 PSEN1 SOCS3 SH3BP5 ADRA1A PRKCE OSM GPRC5A CD74 TGFB1 TEC CNOT7 CD81 ICAM1 IL18 ARRB2 EPHA4 RIPK2 KIT PAK2 SAMSN1 NRG1 IQGAP1 EHD4 BANK1 CSF2 ABI1 GREM1 GHR	down	*
GSE25087_FETAL_VS_ADULT_TREG_DN	0.0047477	0.0410428	0.4070179	-0.2718955	-1.424396	157	SEMA3G LRRC8C RUNDC3B SRSF7 EOGT TXNIP ASAH1 RNF125 FZD4 LITAF ABCG1 FOXP1 MS4A1 DGKE KLF9 MED6 SPAG9 NR1D2 SELP C9orf72 PIK3C2A UBASH3B HTRA4 BACE1 MYLIP VPS37A ZNF548 HECA OXNAD1 OSTM1 IDS TNFRSF10B CELF2 CDC37L1 RPL21 IRS2 KCNA3 TAGAP TOB1 TSPO CCR6 CGRRF1	down	*
GO_REGULATION_OF_IMMUNE_RESPONSE	0.0000019	0.0000662	0.6435518	-0.2283496	-1.424242	841	GPR17 NLRC4 EREG CD300LF FOXF1 HMOX1 FCN1 GCSAML SCIMP PPARG CD55 FCN3 GATA2 PGC IL1B MNDA LPXN BTNL9 OSCAR FYN SAMHD1 FCER1A CLEC12B CAV1 BAIAP2 PRAM1 MYD88 ELF2 CD300E PLEKHA1 C5AR1 CLEC10A RBM14 ELMO1 CDC42 MARCO IL1RL1 CD1C OTUD4 PSMD5 LAMP1 CD22 SLC11A1 NFATC3 PILRA RFTN1 IL23A CD8A FGR CD36 ANXA1 MIR146A SPG21 CLCF1 IGKV2-28 ADA CD33 RAP1A CLEC7A MASP1 TNIP3 RNF125 FOXP1 HLX PAG1 MS4A1 IFNK SERPINB9 LAIR1 GATA3 PPP3CA RGCC IL18R1 TRAF6 GRN CRK CRTAM PDE4D UBE2D3 TFRC IL10 CFD DUSP3 BIRC2 SLC46A2 PTAFR SOCS5 LY96 FAM49B UBQLN1 NCR3LG1 NFKB1 CADM1 PTPRC IRAK2 SELL TLR4 ACTR3 SFTPD FCER1G CD300C SMAD7 KLRD1 IL7R HLA-DQA1 C4BPB CD300LB ACTR2 TGFB2 PIAS1 HCK NCKAP1L CD8B IGLV2-11 MYO1C CD80 ELF1 IL6 WASF2 MUC3A CD160 KLRB1 CTSS PSEN1 SOCS3 APPL1 HCST SEC14L1 CD48 C1QA JUN PSMA1 RAC2 TYROBP TREM1 HSPA1B DNASE2 IFNGR1 JAK1 RAPGEF1 CCR7 STX7 PIK3R1 PRKCE GRB2 MALT1 RC3H1 PRKACA TBX21 ZNF683 IGKV3-20 CD34 PLCG2 FOS UBB PELI1 CALM1 TNFSF13 YTHDF3 PSMD12 ICAM2 MAPK8 TREX1 CD74 CR1 PIK3AP1 SMPDL3B TGFB1 VAV3 AP1G1 CD1D ZBTB1 TEC FPR2 YTHDF2 NLRP6 PIK3C3 CD86 CNOT7 PDCD1 PPP3R1 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 BAG6 FCGRT CLEC2B PDE4B IGKV1D-39 UNC13D ICAM1 TRAC IL18 IL18RAP LAT ARPC2 FKBP1A ARRB2 RTN4 HSP90AA1 TAB2 RIPK2 NLRP3 UBE2D1 ACTB HAVCR2 PSME4 CREBBP ICAM3 CD19 TLR10 SIN3A NFKBIA KIT SIGLEC9 CD1E CD3G ARPC5 PAK2 KLRK1 AIM2 SAMSN1 THEMIS2 ITCH PSMD6 PSMD9 SFPQ PUM1 MS4A2 KLRF1 ABI1 UBE2V1 CYBA EPG5 PPP2R3C IGKV2-30 C5AR2 C1QB CTSH SPPL2A TREML1 CLEC4E C5 MAPK1 PRKCH ITGAL ITGB1 TREM2 S100A8 FPR1 NDFIP1 NFAM1 MUL1 FPR3 CD79B HLA-DRB1 WNT5A PAX5 UBE2N BCL10 MATR3 HMGB1 DDX21 FCGR3A NMI EP300 CD3E IRF1	down	***
GO_ERK1_AND_ERK2_CASCADE	0.0009714	0.0124518	0.4772708	-0.2579576	-1.424182	243	FFAR4 HCRTR1 SEMA6A RAMP3 TEK SCIMP GLIPR2 IL1B P2RY1 RAPGEF2 BMPER BMP2 CD44 CCL3L1 C5AR1 HMGCR APIP FGF10 MIR27B MARCO GAS6 CD36 RAP1A RANBP9 SIRPA SPRY2 PDGFA NODAL ARRB1 DUSP3 CCL22 NPNT KLF4 PDE8A CCL3 PTPRC ATF3 CCL4 TLR4 MIR24-2 XCL2 DUSP1 GNAI2 DNAJC27 JUN NOTCH1 ADRA1A RAPGEF1 PTGER4 CCR7 ACKR3 GPR183 FGFR4 SPRY4 RRAS CD74 TGFB1 FPR2 MIR23A NLRP6 NQO2 CCR1 NPTN CCL20 ICAM1 FGF2 ARRB2 TIAM1 RIPK2 HAVCR2 EPHA2	down	*
GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP	0.0046107	0.0402518	0.4070179	-0.2675744	-1.424070	177	KCTD9 FOSL1 PRPF38A ZBTB2 SH2B3 CD5 SBDS LATS2 CHMP1B EIF1 EIF5 BTG3 LRRC57 HNRNPA3 TPP1 PER2 CCL4 SH2D2A FAM76B RABGGTB SNN METAP1 CRNKL1 CNTN3 STAT4 IFRD1 IRF8 CGGBP1 TINF2 SNX9 SLC3A2 PSMD12 CPA3 CHORDC1 SERPINB1 VAMP4 IRS2 RELL1 APLP2 ETS2 RNF138 SLC31A1 NBN MGAT2 RBM18 TRAF1 DNAJB9 PAIP2 GSPT1 CNOT8 SNRPG CENPC CLOCK SLC38A2 ZFP36 WAC MFSD1 UBE2N DDX21 CHKA SH3BP2 TAF1D	down	*
HSF1_01	0.0030064	0.0292126	0.4317077	-0.2602238	-1.423896	209	SLC24A4 KRT81 GPR17 GREB1 IZUMO1 BMPR2 NFATC3 TRIB1 CACNA2D2 PLXNA2 EIF5 HSPB1 LUZP1 GATA3 JAM3 LAMTOR3 KANK2 ADAMTS9 SOCS2 SOCS5 CADM1 UBE2E2 DUSP1 PPP2R5C ILDR2 PTGIS TSACC RSRC2 GPBP1 ID4 CNTF CREM PIKFYVE NECAP1 JUN DNAJA1 MBNL2 ATL2 FSTL3 GRIK1 FOS HIVEP2 TREX1 TSHZ3 FLNC CHORDC1 EHD1 HNRNPA2B1 JMJD6 GLRA3 TGIF1 ATP6V1A PIM1 TMEM107 MYOCD STX12 ACTN2 VASH1 RTN1 TAB2 HSPA8 EPHA2 SREBF2 TLK1 GIMAP4 SHISA6 DNAJB5	down	*
GO_CELL_SUBSTRATE_ADHESION	0.0003151	0.0050878	0.4984931	-0.2488825	-1.423270	308	SMAD6 LIMS2 AJAP1 LYPD5 ACVRL1 FOXF1 TEK DLC1 PECAM1 ATXN3 WNT4 LYVE1 EMP2 CD44 RADIL CORO1C MYADM CDH13 CDC42 MSLN NEDD9 GAS6 RHOA APOD CD36 ITGA5 PARVG FZD4 JAM3 CRK SFRP1 SORBS3 ROCK2 SNED1 TIMM10B DUSP3 SORBS1 NPNT PTPRO LIMS1 BST1 MSLNL ROCK1 PARVB THBS1 ADAMTS9 LAMC3 AXL HPSE PEAK1 VWF SRF NINJ1 TECTA KANK1 FAM107A VAMP3 UTRN LAMB2 NDNF NOTCH1 RAC2 MAP4K4 FERMT2 CCR7 PIK3R1 PRKCE HSD17B12 ITGA11 PPM1F CD34 SIGLEC1	down	**
MIR186_5P	0.0000938	0.0018266	0.5384341	-0.2399215	-1.423108	474	COL25A1 DLC1 TRHDE PTP4A2 PID1 CGNL1 QKI GPCPD1 TGFBR3 RGPD5 OTUD4 MOB1B ACER3 PKHD1L1 UBR3 MCTP1 SLC36A4 SGMS2 MTF1 CYYR1 ZNF503 SLAIN2 FAM122A NDEL1 ZFYVE16 PDE4D PDGFA TIPARP KDSR C14orf132 FAM124B YBX3 PEG3 PXDC1 RUNX1T1 ZADH2 STK17B KLF7 PDE3B NPAS3 NR1D2 SELL CYP20A1 SHE FRMD4A PTGER3 OXSR1 ZNF706 KIAA0408 SPRYD7 KPNA3 RUFY3 PDE1C AFF1 FAM76B AKIRIN1 LIN7A ACTR2 LIN54 RAB6A SRGAP2C USP25 CREBRF PDIK1L BCAR3 NEK7 TMTC1 MN1 CCDC50 FOXN2 EPC1 DHX15 SNX2 SP3 IRF8 MBNL2 LUZP2 COBLL1 ATL2 RC3H1 FSD1L ZNRF3 DENND4A EPC2 GRIK1 PPM1F MOB1A PLCG2 NECAB1 PKD2 NAA16 SORT1 AZIN1 PDS5B GNAI1 MAP3K2 CNTNAP1 PLSCR4 C8orf37 COL15A1 TOB1 MICU3 CALB1 INO80D RNF2 AMD1 BMP2K ARAP2 RNF138 MOB3B MIER1 ABL2 CHURC1 CEP170 SCN7A EPN2 SEC63 LRP12 VPS4B TRAPPC8 ARIH1 ALDH6A1 PSME4 BCAT1 CEPT1 SCAI PAK2 DUSP7 FAM126B CAMSAP2 PUM1 SLC44A5 RAB2A ANO6 FEZ2 MIER3 MAP4 CHP1 UBR2 CCDC112 NR4A2 HIPK1 MAPK1 RB1CC1 NOG PIK3CG HEY1 PRTG API5 DNAJC8 UBE3A PAX5 ANGPT2 UBE2N SCAF11 TSC22D2 SERP1	down	**
GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN	0.0046640	0.0405343	0.4070179	-0.2673617	-1.422939	177	ABHD5 USP12 ZBTB34 BACH1 SFR1 DYRK1A ZBTB2 TGFBR2 TEX2 TMX4 PCYOX1 LMNA KLF10 CLK1 ZYG11B RHOB FOXO1 ACSL3 SLC12A4 PAPSS1 CPT1A TP53BP2 MAFF AFF1 IKZF5 RSRC2 RASGEF1B FAM102B LIN54 TOPORS MCMBP MYLIP PPP2CA WASF2 RYBP APPL1 JUN MTMR14 CPEB4 IRF8 MBNL2 MSANTD2 OGFRL1 CGGBP1 YPEL2 RUNX3 IRF5 PARD6A RELL1 TAGLN RNF2 ICAM1 TOB2 OSER1 GLUL MARC1 KIT CHCHD7 USP48 ZNF326 SLC16A10 ETFDH SERPINE1 TMEM43	down	*
GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP	0.0047173	0.0408484	0.4070179	-0.2672814	-1.422511	177	CXCL3 EREG MIR22HG TXNL1 KIAA1109 ELF2 SFR1 IL1RN TSHZ1 MAP3K8 HDC MED19 SLC25A37 PPP3CC PTPN12 CASKIN2 CLIC4 UBQLN1 NFKB1 CDKN1A PTPRC PRF1 CCSER2 SNN RPS6KA2 UFM1 APPL1 LRCH1 ETS1 IPO7 ENPP4 OSM TRAK2 RNF24 NDST1 RNF146 CD74 ING3 ZRANB1 TBRG1 HBP1 JUND IER5 TBC1D1 TTC32 ADORA2A MCOLN2 JDP2 CHIC2 ZNF800 ATF2 CLEC4E MAPK1 CLOCK FUS	down	*
MIR3609	0.0009296	0.0120174	0.4772708	-0.2496980	-1.422007	307	EPAS1 SLC31A2 TDRD6 FGD5 CLEC12A RCOR1 CITED2 EML1 SLC39A8 MTMR10 RXFP1 C3orf70 OTUD4 ACER3 TXNIP KCNAB1 CD36 SGMS2 PPP1R15B MTF1 BZW1 BTG2 FZD4 LITAF REV3L PEX5L SLAIN2 FOXJ3 PPP3CA BTG3 FBXL5 TBC1D9 SCP2 REST PRKD3 VASP FBXL3 SPAG9 AQP4 PIK3C2A ELK3 UTP23 PRICKLE2 UBASH3B MARK3 FAM76B ADD1 ACTR2 BTG1 PDK4 TMEM9B MYLIP DNAJC27 PHTF2 DDHD1 DCTN6 PLEKHA3 RAB8B NDNF C2CD2 PDE5A HERC1 FSD1L CXCL5 TMEM128 AGFG1 PKD2 NAP1L5 STRN NDUFA5 ZFYVE9 GNAI1 MAP3K2 NBEAL1 ADAM10 PHLPP2 BMP2K PDLIM5 MIER1 LRP12 EPHA4 HSPA8 UBE2D1 ZDHHC21 SSH2 NPAT FNBP4 BCAT1 RNF38 SCAI TMCC3 DOCK4 EIF4A2 ANO6 TRIM36 MED17 ZFYVE26 ZNF800 CLOCK PRKCH ITGB1 YWHAB PTDSS1 CEP44 LAMP3 GPR137B PDE7B TRIM13 RAD21 TES EP300 TYRP1 SMARCA5 B3GALNT2 ZFYVE21 SETD2	down	*
GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0054227	0.0453481	0.4070179	-0.2683613	-1.421771	173	ST8SIA6 ST6GALNAC3 GFOD1 STX11 LACTB PTPRM SLC3A1 GM2A RB1 ADAMTSL4 CYBRD1 STAT5A ARRB1 AHNAK FOXO1 YBX3 KLF9 SOCS5 ITIH5 SSH1 ATL3 SELL NINJ1 MYO1C NSMAF IL2RB NDNF STAT4 CPEB4 PTGER4 EEA1 RTN4R LETM2 TOM1L2 GRSF1 PELI1 NKG7 IRF5 TGIF1 TEC CTIF STON1 SELPLG SESN1 ITGAE TRAF1 TMEM184B BCAT1 KIT RORA NRP2 RNH1 FCRL1 JDP2	down	*
HOXA1_TARGET_GENES	0.0000074	0.0002143	0.6105269	0.2786542	1.421735	959	SYT8 STYK1 FAM24B IGSF9 KCNK5 DNAH2 CCDC127 PAIP1 PDCD2L SEMA4B NDC80 MKS1 SRGAP3 TBRG4 BET1 THEM4 CREB3L4 METTL1 GINS1 CDCA2 IFT122 ANLN SNF8 ANKRD24 FLAD1 IFT27 CDCA8 ALDH18A1 ESPL1 FIGNL1 SPATS2 PMS2 CKLF-CMTM1 EIF3B MIS18A KIAA0895 ZNF3 DZANK1 LRRC27 CCT2 LSM5 FAM220A HAUS5 RANBP1 ASAH2B RUVBL2 CCDC150 CISD1 XPNPEP3 NOP9 SDHA BOD1 F2RL1 TP53BP1 PCCB FBXW9 FRS2 MAP3K13 IQCD NUP155 MYO10 C1orf226 ZNF174 CENPW TPCN1 NSUN2 SETDB1 ZNHIT6 KLHDC4 FANCD2 LINC00857 TRPT1 LMNB1 SEC61A1 AIMP2 EMG1 PYCR2 TARS2 WDR60 BCL2L2-PABPN1 SPINT1 C7orf50 IFT172 TRMT61B CENPO COX19 EHHADH DCTPP1 XRCC1 PIH1D1 TRMT2A RAD18 FDXR MTG1 PHB ERCC2 PIGO SPRY1 SRRM5 UQCR11 RECQL5 CKLF RNF216 CKS1B MRPL36 CDKN2C HARS2 ING4 PABPN1 HDGF WDR5B DNAH6 CENPJ CENPH AP3D1 PICK1 PHF12 ADAP1 NBPF3 GTF2E1 ACP6 SMG9 CMTR1 PRPF6 AP5Z1 KIF2A SDCBP2 ENPP3 ZNF584 ANKRD26 LARP1 CPNE1 TMEM79 TNPO2 FADD METTL3 ATAD3A TTC16 CBX1 SRD5A1 UBN2 ZNF692 RANGAP1 CHCHD3 LGR5 PARS2 MZT2B DENND6B SPEF1 ILF2 DCAKD SMG5 COA3 SLC26A2 ADNP PUS1 ADAT1 ZNF133 MAN1B1 MBD4 MRPS34 S100A16 LONP1 PIGG GPRC5C CCDC130 COX7C FBXO4 CENPQ AGPAT5 DAP3 KRBA2 GFM2 TM9SF4 CKMT2-AS1 CDK13 C12orf73 MAGOHB PARP9 CCT7 CDC7 KLC4 CLDN12 SUPT16H DHRS1 PFAS CPSF4 TMEM106B NPRL3 GBF1 MAN2A1 FAF1 LRRC59 GPATCH4 ASCC1 ACLY ZNF497 MRPL24 MCM6 MYPOP KDM4B CENPT NOB1 RPPH1 KPTN WDR35 ANKRA2 MALSU1 LTV1 HAX1 C1orf109 ZSCAN32 TMUB1 NEURL4 POLR2I CYP4F12 MED27 SF3A2 DDX55 GOSR2 TSR1 DUS2 SPSB3 GTPBP10 KLHL7 ZNF580 NDUFV1 MICAL3 RRNAD1 NCDN SMARCA4 RBM42 RN7SL1 HDLBP ZNF169 DTX3L DENR CDK5RAP1 ABCF2 ABHD10 UQCRC1 AP001372.2 INO80E NUBP2 N6AMT1 TTC1 TRIP4 BRMS1 COPA ZNF217 SUPT3H SAMD4B KIAA0825 TCF25 ACP1 SNX8 CTTN NUBPL TBCB ALDH3A1 SIRT6 RPN1 XPC DNAJC14 ADRM1 POP4 SMPD4 NDOR1 GGCX NMT1 TIMM44 RANBP3 MRPS27 TBL3 UBE2C DCDC1 MSRB1 RFT1 ENO1 SLC39A1 NAT10 TK2 TTLL5 TRUB2 FAM222B SCAF1 ATG4B COX17 CALU MOK MTG2 FTSJ3 FBXL18 ERCC3 ALKBH2 PARP2 HEXIM2 VPS18 MORN4 USP20 DHDDS MROH7 MLH3 MAN2C1 METTL4 SH3RF2 FAF2 EIF2B1 CDK11B ADSL NUDT22 SRI HUWE1 ROPN1L RAB11FIP3 ATRIP OPA1 SAFB MRPL2 SLC4A1AP STARD10 GLRX5 LINC00271 TYK2 NPM1 GCC1 PRCC ZNF425 RPS6KB2 GAK ARFIP2 SAFB2 TMEM214 CXXC1 SLC27A5 ZNF805 CACTIN MAP3K5 WDR89 CCDC86 NAE1 PLEKHJ1 SIX5 TTC13 TMEM175 THAP4 C1orf74 ARL1 SRSF9 REEP4 STEAP2	up	***
MIR524_5P	0.0000046	0.0001440	0.6105269	-0.2236029	-1.421440	812	AJAP1 MGAT3 SC5D IL1A SGK3 TAL1 SECISBP2L CPEB2 LTA4H SLC16A4 PTPRE LIPA PTPRB ZBTB34 TMEM170B BDNF PLEKHF2 MED4 DDX6 QKI DYRK1A CDC42 FBXO3 GNPTAB TSHZ1 TET2 NFATC3 SPCS3 HEG1 TMX4 ZEB2 TXNIP ARHGAP29 WWC2 ATP2B1 LACTB CACNA2D2 LATS2 RAB33B BZW1 MAP3K8 RANBP9 COX18 KLF6 RNF182 GLS CAV2 PTX3 CAMTA1 ADIPOR1 EIF4E DACH1 FOXJ3 PPP3CA RGCC SRSF2 LHX6 HNRNPDL TFEC HNRNPU TCF7L2 UBE2D3 TFRC RAB14 ZYG11B GPM6A ZMIZ1 PTPN12 MSR1 TLE4 RAB12 FOXO1 DGKE SCP2 BNIP2 TCP11L2 ACSL3 KLF4 FAM76A REST PRKD3 DRAM1 TJP1 SEC24B C1QTNF7 PER2 LRRC40 IRAK2 CYP20A1 PNRC1 CEP57 ZBTB43 CLK4 UBE2B MBD2 RAP1GDS1 SLC6A6 PRICKLE2 OXSR1 UBASH3B PAFAH1B1 BCLAF1 SMNDC1 FAM76B AKIRIN1 EFR3A CNOT6L RSRC2 CNRIP1 NCOA1 SIAH1 FAM102B USP25 RBM39 GPBP1 CREBRF PRKRA SCEL ID4 ELF1 PDIK1L CREM YBX1 DDHD1 SGK1 HSD17B13 EBF2 HCFC2 PPP6C SERPINB8 JUN ARL5B MITF STAT4 C20orf194 GABPA GLUD1 DDX17 C11orf58 BMP3 MSRB3 HSPA1B OSTM1 EPC1 SKIL ENPP4 SP3 ACKR3 CREB1 ZNRF3 PREX2 CGGBP1 MEAF6 AGFG1 CTTNBP2 PELI1 AZI2 HIVEP2 USP7 PPTC7 MAPK8 PKIA RIN2 TTBK2 BTBD7 EPHA3 SORT1 GOLGA8R VAV3 TCF4 ATG2B SERPINB1 VAMP4 RSBN1L SBF2 GOLGA8H ZC3H12D ATXN1 CSDE1 PPP3R1 GNB4 GNA13 KAT2B ADAM10 PDE4B CALB1 ETS2 MBNL1 ATAD2B ARPP19 SMAD2 INO80D RNF138 SESN1 INTS6 SLC34A2 ZNF583 CEBPD LRP12 TRAPPC8 TAB2 FBXO30 ARIH1 MEGF9 HNRNPK G3BP2 GRIN3A SRSF10 KPNA4 VSIG10 NPAT TTC28 DOCK10 SCAI FAM126B KIF1B RORA FAM13C DOCK4 RHOT1 SFPQ GSPT1 CNOT8 WDFY3 PUM1 EID1 SLC44A5 MIS18BP1 SPATA13 INTS10 ZBTB44 IRF2 HNRNPH1 VPS13D PSIP1 EGR1 TMEM50A DUSP6 TMEM30A ZNF106 CENPC NR4A2 HIPK1 ATF2 UBA6 MAPK1 SSB CLOCK	down	***
VERHAAK_AML_WITH_NPM1_MUTATED_DN	0.0020669	0.0219846	0.4317077	-0.2608727	-1.421296	207	DPYSL2 FCER1A CAV1 CLEC10A MEF2A MSLN CD1C AGTPBP1 HSPG2 ABCB1 ERG PTPRM CACNA2D2 TMEM204 HSPB1 ADIPOR1 DACH1 GATA3 GNG7 SPTBN1 PTGIR FOXO1 GPA33 RUNX1T1 PRKD3 MPL NPR3 GMPR PDE3B HOPX CCND2 TM6SF1 DSE MYH11 DCHS1 HLA-DQA1 RPS6KA2 TMOD1 C2CD2 CD48 HPGDS MN1 PALM PTGER4 GYPC CD7 CST7 CD34 RUNX3 XYLT1 TGFB1I1 GNAI1 GALC PDE4B ARAP2 LDLRAD4 EGFL7 TFPI SPIB ALDH2 CD19 KIT FGFR1 LPAR6 EHD3 BANK1 PMAIP1	down	*
GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP	0.0036831	0.0340941	0.4317077	-0.2714418	-1.421231	166	SNX10 RAPGEF2 EFCC1 FOSL1 WBP4 TRIB1 EDEM1 DNAJC18 CARD16 ADA PPP1R15B ZNF697 NDEL1 BTG3 CD58 PTPN12 PLAUR ST3GAL2 COQ10B PLEKHM3 CDKN1A IRAK2 PER1 INHBA N4BP1 PEF1 HCK BTG1 TMOD1 PKNOX1 COPS2 PDCD6IP ETV3 PTGER4 LYRM1 OSM RAB8A TNFRSF9 TAGLN2 CALM1 PIK3AP1 LRRC32 ADPGK PITPNA ICAM1 MIER1 TNFAIP8 ELOVL1 B3GALNT1	down	*
GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_UP	0.0040615	0.0366017	0.4070179	-0.2830322	-1.420811	136	ENDOU CPEB2 DPYSL2 YPEL5 DYRK1A ANAPC15 PDE2A KCNAB1 RAPGEF4 NAAA RASGRP4 GM2A IL18R1 KIF1C FOXO1 PSTK KLF11 DAB2 MVB12B BCHE PLBD1 SNIP1 ITGAX LBH HES1 ADD1 EMP3 RPS6KA2	down	*
GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN	0.0060480	0.0492954	0.4070179	-0.2678157	-1.420359	182	CD44 CTSW ST3GAL6 STX11 BCL2A1 PDE2A ANXA1 B3GNT5 NDUFAF7 ENTPD1 ZDHHC2 LAIR1 IL18R1 TXN PPP3CC MAP2K3 NRARP AHNAK YBX3 PLEKHM3 OSTF1 TMBIM1 VIM HOPX ID2 RECK KLRD1 HGSNAT NEK7 IL2RB STAT4 GLUD1 HIC1 IFNGR1 PTGER4 PTGER2 DYM CST7 GPRIN3 SLC25A24 RRAS GSAP LGALS3 NQO2 DBNDD2 RBL2 IL18RAP CDC42EP3 CYB5R4 ARHGAP18 HIGD1C TRAF1 METTL7A TMEM109 LYST MCOLN2 RORA	down	*
GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_UP	0.0048705	0.0419204	0.4070179	-0.2698959	-1.420135	168	SLC16A12 F2RL3 SNX10 PID1 TRPV2 LMO2 ECSCR TBXA2R CASP12 SLC11A1 GGA2 ERG EDEM1 PKHD1L1 ADA LAIR1 EIF1B SNED1 CASP1 DRAM1 LY96 CTBS HPSE GNAI2 BACE1 ARHGDIB NCKAP1L CTSS HCST HMBOX1 HK3 CTSZ TYROBP IRF8 SDHD IDNK UVRAG SMIM20 SMPDL3B EPHA3 TGFB1	down	*
ZNF250_TARGET_GENES	0.0009245	0.0119588	0.4772708	0.2870787	1.420066	486	HMGA2 COL17A1 PKP2 RUVBL1 SPINK13 BUB1B DOC2A C17orf75 SEMA4B NUDCD3 RGMB-AS1 MRPL46 ANKZF1 FLAD1 TTC26 CEP70 NUF2 ACY1 GINS4 NCAPD2 ZWINT CCT2 NME1 WDR62 C5orf34 BZW2 TMEM184A RFXANK EME1 IQCD GTPBP3 MAD1L1 COASY TPCN1 RBM28 MRPL3 MRPL27 TARS2 LETMD1 WDR60 NME5 EME2 ACTL6A SCAMP5 GAS8 PIH1D1 THAP10 MRPS11 CAPN8 NUSAP1 HARS2 SUPT5H KRT18 ANAPC5 PABPN1 SSBP1 PHF12 ADAP1 STX18 TRIM41 ENPP3 CYCSP10 ATAD3A GOLGA5 NOP2 WDR24 ZNF692 FANCG RN7SL449P VIPAS39 SLC26A2 JOSD2 ZNF133 MRPS34 LONP1 MORN2 MLEC MTND5P11 ITFG2 STX18-AS1 TEKT3 DNAJC11 DNMBP CKMT2-AS1 C12orf73 PRRG2 ZBTB45 SLC1A3 COPS6 SH2B1 TADA3 EFCAB7 LIMA1 VPS25 ORMDL2 FBXO22 KRT8 METTL2B ZNF446 NOSIP KPTN SNRPD1 SLC35A3 RTEL1-TNFRSF6B LRCH4 STMN3 NDUFS7 MRPL51 RGMB SLC41A3 TCERG1 SPSB3 MICAL3 NME1-NME2 PRPF18 RPS26 NFRKB DBNL RTEL1 DENR RFC5 STAT6 CDK5RAP1 PRPF31 VPS33B NUBP2 BMS1 ZNF384 TRIP4 FBXW11 SNRNP200 BCAS3 BCL6 GOSR1 ZSCAN29 ANKMY2 ZMAT2 LRSAM1 GDPGP1 FIS1 PPIA RAD1 MRPL48 ATF7IP TRUB2 SART3 HEMK1 BRIX1 ZNF562 DNMBP-AS1 COPE INO80B DHX57 ANO8 NOXA1 ZC3HC1 HUWE1 OPA1 NSL1 EEF1A1P32 ZNF774 MAD2L1BP LZTS2 NPM1 TEFM RPLP0 PCBP4 CS TIPIN MTF2 TXN2 LRPPRC FAM149B1 MCCC1 PPP2R1A BNIP1 TMEM102 DDX49 SLC44A1 SLC12A9 TUBGCP5 EBNA1BP2 COQ4 ZNF302 OIP5 COA6 MPLKIP ABCB8 WBP1 KLHL20 KHSRP HOXA-AS2	up	*
GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP	0.0039943	0.0361780	0.4070179	-0.2670314	-1.419801	175	MS4A7 KCNA2 RBMS2 FABP4 ENG ARRDC4 ABCB1 RRAGC MALAT1 CLEC7A ZNF503 STOM TRAF6 SRGN CST3 TIPARP TRIM46 SCAF4 DUSP11 DUSP1 CPT1A MBD2 CMTM6 NCOA1 PIAS1 ARHGAP17 PKIG SGK1 NKD2 UTRN NXF1 MTMR14 JUNB MORC3 TSPYL1 IP6K1 RIN2 BAZ2B VPREB3 SBF2 LGALS3 CCR1 KAT2B RASSF8 JMJD1C ANXA11 TMCC3 ITCH ZFAND2A	down	*
E2F2_TARGET_GENES	0.0000024	0.0000828	0.6272567	0.2771556	1.419798	1186	ATP10B COL17A1 PRR15 SYT8 PTPRZ1 DDX11 FAM227A KIF20A DDX12P CDH17 HJURP PKP2 TICRR MCM10 RPGRIP1L BUB1B CCNB1 CENPF IGF2BP3 APOLD1 DDX11-AS1 SEMA4B TTF2 PHF14 PLEKHA6 METTL1 TMC1 GINS1 C6orf141 EFNA3 NOL12 STK31 PCLO EIF2B5 COL7A1 FLAD1 TTC26 NUF2 AURKB CENPA CDC6 TPX2 MCM4 LSR XPNPEP1 FERMT1 NWD1 EIF3B DTL GON4L MCM8 LIPE-AS1 NCAPD2 AVL9 MYL6B CDK5RAP3 AOC1 UQCC1 LSM5 KCNG3 KAZALD1 TJP3 MANSC1 ASAH2B POLR3A ZSCAN2 BZW2 LTB4R2 NUDT1 C19orf48 RPAP1 ZFYVE27 SPAG16 KIF15 AP4M1 KNTC1 FRS2 TIGD4 BRAT1 TOP2A RFXANK EME1 SAE1 ATR GTPBP3 SMARCAL1 MCM7 E2F2 POC1A CLSPN WDR78 ABCC5 RGL1 LIPE MMS22L PRKDC RAD54L MRPL27 KIF11 FANCD2 LINC00511 CCDC58 EMG1 ZNF785 MYRFL RNFT2 WDR60 BRI3BP TOPBP1 ARHGEF38 CBY1 DNAAF3 SPC24 AKT2 C6orf223 FDXR GRHL2 PHB COMMD4 FADS2 NAA40 C2CD3 SRRM5 UQCR11 PPP1R37 MYO1A INCENP EFCAB11 NCAPG2 CDKN2C MEA1 SUPT5H ASF1B MRPL37 C2orf50 CDK1 PABPN1 HDGF CDK12 SSBP1 PPIC CEP97 MCTP2 EXOSC2 RFWD3 WDR54 PHF12 ZSCAN25 AAGAB SUN1 LINC00894 REEP6 ZNF815P CCNJL MRPL17 PRR14L ENPP3 ZNF584 TMEM79 TNPO2 POC1B LINC00649 TTI1 ATAD3A UQCC2 HMGXB3 DIAPH3 VPS72 TSPAN1 CENPP C9orf43 IFT52 KPNB1 CHCHD3 TPD52L2 RNF44 DHX34 POLR2H MYO19 ZSCAN9 ZNF687 PARS2 CEP63 CAPS2 INTS7 EDEM3 DPP3 CDC23 DCLRE1C SATB2 SMG5 SEC16B MTOR ZNF133 SNRPA FHIT UROS LONP1 ARHGAP32 CCDC151 PKP3 GPRC5C MRPL11 IQCG PPOX PLEKHA8 ENAH PCSK4 NFATC4 CASP7 CENPQ RHBDD3 MLEC SLC22A5 IQCK ANP32E TCEA1 GFM2 C15orf41 IQCH FKBP14 CDK13 SIL1 C12orf73 NUP85 CEP128 PRRG2 CCDC159 PPME1 ENC1 ELAC2 CDC7 IP6K2 YARS2 NIF3L1 SLX4IP NR6A1 CENPK CLDN12 KLHDC3 SH2B1 TADA3 EFCAB7 LIMA1 CKAP5 BRD8 RPRD1B AHCYL1 WDR34 RIN1 EFHC1 FAF1 GPATCH4 POP7 PPP6R1 CDK5RAP2 KRT8 MCM6 ZNF320 MGME1 KDM4B PLEK2 STAMBP METTL2B PPCDC CYP2S1 UBL7-AS1 LPCAT4 CENPT CKAP2 NSUN6 NOSIP MCM5 CD2BP2 TDP1 SLC35A3 SRSF1 GINS3 LRCH4 HOXA-AS3 AATF PRSS16 DUS4L MRPL51 ETV6 SUGP1 SH3BP5L ANK3 SF3A2 STK35 ATAD2 GOSR2 U2AF2 EPCAM GNAL KLHL7 LRRC14 AP2S1 SH3D21 MICAL3 AMN1 GLO1 B9D1 RPS26 RRNAD1 MSH2 MAP3K14 CCNA2 NCDN PRR11 BANF1 CAP2 GTF3C2 SNRPD2 DOHH NAV1 PAK4 CCDC9 ABHD10 VPS33B OSBPL10 TTC1 TRAPPC9 ZNF384 TRIP4 PFKM ARHGAP5 KIAA0825 SNRNP200 SNX8 TBC1D32 NUBPL CPOX UBAP2L ATG2A SMC2 BCAS3 POLR1B BCL6 TMEM260 MAU2 CENPE TCF3 ANKMY2 SRCAP	up	***
GSE20366_EX_VIVO_VS_DEC205_CONVERSION_DN	0.0039943	0.0361780	0.4070179	-0.2669234	-1.419226	175	RAMP3 ST8SIA6 OTUD1 PLEKHF2 SFR1 ADAM17 RAB33B ACOT2 REV3L FOXP1 PAQR3 MS4A1 ADRB2 ZYG11B KLF4 KLF9 ATF3 C9orf72 PNRC1 ELMSAN1 AFF1 IL24 TOPORS RBM39 MYLIP ETF1 SGK1 LRCH1 CCR7 LSM1 STX5 GPRIN3 KLB FOSB FAM204A PIK3AP1 ING3 ZCCHC10 IRS2 C16orf72 PIM1 TAGAP RGS2 GRK4 NRN1 PDE4B PIP4K2A RIPK2 TDRP TRAF1 C7orf31 DNAJB9 BANK1 USP48 FHL5 NR4A2 FUS MYH10 SLC38A2 TUBA1A CALR CTR9 TSC22D2 MEF2D CCNYL1 SLU7 PLA2G4F LRP1 NOL11 RBM4B ST3GAL1 FAM107B	down	*
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3	0.0002382	0.0039921	0.5188481	0.2823267	1.418320	632	ATP10B PRR15 CEACAM1 PCSK6 PTPRZ1 B3GALT5 LINC00342 SLC16A14 MUC13 HS3ST1 SLC16A9 FUT6 C1GALT1 OR7E14P GMDS BDH1 PAX9 EPN3 LRIG3 ZMYND8 CP GALNT6 EYA2 TRNP1 PTPRN2 FUT3 WFDC2 TOX3 CLGN PTPRH LCN2 MUC5AC AGFG2 ASIC1 SLC27A2 ILDR1 BCAS1 BAIAP2L1 PAK6 GOLGB1 C4orf19 PRKCA XPNPEP1 PLEKHA7 EFNA5 HPS3 CIB1 TMCC1 MUC20 PDE9A B4GALT4 LRRC31 AOC1 KCNG3 CYP3A5 PLEKHS1 GOLPH3L MANSC1 TTLL4 TMEM41A GOLPH3 OSBPL2 GFPT1 IGF2BP2 BPIFB1 KLHDC7A CPD TPCN1 RGL1 BRPF3 SLC4A11 WDR72 OAZ3 B3GNT3 HEBP2 KDELR2 IFT172 STEAP4 C2orf72 TBC1D8 BACE2 CAPS EHF PTGFRN IDH2 SPRY1 DYRK2 PTPN3 PRRT3 NSF PAK1 LRRC6 CLMN ZNF652 GBP3 FAM114A1 EEPD1 ABHD17C DCBLD1 ADAP1 OAT STEAP1 MIR570 SDCBP2 NARF CNOT11 SLC44A3 SLC2A13 MYO5B RAB6B FER1L4 OCIAD2 CXCL17 RTP4 TSPAN1 DAP SNCAIP TBC1D9B ST14 RGS17 ATP7B CTSV TMTC2 CASP7 LMTK2 S100A9 SPAG1 SRD5A3 GALNT3 GK5 EPB41L4B GALNT7 ENC1 CNDP2 CLDN12 CENPV GOLM1 PLD1 PPP1R3D ENTPD3 ABCC3 CLINT1 ZNF320 BLCAP DPY19L2 ADD3 SCYL3 SNX11 CREB3L2 ETV6 WDR45B STK39 TMEM45B CORO2A TC2N C1QTNF3 CDRT4 KLHL7 SPAG4 CEACAM5 PRPF18 LRP11 FAM3C TMC5 LPIN1 AP001372.2 OSBPL10 TMEM44 SNX7 TRIP4 LRRC8B ARHGAP5 FBN2 SCOC ECHS1 RUNDC1 RDH10 TRAK1 AIFM2 NME7 FAM118B GNA14 HOXB2 SLC12A2 UQCRQ ENTPD7 SYNRG LIF GNE ANKMY2 CGN PGPEP1 ALG1 ANKS6 NSUN7 COPZ2 TAX1BP1 MUC1 WIPI1 PLIN5 PTPN13 ACAD8 KLHL2 ERCC3 PCTP ERLIN1	up	**
MIR4492	0.0031203	0.0300227	0.4317077	0.2943594	1.418315	338	SLC9A3 PPM1H PCDHGA10 CPLX2 PKP2 ARMC3 PCDHGA9 JPH3 PCDHGA5 PCDHGA7 SDK2 SMPD3 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 PCDHGB6 CUEDC1 PCDHGB4 PCDHGA11 PCDHGA8 TNC SYT12 OSBP2 TMEM41A STRA6 PAQR4 PCDHGA12 BRAT1 PCDHGC5 PCDHGC4 ZNF594 PCDHGA4 PCDHGB7 SDK1 PKM PCDHGA3 SMYD5 PLXNA1 ZNF618 CLIP3 HES6 EEFSEC PML TMEM178B TTYH3 MGLL ZNF346 PPIL2 IGFBP5 PACS1 FBXO41 RUFY4 LARP1 GPRIN1 RAB6B PCDHGA2 CENPP ARNT2 ACVR1B SRD5A1 RNF44 ZNF454 NMNAT2 FOXK1 COL1A1 ALX4 NDUFA11 NFASC NGFR EPHB2 DNM1 COPS7B TJAP1 MAP6D1 CHD5 SLC1A3 PPME1 COX10 PCDHGB1 MDGA1 CADM3 ASB6 KCNIP3 NAT8L KIF21B CABP7 TBC1D16 EDAR TTLL6 VWA3A SH3PXD2B STRBP CEP85 CAPN15 ENGASE APC2 DDX54 PAK4 ABCF2 ACSF3 TRAPPC9 SAMD4B TYSND1 SNX19 PTPRF MAPK8IP3 TRIM62 NPTX1	up	*
GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN	0.0041959	0.0375393	0.4070179	-0.2715847	-1.417715	158	SEMA6A ACE COQ2 TGFBR3 SCARF1 LRRFIP2 KIAA0355 COQ7 CSGALNACT2 HIPK3 IL18R1 SPTBN1 CLK1 BTG3 SORBS3 FOXO1 YBX3 USP2 KLF7 MYO1B ERP44 NPAS3 IGFBP2 ARAP3 SLC25A32 PI4K2A TOPORS DCP1A BCAR3 SH3BP5 AK1 IPO7 PABPC4 CST7 SNRK SLC3A2 CLUHP3 LMCD1 TNFSF13 ICAM2 SORT1 OSGIN1 MEIS3P1	down	*
GSE22025_UNTREATED_VS_TGFB1_TREATED_CD4_TCELL_UP	0.0055484	0.0462329	0.4070179	-0.2694415	-1.417201	164	EPAS1 DLC1 LTA4H SLC16A4 INSIG1 ARHGEF15 LY86 BMPR2 SLC39A8 RBM14 RPL23AP53 NFATC3 DDO IER2 TMPRSS6 ANXA1 HBEGF MAP3K8 PBX3 ATP6V1H SLC7A8 CLDN5 ATF3 SELL XCL2 MATK SH2D2A TP53BP2 VWF JUN TMPRSS11D GPR183 GPRC5A ACSL1 SLC3A2 CDK17 PKIA TIMP2 TEX30 GNAI1 GRK4 PHLPP2 SMAD2 RAB5A TIAM1 DIXDC1 GPD1L SREBF2 ANXA11 GRB10 GRPEL1 SNRPG STARD13 SERPINE1	down	*
GSE27896_HDAC6_KO_VS_WT_TREG_UP	0.0054058	0.0452952	0.4070179	-0.2705132	-1.417155	157	KCNA2 LRRFIP1 BAIAP2 TSHZ1 KIAA0355 ATP2B1 HECW2 MAP3K8 SPRY2 ARHGEF2 ARRB1 ZADH2 NR1D2 CCL4 PEAK1 NCOA1 ARHGAP17 PKNOX1 UTRN ETV3 LRCH1 GABPA UHRF2 FOXN2 CREB1 HOMER1 SNRK AGFG1 HIVEP2 STRN TGIF1 CNTNAP1 APLP2 KAT2B GEM SFT2D1 NSUN4 MEX3C STK4 PAK2 PUM1 MIER3 SPATA13 MED17 ARHGEF18 ABI1 SETX DUSP6 PRKCH KMT2E ATP1B1 FAR1 XPO7	down	*
GSE37301_MULTIPOTENT_PROGENITOR_VS_PRO_BCELL_DN	0.0035979	0.0335968	0.4317077	-0.2685195	-1.416759	171	ARRDC4 TMEM170B PDE1B AKAP7 MOB1B TEX2 LMNA LATS2 GM2A NMUR1 GATA3 TFRC TUBB6 KDSR ADARB1 LRRC57 SORBS1 NPNT PTAFR ST3GAL2 PXDC1 TPP1 PDE8A IRAK2 PI4K2A CD80 AREG CREM PHTF2 COPS2 KIF13A CNNM2 SNX29 GLUD1 PODXL RPS6KA1 AGPS DDHD2 TEX30 TEC TSC22D1 BMP2K CEP170 RAB5A FBXO30 TMX2 KIT FNIP2 EHD4 TMEM43 HMGCS1 PTGS1 CD69 FANCC SLC43A3 ATP8A1 RAB1A KATNAL1 DUSP22 SRXN1 NFKBIZ ZFP1	down	*
LEE_RECENT_THYMIC_EMIGRANT	0.0052828	0.0445412	0.4070179	-0.2614347	-1.416487	199	SIDT2 DENND5A P2RY1 KLHL8 TMOD3 CCRL2 CBL HEG1 RBM7 TRA2B RNF144B ZBTB21 GATA3 SLC25A37 CD93 SPRY2 PDE4D MPEG1 GPA33 YBX3 ANKRD10 STK17B ID2 CEP57 N4BP2L1 UBASH3B TAF13 SOCS3 JUN ARL6IP6 ATP11A PTGER4 CCR7 PCGF5 TAGLN2 ZCCHC9 ING3 TIMP2 VAV3 TCF4 NAPSB GNAI1 MCUR1 PDLIM1 GNB4 TOB1 CRY1 HACE1 RNF138 METTL21A CCR9 DAPK1 FNIP2 B3GNT2 THRAP3 GPR171 RPL18A TOX2 NIPSNAP3A	down	*
MIR27A_3P_MIR27B_3P	0.0000773	0.0015570	0.5384341	-0.2349413	-1.416382	528	PRMT8 SLC24A4 RAB11FIP1 SEMA6A STAC MS4A7 ENDOU PPARG GATA2 SNX10 RAPGEF2 ST6GALNAC3 SIK1 CDH5 ARRDC4 ZBTB34 TMEM170B ST3GAL6 KIAA1109 LONRF1 QKI HMGCR DYRK1A KCNN3 NR3C1 TGFBR3 RGPD5 HEG1 ERG SEMA6D ATP2B1 HBEGF BEST1 LIFR ASAH1 ITGA5 BTG2 FZD4 LITAF CAMTA1 SLC7A11 ABHD6 GATA3 SFRP1 SPRY2 ITSN2 SOX7 SLC7A2 TAPT1 NRARP FOXO1 BNIP2 ZCCHC24 CDIP1 SSH1 MGAT4A PDE3B NPAS3 NR1D2 ARHGEF26 SHC4 SHE PTGER3 RNF139 PEAK1 KPNA3 RUFY3 NRBF2 FAM76B AKIRIN1 SNN ZNF426 BTG1 USP25 PDK4 TMEM9B CREBRF DCP1A SLC25A25 ID4 PDHX CCNY RYBP DNAJC27 PSEN1 RNF141 SLC9B1 NXF1 NECAP1 C2CD2 PSMA1 C20orf194 HIC1 C11orf58 BMP3 DDX5 GRB2 CREB1 KBTBD8 RC3H1 HSD17B12 TSPYL1 GFPT2 CELF2 AGFG1 POGLUT1 NIPAL4 NECAB1 FOXO3 SLC35F1 FOSB PKIA AKIRIN2 VAV3 PDS5B RSBN1L SBF2 SLC24A1 NPTN GATA6 KAT2B TMA7 PHLPP2 ATAD2B INO80D AMD1 GEM GLTP ABL2 CDC42EP3 TRAPPC8 PTCH1 VSIG10 MAP3K4 LYSMD3 MARC1 RNF38 SCAI EPB41L4A CECR2 TLK2 PRKG1 MMD PAIP2 NRP2 C1orf52 NABP1 LPAR6 GSPT1 SMAD4 MIER3 CACNA2D3 HSDL1 SPATA13 FCRL1	down	**
GO_RESPONSE_TO_HORMONE	0.0000042	0.0001350	0.6105269	-0.2262844	-1.415856	767	SLC6A4 HCRTR1 EREG ZNF366 RAMP3 LPIN2 TEK EDNRB PPARG ADTRP HHEX SFRP4 CPEB2 WFDC1 IL1B LHCGR CAT ADCY9 RDX ADCY4 PTPRE RAMP2 PID1 ENG KL PCSK9 FYN LPL EGR2 LMO2 RGS9 INPP5K CAV1 BAIAP2 FOSL1 CRY2 VAMP2 ADCYAP1R1 TBXA2R RBM14 FGF10 PRKAR1A RXFP1 NR3C1 TGFBR3 IL1RN CBL TGFBR2 CASP9 RHOA TXNIP ANXA1 SSTR1 ATP2B1 LATS2 BTG2 ANXA5 ABCG1 FOXP1 CAV2 ADIPOR1 EIF4E NR4A1 RB1 NFE2L2 NDEL1 CRK SFRP1 KANK2 EPM2AIP1 HNRNPU ATP6V1H ATP6V1B2 FOXC2 NODAL IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 PTAFR REST KLF9 ROCK1 DAB2 THBS1 ARNTL BCHE SOCS2 ATP6V1D NFKB1 CDKN1A PDE3B NR1D2 SIK2 ATP6V0D2 IGFBP2 LBH PER1 DUSP1 PIK3C2A INHBA ADIPOR2 MBD2 GNAQ GNAI2 TBC1D4 ANXA3 NCOA1 TGFB2 MMP19 GLB1 PIAS1 GNRH1 SRF BTG1 PRCP SLC25A33 PDK4 UFM1 KANK1 MYO1C FAM107A CREBRF ADCY2 AREG IL6 CTSS SOCS3 APPL1 RAB8B RWDD1 JUN DHH STAT4 NOTCH1 RAB31 USO1 GAS2L1 ETS1 ADRA1A DDX17 ATP6V0B JUNB DNAJA1 PTGER4 CCR7 PIK3R1 DDX5 PRKCE GRB2 CREB1 PTGER2 RAB8A MT-ND3 PRKACA EGLN2 ACSL1 FOS ATP6V0D1 RHOQ CACYBP FOXO3 SRSF6 FOSB DDX18 HNRNPD SORT1 TIMP2 STXBP3 TGFB1 NR2C1 SRSF4 TGFB1I1 GNAI1 ATP6V1A MMP15 IRS2	down	***
GO_NEGATIVE_REGULATION_OF_CELL_PROJECTION_ORGANIZATION	0.0051079	0.0435543	0.4070179	-0.2741115	-1.415493	152	TNR DAB1 SEMA6B SEMA3G SEMA6A DENND5A RAPGEF2 FYN TBC1D7 RHOA SEMA6D ASAP1 SEMA3B PAQR3 PPP3CA SPRY2 WNT3A ZNF365 LRP4 PTPRO TRIM46 VIM PAFAH1B1 RUFY3 KREMEN1 SRGAP2C KANK1 MYLIP PSEN1 CTSZ BAG5 IFRD1 RTN4R TRAK2	down	*
MIR4719	0.0001714	0.0030184	0.5188481	-0.2409934	-1.415035	423	WEE1 AKAP5 TAL1 CPEB2 P2RY1 NUP54 RCOR1 ZBTB34 LONRF1 THAP2 FLVCR2 NR3C1 VAPA IL1RN OTUD4 MOB1B CD36 KIAA0355 PTPRM ADAM17 LIFR PPP1R15B CLEC7A GLS PRSS12 PPP2R2A NR4A1 MED26 TCF7L2 GPM6A CCNI RHOB ZMIZ1 UNC45B CWC22 RAB12 PTPN21 FOXO1 HNRNPA3 DENND6A PIP5K1B FAM76A REST TJP1 ZNF24 FBXL3 KIF26A CDKN1A EPGN CDS2 ZBTB43 PLEKHB2 PER1 MBD2 TBX5 RBM44 SPRYD7 BCLAF1 PDE1C IL24 CRIM1 NCKAP5 TANC1 CNOT6L NCOA1 FOXN3 LACC1 SPIN1 FRY METAP1 PHACTR2 MAGI2 PNMA2 GABPA ATP6V0B JUNB MTMR9 EEA1 HSPA13 IDS CREB1 LUZP2 ATL2 RC3H1 FSD1L OGFRL1 PALMD AGFG1 SPRY4 CDK17 HNRNPD SPOP AZIN1 GOLGA8R ABHD13 VAMP4 TSC22D1 PCDH17 PPP3R1 POLK FAM98B SMAD2 INO80D HACE1 PITPNA RBL2 NBN DCTN4 CYB5R4 DIXDC1 CREBBP KPNA4 GLUL RASSF8 RET TTC28 MARC1 DOCK10 FAM126B KIF1B CAMSAP2 SLC22A3 NABP1 C1orf115 SLC35A1 ZBTB44 SLC16A10 ABI1 REEP1 KLF15	down	**
GSE2706_2H_VS_8H_R848_STIM_DC_UP	0.0038951	0.0355427	0.4317077	-0.2702417	-1.414947	166	RBP4 ACP5 PECAM1 HVCN1 CCRL2 PRAM1 CDC42EP2 DPEP2 SGMS2 BTG2 AHRR ZNF503 ABCG1 ZNF697 NFE2L2 SPTBN1 SLC19A1 MAP2K3 LINC00528 KIAA0513 ZCCHC24 DENND3 PLBD1 PLEK PINK1 MAFF BACE1 HCAR3 TECR SGK1 CELF1 DUOX1 PTGER2 ADNP2 SIGLEC17P FOXO3 ICAM2 SORT1 TIMP2 TGFB1I1 PHF19 MFSD12 GEM ICAM1 ESYT1 CTSC P2RX1 CBX7 EGR1 CRTAP TREML1 DCUN1D3 TREM2 PLXDC2 PIGK PTGS1 QSOX1 FXYD5 ABHD14A	down	*
GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_DN	0.0040011	0.0362004	0.4070179	-0.2701677	-1.414559	166	WEE1 CLEC1B SLC31A2 ACP5 RAMP3 ZMYND15 LYVE1 PTPMT1 BAIAP2 SLC39A8 LAMP1 ITGA5 EIF4E LAIR1 MTHFR EFCAB14 MOAP1 EPOR RNFT1 DSE MRVI1 SNX3 CD80 SERPINB8 FAM189A2 AK1 REL EGLN2 CD164 MAPK8 TGIF1 IFNAR1 GALC TMEM107 CLASP2 SLC10A6 IST1 PRDM8 ICAM1 CTTNBP2NL LRP12 PARVA TMCC3 MT2A ENY2 ATF4 CSF2 HERPUD1 NAF1 MB21D2 MYH10 EYA3 MT1E CALR CD69 CYP51A1 UBE2N TRIM13	down	*
GO_RESPONSE_TO_LIPID	0.0000112	0.0003065	0.5933255	-0.2270524	-1.414522	720	SLC6A4 SMAD6 RBP4 CXCL3 SLPI ACP5 KMO ZNF366 RAMP3 IL1A SASH1 EDNRB SCIMP PPARG ADTRP CD55 GATA2 WFDC1 IL1B TIE1 CAT RAMP2 THBD PID1 INSIG1 ENG LPL LY86 RGS9 CAV1 FOSL1 CRY2 MYD88 ADCYAP1R1 TBXA2R C5AR1 FGF10 NR3C1 TGFBR3 IL1RN CBL SLC11A1 TGFBR2 TRIB1 CASP9 RHOA TXNIP BRINP3 CD36 ANXA1 MIR146A SSTR1 ATP2B1 CARD16 ADAM17 TNIP3 FZD4 LITAF ABCG1 FOXP1 EIF4E NR4A1 SIRPA RB1 TRAF6 SFRP1 WNT3A KANK2 HNRNPU PDE4D NODAL IL10 ROCK2 PTGIR FOXO1 CASP1 PTAFR KLF4 REST ID3 KLF9 DAB2 THBS1 ARNTL BCHE SOCS2 LY96 CCL3 NFKB1 CDKN1A NR1D2 KCNMB1 CXCL2 IRAK2 VIM SELP AXL TLR4 IGFBP2 LBH PER1 DUSP1 INHBA CPT1A MBD2 CYP26B1 IL24 ANXA3 NCOA1 TGFB2 GLB1 PIAS1 GNRH1 HCK PDK4 UFM1 WNT9A FAM107A CREBRF CD80 ADCY2 AREG IL6 RWDD1 AQP3 JUN DHH NOTCH1 ETS1 DDX17 CARD8 JUNB DNAJA1 PTGER4 CCR7 IRF8 DDX5 PRKCE CREB1 PTGER2 MALT1 MT-ND3 CXCL5 EGLN2 ACSL1 PLCG2 FOS ADNP2 PELI1 MAPK8 FOSB WNT11 DDX18 HNRNPD EPHA3 TGFB1 AKIRIN2 NR2C1 CD6 TGFB1I1 GNAI1 MMP15 IFNAR1 CD86 PIM1 PLSCR4 KLRC4-KLRK1 WBP2 CRY1 PLAA PDE4B TSPO RXRA SMAD2 JUND NR2E3 ICAM1 IL18 ABL2 TFPI ARRB2 OSR1 VPS4B TAB2 RIPK2 NLRP3 PTCH1 HAVCR2	down	***
MIR9985	0.0001023	0.0019718	0.5384341	-0.2346467	-1.414472	529	PRMT8 SLC24A4 RAB11FIP1 SEMA6A STAC MS4A7 ENDOU PPARG GATA2 SNX10 RAPGEF2 ST6GALNAC3 SIK1 CDH5 ARRDC4 ZBTB34 TMEM170B ST3GAL6 KIAA1109 LONRF1 QKI HMGCR DYRK1A KCNN3 NR3C1 TGFBR3 RGPD5 HEG1 ERG SEMA6D ATP2B1 HBEGF BEST1 LIFR ASAH1 ITGA5 BTG2 FZD4 LITAF CAMTA1 SLC7A11 ABHD6 GATA3 SFRP1 SPRY2 ITSN2 SOX7 SLC7A2 TAPT1 NRARP FOXO1 BNIP2 ZCCHC24 CDIP1 SSH1 MGAT4A PDE3B NPAS3 NR1D2 ARHGEF26 SHC4 SHE PTGER3 RNF139 PEAK1 KPNA3 RUFY3 NRBF2 FAM76B AKIRIN1 SNN ZNF426 BTG1 USP25 PDK4 TMEM9B CREBRF DCP1A SLC25A25 ID4 PDHX CCNY RYBP DNAJC27 PSEN1 RNF141 SLC9B1 NXF1 NECAP1 C2CD2 PSMA1 C20orf194 HIC1 C11orf58 BMP3 DDX5 GRB2 CREB1 KBTBD8 RC3H1 HSD17B12 TSPYL1 GFPT2 CELF2 AGFG1 POGLUT1 NIPAL4 NECAB1 FOXO3 SLC35F1 FOSB PKIA AKIRIN2 VAV3 PDS5B RSBN1L SBF2 SLC24A1 NPTN GATA6 KAT2B TMA7 PHLPP2 ATAD2B INO80D AMD1 GEM GLTP ABL2 CDC42EP3 TRAPPC8 PTCH1 VSIG10 MAP3K4 LYSMD3 MARC1 RNF38 SCAI EPB41L4A CECR2 TLK2 PRKG1 MMD PAIP2 NRP2 C1orf52 NABP1 LPAR6 GSPT1 SMAD4 MIER3 CACNA2D3 HSDL1 SPATA13 FCRL1 SLC16A10 UBE2V1 ACVR1C PLAG1	down	**
GO_ENDOSOME	0.0000087	0.0002479	0.5933255	-0.2266653	-1.414289	742	SLC6A4 RAB11FIP1 SLC31A2 MCOLN1 ACE GPR15 SGK3 OSBPL11 FGD5 OSBPL1A TMEM150B LHCGR SNX10 DCSTAMP PTP4A2 RAPGEF2 HSD17B6 RAB3C PCSK9 ARRDC4 FIG4 FOLR1 FYN SNX32 PLEKHF2 CAV1 CORO1C NEDD4L CALCRL MYD88 ADCYAP1R1 S1PR1 ARL8B CD1C LAMP1 CD22 SLC11A1 RFTN1 GGA2 RHOA NUMB ANXA1 SPG21 RRAGC MCTP1 RILP RAP1A CHMP1B ZDHHC2 PICALM LITAF ABCG1 CYB561A3 ABHD6 ADRB1 ADRB2 TRAF6 GRN LAMTOR3 WNT3A ZFYVE16 UBE2D3 TFRC RAB14 RHOB ARRB1 RAB12 DENND6A AOC3 ITM2B LEPROTL1 CDIP1 UHRF1BP1L MVB12B MYO1B GAPVD1 LY96 CTSD TMBIM1 IRAK2 AQP4 C9orf72 ATP6V0D2 TLR4 ARC M6PR SFTPD PLEKHB2 PRF1 EPS15 WDR48 HTT VAMP5 TM9SF2 FKBP15 HLA-DQA1 BACE1 CMTM6 PI4K2A RASGEF1B SIAH1 TBC1D5 SNX3 TMEM9B CD8B VAMP3 FLT1 WASF2 VPS37A GPR61 CTSS KIF13A PSEN1 IL2RB INPP5B APPL1 MAGI2 RAB8B PIKFYVE RAB31 SFTPB OSBPL9 ATP6V0B ATP11A VPS26A JAK1 TBC1D12 RAPGEF1 SNX2 STX7 EEA1 ACKR3 PI4K2B GRB2 RAB8A SNX1 GRIA1 TRAK2 UVRAG APH1B CLN3 CST7 OCIAD1 FGFR4 TMEM192 ATP6V0D1 UBB CD164 PTP4A1 EHD2 TRAPPC10 CD74 MME EPHA3 SORT1 EHD1 NIPA2 AP1G1 SFTPC CD1D VAMP4 ZFYVE9 SBF2 MTMR2 TMEM230 IFNAR1 PIK3C3 ATP6V0C ANKRD13A FCGRT STX12 VPS39 CLCN6 SYT11 UNC13D LDLRAD4 ARPC2 SLC31A1 CHMP3 ARRB2 PARM1 RAB5A ACAP2 TPT1 ATP9B CXCR4 VPS4B EPHA4 TAB2 GIMAP5	down	***
GSE3982_EOSINOPHIL_VS_BCELL_UP	0.0046325	0.0403875	0.4070179	-0.2708605	-1.413935	158	MCOLN1 COQ2 INPP5A PDE4C FUCA1 TGFBR2 TRIB1 ANXA1 SERINC1 EPM2AIP1 ADAMTSL4 RHOB FBXL5 ZMIZ1 ARRB1 SDCBP TPSG1 PTAFR KCNMB1 TLR4 CD302 PTGER3 DUSP1 SMAD7 ADIPOR2 SLC6A6 TLL1 HCK SEC14L1 NOTCH1 HK3 BMP3 FOXN2 PPP1R15A DAPK2 PSTPIP2 PTGER2 TNFRSF9 UBB ZNF669 MMP15 DOK2 CRY1 GLTP CHMP3 ACACB G3BP2 PKNOX2 PDE4A PTEN THEMIS2 GRB10 CREG1 CNR2 NR4A2 HIPK1 FUS AOAH ICOS FPR1 EFNB2 ADAMTSL3	down	*
GO_VACUOLE_ORGANIZATION	0.0059774	0.0487769	0.4070179	-0.2743687	-1.413842	144	FIG4 GNPTAB ARSB RAB33B CLN5 GRN TMEM41B RAB14 PPT1 GAA MAP1LC3B TPP1 UBQLN1 ATG7 C9orf72 PINK1 HEXB CLN8 SYNPO2 GABARAPL2 PSEN1 PIKFYVE TBC1D12 CLN3 RALB ATG3 TREX1 UBXN2A TFEB ATG2B SMCR8 PIK3C3 GABARAPL1 STX12 RAB5A PIP4K2A VPS4B TRAPPC8 ULK2 LYST FEZ1 FEZ2 AKTIP SH3GLB1 RB1CC1 CHMP4A RAB39A RAB1A TMEM165 CLVS1	down	*
MEISSNER_NPC_HCP_WITH_H3_UNMETHYLATED	0.0015786	0.0179290	0.4550599	0.2902545	1.413588	385	SLC9A3 PRR15 GPR156 SCIN ENTPD2 SLC5A5 MEX3A SLC13A3 CHST6 GALNT6 KBTBD12 PKP1 SLC25A21 ECE2 SLC26A8 ILDR1 IGFBP6 LYPD6B CD164L2 GRIN2A SP5 DLGAP1 MARVELD3 MOCOS INSRR P2RX2 PCDHGA11 AP1G2 MANSC1 KREMEN2 LTB4R2 LAMC2 CUL9 SPAG16 F2RL1 CBLC CYP24A1 MAP10 THBS4 HHAT ITGB4 P4HTM SYCP2 TTC22 DCDC2 HORMAD1 AP1M2 B3GNT3 ASS1 PROM2 SLC45A1 ABCB9 OXTR HSF4 GRHL2 PRRT3 AFAP1L2 KRT18 OSMR STK32A TNFRSF25 DMGDH TCF20 SPAG6 ARTN SLC44A3 WDR86 SEMA4F IRF6 ST14 FAH KY MAPK13 C9orf50 GRIN3B SPATA32 KRT19 LTBR TMEM30B DHTKD1 NAGS AGBL2 DDIT4L TUBG2 NRXN2 COL26A1 CHMP4C TFCP2L1 WNT10B MYO5C LRRC15 ODF3B SSH3 TMCO4 PARP14 IFITM10 PKDREJ CHRNA3 IL12RB2 CDCP1 MAB21L1 HTRA3 MSH4 SH3D21	up	*
GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN	0.0060545	0.0492959	0.4070179	-0.2665712	-1.412286	173	PECAM1 HVCN1 PLEKHF2 CALCRL GTF2I SLC39A8 PLEKHA1 CD22 NFATC3 ABCB1 KIAA0355 UBL3 FOXP1 SERPINB9 C1orf162 EPB41L2 ADARB1 TAPT1 SLC38A11 MYO1B LAPTM5 NFKB1 UBE2E2 HPSE UXS1 ALOX5AP BTG1 PRCP FLT1 SENP3 CCR7 OGFRL1 SNRK BLOC1S6 NIPAL4 ICAM2 HSF5 SAV1 VAV3 CHRAC1 APLP2 BMP2K SELPLG MOB3B SESN1 BLOC1S2 SEMA4A TBC1D1 ZNF471 MMD P2RX1 FCRL1 IRF2	down	*
GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN	0.0047584	0.0411156	0.4070179	-0.2712118	-1.412139	161	KLF13 GLIPR2 LRRC8C CLDND1 CTSW ST3GAL6 AQP9 ELF2 SFR1 B3GNT5 KLF6 PRSS12 CAV2 CST3 EVI2B PPT1 MAP1LC3B SELL ARAP3 UBE2B EPS15 GNAQ PIK3R5 HEXB AQP3 IFNGR1 UBAC2 GMFG GPRIN3 RUNX3 ICAM2 SPOP PPP2CB METTL14 ZC3H12D PLSCR4 KAT2B SERINC3 NR2E3 FKBP1A TAB2 CTSC LYST CNN2 USP48 SUGT1 CENPC LNPEP MZT1 ICOS SNW1 FXYD5 TES FAM78A AKAP13 RNF19B MYO1F ANKH CRLF3 CPNE3 INF2 DPP4 ZC2HC1A AIDA	down	*
GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP	0.0060545	0.0492959	0.4070179	-0.2665426	-1.412135	173	MSRA LILRB3 CD33 TACC1 LCP1 TOR1AIP1 TAPT1 GAA STK17B SELP ARHGAP9 SNORA28 PPP2R5C NRBF2 LMBRD1 TOPORS PRCP S1PR4 SLC8A1 RNF149 SNAP23 OASL GIMAP2 GLUD1 TYROBP JUNB RCAN1 SNX2 HERC1 IDS RC3H1 CST7 ACSL1 TIMP2 CHPT1 RELL1 PHF2 TSPO ARPC2 XKR8 DCTN4 DHRS12 MEGF9 SCPEP1 PLGRKT FAM126B AIM2 C21orf91 CNN2 EVI5 UBR2 RBMXL1 TMEM50A CX3CR1 S100A8 FAM8A1 NFAM1 RNF167 IFIT5 FAM160B1	down	*
RAY_TUMORIGENESIS_BY_ERBB2_CDC25A_DN	0.0017191	0.0190355	0.4550599	-0.2594361	-1.411931	224	RBP4 PHACTR1 FABP4 SMIM12 SAMHD1 CRY2 PRPF38A FUCA1 SCARF1 DDO TXNIP RRAGC CES1 MAPK8IP1 CST3 AGO4 CFD SCP2 PPM1K LIN7C AOC3 ITM2B FAM76A AFAP1L1 PER2 CDS2 IRAK2 ZBTB43 ZMPSTE24 PINK1 PRICKLE2 PEF1 BTG1 RBM39 CDC40 INPP5B NOTCH1 SH3BP5 LTBP2 RPS6KA1 CASZ1 EPC2 ACSL1 MBP DDHD2 TCF4 SRSF4 SMCR8 ZFYVE9 CPT2 TOB1 SERINC3 RXRA ELOVL1 CDC42EP3 TAB2 TOB2 SP100 EPHA2 TRAF1 SKI PUM1 USP48 ZBTB40 CBX7 HERPUD1 PHYH KLF15 GGT6 C5AR2 ZBTB8OS HP1BP3 HEY1 MUL1 DNAJC8 C11orf54 GABPB1 RPA2 SLC23A2 DUOXA1	down	*
ZNF784_TARGET_GENES	0.0013022	0.0156063	0.4550599	0.2871286	1.411576	442	LYSMD1 BUB1B NUP107 C17orf75 PGM2L1 DDIT4 THEM4 TTC26 PLK1 NUF2 WDR70 ZNF221 CIB1 AGK NME1 AARS2 TOP3B TJP3 TMEM41A ZNF391 BBS1 RNF216P1 PAFAH1B3 CCDC77 NUP155 CBX3 PSENEN GTPBP3 COASY ABCC5 RBM28 TARS2 EME2 THAP10 GEMIN7 SPAG8 PML MNAT1 ZCRB1 DDX51 SUPT5H ANAPC5 ING4 HDGF SSBP1 STX18 MCAT WDR31 DHX33 ENPP3 ZNF775 TMEM79 RNF207 KLHL22 WDR24 CAPS2 SMG5 ZNF233 GALK2 PCAT6 MRPS34 HIRA COPS7B STOML1 CASP7 JMJD4 MLEC MTND5P11 STX18-AS1 NDUFA13 GFM2 ZNF282 SIL1 FAM207A PRRG2 ZBTB45 NIF3L1 PROX1 EFCAB7 LSG1 RAI1 PPHLN1 VPS25 SIRT4 DUS1L ASCC1 MRPS23 PPP6R1 WDR83 NSUN6 NOSIP NOC4L KPTN NMNAT1 SNAP47 GINS3 NDUFS7 YIPF2 DDX55 PRMT5 ZNF580 MICAL3 NME1-NME2 TSPAN10 RBM42 BANF1 ELFN2 POLR3B SCNM1 CDK5RAP1 BMS1 TRIP4 ZFP14 PPFIA3 PFKM MARK4 GTF3C5 SRP9 VPS9D1 AGBL5 TMEM101 AURKAIP1 ZNF131 DNAJC10 TP53 BPNT1 TBL3 PIGL FAM185A MRPL48 ATF7IP ZER1 TRUB2 DDX41 MZF1 SETD5 SLC33A1 HEXIM2 ANO8 MRPS16 ASB16-AS1 MAN2C1 TMEM259 RPL36 NOXA1 ZNF276 ZNF688 ZNF579 PRPSAP2 NSL1 EDC4 SNHG17 MCEE SLC4A1AP RAG1 TEFM	up	*
GO_ORGANELLE_INNER_MEMBRANE	0.0016671	0.0186286	0.4550599	0.2880745	1.411373	420	CPS1 BDH1 COA1 CHCHD6 SLC25A21 THEM4 MRPL46 NDUFS6 ACAD9 ALDH18A1 SFXN1 NNT TYMS COX6B2 SHMT2 P2RX2 MRPS35 COQ3 COX11 AGK UQCC1 TAMM41 FAM169A NDUFB8 SDHA DPY19L2P2 MRPL15 DPY19L1 CBX3 NDUFS2 TMEM177 GCAT ERAL1 MRPL3 MRPL27 LMNB1 SLC25A39 TIMM50 MRPS11 FDXR MRPS30 MTG1 PHB SLC25A10 UQCR11 COQ9 MRPL36 MRPL37 GOT2 SUN1 TRAP1 L2HGDH MRPS2 SLC25A13 MRPL17 MRPS12 TMEM120B ATAD3A UQCC2 CHCHD3 UQCRFS1 NDUFA11 SPG7 COA3 FOXRED1 LMNB2 SLC25A18 MRPS34 DHODH MRPL11 MRPL52 COX7C PPOX MRPL4 DAP3 DNAJC11 NDUFA13 COX10 TIMM13 STOML2 CHCHD1 SIRT4 MRPS23 BCL2L1 MRPL24 MRPS33 CKMT2 MRPL28 MRPL41 ROMO1 SIRT5 DPY19L2 MRPL53 PRODH NDUFS7 MRPL51 SPAG4 NDUFV1 MRPL14 SCO2 MRPS25 MRPL55 NME4 UQCRC1 COX5B SLC25A29 MCU MRPL9 MRPL21 MICU1 NDUFA8 NDUFS8 CPOX AURKAIP1 UQCRQ TIMM44 LEMD2 MRPS27 SIGMAR1 SFXN4 MRPL20 MRPL48 NDUFB7 COX6B1 MRPS26 IMMP2L TMEM201 CYP11A1 MTG2 NDUFAF6 MRPS16 UCP3 SPHK2 DPY19L3 MRPL12 CRAT PARL MRPL43 OPA1 RSAD2 MRPL2 TOMM40 TIMM10 COQ5 MRPS6 NDUFB2 SMAD3 LRPPRC COX15 TIMM9 COX6A1 SLC25A35 COQ4 NDUFA4L2 COX6C ABCB8 NDUFA9 SDHC SLC27A1 WDR93 MRPS7 MRPL35 SMAD1 MRPL13 GATM MRPL33 NDUFA10 PET100 LEMD3 COX16 SRC PSEN2 NDUFB10 TIMM23 IMMP1L NDUFS4 ERN1 CYP2E1 PLA2G4B	up	*
GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN	0.0060545	0.0492959	0.4070179	-0.2663492	-1.411110	173	SMAD6 EPAS1 SLC12A6 KLF13 HHEX TRPV2 HSD17B11 CTSW LAMP1 CBL PDE2A GM2A ABCG2 IFI30 CYB561A3 EVI2B ITPRIP PTPRO LEPROTL1 ID3 STK17B SPAG9 PDE3B PTPRC HPSE ELMSAN1 CPT1A AFF1 ADD1 TMEM9B CREBRF WASF2 ETS1 OSBPL9 IFNGR1 AP3B1 CD74 HBP1 ANKRD13A SERINC3 HELZ BMP2K CCR6 CALHM2 CDC42EP3 SPIB CNN2 ARHGEF18 CDKN1B ICOS PLEKHA2 FAM53B RNF167 PIK3CG MICAL1 HLA-DRB1 MAP4K2 RCSD1 FCRLA	down	*
HLF_01	0.0053812	0.0451484	0.4070179	-0.2621674	-1.410859	197	SECISBP2L CALCRL AQP9 CTDSP1 CDC42 FBXO3 SEMA6D EIF4A1 SH2B3 FOXA2 ZDHHC2 ZBTB21 FOXP1 ADRB2 WNT3A PDE4D AGO3 HNRNPA3 KLF9 USP2 TNFSF15 RMDN3 CLIC4 DPH3 CADM1 UBE2E2 GPR85 ELMSAN1 CRIM1 NCKAP5 CNTF OXNAD1 RHOBTB2 PIK3R1 DDX5 MBNL2 PREX2 DENND4A CELF2 SPRY4 CALM1 TNFSF13 FOXO3 TREX1 TFEB ZFYVE9 TSC22D1 ATXN1 COL15A1 TOB1 SYT11 EPN2 SPIB SREBF2 PKNOX2 CTSC ZDHHC5 PRKG1 RORA CACNA2D3 DNAJA2 HNRNPH1 FNBP1 MAP4 HERPUD1 PLAG1 AKTIP ING1	down	*
TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_DN	0.0057520	0.0474211	0.4070179	-0.2681813	-1.410573	164	CD52 CD55 GATA2 FCER1A IL1RN CD36 CD33 RNF125 HDC ANPEP SPI1 PTPN12 FUT7 CEBPA ABCC4 GMPR LAPTM5 ID2 IGFBP2 ALOX5AP IL7R TRGC2 AQP3 CD48 TYROBP ARHGEF10 CSTA CCR7 IRF8 GPR183 RPS6KA1 RASSF2 CST7 ACSL1 TNFSF13 MBP RUNX3 NKG7 XYLT1 BIN2 FPR2 TSC22D1 PDLIM1 CBFA2T3 DOK2 JUND SELPLG LDLRAD4 LAT CXCR4 S100A4 TIMP3 CCND3 EHD3 SETX CSF2RB ZBTB16 SH3BGRL3 ITGAL KBTBD11	down	*
REACTOME_HEMOSTASIS	0.0000861	0.0017028	0.5384341	-0.2329305	-1.410058	532	ANGPT4 WEE1 CLEC1B TEK OLR1 PECAM1 GATA2 SPN CLEC3B PRKG2 F2RL3 P2RY1 TUBB1 THBD RCOR1 TRPC3 FYN MMRN1 CD44 PDE1B CTSW CAV1 ESAM IGKV1-33 TBXA2R PRKAR1A CDC42 CD9 GAS6 FGR RHOA PDE2A CD36 ATP2B1 SH2B3 IGKV2-28 SLC7A7 RAPGEF4 RAP1A GNGT2 ITGA5 ANXA5 SLC7A11 ABHD6 GATA3 JAM3 GNG7 SIRPA CRK SRGN PDGFA TUBB6 CD58 RHOB KIF1C CFD ARRB1 PTGIR DGKE KCNMA1 PLAUR SLC7A8 THBS1 MAFG MPL KIF26A FAM49B ABCC4 ITPK1 DOCK9 ITGAX KCNMB1 SELL SELP JAM2 CAPZA2 FCER1G PLEK PPP2R5C PPP2R5A GNAQ PIK3R5 GNAI2 MAFF MRVI1 VWF TGFB2 PROCR PRCP IGLV2-11 SLC8A1 PPP2CA PHACTR2 CABLES1 CYB5R1 SERPINB8 CD48 PDE5A RAC2 TREM1 RHOG PIK3R1 GYPC PRKCE GRB2 SERPINB6 CAP1 PRKACA DOCK8 YWHAZ TNFRSF10B TAGLN2 IGKV3-20 PLCG2 SLC3A2 CALM1 EHD2 PRKCG DGKG CD74 DAGLA PPP2CB STXBP3 TGFB1 EHD1 VAV3 TMX3 VPREB3 CDC37L1 GNAI1 GNG5 SLC8A3 GNB4 APLP2 DOK2 IGHV3-23 ORM2 GATA6 GNA13 ACTN2	down	**
GO_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY	0.0000474	0.0010346	0.5573322	-0.2326654	-1.410046	573	FFAR4 CXCL3 HCRTR1 GPR17 EREG RAMP3 AKAP5 FCN1 CXCL16 GPR15 EDNRB PPARG F2RL3 LHCGR ADCY9 P2RY1 GPR65 ADCY4 RAPGEF2 RAMP2 PDE1B HCAR2 CCL3L1 NXPH3 RGS9 CCRL2 INPP5K CAV1 CALCRL ADRA1D ADCYAP1R1 TBXA2R C5AR1 S1PR1 P2RY13 RXFP1 MARCO PDE4C PDCL RHOA PDE2A ANXA1 SSTR1 ADA RAPGEF4 RASGRP4 GNGT2 FZD4 NMUR1 ABHD6 ADRB1 GNG7 ADRB2 ARHGEF2 GPBAR1 PDE4D RHOB GPR4 TAPT1 ROCK2 ARRB1 PTGIR CCL22 DGKE TACR2 PTAFR PRKD3 ROCK1 GRK5 NPR3 PDE8A CCL3 PDE3B P2RY2 GPR85 CXCL2 ARHGEF26 CCL4 PTGER3 XCL2 PLEK GNAQ GPR157 PIK3R5 GNAI2 CALM2 PTH1R GNRH1 S1PR4 HCAR3 METAP1 ADCY2 AREG WASF2 GPR61 PDE6A PDE6B RGS18 TAS1R1 HRH1 ADRA1A RAC2 GPR141 PALM PTGER4 CCR7 PIK3R1 ACKR3 GPR183 PTGER2 NPR1 HOMER1 SUCNR1 CXCL5 PREX2 OGFRL1 RGS13 GPRC5A TPRA1 GPR37L1 GPR3 CALM1 DGKG DAGLA CCR4 SORT1 VAV3 GLRA3 FPR2 NLRP6 GNAI1 GNG5 GPR84 APLP2 GLRA1 MRGPRF CCR1 CRY1 GNA13 ACTN2 OR52B6 RGS2 GPR18 GRK4 PDE4B QRFP CCL20 CCR6	down	**
GSE21774_CD62L_POS_CD56_DIM_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP	0.0034120	0.0322721	0.4317077	-0.2663676	-1.409702	172	PRX KANK3 CALCRL INPP5A C8orf58 CASP12 NCF2 PEAR1 ENTPD1 ABCG1 CLN5 ABHD6 DACH1 IL18R1 PPP1R13B KANK2 TFEC HERC3 TUBB6 SORBS3 CCNI CSRNP1 PRDM16 EXOC3L2 PPM1K PDE8A PTPRC TLR4 ALOX5AP ELK3 INSL6 RASGEF1B HEXB APPL1 RGS18 STAT4 SH3BP5 ETS1 BTD ELOVL7 RNF24 RASSF2 PANK2	down	*
GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP	0.0037481	0.0345709	0.4317077	-0.2650966	-1.409653	176	SIK1 ZBTB34 IBA57 PAFAH1B2 ZBTB2 EDEM1 SH2B3 DNAJC3 HBEGF SLC36A4 TACC1 SDE2 CRK LRRC57 ADO KLF11 MAFG ITGAX KCTD20 RNF139 SMAD7 PIK3R5 SNN SERTAD2 BTBD18 PPIL4 GZF1 SAR1A FOXP1-IT1 NXF1 NECAP1 ATXN1L CD83 GRB2 NUDT15 RUNX3 NAPG ABHD13 MAP3K2 PPP3R1 STON1 WBP2 PLA2G15 PITPNA GLTP CCDC69 TMEM184B NEK3 DAZAP2 MAPKAP1 PURB GRPEL1 CFL2 NR4A2 USP30 ANKS1A XPO7 FAM160B1 NFIL3 MEF2D FASTKD5 FCHSD2 METRNL GPATCH2L SLC25A28	down	*
GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN	0.0061611	0.0499733	0.4070179	-0.2659329	-1.409588	181	WEE1 FAM167A IL17RB TSPAN4 FGD5 TMEM126A LPXN TRPV2 ENG EGR2 CTSW CCRL2 RTN3 MSRA GNPTAB TLCD2 PFDN1 DNAJC18 RAP1A LITAF RGCC IL18R1 SRGN FABP5 TLE4 YBX3 PXDC1 MAFG UBE2E2 ID2 KLRD1 VAMP5 RABGGTB TDRD7 HGSNAT RNF149 CD160 PSEN1 KCTD12 PLK3 IPO7 TCP1 CST7 SLC3A2 RUNX3 NKG7	down	*
MIR889_3P	0.0023503	0.0242132	0.4317077	-0.2630928	-1.409426	192	SMAD6 EREG AKAP5 ABHD5 PPARG ZC3H12C CPEB2 STXBP6 CITED2 CD1C WBP4 ZEB2 SDE2 ECHDC1 EPM2AIP1 PER3 LIN7C ADO TNFSF12 BRF2 CUL5 CYP26B1 CDKN2AIP LIN7A MCMBP BCAR3 HECA TMTC1 LRCH1 SLC14A1 CNTN4 WTAP PI4K2B CREB1 PDZD2 CXCL5 OGFRL1 HSF5 TMX3 PDE12 SLC24A1 TOB1 RIMKLB ACYP2 RNF2 MEX3C PLGRKT SCAI PTEN MMD CAMSAP2 RORA IAH1 MAPKAP1 TLK1 EVI5 ABI1 GJC1 CENPC CLOCK	down	*
GO_CELL_CYCLE	0.0000002	0.0000103	0.6901325	0.2732469	1.409386	1523	HMGA2 CCNO PKHD1 MCIDAS TRIP13 DDX11 FOXM1 CEP72 SPICE1 BRINP1 HELLS KIF20A MDM1 DDX12P HJURP STAG3L2 CUZD1 RUVBL1 CDC45 TICRR MCM10 FANCI CHEK2 BUB1B NEK2 TRNP1 CCNB1 SOX2 CENPF TIMELESS PAGR1 PDCD2L STOX1 MND1 PBK KIF18B NDC80 PRIM2 TBRG4 BRCA1 PHGDH TUBB2B TTK GINS1 CDCA2 CDK4 SMPD3 RACGAP1 IQGAP3 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN SLC26A8 POLE CNTD2 ASPM NABP2 STIL MSTO1 CEP70 PLK1 NUF2 YEATS4 CDCA8 AURKB CENPA PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 E2F3 TFDP2 CCNB2 FIGNL1 RBBP8 UHRF1 MCM4 PRKCA CYP27B1 MCM2 RAD54B TYMS CDC25A MYBL2 PRC1 XRCC2 ORC1 NOX5 CCNF DTL CIB1 TDRKH MCM8 LIG3 MIS18A MAP2K6 ZFYVE19 NCAPD2 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 LMLN HAUS5 RANBP1 CEP250 WDR62 RSPH1 CASP2 MELK HMMR BTRC SMARCD3 EXO1 DLG1 NLE1 KIF23 CEP55 STAG3 CHAF1A FOXA1 MKI67 CUL9 BOD1 CUL7 KIF15 TP53BP1 FBXO43 KNTC1 RHNO1 KIF3B BUB1 FANCA LGMN MSX2 AUNIP TOP2A MAP10 GPER1 AURKA EME1 CBX3 REC8 ODF2 POLA2 SYCP2 ATR POLD2 SFI1 TPR KIF2C MCM7 MAD1L1 E2F2 MSX1 CD2AP CENPW POC1A CLSPN CXCR5 IL12B RRM2 TTLL12 CDCA5 PRKDC WDHD1 FSD1 NSUN2 RAD54L TOM1L1 KIF11 FANCD2 GPSM2 MCM3 CHAF1B HORMAD1 CDC25C SOX4 TGM1 EGFR LIG1 EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 ORC6 MAD2L1 PSMD4 SOX11 MDM2 SPC24 AKT2 DSCC1 MGA PKMYT1 BRIP1 FBXL8 SPAG8 BLM PPP5C PML C2CD3 CNOT3 ERCC2 MNAT1 STXBP4 SPRY1 PARD3 SLC39A5 SKP2 RECQL5 PES1 PSRC1 PTPN3 INCENP KNSTRN CKS1B TTBK1 NCAPG2 AFAP1L2 CDKN2C NUSAP1 CBX5 KRT18 ANAPC5 ING4 CTDSP2 CDK1 CROCC CDK12 POLE2 CEP97 CENPJ RFWD3 BIRC5 KIAA0753 GMNN SUN1 DIS3L2 POC5 E2F1 NCAPG PSMB5 CCNJL TMEM8B DNA2 KIF2A STEAP3 ANAPC7 FEN1 SSX2IP EZH2 CNOT11 SPAG5 EGF TAF6 METTL3 RAB11FIP4 SAPCD2 TRAPPC12 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 ACVR1B FGFR1OP STK11 IRF6 KPNB1 GIPC1 MYO19 ANKK1 CEP63 INTS7 CCNE1 CEP192 RHOC CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 MTOR NINL TACC3 MNS1 RAD9A LLGL2 TUBB2A PSME2 KIF22 HIRA MAPK13 RAD51D MTA3 TRIM37 FBXO4 TUBA8 CHTF18 MYBBP1A CENPQ AKAP8L URGCP ESCO2 GAS2 FZR1 PKP4 NUDT16 CGREF1 CLTA KIF20B LAMTOR2 LIN37 SMIM22 TRIM32 ASNS SGSM3 ANAPC1 SND1 CDK13 POLD1 PSMD2 JTB ATAD5 PPME1 SLX4 CABLES2 CDC7 RAD50 ANKRD31 CENPK PROX1 SASS6 KLHDC3 SH2B1 TADA3 STAG3L4 CENPV MEI1 CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B ROPN1B TUBG2 AAAS GBF1 EFHC1 ALKBH4 BCL2L1 RPA1 CHMP4C PELO WNT10B FANCM CDK5RAP2 MCM6 DNMT3A CHTF8 BLCAP THOC5 STAMBP MRPL41 CENPT PRMT1 CKAP2 SRPK2	up	***
GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP	0.0057060	0.0471629	0.4070179	-0.2678367	-1.409300	168	OSBPL11 FABP4 THBD AATK BACH1 MYD88 VAPA SLC11A1 CIT KCNK3 MAP3K8 HLX PAG1 FBXO8 HNRNPA3 ZFAND5 FAM49B PDE8A ERP44 SELP CCL4 GNAQ TANC1 CMTM6 PROCR BTG1 RNF149 IL6 PSEN1 SOCS3 IL2RB CTSZ JUNB MTMR9 RCAN1 PPP1R15A PTGER4 NAA30 TUBGCP3 AGFG1 GNAI1 CD86 PDCD1 ORC2 MEIS1 RGS2 IST1 BMP2K FKBP1A CEBPD CYB5R4	down	*
PASINI_SUZ12_TARGETS_DN	0.0007172	0.0098218	0.4772708	-0.2548855	-1.409138	277	MEG8 GLIPR2 WNT4 DPYSL2 LRRFIP1 BMP2 BDNF DDX6 CAV1 CORO1C MYADM RTN3 CITED2 IDI1 TRIB1 ANXA1 BMP1 HBEGF MALAT1 CSRP1 BTG2 ANXA5 FOXP1 KLF6 CAV2 SERPINB9 TMEM123 TUBB6 CNN1 RHOB PTPN12 AMOTL1 AHNAK NPNT BNIP2 THBS1 KLF7 TMBIM1 CDKN1A RBMS1 VIM AXL ID2 ARAP3 DUSP1 ANXA3 TGFB2 MTPN MYO1C JUN VAT1 LIMD1 ETS1 SKIL CAP1 GPRC5A CD151 SLC25A24 PKIA FLNC TIMP2 PEA15 KCTD10 TGFB1I1 IRS2 TAGLN SYT11 PDLIM5 YAF2 ELOVL1 IER5 SOAT1 KPNA4 PARVA SYNPO2L TMCC3 GRB10 EID1 CNN2 SPSB1 GHR CFL2 DUSP6 TMEM30A TMEM43 MYH10 ITGB1 SH3GLB1 ZYX	down	**
CEBPZ_TARGET_GENES	0.0000021	0.0000736	0.6272567	0.2741321	1.407889	1249	ONECUT2 MDM1 RUVBL1 CEP89 TICRR FANCI ZNF273 TROAP NUP107 DROSHA POLQ GGCT TTF2 IFI27L1 RGMB-AS1 BRCA1 CREB3L4 ZNF138 MRPL46 CDCA2 AGFG2 ANKZF1 TRAIP NABP2 FLAD1 TTC26 SAP30L-AS1 DGCR8 NUF2 IFT27 CDCA8 CENPA ACOT8 GOLGB1 CDC25A UMPS PMS2 CCNF TDRKH MIS18A LIPE-AS1 DZANK1 CDK5RAP3 LRRC27 TRIM45 LSM5 ZNF726 FAM220A NME1 GOLPH3L TOP3B C5orf34 RUVBL2 TMEM41A NEURL2 RAB11B-AS1 OSBPL2 CHAF1A DCBLD2 HLTF EMC9 TP53BP1 POLM COPG2 TOP2A AURKA IQCD ZNF587B ITGB4 ATR POLD2 GTPBP3 ZNF174 RSRC1 C14orf93 TPCN1 RBM28 BRPF3 RAD54L MRPL3 FANCD2 MCM3 CDC25C AIMP2 EMG1 PYCR2 TARS2 RNFT2 WDR60 CHD6 SARS2 ZNF443 MORC2 C7orf50 ORC6 ACTL6A CKAP2L TRMT61B COX19 DCTPP1 DNAAF3 ANKRD16 SPC24 MRPS11 B4GALT7 BRIP1 RAD18 SNAPC4 BLM LRRC45 CNOT3 ARL16 ERCC2 RECQL5 DDX56 INCENP CKS1B ISOC2 FRMD5 CBX5 ASF1B MRPL37 ANAPC5 PABPN1 HDGF SSBP1 CCDC61 KCTD7 MDH1B RFWD3 ZNF652 AP3D1 NUDT2 ANKRD54 TYW1 POLR3K E2F1 UNG STX18 VPS28 ZNF419 MCAT PMEL BPGM FAM98C ENPP3 ZNF584 NARF DPH7 TSPAN31 ZNF775 COA4 MRPS12 LCA5 FAM102A DIAPH3 VPS72 MAST1 WDR24 SEMA4F ZNF324B STK11 KPNB1 ANKRD39 CHCHD3 CHCHD2 SNRNP25 VBP1 GOLGA3 ZNF687 ZNF354A UBFD1 EDEM3 DPP3 CDC23 DLGAP5 ATP7B PDCD11 WDR53 NDUFA11 SPG7 SLC26A2 PSMA5 TRMU MTOR SNRPA TRIM9 FHIT DHODH KIF22 HIRA CCDC130 ROGDI DNM1 COPS7B DPH2 ZNF417 CENPQ AKAP8L LMTK2 TP53TG1 OS9 CCDC146 GINS2 MRPL4 ANP32E NUDT16 ITFG2 TCEA1 STX18-AS1 LIN37 ZSWIM3 ZSWIM1 DNAJC11 CCDC51 SND1 FAM207A CCDC159 ZNF416 AAMP NAIF1 ELAC2 CCT7 CCDC137 KDM3A CENPK BAZ2A RNF187 CPSF4 PWWP2A PSMB3 ORMDL2 PALB2 CENPM STOML2 ZCCHC17 GBF1 AP3M2 FAHD1 MRPS23 BCL2L1 UBXN6 NOL6 CDR2 ABCA7 MCM6 ARVCF KDM4B MRPL28 PRMT1 XRCC4 NOB1 MCM5 HIBADH GNG4 NMNAT1 ZRANB3 C5orf22 FAM161A ZNF563 RAB3D C1orf109 ZNF599 GINS3 LRCH4 ZSCAN32 NDUFS7 KATNB1 DOLPP1 POLR2I YIPF2 CREB3L2 RGMB CCNG1 PDIA4 IGHMBP2 SLC1A5 AP4B1 DDX55 GOSR2 TSR1 CEP152 TCERG1 MST1P2 COPZ1 DUS2 SPSB3 ARFGAP1 ZNF837 CEP85 ZNF519 NME1-NME2 GLO1 ATP6AP1 TSPAN10 CYTH2 CCNA2 RBM42 PRR11 BANF1 MANBAL HEATR5A SNRPD2 ANAPC2 TXNL4B PDAP1 CDK5RAP1 CEP164 PRPF31 NUBP2 BMS1 ARL17B TRIP4 MAP3K9 NBR1 SEC13 MCU MROH1 MLLT1 GTF3C5 SAMD4B SRP9 MRPL21 IKZF4 LLGL1 NDUFS8 TBCB ALKBH6 GNA12 ENTPD7 BCAS3 PNKP TARBP2 MAPK8IP3 ZNF91 TCF3 GNE DNAJC14 ADRM1 EARS2 RHPN1 ZMAT2 NDOR1 ALG1 HGS TIMM44 SNRPC PPIA TBL3 UBE2C LINC00205 TTC9C RHPN1-AS1 FBXO45 CDKAL1 SFXN5 DCAF11 ENO1 ZSCAN20 TMEM38A TPRN SLC39A1 PLIN3 WIPI1 ZNF367 TTLL5 CLASP1 FAM222B WIZ ATG4B CALU DDX41 MZF1 C12orf10 MSANTD4 TRAPPC6A SETD5 ANKRD11 CYB5B RPUSD3 CSTF1 CYHR1 COPE DNAL4 EIF2D RCN2 POLRMT PDXP MED16 MRPS16 ASB16-AS1 MAP3K12 MAN2C1 HRAS RAB40C TRAFD1 EIF2B1 COMTD1 CDK11B ADSL ZC3HC1 TBC1D10B PPP2R5E PNPO KHDRBS2 PSMB10 LCMT1 CYB5RL ABHD2 SDHAF1 FAM111B NFE2L1 TMEM9 TOMM40 SLC2A8 ZNF774 MCEE SLC4A1AP TRAF7 GLRX5 ZNF77 ARHGEF19 TYK2 CHD8 MPZL1 MTMR4 DCLRE1B TEFM URB2 ARMC6 MTR HOMEZ RPLP0 TMEM167A ZNF772 ZNF805 HINT2 SHKBP1 CS AP2A1 RMI1 HNRNPAB MTF2 THAP4 FAM149B1 PSMD3 PPP2R1A ZNF17 DHX38 SWSAP1 EVI5L NUP214 ELMO2 SAP30L GARNL3 KLF5 BBS12 DDX49 MAEA SCAND2P RAB4B ZNF691 CTPS1 IPO4 DRAP1 LAMTOR4 RMI2 SNHG10 DCTN3 TANGO2 TMEM203 IK HNRNPA1 SKA2 ABCB8 WDR12	up	***
GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP	0.0053789	0.0451438	0.4070179	-0.2672622	-1.407270	170	SNX10 SLC6A12 CDH5 FYN LPL BCL2A1 OTUD4 UBL3 PPP1R15B EIF5 BTG3 SGCA BAG1 PRKD3 CLIC4 RBMS1 ATF3 M6PR CLK4 MBD2 DSTN RAP1GDS1 DEGS1 PLAC9 USO1 EEA1 CD83 THUMPD1 ATP13A3 TCP1 AGFG1 KLF2 CD164 AZI2 DCK TEC RELL1 DOK2 ACADL ACYP2 PLAA MBNL1 GPX3 ARPC2 RTN4 HNRNPK TRAF1 FNBP4 KIT PSMD6 MT2A IQGAP1 DNAJA2	down	*
GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY	0.0018718	0.0203206	0.4550599	-0.2589311	-1.406664	215	RASIP1 HHEX IL1B FABP4 INPP5K CAV1 CORO1C HMGCR PRKAR1A CBL TRIB1 HEG1 SH2B3 DNAJC3 FBXO7 FOXA2 LATS2 HSPB1 HIPK3 PAQR3 RB1 SFRP1 SPRY2 HNRNPU MAPK8IP1 ADARB1 ITPRIP DUSP3 CEBPA SOCS5 CDKN1A PTPRC MIR24-2 DUSP1 PPP2R5A GNAQ UBASH3B PKIG PPP2CA PSEN1 SOCS3 SH3BP5 DNAJA1 DUSP8 IPO7 GMFG GPRC5A PPM1F SPRY4 PKIA CHORDC1 SMCR8 DUSP5 IRS2 MYOCD RGS2 KAT2B DBNDD2 PP2D1 CDKN1C IPO5 ADORA2A PAK2 PTEN DUSP7	down	*
GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP	0.0059458	0.0485953	0.4070179	-0.2642469	-1.406361	177	TMEM126A TRPV2 INSIG1 LPL LY86 CCDC88A BMPR2 TET2 IGSF6 METTL23 ABCG2 ITGA5 FZD4 SLC25A37 AKT3 SAP30BP NOSTRIN STX3 NR1D2 TLR4 TM6SF1 CD300C IL7R TMEM9B COPS2 DCTN6 OASL RWDD1 GLUD1 OSM HSD17B12 RNF24 NAA30 DENND4A ZCCHC9 TMEM192 RBKS BTBD7 PARD6A ZBTB11-AS1 LGALS3 IST1 CCNH TNFSF9 PAIP2 GRPEL1 SLC35A1 SNRPG FKBP1B CLOCK DRAM2 CBR4 DNAJB4 LAMTOR5 WAC TSC22D2 CAPZA1 MAP3K1 TAF1D FNIP1 MRPL16 PEX13 METRNL BTBD1	down	*
GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP	0.0051738	0.0439546	0.4070179	-0.2644403	-1.406023	175	SC5D LPIN2 ADPRH TMEM170B CD44 LONRF1 AKAP7 BCL2A1 ADAM17 CYB5A ZDHHC2 HSPB1 CYP4V2 IL10 MAP2K3 FABP5 STAT5A ST3GAL2 ITM2B KLF9 SSH1 HOPX RECK ELK3 MATK VAMP5 MYO1C PHACTR2 NEK7 RAB8B CD48 OSTM1 IFNGR1 COBLL1 HOMER1 NDST1 AGFG1 RIN2 CCR4 SAV1 TGIF1 IFNAR1 PIM1 CD81 STON1 GEM SESN1 IL18 MIER1	down	*
CEBPDELTA_Q6	0.0058680	0.0481142	0.4070179	-0.2642227	-1.405288	184	GPD1 DAB1 ACE FABP4 BDNF PDE1B CITED2 CDC42 IL1RN TRIB1 IL23A CCNL1 ZEB2 SEMA6D FOXA2 ITGA5 FOXP1 SLC7A11 NR4A1 LHX6 FLI1 MAP2K3 PTGIR ZNF423 ZADH2 UBE2E2 GPR85 ATF3 CCND2 ELMSAN1 RBM39 VAMP3 COPS2 C2CD2 JUN MITF NOTCH1 PIK3R1 MBNL2 OSM FOS FOXO3 FOSB TSHZ3 DOK3 ZFYVE9 MBNL1 PRDM8 SYT11 UNC13D SPIB ARIH1 PTCH1 SREBF2 TIMP3 PTEN RORA	down	*
GOLDRATH_ANTIGEN_RESPONSE	0.0031595	0.0303325	0.4317077	0.2943174	1.404325	306	TRIP13 KIF20A CDC45 MCM10 NEK2 CCNB1 UBE2T PRIM2 BRCA1 TTK RACGAP1 IQGAP3 E2F8 GTSE1 ANLN ASPM PLK1 CDCA8 AURKB CENPA ECT2 CDC6 GAPDH CCNB2 FIGNL1 MCM4 TYMS PRC1 CCNF HBB DTL LILRB4 SPDL1 CISD1 CHAF1A MKI67 BUB1 TOP2A AURKA KIF2C RRM2 CDCA5 GCAT SERPINA3 KIF11 MCM3 LMNB1 CDC25C LIG1 CD24 TOPBP1 CHEK1 MAD2L1 RAD51AP1 PERP GNPDA1 INCENP CKS1B CDKN2C NUSAP1 CBX5 ASF1B CDK1 BIRC5 GMNN POLR3K IGHG1 DNA2 FEN1 SSX2IP EZH2 ETFB	up	*
P53_DN.V1_DN	0.0051575	0.0438746	0.4070179	-0.2696836	-1.404182	161	AJAP1 ACP5 HMOX1 GREB1 CYP27A1 SLC16A4 THBD ST3GAL6 FXYD2 MAL BCL2A1 EPB41L3 PPM1D PTPRM ADA BTG2 GLS STOM NR4A1 ZFYVE16 SRGN APOC1 FABP5 CASP1 CPVL BCHE LY96 CDKN1A VIM IGFBP2 MATK NINJ1 KANK1 SGK1 SOCS3 IL2RB MITF STAT4 CTSZ ARHGEF10	down	*
GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS	0.0004708	0.0069971	0.4984931	-0.2444639	-1.403972	321	SWAP70 TEK DLC1 WNT4 RDX GPR65 ARHGEF15 SHANK3 TMOD3 CCDC88A INPP5K BAG4 KANK3 CAV1 MYADM BAIAP2 CDC42EP2 ESAM S1PR1 CDC42 CIT SCN5A RHOA SPIRE1 JAM3 RGCC CRK SFRP1 SPTBN1 PDE4D PDGFA SORBS3 RHOB ROCK2 SYNPO TNNC1 BST1 ROCK1 VASP COTL1 C9orf72 ACTR3 CAPZA2 PLEK DSTN ADD1 ARHGDIB ACTR2 LMOD3 HCK MTPN NCKAP1L ARHGAP17 KANK1 MYO1C FAM107A TMOD1 WASF2 SYNPO2 RHOBTB2 RAC2 ARHGEF10 RHOG RHOJ PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 SIGLEC15 PPM1F SNX9 RHOQ WNT11 WHAMMP3 EPHA3 CLASP2 ACTN2 PDE4B ICAM1 ABL2 ARPC2 WDR1 LMOD1 CDC42EP3 TMOD2 ARHGAP18 DIXDC1 RND1 LIMCH1 RAPGEF3 EDN1 ARPC5	down	**
GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN	0.0055919	0.0464297	0.4070179	-0.2665431	-1.403483	170	FGD5 RASIP1 CYP27A1 LPXN BMPER INPP5K ESAM C3orf70 UBL3 SLC7A7 TMEM204 TFEC SPI1 TCF7L2 CST3 SNED1 BIRC2 EPOR CASP1 PLEKHM3 OSTF1 DRAM1 TPP1 ITGAX CXCL2 C9orf72 FRMD4A RUFY3 CD8B IL6 SYNPO2 LRCH1 SLC16A11 CSTA SNX2 FBXL16 PSTPIP2 GRB2 NPR1 THSD7B RALB CGGBP1 SIGLEC1 YPEL2 STXBP3 CD1D TEX14 TBRG1 RELL1 ATP6V0C GNB4 ADAMTS15	down	*
HORIUCHI_WTAP_TARGETS_UP	0.0023742	0.0244316	0.4317077	-0.2517681	-1.403193	268	CXCL3 ACP5 HMOX1 ABHD5 CXCL16 EDNRB EMCN NR3C1 USP47 PPM1D RFTN1 ZEB2 TXNIP PTPRM ASAH1 ENTPD1 ZNF503 PAQR3 ZBTB8A TFEC CD58 PER3 ARRB1 CASP1 BST1 KLF4 TPP1 SSH1 RIT1 NR1D2 CXCL2 ATF3 RECK IL7R FOXN3 LACC1 PRCP MYLIP FLT1 SAR1A CYB5R1 C2CD2 SNX29 OSTM1 DNASE2 IFRD1 PCGF5 ENTPD4 TMEM167B PDZD2 CXCL5 APH1B PELI1 HIVEP2 TREX1 WHAMMP3 SMCR8 TSC22D1 DUSP5 LRRC32 PCDH17 SOD2 ANKRD12 STX12 RGS2 ZNF267 TAGLN ICAM1 CPQ OPN3 FAM167B TFPI CEBPD ALDH6A1 BRWD1 LIMCH1 FNIP2 RORA CREG1 RNF13 MAN1C1	down	*
GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN	0.0043644	0.0386820	0.4070179	-0.2622533	-1.403004	187	SIDT2 PPARG CPEB2 LTA4H USHBP1 RAMP2 LMO2 SOX17 CAV1 GAS6 SLCO2A1 PDE2A LACTB PCYOX1 C16orf89 CAV2 ADIPOR1 SPTBN1 EVI2B KIF1C DUSP3 PAPSS1 ELK3 ADIPOR2 KLRD1 FAM76B HEXB S1PR4 AK1 PODXL RPS6KA1 PRKACA NDST1 TPRA1 MBP CD74 ZNF521 TGFB1 TSC22D1 THAP11 RGS2 ABI3BP GSTM5 TIAM1 PIP4K2A ALDH2 CCR9 ULK2 SREBF2	down	*
GCACTTT_MIR175P_MIR20A_MIR106A_MIR106B_MIR20B_MIR519D	0.0001141	0.0021561	0.5384341	-0.2358591	-1.402693	510	SMAD6 WEE1 SLC24A4 RAB11FIP1 EPAS1 EREG SASH1 TAL1 FGD5 TBX3 DPYSL2 ST6GALNAC3 SIK1 EGR2 NEDD4L QKI CRY2 BMPR2 PAFAH1B2 S1PR1 DYRK1A OTUD4 TGFBR2 TXNIP ZBTB4 RAPGEF4 MAP3K8 PBX3 LUZP1 CAMTA1 PEX5L PPP2R2A FOXJ3 PPP3CA RB1 SRSF2 LHX6 NDEL1 CRK AKT3 BTG3 MCL1 FBXL5 EFCAB14 TBC1D9 TLE4 KCNMA1 PTPRO BNIP2 PPP6R3 KIAA0513 TNFSF12 KLF9 KLF11 ATL3 CDKN1A NPAS3 NKIRAS1 CEP57 CCND2 M6PR FRMD4A CCSER2 ELK3 SMAD7 CLIP4 CYP26B1 PAFAH1B1 KPNA3 CRIM1 TANC1 RSRC2 TOPORS SERTAD2 CREBRF FLT1 DNAJC27 PKNOX1 PHTF2 DDHD1 PLEKHA3 PPP6C ANKRD9 HECA C2CD2 SH3BP5 ZFP91 ARHGEF10 RABGAP1 APBB2 VPS26A DUSP8 PIK3R1 DDX5 KBTBD8 MAPK4 RPS6KA1 NAA30 RASSF2 DEDD IP6K1 MORF4L1 SPRY4 YPEL2 YTHDF3 PKD2 TSHZ3 PKIA BTBD7 TIMP2 ZFYVE9 CDC37L1 C16orf72 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 PLEKHO2 KAT2B PHLPP2 RBL2 INTS6 INO80 OSR1 EPHA4 SSH2 NPAT FOXJ2 PTEN SKI DNAJB9 FAM126B FAM13C ITCH DAZAP2 LDLR NRP2 ZFPM2 NABP1 WDFY3 SPOPL PURB EHD3 ANO6 TRIM36 EIF4G2 ZFYVE26 ARHGEF18 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 NR4A2 CLOCK DCUN1D3 TGOLN2 CMPK1 RB1CC1	down	**
MIR3140_3P	0.0044193	0.0390604	0.4070179	-0.2621563	-1.402485	187	SEMA6A OSBPL1A CD55 SLC16A12 KL BMPR2 DYRK1A NR3C1 WWC2 WNT2B CHMP1B C1orf21 COL4A2-AS2 CAV2 PEX5L JAM3 AKT3 TCF7L2 ZMIZ1 CYBRD1 ZSWIM6 ACSL3 FMO2 AQP4 SLC6A6 PRDM5 PDE1C C2orf69 SNX3 RBPJ CREBRF VPS37A MAGI2 PI4K2B RGS13 APOL4 SLC35F1 CR1 MME GLRA3 FEM1B CDC37L1 KHDRBS1 CBFA2T3 MAP3K2 PCDH17 INTS6 TAB2 RBMS3 FNIP2 CAMSAP2 C21orf91 NRG1 ZFPM2 PURB MIER3 AFTPH	down	*
GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN	0.0056333	0.0467431	0.4070179	-0.2670997	-1.401816	167	ACP5 FAM167A VAMP2 YPEL5 MAL GIMAP6 ANXA1 DPEP2 C1orf21 ADRB2 PDE4D SORBS3 EVI2B TLE4 AHNAK KIAA0513 ID3 LAPTM5 PDE3B NR1D2 PNRC1 SMAD7 IL7R C16orf54 CREBRF S1PR4 KLRB1 GIMAP2 EPC1 PIK3R1 TNFRSF10B YPEL2 MBP GIMAP1 EHD1 APBB1 HBP1 RIMKLB RGS2 CLEC2B SESN1 TFPI CXCR4 CDKN1C CAMSAP2 GIMAP4 HPCAL4 ARRDC2 JMJD1C-AS1 FAM8A1 PLEKHA2 SLC26A11 MICAL1 ATP2B4 MAP3K1 MEF2D CSF3	down	*
GO_NUCLEAR_CHROMOSOME	0.0000447	0.0009853	0.5573322	0.2752959	1.401437	864	HMGA2 SIM2 MNX1 ONECUT2 ONECUT1 HNF1A TP63 DDX11 FOXM1 FOXA3 RUVBL1 CDC45 MCM10 PAX9 ASCL5 TFAP2A BUB1B HOXD8 NEK2 TRNP1 CCNB1 SOX2 TIMELESS HOXB6 ZFHX4 CPSF6 NPAS1 TSHZ2 THOC3 NDC80 PRIM2 PIF1 BRCA1 SPDEF CREB3L4 FOXD4 SIX4 ZFHX2 GINS1 E2F8 FOXE1 NPAS2 POLE NABP2 IRX6 PLK1 NUF2 AURKB CENPA SIX1 EBF3 TBX19 SOX9 E2F3 TFDP2 FIGNL1 UHRF1 MCM4 HOXB7 MCM2 GRHL3 SP5 ORC1 HNF4G ASXL3 GINS4 NCAPD2 RSPH1 RUVBL2 SMARCD3 SMARCC1 SOX30 STAG3 CHAF1A FOXA1 TP53BP1 FOXJ1 BUB1 MSX2 TOP2A AURKA EME1 CBX3 REC8 POLA2 SYCP2 ATR POLD2 IRF3 SMARCAL1 MCM7 ZNF174 E2F2 MSX1 MMS22L CDCA5 PRKDC TRRAP WDHD1 CSRNP3 HOXC6 HELB MCM3 CHAF1B HORMAD1 SOX4 BRD9 EME2 ZNHIT1 TOPBP1 CHEK1 ORC6 ACTL6A NFYA SOX11 CENPO CSRNP2 RAD51AP1 XRCC1 THAP10 HES6 MGA EHF HSF4 REPIN1 BLM GRHL2 PML HOXB5 MEOX1 TFCP2 PARP1 INCENP ETV7 CBX5 ASF1B CDK1 CDK12 POLE2 BIRC5 PHF12 ZMIZ2 E2F1 TBX15 PRRX2 STAT2 DNA2 POU5F1B FEN1 EZH2 THAP8 TTI1 CBX1 ARNT2 IRF6 TBX1 TELO2 ZGPAT OVOL3 FOXK1 TRIM24 TUBG1 DCLRE1C ALX4 SATB2 ADNP DVL3 RAD9A HIRA RAD51D MTA3 SUDS3 SSRP1 NFATC4 HDAC1 ESCO2 GINS2 ANP32E LRWD1 OTX1 CHD5 CDK13 POLD1 THRB ESR1 ENC1 SLX4 RAD50 NR6A1 ETV4 CENPK PROX1 KLHDC3 EP400 NFXL1 BRD8 HNF1B TWIST1 RPA1 TFCP2L1 NOL6 MCM6 HOXA3 DNMT3A THOC5 WRNIP1 ZNF446 MCM5 ZRANB3 TFAP4 ADD3 NFE2 ESRRA CREB3L2 ETV6 RCC1 SMARCC2 ESRRB ZNF580 MSH4 LHX4 MCRS1 MSH2 SMARCA4 PRIM1 NFRKB GRHL1 BBX MLXIP STAT6 INO80E RAD51 TNKS1BP1 BRMS1 CHMP1A FOXD2 LBX2 SOX12 CHD3 HOXB2 MXD3 SIRT6 SMC2 TONSL TCF3 SRCAP SWI5 TP53 ZBTB32 APEX1 TAF4 NCAPD3 RORC RAD1 SMARCB1 E2F7 RRS1 NAT10 MUC1 THAP3 HOXA6 ZFPM1 ASCL2 ACTR5 SS18L1	up	***
MIR607	0.0000043	0.0001375	0.6105269	-0.2216829	-1.400655	815	TRIM71 GPATCH11 FOXF1 ZMYND15 SWAP70 ABHD5 SPN ATXN3 LHCGR PTPRB KL TMEM170B PLEKHF2 BACH1 KIAA1109 CORO1C THAP2 AQP9 QKI BMPR2 ZCCHC2 GTF2I PLEKHA1 PAFAH1B2 MTMR10 IDI1 EOGT MOB1B RCHY1 SCARA3 SPCS3 ZEB2 ZBTB4 CNST STARD4 ATP2B1 DNAJC3 LACTB TACC1 FAM124A LATS2 BZW1 SERINC1 RNF144B NLK SPIRE1 KLF10 KLF6 SLC7A11 PPP2R2A ZBTB8A FOXJ3 SRSF2 CD93 SPRY2 ZFYVE16 TFEC CYP4V2 GPM6A TIPARP PTPN12 CWC22 TBC1D9 RAB12 FOXO1 KCNMA1 PPP6R3 CASP1 TSPAN12 ITM2B STK17B KLF7 SPAG9 ERP44 MGAT4A NR1D2 NKIRAS1 CTBS TADA2B C9orf72 UXS1 CD302 RECK LBH ACTR3 UBE2B ILDR2 PEAK1 GNAQ ZNF706 KIAA0408 UBASH3B PRDM5 TP53BP2 NRBF2 IKZF5 TLL1 EFR3A MEDAG LIN7A ACTR2 SERTAD2 ARL6IP5 TFAP2E FLT1 CCNY RNF149 PDIK1L CREM SYNPO2 PKNOX1 PHTF2 CTSS NEK7 APPL1 RAB8B PDCD6IP NECAP1 ARL5B MITF LRCH1 GABPA ZFP91 KCTD12 BMP3 MSRB3 CNTN4 OSTM1 FOXN2 MTMR9 VPS26A TBC1D12 DHX15 FYTTD1 TTC14 SP3 ACKR3 CD83 DDX5 CREB1 PTGER2 COBLL1 FSD2 RC3H1 FSD1L PRKACA PDZD2 PREX2 NAA30 DENND4A ZNF407 BLOC1S6 AGFG1 POGLUT1 SLC25A24 PELI1 AGPS CDK17 AZI2 HIVEP2 YTHDF3 PKD2 TSHZ3 NAA16 SYPL2 AZIN1 AKIRIN2 STRN AP1G1 NDUFA5 ZBTB1 SRSF4 PDS5B HECW1 CRYZL1 ABHD13 TEX30 VAMP4 FEM1B MTMR2 MIA3 MAP3K2 PLSCR4 PPP3R1 TAGAP THAP9 TMEM70 STX12 MBNL1 SMAD2 INO80D BMP2K GEM INTS6 NEK1 PDLIM5 SFT2D1 ACAP2 TEX10 THAP6 FBXO30 ARIH1 CYP2U1 RBM18 UBE2D1 TBC1D1 USH2A POLR2M ZNF471 ZDHHC21 RBMS3 LYSMD3 CUL3 BCAT1 SCAI DNAJB9 TLK2 PRKG1 PDE8B C21orf91 RORA FAM13C FAM13B GSPT1 NDUFAF5 CNOT8 SPOPL PURB MACROD2 BANK1 ARFGAP3 SPATA13 ZBTB44 SLFN11	down	***
PHONG_TNF_RESPONSE_VIA_P38_COMPLETE	0.0024507	0.0249881	0.4317077	-0.2578337	-1.399966	204	HHEX FABP4 EMP2 INSIG1 BACH1 CAV1 HMGCR NR3C1 OTUD4 CCNL1 WWC2 ATP2B1 ADAM17 ITGA5 KLF10 CRK ITSN2 MCL1 FBXL5 PTPN12 KCNMA1 SDCBP ACSL3 ZCCHC24 MAFG MYO1B SPAG9 ATF3 IL7R AFF1 BTG1 NINJ1 MYO1C NXF1 NOTCH1 HMBOX1 SH3BP5 MAP4K4 PPP1R15A SNX2 GLIPR1 TCP1 PPM1F FOS RHOQ MBP FOXO3 MSMO1 TCF4 TGIF1 DUSP5 GABARAPL1 ETS2 PITPNA MGAT2 S100A4 METTL7A LIMCH1 RET TMEM87A DLST C2orf42 EHD3 PMAIP1 EGR1 UBR2 SVIL	down	*
GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP	0.0058050	0.0477497	0.4070179	-0.2655747	-1.398384	170	ADCY9 RCOR1 MMRN1 CITED2 AQP9 ZCCHC2 MKNK1 TGFBR3 CD9 MOB1B STARD4 NLK RNF125 SPIRE1 DACH1 PTPN12 PER3 EPOR PIP5K1B FAM76A KLF11 TJP1 MPL ZBTB43 VAMP5 CA1 VWF CREBRF UTRN NDNF CPEB4 OSTM1 ENPP4 GYPC FRYL SLC25A24 ZBTB11 HACE1 YAF2 EPB41L5 GIMAP5 SIK3 P2RX1 CCND3 GRB10 MT2A WDFY3 GHR SH3GLB1 RAB37 PLXDC2 CCNT2 OTUB2	down	*
GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_UP	0.0058050	0.0477497	0.4070179	-0.2655064	-1.398024	170	CD300LF ZMYND15 OLR1 TMEM52B CD55 IL1B CYP27A1 TIE1 GFOD1 PRAM1 GTF2E2 TMEM138 TBC1D2 AGPAT4 FGR PTS SLC36A4 CYB561A3 ABHD6 LAIR1 ANKRD29 EIF1B LCMT2 BST1 CDKN1A N4BP2L1 FKBP15 CD300LB SNN MTMR14 SMIM20 TAGLN2 ACSL1 POGLUT1 SIGLEC17P RNASEK HIVEP2 CR1 FXYD6 DOK3 CD1D TMEM230 LRRC32 APLP2	down	*
MIR369_3P	0.0015220	0.0174336	0.4550599	-0.2532976	-1.398008	257	SMAD6 GCOM1 BMP2 KL IDI1 DYRK1A WBP4 SCN5A PLXNA2 RANBP9 PAQR3 SLC7A11 SRSF2 ZEB1 PDE4D PTPN12 TBC1D9 CCL22 TLE4 PTPN21 FOXO1 TBX4 BNIP2 ZSWIM6 ZNF423 TJP1 CEBPA KLF7 FBXL3 MGAT4A LRRC40 PNRC1 CAPZA2 GCA HES1 BACE1 LIN7A RBPJ PRDM11 RYBP PHACTR2 HSD17B13 C11orf58 FOXN2 ELOVL7 SP3 MBNL2 RC3H1 HOMER1 PREX2 DENND4A GRIK1 OCIAD1 PELI1 YTHDF3 ZNF521 VAV3 TCF4 NDUFA5 MAP3K2 C8orf37 TAGAP RIMKLB LTBP1 ADAM10 PDE4B YAF2 TRAPPC8 POLR2M FNBP4 RASSF8 JMJD1C RNF38 SKI PDE8B MMD RORA SHISA6 UBAP1 EGR1 CFL2 GJC1 ATF2 UBA6 USP30 MZT1 TBC1D23 PIGK UBE3A PLN CAPZA1 SGPP1 RNF214 EP300 DR1 RAB39A SETD2 RC3H2 RAB11FIP2 FNIP1 SEMA5A PEX13	down	*
GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN	0.0051669	0.0439258	0.4070179	-0.2669986	-1.397967	166	SLPI SLC31A2 ACVRL1 CD52 OSBPL11 HVCN1 DPYSL2 LY86 INPP5K CITED2 TBC1D2 ANXA1 ATP2B1 ANXA5 STOM CD93 EVI2B MSR1 ZCCHC24 SLC7A8 CEBPA VIM PAPSS1 HOPX HPSE ALOX5AP MPC1 ANXA3 TDRD7 PGD SERPINB8 RAB31 VPS26A GLIPR1 SDHD GPR183 TAGLN2 RBKS LGALS3 ICAM1 ANKLE2 RTN4 CEBPD TIAM1 SEC61B NLRP3 PSME4	down	*
AGCACTT_MIR93_MIR302A_MIR302B_MIR302C_MIR302D_MIR372_MIR373_MIR520E_MIR520A_MIR526B_MIR520B_MIR520C_MIR520D	0.0010626	0.0133296	0.4550599	-0.2533089	-1.397840	282	WEE1 RAB11FIP1 EPAS1 EDNRB TAL1 FGD5 KLF13 SIK1 OTUD4 SYNC TXNIP ZBTB4 UBR3 LATS2 PBX3 CAMTA1 LHX6 CRK MCL1 TIPARP TLE4 KCNMA1 NPAS3 CCND2 FRMD4A UBE2B CLIP4 MPC1 CYP26B1 CRIM1 RSRC2 RAB6A BTG1 CREBRF FLT1 DNAJC27 DDHD1 PLEKHA3 PPP6C C2CD2 ZFP91 ARHGEF10 RABGAP1 FBXO11 KLHL18 MBNL2 KBTBD8 RPS6KA1 YWHAZ RASSF2 COL23A1 IP6K1 CELF2 YPEL2 YTHDF3 TSHZ3 SPOP ZBTB11 C16orf72 ATXN1 PPP3R1 HNRNPH3 PHF2 KAT2B PHLPP2 PRDM8 SMAD2 INTS6 INO80 TOB2 EPHA2 FOXJ2 MTUS1 FAM13C DAZAP2 ZFPM2 PURB ANO6 MIER3 TRIM36 DNAJA2 IRF2 ZFYVE26 ARHGEF18 PLAG1 ARHGEF17 CFL2 ZNF800 NR4A2	down	*
GSE360_DC_VS_MAC_L_DONOVANI_DN	0.0058050	0.0477497	0.4070179	-0.2654100	-1.397517	170	ACP5 USP12 CD55 MNDA RDX FYN LPL LY86 ST3GAL6 MYD88 CD9 SLC11A1 EPB41L3 NUMB SLC7A7 KLF10 RNASE1 TPP1 PDE3B ATF3 CTBS ADIPOR2 CUL5 OXSR1 RPS6KA2 METAP1 MUC3A NSMAF BTD IDS PTGER2 CDK2AP2 STX5 RPS6KA1 TNFRSF9 CLN3 MSMO1 AZIN1 GSAP ZBTB1 TSC22D1 PIK3C3 CCR1	down	*
GO_REGULATION_OF_DEFENSE_RESPONSE	0.0000407	0.0009124	0.5573322	-0.2289450	-1.396327	610	FFAR4 SIGLEC11 GPR17 NLRC4 EREG ACP5 CD300LF IL17RB FOXF1 FCN1 TEK EDNRB SCIMP SIGLEC16 PPARG PGC WFDC1 IL1B FABP4 MNDA CDH5 FYN LPL SAMHD1 CLEC12B CAV1 CALCRL MYD88 CLEC10A RBM14 MARCO CASP12 IL1RL1 OTUD4 PSMD5 LAMP1 RFTN1 IL23A FGR DNASE1L3 PDE2A APOD CD36 ANXA1 MIR146A PLA2G7 ADA CLEC7A TNIP3 RNF125 FOXP1 IFNK SERPINB9 GATA3 SIRPA RB1 TRAF6 GRN CRK CRTAM UBE2D3 CASP5 SLC7A2 IL10 BIRC2 MEFV CASP1 BST1 SLC46A2 KLF4 CEBPA SOCS5 LY96 UBQLN1 CCL3 NFKB1 CADM1 NR1D2 PTPRC IRAK2 TLR4 PTGER3 SFTPD FCER1G PER1 ZMPSTE24 PTGIS PIAS1 HCK IL17D IL6 MUC3A CD160 CTSS SOCS3 APPL1 SEC14L1 PSMA1 ETS1 HSPA1B IFNGR1 JAK1 PTGER4 CCR7 PRKCE OSM MALT1 UNC13B PRKACA SUCNR1 CST7 PLCG2 UBB PELI1 BCL6B YTHDF3 PSMD12 ICAM2 TREX1 CR1 PIK3AP1 SMPDL3B AP1G1 CD1D CD6 FPR2 YTHDF2 NLRP6 PIK3C3 CNOT7 CD81 KLRC4-KLRK1 IFNLR1 SYT11 IL18 IL18RAP ARRB2 RTN4 TAB2 RIPK2 NLRP3 UBE2D1 HAVCR2 PSME4 CREBBP ICAM3 TLR10 SIN3A NFKBIA ADORA2A CTSC PAK2 KLRK1 AIM2 RORA ITCH LDLR PSMD6 PSMD9 SFPQ PUM1	down	***
GSE25088_CTRL_VS_IL4_STIM_MACROPHAGE_UP	0.0057651	0.0474981	0.4070179	-0.2625736	-1.396098	175	LIMS2 SWAP70 STAC HVCN1 GPIHBP1 ZC3H12C CAT DPYSL2 LY86 KANK3 ADA CD33 C1orf21 ITGA5 AHRR PARVG ITPK1-AS1 NFE2L2 CD93 ARL11 PTPN12 EFCAB14 AMOTL1 LINC00877 SOCS2 IGFBP2 SNN FAM102B FOXN3 CD8B SPIN1 SGK1 SEC14L1 CCDC50 SP3 CREB1 GRASP DLEU2 LMCD1 BCL6B TCF4 PDLIM1 ATXN1 GNB4 ETS2 RXRA	down	*
GO_TAXIS	0.0001944	0.0033570	0.5188481	-0.2349754	-1.395737	507	TNR DAB1 SEMA6B SEMA3G CXCL3 SEMA6A IL1A SWAP70 CXCL16 EDNRB ROBO4 SPN IL1B DPYSL2 PLA2G10 BDNF FYN SHANK3 EGR2 CCL3L1 ECSCR CCRL2 FOSL1 CDH13 BMPR2 C5AR1 S1PR1 FGF10 DSCAML1 IL1RN GAS6 IL23A RHOA SEMA6D ANXA1 PLA2G7 PTPRM SEMA3B HBEGF SBDS ADAM17 PLXNA2 HSPB1 RANBP9 GATA3 NR4A1 JAM3 PLXNA4 CRK SPTBN1 WNT3A PDE4D PDGFA IL10 DUSP3 CCL22 PTPRO BST1 ZSWIM6 PTAFR PLAUR PSPN VASP THBS1 STX3 KLF7 CCL3 CXCL2 ID2 CCL4 SFTPD XCL2 FCER1G DUSP1 MATN2 OXSR1 UNC5A AKIRIN1 SIAH1 TGFB2 NCKAP1L FLT1 IL6 LAMB2 NOTCH1 HRH1 RAC2 CNTN4 RHOG APBB2 CCR7 DAPK2 PIK3R1 ACKR3 GRB2 GPR183 CREB1 SUCNR1 CXCL5 PPM1F CD74 BIN2 CCR4 EPHA3 TGFB1 VAV3 ITGA9 FPR2 IRS2 LGALS3 DOK2 KLRC4-KLRK1 CCR1 NPTN GPR18 ADAM10 PDE4B CCL20 CCR6 FGF2 ARRB2 SEMA4A TIAM1 CXCR4 EPHA4 CCR9 PTCH1 EPHA2 PARVA PLGRKT RET KIT EDN1 KLRK1 B3GNT2 MTUS1 LYST FGFR1 NRP2 DOCK4 NRG1 GRB10 IL16 SMAD4 FEZ1 ANO6 FEZ2 RAP1GAP GREM1 SERPINE1 C5AR2 CNR2 CX3CR1 C5 MAPK1 MYH10 TREM2 S100A8 FPR1 NOG EFNB2 PIK3CG CALR FPR3 BSG	down	**
MIR520D_5P	0.0000200	0.0005024	0.5756103	-0.2195018	-1.394916	810	AJAP1 MGAT3 SC5D IL1A SGK3 TAL1 SECISBP2L CPEB2 LTA4H SLC16A4 PTPRE LIPA PTPRB ZBTB34 TMEM170B BDNF PLEKHF2 MED4 DDX6 QKI DYRK1A CDC42 FBXO3 GNPTAB TSHZ1 TET2 NFATC3 SPCS3 HEG1 TMX4 ZEB2 TXNIP ARHGAP29 WWC2 ATP2B1 CACNA2D2 LATS2 RAB33B BZW1 MAP3K8 RANBP9 COX18 KLF6 RNF182 GLS CAV2 PTX3 CAMTA1 ADIPOR1 EIF4E DACH1 FOXJ3 PPP3CA RGCC SRSF2 LHX6 HNRNPDL TFEC HNRNPU TCF7L2 UBE2D3 TFRC RAB14 ZYG11B GPM6A ZMIZ1 PTPN12 MSR1 TLE4 RAB12 FOXO1 DGKE SCP2 BNIP2 TCP11L2 ACSL3 KLF4 FAM76A REST PRKD3 DRAM1 TJP1 SEC24B C1QTNF7 PER2 LRRC40 IRAK2 CYP20A1 PNRC1 CEP57 ZBTB43 CLK4 UBE2B MBD2 RAP1GDS1 SLC6A6 PRICKLE2 OXSR1 UBASH3B PAFAH1B1 BCLAF1 SMNDC1 FAM76B AKIRIN1 EFR3A CNOT6L RSRC2 CNRIP1 NCOA1 SIAH1 FAM102B USP25 RBM39 GPBP1 CREBRF PRKRA SCEL ID4 ELF1 PDIK1L CREM YBX1 DDHD1 SGK1 HSD17B13 EBF2 HCFC2 PPP6C SERPINB8 JUN ARL5B MITF STAT4 GABPA GLUD1 DDX17 C11orf58 BMP3 MSRB3 HSPA1B OSTM1 EPC1 SKIL ENPP4 SP3 ACKR3 CREB1 ZNRF3 PREX2 CGGBP1 MEAF6 AGFG1 CTTNBP2 PELI1 AZI2 HIVEP2 USP7 PPTC7 MAPK8 PKIA RIN2 TTBK2 BTBD7 EPHA3 SORT1 GOLGA8R VAV3 TCF4 ATG2B SERPINB1 VAMP4 RSBN1L SBF2 GOLGA8H ZC3H12D ATXN1 CSDE1 PPP3R1 GNB4 GNA13 KAT2B ADAM10 PDE4B CALB1 ETS2 MBNL1 ATAD2B ARPP19 SMAD2 INO80D RNF138 SESN1 INTS6 SLC34A2 ZNF583 CEBPD LRP12 TRAPPC8 TAB2 FBXO30 ARIH1 MEGF9 HNRNPK G3BP2 GRIN3A SRSF10 KPNA4 VSIG10 NPAT TTC28 DOCK10 SCAI FAM126B KIF1B RORA FAM13C DOCK4 RHOT1 SFPQ GSPT1 CNOT8 WDFY3 PUM1 EID1 MIS18BP1 SPATA13 INTS10 ZBTB44 IRF2 HNRNPH1 VPS13D PSIP1 EGR1 TMEM50A DUSP6 TMEM30A ZNF106 CENPC NR4A2 HIPK1 ATF2 UBA6 MAPK1 SSB CLOCK	down	***
GSE7548_DAY7_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP	0.0042908	0.0381884	0.4070179	-0.2643300	-1.394655	171	SWAP70 FABP4 GPR65 BMP2 KANK3 QKI S1PR1 CD9 TRIB1 NUMB CD36 PICALM LITAF FBXL5 ZMIZ1 EXOSC9 BNIP2 ID3 THBS1 PDE8A PAFAH1B1 SACM1L RBPJ ID4 PPP2CA CREM PIKFYVE SEC14L1 STAT4 PNMA2 LTBP2 HRH1 IFNGR1 VPS26A AK1 DUSP8 ATP13A3 CELF2 HIVEP2 CD86 TERF2IP NPTN ATAD2B CCL20 GEM CEP170 TFPI TRAPPC8 ITGAE PTCH1 THEMIS2 CREG1 TLK1	down	*
GO_RESPONSE_TO_NUTRIENT	0.0061245	0.0497709	0.4070179	-0.2648448	-1.394541	170	SLC6A4 HMOX1 PPARG IL1B CAT P2RY1 TRPC3 FOLR1 FYN LPL BAIAP2 TBXA2R HMGCR GAS6 TGFBR2 ATP2B1 ADA FOXA2 ARSB SFRP1 KANK2 MTHFR ACSL3 BCHE SSH1 P2RY2 SELL IGFBP2 ADIPOR2 CYP26B1 GNAI2 NCOA1 SRF SLC8A1	down	*
MOOTHA_MITOCHONDRIA	0.0029588	0.0288286	0.4317077	0.2871984	1.393775	371	CPS1 BIK AK4 BDH1 TSFM SLC25A21 MRPL46 NPIPB3 NDUFS6 TOMM34 NNT CYP27B1 SHMT2 MRPS35 COX11 CASP2 NDUFB8 SDHA MRPL15 PCCB NDUFS2 LARS2 MPO AMACR MRPL3 OAZ3 EHHADH MRPS11 CAD ETFA FDXR MRPS30 TST IDH2 SLC25A10 UQCR11 MB SSBP1 PLA2G2A GOT2 OAT ACP6 MCAT MRPS2 PRPF6 SLC25A13 MRPL17 PDK1 MRPS12 ETFB MAST1 CPT1B UQCRFS1 NFS1 SPG7 MRPS34 LONP1 DHODH MRPL11 TPO COX7C PPOX MRPL4 DAP3 SLC1A3 COX10 NT5M YARS2 TIMM13 SIRT4 BCL2L1 MRPL24 MRPS33 CKMT2 MRPL28 HAX1 AMT FARSA PYCR1 POLR3B NME4 ABCF2 UQCRC1 COX5B ECHS1 MRPL9 NDUFA8 NDUFS8 ERBB2 CPOX TBCB VDAC3 POLR1B MTHFD1 TP53 SBNO2 TIMM44 MRPS27 BCAT2 MRPL20 ADCK2 MRPL48 NDUFB7 COX6B1 DNM1L TK2 COX17 ACAD8 CYP11A1 CYB5B TFB1M SARDH BCKDK POLRMT MRPS16 UCP3 DGUOK MRPL12 CRAT BAK1 MRPL2 TOMM40 TIMM10 TYMP MPST SHB IMP3 CS PPA1 NDUFB2 TXN2 PC COX15 TIMM9 LYPLA2 MTHFD2 COX6A1 METTL17 FIBP COX6C ABCB8 SDHC MRPS7 ACADS MRPL35 MRPL13 GATM MRPL33 CROT NDUFA10 BCKDHA SUCLG1 DDX28 IDH3A TIMM23 NDUFS4 TNFSF10 CYP2E1 PYGB CNNM4 PMPCB NPIPA1	up	*
GSE27786_LIN_NEG_VS_NKCELL_DN	0.0046649	0.0405343	0.4070179	-0.2621045	-1.393743	176	CD300LF USP12 LYL1 CCDC88A PRAM1 BMPR2 CTDSP1 CD22 HPS5 RCHY1 TACC1 NAAA PBX3 ARHGEF2 MTHFR PPP3CC PTPN12 TBC1D9 PTGIR NOSTRIN CDK9 ITPK1 CTBS TM6SF1 SMAD7 INHBA HES1 MARK3 CDC40 PDCD6IP ETS1 ATP6V0B JAK1 ATXN1L SNX1 AGFG1 DGKG SORT1 TFEB VAMP4 C16orf72 ICAM1 ITPRIPL2 RTN1 TRAPPC8 ISCU CEPT1 TMCC3 PURB ATF2 CLOCK ARL4D ATP1B1 FAR1	down	*
GO_LEUKOCYTE_DIFFERENTIATION	0.0001813	0.0031551	0.5188481	-0.2386810	-1.393578	430	CD101 TAL1 PPARG HHEX GATA2 SPN SNX10 DCSTAMP WNT4 OSCAR LYL1 PDE1B CDC42 GAS6 TGFBR2 TRIB1 LILRB3 IL23A CD8A RHOA ANXA1 CLCF1 FBXO7 ADA ADAM17 KLF10 FOXP1 KLF6 HLX MS4A1 IFNK GATA3 RB1 IL18R1 TRAF6 SFRP1 ZEB1 SPI1 TFRC ZMIZ1 EVI2B IL10 NRARP SLC46A2 FUT7 CEBPA SOCS5 CCL3 PTPRC AXL ID2 TLR4 FCER1G SMAD7 INHBA IL7R UBASH3B CYP26B1 PAFAH1B1 MIR17HG SRF NRROS NCKAP1L RBPJ CD80 IL6 PKNOX1 PSEN1 JUN MITF CUL4A TYROBP JUNB OSTM1 PTGER4 CCR7 SP3 PIK3R1 CD83 GPR183 CREB1 MALT1 SIGLEC15 RC3H1 AP3B1 FSTL3 TBX21 RASSF2 ZNF683 PLCG2 FOS RRAS AZI2 RUNX3 CD74 CR1 TGFB1 CD1D ZBTB1 JMJD6 CBFA2T3 CD86 CD81 CCR1 MFNG GPR18 CCR6 IL18 SEMA4A RIPK2 NLRP3 TOB2 CCR9 EPHA2 CD19 KIT DOCK10 CD3G DNAJB9 TNFSF9 RORA	down	**
GO_PEPTIDE_BINDING	0.0042883	0.0381884	0.4070179	-0.2549467	-1.393541	210	HCRTR1 RAMP3 COL25A1 EDNRB TRHDE PPARG RAMP2 CALCRL ADCYAP1R1 MARCO CD1C HSPG2 CD36 SSTR1 PICALM ANXA5 FZD4 NMUR1 ANPEP PEX5L PPP3CA ADRB2 CST3 KPNA5 MSR1 ITM2B SLC7A8 BCHE TPP1 NPR3 TLR4 INHBA KPNA3 HLA-DQA1 BACE1 PTH1R TGFB2 C1QA APBB2 PIK3R1 NPR1 GRIA1 GPR37L1 CD74 MME NUP153 GSAP CD1D FPR2 APBB1 PPP3R1 PPIG PGGT1B PPID RXRA TIMM22 EPHA4 DLGAP3 IPO5 NUP98 KPNA4 NFKBIA CD1E	down	*
MIR4803	0.0004682	0.0069706	0.4984931	-0.2409214	-1.392139	376	EREG COL25A1 EDNRB SGK3 DENND5A GATA2 ZC3H12C TMEM170B BDNF VAT1L CALCRL QKI FBXO3 NR3C1 GIMAP6 TGFBR2 RCHY1 BRINP3 ATP2B1 HBEGF HECW2 RAPGEF4 LIFR ASAH1 ZNF503 GLS CAV2 SLC7A11 DACH1 FOXJ3 ZEB1 GPM6A PPP3CC ATP10A EVI2B NRARP MTMR6 ACSL3 ITM2B SLC38A11 REST LEPROTL1 KLF11 TNFSF15 ADAMTS9 FBXL3 ABCC4 TADA2B RECK SMAD7 N4BP1 VEPH1 VPS37A DDHD1 PHACTR2 APPL1 SERPINB8 JUN GABPA SNX29 EPC1 MTMR9 APBB2 TTC14 CREB1 LPCAT2 SLC10A7 PDZD2 YWHAZ AGFG1 CTTNBP2 CDK17 KLRC2 ZFAND6 CC2D2B GNAI1 ATP6V1A PPIG LTBP1 PDE4B ARPP19 INO80D HACE1 JUND BMP2K CEP170 TIAM1 LRP12 BRWD1 ZDHHC21 CREBBP LIMCH1 STK4 TMX2 CAMSAP2 FGFR1 DOCK4 ZFPM2 CNOT8 EIF4A2 SMAD4 HNRNPH1 ACVR1C EGR1 ACSM5 CDKN1B FUS PRKCH SH3GLB1 KIAA2026 CD109 CSNK1G3 CCNT2 PRTG UBE2W CHAC2 PIAS2 MTSS1 ANGPT2 SCAF11 MAN1A1 OMA1 ROBO2 TMEM165 SEMA5A CMSS1 MAPK7 PJA2 ZNF667 KLRC1 VPS13C FPGT-TNNI3K FBXO33 SON CSTF2T CAAP1 DYRK4 LEPROT TANK EIF3J	down	**
TIEN_INTESTINE_PROBIOTICS_24HR_UP	0.0013631	0.0161485	0.4550599	0.2807304	1.391349	504	PPM1H TRIP13 FOXM1 KIF20A HJURP GALNT6 BUB1B NUP107 CCNB1 CENPF DROSHA PAIP1 CPSF6 TTF2 NDC80 TBRG4 MRPL46 GINS1 RACGAP1 GTSE1 KIF14 DNMT3B PLK1 CENPA PTTG1 ESPL1 MCM4 MCM2 TYMS CDC25A UMPS PRC1 GLDC ZWINT LSM5 NME1 HMMR NUDT1 KIF23 BUB1 MSX2 AURKA TMEM177 LARS2 MCM7 TPCN1 RRM2 SMYD2 PDCD5 KIF11 MCM3 EMG1 BRD9 PLXNA1 MORC2 TOPBP1 DNAJC9 THYN1 MAD2L1 TRMT61B RAD51AP1 DCTPP1 PHB CNPY2 SKP2 CKLF GEMIN4 PON2 NUSAP1 NSF POLE2 EXOSC2 GMNN OAT POLR3K UNG MRPS2 SLC25A13 FEN1 SPAG5 SNRPE LAPTM4B SNRNP25 DNMT1 ST14 DPP3 TUBG1 DLGAP5 SPG7 COA3 UBAC1 ADAT1 ALDH7A1 LMNB2 TUBB2A HMGN3 TK1 ADAR GINS2 ANP32E AGPAT5 ENOSF1 NDUFA13 PSMD2 NUP85 SUPT16H TIMM13 BRD8 IARS2 ACLY RPA1 SRRT MCM6 MED24 MCM5 SNRPD1 LSM7 CLUH SRSF1 GINS3 LSM4 NEDD8 KLHL7 AGMAT TM7SF3 CCNA2 ADM GTF3C2 DENR PDF SHCBP1 ATOX1 TTC1 ECHS1 MRPL9 NDUFA8 UBAP2L AURKAIP1 PGAM1 VDAC3 TNS3 CIAPIN1 FAIM DDX52 PCBD1 SLC36A1 PNN MRPL20 NUP93 COX17 ARHGAP8 ERCC3 ERLIN1 NCAPH CYB5B TPM1 APOBEC3B RCN2 LUC7L3 MIOS C12orf43 ADSL LPCAT1 FBXO5 LGR4 FASTKD3 OPA1 KRIT1 TMPO GLRX5 MPZL1 MSH6 SAFB2 ABCD3 MTRR DGCR2 RBM8A NDUFB2 CCDC86 NAE1 HNRNPAB TIPIN	up	*
GO_ANCHORING_JUNCTION	0.0000662	0.0013638	0.5384341	-0.2231540	-1.391177	687	SLC6A4 LIMS2 AJAP1 WTIP ARHGAP31 TEK TSPAN4 PDLIM2 DLC1 PECAM1 RASIP1 KCNA2 CAT LPXN RDX RAPGEF2 CDH5 ENG CD44 TMOD3 CGNL1 STXBP6 DDX6 CAV1 CORO1C MYADM BAIAP2 CDH13 BMPR2 ESAM ADCYAP1R1 CDC42 NEDD9 IL1RL1 VAPA CD9 CBL EPB41L3 SCN5A HSPG2 HEG1 RHOA NUMB ANXA1 PTPRM ADAM17 CSRP1 TMEM204 ITGA5 HSPB1 PARVG ANXA5 FZD4 PCDH12 CAV2 LCP1 DES PPP3CA JAM3 TNS1 LAMTOR3 ARHGEF2 SGCA CNN1 SORBS3 EPB41L2 RHOB PTPN12 AMOTL1 SYNPO AHNAK SDCBP SORBS1 LIMS1 LIN7C YBX3 PLAUR KLF11 DAB2 PARVB VASP TJP1 STX3 CLDN5 CLIC4 CADM1 PTPRC VIM JAM2 FRMD4A ACTR3 CD53 SMAD7 PEAK1 VAMP5 ADD1 MAPRE2 LIN7A ACTR2 HCK PROCR ARHGAP17 KCNA5 FAM107A SLC8A1 SCN4B FLT1 WASF2 SYNPO2 SNAP23 MAGI2 PIKFYVE PDCD6IP AQP3 NOTCH1 LIMD1 RAC2 MAP4K4 HSPA1B RHOG RPL9 JAK1 FERMT2 PODXL PIK3R1 GRB2 CAP1 PDZD2 YWHAZ ITGA11 MCAM FGFR4 CD151 SPRY4 RRAS GJA4 PKD2 PRKCG EPPK1 FLNC MME PARD6A STRN TGFB1I1 PDLIM1 ATP6V0C CNTNAP1 CD81 CLASP2 GNA13 ACTN2 ADAM10 PRICKLE4 ICAM1 PDLIM5 LAT ARPC2 WDR1 EPB41L5 XIRP1 DCTN4 TIAM1 EPHA4 DIXDC1 ARL14EP HSPA8 ACTB HNRNPK EPHA2 RND1 RPS13 PARVA	down	**
NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON	0.0050944	0.0434964	0.4070179	0.2937655	1.391124	272	MYCBPAP EPN3 ANKFN1 COIL HOXB6 MKS1 SDK2 PRR15L LRRC37A3 UBE2Z SNF8 SOX9 PRKCA HOXB7 MAP2K6 CDK5RAP3 COX11 NME1 FOXJ1 FBF1 EME1 ITGB4 CACNA1G MPO RNF43 CHAD TOM1L1 MRPL27 B3GNTL1 SLC9A3R1 ACSF2 BRIP1 FDXR PHB LRRC45 HOXB5 ARL16 STXBP4 SLC25A10 KCNJ2 RECQL5 SLC39A11 PPM1E CD300A ZNF652 BIRC5 GDPD1 KIF19 NARF CBX1 CCDC57 EXOC7 COL1A1 CDK3 DHX40 XYLT2 LLGL2 NGFR GPRC5C TRIM37 TK1 HID1 TAC4 TSEN54 NUP85 NAT9 CCDC137 FN3KRP COG1 DUS1L LRRC59 ABCC3 DNAI2 SNX11 SKAP1 TTLL6 FSCN2 WDR45B LINC00482 NME1-NME2 TSPAN10 ENGASE PRR11 CANT1 RNF157 RSAD1 HOXB2 BCAS3 HGS RFNG COPZ2 SPATA20 WIPI1 FTSJ3 PCTP CHMP6 LUC7L3 SLC38A10 MBTD1 ARSG PDK2 UTP18 MRPL12	up	*
GO_AMIDE_BINDING	0.0012420	0.0150253	0.4550599	-0.2519072	-1.390836	260	HCRTR1 CD300LF RAMP3 COL25A1 EDNRB TRHDE PPARG RAMP2 FOLR1 GLTPD2 CALCRL ADCYAP1R1 MARCO CD1C HSPG2 CD36 SSTR1 PICALM ANXA5 FZD4 NMUR1 ANPEP PEX5L PPP3CA ADRB2 SLC19A1 CST3 KPNA5 MSR1 SCP2 ITM2B SLC7A8 BCHE TPP1 NPR3 TLR4 INHBA KPNA3 HLA-DQA1 BACE1 PTH1R TGFB2 PLEKHA3 C1QA APBB2 PIK3R1 NPR1 RTN4R GRIA1 GPR37L1 ECI2 CD74 PNPLA3 MME NUP153 GSAP CD1D FPR2 APBB1 PPP3R1 PPIG NQO2 ACADL PGGT1B PPID PCCA RXRA TIMM22 GLTP EPHA4 ALDH6A1 DLGAP3 IPO5 ACACB NUP98 SOAT1 KPNA4 NFKBIA CD1E GNMT	down	*
GO_MITOCHONDRIAL_ENVELOPE	0.0008434	0.0111569	0.4772708	0.2779767	1.390738	590	CPS1 HKDC1 BIK CEP89 BDH1 GPAT2 FLVCR1 COA1 CHCHD6 SLC25A21 SORD THEM4 MRPL46 ANKZF1 MSTO1 NDUFS6 TOMM34 ACAD9 ALDH18A1 SFXN1 NNT PRKCA CYP27B1 TYMS COX6B2 SHMT2 MRPS35 COQ3 COX11 AGK UQCC1 TAMM41 NME1 IKBKE NDUFB8 CISD1 GOLPH3 SDHA QTRT1 MRPL15 CYP24A1 GPER1 BPHL NDUFS2 TMEM177 COASY GCAT AKAP1 ERAL1 MRPL3 MRPL27 BLOC1S1 LETMD1 BRI3BP ABCB6 ASS1 COX19 SLC25A39 TIMM50 MRPS11 FDXR MRPS30 MTG1 PHB SLC25A10 UQCR11 COQ9 THOP1 MRPL36 MRPL37 GOT2 TRAP1 L2HGDH MRPS2 SLC25A13 MRPL17 COA4 MRPS12 ATAD3A NLN UQCC2 CPT1B CHCHD3 NRGN ULK1 CHCHD2 MYO19 IFI27L2 UQCRFS1 GNPAT NDUFA11 SPG7 COA3 FOXRED1 SPATA18 MTOR SLC25A18 MRPS34 DHODH C19orf12 MRPL11 MRPL52 COX7C PPOX DTYMK MRPL4 AGPAT5 DAP3 DNAJC11 NDUFA13 ACSL6 COX10 TIMM13 STOML2 CHCHD1 SIRT4 MRPS23 BCL2L1 BAD NAT8L MRPL24 MRPS33 CKMT2 MRPL28 MRPL41 ROMO1 SIRT5 MRPL53 HAX1 PRODH NDUFS7 MRPL51 SUOX PLEKHN1 NDUFV1 MRPL14 SCO2 MLXIP VDAC1 MRPS25 MRPL55 NME4 UQCRC1 LPIN1 HK2 TOMM40L COX5B SLC25A29 MCU MRPL9 TRAK1 MRPL21 AIFM2 MICU1 NDUFA8 NDUFS8 RHOT2 CPOX AURKAIP1 VDAC3 UQCRQ CIAPIN1 CPT1C TIMM44 FIS1 MRPS27 SFXN4 SFXN5 MRPL20 MRPL48 PI4KB NDUFB7 COX6B1 DNM1L MRPS26 IMMP2L COX17 CYP11A1 MTG2 ACSL5 CYB5B TOMM7 RTN4IP1 NDUFAF6 SFXN2 BMF MRPS16 UCP3 SPHK2 MRPL12 CRAT PARL MRPL43 OPA1 RSAD2 BAK1 MRPL2 TOMM40 TIMM10	up	*
GO_GLAND_DEVELOPMENT	0.0045964	0.0401543	0.4070179	0.2874889	1.390429	357	CPS1 CEACAM1 PRLR ONECUT2 ONECUT1 HNF1A TP63 EPHB3 CYP19A1 AK4 RPGRIP1L SOX2 TG SIX4 IQGAP3 E2F8 FOXE1 FA2H SIX1 MST1L TBX19 SLC6A3 SOX9 CCNB2 LSR TYMS UMPS XDH AACS CLCN2 TNC NME1 ITGA2 CLDN1 BTRC STRA6 TNFRSF11A SMARCC1 FOXA1 FRS2 MSX2 AURKA MAD1L1 MSX1 PRKDC WNT1 PKM MDK EGFR PLXNA1 SLC9A3R1 ASS1 OXTR AKT2 DDR1 CAD PML CCDC40 PTPN3 IGFBP5 GOT2 GNPNAT1 EZH2 EGF NF1 FADD SMO SEMA3A IGSF3 SRD5A1 STK11 IRF6 TBX1	up	*
GSE3982_MAST_CELL_VS_DC_DN	0.0055919	0.0464297	0.4070179	-0.2651123	-1.388090	166	GPD1 SLC31A2 SEMA6A KMO RBMS2 DCSTAMP LIPA SAMHD1 RASAL2 NUDT9 IL1RN DDO PILRA LRRFIP2 CD36 ARSB CYB5A ANPEP HLX TUBB6 CCL22 ATF3 CDS2 MATK CLIP4 ZNF706 RAB8B RAB31 GAS2L1 HK3 IRF8 NPR1 SORT1 MCUR1 KYNU ADAM10 CCNH RXRA VASH1 SCPEP1 ULK2 CD1E KIF1B ANXA11 C1orf115 RAP1GAP CTSH MAPK1 KCNJ1 OTUB2 FPR3 LAMP3 SCAF11	down	*
MIR302A_3P_MIR302B_3P_MIR302C_3P_MIR302D_3P	0.0014433	0.0167233	0.4550599	-0.2459598	-1.387899	303	RAB11FIP1 TMEM100 EDNRB FGD5 SOWAHC RDX TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 ZCCHC24 REST PDE8A NPAS3 ST7L CYP20A1 SHC4 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 SLC16A10 PLAG1 ARHGEF17 CFL2	down	*
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN	0.0001184	0.0022216	0.5384341	0.2724095	1.387880	894	TRIP13 FAM201A GALNT14 RUVBL1 AK4 GMDS BDH1 DEPTOR RPGRIP1L COIL TRNP1 DNAJC12 FLVCR1 MPP6 PDCD2L SLC2A1 CHST4 PLEKHH1 CCDC113 SORD ECE2 HILPDA TTC26 EBF3 ALDH18A1 SFXN1 KNOP1 UMPS EIF3B ACY1 MCM8 XPO5 COQ3 COX11 PVT1 WDR90 NUB1 NME1 RANBP1 CLPTM1L RUVBL2 BZW2 ZNF74 NOP9 DCBLD2 QTRT1 PUS7 NUP155 WDR3 MYO10 TMEM177 ATR SLC29A2 POLD2 TPR MPO CENPW DPCD ABCC5 TTLL12 RBM28 PDCD5 GCAT AKAP1 DUSP23 ANKMY1 SOX4 L3HYPDH ZNF530 FAM162A PSMG4 ZNF618 C7orf50 MAD2L1 FBL SLC25A39 DCTPP1 DNAAF3 TIMM50 HES6 AKT2 OXER1 ETFA RAD18 MRPS30 PHB ERCC2 ALG3 MGLL SLC25A10 HSPBP1 SPRY1 CCDC138 SKP2 DYRK2 PES1 GEMIN4 THOP1 TMED3 MRPL36 ISOC2 ANAPC5 HDGF UCK2 BCAS4 CCT3 GOT2 NPM3 DHX37 TRAP1 MCAT DHX33 GNPNAT1 FSBP POLR1C ACTR3B TNPO2 MRPS12 RNF207 TMEM120B ATAD3A NLN NOP2 LAPTM4B FGFR1OP STK11 PA2G4 ZNF692 RANGAP1 FAM86C1 NRGN HSPA4L MPI POLR2H SNRNP25 MYO19 TELO2 C19orf44 PDCD11 SCLY NDUFA11 PSMA5 TRMU C12orf45 MRPS34 DHODH TUBB2A PTGES2 SLC37A4 HMGN3 MORN2 COPS7B DPH2 ENAH MYBBP1A MSI2 ZNF816 GEMIN5 FZR1 MRPL4 PKP4 KIF20B NOC2L DNAJC11 CLTB RMND5B GEMIN6 CENPV PFAS TIMM13 GOLM1 L3MBTL2 KLHL23 DCUN1D5 CENPM RRP9 GPATCH4 POP7 FAM136A MRPS23 NOL6 SRRT MRPL24 PEX5 MRPL41 MED24 PRMT1 UTP20 TMEM147 NOC4L WDR35 HEATR1 LSM7 RABEPK CLUH LTV1 URB1 EXOSC5 CREB3L2 RNASET2 RCC1 TXNL4A AP4B1 ZDHHC11 MARCKS NEFH TSR1 PRMT5 STRBP NUP62 FARSA MRPL14 AGMAT ALMS1 RPS26 TM7SF3 SLC2A5 SCO2 DDX54 VDAC1 MRPS25 DOHH NME4 TUBGCP4 PDAP1 ABCF2 WDR4 WDR77 PRPF31 MLLT6 ATOX1 BMP8B N6AMT1 GADD45GIP1 CHMP1A MROH1 ZMYND19 ERGIC1 RDH10 MRPL21 LLPH SNRNP70 FAM118B LRG1 RHOT2 UBAP2L AURKAIP1 CIAPIN1 CLEC11A POLR1B SPR TCF3 POLR1A EARS2 ADAM15 ALG1 ANKS6 TBL3 PIGL ARMC10 SFXN4 DTD2 SLC35G1 PWP1 PPP2R5D DHRS9 RAD1 NDUFB7 RRS1 MRPS26 TMEM201 PPP1R14B ACTR5 ATP6V1E2 ACSL5 ALKBH2 TTC5 DAZAP1 STK33 FGFBP3 DHX57 MRTO4 SLC40A1 LUC7L3 RNF126 PM20D2 SRM C4orf48 PPARGC1B TRAFD1 MRPL12 DFFB	up	**
MARSON_BOUND_BY_FOXP3_STIMULATED	0.0000218	0.0005407	0.5756103	-0.2191558	-1.387646	795	SLC6A4 PECAM1 MNDA LPXN GPR65 DPYSL2 INSIG1 FYN EGR2 TMOD3 PPP4R1 BACH1 RTN3 CITED2 AQP9 SFR1 DYRK1A KBTBD3 NEDD9 TSHZ1 PSMD5 NFATC3 TLCD2 RCHY1 FGR RHOA DNAJB14 AVPI1 EDEM1 ARHGAP10 SH2B3 UBL3 RAP1A EIF5 TNIP3 SERINC1 ACOT2 PICALM CNTD1 KLF6 M1AP IFNK EIF4E FOXJ3 TOR1AIP1 HNRNPDL PPP1R13B SRGN EPM2AIP1 UBE2D3 TXN ARL11 MCL1 TIPARP EPB41L2 CCNI ROCK2 CSRNP1 ITPRIP PPT1 SCP2 SDCBP MEFV BNIP2 ITM2B COQ10B REST LEPROTL1 UHRF1BP1L ZFAND5 ZADH2 TMED5 LY96 SPAG9 CTSD ITIH5 ATL3 PTPRC KCTD20 PER1 MFSD11 SMAD7 EVI2A WFS1 PPP2R5A PEAK1 KPNA3 PLCD1 ADD1 CNOT6L MAPRE2 ARHGDIB ZNF426 SLC25A33 TCTE3 ZNF330 RBPJ ARL6IP5 ETF1 METAP1 WASF2 CDC40 PHTF2 SGK1 PSEN1 NEK7 RAB8B PIKFYVE HCST SRSF3 ETV3 ARL5B ARL6IP6 ETS1 OSBPL9 MAP4K4 JUNB RHOG PTGER4 FYTTD1 STX7 SKIL EEA1 GLIPR1 IRF8 LYRM1 HSPA13 GMFG HERC1 GYPC FAM43A CREB1 COBLL1 TMEM167B REL CAP1 TNFRSF9 DENND4A EPC2 LETM2 TOM1L2 NDUFV2 BLOC1S6 ACOT1 SLC3A2 SLC25A24 UBB CDK17 YTHDF3 RBKS ING3 ZFAND6 CCR4 NUP153 AKIRIN2 GSAP ZBTB1 JMJD6 TGIF1 TESK2 KCTD10 ABHD13 VAMP4 FEM1B ZBTB11-AS1 ZC3H12D PDCD1 PIM1 ATXN1 C8orf37 KCNA3 APLP2 CCR1 NPTN KANSL2 RGS2 GPR18 KAT2B ADAM10 TTC24 KTI12 MBNL1 FAM98B TCTEX1D4 RBL2 SESN1 MIER1 FKBP1A SEMA4A MTO1 ORMDL1 TAB2 GIMAP5 ZBTB25 ARIH1 DIXDC1 UBE2D1 ISCU PLGRKT NPAT LYSMD3 CUL3 CEPT1 ADORA2A CD3G GPR171 PAIP2 SAMSN1 SLC22A3 CCND3 NABP1 RAB2A USP48 DNAJA2 PPP1CB IRF2 CBX7 AFTPH UBE2V1 ATP6V0A1 MRPS28 USP4 TMEM50A CDKN1B UBXN8 DUSP6 TMEM30A CLIP1 FIP1L1 CENPC CX3CR1 LNPEP ITGAL DCUN1D3 TGOLN2 PDCD2 NCF1 DRAM2 HP1BP3 NDFIP1 DNAJB4 UBE2W DNAJC8 DAPP1 FBXW12 UBE2N BCL10 SGPP1 GABPB1 SLC25A40 STX16 PCMT1 FCGR3A ARHGEF12 TES CD3E ADH1B PNRC2 MAP3K1 SLC23A2 WDR26 TRAT1	down	***
GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_DN	0.0056984	0.0471156	0.4070179	-0.2649328	-1.387150	166	OLR1 CLDND1 CITED2 MEF2A DSCAML1 WBP4 USP47 IGSF6 IL23A CCNL1 WWC2 STARD4 ANXA5 CAV2 NDEL1 TXN PDGFA STAT5A SLC46A2 FAM76A MAFG NFKB1 ID2 CCND2 WASF3 PAFAH1B1 SACM1L MTPN SRF RPS6KA2 PDK4 CHDH PHTF2 SOCS3 PLEKHA3 MTMR14 HSPA1B DNLZ HELQ GYPC	down	*
GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_UP	0.0061589	0.0499715	0.4070179	-0.2662525	-1.386317	161	LYVE1 RAMP2 THBD LONRF1 YPEL5 B3GNT5 LHX6 NDEL1 MTMR6 TLE4 SGTB COQ10B ZNF24 FBXL3 DNTTIP2 BCLAF1 ANXA3 PI4K2A RASGEF1B TOPORS CREBRF ETF1 DCP1A PPP2CA PLEKHA3 MED30 MN1 FYTTD1 PNPLA8 HSPA13 KBTBD8 TMEM167B NUDT15 YTHDF3 ING3 ZRANB1 ABHD13 DPM1 MAP3K2 GABARAPL1 CRY1 GNA13 CLEC2B GTF2B SLC34A2 NUP98 B3GNT2 DNAJB9 TLK2 SAMSN1 RAB2A TBPL1 USP30 MZT1 FAM8A1 CYB5R2 IFIT5 SPTY2D1 LAMP3 TMEM11 ESCO1	down	*
GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN	0.0046621	0.0405343	0.4070179	-0.2618296	-1.385686	172	PTPRE FCER1A CORO1C GAS6 TEX2 DNASE1L3 MAN2B1 ADA SLC7A11 DACH1 LAIR1 IL18R1 GRN TXN CST3 ATP10A DUSP3 KIAA0513 ST3GAL2 DAB2 MGAT4A CD302 FCER1G ALOX5AP DSTN GNAQ TBC1D4 CRIM1 HEXB SERTAD2 KCNA5 PGD ST6GALNAC4 TYROBP IRF8 CDK2AP2 CRYM GRSF1 CD164 MYL12A SORT1 TCF4 DCK DUSP5 FCGRT ICAM1 LDLRAD4 SEC61B ALDH2 TMEM109 DAPK1 CTSC GPR171	down	*
MIR548AZ_3P	0.0003642	0.0057494	0.4984931	-0.2367382	-1.385564	419	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 KLHL8 MED4 QKI BMPR2 ARL8B PRKAR1A MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP MYO1B GPR85 CXXC4 PLEKHB2 N4BP2L1 UTP23 GNAQ TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 MED28 EBF2 NEK7 PIKFYVE HCFC2 RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 BMI1 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	**
PEDRIOLI_MIR31_TARGETS_DN	0.0008624	0.0113495	0.4772708	-0.2435424	-1.384703	340	SLC6A4 ANGPT4 HSPA12B ACE EDNRB USP12 SECISBP2L CD55 LYVE1 RAMP2 MMRN1 LDB2 DDX6 CDH13 MYD88 NCF2 TGFBR2 IL23A ARHGAP29 PKHD1L1 CNST SBDS TACC1 LATS2 CHRNE ABCG2 EMILIN2 LITAF KLF6 RNASE1 HLX SLC7A11 ZMYM6 MED26 CD93 LAMTOR3 FOXC2 SLC5A2 PPM1K AFAP1L1 ADAMTS9 CLDN5 CXCL2 IRAK2 N4BP2L1 GPR157 RUFY3 ANXA3 BACE1 VWF ZDHHC20 CLN8 PRCP PDK4 KANK1 RBPJ ARL6IP5 TMOD1 CREM VAT1 DESI2 ATXN1L SUGT1P3 DAPK2 ACKR3 KLHL18 IDNK CAP1 PDZD2 RASSF2 SPRY4 CWF19L2 CD164 ZFAND6 SMPDL3B GSAP SBF2 SOD2 DOK2 SPOCK2 CCL20 ICAM1 LDLRAD4 SLC31A1 OPN3 CHMP3 DCTN4 CDKN1C VPS4B EXD3	down	*
GO_NEGATIVE_REGULATION_OF_CELL_DEVELOPMENT	0.0032660	0.0311561	0.4317077	-0.2506353	-1.384700	258	SLC6A4 TNR DAB1 SEMA6B SEMA3G SEMA6A EDNRB DENND5A IL1B RAPGEF2 DDX6 CORO1C CTDSP1 RHOA SEMA6D MIR146A ASAP1 SEMA3B PAQR3 EIF4E PPP3CA WNT3A ARHGEF2 ZNF365 NODAL LRP4 PTPRO TRIM46 DAAM2 REST ID3 VIM ID2 PAFAH1B1 RUFY3 HES1 KREMEN1 GNRH1 SRGAP2C KANK1 MYLIP ID4 CNTF IL6 PSEN1 NOTCH1 CTSZ CNTN4 BAG5 IFRD1 LSM1 RTN4R TRAK2	down	*
SUPT20H_TARGET_GENES	0.0000195	0.0004934	0.5756103	0.2703183	1.384294	1123	RUVBL1 TICRR LYSMD1 PDCD6 BUB1B NUP107 ZNF84 ZNF12 C17orf75 PAGR1 NDC80 PHF14 TSFM MKS1 BRCA1 NOL12 PMS2CL POLE SAYSD1 FLAD1 TTC26 NUF2 YEATS4 IFT27 CDCA8 CENPA ACAD9 GPI WDR70 ACOT8 NBR2 FBXL19-AS1 CKLF-CMTM1 XRCC2 COPB2 MIS18A LIPE-AS1 DZANK1 LRRC27 UQCC1 LSM5 SPPL2B FAM220A NME1 TOP3B RANBP1 CEP250 CLPTM1L TMEM41A SMARCD3 RAB11B-AS1 DYRK1B BBS1 BOD1 KIF15 FBXW9 CCDC77 CENPL RFXANK IQCD NUP155 PSENEN POLA2 GTPBP3 CENPW COASY TPCN1 SPEF2 RBM28 NSUN2 RNU6-418P ERAL1 MRPL3 CMBL FANCD2 BLOC1S1 CCDC58 EMG1 TARS2 SLC2A11 FAM162A OAZ3 ZNHIT1 C7orf50 TRMT61B RAD51AP1 DCTPP1 ABCB9 ANKRD16 TRMT2A SPC24 B4GALT7 EEFSEC SPAG8 OGFOD2 RAD18 FBXL19 CNOT3 MNAT1 SRRM5 COQ9 CNPY2 SKP2 RECQL5 DDX56 CKLF RBAK ISOC2 CDKN2C HPS4 FRMD5 DDX51 ANAPC5 PABPN1 HDGF CDK12 SSBP1 PHF12 NPM3 STX18 VANGL2 WDR31 PRPF6 AP5Z1 PMEL BPGM DHX33 ENPP3 ANKRD26 FSBP TSPAN31 USP42 MTBP HMGXB3 PSMC4 RECQL4 CENPP WDR24 UNC45A CHCHD3 EFTUD2 GOLGA3 ZNF687 MZT2B ILF2 CCDC142 CDC23 VIPAS39 DCAKD WDR53 SPG7 FOXRED1 GALK2 TSNAXIP1 MTOR DNAJA3 AARSD1 RAD9A LONP1 PIGG HIRA TIGD6 CCDC130 FBXO15 COPS7B ADAR CENPQ RHBDD3 AKAP8L JMJD4 MRPL4 PDRG1 MTND5P11 STX18-AS1 ZSWIM3 DNAJC11 PRMT7 GFM2 GK5 FAM207A C12orf73 MAGOHB CEP128 PRRG2 CCDC159 ZBTB45 NAIF1 NIF3L1 CENPK KLC4 FAM71E1 EFCAB7 LSG1 PWWP2A VPS25 TMEM106B PALB2 STOML2 AAAS GBF1 FAF1 FBXO22 FAHD1 MRPS23 HMGB3P22 UBXN6 PPP6R1 MRPL24 MYPOP MRPL28 WDR83 RPL7L1 MED24 PRMT1 NOSIP NOC4L NMNAT1 LSM7 DDX23 SNAP47 MRPL53 RTEL1-TNFRSF6B SRSF1 HAX1 RAB3D C1orf109 LRCH4 STMN3 NDUFS7 KATNB1 DNAJC21 EXOSC5 YIPF2 POLR3E IGHMBP2 MED27 DDX55 TCERG1 MST1P2 COPZ1 DUS2 SPSB3 GTPBP10 PRMT5 LRRC14 ZNF580 AP2S1 NME1-NME2 AMN1 PRPF18 MCRS1 CYTH2 RPS26 RRNAD1 CCNA2 RBM42 RN7SL1 BANF1 ABCF3 RTEL1 DENR SCNM1 RNF121 MRPL55 ANAPC2 TMEM141 TXNL4B GTPBP2 CDK5RAP1 ABCF2 TTC31 WDR4 PRPF31 ACSF3 NUBP2 BMS1 N6AMT1 TTC1 TRIP4 NBR1 SEC13 PFKM GTF3C5 MRPL9 MRPL21 RPUSD2 RPRD2 VPS9D1 ACP1 AGBL5 TMEM101 NUBPL AURKAIP1 RBM19 ZNF131 CIAPIN1 TCF3 POP4 SMPD4 ZMAT2 NDOR1 ALG1 LRSAM1 NMT1 TRUB1 SNRPC TBL3 PIGL FBXO45 FAM185A CDKAL1 MRPL20 PWP1 DCAF11 TMEM38A RAD1 MRPL48 NAT10 TK2 TTLL5 TRUB2 FAM222B MOK DDX41 BRIX1 TRAPPC6A ANKRD11 SLC33A1 COPE KIAA0586 INO80B CEP290 EIF2D HEXIM2 RPL23A MRTO4 BMF DHDDS TMEM63C PPP1R13L MAN2C1 SPHK2 METTL4 C12orf43 RAB40C RANBP10 TMEM259 RPL36 ZC3HC1 TBC1D10B ZNF276 ROPN1L ABHD2 TNPO3 NFE2L1 OPA1 AP2B1 SAFB TMEM9 NSL1 ZKSCAN4 MRPL2 TOMM40 MCEE MAD2L1BP SLC4A1AP CTU2 SRFBP1 GLRX5 ZNF77 TEFM PRCC RPS6KB2 SAFB2 ARMC6 CXXC1 SLC27A5 CACTIN EHMT1 AP2A1 CCDC86 XRCC5 PLOD3 TXN2 CMTM3 VWA5A LRPPRC FAM149B1 SLC7A6OS C1orf74 TIMM9 DYNLT1 E2F4 PPP2R1A NUDCD1 STRIP1 ZNF17 INTS9 DHX38 KMT2D C5orf49 EVI5L NUP214 DDX49 SUGP2 PTPN23 COQ4 SMC4 IPO4 GTPBP4 METTL9 BECN1 TMEM183A EEF1D SNHG10 SKA3 TMEM203 IK HNRNPA1 ABCB8 CDC5L KLHL20 GTF3A KHSRP BUB3 DNAJC2 SLC39A3 USP19 DCTN5 CIC MRPL13 DARS2 CLPB NVL HNRNPUL1 AHCYL2 ZC3H3 PET100 JRK IFT74 BCKDHA DAGLB ENSA REXO4 COX16 VTI1A KANSL1 DDX19A EMC10 ZBTB17 ITGB3BP BLOC1S3 WDR92 MAPKAPK5 CRTC2 CPSF1 MLST8 TSKU P4HA3 MT-RNR1 IMMP1L DRG2	up	***
MARTINEZ_RB1_AND_TP53_TARGETS_UP	0.0001109	0.0021072	0.5384341	-0.2320819	-1.384083	509	SLC6A4 GPD1 WEE1 EPAS1 EREG HSPB7 PECAM1 LRRC8C FABP4 MNDA CAT USHBP1 EMP2 CYP4B1 LIPA RAMP2 CDH5 ARRDC4 LPL HSD17B11 CD44 BAG4 QKI SLC25A30 ARL8B MSRA MEF2A ALAS1 NR3C1 TGFBR3 NCF2 FUCA1 TGFBR2 TRIB1 PILRA SPCS3 GINM1 TXNIP CD36 STARD4 CLCF1 BMP1 BZW1 PRELP RANBP9 NLK LITAF HDC ZNF410 HIPK3 CAV2 LCP1 SERPINB9 STOM PPP3CA NR4A1 SIRPA RGCC IL18R1 SPTBN1 SRGN TCAP UBE2D3 TFRC PDGFA HIF3A MSR1 CFD SORBS1 LIMS1 ST3GAL2 PRKD3 DRAM1 THBS1 CLDN5 ITIH5 CDKN1A RBMS1 ATF3 CTBS CCND2 TM6SF1 DUSP1 ALOX5AP WDR48 PINK1 HLA-DQA1 ADD1 MAPRE2 TGFB2 PDK4 ZNF330 SPIN1 RBP7 HCAR3 SAR1A NSMAF ESD RAB31 SLC14A1 TYROBP RABGAP1 JAK1 PRKCE MORC3 TPP2 IP6K1 CELF2 ACSL1 MOB1A FOS UBB PNPLA2 KLB CD74 CPA3 SORT1 ZNF521 CHPT1 PEA15 ITGA9 SERPINB1 HBP1 GNA13 SERINC3 MR1 TSPO PCCA SOD3 ARPP19 RXRA CCL20 AMD1 PDLIM5 DCTN4 RTN4 PIP4K2A MFAP5 CALCOCO2 NSUN4 ACTB HAVCR2 PSME4 PLGRKT TMEM109	down	**
AML1_01	0.0029786	0.0289750	0.4317077	-0.2508879	-1.383784	238	GPD1 DAB1 SLC12A6 CD101 EGR2 LMO2 RASAL2 CORO1C SLC15A3 CBL IL23A CYP17A1 UBL3 ENTPD1 SWT1 PICALM LUZP1 HLX GPBP1L1 ZBTB8A NR4A1 ARHGEF2 DIABLO FLI1 MOAP1 ID3 GRK5 MPL CADM1 PDE3B VIM FRMD4A XCL2 FCER1G TBX5 ADAMTS8 MIR17HG CRTAC1 FOXN3 SCEL CREM BCAR3 RGS18 PSMA1 CELF1 MSRB3 ATP6V0B RHOG GRASP SNX1 CAP1	down	*
AML1_Q6	0.0029786	0.0289750	0.4317077	-0.2508879	-1.383784	238	GPD1 DAB1 SLC12A6 CD101 EGR2 LMO2 RASAL2 CORO1C SLC15A3 CBL IL23A CYP17A1 UBL3 ENTPD1 SWT1 PICALM LUZP1 HLX GPBP1L1 ZBTB8A NR4A1 ARHGEF2 DIABLO FLI1 MOAP1 ID3 GRK5 MPL CADM1 PDE3B VIM FRMD4A XCL2 FCER1G TBX5 ADAMTS8 MIR17HG CRTAC1 FOXN3 SCEL CREM BCAR3 RGS18 PSMA1 CELF1 MSRB3 ATP6V0B RHOG GRASP SNX1 CAP1	down	*
GO_REGULATION_OF_RESPONSE_TO_BIOTIC_STIMULUS	0.0002076	0.0035367	0.5188481	-0.2375723	-1.383770	417	SIGLEC11 NLRC4 EREG CD300LF SASH1 FCN1 SCIMP SIGLEC16 PPARG CD55 PGC IL1B MNDA FYN LY86 SAMHD1 CLEC12B CAV1 MYD88 CLEC10A RBM14 MARCO OTUD4 PSMD5 LAMP1 TRIB1 RFTN1 IL23A FGR CD36 MIR146A CARD16 CLEC7A TNIP3 RNF125 FOXP1 IFNK SERPINB9 TRAF6 GRN CRK CRTAM UBE2D3 BIRC2 SLC46A2 LY96 UBQLN1 NFKB1 CADM1 IRAK2 TLR4 SFTPD FCER1G ZMPSTE24 PIAS1 HCK MUC3A CD160 CTSS SOCS3 APPL1 SEC14L1 PSMA1 CARD8 HSPA1B IFNGR1 JAK1 PRKCE MALT1 UNC13B PRKACA PLCG2 UBB PELI1 YTHDF3 PSMD12 ICAM2 TREX1 CR1 PIK3AP1 SMPDL3B AP1G1 CD1D FPR2 YTHDF2 NLRP6 PIK3C3 CNOT7 KLRC4-KLRK1 IFNLR1 SYT11 IL18RAP ARRB2 RTN4 TAB2 RIPK2 UBE2D1 HAVCR2 PSME4 CREBBP ICAM3 TLR10 SIN3A NFKBIA PAK2 KLRK1 AIM2 ITCH PSMD6 PSMD9 SFPQ PUM1	down	**
GO_CELLULAR_RESPONSE_TO_HORMONE_STIMULUS	0.0002070	0.0035330	0.5188481	-0.2285843	-1.383293	542	HCRTR1 ZNF366 RAMP3 LPIN2 PPARG ADTRP CPEB2 IL1B LHCGR ADCY9 RDX ADCY4 PTPRE RAMP2 PID1 KL PCSK9 FYN LPL LMO2 INPP5K CAV1 BAIAP2 CRY2 VAMP2 PRKAR1A RXFP1 NR3C1 CASP9 RHOA ANXA1 SSTR1 ATP2B1 LATS2 ANXA5 FOXP1 CAV2 ADIPOR1 EIF4E NR4A1 RB1 NFE2L2 NDEL1 CRK SFRP1 KANK2 HNRNPU ATP6V1H ATP6V1B2 FOXC2 NODAL IL10 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 REST KLF9 ROCK1 DAB2 ARNTL SOCS2 ATP6V1D NFKB1 PDE3B NR1D2 SIK2 ATP6V0D2 IGFBP2 LBH PER1 DUSP1 PIK3C2A INHBA ADIPOR2 GNAQ GNAI2 TBC1D4 NCOA1 PIAS1 PRCP SLC25A33 PDK4 UFM1 KANK1 MYO1C FAM107A CREBRF ADCY2 CTSS SOCS3 APPL1 RAB8B RWDD1 JUN NOTCH1 RAB31 USO1 GAS2L1 DDX17 ATP6V0B JUNB DNAJA1 PTGER4 PIK3R1 DDX5 PRKCE GRB2 CREB1 PTGER2 RAB8A MT-ND3 PRKACA EGLN2 ACSL1 FOS ATP6V0D1 RHOQ FOXO3 FOSB DDX18 HNRNPD NR2C1 TGFB1I1 ATP6V1A IRS2 ATP6V0C WBP2 CRY1 GATA6 ACTN2 KAT2B RXRA JUND NR2E3 ICAM1	down	**
GSE12366_NAIVE_VS_MEMORY_BCELL_DN	0.0046621	0.0405343	0.4070179	-0.2613762	-1.383286	172	WEE1 MS4A7 RDX BTNL9 FOLR1 GFOD1 NAAA PAG1 SRGN PDE4D CD58 TBC1D9 AHNAK DGKE KCNMA1 PTAFR ARNTL MGAT4A VIM PAPSS1 ALOX5AP PLEK CLIP4 CALM2 EMP3 CD80 VPS37A PHACTR2 TIGD3 IL2RB GPR183 ENTPD4 APH1B ACSL1 TSC22D1 NAB1 ATXN1 CD81 CCR1 KYNU TRAC SLC35D2 ITPRIPL2 CALHM2 IER5 CDC42EP3 PTCH1 SCPEP1 TRAF1 SAMSN1 RORA NABP1 HERPUD1 CRTAP CTSH BHLHE41 CLIP1 PRKCH ITGB1	down	*
GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_UP	0.0047142	0.0408360	0.4070179	-0.2612824	-1.382790	172	GPD1 RBMS2 RAPGEF2 GPC5 ARHGEF15 SNX32 CTSW BMPR2 ELF2 YPEL5 MEF2A SPATA1 RFTN1 DNAJB14 SEMA6D GM2A RAB33B EPB41L2 CCNI AFAP1L1 FBXL3 FMNL3 ST7L HOPX SMAD7 PI4K2A AFF3 CREBRF COPS2 HMBOX1 C20orf194 USO1 MAP4K4 OSTM1 IFNGR1 ZBTB24 CGGBP1 YPEL2 ZFAND6 HBP1 C8orf37 STON1 TSPO	down	*
MIR543	0.0010411	0.0131091	0.4550599	-0.2504227	-1.382379	278	EREG AKAP5 IL1A MRPS18C ST6GALNAC3 ZBTB34 OTUD1 RASAL2 QKI AKAP7 GPCPD1 SRSF7 C5AR1 NR3C1 TEX2 HEG1 LIFR EIF1 FZD4 KLF6 SLC7A11 DACH1 TCF7L2 ATP10A MSR1 PER3 TBC1D9 KCNMA1 YBX3 GAPVD1 NR1D2 AQP4 ARHGEF26 CD302 ZBTB43 PEAK1 CYP26B1 IKZF5 PIAS1 C2orf69 GPBP1 CREBRF FMNL2 DCP1A ID4 METAP1 COPS2 HECA RASSF10 PDE5A DHX15 EEA1 THUMPD1 FRYL CREB1 SLC10A7 ZNF597 PREX2 CGGBP1 BCL6B PKD2 MARC2 IRF5 GOLGA8R BAZ2B ABHD13 GOLGA8H PPP3R1 BMP2K CTTNBP2NL CYB5R4 TBC1D1 CTSC PRKG1 C21orf91 RORA CNTNAP3B FAM13B EIF4A2 RNF13 RABGEF1 DMXL2 YTHDC1 PSIP1 ACVR1C PLAG1 CHML CCDC112 MAPK1 CLOCK ING1 C16orf95 SH3GLB1 PLXDC2 ATP1B1 PRTG TRPM7 UBE2W SPTY2D1 GOLGA8B	down	*
GO_REPRODUCTION	0.0000619	0.0012940	0.5384341	0.2707800	1.382158	1006	TSPAN8 SYT8 PRLR TRIP13 TP63 ABCC2 BRINP1 SPATA24 SPATA25 MYCBPAP FOXA3 BIK PPP1R1B CYP19A1 RUVBL1 PMFBP1 FBXW8 SPINK13 BUB1B NUP107 NEK2 CCNB1 WFDC2 NPAS1 MND1 DPY19L2P1 SLC2A1 CLGN SORD GAL3ST1 CREB3L4 SIX4 ZP3 TTK RACGAP1 LHB E2F8 CATSPERB SLC26A8 SPP1 ASPM EIF2B5 TTC26 PLK1 NUF2 IFT27 PTTG1 ESPL1 B4GALNT1 SOX9 FIGNL1 STC2 RBBP8 CYP27B1 SPINT2 RAD54B CDC25A UMPS XRCC2 NOX5 CCNF APOL2 SPINK1 CIB1 TDRKH MCM8 MAP2K6 SRPK1 INSRR NCAPD2 CCT2 TNC DNAI1 RSPH1 ITGA2 ZSCAN2 OSBP2 CASP2 EXO1 NUDT1 STRA6 DLG1 SMARCC1 SOX30 STAG3 RPL39L FOXA1 SPAG16 DPY19L2P2 CUL7 FBXO43 FOXJ1 TSGA10 FRS2 PAFAH1B3 BUB1 FANCA MSX2 TOP2A IDO1 CCT5 AURKA EME1 AGT REC8 ODF2 SYCP2 VASH2 MSX1 POC1A IL12B DPCD MDFI PRKDC SPEF2 RHOBTB3 TEKT2 SGPL1 PCDHGA4 NSUN2 HOOK1 RAD54L FANCD2 PLTP WDR66 HORMAD1 CDC25C ANG MDK NME5 EGFR OAZ3 EME2 CGB7 SPINT1 HSF2BP GAS8 RAB13 MST1R OXTR DNAH11 BRIP1 DDR1 CAD GNPDA1 SPAG8 PTGDR2 GRHL2 CCDC136 ALDOA CCDC40 BMP5 MEA1 IGFBP5 ASF1B LRGUK LRRC6 CDK1 LRP2 MERTK PICK1 CCT3 GOT2 SUN1 E2F1 ITGB8 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 SEMA3A DNAH5 TCTE1 RTCB ACVR1B SRD5A1 STK11 LGR5 GOLGA3 FANCG CATSPERG CCNE1 ST14 PABPC1L CATSPER3 NPHP1 TUBG1 VIPAS39 GGT2 TSNAXIP1 ADNP MTOR CTSV MNS1 ADAM28 DHODH RAD51D IQCG MORN2 UBE2Q1 PCSK4 GAS2 FZR1 TSSK3 SPAG1 MMP7 TEKT3 TAC4 SPA17 PRMT7 SPATA32 SLC4A2 KRT19 GNRH2 CHD5 THRB ESR1 TYRO3 SLX4 CCT7 RAD50 NR6A1 KDM3A ANKRD31 EPN1 KLHDC3 PTN MEI1 CDC20 ROPN1B TUBG2 AAAS BCL2L1 CATSPER2 RPA1 BAD TFCP2L1 FANCM KRT8 DNMT3A	up	**
H1_6_TARGET_GENES	0.0047675	0.0411662	0.4070179	0.2832683	1.380476	390	CEACAM1 MROH3P FOXM1 SLC2A1-AS1 HOXB-AS3 IGSF9 GPT WFDC3 GMDS SLC13A3 TFAP2A SLFN13 NEK2 IQCE SLC2A1 TTC39A LRRC37A3 DNMT3B ZNF283 KIAA0895 EPS8L1 C1orf220 NOS1AP SMARCD3 C19orf48 OSBPL2 SYTL2 RHNO1 EEF1E1 AURKA C1orf226 LPIN3 LIPE WDHD1 ZNF146 ANKRD13B SNHG11 B3GNTL1 LIG1 SRD5A3-AS1 EHHADH AKT2 LRRC61 B4GALT7 GEMIN7 DDR1 PPP5C SRRM5 TULP3 AFAP1L2 APLP1 SUPT5H CROCC DNTTIP1 PACS1 STX18 MAP3K10 ACTR3C LARP1 CPNE1 CCDC88C COA4 PPP1R36 C9orf43 ACBD6 CATSPERG OVOL3 AKR1E2 COL1A1 TUBG1 SEC16B C19orf47 SPG7 ALDH7A1 COPS7B ZNF234 PPOX RHBDD3 ANP32E STX18-AS1 LAMTOR2 CDK13 PRRG2 ZBTB45 ZBTB7B PROX1 FAM71E1 KCNB1 CA11 BLCAP CYP2S1 NOSIP TMEM147 GNG4 ZNF783 C1orf56 RTEL1-TNFRSF6B STMN3 IGHMBP2 SLC1A5 ABCD4 WDR27 ZNF780A CNTN2 NUP62 AP2S1 CYTH2 RBM42 ECH1 RTEL1 INO80E MARK4 ZSCAN22 MRPL21 SNRNP70 ZNF573 AURKAIP1 GNA12 RNF213	up	*
GO_LATE_ENDOSOME	0.0033425	0.0317442	0.4317077	-0.2529372	-1.380367	217	SLC31A2 MCOLN1 OSBPL11 OSBPL1A RAPGEF2 PCSK9 FIG4 NEDD4L ARL8B LAMP1 SLC11A1 RILP RAP1A CHMP1B LITAF CYB561A3 ABHD6 GRN LAMTOR3 RAB14 RHOB CDIP1 MVB12B M6PR SFTPD WDR48 HTT VAMP5 BACE1 RASGEF1B VPS37A CTSS MAGI2 PIKFYVE SFTPB OSBPL9 STX7 UVRAG CLN3 CST7 TMEM192 CD74 SFTPC TMEM230 IFNAR1 PIK3C3 ANKRD13A VPS39 UNC13D SLC31A1 CHMP3 PARM1 TPT1 CXCR4 VPS4B GIMAP5 CD1E MCOLN2 MMD LDLR RNF13 CTSH SPPL2A MAPK1 EXOC8 VPS36 CHMP4A LAMP3 SNX14 HLA-DRB1 LAMTOR5 KIDINS220	down	*
KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_DN	0.0056906	0.0470661	0.4070179	-0.2595712	-1.380272	176	SLPI HHEX IL1B HSD17B11 LY86 WDR74 NEDD4L AQP9 VAMP2 PLEKHA1 INPP5A CD22 GGA2 SH2B3 SLC7A7 TM2D3 ABCG1 FOXP1 ZYG11B RHOB ARRB1 KLF4 RRM2B TJP1 LAPTM5 CADM1 NR1D2 NKIRAS1 SELL PNRC1 CCND2 PER1 SMAD7 IL7R WASF2 RNF141 NECAP1 SLC3A2 GPR3 RIN2 IRF5 TCF4 SBF2 TSC22D1 FEM1B PIM1 CCR1 PDE4B JUND CCR6	down	*
MIR133A_3P_MIR133B	0.0058631	0.0480887	0.4070179	-0.2551767	-1.379986	202	COL25A1 OSBPL11 EMP2 OSCAR TMEM170B STXBP6 FUCA1 PSMD5 FAM49A EDEM1 EIF4A1 SGMS2 PEX5L GPM6A ARRB1 SGTB PTPRO RUNX1T1 KCTD20 DUSP1 PEAK1 CMTM6 PTH1R SACM1L RBPJ PPP2CA WASF2 PDIK1L SGK1 EBF2 TRIM55 PLEKHA3 C11orf58 SP3 CAP1 TAGLN2 SNRK TMEM128 YPEL2 PPP2CB NUP153 MMP15 PCDH17 GNB4 GABARAPL1 ANKRD12 BNIP3L YAF2 SEC61B ARPC5 B3GNT2 THRAP3 NUP160 CNN2 ELFN1 DMXL2 AFTPH RBMXL1 TBPL1 SLC25A38 CMPK1 FTL RB1CC1 CSNK1G3 FAM160B1 ZNF362 SGPP1	down	*
ZNF654_TARGET_GENES	0.0000094	0.0002654	0.5933255	0.2681426	1.379537	1377	CPNE4 IGLV4-69 DKK1 UNC5CL PRLR STYK1 GPR156 DDX11 ENTPD2 MEGF10 SPICE1 SPATA24 EPHB3 EGLN3 MDM1 IGSF9 SPOCK1 DNAH2 MCM10 C1QTNF6 PMFBP1 TFAP2A S100A2 BUB1B TMEM51-AS1 SYNPR IGLV1-36 COIL ADRA2A DOC2A POLQ TM4SF18 FAM177B NPAS1 SEMA4B SCN3A MND1 COL27A1 SLC2A1 TSFM PRIM2 TTC39A PLEKHH1 SDK2 C6orf141 EFNA3 CDK4 ASIC1 XKR9 ALDH1L1 CABIN1 L3MBTL1 PCDHGA1 CEP70 CHRNA7 BAIAP2L1 EFNA4 AURKB ECT2 ESPL1 CUEDC1 RGS6 GRIN2A CDC6 TFDP2 VSTM2L ZNF221 C4orf19 AGR2 SPATS2 SPINT2 LSR XPNPEP1 ANKRD36B CLCN2 KHDC1 ZNF3 LIPE-AS1 ARHGAP40 GINS4 VILL B4GALT4 EPHB1 DZANK1 CDK5RAP3 AP1G2 SLC4A8 UQCC1 TRIM45 LSM5 NUB1 TAMM41 FAM220A SYT12 NME1 OSBP2 TNNT2 LTB4R2 SMARCD3 NLE1 FOXA1 BCYRN1 RND2 DCBLD2 RNF216P1 FSIP2 AUNIP TOP2A GPER1 BPHL SPTB NDUFS2 METTL7B TPR IL12B DPCD C1RL LPIN3 SPEF2 RBM28 RNF43 SGPL1 FNDC5 DUSP23 CCDC114 FHOD3 WDR73 WDR66 XXYLT1 LETMD1 SARS2 ARMC12 HEBP2 ABCB6 ZNF786 RAB13 DCTPP1 THAP10 DNAAF3 OXTR MRPS11 IPO9 TRGV1 FBXL19 INPP4B PHB FAM157A SLC18B1 SYMPK HOXB5 TSHR FBXO16 RGS4 ALDOA IGLV1-40 NRG4 ALG3 MGLL MGAT4B UQCR11 KCNJ2 GPX8 IKBKB RNF216 NUSAP1 MB ASF1B C2orf50 DNER SLC39A11 DMKN CDK12 LINGO1 CLMN EXOSC2 TNFRSF21 BCAS4 SSUH2 ARPC1A ZSCAN25 TNK2 GDPD1 OAT SYN3 CCNJL LRRC9 MRPL17 FAM98C RUFY4 GNPNAT1 SDCBP2 ENPP3 KLHDC9 NEK5 CCDC88C NUP205 POC1B MRPS12 PLCG1 ARTN TMEM120B RNF150 SNRPE TMEM51 ABCA4 NOP2 PCDHGA2 KLHL22 MAST1 CPT1B ANXA2R UNC45A TPD52L2 EFTUD2 TBX1 GIPC1 MZT2A ZNF354A CATSPERG GRAMD1A SPEF1 CAPS2 INTS7 ZGPAT ARFRP1 CCDC142 RHOC COL1A1 CDK3 IGLV6-57 NADK2 SEC16B VPS41 DNAH7 ADNP TACC3 MLF2 DHRS4-AS1 COL9A2 RAD9A C19orf12 SLC37A4 MRPL11 RAD51D UBE3D RGS22 SUDS3 ARF5 ACBD4 UBE2Q1 TMTC2 POMT2 HM13-IT1 CSNK1G1 MEGF8 SOX2-OT LMTK2 SRGAP1 ATG9B PDRG1 GRIN3B TJAP1 SPAG1 XPR1 DAP3 LRWD1 IGLV1-47 SYNGAP1 TSEN54 ZNF282 EPB41L4B FLG-AS1 TYRO3 PEX10 ZBTB45 ENC1 TMEM232 ELAC2 DNAJB13 YARS2 ARHGAP12 NR6A1 BAZ2A P4HA1 KLC4 TMEM234 STRN4 LINC00910 KCNB1 COG1 DGKA ANKRD6 AHCYL1 OLFML3 RIN1 AAAS CA11 FTCD ASB6 SIRT4 MAN2A1 ZNF616 NRXN2 RRP9 AP3M2 SLC6A1 POP7 BCL2L1 FITM2 NOL6 PELO CDK5RAP2 KRT8 PEX5 TTC34 DYNC1LI2 WDR83 MED24 PRMT1 DHX8 RNF215 KPTN NMNAT1 DDX23 ADD3 HAX1 EDAR POLR3E SUOX RCC1 RSPH4A SMARCC2 ANK3 GAD1 SF3A2 ADAMTS17 ZNF274 TCERG1 COPZ1 PRMT5 CNTN2 IL12A CEP85 NME1-NME2 B9D1 ZNF212 ENGASE TMEM117 RPL5P11 DENR POLR3B SCNM1 PCBD2 ICK CLUAP1 HOOK2 CCDC88B TTC1 TOMM40L ATG4D PPP6R2 LRRC71 GRAMD1B OXCT1 MLLT1 TYSND1 SNX19 POMK ZNF610 DIP2B SNUPN RBM19 BCAS3 GOSR1 RASGRF1 RPP25L ADRM1 ADAM15 POP4 TRIB2 CGN NPTX1 ALG1 TP53 PDZD7 ZNF341 ALOX15 TIMM44 FBXO34 IDUA MRPS27 SLC36A1 NNMT LINC00205 TAF4 LRRC4C TMEM98 ZMYND10 RAD1 SPATA20 RRS1 NLGN1 KHNYN SH3GL1 CLASP1 ATG4B MOK COL16A1 ACAD8 ANKRD11 PCTP ALKBH2 CLNS1A TPM1 F5 GLIPR1L1 DAZAP1 UNC119 KCNH4 NDUFAF6 EIF2D STK33 VPS18 ZNF511 EID2 DNAAF1 SEC31B ST8SIA1 SCRN2 ARSG SHQ1 MAN2C1 VPS16 ITGB5 CRYGS PDK2 SH3RF2 UBAP1L NAT1 PRPF19 PARL DSN1 COMTD1 ADSL RPL36 HDAC10 RBL1	up	***
MIR548D_3P	0.0001282	0.0023764	0.5188481	-0.2314493	-1.378534	518	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 PAG1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A SCP2 LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 ZBTB43 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 N4BP2L2 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA NABP1 SFPQ	down	**
GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN	0.0061245	0.0497709	0.4070179	-0.2632830	-1.378512	166	LPIN2 CD55 PLA2G10 CITED2 PLEKHA1 SLC15A3 FBXO3 FUCA1 IER2 KIAA0355 CACNA2D2 TMEM204 TOR1AIP1 ZMYM6 RGCC EVI2B KLF7 TMBIM1 NFKB1 P2RY2 CLK4 CD53 EVI2A PPP2R5A MMP19 TMEM9B MYLIP ARL6IP5 OSTM1 ARHGEF10 JAK1 GPR183 RASSF2 APH1B SNRK RRAS BIN2 APBB1 RPL21 SPOCK2 MEGF6 KAT2B CLEC2B PDE4B SLC35D2 ULK2 NEK3 FNBP4 CAMSAP2 GSG1 GRB10 FADS3 AKTIP TGOLN2 FTL FXYD5 ZNF14 SERP1 STX16 KCNAB2 CSF3	down	*
DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN	0.0003567	0.0056490	0.4984931	-0.2351478	-1.378454	424	DLC1 DENND5A RAPGEF2 RCOR1 BDNF FYN KIAA1109 QKI SRSF7 DYRK1A NR3C1 RFTN1 HEG1 NUMB ARHGAP29 ATP2B1 UBL3 PBX3 PICALM REV3L KLF10 KLF6 EIF4E PPP2R2A FOXJ3 RB1 HNRNPDL ITSN2 TCF7L2 TIPARP ZMIZ1 ADARB1 PTPN12 ROCK2 TLE4 ACSL3 SOCS5 KLF7 MYO1B GAPVD1 SEC24B PDE8A RBMS1 CDS2 EPS15 CCSER2 WASF3 DUSP1 MBD2 PPP2R5C GNAQ OXSR1 IL7R PAFAH1B1 KPNA3 TP53BP2 AFF1 CRIM1 MARK3 NCOA1 TGFB2 STK24 TDRD7 FOXN3 RAB6A RBM39 RBPJ PPP2CA BCAR3 NEK7 PIKFYVE SEC14L1 SRSF3 C2CD2 JUN RABGAP1 FERMT2 DHX15 IPO7 ZNF804A FRYL CREB1 HOMER1 UVRAG TUBGCP3 WDR7 CDK17 HIVEP2 FOXO3 PKD2 SPOP NUP153 PHF3 BAZ2B ZFYVE9 PIK3C3 NFYC ORC2 CRY1 ADAM10 PHLPP2 MBNL1 ATAD2B HELZ FGF2 CEP170 NBN TIAM1 PIP4K2A TRAPPC8 EPHA4 TAB2 SIK3 ARIH1 NUP98 CREBBP DAPK1 LIMCH1 GTF2F2 PTEN TLK2 CAMSAP2 NRG1 TLK1 PUM1 RNF13 EVI5 ABI1 STARD13 UBR2 SERPINE1 CLIP1 ATP11B ATF2 LHFPL2 CLOCK	down	**
GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN	0.0049747	0.0425882	0.4070179	-0.2604280	-1.378268	172	SLC31A2 SC5D SGK3 QKI FRAT1 GGA2 SLC7A7 MAP3K8 IL18R1 TNS1 GLDN IL10 MOAP1 DUSP3 DAAM2 ZADH2 RMDN3 PLEKHB2 PER1 DUSP1 PIK3C2A N4BP1 PIK3R5 TOPORS LACC1 PDK4 MAML2 HECA STX7 SNX1 RASSF2 PELI1 SIGLEC1 YPEL2 AZI2 YTHDF3 BIN2 VAV3 TAGAP STK40 PLEKHO2 CSNK2A2 ETS2 RLF TFPI PSME4 SSH2 GLUL RNF38 SKI THRAP3 SAMSN1 SLC16A10 STARD13 C1QB ZBTB16	down	*
GO_NEGATIVE_REGULATION_OF_CELL_CYCLE	0.0022299	0.0232639	0.4317077	0.2771998	1.378029	530	HMGA2 TRIP13 FOXM1 BRINP1 MDM1 CDC45 TICRR CHEK2 BUB1B NEK2 CCNB1 SOX2 CENPF TIMELESS NDC80 TBRG4 BRCA1 TTK CDK4 BRSK1 E2F8 GTSE1 NABP2 PLK1 AURKB PTTG1 ESPL1 CDC6 TFDP2 RBBP8 ORC1 CCNF DTL MAP2K6 ZFYVE19 ZWINT CDT1 CDK5RAP3 SPDL1 CASP2 DLG1 NLE1 TP53BP1 FBXO43 KNTC1 RHNO1 BUB1 TOP2A GPER1 AURKA EME1 CBX3 ATR TPR MAD1L1 CLSPN IL12B RRM2 PRKDC NSUN2 TOM1L1 HORMAD1 CDC25C SOX4 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 SOX11 MDM2 AKT2 MGA BRIP1 BLM PML CNOT3 PTPN3 CDKN2C CBX5 ING4 CTDSP2 CDK1 RFWD3 GMNN E2F1 PSMB5 DNA2 EZH2 CNOT11 TAF6 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 STK11 IRF6 CEP63 INTS7 CNOT2 PSMA5 MTOR RAD9A PSME2 TRIM37 FBXO4 MYBBP1A GAS2 FZR1 CGREF1 KIF20B LAMTOR2 SGSM3 PSMD2 CDC7 PROX1 L3MBTL2 PSMB3 CDC20 BCL2L1 CHMP4C WNT10B CDK5RAP2 THOC5	up	*
LEE_BMP2_TARGETS_DN	0.0004911	0.0072451	0.4772708	0.2713464	1.376815	801	SHISA3 TRIP13 FGA MEX3A HELLS RUVBL1 AK4 CDC45 MCM10 BHMT NGEF NUP107 FLVCR1 CPSF6 PSPH TTF2 TBRG4 BRCA1 PHGDH CDCA7 THEM5 TTK GINS1 E2F8 TRAIP GMPS BAMBI IGSF11 CDC6 E2F3 FIGNL1 UHRF1 KNOP1 MCM4 MCM2 CDC25A UMPS COL22A1 DTL CCT6A XPO5 MIS18A SRPK1 SHMT2 XPOT ZWINT CDT1 AOC1 SPDL1 SIMC1 KAZALD1 NME1 HAUS5 RANBP1 TTLL4 RUVBL2 MELK DNPH1 EXO1 CISD1 NLE1 BUB1 FANCA EEF1E1 AURKA NUP155 WDR3 MCM7 CENPW CLSPN RRM2 MMS22L WDHD1 NSUN2 MCM3 CHAF1B PFN2 TARS2 SMYD5 TOPBP1 CHEK1 ASS1 ORC6 ACTL6A MAD2L1 CSRNP2 RAD51AP1 DCTPP1 PRMT6 CAD BLM NIPAL1 ALG3 SKP2 PARP1 DDX56 GEMIN4 THOP1 CKS1B CXCL14 DDX51 ASF1B POLE2 MCTP2 UCK2 CCT3 C1orf112 ATIC DCBLD1 GMNN GTF2E1 POLR3K UNG KCTD13 STEAP1 PRRX2 L2HGDH DNA2 MRPS2 SLC25A13 DHX33 PSAT1 ANKRD26 LARP1 FEN1 EZH2 NUP205 SF3B3 ATAD3A NLN NOP2 PA2G4 KPNB1 MPI DNMT1 ILF2 CCNE1 CEP192 PDCD11 ADAM12 FOXRED1 YDJC DNAJA3 LMNB2 MNS1 DHODH EPHB2 DPH2 ENAH C1orf131 MYBBP1A CENPQ MFSD2A HDAC1 MLEC GEMIN5 ANP32E AGPAT5 DLK2 NOC2L PRMT7 ASNS NUP85 ATAD5 COX10 ENC1 ELAC2 CCT7 YARS2 GEMIN6 PTN PFAS PPP1R8 LRRC59 FAM136A RPA1 CDR2 MCM6 RPL7L1 PRMT1 UTP20 MCM5 NOC4L HEATR1 ACOT11 HAUS6 CLUH LTV1 SRSF1 URB1 DNAJC21 DUS4L RCC1 ATAD2 TSR1 TCERG1 GTPBP10 SUV39H2 ME1 RTEL1 PDF USP39 WDR4 PCSK5 ABHD10 WDR77 HK2 LPGAT1 RAD51 FARSB ZWILCH SCOC ZMYND19 TARBP1 PAXIP1 ACP1 FAM118B WDR76 PGAM1 RBM19 ZNF131 CIAPIN1 FAIM POLR1B POLR1A PFDN4 MTHFD1 TRUB1 APEX1 TBL3 PNN NCAPD3 RASGRP1 MRPL20 PWP1 NOMO1 E2F7 RRS1 NAT10 NUP93 CYP11A1 BRIX1 RANGRF C9orf40 PCGF6 CLNS1A CD38	up	**
GO_REGULATION_OF_CELL_CYCLE	0.0000642	0.0013306	0.5384341	0.2695857	1.375957	1008	HMGA2 CCNO PKHD1 MCIDAS TRIP13 DDX11 FOXM1 CEP72 SPICE1 BRINP1 KIF20A MDM1 CDC45 TICRR CHEK2 BUB1B NEK2 TRNP1 CCNB1 SOX2 CENPF TIMELESS PAGR1 STOX1 NDC80 TBRG4 BRCA1 TTK CDK4 SMPD3 RACGAP1 BRSK1 E2F8 GTSE1 DBF4B KIF14 L3MBTL1 ANLN CNTD2 ASPM NABP2 STIL CEP70 PLK1 AURKB PTTG1 ECT2 ESPL1 CDC6 SOX9 TPX2 E2F3 TFDP2 CCNB2 FIGNL1 RBBP8 PRKCA CDC25A MYBL2 PRC1 ORC1 CCNF DTL MAP2K6 ZFYVE19 ZWINT CDT1 CDK5RAP3 DCTN2 SPDL1 HAUS5 RANBP1 CEP250 CASP2 HMMR BTRC SMARCD3 DLG1 NLE1 KIF23 FOXA1 MKI67 CUL9 CUL7 TP53BP1 FBXO43 KNTC1 RHNO1 KIF3B BUB1 LGMN MSX2 TOP2A MAP10 GPER1 AURKA EME1 CBX3 ODF2 ATR SFI1 TPR MAD1L1 E2F2 MSX1 POC1A CLSPN CXCR5 IL12B RRM2 TTLL12 CDCA5 PRKDC FSD1 NSUN2 TOM1L1 KIF11 GPSM2 HORMAD1 CDC25C SOX4 TGM1 EGFR EME2 SLC9A3R1 TOPBP1 CHEK1 NEK11 MAD2L1 PSMD4 SOX11 MDM2 AKT2 MGA PKMYT1 BRIP1 FBXL8 BLM PML CNOT3 ERCC2 MNAT1 STXBP4 SKP2 PES1 PSRC1 PTPN3 INCENP KNSTRN CKS1B TTBK1 AFAP1L2 CDKN2C NUSAP1 CBX5 ANAPC5 ING4 CTDSP2 CDK1 CDK12 CEP97 CENPJ RFWD3 GMNN E2F1 PSMB5 CCNJL TMEM8B DNA2 ANAPC7 FEN1 EZH2 CNOT11 SPAG5 EGF TAF6 METTL3 RAB11FIP4 MTBP PRKAA2 PSMC4 MAD2L2 KLHL22 FGFR1OP STK11 IRF6 GIPC1 MYO19 ANKK1 CEP63 INTS7 CCNE1 CEP192 CDC23 CDK3 TUBG1 DLGAP5 NEK10 CNOT2 PSMA5 MTOR NINL TACC3 RAD9A PSME2 RAD51D MTA3 TRIM37 FBXO4 MYBBP1A GAS2 FZR1 PKP4 NUDT16 CGREF1 KIF20B LAMTOR2 LIN37 SMIM22 TRIM32 ASNS SGSM3 ANAPC1 SND1 CDK13 PSMD2 ATAD5 CABLES2 CDC7 ANKRD31 PROX1 SH2B1 CENPV CKAP5 L3MBTL2 PSMB3 CDC20 RPRD1B	up	**
FXR1_TARGET_GENES	0.0000507	0.0010964	0.5573322	0.2695723	1.375398	959	FOXM1 C1GALT1 FOXA3 HJURP DNAH2 LRIG3 SLC9A2 PAIP1 AVIL TSFM CREB3L4 MRPL46 GPR35 ANKZF1 GTSE1 IFT122 UBE2Z NOL12 PLK1 NUF2 EFNA4 CENPA GPI WDR70 CDC6 PRKCA SLC35E3 LSR PHLDB3 CCNF ALDOC PLS1 MIS18A ZNF3 DZANK1 KRT15 SLC4A8 AGK LSM5 KAZALD1 TAMM41 IKBKE AARS2 SIPA1L3 TOP3B TJP3 CASP2 NEURL2 ZNF607 CISD1 NOP9 BBS1 PAQR4 CUL9 FBXW9 ZNF587B SAE1 LARS2 MAD1L1 DPCD MDFI RBM28 ASPHD1 WDHD1 ANKDD1B MORN1 MRPL3 ENTPD6 SLC4A11 WDR73 XXYLT1 CAPN12 ASB16 CSRNP2 ABCB9 MRPS11 B4GALT7 PKMYT1 OGFOD2 SYMPK NOL3 FBXO16 ALDOA ZNF587 ERCC2 NRG4 PIGO SRRM5 PPP1R37 DHRS13 DDX56 GEMIN4 CASP6 MSTO2P C9orf163 PPIL2 FRMD5 ANAPC5 DMKN WDR5B DTD1 ATP2A1 PLCH1 XRRA1 PHF12 ANKRD54 POLR3K CTXN1 CMTR1 PGBD2 TMEM182 DPH7 TNPO2 SEMA3A SNRPE HMGXB3 NOP2 ZNF623 RECQL4 SUSD4 PA2G4 RNASEH2A LZTR1 UNC45A ZNF692 NRGN MPI ZNF606 SNRNP25 DENND6B SPEF1 CAPS2 ZGPAT ARFRP1 ADNP MORC2-AS1 DNAJA3 ADAT1 EFCAB2 MBD4 XYLT2 COG7 MRPL11 HIRA TIGD6 FBXO4 ZNF544 KCNC3 PLEKHA8 JMJD4 POMT2 GAS2 PCDH9 ACAD10 LIN37 DNAJC11 ZNF768 KRBA2 SGSM3 TSEN54 ELMO3 POLD1 NUP85 FAM200A ZNF814 PEX10 ZBTB45 MAMSTR NADSYN1 LSM14B SLX4IP EPN1 DHRS1 STRN4 TIMM13 IARS2 RIN1 CHCHD1 TTLL3 FAHD1 HMGB3P22 PPP6R1 CDR2 SRRT ABCA7 DNMT3A METTL2B MRPL28 WDR83 RAI14 ZSWIM8 TMEM147 KPTN LRRC73 SNAP47 LANCL2 MRPL53 PYGO2 SLC35A3 SCYL3 HAX1 C1orf109 CYP2D6 HMCES RCC1 IGHMBP2 SLC1A5 PSMB4 RAP2B LRRC46 CORO2A RRP36 DDX55 MVP ZSCAN16 ARFGAP1 LRRC14 SPAG4 SH3D21 RER1 CAPN15 TSPAN10 CYTH2 CCNA2 RBM42 DBNL GRHL1 ANAPC2 AMDHD2 PDAP1 ZNF462 WDR4 CLUAP1 INO80E HOOK2 TRAPPC9 SEC13 PPFIA3 TRIP6 GTF3C5 TYSND1 MRPL21 SNX19 CHMP2A FAM118B RHOT2 SNORA14B MXD3 OSGEP PNKP LIF SRCAP ZMAT2 ALG1 NMT1 KIAA1522 NEIL1 SEPHS1 APEX1 BPNT1 MRPS27 SNRPC UBE2C NSUN7 TAF4 PTOV1 FUT10 NELFA UBTF SART1 PIGQ TPRN ATF7IP MUC1 RNF32 THAP3 MRPS26 C4orf46 SH3GL1 TMEM201 PLXNB1 LINC00888 FTSJ3 SS18L1 C12orf10 CORO1B ANKRD13D ACIN1 MFSD3 CYHR1 PRKAR1B SUMF2 UNC119 EIF2D ZNF513 CHMP6 WDR55 PSTPIP1 INPPL1 RFFL SHQ1 PPP1R13L VPS16 SRM GSK3A DPY19L3 SIGIRR MFSD9 MRPL12 RPL36 SPRED3 HUWE1 TRABD ATRIP ZNF579 LAMA5 RALGPS2 SMYD3 MARVELD2 ZNF77 CHD8 HDDC3 RNF40 AMH ECE1 MLLT3	up	**
MIR20A_5P	0.0002154	0.0036503	0.5188481	-0.2265521	-1.374728	577	RAB11FIP1 EREG TMEM100 ABHD5 FGD5 SOWAHC ZC3H12C DPYSL2 ST6GALNAC3 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 C3orf70 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 CRK ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 MSR1 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 VASP ZADH2 STK17B FBXL3 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 CLIP4 PAFAH1B1 KPNA3 NCKAP5 TANC1 CNOT6L CNRIP1 VCPKMT ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PHLPP2 PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 UBE2D1 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	**
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	0.0000312	0.0007266	0.5573322	-0.2200197	-1.373038	705	SIDT2 SC5D CD52 FGD5 TMEM126A ZC3H12C CPEB2 WNT4 PTP4A2 RDX SMIM12 SEC22C PLEKHA1 INPP5A PRPF38A ARL8B CDC42 MKNK1 ANAPC15 CBL FRAT1 SYNC FGR CASP9 RHOA AVPI1 RBM7 PTS RRAGC MTF1 PICALM LUZP1 CAMTA1 GPBP1L1 ZBTB8A SLAIN2 FOXJ3 JAM3 MOB3C ZMYM6 TMEM123 EPM2AIP1 MTHFR ZYG11B ZMIZ1 EIF1B EFCAB14 AGO4 PER3 AMOTL1 ARRB1 PPT1 AGO3 CCDC82 SCP2 PSTK BIRC2 SORBS1 PTAFR FAM76A CLIC4 MYRIP SNIP1 ATG7 LAPTM5 LRRC40 CEP57 SS18L2 EPS15 CCSER2 WDR48 ZMPSTE24 LYAR PINK1 CUL5 OXSR1 PEF1 NRBF2 FAM76B AKIRIN1 IKZF5 CMTM6 CPLX1 PI4K2A RAB6A TBC1D5 RBPJ VAMP3 CHDH MED28 PODN PDCD6IP JUN MTMR14 LIMD1 GLUD1 OSBPL9 ATP6V0B BTD CNTN4 SHOC2 VPS26A JAK1 TBC1D12 DHX15 SDHD FRYL RPS6KA1 MSANTD2 CAP1 UVRAG SMIM20 MEAF6 CWF19L2 AZI2 MFSD10 RUNX3 ATPAF1 CHORDC1 PBRM1 SRSF4 ZRANB1 MTMR2 YTHDF2 KHDRBS1 TBRG1 DYNC1LI1 RELL1 HNRNPH3 APLP2 STK40 STX12 CLASP2 MACF1 CLCN6 TMA7 HAUS3 RPP30 MIER1 RLF ELOVL1 IQSEC1 RAB5A SIK3 TTLL7 NSUN4 HSPA8 TBC1D1 RBMS3 HPDL TBCEL NPAT FDX1 ANKRD49 PTEN THRAP3 KIF1B THEMIS2 C1orf52 SFPQ PUM1 FEZ1 GRPEL1 USP48 HPCAL4 MAN1C1 ACAT1 ZBTB44 MED17 PUS3 GPN2 VPS13D SPSB1 CDON USP4 PEX14 C1QB ARHGEF17 TMEM50A SH3BGRL3 FADS3 TMEM43 ZBTB8OS CAPZB CRBN CMPK1 GPR153 SH3GLB1 ECD HP1BP3 NAALAD2 PIGK SRSF11 MUL1 IFIT5 FAM160B1 NOL9 DNAJC8 LDB3 RGS12 C11orf54 EXOC6 ZNF362 BCL10 ACTR1A DDX21 RNF214 ARHGEF12 PNRC2 RPA2 KCNAB2 SH3BP2 SETD2 TAF1D BBIP1 FCHSD2 NKTR RAB11FIP2 CYTL1 MKRN2 SIRT1	down	***
GO_CELL_LEADING_EDGE	0.0011097	0.0137783	0.4550599	-0.2407996	-1.372598	345	AKAP5 ARHGAP31 SWAP70 DLC1 SCIMP FGD5 KCNA2 RDX CD44 CCDC88A INPP5K LDB2 CORO1C MYADM BAIAP2 PLEKHA1 CDC42 NEDD9 EPB41L3 FGR RHOA ATP2B1 PTPRM ADAM17 ITGA5 LCP1 NDEL1 SPTBN1 SPRY2 ARHGEF2 ATP6V1B2 AMOTL1 MTMR6 PTPRO MEFV ROCK1 PARVB VASP STX3 SSH1 VIM ARHGEF26 ARAP3 ACTR3 WASF3 PLEK ACTG2 UNC5A PAFAH1B1 RUFY3 ACTR2 KANK1 MYO1C FAM107A WASF2 APPL1 MTMR14 RAC2 DUOX1 MTMR9 APBB2 PALM FERMT2 SNX2 PODXL SNX1 GRIA1 DOCK8 SNX9 SPRY4 PKD2 PARD6A APBB1 GABARAPL1 CLASP2 MACF1 ARPC2 EPB41L5 RAB5A TIAM1 CXCR4 USH2A EPHA2 PARVA RAPGEF3 ABI3 ADORA2A PDE4A ARPC5 SAMSN1 IQGAP1 SHISA6 ATF4 SPATA13 PIEZO1	down	*
MIR3910	0.0004932	0.0072674	0.4772708	-0.2389202	-1.372430	352	RTKN2 SLC31A2 SEMA6A STAC LRRC8C MBOAT2 RCOR1 OTUD1 RGS9 QKI OTUD4 EDEM1 TRA2B TTL ZNF503 ANXA5 LCP1 PPP2R2A PPP3CA PTPN12 CWC22 EFCAB14 AGO4 ROCK2 AMOTL1 KLF4 SLC7A8 VASP TJP1 KLF7 SNIP1 RBMS1 UBE2B PIK3C2A ADIPOR2 MBD2 CUL5 SLC6A6 ZNF706 RBM44 FKBP15 AKIRIN1 TLL1 TAF13 RAB6A MYLIP MYO1C VAMP3 GZF1 CNTN3 CCDC50 RHOG APBB2 FERMT2 ENPP4 SP3 DDX5 PCGF5 SLC10A7 PDZD2 FAM177A1 ITGA11 ACSL1 CD164 PPTC7 EPHA3 PEA15 C16orf72 MAP3K2 CCDC68 ANKRD12 NPTN GNA13 RXRA PDLIM5 SLC31A1 SCN7A EPN2 DCTN4 CYP2U1 SSH2 ULK2 LYSMD3 KATNA1 RASSF8 FAM126B PRKG1 MMD ANXA11 NR3C2 MIER3 USP48 TRIM36 ARRDC2 KLC1 REEP1 SUGT1 CDON CFL2	down	**
GLI4_TARGET_GENES	0.0005595	0.0080583	0.4772708	0.2719181	1.372363	683	TF FOXM1 SLCO5A1 EYA1 RUVBL1 TICRR DNAH2 FBXW8 NUP107 DOC2A C17orf75 PSPH TSFM SLC25A21 NOL12 TTC26 IRX6 NUF2 WDR70 ZNF221 GRHL3 DTX3 CCT6A ZNF3 AGK NME1 TOP3B WDR62 TMEM41A ZNF391 C9orf116 SLFN5 AP4M1 RHNO1 CCDC77 GTPBP3 MCM7 SPEF2 RBM28 MRPL3 ANKRD13B CCDC58 PFN2 TARS2 FAM162A OAZ3 EME2 TRMT61B RAB13 RAD51AP1 THAP10 TMEM63A B4GALT7 GEMIN7 COMMD4 FLNB ALDOA TULP3 R3HDM2 OSBPL7 NRSN2 DDX51 ANAPC5 SLC39A11 CDK1 HDGF CDK12 SSBP1 ZSCAN25 STX18 TRIM2 DGAT2 MRPS2 DHX33 ENPP3 KLHDC9 KRBA1 TSPAN31 ZNF775 TMEM79 SMO NAPEPLD HMGXB3 ZNF827 VPS72 CENPP WDR24 ABHD4 ANXA2R KANSL1-AS1 PIAS3 GOLGA3 ZSCAN9 ACBD6 CAPS2 ILF2 SMG5 ARHGEF16 ZNF233 GALK2 ATP6V0E2 MTOR MRPS34 C19orf12 HIRA ARF5 DNM1 COPS7B FBXO4 CASP7 JMJD4 MLEC HECTD1 MTND5P11 STX18-AS1 GFM2 ZNF282 KDM3B FAM207A C12orf73 FAM200A PRRG2 MT-TH ZBTB45 NIF3L1 CCDC137 KDM3A BAZ2A EFCAB7 LSG1 PSMB3 VPS25 STOML2 AHCYL1 ZNF616 DUS1L FAHD1 PPP6R1 FANCM PEX5 CACNG8 WDR83 NOSIP NOC4L NMNAT1 ANKS3 SNAP47 LANCL2 NDUFS7 POLR3E IGHMBP2 DDX55 MST1P2 ZNF580 NME1-NME2 PRPF18 TSPAN10 BANF1 POLR3B CCDC167 STAT6 CDK5RAP1 PRPF31 BMS1 TRIP4 SEC13 MARK4 ECHS1 GTF3C5 SUPT3H SAMD4B MRPL9 SRP9 MRPL21 LINC00240 RHOT2 AGBL5 TMEM101 AURKAIP1 LZTS3 SNUPN CASC2 LRP5L ZNF131 TCF3 ZNF205 TRUB1 MCF2L2 PIGL DCDC1 FUT10 MRPL48 ZER1 MOK ANKRD13D SLC33A1 KIAA0586 EIF2D FGFBP3 SETD1A ANO8 MED22 MUS81 MAN2C1 C12orf43 PARL RPL36 NOXA1 SFT2D2 ZC3HC1 RBL1 ZNF771 CYB5RL RDH14 TNPO3 OPA1 ZNF579 NSL1 EDC4 MCEE TLE2 SLC4A1AP COQ5 TSC22D4 TLCD1 TEFM MTR IGDCC4 IMP3 MBD6 TIPIN MTF2 TIMM9 PSMD3 STEAP2 RPL41 BNIP1 DHPS DDX49 SLC44A1 PRKAB2 CACNA1A IPO4 METTL9 ZNF302 ACOT7 HNRNPA1 MPLKIP NUDT19 KLHL20 CLTC DNAJC2 SLC39A3 TSEN15 DHX30 CLPB RFC3 AJUBA NVL MPP2 JRK IFT74 BCKDHA REXO4 COX16 CIZ1 ATXN2L CUEDC2 KANSL1 DDX19A	up	**
MODULE_60	0.0011863	0.0145158	0.4550599	-0.2413617	-1.372073	336	EPAS1 CD52 SCN4A HMOX1 CLEC3B RAMP2 CDH5 ENG LPL CITED2 ALAS1 TGFBR2 TRIB1 HSPG2 CD8A FGR PDE2A APOD MAN2B1 HBEGF ACOT2 RNASE1 LAIR1 NR4A1 GNG7 GRN CES1 APOC1 MTHFR CD37 RHOB MAP2K3 CFD TNNC1 EPOR GPA33 GAA TJP1 CLDN5 GMPR CDKN1A KCNMB1 PNRC1 IGFBP2 CCND2 M6PR PRF1 FCER1G PER1 TBX5 WFS1 VAMP5 MYH11 PTGIS MAPRE2 VWF EMP3 KCNA5 CD8B FAM107A S1PR4 AQP3 LAMB2 CYB5R1 FAM189A2 RAC2 CYP2A6 ST6GALNAC4 PLK3 PPP1R15A CRYM MFAP4 FSTL3 CLN3 CST7 CD34 CD151 GJA4 NKG7 TGFB1 PARD6A FPR2 LRRC32 COL15A1 CCR1 FCGRT PLEKHO2 SOD3 GPX3 PDLIM5 HTR6 SPIB TOB2 BCAM IFFO1 RBMS3 S100A4 ICAM3	down	*
GO_MUSCLE_CELL_DIFFERENTIATION	0.0008872	0.0116078	0.4772708	-0.2486670	-1.371561	288	EREG FOXF1 EDNRB TBX3 WNT4 RAMP2 BMP2 SIK1 ENG BDNF TMOD3 QKI FGF10 PRKAR1A MEF2A CDC42 CD9 NFATC3 TBX2 MYOZ1 CACNA2D2 LMNA CSRP1 TMEM204 CAV2 PPP3CA RBM4 RB1 WNT3A ZEB1 HNRNPU TCAP SETD3 NPNT BNIP2 CDK9 SPAG9 MIR24-2 CD53 ZMPSTE24 TBX5 CYP26B1 MYH11 HES1 TANC1 LMOD3 PIAS1 MTPN SRF RBPJ SLC8A1 TMOD1 YBX1 MED28 NOTCH1 ADRA1A EPC1 IFRD1 HOMER1 CACYBP EHD2 FLNC SYPL2 SORT1 TGFB1 EHD1 MIR23A CD81 SOD2 MYOCD GATA6 ACTN2 RGS2 RXRA PDLIM5 WDR1 LMOD1 ARRB2 TMOD2 KIT EDN1 SKI SYNPO2L RORA NRG1	down	*
MIR181D_5P	0.0003159	0.0050903	0.4984931	-0.2306639	-1.371054	502	TRIM71 IL1A ATXN3 ADCY9 MBOAT2 RAB3C SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 OTUD4 ZBTB2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 ADARB1 AGO4 PER3 ADO SLC38A11 NR1D2 TADA2B RECK ZBTB43 UBE2B ELMSAN1 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF CDC40 PHTF2 NEK7 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 IRS2 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL PKNOX2 LIMCH1 RASSF8 FNIP2 CECR2 FAM126B KIF1B RORA DOCK4 GRB10 MIER3 DMXL2 CBX7 KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1	down	**
MIR656_3P	0.0010113	0.0128345	0.4550599	-0.2405526	-1.370473	342	EREG EDNRB USP12 ZC3H12C PTP4A2 PTPRE ST6GALNAC3 KL BDNF FYN CD44 CCDC88A BACH1 RASAL2 CALCRL VAMP2 KCNN3 MOB1B PTPRM SBDS RAP1A CAV2 NR4A1 RGCC TNS1 TMEM41B ZEB1 FBXO8 MSR1 RAB12 SGTB KLF4 ZFAND5 CEBPA MYO1B GAPVD1 NPR3 GMPR SSH1 CCND2 UBE2B DUSP1 BRF2 TBX5 PPP2R5A CYP26B1 NCKAP5 CDKN2AIP TDRD7 FOXN3 SACM1L SPIN1 CREBRF FRY ELF1 KIF13A NEK7 INPP5B NXF1 TMTC1 CPEB4 BMP3 CNTN4 JUNB SKIL EEA1 SP3 FRYL IDS CREB1 COBLL1 CXCL5 UVRAG OCIAD1 KLF2 YPEL2 ZNF175 FAM204A DDHD2 STRN NDUFA5 SERPINB1 TEC SBF2 GOLGA8H KYNU RIMKLB KAT2B SMAD2 ABL2 SFT2D1 LMOD1 SEC63 USPL1 SIK3 PTCH1 ZDHHC21 TMEM184B SSH2 TIMP3 DOCK10 PRKG1 MMD C21orf91 RORA FAM13B NAA15 EIF4A2	down	*
E2F5_TARGET_GENES	0.0000905	0.0017795	0.5384341	0.2686417	1.369998	968	PCSK6 TRIP13 FOXM1 FOXA3 CPLX2 CEP89 PARPBP FANCI GPT2 LYSMD1 TFAP2A RPGRIP1L CHEK2 CP BUB1B ZNF84 CENPF UBE2T PTPRN2 GBAP1 PBK KIF18B CHCHD6 NDC80 DEPDC1 DEPDC1B CDCA7 CDCA2 EFNA3 SMPD3 RACGAP1 IQGAP3 ANKZF1 CABIN1 POLE STIL DGCR8 PLK1 NUF2 CDCA8 AURKB CENPA ACAD9 ESPL1 TPX2 E2F3 CCNB2 STC2 MCM4 PRKCA MCM2 CA12 ZFYVE19 VILL RCCD1 ZWINT SMUG1 INTS1 RANBP1 TTLL4 OSBP2 MELK BTRC PODXL2 MKI67 BOD1 QTRT1 STAP2 KIF15 TRIM29 AP4M1 RHNO1 WASF1 TOP2A FBF1 ANO7 EME1 P4HTM SEZ6 SMARCAL1 MCM7 MAD1L1 E2F2 CENPW RRM2 CDCA5 PRKDC RHOBTB3 SGPL1 SDK1 RAD54L SBK1 MRPL27 ANKMY1 FANCD2 MCM3 LMNB1 CDC25C SEC61A1 ZNF785 YEATS2 BRD9 CHEK1 ZYG11A PEX26 THYN1 ORC6 HSF2BP SCAMP5 SRD5A3-AS1 CENPO MDM2 TRMT2A AKT2 LRRC61 BLM PHB ZNF605 CCDC136 SYMPK ALDOA TULP3 CNPY2 KNSTRN ZNF32 TTBK1 ZNF45 PPM1E CDK12 STON2 POLE2 EXOSC2 BIRC5 NUDT2 XRRA1 PHF12 SRCIN1 E2F1 UNG PSMB5 NEIL3 KCNK12 METTL3 SLC12A8 UCKL1 DIAPH3 CPXM1 ACVR1B DENND1A RANGAP1 CHCHD2 MPI ZNF687 ZNF354A DNAJC17 AKR1E2 CCZ1B VIPAS39 DLGAP5 C19orf44 DCAKD NADK2 MRGBP NFASC UBAC1 TSNAXIP1 ADNP ZNF133 LMNB2 XYLT2 CCDC151 KIF22 MRPL52 COX7C ZNF37A FBXO15 COPS7B UBE2Q1 TK1 KCNC3 ZNF239 ARHGAP5-AS1 CCDC146 GINS2 ANP32E TSSK3 KIF20B LAMTOR2 TM9SF4 SAP30 SLC4A2 FHL2 ACSL6 MAGOHB CEP128 CCDC159 ATAD5 AAMP ATP13A1 TCEA2 SLX4IP SASS6 UBQLN4 CENPV ACBD5 NFXL1 TSTA3 CKAP5 UBE2O KCNB1 NPRL3 DUS1L MADCAM1 CDK5RAP2 CLINT1 MCM6 MGME1 EML6 PPCDC CENPT NOSIP MCM5 GNG4 DDX23 NSD1 RTEL1-TNFRSF6B SRSF1 C1orf109 NFE2 STMN3 DOLPP1 SUGP1 SH3BP5L ATAD2 PATZ1 FARSA AP2S1 ADORA3 TSC2 CCNA2 SMARCA4 RCN3 GRHL1 RTEL1 CANT1 PLSCR2 MRPS25 SHCBP1 SCNM1 LINC00964 DTNB GTPBP2 ZNF436 USP39 ACSF3 CCDC88B MLLT6 RAD51 STK25 TOMM40L FBXW11 ARHGAP5 ST20	up	**
HOXB6_TARGET_GENES	0.0018986	0.0205607	0.4550599	0.2758922	1.369988	520	ATP10B FOXA3 RPGRIP1L CCDC34 TIMELESS SEMA4B NDC80 C12orf66 CDK4 IFT122 HILPDA NABP2 PCLO AP1S1 TOMM34 CEP70 EFNA4 GPI GAPDH RBBP8 HOXB7 SLC35E3 PRC1 XRCC2 KAZALD1 FAM220A NME1 HAUS5 WDR62 RSPH1 TTLL4 ZNF862 NLE1 SYTL2 SPAG16 TP53BP1 PCCB TSGA10 TIGD4 LGMN TOP2A EME1 C1orf226 SAE1 CENPW CDNF SETDB1 CCDC114 NME9 MRPL27 WDR73 B3GNTL1 WDR60 IFT172 TRMT61B MDM2 TBC1D8 PPP5C SYMPK C4orf47 SRRM5 TULP3 POLN C12orf75 RNPC3 GMNN SMG9 STAT2 MKRN1 ZNF584 ANKRD26 CNOT11 THAP8 GOLGA5 LRRC56 CHCHD3 ELMOD3 ZSCAN21 EDEM3 RHOC TUBG1 C19orf47 ENTPD3-AS1 GSS DNAJA3 NMRAL1 MAN1B1 MBD4 CCDC151 ZMAT5 TRIM37 COX7C FBXO15 CSNK1G1 HIP1R FZR1 PDRG1 MAPK10 XPR1 SLC4A2 DNMBP C15orf41 CDK13 MAGOHB ZBTB45 CNDP2 P4HA1 UBE2O ERBB3 CCDC30 EFHC1 HMGB3P22 FITM2 SRRT ABCA7 RPPH1 WDR35 ZRANB3 UIMC1 SRSF1 HOXA-AS3 AATF EXOSC5 LSM4 EIF3K U2AF2 CEP152 MST1P2 PRMT5 GADD45G NME1-NME2 B9D1 MAP3K14 ULK4 ZNF195 MRPL55 ABCF2 PCSK5 UQCRC1 N6AMT1 TPGS2 PPFIA3 KIAA0825 CHMP2A ACP1 CDK5	up	*
MIR4699_3P	0.0005739	0.0082422	0.4772708	-0.2354898	-1.368933	404	SLC31A2 SASH1 DLC1 USP12 GREB1 KCNA2 ZC3H12C PTPRB ZBTB34 TMEM170B SH2D3C TXNL1 CALCRL PLEKHA1 ARL8B MEF2A KBTBD3 FBXO3 PPM1D KCNAB1 UBR3 PTPRM TTL RAPGEF4 ASAH1 PLXNA2 C1orf21 NLK PAQR3 HLX DACH1 FOXJ3 ADRB2 TMEM41B TFEC RAB14 GPR4 RAB12 PIP5K1B PXDC1 PRKD3 ZFAND5 NFKB1 PNRC1 ARL4A N4BP2L1 GNAQ TM9SF2 PDE1C CNOT6L TGFB2 STK24 SACM1L RBM39 SLC8A1 FMNL2 ELF1 BCAR3 GABARAPL2 HSD17B13 PIKFYVE C20orf194 ADRA1A BMP3 APBB2 TBC1D12 DHX15 SKIL EEA1 LSM1 TUBGCP3 CGGBP1 ZNF407 OCIAD1 PELI1 PTP4A1 ING3 AZIN1 DDHD2 VAV3 STRN PHF3 ABHD13 RSBN1L MPV17L CNOT7 MAP3K2 STX12 CRY1 ARPP19 INO80D SLC35D2 INTS6 PDLIM5 VGF ARHGAP18 USH2A MEX3C NPAT KIT SCAI FAM126B KIF1B SAMSN1 RORA NRG1 RHOT1 C1orf52 FCRL1 RABGEF1 DMXL2 STARD13 DUSP6 EXPH5 MAMDC2 CMPK1 SLC38A2 NOG TBC1D23 KCNJ1 CSNK1G3 ADAMTSL3 PIK3CG IFIT5 SGIP1 UNC50 MTSS1 ANGPT2 SGPP1 TMEM220 POLR2B MAP3K1 FASTKD5 CCPG1 NKTR RAB11FIP2 CLVS1 MPDZ ARGLU1 MSC SKP1 LARP7 IREB2 EMP1 CBFB ZCCHC14	down	**
MIR3973	0.0028230	0.0277568	0.4317077	-0.2505813	-1.368427	219	PTPRE ARRDC4 ZCCHC2 PLEKHA1 RGPD5 PDCL HBEGF RNF144B CSGALNACT2 HIPK3 TCF7L2 GPM6A FBXL5 CWC22 MTMR6 BNIP2 ATP6V0D2 UXS1 ACTR3 SMAD7 ZNF706 NUS1 AKIRIN1 IKZF5 CREBRF PRKRA RNF149 ADCY2 RAB8B PIKFYVE PSMA1 GABPA ZFP91 APBB2 VPS26A WTAP BAG5 IFRD1 FSD1L GTDC1 OGFRL1 BLOC1S6 CDK17 HIVEP2 MAPK8 TSHZ3 NAA16 AZIN1 VAV3 DCK CCP110 BAZ2B VAMP4 SBF2	down	*
MIR181C_5P	0.0002540	0.0042184	0.4984931	-0.2300582	-1.368286	504	TRIM71 IL1A ATXN3 ADCY9 MBOAT2 RAB3C SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 OTUD4 ZBTB2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 ADARB1 AGO4 PER3 ADO SLC38A11 NR1D2 TADA2B RECK ZBTB43 UBE2B ELMSAN1 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF CDC40 PHTF2 NEK7 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 IRS2 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL PKNOX2 LIMCH1 RASSF8 FNIP2 CECR2 FAM126B KIF1B RORA DOCK4 GRB10 MIER3 DMXL2 CBX7 KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1	down	**
GO_MUSCLE_SYSTEM_PROCESS	0.0006712	0.0093526	0.4772708	-0.2403501	-1.367521	341	SCN4A HMOX1 STAC EDNRB IL1B P2RY1 TRPC3 TMOD3 CAV1 NEDD4L CALCRL ADRA1D TBXA2R MEF2A SCN5A RHOA MYOZ1 ATP2B1 ADA LMNA CHRNE NMUR1 DES PPP3CA ADRB2 TCAP PDE4D SGCA SETD3 TMEM38B CNN1 SORBS3 MAP2K3 ROCK2 TNNC1 FOXO1 KCNMA1 SORBS1 NPNT TACR2 PTAFR KLF4 ROCK1 GAA CDK9 VIM MIR24-2 PTGER3 PIK3C2A SMAD7 RAP1GDS1 ACTG2 MYH11 CALM2 MIR17HG LMOD3 MTPN SRF KCNA5 SLC8A1 SCN4B TMOD1 UTRN NOTCH1 ADRA1A PDE5A GSTO1 PRKACA HOMER1 LMCD1 CALM1 FOXO3 MYL12A MIR23A KCNN2 SLC8A3 GLRA1 MYOCD GATA6 ACTN2 RGS2 PDE4B PDLIM5 SCN7A LMOD1 TIAM1 CXCR4 TMOD2 GPD1L KIT EDN1 PRKG1 P2RX1 DOCK4 SMAD4 EHD3 SPHK1 CYBA KLF15 KCNE1 FKBP1B GJC1	down	**
MIR181A_5P_MIR181B_5P	0.0003109	0.0050325	0.4984931	-0.2301248	-1.366594	503	TRIM71 IL1A ATXN3 ADCY9 MBOAT2 RAB3C SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 OTUD4 ZBTB2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 ADARB1 AGO4 PER3 ADO SLC38A11 NR1D2 TADA2B RECK ZBTB43 UBE2B ELMSAN1 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF CDC40 PHTF2 NEK7 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 IRS2 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL PKNOX2 LIMCH1 RASSF8 FNIP2 CECR2 FAM126B KIF1B RORA DOCK4 GRB10 MIER3 DMXL2 CBX7 KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1	down	**
GO_REGULATION_OF_SUPRAMOLECULAR_FIBER_ORGANIZATION	0.0008944	0.0116503	0.4772708	-0.2467402	-1.366554	280	SWAP70 DLC1 WNT4 RDX GPR65 CDH5 ARHGEF15 SHANK3 TMOD3 INPP5K BAG4 KANK3 MYADM BAIAP2 CDC42EP2 ESAM S1PR1 DYRK1A CDC42 CIT RHOA SPIRE1 SLAIN2 RB1 RGCC SFRP1 SPTBN1 ARHGEF2 SORBS3 ROCK2 SYNPO ROCK1 VASP COTL1 C9orf72 ACTR3 CAPZA2 PLEK DSTN ADD1 ACTR2 LMOD3 HCK MTPN NCKAP1L KANK1 MYO1C TMOD1 WASF2 SYNPO2 PSEN1 HSPA1B ARHGEF10 PTGER4 CCR7 PIK3R1 GMFG PRKCE GRB2 PPM1F SNX9 WNT11 TTBK2 WHAMMP3 CLASP2 ACTN2 ICAM1 ARPC2 WDR1 LMOD1 CDC42EP3 TMOD2 ARHGAP18 HSPA8 LIMCH1 RAPGEF3 EDN1 ARPC5 SYNPO2L CAMSAP2 LDLR	down	*
CTTTGCA_MIR527	0.0054277	0.0453599	0.4070179	-0.2531441	-1.366449	201	USP12 CORO1C SRSF7 PAFAH1B2 MKNK1 GNPTAB OTUD4 ZEB2 SEMA6D ZBTB4 PTPRM TACC1 RAP1A PLXNA2 C1orf21 RAB33B FZD4 RHOB TAPT1 CCDC82 KCNMA1 GPR85 ACTR3 KPNA3 AKIRIN1 MYLIP SOCS3 RAB8B HMBOX1 CPEB4 ATP11A FYTTD1 DAPK2 MBNL2 NAA30 MORF4L1 RUNX3 PBRM1 AP1G1 CNOT7 ATXN1 HBP1 ANKRD12 MBNL1 ARPP19 ARPC2 KPNA4 ULK2 MAFK RNF38 FOXJ2 PTEN KIF1B NR3C2 FAM13B ZFPM2 PUM1 MIER3 DNAJA2 CBX7 CHIC2 ZNF800 NR4A2 EFNB2 API5 WDR47 PDE7B FNDC3A MEF2D RNF111 WDR26 FCHSD2 SREK1IP1	down	*
ADA2_TARGET_GENES	0.0006402	0.0090149	0.4772708	0.2694129	1.365211	756	HMGA2 MNX1 CPLX2 RUVBL1 FBXW8 PDCD6 NUP107 C17orf75 ZFHX4 DDIT4 NUDCD3 THEM4 ECE2 ZFP62 NOL12 TENM2 EIF2B5 TTC26 NUF2 E2F3 MCM4 TIGD1 NCAPD2 COQ3 CDK5RAP3 SPDL1 AGK UQCC1 LSM5 FAM220A NME1 TOP3B TMEM41A ZNF391 CHAF1A BBS1 ZNF850 AP4M1 RFXANK PMS2P4 ATR GTPBP3 TMEM132A MCM7 RBM28 MRPL3 SLC4A11 SBK1 EMG1 TARS2 YEATS2 RNFT2 EME2 BMS1P1 GET4 ABCB9 THAP10 B4GALT7 GEMIN7 EEFSEC SPAG8 OGFOD2 INPP4B MTG1 ALG3 MNAT1 KNSTRN ANAPC5 CTDSP2 SSBP1 DTD1 TESC ADAP1 STX18 MAP3K10 MCAT MKRN1 WDR31 AP5Z1 DHX33 ENPP3 KLHDC9 DPH7 ANAPC7 POLR1C PSMG3 TTC23L POC1B SF3B3 TNRC18 SEMA3A MTBP HMGXB3 NOP2 CCDC57 ZNF827 MAD2L2 ZNF623 CENPP WDR24 YEATS2-AS1 DNAJC7 CHCHD2 GOLGA3 ZSCAN9 ACBD6 SLC35C2 NDUFA11 GALK2 TRMU MTOR TACC3 MRPS34 YIPF3 PLEKHG3 KIF22 HIRA TIGD6 COPS7B ARL6IP4 DBN1 JMJD4 MLEC STX18-AS1 ZNF768 GFM2 COG4 TSEN54 FAM207A C12orf73 PRRG2 CCDC159 ZBTB45 CABLES2 NIF3L1 BAZ2A PPIEL PROX1 SH2B1 EFCAB7 MDGA1 LSG1 VPS25 STOML2 DUS1L FBXO22 NAT8L FANCM CACNG8 WDR83 CELF4 NOSIP NMNAT1 TDP1 SNRPD1 SNAP47 EIF3D SLC35A3 STMN3 NDUFS7 MRPL51 YIPF2 IGHMBP2 DDX55 ZNF580 NME1-NME2 PRPF18 BCL9 TSPAN10 ZNF195 BANF1 RTEL1 POLR3B AMDHD2 TUBGCP4 CDK5RAP1 ZNF462 ACSF3 BMS1 ZNF384 TRIP4 SEC13 RNF123 PFKM GRAMD1B MARK4 GTF3C5 ZSCAN22 MRPL21 KIAA0825 AIFM2 VPS9D1 TMEM101 AURKAIP1 OSGEP POLR1B BCL6 ZSCAN29 EIF4G1 NDOR1 ZNF205 APEX1 PIGL DCDC1 BCAT2 NELFA PIGQ ZSCAN20 MRPL48 ZER1 TRUB2 HEMK1 SLC33A1 KIAA0586 INO80B EIF2D NUMBL FGFBP3 KLK10 MED22 MAN2C1 SPHK2 VPS16 GSK3A C4orf48 FAM120A DPY19L3 NELFB EIF2B1 MST1 RPL36 NOXA1 LOXL1-AS1 ZC3HC1 SPRED3 ZNF276 APBA3 TNPO3 TRABD OPA1 ZNF579 NSL1 EDC4 MECOM MCEE SLC4A1AP STARD10 TSC22D4 MTMR4 TEFM ZNF682 PGAM5 SLC20A2 MTR DLGAP4 C1orf194	up	**
GO_REGULATION_OF_VESICLE_MEDIATED_TRANSPORT	0.0003720	0.0058397	0.4984931	-0.2323803	-1.365068	438	SIRPB1 CD300LF FOXF1 HMOX1 PPARG GATA2 SFRP4 IL1B P2RY1 RDX RAB3C INSIG1 PCSK9 STXBP6 CAV1 NEDD4L PRAM1 CDH13 VAMP2 MIR27B GAS6 LAMP1 CBL CD22 SLC11A1 FGR NUMB CD36 ANXA1 CNST MCTP1 RAPGEF4 RAP1A CLEC7A RAB33B PICALM PTX3 PPP3CA SIRPA WNT3A ZFYVE16 MAPK8IP1 APOC1 PPP3CC ARRB1 RAB12 PPT1 SDCBP ACSL3 PTAFR REST ROCK1 DAB2 SEC24B PTPRC AXL ARC SFTPD FCER1G RNF139 LYAR GNAI2 TBC1D4 C4BPB BACE1 CPLX1 HCK NCKAP1L TBC1D5 SNX3 SAR1A LRRTM2 IL2RB APPL1 MAGI2 RAB8B PDCD6IP NOTCH1 RAB31 ADRA1A RAC2 RAPGEF1 GRASP RAB8A UNC13B RALB PLCG2 CD151 EHD2 ATG3 PRKCG EPHA3 STXBP3 EHD1 AP1G1 VAMP4 FPR2 MTMR2 PCDH17 LGALS3 ANKRD13A STON1 CLASP2 ACTN2 PLAA SYT11 UNC13D BMP2K ABL2 CHMP3 ARRB2 RAB5A VPS4B	down	**
HAN_SATB1_TARGETS_UP	0.0011085	0.0137750	0.4550599	-0.2350352	-1.365066	371	KRT81 RAB11FIP1 EPAS1 SLPI IL1B PTPRE LIPA ENG BDNF FYN STXBP6 SAMHD1 ST3GAL6 CITED2 QKI CYB5R3 HMGCR ARL8B SLC15A3 NEDD9 RGPD5 EPB41L3 SLC25A17 ECHDC1 FZD4 SLC7A11 IL18R1 TNS1 SPTBN1 SRGN EPM2AIP1 PDE4D TCF7L2 APOC1 RHOB ADARB1 EVI2B CASP1 ZCCHC24 TNFSF15 BCHE GRK5 KLF7 ATG7 PDE8A PMM1 CDS2 M6PR WASF3 DUSP1 INHBA MATN2 IL7R CYP26B1 MAFF TGFB2 RPS6KA2 MCMBP PDHX FLT1 IL6 RAB8B LAMB2 SERPINB8 MITF HRH1 CTSZ BMP3 OSTM1 SHOC2 CSTA ZNF804A ATP13A3 DENND4A NDUFV2 MCAM CD34 CD164 MBP RBKS MSMO1	down	*
MIR10399_5P	0.0015534	0.0176983	0.4550599	-0.2389898	-1.364911	316	ZC3H12C CPEB2 SNX10 EMP2 ST6GALNAC3 PTPRB RASAL2 MS4A15 QKI BMPR2 TGFBR3 MOB1B RCHY1 CNST TRA2B RAB33B BZW1 NLK PRSS12 EIF4E LHX6 MPHOSPH6 SPTBN1 MAPK8IP1 PDE4D ROCK2 TLE4 FOXO1 PPP6R3 KLF4 ITM2B PEG3 PLEKHM3 ANKRD10 GAPVD1 CYP20A1 RECK UBE2B CAPZA2 CCSER2 PRICKLE2 IKZF5 SIAH1 TGFB2 METAP1 YBX1 SGK1 KIF13A PHACTR2 NEK7 INPP5B SH3BP5 CNTN4 EEA1 HSPA13 CREB1 CTTNBP2 NECAB1 HIVEP2 MAPK8 NAA16 DCK PDS5B RSBN1L TMEM230 MYOCD RIMKLB KAT2B ABI3BP ATAD2B INO80D RNF138 ABL2 CTTNBP2NL SFT2D1 NT5C2 RAB5A TMOD2 ARIH1 PTCH1 PSME4 SRSF10 RASSF8 DOCK10 SCAI FAM126B CAMSAP2 CCND3 SHISA6 SPATA13 EIF4G2 ABI1 REEP1 PLAG1 PEX14 TBPL1 GJC1 NR4A2 MAPK1 CTDSPL2 SV2B SPTY2D1 SGIP1 HMGB1 CUL2 CRIPT FAM218A PNRC2 SLC23A2	down	*
GO_STRUCTURAL_MOLECULE_ACTIVITY	0.0024391	0.0249191	0.4317077	0.2757894	1.364622	491	COL17A1 TFPI2 FGA MYBPH KRT5 COL24A1 LAD1 NUP107 CENPF MUC4 PKP1 COL27A1 ZP3 MRPL46 TUBB2B MUC5AC COLQ COL28A1 ENAM PCLO COL7A1 YEATS4 KRT16 COL22A1 PLS1 COPB2 VILL MRPS35 MYL6B KRT15 TNC CLDN1 MUC6 DLG1 MAP7 LAMC2 RPL39L BICD1 MRPL15 COPG2 COPG1 MYBPC2 SPTB NUP155 ODF2 TPR FLG FGG CD2AP MRPL3 MRPL27 LMNB1 NEB MRPS11 MRPS30 KLHL3 CLDN9 MYOT MRPL36 LAMB4 CLDN15 MRPL37 KRT18 CROCC ERC2 MRPS2 MRPL17 COL3A1 NUP205 MRPS12 IMPG2 NPHP1 COL1A1 TUBG1 COL1A2 COL9A2 MRPS34 TUBB2A TUBA3D MRPL11 COL5A2 MRPL52 TUBA8 PRG4 SPTBN2 MRPL4 CLTA DAP3 KRT19 CHADL EPB41L4B NUP85 CLTB COL11A1 VPS25 TUBG2 HMGA1 MRPS23 MRPL24 UPK1B MRPS33 COMP MRPL28 MRPL41 RPL7L1 COL5A3 BSN ADD3 CLDN16 MRPL51 ANK3 NEFH NUP62 SPAG4 MRPL14 RPS26 MRPS25 MRPL55 TUBGCP4 TUBA4B ANK2 SEC13 FBN2 COPA FMOD MRPL9 MRPL21 LLGL1 CPOX VWA1	up	*
MIR548F_3P	0.0005500	0.0079478	0.4772708	-0.2334259	-1.364238	416	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP TMED5 MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 PIKFYVE RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	**
GO_SUPRAMOLECULAR_POLYMER	0.0005947	0.0084838	0.4772708	0.2699787	1.364086	694	KIF1A SAA1 KIF12 KLC3 KIF20A MYBPH MDM1 KRT5 PKP2 DNAH2 RPGRIP1L NEK2 TNNI1 KIF18B PKP1 COL27A1 SLC2A1 TUBB2B RACGAP1 GTSE1 KIF14 SPAG17 ASPM PLK1 KRT16 AURKB TPX2 CMYA5 DNAH3 PRC1 PLS1 DYNC1I1 CCT6A KIF27 MYL6B CDK5RAP3 KRT15 DNAH14 CCT2 DCTN2 NME1 MICALL2 DNAI1 HAUS5 RSPH1 TTLL4 TNNT2 NOS1AP DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 KNTC1 KIF3B FBF1 IDO1 MAP10 MYBPC2 CCT5 GPER1 AURKA ODF2 FLG KIF2C CD2AP MAP1LC3C TEKT2 FSD1 HOOK1 DCDC2 FHOD3 KIF11 LMNB1 DNAH8 NEB GAS8 KIF3C DNAH11 FLNB ALDOA TRPV4 MYO1A PSRC1 INCENP KNSTRN MYOT NUSAP1 PAK1 KRT18 CDK1 DNAH6 KIF5A CENPJ BIRC5 CCT3 TTLL9 JAKMIP1 SCTR TNNI2 KIF19 SPAG6 KIF2A NARF KIF7 COL3A1 DYNLL2 SPAG5 DNAH5 KLHL22 EIF6 UPP2 COL1A1 TUBG1 COL1A2 DNAH7 DNAJA3 NINL LMNB2 MNS1 TUBB2A TUBA3D KIF22 KY COL5A2 DNM1 DBN1 TUBA8 SCN8A KIF21A GAS2 HID1 MAP6D1 KIF20B TRIM32 SMTNL1 KRT19 FHL2 AHNAK2 TWF1 POLB CCT7 COL11A1 KLC2 KLC4 CKAP5 ABCC9 TUBG2 TTLL3 FBXO22 CDK5RAP2 KRT8 DYNC1LI2 KIF21B EML6 TBCA CKAP2 COL5A3 DNAI2 KPTN ANKRD1 HAUS6 DYNC2H1 FAM161A RAB3D KATNB1 SKAP1 MYH7B TTLL6 HAUS4 MYH3 ANK3 NEFH TCHP KRTAP5-9 MYH13 MICAL3 APC2 SCO2 DBNL NAV1 TUBGCP4 SYBU ACKR2 CCDC181 DNAH1 HOOK2 TUBA4B ANK2 TPGS2 NBR1 NOS1 FBN2 CDK5 CTTN TBCB BCAS3 CAMSAP3 CENPE MAP1LC3A SRPRB GOLGA2 ESPN SYNE2 TTC30B DCDC1 PNN KRT80 ENO1 TUBA1C KRT17 MAP9 BFSP2 DNM1L TTLL5 CLASP1 KIF24	up	**
GO_PROTEIN_HETERODIMERIZATION_ACTIVITY	0.0032442	0.0310004	0.4317077	-0.2392496	-1.362504	307	PRMT8 RBP4 EPAS1 TAL1 PPARG SLC51B P2RY1 BMP2 CAV1 PAFAH1B2 MEF2A BCL2A1 VAPA CLCF1 FBXO7 RRAGC SLC3A1 FZD4 ABCG1 CAV2 ADIPOR1 ADRB1 PPP3CA NR4A1 JAM3 MCL1 PDGFA SDCBP AOC3 ARNTL MAFG NFKB1 NPAS3 ITGAX ATF3 IRAK2 AXL JAM2 TLR4 TAF9 GCA INHBA ADIPOR2 PEF1 ADD1 ANO2 TAF13 TGFB2 HEXB SRGAP2C TFAP2E PPP2CA ADCY2 PKNOX1 TAS1R1 JUN GABPA ADRA1A SNX2 PIK3R1 MAPK4 SNX1	down	*
GO_RESPONSE_TO_NITROGEN_COMPOUND	0.0000058	0.0001772	0.6105269	-0.2174413	-1.362188	875	SLC6A4 GPD1 EREG RAMP3 LPIN2 TEK EDNRB PPARG ADTRP GPIHBP1 HHEX CPEB2 IL1B ATXN3 LHCGR CAT ADCY9 P2RY1 ADCY4 RAPGEF2 PTPRE THBD PID1 KL PCSK9 TRPC3 FOLR1 FYN LPL EGR2 PDE1B RGS9 INPP5K CAV1 BAIAP2 FOSL1 AQP9 CDH13 MYD88 VAMP2 C5AR1 PRKAR1A TGFBR3 CD9 RFTN1 RHOA DNAJB14 PDE2A EDEM1 CD36 ANXA1 MIR146A ATP2B1 DNAJC18 RRAGC ADA RAP1A BTG2 ANXA5 KLF10 CAV2 IFNK ADIPOR1 PPP2R2A PPP3CA NR4A1 ADRB2 NFE2L2 NDEL1 LAMTOR3 CRK SFRP1 ZEB1 ARHGEF2 EPM2AIP1 PDE4D ATP6V1H MTHFR TMEM38B ATP6V1B2 FOXC2 IL10 ROCK2 STAT5A RAB12 FOXO1 SGTB SRSF5 BIRC2 SORBS1 RNFT1 PTAFR KLF4 RRM2B ROCK1 KLF11 BCHE SOCS2 ATP6V1D SOCS5 ABCC4 UBQLN1 ATG7 SSH1 NFKB1 CDKN1A PDE3B P2RY2 SIK2 VIM SELL ATP6V0D2 TLR4 FCER1G PER1 DUSP1 RNF139 PIK3C2A WFS1 GNAQ GNAI2 TBC1D4 BACE1 ACTR2 MMP19 GNRH1 BTG1 USP25 SLC25A33 PDK4 KANK1 MYO1C SLC8A1 ADCY2 AREG IL6 PSEN1 SOCS3 APPL1 RAB8B JUN STAT4 NOTCH1 CPEB4 GABPA RAB31 USO1 HRH1 ATP6V0B DUOX1 JUNB PALM RAPGEF1 DHX15 CCR7 PIK3R1 UBAC2 PRKCE GRB2 CREB1 RAB8A PRKACA HOMER1 RALB SLC3A2 FOS ATP6V0D1 RHOQ PELI1 KLF2 CACYBP FOXO3 PKD2 SRSF6 PRKCG TREX1 FOSB MARC2 HNRNPD IRF5 SORT1 STXBP3 PEA15 SRSF4 GLRA3 FPR2 PDE12 GNAI1 ATP6V1A MIA3 PIK3C3 IRS2 ATP6V0C SLC8A3 CD81 GLRA1 BAG6 KYNU CRY1 ACTN2 RGS2 KAT2B PDE4B TSPO JUND ICAM1 SESN1 VGF HTR6 ARRB2 TIAM1 CXCR4 SEC61B EPHA4 RIPK2 NLRP3 ACTB IPO5 MBD5 SREBF2 FDX1 SIN3A NFKBIA MARC1 RAPGEF3 ADORA2A EDN1 PTEN DNAJB9 P2RX1 LDLR CCND3 GRB10 IQGAP1 ATF4 PMAIP1 SMPD1 CYBA EPG5 ATP6V0A1 HERPUD1 KLF15 ACVR1C EGR1 UBR2 GHR CDKN1B CNR2 UBXN8 KCNE1 ZNF106 HMGCS1 NR4A2 MAPK1 CNGA3 ITGB1 TREM2	down	***
GO_MULTICELLULAR_ORGANISM_REPRODUCTION	0.0015451	0.0176353	0.4550599	0.2729437	1.362113	555	TSPAN8 TRIP13 TP63 BRINP1 SPATA24 SPATA25 MYCBPAP FOXA3 PPP1R1B RUVBL1 PMFBP1 CCNB1 WFDC2 NPAS1 DPY19L2P1 GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 SPP1 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 STC2 CYP27B1 NOX5 APOL2 SPINK1 CIB1 TDRKH MCM8 MAP2K6 SRPK1 RSPH1 ZSCAN2 OSBP2 CASP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A AURKA REC8 ODF2 SYCP2 POC1A DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 EGFR OAZ3 CGB7 HSF2BP OXTR BRIP1 SPAG8 PTGDR2 CCDC136 MEA1 ASF1B LRGUK MERTK PICK1 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 ADNP MTOR CTSV MNS1 ADAM28 IQCG MORN2 UBE2Q1 PCSK4 GAS2 TSSK3 MMP7 TEKT3 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 THRB ESR1 TYRO3 NR6A1 KDM3A PTN MEI1 ROPN1B BCL2L1 CATSPER2 BAD DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 GGT5 ETV6 PHC2 SH3PXD2B PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2	up	*
MIR548BB_3P	0.0005323	0.0077412	0.4772708	-0.2286493	-1.361704	513	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 ZBTB43 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 CPEB4 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA	down	**
ONKEN_UVEAL_MELANOMA_DN	0.0006585	0.0092054	0.4772708	-0.2306830	-1.361567	458	RAB11FIP1 SEMA6A ACP5 DLC1 EDNRB SECISBP2L LTA4H PTP4A2 DPYSL2 SIK1 FYN CD44 EMCN ST3GAL6 CAV1 PCOLCE2 ARL8B PRKAR1A NEDD9 LAMP1 LYRM4 RHOA TXNIP TBX2 UBL3 SLC3A1 ASAH1 ENTPD1 MASP1 CAV2 BFAR ABHD6 SERPINB9 JAM3 SIRPA ADRB2 HNRNPDL SPRY2 KANK2 PDE4D TIPARP EIF1B DUSP3 SORBS1 PXDC1 ZNF423 KLF11 DAB2 TJP1 TPP1 EPM2A PMM1 ID2 TLR4 CEP57 M6PR GCA MATN2 DSTN RSL24D1 DEGS1 RABGGTB CMTM6 GLB1 BTG1 PRCP SPIN1 VAMP3 ID4 RYBP PGD SNAP23 APPL1 LAMB2 MTMR14 BAG5 PIK3R1 CD83 MBNL2 GYPC COBLL1 SERPINB6 ATP13A3 NOL7 FSTL3 TSPYL1 CGGBP1 SNRK IP6K1 MCAM LMCD1 PTP4A1 FOXO3 ATG3 ING3 GNAI1 ATP6V1A TSPAN14 GALC NFYC PLSCR4 CSDE1 GABARAPL1 CSNK2A2 KAT2B PDE4B MBNL1 HSPA2 SLC35D2 WDR1 ALDH6A1 IPO5 GPD1L KPNA4 GLUL TIMP3 PTEN FDFT1 MTUS1 GTPBP8 DAZAP2 NRP2 RPL18A CREG1 LPAR6 EIF4A2 RNF13 BMI1 DNAJA2 CBX7 USP4 CRTAP SLC25A38 ATP11B CRBN EIF3L PRKCH TGOLN2 GPR153	down	**
GO_PHOSPHOLIPID_METABOLIC_PROCESS	0.0006565	0.0091877	0.4772708	-0.2368921	-1.360780	352	GPD1 LPIN2 PNPLA6 ABHD5 TEK PLA2G10 MBOAT2 TTC7B PCSK9 FIG4 LPL INPP5K PTPMT1 GPCPD1 PLEKHA1 INPP5A IDI1 CDC42 AGPAT4 FGR PLA2G7 SLC44A2 SGMS2 SERINC1 ABHD6 APOC1 PDGFA TMEM38B RAB14 FABP5 MTMR6 DGKE PIP5K1B ACSL3 KLF4 SOCS2 SOCS5 PLBD1 CDS2 PIK3C2A PLEK PAFAH1B1 PIK3R5 NUS1 PLCD1 EFR3A PI4K2A HEXB SACM1L CLN8 FLT1 DDHD1 SOCS3 INPP5B PLEKHA3 PIKFYVE MTMR14 MTMR9 CCR7 PNPLA8 PIK3R1 PI4K2B LPCAT2 IP6K1 PLCG2 PNPLA3 SMPDL3B CHPT1 TGFB1 DDHD2 VAV3 ENPP6 DPM1 FPR2 MTMR2 PIK3C3 CD81 GATA6 PLAA CSNK2A2 SERINC3 PLA2G15 FGF2 RAB5A PIP4K2A GPD1L CD19 CEPT1 KIT PTEN FDFT1 FAM126B LDLR	down	**
HOXC6_TARGET_GENES	0.0001179	0.0022172	0.5384341	0.2668229	1.360576	953	HMGA2 ATP10B PPM1H SYT8 DDX11 FOXM1 VWDE MYCBPAP LAD1 CEP89 PARPBP BDH1 AP3B2 ZMYND8 DDX11-AS1 CIB2 DDIT4 NUDCD3 NDC80 PLEKHH1 DEPDC1B METTL1 ZFHX2 CDK4 XKR9 HILPDA UBE2Z ANLN FLAD1 CEP70 YEATS4 TPX2 GAPDH FIGNL1 THTPA AGR2 LSR PMS2 ACY1 KIAA0895 VILL XPOT NCAPD2 ZWINT LRRC27 HAUS5 ZSCAN2 BZW2 C1orf220 NDUFB8 ZNF74 LAMC2 RPL39L PAQR4 SLFN5 F2RL1 RNF216P1 TRIM29 AP4M1 KNTC1 WASF1 CLHC1 CCDC77 TMEM184A CENPL APOL1 CBX3 TMEM177 SMARCAL1 MCM7 ZNF860 ANKRD19P CDCA5 WDHD1 PKM AIMP2 WDR60 LIG1 SIDT1 SPINT1 IFT172 PEX26 CENPO COX19 SLC25A39 AKT2 LRRC61 PKMYT1 ETFA FDXR COMMD4 NOL3 C2CD3 ERCC2 ALG3 TFCP2 TRIT1 RNF216 MSTO2P NCAPG2 FASTK NUSAP1 TMEM106C ANAPC5 ING4 SSBP1 CENPJ ANKRD54 AAGAB POC5 STX18 KCTD13 CMTR1 RNF181 ACTR3C TRIM41 LARP1 PDK1 CPNE1 POLR1C PSMG3 TNPO2 TRIM7 LINC00649 USP42 SF3B3 ATAD3A NOP2 RNASEH2A LZTR1 UBN2 ZNF692 MAP3K14-AS1 MYO19 SLC35C2 TAPBPL YDJC GSS ADAT1 ALDH7A1 NMRAL1 SNRPA RAD9A YIPF3 ARHGAP32 COG2 ZMAT5 IQCG COX7C FBXO15 ZNRF2P1 ENAH CENPQ MSRB2 CSNK1G1 MEGF8 OS9 MRPL4 PKP4 ACAD10 AGPAT5 ITFG2 MAPK10 STX18-AS1 LRWD1 NDUFA13 TRIM32 CD27-AS1 COG4 SYNGAP1 IQCH CDK13 ATAD5 PPME1 RBM33 TMEM232 NAIF1 YARS2 NIF3L1 RAD50 CCDC137 KDM3A BAZ2A SASS6 RNF187 CLDN12 LIMA1 CPSF4 TMEM106B CA11 EFHC1 RRP9 ALKBH4 PPP6R1 TRIM56 GID8 EML6 NOB1 LANCL2 CACNB3 ADD3 ZBTB9 MRPL51 LINC00471 WDR27 LRRC46 WDYHV1 SH3TC2 DDX55 ATAD2 ALG8 ZNF622 SUV39H2 MICAL3 AMN1 ZNF212 SMARCA4 NTMT1 PRR11 HDLBP GABPB1-AS1 GTF3C2 DDX54 SNRPD2 POLR3B GTPBP2 PDAP1 ICK INO80E OSBPL10 TMEM44 RAD51 ZWILCH KCTD21-AS1 PPP6R2 GTF3C5 SUPT3H ZNF121 SNRNP200 FAM83E NUBPL UBAP2L ZNF131 PNKP RELL2 XPC ANKMY2 DNAJC14 DNAJC10 ALG1 GGCX GDPGP1 TMEM9B-AS1 RANBP3 MRPS27 CYSTM1 ARMC10 RAD1 DDB2 RABL6 NLGN1 PIAS4 BRSK2 FAM222B PPP1R14B PTPN13 ACTR5 BRIX1 SETD5 RAD51-AS1 ALKBH2 CLNS1A RNF14 FAM47E TOMM7 INO80B ZNF740 RPL23A SETD1A WDR55 MED22 MUS81 MBTD1 DEPDC4 PPP1R13L METTL4 SH3RF2 UTP18 CRAT ZNF598 NIT1 TMEM259 ZC3HC1 RBL1 APRT PPP2R5E HINT1 FOXP2 PSMB10 CES2 SDHAF1 USP35 GGA1 TOMM40 SNHG17 MAD2L1BP SLC4A1AP TYMP TLCD1 PIWIL4 MRPL45P2 CRYZ TEFM CCDC6 ARFIP2 MTR CXXC1 SLC27A5 TTPAL CACTIN IMP3 MAP3K5 ZNF524 HDAC3 GGA3 ELL3 HNRNPAB TIPIN MTF2 TTC13 CDH24 PC MCCC1 ARHGEF26-AS1 UVSSA SWSAP1 HENMT1 PAN2 SAP30L DHPS DDX49 PRKAB2 SLC12A9 MAEA SCAND2P NUP37 KIF3A PAWR PACRG CABYR PTPN23 ZNF691 IPO4 ZNF839 XRCC6 OIP5 HM13 COA6 ZNF473 SKA2 ABCB8 C1orf43 WDR12 VRK3	up	**
GO_CELLULAR_RESPONSE_TO_LIPID	0.0006062	0.0086197	0.4772708	-0.2288203	-1.360066	488	SLC6A4 CXCL3 KMO ZNF366 RAMP3 IL1A SASH1 EDNRB SCIMP PPARG ADTRP CD55 IL1B PID1 INSIG1 LPL LY86 CRY2 MYD88 TBXA2R NR3C1 IL1RN TRIB1 CASP9 RHOA BRINP3 CD36 ANXA1 MIR146A SSTR1 ATP2B1 CARD16 TNIP3 FZD4 LITAF FOXP1 EIF4E NR4A1 SIRPA RB1 TRAF6 SFRP1 WNT3A KANK2 HNRNPU PDE4D NODAL IL10 ROCK2 FOXO1 CASP1 PTAFR KLF4 REST ID3 KLF9 DAB2 ARNTL LY96 CCL3 NFKB1 NR1D2 KCNMB1 CXCL2 IRAK2 VIM AXL TLR4 LBH PER1 INHBA CPT1A CYP26B1 IL24 NCOA1 PIAS1 HCK PDK4 UFM1 WNT9A FAM107A CREBRF CD80 ADCY2 IL6 RWDD1 DDX17 CARD8 DNAJA1 PTGER4 IRF8 DDX5 PRKCE CREB1 PTGER2 MALT1 MT-ND3 CXCL5 EGLN2 ADNP2 MAPK8 WNT11 DDX18 HNRNPD EPHA3 TGFB1 NR2C1 CD6 TGFB1I1 GNAI1 CD86 PIM1 PLSCR4 KLRC4-KLRK1 WBP2 CRY1 PLAA PDE4B TSPO RXRA NR2E3 ICAM1 IL18 ABL2 TFPI ARRB2 OSR1 RIPK2 NLRP3 PTCH1 HAVCR2 FDX1 NFKBIA RET EDN1 KLRK1 RORA LDLR NR3C2	down	**
ZSCAN31_TARGET_GENES	0.0004724	0.0070176	0.4984931	0.2684553	1.360041	769	PDE11A KIF20A GPR89A DNAH2 ZDHHC4 NUP107 ABCA17P DOC2A C17orf75 FBXO27 PDCD2L ZFP62 HILPDA SDHAP3 NABP2 TTC26 NUF2 PTTG1 TIGD1 LSR DNAH14 ZNF107 MPPED2 DCTN2 WDR90 NME1 GOLPH3L MANSC1 ASAH2B ITGA2 BZW2 ZNF607 NUDT1 STRA6 SMARCC1 KIF23 C9orf116 CUL7 LINC00665 PAFAH1B3 CCDC77 EME1 MYO10 VANGL1 ATR GTPBP3 WDR78 RSRC1 COASY PDCD5 AMACR ZNF146 MRPL27 PHKG2 FANCD2 EMG1 TARS2 WDR60 OAZ3 POLR3C EME2 TRMT61B ACSF2 CSRNP2 THAP10 EEFSEC PHB COMMD4 MBOAT1 MNAT1 SLC25A10 KCNJ2 SKP2 TTBK1 NRSN2 CDKN2C TMEM106C SUPT5H CBX5 SRRM2-AS1 KCTD7 ZNF260 ZSCAN25 GMNN POLR3K STX18 VANGL2 KCTD13 DNA2 MRPS2 SLC25A13 FAM98C ENPP3 KLHDC9 TMEM79 TTC23L NAPEPLD UCKL1 CENPP WDR24 SUSD4 STK11 C3orf67 SNRNP25 GIPC1 ACBD6 GNPAT SATB2 SMG5 NDUFA11 FAM47E-STBD1 GALK2 TRMU MTOR NMRAL1 RBFOX3 AARSD1 DHRS4-AS1 MRPS34 LLGL2 CCDC151 C19orf12 PIGG HIRA COPS7B FBXO4 ZNF544 C1orf131 JMJD4 MLEC LINC00662 STX18-AS1 TMEM186 ASNS S100A13 FAM207A PRRG2 ZBTB45 SCNN1G TRAF3IP1 CLTB CABLES2 CDC7 NIF3L1 PROCA1 EFCAB7 TIMM13 CPSF4 BRD8 EFCAB10 VPS25 CCDC30 ZNF428 DUS1L FBXO22 MRPS23 PPP6R1 ZNF223 C16orf58 RAI14 NOSIP TMEM147 ZNF783 NMNAT1 HEATR1 SNRPD1 SIRT5 RABEPK SNAP47 ADD3 C1orf109 GINS3 NHSL1 NDUFS7 POLR2I YIPF2 ETV6 SUOX IGHMBP2 ZNF780A DDX55 MST1P2 COPZ1 NME1-NME2 B9D1 MCRS1 NCDN ZNF195 HEATR5A DENR POLR3B PCBD2 CDK5RAP1 VPS33B TRIP4 FBXW11 PFKM PPP6R2 COPA MRPL9 MRPL21 SNRNP200 CHD3 LINC00240 RHOT2 TMEM101 NUBPL TBCB AURKAIP1 ZNF793 ANKMY2 ADRM1	up	**
MIR579_3P	0.0007183	0.0098269	0.4772708	-0.2325099	-1.359315	411	GCOM1 MBOAT2 ZBTB34 MMRN1 MED4 CLEC12B LONRF1 NEDD4L QKI NTM KCNN3 DSCAML1 MOB1B TMX4 DNAJB14 ZBTB4 WWC2 NCEH1 B3GNT5 UBL3 SLC25A17 ARSB RAP1A SWT1 BZW1 SERINC1 SPIRE1 GLS CAV2 CAMTA1 SLC7A11 GLDN TBC1D9 ARRB1 DGKE SORBS1 LIMS1 KLF9 ANKRD10 KLF7 MYRIP SEC24B ERP44 LAPTM5 NPAS3 AQP4 PTGER3 CPT1A PTCHD4 GNAQ PRICKLE2 NUS1 TBC1D4 FAM76B NCKAP5 IKZF5 CLIC5 GPBP1 PDIK1L LRRTM2 PHACTR2 NEK7 PLEKHA3 OXNAD1 GABPA APBB2 IPO7 SKIL PNPLA8 PIK3R1 IRF8 FRYL COBLL1 HSD17B12 SH2D4B ZNRF3 UVRAG OGFRL1 DENND4A CDK14 AGFG1 RHOQ AGPS CALM1 YTHDF3 USP7 PSMD12 HSF5	down	**
REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM	0.0001100	0.0020949	0.5384341	-0.2179346	-1.358678	685	EREG IL17RB IL1A HMOX1 TEK IL1B NUP54 RAPGEF2 KL FYN CD44 CCL3L1 SAMHD1 RASAL2 MYD88 VAMP2 S1PR1 FGF10 MEF2A CDC42 IL1RL1 IL1RN PSMD5 CBL IL23A CD36 ANXA1 EIF4A1 TNFRSF8 CLCF1 HBEGF ADAM17 LIFR RAP1A RASGRP4 MAP3K8 IFI30 RANBP9 PAQR3 LCP1 EIF4E GATA3 IL18R1 TRAF6 HNRNPDL LAMTOR3 CRK SPTBN1 ZEB1 MCL1 PDGFA KPNA5 PTPN12 IL10 MAP2K3 STAT5A ARRB1 DUSP3 CCL22 FOXO1 BIRC2 CASP1 TRIM46 TNFSF12 PTAFR PSPN TNFSF15 STX3 SOCS2 SOCS5 CCL3 NFKB1 CDKN1A PDE3B ITGAX NKIRAS1 EPGN CXCL2 IRAK2 VIM CCL4 DUSP1 PPP2R5C PPP2R5A IL7R CA1 KPNA3 HLA-DQA1 IL24 MARK3 VWF PIAS1 HCK RPS6KA2 CD80 CNTF PPP2CA AREG IL6 SOCS3 IL2RB OASL JUN PSMA1 STAT4 JUNB IFNGR1 JAK1 DUSP8 RAPGEF1 GSTO1 PIK3R1 IRF8 GRB2 CREB1 OSM RPS6KA1 PRKACA TCP1 TNFRSF9 YWHAZ FGFR4 FOS UBB PELI1 CALM1 KLB TNFSF13 PSMD12 FOXO3 MAPK8 IRF5 PPP2CB NUP153 TGFB1 HNRNPA2B1 PEA15 TEC PDE12 DUSP5 IFNAR1 PIK3C3 CD86 IRS2 PIM1 SOD2 CCR1 ACTN2 IFNLR1 CCL20 PITPNA ICAM1 FGF2 IL18 IL18RAP LAT ARRB2 CEBPD HSP90AA1 TAB2 RIPK2 ARIH1 HSPA8 ACTB SP100 HAVCR2 BRWD1 PSME4 NUP98 KPNA4 CUL3 NFKBIA RET KIT PAK2 DUSP7 TNFSF9 FGFR1 RORA NRG1 PSMD6 MT2A IQGAP1 PSMD9 IL16 EIF4A2 NUP160 CNN2 EIF4G2 IRF2 CSF2 UBE2V1 EGR1 CD70 CSF2RB GHR TNFSF8 DUSP6	down	**
MIR520B_3P_MIR520C_3P_MIR520E_3P	0.0020529	0.0218807	0.4317077	-0.2444791	-1.357585	286	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 SLC16A10 PLAG1 ARHGEF17 CFL2	down	*
DIDO1_TARGET_GENES	0.0000225	0.0005539	0.5756103	0.2641812	1.357496	1321	PCSK6 GPR89A RUVBL1 CEP89 DEPTOR TFAP2A NUP107 ABCA17P NEK2 COIL XYLB C17orf75 GBAP1 COA1 NUDCD3 NDC80 TSFM PRIM2 SRGAP3 THEM4 CDCA7 ECE2 ZFHX2 CDCA2 NOL12 NABP2 EIF2B5 FLAD1 TTC26 DGCR8 NUF2 ACAD9 WDR70 GOLGB1 ZNF221 THTPA KNOP1 TIGD1 UMPS DTL MCM8 MIS18A ZNF3 DZANK1 MRPS35 COQ3 AOC1 UQCC1 INTS1 FAM220A SYT12 NME1 AARS2 TOP3B WDR62 POLR3A TMEM41A KCNH2 NEURL2 EXO1 ZNF391 BBS1 BOD1 QTRT1 KIF15 PCCB AP4M1 FBXW9 FRS2 TIGD4 EXOC4 RPL32P3 AURKA EME1 NUP155 METTL7B ATR YKT6 GTPBP3 LARS2 MCM7 CENPW COASY DPCD RBM28 NSUN2 SETDB1 RAD54L MRPL3 KLHDC4 MRPL27 FANCD2 BLOC1S1 SNHG11 CCDC58 EMG1 ZNF785 TARS2 FAM162A OAZ3 POLR3C EME2 BMS1P1 MORC2 BCL2L2-PABPN1 C7orf50 PEX26 HSF2BP TRMT61B AHCY COX19 RAD51AP1 GEMIN7 EEFSEC ZNF507 COMMD4 FADS2 ALG3 MNAT1 TFCP2 SRRM5 COQ9 PPP1R37 RECQL5 PES1 RNF216 CDKN2C HPS4 DDX51 HARS2 MRPL37 LRRC6 RNPC3 CDK12 MDH1B FAM135A ZSCAN25 STX18 MCAT WDR31 BPGM DHX33 ENPP3 KLHDC9 FEN1 NUP205 TMEM79 PSMG3 TNPO2 POC1B THAP8 MTBP ATAD3A SNRPE HMGXB3 ZNF623 VPS72 CENPP WDR24 SRD5A1 DNAJC7 EFTUD2 MZT2A GOLGA3 ZSCAN9 ELMOD3 MZT2B CEP63 TELO2 INTS7 ZGPAT BBS5 ARFRP1 CCDC142 ZSCAN21 NPHP1 CCZ1B SMG5 WDR53 NDUFA11 C19orf47 NFS1 VPS41 CNOT2 DHX40 TSNAXIP1 TRMU ADNP MTOR NMRAL1 ZNF133 POLL MRPS34 CCDC151 DHODH PIGG HIRA TIGD6 SUDS3 FBXO15 TMEM237 COPS7B UBE2Q1 ZNF417 ADAR JMJD4 MLEC CCDC146 IQCK TJAP1 STX18-AS1 GUSBP1 PRMT7 GFM2 CKMT2-AS1 FAM207A C12orf73 NUP85 FAM200A CCZ1 CCDC159 AAMP CCT7 RNF187 GEMIN6 EFCAB7 SUPT16H MDGA1 LSG1 CKAP5 PSMB3 ZNF502 VPS25 PALB2 STOML2 WDR34 CHCHD1 ASB6 FAF1 LRRC59 AP3M2 CLASRP GPATCH4 FAM50B FAHD1 MRPS23 UBXN6 POLR2J BAD CHTF8 ZNF558 MRPS33 ZNF223 METTL2B WDR83 PPCDC MED24 ZSWIM8 NSUN6 UTP20 ROMO1 GNG4 NOC4L NMNAT1 HEATR1 SNRPD1 MALSU1 SNAP47 DYNC2H1 MRPL53 LTV1 SLC35A3 SCYL3 RTEL1-TNFRSF6B RAB3D GINS3 POLR2J3 URB1 STMN3 NDUFS7 KATNB1 YIPF2 SUGP1 MED27 RRP36 DDX55 ATAD2 DUS2 GTPBP10 ZNF580 FARSA NDUFV1 NME1-NME2 RER1 PRPF18 MCRS1 ZNF212 RPS26 RBM42 DBNL BBX BANF1 RTEL1 MANBAL POLR3B MRPL55 ANAPC2 DOHH STAT6 CDK5RAP1 ABCF2 TTC31 WDR4 WDR77 PRPF31 CLUAP1 HOOK2 BMS1 TTC1 TRAPPC9 TRIP4 ZNF292 BRMS1 ZWILCH SEC13 TOMM40L PFKM MARK4 GTF3C5 MRPL9 KIAA0825 RPUSD2 NME7 FAM118B TMED9 TMEM101 ERBB2 UBAP2L ZNF131 CIAPIN1 PARG MAU2 PFDN4 POP4 SMPD4 ZMAT2 NDOR1 ALG1 ZNF205 TRUB1 MCF2L2 TMEM9B-AS1 ZNF526 LEMD2 BPNT1 SLC36A1 SNRPC TBL3 PIGL FBXO45 NCAPD3 CDKAL1 NELFA MRPL20 PWP1 SART1 RAD1 MRPL48 ZER1 NDUFB7 NAT10 TRUB2 LINC00888 CALU HEMK1 BRIX1 TRPC4AP FBXL18 ZNF562 ZNF629 POGZ CSTF1 RTN4IP1 INO80B EIF2D VPS26B DHDDS MAN2C1 SPHK2 METTL4 C12orf43 MED15 RANBP10 EIF2B1 PARL CDK11B ADSL RPL36 ZC3HC1 RBL1 ZNF514 ZNF688 APBA3 CYB5RL TNPO3 NFE2L1 GGA1 OPA1 AP2B1 PANK4 VAC14 ZKSCAN4 EDC4 SNHG17 MECOM MCEE TIMM10 PGAP3 SLC4A1AP NHP2 STARD10 COQ5 RAG1 CHD8 MTMR4 CRYZ TEFM AK9 RPLP0 ALS2 CXXC1 SLC27A5 ZNF805 CACTIN EHMT1 ZNF524 SEC24C KLHL12 CCDC86 ETAA1 TIPIN RETSAT MTF2 TTC13 TXN2 FAM149B1 SLC7A6OS C1orf74 ARL1 PSMD3 ZC3H18 STRIP1 CALM3 BNIP1 KMT2D METTL17 MEN1 WDR25 SLC44A1 C15orf40 PRKAB2 NBAS POLD3 CCDC124 EBNA1BP2 COQ4 IPO4 METTL9 ZCCHC7 BECN1 PSMD8 COX6C TMEM203 MPLKIP ABCB8 C1orf43 NDUFA9 KLHL20 GPR137 ORMDL3 CLTC ACCS ZNF396 SLC39A3 TSEN15 DCTN5 C5orf51 MRPL13 RABGGTA EDC3 GATM KCTD16 RAD51B RFC3 NVL GLB1L MRPL33 ZNF335 JRK RFC4 IFT74 REXO4 SUCLG1 COX16 ATXN2L CHFR VTI1A ZNF546 POLR2J4 USP31 RRP1B HSD11B1L C1orf35 ZBTB17 ZNF200 ITGB3BP TUBGCP6 DDX31 WDR92 MAPKAPK5 TIMM23 TSKU PHAX PRKCSH VMAC DRG2 DNAJC16 UBE3B TARDBP POLR2C SLC35B1 LZTFL1	up	***
GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_UP	0.0051807	0.0439702	0.4070179	-0.2542345	-1.357295	185	EPAS1 GPATCH11 PDLIM2 PECAM1 HVCN1 FBP1 KLHL8 BAIAP2 MTMR10 CLEC10A ELMO1 NCF2 NFATC3 SPCS3 ASAP1 CD33 ZBTB8A SLC19A1 ZYG11B ARRB1 LIMS1 ZCCHC24 ATL3 ARHGAP9 TM6SF1 PINK1 UBASH3B CNRIP1 ARHGDIB FOXN3 TBC1D5 RGS18 CYB5R1 HMBOX1 RAB31 BAG5 GLIPR1 GMFG CTTNBP2 SRSF6 DOK3 NDUFA5 KCTD10 RXRA MOB3B ATP9B METTL21A ALDH6A1 GPD1L FOXJ2 DUSP7	down	*
MIR373_3P	0.0010143	0.0128472	0.4550599	-0.2450602	-1.357249	280	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST ANO6 MIER3 TRIM36 IRF2 ZFYVE26 PLAG1 ARHGEF17 CFL2	down	*
AEBP2_TARGET_GENES	0.0002549	0.0042282	0.4984931	0.2660308	1.357201	981	PRR15 CEACAM1 FAM227A PPP1R1B HJURP RUVBL1 CEP89 TICRR GMDS GPT2 ZNF273 C1QTNF6 ZMYND8 CHEK2 ZNF12 CCNB1 CENPF IGF2BP3 DROSHA C17orf75 HOXB6 C21orf58 SEMA4B GGCT TTF2 CHCHD6 PHF14 PIF1 RGMB-AS1 MRPL46 CDCA2 AGFG2 ANKZF1 FLAD1 SAP30L-AS1 DGCR8 IFT27 CENPA ACOT8 TPX2 MCM4 STRIP2 LSR TYMS EIF3B PLS1 TDRKH SGK2 LIPE-AS1 CAND1 RCCD1 FSTL4 AVL9 ZWINT LRRC31 GOLPH3L CEP250 TJP3 WDR62 POLR3A BZW2 RAB11B-AS1 STAP2 MRPL15 AP4M1 WASF1 PAFAH1B3 MAP3K13 TPBG BRAT1 CCDC77 TOP2A EXOC4 CCT5 IQCD HHAT SMARCAL1 MCM7 TPCN1 LIPE PRKDC RHOBTB3 TMEM45A HOXC6 AMACR MCM3 CDC25C PFN2 ZNF785 TARS2 CHD6 SARS2 ORC6 ACTL6A CBY1 ABCB9 DNAAF3 SPC24 MRPS11 SPATA17 LRRC61 BRIP1 DDR1 OGFOD2 SLC35E2B ARL16 C4orf47 SRRM5 TULP3 CKS1B MRPL36 NRSN2 FRMD5 ASF1B ANAPC5 CDK1 PABPN1 WDR5B SSBP1 CCDC61 RFWD3 PLA2G2A PICK1 RBCK1 POC5 ACP6 UNG VPS28 ZNF815P DGAT2 AP5Z1 PMEL RNF181 ACTR3C ZNF789 ANAPC7 SPAG5 LINC00649 THAP8 TTC16 NOP2 VPS72 CENPP ZKSCAN5 DNAJC7 IFT52 KPNB1 HYKK GIPC1 DNMT1 ZNF687 CEP63 CDC23 AKR1E2 PDCD11 SATB2 DCAKD SPG7 VPS41 SLC26A2 GALK2 MTOR DNAJA3 PUS1 TRIM9 FHIT UROS DOK4 MORN2 COPS7B DPH2 TK1 RHBDD3 AKAP8L HDAC1 MLEC OS9 ANP32E DAP3 LIN37 ZSWIM3 ASNS TM9SF4 DNMBP AAMP NAIF1 CCT7 NR6A1 RMND5B KDM3A CENPK TADA3 ACBD5 LSG1 LIMA1 CKAP5 PWWP2A CDC20 DGKA ORMDL2 RPRD1B CENPM CA11 SIRT4 GBF1 AP3M2 BCL2L1 NOL6 ABCA7 KRT8 ARVCF HOXA3 KDM4B EML6 RPL7L1 MED24 PRMT1 RPPH1 ANKRA2 UIMC1 MALSU1 C5orf22 FAM161A LANCL2 PYGO2 SRSF1 AATF KATNB1 DOLPP1 DUS4L POLR2I CREB3L2 RGMB LSM4 STK35 MVP CEP152 COPZ1 SPSB3 MICAL3 COG5 CYTH2 NCDN RBM42 ULK4 PRR11 BBX FKBP9 VDAC1 TXNL4B DOHH ZNF436 CEP164 NUBP2 PPFIA3 GTF3C5 SNX8 TBCB ALKBH6 BCAS3 POLR1B BCL6 TMEM260 CENPE POLR1A ANKMY2 PFDN4 FRMD6 NMT1 HGS TIMM44 FIS1 ZNF526 ZNF354B MRPS27 SIGMAR1 PPIA UBE2C PNN TTC9C PTOV1 SFXN5 DCAF11 ZSCAN20 TMEM38A MRPL48 COX6B1 STK11IP TTLL5 SCAF1 SART3 TMEM161A ATP6V1E2 MSANTD4 ANKRD11 CYB5B ZNF629 PHRF1 PARP2 COPE SUMF2 TMEM62 RPL23A DHX57 MORN4 PDXP MBTD1 ZNF678 PPP1R13L SPHK2 PDK2 SH3RF2 UTP18 TRAFD1 AKAP9 PCNT ZC3HC1 SRI TBC1D10B FBXO5 ABHD2 NFE2L1 MEGF11 TMPO ZNF774 MCEE ZNF414 TRAF7 NHP2 GLRX5 ZNF77 COQ5 RAG1 MPZL1 MTMR4	up	**
GO_REGULATION_OF_BODY_FLUID_LEVELS	0.0006112	0.0086807	0.4772708	-0.2339765	-1.356453	386	CLEC1B EDNRB ADTRP GATA2 F2RL3 ADCY9 P2RY1 EMP2 ADCY4 THBD RCOR1 TRPC3 FYN MMRN1 INPP5K CAV1 TBXA2R FGF10 PRKAR1A CDC42 CD9 GAS6 CYP4A11 HPS5 PEAR1 HEG1 CD36 SH2B3 ADA FOXA2 ENTPD1 CSRP1 HSPB1 ANXA5 SLC7A11 GATA3 NFE2L2 WNT3A PDGFA FLI1 STAT5A ARRB1 DGKE PTPRO PLAUR THBS1 SOCS2 MAFG MPL NPR3 ITPK1 DOCK9 P2RY2 AQP4 SELP AXL HPSE TLR4 CAPZA2 FCER1G PLEK WFS1 GNAQ UBASH3B CYP26B1 PIK3R5 GNAI2 C4BPB MAFF VWF NCOA1 PROCR SRF PRCP METAP1 ADCY2 IL6 AQP3 ENPP4 PIK3R1 PABPC4 PRKCE CREB1 NPR1 PRKACA DOCK8 AP3B1 YWHAZ CD34 PLCG2 EHD2 PRKCG SLC4A5 MYL12A DGKG STXBP3 EHD1 VAV3 TEC NLRP6	down	**
MIR6083	0.0041883	0.0374839	0.4070179	-0.2493922	-1.356343	222	SMAD6 FOXF1 GCSAML C18orf32 KCTD9 HSD17B11 CCDC88A SEC22C QKI MANBA SGMS2 RANBP9 SLC7A11 MED26 SETD3 TMEM38B ATP10A CPED1 ROCK2 TBX4 ZFAND5 TMED5 NPR3 RNF139 SMAD7 CDKN2AIP ACTR2 PIAS1 HCK PPIL4 PRDM11 PDIK1L SENP3 NEK7 ESD RNF141 CNTN3 PPA2 SHOC2 RABGAP1 PTGER4 IPO7 SP3 ACKR3 PI4K2B ATL2 SNX1 FSD1L NIPSNAP3B SLC35F1 FEM1B CDC37L1 KHDRBS1 MAP3K2 ANKRD13A CRY1 PCCA PRDM8 INO80D IQSEC1 CXCR4 ARL14EP CREBBP STK4 MAFK SCUBE1 CHCHD7 RORA FAM13C	down	*
GO_ORGANELLE_LOCALIZATION	0.0027226	0.0269870	0.4317077	0.2721018	1.355414	544	KIF1A CEP72 SPICE1 CPLX2 CEP89 RPGRIP1L AP3B2 PDCD6 NEK2 CCNB1 CENPF UCHL1 C17orf75 NDC80 RAB3IP MKS1 BET1 BRSK1 KIF14 ASPM PCLO MSTO1 COL7A1 CEP70 PLK1 NUF2 CDCA8 CENPA ESPL1 DYNC1I1 CDT1 DCTN2 SPDL1 HAUS5 CEP250 DLG1 KIF23 SYTL2 BOD1 BICD1 COPG2 COPG1 KIF3B BRAT1 FBF1 EXOC4 AURKA ODF2 YKT6 SFI1 KIF2C MAD1L1 CDCA5 GPSM2 BLOC1S1 AP1M2 SLC9A3R1 MAD2L1 KIF3C RAB13 C2CD3 SPRY1 PARD3 MYO1A PSRC1 MARK1 NUSAP1 NSF IQCB1 CDK1 CROCC CLMN CEP97 KIF5A CD300A SNX4 CENPJ AP3D1 ATP2A1 SUN1 SYN3 TCTN2 CDH3 SPAG5 KXD1 SAPCD2 TRAPPC12 FGFR1OP STK11 KPNB1 EIF6 MYO19 CEP63 BBS5 PLEKHM1 PABPC1L CEP192 NPHP1 CDC23 TUBG1 DLGAP5 SEC16B NINL LLGL2 KIF22 DNM1 CENPQ SYT1 S100A13 MEI1 CKAP5 KCNB1 TMEM106B GBF1 TCTN1 AP3M2 PPP6R1 CHMP4C CDK5RAP2 DYNC1LI2 RAB15 HAUS6 RABEPK CLUH LTV1 RAB3D KATNB1 HAUS4 NEFH GOSR2 CEP152 RAB34 NUP62 B9D1 ATP6AP1 ALMS1 SYBU CEP164 VPS33B TRAPPC9 STK25 SEC13 PPFIA3 CHMP1A MARK4 NLGN2 TRAK1 CHMP2A CDK5 TMED9 LLGL1 RHOT2 NTN1 GOSR1 CENPE DTNBP1 GOLGA2 TSNARE1 SYNE2 RASGRP1 RRS1 DNM1L WIPI1 NLGN1 CLASP1 BRSK2 TMEM201 KIF24 PLIN5 TRAPPC6A ESYT3 SNAP25 F5 CEP290 CHMP6 VPS18 DYNC1H1 SPHK2 TFG PLK4 PDZD8 AKAP9 PCNT	up	*
MIR4307	0.0019612	0.0211140	0.4317077	-0.2376775	-1.355180	337	TRIM71 HSPA12B COL25A1 PHACTR1 PTP4A2 BTNL9 RUNDC3B ARRDC4 TMEM170B CGNL1 FLVCR2 OTUD4 TEX2 ZEB2 KCNAB1 CNST RAB33B HIPK3 CAV2 SLAIN2 RGCC SRSF2 PDE4D TBX4 PPM1K LIMS1 LIN7C FAM76A SETD9 SLC12A4 ROCK1 UBQLN1 SSH1 GPR85 CDS2 HNRNPUL2 CTBS AQP4 CYP20A1 CPT1A CMTM6 EFR3A LIN7A ZDHHC20 LIN54 SACM1L SPIN1 VPS37A PHTF2 PHACTR2 USO1 PTGER4 IPO7 ENPP4 GLIPR1 CD83 MBNL2 IDS CGGBP1 HIVEP2 NAA16 WNT11 CHORDC1 EPHA3 DDHD2 LSM6 PDS5B VAMP4 CNOT7 PCDH17 COL15A1 ANKRD12 NPTN RIMKLB GPR18 EMC4 INO80D PET117 GEM YAF2 C22orf23 DCTN4 ACAP2 TMOD2 HSPA8 TDRP MEGF9 G3BP2 ZDHHC21 STAM2 BCAT1 JMJD1C SCAI	down	*
GO_POSITIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION	0.0001023	0.0019718	0.5384341	-0.2133972	-1.355143	822	FFAR4 RTKN2 HCRTR1 GPR17 EREG RAMP3 IL1A SASH1 HMOX1 TEK SCIMP GLIPR2 IL1B C18orf32 F2RL3 CAT P2RY1 GPR65 RAPGEF2 BMPER BMP2 ENG KL FYN CD44 CCL3L1 BAG4 CAV1 CDH13 MYD88 ADCYAP1R1 C5AR1 HMGCR FGF10 CDC42 MIR27B MARCO VAPA IL1RN GAS6 CBL IL23A FGR RHOA ZEB2 AVPI1 CD36 JPH2 SLC44A2 RRAGC CARD16 HBEGF ADA RAP1A RASGRP4 MAP3K8 FZD4 LITAF CAV2 CAMTA1 GATA3 ADRB2 IL18R1 TRAF6 LAMTOR3 CRK SPRY2 MAPK8IP1 TCF7L2 TXN MCL1 PDGFA NODAL SORBS3 GPR4 MAP2K3 ROCK2 ARRB1 CCL22 AGO3 BIRC2 EPOR SDCBP NPNT CASP1 LIMS1 SLC46A2 ROCK1 TNFSF15 THBS1 SPAG9 PDE8A CCL3 PTPRC EPGN IRAK2 SELP AXL HPSE CCL4 TLR4 MIR24-2 XCL2 PINK1 HTT PIK3R5 BCLAF1 GNAI2 CALM2 MAPRE2 SIAH1 TGFB2 TMEM9B ARL6IP5 PRKRA CD80 FLT1 AREG IL6 DNAJC27 GPR61 PSEN1 HCST JUN NOTCH1 ZFP91 ADRA1A HIC1 PDE5A RAC2 MAP4K4 HSPA1B RHOG SHOC2 RAPGEF1 GSTO1 CCR7 SKIL PIK3R1 ACKR3 DDX5 PRKCE GRB2 GPR183 OSM MALT1 NPR1 RC3H1 RTN4R REL TNFRSF10B RASSF2 NDST1 FGFR4 GPR37L1 UBB PELI1 LMCD1 CALM1 KLB PKD2 CD74 WNT11 PIK3AP1 SPOP TIMP2 TGFB1 PEA15 SMCR8 FPR2 MIR23A SH3RF3 DUSP5 CD86 IRS2 MAP3K2 RELL1 TERF2IP CD81 NQO2 CCR1 NPTN GPR18 SERINC3 CCL20 ICAM1 FGF2 IL18 MIER1 FKBP1A HTR6 ARRB2 RTN4 TIAM1 CXCR4 HSP90AA1 EPHA4 TAB2 RIPK2 SIK3 HAVCR2 S100A4 BOK MAP3K4 CD19 RET COPS8 KIT EDN1 PTEN DUSP7 SYNPO2L FGFR1 NRG1 NR3C2 IQGAP1 LPAR6 SFPQ PUM1 RNF13 BANK1 FLT4 PMAIP1 SPHK1 UBE2V1 GREM1 CDON C5AR2 GHR DUSP6 CX3CR1 C5 MAPK1 ICOS ITGB1 TREM2 NCF1 RB1CC1 S100A8 FPR1 NDFIP1 PIK3CG CALR MUL1 IFIT5 WNT5A LAMTOR5 UBE3A MAP4K2 UBE2N KIDINS220 BCL10 TRIM13 AKAP12 GPR55 HMGB1 DDX21 PDE6G EP300 CD3E	down	**
MULLIGHAN_MLL_SIGNATURE_2_UP	0.0013977	0.0163977	0.4550599	-0.2332382	-1.354629	371	SIRPB1 PECAM1 OSBPL1A FBP1 SNX10 CAT ADCY9 COQ2 IL1RN LAMP1 PILRA DPEP2 SPG21 BEST1 PBX3 LCP1 DACH1 LAIR1 TOR1AIP1 SIRPA ADRB2 GRN CES1 SRGN HNRNPU SPI1 ADARB1 EVI2B PPT1 CASP1 PTAFR PLAUR FUT7 GAA MVB12B ARNTL CEBPA ATP6V1D TPP1 LAPTM5 PMM1 ITGAX CTBS ID2 CD302 RECK M6PR PLEKHB2 CD300C ACTR2 TDRD7 HEXB HCK RAB6A ARL6IP5 PSEN1 RAC2 NXPE3 CSTA TMEM251 SDHD GRB2 MALT1 RPS6KA1 TNFRSF10B RASSF2 CLN3 TNFSF13 RBKS ATG3 ALDH3B1 TREX1 NKG7 TRAPPC10 WHAMMP3 FXYD6 TFEB ATXN1 MEIS1 CCR1 THAP11 KYNU CLASP2 MR1 MBNL1 RXRA PITPNA SELPLG ARPC2 SLC31A1 CDC42EP3 CXCR4 NLRP3 SCPEP1 S100A4 COMMD8 DUSP7 ABCA8 CCND3 IQGAP1 FEZ1 BMI1 SMPD1 KLC1 CYBA	down	*
GO_EXTERNAL_SIDE_OF_PLASMA_MEMBRANE	0.0023197	0.0239832	0.4317077	-0.2436178	-1.353898	274	FCN1 ACE PECAM1 GPIHBP1 BTNL9 CDH5 ENG PCSK9 FOLR1 CCRL2 CLEC12B CDH13 S1PR1 TGFBR3 IL1RL1 CD1C CD9 LAMP1 TGFBR2 ABCB1 CD8A HEG1 CD36 ANXA1 CD5 ADA CD33 LIFR ABCG2 ITGA5 CLEC14A ANXA5 ABCG1 ANPEP MS4A1 TMEM123 TFRC THBS1 ABCC4 PTPRC AQP4 SELL SELP TLR4 FCER1G KLRD1 IL7R CD80 IL2RB CCR7 ACKR3 CD83 RTN4R TNFRSF9 MCAM CD34 CD74 CCR4 CD1D CD6 CD86 PDCD1 GLRA1 KLRC4-KLRK1 IGHV3-23 CCR1 FCGRT MR1 CCR6 ICAM1 CXCR4 ITGAE CCR9 BCAM CD19 KIT CD1E CD3G SCUBE1 KLRK1 P2RX1 LDLR	down	*
MIR153_5P	0.0000202	0.0005068	0.5756103	-0.2147201	-1.352121	866	SLC24A4 EREG AKAP5 FOXF1 OSBPL1A RBMS2 ZC3H12C ATXN3 CLDND1 PTPRB TTC7B GPC5 ARRDC4 TMEM170B LPL OTUD1 LMO2 BACH1 DDX6 NEDD4L THAP2 QKI GPCPD1 ZCCHC2 PLEKHA1 C5AR1 MEF2A KBTBD3 RXFP1 NEDD9 VAPA TSHZ1 PSMD5 CD22 MOB1B FAM49A ACER3 PDCL ZEB2 ANXA1 NCEH1 B3GNT5 UBL3 SLC36A4 SLC25A17 ENTPD1 NAAA RAB33B BTG2 SERINC1 ZNF503 MS4A14 GLS CAV2 CAMTA1 DACH1 SLAIN2 PPP3CA AKT3 TMEM41B CWC22 PRDM16 TLE4 DGKE KCNMA1 DENND6A LIMS1 ACSL3 KLF4 PAQR5 RUNX1T1 RRM2B ZADH2 TMED5 STX3 GRK5 FBXL3 MYRIP PDE8A ATL3 C1QTNF7 MGAT4A C4orf33 RBMS1 NR1D2 M6PR CCSER2 DNTTIP2 ZMPSTE24 GCA DSE EXOSC8 CUL5 PEAK1 SLC6A6 KIAA0408 BCLAF1 NUS1 GNAI2 PDE1C TBC1D4 NCKAP5 CDKN2AIP ZDHHC20 PIAS1 TDRD7 C2orf69 SRGAP2C RBM39 GPBP1 RBPJ ETF1 PRKRA DCP1A SCEL ID4 PDIK1L SYNPO2 LRRTM2 PLGLB1 COPS2 EBF2 NEK7 RAB8B PIKFYVE PDCD6IP RGS18 NECAP1 TMTC1 MITF NOTCH1 HMBOX1 GABPA ADRA1A OSBPL9 BMP3 MSRB3 MAP4K4 CNTN4 CCDC50 EPC1 APBB2 IPO7 SNX2 FBXO11 SKIL EEA1 PNPLA8 SP3 PCGF5 THUMPD1 FRYL CREB1 COBLL1 LPCAT2 PDZD2 ZNRF3 PREX2 SMIM20 APH1B SNRK CELF2 AGFG1 SLC25A24 RHOQ PELI1 AGPS CALM1 YTHDF3 EPHA3 DDHD2 CHRAC1 DCK VAMP4 FEM1B PDE12 SH3RF3 CDC37L1 TRGC1 GNAI1 IFNAR1 EWSR1 MAP3K2 RELL1 PCDH17 ATXN1 APLP2 MYOCD TOB1 WBP2 RIMKLB ZNF267 INO80D SYT11 AMD1 BNIP3L RNF138 MIER1 CTTNBP2NL EGFL7 LRP12 RIPK2 CYP2U1 ALDH2 USH2A IPO5 POLR2M SRSF10 KPNA4 RBMS3 TBCEL COMMD8 NHLRC3 STK4 C7orf31 BCAT1 RASSF8 MARC1 NALCN ARPC5 SCAI SKI CHCHD7 SNAP29 FAM126B CNTNAP3B NR3C2 MAPKAP1 DUT SPOPL PURB ENY2 GRPEL1 HPCAL4	down	***
MIR410_3P	0.0018219	0.0198985	0.4550599	-0.2449000	-1.351892	278	SMAD6 DPYSL2 RAPGEF2 PTPRB ZBTB34 TMEM170B CGNL1 BMPR2 NR3C1 MANBA MOB1B NUMB ARHGAP29 UBR3 PLXNA2 KLF10 KLF6 GLS SLC7A11 SRSF2 ANKRD29 BTG3 ATP6V1H SETD3 ROCK2 CCDC82 DGKE TBX4 ZSWIM6 SLC38A11 REST MAFG C9orf72 SMAD7 TBX5 KIAA0408 VEPH1 RUFY3 CNOT6L LIN7A SNX3 UFM1 SCEL PRDM11 DCTN6 ZNF548 UTRN NDNF TMTC1 CPEB4 ETS1 MN1 CNTN4 IPO7 SP3 SDHD COBLL1 RC3H1 LPCAT2 PDZD2 CXCL5 PREX2 LETM2 PBRM1 GLRA3 TEX14 BAZ2B TEC ZCCHC10 CNOT7 COL15A1 MICU3 PDE4B HACE1 FGF2 SLC34A2 RTN4 TIAM1 CXCR4 MFAP5 PSME4 RNF38 C21orf91 RORA NAA15 ZBTB44 STARD13 PSIP1 ACVR1C CHML SVIL	down	*
ZNF274_TARGET_GENES	0.0009046	0.0117379	0.4772708	0.2669231	1.351822	767	SAA2 HNF1A TP63 BBOX1 DDX11 ENTPD2 BDH1 PMFBP1 TFAP2A IGLV1-36 DROSHA FAM177B DDX11-AS1 GBAP1 JPH3 SEMA4B PHF14 RAB3IP LCN2 ASIC1 IQGAP3 SPAG17 ANLN STK31 ASPM PCLO STIL ANKRD24 NUF2 IGLC7 GPI TBX19 ESPL1 E2F3 ANKRD22 PRC1 C19orf57 GON4L MAP2K6 ZFYVE19 KIAA0895 LRRC27 SLC4A8 CYP3A5 SCG5 FAM220A LDHB ZSCAN2 BZW2 ZNF607 NUDT1 MUC6 DLG1 SMARCC1 GFPT1 LINC00665 FANCA CCDC77 CCT5 MYO10 CARD10 TPR RHOBTB3 TRRAP ADAMTS13 PKM WDR73 RIMKLBP2 XXYLT1 LETMD1 BRD9 RAB13 EHHADH ABCB9 MDM2 ZNF48 BRIP1 RABEP2 BLM C2CD3 ALG3 MIPOL1 MYOT FRMD5 CROCC EFCAB6 POLE2 UCK2 PACS1 KIAA0753 RAPGEFL1 ANKRD54 RN7SL812P GIPR PGBD2 PSMB5 MRPL17 KIF2A ANAPC7 NUP205 TRAPPC12 HMGXB3 DIAPH3 ANKRD55 CPXM1 ANXA2R LZTR1 UBN2 ZNF692 NET1 MYO19 ACBD6 ZNF354A FANCG CAPS2 CRLF1 CCNE1 DNAJC17 DLGAP5 SMG5 VPS41 ADNP MLF2 AARSD1 MAN1B1 POLL ADAM28 XYLT2 TRIO OSBPL3 PTGES2 IQCG TRIM37 DUSP12 ENAH CASP7 CENPQ CCDC146 HECTD1 FZR1 MTND5P11 RNF224 YWHAQP6 FHL2 IQCH LIPC SLC1A3 NAIF1 CCT7 RAD50 CENPK PPIEL DGKA PLD1 YLPM1 LINC00467 TTLL3 FBXO22 TCTN1 AP3M2 FAHD1 FIBCD1 PHYKPL CHTF8 C4BPAP1 STAMBP FAM174A RPL7L1 ZNF432 UIMC1 DDX23 LTV1 RTEL1-TNFRSF6B SRSF1 EFHB SDHCP2 RGMB PI4KA ANK3 CHRNA5 ZNF274 MST1P2 C1QTNF3 STRBP DPH5 FARSA ZNF286A DBNL GRHL1 MSS51 GTF3C2 PLSCR2 DTNB SERPIND1 ARRDC1 ARHGAP5 FBN2 MICU1 IKZF4 GNA14 AGBL5 NUBPL ENPP5 GNA12 POLR1B MIR181B2 OFD1P17 TP53 NEIL1 TMEM9B-AS1 FBXO34 ZNF354B SLC38A4 IDUA COPZ2 TTC9C NCAPD3 CLDN10 PPP2R5D RN7SL334P MRPL48 ATF7IP DDB2 NAT10 TTLL5 IMMP2L CYP11A1 KCTD19 SETD5 ANKRD11 ANKRD13D TPM1 MEIS3 TMEM62 INO80B EIF2D VPS26B PLAC8 RPS20P15 VPS18 ARMC2	up	*
MIR548BC	0.0006979	0.0096191	0.4772708	-0.2329051	-1.351745	415	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 PIKFYVE RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 PIAS2 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	**
MIR548A_3P	0.0005412	0.0078474	0.4772708	-0.2319560	-1.351495	413	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP TMED5 MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	**
MIR106A_5P	0.0003494	0.0055575	0.4984931	-0.2233516	-1.348338	554	WEE1 RAB11FIP1 EREG TMEM100 ABHD5 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK SGTB BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 MAPK8 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 TGFB1I1 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	**
GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS	0.0007056	0.0096993	0.4772708	0.2657830	1.347457	777	CCNO STYK1 HKDC1 EPHB3 AK4 CHEK2 BUB1B MYO3B PPIP5K1 NEK2 XYLB CCNB1 FRK POLQ PBK PGM2L1 GUCY2C PRIM2 NMNAT3 TBRG4 IP6K3 STK36 TTK EFNA3 CDK4 BRSK1 STK31 POLE CNTD2 FLAD1 PLK1 EFNA4 AURKB ALDH18A1 CCL8 PAK6 WNK2 CCNB2 PRKCA CCNF PIP4K2C MAP2K6 SGK2 SRPK1 INSRR EPHB1 AGK AK8 TAMM41 NME1 IKBKE POLR3A MELK DLG1 DYRK1B RPAP1 CARD11 POLM MAP3K13 BUB1 AURKA POLA2 ATR POLD2 COASY PRKDC NME9 PKM SBK1 EIF2AK1 PHKG2 PASK TRPT1 NME5 EGFR POLR3C RIPK4 CHEK1 NEK11 EPHA10 PFKP MST1R KHK AKT2 PKMYT1 DDR1 CAD ERCC2 MNAT1 PIGO DYRK2 MARK1 POLN TNIK IKBKB FGGY DCLK1 TTBK1 TERC CMAS FASTK PAK1 LRGUK CDK1 CDK12 EPHA1 POLE2 PI4KAP1 UCK2 MERTK STK32A TNK2 POLR3K MAP3K10 CCNJL ITPKA KSR2 PDK1 NEK5 POLR1C AK7 PRKAA2 UCKL1 MAST1 ACVR1B STK11 TEP1 ULK1 HYKK NMNAT2 POLR2H ANKK1 CCNE1 TRIM24 CDK3 DCAKD NEK10 NADK2 GALK2 MTOR POLL TRIO PIGG MAPK13 EPHB2 TK1 DTYMK PIPSL CSNK1G1 LMTK2 MAPK10 TSSK3 GK5 CDK13 POLD1 TYRO3 POLB CDC7 IP6K2 RAD50 TNK1 FN3KRP DGKA ERBB3 POLR2J GMPPA CKMT2 CDC42BPG SRPK2 NMNAT1 NEK4 POLR2J3 ADCK1 PIP5K1A PFKFB4 POLR2I LRRK1 POLR3E CCNG1 MAB21L1 MUSK PRKD2 STK39 PI4KA STK35 ROS1 PI4KAP2 PMS2P1 ATP6AP1 MAP3K14 CCNA2 ULK4 PRIM1 STK38 CDC42BPA POLR3B CSNK1G2 NME4 PAK4 CTU1 ICK HK2 STK25 MAP3K9 PFKM MARK4 NME7 CDK5 POMK ERBB2 POLR1B PNKP POLR1A GNE GLYCTK GDPGP1 TSSK4 SEPHS1 EPHB4 NPR2 RIPK3 ADCK2 OAS3 PI4KB TK2 BRSK2 MOK ALPK1 MAP3K19 MAP2K2 ERCC3 PRKAG1 ROR2	up	**
PRKDC_TARGET_GENES	0.0010634	0.0133310	0.4550599	0.2666306	1.347169	694	PRR15 SLC2A1-AS1 RUVBL1 CEP89 C1QTNF6 DOC2A DROSHA GBAP1 SEMA4B SLC2A1 PHF14 RGMB-AS1 BRCA1 CREB3L4 CDCA2 ANKZF1 FLAD1 IFT27 CENPA ACOT8 CCNB2 VSTM2L ZNF714 TIGD1 CDC25A PRC1 TDRKH LIPE-AS1 CAND1 SRPK1 KRT15 TRIM45 ZNF726 GOLPH3L RUVBL2 POLR3A CLSTN3 RAB11B-AS1 OSBPL2 CHAF1A SLFN5 HLTF EMC9 LINC00665 TP53BP1 TOP2A IQCD NDUFS2 ZNF587B KLHL25 ZNF174 C14orf93 TPCN1 GNAS-AS1 TMEM45A BRPF3 PASK MCM3 TARS2 CHD6 ZNF443 C7orf50 ORC6 ACTL6A AHCY ANKRD16 SPC24 CNOT3 ZNF587 ERCC2 INCENP EFCAB11 HPS4 FRMD5 CBX5 MRPL37 ANAPC5 PABPN1 CCDC61 RFWD3 CCT3 ANKRD54 ERC2 POLR3K UNG PMEL BPGM C16orf71 KXD1 RALGPS1 PLCG1 DIAPH3 STK11 CHCHD2 SNRNP25 VBP1 ZNF687 UBFD1 CDC23 DLGAP5 DCAKD SPG7 SLC26A2 MTOR TRIM9 FHIT OSBPL3 SLC37A4 HIRA COL5A2 ROGDI COPS7B ZNF417 PLEKHA8 NFATC4 AKAP8L LMTK2 OS9 ANP32E ITFG2 LIN37 ZSWIM3 ZSWIM1 FKBP14 ZNF814 AAMP NAIF1 ZBTB7B CCT7 NR6A1 CCDC137 SEC14L2 GTF3C1 PWWP2A PSMB3 ORMDL2 GBF1 C12orf65 NRXN2 AP3M2 BCL2L1 CDR2 ABCA7 ARVCF KDM4B MRPL28 PRMT1 HIBADH ANKS3 TDP1 ZRANB3 C5orf22 FAM161A ZNF563 LRCH4 ZSCAN32 EXOSC5 CREB3L2 RGMB CCNG1 RSPH4A TCERG1 COPZ1 SPSB3 ZNF837 ZNF519 PMS1 ATP6AP1 TRAPPC12-AS1 CYTH2 PRR11 BBX ZNF66 DOHH ZNF436 NUBP2 ARL17B NBR1 TOMM40L MROH1 BCAS3 ZNF91 TCF3 DNAJC14 EARS2 RHPN1 PGPEP1 MTHFD1 PDZD7 DHRS3 NMT1 TIMM44 PPIA UBE2C RHPN1-AS1 SFXN5 DCAF11 ENO1 ZSCAN20 SLC39A1 PLIN3 COX6B1 THAP3 TTLL5 FAM222B TMEM161A MSANTD4 SETD5 ANKRD11 RPUSD3 COPE DNAL4 HEXIM2 POLRMT PDXP SETD1A ZDHHC13 ZNF678 PPP1R13L WDR63 HRAS RAB40C TRAFD1 TBC1D10B PPP2R5E TRPS1 LCMT1 APBA3 CYB5RL ABHD2 CCDC153 FAM111B NFE2L1 SAFB TMEM9 SLC2A8 ZNF774 TRAF7 GLRX5 ZNF77 CHD8 MPZL1 ZNF682 ARMC6 RPLP0 ABCD3 SHKBP1 AP2A1 RMI1 HNRNPAB PC LRPPRC FMN1 MTHFD2 DHX38 SWSAP1 EVI5L ELMO2 BBS12 DDX49 SCAND2P ZNF691 GLCE TLE1 LINC00654 SNHG10 TANGO2 HNRNPA1 SKA2 ABCB8 WBP1 KHSRP BUB3 GYS1 SLC39A3 CIC TSPAN15 STPG1 NPHP4 GATM ZC2HC1C HNRNPUL1 DAPK3 PET100 BCKDHA ARL17A ENSA ZNF823 KANSL1 ZNF200 YIF1A ZBTB38 PACSIN2 FUT8 TUBGCP6 TMTC4 ZNF431 ANKRD27	up	*
HNF1A_TARGET_GENES	0.0000363	0.0008254	0.5573322	0.2613780	1.347064	1445	MNX1 TSPAN8 ATP6V0A4 DKK1 PKHD1 KIF12 SYT8 PRLR TF CDHR2 HNF1A HKDC1 B3GALT5 BBOX1 NPC1L1 HABP2 ABCC2 SLCO5A1 FGA C1GALT1 HOXB-AS3 FOXA3 CDH17 KRT5 LAD1 RUVBL1 DNAH2 BDH1 BHMT SLC13A3 DEPTOR CHEK2 SPINK13 CP NUP107 SLFN13 ANKFN1 NEK2 BAIAP2L2 UGT8 SOX2 FRK APOLD1 C17orf75 ACMSD GCNT3 LINC00941 RAB3IP TSFM TTC39A TBRG4 TMEM86B CDCA7 GAL3ST1 SIX4 IRS1 TUBB2B LCN2 XKR4 GINS1 CDCA2 BCL2L15 SLC27A2 CATSPERB ABCA12 STK31 PMS2CL NAALADL2 IGLV3-9 SPP1 TTC26 NUF2 KCNQ5 PROC MST1L ALDH18A1 ECT2 CUEDC1 RBBP8 ARHGAP33 TYMS SP5 SLC4A4 DNAH3 FERMT1 GRB7 EFNA5 SLC7A9 PAH ACY1 TMCC1 HNF4G MAP2K6 ZFYVE19 SGK2 LIME1 VILL DZANK1 COX11 LRRC31 SPDL1 GPX2 SCG5 NME1 SIPA1L3 TOP3B RANBP1 MANSC1 POLR3A CCDC150 C1orf220 NEURL2 BTRC ZNF572 CUL9 ALG1L BICD1 MRPL15 TRIM29 KIF3B BUB1 IDO1 BPHL APOL1 AGT THBS4 C1orf226 KLHDC7A SFI1 HAVCR1 ZNF174 RSRC1 COASY MPHOSPH9 CPD C1RL RRM2 ANKRD52 WDHD1 RNF43 IL20RB ANKDD1B ZNHIT6 DCDC2 MCM3 WDR66 LINC00511 WDR72 CCDC58 TARS2 ANG MDK CHD6 PSMG4 ZNF443 RIPK4 ZNHIT1 PDZK1IP1 ARHGEF38 TRMT61B PSMD4 THAP10 KHK TBC1D8 TRMT2A MRPS11 DNAH11 C22orf46 FDXR GRHL2 COMMD4 SYMPK NAA40 C2CD3 IDH2 ALDOA MNAT1 STXBP4 SPRY1 PARD3 SLC39A5 ENTPD5 PPP1R37 DHRS13 PES1 GCKR MIPOL1 FGGY CKS1B EXOC3L4 RASSF6 ISOC2 NSF FRMPD2 PLOD2 ANAPC5 OSMR CDK12 LRP2 SSBP1 STON2 DIDO1 ZNF652 CCT3 EEPD1 GMNN DMGDH TBX15 STX18 MKRN1 DGAT2 WDR31 SLC25A13 PMEL DHX33 ENPP3 FAM186A KRBA1 ZNF775 TMEM79 MECR POC1B LINC00649 SEMA3A SNRPE HMGXB3 CCDC57 PBLD ZNF827 FAM102A WDR24 CPXM1 ZNF500 IFT52 UNC45A EIF6 LGR5 GOLGA3 ACBD6 RPS18P9 ELMOD3 G6PC3 PLEKHM1 DNAJC17 EDEM3 VWA5B2 SMG5 SPG7 COA3 VPS41 GALK2 ADAM28 UROS LLGL2 S100A16 DHODH PLEKHG3 PIGG GPRC5C SLC37A4 ASGR2 IQCG RGS22 CCDC130 ENAH ZNF761 MLEC MSI2 CSNK1G1 GAS2 SLC22A5 CCDC146 MAPK10 USP43 STX18-AS1 LAMTOR2 MMP7 DNAJC11 ZNF768 SLC4A2 DNMBP SEMA4G ACSL6 C12orf73 TAS2R19 LIPC PRRG2 OLFML2B ATAD5 ENC1 AAMP CNDP2 IP6K2 DHTKD1 ETV4 BAZ2A SASS6 KLC4 SH2B1 TADA3 UBQLN4 EFCAB7 LSG1 CKAP5 CPSF4 COG1 VPS25 RPRD1B CENPM PLD1 AHCYL1 FTCD SIRT4 MAN2A1 LIPG MRPS23 ZNF76 PPP6R1 ABCC3 IGFL2 KRT8 GID8 RAI14 CENPT NSUN6 DHX8 NOSIP HIBADH	up	***
GO_POSITIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS	0.0030634	0.0296086	0.4317077	-0.2371925	-1.346440	311	GPD1 TRIM71 HMOX1 ABHD5 IL1B ATXN3 RDX PCSK9 ECSCR CAV1 PAFAH1B2 TRIB1 RCHY1 EDEM1 FBXO7 BTG2 RNF144B FAM122A ADRB2 NFE2L2 ZYG11B FBXL5 ROCK2 RAB12 FOXO1 MEFV RNFT1 ROCK1 DAB2 CEBPA SOCS5 EPM2A UBQLN1 ATG7 C9orf72 RNF139 SMAD7 CPT1A PINK1 HTT CNOT6L PIAS1 IL6 PSEN1 NKD2 HSPA1B PLK3 RC3H1 UVRAG RALB SNX9 GRSF1 PNPLA2 YTHDF3 FOXO3 HNRNPD TFEB SMCR8 METTL14 YTHDF2 CBFA2T3 ZC3H12D IRS2 CNOT7 CD81 BAG6 TOB1 BNIP3L SESN1 PIP4K2A HSP90AA1 CALCOCO2 RIPK2 ARIH1 ULK2 DAPK1 CTSC PTEN ITCH LDLR CNOT8 ZFAND2A PUM1 VPS13D KAT5 HERPUD1	down	*
PUJANA_BRCA1_PCC_NETWORK	0.0000539	0.0011483	0.5573322	0.2616180	1.345884	1376	SIM2 RIBC2 TRIP13 HNF1A B3GALT5 DDX11 FOXM1 MDM1 RUVBL1 CDC45 FANCI ZNF273 TROAP CHEK2 BUB1B NEK2 CCNB1 CENPF IGF2BP3 TIMELESS NPAS1 COA1 GGCT TTF2 NDC80 TSFM TTC39A BRCA1 BET1 ECE2 TTK GINS1 EFNA3 CDK4 GTSE1 KIF14 GMPS POLE STIL EIF2B5 NDUFS6 TOMM34 PLK1 AURKB CENPA PTTG1 ESPL1 RGS6 CDC6 B4GALNT1 TPX2 E2F3 GAPDH TFDP2 NNT CCNB2 NBR2 RBBP8 MCM4 MCM2 TYMS XPNPEP1 CDC25A MYBL2 XRCC2 ORC1 CCNF EIF3B CCT6A LIG3 SRPK1 SHMT2 XPOT NCAPD2 ZWINT CDT1 COX11 AP1G2 PVT1 CCT2 ASTN2 LSM5 NME1 LDHB IKBKE TOP3B RANBP1 RUVBL2 CASP2 MELK HMMR EXO1 NUDT1 SMARCC1 KIF23 CHAF1A LAMC2 MKI67 CUL9 HLTF PCCB KNTC1 PAFAH1B3 BUB1 EEF1E1 TOP2A IDO1 CCT5 AURKA SPTB NUP155 CBX3 PMS2P4 POLA2 ATR POLD2 SFI1 LARS2 TPR KIF2C MCM7 CD2AP COASY MPHOSPH9 RRM2 PRKDC WDHD1 RAD54L ERAL1 MRPL3 KIF11 MCM3 CHAF1B LMNB1 CDC25C MCCC2 AIMP2 B3GNTL1 RNFT2 LIG1 POLR3C TOPBP1 CHEK1 DNAJC9 ACTL6A MAD2L1 AHCY FBL RAD51AP1 MDM2 PKMYT1 CAD ETFA BLM CNOT3 GLE1 MNAT1 MYO1A PARP1 PES1 GEMIN4 THOP1 CKS1B EFCAB11 CDKN2C MEA1 PPIL2 TMEM106C CBX5 ANAPC5 IQCB1 CDK1 PABPN1 HDGF SSBP1 POLE2 SNX4 DIDO1 UCK2 CCT3 ATIC GTF2E1 RBCK1 NPM3 E2F1 UNG TCF20 TRAP1 SNAPC1 DNA2 SEC61G KIF2A ANKRD26 PDK1 FEN1 EZH2 NUP205 POLR1C SPAG5 KXD1 TAF6 LRRC42 PLCG1 OARD1 TTI1 SNRPE NOP2 PSMC4 RECQL4 ITGA2B FGFR1OP PA2G4 RNASEH2A DNAJC7 KPNB1 POLR2H TBX1 DNMT1 VBP1 PELP1 UBFD1 TELO2 ILF2 CCNE1 NPHP1 TRIM24 CDC23 GNPAT DLGAP5 PSMA5 ADNP MTOR GSS SNRPA LMNB2 MBD4 GALNS PSME2 OSBPL3 HIRA HMGN3 ZNF37A SSRP1 DPH2 TK1 DTYMK CASP7 HDAC1 ANP32E IFNAR2 ITFG2 TCEA1 KIF20B DAP3 IGHM NOC2L ASNS TM9SF4 SAP30 CDK13 POLB ELAC2 CCT7 CDC7 TNK1 P4HA1 EP400 PFAS CKAP5 CPSF4 KCNB1 CDC20 STOML2 IARS2 PPP1R8 HMGA1 RRP9 CLASRP ACLY RPA1 PPP6R1 POLR2J ZNF202 SRRT CLINT1 PEX5 MCM6 COMP KIF21B TBCA MED24 PRMT1 UTP20 MCM5 SNRPD1 LSM7 TFAP4 EIF3D SRSF1 AATF KATNB1 DOLPP1 RCC1 CCNG1 SLC1A5 LSM4 PSMB4 TXNL4A EIF3K U2AF2 TSR1 TCERG1 ALG8 NUP62 FARSA PYCR1 PMS2P1 PMS1 MSH2 CCNA2 SMARCA4 RBM42 PRIM1 ZNF195 GTF3C2 VDAC1 SNRPD2 RFC5 CSNK1G2 PDAP1 ABCF2 ACKR2 WDR77 PRPF31 HK2 BMS1 RAD51 ST20 ARHGAP11A EYA4 SRP9 TARBP1 PAXIP1 SNRNP200 UBAP2L ZNF131 CIAPIN1 SMC2 PARG GOSR1 XPC CENPE ABO TCF3 PFDN4 DDX52 POP4 SMPD4 TP53 NMT1 PAICS TIMM44 CHERP APEX1 MRPS27 SNRPC PPIA TBL3 UBE2C PNN TAF4 GPN1 NELFA UBTF PWP1 RIMS1 GP1BA ENO1 NUP210 BFSP2 RAD1 SMARCB1 DDB2 RRS1 PLIN3 NUP93 ZNF337 COX17 SART3 TRAPPC6A IFI16 TIPRL ERCC3 NCAPH GEMIN2 CYB5B PARP2 LYPLA1 GRIP2 CLNS1A CD38	up	**
GO_NEGATIVE_REGULATION_OF_CYTOKINE_PRODUCTION	0.0052163	0.0441398	0.4070179	-0.2476828	-1.345557	215	FFAR4 ACP5 HMOX1 IL1RL1 GAS6 SLC11A1 IL23A APOD ANXA1 MIR146A ATP2B1 CARD16 CD33 RNF125 GATA3 SIRPA RGCC SRGN IL10 ARRB1 MEFV KLF4 THBS1 SOCS5 NFKB1 PTPRC AXL TLR4 MIR24-2 SFTPD SMAD7 INHBA TGFB2 NCKAP1L IL6 CARD8 TYROBP PTGER4 CD83 REL TBX21 TIGIT CD34 KLF2 WNT11 TGFB1 SERPINB1 LRRC32 NPTN GATA6 GPR18 TSPO SYT11 ARRB2 NLRP3 HAVCR2 EPHA2 FGFR1 ITCH BANK1 KAT5 C5AR2 CX3CR1 TREM2 ZFP36 NDFIP1 MUL1 SSC5D HMGB1 NMI	down	*
ZC3H11A_TARGET_GENES	0.0012679	0.0152628	0.4550599	0.2653620	1.345022	753	MIR1205 FBXW8 ZDHHC4 ZMYND8 PDCD6 NUP107 ABCA17P C17orf75 NPAS1 DDIT4 THEM4 C6orf141 ASIC1 LRRC37A3 UBE2Z NOL12 ILDR1 TTC26 DGCR8 NUF2 AURKB TIGD1 XRCC2 CDK5RAP3 PVT1 AGK INTS1 LSM5 NME1 TOP3B CASP2 TMEM41A ZNF74 NLE1 XPNPEP3 ZNF391 BBS1 KIF15 KNTC1 IGF2BP2 RFXANK ITGB4 SAE1 GTPBP3 E2F2 LPIN3 RBM28 CCDC58 TARS2 YEATS2 SLC37A3 EME2 HEBP2 ZNF786 TRMT61B GAS8 TMEM63A B4GALT7 GEMIN7 DDR1 EEFSEC SPAG8 ALDOA PPP1R37 DHRS13 PARP1 GEMIN4 RNF216 C9orf163 PPIL2 DDX51 MB SUPT5H CBX5 ASF1B PAK1 ANAPC5 SSBP1 EXOSC2 STX18 VPS28 MCAT WDR31 FAM98C DHX33 ENPP3 PSMG3 TNRC18 HMGXB3 CCDC57 CENPP WDR24 KPNB1 GOLGA3 ZSCAN9 EXOC7 DTX2 NADK2 GALK2 TRMU ADNP JOSD2 TRADD MRPS34 CCDC151 KIF22 PIGG SLC37A4 HIRA USB1 TIGD6 COPS7B ARL6IP4 JMJD4 MLEC GEMIN5 STX18-AS1 LRWD1 ZNF768 IGLV1-47 GFM2 TSEN54 KDM3B FAM207A C12orf73 GNAZ PRRG2 ZBTB45 CLTB DNAJB13 DHTKD1 ETV4 RNF187 FAM71E1 SH2B1 EP400 EFCAB7 PFAS CPSF4 VPS25 STOML2 KIAA0100 CA11 HMGA1 DUS1L FBXO22 BEND6 SLFN12 ALKBH4 ZNF76 PPP6R1 NOL6 MADCAM1 SRRT MRPL24 DHX8 NOSIP MCM5 TMEM147 NOC4L SNRPD1 SIRT5 SNAP47 SLC35A3 CACNB3 RTEL1-TNFRSF6B NFE2 STMN3 NDUFS7 YIPF2 WDR45B IGHMBP2 PI4KA DDX55 MST1P2 DUS2 ZNF580 NME1-NME2 PRPF18 AGMAT TSPAN10 CYTH2 BANF1 RTEL1 POLR3B MRPL55 CLUAP1 ACSF3 CCDC88B LPGAT1 BMS1 TTC1 TRIP4 SEC13 CHMP1A PFKM MARK4 GTF3C5 MRPL21 SNRNP200 VPS9D1 CHMP2A TMEM101 AURKAIP1 MAPK8IP3 ADRM1 ZNF205 GGCX ZNF341 FBXO34 PPIA TBL3 PIGL DCDC1 UBTF MRPL20 TMEM98 SART1 SPATA20 ATF7IP ZER1 CLASP1 TRUB2 HEMK1 TRPC4AP SNAP25 SLC33A1 SPATA33 KIAA0586 INO80B ZNF554 EIF2D SHROOM1 ABLIM3 MAN2C1 MED15 RAB40C NELFB AKAP9 COMTD1 TMEM259 RPL36 NOXA1 ZC3HC1 ZNF276 SDHAF1 TNPO3 OPA1 PANK4 SAFB LTK NSL1 EDC4 MCEE TYK2 TEFM GAK SAFB2 SLC20A2 NUDT8 SLC27A5 MAP3K5 MBD6 DGCR2 RBM8A GGA3 KEAP1 TXN2 OLFM2	up	*
MIR513A_5P	0.0022144	0.0231784	0.4317077	-0.2354083	-1.344457	316	SEMA6A ABHD5 PRKG2 SNX10 DPYSL2 ZBTB34 TMEM170B CD44 ST3GAL6 KIAA1109 GTF2I HMGCR DYRK1A RGPD5 OTUD4 ADAM17 LATS2 MTF1 BTG2 FZD4 KLF6 SLC7A11 ABHD6 ASH2L GATA3 SFRP1 RAB14 NODAL SLC7A2 TLE4 CCDC82 PPP6R3 LIN7C ZCCHC24 PDE8A MGAT4A NPAS3 ARHGEF26 PTGER3 CCSER2 RNF139 FAM76B SNN BTG1 SLC25A25 ID4 FAM189A1 DNAJC27 EBF2 MAGI2 NECAP1 C2CD2 RCAN1 DDX5 GRB2 RC3H1 MORC3 SNRK CDK14 AGFG1 GRSF1 AGPS NIPAL4 YTHDF3 SLC35F1 PKIA AKIRIN2 STRN PHF3 PDS5B SBF2 APLP2 ANKRD12 NPTN KAT2B ATAD2B INO80D PET117 UBE2D1 VSIG10 RASSF8 MARC1 TLK2 PRKG1 MMD SAMSN1 NABP1 SMAD4 HSDL1 SPATA13 UBE2V1 ACVR1C TSTD3 TREML1 ZNF800 ADAMTSL1 LIN52	down	*
GO_MULTI_ORGANISM_REPRODUCTIVE_PROCESS	0.0012836	0.0154193	0.4550599	0.2667940	1.343363	664	TSPAN8 SYT8 PRLR TRIP13 TP63 ABCC2 SPATA24 SPATA25 MYCBPAP FOXA3 PPP1R1B RUVBL1 PMFBP1 SPINK13 CCNB1 WFDC2 DPY19L2P1 SLC2A1 CLGN GAL3ST1 CREB3L4 ZP3 TTK RACGAP1 CATSPERB SLC26A8 SPP1 ASPM TTC26 PLK1 IFT27 PTTG1 B4GALNT1 SOX9 FIGNL1 STC2 CYP27B1 UMPS NOX5 APOL2 SPINK1 CIB1 TDRKH MCM8 SRPK1 CCT2 RSPH1 ITGA2 ZSCAN2 OSBP2 SOX30 RPL39L SPAG16 DPY19L2P2 FOXJ1 TSGA10 PAFAH1B3 FANCA TOP2A IDO1 CCT5 AURKA AGT REC8 ODF2 SYCP2 POC1A IL12B DPCD SPEF2 SGPL1 PCDHGA4 NSUN2 HOOK1 FANCD2 HORMAD1 CDC25C ANG MDK NME5 OAZ3 CGB7 HSF2BP MST1R OXTR BRIP1 DDR1 CAD GNPDA1 SPAG8 PTGDR2 CCDC136 ALDOA MEA1 IGFBP5 ASF1B LRGUK CDK1 MERTK PICK1 CCT3 GOT2 SUN1 E2F1 SPATA9 ZNF541 GJB3 SPAG6 ACSBG2 METTL3 USP42 ACVR1B STK11 LGR5 GOLGA3 FANCG CATSPERG PABPC1L CATSPER3 NPHP1 VIPAS39 GGT2 TSNAXIP1 MTOR CTSV MNS1 ADAM28 DHODH IQCG MORN2 UBE2Q1 PCSK4 GAS2 TSSK3 SPAG1 MMP7 TEKT3 SPA17 PRMT7 SPATA32 SLC4A2 CHD5 THRB ESR1 TYRO3 CCT7 NR6A1 KDM3A EPN1 PTN MEI1 ROPN1B AAAS BCL2L1 CATSPER2 BAD TFCP2L1 DNMT3A CELF4 RAI14 GGT3P DPY19L2 PYGO2 PKDREJ PTHLH GGT5 ETV6 PHC2 SH3PXD2B PATZ1 STRBP NUP62 SPAG4 ROS1 MSH4 CATSPER1 MSH2 ADM	up	*
WEI_MYCN_TARGETS_WITH_E_BOX	0.0011952	0.0146039	0.4550599	0.2657154	1.343102	698	ATP10B TRIP13 FGA HELLS NXPH4 RUVBL1 MCM10 S100A2 PDCD6 BUB1B NUP107 PPFIA4 PDCD2L GGCT MND1 CHST4 PRIM2 DEPDC1 DEPDC1B EFNA3 PRR15L ANLN NDUFS6 FLAD1 TOMM34 AURKB CENPA CDC6 E2F3 UHRF1 MCM4 RAD54B CDC25A UMPS CA12 EIF3B CCT6A MCM8 MIS18A MAP2K6 SRPK1 P2RX2 MRPS35 COQ3 CCT2 SPDL1 HMMR CISD1 DCBLD2 F2RL1 MRPL15 BUB1 CCDC77 EEF1E1 PUS7 NUP155 TMEM177 GTPBP3 MSX1 RRM2 CDCA5 NSUN2 AKAP1 MRPL27 CCDC58 L3HYPDH FAM162A SLC35G2 CHEK1 ORC6 MAD2L1 SLC25A39 DCTPP1 TIMM50 BACE2 DSCC1 GNPDA1 BLM MRPS30 PHB SYMPK ALDOA SLC25A10 CCDC138 SKP2 PARP1 THOP1 MRPL36 KIAA0556 ANAPC5 PPM1E CDK1 PABPN1 POLE2 EXOSC2 UCK2 RFWD3 BIRC5 C1orf112 GMNN OAT POLR3K DHX37 STEAP1 MRPS2 DHX33 SSX2IP DYNLL2 MRPS12 NLN NOP2 ACVR1B LAPTM4B PA2G4 KPNB1 ANKRD39 NMNAT2 DNMT1 CCNE1 YDJC PSMA5 PUS1 FNDC4 ZNF468 C1orf131 MLEC GEMIN5 MRPL4 ANP32E SAP30 PSMD2 CCT7 CDC7 YARS2 CCDC137 CENPK GEMIN6 CENPV LSG1 GOLM1 PGBD5 CHCHD1 FBXO22 RRP9 POP7 FAHD1 MRPS23 ACLY MRPL41 LRRC15 PRMT1 XRCC4 SNRPD1 MALSU1 HAUS6 RABEPK C1orf109 RCC1 LSM4 CHRNA5 ATAD2 GOSR2 GTPBP10 CKAP4 NME1-NME2 CAPN15 MRPL14 MSH2 ME1 SMARCA4 CANT1 POLR3B ABCF2 WDR4 WDR77 HK2 LPGAT1 HLCS FARSB ZWILCH ZMYND19 LLPH SNRNP70 CTTN UNKL UBAP2L SLC12A2 SMC2 POLR1B EIF4G1 POP4 NMT1 SRPRB BCAN PAICS HGS SIGMAR1 FBXO45 SFXN4 RFT1 PWP1 ENO1	up	*
GO_CELL_JUNCTION_ORGANIZATION	0.0035046	0.0329773	0.4317077	-0.2457985	-1.342536	250	LIMS2 ACVRL1 TEK ACE DLC1 PECAM1 IL1B WNT4 RDX RAPGEF2 RAMP2 CDH5 CAV1 CORO1C CDH13 ESAM CDC42 CD9 EPB41L3 HEG1 RHOA NUMB APOD RAP1A ITGA5 JAM3 TNS1 SFRP1 GPBAR1 ROCK2 SNAI1 DUSP3 SORBS1 PTPRO LIMS1 ROCK1 VASP TJP1 THBS1 CLDN5 CADM1 SMAD7 PEAK1 ADD1 MAPRE2 TGFB2 SRF MYO1C FAM107A RAB8B PDCD6IP MAP4K4 RAPGEF1 FERMT2 PRKACA PPM1F CD151 GJA4 WNT11 FLNC EPHA3 TGFB1 PARD6A STRN TESK2 CNTNAP1 CLASP2 ACTN2 MACF1	down	*
MIR548H_3P_MIR548Z	0.0003589	0.0056808	0.4984931	-0.2253060	-1.341944	518	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 CPEB4 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA	down	**
MIR545_5P	0.0034117	0.0322721	0.4317077	-0.2412163	-1.339915	266	RAB11FIP1 SC5D SLC12A6 GAPT BDNF BACH1 QKI ZCCHC2 VAMP2 ARL8B ATF7IP2 ASAP1 LATS2 ENTPD1 RAP1A SDE2 SLAIN2 FOXJ3 CD58 PTPN21 AHNAK TSPAN12 PKD1L1 YBX3 RNFT1 ROCK1 ERP44 CCND2 CCSER2 ELK3 TBX5 PRICKLE2 BCLAF1 KPNA3 AKIRIN1 PDK4 UFM1 MYLIP RYBP RAB8B PPA2 GABPA APBB2 DUSP8 RCAN1 DDX5 PCGF5 IDS MORC3 AP3B1 CELF2 MAPK8 PHF3 PDS5B TSC22D1 CSDE1 TOB1 HINT3 GATA6 NBEAL1 PLEKHO2 MBNL1 ATAD2B BNIP3L B3GALNT1 UBE2D1 SSH2 C7orf31 LYST MMD PAIP2 SAMSN1 DOCK4 NAA15 SFPQ CNOT8 BMI1 ACVR1C CFL2 MAPK1 MAMDC2 ANKS1A ATP1B1 VPS36 SGIP1 CAPZA1 SGPP1 STX16 ARHGEF12 PAXBP1 DR1 MAP3K1 RNF111 WDR26 SETD2 KATNAL1	down	*
MIR548AC	0.0004921	0.0072548	0.4772708	-0.2244333	-1.339873	516	EREG SIDT2 SASH1 STAC TRHDE TBX3 ZC3H12C CPEB2 LRRC8C EMP2 MBOAT2 PID1 RUNDC3B ZBTB34 TMEM170B DDX6 YPEL5 DYRK1A MOB1B ARHGAP29 SEMA6D STARD4 B3GNT5 TM2D3 ZBTB21 CAMTA1 ZBTB8A RB1 TCF7L2 MCL1 SETD3 FLI1 ZMIZ1 HIF3A LIN7C TCP11L2 YBX3 LEPROTL1 KLF11 ZFAND5 SOCS5 FAM49B ERP44 ATL3 DOCK9 NPAS3 CDS2 CCND2 TAF9 ZMPSTE24 KIAA0408 PDE1C USP16 FAM76B TLL1 CMTM6 CNOT6L STK24 SPIN1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 IL6 YBX1 COPS2 UTRN C2CD2 MITF ARL6IP6 GABPA KCTD12 FOXN2 EPC1 MCM9 FYTTD1 BAG5 SKIL TTC14 PIK3R1 DDX5 PI4K2B IDS RC3H1 FSD1L ATP13A3 NOL7 YWHAZ LETM2 SNRK CDK14 TMEM128 PELI1 CDK17 YTHDF3 MAPK8 ING3 AZIN1 KIAA0232 ABHD13 CNOT7 PIM1 CCDC68 CRY1 INO80D DOCK6 HELZ RBL2 ARAP2 NEK1 FKBP1A ITPRIPL2 ZNF583 UBE2D1 TDRP MEX3C NUP98 ZDHHC21 CREBBP GRIN3A SOAT1 KPNA4 RBMS3 PLGRKT HNRNPC TTC28 DOCK10 RNF38 SCAI SKI FAM126B CAMSAP2 RORA	down	**
MIR520A_3P	0.0021939	0.0230394	0.4317077	-0.2427409	-1.338875	288	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 SLC16A10 PLAG1 ARHGEF17 CFL2	down	*
MIR548E_3P	0.0006415	0.0090262	0.4772708	-0.2297716	-1.338788	414	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 VASP MYO1B GPR85 HNRNPUL2 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 SMNDC1 CNOT6L PIAS1 SERTAD2 VPS37A DNAJC27 DDHD1 MED28 EBF2 NEK7 PIKFYVE RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 SLC25A24 CTTNBP2 CALM1 FOXO3 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A DKK3 ATF2 CDC42BPB ADAMTSL3 PIK3CG SRSF11 XRN2 SV2B TRPM7 SGIP1 GPR137B WDR47 PDE7B GABPB1	down	**
MIR520D_3P	0.0024286	0.0248712	0.4317077	-0.2410060	-1.338453	287	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 PLAG1 ARHGEF17 CFL2	down	*
MODULE_38	0.0008076	0.0107562	0.4772708	-0.2303929	-1.338058	383	TNR EPAS1 HMOX1 PECAM1 GATA2 CLEC3B EMP2 CYP4B1 RAMP2 CDH5 ENG LMO2 CAV1 CITED2 ADRA1D ALAS1 TGFBR3 FUCA1 HSPG2 FGR HEG1 APOD ANXA1 TBX2 BMP1 PLXNA2 ITGA5 ACOT2 ANPEP RNASE1 SERPINB9 LAIR1 GATA3 GRN MTHFR SLC5A2 RHOB MAP2K3 CFD PTPRO GPA33 KIAA0513 RUNX1T1 DAB2 SLC7A8 CLDN5 GRK5 LAPTM5 CDKN1A ATF3 HOPX IGFBP2 M6PR PER1 WFS1 ACTG2 VAMP5 MYH11 HES1 MAFF CRIM1 PTH1R VWF PROCR EMP3 FAM107A FLT1 SLCO2B1 LAMB2 CYB5R1 ETV3 RAB31 LTBP2 DDX17 PLK3 JUNB PPP1R15A COBLL1 MFAP4 FSTL3 CLN3 CD34 CD151 GJA4 FOSB SMPDL3B TIMP2 TGFB1 SFTPC DUSP5 MMP15 LRRC32 NFYC PIM1 COL15A1 FCGRT PLEKHO2 LTBP1 ETS2 SOD3 HSPA2 GPX3	down	*
MIR17_5P	0.0005623	0.0080899	0.4772708	-0.2207958	-1.337216	539	WEE1 RAB11FIP1 EREG TMEM100 ABHD5 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK SGTB BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 MAPK8 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 TGFB1I1 CNOT7 MAP3K2 ATXN1 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	**
PEREZ_TP63_TARGETS	0.0057710	0.0475311	0.4070179	-0.2396564	-1.336972	285	SMAD6 LIMS2 RAB11FIP1 CLIC3 IL17RB SASH1 FOXF1 CD101 DLC1 BMP2 SHANK3 LMO2 CGNL1 SUSD2 SLC39A8 IL1RN EPB41L3 SEMA6D TACC1 KCNK3 HSPB1 LUZP1 PTX3 ABHD6 RGCC PPP1R13B ITSN2 RHOB CSRNP1 ARRB1 NRARP ZSWIM6 ZCCHC24 MAP1LC3B GRK5 SHC4 ID2 LBH SMAD7 PLCD1 FOXN3 MYLIP RBP7 FRY ID4 SOCS3 ZNF548 AQP3 NXF1 SLC35E4 HSPA1B ATP11A RCAN1 HUNK FRYL FAM43A RTN4R ZNRF3 GFPT2 LGALS2 CASZ1 PALMD CELF2 ACSL1 RUNX3 FOXO3 EPPK1 TSHZ3	down	*
GO_REGULATION_OF_CELL_MORPHOGENESIS	0.0010145	0.0128472	0.4550599	-0.2303510	-1.336922	415	TNR LIMS2 DAB1 SEMA6B SEMA3G SEMA6A WTIP DLC1 FGD5 P2RY1 RDX DPYSL2 RAPGEF2 TRPV2 BDNF FYN SHANK3 CD44 CORO1C MYADM NEDD4L BAIAP2 BMPR2 CDC42EP2 CDC42 NEDD9 EPB41L3 FGR RHOA ZEB2 SEMA6D ANXA1 SEMA3B TTL HECW2 PLXNA2 FZD4 PPP3CA ZMYM6 PLXNA4 ISLR2 NDEL1 CRK WNT3A ITSN2 ATP10A RHOB LRP4 AGO4 PTPRO LIMS1 ZSWIM6 TRIM46 PARVB MPL FMNL3 CCL3 ARC SS18L2 WASF3 ZMPSTE24 PAFAH1B1 RUFY3 ACTR2 HEXB HCK SRF KANK1 FMNL2 PSEN1 RHOBTB2 LIMD1 RAC2 RHOG RHOJ PALM FERMT2 SKIL IFRD1 RTN4R TRAK2 PALMD RHOQ EPB42 ZRANB1 HECW1 GNA13 MACF1 PLAA ADAM10 IST1 UNC13D ICAM1 PDLIM5 ARPC2 WDR1 SEMA4A RTN4 CDC42EP3 TIAM1 CXCR4 EPHA4 ARHGAP18 BRWD1 RND1 ULK2 PARVA SIN3A RET KIT PTEN	down	*
MIR664B_3P	0.0010727	0.0134212	0.4550599	-0.2296129	-1.334770	404	GCOM1 MBOAT2 ZBTB34 MMRN1 MED4 CLEC12B LONRF1 NEDD4L QKI NTM KCNN3 DSCAML1 MOB1B TMX4 DNAJB14 ZBTB4 WWC2 NCEH1 B3GNT5 UBL3 SLC25A17 ARSB RAP1A SWT1 BZW1 SERINC1 SPIRE1 GLS CAV2 CAMTA1 SLC7A11 GLDN TBC1D9 ARRB1 DGKE SORBS1 LIMS1 KLF9 ANKRD10 KLF7 MYRIP SEC24B ERP44 LAPTM5 NPAS3 AQP4 PTGER3 CPT1A PTCHD4 GNAQ PRICKLE2 NUS1 TBC1D4 FAM76B NCKAP5 IKZF5 CLIC5 GPBP1 PDIK1L LRRTM2 PHACTR2 PLEKHA3 OXNAD1 GABPA APBB2 IPO7 SKIL PNPLA8 PIK3R1 IRF8 FRYL COBLL1 HSD17B12 SH2D4B ZNRF3 UVRAG OGFRL1 DENND4A AGFG1 RHOQ CALM1 YTHDF3 USP7 PSMD12 HSF5	down	*
GO_DIVALENT_INORGANIC_CATION_HOMEOSTASIS	0.0017994	0.0197343	0.4550599	-0.2304112	-1.333668	394	SLC24A4 HCRTR1 GPR17 RAMP3 CD52 SWAP70 MCOLN1 EDNRB CD55 GATA2 F2RL3 SNX10 P2RY1 GPR65 CDH5 KL TRPC3 FYN JPH4 CCRL2 CAV1 ADRA1D GTF2I SLC39A8 ADCYAP1R1 TBXA2R C5AR1 S1PR1 SLC11A1 CD36 JPH2 ATP2B1 KCNK3 ANXA5 MS4A1 PDE4D TMEM38B GPR4 SYNPO PTGIR RMDN3 CCL3 PTPRC PTGER3 RAP1GDS1 WFS1 HTT GPR157 UBASH3B CALM2 PLCD1 PTH1R HEXB KCNA5 S1PR4 SLC8A1 PDE6A PSEN1 PDE6B CNNM2 ADRA1A JPH1 GSTO1 PTGER4 CCR7 ACKR3 PRKCE PTGER2 GRIA1 ATP13A3 PRKACA SLC10A7 CLN3 PLCG2 CALM1 PKD2 SYPL2 CCR4 FPR2 MCUR1 SLC24A1 SLC8A3 CCR1 NPTN GNA13 GPR18 CALB1 CCR6 FGF2 ABL2 FKBP1A SLC24A5 TPT1 CXCR4 CCR9 MT1M BOK CD19 EDN1 MCOLN2 P2RX1 MT2A LPAR6 ATF4 CYBA HERPUD1 C5AR2 FKBP1B CX3CR1 S100A8 FPR1 ATP1B1 PIK3CG MT1E CALR BDKRB2 FPR3 TRPM7 WNT5A PLN GPR55 HMGB1	down	*
CBX5_TARGET_GENES	0.0035810	0.0334872	0.4317077	0.2659843	1.333032	601	PDE11A PCSK6 HNF1A MYEOV MROH3P C1GALT1 KRT5 LAD1 BDH1 GPT2 PMFBP1 EPN3 SLC13A3 NGEF SYNPR PRSS2 ZNF280B COA1 PRIM2 ZNF138 FABP6 LRRC37A3 FA2H NPAS2 POLE ENAM SEC14L5 WDR70 CUEDC1 WNK2 TMCC1-AS1 RUNDC3A PDE9A LRRC27 DNAH14 AOC1 AGK WDR90 MICALL2 CLPTM1L TMEM41A MUC6 ZNF391 OSBPL2 FSIP2 EXOC4 GPER1 ZNF766 ITGB4 MAD1L1 MRPL3 ENTPD6 ANKMY1 TARS2 B3GNTL1 PKMYT1 CAD PTGFRN ZNF605 FADS2 NIPAL1 R3HDM2 OSBPL7 BTBD2 DCLK1 EXOC3L4 PPIL2 LAMB4 DDX51 PAK1 KRT18 SLC39A11 OSMR ARHGAP39 CD300A PACS1 PHF12 GOT2 SUN1 GIPR PGBD2 SYN3 ENPP3 KRBA1 PSMG3 PLCG1 NAPEPLD LZTR1 CHCHD2 ZNF687 CAPS2 YDJC ADNP TACC3 ATP9A MAN1B1 XYLT2 ARHGAP32 HIRA MAPK13 TRIM37 TMTC2 JMJD4 HECTD1 STEAP1B TCEA1 DLK2 GUSBP1 GFM2 EPB41L4B NRF1 FAM207A ITGB2-AS1 MT-TH CCDC159 EFCAB8 OLFML2B KIAA1549 TCEA2 DHTKD1 SH2B1 EP400 MAN2A1 TTLL3 C12orf65 FBXO22 NRXN2 LRRC59 KRT8 NOC4L ANKS3 SNAP47 LRCH4 LRIG1 PIP5K1A LRRK1 IGHMBP2 WDR27 CBR1 CNTN2 ZNF286A PRSS8 CEP85 MICAL3 LHX4 FAM3C HDLBP RTEL1 BLVRB SYBU CDK5RAP1 ZNF404 ST20 MROH1 SAMD4B SNX19 TCF25 LINC00240 CIAPIN1 GNA12 BCAS3 GNE C1orf159 TRIM67 ANKS6 ZNF341 TSNARE1 LINC00304 NPEPL1 NUP210 PI4KB WIPI1 PPP4R4 LINC00888 FTSJ3 ACIN1 ZNF740 NOS3 CFI DYNC1H1 SCRN2 NSUN5 BCL7A COMTD1 ST6GALNAC1 NOXA1 ZC3HC1 TMEM229B PSME1 GGA1 VAC14 CARD14 MCEE COL5A1 SMYD3 DUS3L LZTS2 TEFM DQX1 RPS6KB2 MTR MIR4273 HOMEZ PIGZ SHMT1	up	*
GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS	0.0040057	0.0362223	0.4070179	0.2677245	1.332631	538	MUC5B CCL19 B3GALT5 MUC13 HS3ST1 FUT6 C1GALT1 GALNT14 AK4 GMDS ELOVL6 CHST6 GALNT6 XYLB UGT8 PRTFDC1 MUC4 FUT3 GCNT3 MUC16 GUCY2C CHST4 SORD GAL3ST1 B3GAT1 MUC5AC SMPD3 GALNT4 FA2H GMPS ACOT8 B4GALNT1 GPC2 ACER2 TYMS UMPS GALNT10 MUC20 B4GALT4 NME1 MUC6 GOLPH3 GFPT1 ALG1L DPY19L2P2 HS3ST5 DPY19L1 COASY ABCC5 GALNT9 RRM2 NME9 PKM XXYLT1 NME5 B3GNT3 BACE2 B4GALT7 CAD GNPDA1 FUT2 ALDOA ALG3 MGAT4B PIGO ENTPD5 PARP1 UCK2 ATIC VANGL2 ALG1L2 SLC25A13 GNPNAT1 ACSBG2 PDK1 EGF UCKL1 HAS3 GAL3ST4 MPI UPP2 EDEM3 POFUT1 SLC35C2 DCAKD SLC26A2 CHST3 CCL21 MAN1B1 XYLT2 DHODH COG7 PIGG ASGR2 LMF1 TK1 DTYMK TMTC2 POMT2 SRD5A3 GALNT3 GK5 ACSL6 GALNT7 CHPF SLC26A1 PFAS TSTA3 STOML2 MAN2A1 ACLY ABCA7 PPCDC PIGU DPY19L2 AATF DOLPP1 PIGX ALG8 ADCY1 CANT1 FKTN AMDHD2 NME4 HAS1 ACSF3 ELOVL4 COX5B FMOD TRAK1 NME7 VPS9D1 POMK SLC35B3 CHPF2 ADCY6 RPN1 ABO GNE ALG1 A3GALT2 BCAN PAICS GOLGA2 RFNG PIGL PDP1 FUT10 NPR2 ENO1 PIGQ MUC1 TK2 B3GNT4	up	*
MIR3065_5P	0.0016275	0.0183143	0.4550599	-0.2298251	-1.330950	381	NOVA2 OSBPL11 SECISBP2L CD55 CAT RAPGEF2 KCTD9 PLEKHF2 ELF2 SRSF7 S1PR1 CDC42 OTUD4 DNAJB14 RBM7 UBL3 NDUFAF7 KLF10 FOXP1 GLS SLC7A11 DACH1 ZMYM6 ZEB1 ARHGEF2 SOX7 PDE4D PDGFA GPM6A EIF1B KIF1C ROCK2 TLE4 ACSL3 REST UBE2E2 HNRNPUL2 AQP4 HOPX WASF3 ARL4A SLC25A32 PAFAH1B1 SPRYD7 SMNDC1 CRIM1 CPLX1 EFR3A ZDHHC20 UFM1 GPBP1 ARL6IP5 DCP1A VPS37A PKNOX1 MED28 PHACTR2 HECA WSCD2 ETS1 ADRA1A BMP3 CCDC50 ATXN1L PIK3R1 ATL2 FSD1L SLC10A7 NUDT15 TMEM192 EPPK1 ING3 CHORDC1 AZIN1 TCF4 DCAF5 ZBTB1 DCK PDS5B ZBTB11 ATP6V1A MAP3K2 CNTNAP1 MEIS1 SMAD2 EPB41L5 LRP12 UBE2D1 KPNA4 RBMS3 MAP3K4 NPAT JMJD1C SCAI DNAJB9 SAMSN1 RORA NRP2 DOCK4 ENY2 SPATA13 SCLT1 CDKN1B ZNF800 LNPEP SSB CLOCK PLEKHA2 CCNT2 SRSF11 PRTG UBE2W SGIP1 SCAF11 HMGB1 CRIPT PYROXD1 ATP2B4 NFIL3 B3GALNT2	down	*
MIR33A_3P	0.0025325	0.0256480	0.4317077	-0.2290780	-1.330467	371	RTKN2 AKAP5 SASH1 DENND5A CPEB2 ATXN3 SNX10 CLEC12A CLDND1 ST6GALNAC3 RUNDC3B CCDC88A RASAL2 CITED2 S1PR1 NR3C1 CD1C NFATC3 FAM49A PPM1D CD8A CCNL1 SH2D6 NCEH1 ANXA5 REV3L CAV2 SLC7A11 MS4A1 PPP3CA EPM2AIP1 HNRNPU UBE2D3 GLDN FABP5 KCNMA1 MPEG1 LIMS1 ZFAND5 OSTF1 MAP1LC3B MYO1B SPAG9 UBQLN1 NPAS3 GPR85 AQP4 SHE CCND2 CLK4 PRF1 CCSER2 DNTTIP2 CPT1A CUL5 NUS1 AFF1 LIN54 SPIN1 CREBRF ELF1 PHTF2 PHACTR2 EBAG9 NECAP1 SF3B1 CD48 CNTN4 FOXN2 DHX15 HSPA13 CREB1 KBTBD8 CXCL5 PELI1 TSHZ3 PEA15 STRN TBRG1 CNOT7 PCDH17 MRGPRF ACADL GNA13 ARAP2 HSPA2 INTS6 RPP30 YAF2 CEP170 SEC63 FBXO30 DIXDC1 MEX3C GPD1L JMJD1C SCAI FAM126B MMD RORA NRP2 GRB10 YTHDC1 PSIP1 TMEM184C TMEM50A CFL2 CCDC112 CENPC ZNF800 CLOCK PRKCH	down	*
GO_CALCIUM_ION_BINDING	0.0050326	0.0429982	0.4070179	0.2683616	1.330329	506	CPS1 SYT8 MMP13 CDHR2 SCIN HABP2 PCDHGA10 CDH17 SPOCK1 FAT2 S100A2 PDCD6 PRSS2 DOC2A PCDHGA9 CIB2 PCDHGA5 PSPH CLGN PCDHGA7 STAB2 PCDHGB2 PCDHGA6 PCDHGA1 PCDHGB3 TENM2 PCLO PCDHGB6 PROC CALML6 PCDHGB4 NOX5 PLS1 CIB1 GUCA1B FSTL4 MYL6B PCDHGA11 AOC1 PCDHGA8 ASTN2 SYT12 CAPN13 PROZ TNNT2 MELK CLSTN3 CBLC HRNR PCDHGA12 PCDHGC5 THBS4 PCDHGC4 P4HTM FLG ADAMTS13 PCDHGA4 EFCAB12 PCDHGB7 ANKEF1 PCDHGA3 SYT2 CAPN12 CAPS NOL3 PON1 EFCAB11 CAPN8 DNER VWA2 EFCAB6 LRP2 MCTP2 FAT1 CRB2 PLA2G2A ATP2A1 PLCH1 TESC SLC25A13 ENPP3 CDH3 CPNE1 EFCAB1 EGF RAB11FIP4 PLCG1 PCDHGA2 ITPR3 CAPS2 TBC1D9B EDEM3 DNAH7 NINL EFCAB2 MAN1B1 S100A16 TPO COLEC11 MEGF8 S100A9 PCDH9 VIL1 SYT1 CGREF1 DLK2 GALNT3 FKBP14 S100A13 PRRG2 ENPP2 EFCAB8 PCDHGB1 EFCAB7 PLCH2 EFCAB10 DGKA EFHC1 KCNIP3	up	*
SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN	0.0003653	0.0057636	0.4984931	-0.2193094	-1.329877	541	GPR15 CAT PTPRE LIPA MYD88 SLC39A8 WBP4 NFATC3 RBM7 RRAGC ASAH1 BTG2 EIF5 PBX3 PICALM ABCG1 KLF10 KLF6 LCP1 PPP2R2A ASH2L NFE2L2 LAMTOR3 CRK UBE2D3 BAG1 MCL1 ATP6V1B2 RHOB PTPN12 PPT1 SCP2 BIRC2 EPOR PTPRO PIP5K1B ITM2B MAP1LC3B MED6 ATP6V1D VRK2 GRK5 ZNF24 SPAG9 SEC24B NFKB1 RIT1 PDE3B PTPRC CTBS M6PR TAF9 CD53 RNF139 EVI2A CUL5 SLC25A32 OXSR1 TM9SF2 USP16 COPS4 ACTR2 PIAS1 RAB6A PRCP SNX3 MYLIP RBPJ ETF1 PDHX WASF2 CREM CTSS DCTN6 UTRN SF3B1 PSMA1 GABPA RAC2 CYP2A6 DNAJA1 JAK1 DHX15 IPO7 GLIPR1 IDS CREB1 HSD17B12 CAP1 AP3B1 YWHAZ RASSF2 RALB CGGBP1 DEDD ACSL1 GRSF1 RHOQ CD164 ECI2 PSMD12 ICAM2 SRSF6 PKIA AZIN1 DUSP5 GALC ATXN1 CSDE1 UTP3 DOK2 NPTN CLEC2B PDE4B CCNH SMAD2 GTF2B PITPNA PDLIM5 TNFAIP8 YAF2 SF1 CDC16 NBN DCTN4 SRP72 CYB5R4 VPS4B HSPA8 IPO5 G3BP2 ARPC5 PTEN LYST DNAJB9 ANXA11 THEMIS2 DAZAP2 LPAR6 SFPQ EMC3 CNOT8 SMAD4 RNF13 IRF2 YTHDC1 UBAP1 PXMP4 CLOCK TGOLN2 CMPK1 SLC38A2 PTDSS1 GPR137B UBE2N TRIM13 SCAF11 SLC25A40 DDX21 ZNF22 DLD PYROXD1 RCBTB2 SNRPN SKAP2 NFIL3 POLR2B RPA2 RAB1A RC3H2 RNGTT ORC4 AIMP1 CFLAR CCNC IL32 CAPN7 RPP14 NFYB MYO5A ADCY3 PNP UBE2D2 ALDH3A2 SON PUM2 CRLF3	down	**
MIR613	0.0031596	0.0303325	0.4317077	-0.2408252	-1.329399	278	TSPAN4 SOWAHC TBX3 TTC7B BDNF MMRN1 CORO1C CITED2 SLC25A30 NEDD9 CBL NFATC3 ZEB2 SEMA6D TRA2B PICALM FOXP1 HIPK3 EIF4E ASH2L PLXNA4 ANKRD29 HNRNPU FLI1 SLC7A2 CPED1 HMGN1 KLF4 THBS1 ZNF24 MGAT4A PIK3C2A WDR48 PEAK1 NCOA1 C2orf69 NINJ1 ELF1 PDIK1L CREM UTRN LRCH1 HMBOX1 ETS1 SNX2 DDX5 PRKCE CAP1 SLC10A7 YWHAZ CEBPZ TAGLN2 CDK14 FOSB AZIN1 AP1G1 KCTD10 VAMP4 ATP6V1A NAB1 MYOCD ADPGK HACE1 RNF138 CTTNBP2NL WDR1 RAB5A METTL21A ACTB MEX3C TIMP3 EDN1 RNF38 MMD SAMSN1	down	*
MIR3662	0.0001072	0.0020529	0.5384341	-0.2100768	-1.329090	789	RTKN2 IL1A ST8SIA6 OSBPL11 OSBPL1A ZC3H12C LRRC8C PRKG2 RDX CLDND1 RAB3C LRRFIP1 PTPRB RUNDC3B KL TRPC3 MMRN1 CCDC88A SEC22C CALCRL BMPR2 PLEKHA1 TSHZ1 EOGT CBL ZBTB2 MOB1B ACER3 SPCS3 TMX4 ZEB2 DNAJB14 ARHGAP29 RBM7 STARD4 DNAJC18 HECW2 LIFR RAP1A PPP1R15B ZDHHC2 MAP3K8 RNF144B CNTD1 FZD4 ABCG1 HIPK3 PAQR3 CAMTA1 PAG1 SLC7A11 EIF4E PPP3CA SRSF2 SPTBN1 KANK2 TFEC ZEB1 EPM2AIP1 HNRNPU PDE4D TCF7L2 GPM6A MSR1 MTMR6 FOXO1 PPP6R3 PPM1K LIN7C RUNX1T1 REST HAUS2 PLEKHM3 ZADH2 THBS1 NPR3 PDE8A MGAT4A UBE2E2 SHC4 USP44 CXXC4 ELK3 PEAK1 KIAA0408 PAFAH1B1 PRDM5 PDE1C IKZF5 EFR3A CNOT6L MAPRE2 LIN7A ACTR2 FAM102B LIN54 RBPJ PPIL4 CREBRF SLC8A1 ID4 FLT1 METAP1 SYNPO2 PKNOX1 DDHD1 PHACTR2 NEK7 APPL1 CNTN3 UTRN HECA GABPA NXPE3 TBC1D12 FERMT2 SP3 PIK3R1 PRKCE CREB1 KBTBD8 RC3H1 ZBTB24 SH2D4B MSANTD2 RBM22 TRAK2 TCP1 TNFRSF9 OGFRL1 NAA30 CGGBP1 EPC2 LETM2 CYP4A22 CELF2 GAS2L3 AGFG1 CDK17 PKD2 SLC35F1 MAPK8 PKIA KLRC2 NAA16 BTBD7 ZFAND6 EPHA3 SORT1 PPP2CB GOLGA8R PBRM1 STRN PHF3 NR2C1 NDUFA5 ZBTB1 DCK PDS5B BAZ2B RSBN1L PDE12 GOLGA8H NAB1 C16orf72 MAP3K2 GNB4 ANKRD12 GNA13 GPR18 LTBP1 ATAD2B INO80D RNF2 GEM ANKLE2 LDLRAD4 INTS6 MIER1 FKBP1A CTTNBP2NL CEP170 MGAT2 SRP72 CDC42EP3 LRP12 TTLL7 UBE2D1 BRWD1 SSH2 GRIN3A SRSF10 KPNA4 RBMS3 LYSMD3 BCAT1 RASSF8 SCAI PAK2 SNAP29 FAM126B PRKG1 CAMSAP2 SAMSN1 C21orf91 RORA THEMIS2 SFPQ SLC44A5 ANO6 EVI5 TRIM36 ZBTB44 ZNF326 KALRN ACVR1C PLAG1 C5AR2 EXPH5 SVIL ZNF385B ZNF800 ENDOD1 HIPK1 SSB CLOCK OSGIN2 RB1CC1 HP1BP3 DYNC1I2 KBTBD11 ZBTB7C PLXDC2 FAR1 PIGK CTDSPL2 PRTG VPS36 SPTY2D1 PIAS2 WNT5A SGIP1 PCDH15 ARHGEF12 FNDC3A FAM218A MAP3K1 B3GALNT2 WWTR1 CNTN1 WDR26 TRIM25 RNGTT ORC4 CLVS1 GUF1 CEP68 EDIL3 GNPDA2 CFLAR CCNC IMPACT AKAP13 METRNL NFYB GPATCH2L SREK1 ERLIN2 KLRC1 ENPEP ANKH CBFB UBE2D2 CBLL1 ZBTB6 PLXNC1 YAP1	down	**
HOXB4_TARGET_GENES	0.0009586	0.0122991	0.4772708	0.2607074	1.328924	943	MNX1 EPHB3 C1GALT1 MDM1 IGSF9 TICRR MCM10 AP3B2 XYLB IGF2BP3 TIMELESS C21orf58 DDIT4 LINC00941 NDC80 PLEKHA6 BRCA1 BET1 CREB3L4 MRPL46 HILPDA SAYSD1 TTC26 CEP70 EFNA4 CDCA8 FIGNL1 SMPDL3A SPATS2 TYMS NWD1 PLS1 COPB2 XPO5 VILL AVL9 ZWINT ZNF608 CCT2 DCTN2 LSM5 LMLN FAM220A AARS2 ASAH2B GOLPH3 MAP7 NLE1 STAP2 TP53BP1 PCCB COPG1 CLHC1 POLA2 SAE1 YKT6 GTPBP3 LARS2 ZNF860 ABCC5 ANKRD19P TTC22 ASPHD1 SETDB1 CCDC114 NME9 PKM LINC00511 PYCR2 AP1M2 LIG1 EME2 LINC00265 ZNHIT1 CCDC148 GET4 C7orf50 SCAMP5 FBL SLC25A39 RPAP2 MRPS11 EEFSEC FBXL8 ETFA TST NOL3 C4orf47 ZNF713 MGAT4B TFCP2 TULP3 COQ9 ZNF346 CNPY2 PPP1R37 TRIT1 CKLF RNF216 MRPL36 RASSF6 CMAS PPIL2 FASTK ASF1B MRPL37 FAM221A PABPN1 HDGF CENPJ CENPH ANKRD54 OAT NPM3 STAT2 MCAT MKRN1 ACTR3C SDCBP2 ZNF584 NARF PDK1 ANAPC7 POLR1C TNPO2 C16orf71 TAF6 METTL3 OARD1 SLC2A13 MTBP SNRPE GOLGA5 ABHD4 ANXA2R KPNB1 TPD52L2 RNF44 CHCHD2 NET1 POLR2H MZT2A GOLGA3 ZNF687 ELMOD3 CEP63 CCDC142 DPP3 TUBG1 CCDC134 SNX27 C19orf47 TRMU TRADD NMRAL1 MRPS34 YIPF3 ZMAT5 IQCG LRRC8D LMF1 MORN2 DNM1 CENPQ POMT2 HECTD1 ANP32E PKP4 MAPK10 ASNS LCLAT1 SYNGAP1 IQCH SIL1 NUP85 ZBTB45 CLTB RBM33 IP6K2 YARS2 BCDIN3D-AS1 DHTKD1 KDM3A KLC4 EFCAB7 L3MBTL2 STOML2 PLD1 WDR34 RIN1 ZCCHC17 FBXO22 ZNF497 HMGB3P22 USP2-AS1 CHMP4C TRIM56 KRT8 RPL7L1 RPPH1 SURF2 ANKS3 UIMC1 PYGO2 SLC35A3 CACNB3 NSD1 RTEL1-TNFRSF6B GINS3 LRCH4 STMN3 AATF PFKFB4 CYP4F12 CCNG1 WDR27 ANK3 GOSR2 MST1P2 NUP62 FARSA NDUFV1 B9D1 NCDN ULK4 PRIM1 MLXIP RTEL1 SYBU ACKR2 TTC31 WDR4 HK2 OSBPL10 N6AMT1 TTC1 STK25 TRIP4 NBR1 R3HDM4 TRIP6 FBXW11 ST20 SAMD4B RARRES1 KIAA0825 SNRNP70 SLC35B3 UNKL MXD3 DIP2B ATG2A UQCRQ ZNF131 CIAPIN1 POLR1B PNKP SYNRG GOSR1 MAPK8IP3 RPN1 POLR1A EIF4G1 E4F1 CELSR3 TIMM44 FIS1 LEMD2 MRPS27 ARMC10 SART1 RAD1 SLC39A1 NAT10 MUC1 TK2 TRUB2 ILVBL BRSK2 PPP1R14B PTPN13 SART3 DDX41 ACTR5 FTSJ3 TRPC4AP SETD5 PRKAG1 ALKBH2 ZNF629 PARP2 RNF14 TPM1 TMEM62 SHROOM1 ZNF740 TNFRSF1A WRAP73 METTL4 SH3RF2 RAB40C TRIM52 CRAT EIF2B1 ZNF598 PCNT NOXA1 NOD1 FOXP2 SCAMP4 CYB5RL MRPL43 LTK DLGAP1-AS2 NSL1 MECOM TM9SF1 MARVELD2 GATA6-AS1 ARHGEF19 LINC00271 SERTAD4-AS1 GCC1 PGAM5 CCDC24	up	*
ZNF260_TARGET_GENES	0.0013499	0.0160504	0.4550599	0.2631756	1.328768	687	HMGA2 MEGF10 RUVBL1 DNAH2 PARPBP GMDS FBXW8 ZMYND8 CHEK2 C17orf75 STOX1 TSHZ2 DDIT4 TTC25 RAB3IP TSFM METTL1 TUBB2B GINS1 CDCA2 NOL12 ANKRD24 TTC26 NUF2 WDR70 ZNF221 ZNF283 ZNF608 COQ3 UQCC1 LSM5 NUB1 TAMM41 NME1 AARS2 TOP3B TMEM41A KCNH2 ZNF391 C9orf116 FBXW9 CCDC77 GTPBP3 RBM28 MRPL3 ANKEF1 EMG1 TARS2 PSMG4 EME2 HEBP2 DNAJC9 THAP10 RABEP2 DET1 MNAT1 TFCP2 OSBPL7 UQCR11 GEMIN4 TXLNB SUPT5H CBX5 ANAPC5 PABPN1 CDK12 SSBP1 ZNF260 C1orf112 CCNJL MRPS2 ENPP3 KLHDC9 TSPAN31 TMEM79 PSMG3 TNPO2 RNF207 SEMA3A ATAD3A RNF150 SNRPE ZNF827 PSMC4 WDR24 ANXA2R KPNB1 CHCHD2 GRAMD1A CCNE1 SMG5 NDUFA11 SEC16B ZNF233 GALK2 ADNP MTOR JOSD2 DHRS4-AS1 MRPS34 COG2 DNM1 COPS7B ZNF234 JMJD4 MLEC SOX2-OT CPE MTND5P11 LIN37 GFM2 ZNF282 POLD1 FAM207A PRRG2 CCDC159 ZBTB45 POLB NIF3L1 GEMIN6 LSG1 EFCAB10 VPS25 ASB6 FAF1 DUS1L FBXO22 FAM136A ACLY PPP1R3D PPP6R1 KRT8 MRPS33 RPL7L1 UBL7-AS1 RAI14 NOSIP SLC38A7 NMNAT1 ANKRA2 SNRPD1 SNAP47 TFAP4 MRPL53 SLC35A3 RTEL1-TNFRSF6B POLR2J3 STMN3 NDUFS7 YIPF2 RCC1 IGHMBP2 ZNF780A MST1P2 AKAP6 GNAL ZNF580 ZNF622 NME1-NME2 PRPF18 ZNF224 BCL9 TSC2 RBM42 ZNF195 BANF1 RTEL1 POLR3B TUBGCP4 STAT6 CDK5RAP1 ZNF404 PRPF31 BMS1 TRIP4 GTF3C5 SAMD4B MRPL21 LINC00240 TMEM101 AURKAIP1 SNUPN SIRT6 GOSR1 ZNF793 POP4 ZNF205 ZNF354B BPNT1 MRPS27 PIGL DCDC1 PIGQ MRPL48 NDUFB7 CLASP1 DDX41 ALKBH2 TTC5 SLC33A1 INO80B ZNF554 METTL18 HEXIM2 MORN4 SETD1A ANO8	up	*
RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_DN	0.0025629	0.0258499	0.4317077	-0.2330891	-1.328439	326	SLC31A2 EREG IL1A ABHD5 MCOLN1 LRRC8C LRRFIP1 SMIM12 ARRDC4 CD44 BACH1 CORO1C MYD88 ARL8B ALAS1 MKNK1 AGPAT4 TEX2 NUMB CD36 BMP1 HBEGF SBDS SGMS2 GM2A MTF1 BZW1 LUZP1 KLF10 KLF6 ABHD6 NDEL1 TUBB6 FBXO8 FABP5 SYNPO ITPRIP AHNAK PLAUR AFAP1L1 KLF7 ATL3 CDKN1A HPSE PLEKHB2 INHBA OXSR1 GPR157 N4BP1 FKBP15 NRBF2 MTPN VAMP3 SAR1A PHACTR2 PDCD6IP ANKRD9 CPEB4 RAB31 GAS2L1 HRH1 TREM1 OSTM1 RCAN1 GLIPR1 KLHL18 RAB8A LPCAT2 TINF2 SNRK ATP6V0D1 CALM1 NIPAL4 PSMD12 EHD2 EPPK1 EHD1 KCTD10 C1orf116 CDC37L1 GNAI1 FAXDC2 ANKRD13A STX12 ADAMTS15 PGGT1B	down	*
TGCTTTG_MIR330	0.0046586	0.0405343	0.4070179	-0.2417270	-1.327963	255	SOSTDC1 BACH1 QKI BMPR2 DYRK1A TGFBR3 OTUD4 NFATC3 ZBTB4 ATP2B1 NCEH1 TRA2B RAP1A PLXNA2 PICALM LUZP1 ZNF410 EIF4E LHX6 HNRNPU GPM6A TIPARP ZCCHC24 ZNF423 TJP1 ITPK1 ID2 SMAD7 PAFAH1B1 FOXN3 RAB6A MTPN BTG1 ETF1 SLC25A3 SNAP23 APPL1 JPH1 MTMR9 APBB2 FYTTD1 SKIL MBNL2 RC3H1 TRAK2 NAA30 YPEL2 HIVEP2 RUNX3 STXBP3 TFEB SLC8A3 KAT2B PHLPP2 MBNL1 PRDM8 BMP2K PDLIM5 RLF CEP170 TRAPPC8 BRWD1 CREBBP FNBP4 SIN3A FOXJ2 PRKG1 PAIP2 KIF1B FGFR1 ITCH CCND3 RHOT1 WDFY3 MACROD2 BMI1 MIER3 ZBTB44 CHP1 ZNF800 HIPK1 MAPK1 MYH10 CMPK1 EFNB2 CSNK1G3 CTDSPL2 API5 CAPZA1 PCMT1 TYRP1 KLHL9 RNF111 FCHSD2 NR4A3 TRIM3 GTF2H1 YOD1	down	*
GO_CELLULAR_PROTEIN_CONTAINING_COMPLEX_ASSEMBLY	0.0013660	0.0161591	0.4550599	0.2617997	1.327592	795	PRLR SCIN FGA HELLS HJURP RUVBL1 CDC45 NUP107 BAIAP2L2 COIL CENPF CPSF6 COA1 AVIL PRRT2 CABIN1 TSPYL5 ANLN NDUFS6 BAIAP2L1 CENPA ACAD9 SOX9 MCM4 MCM2 EFNA5 EIF3B MIS18A ARHGAP40 CAND1 SRPK1 VILL CDT1 CCT2 UQCC1 MICALL2 DNAI1 PPP1R9A RUVBL2 ARMC4 NDUFB8 DLG1 NLE1 CHAF1A WASF1 CENPL SPTB NDUFS2 ATR FGG MCM7 CENPW TEKT2 ZNHIT6 ERAL1 CCDC114 PCDHGA3 FHOD3 MCM3 CHAF1B PFN2 ANG PSMG4 DNAH8 CDC42EP1 PSMD4 CENPO COX19 CLIP3 PIH1D1 DNAAF3 MRPS11 GEMIN7 NOL3 ERCC2 TRPV4 MNAT1 CCDC40 PARP1 PSRC1 GEMIN4 TTBK1 DRC1 ASF1B PAK1 LRRC6 CENPJ CENPH ARPC1A PICK1 GMNN ERC2 ALDOB PRPF6 ACTR3C DHX33 NUP205 ACTR3B EGF TAF6 COA4 TRAPPC12 SNRPE DNAH5 UQCC2 NOP2 PSMC4 DIAPH3 CENPP GBP5 EIF6 VBP1 TAPBP CEP192 TUBG1 NDUFA11 TAPBPL COA3 VPS41 DNAH7 FOXRED1 CCL21 MTOR TRIM9 LONP1 CCDC151 MRPL11 HIRA SPTBN5 COPS7B ADAR DBN1 CENPQ MSRB2 HIP1R SPTBN2 GEMIN5 VIL1 CLTA SPAG1 NDUFA13 PRMT7 TM9SF4 COG4 TWF1 ESR1 COX10 CLTB CENPK BAZ2A GEMIN6 CENPV C15orf62 CKAP5 HNF1B CENPM TUBG2 RPA1 WNT10B CDK5RAP2 CLINT1 MCM6 TBCA CELF4 CENPT SRPK2 FCHSD1 MCM5 DNAI2 CD2BP2 SNRPD1 DDX23 SNAP47 EIF3D ADD3 SRSF1 HAX1 CHRNA3 NDUFS7 LSM4 TXNL4A SF3A2 EIF3K PRMT5 NDUFV1 AP2S1 PRPF18 SMARCA4 SCO2 DBNL SNRPD2 DENR TUBGCP4 USP39 WDR77 PRPF31 DNAH1 RAD51 FMOD GTF3C5 SOX12 NDUFA8 SNRNP200 CHMP2A NDUFS8 CTTN NUBPL SNUPN TARBP2 XPC CAMSAP3 CENPE EIF4G1 ADRM1 SWI5 TP53 PRPF3 GOLGA2 ALOX15 SNRPC UBE2C MSRB1 UBTF MRPL20 SART1 ZMYND10 SMARCB1 ATF7IP DDB2 NDUFB7 RRS1 DNM1L IMMP2L CLASP1 NUP93 COX17 SART3 BRIX1 RANGRF CORO1B ERCC3 GEMIN2 SNAP25 PMEPA1 CLNS1A POGZ NDUFAF6 EIF2D RPL23A VPS18 EID2 MRTO4 DNAAF1 LUC7L3 DRG1 SHQ1 VPS16 WDR63 AXIN1 PRPF19 AKAP9	up	*
GO_GLYCEROLIPID_METABOLIC_PROCESS	0.0041448	0.0371727	0.4070179	-0.2316168	-1.326922	323	GPD1 LPIN2 PNPLA6 ABHD5 FABP4 CAT PLA2G10 MBOAT2 TTC7B SIK1 INSIG1 PCSK9 FIG4 LPL INPP5K PTPMT1 CAV1 GPCPD1 PLEKHA1 INPP5A AGPAT4 PLA2G7 SLC44A2 SERINC1 ABHD6 APOC1 PDGFA RAB14 FABP5 MTMR6 DGKE PIP5K1B ACSL3 SOCS2 SOCS5 PLBD1 CDS2 PIK3C2A PLEK CPT1A PAFAH1B1 PIK3R5 EFR3A PI4K2A SACM1L DDHD1 SOCS3 INPP5B PLEKHA3 PIKFYVE MTMR14 MTMR9 PNPLA8 PIK3R1 PI4K2B LPCAT2 PANK2 IP6K1 ACSL1 PLCG2 PNPLA2 DGKG DAGLA PNPLA3 CHPT1 DDHD2 ENPP6 DPM1 FPR2 MTMR2 PIK3C3	down	*
GO_REGULATION_OF_CELLULAR_COMPONENT_SIZE	0.0049459	0.0424555	0.4070179	-0.2344938	-1.326853	304	TNR SEMA6B SEMA3G SEMA6A SWAP70 SLC12A6 RDX DPYSL2 TRPV2 BDNF SHANK3 TMOD3 BAG4 KANK3 MYADM BAIAP2 BMPR2 CDC42EP2 ESAM CIT RHOA SEMA6D SEMA3B RILP TTL PICALM SPIRE1 PLXNA4 TMEM123 ISLR2 NDEL1 SPTBN1 WNT3A KCNMA1 TRIM46 SLC12A4 VASP COTL1 AQP4 ACTR3 CAPZA2 PLEK DSTN IL7R PAFAH1B1 RUFY3 ADD1 ACTR2 LMOD3 HCK MTPN CLN8 SRF NCKAP1L KANK1 MYO1C TMOD1 PPP1R15A CCR7 IFRD1 GMFG PRKCE GRB2 CREB1 RTN4R SNX9 WHAMMP3 VAV3 ACTN2 MACF1 CLCN6 IST1 ICAM1 ARPC2 WDR1 LMOD1 SEMA4A RTN4 RAB5A CDC42EP3 TMOD2 ARHGAP18 ULK2 SIN3A RET EDN1 ARPC5 PTEN	down	*
GO_NEGATIVE_REGULATION_OF_CELL_DEATH	0.0001074	0.0020549	0.5384341	-0.2116042	-1.326842	776	FFAR4 PTCRA SMAD6 LIMS2 ANGPT4 RTKN2 IL1A HMOX1 TEK EDNRB SGK3 TBX3 GATA2 IL1B CAT WNT4 RAMP2 BDNF FYN CD44 BAG4 CAV1 CITED2 MYD88 ADCYAP1R1 C5AR1 HMGCR APIP FGF10 BCL2A1 GAS6 CBL USP47 RHOA ANXA1 ARHGAP10 MIR146A CLCF1 DNAJC3 FBXO7 CARD16 ADA LMNA MTRNR2L8 ITGA5 BTG2 HSPB1 RNF144B ANXA5 FOXP1 HIPK3 BFAR SLC7A11 SERPINB9 GATA3 RB1 TRAF6 NFE2L2 GRN SFRP1 SPRY2 WNT3A KANK2 ARHGEF2 MAPK8IP1 TCF7L2 TXN BAG1 MCL1 FOXC2 EVI2B IL10 AGO4 MTRNR2L3 ARRB1 SNAI1 ITPRIP PPT1 FOXO1 BIRC2 BNIP2 SLC46A2 AGR3 YBX3 KLF4 PLAUR NES HYPK REST RRM2B ROCK1 DAB2 THBS1 SOCS2 GRK5 ATG7 TMBIM1 PDE8A NFKB1 CDKN1A AXL MIR24-2 CCND2 UBE2B TAF9 FCER1G DUSP1 PINK1 WFS1 HTT IL7R GNAI2 MIR17HG PIAS1 GNRH1 HCK TOPORS CLN8 NCKAP1L PDK4 UFM1 WNT9A CNTF IL6 PSEN1 SOCS3 IL2RB NDNF JUN MITF NOTCH1 CPEB4 MAP4K4 HSPA1B PLK3 DNAJA1 APBB2 BAG5 CCR7 PIK3R1 ACKR3 CREB1 MALT1 RPS6KA1 REL DOCK8 YWHAZ TNFRSF10B CLN3 CD34 PLCG2 GPR37L1 RRN3 ADNP2 UBB PELI1 CACYBP SRSF6 PRKCG MAPK8 CD74 NAA16 WNT11 ZFAND6	down	**
MIR9_5P	0.0012893	0.0154807	0.4550599	-0.2277281	-1.326526	412	TRIM71 SLC31A2 STAC CPEB2 PRKG2 LYVE1 SIK1 INSIG1 AATK BAG4 THAP2 LAMP1 EOGT TGFBR2 NFATC3 HPS5 DNAJC3 SGMS2 LMNA CHMP1B FOXP1 HIPK3 GLS GPBP1L1 TNS1 ANKRD29 ARHGEF2 YBX3 ITM2B SETD9 REST SLC7A8 ADAMTS9 DENND3 SOCS5 FBXL3 PDE3B M6PR CCSER2 PIK3C2A DSE SLC6A6 OXSR1 UBASH3B TBC1D4 CRIM1 BACE1 SEC31A CMTM6 CNOT6L PI4K2A C16orf54 PDK4 MCMBP MYO1C CREBRF SLC8A1 VAMP3 ID4 WASF2 KIF13A HCFC2 CNTN3 UTRN TMTC1 CPEB4 KCTD12 ADRA1A C11orf58 CCDC50 ATP11A NXPE3 FOXN2 RHOJ FYTTD1 HUNK KLHL18 PCGF5 FRYL ATL2 AP3B1 RALB PALMD PPM1F GRSF1 SLC25A24 RHOQ SORT1 DDHD2 VAV3 TESK2 KCTD10 MTMR2 PDE12 CNOT7 MAP3K2 COL15A1 MYOCD ANKRD13A RXRA ABL2 ITPRIPL2 ESYT1 DIXDC1 ZDHHC21 RBMS3 ULK2 TMEM109 FNIP2 FAM126B C21orf91 FAM13C TLK1 EHD4 SLC44A5 MIER3 STARD13 NAF1 ARHGEF17 TBPL1 HIPK1 ATF2 SLC19A2 CLOCK FAM8A1 FBXW2 DYNC1I2 CCNT2 PRTG TRPM7 PRDM6 TSC22D2 CAPZA1 ATOH8 TES CCNDBP1 DR1 MAP3K1 RNF111 B3GALNT2 NR5A2 NTAN1 ITGA6	down	*
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN	0.0012278	0.0148960	0.4550599	0.2611994	1.326441	810	TRIP13 FAM201A GALNT14 RUVBL1 AK4 BDH1 RPGRIP1L COIL TRNP1 FLVCR1 MPP6 SEMA4B SLC2A1 CHST4 CCDC113 SORD ECE2 HILPDA TTC26 EBF3 ALDH18A1 SFXN1 KNOP1 UMPS EIF3B MCM8 XPO5 COQ3 COX11 WDR90 NUB1 RANBP1 MANSC1 CLPTM1L BZW2 ZNF74 DCBLD2 PUS7 NUP155 WDR3 MYO10 TMEM177 SLC29A2 POLD2 CENPW DPCD SMYD2 TTLL12 RBM28 PDCD5 GCAT AKAP1 DUSP23 SOX4 L3HYPDH ZNF530 FAM162A PSMG4 ZNF618 C7orf50 MAD2L1 SLC25A39 DCTPP1 DNAAF3 HES6 AKT2 OXER1 ETFA RAD18 MRPS30 PHB ERCC2 ALG3 MGLL SLC25A10 HSPBP1 CCDC138 SKP2 DYRK2 PES1 GEMIN4 MRPL36 CBX5 ANAPC5 HDGF UCK2 BCAS4 CCT3 GOT2 DHX37 MCAT MIR570 DHX33 GNPNAT1 POLR1C TNPO2 MRPS12 RNF207 TMEM120B ATAD3A NLN NOP2 LAPTM4B FGFR1OP STK11 PA2G4 ZNF692 RANGAP1 NRGN HSPA4L MPI POLR2H SNRNP25 TELO2 PDCD11 SCLY ZNF671 NDUFA11 PSMA5 TRMU C12orf45 MRPS34 DHODH TUBB2A PTGES2 SLC37A4 HMGN3 MORN2 COPS7B ENAH MYBBP1A MSI2 ZNF816 GEMIN5 MRPL4 KIF20B GUSBP1 NOC2L DNAJC11 CLTB RMND5B BAZ2A GEMIN6 CENPV PFAS TIMM13 GOLM1 L3MBTL2 KLHL23 DCUN1D5 CENPM TWIST1 RRP9 GPATCH4 POP7 FAM136A MRPS23 NOL6 SRRT MRPL24 PEX5 MRPL41 MED24 TMEM147 WDR35 HEATR1 LSM7 CLUH LTV1 CREB3L2 RNASET2 TIGD7 RCC1 TXNL4A AP4B1 ZDHHC11 MARCKS NEFH TSR1 PRMT5 STRBP NUP62 FARSA MRPL14 AGMAT ALMS1 RPS26 TM7SF3 SLC2A5 SCO2 DZIP3 DDX54 VDAC1 MRPS25 DOHH NME4 TUBGCP4 PDAP1 ABCF2 WDR4 WDR77 PRPF31 MLLT6 BMP8B N6AMT1 GADD45GIP1 CHMP1A MROH1 ZMYND19 ERGIC1 RDH10 MRPL21 LLPH SNRNP70 FAM118B LRG1 RHOT2 UBAP2L AURKAIP1 CIAPIN1 CLEC11A POLR1B SPR TCF3 POLR1A EARS2 ADAM15 ALG1 ANKS6 TBL3 ARMC10 SFXN4 DTD2 SLC35G1 PWP1 PPP2R5D DHRS9 RAD1 NDUFB7 RRS1 MRPS26 TMEM201 PPP1R14B ACTR5 ACSL5 IFI16 ALKBH2 TTC5 STK33 FGFBP3 DHX57 MRTO4 SLC40A1 LUC7L3 RNF126 PM20D2 KLHL42 SRM PPARGC1B MRPL12 DFFB	up	*
MIR548AR_3P	0.0006270	0.0088472	0.4772708	-0.2229859	-1.325516	489	GCSAML ADPRH SOWAHC ZC3H12C ATXN3 SIK1 MED4 QKI BMPR2 ARL8B MEF2A TGFBR3 C3orf70 TET2 MOB1B ATF7IP2 PPM1D ENTPD1 EIF1 MTF1 SDE2 BZW1 FZD4 SPIRE1 CAMTA1 PAG1 ABHD6 EIF4E FOXJ3 ZEB1 TFRC ZYG11B FLI1 PTPN12 TAPT1 SULT1C4 PPP6R3 FAM76A HYPK REST KLF9 ZFAND5 VASP TMED5 KLF7 MYO1B GPR85 HNRNPUL2 UXS1 CXXC4 PLEKHB2 N4BP2L1 UTP23 TM9SF2 BCLAF1 SMNDC1 CNOT6L PIAS1 SERTAD2 FLT1 VPS37A DNAJC27 PKNOX1 MED28 EBF2 NEK7 PIKFYVE HCFC2 DHH RAB31 CNTN4 EPC1 FERMT2 SKIL SP3 PIK3R1 ACKR3 PCGF5 HERC1 THUMPD1 OSM KBTBD8 TMEM167B SLC25A24 CTTNBP2 CALM1 FOXO3 MSMO1 SLC4A5 NAA16 CHRAC1 PHF3 PDS5B ZCCHC10 MAP3K2 ATXN1 C8orf37 CSDE1 PPP3R1 CLASP2 ACYP2 MACF1 LTBP1 ADAM10 CALB1 ARPP19 INO80D HACE1 RNF2 RPP30 PIP4K2A CXCR4 TRAPPC8 TAB2 MEX3C BRWD1 G3BP2 ZDHHC21 STAM2 CUL3 RNF38 SCAI PAK2 FNIP2 PTEN CHCHD7 NR3C2 ZFPM2 GSPT1 SPOPL PURB SLC44A5 SMAD4 EVI5 MIER3 USP48 ZBTB44 MAP4 PSIP1 ACVR1C UBR2 CDC14A FJX1 DKK3 ZNF106 ATF2 CDC42BPB ADAMTSL3 PIK3CG XRN2 SV2B TRPM7 PIAS2 SGIP1 IER3IP1 GPR137B VSTM4 WDR47 PDE7B GABPB1	down	**
MIR4503	0.0046182	0.0402942	0.4070179	-0.2434317	-1.325422	223	SLC6A4 SC5D MS4A7 CPEB2 CCDC88A PCOLCE2 HMGCR DYRK1A ALAS1 ACER3 KIAA0355 LACTB ENTPD1 RAP1A ZDHHC2 RANBP9 ZBTB21 CAV2 PAG1 TMEM38B RAB14 LIMS1 HAUS2 FBXL3 SEC24B C9orf72 GSDMA CD302 CCND2 TBX5 CA1 AFF1 EFR3A VPS37A PLGLB1 RAB8B MN1 MSRB3 DNAJA1 RABGAP1 FERMT2 SNX1 FAM177A1 PREX2 NAA30 TSPYL1 PXK WDR7 CELF2 BLOC1S6 MORF4L1 GPRIN3 YTHDF3 TSHZ3 KHDRBS1 PIK3C3 GNB4 ANKRD12 MBNL1 HELZ PITPNA CTTNBP2NL DCTN4 DIXDC1 PTCH1 COMMD8 ING2 FNIP2	down	*
MIR651_3P	0.0003525	0.0055960	0.4984931	-0.2138378	-1.325117	674	WEE1 RTKN2 SEMA6A COL25A1 SOSTDC1 USP12 GPIHBP1 ZC3H12C LRRC8C ATXN3 PRKG2 ADCY9 PTP4A2 EMP2 KCTD9 PTPRB TMEM170B CAV1 CORO1C QKI TMEM138 BMPR2 TBXA2R KCNN3 IL1RN C3orf70 OTUD4 CBL TMX4 ZEB2 UBL3 LATS2 SDE2 PICALM NLK REV3L FOXP1 HIPK3 PAQR3 KLF6 GLS CAMTA1 SLC7A11 GPBP1L1 SERPINB9 FAM122A TRAF6 AKT3 TMEM41B EPM2AIP1 ZYG11B FBXO8 FBXL5 SLC7A2 TAPT1 AMOTL1 FOXO1 SORBS1 AFAP1L1 RUNX1T1 RRM2B ANKRD10 BCHE KLF7 FBXL3 SPAG9 MGAT4A CADM1 HNRNPUL2 PAPSS1 UBE2B PIK3C2A CPT1A N4BP2L1 DSE TBX5 SLC6A6 N4BP1 KIAA0408 PDE1C AFF1 NCKAP5 IKZF5 CMTM6 EFR3A CNOT6L ACTR2 PIAS1 STK24 HGSNAT LIN54 FOXN3 ZNF426 LACC1 RBPJ DCP1A DDX60L RYBP PHTF2 RNF141 RAB8B SRSF3 ETV3 MITF HMBOX1 SLC14A1 ZFP91 CELF1 MN1 DDX17 MAP4K4 CNTN4 FBXO11 ATXN1L ENPP4 EEA1 GLIPR1 HSPA13 PRKCE IDS RC3H1 FSD1L LPCAT2 TRAK2 CXCL5 PREX2 NAA30 ZNF407 POGLUT1 SLC25A24 SPRY4 PELI1 CD164 PTP4A1 AZI2 USP7 ATG3 PBRM1 HNRNPA2B1 NR2C1 ZBTB1 BAZ2B HECW1 MTMR2 ATP6V1A GALC MAP3K2 PPP3R1 APLP2 TAGAP NPTN RIMKLB ARPP19 INO80D RNF2 C3orf38 INTS6 SF1 ALDH1B1 CDC42EP3 TAB2 ARIH1 ITGAE ALDH6A1 IPO5 FBXO25 BRWD1 ZDHHC21 SSH2 SOAT1 NHLRC3 CUL3 BCAT1 TTC28 EDN1 NALCN RNF38 SCAI PTEN FAM126B SYNPO2L RORA ITCH NRP2 NABP1 MAPKAP1 EHD4	down	**
MIR6835_3P	0.0022841	0.0236944	0.4317077	-0.2299758	-1.325071	368	ATXN3 RDX RAB3C RCOR1 FYN OTUD1 QKI BMPR2 PRKAR1A KCNN3 AGPAT4 CIT TMX4 ARHGAP29 SSTR1 ATP2B1 DNAJC3 FOXA2 HECW2 LIFR PPP1R15B RAB33B GLS GPBP1L1 ZNF697 ADIPOR1 CLN5 TMEM123 SETD3 PDGFA EXOSC9 PRDM16 C14orf132 BIRC2 ZSWIM6 ADO REST PLEKHM3 ZNF24 UBQLN1 DOCK9 RBMS1 NR1D2 CTBS ACTR3 ELMSAN1 N4BP2L1 PPP2R5A CLIP4 PDE1C BACE1 SEC31A EFR3A RAB6A SNX3 KCNA5 RBPJ HSD17B13 NEK7 PLEKHA3 PPP6C CNTN3 TMTC1 LIMD1 ETS1 DDX17 UHRF2 RCAN1 MCM9 PIK3R1 CREB1 SLC10A7 GFPT2 MORF4L1 SRSF6 TTBK2 PBRM1 PHF3 CCP110 MAP3K2 HNRNPH3 MYOCD KAT2B FKBP1A OPN3 SCN7A MTO1 THAP6 GPD1L RBMS3 OSER1 TTC28 RNF38 DNAJB9 SYNPO2L KIF1B RORA DOCK4 C1orf52 SLC44A5 MED17 RABGEF1 SUGT1 MAPK1 EIF3L SH3GLB1 ATP1B1 CSNK1G3 BSG LMO7 FAM160B1 MTSS1 SCAF11 CAPZA1 GABPB1 PCDH15 FAM218A CNTN1 WDR26	down	*
MIR147B_5P	0.0054626	0.0455776	0.4070179	-0.2380922	-1.324938	269	KMO GPR15 ZC3H12C PRKG2 EMP2 ZBTB34 OTUD1 TXNL1 OTUD4 PDCL LACTB PTPRM RANBP9 PLXNA4 PDE4D TCF7L2 HERC3 FBXL5 EIF1B EVI2B AGO3 SETD9 TNFSF15 ARNTL FBXL3 ATP6V0D2 MBD2 ZNF706 PDE1C AKIRIN1 CDKN2AIP PI4K2A CNRIP1 LIN7A AFF3 C2orf69 NRROS MYLIP FMNL2 DCP1A DDHD1 EBAG9 TIGD3 MAGI2 UTRN APBB2 TBC1D12 SP3 RBM22 TNFRSF9 ZNF407 ADNP2 CACYBP CD164 FXYD6 SRSF4 NFYC NPTN CLASP2 RIMKLB KAT2B EMC4 INO80D ARAP2 MOB3B SESN1 CPQ TXNDC15 CEP170 ALDH1B1 VPS4B MEX3C G3BP2 RBMS3 RNF38 ANXA11 RORA NAA15	down	*
RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP	0.0030210	0.0293096	0.4317077	-0.2344187	-1.324866	302	RAB11FIP1 ACP5 KMO SC5D IL1A DCSTAMP RDX DPYSL2 FCER1A ST3GAL6 ALAS1 CD9 GAS6 RFTN1 GM2A CSRP1 CYB5A TNIP3 HSPB1 LITAF ABCG1 GLS SLC7A11 STOM AKT3 ZFYVE16 TFRC TXN ATP6V1H APOC1 CD58 EPB41L2 CCNI IL10 CCL22 KCNMA1 ACSL3 CDKN1A CDS2 CCSER2 INHBA MATK N4BP1 TBC1D4 CRIM1 BTG1 ARL6IP5 CD80 PKNOX1 RAB8B PDCD6IP VAT1 LTBP2 MAP4K4 DUOX1 RABGAP1 JAK1 CCR7 CD83 CELF2 MOB1A SLC3A2 POGLUT1 GRSF1 RUNX3 DUSP5 CD86 DYNC1LI1 CD81 KYNU TNFAIP8 IER5 ATP9B CXCR4 TRAF1 PLGRKT NEK3 CD1E FOXJ2 CYTH1 LDLR DOCK4 CREG1	down	*
MIR182_5P	0.0012382	0.0149859	0.4550599	-0.2236520	-1.324492	468	EPAS1 RTKN2 COL25A1 EDNRB KLF13 ZC3H12C INSIG1 TMEM170B AATK TXNL1 BAG4 CORO1C VAT1L CITED2 AQP9 QKI ELMO1 MOB1B RFTN1 ACER3 TEX2 WWC2 SLC44A2 SLC2A14 HBEGF TACC1 RAPGEF4 EIF5 SPIRE1 CAMTA1 ZNF697 SLAIN2 PPP3CA FAM122A TNS1 PPP1R13B ARHGEF2 TAPT1 PRDM16 DENND6A LIMS1 SETD9 ZFAND5 THBS1 CEBPA MYRIP SPAG9 DOCK9 GPR85 SHC4 RECK RNF139 CCDC59 CUL5 GNAQ ZNF706 N4BP1 UBASH3B PAFAH1B1 TLL1 ACTR2 FOXN3 TOPORS SPIN1 VAMP3 CCNY MED28 APPL1 MITF SH3BP5 MAP4K4 SHOC2 FOXN2 RHOJ TBC1D12 SKIL SP3 PIK3R1 MBNL2 PRKCE GRB2 FAM43A CREB1 STX5 NUDT15 CGGBP1 PPM1F SPRY4 CD164 FOXO3 SRSF6 PIK3AP1 PDS5B ABHD13 CBFA2T3 RELL1 PPP3R1 TOB1 NRN1 PCCA INO80D INTS6 TNFAIP8 RTN4 JMJD1C B3GNT2 FAM126B MMD PAIP2 ANXA11 CAMSAP2 C21orf91 DAZAP2 DOCK4 GSPT1 SLC44A5 RAB2A EVI5 SPATA13 REEP1 SETX KLF15	down	*
ID1_TARGET_GENES	0.0003376	0.0053834	0.4984931	0.2595303	1.324283	998	HS3ST1 HOXB-AS3 CEP89 TICRR GPT2 ASCL5 CHEK2 PDCD6 ABCA17P CCDC127 NPAS1 TTF2 GCNT3 NUDCD3 NDC80 PLEKHA6 NMNAT3 IFI27L1 CDK4 IFT122 TOMM34 TPX2 GAPDH PLEKHA7 C19orf57 HNF4G MARVELD3 CAND1 AP1G2 KAZALD1 DNAI1 SIPA1L3 PPP1R9A SMARCD3 EXO1 C19orf48 DLG1 SMARCC1 XPNPEP3 ANKUB1 SDHA RPAP1 ZFYVE27 DCBLD2 F2RL1 STAP2 TP53BP1 PCCB TSGA10 TIGD4 FANCA BRAT1 CCDC77 FBF1 SPTB THBS4 C1orf226 POLD2 GTPBP3 TMEM132A LARS2 TPR ASCC2 HOXC6 ZNHIT6 EIF2AK1 LMNB1 LINC00511 MCCC2 TRIM11 PFN2 AP1M2 POLR3C LINC00265 ZNF786 PIH1D1 ABCB9 BRIP1 DDR1 RABEP2 BLM SLC18B1 RNASEH2B-AS1 LTB4R C2CD3 C4orf47 SLC25A10 GEMIN4 INCENP THOP1 GCKR TMED3 RASSF6 FAHD2A SUPT5H ANAPC5 CTDSP2 SSBP1 EXOSC2 CENPJ FAM135A AP3D1 C1orf112 XRRA1 SUN1 RBCK1 TCF20 KCTD13 SMG9 MRPL17 PMEL PODNL1 LARP1 PDK1 ANAPC7 TSPAN31 ZNF775 MTBP SNRPE GOLGA5 CBX1 CCDC57 PA2G4 IRF6 DHX34 MPI DNMT1 UPP2 CEP63 TAPBP TBC1D9B RHOC UQCRFS1 VIPAS39 SLC35C2 DCAKD WDR53 FAM47E-STBD1 FOXRED1 GSS SNRPA MNS1 AARSD1 MBD4 DHRS4-AS1 S100A16 LONP1 CCDC151 KIF22 GPRC5C EPHB2 TIGD6 DUSP12 MORN2 RHBDD3 MLEC CSNK1G1 MGMT SOX2-OT LMTK2 OS9 CCDC146 MRPL4 PKP4 ACAD10 SLC22A23 TRIM32 CCDC51 C15orf41 CKMT2-AS1 SYNGAP1 CDK13 NUP85 ZBTB45 ENC1 TMEM232 ELAC2 NIF3L1 BCDIN3D-AS1 CCDC137 TNK1 EFCAB7 RGL4 MEI1 L3MBTL2 DGKA KIAA0100 MAN2A1 TTLL3 DUS1L TCTN1 NRXN2 FITM2 PHYKPL CLINT1 KRT8 MGME1 PLEK2 MYO5C EML6 RAI14 CENPT NSUN6 DHX8 NOSIP BSN LRRC17 HEATR1 ADD3 EFHB TMUB1 AATF CLDN16 KATNB1 DNAJC21 RTKN PDIA4 SUGP1 RRP36 SH3TC2 U2AF2 MST1P2 NUP62 LRRC14 SPAG4 AMN1 BCL9 MCRS1 GLIS3 PRR11 PRDM10 NFRKB CISD3 ZNF70 DDX54 SNRPD2 DENR MRPL55 TXNL4B GTPBP2 ABCF2 ACKR2 ABHD10 BMS1 TNKS1BP1 CAPN10 TPGS2 PPP6R2 ZNF217 SAMD4B SRP9 SNRNP70 SNRNP200 RPRD2 FAM118B LINC00240 NDUFS8 POMK METAP1D DIP2B ALKBH6 UQCRQ ZNF131 CIAPIN1 SMC2 BCAS3 B4GALNT3 RPN1 MAU2 ALG1 NMT1 PAICS FIS1 CHERP FBXO34 RANBP3 MRPS27 SLC36A1 CYSTM1 FBXO45 ANKRD46 SFXN5 ZMYND10 RAD1 CCDC91 RNF32 RABL6 NLGN1 TTLL5 TRUB2 ILVBL CALU MOK DDX41 BRIX1 ATP6V1E2 FAM219A TRPC4AP PPP1R16A NCAPH SLC33A1 CYHR1 RNF14 TPM1 MEIS3 FAM47E SUMF2 DAZAP1 TMEM62 CEP290 APEH METTL18 HEXIM2 FGFBP3 DHX57 ARMC2 KLK10 TNFRSF1A ZDHHC13 MAN2C1 KLHL42 C4orf48 TRIM52 AKAP9 NIT1 PARL CNKSR1 RPL36 ZC3HC1 LPCAT1 FOXP2 USP35 GGA1 KTN1-AS1 EDC4 TOMM40 MECOM MCEE NHP2 STARD10 CCS RAG1 NPM1 IMP4 TEFM MSH6 RNF40 ZNF425 KCNK1	up	**
ZNF10_TARGET_GENES	0.0025469	0.0257471	0.4317077	0.2632514	1.322511	633	PTGES MEGF10 DDX12P CEP89 CHEK2 C1RL-AS1 ABCA17P DROSHA FBXO27 PDCD2L CYP2J2 SEMA4B TTF2 METTL1 ZFHX2 EFNA3 C4orf50 ZNF285 FLAD1 SEC14L5 ACAD9 WDR70 ZNF714 GOLGB1 KCNT1 ARHGAP33 GRHL3 FBXL19-AS1 ZFP64 TNC NUB1 KAZALD1 WDR62 DYRK1B CEP55 BBS1 STAP2 FBXW9 POLA2 GTPBP3 IRF3 MCM7 ADAMTS13 EFCAB12 CCDC114 DCDC2 FANCD2 GPSM2 SEC61A1 TARS2 POLR3C SLC9A3R1 SCAMP5 THAP10 MST1R RABEP2 FBXL19 MTG1 PHB ALDOA OSBPL7 COQ9 DHRS13 PARP1 ZNF229 NCAPG2 CMAS SSBP1 KCTD7 GOT2 ACP6 STX18 REEP6 TRIM2 PSMB5 STAT2 SEC61G PMEL FAM98C KRBA1 TMEM79 CCDC57 MAD2L2 VPS72 ANXA2R ZNF500 CHCHD3 CAPS2 ILF2 DLGAP5 PDCD11 IGLV6-57 SMG5 NDUFA11 PSMA5 ZNF133 EFCAB2 SNRPA MC1R OSBPL3 KIF22 ROGDI UBE2Q1 PCSK4 SCN8A JMJD4 ATG9B HIP1R TJAP1 AGPAT5 ITFG2 TCEA1 SPAG1 STX18-AS1 KIF20B DLK2 TMEM186 ASNS TM9SF4 NTN3 BCL2L12 CHD5 FAM200A CCDC159 POLB ENC1 PPIEL EFCAB7 LIMA1 GOLM1 UBE2O PPHLN1 TUBG2 ASB6 TCTN1 ASCC1 UBXN6 CDR2 ABCA7 ARVCF KDM4B ZNF160 PPCDC CYP2S1 LPCAT4 HHLA3 ANKRA2 SNAP47 C5orf22 TBC1D16 PRSS16 CREB3L2 TTLL6 SMARCC2 TCHP GOSR2 PRPF18 CAPN15 RPS26 ANAPC2 CCDC167 PAK4 STAT6 HOOK2 ARRDC1 ZNF292 ERGIC1 ZNF217 TEPP MICU1 TMEM101 PTPRF SNORA14B TBCB CASC2 ALKBH6 SLC12A2 ZNF131 CIAPIN1 TARBP2 SYNRG CENPE FZD3 POP4	up	*
U2AF2_TARGET_GENES	0.0006382	0.0089952	0.4772708	0.2594028	1.320056	884	PPM1H PRLR SPICE1 WFDC3 DNAH2 GMDS RPGRIP1L PDCD6 ZNF84 XYLB CCDC34 APOLD1 IQCE TTF2 CCDC113 BRCA1 CREB3L4 FANK1 CDK4 IFT122 DBF4B AP1S1 NUF2 ALDH18A1 WDR70 NBR2 KNOP1 NOX5 EIF3B ZFP64 COX11 C6orf132 TOP3B WDR62 RSPH1 NEURL2 BBS1 RND2 SPAG16 DPY19L2P2 TP53BP1 FOXJ1 AP4M1 TIGD4 CCDC13 CCDC77 BPHL AGT CBX3 C20orf96 ODF2 YKT6 LARS2 MCM7 DPCD SPEF2 RNF157-AS1 EFCAB12 GCAT SETDB1 NME9 ENTPD6 WDR73 GPSM2 PLTP C7orf57 TARS2 BCL2L2-PABPN1 C7orf50 THAP10 DNAAF3 SNAPC4 COMMD4 SYMPK STXBP4 ENTPD5 TRIT1 PES1 NRTN POLN EXOC3L4 NRSN2 KIAA0556 C2orf50 LRGUK LRRC6 CDK1 DNTTIP1 SSUH2 PICK1 TTLL9 WDR54 KIAA0753 AAGAB REEP6 ZNF815P CCNJL TMEM8B LRRC9 TCTN2 ENPP3 ZNF584 KLHDC9 POLR1C ZNF775 TNPO2 TTC23L TAF6 THAP8 SF3B3 KIAA1211L LRRC56 CCDC57 ZNF827 VPS72 TMEM231 CASC1 ZNF324B KPNB1 CHCHD3 NET1 CATSPERG TBC1D9B NPHP1 C19orf44 SLC35C2 SATB2 NEK10 DNAH7 TSNAXIP1 ADAT1 MNS1 MAN1B1 POLL MBD4 RAD9A YIPF3 GALNS GPRC5C CCDC130 SUDS3 MORN2 COPS7B UBE2Q1 PCSK4 NFATC4 COLEC11 MLEC IQCK FZR1 MAPK10 CLTA LAMTOR2 LIN37 ZSWIM1 TMEM186 COG4 FUCA2 IQCH SND1 C12orf73 CEP128 TYRO3 SCNN1G PLEKHB1 TRAF3IP1 NAIF1 ZBTB7B ATP13A1 SLX4IP GEMIN6 UBQLN4 EFCAB7 TMEM234 GTF3C1 UBE2O PSMB3 STOML2 CA11 CCDC30 EFHC1 ZNF497 ZNF76 UBXN6 PPP6R1 BAD KRT8 COMP ZNF432 MCM5 ANKS3 WDR35 SNRPD1 DYNC2H1 NEK4 ZNF599 FBXO36 NDUFS7 SLC1A5 PALM3 ZDHHC11 LHPP U2AF2 PATZ1 PRMT5 ARFGAP1 STRBP ZNF580 SPAG4 INTS8 PYCR1 GLO1 MAP3K14 GABPB1-AS1 MANBAL RFC5 CSNK1G2 DOHH YBX2 PAK4 CTU1 STAT6 CCDC181 BMS1 TRIP4 ZNF292 LRRC71 RUNDC1 METAP1D TBC1D32 UBAP2L CASC2 ZNF142 SYNRG TCF3 C1orf159 PFDN4 E4F1 RHPN1 DHRS3 LRSAM1 NMT1 TRUB1 SLC38A4 CYSTM1 RHPN1-AS1 GPN1 ARMC10 SLC39A1 DDB2 ZNF253 NLGN1 STK11IP PLXNB1 ATG4B PTPN13 MZF1 C12orf10 TRAPPC6A H1FX-AS1 NQO1 CNPY4 EIF2D STK33 DHX57 POLRMT DNAAF1 ZDHHC1 MED22 LUC7L3 PCGF2 SFXN2 DHDDS TEKT1 NSUN5 ITGB5 PDK2 POFUT2 HRAS ZNF649 RANBP10 GCC2 RPL36 PEX11A ZC3HC1	up	**
MIR302C_5P	0.0016395	0.0184231	0.4550599	-0.2223771	-1.319042	474	RTKN2 EDNRB ZC3H12C ST6GALNAC3 BMP2 COQ2 EMCN GPCPD1 SFR1 IDI1 NR3C1 PFDN1 RCHY1 TMX4 ZEB2 UBR3 KIAA0355 DNAJC3 B3GNT5 LIFR LATS2 BZW1 ECHDC1 PBX3 FZD4 SLC7A11 DACH1 SRSF2 HNRNPDL SPTBN1 ZFYVE16 ZEB1 TFRC ATP6V1B2 PRDM16 AMOTL1 NRARP MTMR6 ZCCHC24 REST TNFSF15 STK17B THBS1 MAP1LC3B ADAMTS9 SOCS5 FBXL3 NPR3 UBQLN1 PDE8A TADA2B ATP6V0D2 RECK UBE2B PIK3C2A CPT1A CUL5 LMBRD1 CNOT6L TGFB2 PDHX FLT1 CCNY PRDM11 ELF1 VPS37A LRRTM2 DDHD1 CTSS PHACTR2 RASSF10 NSMCE2 MSRB3 CYCS HSPA1B ARHGEF10 NXPE3 FOXN2 APBB2 PNPLA8 TTC14 FRYL OSM LPCAT2 GTDC1 TCP1 TSPYL1 CGGBP1 WDR7 CDK17 PTP4A1 RIN2 NAA16 IRF5 CHORDC1 NUP153 STRN SBF2 GNAI1 ATP6V1A NAB1 IRS2 MAP3K2 KANSL2 LTBP1 EMC4 MBNL1 INO80D HACE1 BMP2K RBL2 ANKLE2 RNF138 SESN1 CEP170 LRP12 CYB5R4 TAB2 TTLL7 PTCH1 BRWD1 ZDHHC21 CREBBP LYSMD3 EDN1 B3GNT2 FAM126B GTPBP8 RORA DOCK4 ZFPM2 SFPQ EIF4A2 SMAD4 MIER3 HNRNPH1 PSIP1 ACVR1C RBMXL1 CDKN1B SPPL2A	down	*
MIR3686	0.0036532	0.0338908	0.4317077	-0.2389265	-1.319012	275	TRIM71 ABHD5 SLC12A6 ZC3H12C BMP2 PPP4R1 RASAL2 QKI GAS6 EOGT ERG SH2B3 B3GNT5 MCTP1 CACNA2D2 ASAH1 GPBP1L1 SLAIN2 TCF7L2 CYP4V2 HIPK4 MCL1 PEG3 SETD9 FMO2 KLF9 CDK9 FMNL3 COTL1 RECK PEAK1 NCKAP5 MRVI1 LIN54 FOXN3 HAUS1 FMNL2 SYNPO2 PHACTR2 MAGI2 RAB8B TMTC1 C11orf58 EPC1 PNPLA8 PSTPIP2 MALT1 HOMER1 DENND4A EPPK1 DAGLA TMX3 ZFYVE9 IRS2 ACYP2 MICU3 ATAD2B ARAP2 DHRS12 UBE2D1 BRWD1 ZNF471 SSH2 PARVA NPAT GLUL LIMCH1 CECR2 PRKG1 MMD COL13A1 CNTNAP3B NAA15 LYZ ELP4 JDP2 FJX1 HMGCS1 PIP5KL1 SH3GLB1 PLXDC2 XPO7 XRN2 PPFIA1 WDR41 PIAS2 EXOC6 ESCO1 PYROXD1	down	*
MIR526B_3P	0.0007267	0.0099045	0.4772708	-0.2195955	-1.318871	526	RAB11FIP1 EREG TMEM100 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 RAB12 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 CDKN1A PDE3B NPAS3 NKIRAS1 UXS1 ELK3 WFS1 UTP23 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 JAK1 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 ARAP2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	**
AAGCACA_MIR218	0.0044518	0.0392395	0.4070179	-0.2303801	-1.318346	319	SLC24A4 SEMA6A SASH1 HMOX1 TRHDE KCTD9 CCDC88A RTN3 ELMO1 MKNK1 NR3C1 C3orf70 ZEB2 NUMB EDEM1 BRINP3 UBR3 NFIX TACC1 LIFR WNT2B FZD4 PEX5L PPP2R2A GPM6A FBXO8 ZMIZ1 MVB12B MAFG GAPVD1 SPAG9 SIK2 GPR85 SHC4 FRMD4A RNF139 WDR48 ADIPOR2 PPP2R5A OXSR1 GNAI2 AKIRIN1 PI4K2A FOXN3 RAB6A RPS6KA2 SERTAD2 SOCS3 MAGI2 RAB8B SEC14L1 ARL5B MITF VAT1 ZFP91 PIK3R1 MBNL2 PRKCE RAB8A ACSL1 PTP4A1 HIVEP2 PDE12 DUSP5 ZBTB11 GNAI1 KHDRBS1 DYNC1LI1 ATXN1 CSDE1 KCNA3 TOB1 MBNL1 DBNDD2 ARPP19 INTS6 WDR1 RTN4 SRP72 STAM2 HNRNPC CUL3 RET KIT RNF38 PRKG1 DLST SHISA6 PUM1 PURB BMI1 RAP1GAP MED17 PPP1CB ZFYVE26 JDP2 KALRN	down	*
NABA_MATRISOME_ASSOCIATED	0.0016938	0.0188204	0.4550599	-0.2217860	-1.318256	488	ANGPT4 SEMA6B SEMA3G CXCL3 CLEC1B SLPI SEMA6A EREG IL1A FCN1 FCN3 SFRP4 IL1B CLEC3B WNT4 CLEC12A BMP2 GPC5 BDNF EMCN CTSW CLEC12B CLEC10A FGF10 IL1RN IL23A SEMA6D BRINP3 ANXA1 CLCF1 BMP1 SEMA3B HBEGF ADAM17 WNT2B PLXNA2 CLEC7A MASP1 CLEC14A ANXA5 PRSS12 IFNK SERPINB9 PLXNA4 SFRP1 WNT3A ADAMTSL4 HPSE2 PDGFA NODAL CST3 IL10 MMP21 CCL22 CLEC1A TNFSF12 PSPN TNFSF15 ADAMTS9 CTSD ITIH5 CCL3 C1QTNF7 EPGN CXCL2 HPSE CCL4 SFTPD XCL2 INHBA CLEC9A ADAMTS8 C1QTNF2 INSL6 HTRA4 IL24 ANXA3 TLL1 TGFB2 MMP19 WNT9A IL17D CNTF CPAMD8 AREG IL6 MUC3A CTSS ADAMTSL2 HCFC2 SERPINB8 C1QA DHH ZFP91 SFTPB CTSZ BMP3 CSTA CLEC17A OSM SERPINB6 CXCL5 FSTL3 EGLN2 LGALS2 CST7	down	*
GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION	0.0016689	0.0186406	0.4550599	-0.2254541	-1.318012	420	RTKN2 SEMA6A WTIP OTUD7A DLC1 RASIP1 IL1B FBP1 CD44 CGNL1 INPP5K CAV1 MYADM TBC1D7 PLEKHA1 HMGCR DYRK1A USP47 CD22 HEG1 PPM1N RHOA PDE2A WWC2 MIR146A MYOZ1 SH2B3 TNIP3 HSPB1 RANBP9 RNF125 LITAF HIPK3 PAQR3 ADIPOR1 SIRPA NFE2L2 SFRP1 SPRY2 ARHGEF2 MAPK8IP1 PDE4D MCL1 ARRB1 SNAI1 DUSP3 FOXO1 YBX3 KLF4 PLAUR RRM2B THBS1 ARNTL EPM2A PDE3B PTPRC ATF3 TLR4 UBE2B TAF9 PER1 DUSP1 PLEK PINK1 PPP2R5C WFS1 PAFAH1B1 GNAI2 CALM2 MARK3 TGFB2 KANK1 PPP2CA RNF149 MAGI2 SEC14L1 LIMD1 ADRA1A CARD8 DNAJA1 DUSP8 RCAN1 RAPGEF1 GSTO1 BAG5 ACKR3 RASSF2 RRN3 SPRY4 CALM1 PKD2 CD74 PPP2CB TIMP2 KCTD10 NLRP6 DUSP5 SOD2 RGS2 PHLPP2 SESN1 ABL2 ARRB2 TPT1 PP2D1 NLRP3 GPD1L EPHA2 ING2 CUL3 TIMP3 SCAI FNIP2 PTEN DUSP7 RORA ITCH MAPKAP1 SMAD4 BANK1 SMPD1 HERPUD1 HTRA2 CHP1 UBR2	down	*
GO_RECEPTOR_REGULATOR_ACTIVITY	0.0034103	0.0322721	0.4317077	-0.2388984	-1.317681	288	ANGPT4 SEMA6B SEMA3G CXCL3 SEMA6A EREG IL1A CXCL16 ENDOU GPIHBP1 IL1B WNT4 GREM2 BMP2 KL PCSK9 BDNF CCL3L1 CLEC12B CDC42EP2 FGF10 IL1RN GAS6 IL23A SEMA6D CLCF1 BMP1 SEMA3B HBEGF MTRNR2L8 IFNK GRN WNT3A PDGFA NODAL IL10 MTRNR2L3 CCL22 TNFSF12 PSPN TNFSF15 CCL3 EPGN CXCL2 CCL4 XCL2 INHBA INSL6 IL24 TGFB2 GNRH1 WNT9A IL17D CNTF AREG IL6	down	*
MIR6504_3P	0.0040626	0.0366017	0.4070179	-0.2303782	-1.316725	328	CPEB2 SNX10 EMP2 ST6GALNAC3 PTPRB RASAL2 MS4A15 QKI BMPR2 TGFBR3 MOB1B RCHY1 CNST TRA2B RAB33B BZW1 NLK PRSS12 CAV2 SLC7A11 EIF4E LHX6 MPHOSPH6 SPTBN1 MAPK8IP1 PDE4D ROCK2 TLE4 FOXO1 PPP6R3 KLF4 ITM2B PEG3 HAUS2 PLEKHM3 ANKRD10 GAPVD1 CYP20A1 RECK UBE2B CAPZA2 CCSER2 PRICKLE2 IKZF5 SIAH1 TGFB2 METAP1 YBX1 SGK1 CTSS KIF13A PHACTR2 NEK7 INPP5B SH3BP5 CNTN4 EEA1 HSPA13 IDS CREB1 CTTNBP2 NECAB1 HIVEP2 MAPK8 NAA16 DCK PDS5B RSBN1L TMEM230 MYOCD RIMKLB KAT2B ABI3BP ATAD2B INO80D RNF138 ABL2 CTTNBP2NL SFT2D1 NT5C2 RAB5A TMOD2 ARIH1 PTCH1 PSME4 SRSF10 RASSF8 DOCK10 SCAI FAM126B CAMSAP2 CCND3 SHISA6 SPATA13 EIF4G2 ABI1 REEP1 PLAG1 PEX14 TBPL1 GJC1 NR4A2 MAPK1	down	*
GO_REGULATION_OF_DEVELOPMENTAL_GROWTH	0.0050172	0.0428944	0.4070179	-0.2383704	-1.316096	260	SLC6A4 TNR RBP4 SEMA6B SEMA3G SEMA6A DPYSL2 TRPV2 BDNF NEDD4L BMPR2 TGFBR3 TGFBR2 SEMA6D TBX2 WWC2 MYOZ1 SEMA3B CACNA2D2 TTL LATS2 HLX ADRB1 PLXNA4 ADRB2 ISLR2 NDEL1 SFRP1 WNT3A ITSN2 FOXC2 STAT5A TRIM46 YBX3 SOCS2 CDKN1A ZMPSTE24 TBX5 PAFAH1B1 RUFY3 MIR17HG SRF RBPJ NOTCH1 IFRD1 CREB1 RTN4R EPPK1 SAV1 PIM1 MEIS1 GATA6 MACF1 RGS2 PLAA IST1 FGF2 SEMA4A RTN4 CXCR4 PTCH1 ACACB ULK2 MBD5 STK4 SIN3A EDN1 PTEN FGFR1 MIR548C ZFPM2	down	*
MIR561_3P	0.0021885	0.0230066	0.4317077	-0.2253911	-1.315134	410	TBX3 ZC3H12C CPEB2 ATXN3 CLDND1 SH2D3C PTPMT1 RASAL2 BAIAP2 QKI YPEL5 ARL8B PRKAR1A VAPA TET2 CIT PDCL PPM1N ZEB2 ARHGAP29 UBR3 SLC36A4 FAM124A C1orf21 PBX3 ZNF503 SPIRE1 ZBTB21 PRSS12 PEX5L ZBTB8A HERC3 ZYG11B ROCK2 MTMR6 PTPN21 SORBS1 CASP1 SETD9 PRKD3 ID3 TJP1 FBXL3 SPAG9 NR1D2 CCL4 USP44 PTGER3 ZBTB43 SLC6A6 SPRYD7 CRIM1 CNOT6L ACTR2 ZDHHC20 PRKRA VPS37A PHTF2 DDHD1 EBF2 NEK7 RNF141 MAML2 PPA2 CPEB4 FERMT2 FYTTD1 IFRD1 PNPLA8 HSPA13 MBNL2 CREB1 RC3H1 FAM177A1 CGGBP1 CDK14 AGFG1 MBP PKD2 CCDC85A MYL12A BTBD7 ZFAND6 PPP2CB KIAA0232 ZBTB1 TEX14 ABHD13 IRS2 C16orf72 PCDH17 N4BP2L2 MICU3 ADAM10 CLEC2B MR1 ARPP19 CCNH PRDM8 INO80D SFT2D1 NBN ACAP2 LRP12 SEC61B ARIH1 ZNF471 KPNA4 CUL3 CCDC92 PAK2 RORA ZFPM2 WDFY3 NUP160 SLC35A1 ZBTB44 SNRPG	down	*
MIR548AN	0.0012371	0.0149806	0.4550599	-0.2256745	-1.314896	413	RAB11FIP1 PHACTR1 LRRC8C P2RY1 RDX SOX17 MTMR10 APIP VAPA FUCA1 TET2 CBL CIT PDE2A ATP2B1 MCTP1 FZD4 PPP3CA BAG1 ZYG11B AGO4 AGO3 LIMS1 PEG3 KLF7 FAM49B ATL3 RBMS1 NR1D2 NKIRAS1 VIM C9orf72 LBH PIK3C2A MBD2 KPNA3 CALM2 STK24 C2orf69 SACM1L SRF CLIC5 USP25 SERTAD2 UFM1 SPIN1 ARL6IP5 VAMP3 TMOD1 RAB8B ARL5B LRCH1 KCTD12 GLUD1 OSTM1 WTAP FERMT2 ATXN1L GRB2 ATL2 ZNRF3 TUBGCP3 TMEM128 BLOC1S6 AGFG1 YTHDF3 SRSF6 XYLT1 ING3 NUP153 PBRM1 TFEB HNRNPA2B1 STRN MAP3K2 PCDH17 PIM1 TMEM70 ANKRD12 GATA6 NRN1 PDE4B ETS2 ATAD2B INO80D ANKLE2 SCN7A EPN2 NSUN4 CREBBP SSH2 VSIG10 ING2 PAK2 B3GNT2 MTUS1 CECR2 FAM126B MMD FAM13B IQGAP1 EIF4A2 SMAD4 EVI5 MIER3 SPATA13 ZBTB44 PAPSS2 RABGEF1 FNBP1 REEP1 EGR1 CDON ENDOD1 USP30 SSB CLOCK ING1 MZT1 ITGB1 HP1BP3 PATL2 PRTG CD69	down	*
GO_IMMUNE_SYSTEM_DEVELOPMENT	0.0002458	0.0040956	0.4984931	-0.2064176	-1.313349	808	EPAS1 RTKN2 CLEC1B SWAP70 CD101 TEK ACE TAL1 KLF13 PPARG HHEX GATA2 SPN SNX10 DCSTAMP WNT4 OSCAR LYL1 PDE1B LMO2 TMOD3 SAMHD1 CITED2 EML1 FGF10 CDC42 TGFBR3 GAS6 TET2 PSMD5 TGFBR2 TRIB1 LILRB3 IL23A CD8A CASP9 RHOA ANXA1 SH2B3 CLCF1 FBXO7 ADA SBDS ADAM17 WNT2B RASGRP4 PICALM KLF10 FOXP1 KLF6 HLX MS4A1 IFNK ASH2L GATA3 JAM3 RB1 IL18R1 TRAF6 NFE2L2 SFRP1 WNT3A ZEB1 SPI1 TFRC ARL11 TIPARP FLI1 ZMIZ1 EVI2B IL10 AGO4 MMP21 NRARP AGO3 SLC46A2 KLF4 REST FUT7 THBS1 CEBPA SOCS5 MPL CCL3 PTPRC AXL KIRREL3 ID2 TLR4 FCER1G SMAD7 PLEK ZMPSTE24 LYAR INHBA IL7R UBASH3B CYP26B1 PAFAH1B1 HES1 MIR17HG ADD1 TGFB2 SRF NRROS NCKAP1L RBPJ IL17D CD80 IL6 WASF2 PKNOX1 PSEN1 JUN PSMA1 MITF NOTCH1 GABPA CUL4A ETS1 TYROBP HSPA1B JUNB OSTM1 DNASE2 PTGER4 CCR7 ATXN1L SP3 PIK3R1 PABPC4 CD83 IRF8 GPR183 CREB1 OSM MALT1 SIGLEC15 RC3H1 ZBTB24 AP3B1 FSTL3 TBX21 RASSF2 ZNF683 SNRK WDR7 CD34 PLCG2 FOS RRAS KLF2 CD164 AZI2 TNFSF13 PSMD12 RUNX3 FOXO3 TREX1 KAT8 CD74 CR1 CCR4 TGFB1 EPB42 CD1D ZBTB1 JMJD6 YTHDF2 CBFA2T3 CD86 PDCD1 PIM1 SLC8A3 CD81 LGALS3 MEIS1 CCR1 MFNG N4BP2L2 GPR18 KAT2B CCR6 IL18 WDR1 NBN SEMA4A CEBPD PIP4K2A CDKN1C MFAP5 DACT2 RIPK2 NLRP3 TOB2 CCR9 HAVCR2 PSME4 EPHA2 CREBBP CD19 STK4 SIN3A NFKBIA RET KIT DOCK10 CD3G ETV2 DNAJB9 TNFSF9 GPR171 RORA ITCH PSMD6	down	**
AAGCCAT_MIR135A_MIR135B	0.0036956	0.0341731	0.4317077	-0.2364178	-1.312972	287	BMPER BACH1 RASAL2 LONRF1 QKI BMPR2 MKNK1 RGPD5 C3orf70 MOB1B HPS5 SEMA6D LDLRAD2 BZW1 LINC00315 LCP1 GATA3 AKT3 ARHGEF2 HNRNPU ROCK2 FOXO1 KCNMA1 SDCBP PPP6R3 ADO KLF4 PRKD3 ADAMTS9 GRK5 ST7L GPR85 ATF3 CCND2 FRMD4A ELK3 INHBA PPP2R5C KPNA3 BACE1 CPLX1 NCOA1 SIAH1 FOXN3 TOPORS SERTAD2 PHTF2 WSCD2 KCTD12 SP3 FBXL16 ENTPD4 SNRK GPR3 CTTNBP2 PELI1 YTHDF3 SLC35F1 EPHA3 NUP153 DUSP5 CNTNAP1 PGGT1B PHLPP2 RNF138 ZNF143 FKBP1A TRAPPC8 BRWD1 PDE4A SKI MTUS1 PDE8B NR3C2 CREG1 TLK1 SHISA6 EVI5 MIER3 ZBTB44 PHOSPHO1 PSIP1 JDP2 KALRN ZNF385B DRAM2 ATP1B1 API5 TRPM7 WAC MTSS1 ZNF362 PDE7B MAN1A1	down	*
GO_OTHER_ORGANISM_PART	0.0017317	0.0191507	0.4550599	0.9990714	1.312418	1	LTF	up	*
GO_MOTOR_LEARNING	0.0025127	0.0255085	0.4317077	0.9987619	1.312011	1	DKK1	up	*
GO_VESICLE_MEMBRANE	0.0001710	0.0030137	0.5188481	-0.2154189	-1.311988	626	SIRPB1 RAB11FIP1 EREG OLR1 MCOLN1 PECAM1 HVCN1 CD55 WNT4 RAB44 CLEC12A IZUMO1 RAB3C PTPRB FOLR1 CD44 CAV1 VAMP2 C5AR1 MARCO MANBA VAPA CD9 LAMP1 SLC11A1 SCARF1 LILRB3 RHOA CD36 ANXA1 SLC44A2 MCTP1 HBEGF CD33 RILP RAP1A PICALM FZD4 SPIRE1 ANPEP CAV2 STOM LAIR1 SIRPA ADRB2 CD93 LAMTOR3 WNT3A TFRC RAB14 CD58 MSR1 FABP5 ARRB1 MPEG1 NOSTRIN BST1 PTAFR PLAUR DAB2 GAA STX3 ATP6V1D CLIC4 ABCC4 SEC24B TMBIM1 ITGAX PTPRC EPGN SELL SELP ATP6V0D2 M6PR CD53 FCER1G EPS15 WFS1 HTT VAMP5 IL7R PEF1 HLA-DQA1 DEGS1 ANXA3 BACE1 SEC31A CMTM6 HGSNAT RAB6A NCKAP1L TBC1D5 PRCP MYO1C VAMP3 AREG SAR1A PSEN1 PHACTR2 INPP5B SNAP23 APPL1 RAB8B PIKFYVE CYB5R1 NECAP1 SH3BP5 RAB31 USO1 RAC2 ATP6V0B TYROBP ATP11A RHOG RAPGEF1 ENPP4 GLIPR1 GRB2 RAB8A STX5 SERPINB6 GRIA1 UNC13B AP3B1 SNX22 GPRC5A SNX9 ATP6V0D1 UBB MFSD10 PKD2 ALDH3B1 CD74 CR1 SYPL2 MME SORT1 SIGLEC14 TMX3 AP1G1 DOK3 VAMP4 FPR2 TSPAN14 PIK3C3 DYNC1LI1 ATP6V0C GPR84 APLP2 LGALS3 GABARAPL1 BRI3 STX12 GPR18	down	**
GO_MITOCHONDRION	0.0003782	0.0059163	0.4984931	0.2554618	1.311866	1268	CPS1 PPM1H TP63 HKDC1 BBOX1 PTGES BIK HJURP AK4 CEP89 BDH1 GPT2 EYA2 CCNB1 GPAT2 FLVCR1 COA1 CHCHD6 DDIT4 TSFM SLC25A21 PIF1 NMNAT3 SORD IFI27L1 TBRG4 THEM4 CREB3L4 THEM5 MRPL46 ANKZF1 NIPSNAP1 MSTO1 NDUFS6 FLAD1 TOMM34 ACAD9 ALDH18A1 SFXN1 TFDP2 NNT PRKCA CYP27B1 TYMS GLDC TDRKH LIG3 COX6B2 SHMT2 MRPS35 COQ3 COX11 AGK UQCC1 TAMM41 NME1 IKBKE AARS2 CASP2 NOS1AP NDUFB8 NUDT1 CISD1 GOLPH3 XPNPEP3 SDHA QTRT1 MRPL15 PCCB CYP24A1 GPER1 BPHL NDUFS2 PSENEN TMEM177 YKT6 GTPBP3 LARS2 COASY GCAT AKAP1 AMACR ERAL1 MRPL3 PKM MRPL27 BLOC1S1 MCCC2 SOX4 PYCR2 TARS2 FAM162A LETMD1 LIG1 BRI3BP SARS2 HEBP2 ABCB6 ASS1 TRMT61B ACSF2 COX19 SLC25A39 DCTPP1 TIMM50 KCNJ11 MRPS11 PERP ETFA FDXR MRPS30 MTG1 PHB TST NOL3 ATAD3C IDH2 SLC25A10 UQCR11 COQ9 TRIT1 PARP1 THOP1 PON2 GCKR MRPL36 FASTK HARS2 URI1 MRPL37 PPM1E CDK1 SSBP1 PICK1 ATP2A1 CCM2 NUDT2 DMGDH GOT2 ZMIZ2 OAT E2F1 ACP6 UNG TRAP1 TMEM8B L2HGDH MCAT DNA2 DGAT2 MRPS2 SLC25A13 MRPL17 POU5F1B ACSBG2 PDK1 FEN1 MECR COA4 MRPS12 TNRC18 LIPT2 ETFB ATAD3A NLN UQCC2 CPT1B STK11 CHCHD3 NRGN ULK1 CHCHD2 HYKK MYO19 PARS2 FANCG IFI27L2 UQCRFS1 GNPAT DLGAP5 ATP7B NADK2 NDUFA11 NFS1 SPG7 COA3 FOXRED1 SPATA18 TRMU MTOR DNAJA3 PUS1 ALDH7A1 FHIT ADAM28 SLC25A18 UROS MRPS34 LONP1 DHODH PTGES2 C19orf12 MRPL11 MRPL52 COX7C PPOX DTYMK MSRB2 HIP1R MRPL4 ACAD10 AGPAT5 MAPK10 DAP3 ENOSF1 TMEM186 DNAJC11 NDUFA13 GFM2 GSTK1 GK5 ACSL6 JTB COX10 PARP9 NAIF1 ELAC2 NT5M YARS2 NIF3L1 DHTKD1 KLC2 CHPF P4HA1 NAGS C15orf62 TIMM13 BRD8 STOML2 IARS2 CHCHD1 SIRT4 GBF1 C12orf65 LRRC59 FAHD1 MRPS23 BCL2L1 BAD NAT8L NOL6 PHYKPL MRPL24 MGME1 MRPS33 CKMT2 MRPL28 MRPL41 HIBADH ROMO1 CAPRIN2 HEATR1 ACOT11 SIRT5 MALSU1 TFAP4 MRPL53 HAX1 PRODH CYP2D6 NDUFS7 AMT MRPL51 LRRK1 SUOX TCHP PLEKHN1 DOK7 NDUFV1 PYCR1 MRPL14 AGMAT ME1 SCO2 DCPS CISD3 ECH1 MLXIP VDAC1 MRPS25 PDF MRPL55 NME4 CDK5RAP1 ABHD10 UQCRC1 LPIN1 ACSF3 HK2 ANK2 RAD51 HLCS GADD45GIP1 CAPN10 NBR1 MTIF3 TOMM40L COX5B SLC25A29 ATG4D NOS1 MCU OXCT1 RSAD1 ECHS1 ZNF217 MRPL9 TRAK1 MRPL21 AIFM2 MICU1 NDUFA8 NDUFS8 RHOT2 METAP1D NUBPL CPOX ETHE1 AURKAIP1 VDAC3 UQCRQ CIAPIN1 PNKP CPT1C PARG XPC PFDN4 EARS2 MPG GLYCTK ZNF205 MTHFD1 TP53 NMT1 TRUB1 TIMM44 FIS1 APEX1 SYNE2 MRPS27 GPN1 PDP1 ARMC10 SFXN4 BCAT2 SFXN5 MRPL20 RIPK3 MRPL48 PI4KB NDUFB7 COX6B1 DNM1L TK2 MRPS26 IMMP2L GSDMC TRUB2 PLIN5 COX17 ACAD8 HEMK1 CYP11A1 MTG2 C12orf10 MAP2K2 ACSL5 CYB5B RPUSD3 TFB1M SARDH BCKDK TOMM7 RTN4IP1 NDUFAF6 POLRMT TNFRSF1A SFXN2 BMF MRPS16 ACSM3 UCP3 DGUOK SPHK2 TOP3A PDK2 GSK3A PPARGC1B PDZD8 MRPL12 CRAT NIT1 PARL GSTP1 CLPP SRI MRPL43 SDHAF1 FASTKD3 OPA1 RSAD2 BAK1 MRPL2 TOMM40 MCEE TIMM10 GLRX5 COQ5 MPST TEFM PGAM5 GCSH XAF1 MRPS6 DHRS4 D2HGDH DHX32 STXBP1 ABCD3 HINT2 MARS2 CS NDUFB2 TXN2 TPPP CMPK2 PC LRPPRC COX15 TIMM9 MCCC1 DYNLT1 PPP2R1A MTHFD2 BOLA3 CALM3 BNIP1 TMEM102 COX6A1 METTL17 SLC44A1 SLC25A35 FIBP COQ4 TFAP2C CAPN1 NDUFA4L2 TMEM14A BECN1 COA6 PNPLA7 MIEF1 NDRG4 ACOT7 COX6C ECHDC2 ABCB8 PTCD2 IDE NDUFA9 GRAMD4 SDHC RNASEL SLC27A1 WDR93 MRPS7 CHCHD5 ACADS MRPL35 MRPL13 DARS2 STPG1 TXNRD3 DHX30 GATM CLPB NOD2 PDSS2 CNR1 MRPL33 GCLC GSR DNAJC5 NDUFA10	up	**
MIR4262	0.0005710	0.0082063	0.4772708	-0.2128978	-1.311726	641	TRIM71 IL1A SGK3 ATXN3 ADCY9 MBOAT2 RAB3C OTUD1 SAMHD1 BAG4 QKI SRSF7 PAFAH1B2 S1PR1 TET2 OTUD4 EPB41L3 ZBTB2 TGFBR2 ACER3 ZEB2 ZBTB4 STARD4 ATP2B1 SH2B3 DNAJC3 UBL3 CHMP1B NAAA PBX3 NLK SPIRE1 FOXP1 HIPK3 KLF6 RNF182 GLS SLC7A11 MS4A1 SLAIN2 MED26 TMEM123 SLC25A37 TNS1 AKT3 TCF7L2 UBE2D3 TFRC ADARB1 AGO4 PER3 ADO SLC38A11 ZADH2 GAPVD1 NR1D2 TADA2B CD302 RECK ZBTB43 UBE2B ELMSAN1 DSE CUL5 PEAK1 BCLAF1 NUS1 TBC1D4 CRIM1 AKIRIN1 IKZF5 TLL1 CDKN2AIP PIAS1 C2orf69 SACM1L ZNF426 MTPN SERTAD2 KANK1 GPBP1 CREBRF METAP1 CDC40 PHTF2 COPS2 NEK7 PLEKHA3 RAB8B HECA PNMA2 CPEB4 ETS1 HRH1 ADRA1A PDE5A CNTN4 IPO7 LYRM1 PI4K2B MBNL2 FRYL CREB1 MORC3 FSD1L LPCAT2 SLC10A7 ZNF597 OGFRL1 RASSF2 EPC2 BLOC1S6 AGFG1 GPRIN3 SPRY4 CDK17 CALM1 NIPAL4 YTHDF3 ZFAND6 GOLGA8R AKIRIN2 AP1G1 PHF3 CCP110 BAZ2B ZNF844 GOLGA8H CBFA2T3 NAB1 LRRC32 IRS2 ZNF136 ATXN1 PPP3R1 GATA6 RIMKLB MICU3 KAT2B INO80D BMP2K RLF FKBP1A CTTNBP2NL MGAT2 PARM1 ACAP2 EPHA4 TAB2 SIK3 UBE2D1 TBC1D1 MEGF9 BRWD1 GPD1L G3BP2 TBCEL NPAT PKNOX2 LIMCH1 CUL3 RASSF8 TIMP3 FNIP2 CHCHD7 CECR2 FAM126B KIF1B CAMSAP2 RORA CNTNAP3B DOCK4 GRB10 PUM1 PURB MIER3 DMXL2 CBX7 SETX KLF15 PLAG1 CDON MB21D2 DUSP6 TBPL1 CLIP1 ZNF800 ADAMTSL1 ENDOD1 HIPK1 SSB MAMDC2 CCNK EYA3 ATP1B1 PPIP5K2 PRTG CD69 XPO7 PPFIA1 SPTY2D1 GOLGA8B PAX5 ZNF14 TSC22D2 RAD21 POLI	down	**
MARTINEZ_TP53_TARGETS_UP	0.0023665	0.0243619	0.4317077	-0.2201392	-1.311022	513	SLC6A4 GPD1 WEE1 EREG HSPB7 PECAM1 LRRC8C MNDA CAT USHBP1 EMP2 CYP4B1 LIPA RAMP2 ARRDC4 LPL CD44 BAG4 MSRA MEF2A ALAS1 NR3C1 TGFBR3 NCF2 FUCA1 TGFBR2 TRIB1 PILRA SPCS3 GINM1 TXNIP CD36 STARD4 CLCF1 BMP1 NDUFAF7 BZW1 PRELP RANBP9 NLK LITAF HDC ZNF410 HIPK3 CAV2 LCP1 SERPINB9 STOM PPP3CA NR4A1 SIRPA RGCC IL18R1 SPTBN1 SRGN TCAP UBE2D3 TFRC PDGFA HIF3A MSR1 CFD TNNC1 SORBS1 LIMS1 ST3GAL2 PEG3 PRKD3 DRAM1 THBS1 CLDN5 ITIH5 CDKN1A RBMS1 ATF3 CTBS CCND2 TM6SF1 DUSP1 ALOX5AP WDR48 PINK1 HLA-DQA1 ADD1 MAPRE2 TGFB2 ZNF330 SPIN1 RBP7 HCAR3 SAR1A NSMAF ESD RAB31 SLC14A1 TYROBP RABGAP1 JAK1 PRKCE MORC3 TPP2 IP6K1 CELF2 ACSL1 MOB1A FOS RRN3 UBB PNPLA2 KLB CD74 CPA3 SORT1 ZNF521 CHPT1 PEA15 ITGA9 SERPINB1 HBP1 GNA13 LTBP1 SERINC3 MR1 PCCA SOD3 ARPP19 RXRA CCL20 AMD1 PDLIM5 MGAT2 DCTN4 RTN4 PIP4K2A CDKN1C MFAP5 CALCOCO2 NSUN4 ACTB HAVCR2 PSME4 PLGRKT TMEM109	down	*
MIR1_3P	0.0053851	0.0451663	0.4070179	-0.2285994	-1.310746	322	TSPAN4 SOWAHC TBX3 TTC7B BDNF MMRN1 CORO1C CITED2 SLC25A30 NEDD9 CBL NFATC3 PFDN1 ZEB2 SEMA6D ZBTB4 TRA2B MCTP1 PICALM FOXP1 HIPK3 EIF4E DACH1 ASH2L PLXNA4 SFRP1 ANKRD29 HNRNPU FLI1 SLC7A2 CPED1 HMGN1 KLF4 THBS1 ZNF24 MGAT4A GPR85 PIK3C2A WDR48 PEAK1 NCOA1 C2orf69 NINJ1 SLC8A1 SLC25A25 ELF1 PDIK1L CREM UTRN LRCH1 HMBOX1 INMT ETS1 SNX2 DDX5 PRKCE MSANTD2 CAP1 SLC10A7 YWHAZ CEBPZ TAGLN2 CDK14 FOSB AZIN1 AP1G1 KCTD10 VAMP4 ATP6V1A NAB1 MYOCD ADPGK HACE1 RNF138 INTS6 CTTNBP2NL WDR1 SEC63 RAB5A METTL21A ACTB MEX3C TIMP3 EDN1 RNF38 MMD SAMSN1	down	*
GO_POSITIVE_REGULATION_OF_TRANSPORT	0.0001687	0.0029765	0.5188481	-0.2095448	-1.310671	766	SLC6A4 SIRPB1 RBP4 KMO CD300LF RAMP3 IL17RB IL1A STAC FCN1 EDNRB PPARG GATA2 SFRP4 IL1B F2RL3 SLC51B P2RY1 RDX PLA2G10 TRPV2 PCSK9 TRPC3 FYN LPL SHANK3 HCAR2 RGS9 INPP5K CAV1 NEDD4L VAMP2 ADCYAP1R1 MEF2A CDC42 IL1RL1 GAS6 LAMP1 CBL CYP4A11 SLC11A1 SCN5A ABCB1 FGR EDEM1 CD36 JPH2 ANXA1 CNST ATP2B1 CD33 RAP1A CLEC7A ABCG1 PTX3 STOM GATA3 PPP3CA SIRPA RGCC ADRB2 NFE2L2 SPTBN1 PPP1R13B CRTAM WNT3A MAPK8IP1 TCF7L2 UBE2D3 CD58 PPP3CC IL10 ARRB1 PPT1 SCP2 SDCBP SORBS1 CASP1 TRIM46 TACR2 ACSL3 PTAFR DAB2 MYRIP CCL3 CADM1 P2RY2 PTPRC KCNMB1 AXL CCL4 TLR4 ARC FRMD4A SFTPD FCER1G LYAR INHBA CLEC9A ADIPOR2 PINK1 WFS1 HTT GNAI2 RUFY3 TP53BP2 CALM2 TGFB2 NCKAP1L TBC1D5 MYO1C SCN4B IL6 SAR1A CD160 SGK1 CTSS PSEN1 IL2RB APPL1 MAGI2 RAB8B PDCD6IP RAB31 GLUD1 RAC2 CARD8 PLK3 IFNGR1 RAPGEF1 GSTO1 PTGER4 PIK3R1 PRKCE CREB1 OSM NPR1 UNC13B RBM22 PRKACA HOMER1 YWHAZ CD34 PLCG2 CD151 RHOQ CALM1 MBP EHD2 PKD2 MAPK8 CHIA AZIN1 TGFB1 EHD1 PARD6A AP1G1 FPR2 MTMR2 KHDRBS1 APBB1 IRS2 PPP3R1 CD81 LGALS3 EXOC1 ORM2 CCR1 CLASP2 ACTN2 PLAA CSNK2A2 PPID TSPO ARPP19 UNC13D HSPA2 PCM1 ARRB2 RAB5A VPS4B RIPK2 NLRP3 PTCH1 ACTB HAVCR2 IPO5 GPD1L HNRNPK BOK CD19 SREBF2 GLUL NFKBIA RAPGEF3 ADORA2A RAB2B EDN1	down	**
GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS	0.0051786	0.0439668	0.4070179	-0.2264670	-1.310474	366	GPD1 TRIM71 HMOX1 ABHD5 IL1B ATXN3 RDX PCSK9 ECSCR SOX17 CAV1 NEDD4L PAFAH1B2 TRIB1 RCHY1 EDEM1 FBXO7 RILP HECW2 BTG2 RNF144B FAM122A ADRB2 NFE2L2 ZYG11B TIPARP FBXL5 ROCK2 RAB12 FOXO1 MEFV TNFSF12 RNFT1 ROCK1 DAB2 CEBPA SOCS5 EPM2A UBQLN1 ATG7 C9orf72 RNF139 SMAD7 CPT1A PINK1 HTT C4BPB CNOT6L PIAS1 MYLIP IL6 PSEN1 NKD2 HSPA1B PLK3 PRKCE STX5 RC3H1 SNX1 UVRAG EGLN2 RALB SNX9 GRSF1 PNPLA2 YTHDF3 FOXO3 HNRNPD TFEB SMCR8 METTL14 HECW1 YTHDF2 CBFA2T3 ZC3H12D IRS2 CNOT7 CD81 BAG6 TOB1 HACE1 BNIP3L SESN1 PIP4K2A HSP90AA1 CALCOCO2 RIPK2 ARIH1 ULK2 DAPK1 CTSC PTEN ITCH LDLR CNOT8 ZFAND2A PUM1	down	*
GO_POSITIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS	0.0001004	0.0019434	0.5384341	-0.2068123	-1.310345	885	GPD1 FFAR4 ANGPT4 DAB1 HCRTR1 EREG RAMP3 ACVRL1 IL1A SASH1 TEK ACE DLC1 EDNRB SCIMP TAL1 PECAM1 ADTRP GLIPR2 IL1B LHCGR ADCY9 P2RY1 EMP2 ADCY4 RAPGEF2 BMPER PID1 BMP2 CDH5 ENG KL BDNF FYN SH2D3C CD44 CCL3L1 CCDC88A BAG4 CAV1 BMPR2 ADCYAP1R1 C5AR1 HMGCR FGF10 PRKAR1A CDC42 MIR27B MARCO NEDD9 IL1RN GAS6 SLC11A1 TGFBR2 MOB1B IL23A FGR RHOA ZEB2 AVPI1 CD36 CLCF1 HBEGF CD33 ADAM17 RAP1A PPP1R15B ITGA5 MAP3K8 FZD4 CAV2 CAMTA1 IFNK RGCC ADRB2 TRAF6 LAMTOR3 CRK SPRY2 WNT3A ARHGEF2 MAPK8IP1 TXN PDGFA NODAL SORBS3 LRP4 MAP2K3 ROCK2 ARRB1 CCL22 SDCBP NPNT ACSL3 PTAFR PLAUR ROCK1 DAB2 TNFSF15 THBS1 CDK9 SPAG9 PDE8A CCL3 CDKN1A PTPRC EPGN IRAK2 KCTD20 CCL4 TLR4 MIR24-2 CCND2 XCL2 PLEK INHBA PINK1 PPP2R5A OXSR1 PIK3R5 GNAI2 HES1 CALM2 IL24 PTH1R TGFB2 STK24 NCKAP1L ARL6IP5 CD80 CNTF PPP2CA FLT1 CCNY ADCY2 AREG IL6 DNAJC27 BCAR3 PSEN1 SOCS3 MAGI2 JUN NOTCH1 ZFP91 HRH1 ADRA1A PDE5A BMP3 MAP4K4 MTMR9 PPP1R15A RAPGEF1 CCR7 ACKR3 PRKCE GPR183 OSM MALT1 PRKACA TNFRSF10B RASSF2 GPRC5A RALB NDST1 FGFR4 ACSL1 GPR37L1 SNX9 UBB CALM1 KLB PKD2 CD74 WNT11 TIMP2 TGFB1 VAV3 PEA15 TEC FPR2 MIR23A SH3RF3 DUSP5 MAP3K2 RELL1 TERF2IP CD81 NQO2 CCR1 NPTN CCL20 ICAM1 ANKLE2 HSPA2 FGF2 IL18 NEK1 LAT NBN ARRB2 TIAM1 CXCR4 HSP90AA1 EPHA4 TAB2 RIPK2 HAVCR2 ISCU MAP3K4 CD19 LIMCH1 STK4 RET COPS8 RAPGEF3 KIT EDN1 PAK2 FNIP2 PTEN DUSP7 MMD FGFR1 DAZAP2 NRG1 CCND3 IQGAP1 MAPKAP1 EHD4 SMAD4 BANK1 FLT4 SMPD1 SPHK1 CSF2 ABI1 UBE2V1 EGR1 PPP2R3C GREM1 CDON C5AR2 GHR CDKN1B DUSP6	down	**
MIR3133	0.0011541	0.0142137	0.4550599	-0.2248988	-1.309952	417	AKAP5 LPIN2 EDNRB TMEM170B HSD17B11 QKI HMGCR RGPD5 VAPA OTUD4 CBL MOB1B ZEB2 EDEM1 KIAA0355 NCEH1 LACTB SLC2A14 SLC36A4 HECW2 LATS2 MTF1 ZNF503 HIPK3 RNF182 CAMTA1 PAG1 DACH1 MED26 TFEC MYCT1 PDGFA FLI1 CYBRD1 TAPT1 CCDC82 PPM1K LIN7C PEG3 RUNX1T1 FMO2 TJP1 STK17B KLF7 ZNF24 ITIH5 ATL3 MGAT4A CADM1 CXXC4 ACTR3 PTGER3 CUL5 SLC25A32 ZNF706 RUFY3 LIN7A TGFB2 LIN54 USP25 CREBRF TMOD1 PDIK1L SYNPO2 NEK7 SRSF3 NECAP1 TMTC1 MITF DHX15 PCGF5 FSD1L ZNRF3 NAA30 RGS13 DENND4A MOB1A NECAB1 HIVEP2 PKD2 PPTC7 TRAPPC10 NAA16 CR1 SORT1 NIPA2 ATG2B TEX30 GNAI1 MAP3K2 C8orf37 INO80D RNF2 ARAP2 CEP170 SCN7A PARM1 TRAPPC8 ARIH1 TDRP IPO5 PSME4 ZDHHC21 CREBBP SRSF10 KLLN CUL3 BCAT1 CEPT1 SCAI EPB41L4A FOXJ2 DUSP7 DNAJB9 PRKG1 CAMSAP2 C21orf91 RORA	down	*
ELF2_TARGET_GENES	0.0028183	0.0277229	0.4317077	0.2592448	1.309852	694	RUVBL1 CEP89 COIL NUDCD3 PHF14 SRGAP3 TBRG4 THEM4 METTL1 GTSE1 KIF14 SNF8 STIL FLAD1 COPB2 GON4L MCM8 RCCD1 NCAPD2 SMUG1 ZNF107 UQCC1 LSM5 GOLPH3L RAB11B-AS1 RPAP1 COPG1 WASF1 FBXW9 TIGD4 EXOC4 RPL32P3 CCT5 CENPL EME1 NUP155 NDUFS2 ZNF587B ODF2 SMARCAL1 COASY CDNF HELB SETDB1 KLHDC4 MRPL27 PHKG2 KIF11 MCM3 AP1M2 POLR3C CCDC148 RAD51AP1 SPATA17 FDXR ARL16 HSPBP1 TFCP2 DDX56 INCENP ZCRB1 RASSF6 TERC CDKN2C KIAA0556 ANAPC5 ING4 RNPC3 CDK12 WDR5B SSBP1 CCDC61 RFWD3 AP3D1 PICK1 KIAA0753 ZSCAN25 AAGAB TYW1 POC5 AP5Z1 RNF181 NUP205 TTI1 TTC16 WDR24 ZKSCAN5 UNC45A CHCHD2 PARS2 TELO2 C19orf44 SEC16B SPG7 PSMA5 MAN1B1 LONP1 CENPQ MLEC CSNK1G1 OS9 FZR1 PKP4 ACAD10 CLTA LIN37 TMEM186 GFM2 C15orf41 IQCH SND1 SIL1 C12orf73 ZBTB45 ELAC2 ATP13A1 CNDP2 ARHGAP12 BAZ2A SH2B1 TMEM234 ACBD5 GTF3C1 PPHLN1 VPS25 RPRD1B WDR34 RIN1 FAF1 MRPS23 UBXN6 PPP6R1 GMPPA NOL6 MCM6 STAMBP WDR83 RPL7L1 CD2BP2 MALSU1 EIF3D SLC35A3 SCYL3 LRCH4 AATF PRSS16 KATNB1 MRPL51 SMARCC2 STK35 GOSR2 U2AF2 CEP152 ZSCAN16 DUS2 GTPBP10 ZNF580 ZNF837 ZNF622 B9D1 RBM42 ZNF169 GTF3C2 RNF121 WDR4 CEP164 CAPN10 ZNF384 TRIP4 PFKM COPA ZNF217 UBAP2L TMEM260 XPC POLR1A DNAJC14 ZMAT2 TRUB1 HGS FIS1 TMEM9B-AS1 SIGMAR1 SF3B2 ENO1 TMEM38A TPRN COX17 ALPK1 MZF1 FTSJ3 TRAPPC6A ANKRD11 SLC33A1 COPE INO80B SLC38A10 MBTD1 DGUOK SPHK2 CXorf40A SH3RF2 UTP18 GSK3A EIF2B1 CDK11B CRB3 PNPO DEPDC5 LCMT1 ZNF688 TNPO3 GGA1 OPA1 AP2B1 NSL1 TOMM40 ZNF774 TIMM10	up	*
AATGTGA_MIR23A_MIR23B	0.0028174	0.0277229	0.4317077	-0.2278672	-1.309729	353	CPEB2 GREM2 TTC7B QKI ZCCHC2 ELF2 INPP5A TGFBR3 VAPA LAMP1 ZBTB2 TGFBR2 TRIB1 SEMA6D KCNK3 PICALM GLS CAMTA1 DACH1 SIRPA CRK SPRY2 PPP1R13B ZEB1 HNRNPU UBE2D3 ATP6V1B2 TBC1D9 RUNX1T1 ZNF423 GRK5 SCAF4 NPR3 CADM1 EPS15 AFF1 NCOA1 C2orf69 GPBP1 TMOD1 RYBP CDC40 PKNOX1 SGK1 PHACTR2 SEC14L1 CPEB4 MAP4K4 WTAP PTGER4 DHX15 FBXO11 CXCL5 SNX22 EGLN2 NDST1 CELF2 MSMO1 FOSB TSHZ3 PKIA NAP1L5 BTBD7 ING3 AZIN1 TGIF1 DUSP5 CBFA2T3 C16orf72 ATXN1 PHF19 MEIS1 WBP2 STX12 MICU3 CSNK2A2 PDE4B DBNDD2 CCNH ELF5 PITPNA BNIP3L UBE2D1 IPO5 MEX3C BRWD1 G3BP2 SSH2 KPNA4 STK4 CUL3 MTUS1 FAM13B NAA15 TLK1 SPOPL ZBTB44 PPP1CB IRF2 GREM1 ATP11B UBA6 LHFPL2 HAS2 CSNK1G3 CCNT2 PRTG OTUB2 HMGN2 MTSS1 AKAP12 ANKHD1 PAXBP1 IRF1 STARD5 SETD2 ROBO2 RAB11FIP2 PLCB4 FNIP1	down	*
MIR372_3P	0.0038881	0.0355170	0.4317077	-0.2373477	-1.309128	288	RAB11FIP1 TMEM100 EDNRB FGD5 TMEM170B GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TXNIP ASAP1 LATS2 MTF1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PTPN21 REST PDE8A NPAS3 ST7L CYP20A1 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PPP6C C2CD2 ARHGEF10 RABGAP1 ZNRF3 RASSF2 SNRK CELF2 PKD2 TSHZ3 SPOP ZRANB1 SKIDA1 ZBTB11 MAP3K2 RELL1 TAGAP KAT2B PRDM8 INO80D ITPRIPL2 RTN1 TIAM1 MFAP5 PAK2 MTUS1 LYST RORA ANO6 MIER3 TRIM36 IRF2 ZFYVE26 PLAG1 ARHGEF17 CFL2	down	*
MIR6809_3P	0.0010498	0.0131988	0.4550599	-0.2224148	-1.308860	436	FFAR4 TRIM71 EPAS1 USP12 GREB1 GREM2 MBOAT2 PTPRB BMP2 ARRDC4 TMEM170B SLC10A1 AATK STXBP6 LDB2 DDX6 RASAL2 NEDD4L SLC39A8 INPP5A MEF2A USP47 ZBTB2 RHOA ERG SEMA6D ZNF385D SLC36A4 SLC25A17 TACC1 CHMP1B ANPEP PEX5L PPP2R2A SLAIN2 PLXNA4 HNRNPU PDE4D HPSE2 MYCT1 PRDM16 C14orf132 MEFV PPP6R3 BST1 PIP5K1B SETD9 THBS1 MYRIP DPH3 RIT1 RBMS1 ATF3 ELAC1 ADIPOR2 NCKAP5 CMTM6 CNOT6L CDKN2AIP FOXN3 ZNF426 SERTAD2 SYNPO2 DNAJC27 UTRN TMTC1 CPEB4 PDE5A CCDC50 FOXN2 PTGER4 BAG5 FBXO11 TTC14 SP3 PI4K2B KLHL18 ENTPD4 SNX1 NIPSNAP3B GAS2L3 BLOC1S6 GPRIN3 GPR3 SLC25A24 YPEL2 HIVEP2 ZNF175 STXBP3 DCAF5 ZBTB1 YTHDF2 ZNF844 ZNF136 SLC8A3 WBP2 ADAM10 INO80D AMD1 PDLIM5 SETDB2 SIK3 TOB2 ALDH2 RBMS3 TBCEL CUL3 DOCK10 SCAI PAK2 TMEM87A THRAP3 CREG1 SHISA6 EHD4 PURB HPCAL4 SPATA13 PAPSS2 MS4A2 ZNF326 REEP1 KALRN ACVR1C CDON CHML	down	*
ZFHX3_TARGET_GENES	0.0001743	0.0030572	0.5188481	0.2542567	1.308300	1385	ATP10B RPL13P12 RIBC2 HP HELLS C1GALT1 HOXB-AS3 CEP89 CDC45 TICRR PMFBP1 LYSMD1 NUP107 CCNB1 POLQ UBE2T PBK GCNT3 PIF1 RGMB-AS1 BRCA1 CDCA7 MRPL46 METTL1 GINS1 CDCA2 HILPDA DBF4B NOL12 STK31 STIL NDUFS6 TTC26 CEP70 NUF2 YEATS4 EFNA4 IFT27 CENPA ACAD9 ALDH18A1 ACOT8 CCNB2 MCM4 LSR RAD54B XPNPEP1 FBXL19-AS1 CKLF-CMTM1 ORC1 EIF3B PLS1 TDRKH GON4L LIPE-AS1 CAND1 FSTL4 NCAPD2 AVL9 CDK5RAP3 KRT15 CCT2 PCDHGA8 SPDL1 TNC LDHB SIPA1L3 GOLPH3L TJP3 C5orf34 POLR3A PLEKHG1 BZW2 HMMR C19orf48 SMARCC1 ZNF391 RPL4P4 EMC9 AP4M1 TPBG CCDC77 TOP2A EXOC4 RPL32P3 CCT5 RFXANK AURKA C20orf96 GTPBP3 MT-TY KIF2C MCM7 MAD1L1 E2F2 CENPW POC1A HYDIN CDCA5 PRKDC RNF43 SETDB1 AMACR ERAL1 SLC4A11 KIF11 MCM3 CDC25C ZNF785 TARS2 ANG RNFT2 SMYD5 LRRC66 SIDT1 HPR ZNHIT1 ZNF786 PEX26 ORC6 ACTL6A MAD2L1 NFYA KIF3C THAP10 DNAAF3 MRPS11 LRRC61 FBXL19 GRHL2 MRPS30 PHB FBXO16 CNOT3 ALDOA C4orf47 MGAT4B SPRY1 TRIT1 DYRK2 PSRC1 DDX56 CKLF CKS1B MRPL36 EFCAB11 NUSAP1 TMEM106C HARS2 MRPL37 KIAA0556 ANAPC5 KRT18P31 WDR5B SSBP1 ZNF440 RFWD3 PICK1 CCT3 NUDT2 KIAA0753 PHF12 ANKRD54 POC5 DGAT2 WDR31 AP5Z1 PMEL BPGM ACTR3C DHX33 TRIM41 KSR2 NUP205 PSMG3 POC1B TAF6 METTL3 RNF207 OARD1 SLC44A3 MTBP NOP2 TMEM231 CENPP C9orf43 IFT52 UNC45A ZNF692 RANGAP1 CHCHD2 MYO19 DNMT1 ZNF687 ACBD6 MOV10 UBFD1 ILF2 CDC23 SATB2 NADK2 SNORA70 NDUFA11 VPS41 DNAJA3 ADAT1 MNS1 FHIT AARSD1 DHODH PTGES2 GPRC5C MRPL11 IQCG TIGD6 COX7C TK1 C1orf131 NFATC4 ZNF239 ARHGAP5-AS1 CENPQ RHBDD3 MLEC SOX2-OT MTND5P11 VIL1 ITFG2 MAPK10 ZSWIM3 ZSWIM1 KRBA2 GFM2 SYNGAP1 SLC9C2 C12orf73 FXYD3 NUP85 PRRG2 MT-TH CCDC159 ENC1 ELAC2 SLX4IP NR6A1 CENPK CLDN12 EFCAB7 LSG1 GTF3C1 LINC00910 PWWP2A PSMB3 MT-TR TMEM106B ORMDL2 RPRD1B CENPM RIN1 LINC00467 CA11 SIRT4 MAN2A1 EFHC1 ASCC1 BCL2L1 HMGB3P22 SRRT FANCM MRPL24 PLEK2 BLCAP MRPS33 ANKIB1 DYNC1LI2 TBCA WDR83 RPL7L1 UBL7-AS1 MED24 PRMT1 NOSIP USP21 KPTN ZNF783 ANKRA2 TDP1 ZRANB3 SNRPD1 UIMC1 PARP14 EIF3D HAX1 RAB3D LRCH4 KATNB1 EXOSC5 MRPL51 RGMB RCC1 CCNG1 ATAD2 TCERG1 GNAL KLHL7 NUP62 MICAL3 GLO1 MSH2 MAP3K14 RBM42 HDLBP TMEM117 CISD3 BBX ECH1 SCNM1 RNF121 TXNL4B DOHH NAV1 CCDC9 ATOX1 N6AMT1 TRIP4 NBR1 MTIF3 ZWILCH TOMM40L FBXW11 ARHGAP5 GTF3C5 SAMD4B NDUFA8 NME7 FAM118B SNX8 AGBL5 ATG2A ZNF131 CIAPIN1 SMC2 GNA12 BCAS3 TARBP2 BCL6 TMEM260 CENPE POLR1A ANKMY2 PRPF3 FIS1 BPNT1 MRPS27 PPIA UBE2C CYSTM1 PNN GPN1 DCAF11 MRPL48 CCDC91 LXN TK2 CLASP1 TRUB2 FAM222B PTPN13 SART3 ZNF33A C12orf10 MSANTD4 ACSL5 IFI16 ANKRD11 TMCO6 CYB5B CLNS1A SLC33A1 CSTF1 COPE KIAA0586 TOMM7 DNAL4 RTN4IP1 CNPY4 INO80B RPL23A PLAC8 VPS18 MORN4 PDXP SETD1A MRTO4 MED16 WDR55 MBTD1 PPP1R13L PDK2 TFG UTP18 PTPRK CRAT AKAP9 TMEM259 CNKSR1 ZC3HC1 PNPO HINT1 ABHD2 TNPO3 NFE2L1 GGA1 OPA1 DLGAP1-AS2 MEGF11 TOMM40 SLC2A8 ZNF774 MCEE SLC4A1AP GLRX5 ZNF77 NPM1 IMP4 MTMR4 BTN3A1 MTR RPLP0 RUFY1 SLC27A5 CACTIN IMP3 USP49 DMTF1 AP2A1 NDUFB2 WDR89 CCDC86 NAE1 SMAD3 HNRNPAB PLOD3 MTF2 TXN2 LRPPRC AFMID TIMM9 PSMD3 PPP2R1A STRIP1 INTS9 DHX38 CALM3 BNIP1 ORC5 PAN2 COX6A1 EVI5L DDX49 PLEKHH3 SLC12A9 KIF3A PAWR FIBP CCDC124 RAB4B ZNF691 COQ4 GLCE ZNF839 STMN1 ZCCHC7 OIP5 TMEM14A SLCO4C1 SNHG10 MSL1 IK HNRNPA1 MPLKIP ABCB8 ACOX2 SUCO ZNF460 DAD1 NDUFA9 WBP1 KLHL20 HMBS CLTC KHSRP BUB3	up	**
BPTF_TARGET_GENES	0.0022417	0.0233494	0.4317077	0.2569979	1.307289	881	CCNO CPHL1P PRR15 KIF12 PRLR KCNMB2 ABCA13 MEX3A EYA1 RUVBL1 BDH1 TFAP2A NUP107 ANKFN1 IGF2BP3 UBE2T C17orf75 MUC4 DDIT4 PHF14 RGMB-AS1 STAB2 ECE2 METTL1 LCN2 XKR4 FABP6 ANLN COL28A1 ASPM EIF2B5 CEP70 NUF2 YEATS4 ALDH18A1 ECT2 CUEDC1 TFDP2 TRIB3 STC2 C4orf19 CYP46A1 GALNT10 PLS1 CLCN2 KIAA0895 CAND1 DZANK1 MRPS35 KCNG3 LDHB GOLPH3L CEP250 CLDN1 CASP2 TMEM41A BZW2 DLG1 KIF23 SYTL2 BICD1 FOXJ1 IGF2BP2 FRS2 KCNMB3 ZNF766 MAD1L1 CPD ABCC5 SMYD2 RNF43 WNT1 ERAL1 MRPL3 TRPT1 SNHG11 LINC00511 XXYLT1 SOX4 SARS2 SPINT1 DNAJC9 PA2G4P4 SCAMP5 EHHADH ABCB9 MDM2 TMEM63A BACE2 MGA ETFA INPP4B LRRIQ1 LRRC45 NOL3 RGS4 TRPV4 NRG4 ALG3 C7orf26 R3HDM2 RECQL5 DDX56 TNIK GPX8 RNF216 MSTO2P SIDT1-AS1 ACVR2B-AS1 TMEM106C LRRC6 CTDSP2 EXOSC2 EEPD1 PLCH1 TNK2 GMNN SRCIN1 NPM3 PGBD2 TRIM2 ZNF815P PMEL TRIM41 PSAT1 DPH7 ANAPC7 POC1B CCDC57 FOCAD RAPGEF5 SRD5A1 DNAJC7 KPNB1 EFTUD2 POLR2H POFUT1 THNSL1 VWA5B2 SNX27 VPS41 GALK2 ZNF133 MBD4 SLC37A4 TIGD6 ENAH ESCO2 SOX2-OT SLC22A5 SRGAP1 DUSP8P5 HECTD1 MTND5P11 ANP32E ACAD10 MAP6D1 SPA17 TMEM186 RPS7P11 KRT19 CDK13 PSMD2 MT-TH JTB POLB ZNF140 TCEA2 DNASE1 NR6A1 PROX1 LSG1 PWWP2A PSMB3 KCNB1 AGBL2 PLD1 TCTN1 FAHD1 HMGB3P22 RPA1 CLINT1 ASRGL1 FCHSD1 CAPRIN2 HEATR1 SPINK5 RABEPK PARP14 TBC1D16 PIP5K1A SKAP1 MYEF2 PIGX RGMB SUOX SLC1A5 RAP2B ANK3 C1orf122 DDX55 COPZ1 STRBP INTS8 PYCR1 SUV39H2 FCF1P8 RPS26 ULK4 SNORA60 DDX54 HEATR5A RPL9P29 RN7SKP296 RFC5 RNF157 PDAP1 STAT6 CDK5RAP1 TMEM44 ARRDC1 RAD51 TNKS1BP1 TRAPPC9 RPL6P7 GRAMD1B MROH1 ENKUR ZNF621 GRM6 WDR49 TCF25 TMEM101 NUBPL RNF7 TNS3 UQCRQ ZNF131 GNA12 TARBP2 EIF4G1 SRCAP FZD3 CLNK MTHFD1 SRPRB TRUB1 MCF2L2 KDM5B TIMM44 RFNG RNLS RN7SL381P NAT10 NLGN1 SH3GL1 CLASP1 DDX41 MTG2 KLHL2 SETD5 RAD51-AS1 FBXL18 LYPLA1 GRIP2 SLC33A1 CYHR1 NDUFAF6 LASP1 VPS26B RPS20P15 DNAAF1 PSTPIP1 MIOS ST8SIA1 SPIDR	up	*
MIR4753_3P	0.0008784	0.0115068	0.4772708	-0.2215853	-1.306356	443	TRIM71 CXCL3 LPIN2 EDNRB GREB1 SOWAHC CPEB2 GREM2 PTPRB KL ARRDC4 ZBTB34 CGNL1 DDX6 NEDD4L CRY2 FLVCR2 SLC39A8 INPP5A CTDSP1 PRPF38A STX11 MEF2A KCNN3 TET2 ACER3 HEG1 RHOA ZEB2 SEMA6D DNAJC3 ZNF385D PPP1R15B PLXNA2 PAG1 DES SLAIN2 PLXNA4 SPTBN1 ZFYVE16 EPM2AIP1 ITSN2 PDE4D MYCT1 PDGFA PRDM16 KIAA0513 PIP5K1B REST PLEKHM3 DPH3 TBX5 RBM44 PDE1C BACE1 NCKAP5 IKZF5 CREM PHACTR2 PDCD6IP UTRN NDNF TMTC1 HRH1 APBB2 FBXO11 GLIPR1 TTC14 SP3 PIK3R1 SDHD KLHL18 SNX1 TMEM167B PRKACA PDZD2 CXCL5 RALB CELF2 GAS2L3 BLOC1S6 RNASEK YPEL2 HIVEP2 MARC2 PPP2CB GOLGA8R STXBP3 YTHDF2 CD86 PCDH17 SLC8A3 UTP3 WBP2 PLAA ADAM10 ABI3BP AMD1 RNF138 PDLIM5 RPP30 EPB41L5 SIK3 TOB2 RBM18 ALDH2 ALDH6A1 MEX3C OSER1 SCAI PAK2 TMEM87A LYST RORA CREG1 EHD4 PAPSS2 MS4A2 ZNF326 PSIP1 ACVR1C GREM1 SERPINE1 TNFSF8	down	*
NUYTTEN_EZH2_TARGETS_UP	0.0000759	0.0015310	0.5384341	-0.2074948	-1.306336	911	SLC31A2 KMO HMOX1 DENND5A ROBO4 GLIPR2 ZC3H12C CPEB2 IL1B THSD1 WNT4 LPXN PTP4A2 MIR22HG LIPA TTC7B ARRDC4 ZBTB34 BDNF EGR2 CD44 LMO2 CCDC88A SAMHD1 BACH1 ST3GAL6 BAG4 CORO1C MYADM BAIAP2 THAP2 QKI FLVCR2 MYD88 TBC1D7 BMPR2 ZCCHC2 S1PR1 MSRA SLC15A3 MAL CDC42 NCF2 GAS6 TGFBR2 RFTN1 SYNC TXNIP ANXA1 WWC2 STARD4 SLC44A2 LACTB UBL3 TM2D3 ADAM17 CLEC7A CYB5A EIF5 AHRR PBX3 ACOT2 ANXA5 REV3L ANPEP PAQR3 KLF6 MALL PTX3 CLN5 STOM MOB3C ADRB2 TMEM41B MCL1 TMEM38B CD58 PPP3CC KPNA5 CPED1 DUSP3 TLE4 FOXO1 SCP2 BIRC2 KIAA0513 PPM1K CASP1 KLF4 PAQR5 ANKRD10 DRAM1 THBS1 TMED5 STX3 DENND3 GRK5 SOCS5 CLIC4 SPAG9 ITIH5 GMPR CDKN1A UBE2E2 EPGN CXCL2 ATF3 ID2 PNRC1 ACTR3 INHBA ADIPOR2 DSE MATN2 GNAQ OXSR1 PAFAH1B1 TP53BP2 IL24 BACE1 EFR3A CNRIP1 GLB1 TDRD7 NINJ1 ARHGAP17 TMEM9B RBPJ PPP2CA DDX60L RNF149 IL6 SAR1A SGK1 PNO1 PLEKHA3 RAB8B HCFC2 OASL AQP3 CYB5R1 JUN ARL5B JUNB OSTM1 DNAJA1 NXPE3 APBB2 RCAN1 FERMT2 FYTTD1 PODXL CD83 PRKCE IDS KBTBD8 COBLL1 MORC3 OGFRL1 YWHAZ GFPT2 PXK SNX9 RHOQ AZI2 NECAB1 PKIA DAGLA UBXN2A AKIRIN2 EHD1 TCF4 PEA15 DCAF5 ZBTB1 MILR1 KCTD10 ABHD13 VAMP4 C1orf116 ATP6V1A MIA3 APLP2 SOD2 LGALS3 BRI3 CCR1 PHF11 STK40 GATA6 GNA13 ACYP2 MFSD12 CLCN6 CLEC2B POLK ETS2 GTF2B CCL20 RNF2 GEM ICAM1 ABL2 CPQ TNFAIP8 RLF FKBP1A WDR1 SERTAD1 TXNDC15 NBN XKR8 MGAT2 NT5C2 CDC42EP3 PIP4K2A TAB2 RIPK2 NLRP3 SP100 MT1M NUP98 ZDHHC21 TRAF1 SOAT1 RBMS3 S100A4 TMEM109 FDX1 FNBP4 NHLRC3 NFKBIA GLRX2 CEPT1 CTSC EDN1 TMEM87A TTC19 LYST DNAJB9 CYTH1 AIM2 KIF1B THEMIS2 NR3C2 GRB10 MT2A ZFAND2A BANK1 PMAIP1 NIPSNAP3A SPHK1 PPP1CB IRF2 CSF2 KLC1 ZFYVE26 GUSBP4 HERPUD1 SPSB1 EGR1 SERPINE1 GHR SAP18	down	**
GO_ENDOSOME_MEMBRANE	0.0020647	0.0219787	0.4317077	-0.2246115	-1.305334	400	SLC6A4 MCOLN1 OSBPL11 TMEM150B SNX10 DCSTAMP HSD17B6 PCSK9 FIG4 PLEKHF2 CAV1 CORO1C MYD88 ARL8B CD1C LAMP1 SLC11A1 GGA2 ANXA1 SPG21 RILP CHMP1B ZDHHC2 LITAF CYB561A3 ABHD6 ADRB2 TRAF6 LAMTOR3 WNT3A ZFYVE16 UBE2D3 TFRC RAB14 RHOB RAB12 ITM2B CDIP1 MVB12B MYO1B LY96 CTSD TMBIM1 IRAK2 AQP4 ATP6V0D2 TLR4 ARC PLEKHB2 EPS15 TM9SF2 HLA-DQA1 BACE1 CMTM6 TBC1D5 SNX3 TMEM9B CD8B VAMP3 VPS37A GPR61 KIF13A PSEN1 INPP5B APPL1 RAB8B PIKFYVE RAB31 OSBPL9 ATP6V0B VPS26A SNX2 STX7 EEA1 RAB8A SNX1 GRIA1 APH1B ATP6V0D1 UBB CD164 EHD2 SORT1 EHD1 CD1D ZFYVE9 SBF2 MTMR2 ATP6V0C FCGRT STX12 VPS39 CLCN6 LDLRAD4 CHMP3 PARM1 RAB5A ACAP2 VPS4B EPHA4 TAB2 GIMAP5 BOK STAM2 RET MCOLN2 MMD ITCH LDLR EHD4 RNF13 EHD3 SPHK1 RABGEF1 ATP6V0A1 UBAP1	down	*
MIR3658	0.0004285	0.0064921	0.4984931	-0.2116172	-1.305306	666	RTKN2 TMEM100 SC5D COL25A1 SASH1 ABHD5 SLC12A6 GPR15 CD55 ATXN3 SNX10 NUP54 GPR65 MBOAT2 RAB3C INSIG1 GPC5 TMEM170B KLHL8 RASAL2 LONRF1 QKI BMPR2 IDI1 PRKAR1A TET2 CBL SLC11A1 ZBTB2 MOB1B TEX2 HEG1 ZEB2 ZBTB4 KIAA0355 WWC2 ATP2B1 DNAJC3 SLC36A4 SLC25A17 SBDS PCYOX1 PPP1R15B CHMP1B SDE2 C1orf21 ABCG2 MASP1 RNF144B LITAF ZBTB21 HIPK3 DACH1 SLAIN2 PPP3CA RB1 SLC25A37 TFEC EPM2AIP1 BTG3 AMOTL1 FOXO1 SCP2 LIN7C PEG3 RUNX1T1 PRKD3 UHRF1BP1L ZADH2 TMED5 FBXL3 SPAG9 MGAT4A CADM1 GPR85 CYP20A1 USP44 PTGER3 ZMPSTE24 GCA CLIP4 SPRYD7 PDE1C CNOT6L CDKN2AIP CNRIP1 FOXN3 RAB6A SERTAD2 MYLIP PDIK1L LRRTM2 PHACTR2 PLEKHA3 HCFC2 ARL5B GABPA ZFP91 ETS1 ADRA1A BMP3 FOXN2 IPO7 EEA1 PNPLA8 LYRM1 GPR183 MAPK4 ZNF555 GRIA1 NAA30 ZNF407 WDR7 CELF2 CDK14 PLCG2 AGFG1 SNX9 SLC25A24 RHOQ AGPS NECAB1 HIVEP2 KLRC2 NAP1L5 BTBD7 HNRNPD NUP153 ZBTB1 DCK ZCCHC10 KHDRBS1 MCUR1 MAP3K2 CSDE1 GNB4 PPIG CRY1 MICU3 PGGT1B ABI3BP GEM BNIP3L INTS6 INO80 EPB41L5 ZNF438 PUS10 SEC63 BLOC1S2 B3GALNT1 CYB5R4 FBXO30 TOB2 RBM18 UBE2D1 NUP98 SOAT1 LYSMD3 FDX1 TTC28 RAB2B GTF2F2 RNF38 SCAI PTEN B3GNT2 KIF1B TMCC3 FAM13C LDLR NABP1 MAPKAP1 DUT PURB ARFGAP3 ZBTB44 PAPSS2 PPP1CB RABGEF1 HAT1 YTHDC1 MB21D2 GHR CLOCK MZT1 SH3GLB1 FAM8A1 TBC1D23 PLXDC2 CCNT2 ADAMTSL3 PIK3CG COX20 DNAJB4 PRTG CEP44 LMO7 WDR41 CCDC93 PAX5 WDR47 HMGB1 MAN1A1 IL5 PAXBP1 CUL2 PYROXD1 DR1	down	**
RAO_BOUND_BY_SALL4_ISOFORM_B	0.0018700	0.0203114	0.4550599	-0.2244831	-1.304309	399	MGAT3 CD55 CPEB2 TMOD3 CCDC88A RTN3 CITED2 FOSL1 BMPR2 GTF2I ELMO1 ZBTB2 RCHY1 IER2 EDEM1 SLC19A3 PLA2G7 B3GNT5 ENTPD1 PPP1R15B ABCG2 EMILIN2 LUZP1 RNF125 M1AP GPBP1L1 IFNK NFE2L2 SFRP1 SPTBN1 NODAL PPP3CC PTPN12 TBC1D9 MOAP1 SRSF5 BIRC2 DENND6A NOSTRIN KLF9 ANKRD10 OSTF1 SOCS5 ITPK1 GSDMA ID2 UBE2B SMAD7 ZNF706 PEF1 HES1 VCPKMT GNRH1 UFM1 SPIN1 RBPJ ARL6IP5 ETF1 SLC25A3 PPP2CA PHTF2 NSMAF LRRTM2 KIF13A DCTN6 OSBPL9 DDX17 SHOC2 RCAN1 IPO7 PNPLA8 SP3 SERPINB6 REL ZNRF3 NAA30 CGGBP1 DEDD RNF146 SLC3A2 SPRY4 MYL12A SYPL2 FAM204A ZFAND6 CHIA VAV3 ITGA9 NDUFA5 ZRANB1 TGIF1 CCP110 FEM1B TMEM230 PDLIM1 CCDC68 MEIS1 NQO2 NPTN TCF7L1 IST1 INO80 SPARCL1 TFPI RTN1 EPN2 RTN4 CXCR4 EPHA4 IPO5 PSME4 KIT B3GNT2 MTUS1 ANXA11 SFPQ CNOT8	down	*
MIR548AJ_3P_MIR548X_3P	0.0002532	0.0042074	0.4984931	-0.2060774	-1.303787	789	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C MBOAT2 RAB3C FYN CCL3L1 CALCRL QKI GTF2I SLC25A30 DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ACER3 ZEB2 ARHGAP29 SEMA6D CNST STARD4 MCTP1 HBEGF SGMS2 TM2D3 ADAM17 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L FOXJ3 PPP3CA RB1 TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FBXO8 FLI1 SLC7A2 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 PDE1C AFF1 BACE1 TLL1 CNOT6L LIN7A AFF3 STK24 USP25 SERTAD2 UFM1 MOB4 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM ASNSD1 YBX1 COPS2 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 NOTCH1 CPEB4 KCTD12 ETS1 MED30 BMP3 TMPRSS11D OSTM1 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 ZBTB24 MORC3 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS RHOQ PELI1 AGPS CDK17 KLB YTHDF3 PKD2 NAPG MAPK8 XYLT1 BTBD7 ING3 MME AZIN1 KIAA0232 DCK SERPINB1 PDS5B ABHD13 GNAI1 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 CDKN1C VPS4B CYP2U1 ITGAE ARL14EP UBE2D1 ZDHHC21 CREBBP SSH2 SOAT1 KPNA4 RBMS3 STAM2 BCAT1 SCAI PAK2 SKI NFU1 CECR2 FAM126B MMD CAMSAP2 C21orf91 TMCC3 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	**
ZNF134_TARGET_GENES	0.0020889	0.0221906	0.4317077	0.2561503	1.301371	823	CEACAM1 PTGES MEGF10 HOXB-AS3 CEP89 DNAH2 MCM10 EPN3 CHEK2 C1RL-AS1 B4GALNT4 NEK2 DROSHA FBXO27 WFDC2 PDCD2L CYP2J2 TTF2 SLC25A21 ZNF138 METTL1 ZFHX2 CDK4 C4orf50 ZNF285 FLAD1 SEC14L5 ACAD9 ZNF714 STC2 GOLGB1 KCNT1 SMPDL3A SPINT2 ARHGAP33 GRHL3 FBXL19-AS1 PDE9A ZFP64 MYL6B NUB1 KAZALD1 WDR62 C5orf34 STRA6 DYRK1B ZNF391 BBS1 STAP2 TP53BP1 CCDC77 LGMN EXOC4 TMEM184A HOMER3 EME1 SPTB HHAT POLA2 GTPBP3 IRF3 MCM7 C1RL RGL1 ADAMTS13 CCDC114 ZNF146 DCDC2 MRPL27 BLOC1S1 SEC61A1 SARS2 POLR3C SCAMP5 NFYA KIF3C THAP10 IPO9 FBXL19 BLM PHB C2CD3 ALDOA NRG4 SPRY1 R3HDM2 OSBPL7 PARP1 ZNF229 FGGY APLP1 ANAPC5 SSBP1 PACS1 PHF12 GOT2 ACP6 ZNF541 SLC16A13 TRIM2 PSMB5 STAT2 DNA2 SEC61G PMEL ZNF584 FAM186A CCDC88C LINC00649 OARD1 NAPEPLD CCDC57 CBFA2T2 C9orf43 STK11 ANXA2R ZNF500 GAL3ST4 CATSPERG ILF2 TAPBP DLGAP5 PDCD11 NDUFA11 ZNF233 CNOT2 PSMA5 ALDH7A1 ZNF133 SNRPA DHRS4-AS1 MC1R OSBPL3 KIF22 ROGDI ARHGAP5-AS1 ZNF761 ATG9B GINS2 HIP1R MTND5P11 TJAP1 AGPAT5 SPAG1 KIF20B LIN37 SRD5A3 OTX1 ENOSF1 TMEM186 TM9SF4 NTN3 BCL2L12 S100A13 FAM200A PRRG2 PPME1 NT5M DNASE1 PPIEL MDGA1 LIMA1 LINC00910 UBE2O PPHLN1 TUBG2 FTCD ASB6 ZNF428 ZNF616 TCTN1 UBXN6 CDR2 KRT8 KDM4B ZNF160 PPCDC RAI14 NSUN6 NOSIP HHLA3 ANKS3 HEATR1 C5orf22 NFE2 PRSS16 CREB3L2 TTLL6 CCNG1 PHC2 SMARCC2 TCHP U2AF2 TPM3P9 PRPF18 DZIP3 RTEL1 ANAPC2 DOHH CCDC167 PAK4 STAT6 ZNF436 VPS33B PRSS22 ARRDC1 BMP8B ZNF292 ARHGAP5 COPA TEPP SRP9 MRPL21 KIAA0825 LINC00240 AGBL5 HOXB2 TMEM101 PTPRF SNORA14B NUBPL TBCB MXD3 SNUPN ALKBH6 ZNF131 OSGEP POLR1B TARBP2 SYNRG MAPK8IP3 SRCAP E4F1 MPG FZD3 POP4 NPTX1	up	*
GO_SUPRAMOLECULAR_COMPLEX	0.0022259	0.0232504	0.4317077	0.2553002	1.301361	943	KIF1A SAA1 KIF12 KLC3 MEX3A KIF20A MYBPH MDM1 HJURP KRT5 PKP2 DNAH2 RPGRIP1L BUB1B NUP107 NEK2 CCNB1 CENPF TNNI1 KIF18B PKP1 COL27A1 SLC2A1 NDC80 TUBB2B TTK RACGAP1 GTSE1 KIF14 SPAG17 ASPM COL7A1 PLK1 NUF2 KRT16 AURKB CENPA TPX2 CMYA5 DNAH3 PMS2 PRC1 GRB7 PLS1 DYNC1I1 TDRKH CCT6A KIF27 ZWINT MYL6B CDT1 CDK5RAP3 KRT15 DNAH14 CCT2 DCTN2 SPDL1 NME1 MICALL2 DNAI1 HAUS5 RSPH1 TTLL4 TNNT2 NOS1AP DLG1 MAP7 KIF23 BOD1 BICD1 KIF15 TP53BP1 KNTC1 KIF3B BUB1 FBF1 IDO1 MAP10 MYBPC2 CCT5 GPER1 AURKA REC8 ODF2 TPR FLG KIF2C MAD1L1 CD2AP CENPW MAP1LC3C TEKT2 FSD1 NSUN2 HOOK1 DCDC2 FHOD3 KIF11 LMNB1 DNAH8 MAD2L1 NEB CENPO GAS8 KIF3C SPC24 DNAH11 SYMPK FLNB CNOT3 ALDOA TRPV4 PARD3 MYO1A BTBD2 PSRC1 INCENP KNSTRN MYOT NUSAP1 CBX5 PAK1 KRT18 CDK1 DNAH6 KIF5A CENPJ CENPH BIRC5 CCT3 TTLL9 JAKMIP1 DIS3L2 SCTR TNNI2 KIF19 SPAG6 KIF2A NARF KIF7 LARP1 COL3A1 DYNLL2 SPAG5 TRAPPC12 MTBP DNAH5 PRKAA2 KLHL22 SNCAIP KPNB1 EIF6 RANGAP1 UPP2 MOV10 PABPC1L COL1A1 TUBG1 COL1A2 DNAH7 CNOT2 DNAJA3 NINL LMNB2 MNS1 TUBB2A TUBA3D KIF22 KY COL5A2 DNM1 DBN1 TUBA8 CENPQ SCN8A KIF21A GAS2 HID1 MAP6D1 KIF20B LRWD1 TRIM32 SMTNL1 KRT19 FHL2 AHNAK2 TWF1 NUP85 POLB CCT7 CENPK COL11A1 KLC2 KLC4 CENPV CKAP5 ABCC9 CENPM TUBG2 TTLL3 FBXO22 CDK5RAP2 KRT8 DYNC1LI2 KIF21B EML6 TBCA CENPT CKAP2 COL5A3 DNAI2 KPTN ANKRD1 HAUS6 DYNC2H1 FAM161A HAX1 RAB3D KATNB1 SKAP1 MYH7B TTLL6 HAUS4 LSM4 MYH3 ANK3 NEFH TCHP KRTAP5-9 CKAP4 MYH13 MICAL3 APC2 SCO2 DCPS DBNL NAV1 TUBGCP4 SYBU ACKR2 CCDC181 DNAH1 HOOK2 TUBA4B ANK2 CARHSP1 TPGS2 NBR1 ZWILCH SEC13 NOS1 FBN2	up	*
MIR519D_3P	0.0015256	0.0174669	0.4550599	-0.2157764	-1.300843	528	RAB11FIP1 EREG TMEM100 ABHD5 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	*
YAGI_AML_WITH_11Q23_REARRANGED	0.0046652	0.0405343	0.4070179	-0.2333260	-1.300025	284	SASH1 TSPAN4 TAL1 ADCY9 EMP2 CLDND1 COQ2 FOLR1 ST3GAL6 GTF2E2 QKI TBXA2R NR3C1 CYP4A11 NFATC3 HPS5 HSPG2 ERG NFIX ADA TACC1 ENTPD1 PBX3 ANXA5 ANPEP LCP1 CLN5 DACH1 RB1 GPM6A PLAUR OSTF1 SOCS2 CDK9 MPL NPR3 GMPR LAPTM5 CADM1 CCND2 ALOX5AP ELK3 N4BP2L1 PPP2R5C WFS1 LIN7A CSTA TMEM251 ENPP4 GYPC IDS PLCG2 SMPDL3B WHAMMP3 NR2C1 TEX30 GNAI1 PIM1 ATXN1 CD81 CTIF MEIS1 PHF2 ADAM10 PPID MBNL1 SF1 CALCOCO2 ITGAE GLUL RET JMJD1C TIMP3 CCND3 FEZ1 BMI1 EVI5 DMXL2 ELP4 ARHGEF18 VPS13D EXOG	down	*
TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497	0.0012115	0.0147544	0.4550599	-0.2194414	-1.299684	505	SLC6A4 WEE1 PNPLA6 SOWAHC CPEB2 PID1 BDNF QKI ZCCHC2 CDC42EP2 PLEKHA1 PRPF38A C8orf58 ARL8B CDC42 TGFBR3 OTUD4 NFATC3 SCARF1 ATF7IP2 PPM1D LRRFIP2 C12orf76 KCNAB1 SEMA6D UBR3 LATS2 CHRNE PLXNA2 C1orf21 BTG2 PBX3 RNF144B TMEM74B LUZP1 RNF125 LITAF BFAR DACH1 ZMYM6 MED26 ADRB2 AKT3 WNT3A SETD3 CNN1 SLC7A2 KDSR MAP2K3 AGO4 DUSP3 TLE4 EXOC3L2 SRSF5 PPP6R3 RUNX1T1 MGAT4A CADM1 CDS2 RECK CCND2 CAPZA2 SMAD7 PPP2R5C KBTBD4 N4BP1 PAFAH1B1 CRIM1 BACE1 TLL1 RASL12 RASGEF1B ACTR2 SIAH1 PIAS1 USP25 PDK4 MOB4 CREBRF SCN4B RYBP PDIK1L SGK1 COPS2 PPP6C VAT1 GLUD1 FERMT2 BAG5 PIK3R1 KLHL18 PCGF5 COBLL1 EGLN2 CASZ1 DEDD SNRK ACSL1 SPRY4 CDK17 CALM1 CD164 CHORDC1 CHPT1 STXBP3 DCAF5 ABHD13 CDC37L1 CBFA2T3 C16orf72 PCDH17 PIM1 CSDE1 PHF19 PLA2G15 PHLPP2 HELZ PITPNA RNF138 MOB3B SESN1 FGF2 PDLIM5	down	*
GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION	0.0037404	0.0345249	0.4317077	-0.2232274	-1.298642	387	SMAD6 SEMA6A RASIP1 HHEX IL1B FABP4 FBP1 PID1 ENG INPP5K CAV1 CORO1C MYADM CTDSP1 HMGCR PRKAR1A CBL TRIB1 HEG1 RHOA MIR146A SH2B3 DNAJC3 FBXO7 FOXA2 LATS2 PPP1R15B HSPB1 RANBP9 HIPK3 PAQR3 SIRPA RB1 SFRP1 SPRY2 HNRNPU MAPK8IP1 PDE4D ADARB1 ARRB1 ITPRIP DUSP3 FOXO1 KLF4 CEBPA SOCS5 CDKN1A PTPRC ATF3 C9orf72 TLR4 MIR24-2 UBE2B PER1 DUSP1 SMAD7 INHBA PINK1 PPP2R5A GNAQ UBASH3B PAFAH1B1 CALM2 PKIG PPP2CA RNF149 PSEN1 SOCS3 JUN SH3BP5 DNAJA1 DUSP8 RAPGEF1 IPO7 GMFG RASSF2 GPRC5A PPM1F SPRY4 CALM1 PKIA CHORDC1 TGFB1 PARD6A SMCR8 PDE12 NLRP6 DUSP5 CBFA2T3 IRS2 TERF2IP MYOCD RGS2 KAT2B DBNDD2 ANKLE2 LDLRAD4 ARRB2 PP2D1 CDKN1C IPO5 GPD1L ADORA2A TIMP3 PAK2 PTEN DUSP7 SAMSN1 ITCH	down	*
RYTTCCTG_ETS2_B	0.0001920	0.0033264	0.5188481	-0.2060342	-1.298456	925	GPD1 GPATCH11 CLEC1B SLPI TMEM100 NOVA2 SOSTDC1 CD101 PDLIM2 DLC1 HHEX KCNA2 ROBO4 RBMS2 GAPT USHBP1 GPR65 ADCY4 MIR22HG RAMP2 BMP2 CDH5 BDNF LYL1 ARHGEF15 MMRN1 HCAR2 TMOD3 CTSW CCDC88A LDB2 CITED2 FOSL1 CALCRL ESAM PLEKHA1 CLEC10A ARL8B STX11 MARCO NEDD9 NCF2 IL1RN TGFBR2 TRIB1 IL23A FGR ZEB2 ERG SH2B3 CD5 HBEGF RILP CHMP1B PLXNA2 CLEC7A TMEM204 CLEC14A PICALM NLK FOXP1 ZNF410 MS4A1 LCP1 DES GATA3 MED26 CD93 CRK TFEC SRGN ARHGEF2 SPI1 PDE4D MYCT1 FBXL5 EXOSC9 IL10 CSRNP1 PTGIR MOAP1 SPNS3 CASKIN2 MEFV NOSTRIN LIN7C TCP11L2 ID3 KLF9 VASP DENND3 CLDN5 GRK5 MPL SSH1 ATL3 MGAT4A NFKB1 CDKN1A ST7L PTPRC M6PR XCL2 UBE2B PRF1 FCER1G PER1 ELK3 ELMSAN1 PPP2R5C SH2D2A VAMP5 PRICKLE2 ZNF706 IL7R PAFAH1B1 CALM2 MIR17HG AFF1 IL24 TLL1 CMTM6 CNRIP1 PTH1R ARHGDIB ACTR2 FOXN3 MYLIP RBPJ MYO1C ARL6IP5 ETF1 S1PR4 HCAR3 CNTF FLT1 CREM SGK1 CTSS AQP3 HCST STAT4 ZFP91 NSMCE2 ETS1 MAP4K4 CNTN4 TYROBP ELP5 JUNB RHOJ DHX15 IPO7 SP3 PIK3R1 GPR183 CDK2AP2 STX5 GRIA1 MSANTD2 TPP2 CAP1 PRKACA SNX22 RALB TAGLN2 EPC2 WDFY4 FGFR4 ESPNL TNFSF13 HIVEP2 RBKS RUNX3 FOXO3 TREX1 KLRC2 RIN2 CCR4 STRN DCK TGIF1 CD6 SBF2 CD86 ATXN1 CCR1 GPR18 VPS39 ZNF296 ADAM10 TMA7 PRICKLE4 MBNL1 GTF2B CCL20 AMD1 RNF138 IL18RAP LAT ARPC2 ZNF143 EGFL7 ADAMTS4 SF1 VGF ELOVL1 NT5C2 ARRB2 SPIB PIP4K2A TAB2 DIXDC1 ACTB SLC2A9 HNRNPK EPHA2 SSH2 OSER1 CD19 STK4 ZDHHC5 PTEN LTBP3 RORA FAM13C TOMM5 DOCK4 TRAPPC11 GRB10 EMC3 PUM1 CNN2	down	**
GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY	0.0004044	0.0062155	0.4984931	-0.2064363	-1.297921	856	SMAD6 TRIM71 ANGPT4 SEMA6A EREG TMEM100 ACVRL1 SOSTDC1 TEK HHEX SFRP4 IL1B TIE1 WNT4 GREM2 RAPGEF2 PTPRE BMPER PID1 BMP2 CDH5 ENG KL BDNF FOLR1 FYN INPP5K CAV1 BAIAP2 CITED2 CDH13 BMPR2 PLEKHA1 RBM14 FGF10 ELMO1 CDC42 TGFBR3 NCF2 GAS6 CBL TGFBR2 CD8A FGR RHOA TXNIP SH2D6 APOD TMPRSS6 MIR146A MMRN2 SH2B3 LTBP4 HBEGF ADAM17 LIFR RASGRP4 TMEM204 ITGA5 HSPB1 NLK FZD4 CAV2 ADIPOR1 GATA3 ADRB2 NDEL1 CRK SFRP1 SPTBN1 SPRY2 ZFYVE16 ZEB1 UBE2D3 ATP6V1H PDGFA RAB14 ATP6V1B2 FOXC2 NODAL TIPARP PTPN12 ROCK2 CSRNP1 PRDM16 STAT5A PTGIR DUSP3 FOXO1 SDCBP SORBS1 NPNT PLAUR ZNF423 ROCK1 DAB2 ZFAND5 MVB12B THBS1 SOCS2 ATP6V1D CLDN5 SOCS5 SIK2 EPGN VIM AXL ATP6V0D2 IGFBP2 CEP57 ACTR3 EPS15 PIK3C2A SMAD7 INHBA CUL5 MATK SH2D2A UBASH3B VEPH1 NUS1 GNAI2 HES1 HTRA4 MIR17HG CRIM1 ACTR2 TGFB2 HCK NRROS NCKAP1L PDK4 CD8B KANK1 RBPJ MYO1C FLT1 AREG WASF2 PSEN1 SOCS3 ADAMTSL2 APPL1 MAGI2 JUN NOTCH1 LTBP2 BMP3 ATP6V0B SHOC2 RAPGEF1 FERMT2 SKIL PIK3R1 DDX5 GRB2 CREB1 NPR1 CD7 FSTL3 RASSF2 APH1B GPRC5A NDST1 FGFR4 FOS SPRY4 ATP6V0D1 RHOQ UBB KLB FOXO3 EPHA3 SORT1 TGFB1 PARD6A VAV3 ZFYVE9 TGFB1I1 ATP6V1A LRRC32 IRS2 ATP6V0C DOK2 MYOCD TOB1 NPTN LTBP1 SMAD2 LDLRAD4 FGF2 ARPC2 FKBP1A EPN2 ARRB2 RTN4 TIAM1 CDKN1C HSP90AA1 DACT2 EPHA4 UBE2D1 ACTB EPHA2 CREBBP MBD5 SRMS STAM2 ING2 RET GTF2F2 KIT ARPC5 PAK2 ETV2 PTEN SKI LTBP3 FGFR1 NRP2 NRG1 CCND3 GRB10 IQGAP1 SMAD4 FLT4 SKOR1 HNRNPH1 ARHGEF18 ABI1 SETX CYBA ATP6V0A1 KALRN ACVR1C EGR1 GREM1	down	**
GO_NUCLEOLUS	0.0029258	0.0285811	0.4317077	0.2559573	1.297643	777	CPS1 MNX1 CA9 DDX11 SPATA24 HJURP MCM10 NEK2 COIL DOC2A DROSHA UBE2T STOX1 NOVA1 METTL1 CDK4 E2F8 NOL12 TRAIP DGCR8 CDCA8 SIX1 PAK6 KNOP1 TYMS DTL SMUG1 CDK5RAP3 NUB1 BTRC NLE1 FOXA1 SDHA MKI67 HLTF FBXW9 EEF1E1 TOP2A EME1 WDR3 MYO10 ITGB4 SLC29A2 CD2AP CENPW PRKDC RBM28 NSUN2 ZNF146 FANCD2 EMG1 ANG LETMD1 NEK11 GET4 ORC6 CC2D1A FBL XRCC1 PIH1D1 MDM2 RPAP2 PRMT6 SPC24 PKMYT1 BLM PML HOXB5 NOL3 GLE1 TULP3 ZNF346 SKP2 PARP1 PES1 DDX56 GEMIN4 NUSAP1 DDX51 CBX5 KRT18 PPM1E STON2 DNTTIP1 EXOSC2 CENPH POLR3K NPM3 DHX37 SNAPC1 KIF2A DHX33 TRIM41 SDCBP2 NARF PDK1 FEN1 POLR1C NF1 SAPCD2 OARD1 SF3B3 NOP2 KCTD1 MAD2L2 CENPP ITPR3 PA2G4 ZNF692 EIF6 L3MBTL3 POLR2H GOLGA3 ZNF354A FANCG PELP1 ILF2 PLEKHM1 PDCD11 FHIT HDHD3 S100A16 ARHGAP32 COG7 SSRP1 ARL6IP4 ADAR MYBBP1A METTL22 NUDT16 ZNF300 TCEA1 KIF20B KRI1 NOC2L LRWD1 PRMT7 TSEN54 S100A13 FAM207A COX10 ENC1 IP6K2 CCDC137 ETV4 BAZ2A TIMM13 GTF3C1 CKAP5 CHCHD1 ZCCHC17 RRP9 POP7 ALKBH4 ZNF202 NOL6 TBCA RPL7L1 RAI14 SRPK2 UTP20 NOC4L SURF2 HEATR1 CD2BP2 ANKRD1 DDX23 C1orf109 URB1 TMUB1 AATF DNAJC21 EXOSC5 ESRRA POLR2I ETV6 RPP38 RSPH4A MED27 STK35 RRP36 ZNF274 DDX55 TSR1 GTPBP10 KLHL7 CEP85 ZNF622 MCRS1 MAP3K14 SMARCA4 TRERF1 DDX54 ICK INO80E BMS1 MLLT1 LLPH CHD3 RBM19 CIAPIN1 SMC2 POLR1B PNKP RNF213 XPC POLR1A FBLIM1 DDX52 POP4 TP53 APEX1 MRPS27 TBL3 ADARB2 UBTF PWP1 SMARCB1 RRS1 NAT10 PTPN13 BRIX1 FTSJ3 ACSL5 IFI16 ACIN1 GEMIN2 PARP2 INO80B ZNF554 XPO6 RCN2 RPL23A MRTO4 WDR55 MUS81	up	*
PHONG_TNF_RESPONSE_NOT_VIA_P38	0.0038277	0.0351026	0.4317077	-0.2264853	-1.295188	308	TUBD1 FOXF1 DENND5A PPARG GATA2 LPXN RAPGEF2 BCL2A1 TRIB1 IER2 DNAJC3 TMEM204 KLF6 MALL SLC25A37 SRGN TCF7L2 CD58 ADARB1 MAP2K3 ARRB1 PLAUR GCHFR DRAM1 ADAMTS9 GRK5 KLF7 NFKB1 CADM1 ID2 CLK4 WDR48 DSE HES1 SERTAD2 MYO1C SGK1 C2CD2 JUN ETS1 RAC2 HSPA1B IFNGR1 JAK1 DUSP8 RCAN1 WTAP CD83 N4BP3 UVRAG TNFRSF9 DLEU2 FSTL3 TNFRSF10B GPRC5A GFPT2 PELI1 HIVEP2 ING3 EHD1 GSAP NR2C1 GNAI1 NAB1 IRS2 SOD2 PHF11 GATA6 ZNF267 ETS2 JUND GEM ICAM1 ANKLE2 PDLIM5 LAT TNFAIP8 NBN IER5 CDC42EP3 RIPK2 SP100 MEGF9 EPHA2 TRAF1 FDX1 NFKBIA PDE4A MTUS1 MMD LDLR NRP2 DOCK4 IRF2 FNBP1 CSF2 HTRA2 CD70 SERPINE1 CDKN1B BHLHE41	down	*
GO_POSITIVE_REGULATION_OF_MAPK_CASCADE	0.0040352	0.0364190	0.4070179	-0.2208115	-1.295049	426	FFAR4 HCRTR1 RAMP3 IL1A SASH1 TEK SCIMP GLIPR2 IL1B P2RY1 RAPGEF2 BMPER BMP2 KL CD44 CCL3L1 C5AR1 HMGCR FGF10 CDC42 MIR27B MARCO IL1RN GAS6 ZEB2 AVPI1 CD36 RAP1A MAP3K8 FZD4 CAV2 ADRB2 TRAF6 LAMTOR3 CRK SPRY2 MAPK8IP1 PDGFA NODAL SORBS3 MAP2K3 ROCK2 ARRB1 CCL22 SDCBP NPNT ROCK1 THBS1 SPAG9 PDE8A CCL3 PTPRC EPGN IRAK2 CCL4 TLR4 MIR24-2 XCL2 PIK3R5 GNAI2 TGFB2 ARL6IP5 FLT1 IL6 DNAJC27 PSEN1 JUN NOTCH1 ADRA1A PDE5A RAPGEF1 CCR7 ACKR3 PRKCE GPR183 OSM RASSF2 NDST1 FGFR4 GPR37L1 UBB KLB CD74 TIMP2 TGFB1 PEA15 FPR2 MIR23A SH3RF3 DUSP5 MAP3K2 RELL1 CD81 NQO2 CCR1 NPTN CCL20 ICAM1 FGF2 ARRB2 TIAM1 CXCR4 EPHA4 TAB2 RIPK2 HAVCR2 MAP3K4 RET KIT EDN1 PTEN DUSP7 FGFR1 NRG1 IQGAP1 BANK1 FLT4 SPHK1 UBE2V1 CDON C5AR2 GHR DUSP6 C5 MAPK1 TREM2 NCF1 RB1CC1 FPR1 PIK3CG MUL1 WNT5A MAP4K2 UBE2N KIDINS220 AKAP12 GPR55 HMGB1 PDE6G	down	*
RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	0.0010541	0.0132393	0.4550599	-0.2077631	-1.294689	706	SLPI SIDT2 SASH1 EDNRB SECISBP2L HHEX GLIPR2 ATXN3 CAT HSD17B6 LRRFIP1 PTPRB PID1 FOLR1 CD44 TXNL1 CITED2 ELF2 INPP5A MTMR10 FBXO3 TGFBR3 NEDD9 PDE4C TSHZ1 ZBTB2 TGFBR2 TEX2 ZEB2 SNHG5 TXNIP ZBTB4 MMRN2 FBXO7 UBL3 MALAT1 PCYOX1 LIFR RAP1A CSRP1 ZDHHC2 RNF144B ABCG1 FOXP1 HIPK3 KLF6 GPBP1L1 CLN5 PPP2R2A SLAIN2 TNS1 AKT3 SPTBN1 PPP1R13B EPM2AIP1 UBE2D3 CST3 CYBRD1 CSRNP1 SNED1 PER3 AGO3 FOXO1 DENND6A TSPAN12 FAM76A HAUS2 ANKRD10 THBS1 MED6 SOCS2 EPM2A TMBIM1 FMNL3 NR1D2 TEF CD302 PNRC1 RECK LBH CCND2 WASF3 NUTM2A-AS1 PINK1 MATN2 PRICKLE2 KBTBD4 HES1 TBC1D4 ADD1 MRVI1 PIAS1 KANK1 MYLIP SLC25A3 MED28 SGK1 PHACTR2 SNAP23 RNF141 MAGI2 TMTC1 JUN LIMD1 KCTD12 LTBP2 DDX17 BTD APBB2 PTGER4 PODXL BAG5 SUGT1P3 SELENBP1 HERC1 SNX1 MSANTD2 GPRC5A SNRK WDR7 TOM1L2 RNF146 HIVEP2 MBP CD74 MARC2 CCDC152 TCF4 NDUFA5 KCTD10 TSC22D1 TPMT RELL1 ATXN1 PHF11 TOB1 STX12 SBSPON N4BP2L2 KAT2B TAGLN MBNL1 INO80D PITPNA JUND RBL2 MOB3B SESN1 GPX3 PDLIM5 CPQ TNFAIP8 EPB41L5 OPN3 SEC63 B3GALNT1 EPHA4 TAB2 FBXO30 SIK3 TOB2 ALDH2 TBC1D1 FBXO25 ACACB GPD1L BCAM RBMS3 METTL7A GLUL LIMCH1 CUL3 NFKBIA CCDC92 RNF38 ST6GAL2 PTEN LTBP3 CYTH1 ABCA8 TMCC3 HEBP1 GSPT1 EHD4 ENY2 SMAD4 SPATA13 RAP1GAP PPP1CB FNBP1 MED31 CBX7	down	*
DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN	0.0036351	0.0338035	0.4317077	-0.2179911	-1.294527	464	EPAS1 SLC31A2 SASH1 PPARG CD55 GLIPR2 CPEB2 RAPGEF2 MBOAT2 PLEKHF2 KIAA1109 MYADM NEDD4L CITED2 QKI YPEL5 NEDD9 NCF2 SLCO2A1 TGFBR2 TRIB1 RFTN1 WWC2 ATP2B1 SGMS2 TACC1 PPP1R15B ABCG2 CSRP1 BTG2 MAP3K8 RNF144B ABCG1 KLF6 CLK1 ITSN2 HERC3 MCL1 PPP3CC EPB41L2 PTPN12 ROCK2 CSRNP1 SYNPO EPOR KIAA0513 TCP11L2 TSPAN12 ACSL3 COQ10B ID3 DAB2 USP2 DRAM1 SOCS2 MYO1B FAM49B MGAT4A RIT1 CDKN1A RBMS1 PNRC1 DUSP1 PINK1 DSE MATN2 HES1 ANXA3 CRIM1 LMBRD1 TGFB2 CLN8 CREBRF PHACTR2 AQP3 CYB5R1 JUN CPEB4 PDE5A MSRB3 MAP4K4 JUNB IFNGR1 RCAN1 PTGER4 FERMT2 SKIL PNPLA8 ACKR3 N4BP3 COBLL1 LPCAT2 TOM1L2 LMCD1 YPEL2 HIVEP2 MYL12A MME AKIRIN2 GSAP SERPINB1 BAZ2B PDLIM1 HBP1 STON1 KYNU GATA6 NBEAL1 KAT2B TCF7L1 TAGLN UNC13D ARAP2 LDLRAD4 PDLIM5 EPB41L5 TFPI IER5 EPHA4 RND1 BOK STAM2 LYSMD3 LIMCH1	down	*
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN	0.0038713	0.0354015	0.4317077	0.2569982	1.294468	662	HMGA2 TRIP13 FOXM1 HELLS HJURP DEPTOR COIL TIMELESS PAGR1 PBK TBRG4 BET1 SPDEF CDCA7 C12orf66 METTL1 GPR35 TUBB2B AGFG2 POLE DGCR8 YEATS4 ALDH18A1 CDC6 SLC4A3 SFXN1 TRIB3 FIGNL1 MCM2 TYMS DTX3 DTL LIG3 RCCD1 COQ3 FAM220A C5orf34 POLR3A GOLPH3 GFPT1 F2RL1 TPBG BRAT1 EEF1E1 RFXANK CBX3 PSENEN SLC29A2 POLD2 IRF3 CD2AP MDFI MRPL3 TOM1L1 MCCC2 TARS2 SMYD5 PSMG4 STEAP4 DCTPP1 MGA GRHL2 ALG3 SLC25A10 HSPBP1 PIGO SKP2 THOP1 IKBKB NCAPG2 URI1 SLC39A11 OSMR PABPN1 SSBP1 EXOSC2 PHF12 GMNN GDPD1 VANGL2 SLC25A13 GNPNAT1 KRBA1 CPNE1 MTBP CBX1 MAD2L2 VPS72 ACVR1B CPT1B KPNB1 ACBD6 PELP1 INTS7 POFUT1 C19orf44 TRIM16 CNOT2 ADAT1 FNDC4 LMNB2 DHODH DUSP12 LMF1 TK1 DTYMK DBN1 MYBBP1A IL15RA METTL22 XPR1 KRI1 TMEM186 ZNF768 TWF1 POLD1 MAGOHB JTB POLB ENC1 MARCKSL1 ELAC2 GEMIN6 BRD8 AP3M2 PHYKPL FANCM C16orf58 RAI14 PIGU BTN1A1 HEATR1 TDP1 TFAP4 LANCL2 SLC35A3 SRSF1 RAB3D AATF ADCK1 NEURL4 EXOSC5 POLR2I SUOX CEP152 TCERG1 KLHL7 BCL9 ZNF212 DCPS GTPBP2 ICK CDK5RAP1 WDR4 CCDC9 WDR77 PRPF31 FARSB TRIP4 ZNF292 FBXW11 ARHGAP5 ZSCAN22 NUDT16L1 POMK CTTN PTPRF ERBB2 UBAP2L ZNF142 GNA12 FAIM POLR1B LOXL4 TCF3 POLR1A DTNBP1 DNAJC14 EARS2 SRPRB PAICS TIMM44 APEX1 BPNT1 PNN CDKAL1 NELFA DNM1L TRUB2 COX17 TMEM161A C12orf10 ERLIN1 ACIN1 CYB5B PARP2	up	*
GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION	0.0007563	0.0102200	0.4772708	-0.2129454	-1.294301	589	FFAR4 RBP4 RAB11FIP1 SIDT2 IL17RB IL1A FCN1 ADTRP IL1B SLC51B NUP54 INSIG1 FYN LPL HCAR2 INPP5K BAG4 VAMP2 HMGCR CDC42 IL1RL1 GAS6 CD22 FGR NUMB EDEM1 APOD CD36 ANXA1 MIR146A CNST CARD16 CD33 CACNA2D2 FOXA2 RAPGEF4 RAP1A ANXA5 ABCG1 FOXP1 SLC7A11 LCP1 STOM GATA3 PPP3CA RGCC TRAF6 NDEL1 SFRP1 SPTBN1 PPP1R13B CRTAM SRGN TCF7L2 UBE2D3 TXN CD58 PPP3CC IL10 ARRB1 CASP1 ACSL3 REST ARNTL KLF7 GAPVD1 MYRIP CTSD CCL3 DPH3 PER2 CADM1 TLR4 ARC MIR24-2 FRMD4A CPT1A CLEC9A PINK1 RUFY3 TP53BP2 TGFB2 SNX3 KCNA5 PKIG MYO1C IL6 DNAJC27 SAR1A CD160 PSEN1 GLUD1 RAC2 CARD8 PLK3 DNAJA1 IFNGR1 PTGER4 CCR7 PIK3R1 UBAC2 PRKCE OSM GRASP RAB8A UNC13B RBM22 PRKACA TCP1 YWHAZ PPM1F CD34 MBP MAPK8 PKIA CHIA TGFB1 PARD6A SERPINB1 LRRC32 APBB1 PIK3C3 IRS2 PPP3R1 CD81 EXOC1 ORM2 CSNK2A2 PPID SYT11 BNIP3L PCM1 EPB41L5 TIAM1 RIPK2 NLRP3 HSPA8 SP100 HAVCR2 IPO5 SREBF2 GLUL TLR10 RAPGEF3 ADORA2A AIM2 PSMD9 ENY2 BANK1 PMAIP1 PIM3 DISP1 HTRA2 ACVR1C CHP1 C5AR2 EXPH5 TMEM30A KCNE1 FKBP1B CLEC4E C5 MAPK1 CLOCK MYH10 TREM2 SH3GLB1	down	*
GRHL1_TARGET_GENES	0.0003553	0.0056300	0.4984931	0.2519265	1.293533	1271	ATP10B SYT8 MUC13 IGSF9 PKP2 CDC45 BDH1 EPN3 NGEF RBBP8NL ZMYND8 NUP107 NEK2 COIL CENPF COA1 SEMA4B PSPH GGCT KIF18B TTC25 PHF14 TSFM CREB3L4 ZNF138 TUBB2B TMC1 C6orf141 RACGAP1 UBE2Z NOL12 NAALADL2 EIF2B5 SEC14L5 NUF2 CDCA8 AURKB ECT2 RBBP8 XPNPEP1 PMS2 APOL2 TMCC1-AS1 CIB1 TMCC1 COPB2 CCT6A KIAA0895 PDE9A RCCD1 DZANK1 MYL6B CDK5RAP3 SPDL1 UQCC1 NUB1 KAZALD1 FAM220A SYT12 NME1 WDR62 MIR4458HG BZW2 EXO1 RAB11B-AS1 STAP2 RNF216P1 KNTC1 CLHC1 EXOC4 RPL32P3 CENPL EME1 IQCD WDR3 NDUFS2 MYO10 C1orf226 SAE1 SFI1 E2F2 CENPW WDR78 COASY TPCN1 MMS22L RNF43 AKAP1 SETDB1 RAD54L ERAL1 PKM MRPL27 ANKMY1 MCM3 ZNF226 LINC00511 MCCC2 AIMP2 TARS2 L3HYPDH SLC2A11 RNFT2 PSMG4 OAZ3 SIDT1 PEX26 MAD2L1 NFYA DCTPP1 MDM2 SPC24 AKT2 SPATA17 EHF C6orf223 DDR1 FDXR FBXL19 PHB DET1 NIPAL1 PARD3 SRRM5 TULP3 CNPY2 MYO1A RECQL5 ZCRB1 RNF216 CDKN2C PPIL2 SUPT5H ING4 WDR5B MCTP2 EXOSC2 CCT3 ABHD17C C1orf112 PHF12 TNK2 RBCK1 POC5 ITGB8 VPS28 SLC16A13 TRIM2 ZNF815P PSMB5 STAT2 GJB3 SEC61G PMEL RNF181 SDCBP2 PSAT1 ANKRD26 ANAPC7 EGF LINC00649 THAP8 OARD1 TTI1 ETFB LCA5 MYO5B AK7 MTBP SNRPE GOLGA5 NLN NOP2 PSMC4 CASC1 ZKSCAN5 C9orf43 PA2G4 UBN2 ZNF692 RANGAP1 PYROXD2 POLR2H ACBD6 CCDC142 ATP7B DCAKD NEK10 SEC16B VPS41 CNOT2 PSMA5 ALDH7A1 MLF2 UROS ARHGAP32 CCDC151 PLEKHG3 PIGG GPRC5C MRPL11 USB1 MORN2 DPH2 KCNC3 TMTC2 RHBDD3 SOX2-OT CCDC146 IQCK ANP32E RNF224 ACAD10 ZSWIM1 TMEM186 CCDC51 KRT19 C15orf41 IQCH THRB LTBR FAM200A CEP128 CCDC159 ATAD5 ATP13A1 IP6K2 ARHGAP12 GEMIN6 EFCAB7 GTF3C1 LIMA1 PPHLN1 L3MBTL2 DGKA RPRD1B CENPM ANKRD6 ERBB3 MAN2A1 EFHC1 FAF1 POP7 ASCC1 ACLY PPP1R3D CHMP4C ABCC3 CDK5RAP2 KRT8 ODF2L MGME1 ZNF160 BLCAP MRPS33 ANKIB1 METTL2B ZNF446 WDR83 RPL7L1 DHX8 NOSIP CD2BP2 MRPL53 SLC35A3 SCYL3 HAX1 C1orf109 FBXO36 URB1 SNX11 NEURL4 DUS4L OVOL2 SLC1A5 RPP38 SMARCC2 ANK3 ALG8 CEP85 SUV39H2 NME1-NME2 PMS1 ZNF224 RPS26 RRNAD1 NCDN ULK4 HDLBP CISD3 BANF1 POLR3B RNF121 PAK4 TTC31 CCDC9 PRPF31 ARRDC1 BMS1 FARSB ZNF384 TRIP4 ZWILCH FBXW11 PFKM KCTD21-AS1 SCOC ZNF700 NLGN2 MRPL9 TYSND1 TRAK1 KIAA0825 NME7 LINC00240 AGBL5 TMEM101 MXD3 AURKAIP1 SNUPN VDAC3 UQCRQ ZNF131 BCL6 GOSR1 ANKMY2 CLNK CGN CELSR3 FRMD6 RAB25 NMT1 GDPGP1 NEIL1 PAICS TMEM256 ZNF526 MRPS27 TBL3 PNN TTC9C KRT80 FAM185A ULBP3 SART1 TMEM38A RAD1 MRPL48 NDUFB7 RRS1 NLGN1 STK11IP C4orf46 CLASP1 FAM222B THRB-AS1 MOK SART3 HEMK1 BRIX1 ZNF33A C12orf10 MSANTD4 ZNF629 RPUSD3 CLNS1A TTC5 TFB1M FAM47E TOMM7 ZSWIM5 TMEM62 EIF2D METTL18 DHX57 EID2 ZNF319 SETD1A ZDHHC1 RNF126 BMF DEPDC4 MRPS16 ACSM3 EGOT TOP3A ITGB5 KLHL42	up	**
DBP_TARGET_GENES	0.0006238	0.0088215	0.4772708	0.2523752	1.293179	1215	ATP10B TSPAN8 TRIP13 HS3ST1 SPATA24 C1GALT1 DDX12P HJURP FAM81A PKP2 CDC45 TICRR PARPBP RPGRIP1L CHEK2 S100A2 BUB1B NUP107 XYLB ZNF12 DROSHA TIMELESS HOXB6 COA1 PSPH GGCT CHCHD6 BET1 MRPL46 CDK4 SMPD3 RACGAP1 HILPDA NABP2 EIF2B5 AP1S1 TTC26 SAP30L-AS1 NUF2 CCNB2 BCL2L14 PRC1 EIF3B CCT6A PIP4K2C KIAA0895 ZNF3 CAND1 NCAPD2 DZANK1 INTS1 LSM5 FAM220A NME1 BTRC RAB11B-AS1 SMARCC1 ZNF391 KIF23 BOD1 KNTC1 RHNO1 TSGA10 TIGD4 EEF1E1 RPL32P3 TMEM184A AURKA NUP155 CBX3 NDUFS2 SAE1 RAB19 IRF3 KIF2C MAD1L1 MPHOSPH9 CPD SPEF2 RBM28 NSUN2 MORN1 ERAL1 ZNF146 LINC00511 SEC61A1 TARS2 SP140L RNFT2 LETMD1 WDR60 BRD9 SARS2 LINC00265 CHEK1 SCAMP5 AHCY RAD51AP1 TIMM50 MRPS11 BLM MRPS30 PHB SYMPK FBXO16 ALDOA DET1 STXBP4 TULP3 CCDC138 LEF1-AS1 CNPY2 PPP1R37 RECQL5 CAPN8 MEA1 PPIL2 NUSAP1 TMEM106C SUPT5H CBX5 ANAPC5 ING4 HDGF CDK12 WDR5B CEP97 LMCD1-AS1 KCTD7 MDH1B PICK1 EEPD1 C1orf112 PHF12 ATIC NPM3 ACP6 VPS28 SMG9 STEAP1 ZNF815P PSMB5 STAT2 PRR14L ANAPC7 NUP205 TMEM79 POC1B LINC00649 MRPS12 METTL3 RNF207 TTI1 TNRC18 UQCC2 NOP2 ZKSCAN5 SRD5A1 PA2G4 LZTR1 UBN2 CHCHD3 TPD52L2 RNF44 ACBD6 ZSCAN21 TSPAN17 EXOC7 VIPAS39 C19orf44 SMG5 WDR53 NDUFA11 SEC16B TAPBPL SPG7 COA3 VPS41 GALK2 TSNAXIP1 JOSD2 NMRAL1 SNRPA MNS1 AARSD1 MAN1B1 RAD9A LONP1 CCDC151 OSBPL3 KIF22 ZMAT5 TRIM37 COX7C MORN2 COPS7B FBXO4 PPOX PLEKHA8 AKAP8L MEGF8 TP53TG1 CCDC146 MRPL4 VIL1 ITFG2 CLTA TMEM186 ASNS GSTK1 SLC4A2 BCL2L12 CD27-AS1 C15orf41 CKMT2-AS1 SIL1 ENC1 AAMP YARS2 NIF3L1 SLX4IP RAD50 NR6A1 KDM3A CENPK BAZ2A CHPF SASS6 GEMIN6 KLHDC3 SH2B1 TADA3 LIMA1 L3MBTL2 DGKA RPRD1B WDR34 AAAS GBF1 BCL2L1 GMPPA PELO SRRT CDK5RAP2 KRT8 MYPOP MRPS33 ANKIB1 METTL2B RPL7L1 UBL7-AS1 MED24 TMEM147 USP21 NMNAT1 CD2BP2 SPINK5 TMEM198 LSM7 C5orf22 EIF3D SRSF1 HAX1 C1orf109 LRCH4 KATNB1 MRPL51 ETV6 WDR27 AP4B1 SH3BP5L SF3A2 DDX55 SPSB3 GTPBP10 KLHL7 FARSA CEP85 ZNF622 NME1-NME2 AMN1 RER1 MCRS1 RPS26 MAP3K14 PRDM10 ECH1 TXNL4B DOHH PCBD2 CTU1 STAT6 ABCF2 WDR4 NUBP2 TTC1 STK25 TRIP4 ZWILCH TOMM40L PPFIA3 PFKM SAMD4B TYSND1 ZSCAN22 GBP2 SNRNP200 RPRD2 CDK5 SNX8 TMEM101 FAM83E MXD3 AURKAIP1 VDAC3 ALDH3A1 C1orf159 DNAJC14 SRCAP POP4 ZMAT2 LRSAM1 FIS1 LEMD2 SLC36A1 EPHB4 FBXO45 BCAT2 NELFA SFXN5 MRPL20 SART1 ATF7IP CCDC91 NAT10 MUC1 C4orf46 TRUB2 ILVBL FAM222B SCAF1 ATG4B CALU SART3 HEMK1 FTSJ3 C12orf10 FBXL18 ANKRD11 ALKBH2 CSTF1 TPM1 INO80B CEP290 METTL18 HEXIM2 NUMBL PLAC8 DHX57 MORN4 TNFRSF1A SETD1A WDR55 SLC38A10 MUS81	up	**
MIR548AW	0.0014173	0.0164990	0.4550599	-0.2178826	-1.290329	493	PRMT8 EPAS1 GCOM1 SECISBP2L RBMS2 CLEC3B NUP54 LRRFIP1 INSIG1 GPC5 TMEM170B OTUD1 QKI BMPR2 S1PR1 MEF2A CDC42 NEDD9 VAPA EOGT USP47 CCNL1 ZEB2 STARD4 HECW2 RAP1A PPP1R15B MTF1 PLXNA2 PBX3 HIPK3 GLS MALL PEX5L SLAIN2 PLXNA4 AKT3 ITSN2 PDE4D UBE2D3 TFRC ATP6V1B2 FBXO8 AGO4 PRDM16 AHNAK SORBS1 BNIP2 KLF4 TMED5 KLF7 UBQLN1 SNIP1 RBMS1 GPR85 EPS15 WASF3 CLIP4 FAM76B NCKAP5 AKIRIN1 TLL1 CNOT6L ZDHHC20 FOXN3 TMEM9B SPIN1 CREBRF DCP1A PDIK1L PHTF2 SGK1 HCFC2 PDCD6IP PPP6C C20orf194 PDE5A BMP3 UHRF2 PIK3R1 FRYL FAM43A KBTBD8 NUDT15 HOMER1 CASZ1 CGGBP1 RHOQ PPTC7 MAPK8 TSHZ3 XYLT1 CR1 BTBD7 ING3 SPOP PBRM1 DDHD2 STRN NR2C1 DCK DPM1 VAMP4 CNOT7 HFM1 GNA13 PLAA ARPP19 INO80D HELZ PITPNA GEM MIER1 MGAT2 ACAP2 BRWD1 HNRNPK POLR2M ZDHHC21 GRIN3A KPNA4 PALD1 TBCEL FNBP4 LIMCH1 FOXJ2 PTEN B3GNT2 TMCC3 LDLR NR3C2 FAM13B GSPT1 WDFY3 PUM1 SPOPL ELFN1 PURB SMAD4 RBMXL1 MB21D2 CFL2 CHIC2 CLIP1 ENDOD1 HIPK1 ATF2 LHFPL2 CLOCK MAMDC2 CCNK KMT2E CBR4 PTGS1 CTDSPL2 EBF1 SV2B VPS36 API5 SPTY2D1 LDB3 SCAF11 MAN1A1 TES ADH1B RNF111 CNTN1 PDPN ROBO2 SREK1IP1 NEXN FNIP1 CCNC MAT2B	down	*
MIR335_3P	0.0010774	0.0134682	0.4550599	-0.2070508	-1.289914	720	CXCL3 EREG SWAP70 ABHD5 DLC1 SGK3 SOWAHC RBMS2 SLC16A12 SPN P2RY1 CLDND1 KCTD9 INSIG1 TRPC3 MMRN1 CCDC88A ST3GAL6 NEDD4L RTN3 THAP2 ZCCHC2 MTMR10 DYRK1A ELMO1 NR3C1 VAPA DSCAML1 TSHZ1 OTUD4 FAM49A ZEB2 DNAJB14 TOE1 RBM7 NCEH1 DNAJC3 TRA2B B3GNT5 UBL3 SLC36A4 SLC25A17 LIFR RAB33B TNIP3 ZBTB21 SLC7A11 ZNF697 PPP3CA ANKRD29 TMEM41B HERC3 BAG1 TIPARP CYBRD1 ROCK2 PER3 CCDC82 SGTB ADO HYPK RUNX1T1 REST PLEKHM3 TMED5 MYRIP ERP44 LRRC40 NPAS3 GPR85 CTBS ID2 ELK3 CPT1A PTCHD4 CUL5 ADAMTS8 MPC1 KIAA0408 PDE1C TBC1D4 ACTR2 ZNF426 ARL6IP5 CREBRF ETF1 ELF1 PDIK1L BCAR3 LRRTM2 DDHD1 PHACTR2 APPL1 RAB8B PIKFYVE NECAP1 TMTC1 CPEB4 GABPA ETS1 ADRA1A MSRB3 CCDC50 HSPA1B TMPRSS11D HELQ RAPGEF1 ELOVL7 ENPP4 PCGF5 COBLL1 ATL2 RC3H1 HSD17B12 RPS6KA1 TMEM167B NUDT15 HOMER1 PREX2 NAA30 WDR7 OCIAD1 MCAM AGFG1 POGLUT1 GPRIN3 FOS CALM1 NECAB1 YTHDF3 SRSF6 CCDC85A NAPG TTBK2 SPOP PBRM1 NIPA2 TCF4 STRN PDS5B FEM1B PDE12 ZCCHC10 MCUR1 PCDH17 CCDC68 GNB4 APLP2 THAP9 STON1 SBSPON RIMKLB KAT2B PHLPP2 HELZ NR2E3 RNF138 NEK1 PCM1 YAF2 CEP170 OPN3 B3GALNT1 MTO1 EPHA4 UBE2D1 NUP98 ZDHHC21 GRIN3A KPNA4 RND1 RBMS3 PARVA VSIG10 CUL3 PAK2 PTEN FAM126B PRKG1 GPR171 RORA	down	*
ZNF2_TARGET_GENES	0.0033107	0.0314887	0.4317077	0.2526944	1.288078	943	PPM1H STYK1 PTPRZ1 KIF20A GPR89A CPLX2 AK4 DNAH2 AP3B2 ABCA17P ADRA2A DOC2A PRTFDC1 C17orf75 PDCD2L STOX1 TSHZ2 TSFM SRGAP3 METTL1 GINS1 CDCA2 PCDHGA6 NOL12 SDHAP3 ANKRD24 TTC26 GRIN2A ZNF714 SPATS2 HOXB7 SPINT2 UMPS GON4L ZNF3 XPOT SMUG1 COQ3 AP1G2 CCT2 INTS1 SYT12 DNAI1 TOP3B PPP1R9A TTLL4 ARMC4 PLEKHG1 TMEM41A DNPH1 SMARCD3 MAP7 SMARCC1 FOXJ1 AP4M1 FRS2 DPY19L1 RFXANK EME1 SPTB GTPBP3 MCM7 ZNF860 IL12B MPHOSPH9 C14orf93 WIPI2 ANKRD52 RBM28 RNF157-AS1 ASPHD1 RNF43 FNDC5 AKAP1 WNT1 HOOK1 AMACR MRPL27 CMBL FANCD2 CDC25C TARS2 LETMD1 KCNJ11 FNTB SAMD10 KLHL3 SYMPK ALDOA R3HDM2 MARK1 TXLNB RNF216 CDKN2C SUPT5H C2orf50 SLC39A11 ZNF45 HDGF CDK12 LINGO1 DTD1 ZNF260 ANKRD54 GMNN NAV2 POC5 PGBD2 STEAP1 CCNJL GNPNAT1 SDCBP2 ENPP3 PEG10 KRBA1 CCDC88C TMEM79 MTBP ATAD3A RNF150 SNRPE ABCA4 ZNF827 PSMC4 ZNF623 CENPP PA2G4 IRF6 LZTR1 GIPC1 GOLGA3 SMG5 SPG7 AMPH EFCAB2 UROS C19orf12 KIF22 PIGG UBE3D ROGDI PPP1R26-AS1 TMTC2 HDAC1 URGCP MLEC IL15RA LMTK2 GEMIN5 MRPL4 LINC00662 ANP32E LRWD1 GSTK1 POLD1 FAM207A THRB FAM200A MAGOHB PRRG2 PEX10 ZBTB45 ZNF140 SLC1A3 RAB24 CABLES2 PCDHGB1 ETV4 PROX1 PFAS LSG1 BRD8 KCNB1 VPS25 AHCYL1 ERBB3 WDR34 AAAS FTCD SIRT4 KLHL32 EFHC1 C12orf65 DUS1L NRXN2 LRRC59 AP3M2 SLC6A1 ARHGAP22 PPCDC CELF4 LPCAT4 CENPT ZSWIM8 NOSIP CCSER1 CACNB3 SCYL3 GINS3 FBXO36 POLR2J3 KATNB1 IGHMBP2 RSPH4A PPP1R3E SMARCC2 DDX55 COPZ1 SPSB3 GTPBP10 GNAL NUP62 SPAG4 INTS8 PRPF18 MCRS1 ZNF212 RRNAD1 BBX BANF1 ARSA CDC42BPA DOHH DTNB STAT6 CDK5RAP1 CLUAP1 NUBP2 HOOK2 TRIP4 CHMP1A ARHGAP5 ZNF217 GTF3C5 SAMD4B MRPL21 LINC00240 TMEM101 TBCB AURKAIP1 ZNF131 SIRT6 ZNF91 TCF3 EIF4G1 SRCAP ADRM1 ADAM15 POP4 NPTX1 PDZD7 TRUB1 ZNF341 SLC36A1 TBL3 UBTF MRPL48 ZNF367 TRUB2 THRB-AS1 NELL2 C12orf10 KCTD19 SETD5 FBXL18 ANKRD13D NCAPH SLC33A1 SPATA33 BCKDK GLIPR1L1 INO80B EIF2D LASP1 ZNF511 MRTO4 ANO8 MED22 SCRN2 GLI3 MAN2C1 VPS16 PDK2 NR2F6 PTPRK TRAFD1 PARL TMEM259 RPL36 HDAC10 RBL1 APBA3 NFE2L1 USP35 RAB11FIP3 KIFAP3 NSL1 SLC4A1AP STARD10 TSC22D4 TEFM PRCC KCNK1 ABCD3 CNTNAP2 RAB26 MAP3K5 CS RAC3 GGA3 TIPIN BRD4 TTC13 CDH24 DTX4 TMEM219 RPL41 BNIP1 KMT2D KLHL17 SAP30L WDR25 SLC44A1 LRRC37B DPYSL3 ZNF30 PAWR CACNA1A PDXDC1 COQ4 CTPS1 GLCE	up	*
GO_REGULATION_OF_PEPTIDE_SECRETION	0.0037347	0.0344971	0.4317077	-0.2215053	-1.284357	372	FFAR4 RBP4 RAB11FIP1 SIDT2 IL17RB IL1A FCN1 ADTRP IL1B LPL HCAR2 HMGCR IL1RL1 GAS6 CD22 FGR ANXA1 MIR146A CARD16 CD33 CACNA2D2 FOXA2 RAPGEF4 RAP1A ANXA5 ABCG1 FOXP1 GATA3 PPP3CA RGCC TRAF6 SFRP1 SPTBN1 CRTAM SRGN TCF7L2 CD58 IL10 ARRB1 CASP1 REST ARNTL KLF7 MYRIP CCL3 DPH3 PER2 CADM1 TLR4 MIR24-2 FRMD4A CPT1A CLEC9A TGFB2 KCNA5 IL6 CD160 RAB8B GLUD1 CARD8 IFNGR1 PTGER4 CCR7 PRKCE OSM UNC13B CD34 MBP CD74 CHIA TGFB1 PARD6A SERPINB1 LRRC32 APBB1 PIK3C3 IRS2 EXOC1 ORM2 PPID SYT11 TIAM1 RIPK2 NLRP3 HAVCR2 GLUL TLR10 RAPGEF3 ADORA2A AIM2 PSMD9 ENY2 BANK1 PIM3 DISP1 KALRN ACVR1C C5AR2 EXPH5 FKBP1B CLEC4E C5 CLOCK MYH10 TREM2 S100A8	down	*
MIR506_3P	0.0009569	0.0122957	0.4772708	-0.2070361	-1.283820	663	RAB11FIP1 SLC31A2 SEMA6A ABHD5 EDNRB OSBPL11 ADCY9 MBOAT2 CLDND1 RCOR1 EGR2 PLEKHF2 RGS9 CAV1 MYADM THAP2 QKI SLC25A30 MTMR10 CTDSP1 MEF2A TSHZ1 CBL GGA2 CASP9 EDEM1 SEMA6D SH2B3 NFIX TTL CYB5A ZNF503 ANXA5 FZD4 LITAF HIPK3 KLF6 LCP1 STOM NR4A1 MED26 SLC25A37 AKT3 PTPN12 EFCAB14 AMOTL1 DUSP3 LRRC57 DENND6A LIMS1 ZCCHC24 PLEKHM3 ROCK1 USP2 TNFSF15 CEBPA MYRIP KIF26A ABCC4 SNIP1 TMBIM1 SSH1 ATL3 MGAT4A RBMS1 VIM TADA2B C9orf72 JAM2 PIK3C2A ELK3 WDR48 ZMPSTE24 CPT1A CUL5 ILDR2 ZNF706 MYH11 FKBP15 KPNA3 TLL1 LMBRD1 RSRC2 C2orf69 SERTAD2 KANK1 MYLIP MYO1C CREBRF VAMP3 GZF1 WASF2 SGK1 PHACTR2 UBQLN3 ARL5B MITF VAT1 ETS1 DNASE2 RHOG APBB2 RAPGEF1 WTAP FERMT2 ENPP4 EEA1 PI4K2B GRB2 MAPK4 RPS6KA1 SLC10A7 FAM177A1 THSD7B GFPT2 PPM1F ACSL1 BLOC1S6 CD151 POGLUT1 ADNP2 RHOQ PNPLA2 CD164 HIVEP2 ECI2 SRSF6 XYLT1 NAP1L5 CPA3 EPHA3 TFEB PEA15 ZBTB11 GNAI1 MCUR1 MAP3K2 PIM1 ORC2 PHF19 GATA6 PDE4B RXRA ANKLE2 PDLIM5 SLC31A1 PUS10 DCTN4 TMEM184B RBMS3 ULK2 TMEM109 KLLN KATNA1 LIMCH1 BCAT1 RASSF8 SNAP29 PRKG1 ANXA11 NR3C2 NAA15 IQGAP1 WDFY3 SPOPL ENY2 SLC44A5 EVI5 PAPSS2 GPALPP1 FNBP1 REEP1 SUGT1 EGR1 CHP1 CDON CHIC2 SLC25A38 SPPL2A SVIL KCNJ6 ENDOD1 HIPK1 USP30 CLOCK MYH10 ITGB1	down	*
MIR23A_3P_MIR23B_3P	0.0015426	0.0176171	0.4550599	-0.2159220	-1.283525	489	WEE1 EPAS1 TRHDE SOWAHC ZC3H12C CPEB2 PTPRB TTC7B RCOR1 ZBTB34 MED4 KIAA1109 NEDD4L CALCRL ZCCHC2 ELF2 INPP5A ARL8B MEF2A RXFP1 WBP4 LAMP1 AGPAT4 ZBTB2 TGFBR2 TRIB1 C12orf76 SEMA6D RAP1A MTF1 SWT1 ECHDC1 SERINC1 NLK GLS CAMTA1 ZEB1 MYCT1 TMEM38B SCP2 CLEC1A BNIP2 PPM1K TJP1 TMED5 GRK5 CDS2 PNRC1 ZBTB43 N4BP1 VEPH1 NUS1 CNOT6L VCPKMT NCOA1 C2orf69 LIN54 TMOD1 CDC40 PKNOX1 NEK7 MAML2 RAB8B PRPH2 SEC14L1 DDX47 MITF PNMA2 CARD8 MAP4K4 TBC1D12 PTGER4 DHX15 SDHD PRKCE GTDC1 DENND4A CGGBP1 CELF2 GAS2L3 CDK17 FOSB PKIA NAA16 NAP1L5 STRN NDUFA5 TGIF1 TEX30 CBFA2T3 ATXN1 MEIS1 WBP2 STX12 MICU3 ZNF267 PDE4B CCNH BNIP3L FGF2 INTS6 RPP30 SFT2D1 ORMDL1 TMOD2 UBE2D1 IPO5 FBXO25 MEX3C BRWD1 G3BP2 SSH2 KPNA4 STK4 CUL3 JMJD1C RNF38 PAK2 PTEN FAM126B CAMSAP2 RORA MT2A TLK1 SPOPL CNN2 ZBTB44 SNRPG MAP4 REEP1	down	*
GO_METAL_ION_HOMEOSTASIS	0.0019242	0.0208037	0.4550599	-0.2152523	-1.280227	504	SLC24A4 EPAS1 HCRTR1 GPR17 SLC31A2 RAMP3 CD52 HMOX1 SWAP70 SLC12A6 MCOLN1 EDNRB CD55 GATA2 F2RL3 SNX10 P2RY1 GPR65 CDH5 KL TRPC3 FYN JPH4 CCRL2 CAV1 NEDD4L ADRA1D GTF2I SLC39A8 ADCYAP1R1 TBXA2R C5AR1 S1PR1 CYP4A11 SLC11A1 CD36 JPH2 TMPRSS6 ATP2B1 KCNK3 ABCG2 PICALM ANXA5 MS4A1 SLC25A37 PDE4D TFRC TMEM38B FBXL5 GPR4 CYBRD1 SYNPO PTGIR KCNMA1 SLC12A4 SLC7A8 RMDN3 CCL3 PTPRC PTGER3 RAP1GDS1 WFS1 HTT GPR157 UBASH3B GNAI2 CALM2 PLCD1 PTH1R HEXB KCNA5 S1PR4 SLC8A1 PDE6A PSEN1 PDE6B CNNM2 ADRA1A JPH1 GSTO1 PTGER4 CCR7 ACKR3 PRKCE PTGER2 NPR1 GRIA1 ATP13A3 PRKACA SLC10A7 CLN3 PLCG2 ATP6V0D1 CALM1 PKD2 SYPL2 CCR4 EPB42 FPR2 ATP6V1A MCUR1 SLC24A1 SLC8A3 CCR1 SCARA5 NPTN GNA13 GPR18 CALB1 CCR6 FGF2 ABL2 FKBP1A SLC31A1 SCN7A SLC24A5 TPT1 CXCR4 CCR9 MT1M ISCU BOK CD19 ADORA2A EDN1 MCOLN2 P2RX1 MT2A LPAR6 ATF4 SMAD4	down	*
GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND	0.0001292	0.0023900	0.5188481	-0.2045383	-1.279582	936	SLC6A4 GPD1 CXCL3 KMO RAMP3 SIDT2 LPIN2 IL1A SASH1 EDNRB SCIMP PPARG CD55 CPEB2 IL1B LHCGR ADCY9 P2RY1 ADCY4 RAPGEF2 PTPRE PID1 INSIG1 KL PCSK9 FOLR1 FYN LPL LY86 RGS9 INPP5K CAV1 BAIAP2 CALCRL AQP9 MYD88 VAMP2 PLEKHA1 TBXA2R HMGCR PRKAR1A NR3C1 IL1RN GAS6 TRIB1 CASP9 RHOA PDE2A BRINP3 CD36 ANXA1 MIR146A SSTR1 ATP2B1 TRA2B RRAGC CARD16 FOXA2 RAP1A CLEC7A TNIP3 ANXA5 FZD4 LITAF KLF10 CAV2 ADIPOR1 EIF4E PPP3CA NR4A1 SIRPA ADRB2 TRAF6 NFE2L2 NDEL1 LAMTOR3 CRK SFRP1 WNT3A KANK2 ZEB1 ARHGEF2 SPI1 PDE4D TXN ATP6V1H ATP6V1B2 FOXC2 RHOB IL10 ROCK2 STAT5A ARRB1 RAB12 FOXO1 SRSF5 SORBS1 CASP1 PTAFR KLF4 ID3 KLF9 ROCK1 KLF11 SOCS2 ATP6V1D KLF7 LY96 PDE8A CCL3 SSH1 NFKB1 PDE3B P2RY2 SIK2 KCNMB1 CXCL2 IRAK2 VIM AXL ATP6V0D2 TLR4 PIK3C2A INHBA CPT1A PINK1 GNAQ CYP26B1 GNAI2 TBC1D4 IL24 BACE1 ACTR2 HCK SRF SLC25A33 PDK4 KANK1 MYO1C WNT9A SLC8A1 CD80 ADCY2 IL6 PSEN1 SOCS3 ESD APPL1 RAB8B RWDD1 JUN CPEB4 GABPA RAB31 USO1 ETS1 HRH1 ATP6V0B CARD8 PALM RAPGEF1 PTGER4 PIK3R1 IRF8 PRKCE GRB2 CREB1 PTGER2 MALT1 RAB8A UNC13B PRKACA CXCL5 GPR37L1 FOS ATP6V0D1 ADNP2 RHOQ KLF2 FOXO3 PKD2 MAPK8 TREX1 WNT11 DDX18 HNRNPD EPHA3 TGFB1 CD6 FPR2 GNAI1 ATP6V1A CD86 IRS2 PIM1 ATP6V0C PLSCR4 SLC8A3 GLRA1 SOD2 KLRC4-KLRK1 ACTN2 PLAA KAT2B PDE4B TSPO SOD3 ICAM1 SESN1 IL18 IL18RAP ABL2 TFPI HTR6 ARRB2 OSR1 TIAM1 EPHA4 RIPK2 NLRP3 PTCH1 ACTB HAVCR2 IPO5 OSER1 MBD5 DAPK1 FDX1 SIN3A NFKBIA GLRX2 RET RAPGEF3 EDN1 KLRK1 PTEN	down	**
MIR93_5P	0.0036060	0.0336481	0.4317077	-0.2120269	-1.278117	529	RAB11FIP1 EREG TMEM100 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	*
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B	0.0038358	0.0351647	0.4317077	-0.2174056	-1.276971	425	RBP4 SLC31A2 EREG SIDT2 OLR1 LRRFIP1 THBD SMIM12 HSD17B11 CD44 SOX17 CCRL2 MYADM MYD88 GPCPD1 C5AR1 CLEC10A FUCA1 SYNC GINM1 AVPI1 EDEM1 JPH2 ANXA1 SH2B3 DNAJC18 BMP1 LTBP4 HBEGF ASAH1 CHRNE CHMP1B EIF1 SERP2 BTG2 SERINC1 PICALM KLF6 RNASE1 CAV2 NR4A1 ADRB2 TMEM41B MAPK8IP1 BTG3 TFRC KRT4 MAP2K3 ROCK2 AMOTL1 AHNAK SORBS1 SAP30BP PLAUR SLC12A4 COQ10B FMO2 DRAM1 FBXL3 UBQLN1 TMBIM1 GPR85 TEF DUSP1 SMAD7 INHBA WFS1 ANXA3 CMTM6 PIAS1 HGSNAT NINJ1 AREG IL6 RGS18 UTRN CNNM2 CCDC3 INMT ETS1	down	*
MIR5590_3P	0.0059881	0.0488332	0.4070179	-0.2271806	-1.276083	296	EPAS1 ZC3H12C LDB2 NEDD4L MTMR10 S1PR1 MAL RGPD5 OTUD4 CIT ACER3 RHOA LACTB B3GNT5 TTL RAP1A ZDHHC2 ZNF503 KLF10 CAV2 SLC7A11 NFE2L2 TNS1 SOX7 EFCAB14 TBC1D9 BNIP2 PLAUR REST STK17B MED6 FBXL3 CLIC4 SPAG9 SSH1 CLK4 PIK3C2A ADIPOR2 TOPORS SNX3 CREBRF MED28 APPL1 PLEKHA3 MAGI2 PDCD6IP PPP6C CUL4A HELQ ACKR3 RC3H1 SNX1 ATP13A3 OGFRL1 RHOQ CDK17 PTP4A1 SRSF6 TMX3 NR2C1 PDS5B ABHD13 ZBTB11 MAP3K2 PPP3R1 HNRNPH3 PRDM8 SMAD2 RNF138 NBN LRP12 FBXO30 UBE2D1 ZNF471 NPAT PRKG1 RORA ZFPM2 RNH1 BMI1 TRIM36 MED17 ZNF326 STARD13 BHLHE41 FAM131B HIPK1 RB1CC1 DYNC1I2 CD109 ATP1B1 CCNT2 DNAJB4 IFIT5 CD69	down	*
GO_POSITIVE_REGULATION_OF_CELL_DIFFERENTIATION	0.0009339	0.0120428	0.4772708	-0.2011246	-1.275908	797	LIMS2 DAB1 SEMA6A TMEM100 ACVRL1 CD101 TAL1 PPARG GLIPR2 GATA2 SFRP4 IL1B DCSTAMP WNT4 RAPGEF2 PLA2G10 RAMP2 BMP2 TRPV2 CDH5 ENG FIG4 BDNF FYN LPL SHANK3 SOX17 MYADM NEDD4L BAIAP2 BMPR2 MEF2A CDC42 NEDD9 GAS6 TGFBR2 SCARF1 TRIB1 IL23A RHOA ZEB2 NUMB BRINP3 CD36 ANXA1 MIR146A CLCF1 ADA ARSB RAP1A PLXNA2 CLEC7A FZD4 KLF10 HLX GATA3 RBM4 PLXNA4 RB1 RGCC ISLR2 TRAF6 NFE2L2 NDEL1 GRN CRK SFRP1 WNT3A ZEB1 ARHGEF2 HNRNPU ITSN2 TCF7L2 ZNF365 CYB5D2 SETD3 ZMIZ1 EVI2B MSR1 PRDM16 SNAI1 SDCBP NPNT BNIP2 LIMS1 REST DAB2 ARNTL ADAMTS9 CEBPA SOCS2 CLDN5 SOCS5 MPL SPAG9 CCL3 NFKB1 PTPRC AXL ID2 SS18L2 CD53 INHBA TBX5 IL7R CYP26B1 PAFAH1B1 RUFY3 HES1 ADD1 AKIRIN1 MEDAG ACTR2 NCOA1 TGFB2 LMOD3 PIAS1 SRF SRGAP2C BTG1 NCKAP1L SNX3 RBPJ WNT9A CD80 CNTF IL6 PSEN1 SOCS3 MAGI2 NDNF JUN CCDC3 NOTCH1 RASSF10 ETS1 PDE5A TYROBP HSPA1B JUNB RAPGEF1 SKIL CD83 ZNF804A CREB1 MALT1 RPS6KA1 AP3B1 CD34 BLOC1S6 FOS RRN3 RUNX3 EHD2 FOXO3 CD74 MME EPHA3 TIMP2 SAV1 TGFB1 EHD1 TCF4 ZBTB1 TGFB1I1 APBB1 CD86 SOD2 MYOCD CCR1 NPTN GATA6 MACF1 RGS2 PLAA TSPO IST1 SMAD2 JUND UNC13D FGF2 IL18 ABL2 ARPC2 ARRB2 CEBPD TIAM1 CXCR4 EPHA4 RIPK2 NLRP3 PTCH1 STK4 SIN3A RET KIT EDN1 ETV2 PTEN LTBP3 TNFSF9 MMD C21orf91 FGFR1	down	*
SWEET_LUNG_CANCER_KRAS_UP	0.0030103	0.0292390	0.4317077	-0.2196027	-1.275496	393	RBP4 SLPI PPARG OSBPL1A HHEX SNX10 CLDND1 LRRFIP1 CD44 CITED2 CYB5R3 VAMP2 ARL8B MARCO BCL2A1 CD9 FUCA1 PSMD5 AVPI1 EDEM1 PLA2G7 SPG21 PCYOX1 C16orf89 ENTPD1 IFI30 LITAF HDC LCP1 SIRPA RGCC BTG3 APOC1 HMGN1 MSR1 MPEG1 BST1 PIP5K1B OSTF1 VASP THBS1 CEBPA SOCS2 PLBD1 FAM49B CTSD LAPTM5 CDKN1A COTL1 ITGAX CXCL2 AXL ID2 ADIPOR2 PPP2R5C CLIP4 HLA-DQA1 RABGGTB BTG1 RNF149 AREG CTSS TULP2 PSEN1 CYB5R1 SFTPB CTSZ TYROBP HSPA1B ATP11A AK1 CDK2AP2 ATP6V0D1 SRSF6 CD74 CHIA AZIN1 TGIF1 FPR2 ATP6V0C COL15A1 LGALS3 TOB1 ACADL ELF5 IL18 SLC34A2 ZNF143 SLC31A1 ELOVL1 CES3 PARM1 HSPA8 SOAT1 C17orf49 CTSC ETV2 CHCHD7 TNFSF9 NABP1 IQGAP1 RAP1GAP CSF2 CYBA ATP6V0A1 CSF2RB IGKV2-30 SERPINE1 C1QB CTSH DUSP6 TMEM30A C5 MAPK1 GAS5 TGOLN2 SLC38A2 NUP88	down	*
MIR23C	0.0019921	0.0213746	0.4317077	-0.2155011	-1.274784	491	WEE1 EPAS1 TRHDE SOWAHC ZC3H12C CPEB2 PTPRB TTC7B RCOR1 ZBTB34 MED4 KIAA1109 NEDD4L CALCRL ZCCHC2 ELF2 INPP5A ARL8B MEF2A RXFP1 WBP4 LAMP1 AGPAT4 ZBTB2 TGFBR2 TRIB1 C12orf76 SEMA6D RAP1A MTF1 SWT1 ECHDC1 SERINC1 NLK GLS CAMTA1 ZEB1 MYCT1 TMEM38B SCP2 CLEC1A BNIP2 PPM1K TJP1 TMED5 GRK5 CDS2 PNRC1 ZBTB43 N4BP1 VEPH1 NUS1 CNOT6L VCPKMT NCOA1 C2orf69 LIN54 TMOD1 CDC40 PKNOX1 NEK7 MAML2 RAB8B PRPH2 SEC14L1 DDX47 MITF PNMA2 CARD8 MAP4K4 TBC1D12 PTGER4 DHX15 SDHD PRKCE GTDC1 DENND4A CGGBP1 CELF2 GAS2L3 CDK17 FOSB PKIA NAA16 NAP1L5 STRN NDUFA5 TGIF1 TEX30 CBFA2T3 ATXN1 MEIS1 WBP2 STX12 MICU3 ZNF267 PDE4B CCNH BNIP3L FGF2 INTS6 RPP30 SFT2D1 ORMDL1 TMOD2 UBE2D1 IPO5 FBXO25 MEX3C BRWD1 G3BP2 SSH2 KPNA4 STK4 CUL3 JMJD1C RNF38 PAK2 PTEN FAM126B CAMSAP2 RORA MT2A TLK1 SPOPL CNN2 LYZ ZBTB44 SNRPG MAP4 REEP1	down	*
GO_CELLULAR_COMPONENT_MORPHOGENESIS	0.0004870	0.0071928	0.4984931	-0.2022722	-1.274748	925	TNR LIMS2 WEE1 DAB1 SEMA6B SEMA3G CLEC1B SEMA6A SIDT2 WTIP COL25A1 TEK PHACTR1 DLC1 TAL1 PECAM1 FGD5 ROBO4 P2RY1 RDX DPYSL2 RAPGEF2 PLA2G10 LIPA PID1 TRPV2 CDH5 FIG4 BDNF FYN SHANK3 EGR2 CD44 TMOD3 SOX17 RADIL CORO1C MYADM NEDD4L BAIAP2 CDH13 BMPR2 CDC42EP2 PRKAR1A MEF2A CDC42 NEDD9 CD9 DSCAML1 EPB41L3 SCARA3 FGR HEG1 CASP9 RHOA ZEB2 NUMB SEMA6D ANXA1 MYOZ1 PTPRM SEMA3B TTL HECW2 PLXNA2 CSRP1 RANBP9 PARVG PICALM FZD4 GATA3 PPP3CA ZMYM6 PLXNA4 RB1 ISLR2 NDEL1 CRK SPTBN1 WNT3A ARHGEF2 ITSN2 TCAP ZNF365 GPM6A NODAL ATP10A RHOB LRP4 ADARB1 AGO4 PTPRO LIMS1 ZSWIM6 TRIM46 NES PSPN ROCK1 PARVB VASP KLF7 MPL CLIC4 SEC24B FMNL3 LAMC3 CCL3 SSH1 C9orf72 ARHGEF26 AXL KIRREL3 ID2 ARC SS18L2 WASF3 ZMPSTE24 MATN2 PEAK1 UNC5A IL7R MYH11 PAFAH1B1 RUFY3 HES1 ADD1 ACTR2 SIAH1 TGFB2 LMOD3 HEXB HCK SRF NCKAP1L KANK1 FMNL2 VAMP3 FRY TMOD1 WASF2 SGK1 PSEN1 CABP4 PIKFYVE LAMB2 NOTCH1 RHOBTB2 LIMD1 RAC2 MAP4K4 CNTN4 RHOG APBB2 RHOJ PALM FERMT2 SNX2 SKIL IFRD1 PIK3R1 GRB2 FRYL CREB1 RAB8A RTN4R SNX1 CAP1 TRAK2 PREX2 PALMD PANK2 AGFG1 RHOQ UBB KLF2 EPHA3 EPB42 ZRANB1 HECW1 MTMR2 YTHDF2 TGFB1I1 APBB1 IRS2 CNTNAP1 SLIRP C8orf37 DOK2 NPTN CLASP2 GNA13 ACTN2 MACF1 PLAA ADAM10 IST1 PITPNA UNC13D ICAM1 PDLIM5 ARPC2 WDR1 EPB41L5 LMOD1 SEMA4A RTN4 CDC42EP3 TIAM1 CXCR4 HSP90AA1 DACT2 TMOD2 EPHA4 ARHGAP18 PTCH1 ACTB MEGF9 BRWD1 EPHA2 SSH2 RND1 ULK2 PARVA NEK3 STK4 CUL3 SIN3A RET ADORA2A KIT EDN1 DOCK10 PTEN B3GNT2	down	**
MIR4659A_3P_MIR4659B_3P	0.0015836	0.0179626	0.4550599	-0.2103772	-1.271969	545	AJAP1 SC5D FOXF1 ABHD5 PHACTR1 SGK3 ADTRP CD55 ZC3H12C CPEB2 P2RY1 KCTD9 MED4 DDX6 CALCRL FLVCR2 AKAP7 NTM PAFAH1B2 MOB1B TLCD2 PPM1N ZEB2 EDEM1 NFIX HBEGF HECW2 LIFR ENTPD1 MTF1 ANXA5 NLK CSGALNACT2 RNF182 MED19 ADIPOR1 ZBTB8A DACH1 GATA3 PLXNA4 TRAF6 TNS1 SPTBN1 HPSE2 RAB14 CD58 FBXL5 KDSR CYBRD1 MTMR6 LIN7C ITM2B ZFAND5 STK17B THBS1 KLF7 NPR3 GPR85 CXXC4 PTGER3 ZMPSTE24 DSE RUFY3 AFF1 CRIM1 MEDAG RASGEF1B PDK4 SLC8A1 ID4 VPS37A CREM YBX1 PIKFYVE HCFC2 UTRN LRCH1 PNMA2 GABPA ZFP91 DESI2 JPH1 C11orf58 NXPE3 WTAP SKIL IFRD1 GLIPR1 TTC14 SP3 PIK3R1 CD83 FSD2 UNC13B WDR7 PALMD CACYBP ING3 ITGA9 PDS5B PCDH17 MYOCD ANKRD12 SBSPON RIMKLB CALB1 MBNL1 SYT11 HELZ MOB3B TNFAIP8 ALDH1B1 ARRB2 DCTN4 TIAM1 VPS4B DACT2 TAB2 RIPK2 DIXDC1 RBM18 ZDHHC21 CREBBP SSH2 RBMS3 KATNA1 ARPC5 FNIP2 CHCHD7 TMEM87A MTUS1 MMD C21orf91 THEMIS2 NRG1 NABP1 SFPQ CCDC144A	down	*
MIR302E	0.0042408	0.0378744	0.4070179	-0.2190122	-1.271113	415	RAB11FIP1 TMEM100 EDNRB FGD5 SOWAHC RDX TMEM170B RASAL2 GPCPD1 TBC1D2 TET2 TGFBR2 SYNC TEX2 TXNIP ASAP1 LATS2 MTF1 MASP1 HIPK3 SLAIN2 TMEM123 LHX6 PDE4D MCL1 CYB5D2 GPM6A TIPARP CYBRD1 TAPT1 ROCK2 PRDM16 PTPN21 ZCCHC24 SETD9 REST PDE8A NPAS3 ST7L C9orf72 CYP20A1 SHC4 FRMD4A UBE2B MBD2 CLIP4 MPC1 CYP26B1 SMNDC1 USP16 CRIM1 TANC1 KREMEN1 C2orf69 BTG1 CREBRF PDIK1L DNAJC27 DDHD1 PIKFYVE PPP6C C2CD2 ATP6V0B OSTM1 ARHGEF10 RABGAP1 JAK1 KBTBD8 FSD1L ZNRF3 NOL7 RASSF2 SNRK CELF2 YTHDF3 PKD2 TSHZ3 SPOP ZRANB1 TESK2 RSBN1L SKIDA1 ZBTB11 MAP3K2 RELL1 ATXN1 TAGAP SCARA5 KAT2B IFNLR1 PRDM8 INO80D SLC43A2 BNIP3L CHURC1 ITPRIPL2 RTN1 TIAM1 CXCR4 MFAP5 ZBTB25 NHLRC3 CUL3 PAK2 MTUS1 LYST RORA SLC22A3 ANO6 GRPEL1 MIER3 TRIM36 MED17 IRF2 ZFYVE26 SLC16A10 PLAG1 ARHGEF17 CFL2 ZNF800 NR4A2	down	*
MIR124_3P	0.0016012	0.0181059	0.4550599	-0.2056587	-1.270353	661	RAB11FIP1 SLC31A2 SEMA6A ABHD5 EDNRB OSBPL11 ADCY9 MBOAT2 CLDND1 RCOR1 EGR2 PLEKHF2 RGS9 CAV1 MYADM THAP2 QKI SLC25A30 MTMR10 CTDSP1 MEF2A TSHZ1 CBL GGA2 CASP9 EDEM1 SEMA6D SH2B3 NFIX TTL CYB5A ZNF503 ANXA5 FZD4 LITAF HIPK3 KLF6 LCP1 STOM NR4A1 MED26 SLC25A37 AKT3 PTPN12 EFCAB14 AMOTL1 DUSP3 LRRC57 DENND6A LIMS1 ZCCHC24 PLEKHM3 ROCK1 USP2 TNFSF15 CEBPA MYRIP KIF26A ABCC4 SNIP1 TMBIM1 SSH1 ATL3 MGAT4A RBMS1 VIM TADA2B C9orf72 JAM2 PIK3C2A ELK3 ZMPSTE24 CPT1A CUL5 ILDR2 ZNF706 MYH11 FKBP15 KPNA3 TLL1 LMBRD1 RSRC2 C2orf69 SERTAD2 KANK1 MYLIP MYO1C CREBRF VAMP3 GZF1 WASF2 SGK1 PHACTR2 UBQLN3 ARL5B MITF VAT1 ETS1 DNASE2 RHOG APBB2 RAPGEF1 WTAP FERMT2 ENPP4 EEA1 PI4K2B GRB2 MAPK4 RPS6KA1 SLC10A7 FAM177A1 THSD7B GFPT2 PPM1F ACSL1 BLOC1S6 CD151 POGLUT1 ADNP2 RHOQ PNPLA2 CD164 HIVEP2 ECI2 SRSF6 XYLT1 NAP1L5 CPA3 EPHA3 TFEB PEA15 ZBTB11 GNAI1 MCUR1 MAP3K2 PIM1 ORC2 PHF19 GATA6 PDE4B RXRA ANKLE2 PDLIM5 SLC31A1 PUS10 DCTN4 TMEM184B RBMS3 ULK2 TMEM109 KLLN KATNA1 LIMCH1 BCAT1 RASSF8 SNAP29 PRKG1 ANXA11 NR3C2 NAA15 IQGAP1 WDFY3 SPOPL ENY2 SLC44A5 EVI5 PAPSS2 GPALPP1 FNBP1 REEP1 SUGT1 EGR1 CHP1 CDON CHIC2 SLC25A38 SPPL2A SVIL KCNJ6 ENDOD1 HIPK1 USP30 CLOCK MYH10 ITGB1	down	*
GO_INNATE_IMMUNE_RESPONSE	0.0009784	0.0125030	0.4550599	-0.2043212	-1.268303	692	POLR3H SIRPB1 NLRC4 SLPI EREG CD300LF FCN1 CXCL16 SCIMP SIGLEC16 PPARG CD55 FCN3 MNDA FYN CD44 LY86 CCL3L1 SAMHD1 CLEC12B CAV1 MYD88 CDC42EP2 CD300E CLEC10A RBM14 CDC42 MARCO NCF2 OTUD4 PSMD5 LAMP1 SLC11A1 RFTN1 IL23A FGR CD36 ANXA1 MIR146A CLEC7A MASP1 TNIP3 IFI30 RNF125 PTX3 IFNK SERPINB9 GATA3 SIRPA TRAF6 GRN CRK CRTAM ARHGEF2 UBE2D3 CD58 ADARB1 CFD CCL22 RAB12 BIRC2 MEFV MPEG1 CASP1 SLC46A2 PTAFR LY96 UBQLN1 CCL3 NFKB1 CADM1 IRAK2 VIM AQP4 AXL CCL4 TLR4 ACTR3 SFTPD XCL2 CAPZA2 FCER1G KLRD1 HLA-DQA1 C4BPB CD300LB ACTR2 PIAS1 HCK MYO1C VAMP3 MUC3A CD160 CTSS SOCS3 APPL1 OASL PPP6C SEC14L1 C1QA PSMA1 TYROBP TREM1 HSPA1B IFNGR1 JAK1 IPO7 IRF8 PRKCE MALT1 SIGLEC15 PRKACA ZNF683 PLCG2 UBB PELI1 YTHDF3 PSMD12 ICAM2 TREX1 KLRC2 CR1 PIK3AP1 SMPDL3B IRF5 STXBP3 SIGLEC14 AKIRIN2 AP1G1 CD1D ZBTB1 CD6 FPR2 YTHDF2 PDE12 NLRP6 IFNAR1 PIK3C3 CNOT7 LGALS3 KLRC4-KLRK1 IGHV3-23 KYNU SERINC3 MR1 IFNLR1 CCL20 UNC13D ICAM1 IL18 IL18RAP ARRB2 RTN4 CALCOCO2 TAB2 RIPK2 NLRP3 UBE2D1 SP100 HAVCR2 PSME4 G3BP2 CREBBP ICAM3 DAPK1 TLR10 SIN3A NFKBIA EDN1 PAK2 KLRK1 LYST MCOLN2 AIM2 ITCH PSMD6 MT2A PSMD9 SFPQ PUM1 IRF2 UBE2V1 CYBA EPG5 EGR1 C1QB TREML1 CX3CR1 CLEC4E C5 TREM2 NCF1 ZYX S100A8 PIK3CG SIGLEC10 MUL1 IFIT5 HLA-DRB1 WNT5A SSC5D MAP4K2 UBE2N BCL10 TRIM13 CAPZA1 MATR3 ANKHD1 HMGB1 DDX21 NMI EP300 IRF1	down	*
GO_REGULATION_OF_HEMOPOIESIS	0.0026130	0.0262135	0.4317077	-0.2184664	-1.265743	384	CD101 ACE TAL1 KLF13 GATA2 DCSTAMP LMO2 GAS6 PSMD5 TGFBR2 TRIB1 LILRB3 IL23A RHOA ANXA1 FBXO7 ADA KLF10 FOXP1 HLX ASH2L GATA3 RB1 TRAF6 NFE2L2 SFRP1 ZEB1 SPI1 ZMIZ1 EVI2B AGO4 NRARP AGO3 SLC46A2 THBS1 SOCS5 MPL CCL3 PTPRC AXL ID2 TLR4 SMAD7 INHBA IL7R UBASH3B CYP26B1 HES1 MIR17HG NCKAP1L IL17D CD80 JUN PSMA1 MITF NOTCH1 GABPA CUL4A ETS1 TYROBP HSPA1B ATXN1L PIK3R1 CD83 CREB1 OSM MALT1 SIGLEC15 RC3H1 AP3B1 FSTL3 TBX21 RASSF2 ZNF683 FOS PSMD12 RUNX3 FOXO3 CD74 CR1 TGFB1 ZBTB1 YTHDF2 CD86 PIM1 LGALS3 MEIS1 CCR1 N4BP2L2 KAT2B IL18 RIPK2 NLRP3 TOB2 PSME4 CREBBP SIN3A NFKBIA TNFSF9 GPR171 ITCH PSMD6 PSMD9 PURB	down	*
MIR20B_5P	0.0054835	0.0457371	0.4070179	-0.2087827	-1.263184	530	RAB11FIP1 EREG TMEM100 FGD5 ZC3H12C DPYSL2 EGR2 NEDD4L CRY2 TMEM138 BMPR2 S1PR1 AGTPBP1 OTUD4 TGFBR2 HPS5 HEG1 TXNIP ZBTB4 PPP1R15B MTF1 MAP3K8 PBX3 REV3L ZBTB21 CAMTA1 PAG1 PEX5L ZBTB8A SLAIN2 FOXJ3 LHX6 NDEL1 ANKRD29 BTG3 MCL1 FBXL5 ADARB1 EFCAB14 CYBRD1 ROCK2 TBC1D9 PTPN21 AHNAK BNIP2 KIAA0513 REST KLF9 KLF11 DAB2 STK17B FBXL3 SSH1 ATL3 PDE3B NKIRAS1 UXS1 ELK3 WFS1 CLIP4 NCKAP5 TANC1 CNOT6L CNRIP1 ST6GALNAC6 C2orf69 TOPORS PRCP SERTAD2 MYLIP FLT1 FAM189A1 DNAJC27 DDHD1 PLEKHA3 RAB8B PPP6C C2CD2 LRCH1 SH3BP5 ZFP91 OSTM1 ARHGEF10 DUSP8 ATXN1L PIK3R1 DDX5 CREB1 OSM MAPK4 ENTPD4 FSD1L ZNF597 NAA30 PXK AGFG1 RUNX3 PKD2 BTBD7 UBXN2A TMX3 ATG2B NR2C1 ZFYVE9 CDC37L1 CNOT7 MAP3K2 HBP1 PPP3R1 TAGAP KAT2B PITPNA RBL2 PDLIM5 ABL2 CEP170 ITPRIPL2 OSR1 TIAM1 EPHA4 HSPA8 BRWD1 SSH2 NPAT NHLRC3 LYST DNAJB9 FAM126B RORA FAM13C LDLR DOCK4 ZFPM2 NABP1 WDFY3 EIF4A2 RNH1 SPOPL PURB SMAD4 ANO6 TRIM36 ZFYVE26 ARHGEF18 ABI1 PLAG1 FJX1 CFL2 BHLHE41 AKTIP ZNF800 MAPK1 CLOCK CMPK1 RB1CC1	down	*
GO_DEFENSE_RESPONSE_TO_OTHER_ORGANISM	0.0006432	0.0090410	0.4772708	-0.1999231	-1.263171	815	POLR3H SIRPB1 SIGLEC11 NLRC4 SLPI EREG ACP5 CD300LF FCN1 CXCL16 SCIMP SIGLEC16 PPARG CD55 FCN3 SPN PGC IL1B MNDA FYN CD44 LY86 CCL3L1 SAMHD1 CLEC12B CAV1 MYD88 CDC42EP2 CD300E C5AR1 CLEC10A RBM14 CDC42 MARCO NCF2 OTUD4 PSMD5 LAMP1 SLC11A1 RFTN1 IL23A FGR CD36 ANXA1 MIR146A DNAJC3 ADAM17 CLEC7A MASP1 TNIP3 IFI30 RNF125 FOXP1 PTX3 IFNK SERPINB9 GATA3 SIRPA TRAF6 GRN CRK CRTAM ARHGEF2 UBE2D3 RAB14 CD58 ADARB1 IL10 CFD CCL22 RAB12 BIRC2 MEFV MPEG1 CASP1 SLC46A2 PTAFR LY96 UBQLN1 ATG7 CCL3 NFKB1 COTL1 CADM1 PTPRC IRAK2 VIM AQP4 SELP AXL CCL4 TLR4 ACTR3 SFTPD XCL2 CAPZA2 PRF1 FCER1G ZMPSTE24 KLRD1 HLA-DQA1 C4BPB ANXA3 CD300LB ACTR2 PIAS1 HCK RBPJ MYO1C VAMP3 IL6 MUC3A CD160 CTSS SOCS3 APPL1 OASL PPP6C SEC14L1 C1QA PSMA1 DDX17 TYROBP TREM1 HSPA1B IFNGR1 JAK1 IPO7 IRF8 PRKCE MALT1 SIGLEC15 UNC13B PRKACA ZNF683 IGKV3-20 PLCG2 UBB PELI1 YTHDF3 PSMD12 ICAM2 TREX1 KLRC2 ZNF175 CR1 PIK3AP1 SMPDL3B IRF5 STXBP3 SIGLEC14 AKIRIN2 AP1G1 CD1D ZBTB1 CD6 FPR2 YTHDF2 PDE12 NLRP6 IFNAR1 PIK3C3 CNOT7 LGALS3 KLRC4-KLRK1 EXOC1 IGHV3-23 KYNU SERINC3 MR1 IFNLR1 CCL20 SYT11 UNC13D ICAM1 BNIP3L IL18 IL18RAP VGF ARRB2 RTN4 CALCOCO2 TAB2 RIPK2 NLRP3 UBE2D1 SP100 HAVCR2 PSME4 EPHA2 G3BP2 CREBBP ICAM3 DAPK1 TLR10 SIN3A NFKBIA EDN1 PAK2 KLRK1 LYST MCOLN2 AIM2 ITCH PSMD6 MT2A PSMD9 SFPQ PUM1	down	**
LHX2_TARGET_GENES	0.0023263	0.0240354	0.4317077	0.2463729	1.261721	1124	ATP10B PDE11A PRR15 PPM1H SYT8 CEACAM1 PRLR STYK1 EGLN3 CDH17 LAD1 GMDS RPGRIP1L BUB1B IGF2BP3 DROSHA CIB2 TTF2 CHCHD6 NUDCD3 NDC80 GUCY2C PRIM2 TBRG4 ZNF138 MRPL46 TUBB2B C6orf141 PRR15L KIF14 STK31 ANKRD24 COL7A1 CDCA8 ACAD9 ALDH18A1 ECT2 CDC6 ACOT8 NNT GOLGB1 SPATS2 STRIP2 BCL2L14 TYMS XPNPEP1 PMS2 NWD1 EFNA5 PLS1 ZFYVE19 ZNF3 CAND1 VILL NCAPD2 ZNF608 UQCC1 NME1 AARS2 WDR62 RSPH1 TMEM41A SDR16C5 EXO1 ZNF391 SYTL2 PCCB KIF3B RPL32P3 AURKA NUP155 THBS4 MYO10 C1orf226 LARS2 TPR SMARCAL1 E2F2 ZNF860 TTC22 CDCA5 CDNF SETDB1 ERAL1 AIMP2 EMG1 ZNF785 TARS2 WDR60 PSMG4 EGFR OAZ3 ZNF443 LINC00265 ZNHIT1 C7orf50 PEX26 ACTL6A PIH1D1 MRPS11 DNAH11 FDXR SAMD10 GRHL2 PHB FADS2 ERCC2 PIGO SRRM5 UQCR11 CNPY2 POLN TNIK CDKN2C CAPN8 FRMD5 FAHD2A KRT18 DMKN PABPN1 HDGF CDK12 EPHA1 SSBP1 PICK1 PACS1 TNK2 AAGAB ADAP1 NCAPG PSMB5 PRPF6 SDCBP2 ENPP3 FEN1 CDH3 TTC6 TMEM79 PSMG3 LINC00649 METTL3 THAP8 USP42 MYO5B MTBP PSMC4 TSPAN1 CENPP FOCAD DNAJC7 UNC45A TPD52L2 RNF44 HYKK ILF2 DNAJC17 VIPAS39 C19orf44 SATB2 DCAKD SMG5 NDUFA11 VPS41 DNAH7 JOSD2 LRFN3 MAN1B1 ARHGAP32 CCDC151 GPRC5C SLC37A4 RAD51D ACBD4 PPOX KIF21A MSI2 CSNK1G1 CCDC146 FZR1 LIN37 ZSWIM3 ZSWIM1 GFM2 C15orf41 CKMT2-AS1 IQCH CDK13 LTBR FAM200A FLG-AS1 CCDC159 ENC1 NIF3L1 CENPK FAM71E1 EFCAB7 LIMA1 L3MBTL2 WDR34 TUBG2 ZCCHC17 FAF1 HMGB3P22 NOL6 ABCC3 KRT8 MRPL24 KDM4B MRPS33 WDR83 RPL7L1 CENPT ZSWIM8 NSUN6 KPTN SPINK5 C1orf56 SLC35A3 SCYL3 C1orf109 TBC1D16 GINS3 FBXO36 HOXA-AS3 SNX11 NEURL4 MRPL51 CYP4F12 MIB2 HAUS4 SLC1A5 PALM3 NEDD8 VPS53 SF3A2 ATAD2 GOSR2 EIF3K DUS2 SPSB3 KLHL7 SH3D21 NME1-NME2 AMN1 PRPF18 RPS26 RRNAD1 TM7SF3 DBNL BBX MANBAL MRPS25 DTNB CTU1 STAT6 ZNF436 CCDC9 PRPF31 HAS1 NUBP2 OSBPL10 BMS1 CAPN10 TRIP4 BRMS1 PFKM ST20 ZNF217 SAMD4B MRPL9 ZSCAN22 MICU1 SNRNP200 TMEM101 ERBB2 TBC1D32 CPOX ZNF131 SIRT6 BCAS3 BCL6 GMPR2 XPC TCF3 DNAJC14 ADAM15 FZD3 POP4 GLYCTK ZMAT2 ALG1 GGCX NMT1 ZNF526 IDUA SNRPC TTC30B TBL3 NCAPD3 CDKAL1 SFXN5 TMEM38A ZER1 STK11IP IMMP2L CLASP1 ILVBL FAM222B SCAF1 ZNF337 FTSJ3 TRAPPC6A KCNK6 ANKRD11 ANKRD13D ALKBH2 CLNS1A CSTF1 COPE FAM47E INO80B NDUFAF6 HEXIM2 VPS26B DCAF16 PDXP MRTO4 CFI MBTD1 HGD DHDDS RFFL PPP1R13L CXorf40A ITGB5 METTL4 PM20D2 MED15	up	*
GO_POSITIVE_REGULATION_OF_IMMUNE_RESPONSE	0.0033346	0.0316809	0.4317077	-0.2038987	-1.261640	668	NLRC4 EREG CD300LF FCN1 GCSAML SCIMP CD55 FCN3 GATA2 PGC IL1B MNDA LPXN BTNL9 FYN CAV1 BAIAP2 PRAM1 MYD88 ELF2 PLEKHA1 C5AR1 CLEC10A RBM14 ELMO1 CDC42 MARCO CD1C OTUD4 PSMD5 LAMP1 CD22 SLC11A1 RFTN1 IL23A FGR CD36 ANXA1 MIR146A SPG21 CLCF1 IGKV2-28 ADA RAP1A CLEC7A MASP1 TNIP3 RNF125 FOXP1 HLX PAG1 MS4A1 IFNK GATA3 RGCC IL18R1 TRAF6 CRK CRTAM PDE4D UBE2D3 TFRC CFD DUSP3 BIRC2 SLC46A2 PTAFR SOCS5 LY96 FAM49B UBQLN1 NFKB1 CADM1 PTPRC IRAK2 TLR4 ACTR3 SFTPD FCER1G HLA-DQA1 C4BPB ACTR2 TGFB2 HCK NCKAP1L IGLV2-11 MYO1C CD80 ELF1 IL6 WASF2 MUC3A CD160 CTSS PSEN1 APPL1 SEC14L1 C1QA PSMA1 HSPA1B RAPGEF1 CCR7 STX7 PIK3R1 PRKCE GRB2 MALT1 RC3H1 PRKACA TBX21 IGKV3-20 PLCG2 UBB PELI1 TNFSF13 PSMD12 ICAM2 TREX1 CD74 CR1 PIK3AP1 SMPDL3B TGFB1 VAV3 AP1G1 CD1D ZBTB1 TEC FPR2 NLRP6 PIK3C3 CD86 CD81 LGALS3 KLRC4-KLRK1 IGHV3-23 BAG6 FCGRT PDE4B IGKV1D-39 TRAC IL18 IL18RAP LAT ARPC2 ARRB2 RTN4 HSP90AA1 TAB2 RIPK2 NLRP3 UBE2D1 ACTB HAVCR2 PSME4 CREBBP ICAM3 CD19 TLR10 SIN3A NFKBIA CD1E CD3G ARPC5 PAK2 KLRK1 AIM2 THEMIS2 ITCH PSMD6 PSMD9 SFPQ PUM1	down	*
GO_ACTIN_FILAMENT_BASED_PROCESS	0.0013403	0.0159812	0.4550599	-0.2057253	-1.260459	632	SWAP70 TEK PDLIM2 PHACTR1 DLC1 FGD5 ATXN3 WNT4 EMP2 RDX GPR65 ARHGEF15 SHANK3 TMOD3 CGNL1 CCDC88A INPP5K BAG4 KANK3 CAV1 CORO1C MYADM NEDD4L BAIAP2 CDC42EP2 ESAM S1PR1 FGF10 PRKAR1A MEF2A ELMO1 CDC42 NEDD9 EPB41L3 CIT SCN5A RHOA ANXA1 MYOZ1 CORO6 CSRP1 PARVG SPIRE1 LCP1 DES JAM3 RGCC CRK SFRP1 SPTBN1 ARHGEF2 TCAP PDE4D SETD3 PDGFA CNN1 SORBS3 EPB41L2 RHOB ROCK2 AMOTL1 ARRB1 SYNPO TNNC1 SDCBP SORBS1 BST1 DAAM2 ROCK1 PARVB VASP MYO1B FMNL3 SSH1 COTL1 VIM C9orf72 ACTR3 CAPZA2 WASF3 PLEK DSTN RAP1GDS1 MYH11 PAFAH1B1 RUFY3 ADD1 ARHGDIB ACTR2 LMOD3 HCK MTPN SRF NCKAP1L ARHGAP17 KCNA5 KANK1 MYO1C FAM107A FMNL2 SCN4B TMOD1 WASF2 SYNPO2 PDCD6IP RHOBTB2 RAC2 TYROBP ARHGEF10 RHOG RHOJ PTGER4 CCR7 IQSEC3 PIK3R1 GMFG PRKCE GRB2 SIGLEC15 CAP1 THSD7B PPM1F GAS2L3 ESPNL SNX9 RHOQ EHD2 WNT11 WHAMMP3 EPHA3 TESK2 PDLIM1 KCNN2 CLASP2 ACTN2 PDE4B PRICKLE4 ICAM1 PDLIM5 ABL2 ARPC2 WDR1 EPB41L5 LMOD1 XIRP1 IQSEC1 CDC42EP3 TMOD2 ARHGAP18 DIXDC1 ACTB GPD1L SSH2 RND1 SDAD1 PARVA LIMCH1 CUL3 RAPGEF3 KIT EDN1 ARPC5 EPB41L4A	down	*
GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS	0.0035328	0.0331333	0.4317077	-0.2129135	-1.259070	476	SMAD6 SEMA6A SWAP70 PHACTR1 RASIP1 HHEX IL1B FABP4 FBP1 PID1 ENG INPP5K BAG4 CAV1 CORO1C MYADM CRY2 CTDSP1 HMGCR PRKAR1A CBL TRIB1 HEG1 RHOA MIR146A CNST MYOZ1 SH2B3 DNAJC3 FBXO7 FOXA2 LATS2 PPP1R15B HSPB1 RANBP9 HIPK3 PAQR3 SIRPA FAM122A RB1 SFRP1 SPRY2 HNRNPU MAPK8IP1 PDE4D APOC1 PDGFA ADARB1 ROCK2 ARRB1 ITPRIP DUSP3 FOXO1 KLF4 ROCK1 CEBPA SOCS5 CDKN1A PTPRC ATF3 C9orf72 TLR4 MIR24-2 UBE2B PER1 DUSP1 SMAD7 PLEK INHBA PINK1 PPP2R5A GNAQ UBASH3B PAFAH1B1 FKBP15 GNAI2 CALM2 TGFB2 NCKAP1L PKIG PPP2CA RNF149 PSEN1 PHACTR2 SOCS3 JUN SH3BP5 DNAJA1 DUSP8 PPP1R15A RAPGEF1 IPO7 GMFG RASSF2 GPRC5A ZCCHC9 PPM1F SPRY4 CALM1 PKIA CHORDC1 TGFB1 PARD6A SMCR8 PDE12 NLRP6 DUSP5 CBFA2T3 IRS2 TERF2IP LGALS3 MYOCD RGS2 KAT2B DBNDD2 ARPP19 ANKLE2 LDLRAD4	down	*
GO_REGULATION_OF_GROWTH	0.0049678	0.0425430	0.4070179	-0.2088088	-1.258718	529	SLC6A4 TNR RBP4 SEMA6B SEMA3G SEMA6A ACVRL1 IL17RB CXCL16 SGK3 PPARG WFDC1 FBP1 DCSTAMP DPYSL2 TRPV2 BDNF SOX17 KIAA1109 NEDD4L BMPR2 CDC42 TGFBR3 NEDD9 GAS6 USP47 EPB41L3 TGFBR2 RFTN1 RHOA SEMA6D TBX2 WWC2 MYOZ1 LTBP4 SEMA3B HBEGF CACNA2D2 TTL ADAM17 LATS2 HLX ADIPOR1 ADRB1 FAM122A PLXNA4 RB1 ADRB2 ISLR2 NDEL1 SFRP1 WNT3A BNIPL ITSN2 FOXC2 EXOSC9 STAT5A PPT1 SDCBP TRIM46 YBX3 SOCS2 SOCS5 KIF26A CDKN1A ST7L IGFBP2 TAF9 ZMPSTE24 INHBA ADIPOR2 TBX5 WFS1 PAFAH1B1 RUFY3 MIR17HG CDKN2AIP TGFB2 MTPN SRF BTG1 SLC25A33 SERTAD2 RBPJ FAM107A PPP2CA PRDM11 SGK1 EBAG9 SOCS3 NOTCH1 HSPA1B EPC1 APBB2 IFRD1 CREB1 OSM NPR1 RTN4R RPS6KA1 EGLN2 PPM1F MORF4L1 ADNP2 EPPK1 WNT11 ING3 CHPT1 SAV1 TGFB1 OSGIN1 APBB1 PIM1 MEIS1 MYOCD GATA6 MACF1 RGS2 PLAA ADAM10 IST1 FGF2 INO80 SEMA4A RTN4 CXCR4 LRP12 PTCH1 ACACB MT1M ULK2 MBD5 ING2 STK4 SIN3A EDN1 PAK2 PTEN FGFR1 MIR548C ITCH ZFPM2 MT2A CREG1 SMAD4 SPHK1 EIF4G2 CYBA KAT5 HTRA2 GREM1 GHR CDKN1B DUSP6 MAPK1 ING1 DCUN1D3 OSGIN2 S100A8 CPNE9 NOG	down	*
MIR548E_5P	0.0014805	0.0170721	0.4550599	-0.2061572	-1.254730	619	CXCL16 CPEB2 MNDA ATXN3 PRKG2 ADCY9 RDX KCTD9 PID1 BDNF TXNL1 BAG4 KIAA1109 CALCRL QKI DYRK1A PRKAR1A NR3C1 TET2 MOB1B NFATC3 ARHGAP29 CD36 ATP2B1 LACTB STARD9 RRAGC ASAP1 SLC36A4 LIFR LATS2 ZDHHC2 SERINC1 FOXP1 HIPK3 GLS PRSS12 ADIPOR1 FOXJ3 JAM3 RB1 RGCC TRAF6 HERC3 ADARB1 AGO4 RAB12 CCDC82 DGKE LIN7C ZSWIM6 RUNX1T1 ZNF423 HAUS2 RRM2B KLF9 UHRF1BP1L ARNTL SOCS5 FBXL3 FAM49B SPAG9 UBQLN1 PER2 DOCK9 MARVELD1 PDE3B NR1D2 VIM CTBS CEP57 PIK3C2A GCA LYAR N4BP2L1 PPP2R5A SLC6A6 CALM2 FAM76B CNOT6L CDKN2AIP NCOA1 RAB6A USP25 RBPJ CREBRF FRY GZF1 SAR1A HCFC2 SRSF3 TMTC1 LRCH1 ZFP91 NSMCE2 ETS1 BMP3 NXPE3 UHRF2 APBB2 RCAN1 EEA1 FRYL CREB1 FSD2 RC3H1 PDZD2 ZNRF3 THSD7B PREX2 NIPSNAP3B ZNF407 CELF2 NAP1L5 MME STRN ABHD13 MAP3K2 PCDH17 ATXN1 PHF19 GNB4 BRI3 ANKRD13A STON1 STK40 NPTN CLASP2 RIMKLB KANSL2 KIF17 PLAA ADAM10 ARPP19 RBL2 RNF138 SESN1 PCM1 ABL2 CTTNBP2NL SFT2D1 TFPI IER5 PIP4K2A DIXDC1 CYP2U1 ZDHHC21 RBMS3 MBD5 HNRNPC TTC28 MAFK RNF38 ST6GAL2 TMEM87A TLK2 RORA ITCH DOCK4 GSPT1 SCLT1 AFTPH UBE2V1 PSIP1 HERPUD1 KALRN TBPL1 SPPL2A TMEM30A HIPK1 ATF2 USP30 LHFPL2 CLOCK MAMDC2 SLC38A2 KMT2E NDFIP1	down	*
TET1_TARGET_GENES	0.0037780	0.0347211	0.4317077	0.2454897	1.254526	1037	CPNE4 RIBC2 ONECUT1 CA9 GPR89A IGSF9 HJURP DNAH2 PARPBP TFAP2A PROM1 NEK2 COIL UCHL1 DROSHA C17orf75 PAIP1 SORD THEM4 CDCA7 SIX4 TUBB2B GINS1 AGFG2 ASIC1 ANLN CCDC14 POLE STIL DGCR8 NUF2 AURKB CENPA PTTG1 WDR70 TMEM254-AS1 CDC6 ZNF714 STRIP2 CDC25A PLS1 TDRKH COPB2 KIAA0895 LIPE-AS1 CAND1 NCAPD2 SPDL1 UQCC1 LSM5 DNAI1 RUVBL2 SOX30 OSBPL2 CHAF1A ZFYVE27 GFPT1 ZNF850 DCBLD2 SPAG16 QTRT1 STAP2 PCCB COPG2 MAP3K13 KIF3B EME1 SPTB PCDHGC4 C20orf96 SAE1 ATR GTPBP3 TMEM132A IRF3 ZNF174 HYDIN ICA1 COASY DPCD TTLL12 MMS22L CDCA5 AKAP1 ADM2 RAD54L MRPL27 ANKMY1 SEC61A1 TARS2 LETMD1 PPP1R35 TMEM200C TOPBP1 ZYG11A PEX26 NFYA GAS8 RAD51AP1 EHHADH ABCB9 DNAAF3 TBC1D8 CAD ETFA SPAG8 OGFOD2 FADS2 KLHL3 NOL3 CNOT3 HSPBP1 CNPY2 SKP2 TNIK GPX8 TTBK1 ISOC2 TERC CMAS ANAPC5 ING4 RNPC3 CDK12 SRRM2-AS1 TNFRSF21 FAM135A MERTK CENPH ZNF260 NUDT2 KIAA0753 PHF12 ZSCAN25 ANKRD54 NAV2 POC5 NCAPG STX18 KCTD13 DHX37 TRIM41 ENPP3 ITPKA FEN1 TSPAN31 CNOT11 TMEM79 LRRC42 RAB11FIP4 SLC12A8 OARD1 TMEM120B SNRPE ZKSCAN5 RANGAP1 MZT2B ILF2 THNSL1 ATP7B SMG5 NDUFA11 C19orf47 DHX40 GALK2 TSNAXIP1 AGL JOSD2 ADAT1 NINL EFCAB2 POLL RAD9A COG2 KIF22 IQCG CCDC130 TMEM237 ROGDI COPS7B ZNF544 CHTF18 CSNK1G1 PDRG1 PCDH9 ZNF300 TJAP1 ITFG2 STX18-AS1 ENOSF1 GFM2 TM9SF4 BCL2L12 MAGOHB TYRO3 CABLES2 ELAC2 CNDP2 CCT7 SLX4IP RAD50 RNF187 TADA3 ZNF782 CENPV TUBG2 EFHC1 GPATCH4 FAHD1 MRPS23 RPUSD1 GMPPA FANCM MCM6 METTL2B EML6 PPCDC CKAP2 ZRANB3 C5orf22 LANCL2 LTV1 EIF3D ZSCAN32 SNX11 STMN3 NDUFS7 MYEF2 MRPL51 PIGX PDIA4 TMEM254 GOSR2 ZNF286A ZKSCAN7 ZNF224 CYTH2 RPS26 NCDN DOCK3 TRERF1 BBX PLSCR2 DENR CDC42BPA RFC5 WDR77 BMS1 ENKUR MLLT1 GTF3C5 KIAA0825 TMEM44-AS1 SNRNP70 SNORA14B ETHE1 AURKAIP1 VDAC3 TNS3 SLC12A2 ARHGEF39 ZNF131 SYNRG B4GALNT3 BCL6 GOSR1 XPC TCF3 POLR1A ZNF793 PFDN4 MTHFD1 TP53 PDZD7 LRSAM1 MON2 PRPF3 TMEM9B-AS1 EPHB4 DCDC1 NCAPD3 BCAT2 SART1 NUP210 MRPL48 ATF7IP IMMP2L FAM219A TIPRL PCTP PRKAG1 TMEM169 PHRF1 TEX9 LMBRD2 KIAA0586 TOMM7 RTN4IP1 ZNF554 EIF2D RPL23A VPS26B DCAF16 MRTO4	up	*
GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND	0.0036359	0.0338035	0.4317077	-0.2060338	-1.253215	534	SLC6A4 GPD1 LPIN2 PPARG CPEB2 IL1B LHCGR ADCY9 P2RY1 ADCY4 RAPGEF2 PTPRE PID1 KL PCSK9 FOLR1 FYN LPL RGS9 INPP5K CAV1 BAIAP2 AQP9 VAMP2 PRKAR1A PDE2A CD36 MIR146A ATP2B1 RRAGC RAP1A ANXA5 KLF10 CAV2 ADIPOR1 NR4A1 ADRB2 NFE2L2 NDEL1 LAMTOR3 CRK SFRP1 ZEB1 ARHGEF2 PDE4D ATP6V1H TMEM38B ATP6V1B2 FOXC2 ROCK2 STAT5A RAB12 FOXO1 SRSF5 SORBS1 PTAFR KLF4 ROCK1 KLF11 SOCS2 ATP6V1D ATG7 SSH1 NFKB1 PDE3B P2RY2 SIK2 VIM ATP6V0D2 TLR4 PIK3C2A GNAQ GNAI2 TBC1D4 BACE1 ACTR2 SLC25A33 PDK4 KANK1 MYO1C SLC8A1 ADCY2 PSEN1 SOCS3 APPL1 RAB8B CPEB4 GABPA RAB31 USO1 HRH1 ATP6V0B PALM RAPGEF1 PIK3R1 GRB2 CREB1 RAB8A PRKACA RALB ATP6V0D1 RHOQ KLF2 FOXO3 PKD2 TREX1	down	*
BARX1_TARGET_GENES	0.0042396	0.0378744	0.4070179	0.2447835	1.249706	1018	COL17A1 TSPAN8 PDE11A FOXA3 CDH17 HJURP RUVBL1 CEP89 CDC45 TICRR DNAH2 BUB1B CCDC127 NEK2 CENPF COA1 PSPH SLC2A1 DDIT4 NDC80 TTC25 PIF1 DEPDC1B GINS1 CDCA2 EFNA3 PRR15L IQGAP3 UBE2Z EIF2B5 ANKRD24 FLAD1 PLK1 NUF2 YEATS4 EFNA4 CDCA8 CENPA TPX2 BCL2L14 XRCC2 TDRKH CCT6A GON4L XPOT ZWINT KAZALD1 TAMM41 FAM220A HAUS5 TJP3 RSPH1 POLR3A BZW2 EXO1 RAB11B-AS1 XPNPEP3 SDHA ZFYVE27 MRPL15 POLM COPG1 AP4M1 WASF1 KIF3B TOP2A EME1 IQCD PMS2P4 THBS4 METTL7B SAE1 LARS2 MCM7 ZNF860 POC1A RSRC1 TPCN1 RRM2 CDCA5 MRPL27 BLOC1S1 ZNF785 AP1M2 ZNF786 ACTL6A NFYA PSMD4 DCTPP1 TIMM50 ZNF48 SPATA17 EHF SYMPK FBXO16 ARL16 ALDOA PIGO TULP3 R3HDM2 PPP1R37 INCENP RBAK CKS1B ISOC2 CDKN2C PPIL2 TMEM106C ANAPC5 PABPN1 HDGF CDK12 WDR5B SSBP1 MCTP2 SRRM2-AS1 KCTD7 CCT3 EEPD1 GMNN SUN1 POC5 ITGB8 ACP6 GIPR SMG9 PMEL RNF181 ZNF584 TSPAN31 ZNF775 TMEM79 SPAG5 LINC00649 OARD1 MTBP C9orf43 ANXA2R IFT52 UBN2 UNC45A EIF6 DHX34 POLR2H GIPC1 DNMT1 ILF2 DLGAP5 CCDC134 SMG5 NDUFA11 SLC26A2 FAM47E-STBD1 AGL MTOR PUS1 MAN1B1 PSME2 TRIM37 DUSP12 FBXO15 PPOX NFATC4 CENPQ RHBDD3 CSNK1G1 SOX2-OT OS9 CCDC146 HECTD1 GEMIN5 ITFG2 SLC4A2 DNMBP SND1 CDK13 PRRG2 ZBTB45 ENC1 NIF3L1 SLX4IP NR6A1 ABCC10 FAM71E1 SUPT16H STAG3L4 LIMA1 CKAP5 L3MBTL2 PWWP2A CDC20 AAAS CCDC30 SIRT4 EFHC1 ASCC1 ACLY PPP6R1 FITM2 SRRT ABCA7 CLINT1 KRT8 MRPL24 PEX5 KDM4B BLCAP METTL2B ZNF446 DHX8 NOSIP NMNAT1 EIF3D SCYL3 HAX1 C1orf109 HOXA-AS3 AATF DOLPP1 DUS4L HAUS4 LSM4 TXNL4A RNF31 STK35 MST1P2 DUS2 SPSB3 NUP62 DPH5 AMN1 PMS1 B9D1 CYTH2 ADM CISD3 GTF3C2 SNRPD2 DOHH PAK4 ABCF2 CCDC9 PRPF31 CLUAP1 INO80E NUBP2 OSBPL10 TNKS1BP1 TRAPPC9 TOMM40L RNF123 PFKM ARHGAP11A TAB1 SAMD4B RPRD2 IKZF4 CDK5 FAM118B MXD3 UQCRQ ZNF131 SIRT6 BCL6 CENPE ANKMY2 DNAJC14 HGS UBE2C TTC9C NCAPD3 BTN2A1 TUBA1C ZSCAN20 ATF7IP TAX1BP1 DNM1L CLASP1 NUP93 SCAF1 MOK MZF1 C12orf10 TRAPPC6A SETD5 TIPRL FBXL18 PRKAG1 ALKBH2 PHRF1 RPUSD3 FAM47E VPS26B PLAC8 VPS18 SETD1A WDR55 MBTD1 DEPDC4 ASB16-AS1 PPP1R13L METTL4 SH3RF2 UTP18 PTPRK PARL MST1 RPL36 FOXP2 ZNF514 PSMB10 MRPL43 ABHD2 TNPO3 NFE2L1 USP35	up	*
MIR548AH_3P_MIR548AM_3P	0.0017999	0.0197343	0.4550599	-0.2022279	-1.248869	680	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C RAB3C FYN CCL3L1 QKI GTF2I DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ZEB2 ARHGAP29 CNST STARD4 MCTP1 HBEGF TM2D3 ADAM17 ACOT2 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L PPP3CA TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FBXO8 FLI1 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 AFF1 BACE1 CNOT6L LIN7A STK24 USP25 SERTAD2 UFM1 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM YBX1 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 CPEB4 KCTD12 ETS1 MED30 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS PELI1 AGPS CDK17 YTHDF3 PKD2 NAPG MAPK8 BTBD7 ING3 MME AZIN1 DCK SERPINB1 PDS5B ABHD13 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 VPS4B CYP2U1 ARL14EP UBE2D1 ZDHHC21 SSH2 SOAT1 KPNA4 RBMS3 SCAI PAK2 SKI CECR2 FAM126B MMD CAMSAP2 C21orf91 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	*
CREB3L4_TARGET_GENES	0.0026667	0.0265560	0.4317077	0.2438356	1.248487	1161	COL17A1 ANKRD18A PRLR FAM201A MUC13 ZDHHC8P1 HOXB-AS3 CNGA1 WFDC3 RPGRIP1L NEK2 COIL CYP2J2 PSPH TTF2 GCNT3 THEM4 CDCA7 ECE2 TMC1 GINS1 CDCA2 CDK4 PRR15L BCL2L15 NAALADL2 FLAD1 SAP30L-AS1 DGCR8 YEATS4 AURKB ALDH18A1 PAK6 CCNB2 ACER2 SLC35E3 BCL2L14 RAD54B TYMS GRHL3 ZNF117 FERMT1 ERV3-1 GALNT10 EIF3B CIB1 TMCC1 CCT6A XPO5 KIAA0895 LIPE-AS1 GINS4 KIF27 RCCD1 XPOT ZFP64 ZWINT NUB1 KAZALD1 MAGEF1 AARS2 WDR62 CLPTM1L CASP2 ZNF391 TP53BP1 AURKA THBS4 NDUFS2 SAE1 POLD2 SFI1 SMARCAL1 KIF2C ZNF860 MPHOSPH9 RRM2 RGL1 LIPE SETDB1 ZNHIT6 AMACR PKM WDR73 LMNB1 CDC25C XXYLT1 EMG1 ZNF785 RNFT2 LRRC66 PSMG4 OAZ3 CD24 CHEK1 SCAMP5 SRD5A3-AS1 CENPO COX19 ZKSCAN1 SPATA17 FNTB REPIN1 MRPS30 LRRC45 SLC18B1 COMMD4 C2CD3 FBXO16 DET1 NIPAL1 ALG3 PIGO SPRY1 SRRM5 R3HDM2 CNPY2 PPP1R37 CASP6 KNSTRN RASSF6 CAPN8 PPIL2 NUSAP1 TMEM106C CDK12 PPIC DNTTIP1 KCTD7 FAM135A PICK1 ESRP1 GOT2 DIS3L2 OAT NPM3 VPS28 CCNJL L2HGDH DGAT2 PMEL ENPP3 ITPKA PDK1 EZH2 ACTR3B METTL3 RNF207 SF3B3 TNRC18 LCA5 ATAD3A GOLGA5 NLN HMGXB3 PBLD PSMC4 TSPAN1 CENPP UBN2 EIF6 RNF44 EFTUD2 NET1 DNMT1 GOLGA3 ELMOD3 PELP1 ILF2 RHOC COL1A1 VIPAS39 SCLY CCDC134 PSMA5 PUS1 EFCAB2 MNS1 MAN1B1 LLGL2 S100A16 ARHGAP32 TRIO OSBPL3 PTGES2 PIGG HIRA MRPL52 UBE3D TIGD6 CCDC130 COX7C FBXO15 DPH2 AKAP8L MLEC MSI2 LMTK2 ANP32E PKP4 NUDT16 PRMT7 TM9SF4 ANAPC1 COG4 TSEN54 ZNF282 NUP85 FAM200A ZBTB45 PPME1 GALNT7 CLTB TMEM232 CCT7 ANKRD31 KLC2 BAZ2A FAM71E1 TADA3 LSG1 LINC00910 CPSF4 PWWP2A DGKA STOML2 AAAS CA11 GBF1 MAN2A1 C12orf65 ZNF616 MRPS23 PPP6R1 SRRT PHYKPL KRT8 ASRGL1 MCM6 KDM4B CYP2S1 ODF3B XRCC4 MCM5 RPPH1 USP21 WDR35 ACOT11 ZRANB3 DDX23 HAUS6 RABEPK SLC35A3 HAX1 C1orf109 SNX11 AATF EXOSC5 MRPL51 CCNG1 RPP38 SF3A2 CDH11 TSR1 TCERG1 COPZ1 ALG8 EPCAM LRRC14 AMN1 GLO1 B9D1 TM7SF3 CCNA2 SMARCA4 DBNL CISD3 DDX54 DENR RFC5 DOHH BLVRB ACKR2 CEP164 WDR77 VPS33B OSBPL10 RAD51 TTC1 ZNF384 CHMP1A ARHGAP5 ARHGAP11A SCOC MRPL9 RDH10 PAXIP1 SNRNP70 NME7 VPS9D1 ACP1 FAM118B SNX8 DIP2B UQCRQ ZNF131 TCF3 PFDN4 GLYCTK MTHFD1 TIMM44 CCDC122 SLC36A1 PPIA UBE2C PTOV1 NELFA SFXN5 ULBP3 ENO1 RAD1 MUC1 COX6B1 RNF32 NUP93 THRB-AS1 DDX41 BRIX1 C12orf10 MSANTD4 RAD51-AS1 PRKAG1 GEMIN2 PARP2 PCGF6 CLNS1A TTC5 TFB1M CSTF1 FAM47E RTN4IP1 ZNF740 VPS18 PDXP WDR55 MED22 DHDDS DEPDC4 MAN2C1 MED15 SH3RF2 ASPH TRIM52 PTPRK PRPF19 TMEM259 DEPDC5 FOXP2 ZNF276 PSMB10 ZNF688 LGR4 SDHAF1 TNPO3 USP35	up	*
MIR548J_3P	0.0039320	0.0358124	0.4070179	-0.2010435	-1.248213	682	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C RAB3C FYN CCL3L1 QKI GTF2I DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ZEB2 ARHGAP29 CNST STARD4 ASAP1 MCTP1 HBEGF TM2D3 ADAM17 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L PPP3CA TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FLI1 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 AFF1 BACE1 CNOT6L LIN7A STK24 USP25 SERTAD2 UFM1 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM YBX1 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 CPEB4 KCTD12 ETS1 MED30 OSTM1 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS PELI1 AGPS CDK17 YTHDF3 PKD2 NAPG MAPK8 BTBD7 ING3 MME AZIN1 DCK SERPINB1 PDS5B ABHD13 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 VPS4B CYP2U1 ARL14EP UBE2D1 ZDHHC21 SSH2 SOAT1 KPNA4 RBMS3 SCAI PAK2 SKI CECR2 FAM126B MMD CAMSAP2 C21orf91 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	*
GO_HEART_DEVELOPMENT	0.0045185	0.0396937	0.4070179	-0.2108820	-1.247057	476	SMAD6 RBP4 HSPB7 TMEM100 ACVRL1 FOXF1 SOX18 TEK PDLIM2 DLC1 CCM2L PPARG TBX3 RAMP2 BMP2 SIK1 ENG FOLR1 SOX17 CITED2 CALCRL BMPR2 S1PR1 PRKAR1A MEF2A CDC42 TGFBR3 TGFBR2 SCN5A HEG1 PDE2A KCNAB1 JPH2 TBX2 LMNA LUZP1 GATA3 RB1 WNT3A HNRNPU TCAP FOXC2 NODAL ZMIZ1 MMP21 ROCK2 SNAI1 TNNC1 EPOR REST ID3 ROCK1 GAA ADAMTS9 CLDN5 SEC24B CDKN1A ID2 MIR24-2 SMAD7 ZMPSTE24 ADIPOR2 MBD2 TBX5 MYH11 DCHS1 HES1 MIR17HG TGFB2 SRF RBPJ SLC8A1 PSEN1 JUN NOTCH1 ADRA1A CREB1 TBX21 NDST1 NDUFV2 CACYBP PKD2 TREX1 WNT11 SYPL2 SAV1 TGFB1 JMJD6 MIR23A PDLIM1 PIM1 MEIS1 MYOCD GATA6 ACTN2 RGS2 LTBP1 KAT2B PRICKLE4 RXRA SMAD2 FGF2 PDLIM5 FKBP1A ARRB2 OSR1 SETDB2 RTN4 TAB2 PTCH1 ACACB PARVA STK4 EDN1 SCUBE1 PTEN SYNPO2L FGFR1 MIR548C NRP2 NRG1 ZFPM2	down	*
GO_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS	0.0025775	0.0259403	0.4317077	-0.1998244	-1.242576	693	GPD1 TRIM71 MGAT3 HMOX1 ABHD5 RASIP1 CSDC2 TMEM150B IL1B ATXN3 RDX PCSK9 SNX32 ECSCR CAV1 MYD88 PAFAH1B2 PSMD5 SLC11A1 TRIB1 RCHY1 EDEM1 MIR146A FBXO7 RRAGC BTG2 HSPB1 RNF144B FAM122A ADRB2 NFE2L2 LAMTOR3 HNRNPU MCL1 ATP6V1H APOC1 ZYG11B ATP6V1B2 CST3 FBXL5 EXOSC9 IL10 ROCK2 RAB12 FOXO1 SDCBP MEFV YBX3 RNFT1 ROCK1 DAB2 DRAM1 CEBPA ATP6V1D SOCS5 EPM2A UBQLN1 ATG7 VIM C9orf72 ATP6V0D2 TAF9 RNF139 SMAD7 ZMPSTE24 CPT1A PINK1 EXOSC8 HTT N4BP1 CNOT6L PIAS1 USP25 MYLIP DCP1A IL6 RYBP YBX1 GABARAPL2 PSEN1 NKD2 PIKFYVE PSMA1 ADRA1A ATP6V0B HSPA1B PLK3 MTMR9 VPS26A TBC1D12 BAG5 DAPK2 PABPC4 UBAC2 HERC1 RAB8A RC3H1 PRKACA NUDT15 UVRAG YWHAZ RALB SNX9 GRSF1 ATP6V0D1 UBB PNPLA2 TNFSF13 YTHDF3 USP7 PSMD12 FOXO3 PRKCG MAPK8 KAT8 HNRNPD TIMP2 TFEB SMCR8 METTL14 MTMR2 YTHDF2 PDE12 NLRP6 ATP6V1A CBFA2T3 ZC3H12D IRS2 CNOT7 ATP6V0C SLIRP CD81 EXOC1 BAG6 TOB1 CSNK2A2 TSPO BNIP3L SESN1 ABL2 RAB5A PIP4K2A HSP90AA1 CALCOCO2 EPHA4 TAB2 RIPK2 ARIH1 HSPA8 ACACB PSME4 ULK2 BOK DAPK1 SREBF2 HNRNPC CTSC TIMP3 PTEN THRAP3 TLK2 ITCH LDLR PSMD6 PSMD9 CNOT8 ZFAND2A PUM1 FEZ1 FEZ2 EIF4G2 PPP1CB VPS13D ATP6V0A1 KAT5 HERPUD1 HTRA2 NAF1 USP30 FUS TREM2 SH3GLB1 RB1CC1 DRAM2 EXOC8 ZFP36 BBS7 PIK3CG YWHAB MUL1 QSOX1 WDR41 CHMP4A LAMP3 LAMTOR5 WAC UBE3A	down	*
MIR4698	0.0059688	0.0487219	0.4070179	-0.2048093	-1.241224	533	RTKN2 COL25A1 SECISBP2L CPEB2 KL ARRDC4 OTUD1 CCDC88A SEC22C CALCRL QKI CDH13 ADRA1D ZCCHC2 MTMR10 KCNN3 NEDD9 TSHZ1 TET2 ASAP1 C1orf21 BZW1 SERINC1 NLK FZD4 REV3L CAV2 PAG1 STOM FOXJ3 SRSF2 SPTBN1 ANKRD29 EPM2AIP1 UBE2D3 TMEM38B KDSR MSR1 SNAI1 RAB12 PTPN21 FOXO1 SGTB SORBS1 LIN7C UHRF1BP1L OSTF1 GRK5 CLIC4 NPR3 KIF26A UBQLN1 UBE2E2 TEF CAPZA2 CCSER2 ELMSAN1 GCA MBD2 PPP2R5C KIAA0408 PAFAH1B1 FAM76B HSDL2 CNOT6L LIN7A ACTR2 STK24 LIN54 CLN8 SNX3 MOB4 MYLIP CDC40 PHTF2 APPL1 PLEKHA3 UTRN HMBOX1 CPEB4 CUL4A JPH1 ELOVL7 SP3 PABPC4 PI4K2B FRYL CREB1 COBLL1 RC3H1 FSD1L RBM22 PREX2 RASSF2 EPC2 CELF2 BLOC1S6 CTTNBP2 PELI1 CDK17 PTP4A1 MAPK8 NAP1L5 TCF4 PDS5B YTHDF2 SKIDA1 ZBTB11 NAB1 MAP3K2 MACF1 MBNL1 ATAD2B ARPP19 AMD1 NEK1 PDLIM5 CTTNBP2NL TFPI CDC42EP3 TPT1 SLC25A20 TAB2 USH2A PSME4 G3BP2 SSH2 KPNA4 RBMS3 PLGRKT HNRNPC LIMCH1 RASSF8 TTC28 ACADM SCAI RORA NDUFAF5 DNAJA2 SPATA13 ZBTB44 GPALPP1 MAP4 ACVR1C CDC14A GHR SAP18 TMEM30A SVIL HIPK1 ATF2 UBA6 CLOCK SLC38A2 KCNJ1 CSNK1G3 PRTG XPO7 C6orf62 UBE2W FAM160B1 SGIP1 UTS2B KIDINS220 AKAP12 TSC22D2 HMGB1 ARHGEF12 CUL2 CRIPT DR1	down	*
THAP1_TARGET_GENES	0.0026084	0.0261993	0.4317077	0.2399138	1.237480	1589	MIR210HG WFDC3 RUVBL1 CDC45 MCM10 DEPTOR C5orf63 ABCA17P COIL CCNB1 DROSHA C17orf75 GBAP1 NUDCD3 TTC25 MKS1 CCDC113 TBRG4 AGFG2 RACGAP1 LRRC37A3 ANKRD24 NDUFS6 NUF2 WDR70 RAB36 UMPS CKLF-CMTM1 COCH PRC1 ORC1 ACY1 CIB1 GON4L MIS18A ZNF3 KIF27 RCCD1 XPOT DNAH14 UQCC1 WDR90 AARS2 SIPA1L3 TOP3B RANBP1 CEP250 CLPTM1L C5orf34 NEURL2 DNPH1 CISD1 SMARCC1 RPL39L BBS1 C9orf116 BOD1 QTRT1 CUL7 KIF15 FOXJ1 AP4M1 FRS2 TIGD4 EEF1E1 RPL32P3 CENPL RFXANK AURKA NUP155 WDR3 NDUFS2 ATR YKT6 GTPBP3 KIF2C MCM7 RSRC1 COASY ABCC5 RNF157-AS1 NSUN2 CDNF CCDC114 FANCD2 TRPT1 ZNF226 EMG1 ZNF785 PYCR2 SLC37A3 WDR60 EME2 ZNHIT1 BCL2L2-PABPN1 C7orf50 IFT172 HSF2BP TRMT61B SRD5A3-AS1 CENPO COX19 TRMT2A AKT2 B4GALT7 GEMIN7 EEFSEC CAD ZNF507 FNTB SAMD10 SLC35E2B PROB1 ZNF713 HSPBP1 COQ9 SKP2 RECQL5 DHRS13 CKLF GEMIN8P4 CKS1B MRPL36 EFCAB11 CDKN2C HPS4 MEA1 DDX51 HARS2 ASF1B ANAPC5 ING4 PABPN1 POLE2 DNTTIP1 EXOSC2 DIDO1 WDR54 PHF12 DCBLD1 TYW1 RBCK1 STX18 REEP6 PSMB5 MCAT MRPS2 PRPF6 AP5Z1 PMEL PODNL1 TRIM41 ENPP3 ZNF584 PSAT1 DPH7 KRBA1 TMEM79 ACTR3B LINC00649 FADD METTL3 RAB11FIP4 USP42 ATAD3A TTC16 HMGXB3 CCDC57 FAM102A PSMC4 CENPP SRD5A1 PA2G4 TPD52L2 FAM86C1 EFTUD2 CHCHD2 MZT2A DNMT1 PARS2 CATSPERG MZT2B G6PC3 ZGPAT ILF2 ARFRP1 CCDC142 TSPAN17 PABPC1L POFUT1 TUBG1 DCLRE1C SCLY SMG5 WDR53 ARHGEF16 NFS1 UBAC1 GALK2 ENTPD3-AS1 PSMA5 TRMU ADNP DNAJA3 NMRAL1 TACC3 MAN1B1 RAD9A MRPS34 LONP1 GALNS DHODH PKP3 PIGG HIRA TIGD6 CCDC130 LMF1 FBXO15 UBE2Q1 PPOX CHTF18 PCSK4 STOML1 MSRB2 JMJD4 ESCO2 MLEC OS9 MRPL4 PCDH9 STX18-AS1 LIN37 ASNS TM9SF4 ANAPC1 C15orf41 CKMT2-AS1 NRF1 POLD1 C12orf73 GNAZ PEX10 ZBTB45 TAPT1-AS1 NAIF1 COPS6 CCT7 YARS2 ARHGAP12 SLX4IP RAD50 CCDC137 ABCC10 SASS6 EPN1 KLHDC3 SH2B1 TADA3 PTER EP400 FN3KRP CPSF4 COG1 TMEM106B AHCYL1 WDR34 NPRL3 PPP1R8 EFHC1 FAF1 DUS1L RRP9 MRPS23 ACLY ZNF497 RPA1 PPP6R1 FIBCD1 RPUSD1 ARHGAP22 BAD ABCC3 MADCAM1 CDK5RAP2 MGME1 ZNF160 GID8 ZSWIM8 XRCC4 SLC38A7 ROMO1 NOC4L USP21 KPTN NMNAT1 CD2BP2 TDP1 SIRT5 DDX23 SNAP47 C5orf22 LANCL2 PYGO2 EIF3D SCYL3 URB1 NFE2 SNX11 ADCK1 KATNB1 NEURL4 DUS4L POLR3E IGHMBP2 TXNL4A AP4B1 PPP1R3E SH3BP5L LHPP RRP36 DDX55 CEP152 MST1P2 ALG8 SPSB3 PRMT5 TMEM17 NDUFV1 COG5 AMN1 TSPAN10 ZNF212 RPS26 RRNAD1 NCDN SMARCA4 ULK4 SLC2A5 ECH1 ZNF445 GTF3C2 MANBAL CANT1 PDF POLR3B MRPL55 CSNK1G2 TXNL4B AMDHD2 PCBD2 CTU1 ZNF436 CDK5RAP1 TTC31 CCDC9 ACSF3 NUBP2 HOOK2 N6AMT1 ZNF384 ZNF292 SEC13 TOMM40L RNF123 KCTD21-AS1 MARK4 SUPT3H SAMD4B SRP9 MRPL21 SNRNP70 VPS9D1 ACP1 FAM118B DNPEP SNX8 RHOT2 AGBL5 TMEM101 AURKAIP1 CASC2 CIAPIN1 SIRT6 GNA12 POLR1B TARBP2 MAPK8IP3 POLR1A EIF4G1 DNAJC14 E4F1 MPG RHPN1 SMPD4 ZMAT2 NDOR1 ALG1 TP53 LRSAM1 CELSR3 MON2 GDPGP1 ZNF341 KDM5B CHERP RANBP3 SNRPC PPIA TBL3 DCDC1 TTC9C PTOV1 RHPN1-AS1 FBXO45 RFT1 MRPL20 PWP1 ZSCAN20 RAD1 E2F7 TAX1BP1 NAT10 COX6B1 THAP3 PIAS4 TK2 TRUB2 RCBTB1 LINC00888 DDX41 MTG2 BRIX1 MZF1 MSANTD4 MAP2K2 PRKAG1 SNAP25 LMBRD2 PCGF6 FAM86C2P SLC33A1 CSTF1 ZNF630 DNAL4 RTN4IP1 EIF2D ZNF740 LASP1 NOS3 MORN4 POLRMT PDXP MED16 DNAAF1 LUC7L3 DHDDS DGUOK MAP3K12 MAN2C1 SPHK2 TOP3A VPS16 MED15 C7orf25 RAB40C RUSC1 TRAFD1 NELFB EIF2B1 PARL DSN1 MST1 CDK11B TMEM259 RPL36 NOXA1 NUDT22 SRI PPP2R5E ZNF276 ZNF514 ZNF688 SDHAF1 NFE2L1 GGA1 OPA1 ZNF579 AP2B1 TMEM9 BAK1 TMPO TOMM40 TM9SF1 CTU2 SRFBP1 MRPL45P2 IMP4 MTMR4 GCC1 DCLRE1B TEFM ZNF425 URB2 ZNF638 AK9 GAK ARFIP2 TMEM167A ABCD3 AP1B1 SLC27A5 TTPAL DGKZ TRIM59 CACTIN IMP3 FNTA CS ZNF524 AP2A1 CCDC86 TMEM144 PLOD3 TMEM175 TAOK2 SPRYD4 C1orf74 ELP6 UVSSA E2F4 PPP2R1A ZC3H18 SLC35B4 TMEM219 DHX38 GORAB COX6A1 B3GALT6 METTL17 EVI5L NUP214 SLC44A1 C15orf40 EPS15L1 CCDC124 GRHPR PACRG PTPN23 COQ4 COPS7A ZNF839 ZNF664 METTL9	up	*
MIR8485	0.0026406	0.0263573	0.4317077	-0.1976426	-1.236510	852	SMAD6 AJAP1 COL25A1 SCN4A C2orf91 DLC1 ADPRH TAL1 ZC3H12C SPN P2RY1 PTP4A2 RDX CLEC12A DPYSL2 BMPER MBOAT2 CYP4B1 RAB3C BTNL9 BMP2 SIK1 ZBTB34 ARHGEF15 IBA57 BACH1 LONRF1 CORO1C MYADM CRY2 FLVCR2 VAMP2 ADCYAP1R1 ARL8B DYRK1A MEF2A KCNN3 VAPA CBL ZBTB2 FAM49A GGA2 SEMA6D ZBTB4 CD36 UBR3 KIAA0355 PLA2G7 LIFR TNIP3 RNF144B NLK SPIRE1 FOXP1 KLF6 SLC7A11 ADRB1 SLAIN2 FOXJ3 MOB3C PLXNA4 SLC25A37 CD93 LAMTOR3 PPP1R13B ZYG11B SLC7A2 STAT5A AMOTL1 NRARP TIMM10B FOXO1 TBX4 SDCBP ZSWIM6 ZCCHC24 HAUS2 MVB12B STK17B ADAMTS9 SSH1 P2RY2 NPAS3 PTPRC CXXC4 RECK LBH ELK3 EVI2A PPP2R5C PEAK1 SLC6A6 UNC5A KIAA0408 CYP26B1 PRDM5 NUS1 AFF1 CRIM1 SEC31A RASL12 AFF3 SIAH1 TGFB2 PIAS1 CLN8 SRF PDK4 SPIN1 MOB4 RBPJ SLC8A1 FLT1 METAP1 SYNPO2 PKNOX1 MED28 SGK1 KIF13A HSD17B13 EBF2 NEK7 PDCD6IP CNTN3 AQP3 C2CD2 VAT1 WSCD2 ETS1 DESI2 CELF1 JUNB ARHGEF10 RABGAP1 UHRF2 MTMR9 IQSEC3 SKIL ENPP4 HUNK PIK3R1 HSPA13 DDX5 GRB2 THUMPD1 FRYL COBLL1 SIGLEC15 ATP13A3 RASSF2 CASZ1 TIGIT SNRK MCAM ATP6V0D1 AGPS PNPLA2 NECAB1 USP7 CCDC85A DGKG ZFAND6 SORT1 FXYD6 DDHD2 STRN AP1G1 PHF3 KIAA0232 NDUFA5 CCP110 GNAI1 NAB1 C16orf72 DYNC1LI1 CNOT7 MAP3K2 NFYC GNB4 ADPGK THAP11 ACYP2 SPOCK2 TCF7L1 SMAD2 INO80D JUND RNF138 ABL2 GSTM5 CTTNBP2NL ADAMTS4 SEC63 PIP4K2A CYB5R4 TMOD2 EPHA4 ARIH1 PTCH1 ILKAP IPO5 MEGF9 ZDHHC21 SSH2 ISCU KPNA4 PARVA CD19 STAM2 ANKRD49 SIN3A RNF38 PTEN DNAJB9 TLK2 FAM126B TNFSF9 SYNPO2L C21orf91 RORA COL13A1 DAZAP2 NRP2 DOCK4	down	*
GTGCCTT_MIR506	0.0034939	0.0329134	0.4317077	-0.2029839	-1.234121	615	RAB11FIP1 SEMA6A ABHD5 EDNRB TAL1 OSBPL11 KLF13 ADCY9 CLDND1 EGR2 DDX6 CAV1 MYADM THAP2 QKI CTDSP1 NR3C1 TSHZ1 CBL USP47 MOB1B GGA2 DNAJB14 LRRFIP2 EDEM1 SEMA6D SLC44A2 SH2B3 NFIX TTL PCYOX1 CYB5A BTG2 ZDHHC2 FZD4 SPIRE1 CAMTA1 NR4A1 FAM122A ITSN2 TFRC PTPN12 TLE4 LRRC57 DENND6A ZCCHC24 FAM76A ADAMTS9 CEBPA SOCS5 GAPVD1 MYRIP ABCC4 ATL3 MGAT4A MARVELD1 CADM1 SIK2 VIM C9orf72 SHC4 CCND2 ELK3 WDR48 ZMPSTE24 ELMSAN1 N4BP1 PAFAH1B1 KPNA3 GNAI2 FAM76B RSRC2 C2orf69 SERTAD2 KANK1 CREBRF FMNL2 VAMP3 SCN4B TMOD1 PDIK1L NSMAF SGK1 PSEN1 RNF141 ARL5B MITF VAT1 HIC1 PDE5A DNASE2 RHOG RCAN1 WTAP PI4K2B GRB2 THUMPD1 GRASP RPS6KA1 FSD1L SLC10A7 FAM177A1 FSTL3 GFPT2 NDST1 PPM1F BLOC1S6 CD151 POGLUT1 GRSF1 ADNP2 PNPLA2 CD164 HIVEP2 YTHDF3 SRSF6 TRAPPC10 NAP1L5 BTBD7 TFEB AP1G1 DCAF5 VAMP4 TSC22D1 ZBTB11 GNAI1 PIM1 ORC2 PHF19 GATA6 SPOCK2 PDE4B RXRA PITPNA VPS4B TBC1D1 BRWD1 EPHA2 G3BP2 TMEM184B SSH2 GRIN3A KPNA4 TMEM109 DAPK1 NPAT LIMCH1 STK4 BCAT1 SKI ANXA11 NRP2 NR3C2 NAA15 IQGAP1 WDFY3 SPOPL EVI5 PAPSS2 FNBP1 PLAG1 CHP1 CHIC2 SPPL2A SVIL HIPK1 CLOCK MYH10 ITGB1 CMPK1 RB1CC1 ALG2	down	*
GO_POSITIVE_REGULATION_OF_CELL_DEATH	0.0048957	0.0420808	0.4070179	-0.2027113	-1.232525	603	NLRC4 KMO RAMP3 HMOX1 DLC1 SCIMP PPARG SFRP4 MNDA RAPGEF2 BMP2 SIK1 PCSK9 FYN HCAR2 ECSCR CAV1 FOSL1 HMGCR MAL CDC42 CASP12 CASP9 RHOA TXNIP CD36 ANXA1 HSPE1 MIR146A TNFRSF8 LATS2 CLEC7A PICALM ANXA5 RGCC TRAF6 GRN SFRP1 PPP1R13B WNT3A ARHGEF2 SOX7 ADAMTSL4 MCL1 NODAL PPP3CC DIABLO CASP5 RHOB IL10 ARRB1 MOAP1 FOXO1 KCNMA1 SAP30BP CASP1 TNFSF12 PLAUR REST ID3 KLF11 TNFSF15 STK17B THBS1 CTSD ATG7 CCL3 SSH1 CDKN1A PTPRC ATF3 ARHGEF26 TLR4 MIR24-2 DUSP1 INHBA PINK1 HTT BCLAF1 PTGIS TP53BP2 BACE1 NCOA1 SIAH1 TGFB2 BTG1 RPS6KA2 ARL6IP5 PRKRA PRDM11 IL6 RYBP CD160 NSMAF DDX20 PSEN1 C1QA JUN NOTCH1 PNMA2 CTSZ CARD8 TYROBP CYCS DNAJA1 APBB2 SKIL CREB1 MALT1 UNC13B YWHAZ TNFRSF10B RASSF2 APH1B PPM1F FOS UBB FOXO3 MAPK8 WNT11 ING3 SPOP IRF5 SORT1 SAV1 VAV3 PEA15 OSGIN1 APBB1 PDCD1 PPP3R1 SOD2 NQO2 GNA13 ADAM10 SERINC3 PPID TSPO BNIP3L C3orf38 TNFAIP8 CALHM2 ARRB2 TIAM1 RIPK2 NLRP3 BOK DAPK1 STK4 RET ADORA2A CTSC TIMP3 PAK2 PTEN P2RX1 SFPQ ATF4 ANO6 PMAIP1 SMPD1 SLFN11 ARHGEF18 HTRA2 KALRN ACVR1C EGR1 ARHGEF17 CTSH SAP18 ZBTB16 CDKN1B DUSP6 ATF2 PIP5KL1 DCUN1D3 ITGB1 PDCD2 S100A8	down	*
ZNF30_TARGET_GENES	0.0039434	0.0358688	0.4070179	0.2405113	1.231829	1189	SYT8 RUVBL1 CEP89 DNAH2 FANCI S100A2 NUP107 NEK2 DOC2A UBE2T ZNF280B C17orf75 FBXO27 GBAP1 PBK TTC25 TSFM SLC25A21 PHGDH C12orf66 CREB3L4 GINS1 AGFG2 LRRC37A3 UBE2Z NOL12 POLE SNF8 SDHAP3 NABP2 TTC26 NUF2 GPI WDR70 ZNF221 TIGD1 COPB2 KHDC1 GINS4 SMUG1 CDK5RAP3 AGK CYP3A5 NME1 AARS2 HAUS5 TOP3B CEP250 WDR62 TMEM41A ZNF862 EXO1 ZNF74 XPNPEP3 ZNF391 FOXA1 C9orf116 ZNF850 LINC00665 TRIM29 KNTC1 CCDC77 FBF1 BPHL MED12L SLC29A2 YKT6 GTPBP3 ASCC2 CENPW ICA1 RSRC1 COASY SPEF2 RBM28 CSRNP3 RNF43 ENTPD6 SBK1 FANCD2 MCM3 BLOC1S1 SNHG11 CDC25C EMG1 PYCR2 TARS2 ANG B3GNTL1 POLR3C EME2 LINC00265 MAD2L1 HSF2BP ABCB9 MDM2 THAP10 TIMM50 AKT2 B4GALT7 PKMYT1 GEMIN7 BRIP1 OGFOD2 RABEP2 PHB ALDOA MNAT1 SPRY1 SRRM5 OSBPL7 CNPY2 PPP1R37 DHRS13 DDX56 DCLK1 MSTO2P APLP1 SUPT5H ANAPC5 DMKN ZNF45 SSBP1 ZNF260 PHF12 ZSCAN25 DMGDH POLR3K STX18 DHX37 STAT2 MCAT MRPS2 TRIM41 ENPP3 KSR2 KRBA1 TMEM79 TNPO2 TTC23L LINC00649 TAF6 RNF207 SNRPE ABCA4 HMGXB3 PSMC4 VPS72 WDR24 ANXA2R SNRNP25 MYO19 DNMT1 GOLGA3 ZSCAN9 ZNF354A CATSPERG G6PC3 SPEF1 CAPS2 ILF2 GNPAT C19orf44 SMG5 NADK2 SEC16B C19orf47 ZNF233 TRMU ADNP MTOR DNAJA3 ZNF133 EFCAB2 MNS1 DHRS4-AS1 MRPS34 MC1R LONP1 ARHGAP32 COG2 HIRA UBE3D TIGD6 COPS7B TK1 C1orf131 CASP7 RHBDD3 JMJD4 MLEC MEGF8 MTND5P11 STX18-AS1 LAMTOR2 LIN37 DNAJC11 NDUFA13 KRBA2 GFM2 TM9SF4 ZNF282 KDM3B SIL1 FAM207A C12orf73 CCDC159 JTB SLC1A3 ATAD5 ENC1 NIF3L1 RAD50 CCDC137 SASS6 SH2B1 UBQLN4 EFCAB7 FN3KRP LSG1 LINC00910 CKAP5 PSMB3 MT-TR VPS25 AHCYL1 FTCD PPP1R8 DUS1L GPATCH4 ASCC1 ACLY HMGB3P22 PPP6R1 SRRT MRPL24 ARVCF MRPS33 THOC5 PPCDC RPL7L1 CYP2S1 RAI14 DHX8 GNG4 KPTN NMNAT1 CD2BP2 UIMC1 SNAP47 GINS3 NHSL1 NDUFS7 POLR2I YIPF2 AP4B1 SH3PXD2B TCHP DDX55 EIF3K MST1P2 GNAL ZNF286A AP2S1 INTS8 NME1-NME2 ZNF224 ZNF212 PRIM1 DBNL BANF1 ECH1 POLR3B DOHH PCBD2 SYBU GTPBP2 STAT6 CDK5RAP1 ABCF2 ZNF404 WDR4 MLLT6 ANK2 BMS1 N6AMT1 TRAPPC9 TRIP4 MAP3K9 ZFP14 SEC13 COPA MARK4 GTF3C5 SAMD4B TRAK1 CHD3 ZNF573 ACP1 RHOT2 TMEM101 PTPRF TBCB AURKAIP1 SNUPN ZNF131 BCL6 TCF3 C1orf159 ZNF793 ADRM1 MPG ZNF205 TP53 PDZD7 TRUB1 TIMM44 FIS1 LEMD2 BPNT1 SYNE2 PIGL FUT10 UBTF NDUFB7 MUC1 DNM1L TRUB2 THRB-AS1 LINC00888 SETD5 TIPRL ERLIN1 PHRF1 CLNS1A SLC33A1 APOBEC3B INO80B EIF2D ZNF740 HEXIM2 LASP1 ANO8 MRPS16 RFFL MAN2C1 ISYNA1 C12orf43 BAG2 NAT1 TRIM52 TMEM259 ADSL NOXA1 JAKMIP2 ZC3HC1 RBL1 FOXP2 ABHD2 SDHAF1 TNPO3 ATRIP NSL1 BAK1 TMPO SNHG17 LZTS2 COQ5 TSC22D4 CHD8 TLCD1 DCLRE1B TEFM ZNF425 MTR IGDCC4 C1orf194 C11orf65 RUFY1 SHB KIF6 MBD6 KLHL12 IL17RC MTF2 CDH24 SPRYD4 AFMID PSMD3 LYPLA2 SLC35B4 ZBTB41 CALM3 BNIP1 SENP2 IGF1R METTL17 DHPS WDR25 SLC44A1 PRKAB2 LINC00663 DSP SLC12A9 ZNF30 PFKL PDXDC1 COQ4 SMC4 IPO4 METTL9	up	*
MIR548AE_3P_MIR548AQ_3P	0.0026139	0.0262135	0.4317077	-0.1985495	-1.231291	684	EREG SIDT2 AKAP5 TRHDE SECISBP2L ZC3H12C RAB3C FYN CCL3L1 QKI GTF2I DYRK1A PRKAR1A VAPA TET2 ZBTB2 MOB1B ZEB2 ARHGAP29 CNST STARD4 MCTP1 HBEGF TM2D3 ADAM17 SPIRE1 TTYH2 CAMTA1 PAG1 SLC7A11 PEX5L PPP3CA TMEM41B ZEB1 PDE4D TCF7L2 CYP4V2 MCL1 ZNF365 ZYG11B FLI1 SLC7A2 EXOSC9 HMGN1 SORBS1 BNIP2 PPM1K LIN7C ZSWIM6 AGR3 ACSL3 PLEKHM3 ZFAND5 VASP TJP1 MED6 MAFG SOCS5 ZNF24 ATL3 IRAK2 PLEKHB2 RNF139 ZMPSTE24 ZNF706 KIAA0408 AFF1 BACE1 CNOT6L LIN7A STK24 USP25 SERTAD2 UFM1 RBPJ ARL6IP5 CREBRF ETF1 FMNL2 DCP1A CREM YBX1 PHACTR2 NEK7 TIGD3 APPL1 PPP6C UTRN PSMA1 ARL6IP6 CPEB4 KCTD12 ETS1 MED30 FOXN2 EPC1 FERMT2 FYTTD1 BAG5 FBXO11 SKIL TTC14 PIK3R1 UBAC2 PCGF5 CREB1 RC3H1 LPCAT2 GTDC1 FAM177A1 THSD7B YWHAZ RGS13 ZNF20 CELF2 FOS PELI1 AGPS CDK17 YTHDF3 PKD2 NAPG MAPK8 BTBD7 ING3 MME AZIN1 DCK SERPINB1 PDS5B ABHD13 NAB1 AOX1 CNOT7 MAP3K2 TLDC2 ATXN1 GNB4 CRY1 SBSPON RIMKLB N4BP2L2 MICU3 SERINC3 MBNL1 INO80D GTF2B COMMD9 ARAP2 ITPRIPL2 BLOC1S2 CXCR4 VPS4B CYP2U1 ARL14EP UBE2D1 ZDHHC21 SSH2 SOAT1 KPNA4 RBMS3 SCAI PAK2 SKI CECR2 FAM126B MMD CAMSAP2 C21orf91 RORA NAA15 NABP1 SFPQ GSPT1 DNAJB5 EVI5 TRIM36 ZBTB44 ZNF326 MAP4 ABI1 EPG5 SUGT1 PSIP1	down	*
ZNF407_TARGET_GENES	0.0011713	0.0143870	0.4550599	0.2386077	1.230692	1547	CPS1 PRR15 FOXM1 FOXA3 DDX12P LAD1 DNAH2 LYSMD1 CECR7 RPGRIP1L S100A2 ZNF84 COIL IGF2BP3 C17orf75 HOXB6 GBAP1 PDCD2L PSPH PBK SLC2A1 NUDCD3 TSFM DEPDC1 FANK1 MRPL46 METTL1 CCDC74A GINS1 EFNA3 CDK4 RACGAP1 ANKZF1 CABIN1 LRRC37A3 DBF4B NAALADL2 EIF2B5 FLAD1 AP1S1 NUF2 CENPA GPI TMEM254-AS1 CDC6 STC2 GOLGB1 KNOP1 HOXB7 LSR XPNPEP1 EIF3B DTL CCT6A MCM8 PIP4K2C MIS18A KIF27 B4GALT4 MRPS35 CDK5RAP3 LRRC27 COX11 SPDL1 SYT12 NME1 MANSC1 WDR62 ASAH2B ITGA2 POLR3A BZW2 CCDC150 C1orf220 NDUFB8 EXO1 CISD1 STRA6 CHAF1A BBS1 RPAP1 ZFYVE27 C9orf116 CUL9 QTRT1 KNTC1 RHNO1 TSGA10 CCDC13 CCT5 CENPL EME1 NUP155 WDR3 VANGL1 C20orf96 SAE1 ATR TPR KLHL25 SMARCAL1 COASY RGL1 SETDB1 ZNHIT6 PKM ENTPD6 MRPL27 PASK BLOC1S1 ZNF226 CDC25C ANG NME5 PPP1R35 MORC2 ZNHIT1 CHEK1 GET4 THYN1 MAD2L1 KIF3C PFKP ABCB9 TIMM50 KCNJ11 MRPS11 BRIP1 OGFOD2 IPO9 FNTB REPIN1 LRRIQ1 COMMD4 FADS2 SYMPK RNASEH2B-AS1 C2CD3 FBXO16 ARL16 ALDOA NIPAL1 STXBP4 MGAT4B SRRM5 TULP3 CNPY2 DYRK2 PSRC1 FGGY CKS1B FAHD2A SUPT5H URI1 LRRC6 PABPN1 HDGF CDK12 DIDO1 MDH1B FAM135A ARPC1A PICK1 CCT3 PLCH1 XRRA1 KIAA0753 PHF12 RAPGEFL1 GOLGA8A DIS3L2 POC5 PGBD2 PSMB5 MRPS2 MRPL17 PMEL DHX33 TRIM41 ENPP3 ZNF789 KRBA1 FEN1 POLR1C ZNF775 TMEM79 TNPO2 TTC23L LINC00649 THAP8 USP42 PLCG1 TRAF5 MTBP ATAD3A PBLD UCKL1 TMEM231 RTCB C9orf43 FGFR1OP PA2G4 EIF6 RANGAP1 CHCHD3 TPD52L2 EFTUD2 ELMOD3 G6PC3 CEP63 UBFD1 CAPS2 INTS7 ILF2 BBS5 CCDC142 NPHP1 DPP3 EXOC7 GNPAT SATB2 SMG5 C19orf47 FAH COA3 DHX40 PSMA5 PUS1 ZNF133 SNRPA AARSD1 RAD9A UROS YIPF3 GALNS CCDC151 PLEKHG3 COG7 KIF22 RAD51D SUDS3 DUSP12 UBE2Q1 PPOX DTYMK C1orf131 NFATC4 AKAP8L SOX2-OT OS9 GEMIN5 ACAD10 LAMTOR2 SPA17 ZSWIM1 PRMT7 SLC4A2 DNMBP SYNGAP1 C12orf73 CCDC159 POLB ATAD5 PPME1 COPS6 DNAJB13 NAT9 NIF3L1 SLX4IP RAD50 SASS6 CLDN12 EPN1 TADA3 EP400 UBQLN4 SUPT16H FN3KRP TIMM13 L3MBTL2 PWWP2A CDC20 TMEM106B AHCYL1 NPRL3 AAAS FBXO22 POP7 FAHD1 ZNF76 PPP6R1 POLR2J FITM2 NOL6 SRRT ABCA7 CDK5RAP2 ODF2L ZNF320 MGME1 MRPS33 ANKIB1 C16orf58 GID8 METTL2B WDR83 RPL7L1 RAI14 LPCAT4 CENPT ZSWIM8 NSUN6 PIGU KPTN HEATR1 DDX23 DYNC2H1 FAM161A LANCL2 CLUH SLC35A3 SCYL3 SRSF1 HAX1 RAB3D ZNF599 LRCH4 EFHB ZBTB9 PIP5K1A NEURL4 POLR2I POLR3E RHOBTB1 HAUS4 TMEM254 AP4B1 SMARCC2 LRRC46 SF3A2 STK35 TCHP CEP152 MST1P2 DUS2 KLHL7 NUP62 LRRC14 ZNF580 NME1-NME2 B9D1 LHX4 MCRS1 RPS26 MAP3K14 TSC2 ULK4 NTMT1 PRR11 TMC5 GABPB1-AS1 GTF3C2 DDX54 SCNM1 RNF121 DOHH USP39 TTC31 PRPF31 CLUAP1 VPS33B INO80E HOOK2 PRSS22 RAD51 TRAPPC9 CAPN10 STK25 ZNF384 MTIF3 ZNF292 RNF123 FBXW11 ST20 COPA ARHGAP11A MLLT1 RPRD2 FAM118B SNX8 AGBL5 PTPRF TBCB UBAP2L ALKBH6 UQCRQ OSGEP SMC2 BCL6 MAPK8IP3 CENPE EIF4G1 ZNF793 ANKMY2 EARS2 MPG ALG1 GGCX PRPF3 HGS CHERP TSNARE1 APEX1 MRPS27 SLC36A1 SNRPC TTC30B SIAE FAM78B CDKAL1 NELFA SFXN5 RAD1 SPATA20 PI4KB NAT10 RABL6 PIAS4 CLASP1 TRUB2 ILVBL LINC00888 ATG4B PTPN13 COL16A1 ACAD8 DDX41 BRIX1 TRPC4AP C12orf10	up	*
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP	0.0043449	0.0385266	0.4070179	-0.1929694	-1.219971	798	RAB11FIP1 LPIN2 SLC12A6 TMEM52B OSBPL11 SECISBP2L CD55 CPEB2 C18orf32 RAPGEF2 PTPRE LRRFIP1 TTC7B ARRDC4 FIG4 TMEM170B FYN LPL INPP5K WDR74 GFOD1 SEC22C GPCPD1 PLEKHA1 YPEL5 MEF2A BCL2A1 IL1RN EPB41L3 TRIB1 ZEB2 TXNIP NUMB EDEM1 KIAA0355 SH2B3 NCEH1 B3GNT5 HBEGF SLC36A4 CHMP1B EIF1 CLEC7A EIF5 CSGALNACT2 KLF10 PAG1 SLC7A11 ADRB1 RBM4 SLC25A37 TFEC PDE4D CD37 TAPT1 AGO4 ARRB1 MTMR6 ITPRIP SGTB EPOR BST1 ZSWIM6 KLF4 ZCCHC24 ITM2B KLF9 UHRF1BP1L PARVB MAP1LC3B MYO1B CLIC4 SCAF4 ABCC4 CCL3 SSH1 RIT1 CDKN1A ST7L NR1D2 UBE2E2 PTPRC ATF3 CTBS RECK ARHGAP9 FCER1G ALOX5AP PLEK ARL4A NUTM2A-AS1 HTT N4BP1 TBC1D4 MAFF MIR17HG ANXA3 IKZF5 LIN7A HCK LACC1 BTG1 ZNF330 RBM39 TFAP2E FMNL2 TRAF3IP2-AS1 CTSS PHACTR2 PGD PNO1 RAB8B UTRN HCST SEC14L1 HECA CD48 CPEB4 USO1 ETS1 TYROBP CCDC50 CSTA JAK1 PPP1R15A PTGER4 SKIL IFRD1 GLIPR1 PNPLA8 HSPA13 MBNL2 ATL2 SERPINB6 ENTPD4 FSD1L HOMER1 SUCNR1 OGFRL1 TNFRSF10B APH1B GAS6-AS1 RNF146 ACSL1 SLC3A2 SLC25A24 AGPS CDK17 PXN-AS1 AZI2 USP7 PKD2 MYL12A TTBK2 CR1 FAM204A TCF4 DCAF5 SMCR8 SERPINB1 TGIF1 BAZ2B VAMP4 FPR2 SH3RF3 DUSP5 CNOT7 ATXN1 HBP1 GPR84 TAGAP GABARAPL1 PHF11 RGS2 VPS39 KAT2B MR1 KTI12 ATAD2B HACE1 RNF2 BMP2K ARAP2 BNIP3L IL18 NEK1 IL18RAP CCDC69 ZNF438 SEMA4A ALDH6A1 SP100 DDX59 METTL7A PCBP1-AS1 NHLRC3 STK4 C7orf31 CCDC92 RET RAB2B FOXJ2 DNAJB9 KIF1B NAA15 GRB10 NABP1 GSPT1 WDFY3 NUP160 MIER3 ARFGAP3 TNFRSF10D PMAIP1 ACAT1 LYZ MED17	down	*
GO_REGULATION_OF_SECRETION	0.0052259	0.0441925	0.4070179	-0.1989712	-1.216192	599	SLC6A4 FFAR4 RBP4 RAB11FIP1 KMO SIDT2 IL17RB IL1A FOXF1 HMOX1 FCN1 EDNRB ADTRP KCNA2 GATA2 IL1B P2RY1 PLA2G10 RAB3C LPL HCAR2 STXBP6 PRAM1 VAMP2 HMGCR FGF10 IL1RL1 GAS6 LAMP1 CYP4A11 CD22 FGR ANXA1 MIR146A CARD16 MCTP1 ADA CD33 CACNA2D2 FOXA2 RAPGEF4 RAP1A RAB33B ANXA5 ABCG1 FOXP1 GATA3 PPP3CA RGCC TRAF6 SFRP1 SPTBN1 CRTAM SRGN TCF7L2 CD58 IL10 ARRB1 RAB12 SDCBP CASP1 TACR2 ACSL3 PTAFR REST ARNTL KLF7 MYRIP CCL3 DPH3 PER2 CADM1 P2RY2 TLR4 MIR24-2 FRMD4A PTGER3 FCER1G INHBA CPT1A CLEC9A PINK1 GNAI2 BACE1 CPLX1 TGFB2 KCNA5 VAMP3 IL6 CD160 SGK1 RAB8B PDCD6IP NOTCH1 GLUD1 ADRA1A RAC2 CARD8 IFNGR1 PTGER4 CCR7 PRKCE CREB1 OSM RAB8A NPR1 UNC13B RALB CD34 MBP PRKCG CD74 CHIA STXBP3 TGFB1 PARD6A AP1G1 SERPINB1 NLRP6 LRRC32 APBB1 PIK3C3 IRS2 EXOC1 ORM2 CLASP2 CRY1	down	*
GO_CHEMICAL_HOMEOSTASIS	0.0016019	0.0181059	0.4550599	-0.1934413	-1.212803	904	SLC24A4 RBP4 EPAS1 HCRTR1 GPR17 SLC31A2 RAMP3 SIDT2 CD52 HMOX1 SWAP70 ABHD5 SLC12A6 MCOLN1 EDNRB PPARG GPIHBP1 CD55 GATA2 SFRP4 FABP4 F2RL3 SNX10 ADCY9 P2RY1 GPR65 ADCY4 PLA2G10 CDH5 INSIG1 KL PCSK9 TRPC3 FYN LPL JPH4 CCRL2 INPP5K CAV1 NEDD4L AQP9 CRY2 ADRA1D GTF2I SLC39A8 ADCYAP1R1 TBXA2R C5AR1 S1PR1 HMGCR PRKAR1A MIR27B GAS6 ACSM1 CYP4A11 SLC11A1 TLCD2 SCN5A ACOXL CD36 JPH2 TMPRSS6 MIR146A ATP2B1 TRA2B FOXA2 KCNK3 RAP1A ABCG2 PICALM ANXA5 ABCG1 GLS MALL SLC7A11 MS4A1 ADIPOR1 CLN5 PPP3CA SLC25A37 GRN PDE4D TCF7L2 TFRC ATP6V1H TMEM38B ATP6V1B2 FBXL5 GPR4 CYBRD1 FABP5 ARRB1 SYNPO PTGIR PPT1 FOXO1 KCNMA1 SLC12A4 SLC7A8 CEBPA ATP6V1D MAFG KLF7 RMDN3 CLIC4 CCL3 P2RY2 NR1D2 PTPRC AQP4 ATP6V0D2 PTGER3 SFTPD SMAD7 ADIPOR2 RAP1GDS1 WFS1 HTT GPR157 UBASH3B CYP26B1 NUS1 GNAI2 CALM2 PLCD1 PTH1R HEXB SRF PRCP KCNA5 PDK4 MYLIP S1PR4 SLC8A1 ADCY2 PDE6A PSEN1 PDE6B AQP3 SLC9B1 CNNM2 HK3 ADRA1A JPH1 ATP6V0B GSTO1 PTGER4 CCR7 PIK3R1 ACKR3 PRKCE PTGER2 NPR1 GRIA1 UNC13B ATP13A3 PRKACA SLC10A7 HOMER1 SUCNR1 CLN3 FGFR4 PLCG2 ATP6V0D1 PNPLA2 CALM1 FOXO3 PKD2 SLC4A5 SYPL2 PNPLA3 CCR4 SPOP STXBP3 EPB42 EHD1 FPR2 ATP6V1A MCUR1 IRS2 SLC24A1 ATP6V0C SLC8A3 SOD2 CCR1 SCARA5 NPTN CRY1 GNA13 GPR18 CALB1 TSPO COMMD9 CCR6 ICAM1 FGF2 IL18 SLC34A2 ABL2 FKBP1A SLC31A1 VGF SCN7A ELOVL1 RTN4 SLC24A5 TPT1 TIAM1 CXCR4 CYB5R4 ORMDL1 CCR9 PTCH1 MT1M GPD1L SOAT1 ISCU BOK MBD5 CD19 SREBF2	down	*

REACTOME Pathways

pathway	pval	padj	log2err	ES	NES	size	leadingEdge	state	pvlabel
NGF-stimulated transcription	0.0000016	0.0002104	0.6435518	-0.6197616	-2.448257	34	4066 1959 8061 10221 5978 3399 3398 23237 6722 3400 6446 3726 1385 2353 2354 4664 3727 7425 1958 1386 2033 4209	down	***
Nuclear Events (kinase and transcription factor activation)	0.0000001	0.0000233	0.6901325	-0.5608702	-2.420244	54	4066 1959 8061 4205 10221 1845 5978 3399 3398 23237 6722 6196 3400 5515 6446 3726 1385 6195 2353 2354 5516 4664 3727 7425 1849 1958 1848 1386 5594 2033 4209 5598	down	***
Activation of the pre-replicative complex	0.0000012	0.0001767	0.6435518	0.6713067	2.230247	31	8318 55388 5558 5426 990 4173 4171 4998 84515 81620 23649 4176 4172 23594 5427 51053 8317 6117 4175 4174 5557	up	***
DNA strand elongation	0.0000020	0.0002437	0.6272567	0.6734992	2.216090	30	8318 5558 9837 4173 4171 84515 84296 23649 5425 4176 4172 3978 1763 2237 51659 5424 6117 4175 4174 64785 5557 5985	up	***
DAP12 interactions	0.0000413	0.0022980	0.5573322	-0.5586049	-2.206669	34	10326 2534 342510 3824 124599 7305 54210 5295 2885 284266 5336 3822 100049587 10451 100528032 27040 22914	down	**
Interleukin-3, Interleukin-5 and GM-CSF signaling	0.0000292	0.0017554	0.5756103	-0.5374893	-2.177928	40	2534 867 1398 6776 3055 3560 3716 2889 5295 2885 5566 7534 7314 7006 1437 1439 3567 8503 7316 3717 6850 7311 5290 5781 4067	down	**
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	0.0000106	0.0008404	0.5933255	0.8147625	2.150340	12	727897 56667 56913 4585 94025 4586 200958 4588	up	***
Unwinding of DNA	0.0000287	0.0017554	0.5756103	0.8007544	2.113370	12	8318 9837 4173 4171 84515 84296 4176 4172 51659 4175 4174 64785	up	**
Activation of ATR in response to replication stress	0.0000147	0.0010640	0.5933255	0.6120263	2.112039	36	8318 55388 990 4173 4171 993 4998 84515 545 4176 63967 4172 995 1111 23594 5883 8317 6117 4175 4174	up	**
Signaling by BMP	0.0005440	0.0150239	0.4772708	-0.5939694	-2.084699	23	4091 94 64388 650 659 9765 7323 4092	down	*
Leishmania infection	0.0000000	0.0000011	0.7749390	-0.3867735	-2.084627	187	10268 3552 2838 3553 3973 115 196883 10266 2534 10458 10203 117 5573 9844 998 59350 2268 10628 64174 6868 953 2793 153 2788 154 1398 151306 7295 3586 5739 4210 834 4790 10096 10810 2771 805 5745 10097 3055 3071 4641 108 3569 10163 3725 5734 2885 1385 5732 5566 5336 801 5599 10451 2770 2787 53831 59345 3606 10109 3362 114548 60 135 917 10092	down	***
FOXO-mediated transcription	0.0000295	0.0017554	0.5756103	-0.4849278	-2.084101	53	4287 847 857 10370 2908 10628 91584 10000 7295 2308 9314 1026 65018 694 7534 2309 4802 6648 8850 4087 5934 1387 25942 4089 1027 7529 2033 23411 4801	down	**
DNA Double-Strand Break Repair	0.0000000	0.0000084	0.7337620	0.4875448	2.081082	120	2138 11200 2139 8914 10721 672 5426 5932 7516 3980 9156 7158 27434 83695 146956 545 5425 63967 5591 197342 11073 1111 10635 7515 83990 641 5536 142 5427 1763 2237 64421 27343 5883 5892 5424 84464 10111 79728 6117 7336 23030 7518 55775 51720 890 51750 5985 5888 2070 22976 51548 7157 5810 51588 10038 80198 23514 7156 84126 9025 8924 80010 7520 54962 5531 10714 2547 116028 5890 5983 580 56655 5984	up	***
Defective GALNT12 causes colorectal cancer 1 (CRCS1)	0.0000543	0.0028002	0.5573322	0.7883316	2.080583	12	727897 56667 4585 94025 4586 200958 4588	up	**
RUNX3 regulates NOTCH signaling	0.0007517	0.0198172	0.4772708	-0.7177561	-2.071748	12	3280 3516 84441 4851 864 8850 1387 22938 2033	down	*
Cell-extracellular matrix interactions	0.0002797	0.0104659	0.4984931	-0.6642751	-2.061262	16	55679 3987 29780 7408 10979 2318 60 55742 6251 3688	down	*
DNA Replication	0.0000001	0.0000239	0.6901325	0.4829435	2.055329	118	8318 55388 5558 9837 5426 990 1871 4173 4171 4998 84515 84296 81620 23649 5425 4176 1870 4172 3978 23594 5710 6502 51433 5427 51053 1869 5693 1763 51434 2237 5704 898 8697 5686 5721 51659 51343 64682 5424 5708 8317 5691 6117 4175 4174 64785 5692 890 5557 29882 5985	up	***
Incretin synthesis, secretion, and inactivation	0.0010744	0.0256970	0.4550599	-0.7316677	-2.052441	11	338557 60559 6934	down	*
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	0.0010744	0.0256970	0.4550599	-0.7316677	-2.052441	11	338557 60559 6934	down	*
Kinesins	0.0000090	0.0008389	0.5933255	0.5611238	2.050957	50	547 113220 147700 10112 146909 347733 29127 55582 9493 56992 9371 11004 3832 3797 3798 124602 3796 7280 113457 3835 51807 55605 9585 64837 89953 23046	up	***
Scavenging of heme from plasma	0.0000759	0.0036678	0.5384341	0.8138614	2.046920	10	3240 3039 3040 3043 8542 3250	up	**
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes	0.0007986	0.0205868	0.4772708	-0.6165916	-2.046689	19	4287 847 2908 91584 2308 2309 6648 4087 25942 4089	down	*
Homology Directed Repair	0.0000014	0.0001965	0.6435518	0.4944146	2.040039	94	8914 10721 672 5426 5932 7516 3980 9156 7158 83695 146956 545 5425 63967 197342 11073 1111 10635 7515 83990 641 142 5427 1763 2237 5883 5892 5424 84464 10111 79728 6117 7336 51720 890 51750 5985 5888 51548 5810 51588 10038 80198 23514 7156 84126 9025 8924 80010 54962 5531 10714 116028 5890 5983 580 56655 5984	up	***
IRAK4 deficiency (TLR2/4)	0.0012547	0.0291094	0.4550599	-0.7449376	-2.011658	10	4615 948 23643 7099	down	*
Regulation of signaling by CBL	0.0009638	0.0237874	0.4772708	-0.6038025	-2.011130	20	2534 867 1398 3055 2889 5295 2885 7314	down	*
COPI-dependent Golgi-to-ER retrograde traffic	0.0000079	0.0007653	0.5933255	0.4859750	1.986880	88	547 113220 147700 10112 146909 347733 29127 9276 55582 9493 56992 26958 22820 9371 11004 3832 11014 3797 23423 4905 3798 53407 124602 3796 7280 113457 3835 381 51807 55605 9585 64837 89953 11015 8729 23046 22818 55738 1314 54732 1062 51226 84790	up	***
O-linked glycosylation of mucins	0.0000303	0.0017584	0.5756103	0.5394786	1.980125	51	727897 56667 56913 79623 11226 4585 9245 94025 10164 4586 8693 55568 200958 4588 50614 146712 10331	up	**
GPVI-mediated activation cascade	0.0004547	0.0136997	0.4984931	-0.5195596	-1.980105	31	51266 2534 998 387 388 2207 23533 5880 391 5295 5336 10451 27040 5294 10630 8503 146850 6850 5590 5290 5781 3937 4067	down	*
DNA Replication Pre-Initiation	0.0000201	0.0013746	0.5756103	0.4936440	1.979938	77	8318 55388 5558 5426 990 1871 4173 4171 4998 84515 81620 23649 4176 1870 4172 23594 5710 5427 51053 1869 5693 5704 5686 5721 5708 8317 5691 6117 4175 4174 5692 5557	up	**
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)	0.0003139	0.0105559	0.4984931	0.7495259	1.978166	12	727897 56667 4585 94025 4586 200958 4588	up	*
Regulation of FOXO transcriptional activity by acetylation	0.0015836	0.0346593	0.4550599	-0.7510699	-1.957840	9	10628 7295 2308 2309 8850 1387 2033 23411	down	*
Platelet activation, signaling and aggregation	0.0000000	0.0000118	0.7195128	-0.3519679	-1.955483	220	51266 5175 7123 9002 5028 7222 2534 22915 1521 6915 998 928 2621 387 948 11069 5906 2793 308 57406 2788 1398 5552 5154 388 1675 408 8526 7057 4352 10257 6403 2207 5341 2776 23533 2771 805 7450 7042 9749 51706 5880 391 5295 5581 2885 10487 7534 8407 5336 801 5582 1608 747 6814 7040 10451 54495 55664 2770 2787 59345 334 5005 10672 88 27040 9948 409	down	***
Cell Cycle Checkpoints	0.0000000	0.0000013	0.7749390	0.4264846	1.953819	233	8318 55388 11200 701 57122 891 1063 10403 672 51512 5347 83540 55143 9212 1058 990 9133 5932 4173 4171 993 4998 1780 84515 11130 54908 9156 7158 9735 83695 699 91687 545 11004 4176 8379 63967 4172 995 11073 1111 23594 4085 5710 79172 4193 147841 9088 83990 641 3619 51433 983 64946 332 5693 1763 3796 51434 140735 5704 401541 5905 898 8697 5686 5883 5721 55166 64682 5708 79902 8317 10111 64105 9793 5691 991 79019 6117 7336 4175 1783 80152 4174 51720	up	***
MyD88 deficiency (TLR2/4)	0.0018693	0.0394258	0.4550599	-0.7456311	-1.943662	9	4615 948 23643 7099	down	*
Interleukin-1 processing	0.0014906	0.0329362	0.4550599	-0.7929283	-1.941123	7	3552 3553 834 4790 3606	down	*
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)	0.0000210	0.0013938	0.5756103	0.4742627	1.938995	88	8914 672 5426 5932 7516 9156 7158 83695 146956 545 5425 63967 197342 11073 1111 10635 83990 641 5427 1763 5883 5892 5424 84464 10111 79728 6117 7336 51720 890 51750 5985 5888 51548 5810 51588 80198 23514 7156 84126 9025 8924 80010 54962 5531 10714 116028 5890 5983 580 56655 5984	up	**
Anti-inflammatory response favouring Leishmania parasite infection	0.0000109	0.0008404	0.5933255	-0.3874641	-1.920624	111	10268 2838 3973 115 196883 10266 2534 10203 117 5573 59350 2268 64174 6868 2793 153 2788 154 151306 3586 5739 2771 805 5745 3055 108 3569 5734 1385 5732 5566 5336 801 2770 2787 53831 59345	down	***
Leishmania parasite growth and survival	0.0000109	0.0008404	0.5933255	-0.3874641	-1.920624	111	10268 2838 3973 115 196883 10266 2534 10203 117 5573 59350 2268 64174 6868 2793 153 2788 154 151306 3586 5739 2771 805 5745 3055 108 3569 5734 1385 5732 5566 5336 801 2770 2787 53831 59345	down	***
NOTCH4 Intracellular Domain Regulates Transcription	0.0012983	0.0298216	0.4550599	-0.6174060	-1.915825	16	3280 3516 84441 4851 8850 1387 2324 22938 23462 2033	down	*
G2/M Checkpoints	0.0000051	0.0005602	0.6105269	0.4485142	1.914870	121	8318 55388 11200 891 672 51512 990 9133 5932 4173 4171 993 4998 84515 9156 7158 83695 545 4176 63967 4172 995 11073 1111 23594 5710 9088 83990 641 983 5693 1763 5704 5686 5883 5721 5708 8317 10111 5691 6117 7336 4175 4174 51720	up	***
Synthesis of DNA	0.0000098	0.0008404	0.5933255	0.4523195	1.909196	111	8318 5558 9837 5426 990 4173 4171 4998 84515 84296 81620 23649 5425 4176 4172 3978 23594 5710 6502 51433 5427 5693 1763 51434 2237 5704 898 8697 5686 5721 51659 51343 64682 5424 5708 5691 6117 4175 4174 64785 5692 890 5557 29882 5985	up	***
Cell recruitment (pro-inflammatory response)	0.0025176	0.0486730	0.4317077	-0.5439429	-1.909117	23	3552 3553 10628 953 7295 4210 834 4790	down	*
Purinergic signaling in leishmaniasis infection	0.0025176	0.0486730	0.4317077	-0.5439429	-1.909117	23	3552 3553 10628 953 7295 4210 834 4790	down	*
Cell surface interactions at the vascular wall	0.0000142	0.0010628	0.5933255	-0.3878778	-1.906771	105	51378 7010 4973 5175 6693 7056 2534 960 857 90952 2621 9056 3678 23657 83700 140885 965 23428 3687 6402 6403 58494 2207 10544 962 54210 5295 2995 2885 8795 6520 972 7040 29802 9046	down	**
Resolution of Abasic Sites (AP sites)	0.0003361	0.0111408	0.4984931	0.5473330	1.894898	37	5426 3980 23583 670 5425 3978 7515 142 5427 7374 2237 8930 5424 5423 6117 5985 11284 8505 4350 79661 328 10038	up	*
Type I hemidesmosome assembly	0.0004769	0.0141833	0.4984931	0.7838400	1.894130	9	1308 3852 3918 3691	up	*
ADORA2B mediated anti-inflammatory cytokines production	0.0000416	0.0022980	0.5573322	-0.4061710	-1.893223	79	10268 2838 3973 115 196883 10266 10203 117 5573 59350 2793 153 2788 154 151306 5739 2771 5745 108 3569 5734 1385 5732 5566 2770 2787 53831 59345	down	**
Synthesis, secretion, and deacylation of Ghrelin	0.0022785	0.0459667	0.4317077	-0.6174089	-1.892416	15	60559 7941 9314 590	down	*
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	0.0000540	0.0028002	0.5573322	-0.3906520	-1.883830	93	114132 146722 126014 342510 911 933 29992 925 946 945 3903 56253 374383 6402 6441 10871 3824 124599 926 11126 3820 10870 7305 54210 947 6614 3384 912 975 100528032 9976 3383 3385 930 27180 917 22914 51348 340205 3683 3688 54209 89790 2214 916	down	**
Chromosome Maintenance	0.0001102	0.0049158	0.5384341	0.4695952	1.883482	77	55355 8607 5558 80119 1058 54069 10856 91687 23649 5425 387103 3978 79172 79075 641 64946 1763 2237 401541 5437 63922 55166 5424 64105 79019 6117 5439 54921 80152 5438 890 5557 51750 5985	up	**
Deposition of new CENPA-containing nucleosomes at the centromere	0.0005325	0.0148846	0.4772708	0.6152997	1.879066	22	55355 8607 1058 54069 91687 387103 79172 64946 401541 55166 64105 79019 80152	up	*
Nucleosome assembly	0.0005325	0.0148846	0.4772708	0.6152997	1.879066	22	55355 8607 1058 54069 91687 387103 79172 64946 401541 55166 64105 79019 80152	up	*
Cell Cycle	0.0000000	0.0000000	0.9325952	0.3830628	1.869009	560	2305 55722 10112 55355 8607 8318 55388 11200 701 57122 4751 891 1063 84057 10403 5558 80119 672 347733 9837 1019 51512 5426 80321 5347 83540 55143 9212 1058 9232 9700 990 22974 1871 7029 9133 5932 4173 5578 4171 7298 993 4605 4998 1780 84515 54069 84296 9918 11130 81620 10540 54908 23354 11190 10856 3161 8945 9156 9493 10734 7158 9735 83695 699 7153 91687 6790 9631 9985 4957 23649 10388 545 5425 9814 7175 11004 4176 8379 1870 387103 63967 6241 64900 113130 4172 4001 995 3978 11073 1111 23594 4085 5710 79172 4193 147841 208 79075 9088 83990 641 4331 6502 3619 1163 54892 1031 51433 983 5427 55835 11083 64946 332 51053 23353 1869 64151 5693 1763 3796 51434 2237 23165 140735 5704 401541 3837 5905 5437 653784 80097 80254 898 55125 8697 7283 5686 22981 5883 7280 5721 113457 7083 51807 63922 55166 3065 157570 51659 51343 55957 64682 5424 5708 79902 51400 8317 10111 64105 9793 5691 991 79019 27175 8086 6117 5439 92421 55755 7336 4175 54921 1783 80152 4174 51720 54801 64785 5438 1104 54930 5692 22995 23636 4438 7840 890 5557 8815 51750 29882 5985 27229 22897 23175 5888 55055 6396 23291 29922 27243 10592 23383 1062 7157 2801 221496 23224 994 11065 23310 84790 5528 23225 5810 51588 23332 9688 23397 80184 79643 1778 27030 55164 7156 10733 10142 5116 79980 984 5933 5529 26271 5699 51451 10844 5720 84126 25936 7112 55651 4869 9025 55920	up	***
Homologous DNA Pairing and Strand Exchange	0.0003036	0.0105559	0.4984931	0.5323833	1.867286	40	672 5932 7516 9156 83695 545 11073 1111 10635 83990 641 1763 5883 5892 10111 79728 6117 5985 5888 5810 7156 84126 80010 116028 5890 5983 580 5984	up	*
Resolution of Sister Chromatid Cohesion	0.0000193	0.0013600	0.5756103	0.4459382	1.866740	105	701 57122 891 1063 10403 347733 5347 83540 55143 9212 1058 9133 1780 11130 54908 9735 699 91687 11004 8379 113130 4085 79172 147841 3619 983 64946 332 3796 140735 401541 5905 7280 113457 51807 55166 79902 64105 9793 991 79019 1783 80152	up	**
CDC6 association with the ORC:origin complex	0.0007819	0.0203832	0.4772708	0.7248469	1.863354	11	990 1871 4998 84515 1870 23594 1869	up	*
HDR through Homologous Recombination (HRR)	0.0002010	0.0080912	0.5188481	0.4834186	1.850138	63	672 5426 5932 7516 9156 83695 146956 545 5425 197342 11073 1111 10635 83990 641 5427 1763 5883 5892 5424 84464 10111 79728 6117 51750 5985 5888 5810 80198 23514 7156 84126 80010 10714 116028 5890 5983 580 56655 5984	up	**
Resolution of D-Loop Structures	0.0007167	0.0191109	0.4772708	0.5558526	1.846680	31	672 5932 7516 9156 146956 197342 10635 83990 641 1763 5892 84464 10111 79728 51750 5888 80198 23514 7156 80010 116028 5890 580	up	*
Mitotic Prometaphase	0.0000035	0.0004026	0.6272567	0.4124242	1.843358	174	55722 701 57122 4751 891 1063 10403 347733 80321 5347 83540 55143 9212 1058 9133 1780 9918 11130 10540 54908 23354 11190 9735 699 91687 4957 9814 11004 8379 113130 4085 79172 147841 3619 983 55835 64946 332 64151 3796 140735 401541 5905 653784 80097 80254 55125 7283 22981 7280 113457 51807 55166 79902 64105 9793 991 79019 27175 55755 1783 80152 54801 54930 22995 7840 27229 22897 55055 6396 29922 10592 1062 84790 5528 23332 23397 80184 1778 10733 10142 5116 79980 5529 10844 25936	up	***
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal	0.0001078	0.0049032	0.5384341	0.4532102	1.826351	84	701 57122 1063 10403 5347 83540 55143 9212 1058 1780 11130 54908 9735 699 91687 11004 8379 4085 79172 147841 3619 64946 332 3796 140735 401541 5905 55166 79902 64105 9793 991 79019 1783 80152	up	**
Amplification of signal from the kinetochores	0.0001078	0.0049032	0.5384341	0.4532102	1.826351	84	701 57122 1063 10403 5347 83540 55143 9212 1058 1780 11130 54908 9735 699 91687 11004 8379 4085 79172 147841 3619 64946 332 3796 140735 401541 5905 55166 79902 64105 9793 991 79019 1783 80152	up	**
Mitochondrial translation elongation	0.0002407	0.0093057	0.5188481	0.4513524	1.818734	82	10102 26589 60488 29088 26284 11222 51264 64963 10884 64979 51253 51116 63875 6183 65993 65003 122704 51073 7818 118487 51649 79590 51650 10573 64975 116540 51258 64928 64432 128308 90480 65005 219927 54998 23107 55052 51642 64949 51021 6182 84545 51069 64968	up	**
Resolution of D-loop Structures through Holliday Junction Intermediates	0.0010554	0.0256970	0.4550599	0.5525845	1.818231	30	672 5932 7516 9156 146956 197342 10635 83990 641 1763 5892 84464 10111 79728 5888 80198 23514 7156 80010 116028 5890 580	up	*
Cell Cycle, Mitotic	0.0000000	0.0000004	0.8012156	0.3774405	1.817905	452	2305 55722 10112 8318 55388 701 57122 4751 891 1063 10403 5558 347733 9837 1019 51512 5426 80321 5347 83540 55143 9212 1058 9232 9700 990 22974 1871 7029 9133 4173 5578 4171 7298 993 4605 4998 1780 84515 84296 9918 11130 81620 10540 54908 23354 11190 3161 8945 9493 9735 699 7153 91687 6790 9631 4957 23649 5425 9814 7175 11004 4176 8379 1870 6241 64900 113130 4172 4001 995 3978 23594 4085 5710 79172 147841 208 9088 4331 6502 3619 1163 54892 1031 51433 983 5427 55835 64946 332 51053 1869 64151 5693 1763 3796 51434 2237 23165 140735 5704 401541 3837 5905 653784 80097 80254 898 55125 8697 7283 5686 22981 7280 5721 113457 7083 51807 55166 3065 157570 51659 51343 55957 64682 5424 5708 79902 51400 8317 64105 9793 5691 991 79019 27175 8086 6117 92421 55755 4175 1783 80152 4174 54801 64785 1104 54930 5692 22995 23636 7840 890 5557 8815 29882 5985 27229 22897 23175 55055 6396 23291 29922 27243 10592 23383 1062 7157 2801 221496 994 11065 23310 84790 5528 23225 23332 9688 23397 80184 79643 1778 10733 10142 5116 79980 984 5933 5529 26271 5699 51451 10844 5720 25936 7112	up	***
DNA Repair	0.0000003	0.0000481	0.6749629	0.3930744	1.817094	260	2138 8607 55215 11200 2139 8914 10721 29089 672 5426 5932 5395 7516 51514 3980 23583 9156 7158 27434 83695 2175 670 146956 545 5425 84164 63967 5591 2177 3978 197342 11073 1111 86 10635 7515 83990 56852 641 5536 2068 4331 142 353497 5427 7374 1763 55247 2237 10459 10401 5437 2189 64421 2188 27343 8930 5883 5892 64708 4255 6917 124739 5424 5423 10980 84464 10111 79728 51008 6117 5439 57697 7336 23030 7518 55775 51720 5438 10445 4436 890 4798 51750 5985 283899 5888 2070 22976 51548 11284 8505 7508 4350 7157 79661 328 5810 1643 51588 79913 2071 121642 10038 83444 80198 23514 7156 27339 84126 9025 64858 2956 9937 10973 25913 8924 80010 7520 54962 57654 5531 9246 10714 50813 9978 2547 116028 4437	up	***
Mitochondrial translation	0.0002023	0.0080912	0.5188481	0.4439874	1.815216	88	10102 26589 60488 29088 26284 11222 51264 64963 10884 64979 51253 51116 63875 6183 65993 65003 122704 51073 7818 84340 118487 51649 79590 51650 10573 64975 116540 51258 64928 64432 128308 90480 219402 65005 219927 54998 23107 55052 51642 64949 51021 6182 84545 51069 64968	up	**
Presynaptic phase of homologous DNA pairing and strand exchange	0.0009534	0.0237844	0.4772708	0.5240904	1.814431	37	672 5932 7516 9156 83695 545 11073 1111 83990 641 1763 5883 5892 10111 6117 5985 5888 5810 7156 84126 80010 116028 5890 5983 580 5984	up	*
G1/S-Specific Transcription	0.0013880	0.0312627	0.4550599	0.5704016	1.813866	26	8318 990 7029 7298 4998 81620 6241 983 1869 898 7083 3065 55957	up	*
Cilium Assembly	0.0000067	0.0006769	0.6105269	0.4060572	1.807137	171	55722 84902 23322 4751 117177 54903 347733 55764 79989 80321 5347 11020 11336 10576 10540 23354 11190 582 9371 85302 60412 22948 4957 9814 112752 26160 3797 1258 26005 9657 983 79598 55835 7203 79867 140735 6608 51098 80254 129880 55125 4867 23265 7283 22981 7280 113457 51807 1262 26146 9793 8729 79600 55755 57539 54801 79659 54930 84747 22995 27077 7840 22897 23059 57787 200132	up	***
Processing of DNA double-strand break ends	0.0005133	0.0148632	0.4772708	0.4817155	1.805888	56	8914 672 5932 9156 7158 83695 545 63967 11073 1111 83990 641 1763 5883 10111 6117 7336 51720 890 5985 51548 5810 51588 7156 84126 9025 8924 80010 54962 5531 116028 5983 580 5984	up	*
Signaling by NTRK1 (TRKA)	0.0000621	0.0031344	0.5384341	-0.3660513	-1.804976	104	4066 1959 8061 117 4205 10221 387 5906 1398 1845 5978 3399 6016 3398 23237 6722 6196 3400 5515 6446 3726 2889 5295 2885 1385 6195 5899 2353 2354 5516 4664 8660 3727 7425 135 1849 1958 1848 1386 5594 7529 57498 2033 4209	down	**
Golgi-to-ER retrograde transport	0.0000543	0.0028002	0.5573322	0.4220209	1.801760	121	547 113220 147700 10112 146909 347733 29127 1780 9276 55582 10540 9493 636 56992 26958 22820 5050 9371 11004 3832 11014 3797 23423 4905 3798 53407 124602 3796 140735 51560 7280 113457 3835 381 51807 55605 9585 64837 89953 11015 8729 1783 23046	up	**
Ca2+ pathway	0.0005048	0.0148252	0.4772708	-0.4095939	-1.797206	57	5593 2793 51701 8322 5530 2788 6934 192670 192669 805 5145 5158 801 7481 2787 5534 59345 83439 5592 2791 7474 5148 5330 3709 27161 4772 54331 57690	down	*
FCGR3A-mediated phagocytosis	0.0003127	0.0105559	0.4984931	-0.4131094	-1.796415	55	2534 10458 9844 998 2268 1398 10096 10810 10097 3055 3071 4641 10163 2885 10451 10109 60 917 10092 10006 5594	down	*
Leishmania phagocytosis	0.0003127	0.0105559	0.4984931	-0.4131094	-1.796415	55	2534 10458 9844 998 2268 1398 10096 10810 10097 3055 3071 4641 10163 2885 10451 10109 60 917 10092 10006 5594	down	*
Parasite infection	0.0003127	0.0105559	0.4984931	-0.4131094	-1.796415	55	2534 10458 9844 998 2268 1398 10096 10810 10097 3055 3071 4641 10163 2885 10451 10109 60 917 10092 10006 5594	down	*
Neutrophil degranulation	0.0000000	0.0000009	0.7881868	-0.3051355	-1.792171	394	10326 6590 2219 4973 5175 84329 1604 4332 4048 847 401258 160364 5787 126014 960 1118 1727 5049 728 51646 4126 9218 2517 3916 6556 2268 387 948 57153 5611 4125 945 411 427 5906 2760 290 5806 2040 3903 140885 22918 2896 8649 51552 965 1471 2171 1675 6386 683 5724 5329 6093 2548 26578 51382 1509 10533 64114 23071 4790 23406 3687 5788 6402 10855 64333 963 2207 25801 8560 54918 10097 2720 3074 138050 5870 3071 5547 1520 5663 8773 10493 11031 3101 1522 7305 3304 23250 391 22875 11010 9535 5269 10487 5718 221 51411 1378 4311 7077 100049587 79930 1992 2358 81619 51143 527 53831 3958 5005 25798 80301 102 9798 29099 201294 3320 3312 25840 387921 27180 1075 10092 9342 5023 9861 8826 8804 1265 196527 4069 1535 535 1512 55754 23200 5594 3683 2512 6279 326624 2357	down	***
Mitochondrial translation termination	0.0003723	0.0121656	0.4984931	0.4440230	1.789200	82	26589 60488 29088 26284 11222 51264 64963 10884 64979 51253 51116 63875 6183 65993 65003 122704 51073 7818 84340 118487 51649 79590 51650 10573 64975 116540 51258 64928 64432 128308 90480 65005 219927 54998 23107 55052 51642 64949 51021 6182 84545 51069 64968	up	*
Mitochondrial translation initiation	0.0003840	0.0123744	0.4984931	0.4436492	1.787693	82	26589 60488 29088 26284 11222 51264 64963 10884 64979 51253 51116 63875 6183 65993 65003 122704 51073 7818 118487 51649 79590 51650 10573 64975 116540 51258 64928 64432 128308 90480 219402 65005 219927 54998 23107 55052 51642 64949 51021 6182 84545 51069 64968	up	*
Extra-nuclear estrogen signaling	0.0009285	0.0234152	0.4772708	-0.3949211	-1.777386	67	2069 857 1839 2793 3315 858 2788 10000 255324 2771 805 6722 374 5295 1385 2353 801 2309 6801 2770 2787 59345 3320 340481 8877 1027 5594 2791	down	*
G alpha (s) signalling events	0.0000871	0.0041239	0.5384341	-0.3601903	-1.776075	104	10268 2838 3973 115 196883 10266 5153 10203 117 59350 5143 5138 2793 153 2788 154 151306 5144 408 5739 2869 5151 5140 2771 5745 108 5734 5732 2770 2787 53831 59345 340980 3362 409 135 5141 8622 392392	down	**
Anchoring of the basal body to the plasma membrane	0.0003070	0.0105559	0.4984931	0.4360668	1.771618	86	55722 84902 23322 4751 117177 54903 80321 5347 10540 23354 11190 85302 4957 9814 26005 9657 983 79598 55835 79867 80254 55125 4867 7283 22981 9793 79600 55755 54801 54930 22995 27077 7840 22897 57787 23332 347240 80184 1778 10733 10142 5116	up	*
EML4 and NUDC in mitotic spindle formation	0.0001908	0.0079047	0.5188481	0.4261448	1.763344	100	701 57122 1063 10403 347733 5347 83540 55143 9212 1058 1780 11130 54908 9735 699 91687 11004 8379 4085 79172 147841 3619 64946 332 3796 140735 401541 5905 7280 113457 51807 55166 79902 64105 9793 991 79019 1783 80152	up	**
Mitotic Spindle Checkpoint	0.0003016	0.0105559	0.4984931	0.4249082	1.761341	101	701 57122 1063 10403 5347 83540 55143 9212 1058 1780 11130 54908 9735 699 91687 11004 8379 4085 79172 147841 3619 51433 64946 332 3796 51434 140735 401541 5905 8697 55166 64682 79902 64105 9793 991 79019 1783 80152	up	*
Peptide hormone metabolism	0.0016999	0.0361809	0.4550599	-0.4048911	-1.747169	54	338557 1636 6844 60559 7941 290 1066 6934 9314 590 25924 1509 3624 1522 4311 1359 55763 55770	down	*
G1/S Transition	0.0002267	0.0089133	0.5188481	0.4062681	1.739357	123	8318 55388 891 5558 1019 5426 990 7029 4173 4171 7298 993 4998 84515 81620 23649 4176 6241 4172 23594 5710 208 4331 6502 1163 983 5427 51053 1869 5693 5704 898 5686 5721 7083 3065 55957 5708 8317 5691 6117 4175 4174 5692 890 5557	up	**
Acrosome Reaction and Sperm:Oocyte Membrane Binding	0.0014351	0.0320135	0.4550599	-0.9433905	-1.737094	3	284359 928	down	*
Base Excision Repair	0.0016439	0.0353128	0.4550599	0.4836295	1.732836	44	5426 3980 23583 670 5425 3978 7515 142 5427 7374 55247 2237 8930 5424 5423 6117 5985 11284 8505 4350 79661 328 10038 25913 10714 5983 56655 5984	up	*
Signaling by TGFB family members	0.0002499	0.0095027	0.4984931	-0.3577463	-1.727106	94	4091 94 64388 650 23327 659 867 7048 387 9765 7323 1025 4092 3624 3726 23645 6498 10272 7314 7040 50855 7050 9372 4087 2280 7321 6497 4089 5500 23370 130399 5054 8812 9241 22938 905	down	**
GPCR ligand binding	0.0000063	0.0006615	0.6105269	-0.3024466	-1.710702	257	338557 2921 3061 2840 10268 58191 1910 1604 9002 3973 54361 5028 8477 10266 338442 6349 9034 10203 146 117 6915 728 1901 53829 59350 301 6751 7482 2793 8322 10316 153 2788 154 89780 151306 2828 5739 6367 6865 5724 6348 5029 2920 6351 5733 6846 5745 2796 7483 8698 8843 80835 50846 3269 148 5734 1236 57007 1880 5732 56670 6374 9283 7481 1233 2358 2787 59345 1230 2841 347148 6364 1235 23596 3362 7852 10803 5727	down	***
Assembly of the pre-replicative complex	0.0013462	0.0306192	0.4550599	0.4487548	1.710101	62	990 1871 4173 4171 4998 84515 81620 4176 1870 4172 23594 5710 51053 1869 5693 5704 5686 5721 5708 5691 4175 4174 5692	up	*
Mitotic G1 phase and G1/S transition	0.0001558	0.0066950	0.5188481	0.3915940	1.709367	141	8318 55388 891 5558 1019 5426 990 1871 7029 4173 4171 7298 993 4605 4998 84515 81620 7153 23649 4176 1870 6241 4172 23594 5710 208 4331 6502 1163 1031 983 5427 51053 1869 5693 5704 898 5686 5721 7083 3065 55957 5708 8317 5691 6117 4175 4174	up	**
Signaling by Interleukins	0.0000001	0.0000146	0.7049757	-0.2901528	-1.707531	365	55540 3552 3162 3553 2534 6349 4615 6844 1901 4205 998 9173 3557 5711 867 51561 948 301 23529 3977 1326 3936 2625 8809 7189 9987 1398 6935 4170 5782 3586 5606 6776 1845 6367 2308 834 5724 6809 8835 9655 6348 4790 1026 3687 28512 2920 3656 7431 6351 3575 759 11009 3055 6196 941 1270 5515 3569 9021 3560 3725 5682 6775 3726 3716 2889 9446 5295 2885 1385 5008 6195 5566 6950 7534 2353 7314 57162 5718 2309 5599 5516 7040 3181 7006 942 8660 5292 6648 1230 163702 6364 5306 3383 2247 3606 8807 1052 3320 23118 8767 3312 84868 54014 23198 4792 5062 1849 6095 9861 5715 3603 1265	down	***
S Phase	0.0001610	0.0067908	0.5188481	0.3871991	1.706333	150	8318 5558 9837 1019 5426 990 7029 4173 4171 993 4998 84515 84296 81620 23649 5425 4176 113130 4172 3978 23594 5710 208 4331 6502 1163 51433 5427 1869 5693 1763 51434 2237 5704 898 8697 5686 5721 157570 51659 51343 55957 64682 5424 5708 5691 6117 4175 4174 64785 5692 890 5557 29882 5985	up	**
Innate Immune System	0.0000000	0.0000000	0.9214260	-0.2686846	-1.669445	814	171568 10326 58484 6590 2219 4973 5175 84329 1604 8547 3553 4332 4048 847 401258 160364 9208 5787 126014 2534 960 9450 2205 10458 4615 1118 1727 342510 5049 728 10462 51646 4205 9844 998 4126 4688 9218 2517 5711 3916 6556 4775 2268 842 387 10628 948 57153 5611 4125 945 411 427 5906 115727 2760 64581 5648 1326 54941 290 5806 2040 3903 5530 140885 7189 22918 2896 8649 1398 7323 7295 51606 51552 526 965 1471 5606 2171 1675 1845 329 6386 4210 834 683 5724 5329 6093 2548 26578 51382 23643 1509 10533 64114 23071 4790 23406 3687 28512 5788 3656 6402 10855 245972 7099 64333 10096 6441 963 830 2207 10810 25801 3824 725 805 8560 124599 54918 10097 2720 3074 3055 138050 5870 3071 6196 5547 4641 5515 10163 4584 1520 5663 8773 712 3725 5682 10493 11031 3101 1522 5880 533 7305 54210 3304 23250 391 22875 8411 11010 5295 9535 5581 2885 1385 10892 284266 5269 6195 10487 5566 5336 2353 9114 7314 57162 801 5718 3384 221 5599 11277 3822 51411 1378 4311 5516 7077 100049587 10451 79930 1992 7006 2358 523 81619 5289 51143 527 53831 5534 975 3958 100528032 5005 25798 80301 102 9798 29099 201294 1235 27040 10109 3320 23118 8767 114548 3312 7321 60 23198 1387 25840 3385 930 81793 387921 4792 27180 1075 917 10092 5062 22914 1849 9342 9447 5023 83737 9861 8826 8804 5715 1265 196527 4069 2206 10006 7335 1535 535 10910 27202 713 1512 1848 55754 23200 1386 26253 727 5594 3683 54209 2512 653361 6279 326624	down	***
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	0.0011134	0.0263571	0.4550599	-0.3486402	-1.663464	88	2069 9365 2534 4615 2255 9173 1839 7189 5154 8395 255324 5527 5525 941 5515 374 5880 391 5295 2885 2264 152831 118788 5516 6801 942 8660 2247 5305 930 3815 2260 3084	down	*
Regulation of TP53 Activity through Phosphorylation	0.0023566	0.0471322	0.4317077	0.4118341	1.659494	82	11200 672 9212 22974 5932 9156 83695 6790 545 11073 1111 4193 83990 641 8445 1763 6878 5563 6794 5883 6749 26155 10111 11198 6117 890 5985 1020 7157 6874 5810 5571 7156 84126 80010 112858 5565 116028 5562 5983 580 5984 1432 8550	up	*
Signaling by NTRKs	0.0004341	0.0134273	0.4984931	-0.3253024	-1.648573	123	627 4066 2534 1959 8061 117 4205 10221 387 5906 1398 1845 5800 5978 3399 6016 3398 23237 6722 6196 3400 5515 6446 3726 2889 5295 2885 1385 6195 5899 2353 2354 5516 4664 8660 3727 7425 7074 135 1849 1958 1848 1386 5594 7529 57498 2033 4209	down	*
Separation of Sister Chromatids	0.0004487	0.0136976	0.4984931	0.3705551	1.645123	164	701 57122 1063 10403 347733 5347 83540 55143 9212 1058 9232 9700 1780 11130 54908 9735 699 91687 11004 8379 113130 4085 5710 79172 147841 3619 51433 64946 332 5693 3796 51434 140735 5704 401541 5905 8697 5686 7280 5721 113457 51807 55166 64682 5708 79902 64105 9793 5691 991 79019 1783 80152	up	*
Class A/1 (Rhodopsin-like receptors)	0.0000638	0.0031489	0.5384341	-0.3059107	-1.636640	183	338557 2921 3061 2840 58191 1910 9002 3973 5028 8477 338442 6349 9034 146 6915 728 1901 53829 59350 301 6751 10316 153 154 151306 2828 5739 6367 6865 5724 6348 5029 2920 6351 5733 6846 2796 8698 8843 3269 148 5734 1236 57007 1880 5732 56670 6374 9283 1233 2358 1230 2841 347148 6364 1235 23596 3362 7852 10803 135 1906 50865 10161 283869 27202 1269 1524 727 2357 624 2359 257313 53637 9290	down	**
Signaling by GPCR	0.0000000	0.0000019	0.7614608	-0.2684577	-1.636232	536	338557 5950 2921 3061 2840 10268 58191 2838 1910 338328 1604 9002 3973 54361 115 5028 8477 196883 8630 10266 2262 7222 22899 4023 5153 338442 6349 8787 9034 10203 146 117 6915 728 1901 53829 5573 998 59350 5143 3339 387 5138 301 6017 6751 1839 7482 2793 8322 10316 57406 153 5530 2788 154 10000 89780 9181 151306 5144 285440 5533 388 2828 9475 408 5739 6367 8526 6865 5724 6093 2869 5151 6348 5140 5029 2920 26084 6351 5733 6846 2776 23533 2771 5137 805 5745 2796 6196 7483 8698 8843 5515 23173 108 5145 5158 64407 80835 50846 3269 148 9639 5734 1236 5295 57007 5581 2885 1880 1385 5732 6195 5566 56670 6374 6003 9283 801 5582 1608 747 7481 1233 5516 10451 2358 2770 9187 2787 53831 5534 59345 1230 10672 340980 5997 2841 2868 5142 347148 6364 1235 23596 3362 409 7074 7852 29967 10803 5727	down	***
AURKA Activation by TPX2	0.0024891	0.0486730	0.4317077	0.4257428	1.630177	64	55722 4751 80321 5347 22974 10540 23354 11190 3161 6790 4957 9814 983 55835 80254 55125 7283 22981 9793 55755 54801 54930 22995 7840 22897 23332 80184 1778 10733 10142 5116	up	*
M Phase	0.0000101	0.0008404	0.5933255	0.3443692	1.622056	315	55722 10112 701 57122 4751 891 1063 10403 347733 80321 5347 83540 55143 9212 1058 9232 9700 9133 5578 1780 9918 11130 10540 54908 23354 11190 9493 9735 699 91687 9631 4957 9814 7175 11004 8379 64900 113130 4001 4085 5710 79172 147841 3619 54892 51433 983 55835 64946 332 64151 5693 3796 51434 23165 140735 5704 401541 3837 5905 653784 80097 80254 55125 8697 7283 5686 22981 7280 5721 113457 51807 55166 64682 5708 79902 64105 9793 5691 991 79019 27175 8086 92421 55755 1783 80152 54801 1104 54930 5692 22995 23636 7840 8815 29882 27229 22897 23175 55055 6396 29922 27243 10592 23383 1062 2801 221496 11065 23310 84790 5528 23225 23332 9688 23397 80184 79643 1778 10733 10142 5116 79980 5529 26271 5699 10844 5720 25936 7112	up	***
G alpha (q) signalling events	0.0003952	0.0125604	0.4984931	-0.3151297	-1.621575	141	338557 3061 2840 1910 9002 5028 8477 7222 146 6915 301 1839 2793 10316 57406 2788 2828 8526 6865 5724 2869 5029 6846 2776 2796 6196 64407 3269 148 5295 5581 2885 1385 6195 6003 1608 747 2358 2787 59345 5997 347148	down	*
RHO GTPases Activate Formins	0.0012352	0.0289472	0.4550599	0.3757329	1.603814	120	701 57122 1063 10403 347733 5347 83540 55143 9212 1058 1780 11130 54908 9735 699 91687 11004 8379 5217 4085 79172 147841 3619 64946 332 3796 140735 81624 401541 5905 389 1857 7280 113457 51807 55166 79902 64105 9793 991 79019 1783 80152	up	*
Intra-Golgi and retrograde Golgi-to-ER traffic	0.0006354	0.0171399	0.4772708	0.3539238	1.588924	184	547 113220 147700 10112 146909 347733 29127 9609 1780 9276 55582 10540 9493 636 56992 26958 22820 5050 9371 10652 11004 22836 3832 11014 3797 23423 4905 3798 53407 124602 3796 140735 51560 9950 10139 7280 113457 22796 91949 3835 381 51807 55605 9585 25839 64837 89953 11015 9382 8729 4124 1783 23046 10244 55275 9570 22818 55738 10466 9266 1314 60592 54732 339122 9527 1062 51226 84790 10226 11316 1778 9265 9648 22920 79571 57511 23647 221458 400 662 51594 11127 11258 9827 10905 23303 8677 84516	up	*
Negative regulation of the PI3K/AKT network	0.0024614	0.0486730	0.4317077	-0.3262767	-1.585857	95	2069 9365 2534 4615 2255 9173 1839 7189 10000 5154 8395 255324 5527 5525 941 5515 374 5880 391 5295 2885 2264 152831 118788 5516 6801 942 8660 23035 2247 5305 930 3815 5728 2260 3084	down	*
Organelle biogenesis and maintenance	0.0001244	0.0054465	0.5188481	0.3447221	1.582013	236	55722 84902 23322 4751 84303 117177 54903 347733 55764 79989 80321 5347 11020 11336 10576 10540 23354 11190 6604 582 9371 85302 60412 22948 4957 9814 112752 26160 3797 1258 26005 3418 9657 983 6742 79598 55835 7203 79867 140735 6608 5563 51098 54927 80254 129880 55125 4867 23265 7283 22981 7280 113457 51807 1262 55735 4899 26146 9793 23409 8729 79600 55755 57539 23408 54801 79659 2101 54930 84747 22995 27077 7840 22897 23059 57787 200132 150737 84790 23332 347240 5571 51106 80184 5442 1778 10733 133522 10142 5116 9727 22920	up	**
Hemostasis	0.0000001	0.0000205	0.7049757	-0.2652445	-1.575267	488	51378 7465 51266 7010 4973 5175 2624 6693 7123 5593 9002 5028 81027 7056 23186 7222 2534 22915 960 5153 1521 857 90952 6915 5573 998 928 2621 2268 387 5138 948 490 10019 9056 11069 5906 2793 3678 308 23657 57406 2625 83700 2788 140885 1398 5552 5154 84617 965 388 10749 1675 408 5739 8526 3778 5329 23428 7057 4097 4352 26153 10257 3705 23348 3687 3779 6402 6403 58494 830 2207 5341 5527 5525 2776 23533 2771 805 23764 7450 7042 10544 5547 6546 5515 9749 91768 51706 5271 962 8654 5880 54210 391 5295 2995 5581 2885 5269 10487 5566 81704 7534 8795 8407 5336 6520 801 30846 5582 1608 972 747 5516 6814 7040 10938 10451 54495 29802 55664 2770 2787 6547 59345 334 9046 5005 2627 10672 88 57572 6404 27040 9948 7035 409 5868 60 25942 10411 221037 7975 7078 55619 5592 5023 23095 9732 23414 30845 8793 3660 3831 5054 832 23052 5594 10184 5583 3683 3688 135228 7846 481 5294 5768 64780 2791 682	down	***
Mitotic Metaphase and Anaphase	0.0006296	0.0171399	0.4772708	0.3451016	1.558733	207	701 57122 891 1063 10403 347733 5347 83540 55143 9212 1058 9232 9700 9133 1780 11130 54908 9735 699 91687 9631 11004 8379 113130 4001 4085 5710 79172 147841 3619 51433 983 64946 332 5693 3796 51434 23165 140735 5704 401541 3837 5905 8697 5686 7280 5721 113457 51807 55166 64682 5708 79902 64105 9793 5691 991 79019 92421 1783 80152 1104 5692 23636 8815 29882 55055 6396 27243 1062 221496 11065 84790 5528 23332 9688 79643 1778 79980 5529 26271 5699 5720 25936 7112	up	*
GPCR downstream signalling	0.0000002	0.0000287	0.6901325	-0.2625839	-1.552899	489	338557 5950 2921 3061 2840 10268 58191 2838 1910 338328 9002 3973 115 5028 8477 196883 8630 10266 2262 7222 22899 4023 5153 338442 8787 10203 146 117 6915 728 53829 5573 998 59350 5143 3339 387 5138 301 6017 6751 1839 2793 10316 57406 153 5530 2788 154 10000 9181 151306 5144 285440 5533 388 2828 9475 408 5739 8526 6865 5724 6093 2869 5151 5140 5029 2920 26084 6351 5733 6846 2776 23533 2771 5137 805 5745 2796 6196 8698 8843 5515 23173 108 5145 5158 64407 80835 3269 148 9639 5734 1236 5295 57007 5581 2885 1880 1385 5732 6195 5566 56670 6374 6003 9283 801 5582 1608 747 1233 5516 10451 2358 2770 9187 2787 53831 5534 59345 1230 10672 340980 5997 2841 2868 5142 347148 6364 1235 23596 3362 409 7074 7852 29967	down	***
Mitotic Anaphase	0.0008576	0.0218629	0.4772708	0.3435234	1.551903	206	701 57122 891 1063 10403 347733 5347 83540 55143 9212 1058 9232 9700 9133 1780 11130 54908 9735 699 91687 9631 11004 8379 113130 4001 4085 5710 79172 147841 3619 51433 983 64946 332 5693 3796 51434 23165 140735 5704 401541 3837 5905 8697 5686 7280 5721 113457 51807 55166 64682 5708 79902 64105 9793 5691 991 79019 92421 1783 80152 1104 5692 23636 8815 29882 55055 6396 27243 1062 221496 11065 84790 5528 23332 9688 79643 1778 79980 5529 5699 5720 25936 7112	up	*
Mitotic G2-G2/M phases	0.0020581	0.0422540	0.4317077	0.3429221	1.532123	176	2305 55722 4751 891 1063 347733 51512 80321 5347 22974 1871 9133 993 4605 10540 23354 11190 3161 8945 6790 4957 9814 995 5710 9088 4331 983 55835 1869 5693 5704 653784 80097 80254 55125 7283 5686 22981 7280 5721 113457 51807 55957 5708 51400 9793 5691 27175 55755 54801 54930 5692 22995 7840 890 27229 22897 23291 29922 7157 994 84790 23332 80184 1778 10733 10142 5116 984 5699 51451 10844 5720	up	*
ESR-mediated signaling	0.0005189	0.0148632	0.4772708	-0.2991803	-1.525756	148	2069 9687 857 1839 2793 3315 858 2625 2788 10000 192670 192669 1025 1509 255324 2771 805 8648 6722 23189 374 9166 3725 5295 1655 1385 2353 801 2309 2354 6801 2770 2787 59345 8850 5481 3727 3320 340481 1387 2963 8877 10524 1027 1386 5594 2791 5441 5885 2033 5431 2494 865 904 8503 2066 4893 27161 2957	down	*
Alanine metabolism	0.0004063	0.0127389	0.4984931	0.9888758	1.509981	2	2875 84706	up	*
Intracellular signaling by second messengers	0.0016126	0.0349641	0.4550599	-0.2451304	-1.400352	267	2069 5468 115 196883 9365 23186 2534 5153 4615 2255 5573 9173 5711 842 64121 1839 3164 7189 8649 10000 5154 192670 6615 192669 2308 8395 5978 1026 255324 5527 5525 5137 805 941 5515 108 374 3725 5682 5880 391 5295 5581 2885 1385 5566 80243 81847 2264 7314 801 152831 7874 5718 2309 5582 118788 5516 6801 942 8660 1459 23035 6045 2247 5305 23198 930 3815 5728 2260 3084 9861 5715 79109 648	down	*
Cytokine Signaling in Immune system	0.0000289	0.0017554	0.5756103	-0.2203534	-1.373885	710	2069 55540 3552 3162 7010 3553 5593 53371 9693 9365 2534 960 6349 25939 9462 4615 6844 1901 2255 4205 998 9173 3557 5711 867 51561 948 301 1973 943 23529 1839 6868 3977 5906 115727 1326 10437 10048 152559 3936 1977 2625 8809 7189 9987 8649 1398 6711 6935 4170 5154 3841 5782 3586 5606 6776 408 1845 6367 2308 329 834 80128 8742 5724 5623 9966 6809 8835 9655 6348 4790 1026 5140 3687 28512 255324 2920 3656 7431 6351 1843 5527 5525 3575 759 3839 3117 805 11009 4140 7450 8554 3055 6196 941 1270 5515 374 3569 9021 3560 8638 3725 5682 6775 3726 8036 3459 3716 1850 2889 9446 5295 3394 2885 1385 5008 6195 5566 6950 3604 7534 2264 2353 7314 57162 801 152831 8741 5718 2309 5599 3663 5516 9972 7040 3181 8682 7006 201626 1847 3454 5289 942 8660 5292 6648 1230 88 163702 6364 5306 3383 2247 3606 8807 27040 409 1052 3320 23118 8767 25820 3312 60 6672 84868 54014 23198 4928 3840 8452 4792 5979 3815 5062 1849 8744 2260 6095 3084 9861 4502 8826 5715 3603 1974 23279 1265 1982 5500 3660 1437 7335 1958 970 1439 2690 944 1848	down	**
Latent infection - Other responses of Mtb to phagocytosis	0.0019916	0.0412541	0.4317077	0.9989495	1.343894	1	4057	up	*
Mtb iron assimilation by chelation	0.0019916	0.0412541	0.4317077	0.9989495	1.343894	1	4057	up	*
Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI)	0.0021988	0.0447484	0.4317077	-0.9988877	-1.329992	1	123041	down	*

KEGG pathway analysis

pathway_id	pathway	p.geomean	stat.mean	p.val	q.val	set.size	state	pvlabel
hsa04080	Neuroactive ligand-receptor interaction	0.0000701	3.863383	0.0000701	0.0145839	146	up	***
hsa04950	Maturity onset diabetes of the young	0.0066825	2.878318	0.0066825	0.2551793	11	up	**
hsa04940	Type I diabetes mellitus	0.0037492	2.877860	0.0037492	0.2551793	21	up	**
hsa05143	African trypanosomiasis	0.0052398	2.664072	0.0052398	0.2551793	30	up	**
hsa05332	Graft-versus-host disease	0.0082541	2.594803	0.0082541	0.2551793	17	up	**
hsa04640	Hematopoietic cell lineage	0.0074036	2.469363	0.0074036	0.2551793	71	up	**
hsa05144	Malaria	0.0097380	2.389421	0.0097380	0.2551793	45	up	**
hsa04060	Cytokine-cytokine receptor interaction	0.0098146	2.344185	0.0098146	0.2551793	181	up	**
hsa05320	Autoimmune thyroid disease	0.0200749	2.153768	0.0200749	0.4175573	18	up	*
hsa05323	Rheumatoid arthritis	0.0175000	2.136476	0.0175000	0.4044448	66	up	*
hsa05150	Staphylococcus aureus infection	0.0248082	2.004328	0.0248082	0.4691009	32	up	*
hsa05330	Allograft rejection	0.0286342	1.990957	0.0286342	0.4767704	17	up	*
hsa04976	Bile secretion	0.0297982	1.908024	0.0297982	0.4767704	51	up	*
hsa03320	PPAR signaling pathway	0.0379134	1.795074	0.0379134	0.5632848	52	up	*
hsa00590	Arachidonic acid metabolism	0.0434143	1.734070	0.0434143	0.5706989	42	up	*
hsa04512	ECM-receptor interaction	0.0451219	1.706192	0.0451219	0.5706989	71	up	*
hsa04514	Cell adhesion molecules (CAMs)	0.0466437	1.686353	0.0466437	0.5706989	101	up	*

Gene Ontology analysis

pathway_id	pathway	p.geomean	stat.mean	p.val	q.val	set.size	state	pvlabel
GO:0009986	cell surface	0.0000011	4.772466	0.0000011	0.0056734	409	up	***
GO:0031012	extracellular matrix	0.0000076	4.360352	0.0000076	0.0089319	336	up	***
GO:0015267	channel activity	0.0000089	4.331811	0.0000089	0.0089319	270	up	***
GO:0022803	passive transmembrane transporter activity	0.0000089	4.331811	0.0000089	0.0089319	270	up	***
GO:0005578	proteinaceous extracellular matrix	0.0000098	4.310014	0.0000098	0.0089319	287	up	***
GO:0022838	substrate-specific channel activity	0.0000103	4.300570	0.0000103	0.0089319	257	up	***
GO:0005216	ion channel activity	0.0000280	4.065323	0.0000280	0.0200786	252	up	***
GO:0016337	cell-cell adhesion	0.0000308	4.036891	0.0000308	0.0200786	299	up	***
GO:0007156	homophilic cell adhesion	0.0001290	3.740454	0.0001290	0.0748520	84	up	***
GO:0005506	iron ion binding	0.0001613	3.661669	0.0001613	0.0842281	117	up	***
GO:0007586	digestion	0.0002537	3.630668	0.0002537	0.1103644	55	up	***
GO:0020037	heme binding	0.0002080	3.596448	0.0002080	0.0987041	97	up	***
GO:0004497	monooxygenase activity	0.0002970	3.530083	0.0002970	0.1144525	66	up	***
GO:0008009	chemokine activity	0.0006261	3.467401	0.0006261	0.1144525	26	up	***
GO:0009897	external side of plasma membrane	0.0003256	3.443297	0.0003256	0.1144525	168	up	***
GO:0035270	endocrine system development	0.0004773	3.386871	0.0004773	0.1144525	86	up	***
GO:0006820	anion transport	0.0003894	3.383564	0.0003894	0.1144525	241	up	***
GO:0044420	extracellular matrix part	0.0004415	3.368042	0.0004415	0.1144525	145	up	***
GO:0022836	gated channel activity	0.0004279	3.360354	0.0004279	0.1144525	203	up	***
GO:0022839	ion gated channel activity	0.0004279	3.360354	0.0004279	0.1144525	203	up	***
GO:0034702	ion channel complex	0.0004711	3.347664	0.0004711	0.1144525	128	up	***
GO:0004930	G-protein coupled receptor activity	0.0004564	3.335724	0.0004564	0.1144525	257	up	***
GO:0046906	tetrapyrrole binding	0.0005241	3.327151	0.0005241	0.1144525	104	up	***
GO:0016324	apical plasma membrane	0.0005437	3.304063	0.0005437	0.1144525	161	up	***
GO:0033993	response to lipid	0.0005100	3.297458	0.0005100	0.1144525	427	up	***
GO:0006954	inflammatory response	0.0005598	3.271979	0.0005598	0.1144525	383	up	***
GO:0005125	cytokine activity	0.0006357	3.264550	0.0006357	0.1144525	122	up	***
GO:0030855	epithelial cell differentiation	0.0006118	3.256958	0.0006118	0.1144525	218	up	***
GO:0004867	serine-type endopeptidase inhibitor activity	0.0008112	3.254930	0.0008112	0.1321288	55	up	***
GO:0001568	blood vessel development	0.0006137	3.243412	0.0006137	0.1144525	433	up	***
GO:0048514	blood vessel morphogenesis	0.0007653	3.180710	0.0007653	0.1321288	381	up	***
GO:0050900	leukocyte migration	0.0008351	3.164454	0.0008351	0.1321288	219	up	***
GO:0001944	vasculature development	0.0008255	3.156386	0.0008255	0.1321288	455	up	***
GO:0010035	response to inorganic substance	0.0008703	3.149214	0.0008703	0.1336377	259	up	***
GO:0008544	epidermis development	0.0009927	3.117977	0.0009927	0.1408667	186	up	***
GO:0045165	cell fate commitment	0.0010523	3.108098	0.0010523	0.1408667	147	up	**
GO:0060429	epithelium development	0.0009860	3.103384	0.0009860	0.1408667	473	up	***
GO:0010817	regulation of hormone levels	0.0010218	3.100855	0.0010218	0.1408667	268	up	**
GO:0050878	regulation of body fluid levels	0.0010282	3.090697	0.0010282	0.1408667	490	up	**
GO:0015291	secondary active transmembrane transporter activity	0.0012027	3.070855	0.0012027	0.1569833	137	up	**
GO:0051046	regulation of secretion	0.0012885	3.026666	0.0012885	0.1640824	334	up	**
GO:0048729	tissue morphogenesis	0.0013641	3.006986	0.0013641	0.1695767	395	up	**
GO:0070330	aromatase activity	0.0030866	3.003529	0.0030866	0.2369846	15	up	**
GO:0032101	regulation of response to external stimulus	0.0014427	2.993250	0.0014427	0.1751704	296	up	**
GO:0006959	humoral immune response	0.0017755	2.964792	0.0017755	0.1967506	86	up	**
GO:0022600	digestive system process	0.0022956	2.962692	0.0022956	0.2140219	36	up	**
GO:0046873	metal ion transmembrane transporter activity	0.0016732	2.948208	0.0016732	0.1967506	270	up	**
GO:0045177	apical part of cell	0.0017549	2.938638	0.0017549	0.1967506	215	up	**
GO:0005509	calcium ion binding	0.0017228	2.932105	0.0017228	0.1967506	488	up	**
GO:0044057	regulation of system process	0.0018089	2.921078	0.0018089	0.1967506	340	up	**
GO:0030414	peptidase inhibitor activity	0.0019882	2.920571	0.0019882	0.1976825	98	up	**
GO:0002526	acute inflammatory response	0.0020825	2.918234	0.0020825	0.1976825	83	up	**
GO:0003823	antigen binding	0.0025366	2.916650	0.0025366	0.2278522	34	up	**
GO:0021675	nerve development	0.0023727	2.905612	0.0023727	0.2173337	46	up	**
GO:0097367	carbohydrate derivative binding	0.0019890	2.905492	0.0019890	0.1976825	143	up	**
GO:0005261	cation channel activity	0.0019508	2.903362	0.0019508	0.1976825	197	up	**
GO:0042379	chemokine receptor binding	0.0027058	2.903333	0.0027058	0.2278522	33	up	**
GO:0043062	extracellular structure organization	0.0019967	2.901669	0.0019967	0.1976825	170	up	**
GO:0030198	extracellular matrix organization	0.0020653	2.890932	0.0020653	0.1976825	169	up	**
GO:0048483	autonomic nervous system development	0.0029407	2.883728	0.0029407	0.2339023	28	up	**
GO:0051240	positive regulation of multicellular organismal process	0.0020717	2.876241	0.0020717	0.1976825	410	up	**
GO:0005581	collagen	0.0026337	2.846995	0.0026337	0.2278522	68	up	**
GO:0051093	negative regulation of developmental process	0.0025885	2.803949	0.0025885	0.2278522	424	up	**
GO:0005882	intermediate filament	0.0032508	2.796302	0.0032508	0.2459741	49	up	**
GO:0001525	angiogenesis	0.0026936	2.792910	0.0026936	0.2278522	315	up	**
GO:0000780	condensed nuclear chromosome, centromeric region	0.0049803	2.786266	0.0049803	0.2910210	14	up	**
GO:0032504	multicellular organism reproduction	0.0027761	2.780321	0.0027761	0.2300652	454	up	**
GO:0005539	glycosaminoglycan binding	0.0029568	2.777578	0.0029568	0.2339023	130	up	**
GO:0051606	detection of stimulus	0.0030445	2.775176	0.0030445	0.2369846	114	up	**
GO:0008285	negative regulation of cell proliferation	0.0028489	2.771835	0.0028489	0.2324113	445	up	**
GO:0003777	microtubule motor activity	0.0035255	2.753194	0.0035255	0.2555646	68	up	**
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	0.0050518	2.750394	0.0050518	0.2910210	18	up	**
GO:0046683	response to organophosphorus	0.0035917	2.741756	0.0035917	0.2555646	73	up	**
GO:0005858	axonemal dynein complex	0.0057694	2.736003	0.0057694	0.2910210	14	up	**
GO:0009617	response to bacterium	0.0033095	2.729344	0.0033095	0.2468420	233	up	**
GO:0015711	organic anion transport	0.0034265	2.718936	0.0034265	0.2519674	203	up	**
GO:0042445	hormone metabolic process	0.0036712	2.708512	0.0036712	0.2555646	111	up	**
GO:0048609	multicellular organismal reproductive process	0.0036633	2.688265	0.0036633	0.2555646	449	up	**
GO:0001655	urogenital system development	0.0037709	2.684155	0.0037709	0.2590475	237	up	**
GO:0003774	motor activity	0.0042308	2.663291	0.0042308	0.2868675	112	up	**
GO:0016266	O-glycan processing	0.0050178	2.661522	0.0050178	0.2910210	46	up	**
GO:0031016	pancreas development	0.0048453	2.658240	0.0048453	0.2910210	50	up	**
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	0.0048978	2.650128	0.0048978	0.2910210	56	up	**
GO:0031225	anchored to membrane	0.0044077	2.647729	0.0044077	0.2910210	96	up	**
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	0.0051524	2.639566	0.0051524	0.2910210	51	up	**
GO:0004866	endopeptidase inhibitor activity	0.0046228	2.634648	0.0046228	0.2910210	93	up	**
GO:0007588	excretion	0.0051138	2.631048	0.0051138	0.2910210	45	up	**
GO:0007389	pattern specification process	0.0044931	2.621974	0.0044931	0.2910210	292	up	**
GO:0031018	endocrine pancreas development	0.0061333	2.616600	0.0061333	0.2910210	32	up	**
GO:0007218	neuropeptide signaling pathway	0.0052452	2.613089	0.0052452	0.2910210	49	up	**
GO:0008037	cell recognition	0.0052373	2.605154	0.0052373	0.2910210	58	up	**
GO:0030593	neutrophil chemotaxis	0.0057561	2.597025	0.0057561	0.2910210	47	up	**
GO:0022804	active transmembrane transporter activity	0.0049559	2.591708	0.0049559	0.2910210	229	up	**
GO:0043583	ear development	0.0050700	2.589586	0.0050700	0.2910210	141	up	**
GO:0055065	metal ion homeostasis	0.0050327	2.583836	0.0050327	0.2910210	267	up	**
GO:0005201	extracellular matrix structural constituent	0.0058517	2.575077	0.0058517	0.2910210	61	up	**
GO:0014070	response to organic cyclic compound	0.0051084	2.574624	0.0051084	0.2910210	413	up	**
GO:0008083	growth factor activity	0.0053757	2.574360	0.0053757	0.2910210	111	up	**
GO:0007268	synaptic transmission	0.0051333	2.572097	0.0051333	0.2910210	469	up	**
GO:0005796	Golgi lumen	0.0063544	2.561236	0.0063544	0.2910210	51	up	**
GO:0072001	renal system development	0.0054189	2.560337	0.0054189	0.2910210	205	up	**
GO:0014074	response to purine-containing compound	0.0059374	2.551641	0.0059374	0.2910210	86	up	**
GO:0015081	sodium ion transmembrane transporter activity	0.0060128	2.547715	0.0060128	0.2910210	85	up	**
GO:0001664	G-protein coupled receptor binding	0.0057369	2.546575	0.0057369	0.2910210	139	up	**
GO:0051047	positive regulation of secretion	0.0057754	2.540793	0.0057754	0.2910210	167	up	**
GO:0015293	symporter activity	0.0061288	2.538180	0.0061288	0.2910210	90	up	**
GO:0061135	endopeptidase regulator activity	0.0061022	2.533411	0.0061022	0.2910210	97	up	**
GO:0008509	anion transmembrane transporter activity	0.0059363	2.532937	0.0059363	0.2910210	145	up	**
GO:0050727	regulation of inflammatory response	0.0060084	2.528379	0.0060084	0.2910210	148	up	**
GO:0015103	inorganic anion transmembrane transporter activity	0.0064437	2.527159	0.0064437	0.2925458	63	up	**
GO:0034707	chloride channel complex	0.0078314	2.526957	0.0078314	0.3219498	23	up	**
GO:0010038	response to metal ion	0.0060141	2.525763	0.0060141	0.2910210	175	up	**
GO:0015276	ligand-gated ion channel activity	0.0063494	2.520885	0.0063494	0.2910210	89	up	**
GO:0022834	ligand-gated channel activity	0.0063494	2.520885	0.0063494	0.2910210	89	up	**
GO:0048839	inner ear development	0.0063195	2.514023	0.0063195	0.2910210	121	up	**
GO:0010876	lipid localization	0.0062241	2.512506	0.0062241	0.2910210	191	up	**
GO:0002455	humoral immune response mediated by circulating immunoglobulin	0.0072252	2.512503	0.0072252	0.3082675	40	up	**
GO:0015721	bile acid and bile salt transport	0.0132076	2.499466	0.0132076	0.3727396	10	up	*
GO:0005230	extracellular ligand-gated ion channel activity	0.0077855	2.486228	0.0077855	0.3219498	41	up	**
GO:0008201	heparin binding	0.0070989	2.476367	0.0070989	0.3082675	99	up	**
GO:0018958	phenol-containing compound metabolic process	0.0077743	2.473362	0.0077743	0.3219498	46	up	**
GO:0006805	xenobiotic metabolic process	0.0071559	2.473258	0.0071559	0.3082675	100	up	**
GO:0071466	cellular response to xenobiotic stimulus	0.0071559	2.473258	0.0071559	0.3082675	100	up	**
GO:0048562	embryonic organ morphogenesis	0.0070409	2.469632	0.0070409	0.3082675	158	up	**
GO:0055080	cation homeostasis	0.0070745	2.460583	0.0070745	0.3082675	332	up	**
GO:0048732	gland development	0.0073214	2.451558	0.0073214	0.3082675	225	up	**
GO:0050817	coagulation	0.0072355	2.450695	0.0072355	0.3082675	422	up	**
GO:0030001	metal ion transport	0.0073172	2.446651	0.0073172	0.3082675	405	up	**
GO:0015108	chloride transmembrane transporter activity	0.0086773	2.432958	0.0086773	0.3259614	42	up	**
GO:0000982	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity	0.0084366	2.425531	0.0084366	0.3259614	78	up	**
GO:0045168	cell-cell signaling involved in cell fate commitment	0.0100043	2.419541	0.0100043	0.3399639	28	up	*
GO:0021545	cranial nerve development	0.0095733	2.419177	0.0095733	0.3354514	27	up	**
GO:0030856	regulation of epithelial cell differentiation	0.0089274	2.414538	0.0089274	0.3259614	51	up	**
GO:0042472	inner ear morphogenesis	0.0086497	2.414412	0.0086497	0.3259614	67	up	**
GO:0050729	positive regulation of inflammatory response	0.0087989	2.413751	0.0087989	0.3259614	55	up	**
GO:0048232	male gamete generation	0.0081081	2.412383	0.0081081	0.3259614	258	up	**
GO:0048545	response to steroid hormone stimulus	0.0081886	2.411602	0.0081886	0.3259614	197	up	**
GO:0007599	hemostasis	0.0082059	2.404692	0.0082059	0.3259614	422	up	**
GO:0006875	cellular metal ion homeostasis	0.0083656	2.401689	0.0083656	0.3259614	248	up	**
GO:0007283	spermatogenesis	0.0084322	2.397925	0.0084322	0.3259614	257	up	**
GO:0007596	blood coagulation	0.0083880	2.396638	0.0083880	0.3259614	419	up	**
GO:0006775	fat-soluble vitamin metabolic process	0.0106103	2.396280	0.0106103	0.3506102	23	up	*
GO:0030155	regulation of cell adhesion	0.0085017	2.395818	0.0085017	0.3259614	236	up	**
GO:1901701	cellular response to oxygen-containing compound	0.0084865	2.393755	0.0084865	0.3259614	334	up	**
GO:0015077	monovalent inorganic cation transmembrane transporter activity	0.0087570	2.385282	0.0087570	0.3259614	234	up	**
GO:0006493	protein O-linked glycosylation	0.0097012	2.385101	0.0097012	0.3376677	61	up	**
GO:1901342	regulation of vasculature development	0.0089279	2.383059	0.0089279	0.3259614	144	up	**
GO:0051050	positive regulation of transport	0.0088329	2.377563	0.0088329	0.3259614	398	up	**
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	0.0091401	2.372129	0.0091401	0.3313915	188	up	**
GO:0002544	chronic inflammatory response	0.0130920	2.366947	0.0130920	0.3725465	14	up	*
GO:0031128	developmental induction	0.0114705	2.366724	0.0114705	0.3629543	27	up	*
GO:0016323	basolateral plasma membrane	0.0093908	2.366446	0.0093908	0.3335343	121	up	**
GO:0009410	response to xenobiotic stimulus	0.0095074	2.366041	0.0095074	0.3353932	102	up	**
GO:0006869	lipid transport	0.0093679	2.363811	0.0093679	0.3335343	168	up	**
GO:0007610	behavior	0.0093698	2.355907	0.0093698	0.3335343	384	up	**
GO:0021602	cranial nerve morphogenesis	0.0127916	2.353367	0.0127916	0.3725465	16	up	*
GO:0048565	digestive tract development	0.0100418	2.349211	0.0100418	0.3399639	85	up	*
GO:0005254	chloride channel activity	0.0114292	2.347604	0.0114292	0.3629543	29	up	*
GO:0050663	cytokine secretion	0.0103219	2.344782	0.0103219	0.3454533	72	up	*
GO:0043627	response to estrogen stimulus	0.0100928	2.344735	0.0100928	0.3399639	100	up	*
GO:1901615	organic hydroxy compound metabolic process	0.0098564	2.338218	0.0098564	0.3385806	305	up	**
GO:0007186	G-protein coupled receptor signaling pathway	0.0098572	2.336732	0.0098572	0.3385806	380	up	**
GO:0002673	regulation of acute inflammatory response	0.0111966	2.329939	0.0111966	0.3586337	43	up	*
GO:0048485	sympathetic nervous system development	0.0155585	2.326859	0.0155585	0.3944535	13	up	*
GO:0001539	ciliary or flagellar motility	0.0124042	2.325271	0.0124042	0.3683484	24	up	*
GO:0005126	cytokine receptor binding	0.0104068	2.325070	0.0104068	0.3460774	145	up	*
GO:0090307	spindle assembly involved in mitosis	0.0151227	2.311348	0.0151227	0.3931771	13	up	*
GO:0030595	leukocyte chemotaxis	0.0111195	2.306907	0.0111195	0.3586337	102	up	*
GO:0050707	regulation of cytokine secretion	0.0118796	2.297701	0.0118796	0.3660027	58	up	*
GO:0007600	sensory perception	0.0110732	2.294112	0.0110732	0.3586337	302	up	*
GO:0003001	generation of a signal involved in cell-cell signaling	0.0111602	2.292580	0.0111602	0.3586337	251	up	*
GO:0023061	signal release	0.0111602	2.292580	0.0111602	0.3586337	251	up	*
GO:0001657	ureteric bud development	0.0117308	2.288985	0.0117308	0.3660027	79	up	*
GO:0070293	renal absorption	0.0176898	2.280586	0.0176898	0.4105554	11	up	*
GO:0061134	peptidase regulator activity	0.0117726	2.279243	0.0117726	0.3660027	132	up	*
GO:0042471	ear morphogenesis	0.0121363	2.275943	0.0121363	0.3683484	82	up	*
GO:0030141	secretory granule	0.0119173	2.270950	0.0119173	0.3660027	178	up	*
GO:0042493	response to drug	0.0119032	2.267668	0.0119032	0.3660027	264	up	*
GO:0034703	cation channel complex	0.0122957	2.266188	0.0122957	0.3683484	95	up	*
GO:0045787	positive regulation of cell cycle	0.0125246	2.264056	0.0125246	0.3694394	94	up	*
GO:1901681	sulfur compound binding	0.0123496	2.260173	0.0123496	0.3683484	132	up	*
GO:0061138	morphogenesis of a branching epithelium	0.0122674	2.260114	0.0122674	0.3683484	153	up	*
GO:0030104	water homeostasis	0.0156057	2.259037	0.0156057	0.3944535	17	up	*
GO:0044456	synapse part	0.0124170	2.251142	0.0124170	0.3683484	249	up	*
GO:0051983	regulation of chromosome segregation	0.0150666	2.245567	0.0150666	0.3931771	23	up	*
GO:0061008	hepaticobiliary system development	0.0133110	2.242712	0.0133110	0.3736377	79	up	*
GO:0045765	regulation of angiogenesis	0.0128940	2.242708	0.0128940	0.3725465	132	up	*
GO:0030900	forebrain development	0.0128999	2.238997	0.0128999	0.3725465	203	up	*
GO:0097305	response to alcohol	0.0129953	2.236724	0.0129953	0.3725465	177	up	*
GO:0005911	cell-cell junction	0.0130572	2.231726	0.0130572	0.3725465	236	up	*
GO:0035085	cilium axoneme	0.0140879	2.231089	0.0140879	0.3850948	47	up	*
GO:0097014	microtubule-based flagellar cytoplasm	0.0140879	2.231089	0.0140879	0.3850948	47	up	*
GO:0022890	inorganic cation transmembrane transporter activity	0.0131294	2.227515	0.0131294	0.3725465	344	up	*
GO:0005875	microtubule associated complex	0.0135547	2.227174	0.0135547	0.3747160	119	up	*
GO:2000826	regulation of heart morphogenesis	0.0177646	2.225840	0.0177646	0.4105554	18	up	*
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	0.0135647	2.223769	0.0135647	0.3747160	126	up	*
GO:0005929	cilium	0.0134185	2.221837	0.0134185	0.3746428	213	up	*
GO:0002675	positive regulation of acute inflammatory response	0.0177581	2.203496	0.0177581	0.4105554	18	up	*
GO:0015701	bicarbonate transport	0.0177063	2.199020	0.0177063	0.4105554	22	up	*
GO:0003013	circulatory system process	0.0141992	2.198454	0.0141992	0.3861151	260	up	*
GO:0030857	negative regulation of epithelial cell differentiation	0.0201983	2.196764	0.0201983	0.4228719	13	up	*
GO:0042742	defense response to bacterium	0.0150155	2.196434	0.0150155	0.3931771	67	up	*
GO:0009055	electron carrier activity	0.0145168	2.195822	0.0145168	0.3927067	127	up	*
GO:0005267	potassium channel activity	0.0149386	2.192882	0.0149386	0.3931771	75	up	*
GO:0006956	complement activation	0.0159944	2.191905	0.0159944	0.4008572	39	up	*
GO:0001889	liver development	0.0151367	2.191352	0.0151367	0.3931771	77	up	*
GO:0035150	regulation of tube size	0.0153375	2.184915	0.0153375	0.3944535	88	up	*
GO:0050880	regulation of blood vessel size	0.0153375	2.184915	0.0153375	0.3944535	88	up	*
GO:0006873	cellular ion homeostasis	0.0147276	2.180714	0.0147276	0.3931771	483	up	*
GO:0008015	blood circulation	0.0150302	2.175860	0.0150302	0.3931771	259	up	*
GO:0007017	microtubule-based process	0.0150474	2.173189	0.0150474	0.3931771	380	up	*
GO:0006953	acute-phase response	0.0180744	2.172932	0.0180744	0.4105554	30	up	*
GO:0007605	sensory perception of sound	0.0156386	2.171833	0.0156386	0.3944535	97	up	*
GO:0051591	response to cAMP	0.0165068	2.169276	0.0165068	0.4065188	49	up	*
GO:0015718	monocarboxylic acid transport	0.0161228	2.165368	0.0161228	0.4008572	72	up	*
GO:0045766	positive regulation of angiogenesis	0.0161234	2.162668	0.0161234	0.4008572	76	up	*
GO:0035295	tube development	0.0156391	2.157736	0.0156391	0.3944535	368	up	*
GO:0030510	regulation of BMP signaling pathway	0.0170364	2.155914	0.0170364	0.4080149	50	up	*
GO:0005253	anion channel activity	0.0174457	2.155608	0.0174457	0.4105554	36	up	*
GO:0009581	detection of external stimulus	0.0166376	2.151909	0.0166376	0.4078158	73	up	*
GO:0019825	oxygen binding	0.0199512	2.145511	0.0199512	0.4228719	20	up	*
GO:0005003	ephrin receptor activity	0.0212410	2.144917	0.0212410	0.4268051	13	up	*
GO:0007018	microtubule-based movement	0.0164768	2.144614	0.0164768	0.4065188	149	up	*
GO:0003018	vascular process in circulatory system	0.0170236	2.137591	0.0170236	0.4080149	105	up	*
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	0.0168550	2.135433	0.0168550	0.4080149	140	up	*
GO:0032103	positive regulation of response to external stimulus	0.0168999	2.134958	0.0168999	0.4080149	125	up	*
GO:0002437	inflammatory response to antigenic stimulus	0.0188725	2.134918	0.0188725	0.4105554	27	up	*
GO:0002438	acute inflammatory response to antigenic stimulus	0.0228174	2.131758	0.0228174	0.4268051	11	up	*
GO:0003002	regionalization	0.0170295	2.126503	0.0170295	0.4080149	214	up	*
GO:0055123	digestive system development	0.0176823	2.121692	0.0176823	0.4105554	90	up	*
GO:0070482	response to oxygen levels	0.0173749	2.118835	0.0173749	0.4105554	206	up	*
GO:0060326	cell chemotaxis	0.0177863	2.114427	0.0177863	0.4105554	127	up	*
GO:0008528	G-protein coupled peptide receptor activity	0.0183541	2.111462	0.0183541	0.4105554	64	up	*
GO:0046058	cAMP metabolic process	0.0183796	2.107741	0.0183796	0.4105554	75	up	*
GO:0042403	thyroid hormone metabolic process	0.0223841	2.106087	0.0223841	0.4268051	17	up	*
GO:0000779	condensed chromosome, centromeric region	0.0185780	2.101978	0.0185780	0.4105554	80	up	*
GO:0042303	molting cycle	0.0188649	2.098931	0.0188649	0.4105554	73	up	*
GO:0042633	hair cycle	0.0188649	2.098931	0.0188649	0.4105554	73	up	*
GO:0031644	regulation of neurological system process	0.0185117	2.095703	0.0185117	0.4105554	159	up	*
GO:2000147	positive regulation of cell motility	0.0184909	2.093091	0.0184909	0.4105554	205	up	*
GO:0030003	cellular cation homeostasis	0.0184787	2.091636	0.0184787	0.4105554	285	up	*
GO:0046879	hormone secretion	0.0187434	2.090327	0.0187434	0.4105554	162	up	*
GO:0048568	embryonic organ development	0.0186047	2.088991	0.0186047	0.4105554	259	up	*
GO:0001763	morphogenesis of a branching structure	0.0188034	2.088045	0.0188034	0.4105554	159	up	*
GO:0003156	regulation of organ formation	0.0219676	2.086113	0.0219676	0.4268051	25	up	*
GO:0001708	cell fate specification	0.0207250	2.085735	0.0207250	0.4268051	40	up	*
GO:0009914	hormone transport	0.0190494	2.083392	0.0190494	0.4126852	165	up	*
GO:0001653	peptide receptor activity	0.0196124	2.083182	0.0196124	0.4213831	65	up	*
GO:0007276	gamete generation	0.0188367	2.082698	0.0188367	0.4105554	338	up	*
GO:0010669	epithelial structure maintenance	0.0269493	2.080943	0.0269493	0.4527322	11	up	*
GO:0030335	positive regulation of cell migration	0.0192119	2.077486	0.0192119	0.4144840	200	up	*
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	0.0243452	2.072127	0.0243452	0.4413417	14	up	*
GO:0015370	solute:sodium symporter activity	0.0226346	2.071372	0.0226346	0.4268051	30	up	*
GO:0072089	stem cell proliferation	0.0265600	2.069837	0.0265600	0.4523966	16	up	*
GO:0008324	cation transmembrane transporter activity	0.0197177	2.062956	0.0197177	0.4219102	423	up	*
GO:0007052	mitotic spindle organization	0.0217662	2.062931	0.0217662	0.4268051	32	up	*
GO:0007420	brain development	0.0198966	2.059708	0.0198966	0.4228719	381	up	*
GO:0005930	axoneme	0.0207999	2.059515	0.0207999	0.4268051	62	up	*
GO:0061351	neural precursor cell proliferation	0.0210408	2.059319	0.0210408	0.4268051	72	up	*
GO:0034358	plasma lipoprotein particle	0.0241492	2.058679	0.0241492	0.4408501	22	up	*
GO:0002443	leukocyte mediated immunity	0.0201934	2.058548	0.0201934	0.4228719	163	up	*
GO:0002861	regulation of inflammatory response to antigenic stimulus	0.0241321	2.056234	0.0241321	0.4408501	17	up	*
GO:0009880	embryonic pattern specification	0.0216076	2.055805	0.0216076	0.4268051	46	up	*
GO:0048663	neuron fate commitment	0.0229095	2.055706	0.0229095	0.4268051	29	up	*
GO:0050804	regulation of synaptic transmission	0.0205516	2.053944	0.0205516	0.4268051	136	up	*
GO:0045596	negative regulation of cell differentiation	0.0202288	2.053404	0.0202288	0.4228719	345	up	*
GO:0019953	sexual reproduction	0.0202486	2.052219	0.0202486	0.4228719	392	up	*
GO:0060675	ureteric bud morphogenesis	0.0216713	2.050204	0.0216713	0.4268051	47	up	*
GO:0001608	G-protein coupled nucleotide receptor activity	0.0254562	2.043183	0.0254562	0.4446993	18	up	*
GO:0045028	G-protein coupled purinergic nucleotide receptor activity	0.0254562	2.043183	0.0254562	0.4446993	18	up	*
GO:0007423	sensory organ development	0.0208104	2.041367	0.0208104	0.4268051	325	up	*
GO:0048333	mesodermal cell differentiation	0.0269680	2.037636	0.0269680	0.4527322	19	up	*
GO:0015849	organic acid transport	0.0214674	2.032558	0.0214674	0.4268051	163	up	*
GO:0046942	carboxylic acid transport	0.0214674	2.032558	0.0214674	0.4268051	163	up	*
GO:0061029	eyelid development in camera-type eye	0.0299706	2.031586	0.0299706	0.4668472	10	up	*
GO:0044708	single-organism behavior	0.0214497	2.029991	0.0214497	0.4268051	261	up	*
GO:0032526	response to retinoic acid	0.0224909	2.029156	0.0224909	0.4268051	71	up	*
GO:0007492	endoderm development	0.0236836	2.026350	0.0236836	0.4369328	45	up	*
GO:0051241	negative regulation of multicellular organismal process	0.0216593	2.025537	0.0216593	0.4268051	279	up	*
GO:0040017	positive regulation of locomotion	0.0219311	2.021705	0.0219311	0.4268051	211	up	*
GO:0036293	response to decreased oxygen levels	0.0220726	2.019857	0.0220726	0.4268051	194	up	*
GO:0001501	skeletal system development	0.0219740	2.019257	0.0219740	0.4268051	294	up	*
GO:0050714	positive regulation of protein secretion	0.0229536	2.017415	0.0229536	0.4268051	69	up	*
GO:0001942	hair follicle development	0.0229711	2.016746	0.0229711	0.4268051	67	up	*
GO:0022404	molting cycle process	0.0229711	2.016746	0.0229711	0.4268051	67	up	*
GO:0022405	hair cycle process	0.0229711	2.016746	0.0229711	0.4268051	67	up	*
GO:0051272	positive regulation of cellular component movement	0.0224839	2.011176	0.0224839	0.4268051	211	up	*
GO:2000027	regulation of organ morphogenesis	0.0227746	2.011138	0.0227746	0.4268051	116	up	*
GO:0044711	single-organism biosynthetic process	0.0224355	2.009301	0.0224355	0.4268051	382	up	*
GO:0048730	epidermis morphogenesis	0.0251727	2.005946	0.0251727	0.4446993	29	up	*
GO:0044283	small molecule biosynthetic process	0.0227196	2.004057	0.0227196	0.4268051	375	up	*
GO:0001666	response to hypoxia	0.0229168	2.004006	0.0229168	0.4268051	192	up	*
GO:0060485	mesenchyme development	0.0233576	1.999139	0.0233576	0.4324467	135	up	*
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	0.0291797	1.996395	0.0291797	0.4658938	16	up	*
GO:0019198	transmembrane receptor protein phosphatase activity	0.0291797	1.996395	0.0291797	0.4658938	16	up	*
GO:0015698	inorganic anion transport	0.0247735	1.996036	0.0247735	0.4444766	42	up	*
GO:0030286	dynein complex	0.0253103	1.993030	0.0253103	0.4446993	34	up	*
GO:0008301	DNA binding, bending	0.0264653	1.985551	0.0264653	0.4523966	36	up	*
GO:0008202	steroid metabolic process	0.0240384	1.983063	0.0240384	0.4408501	199	up	*
GO:0044706	multi-multicellular organism process	0.0244387	1.979839	0.0244387	0.4415026	139	up	*
GO:0051707	response to other organism	0.0242758	1.975621	0.0242758	0.4413417	424	up	*
GO:0001658	branching involved in ureteric bud morphogenesis	0.0260108	1.972879	0.0260108	0.4501277	43	up	*
GO:0050954	sensory perception of mechanical stimulus	0.0250468	1.971998	0.0250468	0.4446993	106	up	*
GO:0048598	embryonic morphogenesis	0.0246340	1.969700	0.0246340	0.4434972	379	up	*
GO:0030246	carbohydrate binding	0.0249313	1.968280	0.0249313	0.4446993	168	up	*
GO:0007611	learning or memory	0.0252779	1.966397	0.0252779	0.4446993	123	up	*
GO:0032994	protein-lipid complex	0.0291051	1.965442	0.0291051	0.4658938	23	up	*
GO:0048704	embryonic skeletal system morphogenesis	0.0261849	1.960173	0.0261849	0.4511933	62	up	*
GO:0000777	condensed chromosome kinetochore	0.0260171	1.958557	0.0260171	0.4501277	76	up	*
GO:0048706	embryonic skeletal system development	0.0260369	1.957753	0.0260369	0.4501277	82	up	*
GO:0004857	enzyme inhibitor activity	0.0254674	1.957627	0.0254674	0.4446993	222	up	*
GO:0003014	renal system process	0.0266014	1.955990	0.0266014	0.4523966	53	up	*
GO:0002064	epithelial cell development	0.0265552	1.955159	0.0265552	0.4523966	66	up	*
GO:0015294	solute:cation symporter activity	0.0271444	1.953767	0.0271444	0.4527829	55	up	*
GO:0005227	calcium activated cation channel activity	0.0298442	1.950064	0.0298442	0.4668472	18	up	*
GO:0050715	positive regulation of cytokine secretion	0.0275376	1.948694	0.0275376	0.4535457	46	up	*
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	0.0336716	1.947734	0.0336716	0.4924350	10	up	*
GO:0010744	positive regulation of macrophage derived foam cell differentiation	0.0328325	1.946344	0.0328325	0.4911706	12	up	*
GO:0008076	voltage-gated potassium channel complex	0.0274998	1.943150	0.0274998	0.4535457	48	up	*
GO:0034705	potassium channel complex	0.0274998	1.943150	0.0274998	0.4535457	48	up	*
GO:0055088	lipid homeostasis	0.0274521	1.940105	0.0274521	0.4535457	64	up	*
GO:0051048	negative regulation of secretion	0.0271128	1.938655	0.0271128	0.4527829	87	up	*
GO:0045202	synapse	0.0267780	1.933741	0.0267780	0.4527322	355	up	*
GO:0030334	regulation of cell migration	0.0268087	1.933261	0.0268087	0.4527322	344	up	*
GO:0000940	condensed chromosome outer kinetochore	0.0342282	1.932202	0.0342282	0.4928912	11	up	*
GO:0050891	multicellular organismal water homeostasis	0.0336544	1.930697	0.0336544	0.4924350	12	up	*
GO:0042035	regulation of cytokine biosynthetic process	0.0281686	1.927515	0.0281686	0.4581564	71	up	*
GO:0002009	morphogenesis of an epithelium	0.0276300	1.920387	0.0276300	0.4536365	319	up	*
GO:0005244	voltage-gated ion channel activity	0.0280813	1.919300	0.0280813	0.4581564	118	up	*
GO:0022832	voltage-gated channel activity	0.0280813	1.919300	0.0280813	0.4581564	118	up	*
GO:0005231	excitatory extracellular ligand-gated ion channel activity	0.0301435	1.918402	0.0301435	0.4670006	34	up	*
GO:0045095	keratin filament	0.0353135	1.918268	0.0353135	0.4928912	14	up	*
GO:0005200	structural constituent of cytoskeleton	0.0294056	1.915858	0.0294056	0.4667624	49	up	*
GO:0002449	lymphocyte mediated immunity	0.0286472	1.910241	0.0286472	0.4616269	129	up	*
GO:0097110	scaffold protein binding	0.0329481	1.907370	0.0329481	0.4914911	20	up	*
GO:0009607	response to biotic stimulus	0.0284140	1.907304	0.0284140	0.4607135	447	up	*
GO:0043565	sequence-specific DNA binding	0.0285881	1.904635	0.0285881	0.4616269	439	up	*
GO:0007088	regulation of mitosis	0.0295023	1.903158	0.0295023	0.4667624	83	up	*
GO:0051783	regulation of nuclear division	0.0295023	1.903158	0.0295023	0.4667624	83	up	*
GO:0007422	peripheral nervous system development	0.0300442	1.901658	0.0300442	0.4668472	56	up	*
GO:0001158	enhancer sequence-specific DNA binding	0.0335827	1.900988	0.0335827	0.4924350	17	up	*
GO:0006171	cAMP biosynthetic process	0.0300163	1.898831	0.0300163	0.4668472	60	up	*
GO:0015269	calcium-activated potassium channel activity	0.0349126	1.895823	0.0349126	0.4928912	14	up	*
GO:0010389	regulation of G2/M transition of mitotic cell cycle	0.0334141	1.895236	0.0334141	0.4924350	26	up	*
GO:0060487	lung epithelial cell differentiation	0.0351940	1.892842	0.0351940	0.4928912	16	up	*
GO:0072376	protein activation cascade	0.0309710	1.892188	0.0309710	0.4732444	48	up	*
GO:0031406	carboxylic acid binding	0.0299119	1.891149	0.0299119	0.4668472	134	up	*
GO:0060900	embryonic camera-type eye formation	0.0386800	1.890582	0.0386800	0.5028074	10	up	*
GO:0038024	cargo receptor activity	0.0306454	1.890391	0.0306454	0.4717000	57	up	*
GO:0097060	synaptic membrane	0.0298951	1.889565	0.0298951	0.4668472	154	up	*
GO:0021536	diencephalon development	0.0325120	1.882937	0.0325120	0.4891790	44	up	*
GO:0014031	mesenchymal cell development	0.0309997	1.877709	0.0309997	0.4732444	107	up	*
GO:0032421	stereocilium bundle	0.0340363	1.875645	0.0340363	0.4928912	25	up	*
GO:0043269	regulation of ion transport	0.0307179	1.875302	0.0307179	0.4717000	214	up	*
GO:0000076	DNA replication checkpoint	0.0390166	1.874755	0.0390166	0.5028074	10	up	*
GO:0010564	regulation of cell cycle process	0.0306634	1.873999	0.0306634	0.4717000	391	up	*
GO:0045840	positive regulation of mitosis	0.0348217	1.870733	0.0348217	0.4928912	26	up	*
GO:0051785	positive regulation of nuclear division	0.0348217	1.870733	0.0348217	0.4928912	26	up	*
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	0.0358741	1.868852	0.0358741	0.4928912	16	up	*
GO:0060541	respiratory system development	0.0314066	1.867718	0.0314066	0.4780583	155	up	*
GO:0009988	cell-cell recognition	0.0368731	1.866286	0.0368731	0.4972828	16	up	*
GO:0048754	branching morphogenesis of an epithelial tube	0.0316984	1.864577	0.0316984	0.4797017	129	up	*
GO:0051969	regulation of transmission of nerve impulse	0.0316808	1.864411	0.0316808	0.4797017	153	up	*
GO:0010717	regulation of epithelial to mesenchymal transition	0.0331692	1.861750	0.0331692	0.4921424	41	up	*
GO:0009913	epidermal cell differentiation	0.0327663	1.857069	0.0327663	0.4911706	74	up	*
GO:0000087	M phase of mitotic cell cycle	0.0320914	1.854116	0.0320914	0.4842461	338	up	*
GO:0004970	ionotropic glutamate receptor activity	0.0400628	1.853352	0.0400628	0.5028074	14	up	*
GO:0050710	negative regulation of cytokine secretion	0.0373367	1.850947	0.0373367	0.4972828	16	up	*
GO:0001871	pattern binding	0.0377986	1.850796	0.0377986	0.4987334	14	up	*
GO:0030247	polysaccharide binding	0.0377986	1.850796	0.0377986	0.4987334	14	up	*
GO:0055067	monovalent inorganic cation homeostasis	0.0338457	1.850171	0.0338457	0.4928912	53	up	*
GO:0061041	regulation of wound healing	0.0334459	1.849075	0.0334459	0.4924350	68	up	*
GO:0006958	complement activation, classical pathway	0.0352003	1.848822	0.0352003	0.4928912	31	up	*
GO:0071599	otic vesicle development	0.0395009	1.847776	0.0395009	0.5028074	14	up	*
GO:0008217	regulation of blood pressure	0.0331803	1.846839	0.0331803	0.4921424	94	up	*
GO:0071391	cellular response to estrogen stimulus	0.0388515	1.846224	0.0388515	0.5028074	13	up	*
GO:0044447	axoneme part	0.0358204	1.839173	0.0358204	0.4928912	28	up	*
GO:0005903	brush border	0.0355199	1.838148	0.0355199	0.4928912	39	up	*
GO:0048645	organ formation	0.0354310	1.837065	0.0354310	0.4928912	37	up	*
GO:0001759	organ induction	0.0398338	1.834565	0.0398338	0.5028074	16	up	*
GO:0006590	thyroid hormone generation	0.0407907	1.832032	0.0407907	0.5046641	14	up	*
GO:0031589	cell-substrate adhesion	0.0339427	1.831089	0.0339427	0.4928912	200	up	*
GO:0003007	heart morphogenesis	0.0344531	1.825834	0.0344531	0.4928912	149	up	*
GO:0042310	vasoconstriction	0.0367041	1.822521	0.0367041	0.4972828	42	up	*
GO:0050708	regulation of protein secretion	0.0352322	1.820457	0.0352322	0.4928912	95	up	*
GO:0006641	triglyceride metabolic process	0.0356061	1.819940	0.0356061	0.4928912	76	up	*
GO:0051302	regulation of cell division	0.0355762	1.819712	0.0355762	0.4928912	74	up	*
GO:0048167	regulation of synaptic plasticity	0.0357604	1.816214	0.0357604	0.4928912	78	up	*
GO:0048762	mesenchymal cell differentiation	0.0354684	1.815330	0.0354684	0.4928912	117	up	*
GO:0048332	mesoderm morphogenesis	0.0369052	1.814889	0.0369052	0.4972828	51	up	*
GO:0034364	high-density lipoprotein particle	0.0455881	1.813993	0.0455881	0.5120846	12	up	*
GO:0071241	cellular response to inorganic substance	0.0362388	1.811290	0.0362388	0.4965951	65	up	*
GO:0016053	organic acid biosynthetic process	0.0353819	1.811128	0.0353819	0.4928912	246	up	*
GO:0046394	carboxylic acid biosynthetic process	0.0353819	1.811128	0.0353819	0.4928912	246	up	*
GO:0030324	lung development	0.0358413	1.808438	0.0358413	0.4928912	139	up	*
GO:0021983	pituitary gland development	0.0395716	1.808290	0.0395716	0.5028074	28	up	*
GO:0005504	fatty acid binding	0.0396451	1.808221	0.0396451	0.5028074	21	up	*
GO:0051592	response to calcium ion	0.0366047	1.807328	0.0366047	0.4972828	71	up	*
GO:0051781	positive regulation of cell division	0.0372965	1.806442	0.0372965	0.4972828	50	up	*
GO:0090183	regulation of kidney development	0.0376236	1.805774	0.0376236	0.4987334	38	up	*
GO:0090102	cochlea development	0.0392007	1.805732	0.0392007	0.5028074	26	up	*
GO:0008608	attachment of spindle microtubules to kinetochore	0.0403213	1.802879	0.0403213	0.5036298	18	up	*
GO:0044070	regulation of anion transport	0.0381245	1.802866	0.0381245	0.5001205	36	up	*
GO:0071837	HMG box domain binding	0.0433603	1.801712	0.0433603	0.5098963	11	up	*
GO:0007162	negative regulation of cell adhesion	0.0369658	1.800237	0.0369658	0.4972828	74	up	*
GO:0045137	development of primary sexual characteristics	0.0364777	1.800003	0.0364777	0.4972828	160	up	*
GO:0042611	MHC protein complex	0.0425369	1.797401	0.0425369	0.5098963	16	up	*
GO:0044089	positive regulation of cellular component biogenesis	0.0416664	1.796009	0.0416664	0.5082717	15	up	*
GO:0030817	regulation of cAMP biosynthetic process	0.0378277	1.793728	0.0378277	0.4987334	55	up	*
GO:0060343	trabecula formation	0.0409508	1.788573	0.0409508	0.5054469	21	up	*
GO:0035239	tube morphogenesis	0.0372697	1.787093	0.0372697	0.4972828	249	up	*
GO:0000280	nuclear division	0.0373351	1.785489	0.0373351	0.4972828	328	up	*
GO:0007067	mitosis	0.0373351	1.785489	0.0373351	0.4972828	328	up	*
GO:0005234	extracellular-glutamate-gated ion channel activity	0.0448222	1.784696	0.0448222	0.5120846	15	up	*
GO:0045747	positive regulation of Notch signaling pathway	0.0451382	1.784336	0.0451382	0.5120846	15	up	*
GO:0019935	cyclic-nucleotide-mediated signaling	0.0402343	1.781832	0.0402343	0.5036298	28	up	*
GO:0050890	cognition	0.0380647	1.781661	0.0380647	0.5001205	131	up	*
GO:0022843	voltage-gated cation channel activity	0.0383807	1.780489	0.0383807	0.5022201	87	up	*
GO:0055024	regulation of cardiac muscle tissue development	0.0405731	1.777302	0.0405731	0.5046641	33	up	*
GO:0045111	intermediate filament cytoskeleton	0.0388804	1.775795	0.0388804	0.5028074	86	up	*
GO:0032355	response to estradiol stimulus	0.0395333	1.775528	0.0395333	0.5028074	60	up	*
GO:0046209	nitric oxide metabolic process	0.0400348	1.772525	0.0400348	0.5028074	53	up	*
GO:0030323	respiratory tube development	0.0387770	1.771832	0.0387770	0.5028074	142	up	*
GO:0042359	vitamin D metabolic process	0.0460553	1.770186	0.0460553	0.5120846	12	up	*
GO:0051222	positive regulation of protein transport	0.0390693	1.768084	0.0390693	0.5028074	148	up	*
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	0.0465307	1.767921	0.0465307	0.5136080	11	up	*
GO:0001614	purinergic nucleotide receptor activity	0.0427835	1.765382	0.0427835	0.5098963	24	up	*
GO:0016502	nucleotide receptor activity	0.0427835	1.765382	0.0427835	0.5098963	24	up	*
GO:0048593	camera-type eye morphogenesis	0.0400499	1.764469	0.0400499	0.5028074	69	up	*
GO:0048705	skeletal system morphogenesis	0.0394371	1.763710	0.0394371	0.5028074	142	up	*
GO:0030169	low-density lipoprotein particle binding	0.0451473	1.760814	0.0451473	0.5120846	14	up	*
GO:0030814	regulation of cAMP metabolic process	0.0407299	1.758410	0.0407299	0.5046641	56	up	*
GO:0045833	negative regulation of lipid metabolic process	0.0415640	1.755743	0.0415640	0.5082102	43	up	*
GO:0008188	neuropeptide receptor activity	0.0473939	1.755066	0.0473939	0.5155076	11	up	*
GO:0000279	M phase	0.0400024	1.752638	0.0400024	0.5028074	463	up	*
GO:0008066	glutamate receptor activity	0.0460261	1.751863	0.0460261	0.5120846	18	up	*
GO:0030879	mammary gland development	0.0406976	1.750820	0.0406976	0.5046641	110	up	*
GO:0071248	cellular response to metal ion	0.0414632	1.748810	0.0414632	0.5081673	61	up	*
GO:0050728	negative regulation of inflammatory response	0.0421507	1.744289	0.0421507	0.5098963	55	up	*
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	0.0412921	1.742198	0.0412921	0.5081673	148	up	*
GO:0009612	response to mechanical stimulus	0.0414394	1.741932	0.0414394	0.5081673	118	up	*
GO:0060479	lung cell differentiation	0.0469172	1.739548	0.0469172	0.5148571	17	up	*
GO:0015850	organic hydroxy compound transport	0.0422723	1.735986	0.0422723	0.5098963	87	up	*
GO:0015079	potassium ion transmembrane transporter activity	0.0422119	1.735731	0.0422119	0.5098963	86	up	*
GO:0042107	cytokine metabolic process	0.0426311	1.733203	0.0426311	0.5098963	82	up	*
GO:0009582	detection of abiotic stimulus	0.0429953	1.732170	0.0429953	0.5098963	61	up	*
GO:0001570	vasculogenesis	0.0430197	1.731305	0.0430197	0.5098963	60	up	*
GO:0042542	response to hydrogen peroxide	0.0428337	1.730721	0.0428337	0.5098963	78	up	*
GO:0060325	face morphogenesis	0.0455795	1.730388	0.0455795	0.5120846	27	up	*
GO:0007498	mesoderm development	0.0431328	1.729856	0.0431328	0.5098963	79	up	*
GO:0045777	positive regulation of blood pressure	0.0461361	1.727486	0.0461361	0.5120846	20	up	*
GO:0006639	acylglycerol metabolic process	0.0433447	1.726163	0.0433447	0.5098963	80	up	*
GO:0002089	lens morphogenesis in camera-type eye	0.0481375	1.725143	0.0481375	0.5171311	17	up	*
GO:0030802	regulation of cyclic nucleotide biosynthetic process	0.0435792	1.724262	0.0435792	0.5104841	63	up	*
GO:0021510	spinal cord development	0.0445238	1.723234	0.0445238	0.5120846	42	up	*
GO:0050818	regulation of coagulation	0.0440735	1.723188	0.0440735	0.5120846	55	up	*
GO:0046546	development of primary male sexual characteristics	0.0436077	1.723037	0.0436077	0.5104841	83	up	*
GO:0003073	regulation of systemic arterial blood pressure	0.0444121	1.721137	0.0444121	0.5120846	44	up	*
GO:0016064	immunoglobulin mediated immune response	0.0437285	1.720593	0.0437285	0.5107528	81	up	*
GO:0045211	postsynaptic membrane	0.0433622	1.719727	0.0433622	0.5098963	131	up	*
GO:0032838	cell projection cytoplasm	0.0442081	1.719382	0.0442081	0.5120846	56	up	*
GO:0009084	glutamine family amino acid biosynthetic process	0.0482744	1.715602	0.0482744	0.5175368	16	up	*
GO:0006935	chemotaxis	0.0433461	1.714887	0.0433461	0.5098963	478	up	*
GO:0042330	taxis	0.0433461	1.714887	0.0433461	0.5098963	478	up	*
GO:0031100	organ regeneration	0.0458832	1.712046	0.0458832	0.5120846	33	up	*
GO:0003205	cardiac chamber development	0.0443885	1.711167	0.0443885	0.5120846	92	up	*
GO:0001704	formation of primary germ layer	0.0452431	1.710956	0.0452431	0.5120846	64	up	*
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	0.0476477	1.710721	0.0476477	0.5161180	20	up	*
GO:0045931	positive regulation of mitotic cell cycle	0.0461810	1.708048	0.0461810	0.5120846	34	up	*
GO:0006879	cellular iron ion homeostasis	0.0457325	1.707897	0.0457325	0.5120846	56	up	*
GO:0005902	microvillus	0.0456654	1.706104	0.0456654	0.5120846	53	up	*
GO:0001505	regulation of neurotransmitter levels	0.0450162	1.704708	0.0450162	0.5120846	101	up	*
GO:0001822	kidney development	0.0447583	1.703120	0.0447583	0.5120846	167	up	*
GO:0060042	retina morphogenesis in camera-type eye	0.0480367	1.703001	0.0480367	0.5171131	27	up	*
GO:0019932	second-messenger-mediated signaling	0.0450568	1.701746	0.0450568	0.5120846	120	up	*
GO:0045682	regulation of epidermis development	0.0471407	1.700522	0.0471407	0.5148987	32	up	*
GO:0042311	vasodilation	0.0470890	1.698717	0.0470890	0.5148987	43	up	*
GO:0006638	neutral lipid metabolic process	0.0461465	1.695712	0.0461465	0.5120846	81	up	*
GO:0051480	cytosolic calcium ion homeostasis	0.0456408	1.694848	0.0456408	0.5120846	139	up	*
GO:0033555	multicellular organismal response to stress	0.0473658	1.692262	0.0473658	0.5155076	41	up	*
GO:0010001	glial cell differentiation	0.0464350	1.689204	0.0464350	0.5136080	110	up	*
GO:0045926	negative regulation of growth	0.0461965	1.688614	0.0461965	0.5120846	157	up	*
GO:0042089	cytokine biosynthetic process	0.0469397	1.687306	0.0469397	0.5148571	79	up	*
GO:0015908	fatty acid transport	0.0475829	1.686478	0.0475829	0.5161180	51	up	*
GO:0043588	skin development	0.0480244	1.685385	0.0480244	0.5171131	41	up	*
GO:0006813	potassium ion transport	0.0468915	1.684682	0.0468915	0.5148571	91	up	*
GO:0033293	monocarboxylic acid binding	0.0496415	1.676345	0.0496415	0.5260423	33	up	*
GO:0006694	steroid biosynthetic process	0.0479003	1.673350	0.0479003	0.5171131	108	up	*
GO:0030808	regulation of nucleotide biosynthetic process	0.0487948	1.668698	0.0487948	0.5188547	66	up	*
GO:1900371	regulation of purine nucleotide biosynthetic process	0.0487948	1.668698	0.0487948	0.5188547	66	up	*
GO:0006898	receptor-mediated endocytosis	0.0484932	1.667415	0.0484932	0.5188171	109	up	*
GO:0060562	epithelial tube morphogenesis	0.0486187	1.661702	0.0486187	0.5188547	238	up	*
GO:0002706	regulation of lymphocyte mediated immunity	0.0498085	1.660718	0.0498085	0.5264169	58	up	*
GO:0048634	regulation of muscle organ development	0.0496723	1.656957	0.0496723	0.5260423	94	up	*

Associations of MHC-II related genes with SILA

Compare MHC-II related genes I vs A

Using VST normed genes

Using TPM normed genes

Using FPKM normed genes

PCA of patients using MHC-II related genes

Using VST normed genes

Using TPM normed genes

Using FPKM normed genes

Compare MHC-II related genes I vs A

Using VST normed genes

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

Symbol	Gene	Median.Ind	Median.Agg	p.value	p.adjusted
HLA-B	ENSG00000223532.5	5.5230143194896	11.307984604401	0.00403916387406532	0.0363525
HLA-DQA1	ENSG00000196735.7	12.6569035726553	11.4195419797818	0.0518707877577961	0.2326642
HLA-DRB1	ENSG00000196126.6	12.9080576130221	11.4704118444961	0.0775547463551605	0.2326642

Symbol	Gene	Median.Ind	Median.Agg	p.value	p.adjusted
HLA-B	ENSG00000223532.5	5.5230143194896	11.307984604401	0.00403916387406532	0.0080783

Using TPM normed genes

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

Symbol	Gene	Median.Ind	Median.Agg	p.value	p.adjusted
HLA-B	ENSG00000223532.5	0.908155215644466	55.2343472509793	0.00588585966231203	0.0529727
HLA-DQA1	ENSG00000196735.7	67.8480458367615	20.7860294086988	0.0267135296089953	0.1202109
HLA-DRB1	ENSG00000196126.6	465.419500480767	151.77617621223	0.0431981807566885	0.1295945

Symbol	Gene	Median.Ind	Median.Agg	p.value	p.adjusted
HLA-B	ENSG00000223532.5	0.908155215644466	55.2343472509793	0.00588585966231203	0.0117717

Using FPKM normed genes

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

Symbol	Gene	Median.Ind	Median.Agg	p.value	p.adjusted
HLA-B	ENSG00000223532.5	0.4495	29.272	0.00319305944396607	0.0287375
HLA-DQA1	ENSG00000196735.7	32.2645	11.4345	0.0431981807566885	0.1665480
HLA-DRB1	ENSG00000196126.6	212.778	72.885	0.0555159990509268	0.1665480

## Warning in wilcox.test.default(mat[ind, i], mat[-ind, i]): cannot compute exact
## p-value with ties

Symbol	Gene	Median.Ind	Median.Agg	p.value	p.adjusted
HLA-B	ENSG00000223532.5	0.4495	29.272	0.00319305944396607	0.0063861

Transcription Factor activiy (VIPER)

For documentation click here https://bioconductor.org/packages/release/bioc/vignettes/viper/inst/doc/viper.pdf

Comparing two groups with msVIPER

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VIPER plot showing the projection of the negative (repressed, shown in blue color) and positive (activated, shown in red color) targets for each TF, as inferred by ARACNe and correlation analysis when reverse engineering the regulatory network (vertical lines resembling a bar-code), on the GES (x-axis), where the genes in the GES were rank-sorted from the one most down-regulated to the one most upregulated in the ‘test’ vs ‘reference’ conditions. The optional two-columns heatmap displayed on the right side of the figure shows the inferred differential activity (first column) and differential expression (second column), with the rank of the displayed genes in the GES (shown all the way to the right).

	Regulon	Size	NES	p.value	FDR
FOXM1	FOXM1	32	1.39	0.16500	0.702
E2F1	E2F1	294	1.35	0.17700	0.702
FOXO3	FOXO3	36	-1.32	0.18600	0.702
ELK1	ELK1	28	-1.36	0.17200	0.702
SP1	SP1	259	-1.43	0.15300	0.702
FOS	FOS	74	-1.58	0.11500	0.702
GATA2	GATA2	32	-1.65	0.09950	0.702
USF2	USF2	29	-1.69	0.09170	0.702
SPI1	SPI1	81	-2.50	0.01230	0.264
FOXO1	FOXO1	34	-2.78	0.00541	0.233

Leading-edge analysis

To identify the genes driving the enrichment of a gene-set on a gene expression signature (GES) based on Gene Set Enrichment Analysis (GSEA).

	Regulon	Size	NES	p.value	FDR	Ledge
FOXM1	FOXM1	32	1.39	0.16500	0.702	CENPF, CCNB1, CDC25A, ONECUT1, + 10 genes
E2F1	E2F1	294	1.35	0.17700	0.702	CDCA7, HELLS, PCSK6, BDH1, + 93 genes
FOXO3	FOXO3	36	-1.32	0.18600	0.702	SIRT1, TXNIP, DUSP6, HBP1, + 10 genes
ELK1	ELK1	28	-1.36	0.17200	0.702	FOSL1, LY96, FOS, PSEN1, + 7 genes
SP1	SP1	259	-1.43	0.15300	0.702	BSG, DCK, TPMT, CTSL, + 68 genes
FOS	FOS	74	-1.58	0.11500	0.702	SP3, FOSL1, NOS1, NFATC1, + 13 genes
GATA2	GATA2	32	-1.65	0.09950	0.702	CCM2, PPP1R15A, DPYSL2, ARRDC4, + 5 genes
USF2	USF2	29	-1.69	0.09170	0.702	SF1, THBS1, CYP19A1, TGFB2, + 6 genes
SPI1	SPI1	81	-2.50	0.01230	0.264	PTGIR, CSF1, TBXAS1, BCL6, + 46 genes
FOXO1	FOXO1	34	-2.78	0.00541	0.233	CDKN2B, CDKN1B, CNR1, MCM5, + 12 genes

Deconvolution Results

XCell

## Warning in wilcox.test.default(c(0, 0, 0, 0.0148, 0, 0.0106, 0, 0, 0, 0.0046:
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.0148, 0, 0.0106, 0, 0, 0, 0.0046:
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0062, 0, 0, 0, 0.0033, 0, 0.0027, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0014, 0, 0, 0.1452, 0, 0, 0, 0, 0.0413:
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0014, 0, 0, 0.1452, 0, 0, 0, 0, 0.0413:
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.1, 0.0208, 0, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.047, 0.3325, 0, 0.008, 0, 0.7011, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.047, 0.3325, 0, 0.008, 0, 0.7011, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.1244, 0, 0.1337, 0.0027, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0214, 0.0684, 0, 0, 0.0094, 0.0816, 0.1816, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0214, 0.0684, 0, 0, 0.0094, 0.0816, 0.1816, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0432, 0.0046, 0.0073, 0, 0.0072, 0.1808, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0162, 0.0216, 0, 0, 0, 0.1458, 0.0464, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0162, 0.0216, 0, 0, 0, 0.1458, 0.0464, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0.0124, 0.003, 0, 0.0048, 0.0452, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0462, 0.0199, 0.0679, 0, 0.0132, 0, 0.0849, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0462, 0.0199, 0.0679, 0, 0.0132, 0, 0.0849, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0539, 0.0317, 0.0367, 0.0138, 0, 0.0144, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0444, 0.1224, 0.0231, 0, 0.0289, 0, 0.1765, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0444, 0.1224, 0.0231, 0, 0.0289, 0, 0.1765, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0823, 0.0105, 0.0285, 0.0397, 0.0174, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0645, 0.0708, 0, 0.0107, 0, 0.3989, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0645, 0.0708, 0, 0.0107, 0, 0.3989, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0179, 0.0116, 0.0438, 0.0134, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0979, 0.0715, 0.0074, 0.0529, 0.003, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0979, 0.0715, 0.0074, 0.0529, 0.003, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.004, 0, 0.0707, 0, 0.0468, 0.0922, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.1136, 0.0612, 0, 0.0182, 0, 0.2938, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.1136, 0.0612, 0, 0.0182, 0, 0.2938, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0299, 0, 0.0293, 0.0042, 0.0326, 0.0499, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.1205, 0.059, 0, 0, 0, 0.3162, 0.0364, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.1205, 0.059, 0, 0, 0, 0.3162, 0.0364, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0147, 0, 0.0436, 0, 0.0452, 0.0128, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0536, 0, 0, 0, 0, 0.0568, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0536, 0, 0, 0, 0, 0.0568, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0148, 0, 0, 0, 0, 0.0084, 0, 0.0057, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0241, 0.0185, 0, 0.0016, 0, 0.1114, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0241, 0.0185, 0, 0.0016, 0, 0.1114, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(3e-04, 0, 0, 0.0307, 0, 0.0024, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0082, 0.0382, 0.0118, 0.0023, 0.002, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0082, 0.0382, 0.0118, 0.0023, 0.002, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0036, 0.0082, 0.0067, 0.0424, 0.0107, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.0099, 0.0093, 0.0112, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.0099, 0.0093, 0.0112, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0078, 0, 0.002, 0.0088, 7e-04, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0465, 0.0375, 0.1193, 0.062, 0.1813, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0465, 0.0375, 0.1193, 0.062, 0.1813, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.1219, 0, 0, 0.0835, 0.0913, 0.1353, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0305, 0.0627, 0.17, 0, 0.0113, 0, 0.264, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0305, 0.0627, 0.17, 0, 0.0113, 0, 0.264, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0346, 0.0136, 0.1095, 0, 0.0743, 0.031, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0325, 0.0112, 0.0092, 0, 0.0215, 0, 0.0493, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0325, 0.0112, 0.0092, 0, 0.0215, 0, 0.0493, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.004, 5e-04, 0.0078, 0.002, 0.0472, 0.0053, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0674, 0.0211, 0.0657, 0.312, 0.1087, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0674, 0.0211, 0.0657, 0.312, 0.1087, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0551, 0.0865, 0.0992, 0, 0.0906, 0.1233, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0072, 7e-04, 0.004, 0, 6e-04, 0.0066, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0072, 7e-04, 0.004, 0, 6e-04, 0.0066, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(1e-04, 0, 4e-04, 0, 0, 0, 0, 0, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.2682, 0.1802, 0.1939, 0.0429, 0.0468, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.2682, 0.1802, 0.1939, 0.0429, 0.0468, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.2541, 0.2147, 0.1835, 0.2557, 0.1848, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1243, 0.1254, 0.2513, 0.2366, 0.3984, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1243, 0.1254, 0.2513, 0.2366, 0.3984, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0653, 0.0146, 0.1667, 0, 0, 0.2687, 0.1263, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0174, 0.0374, 0.0143, 0, 0.0049, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0174, 0.0374, 0.0143, 0, 0.0049, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0213, 0, 0.0349, 0.0044, 0, 0.0209, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1181, 0.0492, 0.0967, 0.4638, 0.0369, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1181, 0.0492, 0.0967, 0.4638, 0.0369, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1312, 0.1179, 0.4502, 0.088, 0.2164, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0014, 0, 0, 0, 2e-04, 0.0049, 0, 0, 0.0036, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0014, 0, 0, 0, 2e-04, 0.0049, 0, 0, 0.0036, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0042, 0.0023, 0, 0, 0, 0.0052, 0.0025, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0204, 0.014, 0.0079, 2e-04, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0204, 0.014, 0.0079, 2e-04, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.019, 0.0096, 0.0081, 0.0164, 0.012, 0.013, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0175, 0.033, 0.002, 0.009, 0.0034, 0.0128, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0175, 0.033, 0.002, 0.009, 0.0034, 0.0128, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0506, 0.0319, 0.0205, 0.0919, 0.0107, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0581, 0.1851, 0, 0, 0.2228, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0581, 0.1851, 0, 0, 0.2228, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0114, 0.1019, 0.0088, 0, 0, 0.2994, 0.0329, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0584, 0.1664, 0.045, 0.0952, 0.1077, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0584, 0.1664, 0.045, 0.0952, 0.1077, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0244, 0.0083, 0.0313, 0, 0.0774, 0.0074, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0359, 0.1077, 0.0195, 0.0077, 0.035, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0359, 0.1077, 0.0195, 0.0077, 0.035, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.017, 0.0021, 0.022, 3e-04, 0.0291, 0.0035, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0371, 0.0204, 0.0132, 0.1458, 0.0674, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0371, 0.0204, 0.0132, 0.1458, 0.0674, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0208, 0.0116, 0.0143, 0.0029, 0.0632, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0138, 0.0442, 0.0721, 0.074, 0.0514, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0138, 0.0442, 0.0721, 0.074, 0.0514, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0127, 0.0215, 0.0504, 0.0436, 0.0663, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0024, 0, 0.0012, 0.0228, 0, 0.0217, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0024, 0, 0.0012, 0.0228, 0, 0.0217, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0023, 0.0032, 0, 0.0037, 9e-04, 0.0047, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0037, 0.0045, 0.0019, 0, 0.0069, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0037, 0.0045, 0.0019, 0, 0.0069, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0081, 0.0069, 0.003, 0, 0, 9e-04, 0.0029, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0907, 0, 0, 0, 0.2741, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0907, 0, 0, 0, 0.2741, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.002, 0, 0.0396, 0, 0, 0, 0.0391, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0.0227), c(0.0127, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0.0227), c(0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0472, 0, 0, 0, 0, 0, 0, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 6e-04, 0, 0.0493, 0.0594, 0, 0.1855, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 6e-04, 0, 0.0493, 0.0594, 0, 0.1855, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0.0161, 0.0044, 0, 0, 0.0069, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0081, 0.0022, 0.0165, 0.0212, 0, 0.0303, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0081, 0.0022, 0.0165, 0.0212, 0, 0.0303, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0144, 0.0239, 0.005, 0.0231, 0.014, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0035, 0, 0, 0, 0, 0.0252, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0035, 0, 0, 0, 0, 0.0252, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0714, 0.0445, 0.0401, 0.019, 0.0675, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0714, 0.0445, 0.0401, 0.019, 0.0675, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0456, 0.0249, 0.0137, 0, 0.02, 0.0669, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.003, 0, 0.0016, 0.0025, 0.0019, 0.0027, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.003, 0, 0.0016, 0.0025, 0.0019, 0.0027, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(7e-04, 0.0014, 7e-04, 7e-04, 0.0013, 0.001, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0016, 0, 0, 0.0132, 0, 0.0118, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0016, 0, 0, 0.0132, 0, 0.0118, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 1e-04, 0, 0.0032, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0756, 0.0403, 0.0137, 0, 0, 0, 0.0188, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0756, 0.0403, 0.0137, 0, 0, 0, 0.0188, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1068, 0.0979, 0.02, 0.1521, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1386, 0.0708, 0.1995, 0, 0.3062, 0.0192, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1386, 0.0708, 0.1995, 0, 0.3062, 0.0192, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0117, 0.0595, 0, 0, 0.2039, 0.0868, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0114, 0.0428, 0.0373, 0, 4e-04, 0, 0.1265, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0114, 0.0428, 0.0373, 0, 4e-04, 0, 0.1265, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0353, 0.034, 0.0331, 0.0227, 0.0034, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 5e-04, 0, 0.0028, 0.0047, 5e-04, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 5e-04, 0, 0.0028, 0.0047, 5e-04, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0071, 0, 0, 0, 0, 0.0141, 0, 0.0037, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0475, 0.0786, 0.1765, 0.0906, 0.0083, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0475, 0.0786, 0.1765, 0.0906, 0.0083, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0705, 0.065, 0.0629, 0.0705, 0.1129, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0046, 0.0021, 0.0041, 0, 0, 0, 0, 0.0074, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0046, 0.0021, 0.0041, 0, 0, 0, 0, 0.0074, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0123, 0.0116, 0.004, 0.0083, 0.0015, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0011, 0.0101, 0, 0.0061, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0011, 0.0101, 0, 0.0061, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.0048, 0.0021, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.262, 0.3094, 0.3366, 0.3853, 0.3204, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.4411, 0.3607, 0.3534, 0.5803, 0.4079, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0197, 0, 0, 0, 0, 0.0786, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0197, 0, 0, 0, 0, 0.0786, 0, 0, 0), :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0.006, 0, 0, 0, 4e-04, 0.005, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0241, 0.1613, 0.0185, 0, 0.0095, 0, 0.2372, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0241, 0.1613, 0.0185, 0, 0.0095, 0, 0.2372, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0641, 0.0397, 0.0027, 0.088, 0.0037, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.035, 0.0105, 0, 0.0159, 0, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.035, 0.0105, 0, 0.0159, 0, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0177, 0.0041, 0, 0.0032, 0.0035, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0268, 0.0473, 0, 0.0019, 0, 0.1396, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0268, 0.0473, 0, 0.0019, 0, 0.1396, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0.0124, 0.0165, 0, 0, 0.0225, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0553, 0.0671, 0, 0.006, 0, 0, 0.0093, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0553, 0.0671, 0, 0.006, 0, 0, 0.0093, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0431, 0, 0.0725, 0.0111, 0, 0.0385, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.1455, 0.0523, 0.062, 0.1139, 0.1092, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0098, 0, 0.0715, 0.0305, 0.2699, 0.0825, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.6273, 0.3138, 0.1276, 0.1701, 0.4489, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.2353, 0.1295, 0.2008, 0.0964, 0.5609, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0312, 0.003, 0.0215, 0.2304, 0.0427, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0312, 0.003, 0.0215, 0.2304, 0.0427, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0221, 0.0417, 0.0456, 0, 0.0407, 0.0427, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0494, 0.0187, 0.0183, 0.1651, 0.0516, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0494, 0.0187, 0.0183, 0.1651, 0.0516, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.037, 0.0546, 0.0541, 0, 0.0491, 0.0533, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0458, 0, 0, 0, 0.0902, 0.0081, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0458, 0, 0, 0, 0.0902, 0.0081, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0254, 0, 0.0329, 0, 0, 0, 0.0158, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0353, 0, 0, 0, 0, 0.1113, 0.0158, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0353, 0, 0, 0, 0, 0.1113, 0.0158, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0.0075, 0.0011, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0241, 0.0074, 0, 0, 0, 0.1084, 1e-04, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0241, 0.0074, 0, 0, 0, 0.1084, 1e-04, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 9e-04, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0958, 0.0733, 0.1585, 0.2817, 0.2536, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0958, 0.0733, 0.1585, 0.2817, 0.2536, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0602, 0.0506, 0.136, 0, 0.0453, 0.196, :
## cannot compute exact p-value with ties

CIBERSORT

## Warning in wilcox.test.default(c(0.050715897773675, 0.0589216303571212, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.050715897773675, 0.0589216303571212, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0318966041555209, 0.0508095079022262, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 9e-04, 0, 0, 0, 0, 0, 0),
## c(0.00998927271963148, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 9e-04, 0, 0, 0, 0, 0, 0), c(0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0,
## 0.150595294100848, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00732318173480844, 0.0133312289047236, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00732318173480844, 0.0133312289047236, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.00822387484636926, 0, 0, 0,
## 0.00137467512825642, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.089000329769136, 0.0556561921214293, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.089000329769136, 0.0556561921214293, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0457651525286324, 0.0229009785784177, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0171137861131678, 0.0174792417076714, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0171137861131678, 0.0174792417076714, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0.00505752713538209, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0720692087262833, 0.0311107582749746, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0602878161955419, 0.0854413624332458, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00387945492287396, 0.0183321857070058, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00387945492287396, 0.0183321857070058, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00812540810014259, 0, 0.00566558068227889, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0602090338783283, 0.0235375184477379, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0602090338783283, 0.0235375184477379, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0261781922446611, 0.0369721518040315, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0223605215308501, 0.020772858816945, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0223605215308501, 0.020772858816945, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0720073791097346, 0.038569324836885, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0587348946100486, 0.00181518709696392, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0587348946100486, 0.00181518709696392, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0353323257032854, 0.0574202273437429, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0816614219933261, 0.0355161783744101, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0816614219933261, 0.0355161783744101, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0345224773124627, 0.0305392202633606, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0979241038044601, 0.078250151364972, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0979241038044601, 0.078250151364972, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.110750985718031, 0.109212559537125, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00705661029649803, 0.00650356714702842, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00705661029649803, 0.00650356714702842, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.00782109688406625,
## 0.0739573605083729, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0535620408002784, 0, 0.0133267664120756, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0535620408002784, 0, 0.0133267664120756, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0582510627882573, 0.031531502461927, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0422742096194234, 0.109637959013854, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0422742096194234, 0.109637959013854, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0225370927263392, 0.0700382010163719, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0.0393189644862643,
## 0.158491540070273, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0.0393189644862643,
## 0.158491540070273, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0131375727202622, 0, 0, 0.0488424637294577, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0131375727202622, 0, 0, 0.0488424637294577, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.001, 0, 0.0229035270696558, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 8e-04, 0.0270383100740529, 0, : cannot
## compute exact p-value with ties

quanTIseq

## Warning in wilcox.test.default(c(0.00399975735091767, 0.0202122943787033, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00399975735091767, 0.0202122943787033, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0106234230323736, 0.0120660484795853, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0165097760250007, 0.0279658857720924, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0165097760250007, 0.0279658857720924, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0331792192078885, 0.0721540962543036, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0299625120235453, 0.0251496407576396, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0299625120235453, 0.0251496407576396, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0232240531090068, 0.0377878981728211, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0.0884899506757721,
## 7.21432290820029e-05, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0.0884899506757721,
## 7.21432290820029e-05, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00904689655345614, 0, 0.0479150231008549, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00435471117444115, 0.0366003452803578, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00985972201941608, 0.00143522968424654, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.0228099673146307, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.0228099673146307, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.0178381323159788,
## 0.0304709115102939, : cannot compute exact p-value with ties

MCP counter

## Warning in wilcox.test.default(c(0.352, 0.20425, 0.3145, 0.039375, 0.356125, :
## cannot compute exact p-value with ties

Epidish_BPRNACan

## Warning in wilcox.test.default(c(0, 0.0128250147706642, 0.073775146110546, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0128250147706642, 0.073775146110546, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0180087415504123, 0, 0.0421795551405441, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0247595922046391, 0.0136752776341425, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0110906635232662, 0.00662130735749346, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0206768766042594, 0.00694671247660056, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0206768766042594, 0.00694671247660056, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00489513829877941, 0, 0.0119472446002238, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00026256673679241, 0, 0,
## 0.000645501413739263, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00026256673679241, 0, 0,
## 0.000645501413739263, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(6.63551509348196e-05, 0.0155499555374713, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(6.63551509348196e-05, 0.0155499555374713, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000500748913054234, 0.000700033137566333, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.00201061428537586, 0,
## 0.00143651305612025, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.00201061428537586, 0,
## 0.00143651305612025, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 4.30128394147444e-06, 0,
## 8.86833815849158e-05, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000566592352196745, 0, 0, 0, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000566592352196745, 0, 0, 0, 0, 0, 0, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.00431901217834006, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.00431901217834006, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 6.86865741523341e-05, 0, 0, :
## cannot compute exact p-value with ties

DeconRNASeq_BPRNACan

## Warning in wilcox.test.default(c(0.0414441733845095, 0, 0, 0.0236766165859991, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0414441733845095, 0, 0, 0.0236766165859991, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0329418798545002, 0.018431958027428, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0214182813706074, 0.0303032073307191, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0214182813706074, 0.0303032073307191, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00078871493579856, 0, 0.0265713137607306, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.00866237949762366,
## 0.0267196827842361, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.00866237949762366,
## 0.0267196827842361, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.0390976195753702,
## 0.0170610493243694, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0952317443644208, 0, 0.0537525381080335, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0952317443644208, 0, 0.0537525381080335, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0768115488342718, 0.0565258281947652, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0924934556092932, 0.0210609941035026, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0722765577660607, 0.0693552241759562, :
## cannot compute exact p-value with ties

Epidish_BPRNACan3DProMet

## Warning in wilcox.test.default(c(0, 0.00312650176428612, 0.0635200941830254, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.00312650176428612, 0.0635200941830254, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00566756857926992, 0, 0.0310817039928062, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.018989884576028, 0, 0.00234280939434873, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.018989884576028, 0, 0.00234280939434873, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0332101978281179, 0.0035556416330297, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0117558010670953, 0, 0, 0, 0,
## 0.0479614899227165, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0117558010670953, 0, 0, 0, 0,
## 0.0479614899227165, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.00369106337182214, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.00050767803019754, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.00050767803019754, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000179132068542732, 0.0187082655275437, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000179132068542732, 0.0187082655275437, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.00245030189020479, 0,
## 0.00175493178009707, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.00245030189020479, 0,
## 0.00175493178009707, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 7.80398830706327e-05, 0,
## 0.00190071994104379, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0120511685343642, 0.0104107863861505, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000123696619175533, 0.00110772841957253, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000123696619175533, 0.00110772841957253, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000234413031910891, 0, 0, 0,
## 0.00156970501759933, : cannot compute exact p-value with ties

DeconRNASeq_BPRNACan3DProMet

## Warning in wilcox.test.default(c(0.0312733854216495, 0, 0, 0, 0,
## 0.00779678868281791, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0312733854216495, 0, 0, 0, 0,
## 0.00779678868281791, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00690750655895095, 0.0120528235112616, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0.0325748870140445, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.00273110121975689,
## 0.0165308743968938, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.00273110121975689,
## 0.0165308743968938, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.0389309374631316,
## 0.0135200686460485, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.044570514764391, 0, 1.86554204229805e-05, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.044570514764391, 0, 1.86554204229805e-05, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0243801552133373, 0.00217064719667247, :
## cannot compute exact p-value with ties

Epidish_BPRNACanProMet

## Warning in wilcox.test.default(c(0, 0.0102858199113633, 0.0741539862664183, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0102858199113633, 0.0741539862664183, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0162382012512861, 0, 0.037138160257393, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0199352585830779, 0.00188062345163386, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0199352585830779, 0.00188062345163386, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0393067508727525,
## 0.00302555934852301, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0145326934281952, 0.000981745914428781, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.0145326934281952, 0.000981745914428781, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00044538250800437, 0, 0.00663277539409557, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.00107172141602875, 0,
## 0.00053558568149227, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.00107172141602875, 0,
## 0.00053558568149227, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000391815532496155, 0.0183257123794917, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.000391815532496155, 0.0183257123794917, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.00103480998170117, 0.00119319823084139, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.002601839560081, 0,
## 0.00194447368983288, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0.002601839560081, 0,
## 0.00194447368983288, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 1.10323689590852e-05, 0,
## 0.000125551730083607, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0144652509581952, 0.0371273574899296, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0123265037828552, 0.00924156428082966, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.000776280507408971, 0, 0, 0,
## 0.00426994612246468, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0.000776280507408971, 0, 0, 0,
## 0.00426994612246468, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0.00148271911986737, 0,
## 0.000180771577201298, : cannot compute exact p-value with ties

DeconRNASeq_BPRNACanProMet

## Warning in wilcox.test.default(c(0.02605503330469, 0, 0, 0, 0,
## 0.0101195591044128, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.02605503330469, 0, 0, 0, 0,
## 0.0101195591044128, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.012697818615349, 0.0184203112413973, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0.00878952185722251:
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0.00878952185722251:
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.00180864643659513, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0), c(0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, : cannot
## compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0020451575638873, 0.0123301815261995, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0.0020451575638873, 0.0123301815261995, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0, 0, 0, 0, 0, 0.043839436993316,
## 0.012532350024578, : cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0510195623988836, 0, 0.0124407463042499, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0510195623988836, 0, 0.0124407463042499, :
## cannot compute exact p-value with ties

## Warning in wilcox.test.default(c(0.0172697557833526, 0.00402049376783505, :
## cannot compute exact p-value with ties